Cross Circulation: The circulation in a portion of the body of one individual of blood supplied from another individual.Vaginal Birth after Cesarean: Delivery of an infant through the vagina in a female who has had a prior cesarean section.Cesarean Section: Extraction of the FETUS by means of abdominal HYSTEROTOMY.Cephalopelvic Disproportion: A condition in which the HEAD of the FETUS is larger than the mother's PELVIS through which the fetal head must pass during a vaginal delivery.Microbiology: The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.Delivery, Obstetric: Delivery of the FETUS and PLACENTA under the care of an obstetrician or a health worker. Obstetric deliveries may involve physical, psychological, medical, or surgical interventions.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Helicobacter pylori: A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).Helicobacter Infections: Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.Carotid Arteries: Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.Antigens, Bacterial: Substances elaborated by bacteria that have antigenic activity.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Crisscross Heart: A developmental malformation of the heart characterized by a twisted but not defective atrioventicular connection. The abnormal rotation of the ventricular mass around its long axis results in the crossing of the inflow streams of the two ventricles. Other features include hypoplasia of the TRICUSPID VALVE and RIGHT VENTRICLE.Situs Inversus: A congenital abnormality in which organs in the THORAX and the ABDOMEN are opposite to their normal positions (situs solitus) due to lateral transposition. Normally the STOMACH and SPLEEN are on the left, LIVER on the right, the three-lobed right lung is on the right, and the two-lobed left lung on the left. Situs inversus has a familial pattern and has been associated with a number of genes related to microtubule-associated proteins.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Dextrocardia: A congenital defect in which the heart is located on the right side of the THORAX instead of on the left side (levocardia, the normal position). When dextrocardia is accompanied with inverted HEART ATRIA, a right-sided STOMACH, and a left-sided LIVER, the combination is called dextrocardia with SITUS INVERSUS. Dextrocardia may adversely affect other thoracic organs.Transposition of Great Vessels: A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.Cerebral Ventricles: Four CSF-filled (see CEREBROSPINAL FLUID) cavities within the cerebral hemispheres (LATERAL VENTRICLES), in the midline (THIRD VENTRICLE) and within the PONS and MEDULLA OBLONGATA (FOURTH VENTRICLE).Heart Septal Defects, Ventricular: Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.Vascular Cell Adhesion Molecule-1: Cytokine-induced cell adhesion molecule present on activated endothelial cells, tissue macrophages, dendritic cells, bone marrow fibroblasts, myoblasts, and myotubes. It is important for the recruitment of leukocytes to sites of inflammation. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, p154)Intercellular Adhesion Molecule-1: A cell-surface ligand involved in leukocyte adhesion and inflammation. Its production is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue.Receptors, Pattern Recognition: A large family of cell surface receptors that bind conserved molecular structures (PAMPS) present in pathogens. They play important roles in host defense by mediating cellular responses to pathogens.Cell-Derived Microparticles: Extracellular vesicles generated by the shedding of CELL MEMBRANE blebs.Blood Coagulation: The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.HMGB1 Protein: A 24-kDa HMGB protein that binds to and distorts the minor grove of DNA.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.HydrazinesCyclooxygenase Inhibitors: Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.Receptors, Endothelin: Cell surface proteins that bind ENDOTHELINS with high affinity and trigger intracellular changes which influence the behavior of cells.Cyclooxygenase 2 Inhibitors: A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.Receptor, Endothelin A: A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high affinity for ENDOTHELIN-1 and ENDOTHELIN-2.Cyclooxygenase 1: A constitutively-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes.Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.Outpatients: Persons who receive ambulatory care at an outpatient department or clinic without room and board being provided.Heart Auscultation: Act of listening for sounds within the heart.Auscultation: Act of listening for sounds within the body.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.Cost-Benefit Analysis: A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Emulsions: Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Fat Emulsions, Intravenous: Emulsions of fats or lipids used primarily in parenteral feeding.Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.Carbon Dioxide: A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.Hypoglycemic Agents: Substances which lower blood glucose levels.Forced Expiratory Volume: Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.Diabetes Mellitus, Experimental: Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.Vital Capacity: The volume of air that is exhaled by a maximal expiration following a maximal inspiration.

Effects of prostaglandin E(1) on the efficacy of xenogeneic extracorporeal pig liver perfusion in a canine model of acute liver failure. (1/42)

Xenogeneic extracorporeal liver perfusion (ECLP) has the potential to become an important tool in the management of patients with severe liver failure. We previously showed that xenogeneic pig liver perfusion may be prolonged for up to 9 hours by the administration of prostaglandin E(1) (PGE(1)). In this study, we used a canine model of acute liver failure to evaluate the effects of PGE(1) on the efficacy of ECLP as a liver-assist device. Liver failure was surgically induced in 12 beagle dogs, with a control group (group 1, n = 4) not connected to the ECLP circuit. Direct cross-circulation between the dogs and the ECLP circuit using a pig liver was performed without (group 2, n = 4) or with (group 3, n = 4) continuous administration of PGE(1) through the portal vein of the pig liver. The duration of cross-circulation in group 3 (9.4 +/- 1.2 hours) was significantly longer than in group 2 (4.3 +/- 1.0 hours). In addition, elevation of blood ammonia, total bile acid, and hyaluronic acid levels was less marked in group 3 compared with the other 2 groups. The ratio of branched-chain amino acids to aromatic amino acids was also improved in group 3. The mean survival time in group 3 (26.6 +/- 0.4 hours) was significantly longer than in group 1 (15.5 +/- 1.3 hours) or group 2 (17.1 +/- 2.9 hours). Continuous administration of PGE(1) to xenogeneic ECLP resulted in a significant improvement in both liver function and survival time of dogs with surgically induced liver failure.  (+info)

Influence of extracorporeal porcine liver perfusion on nonhuman primates: minimizing hemolysis improves subsequent survival. (2/42)

The aim of this study is to detect and analyze risk factors of direct cross-circulation between porcine liver and nonhuman primates before a clinical application of extracorporeal liver perfusion (ECLP) as a liver-assist method. Porcine livers were perfused with baboon blood in an ECLP system. Six healthy baboons were directly connected to the ECLP system with continuous prostaglandin E(1) administration. Cross-circulation was terminated in the following circumstances: (1) hepatic arterial or portal perfusion pressures elevated to 200 or 60 mm Hg, respectively; (2) massive exudative bleeding from the graft surface; or (3) bile output decreased to less than 5 microL/h/g of liver weight. In case 1, cross-circulation was continued for 10 hours. Severe macroscopic hemolysis occurred, and serum hemoglobin (s-Hb) concentration reached a peak of 47 mg/dL. The baboon died of acute renal failure 2 days later. Histological study of the perfused porcine liver showed marked microthrombi formation. In 3 of the later 5 cases, cross-circulation was discontinued when mild macroscopic hemolysis was observed. The duration of the 5 cross-circulations was maximally 6 hours (mean, 4.4 +/- 1.2 [SD] hours). Mean s-Hb concentration in the 5 cases was elevated to 14.8 +/- 5.8 mg/dL at the end of cross-circulation and decreased to the baseline level within 24 hours. These 5 baboons survived without organ dysfunction or immunologic disturbance. When severe hemolysis is avoided, direct cross-circulation using the ECLP system can be achieved without serious complications in nonhuman primates.  (+info)

Pulmonary vasoconstriction during regional nitric oxide inhalation: evidence of a blood-borne regulator of nitric oxide synthase activity. (3/42)

BACKGROUND: Inhaled nitric oxide (INO) is thought to cause selective pulmonary vasodilation of ventilated areas. The authors previously showed that INO to a hyperoxic lung increases the perfusion to this lung by redistribution of blood flow, but only if the opposite lung is hypoxic, indicating a more complex mechanism of action for NO. The authors hypothesized that regional hypoxia increases NO production and that INO to hyperoxic lung regions (HL) can inhibit this production by distant effect. METHODS: Nitric oxide concentration was measured in exhaled air (NO(E)), NO synthase (NOS) activity in lung tissue, and regional pulmonary blood flow in anesthetized pigs with regional left lower lobar (LLL) hypoxia (fraction of inspired oxygen [FIO2] = 0.05), with and without INO to HL (FIO2 = 0.8), and during cross-circulation of blood from pigs with and without INO. RESULTS: Left lower lobar hypoxia increased exhaled NO from the LLL (NO(E)LLL) from a mean (SD) of 1.3 (0.6) to 2.2 (0.9) parts per billion (ppb) (P < 0.001), and Ca2+-dependent NOS activity was higher in hypoxic than in hyperoxic lung tissue (197 [86] vs. 162 [96] pmol x g(-1) x min(-1), P < 0.05). INO to HL decreased the Ca2+-dependent NOS activity in hypoxic tissue to 49 [56] pmol x g(-1) x min(-1) (P < 0.01), and NO(E)LLL to 2.0 [0.8] ppb (P < 0.05). When open-chest pigs with LLL hypoxia received blood from closed-chest pigs with INO, NO(E)LLL decreased from 2.0 (0.6) to 1.5 (0.4) ppb (P < 0.001), and the Ca2+-dependent NOS activity in hypoxic tissue decreased from 152 (55) to 98 (34) pmol x g(-1) x min(-1) (P = 0.07). Pulmonary vascular resistance increased by 32 (21)% (P < 0.05), but more so in hypoxic (P < 0.01) than in hyperoxic (P < 0.05) lung regions, resulting in a further redistribution (P < 0.05) of pulmonary blood flow away from hypoxic to hyperoxic lung regions. CONCLUSIONS: Inhaled nitric oxide downregulates endogenous NO production in other, predominantly hypoxic, lung regions. This distant effect is blood-mediated and causes vasoconstriction in lung regions that do not receive INO.  (+info)

Cardiac effects of clinically available Kampo medicine assessed with canine isolated, blood-perfused heart preparations. (4/42)

Cardiac effects of 10 kinds of clinically available Kampo medicines were investigated: Kakkon-to (TJ-1), Dai-saiko-to (TJ-8), Boi-ogi-to (TJ-20), Chorei-to (TJ-40), Rokumi-gan (TJ-87), Tsu-do-san (TJ-105), Gosha-jinki-gan (TJ-107), San'o-shashin-to (TJ-113), Sairei-to (TJ-114) and Inchin-gorei-san (TJ-117). Chronotropic and inotropic effects were studied using canine isolated, blood-perfused heart preparations, while subcellular mechanisms were analyzed by measuring the drug-induced changes of the adenylate cyclase activity in the canine ventricular membrane preparation. Intracoronary injections of TJ-1, TJ-20, TJ-105 and TJ-113 increased the sinoatrial rate and developed tension of papillary muscle in a dose-related manner, which was significantly attenuated by the pretreatment of the preparations with beta-blocker propranolol. Meanwhile, the other extracts hardly affected these parameters. TJ-1, TJ-20 and TJ-113 increased the adenylate cyclase activity in a dose-related manner, but their potency was significantly less compared with that by an equivalent concentration of isoproterenol. Moreover, TJ-105 did not increase the adenylate cyclase activity. These results suggest that the positive chronotropic and inotropic effects of TJ-1, TJ-20, TJ- 105 and TJ-113 may be exerted through the direct stimulation of the beta-adrenoceptor and/or the norepinephrine release from the postganglionic nerve terminals in the heart.  (+info)

Cardiac effects of a selective rho-associated kinase inhibitor, Y-27632, assessed in canine isolated, blood-perfused heart preparations. (5/42)

Chronotropic, inotropic and coronary effects of Y-27632 ((+)-(R)-trans-4-(1-aminoethyl)-N-(4-pyridyl) cyclohexanecarboxamide dihydrochloride, monohydrate), a specific inhibitor of Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK), were assessed using canine isolated, blood-perfused heart preparations. Y-27632 slightly enhanced sinoatrial automaticity and significantly increased coronary blood flow, while it decreased ventricular contraction. The concentrations of Y-27632 needed to cause the currently observed changes were similar to those inhibiting ROCK in a previous in vitro study. These results suggest that the constitutional ROCK in the heart mainly regulates the ventricular contractility and coronary vascular tone rather than the sinoatrial automaticity.  (+info)

Standardization of an isolated pig heart preparation with parabiotic circulation: methodological considerations. (6/42)

In the present study we standardized an experimental model of parabiotic circulation of isolated pig heart. The isolated heart was perfused with arterial blood from a second animal as support and submitted to regional ischemia for 30 min, followed by total ischemia for 90 min and reperfusion for 90 min. Parameters for measurement of ventricular performance using different indices measured directly or indirectly from intraventricular pressure were defined as: maximum peak pressure, final diastolic pressure, pressure developed, first derivative of maximum pressure (dP/dt max), first derivative of minimum pressure (dP/dt min), systolic stress of the left ventricle (sigmas), and maximum elastance of the left ventricle. Isolated hearts subjected to regional and global ischemia presented significant worsening of all measured parameters. Less discriminative parameters were dP/dt max and dP/dt min. Elastance was the most sensitive parameter during the reperfusion period, demonstrating an early loss of ventricular function during reperfusion. The model proved to be stable and reproducible and permitted the study of several variables in the isolated heart, such as ischemia and reperfusion phenomena, the effects of different drugs, surgical interventions, etc. The model introduces an advantage over the classical models which use crystalloid solutions as perfusate, because parabiotic circulation mimics heart surgery with extracorporeal circulation.  (+info)

Cross-circulation study of natriuretic factors in postobstructive diuresis. (7/42)

To study the role of circulating natriuretic factors in the postobstructive diuresis that occurs after relief of bilateral, but not unilateral ureteral ligation, cross-circulation was carried out between normal recipient rats and donor rats have either 24-h bilateral (BUL) or unilateral (UUL) ureteral ligation. With BUL donors, there was a rapid marked increase in sodium and water excretion in the recipient rats, sustained for 80-140 min, with a peak approximately 10 times control values. With UUL donors, no significant natriuretic response occurred. Changes in glomerular filtration rate, renal plasma flow, blood pressure, hematocrit, or circulating levels of aldosterone or Pitressin did not explain the diuresis-natriuresis produced by cross-circulation with BUL donors. Differences in the intrinsic renal damage produced by bilateral as compared to unilateral ureteral obstruction did not appear to account for this response, since UUL donors given an acute urea load and urine reinfusion caused a similar diuresis-natriuresis. Moreover, normal donor rats given a urea load also caused a diuresis-natriuresis nearly equal to that produced by BUL rats, and the relationship between increased urea excretion and sodium excretion or urine flow in the recipients was not different in the two groups. Total urine reinfusion for 3 h in donor rats produced a significant, although less marked, diuresis-natriuresis in recipient animals, with only a slight elevation of the blood urea nitrogen level, much less increase in urea excretion rate, and no significant relationship between urea excretion and sodium excretion or urine flow. The results indicate that potent natriuretic factors, which act by decreasing the tubular reabsorption of sodium and water, are present in the blood of rats with bilateral, but not unilateral, ureteral ligation. High blood and urine urea levels appear to be the factors responsible for the marked natriuresis-diuresis occurring in normal rats during cross-circulation with BUL donors, although suggestive evidence of other natriuretic factors in urine reinfused intravenously was also obtained. The data suggest that urea osmotic diuresis is an important mechanism for determining the striking difference between the postobstructive diuresis observed after relief of bilateral as compared to unilateral ureteral ligation.  (+info)

Detrimental effects after dobutamine infusion on rat left ventricular function: mechanical work and energetics. (8/42)

We have previously reported that continuous infusion of dobutamine into the coronary artery induces positive inotropic effects but induces no detrimental effects in cross-circulated, excised normal rat hearts and even in Ca2+ overload-induced contractile failing rat hearts. However, we hypothesized that some detrimental effects on left ventricular (LV) function are induced after continuous dobutamine infusion and the following clearance of blood dobutamine, as is the case after beta-adrenergic receptor stimulation. To test this hypothesis, we investigated LV mechanical work and energetics in the same type of preparations that underwent continuous dobutamine infusion and clearance of blood dobutamine. We found that both mean end-systolic pressure and systolic pressure-volume area (PVA; a measure of total mechanical energy per beat) at midrange LV volume were significantly (P < 0.01) decreased. The mean myocardial oxygen consumption per beat intercept, which is composed of for the total Ca2+ handling in excitation-contraction coupling and basal metabolism, of the and PVA linear relation was also significantly (P < 0.05) decreased (n=8). The mean slope of the linear relation was unchanged in such hearts. Post-dobutamine basal metabolism was unchanged (n = 5 of the 8 hearts). The moderate proteolysis of a cytoskeleton protein, alpha-fodrin was identified (n = 7 of the 8 hearts with the decreased intercept), after clearance of blood dobutamine. In agreement with our hypothesis, the detrimental effect of the post-beta-adrenergic receptor stimulation was induced by a moderate concentration of dobutamine; we found systolic dysfunction due to the impairment of Ca2+ handling in excitation-contraction coupling in the rat LV and proteolysis of a cytoskeleton protein, alpha-fodrin.  (+info)

Vaginal birth leads to changes in the development of offsprings microbiomes not seen among mice born via C-section, which researchers suspect might contribute to the weight differences.. 0 Comments. ...
The cardiovascular effects of a new class I antiarrhythmic drug, bisaramil, were examined using canine isolated, blood-perfused heart preparations. Bisaramil exerted negative chronotropic, inotropic and dromotropic effects as well as coronary vasodilator action, which are qualitatively the same as those of classical class I drugs. The selectivity of bisaramil for the intraventricular conduction vs the other cardiac variables was compared with that of disopyramide and flecainide. Bisaramil was the most selective for intraventricular conduction, while it was the least selective for ventricular muscle contraction. We conclude that bisaramil may become a useful antiarrhythmic drug with less cardiac adverse effects.. ...
Although exercise reduces several cardiovascular risk factors associated with obesity/diabetes, the metabolic effects of exercise on the heart are not well known. This study was designed to investigate whether high intensity interval training (HIT) is superior to moderate intensity training (MIT) in counteracting obesity-induced impairment of left ventricular (LV) mechanoenergetics and function. Diet-induced obese C57BL/6J (DIO) mice, displaying a cardiac phenotype with altered substrate utilization and impaired mechanoenergetics, were subjected to a sedentary lifestyle or 8-10 weeks of isocaloric HIT or MIT. Although both modes of exercise equally improved aerobic capacity and reduced obesity, only HIT improved glucose tolerance. Hearts from sedentary DIO mice developed concentric LV remodelling with diastolic and systolic dysfunction, which was prevented by both HIT and MIT. Both modes of exercise also normalized LV mechanical efficiency and mechanoenergetics. These changes were associated ...
Cardiac twitch contractions were simulated by Huxleys sliding filament crossbridge muscle model. Huxleys model was extended to include cardiac twitch contractions with a model structure having...
3 patients were enrolled in each of 3 study cohorts. There three cohorts were given differing, incrementally larger doses of this phase I drug. The same safety measures are being obtained on all patients. Efficacy measures were individualized as enrolllees do not have the same underlying vascular anomaly. The study is structured to include a 24 month drug-phase and a 24 month follow-up phase. The study is now closed to enrollment ...
parabiosis definition: 1. the union of two animals, naturally or experimentally, as by blood circulatory connections 2. the temporary and reversible suspension of a vital life process 3. the living together of two or more different species, as in mixed f...
Parabiosis and young blood transfusion have remarkable anti-aging effects. How to replicate the anti-aging effects of parabiosis and young blood transfusion
Two-dimensional echocardiography can provide serial cross-sectional images of the left ventricular cavity. We examined whether such serial images from steady-state ejecting hearts would allow three-dimensional reconstruction and accurate volume estimation without major geometric assumptions. Cross-circulated, paced dog hearts were suspended in a blood-filled tank. Serial cross-sectional images were taken at 3-mm intervals along the vertical axis. Left ventricular cavity and muscle areas of each image were planimetered with a light-pen system and summated for volume: total volume = sigma (areas x 3 mm). Direct left ventricular volume was measured through the cardiac cycle with a volumetric chamber connected to a balloon in the ejecting left ventricle. In six hearts, 67 separate direct volume measurements (range 9.5--54.7 ml) from various points in the cardiac cycle were compared with the simultaneous echo volume measurements. By least squares linear regression, echo volume = 1.01 (direct volume) ...
Leviticus 17:11: For the life of the flesh is in the blood: and I have given it to you upon the altar to make an atonement for your souls: for it is the blood that maketh an atonement for the soul.. The Oxford Dictionary of Biology defines blood as "a fluid body tissue that acts as a transport medium within an animal." The heart dilates and contracts, sending blood coursing through veins and arteries, delivering oxygen and nutrients to tissues and organs, and carrying waste matter from the center to the periphery for elimination.. A new frontier in parabiosis ("the anatomical joining of two individuals, especially artificially in physiological research"), known as heterochronic parabiosis, entails flooding an older organism with blood from a younger organism.. In heterochronic parabiosis, plasma (clear, yellowish fluid of vertebrates) is separated out from the blood whole and combined with platelets, before the combined fluids are delivered to the recipients circulatory system (arteries, ...
Schuurman, R., Brambilla, D., De Groot, T., Huang, D., Land, S., Bremer, J., ... Boucher, C. (2002). Underestimation of HIV Type I drug resistance mutations: Results from the ENVA-2 genotyping proficiency program. AIDS Research and Human Retroviruses, 18, 243 - 48. ...
So maybe Count Dracula had it right after all. It looks like that young blood has some really good stuff in it. The lab of Tony Wyss-Coray at Stanford has been studying the causes of the aging of the brain. As baby boomers get older and older they get more and more interested in how to keep their brains young.. The Wyss-Coray lab used parabiosis to see if there might be something in the blood that regulates brain aging. Parabiosis is a surgical technique that connects the circulatory systems of two mice. It is sort of like taking two mice and turning them into Siamese twins. Sorry mice, Im sure it is no fun, but it is for the sake of science. For controls they connected young mice to young mice, and old mice to old. Not surprisingly, nothing much happened. But when they connected young mice to old mice, Eureka! The brains of the old mice started behaving like they were much younger! The brain stem cells, which normally slow down in old mice, became active and divided more. Neurogenesis, the ...
So maybe Count Dracula had it right after all. It looks like that young blood has some really good stuff in it. The lab of Tony Wyss-Coray at Stanford has been studying the causes of the aging of the brain. As baby boomers get older and older they get more and more interested in how to keep their brains young.. The Wyss-Coray lab used parabiosis to see if there might be something in the blood that regulates brain aging. Parabiosis is a surgical technique that connects the circulatory systems of two mice. It is sort of like taking two mice and turning them into Siamese twins. Sorry mice, Im sure it is no fun, but it is for the sake of science. For controls they connected young mice to young mice, and old mice to old. Not surprisingly, nothing much happened. But when they connected young mice to old mice, Eureka! The brains of the old mice started behaving like they were much younger! The brain stem cells, which normally slow down in old mice, became active and divided more. Neurogenesis, the ...
Pressure unloading represents the only effective therapy in increased afterload-induced left ventricular hypertrophy (LVH) as it leads to myocardial reverse remodeling (reduction of increased left ventricular mass, attenuated myocardial fibrosis) and preserved cardiac function. However, the effect of myocardial reverse remodeling on cardiac mechanoenergetics has not been elucidated. Therefore, we aimed to provide a detailed hemodynamic characterization in a rat model of LVH undergoing pressure unloading. Pressure overload was induced in Sprague-Dawley rats by abdominal aortic banding for 6 (AB 6th week) or 12 weeks (AB 12th week). Sham operated animals served as controls. Aortic debanding procedure was performed after the 6th experimental week (debanded 12th week) to investigate the regression of LVH. Pressure unloading resulted in significant reduction of LVH (heart weight/tibial length ratio: 0.38±0.01 vs. 0.58±0.02g/mm, cardiomyocyte diameter: 18.3±0.1 vs. 24.1±0.8µm debanded 12th week ...
The aim of the present study was to characterize the mechanoenergetic alterations in a rat model of LVH undergoing pressure unloading therapy using LV P-V analysis method. According to our best knowledge, this is the first study demonstrating that the regression of LVH by pressure unloading leads not only to reversed myocardial contractility augmentation and restored diastolic function, but also to maintained cardiac mechanoenergetics.. According to Laplaces law, when the pathological stimulus of sustained pressure overload emerges, the myocardial wall thickness increases to normalize wall tension (18). This maladaptive response reaction, also known LVH, is characterized by increased expression of sarcomeric proteins with subsequent enlargement of the cardiomyocytes, ECM remodeling (10), and decreased capillary density (39). The reversibility of these alterations has been already proven by numerous previous works, since they demonstrated that the regression of preestablished pathological ...
This paper reveals several unexpected characteristics of the recirculation and homing pattern of NKT cells and elucidates key biochemical and molecular mechanisms underlying these unusual properties. Although sinusoidal retention and crawling are well documented behaviors for many cell types, this mode of locomotion is transient, limited to the acute phase of immune response for effector T cells (Bartholomäus et al., 2009), monocytes (Auffray et al., 2007), and PMNs (Phillipson et al., 2006; McDonald et al., 2010) invading an organ or to a maturation step for immature B cells in the bone marrow (Pereira et al., 2009). In the case of NKT cells (Geissmann et al., 2005), the results of the long-term parabiosis experiments presented in this study imply that this behavior can be prolonged for weeks and, therefore, that these innate-like lymphocytes constitutively wander within the confines of the sinusoid capillary bed of the liver for periods of time that can exceed their lifespan. This is ...
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TY - JOUR. T1 - Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy. AU - Chen, Jiankang. AU - Chen, Jianchun. AU - Neilson, Eric G.. AU - Harris, Raymond C.. PY - 2005/12/9. Y1 - 2005/12/9. N2 - Loss of functioning nephrons stimulates the growth of residual kidney tissue to augment work capacity and maintain normal renal function. This growth largely occurs by hypertrophy rather than from hyperplasia of the remaining nephrons. The signaling mechanisms that increase RNA and protein synthesis during compensatory renal hypertrophy are unknown. This study found that the remaining kidney hypertrophied 42% by 16 d after unilateral nephrectomy (UNX) in DBA/2 mice. Immunoblotting analysis revealed increased phosphorylation of the 40S ribosomal protein S6 (rpS6) and the eukaryotic translation initiation factor (eIF) 4E-binding protein 1 (4E-BP1), the two downstream effectors of the mammalian target of rapamycin (mTOR). The highly specific mTOR inhibitor rapamycin blocked ...
Using an isolated canine heart preparation, the myocardial norepinephrine pool was labeled by injecting tritiated norepinephrine into the blood perfusing the heart. The extraction of the norepinephrine during a single circulation through the coronary bed was shown to be large (74%). As the isotopic material, which was extracted, was released spontaneously from the norepinephrine pool 75% to 88% of it was metabolized before appearing in the coronary venous blood. The chief metabolite has been demonstrated to be normetanephrine which accounts for 39.0% to 61.7% of the spontaneously released norepinephrine. Because of this it is concluded that catechol-O-methyl transferase is the enzyme primarily responsible for the metabolic inactivation of norepinephrine in the canine heart. When release was increased by the injection of tyramine, more of the released norepinephrine appeared unmetabolized in coronary venous blood, suggesting that the enzymatic process by which norepinephrine is inactivated may be ...
TY - JOUR. T1 - The harmful effects of ventricular distention during postischemic reperfusion. AU - Lucas, S. K.. AU - Schaff, H. V.. AU - Flaherty, J. T.. AU - Gott, Vincent L. AU - Gardner, T. J.. PY - 1981. Y1 - 1981. N2 - To assess the effects of left ventricular distention during the early reperfusion period following ischemic arrest, 16 canine heart preparations were subjected to 45 minutes of hypothermic (27°C) cardioplegic arrest and normothermic reperfusion. Isovolumic left ventricular developed pressure and rate of rise of left ventricular pressure (dP/dt) were measured with an intraventricular balloon; endocardial/epicardial flow ratios were determined with microspheres; and myocardial gas tensions were monitored with mass spectrometry. During early reperfusion, Group 1 hearts (n=8) were not distended (end-diastolic pressure = 0). Group 2 hearts (n = 8) were subjected to an enddiastolic pressure of 20 mm Hg for the initial 15 minutes of reperfusion. Group 2 hearts demonstrated ...
Lung transplantation, the only life-saving therapy for an increasing population of patients with end-stage lung disease, is severely limited by the number of available donor organs. Currently, up to 80% of donor lungs are rejected for serious but potentially reversible injuries. Since the beginning of transplantation in 1960s, clinicians and scientists have been trying to address the critical shortage of donor organs.. Now, a multidisciplinary team from Columbia Engineering and Vanderbilt University has - for the first time - demonstrated in a clinically relevant model that severely damaged lungs can be regenerated to meet transplantation criteria. In a study, the researchers describe the cross-circulation platform that maintained the viability and function of the donor lung and the stability of the recipient for 36 to 56 hours.. As Brandon Guenthart, a lead author of the study, explains "to support lung recovery and to demonstrate cellular regeneration, we had to pursue a radically different ...
Paniz Kamran is the author of this article in the Journal of Visualized Experiments: 마우스의 Parabiosis : 자세한 프로토콜
Teri Sforza is one of the lead reporters on the OCR/SCNG probe of fraud, abuse and death in the Southern California addiction treatment industry. Our "Rehab Riviera" coverage won first place for investigative reporting from the California Newspaper Publishers Association, first place for projects reporting from Best of the West and is a finalist for the National Institute for Health Care Management Foundations print award, competing with the New York Times, the Washington Post and ProPublica. Sforza birthed the Watchdog column for The Orange County Register in 2008, aiming to keep a critical (but good-humored) eye on governments and nonprofits, large and small. It won first place for public service reporting from the California Newspaper Publishers Association in 2010. She also contributed to the OCRs Pulitzer Prize-winning investigation of fertility fraud at UC Irvine, covered what was then the largest municipal bankruptcy in Americas history, and is the author of "The Strangest Song," the ...
You know how important human blood donors are. The same applies in veterinary medicine. Heres a look at donor dogs, blood banks and how the process works.
An isolated blood-perfused pig heart preparation to study myocardial perfusion with blood-pool gadolinium-chelate enhanced ultrafast MRI. High-power gradient MR- ...
New Japan Pro Wrestling (新日本プロレス Shin Nihon Puroresu) − japońska federacja wrestlingu założona w styczniu 1972 roku przez Antonio Inokiego. W 2005 roku Inoki sprzedał federację dla firmy Yukes, która w 2012 roku sprzedała ją dla Bushiroad. Obecnie prezesem federacji jest Naoki Sugabayashi (od września 2013)[2], a prezydentem Katsuhiko Harada (od lutego 2016)[3]. NJPW jest największą federacją wrestlingu w Japonii i drugą na świecie (po WWE). W latach 1972-1986 federacja należała do National Wrestling Alliance. Największą galą NJPW jest January 4 Dome Show, która jest organizowana od 1992 roku. Od 2007 roku gala jest nazywana Wrestle Kingdom. Głównym bookerem federacji jest Gedo[4]. 1 grudnia 2014 roku powstała platforma internetowa NJPW World, na której możliwe jest oglądanie gal federacji[5]. ...
The DEA announced the popular herbal analgesic kratom would be classified as a Schedule I drug in September 2016, despite public outcry and scant evidence of danger.
Canine heart disease can be easily overlooked unless the pet parent is aware of the early warning signs. Learn to recognize the indicators of heart issues.
Real people, Real dogs, Real recoveries! Canine Heart Disease- Alternative treatments and therapies for dogs suffering from valvular disease to dilated cardiomyopathy.
Hypertension can lead to hypertrophic heart disease is a multi-factorial, multi-scale problem in which altered whole body hemodynamics and neurohormonal factors lead to a complex growth and remodeling response in the heart. The cells and extracellular matrix in the myocardium initially compensate to the abnormal environmental factors with altered gene expression, changes in contractile and mechanoenergetic function, cell and tissue structural remodeling, in turn further affecting circulatory dynamics and often leading to decompensation and failure. The goal of this project is to integrate novel cell signaling models of myocyte hypertrophy into organ-level continuum models of ventricular growth, remodeling and mechanoenergetics coupled to hemodynamic models of systemic hypertension, and validate these multi-scale models with experiments in rats subjected to ventricular hemodynamic overload and treated with drugs that target key response pathways. The resulting model systems will enable ...
Occasionally during an emergency or for a serious illness a dog may require a lifesaving blood transfusion. This is most commonly needed due to internal organ bleeding caused by trauma, from ingesting a toxin, particularly rat baits or illnesses like anaemia.. Some veterinary clinics have their own canine blood bank set up with stores of blood on hand for these situations. Other veterinary clinics may have a list of potential blood donor candidates that they can call on to give blood in the case of emergency. Like humans, dogs do have different blood types and can even have more than one blood type in their system. Cross matching of blood type between donor and recipient will be undertaken before giving a transfusion.. The process of taking the blood is usually fairly simple and can be done on most dogs without sedating them. The process involves very little discomfort but the dog will be required to sit still and calm for up to 15 minuets while the blood is being drawn. An ideal blood donor ...
BioCytics© was incorporated in 2005 in Huntersville, North Carolina. It is being incubated by Carolina BioOncology Institute (CBI), a cancer treatment and Phase I drug testing facility. BioCytics© was founded by Dr. John Powderly, MD, medical board certified oncologist and a certified physician investigator (CPI), who is also President of CBI.. ...
by Dog Spectrum.com , Nov 3, 2016 , Tips. Althоugh thеrе is no cure fоr thе common саuѕеѕ of hеаrt fаilurе in dоgѕ, thеrе аrе treatments available thаt саn grеаtlу improve and еxtеnd уоur dоgѕ lifе. If уоur dog has bееn diаgnоѕеd with hеаrt fаilurе аnd clinical signs аrе viѕiblе, it is likеlу that your ...
Drug testing in the home and the workplace has become a necessity because of widespread prescription drug abuse. Families are deteriorating because of loved ones becoming addicted to illicit and prescription drugs. Drug abuse often starts at the bathroom cabinet. Check it regularly and dispose of outdated or unfinished prescriptions in a responsible way.. The average employer is unknowingly wasting thousands of dollars a year due to drug related workplace issues. Drug testing your employees saves lives and helps prevent addiction.. Every drug test kit supplied by us is made to the highest standard ensuring the result is as reliable and accurate as the last. Always follow manufacturers recommendations when testing, otherwise you may get an erroneous result. ...
TY - JOUR. T1 - Structural changes in the proximal tubule of kidneys from hypophysectomized rats.. AU - Evan, Andrew. AU - Simone, P. G.. AU - Solomon, S.. AU - Loker, E. F.. PY - 1972/10. Y1 - 1972/10. UR - http://www.scopus.com/inward/record.url?scp=0015414239&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0015414239&partnerID=8YFLogxK. M3 - Article. C2 - 5077377. AN - SCOPUS:0015414239. VL - 174. SP - 265. EP - 277. JO - Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology. JF - Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology. SN - 0003-276X. IS - 2. ER - ...
The ability of a numerical procedure to detect and to localize two experimentally induced, epicardial dipolar generators was tested in 24 isolated, perfused rabbit heart preparations, suspended in an electrolyte-filled spherical tank. Electrocardiograms were recorded from 32 electrodes on the surface of the test chamber before and after placement of each of two epicardial burns. The second lesion was located either 180 degrees, 90 degrees, or 45 degrees from the first. Signals were processed by iterative routines that computed the location of one or two independent dipoles that best reconstruced the observed surface potentials. The computed single dipole acounting for 99.68% of root mean sequare (RMS) surface potential recorded after the first burn was located 0.26 +/- 0.10 cm from the centroid of the lesion. Potentials recorded after the second lesions were fit with two dipoles that accounted for 99.36 +/- 1.51% of RMS surface potentials and that were located 0.42 +/- 0.26 cm and 0.57 +/- 0.49 ...
By Anushree Madappa On 02/27/18. On Monday, a federal judge of the U.S. District Court for the Southern District of New York dismissed a request to reclassify marijuana - currently a Schedule I drug, leaving the plaintiffs in a limbo after many states have legalized marijuana for medical and recreational purposes.. The plaintiffs - Marvin Washington, Dean Bartell, Alexis Bartell, Jose Belen, Sebastien Cotte, Jagger Cotte, along with the Cannabis Cultural Association Inc. - filed the petition challenging classification of marijuana as a Schedule I drug, hoping that its reclassification would pay way for legalization of cannabis across the nation. They sued Attorney General Jeff Sessions, the Department of Justice and the Drug Enforcement Administration (DEA) in the federal court.. They petitioners claimed that the "current scheduling of marijuana violates due process because it lacks a rational basis.". For decades, Marijuana has been under the Schedule I category of the Controlled Substances ...
need the icd 9 diagnosis code and ms drg along with the icd 10 and icd 10 pcs codes what code is assigned for a patient admistted for azathioprine I drug induced aplastic anemia the patient has peripheral neuropathy of multiple joints ...
I must give some history before getting to my question. My Chihuahua Sparky recently died from canine congestive heart failure. I did not realize he had
Patients with chronic constipation benefit from treatment with 5-hydroxytryptamine 4 (5-HT4) receptor agonists. However, the first-generation 5-HT4 receptor agonists cisapride and tegaserod were withdrawn from the market owing to rare cardiovascular adverse events, which were not 5-HT4-receptor-related, but due to the lack of selectivity of these drugs. Here we report the nonclinical cardiovascular profile of the selective 5-HT4 receptor agonist prucalopride. To assess its non-5-HT4 receptor-mediated effects on cardiovascular electrophysiological parameters, in vitro studies were performed in human ether-a-go-go-related gene-transfected cells, guinea pig ventricular myocytes and papillary muscle preparations, rabbit and dog Purkinje fibers, and the Langendorff rabbit heart. In vivo experiments were performed in a rabbit model for drug-induced proarrhythmogenesis, in anesthetized guinea pigs, and anesthetized and conscious dogs. In addition, human platelet aggregation and coronary artery ...
Known on the street as a "club drug," LSD is typically taken in tab form, and is active in very small quantities. LSD is not considered physically addictive, which simply means it does not produce withdrawal symptoms like cramps, chills, and other flu-like symptoms in users who stop taking the drug after chronic use. LSD users quickly develop a high degree of physical tolerance for the drug, however, which means they require more and more acid to achieve the same high as before. There is also the risk of psychological addiction among LSD users, and for this reason, LSD is classified as a Schedule I drug by the DEA, meaning it has a severe potential for psychological or physical abuse.. People who use LSD experience a "trip," or a visual hallucination, which can last upwards of 12 hours, and may include changes in sense or perception of time; intensified feelings and sensory experiences; seeing, touching, hearing or smelling things in a distorted way; and perceiving things that do not exist. The ...
http 21 C.F.R. § 1308.11(b)-(f) (complete listing of Schedule I drugs and substances); see also 21 C.F.R. § 1308.11(g) (temporary listing of substances subject to emergency scheduling ...
"Circulation. 116: 443. Archived from the original on 15 October 2015.. *^ Loria V, Dato I, Graziani F, Biasucci LM (2008). " ... "Southern Cross Healthcare Group. Archived from the original on 3 March 2014. Retrieved 15 September 2013.. ... "Circulation. 102 (10): 1082-85. doi:10.1161/01.CIR.102.10.1082. PMID 10973834. Archived from the original on 5 July 2011.. ... "Circulation: Cardiovascular Quality and Outcomes. 9 (3): 257-264. doi:10.1161/CIRCOUTCOMES.115.002224. PMC 4940126 . PMID ...
Southern Cross Healthcare Group. [15 September 2013].. *^ Faxon, D. P. Atherosclerotic Vascular Disease Conference: Executive ... Circulation. 1 June 2004, 109 (21): 2595-2604. PMID 15173041. doi:10.1161/01.CIR.0000128517.52533.DB.. ... Southern Cross Healthcare Group. [15 September 2013]. (原始内容存档于2014年3月3日).. ... Circulation. 1 June 2004, 109 (21): 2595-2604. doi:10.1161/01.CIR.0000128517.52533.DB.. ...
Ballou LM, Cross ME, Huang S, et al. (2000). "Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 ... 1999). "Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age". Circulation. 100 ( ...
Underwood and Cross, James (2009). General and Systematic Pathology. London, UK: Churchhill livingstone. p. 279. Kannel, WB; ... Meta-analysis of prospective studies". Circulation. 102 (10): 1082-85. doi:10.1161/01.CIR.102.10.1082. PMID 10973834. Archived ... McPherson, R; Tybjaerg-Hansen, A (19 February 2016). "Genetics of Coronary Artery Disease". Circulation Research. 118 (4): 564- ... Southern Cross Healthcare Group. Archived from the original on 3 March 2014. Retrieved 15 September 2013. Faxon, D. P. (1 June ...
American Red Cross. CPR/AED for the Professional Rescuer (participant's manual). Yardley, PA: StayWell, 2006. (page 63). U.S. ... Shurlock, B (18 December 2007). "Pioneers in cardiology: Frank Pantridge, CBE, MC, MD, FRCP, FACC" (PDF). Circulation. 116 (25 ... "CPR Adult Courses". American Red Cross. Archived from the original on 3 July 2007. Retrieved 2007-06-28. "Cardiopulmonary ... PMC 555899 . Sudden Cardiac Arrest Foundation American Heart Association: Learn & Live American Red Cross: Learn About ...
"The American Red Cross Unveils Innovative New First Aid and CPR/AED Training Programs". American Red Cross. April 4, 2006. ... Wilkes-Barre News, August 22, 2007 "Part 10.3: Drowning". Circulation. American Heart Association. 112 (24): 133-135. November ... From 1976 to 1985, the choking-rescue guidelines of the American Heart Association and of the American Red Cross taught ... From 1986 to 2005, the published guidelines of the American Heart Association and the American Red Cross recommended only the ...
British Red Cross; St Andrew's Ambulance Association; St John Ambulance (2006). First Aid Manual: The Authorised Manual of St. ... Epinephrine does appear to improve short-term outcomes such as return of spontaneous circulation. Some of the lack of long-term ... If high-quality CPR has not resulted in return of spontaneous circulation and the person's heart rhythm is in asystole, ... Chugh, S. S.; Kelly, K. L.; Titus, J. L. (2000-08-08). "Sudden cardiac death with apparently normal heart". Circulation. 102 (6 ...
"Emergency Cardiovascular Care Revisions for the professional rescuer" (DOC). American Red Cross. Retrieved 2007-06-15. Handley ... Circulation. 95 (8): 2174-2179. doi:10.1161/01.CIR.95.8.2174. ISSN 0009-7322. PMID 9133531. "Physical Intervention: Life ... Most organisations recommend the use of some sort of barrier between rescuer and patient to reduce cross infection risk. One ... to minimise the possibility of cross infection (in either direction). Barriers available include pocket masks and keyring-sized ...
Circulation. 2004 Jun 15;109(23 Suppl 1):III27-32. Review. Nohria A, Gerhard-Herman M, Creager MA, Hurley S, Mitra D, Ganz P ( ... This can make cross-sectional comparisons of %FMD difficult. Endothelial dysfunction was found in approximately half of women ... This is very important at the focal points of circulation where there is lots of blood flowing at one point so it is important ... Circulation. 2004 Jun;109(23 Suppl 1):III27-32. Bharath, Leena P.; Ruan, Ting; Li, Youyou; Ravindran, Anindita; Wan, Xin; Nhan ...
Circulation Research. 81 (5): 643-50. doi:10.1161/01.res.81.5.643. PMID 9351436. Yang Z, Sun W, Hu K (Apr 2012). "Molecular ... "Cardioprotection with kappa-opioid receptor stimulation is associated with a slowing of cross-bridge cycling". American Journal ... Circulation Research. 74 (2): 299-309. doi:10.1161/01.res.74.2.299. PMID 8293569. Disatnik MH, Buraggi G, Mochly-Rosen D (Feb ... Circulation Research. 88 (1): 59-62. doi:10.1161/01.res.88.1.59. PMID 11139474. Jideama NM, Noland TA, Raynor RL, Blobe GC, ...
Shortly after her book was published, Peters traveled to Bosnia where she served with the Red Cross. When she returned to the ... Her book remains in circulation. Jou, Chin (2007-10-11). "Your Stomach Must Be Disciplined": Lulu Hunt Peters and the ...
"Cross platform circulation certificate" (PDF). Audit Bureau of Circulation. Retrieved 7 May 2013. "Judge critiques". The Kennel ... Dog World has traditionally published a wide cross section of opinion and has often taken issue with the Kennel Club (KC). ... The Audit Bureau records a 98.8 per cent purchased average circulation figure of 11,700 print copies each week throughout 2012 ...
Labor Notes is the largest circulation cross-union publication remaining in the United States. It reports news and analysis ... a b c Cross Currents. Labor unions in Japan. CULCON. Retrieved 11 June 2011 ... Unions may organize a particular section of skilled workers (craft unionism),[3] a cross-section of workers from various trades ... a cross-section of workers from various trades (general unionism, traditionally found in Australia, Belgium, Canada, Denmark, ...
The circulation of De Tijd was 59,144 copies and its market share was 4.7% in 2002. The circulation of the paper was 39,315 ... 2014). "Does Media Cross-Ownership Translate into Cross-Promotion?". Journalism Studies. doi:10.1080/1461670X.2014.953780. ... "National newspapers total circulation". International Federation of Audit Bureaux of Circulations. Retrieved 3 December 2014. ... It was 37,448 copies in 2010, 39,431 copies in 2011 and a total circulation of 41.065 (digital+print) in 2015. According to the ...
Scheme of placental circulation. Human embryo with heart and anterior body-wall removed to show the sinus venosus and its ... Deep dissection.Serial cross section. Umbilical line [1] The Umbilical Cord Meyer WW, Rumpelt HJ, Yao AC, Lind J (July 1978). " ... As the umbilical vein is directly connected to the central circulation, it can be used as a route for placement of a venous ... "improved transitional circulation, better establishment of red blood cell volume, and decreased need for blood transfusion". In ...
A clinical-radiological correlation study". Stroke: A Journal of Cerebral Circulation. 26 (6): 950-5. doi:10.1161/01.STR.26.6. ... Krasnianski, M; Neudecker, S; Zierz, S (Aug 2004). "[Classical crossed pontine syndromes]". Fortschritte der Neurologie · ... "The crossed paralyses. The original brain-stem syndromes of Millard-Gubler, Foville, Weber, and Raymond-Cestan". Archives of ...
The Daily Southern Cross was first published in 1843 by William Brown as The Southern Cross and had been a daily since 1862. ... although circulation of the daily Herald had declined to 144,157 copies on average by December 2014. Its main circulation area ... "The Daily Southern Cross". National Library of New Zealand - Te Puna Mātauranga o Aotearoa. Retrieved 30 October 2012. "New ... "The Daily Southern Cross". National Library of New Zealand - Te Puna Mātauranga o Aotearoa. Retrieved 30 October 2012. "Daily ...
... the absence of blood circulation (and vital functions related to blood circulation) was historically considered the official ... "Effect of extended cross-clamp time during thoracoabdominal aortic aneurysm repair". The Annals of Thoracic Surgery. The ... Blood circulation can be stopped in the entire body below the heart for at least 30 minutes, with injury to the spinal cord ... Stopped blood circulation has historically proven irreversible in most cases. Prior to the invention of cardiopulmonary ...
In 2007 the circulation of Buffé was 1,996,900 copies, making it the best-selling magazine in Sweden. The circulation was ... Mikael Vemmenby (2011). "How Cross Media is used by ICA Supermarket to improve their Brand" (PDF). CHI. Retrieved 6 February ...
A ventricular assist device (VAD) is an electromechanical device for assisting cardiac circulation, which is used either to ... 2014). "Educational resources for patients considering a left ventricular assist device: a cross-sectional review of internet, ... Kirklin, JK; Naftel, DC (September 2008). "Mechanical circulatory support: registering a therapy in evolution". Circulation: ... might be necessary to resolve the problem of cardiac circulation. If both a LVAD and a RVAD is needed a BiVAD is normally used ...
Its circulation totals over six million readers. "eCirc for Consumer Magazines". Audit Bureau of Circulations. June 30, 2011. ... It occasionally features cover stories on celebrities such as Marcia Cross and Elisabeth Röhm and tips from Bethenny Frankel, a ...
Its circulation is 2,000 per week. UIS athletic teams are known as the Prairie Stars, and compete in the NCAA Division II's ... cross country, cheerleading, golf, soccer, softball, tennis, track & field and volleyball; men's sports include baseball, ...
It was initially disorganized, without a well-developed circulation. On September 25, while still a tropical depression, the ... Without intensifying further, the depression crossed the northeastern Yucatán Peninsula on September 26. The next day, the ... On September 30, the circulation of Debbie dissipated just offshore Mississippi. Its remnants made landfall, accelerated ...
The Battle Cross. A Romance of the Fourteenth Century, 3 vols 12mo, London, 1845. Ellie Forestere, a novel, 3 vols. 12mo, ... Sunbeams and Shadows, poems, printed for private circulation, 1853. Village Bells, Lady Gwendoline, and other Poems, 8vo London ...
"Circulation. doi:10.1161/CIRCULATIONAHA.114.014542.. *^ a b Davis, Robert (July 28, 2003). "Special report: Many lives are lost ... Andrew's First Aid; British Red Cross Society.. *^ Ali S, Athar M, Ahmed SM. A randomised controlled comparison of video versus ... "Circulation. 133 (4): e38-e360. doi:10.1161/CIR.0000000000000350.. *^ Go, Alan S.; Mozaffarian, Dariush; Roger, Véronique L.; ... "Circulation. 139 (10): e56-e528. doi:10.1161/CIR.0000000000000659.. *^ Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, ...
4m high wooden cross and a religious artwork Credo. The church is a center for the evangelical believers from the fourth ... Circulation is approximately 16,000 issues. Dúbravská televízia - Established in 1999, the local TV station broadcasts 24-hours ...
Plane light above, cross-polarized light below. Scale box is 0.25 mm. ... the process by which hydrothermal circulation cracks and brecciates the wall rocks and fills it in with veins. This is ...
DPH has over 4 million prints in circulation to date. Through Oyedepo Covenant University, Faith Academy and Kingdom Heritage ... The construction of a third university named Crown University is already underway, located in Calabar, Cross Rivers, Nigeria ...
... *Download PDF Copy ... A previous study from the team demonstrated a cross-circulation platform that maintained the viability and function of a donor ... We envision that interventional cross-circulation may be used to investigate regeneration of other damaged organs, such as ... In a study published today on Nature Communications website, the researchers describe the cross-circulation platform that ...
tags: cross circulation x microbiology x The Scientist. » cross circulation and microbiology ...
Cross-Reactivity of Anti-CagA Antibodies With Vascular Wall Antigens. Francesco Franceschi, Antonia R. Sepulveda, Antonio ... Cross-Reactivity of Anti-CagA Antibodies With Vascular Wall Antigens. Francesco Franceschi, Antonia R. Sepulveda, Antonio ... Cross-Reactivity of Anti-CagA Antibodies With Vascular Wall Antigens. Possible Pathogenic Link Between Helicobacter pylori ... Second, there was no evidence, until now, of H pyloris ability to spread from its gastric niche via the blood circulation. ...
Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person ... Two cases are described in which the systemic and pulmonary blood streams cross at atrioventricular level. One was examined ... Criss-Cross Atrioventricular Relationships Producing Paradoxical Atrioventricular Concordance or Discordance. ROBERT H. ... Criss-Cross Atrioventricular Relationships Producing Paradoxical Atrioventricular Concordance or Discordance. ROBERT H. ...
Blue Cross Blue Shield of Massachusetts is an Independent Licensee of the Blue Cross and Blue Shield Association.. ® Registered ... Blood circulation after birth. The closure of the ductus arteriosus, ductus venosus, and foramen ovale completes the change of ... About Blue Cross Blue Shield of Massachusetts Terms of Use, Privacy & Security Accessibility Nondiscrimination and Translation ... Blue Cross Blue Shield of Massachusetts is a leading provider of quality health insurance for residents of Massachusetts. Our ...
... the Fontan anastomosis has been thought to reflect flow efficiencies and to influence on hemodynamics in the Fontan circulation ... Quantitative Evaluation of Hemodynamics in the Fontan Circulation: A Cross-Sectional Study Measuring Energy Loss In Vivo. ... Q was calculated as the product of velocity and the cross-sectional area of the vessel lumen. The cross-sectional areas of the ... In the Fontan circulation, it is possible that EL itself can be an afterload in a serial circulation and can cause workload for ...
Cross Talk Pathways Between Coagulation and Inflammation. Jonathan H. Foley, Edward M. Conway ... Your Name) thought you would like to see the Circulation Research web site. ... Thank you for your interest in spreading the word on Circulation Research. ...
COX-2, Another Important Player in the Nitric Oxide-Endothelin Cross-Talk. Good News for COX-2 Inhibitors?. Ulrich Hink, Thomas ... In this issue of Circulation Research, Zhou et al15 examined to what extent chronic NO deficiency may alter ETA mediated ... Intravascular thrombosis after hypoxia-induced pulmonary hypertension: regulation by cyclooxygenase-2. Circulation. 2004; 110: ... Your Name) thought you would like to see the Circulation Research web site. ...
A handling method for a natural circulation boiling water reactor having a chimney having cylindrical chimney shell disposed ... 2c shows a cross-section taken along a line Y-Y in FIG. 2a. However, in FIGS. 2a-2c the chimney shell is omitted for the sake ... After outlines of the natural circulation boiling water reactor are described, the chimney included in the natural circulation ... 8b, the flow path partition walls 211b form grids in the cross sectional view and the flow paths 211a form a square shape. The ...
... but the complexity of circulation in those seasons needs to be resolved to confirm the strength of this connection. Our results ... strongly suggest cross-boundary coordination is essential in the conservation of deep-water corals in the northwest Atlantic, ... Regional Ocean Circulation. Ocean circulation at the shelf edge of the Gulf of Maine is influenced in part by regional ... circulation is dominated by strong M2 tidal currents (semidiurnal) coupled with an anticyclonic residual circulation with ...
11/15/2018 Blood, Heart and Circulation A protein central to immune system function is a new target for treating pulmonary ... However, the study found no association between the years of training in cross-country skiing (an average of 36 years in this ... 1. Grimsmo J, Grundvold I, Maehlum S, Arnesen H. High prevalence of atrial fibrillation in long-term endurance cross-country ... A high prevalence of atrial fibrillation found among highly trained cross-country skiers taking part in Norways annual ...
Circulation. 2017;135:e146-603. https://doi.org/10.1161/cir.0000000000000485.CrossRefPubMedPubMedCentralGoogle Scholar ... Fifty-four healthy, non-smoking men and women aged 18-50 years were included in this cross-sectional sub-study of a randomized ... Although no causal relationship can be made due to the cross-sectional design of the study, the current study shows that the ... Plasma n-6 and n-3 polyunsaturated fatty acids as biomarkers of their dietary intakes: a cross-sectional study within a cohort ...
In this cross-sectional study we took advantage of the natural experimental conditions resulting from the variable fasting ... The major limitation of our research was that all analyses were conducted across a large sample and on a cross-sectional basis ... Fasting Might Not Be Necessary Before Lipid Screening: A Nationally Representative Cross-sectional Study. Michael J. Steiner, ... Comparing a nationally representative cross-section of children who had fasted for various lengths of time, we demonstrated ...
Design: Cross sectional study using multivariate regression models to examine the relation between clinical variables and left ... Cross sectional study of contribution of clinical assessment and simple cardiac investigations to diagnosis of left ventricular ... This study is a substudy of a cross-sectional survey that aimed to determine the prevalence of heart failure in general ... Suspected cases were identified within the cross sectional study population by reviewing all general practice case notes and ...
Circulation2011;124:2365-74.. OpenUrlFREE Full Text. *↵. Spertus JA, Winder JA, Dewhurst TA, Deyo RA, Prodzinski J, McDonell M ... This cross sectional study was an extension of the Personalized Risk Information Services Manager (PRISM) study (NCT01383382), ... Design Cross sectional study.. Setting 10 US academic and community hospitals performing percutaneous coronary interventions ... Variation in patients perceptions of elective percutaneous coronary intervention in stable coronary artery disease: cross ...
"Circulation. 116: 443. Archived from the original on 15 October 2015.. *^ Loria V, Dato I, Graziani F, Biasucci LM (2008). " ... "Southern Cross Healthcare Group. Archived from the original on 3 March 2014. Retrieved 15 September 2013.. ... "Circulation. 102 (10): 1082-85. doi:10.1161/01.CIR.102.10.1082. PMID 10973834. Archived from the original on 5 July 2011.. ... "Circulation: Cardiovascular Quality and Outcomes. 9 (3): 257-264. doi:10.1161/CIRCOUTCOMES.115.002224. PMC 4940126 . PMID ...
American Red Cross. First Aid/CPR/AED Participants Manual. 2nd ed. Dallas, TX: American Red Cross; 2016. ... Circulation. 2015;132(18 Suppl 2):S519-S525. PMID: 26472999 www.ncbi.nlm.nih.gov/pubmed/26472999. ... Circulation. 2015;132(18 Suppl 2):S414-S435. PMID: 26472993 www.ncbi.nlm.nih.gov/pubmed/26472993. ...
Cross Circulation Succeeds August 18, 1951 by Science News * Feature Cortisone for Asthma ...
Green Cross Corp. Stable emulsion of fluorocarbon particles. US3894541 *. 27 Feb 1974. 15 Jul 1975. El Shafei Ismail Lotfy. ... and circulation monitoring means for insuring that desired circulation flows and pressures are maintained within the system. ... Zoll Circulation, Inc.. System and method for management of body temperature. US20040039431 *. 20 Aug 2003. 26 Feb 2004. ... The circulation route illustrated in FIG. 1 permits the treatment of at least cerebral tissues. It is within the scope of the ...
On-site bus circulation; buses cross each other • Requires acquisition and relocation of 3 properties (including gas station ... of Relocations = 1 Fast Auto Loans BUS ACCESS/CIRCULATION Proposed Intersection Improvements Improved Pedestrian Access On-site ... On-site Bus Circulation • Cost Effectiveness • Amenities • Bus Access • Traffic • Intermodality • Neighborhood Development • ... Efficient on-site bus circulation; loop design • High potential for future neighborhood development • Adjacent to busy ...
Circulation 111:1448-1454, 2005. OpenUrlFREE Full Text. *↵ Cefalu WT: Concept, strategies, and feasibility of noninvasive ... Cross-sectional analyses. As shown in Table 2, compared with their nondiabetic counterparts, in the models adjusting for age, ... In cross-sectional analyses, middle-aged adults with type 2 diabetes had significantly lower FVC, FEV1, FVC % predicted, and ... Cross-Sectional and Prospective Study of Lung Function in Adults With Type 2 Diabetes. The Atherosclerosis Risk in Communities ...
Circulation 2007;115:2111-2118pmid:17420343. OpenUrlAbstract/FREE Full Text ... This cross-sectional study used baseline data from UK Biobank, a large, population-based cohort study set up to study the ... Previous U.K. cross-sectional studies have been smaller overall, recruited smaller numbers of nonwhite participants, and ... 10) pooled data from 30 cross-sectional studies (n = 54,467), conducted in 11 Asian and European countries, on the crude ...
Circulation 2008;117(6):743-53. CrossRefexternal icon PubMedexternal icon ... KNHANES has a cross-sectional design, and, therefore, we cannot infer causality. Reverse causality is theoretically possible, ... Study Title: Cumulative Social Risk and Cardiovascular Disease Among Adults in South Korea: A Cross-Sectional Analysis of a ... Cumulative Social Risk and Cardiovascular Disease Among Adults in South Korea: A Cross-Sectional Analysis of a Nationally ...
  • RESEARCH DESIGN AND METHODS -We conducted cross-sectional and prospective analyses of diabetes status and lung function decline using baseline and 3-year follow-up data on 1,100 diabetic and 10,162 nondiabetic middle-aged adults from the Atherosclerosis Risk in Communities (ARIC) Study. (diabetesjournals.org)
  • Evaluation of human coronary blood flow with an 80 channel 20 MHz pulsed Doppler velocimeter and zero-cross and Fourier transform methods during cardiac surgery. (biomedsearch.com)
  • Methods The authors applied a parallel and statistically integrated bacterial profiling and metabonomic approach to characterise Roux-en-Y gastric bypass (RYGB) effects in a non-obese rat model. (bmj.com)
  • Background and Purpose -The cross-sectional and 4-year longitudinal associations between brachial pulse pressure (PP) and ultrasound measurements of common carotid intima-media thickness (CCA-IMT) were assessed. (ahajournals.org)
  • Longitudinal studies are thus necessary to confirm and extend the cross-sectional findings and indicate the possible direction of the relationships. (ahajournals.org)
  • By contrast, only a single morbidity outcome in cross-sectional and none in longitudinal analysis was predicted by low T/normal cFT (LN) or normal T/low cFT (NL) without significant LL associations (isolated discordance). (deepdyve.com)
  • At the sites of the RCA aneurysms, intravascular ultrasound demonstrated large areas of late acquired stent malapposition (LSM) due to vessel remodeling (an increase in cross-sectional and longitudinal vessel dimensions), changes that were most marked at the sites of subintimal stent implantation ( Fig. 2 ). (onlinejacc.org)
  • The newly formed gap between previously overlapped stents suggested that positive vessel remodeling occurred in the longitudinal direction as well as cross-sectionally. (onlinejacc.org)
  • Staywell®´´, an independent company, offers health and wellness engagement tools and information on behalf of Blue Cross Blue Shield of Massachusetts. (ahealthyme.com)
  • Blue Cross Blue Shield of Massachusetts is a leading provider of quality health insurance for residents of Massachusetts. (ahealthyme.com)
  • Blue Cross Blue Shield of Nebraska has launched a new health insurance option for individuals and families in the state. (omaha.com)
  • Boehringer Ingelheim has announced that the combined treatment experience with Pradaxa® has crossed one million patient-years(1) in the prevention of thromboembolic events in patients after surgery and in patients with non-valvular atrial fibrillation (AF), providing the greatest body of clinical experience among all novel oral anticoagulants. (worldpharmanews.com)
  • Our results strongly suggest that cross-boundary coordination is essential in the conservation of aggregations of deep-water corals in the northwest Atlantic, by ensuring larval exchange and connectivity. (frontiersin.org)
  • Results offer the most comprehensive cross-national demonstration of negativity biases to date, but they also serve to highlight considerable individual-level variation in responsiveness to news content. (pnas.org)
  • Paradoxically, CD3 cross-linking prior to TCR stimulation results in apoptotic cell death, as does injection of anti-CD4 antibodies in vivo of CD4 ligation by HIV glycoprotein (gp) 120. (pnas.org)
  • We have found that CD4 cross-linking results in a small but rapid increase in levels of cell surface Fas, a member of the tumor necrosis factor receptor family implicated in apoptotic death and maintenance of immune homeostasis. (pnas.org)
  • CONCLUSIONS These results identify a novel antagonistic cross-talk between IFN-γ and Hh signaling in white adipose tissue and demonstrate IFN-γ as a potent inhibitor of Hh signaling. (diabetesjournals.org)
  • 8 9 10 However, cross-sectional results do not allow determination of the direction and time-dependent relationships. (ahajournals.org)
  • Co-circulation of multiple avian influenza viruses that can infect humans highlights the need for increased surveillance of poultry and potential environmental sources. (cdc.gov)
  • A method and drilling fluid additive composition are provided for reducing lost circulation and seepage loss when synthetic or oil based drilling fluid is used. (google.com)
  • 6 . A lost circulation drilling fluid additive for use with synthetic or oil based drilling fluids comprising 20 to 80 parts by weight fibrous particles, 10 to 40 parts by weight lignite, and 10 to 40 parts by weight phenol-formaldehyde resin solids. (google.com)
  • Several cross-sectional epidemiological studies have shown positive but moderate associations between brachial PP and ultrasound measurements of common carotid intima-media thickness (CCA-IMT), 5 6 7 8 an early marker of atherosclerosis and/or vascular remodeling. (ahajournals.org)
  • Through adoptive cell transfers and cross-breeding to hypercholesterolemic mice expressing the antigenic human LDL protein apolipoprotein B-100, we evaluate the effects on atherosclerosis. (nih.gov)
  • Ex Vivo Heart Perfusion for 72 Hours Using Plasma Cross Circulation. (nih.gov)
  • In this report we investigate the mechanism by which CD4 cross-linking induces cell death. (pnas.org)
  • Different with the producer price, the market price of means of production includes producer price, as well as the circulation expenses, profits and taxes of the enterprises. (stats.gov.cn)
  • 14, 1980, entitled "Extravascular Circulation Oxygenated Synthetic Nutrients to Treat Tissue Hypoxic and Ischemic Disorders", now U.S. Pat. (google.co.uk)
  • Flow energy loss (EL) at the Fontan anastomosis has been thought to reflect flow efficiencies and to influence on hemodynamics in the Fontan circulation and has been often discussed in numerical studies. (springer.com)
  • In light of recent findings in neurons that IFN-γ and Hh signaling cross-talk, we examined their potential interaction in the context of adipogenesis. (diabetesjournals.org)
  • The effect of RYGB surgery on the host metabolic-microbial cross-talk augments our understanding of the metabolic phenotype of bariatric procedures and can facilitate enhanced treatments for obesity-related diseases. (bmj.com)
  • Sequence analysis showed co-circulation of 4 influenza A(H7N9) virus strains that evolved by reassortment with avian influenza A(H9N2) viruses circulating in this region. (cdc.gov)
  • consequently, data linking directly measured insulin resistance with CVD is derived mostly from cross-sectional studies ( 10 ) and rarely from prospective cohorts ( 11 , 12 ). (diabetesjournals.org)
  • We envision that interventional cross-circulation may be used to investigate regeneration of other damaged organs, such as hearts, kidneys, and livers, expanding donor pools by salvaging severely damaged organs and leading to more organ transplants,' Bacchetta adds. (news-medical.net)
  • Although cross-sectional data are available through national surveys, data on alcohol consumption in Alberta from a large prospective cohort were not previously available. (canada.ca)
  • Unions may organize a particular section of skilled workers ( craft unionism ), a cross-section of workers from various trades ( general unionism ), or attempt to organize all workers within a particular industry ( industrial unionism ). (wikipedia.org)
  • Design Data from two nationally-representative cross-sectional surveys undertaken in 2013-2014. (bmj.com)
  • The cross-sectional design cannot realise an investigation of the causal pathway of the association between the ACE genotype and salt intake interaction with hypertension, although possible mechanisms were suggested for the interaction effect on hypertension. (bmj.com)
  • Many Holy Cross staffers and those from other facilities commented on the attractive design and asked to be considered for transfer or employment. (healthcaredesignmagazine.com)
  • The present invention relates to a natural circulation boiling water reactor and a handling method thereof. (freepatentsonline.com)
  • Doppler signals from 80 channels are detected by a zero-cross method and a signal from an optional channel is analyzed by a fast-Fourier transform method, both in real time. (biomedsearch.com)
  • From comparisons of aerodynamic impulse derived from our circulation analysis with the impulse estimated from whole-body acceleration, it appeared that our quasi-steady aerodynamic analysis was most accurate at intermediate speeds (5-11 ms -1 ). (biologists.org)
  • The chimney has a function for promoting natural circulation of the coolant in the reactor pressure vessel by introducing the coolant which is two-phase flow including gas and liquid and is exhausted from a core, to an upper portion in the reactor pressure vessel. (freepatentsonline.com)
  • Importantly, CD4 cross-linking triggered the ability of Fas to function as a death molecule. (pnas.org)
  • Individual policies in Nebraska are far too expensive, especially for those who utilize little to moderate care," Dale Mackel, Blue Cross executive vice president, said in a statement. (omaha.com)
  • In this issue of Circulation Research , Zhou et al 15 examined to what extent chronic NO deficiency may alter ET A mediated vasoconstriction and the involvement of vasoconstricting prostanoids. (ahajournals.org)