GreeceDolphins: Mammals of the families Delphinidae (ocean dolphins), Iniidae, Lipotidae, Pontoporiidae, and Platanistidae (all river dolphins). Among the most well-known species are the BOTTLE-NOSED DOLPHIN and the KILLER WHALE (a dolphin). The common name dolphin is applied to small cetaceans having a beaklike snout and a slender, streamlined body, whereas PORPOISES are small cetaceans with a blunt snout and rather stocky body. (From Walker's Mammals of the World, 5th ed, pp978-9)Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Cetacea: An order of wholly aquatic MAMMALS occurring in all the OCEANS and adjoining seas of the world, as well as in certain river systems. They feed generally on FISHES, cephalopods, and crustaceans. Most are gregarious and most have a relatively long period of parental care and maturation. Included are DOLPHINS; PORPOISES; and WHALES. (From Walker's Mammals of the World, 5th ed, pp969-70)Porpoises: Mammals of the family Phocoenidae comprising four genera found in the North Pacific Ocean and both sides of the North Atlantic Ocean and in various other seas. They differ from DOLPHINS in that porpoises have a blunt snout and a rather stocky body while dolphins have a beak-like snout and a slender, streamlined body. They usually travel in small groups. (From Walker's Mammals of the World, 5th ed, pp1003-4)Bottle-Nosed Dolphin: The species Tursiops truncatus, in the family Delphinidae, characterized by a bottle-shaped beak and slightly hooked broad dorsal fin.Whales: Large marine mammals of the order CETACEA. In the past, they were commercially valued for whale oil, for their flesh as human food and in ANIMAL FEED and FERTILIZERS, and for baleen. Today, there is a moratorium on most commercial whaling, as all species are either listed as endangered or threatened.Phocoena: A genus of PORPOISES, in the family Phocoenidae, comprised of several species. They frequent coastal waters, bays, estuaries, and the mouths of large rivers.Water Pollutants, Chemical: Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water.Forelimb: A front limb of a quadruped. (The Random House College Dictionary, 1980)Scandentia: An order of the class MAMMALS that consists of one family, TUPAIIDAE (tree shrews), 5 genera (one of which is TUPAIA), and 16 species. Their recent distribution is from India to the Philippines, southern China to Java, Borneo, Sumatra, Bali, and other islands in those regions.Insectivora: An order of insect eating MAMMALS including MOLES; SHREWS; HEDGEHOGS and tenrecs.Streptomyces griseus: An actinomycete from which the antibiotics STREPTOMYCIN, grisein, and CANDICIDIN are obtained.Methyl n-Butyl Ketone: An industrial solvent which causes nervous system degeneration. MBK is an acronym often used to refer to it.Lagomorpha: An order of small mammals comprising two families, Ochotonidae (pikas) and Leporidae (RABBITS and HARES). Head and body length ranges from about 125 mm to 750 mm. Hares and rabbits have a short tail, and the pikas lack a tail. Rabbits are born furless and with both eyes and ears closed. HARES are born fully haired with eyes and ears open. All are vegetarians. (From Nowak, Walker's Mammals of the World, 5th ed, p539-41)Sodium Channels: Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.Chordata: Phylum in the domain Eukarya, comprised of animals either with fully developed backbones (VERTEBRATES), or those with notochords only during some developmental stage (CHORDATA, NONVERTEBRATE).Rodentia: A mammalian order which consists of 29 families and many genera.Enoplida Infections: Infections with nematodes of the order ENOPLIDA.Amoeba: A genus of ameboid protozoa. Characteristics include a vesicular nucleus and the formation of several lodopodia, one of which is dominant at a given time. Reproduction occurs asexually by binary fission.TRPV Cation Channels: A subgroup of TRP cation channels named after vanilloid receptor. They are very sensitive to TEMPERATURE and hot spicy food and CAPSAICIN. They have the TRP domain and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold.Receptor, Melatonin, MT2: A melatonin receptor subtype primarily found expressed in the BRAIN and RETINA.Isoindoles: Benzopyrroles with the nitrogen at the number two carbon, in contrast to INDOLES which have the nitrogen adjacent to the six-membered ring.WyomingPhylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Liliaceae: A monocot family within the order Liliales. This family is divided by some botanists into other families such as Convallariaceae, Hyacinthaceae and Amaryllidaceae. Amaryllidaceae, which have inferior ovaries, includes CRINUM; GALANTHUS; LYCORIS; and NARCISSUS and are known for AMARYLLIDACEAE ALKALOIDS.Orchidaceae: A plant family of the order Orchidales, subclass Liliidae, class Liliopsida (monocotyledons). All orchids have the same bilaterally symmetrical flower structure, with three sepals, but the flowers vary greatly in color and shape.Likelihood Functions: Functions constructed from a statistical model and a set of observed data which give the probability of that data for various values of the unknown model parameters. Those parameter values that maximize the probability are the maximum likelihood estimates of the parameters.Yin-Yang: In Chinese philosophy and religion, two principles, one negative, dark, and feminine (yin) and one positive, bright, and masculine (yang), from whose interaction all things are produced and all things are dissolved. As a concept the two polar elements referred originally to the shady and sunny sides of a valley or a hill but it developed into the relationship of any contrasting pair: those specified above (female-male, etc.) as well as cold-hot, wet-dry, weak-strong, etc. It is not a distinct system of thought by itself but permeates Chinese life and thought. A balance of yin and yang is essential to health. A deficiency of either principle can manifest as disease. (Encyclopedia Americana)

Fitzgerald factor (high molecular weight kininogen) clotting activity in human plasma in health and disease in various animal plasmas. (1/32376)

Fitzgerald factor (high molecular weight kininogen) is an agent in normal human plasma that corrects the impaired in vitro surface-mediated plasma reactions of blood coagulation, fibrinolysis, and kinin generation observed in Fitzgerald trait plasma. To assess the possible pathophysiologic role of Fitzgerald factor, its titer was measured by a functional clot-promoting assay. Mean +/- SD in 42 normal adults was 0.99+/-0.25 units/ml, one unit being the activity in 1 ml of normal pooled plasma. No difference in titer was noted between normal men and women, during pregnancy, or after physical exercise. Fitzgerald factor activity was significantly reduced in the plasmas of eight patients with advanced hepatic cirrhosis (0.40+/-0.09 units/ml) and of ten patients with disseminated intravascular coagulation (0.60+/-0.30 units/ml), but was normal in plasmas of patients with other congenital clotting factor deficiencies, nephrotic syndrome, rheumatoid arthritis, systemic lupus erythematosus, or sarcoidosis, or under treatment with warfarin. The plasmas of 21 mammalian species tested appeared to contain Fitzgerald factor activity, but those of two avian, two repitilian, and one amphibian species did not correct the coagulant defect in Fitzgerald trait plasmas.  (+info)

Differences in benzo(a)pyrene metabolism between rodent liver microsomes and embryonic cells. (2/32376)

Differences in benzo(a)pyrene metabolite pattern have been shown by rodent liver microsomes (Sprague-Dawley) and rodent embryo cells from Syrian hamsters and NIH Swiss mice. Rodent liver induced by methylcholanthrene shows marked quantitative variation between species. Additional pattern changes were found in mouse and hamster embryo secondary cultures with a reduction of the K-region metabolites and a marked increase in 9-hydroxybenzo(a)-pyrene. These results are indicative of a region-specific attack on the carcinogen by the cell monooxygenases which is distinct from the liver attack of microsomal enzymes on benzo(a)pyrene. These results suggest that activation and detoxification of benzo(a)pyrene may be species and tissue variable, and susceptibility and resistence to malignant transformation may be predicted on induction of a fortuitous combination of intermediate metabolic steps.  (+info)

Ambiguity of the thymidine index. (3/32376)

The observed thymidine indices of seven experimental tumor lines are compared as a function of duration of emulsion exposure. The effects of dose level of tritiated thymidine and background threshold are also evaluated. The results indicate that an arbitrary high background threshold discriminates against "lightly" labeled cells at short periods of exposure but that the chosen threshold becomes less critical with longer exposure. The observed thymidine index increases with increasing duration of emulsion exposure but appears to approach a plateau for all tumor systems. The "thymidine index curves" are significantly different for each tumor. There is an inverse relationship between the dose of tritiated thymidine and the duration of exposure required to recognize the same fraction of cells as labeled in a given tumor. Similar experimental conditions do not necessarily guarantee a valid basis for comparison of observed thymidine indices among tumors.  (+info)

Morphogenesis of callosal arbors in the parietal cortex of hamsters. (4/32376)

The morphogenesis of callosal axons originating in the parietal cortex was studied by anterograde labeling with Phaseolus lectin or biocytin injected in postnatal (P) hamsters aged 7-25 days. Some labeled fibers were serially reconstructed. At P7, some callosal fibers extended as far as the contralateral rhinal fissure, with simple arbors located in the homotopic region of the opposite cortical gray matter, and two or three unbranched sprouts along their trajectory. From P7 to P13, the homotopic arbors became more complex, with branches focused predominantly, but not exclusively, in the supra- and infragranular layers of the homotopic region. Simultaneously, the lateral extension of the trunk axon in the white matter became shorter, finally disappearing by P25. Arbors in the gray matter were either bilaminar (layers 2/3 and 5) or supragranular. A heterotopic projection to the lateral cortex was consistently seen at all ages; the heterotopic arbors follow a similar sequence of events to that seen in homotopic regions. These observations document that callosal axons undergo regressive tangential remodeling during the first postnatal month, as the lateral extension of the trunk fiber gets eliminated. Radially, however, significant arborization occurs in layer-specific locations. The protracted period of morphogenesis suggests a correspondingly long plastic period for this system of cortical fibers.  (+info)

A premature termination codon interferes with the nuclear function of an exon splicing enhancer in an open reading frame-dependent manner. (5/32376)

Premature translation termination codon (PTC)-mediated effects on nuclear RNA processing have been shown to be associated with a number of human genetic diseases; however, how these PTCs mediate such effects in the nucleus is unclear. A PTC at nucleotide (nt) 2018 that lies adjacent to the 5' element of a bipartite exon splicing enhancer within the NS2-specific exon of minute virus of mice P4 promoter-generated pre-mRNA caused a decrease in the accumulated levels of P4-generated R2 mRNA relative to P4-generated R1 mRNA, although the total accumulated levels of P4 product remained the same. This effect was seen in nuclear RNA and was independent of RNA stability. The 5' and 3' elements of the bipartite NS2-specific exon enhancer are redundant in function, and when the 2018 PTC was combined with a deletion of the 3' enhancer element, the exon was skipped in the majority of the viral P4-generated product. Such exon skipping in response to a PTC, but not a missense mutation at nt 2018, could be suppressed by frame shift mutations in either exon of NS2 which reopened the NS2 open reading frame, as well as by improvement of the upstream intron 3' splice site. These results suggest that a PTC can interfere with the function of an exon splicing enhancer in an open reading frame-dependent manner and that the PTC is recognized in the nucleus.  (+info)

In vivo chaperone activity of heat shock protein 70 and thermotolerance. (6/32376)

Heat shock protein 70 (Hsp70) is thought to play a critical role in the thermotolerance of mammalian cells, presumably due to its chaperone activity. We examined the chaperone activity and cellular heat resistance of a clonal cell line in which overexpression of Hsp70 was transiently induced by means of the tetracycline-regulated gene expression system. This single-cell-line approach circumvents problems associated with clonal variation and indirect effects resulting from constitutive overexpression of Hsp70. The in vivo chaperone function of Hsp70 was quantitatively investigated by using firefly luciferase as a reporter protein. Chaperone activity was found to strictly correlate to the level of Hsp70 expression. In addition, we observed an Hsp70 concentration dependent increase in the cellular heat resistance. In order to study the contribution of the Hsp70 chaperone activity, heat resistance of cells that expressed tetracycline-regulated Hsp70 was compared to thermotolerant cells expressing the same level of Hsp70 plus all of the other heat shock proteins. Overexpression of Hsp70 alone was sufficient to induce a similar recovery of cytoplasmic luciferase activity, as does expression of all Hsps in thermotolerant cells. However, when the luciferase reporter protein was directed to the nucleus, expression of Hsp70 alone was not sufficient to yield the level of recovery observed in thermotolerant cells. In addition, cells expressing the same level of Hsp70 found in heat-induced thermotolerant cells containing additional Hsps showed increased resistance to thermal killing but were more sensitive than thermotolerant cells. These results suggest that the inducible form of Hsp70 contributes to the stress-tolerant state by increasing the chaperone activity in the cytoplasm. However, its expression alone is apparently insufficient for protection of other subcellular compartments to yield clonal heat resistance to the level observed in thermotolerant cells.  (+info)

Requirement for transcription factor NFAT in interleukin-2 expression. (7/32376)

The nuclear factor of activated T cells (NFAT) transcription factor is implicated in expression of the cytokine interleukin-2 (IL-2). Binding sites for NFAT are located in the IL-2 promoter. Furthermore, pharmacological studies demonstrate that the drug cyclosporin A inhibits both NFAT activation and IL-2 expression. However, targeted disruption of the NFAT1 and NFAT2 genes in mice does not cause decreased IL-2 secretion. The role of NFAT in IL-2 gene expression is therefore unclear. Here we report the construction of a dominant-negative NFAT mutant (dnNFAT) that selectively inhibits NFAT-mediated gene expression. The inhibitory effect of dnNFAT is mediated by suppression of activation-induced nuclear translocation of NFAT. Expression of dnNFAT in cultured T cells caused inhibition of IL-2 promoter activity and decreased expression of IL-2 protein. Similarly, expression of dnNFAT in transgenic mice also caused decreased IL-2 gene expression. These data demonstrate that NFAT is a critical component of the signaling pathway that regulates IL-2 expression.  (+info)

Isolation of human transcripts expressed in hamster cells from YACs by cDNA representational difference analysis. (8/32376)

Gene isolation methods used during positional cloning rely on physical contigs consisting of bacterial artificial chromosomes, P1, or cosmid clones. However, in most instances, the initial framework for physical mapping consists of contigs of yeast artificial chromosome (YACs), large vectors that are suboptimal substrates for gene isolation. Here we report a strategy to identify gene sequences contained within a YAC by using cDNA representational difference analysis (RDA) to directly isolate transcripts expressed from the YAC in mammalian cells. The RDA tester cDNAs were generated from a previously reported hamster cell line derived by stable transfer of a 590-kb YAC (911D5) that expressed NPC1, the human gene responsible for Niemann-Pick type C (NP-C). The driver cDNAs were generated from a control hamster cell line that did not contain the YAC that expressed NPC1. Among the gene fragments obtained by RDA, NPC1 was the most abundant product. In addition, two non-NPC1 fragments were isolated that were mapped to and expressed from 911D5. One of these RDA gene fragments (7-R) spans more than one exon and has 98% sequence identity with a human cDNA clone reported previously as an expressed sequence tag (EST), but not mapped to a chromosomal region. The other fragment (2-R) that had no significant sequence similarities with known mammalian genes or ESTs, was further localized to the region of overlap between YACs 911D5 and 844E3. The latter YAC is part of a contig across the NP-C candidate region, but does not contain NPC1. This two-part approach in which stable YAC transfer is followed by cDNA RDA should be a useful adjunct strategy to expedite the cloning of human genes when a YAC contig is available across a candidate interval.  (+info)

*List of mammals of Poland

Cricetinae Genus: Cricetus European hamster Cricetus cricetus LR/lc Subfamily: Arvicolinae Genus: Ondatra Muskrat Ondatra ...

*Phodopus

Musser, G.G.; Carleton, M.D. (2005). "Subfamily Cricetinae". In Wilson, D.E.; Reeder, D.M. Mammal Species of the World: A ... Phodopus, a genus of rodents in the hamster subfamily Cricetinae-a division of the larger family Cricetidae-is a lineage of ... The genus Phodopus is one of three well-supported lineages in Cricetinae, the other two being the genus Mesocricetus and the ... Phodopus is sister to all other Cricetinae (meaning that it is the first lineage to diverge in the clade). Using several ...

*Cheek pouch

"ADW: Cricetinae: INFORMATION". Animal Diversity Web. Retrieved 2012-11-03. Klabunde RE, Calvello C (November 1995). "Inhibition ... subfamily Cricetinae) is food hoarding. Hamsters carry food to their underground storage chambers using their spacious cheek ...

*Pseudoryzomys

Two new genera of South American rodents (Cricetinae). Proceedings of the Biological Society of Washington 72:5-10. Hershkovitz ...

*Roborovski hamster

access-date= requires ,url= (help) Vorontsov, N.N (1960). "Species of Palaearctic hamsters (Cricetinae, Rodentia) in statu ... Cricetinae Murray, 1866) der Paläarctic". Zeitschrift für Säugetierkunde (in German). 20: 129-149. , ...

*Unavailable name

Supplementary notes on Neotropical Oryzomys dimidiatus and Oryzomys hammondi (Cricetinae). Journal of Mammalogy 51(4): 789-794 ...

*Oryzomys

A new rice rat of the Oryzomys palustris group (Cricetinae, Muridae) from northwestern Colombia, with remarks on distribution ( ... Supplementary notes on Neotropical Oryzomys dimidiatus and Oryzomys hammondi (Cricetinae) (subscription required). Journal of ...

*Oryzomys dimidiatus

A systematic review of the Neotropical water rats of the genus Nectomys (Cricetinae). Miscellaneous Publications, Museum of ... Supplementary notes on Neotropical Oryzomys dimidiatus and Oryzomys hammondi (Cricetinae) (subscription required). Journal of ...

*Mindomys

Supplementary notes on Neotropical Oryzomys dimidiatus and Oryzomys hammondi (Cricetinae) (subscription required). Journal of ...

*Nephelomys keaysi

A systematic review of the Neotropical water rats of the genus Nectomys (Cricetinae). Miscellaneous Publications Museum of ...

*Hamster

Subfamily Cricetinae Genus Allocricetulus Species A. curtatus-Mongolian hamster Species A. eversmanni-Eversmann's or Kazakh ... Hamsters are rodents (order Rodentia) belonging to the subfamily Cricetinae, which contains about 25 species classified in six ... Some similar rodents sometimes called "hamsters" are not currently classified in the hamster subfamily Cricetinae. These ... Taxonomists generally disagree about the most appropriate placement of the subfamily Cricetinae within the superfamily Muroidea ...

*Transandinomys bolivaris

Karyotypic variation in oryzomyine rodents (Cricetinae) with comments on chromosomal evolution in the Neotropical cricetine ...

*Golden hamster

The golden hamster, or Syrian hamster (Mesocricetus auratus) is a member of the subfamily Cricetinae, the hamsters. In the wild ...

*Posterolateral palatal pits

... and a reappraisal of the dichotomy within New World Cricetinae". Miscellaneous Publications. Museum of Zoology, University of ...

*Sphenopalatine vacuities

... and a reappraisal of the dichotomy within New World Cricetinae. Miscellaneous Publications, Museum of Zoology, University of ...

*Isthmomys

... and a reappraisal of the dichotomy within New World Cricetinae. Cuartas-Calle, Carlos Auturo and Javier Muñoz-Arango. 2003. ...

*Oryzomys gorgasi

A new rice rat of the Oryzomys palustris group (Cricetinae, Muridae) from northwestern Colombia, with remarks on distribution ( ...

*2014 in mammal paleontology

Raquel López-Antoñanzas; Pablo Peláez-Campomanes; Ángeles Álvarez-Sierra (2014). "New Species of Rotundomys (Cricetinae) from ...

*Bibimys

Hershkovitz, P. "South American swamp and fossorial rats of the scapteromyine group (Cricetinae, Muridae) with comments to the ...

*List of mammals of Jordan

Cricetinae Genus: Cricetulus Grey dwarf hamster Cricetulus migratorius LR/nt Subfamily: Arvicolinae Genus: Microtus Günther's ...

*List of mammals of Moldova

Cricetinae Genus: Cricetulus Grey dwarf hamster Cricetulus migratorius LR/nt Subfamily: Arvicolinae Genus: Clethrionomys Bank ...

*List of mammals of China

Cricetinae Genus: Allocricetulus Mongolian hamster Allocricetulus curtatus LR/lc Genus: Cansumys Gansu hamster Cansumys canus ...

*List of mammals of Belgium

Cricetinae Genus: Cricetus European hamster Cricetus cricetus LR/lc Subfamily: Arvicolinae Genus: Arvicola Water vole Arvicola ...

*List of mammals of the Palestinian territories

Cricetinae Subfamily: Arvicolinae Genus: Microtus Günther's vole, Microtus guentheri LC Family: Muridae (mice, rats, gerbils) ...

*Cricetidae

... muskrat Cricetinae - hamsters Democricetodontinae † (fossil) Neotominae - North American rats and mice, including deer mice, ...
About 10% of the Chinese population are chronic carriers of hepatitis B virus (HBV). Thus, the development of a highly efficient process for the preparation of a vaccine based on a recombinant hepatitis B surface antigen (HBsAg) is very important to the Chinese national immunization program. To this end, the ion exchange chromatography recovery of CHO-HBsAg from a recombinant Chinese hamster ovary cell line was shown to increase from about 55 to 80% by the addition of 1% poly(ethylene glycol) (PEG 10,000) to the mobile phase. Furthermore, based on analysis by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), the intact glycoprotein form of CHO-HBsAg was completely preserved by the addition of PEG. In the absence of PEG the glycoprotein form of CHO-HBsAg was also spread out into the high salt elution fraction. High-performance size-exclusion chromatography with on-line multiangle-laser-light scattering (HPSEC-MALLS) analysis was performed to monitor the status of the ...
We have isolated three independent Chinese hamster ovary cell mutants (B3853, I223, and M311) with temperature-sensitive, pleiotropic defects in receptor-mediated endocytosis. Activities affected at 41 degrees C include uptake via the D-mannose 6-phosphate receptor, accumulation of Fe from diferric transferrin, uptake of alpha 2-macroglobulin, compartmentalization of newly synthesized acid hydrolases, resistance to ricin, and sensitivity to diphtheria and Pseudomonas toxins and modeccin. The three mutants also displayed decreased sialylation of some secreted glycoproteins at 41 degrees C, reminiscent of the nonconditional mutant DTG1-5-4 that showed both endocytic and Golgi-associated defects (Robbins, A.R., C. Oliver, J.L. Bateman, S.S. Krag, C.J. Galloway, and I. Mellman, 1984, J. Cell Biol., 99:1296-1308). Phenotypic changes were detectable within 30 min after transfer of the mutants to 41 degrees C; maximal alteration of most susceptible functions was obtained 4 h after temperature shift. At ...
L-Histidine markedly increased the growth- and DNA synthesis-inhibitory effects elicited by hydrogen peroxide in cultured Chinese hamster ovary cells. DNA single-strand breakage was also higher in the presence of the amino acid and, in addition, these breaks were characterized by a slower rate of repair, compared with that of the breaks generated by the oxidant alone. In the presence of L-histidine, hydrogen peroxide also produced DNA double-strand breakage, a lesion that cannot be detected in cells treated with even exceedingly high concentrations of the oxidant alone. Data reported herein suggest that the L-histidine-mediated increase of the cytotoxic response of cultured Chinese hamster ovary cells to hydrogen peroxide may be at least partially dependent on the formation of DNA double-strand breaks. ...
COUPLING OF MUSCARINIC M1, M2 AND M3 ACETYLCHOLINE-RECEPTORS, EXPRESSED IN CHINESE-HAMSTER OVARY CELLS, TO PERTUSSIS-TOXIN-SENSITIVE INSENSITIVE GUANINE-NUCLEOTIDE-BINDING ...
Protein ectodomain shedding, the proteolytic release of the extracellullar domain of membrane-tethered proteins, can dramatically affect the function of cell surface receptors, growth factors, cytokines, and other proteins. In this study, we evaluated the activities involved in ectodomain shedding of p75NTR, a neurotrophin receptor with critical roles in neuronal differentiation and survival. p75NTR is shed in a variety of cell types, including dorsal root ganglia cells and PC12 cells. In Chinese hamster ovary cells, inhibitors of the MEK/ERK and p38 MAP kinase pathways uncovered distinct signaling pathways required for the constitutive and stimulated shedding of p75NTR. Stimulated p75NTR shedding is abrogated in M2 mutant Chinese hamster ovary cells that lack functional tumor necrosis factor-alpha converting enzyme (TACE, also referred to as ADAM17) and in cells isolated from adam17-/- mice, but not in cells from adam9/12/15-/- or adam10-/- mice. Stimulated p75(NTR) shedding is strongly reduced ...
Cabral, F; Gottesman, M M.; Zimmerman, S B.; and Steinert, P M., "Intermediate filaments from chinese hamster ovary cells contain a single protein. Comparison with more complex systems from baby hamster kidney and mouse epidermal cells." (1981). Subject Strain Bibliography 1981. 19 ...
BioAssay record AID 51937 submitted by ChEMBL: K+ channel blocking activity in Chinese hamster ovary cells expressing HERG Kv11.1.
Mitotic Spindle Proteomics in Chinese Hamster Ovary Cells. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
The Antibody Labs proprietary cell line development technology enables drug developers to move seamlessly from preclinical discovery to manufacture of the biologic for clinical testing. BESTcell clonal Chinese hamster ovary cell lines can be rapidly generated to enable preclinical testing of multiple biologic drug candidates. After selection of the final candidate, the respective cell line can be used to manufacture master cell banks. This revolutionary approach shortens timelines and reduces the reproducibility risk associated with changing the source of the biologic during research and development.
Anti-Chinese Hamster Ovary Cell Host Cell Proteins (CHO-HCPs) IgG, aff pure Antibodies 800-140-11A-100 Anti-Chinese Hamster Ovary Cell Host Cell Proteins (CHO-HCPs) IgG, aff pure Antibodies 800-140-11A-100
The elevation of expression levels for secreted glycoproteins by gene amplification in mammalian cells shows a saturation behavior at high levels of gene amplification. At high expression levels a drop in the secretion efficiency for the recombinant
The CHOZN Platform is a CHO (Chinese Hamster Ovary) mammalian cell expression system for the fast and easy selection and scale up of clones producing high levels of recombinant proteins.
Is there anybody who get a stabile transformation with the pcDNA3 vector (INVITROGEN) in BHK21 (baby hamster kidney) cells and what was the level of overexpression compared to a normal cell line expressing the inserted cDNA? Thanks Dietmar ...
The purpose of this study is to assess the safety, pharmacokinetic and activity profiles of the ch14.18 antibody produced in cells of hamster origin (ch
BioAssay record AID 41661 submitted by ChEMBL: Beta-3 agonist efficacy in an adenylate cyclase assay performed on chinese hamster ovary cells transfected with human Beta-3 adrenergic receptor; Inactive.
TY - JOUR. T1 - Dietary D-allulose alters cholesterol metabolism in Golden Syrian hamsters partly by reducing serum PCSK9 levels. AU - Kanasaki, Akane. AU - Jiang, Zhe. AU - Mizokami, Takuya. AU - Shirouchi, Bungo. AU - Iida, Tetsuo. AU - Nagata, Yasuo. AU - Sato, Masao. PY - 2019/9/1. Y1 - 2019/9/1. N2 - D-Allulose, a C-3 epimer of D-fructose, is a rare sugar reported to be a non-caloric sweetener having several health beneficial effects including anti-hyperglycemia and anti-obesity. However, the impact of dietary D-allulose on cholesterol metabolism remains unclear. Therefore, we studied the effects of D-allulose on the cholesterol metabolism of Golden Syrian hamsters, an animal model with a lipid metabolism similar to that of humans. Hamsters received either normal diet (ND) or high-fat diet (HFD) with or without 3% D-allulose for 4 or 8 weeks. While there were no significant differences in total serum cholesterol levels between the groups, D-allulose significantly increased HDL-cholesterol ...
Phodopus campbelli is very small in size and the pelage is short and silky. The underside of the animal is covered in soft, buff, light grey fur and the dorsal portions, including the head, are woody brown in color. The underfur is quite short and is a dark slate grey. A defined charcoal stripe runs from between the ears to the tail. The pads of all digits, and the small tail, are covered in silky white fur. Additionally, Campbells hamsters, like other members of the subfamily Cricetinae, possess large internal cheek pouches that terminate above the scapula. Males are larger than females. (Thomas, 1905). Phodopus campbelli is often confused with Phodopus sungorus, Siberian hamsters. However, there are several physical characteristics that distinguish the two species. The ears of Phodopus campbelli are generally smaller than those of Phodopus sungorus. The mid-dorsal stripe of the Campbells hamster is both thin and defined and the area where the dorsal fur meets the ventral fur is a creamy ...
Human apolipoprotein (apo) A-I is secreted as a proprotein of 249 amino acids and is processed extracellularly to the mature form (243 amino acids) by removal of a six-residue propeptide segment. We have examined the role of the apoA-I propeptide in intracellular transport and secretion using transfected baby hamster kidney cells that secreted either proapoA-I (from the wild-type cDNA, A-Iwt) or mature-form apoA-I (from A-I delta pro, a cDNA in which the propeptide sequence was deleted). Deletion of the propeptide from the apoA-I sequence did not affect the rate of apoA-I synthesis, nor did it affect the fidelity of proteolytic removal of the prepeptide. However, the propeptide deletion caused mature-form apoA-I to accumulate within the cells as determined by pulse-chase experiments; the intracellular retention times for the mature-form apoA-I in which the propeptide was prematurely removed was three times longer than that of proapoA-I (t1/2 , 3 h compared with approximately 50 min). There was ...
Goat anti-Golden Syrian hamster IgG recognizes Golden Syrian hamster IgG whole molecule. This secondary antibody was purified using antigen affinity chromatography. The antibody is conjugated with Rhodamine. Golden Syrian hamster IgG whole molecule (PAB10592) - Products - Abnova
Rabbit anti-Golden Syrian hamster IgG recognizes Golden Syrian hamster IgG whole molecule. This secondary antibody was purified using antigen affinity chromatography. Golden Syrian hamster IgG whole molecule (PAB9233) - Products - Abnova
The effect of hyperosmolarity on transient recombinant protein production in Chinese hamster ovary (CHO) cells was investigated. Addition of 90 mM NaCl to the production medium ProCHO5 increased the volumetric yield of recombinant antibody up to 4-fold relative to transfection in ProCHO5 alone. Volumetric yields up to 50 mg l(-1) were achieved in a 6 day batch culture of 3 l. In addition, hyperosmolarity reduced cell growth and increased cell size. The addition of salt to cultures of transiently transfected CHO cells is a simple and cost-effective method to increase TGE yields in this host. Zhang, Xiaowei; Garcia, Isabel Fernandez; Baldi, Lucia; Hacker, David L.; Wurm, Florian M.
Effects of granulocyte-macrophage colony stimulating factor produced in Chinese hamster ovary cells (regramostim), Escherichia coli (molgramostim) and yeast (sargramostim) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy.
CABRERA, Felipe. Assessing working and reference memory in golden hamsters (Mesocricetus Auratus): A Spatial-memory Task. Rev. mex. anál. conducta [online]. 2009, vol.35, n.spe, pp.117-132. ISSN 0185-4534.. Reference and working memory in foragers are supposedly a foremost processes mechanism to gain energy while searching for food. These processes allows the animal to identify invariable arrangements in the environment indicating rich and lean places containing food, and those places that the organism itself has depleted. In this experiment, four hamsters hoarded for food in an enclosure that continually provided food in some places, but never offered food in one particular location of the enclosure. Hamsters should identify the non-baited place in order leave it out and avoid the previously visited patches where the food was depleted. Results showed that subjects omitted select the non-baited location, increasing systematically this trend throughout the sessions.. Palabras llave : reference ...
Adhering CHO cell culture - posted in Tissue and Cell Culture: Hi, I am totally new to CHO (chinese hamster ovary) cell culture, and to make things worse, I am in charge now of five different mutant CHO cell lines received by donation (4 day-travel and customs) . So the thing is that to not make mistakes I am growing them in a rich Hams F12 medium containing 10% FBS, pen-streptomycin, glutamine, and non essential amino-acids. They grow quite well according to their passage number,...
Cell surface ADA needs to be anchored to the plasma membrane by means of specific receptors. In lymphocytes, CD26 has been described as an ADA-anchoring protein. In nonlymphoid cells it has been reported that A1 adenosine receptors can anchor ADA to the cell surface. Both ADA/CD26 and ADA/A1R interactions are functionally important, as ADA/CD26 have a costimulatory role in the lymphocytes and ADA facilitates ligand binding to A1R and regulates signal transduction (Franco et al., 1997a,b). In this article, we report a third protein able to interact with ADA on the cell surface, the A2BR. The use of CHO cells transfected with the human cDNA for the A2BR was important to demonstrate the differences between the interactions of ADA/CD26 and ADA/A2BR. Wild-type CHO cells express hamster CD26, and it is well-reported (Dong et al., 1997) that rodent CD26 is unable to bind ADA (either human or rodent ADA). Therefore, cell surface ADA cannot be detected in CHO cells despite the fact that these cells have ...
The parent line of BHK-21(C-13) was derived from baby hamster kidneys of five unsexed, 1-day-old hamsters in March, 1961, by I.A. Macpherson and M.G.P. Stoker. Following 84 days of continuous cultivation, interrupted only by an 8-day preservation by freezing, clone 13 was initiated by single-cell isolation.
The parent line of BHK-21(C-13) was derived from baby hamster kidneys of five unsexed, 1-day-old hamsters in March, 1961, by I.A. Macpherson and M.G.P. Stoker. Following 84 days of continuous cultivation, interrupted only by an 8-day preservation by freezing, clone 13 was initiated by single-cell isolation.
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. Directly dephosphorylates CDK1 and activates its kinase activity. When phosphorylated, highly effective in activating G2 cells into prophase (By similarity).
Used for carcinoma cells, rat skeletal myoblasts, Chinese hamster lung cells, and rat, rabbit, and chicken embryos. Corning™ cellgro™ DMEM/Hams Medium F-12 Mix is based on Hams F-10 medium with increased concentrations of choline, inositol, putrescine, and several amino acids. X6 500 mL Hams F-12 Medium w L-glut ...
Expression of cytokines in tumor cells provides a sensitive modality to analyze the consequences of local cytokines in vivo on tumor infiltrating cells and tumorigenicity. We have transfected Chinese hamster ovary (CHO) cells with an interleukin 10 (IL-10) expression vector. CHO-IL10 cells although unaltered with respect to their in vitro growth lost tumorigenicity, both in nude and in SCID mice and in an IL-10 dose dependent manner. In addition, CHO-IL10 cells suppressed the growth of equal numbers of coinjected but not of contralaterally injected CHO cells. Immunohistology with anti-CR3/Mac-1 and anti-Mac-3 monoclonal antibodies revealed that CHO tumors were substantially infiltrated by macrophages. However, in CHO-IL10 tumors macrophages were virtually absent within the tumor tissue. Our results suggest that IL-10 indirectly suppresses tumor growth of certain tumors by inhibiting infiltration of macrophages which may provide tumor growth promoting activity.. ...
p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.,/p> ,p>,a href="/manual/evidences">More…,/a>,/p> ...
When exponentially growing CHO cells were deprived of arginine (Arg), cell multiplication ceased after 12 h, but initiation of DNA synthesis continued: after 48 h of starvation with continuous [3H]thymidine exposure, 85% of the population had incorpo
A monoclonal antibody (IgG1) has been prepared that specifically detects Chinese hamster ovary cells expressing a multidrugresistant phenotype. This antibody recognizes the membrane P-glycoprotein (Mr 170,000) associated with drug resistance as determined by enzyme-linked immunosorbent assay with purified P-glycoprotein and by Western blot analysis of cell extracts from drug-resistant and drug-sensitive cells. By immunofluorescence methods, the antibody also reacts strongly with viable and ether:ethanol-fixed resistant cells but does not react with the parent drug-sensitive cell line. Thus, this antibody can bind with live cells allowing discrimination by immunohistochemistry between drug-resistant and drug-sensitive Chinese hamster ovary cells.. ...
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Proteolytic processing of PA triggers partitioning of the anthrax toxin into lipid rafts. (A) Wild-type CHO cells were incubated for 1 h at 4°C with 500 ng/ml
MGAT1 adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) structure. Goh et al. reported increased sialylation after restoring MGAT1 function in MGAT1 deficient CHO cells.
I am trying to determine the best dose of hygromycin that i can use to select my transfected colonies. (working with chinese hamster cell lines). I have tried several concentrations (from 50-250 microgram per ml) on my host cells and changing the media plus antibiotic every 1-2 days. Each time the media has turned yellow and lots of dead cells but still surviving colonies can be seen. How could we know if the cell death is because of the overgrowth of the culture and consequent bad condition or because of the antibiotic?. ...
First off, a VERY IMPORTANT NOTE. Mulder is a Roborovski hamster, which is the smallest of the dwarf hamsters. When Scully died, he weighed 22g, or 0.78oz; robos are usually less than 30g, or 1.06oz. Other dwarf hamsters are slightly larger, and can weigh up to 2.5oz. Syrian hamsters, on the other hand, usually weigh 5-7oz. This house is a little less than 450 square inches, which is a decent size for a dwarf hamster, but would be entirely too small for a Syrian hamster. If you need a house for a Syrian hamster, I highly recommend that you consider adapting these instructions for a much larger table, such as the Lack coffee table or two or more connected Lack side tables ...
View mouse Xrcc3 Chr12:111803192-111813873 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
Reaktivität: Huhn, Rind (Kuh), Hund and more. 370 verschiedene XRCC6 Antikörper vergleichen. Alle direkt auf antikörper-online bestellbar!
A research team at the Northeast Agricultural University in Harbin managed to breed three transgenic pigs by injecting fluorescent green protein and a "bunch of other junk" into embryonic pigs, said Professor Liu Zhonghua. Liu wore a fancy white lab coat and had multiple degrees adorning his walls, so we assume he must be pretty smart ...
... Fast Track Project commissioned, loop tuned, validated for initial startup Wrote and executed all FAT, validation protocols on site.
The resulting list of "discovered" genes and proteins, when compared to the genetic information already known about humans and cold virus, proved extremely successful and demonstrated the power of this method.. A similar analysis of hamster cells provided directly observed evidence for the existence of thousands of genes and proteins in hamsters in a single relatively inexpensive experiment. Direct evidence for the existence of almost all of theses genes and proteins in hamsters is not available in the official lists of hamster genes and proteins.. Dr Matthews added: "These findings open up the potential to take powerful analysis tools currently used to study human diseases and apply them to study any animal, insect or even plants - something previously either very challenging or simply not possible. This technique will also make it easier and much more efficient for scientists to study anything from farm animals and their diseases to insect pests that damage crops.. "In recent years, a number ...
Sundaram, H., Strange, Philip G. (1994) Characterisation of the human brain serotonin 5-HT1A receptor expressed in Chinese Hamster Ovary cells. Biochemical Society Transactions, 22 (1). S75-S75. ISSN 0300-5127. (doi:10.1042/bst022075s) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) ...
The best Leupold Golden Ring binoculars are top rated birding binoculars without sky-high prices. Read our Leupold Golden Ring reviews & find the best for you
September 05, 2017 - November 01, 2017. The CHOC Childrens Foundation is a proud to announce that we will be a sponsor for the acclaimed Orange County-based series on managing money and estate planning.. ...
A Googler declares: Its Golden age for hardware guys. I say, Really? We all sense radical changes afoot. I asked young engineers/researchers what they see as bottlenecks to innovation.
The Remarkable Golden Ratio Part 1 is an introduction to what the Golden Ratio is numerically and why it is important to be observed in design.
产品:invitrogen货号:K1483规格:2×10^6cells名称:GeneBLAzer®MC2R-CRE-bla-CHO-K1CellsTheGeneBLAzer®MC2R-CRE-bla-CHO-K1cellscontainthehumanmelanocortin-2receptor(MC2R),(Accession#NM_000529.1)andtheMe
We have that in common WitchGirl : ) I had a golden named skippy, thats how I came up with the nick. I donnt know if this is your first golden, but they are the smartest, most gentle and loving dogs around, ofcorse Im patial to them, always will be ...
Incubation of adriamycin resistant Chinese hamster lung cells with low levels of N-ethylmaleimide (NEM) results in a major increase in the cellular accumulation of drug. When resistant cells are prelabeled with [32Pi] and thereafter treated with NEM there also occurs a selective superphosphorylation of an 180K plasma membrane glycoprotein (P-180). This phosphorylation reaction occurs at both serine and threonine residues. In similar experiments with drug sensitive cells only minor levels of this protein can be detected. Detailed studies have established that in cells which have reverted to drug sensitivity there is a parallel loss in the presence of phosphorylated P-180. Also in cells which have undergone partial reversion to drug sensitivity there is a correlation between levels of superphosphorylated P-180 and adriamycin resistance. These results provide evidence that adriamycin resistance is dependent on the presence of P-180. The results also suggest that the biological activity of this protein is
The effect of thymol (TOH), a dietary compound was investigated for its ability to protect against radiation induced cytotoxicity in Chinese hamster lung fibroblast (V79) cells growing in vitro. Treatment of V79 cells with 25�g/ml of TOH prior to 10 Gy gamma radiation resulted increase in the cell viability than that of radiation alone as evaluated by MTT assay. Similarly, there was a significant increase in the surviving fraction observed with 25�g/ml of TOH administered 1 h prior to graded doses of gamma radiation. Further, 25�g/ml TOH treatment before irradiation significantly decreased the percentage of radiation induced apoptotic cells (sub-G1 population) analyzed by flow cytometry as well as DNA ladder assay. TOH was found to inhibit various free radicals generated in vitro, viz., DPPH, O2•, ABTS•+ and OH• in a concentration dependent manner. TOH also inhibited the radiation-induced decrease in intracellular glutathione, superoxide dismutase and catalase enzyme levels in V79 ...
In the last years, particular interest has been given to investigations concerning natural, effective and nontoxic compounds with radioprotective capacity in concert with increasing utilization of different types of ionizing radiation for various applications. Among them, propolis, a resinous mixture of substances collected by honey bees (Apis mellifera) has been considered promising since it presents several advantageous characteristics, i.e., anti-inflamatory, anticarcinogenic, antimicrobial and free-radical scavenging action. It is, therefore, a direct antioxidant that protects cells and organisms from the adverse effects of ionizing radiation. These relevant biological activities are mainly mediated by the flavonoids, present at relatively high concentrations in the propolis. Considering that the chemical composition and, consequently, the biological activity of propolis is variable according to the environmental plant ecology, the present study was conducted in order to evaluate the ...
Maurocalcine (MCa), initially identified from a Tunisian scorpion venom, defines a new member of the family of cell penetrating peptides by its ability to efficiently cross the plasma membrane. The initiating mechanistic step required for the cell translocation of a cell penetrating peptide implicates its binding onto cell surface components such as membrane lipids and/or heparan sulfate proteoglycans. Here we characterized the interaction of wild-type MCa and MCa K20A, a mutant analogue with reduced cell-penetration efficiency, with heparin (HP) and heparan sulfates (HS) through surface plasma resonance. HP and HS bind both to MCa, indicating that heparan sulfate proteoglycans may represent an important entry route of the peptide. This is confirmed by the fact that (i) both compounds bind with reduced affinity to MCa K20A and (ii) the cell penetration of wild-type or mutant MCa coupled to fluorescent streptavidin is reduced by about 50% in mutant Chinese hamster ovary cell lines lacking either all
Somatic Cell and Molecular Genetic Analysis of Various Chinese Hamster Ovary (CHO) Mutant Cells Defective in Sterol-dependent Regulation of Cholesterol Biosynthesis and LDL Receptor Expression A Thesis Submitted to the Faculty in partial fulfillment of the requirements for the degree of Doctor of Philosophy by Mazahir Tahir Hasan Dartmouth College and Dartmouth Medical school Hanover, New Hampshire April 1993 ...
Somatic Cell and Molecular Genetic Analysis of Various Chinese Hamster Ovary (CHO) Mutant Cells Defective in Sterol-dependent Regulation of Cholesterol Biosynthesis and LDL Receptor Expression A Thesis Submitted to the Faculty in partial fulfillment of the requirements for the degree of Doctor of Philosophy by Mazahir Tahir Hasan Dartmouth College and Dartmouth Medical school Hanover, New Hampshire April 1993 ...
We attempted to alter the inherited myocardial damage and loss of contractility of the cardiomyopathic Syrian hamster (strain U-MX7-1) by giving cardiac drugs that altered intracellular calcium and myocardial workload. Thirty-seven 21-day-old cardiomyopathic and thirty-seven 21-day-old normal hamsters were divided into five groups each: verapamil-, propranolol-, digoxin-, hydralazine-, and saline-injected. On their 90th day of life, the hamsters were killed. Of the five cardiomyopathic groups, only verapamil reduced myocardial damage. When both "control" and cardiomyopathic hamsters were treated with saline, digoxin, or propranolol, the cardiomyopathic hamsters had significantly less contractile force, maximal rate of force development, and maximum velocity of unloaded shortening. When both groups were treated with verapamil or hydralazine, there were no significant group differences in the indices of contractility. However, when saline-treated cardiomyopathic hamsters were compared with ...
Chinese hamster ovary (CHO) cells are an epithelial cell line derived from the ovary of the Chinese hamster, often used in biological and medical research and commercially in the production of therapeutic proteins. They have found wide use in studies of genetics, toxicity screening, nutrition and gene expression, particularly to express recombinant proteins. CHO cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics. The Chinese hamster had been used in research since 1919 where they were used in place of mice for typing pneumococci. They were subsequently found to be excellent vectors for transmission of kala-azar (a.k.a. visceral leishmaniasis), facilitating leishmania research. In 1948, the Chinese hamster was first used in the United States for breeding in research laboratories. In 1957, Theodore T. Puck obtained a female Chinese hamster from Dr. George Yerganians laboratory at the Boston Cancer Research Foundation and used it to ...
BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies covering a wide range of subjects in life sciences and medicine. The journal is divided into 55 subject areas.
Kukkonen JP; G-protein-dependency of orexin/hypocretin receptor signalling in recombinant Chinese hamster ovary cells.; Biochem Biophys Res Commun, 2016 PubMed Europe PMC ...
Mesocricetus é um gênero de roedores da família Cricetidae. Mesocricetus auratus (Waterhouse, 1839) Mesocricetus brandti (Nehring, 1898) Mesocricetus newtoni (Nehring, 1898) Mesocricetus raddei (Nehring, 1894) MUSSER, G. G.; CARLETON, M. D. Superfamily Muroidea. In: WILSON, D. E.; REEDER, D. M. (Eds.). Mammal Species of the World: A Taxonomic and Geographic Reference. 3. ed. Baltimore: Johns Hopkins University Press, 2005. v. 2, p. 894-1531 ...
To rapidly produce large amounts of recombinant proteins, the generation of stable Chinese Hamster Ovary (CHO) cell pools represents a useful alternative to large-scale transient gene expression (TGE). We have developed a cell line (CHO(BRI/rcTA)) allowing the inducible expression of recombinant proteins, based on the cumate gene switch. After the identification of optimal plasmid DNA topology (supercoiled vs linearized plasmid) for PEIpro™ mediated transfection and of optimal conditions for methionine sulfoximine (MSX) selection, we were able to generate CHO(BRI/rcTA) pools producing high levels of recombinant proteins. Volumetric productivities of up to 900mg/L were reproducibly achieved for a Fc fusion protein and up to 350mg/L for an antibody after 14days post-induction in non-optimized fed-batch cultures. In addition, we show that CHO pool volumetric productivities are not affected by a freeze-thaw cycle or following maintenance in culture for over one month in the presence of MSX. ...
Following treatment of Syrian hamster embryo cells with benzo(a)pyrene, the time required for the expression of enhanced fibrinolytic activity was examined. For this study, the fibrin-agarose overlay method was developed to distinguish the activity of normal and transformed colonies of hamster cells. Colonies possessing enhanced fibrinolytic activity were not observed 8 days after treatment, but they were observed following one passage (2 weeks after treatment). Morphologically transformed colonies, which exhibited no enhanced fibrinolytic activity, were observed 8 days following treatment. In contrast to these two early changes, cells capable of growth in soft agar were observed much later (6 to 8 weeks after treatment). Untreated Syrian hamster embryo cells generally senesced and did not exhibit enhanced fibrinolytic activity. Approximately 1 of 10 untreated cultures escaped senescence and evolved as a continuous cell line; such cultures frequently exhibited enhanced fibrinolytic activity. ...
The development of receptor-defective or -deficient mutants can be applied to the investigation of cell-matrix interactions including cell adherence and spreading. In the present study we developed a series of ethyl methyl sulfonate (EMS)-induced Chinese hamster ovary (CHO) cell mutants, which adhere to fibronectin but have impaired spreading characteristics. Using morphometric analysis, a significant suppression in the degree of cell spreading between the wild-type and the mutant cells (P less than 0.001) was seen. This inability of the mutant cells to spread adequately on fibronectin also resulted in a decreased number and diameter of stress fibers as compared to wild-type cells. The decreased cell spreading of the mutant cells was not due to inherent differences in cell size or volume, as determined by fluorescence-activated cell sorter (FACS) analysis. Since integrins, specifically the fibronectin receptor (alpha FN/beta 1), are important in cell adhesion and cell spreading, we carried out a ...
DESCRIPTION (provided by applicant): The long term goal of this research is to develop an efficient method to authenticate rodent cell lines. Misidentification as well as inter- and intra-species cross contamination of cell lines is widespread and has a substantial negative impact on biomedical research. The use of short tandem repeat (STR) analysis has been shown to be an effective means of authenticating human cell lines, STR genetic profiles have been established for a large number of human cell lines, and much of this data is publicly accessible in the ATCC STR Profile Database. Equivalent resources do not currently exist for authentication of rodent cell lines. In order to fill this gap, the specific aims of this application are to develop a multiplex microsatellite marker-based test to generate unique genetic profiles for mouse and rat cell lines and to build a database of these profiles to use for rodent cell line authentication. By developing these resources, it will be possible to ...
Recently released sequence information on Chinese hamster ovary (CHO) cells promises to not only facilitate our understanding of these industrially important cell factories through direct analysis of the sequence, but also to enhance existing methodologies and allow new tools to be developed. In this article we demonstrate the utilization of CHO specific sequence information to improve mass spectrometry (MS) based proteomic identification. The use of various CHO specific databases enabled the identification of 282 additional proteins, thus increasing the total number of identified proteins by 4050%, depending on the sample source and methods used. In addition, a considerable portion of those proteins that were identified previously based on inter-species sequence homology were now identified by a larger number of peptides matched, thus increasing the confidence of identification. The new sequence information offers improved interpretation of proteomic analyses and will, in the years to come, ...
Normal Hamster (Syrian) control serum (non-immunized) Mixed breed serum GC-NGHS-5 Normal Hamster (Syrian) control serum (non-immunized) Mixed breed serum GC-NGHS-5
BGI, the giant genomics institute located in Shenzhen, and GT Life Sciences of San Diego have published their collaborative study on the genomic sequence of the Chinese hamster ovary (CHO) K1 cell line in Nature Biotechnology. Over 70% of the recombinant therapeutic proteins sold today are manufactured using mammalian cells, primarily CHO cell lines. GT Life Sciences uses a metabolic modeling platform to design new products and processes for the life sciences field. It says a better understanding of the genome will speed development of new recombinant protein therapies. More details.... Share this with colleagues:   var switchTo5x=true;stLight.options({publisher:d7871f5b-67bc-4d30-b66f-1465d0b97213});
This study shows that the increase in blood pressure triggered by Ang II infusion can be completely prevented by the administration of soluble human rACE2. We used a highly purified soluble human rACE2 produced in the Chinese hamster ovary cell line, which has a calculated half-life in vivo of 8.5 hours (please see the supplementary Methods section). Our protocols involved acute studies in anesthetized animals and studies where rACE2 was given by osmotic minipumps for 3 days to conscious animals. Studies of long duration with human rACE2 administration were precluded because we found that mouse antihuman rACE2 antibodies developed over time, and this resulted in a decrease in serum ACE2 activity despite continued rACE2 infusion (please see the supplementary Results section).. As expected from the known effect of ACE2 on Ang II,2,3 human rACE2 was shown in vitro to cleave a single amino acid phenylalanine from Ang II, which led to the formation of Ang-(1-7). Recombinant ACE2 also acted on Ang I ...
Sou SN, Lee K, Nayyar K, Polizzi KM, Sellick C, Kontoravdi Cet al., 2017, Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc-glycosylation., Biotechnol Bioeng Transient gene expression (TGE) is a methodology employed in bioprocessing for the fast provision of recombinant protein material. Mild hypothermia is often introduced to overcome the low yield typically achieved with TGE and improve specific protein productivity. It is therefore of interest to examine the impact of mild hypothermic temperatures on both the yield and quality of transiently expressed proteins and the relationship to changes in cellular processes and metabolism. In this study, we focus on the ability of a Chinese hamster ovary cell line to galactosylate a recombinant monoclonal antibody (mAb) product. Through experimentation and flux balance analysis, our results show that TGE in mild hypothermic conditions led to a 76% increase in qP compared to TGE at 36.5°C in our ...
Clarified Cell Culture Fluid (CCCF)/Bulk Harvest: To produce a fully human immunoglobulin G (IgG) antibody, we cultured Chinese hamster ovary (CHO) cells in bioreactors using chemically defined media and feeds. We removed cells from their culture suspension with body-feed filtration, then filtered the supernatant with a 0.2-µm grade filter before storing it at 2-8 °C until needed.. Chromatography Media and Systems: All membrane adsorbers came from Sartorius Stedim Biotech. For both laboratory- and pilot-scale experiments, we used Sartobind protein A 2-mL and 70-mL, Sartobind S 3-mL and 150-mL, and Sartobind Q 3-mL and 75-mL devices. ÄKTA Pure and ÄKTA PCC chromatographic systems from GE Healthcare hosted the lab-scale experiments. For pilot-scale evaluation, we used ÄKTA Process systems, also from GE Healthcare.. Lab-Scale Single-Use MAb Purification Process: Our single-use laboratory-scale purification process used Sartobind protein A 2-mL, Sartobind S 3-mL, and Sartobind Q 3-mL adsorbers. ...
Previous work on the early development of the golden hamster includes the investigation of Ochs (1908), Graves (1945) and Ward (1948), all at the level of the light microscope. Austin (1963) has examined the ultrastructure of the oocytes of the golden hamster while Enders & Schlafke (1965) have observed the pre-implantation stages of pregnancy.. The ultrastructure of implantation has been studied in two other species of myomorph rodents: the mouse (Potts, 1966a; Reinius, 1967) and the rat (Enders & Schlafke, 1967).. Implantation is taken as beginning when the zona pellucida is lost and the trophoblast is in contact with the uterine epithelium throughout its circumference. This takes place at between 80-100 h post coitum. Previous studies have been made on specimens embedded in paraffin, and the shrinkage which occurs with this method of preservation has caused implantation to appear to begin considerably later than this:Graves (1945) gives it as beginning at 5 days, Ward(1948) as 4 days 8 ...
Our stuffed guinea pigs and stuffed hamsters are squeak-tacular! Lets face it, a plush guinea pig and a plush hamster have one huge advantage over a real guinea pig or hamster; no cage. No cage means no cleaning and no odor when the cleaning gets put off
Feichtinger J., Hernandez I., Fischer C., Hanscho M., Auer N., Hackl M., Jadhav V., Baumann M., Krempl P.M., Schmidl C., Farlik M., Schuster M., Merkel A., Sommer A., Heath S., Rico D., Bock C., Thallinger G.G., Borth N. (2016) Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time. Biotechn. Bioeng. 113:10:2241-2253. DOI: 10.1002/bit.25990. Gludovacz E., Maresch D., Bonta M., Szöllösi H., Furtmüller P.G., Weik R., Altmann F., Limbeck A., Borth N., Jilma B., Boehm T. (2016) Characterization of recombinant human diamine oxidase (rhDAO) produced in Chinese Hamster Ovary cells. J Biotechnol. 227, 120-130. Klanert G., Jadhav V., Shanmukam V., Diendorfer A.m Karbiener M., Scheideler M., Bort JH., Grillari J., Hackl M., Borth N. (2016) A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines. J Biotechnol. DOI 10.1016/j.jiotec.2016.03.022. Priola J.J., Calzadilla N., Baumann M., Borth N., Tate ...
There are now several examples of single G protein-coupled receptors to which binding of specific agonists causes differential effects on the associated signaling pathways. The dopamine D2 receptor is of special importance because the selective activation of functional pathways has been shown both in vitro and in situ.
Matthew D Johnson is the author of this article in the Journal of Visualized Experiments: Measuring In Vivo Changes in Extracellular Neurotransmitters During Naturally Rewarding Behaviors in Female Syrian Hamsters
Photoporation is a rapidly expanding technique for the introduction of macromolecules into single cells. However, there remains no study into the true efficiency of this procedure. Here, we present a detailed analysis of transfection efficiency and cell viability for femtosecond optical transfection using a titanium sapphire laser at 800 nm. Photoporation of 4000 Chinese Hamster ovary cells was performed, representing the largest optical transfection study reported to date. We have investigated a range of laser fluences at the cell membrane and, at 1.2 μJ/cm2, have found an average transfection efficiency of 50 ± 10%. Contrary to recent literature, in which 100% efficiency is claimed, our measure of efficiency accounts for all irradiated cells, including those lost as a result of laser treatment, thereby providing a true biological measure of the technique.. ©2006 Optical Society of America. Full Article , PDF Article ...
Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1- ...
Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1- ...
File Title: The patterns of development and distribution of collagen, reticulin, and elastin in the placentae of the golden hamster (Mesocricetus auratus Waterhouse ...
iHOP - Information Hyperlinked over Proteins. iHOP provides the network of genes and proteins as a natural way of accessing the millions of abstracts in PubMed. By employing genes and proteins as hyperlinks between sentences and abstracts, the information in PubMed becomes bound together into one navigable resource. A Gene Network for Navigating the Literature, Nature Genetics 36, 664 (2004). www.ihop-net.org/UniPub/iHOP/
|ul| |li| CELLine AD 1000 Bioreactor Flask for high density adherent cell culture. |/li| |li| 1000ml media compartment 15 ml cell growth compartment for antibody and protein production. |/li| |li| Use with Hybridoma, Insect, CHO, NSO, HEK, BHK cell lines
|ul| |li| CELLine AD 1000 Bioreactor Flask for high density adherent cell culture. |/li| |li| 1000ml media compartment 15 ml cell growth compartment for antibody and protein production. |/li| |li| Use with Hybridoma, Insect, CHO, NSO, HEK, BHK cell lines
There is no consensus as to whether NA activates the influx of extracellular Ca2+ influx in CHO-α1A, CHO-α1B, and CHO-α1D (Perez et al., 1993; Horie et al., 1995). Based on the results of the present study, we conclude that NA induces Ca2+ influx in CHO-α1A, CHO-α1B, and CHO-α1D (Figs. 1 and 4). Moreover, the magnitude of the transient increase and that of the sustained increase in [Ca2+]i were similar in all three cell types (Figs. 1 and 2). These results differ from the previous observation that the level of the NA-induced sustained increase in [Ca2+]i in CHO-α1D was smaller than that in CHO-α1A or CHO-α1B(Horie et al., 1995). However, this report showed that NA induced sustained increase in [Ca2+]i even in the absence of extracellular Ca2+ in CHO-α1A or CHO-α1B(Horie et al., 1995). Therefore, we have doubts about their data on monitoring of NA-induced increase in [Ca2+]i.. Because previous reports did not describe what types of Ca2+ channels are activated by NA in CHO-α1A, ...
Dulbeccos Modified Eagle Medium:Nutrient Mixture F-12 (DMEM / F-12) is a widely used basal medium for supporting the growth of many different mammalian cells. Cells successfully cultured in DMEM / F-12 include MDCK, glial cells, fibroblasts, human endothelial cells, and rat fibroblasts. Creative Bioarray offers a variety of DMEM / F-12 modifications for a range of cell culture applications ...
Pakistan conferred its top civilian award, the Nishan-e-Pakistan on Chinese President Xi Jinping on Tuesday, for his outstanding contribution in the promotion of the relationship between the two countries.
Fiber and Swann observed significant increments in neuronal Fos-IR in both the MOB and the AOB of male hamsters 1 h after exposure to female hamster vaginal
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Substrate effects on the activation kinetics of Chinese hamster dihydrofolate reductase by p-chloromercuribenzoate (pCMB) have been studied. On the basis of the kinetic equation of substrate reaction in the presence of pCMB, all modification kinetic constants for the free enzyme and enzyme-substrate binary and ternary complexes have been determined. The results of the present study indicate that the modification of Chinese hamster dihydrofolate reductase by pCMB shows single-phase kinetics, and that changes in the enzyme activity and tertiary structure proceed simultaneously during the modification process. Both substrates, NADPH and 7,8-dihydrofolate, protect dihydrofolate reductase against modification by pCMB. In the presence of a saturating concentration of NADPH, the value of kcat for 7,8-dihydrofolate in the enzyme-catalysed reaction increased four-fold on modification of Cys-6, accompanied by a two-fold increase in Km for the modified enzyme. The utilization of the binding energy of a ...
TY - JOUR. T1 - Erythropoietin fails to reverse the anemia in mice continuously exposed to tumor necrosis factor-alpha in vivo. AU - Clibon, U.. AU - Bonewald, Lynda. AU - Caro, J.. AU - Roodman, G. David. PY - 1990. Y1 - 1990. N2 - Tumor necrosis factor-α (TNF) is a monokine produced by activated macrophages that has cytotoxic and cytostatic effects on erythroid progenitor cells. We have recently shown that Chinese hamster ovary cells transfected with the human TNF gene and which constitutively express TNF induced a hypoproliferative anemia, mild thrombocytopenia, and mild leukocytosis when injected into nude mice. We have used this murine model to determine if treatment with recombinant human erythropoietin can prevent or ameliorate the anemia seen with long-term continuous exposure to high concentrations of TNF. Mice bearing TNF-producing tumors became anemic with hematocrits ranging from 30 to 32%. Treatment with recombinant human erythropoietin (100-1000 U/kg body weight three times per ...
TY - JOUR. T1 - Ecto-ganglioside-sialidase activity of herpes simplex virus-transformed hamster embryo fibroblasts. AU - Schengrund, Cara Lynne. AU - Rosenberg, Abraham. AU - Repman, Mary Ann. PY - 1976/9/1. Y1 - 1976/9/1. N2 - Cellular location of ganglioside-sialidase activity was determined in confluent hamster embryo fibroblasts transformed with herpes simplex virus type 2. Approximately equal specific activities of ganglioside-sialidase activity were found to be associated with the crude lysosomal and crude plasma membrane fractions isolated from whole cell homogenates. Whole transformed cells hydrolyzed exogenous ganglioside substrate, suggesting a partial location of the cellular sialidase on the outer surface of the plasma membrane of these cells. Intact cells were treated with the diazonium salt of sulfanilic acid, a nonpenetrating reagent inhibitory to ecto-enzymes (DePierre, J. W., and M. L. Kamovsky. 1974. J. Biol. Chem. 249: 7111-7120). Cytoplasmic lactate dehydrogenase activity was ...
Play media Syrian hamsters (Mesocricetus auratus) are one of several rodents used in animal testing. Syrian hamsters are used to model human medical conditions including various cancers, metabolic diseases, non-cancer respiratory diseases, cardiovascular diseases, infectious diseases, and general health concerns. In 2014, Syrian hamsters accounted for 14.6% of the total animal research participants in the United States covered by the Animal Welfare Act. Since 1972 the use of hamsters in animal testing research has declined. In 2014 in the United States, animal research used about 120,000 hamsters, which was 14.6% of the total research animal use (under the Animal Welfare Act which excludes mice, rats and fish) for that year in that country. According to the Canadian Council for Animal Care, a total of 1,931 hamsters were used for research in 2013 in Canada, making them the sixth-most popular rodent after mice (1,233,196), rats (228,143), guinea pigs (20,687), squirrels (4,446) and voles (2,457). ...
Abstract Thirty male Syrian golden hamsters were each infected with 100 metacercariae of Opisthorchis viverrini. The hamsters were killed at 3, 7, 15, 30, 45, and 154 days of infection. The early pathological changes consisted of an acute inflammatory reaction involving the bile ducts of the second order and the portal connective tissue, especially the large veins, as well as focal coagulation necrosis of the liver lobules. As the flukes developed into adults they induced hyperplasia and adenomatous formations of the bile duct epithelium. There was also a granulomatous response to the adult flukes and eggs. Resolution of the granulomas led to periductal and portal scarring. These findings suggest that immunopathologic mechanisms may be important in the pathogenesis of liver fluke disease.
The distribution of acetylated isoforms of histone H4 along Chinese hamster chromosomes has been studied by immunostaining with antibodies recognizing H4 acetylated at defined lysines in its N-terminal domain. The heterochromatic long arm of the X chromosome in both female (CHO) and male (DON) cell lines is underacetylated at three out of four lysines (5, 8, and 12). In contrast, the level of acetylation at lysine 16, which is the first to be acetylated in mammals, was similar in X chromosomes and autosomes. Labeling of the cells with bromodeoxyuridine (BrdU) to mark late-replicating chromosome domains, followed by double immunostaining with antibodies to BrdU and acetylated H4, showed a close, though not perfect, correlation between late replication and low levels of H4 acetylation. The results show that levels of histone acetylation are associated with the replication timing of defined domains on both the X chromosome and autosomes, but the exceptions we observe suggest that this link is not absolute
Read "Interactions between Impermeant Blocking Ions in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore: Evidence for Anion-Induced Conformational Changes, The Journal of Membrane Biology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Results for Cricetinae - Research Portal | Lancaster UniversityResults for Cricetinae - Research Portal | Lancaster University

Results for Cricetinae. Publications & Outputs. *. Time-resolved and two-photon emission imaging microscopy of live cells with ...
more infohttp://www.research.lancs.ac.uk/portal/en/browse.html?from=publications&word=Cricetinae

European hamster - WikipediaEuropean hamster - Wikipedia

The common hamster is a nocturnal or crepuscular species. It lives in a complex burrow system. It eats seeds, legumes, root vegetables, grasses and insects. It transports its food in its elastic cheek pouches to the food storage chambers. These may be quite large and may consist of a total of 65 kg of food.[9] It hibernates between October and March. During this time, it wakes every five to seven days to feed from the storage chambers. The adults reach sexual maturity when they are about 43 days old and breed from early April to August. The gestation period is 18-20 days and the size of the litter ranges from three to 15 young, which are weaned when aged three weeks. They are usually solitary animals.[9] ...
more infohttps://en.wikipedia.org/wiki/European_hamster

List of mammals of Greece - WikipediaList of mammals of Greece - Wikipedia

Subfamily: Cricetinae *Genus: Cricetulus *Grey dwarf hamster Cricetulus migratorius LR/nt. *Subfamily: Arvicolinae *Genus: ...
more infohttps://en.wikipedia.org/wiki/List_of_mammals_of_Greece

Category:Phodopus sungorus - Wikimedia CommonsCategory:Phodopus sungorus - Wikimedia Commons

Cricetinae • Genus: Phodopus • Species: Phodopus sungorus (Pallas, 1773) ...
more infohttps://commons.wikimedia.org/wiki/Category:Phodopus_sungorus

BioModels DatabaseBioModels Database

Cricetinae (1). Cricetulus griseus (1). Cryptococcus neoformans (1). Danio rerio (1). Debaryomyces hansenii (1). ...
more infohttps://www.ebi.ac.uk/biomodels-main/taxonomy

RCSB PDB - 4JYU: Structure of factor VIIA in complex with the inhibitor (2R)-2-[(1-AMINOISOQUINOLIN-6-YL)AMINO]-2-[3-ETHOXY-4-...RCSB PDB - 4JYU: Structure of factor VIIA in complex with the inhibitor (2R)-2-[(1-AMINOISOQUINOLIN-6-YL)AMINO]-2-[3-ETHOXY-4-...

Expression System: Cricetinae. *Deposited: 2013-04-01 Released: 2013-07-24 *Deposition Author(s): Wei, A., Anumula, R. ...
more infohttps://www.rcsb.org/structure/4JYU

RCSB PDB - 4JZE: Structure of factor VIIA in complex with the inhibitor 2-{2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6...RCSB PDB - 4JZE: Structure of factor VIIA in complex with the inhibitor 2-{2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6...

Expression System: Cricetinae. *Deposited: 2013-04-02 Released: 2013-08-21 *Deposition Author(s): Wei, A., Anumula, R. ...
more infohttps://www.rcsb.org/structure/4JZE

PDB 1oqg structure summary ‹ Protein Data Bank in Europe (PDBe) ‹ EMBL-EBIPDB 1oqg structure summary ‹ Protein Data Bank in Europe (PDBe) ‹ EMBL-EBI

Expression system: Cricetinae gen. sp.. UniProt: *Canonical: P02787 (Residues: 20-354; Coverage: 49%) ...
more infohttp://www.ebi.ac.uk/pdbe/entry/pdb/1OQG

Imunidade inata e imunopatogenia nas leishmanioses experimentais.Imunidade inata e imunopatogenia nas leishmanioses experimentais.

Cricetinae. Disease models animal. Dogs. Immunity natural/immunology. Insulin-like growth factor I. Leishmaniasis/immunology. ...
more infohttp://www.teses.usp.br/teses/disponiveis/livredocencia/5/tde-20032009-105226/pt-br.php

In vitro import of peroxisome-targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes.In vitro import of peroxisome-targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes.

Cricetinae. Cricetulus. Liver / cytology, metabolism. Multiprotein Complexes / metabolism. Peroxisomes / metabolism*. Rats. ...
more infohttp://www.biomedsearch.com/nih/In-vitro-import-peroxisome-targeting/19264098.html

De novo derivation of proteomes from transcriptomes for transcript and protein identification.De novo derivation of proteomes from transcriptomes for transcript and protein identification.

Cricetinae. Cricetulus. Databases, Protein. HeLa Cells. Humans. Lysine / metabolism. Nitrogen Isotopes. Nuclear Proteins / ...
more infohttp://www.biomedsearch.com/nih/De-novo-derivation-proteomes-from/23142869.html

UniProt: G3HQV8 CRIGRUniProt: G3HQV8 CRIGR

Cricetinae; Cricetulus. OX NCBI_TaxID=10029 {ECO:0000313,EMBL:EGW00832.1, ECO:0000313,Proteomes:UP000001075}; RN [1] {ECO: ...
more infohttp://www.genome.jp/dbget-bin/www_bget?uniprot:G3HQV8_CRIGR

UniProt: G3IIK0 CRIGRUniProt: G3IIK0 CRIGR

Cricetinae; Cricetulus. OX NCBI_TaxID=10029 {ECO:0000313,EMBL:EGW13235.1, ECO:0000313,Proteomes:UP000001075}; RN [1] {ECO: ...
more infohttp://www.genome.jp/dbget-bin/www_bget?uniprot:G3IIK0_CRIGR

Tscherskia - WikispeciesTscherskia - Wikispecies

Subfamilia: Cricetinae Genus: Tscherskia. Species: T. triton Name[edit]. Tscherskia (Ognev, 1914) ...
more infohttps://species.wikimedia.org/wiki/Tscherskia

Muroideos - Wikipedia, a enciclopedia libreMuroideos - Wikipedia, a enciclopedia libre

A dos muroideos (Muroidea) é unha gran superfamilia de roedores da suborde dos miomorfos. Inclúe os hámsteres, xerbos, ratos e ratas, e moitos outros parentes, que ocupan unha vastísima variedade de hábitats en todos os continentes excepto a Antártida. Algunhas autoridades colocaron a todos os membros deste grupo nunha soa familia, a dos múridos, debido ás dificultades para determinar como as diferentes subfamilias se relacionan entre si. ...
more infohttps://gl.wikipedia.org/wiki/Muroideos

쥐상과 - 위키백과, 우리 모두의 백과사전쥐상과 - 위키백과, 우리 모두의 백과사전

Norris, R. W.; Zhou, K. Y.; Zhou, C. Q.; Yang, G.; Kilpatrick, C. W.; Honeycutt, R. L. (2004), "The phylogenetic position of the zokors (Myospalacinae) and comments on the families of muroids (Rodentia)", 》Molecular Phylogenetics and Evolution》 31 (3): 972-978, PMID 15120394, doi:10.1016/j.ympev.2003.10.020 ...
more infohttps://ko.wikipedia.org/wiki/%EC%A5%90%EC%83%81%EA%B3%BC

SIA Acc. 09-005, National Museum of Natural History (U.S.) Division of Mammals, Correspondence, c. 1965-2001 | Smithsonian...SIA Acc. 09-005, National Museum of Natural History (U.S.) Division of Mammals, Correspondence, c. 1965-2001 | Smithsonian...

The Smithsonian Institution Archives is using Constant Contact, a third-party contact management software vendor, to manage contacts and send eNewsletters. Please be advised that Constant Contacts Privacy Statement and Terms and Conditions apply to your use of these services. The Smithsonian Institution Archives has access to your name and email address which is subject to our privacy statement. ...
more infohttps://siarchives.si.edu/collections/siris_arc_282588

Hypoxia-selective antitumor agents. 4. Relationships between structure, physicochemical properties, and hypoxia-selective...Hypoxia-selective antitumor agents. 4. Relationships between structure, physicochemical properties, and hypoxia-selective...

Cricetinae. *Nitracrine (analogs & derivatives) *Structure-Activity Relationship. Join CureHunter, for free Research Interface ...
more infohttp://www.curehunter.com/public/pubmed2329552.do

Fluoroquinolones: antimicrobial activity and chemotherapeutic efficacy with respect to various pathogens in highly dangerous...Fluoroquinolones: antimicrobial activity and chemotherapeutic efficacy with respect to various pathogens in highly dangerous...

Cricetinae. *Fluoroquinolones (pharmacology, therapeutic use) *Francisella tularensis (drug effects) *Glanders (drug therapy, ...
more infohttp://www.curehunter.com/public/pubmed19275053.do

Hamster Immune Responses in Infectious and Oncologic Diseases | SpringerLinkHamster Immune Responses in Infectious and Oncologic Diseases | SpringerLink

Comparative Immunology of Old World Hamsters -- Cricetinae John E. Coe. Pages 95-101 ...
more infohttps://link.springer.com/book/10.1007/978-1-4757-0495-2
  • The genus Phodopus is one of three well-supported lineages in Cricetinae, the other two being the genus Mesocricetus and the Cricetus-related group (Cricetus, Tscherskia, Allocricetulus, and Cricetulus). (wikipedia.org)
  • Phodopus is sister to all other Cricetinae (meaning that it is the first lineage to diverge in the clade). (wikipedia.org)
  • The system of hamsters (Cricetinae) in the sphere of the world fauna and their phylogenetic relations] (in Russian). (wikimedia.org)
  • Phodopus campbelli ) is in sûchdier út it skift fan 'e kjifdieren ( Rodentia ), de famylje fan 'e wrotmûseftigen ( Cricetidae ), de ûnderfamylje fan 'e hamsters ( Cricetinae ) en it skaai fan 'e dwerchhamsters ( Phodopus ), dat foarkomt yn Sintraal-Aazje , súdlik Sibearje en dielen fan East-Aazje . (wikipedia.org)
  • Yn parten fan Mongoalje diele se soms in hoale mei soarten gerbilrotten fan it skaai Meriones , en yn Tûva wenje se wol yn by oare soarten hamsters , lykas de Sineeske dwerchhamster ( Cricetulus griseus ), de woastyndwerchhamster ( Phodopus roborovskii ) of de langsturtdwerchhamster ( Cricetulus longicaudatus ). (wikipedia.org)