Cresols, also known as hydroxytoluene, are a group of phenolic compounds including ortho-cresol, meta-cresol, and para-cresol, which differ in the position of the hydroxyl group on the benzene ring.
A non-crystalline form of silicon oxide that has absorptive properties. It is commonly used as a desiccating agent and as a stationary phase for CHROMATOGRAPHY. The fully hydrated form of silica gel has distinct properties and is referred to as SILICIC ACID.
Red dye, pH indicator, and diagnostic aid for determination of renal function. It is used also for studies of the gastrointestinal and other systems.
A group of 1,2-benzenediols that contain the general formula R-C6H5O2.
Organic esters or salts of sulfonic acid derivatives containing an aliphatic hydrocarbon radical.
Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.
An antiseptic and disinfectant aromatic alcohol.
Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.
Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.

Skeletal muscle type ryanodine receptor is involved in calcium signaling in human B lymphocytes. (1/423)

The regulation of intracellular free Ca2+ concentration ([Ca2+]i) in B cells remains poorly understood and is presently explained almost solely by inositol 1,4,5-triphosphate (IP3)-mediated Ca2+ release, followed by activation of a store-operated channel mechanism. In fact, there are reports indicating that IP3 production does not always correlate with the magnitude of Ca2+ release. We demonstrate here that human B cells express a ryanodine receptor (RYR) that functions as a Ca2+ release channel during the B cell antigen receptor (BCR)-stimulated Ca2+ signaling process. Immunoblotting studies showed that both human primary CD19(+) B and DAKIKI cells express a 565-kDa immunoreactive protein that is indistinguishable in molecular size and immunoreactivity from the RYR. Selective reverse transcription-polymerase chain reaction, restriction fragment length polymorphism, and sequencing of cloned cDNA indicated that the major isoform of the RYR expressed in primary CD19(+) B and DAKIKI cells is identical to the skeletal muscle type (RYR1). Saturation analysis of [3H]ryanodine binding yielded Bmax = 150 fmol/mg of protein and Kd = 110 nM in DAKIKI cells. In fluo-3-loaded CD19(+) B and DAKIKI cells, 4-chloro-m-cresol, a potent activator of Ca2+ release mediated by the ryanodine-sensitive Ca2+ release channel, induced Ca2+ release in a dose-dependent and ryanodine-sensitive fashion. Furthermore, BCR-mediated Ca2+ release in CD19(+) B cells was significantly altered by 4-chloro-m-cresol and ryanodine. These results indicate that RYR1 functions as a Ca2+ release channel during BCR-stimulated Ca2+ signaling and suggest that complex Ca2+ signals that control the cellular activities of B cells may be generated by cooperation of the IP3 receptor and RYR1.  (+info)

Tolterodine does not affect the human in vivo metabolism of the probe drugs caffeine, debrisoquine and omeprazole. (2/423)

AIM: To investigate the in vivo effect of treatment with tolterodine on debrisoquine 4-hydroxylation (an index of CYP2D6 activity), omeprazole 5-hydroxylation (CYP2C19), omeprazole sulphoxidation (CYP3A4) and caffeine N3-demethylation (CYP1A2). METHODS: Twelve healthy male volunteers (eight extensive metabolisers [EMs] and four poor metabolisers [PMs] with respect to CYP2D6) received 4 mg tolterodine L-tartrate orally twice daily for 6 days. All subjects were EMs with respect to CYP2C19. The subjects received single oral doses of debrisoquine (10 mg), omeprazole (20 mg) and caffeine (100 mg) for determination of the appropriate metabolic ratios (MR). The drugs were given on separate consecutive days, before, during and after the co-administration of tolterodine. RESULTS: Mean serum tolterodine concentrations were 5-10 times higher in PMs than in EMs. Serum concentrations of the active 5-hydroxymethyl metabolite of tolterodine, 5-HM, were not quantifiable in PMs. The mean MR of debrisoquine (95% confidence interval) during tolterodine treatment was 0.50 (0.25-0.99) and did not differ statistically from the values before [0.49 (0.20-1.2)] and after tolterodine administration [0.46 (0.14-1.6)] in EMs. The mean MR of omeprazole hydroxylation and sulphoxidation or caffeine metabolism were not changed in the presence of tolterodine in either EMs or PMs. Debrisoquine and caffeine had no significant effect on the AUC(1,3 h) of either tolterodine or 5-HM, but during omeprazole administration small decreases (13-19%) in these parameters were seen. CONCLUSIONS: Tolterodine, administered at twice the expected therapeutic dosage, did not change the disposition of the probe drugs debrisoquine, omeprazole and caffeine and thus had no detectable effect on the activities of CYPs 2D6, 2C19, 3A4 and 1A2. Alteration of the metabolism of substrates of these enzymes by tolterodine is unlikely to occur.  (+info)

Antimalarial activities of WR-194,965, an alpha-amino-o-cresol derivative. (3/423)

Pilot appraisals of the activities of WR-194,965 and WR-204,165, two closely related o-cresol derivatives (both Mannich bases), in owl monkeys infected with the multidrug-resistant Vietnam Smith strain of Plasmodium falciparum showed that these compounds had similar levels of efficacy. Total course doses effecting 90% cures (CD(90)s) were 27 and 37 mg/kg of body weight for the respective compounds, values almost identical to the CD(90) of mefloquine (a highly promising 4-quinolinemethanol) against infections with the same strain, and the CD(90)s of chloroquine against infections with 4-aminoquinoline-susceptible strains. Expanded studies of the activities of WR-194,965 against infections with the Smith strain of P. falciparum and Vietnam Palo Alto strain of P. vivax, designed to guide projected evaluations in human volunteers, showed: (i) that the activity of this compound was a function of total dose administered, with single doses as effective as the same amount delivered in three or seven successive daily fractions; (ii) that all regimens effected rapid clearance of parasitemia; and (iii) that based on CD(90)s, this agent was twice as active against infections with the Palo Alto strain of P. vivax as against the Smith strain of P. falciparum. These findings, together with results of preclinical pharmacological studies pursued elsewhere, provided support for studies in human volunteers now underway.  (+info)

4-chloro-m-cresol triggers malignant hyperthermia in susceptible swine at doses greatly exceeding those found in drug preparations. (4/423)

BACKGROUND: Chlorocresols are used as preservatives in numerous commercial drugs that have been shown to induce myoplasmic Ca2+ release; the most potent isoform is 4-chloro-m-cresol. The aims of this study were to (1) examine the in vivo effects of 4-chloro-m-cresol on swine susceptible to malignant hyperthermia and (2) contrast in vivo versus in vitro dose-response curves. METHODS: Susceptible swine (weight: 38.5 kg+/-3.55 kg) were anesthetized and monitored for variations in physiological responses, including end-tidal CO2, heart rate, blood pressure, blood chemistry, and temperatures. In the first animals studied, 4-chloro-m-cresol, at equivalent cumulative doses of 0.14, 0.28, 0.57, 1.14, 2.27, 4.54, and 9.08 mg/kg (n = 3; 12.5, 25, 50, 100, 200, 400, and 800 micromol) were administered, and in a second group, larger doses were used: 1.14, 3.41, 7.95, 17.04 (n = 4), and/or 35.22 (n = 1) mg/kg (100, 300, 700, 1,500, and/or 3,100 micromol). For comparison, in vitro rectus abdominis muscle preparations obtained from normal and susceptible swine were exposed to 4-chloro-m-cresol, at cumulative concentrations of 6.25, 12.5, 25, 50, 100, 200, 400, 800, and 1,600 micromol; standard caffeine and halothane contracture testing was also performed. RESULTS: Episodes of malignant hyperthermia were not triggered in response to administration of low doses of 4-chloro-m-cresol, but transient cardiovascular reactions (e.g., tachycardia, arrhythmias, and hypotension) were observed. Subsequently, episodes in these animals were triggered when halothane (0.87; 1 MAC) and succinylcholine (2 mg/kg) were given. Animals administered the higher doses of 4-chloro-m-cresol all had fulminant episodes of malignant hyperthermia that were fatal, when equivalent cumulative concentrations were greater than 1,500 micromol. The levels of 4-chloro-m-cresol in the plasma rapidly decreased: e.g., 5 min postadministration of the 1,500-micromol dose, the mean plasma level was only 52+/-18 micromol (n = 4). Hemolysis was detected following 4-chloro-m-cresol administration at concentrations > 200 micromol. In vitro, muscle from susceptible animals elicited contractures > 200 mg at 50-micromol bath concentrations of 4-chloro-m-cresol (n = 29), whereas normal muscle did not elicit such contractures until bath concentrations were > 800 micromol (n = 10). CONCLUSIONS: 4-chloro-m-cresol is a trigger of malignant hyperthermia in susceptible swine, but only when serum concentrations are far above those likely to be encountered in humans. A relatively low concentration of 4-chloro-m-cresol, 50 micromol, is sufficient to activate sarcoplasmic [Ca+2] release in vitro (e.g., contractures); this same bolus dose administered in vivo (0.57 mg/kg) has minimal effects due to the rapid decrease in its plasma levels.  (+info)

4-chloro-m-cresol is a trigger of malignant hyperthermia in susceptible swine. (5/423)

BACKGROUND: 4-Chloro-m-cresol (4-CmC) induces marked contractures in skeletal muscle specimens from individuals susceptible to malignant hyperthermia (MHS). In contrast, 4-CmC induces only small contractures in specimens from normal (MHN) patients. 4-CmC is a preservative within a large number of commercially available drug-preparations (e.g., insulin, heparin, succinylcholine), and it has been suggested that 4-CmC might trigger malignant hyperthermia. This study was designed to investigate the effects of 4-CmC in vivo and in vitro in the same animals. METHODS: After approval of the animal care committee, six Pietrain MHS and six control (MHN) swine were anesthetized with azaperone 4 mg/kg intramuscularly and metomidate 10 mg/kg intraperitoneally. After endotracheal intubation, lungs were mechanically ventilated (inspired oxygen fraction 0.3) and anesthesia was maintained with etomidate 2.5 mg x kg(-1) x h(-1) and fentanyl 50 microg x kg(-1) x h(-1). Animals were surgically prepared with arterial and central venous catheters for measurement of hemodynamic parameters and to obtain blood samples. Before exposure to 4-CmC in vivo, muscle specimens were excised for in vitro contracture tests with 4-CmC in concentrations of 75 and 200 microM. Subsequently, pigs were exposed to cumulative administration of 3, 6, 12, 24, and 48 mg/kg 4-CmC intravenously. If an unequivocal episode of malignant hyperthermia occurred, as indicated by venous carbon dioxide concentration > or = 70 mmHg, pH < or = 7.25, and an increase of temperature > or = 2 degrees C, the animals were treated with dantrolene, 3.5 mg/kg. RESULTS: All MHS swine developed malignant hyperthermia after administration of 4-CmC in doses of 12 or 24 mg/kg. Venous carbon dioxide concentration significantly increased and pH significantly decreased. Temperature increased in all MHS animals more than 2 degrees C. Blood lactate concentrations and creatine kinase levels were significantly elevated. All MHS swine were treated successfully with dantrolene. In contrast, no MHN swine developed signs of malignant hyperthermia. After receiving 4-CmC in a concentration of 48 mg/kg, however, all MHN animals died by ventricular fibrillation. The in vitro experiments showed that both concentrations of 4-CmC produced significantly greater contractures in MHS than in MHN specimens. CONCLUSIONS: 4-CmC is in vivo a trigger of malignant hyperthermia in swine. However, the 4-CmC doses required for induction of malignant hyperthermia were between 12 and 24 mg/kg, which is about 150-fold higher than the 4-CmC concentrations within clinically used preparations.  (+info)

Analysis of alpha 1L-adrenoceptor pharmacology in rat small mesenteric artery. (6/423)

1. To illuminate the controversy on alpha 1A- or alpha 1L-adrenoceptor involvement in noradrenaline-mediated contractions of rat small mesenteric artery (SMA), we have studied the effects of subtype-selective alpha 1-adrenoceptor agonists and antagonists under different experimental conditions. 2. The agonist potency order in rat SMA was: A61603 >> SKF89748-A > cirazoline > noradrenaline > ST-587 > methoxamine. Prazosin antagonized all agonists with a low potency (pA2: 8.29-8.80) indicating the involvement of alpha 1L-rather than alpha 1A-adrenoceptors. 3. The putative alpha 1L-adrenoceptor antagonist JTH-601, but not the alpha 1B-adrenoceptor antagonist chloroethylclonidine (10 microM) antagonized noradrenaline-induced contractions of SMA. The potency of the selective alpha 1D-adrenoceptor antagonist BMY 7378 against noradrenaline (pA2 = 6.16 +/- 0.13) and of the selective alpha 1A-adrenoceptor antagonist RS-17053 against noradrenaline (pKB = 8.35 +/- 0.10) and against the selective alpha 1A-adrenoceptor agonist A-61603 (pKB = 8.40 +/- 0.09) were too low to account for alpha 1D- and alpha 1A-adrenoceptor involvement. 4. The potency of RS-17053 (pKB/pA2's = 7.72-8.46) was not affected by lowering temperature, changing experimental protocol or inducing myogenic tone via KCl or U46619. 5. Selective protection of a putative alpha 1A-adrenoceptor population against the irreversible action of phenoxybenzamine also failed to increase the potency of RS-17053 (pA2 = 8.25 +/- 0.06 against A61603). 6. Combined concentration-ratio analysis demonstrated that tamsulosin, which does not discriminate between alpha 1A- and alpha 1L-adrenoceptors, and RS-17053 competed for binding at the same site in the SMA. 7. In summary, data obtained in our experiments in rat SMA indicate that the alpha 1-adrenoceptor mediating noradrenaline-induced contraction displays a distinct alpha 1L-adrenoceptor pharmacology. This study does not provide evidence for the hypothesis that alpha 1L-adrenoceptors represent an affinity state of the alpha 1A-adrenoceptor in functional assays. Furthermore, there is no co-existing alpha 1A-adrenoceptor in the SMA.  (+info)

Intracellular Ca2+ transients in mouse soleus muscle after hindlimb unloading and reloading. (7/423)

The objective of this study was to determine whether altered intracellular Ca(2+) handling contributes to the specific force loss in the soleus muscle after unloading and/or subsequent reloading of mouse hindlimbs. Three groups of female ICR mice were studied: 1) unloaded mice (n = 11) that were hindlimb suspended for 14 days, 2) reloaded mice (n = 10) that were returned to their cages for 1 day after 14 days of hindlimb suspension, and 3) control mice (n = 10) that had normal cage activity. Maximum isometric tetanic force (P(o)) was determined in the soleus muscle from the left hindlimb, and resting free cytosolic Ca(2+) concentration ([Ca(2+)](i)), tetanic [Ca(2+)](i), and 4-chloro-m-cresol-induced [Ca(2+)](i) were measured in the contralateral soleus muscle by confocal laser scanning microscopy. Unloading and reloading increased resting [Ca(2+)](i) above control by 36% and 24%, respectively. Although unloading reduced P(o) and specific force by 58% and 24%, respectively, compared with control mice, there was no difference in tetanic [Ca(2+)](i). P(o), specific force, and tetanic [Ca(2+)](i) were reduced by 58%, 23%, and 23%, respectively, in the reloaded animals compared with control mice; however, tetanic [Ca(2+)](i) was not different between unloaded and reloaded mice. These data indicate that although hindlimb suspension results in disturbed intracellular Ca(2+) homeostasis, changes in tetanic [Ca(2+)](i) do not contribute to force deficits. Compared with unloading, 24 h of physiological reloading in the mouse do not result in further changes in maximal strength or tetanic [Ca(2+)](i).  (+info)

Sarcoplasmic reticulum Ca(2+) release by 4-chloro-m-cresol (4-CmC) in intact and chemically skinned ferret cardiac ventricular fibers. (8/423)

The purpose of this study was to determine whether 4-chloro-m-cresol (4-CmC) could generate caffeine-like responses in ferret cardiac muscle. The concentration dependence of 4-CmC-mediated release of Ca(2+) from the sarcoplasmic reticulum was studied in intact cardiac trabeculae and saponin-skinned fibers in which the sarcoplasmic reticulum was loaded with Ca(2+). In intact and saponin-skinned preparations isolated from right ventricle, the effect of 4-CmC on sarcoplasmic reticulum Ca(2+) content was estimated by analysis of caffeine contracture after application of chlorocresol. In addition, the effects of 4-CmC on maximal Ca(2+)-activated tension and the Ca(2+) sensitivity of myofibrils were analyzed by using Triton-skinned cardiac fibers. The results show that 4-CmC generates a contractile response in saponin-skinned but not intact fibers. The sarcoplasmic reticulum is implicated in the 4-CmC response; more precisely, in Ca(2+) release via the ryanodine receptor. Moreover, 4-CmC, like caffeine, has effects on maximal Ca(2+)-activated tension and the Ca(2+) sensitivity of myofibrils.  (+info)

Cresols are a group of chemical compounds that are phenolic derivatives of benzene, consisting of methyl substituted cresidines. They have the formula C6H4(OH)(\_3CH3). There are three isomers of cresol, depending on the position of the methyl group: ortho-cresol (m-cresol), meta-cresol (p-cresol), and para-cresol (o-cresol). Cresols are used as disinfectants, antiseptics, and preservatives in various industrial and commercial applications. They have a characteristic odor and are soluble in alcohol and ether. In medical terms, cresols may be used as topical antiseptic agents, but they can also cause skin irritation and sensitization.

Silica gel is not typically considered a medical term, but it is often used in medical contexts. Silica gel is a form of silicon dioxide (SiO2), which is a naturally occurring mineral. It is usually produced in a porous form, with a large surface area and high absorption capacity.

In the medical field, silica gel is sometimes used as a desiccant in packaging to protect sterile medical supplies from moisture during storage and transportation. This helps maintain the sterility of the products and ensures their effectiveness when they are used. Silica gel can also be found in some medical devices, such as wound dressings, where it can help absorb excess exudate and maintain a moist environment that promotes healing.

It is important to note that silica gel should not be ingested or inhaled, as it can cause irritation to the respiratory and gastrointestinal tracts.

Phenolsulfonphthalein (PSP) is a chemical compound that has been historically used in medicine as a diagnostic test for kidney function. It's an acid-base indicator, which means it changes color depending on the pH of the solution it's in. In its colored form, PSP is pink, and in its uncolored form, it's colorless.

In the context of renal function testing, PSP is given to a patient orally or intravenously, and then its clearance from the body is measured through urine and blood samples. The rate at which PSP is cleared from the body can provide information about the glomerular filtration rate (GFR), which is an important indicator of kidney function. However, this test has largely been replaced by more modern and accurate methods for measuring GFR.

It's worth noting that phenolsulfonphthalein is not a medication or therapeutic agent, but rather a diagnostic tool that has been used in the past to assess kidney function.

Catechols are a type of chemical compound that contain a benzene ring with two hydroxyl groups (-OH) attached to it in the ortho position. The term "catechol" is often used interchangeably with "ortho-dihydroxybenzene." Catechols are important in biology because they are produced through the metabolism of certain amino acids, such as phenylalanine and tyrosine, and are involved in the synthesis of various neurotransmitters and hormones. They also have antioxidant properties and can act as reducing agents. In chemistry, catechols can undergo various reactions, such as oxidation and polymerization, to form other classes of compounds.

Alkanesulfonates are organic compounds that consist of a hydrocarbon chain, typically consisting of alkane molecules, which is bonded to a sulfonate group. The sulfonate group (-SO3-) consists of a sulfur atom bonded to three oxygen atoms, with one of the oxygen atoms carrying a negative charge.

Alkanesulfonates are commonly used as detergents and surfactants due to their ability to reduce surface tension and improve the wetting, emulsifying, and dispersing properties of liquids. They are also used in various industrial applications, such as in the production of paper, textiles, and leather.

In medical terms, alkanesulfonates may be used as topical antimicrobial agents or as ingredients in personal care products. However, some alkanesulfonates have been found to have potential health and environmental hazards, such as irritation of the skin and eyes, respiratory effects, and potential toxicity to aquatic life. Therefore, their use is subject to regulatory oversight and safety assessments.

Adipates are a group of chemical compounds that are esters of adipic acid. Adipic acid is a dicarboxylic acid with the formula (CH₂)₄(COOH)₂. Adipates are commonly used as plasticizers in the manufacture of polyvinyl chloride (PVC) products, such as pipes, cables, and flooring. They can also be found in cosmetics, personal care products, and some food additives.

Adipates are generally considered to be safe for use in consumer products, but like all chemicals, they should be used with caution and in accordance with recommended guidelines. Some adipates have been shown to have potential health effects, such as endocrine disruption and reproductive toxicity, at high levels of exposure. Therefore, it is important to follow proper handling and disposal procedures to minimize exposure.

Phenol, also known as carbolic acid, is an organic compound with the molecular formula C6H5OH. It is a white crystalline solid that is slightly soluble in water and has a melting point of 40-42°C. Phenol is a weak acid, but it is quite reactive and can be converted into a variety of other chemicals.

In a medical context, phenol is most commonly used as a disinfectant and antiseptic. It has a characteristic odor that is often described as "tarry" or " medicinal." Phenol is also used in some over-the-counter products, such as mouthwashes and throat lozenges, to help kill bacteria and freshen breath.

However, phenol is also a toxic substance that can cause serious harm if it is swallowed, inhaled, or absorbed through the skin. It can cause irritation and burns to the eyes, skin, and mucous membranes, and it can damage the liver and kidneys if ingested. Long-term exposure to phenol has been linked to an increased risk of cancer.

Because of its potential for harm, phenol is regulated as a hazardous substance in many countries, and it must be handled with care when used in medical or industrial settings.

Phenols, also known as phenolic acids or phenol derivatives, are a class of chemical compounds consisting of a hydroxyl group (-OH) attached to an aromatic hydrocarbon ring. In the context of medicine and biology, phenols are often referred to as a type of antioxidant that can be found in various foods and plants.

Phenols have the ability to neutralize free radicals, which are unstable molecules that can cause damage to cells and contribute to the development of chronic diseases such as cancer, heart disease, and neurodegenerative disorders. Some common examples of phenolic compounds include gallic acid, caffeic acid, ferulic acid, and ellagic acid, among many others.

Phenols can also have various pharmacological activities, including anti-inflammatory, antimicrobial, and analgesic effects. However, some phenolic compounds can also be toxic or irritating to the body in high concentrations, so their use as therapeutic agents must be carefully monitored and controlled.

"Pseudomonas" is a genus of Gram-negative, rod-shaped bacteria that are widely found in soil, water, and plants. Some species of Pseudomonas can cause disease in animals and humans, with P. aeruginosa being the most clinically relevant as it's an opportunistic pathogen capable of causing various types of infections, particularly in individuals with weakened immune systems.

P. aeruginosa is known for its remarkable ability to resist many antibiotics and disinfectants, making infections caused by this bacterium difficult to treat. It can cause a range of healthcare-associated infections, such as pneumonia, bloodstream infections, urinary tract infections, and surgical site infections. In addition, it can also cause external ear infections and eye infections.

Prompt identification and appropriate antimicrobial therapy are crucial for managing Pseudomonas infections, although the increasing antibiotic resistance poses a significant challenge in treatment.

Oxygenases are a class of enzymes that catalyze the incorporation of molecular oxygen (O2) into their substrates. They play crucial roles in various biological processes, including the biosynthesis of many natural products, as well as the detoxification and degradation of xenobiotics (foreign substances).

There are two main types of oxygenases: monooxygenases and dioxygenases. Monooxygenases introduce one atom of molecular oxygen into a substrate while reducing the other to water. An example of this type of enzyme is cytochrome P450, which is involved in drug metabolism and steroid hormone synthesis. Dioxygenases, on the other hand, incorporate both atoms of molecular oxygen into their substrates, often leading to the formation of new carbon-carbon bonds or the cleavage of existing ones.

It's important to note that while oxygenases are essential for many life-sustaining processes, they can also contribute to the production of harmful reactive oxygen species (ROS) during normal cellular metabolism. An imbalance in ROS levels can lead to oxidative stress and damage to cells and tissues, which has been linked to various diseases such as cancer, neurodegeneration, and cardiovascular disease.

There are three forms (isomers) of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol). These ... Dihydroxytoluene Trihydroxytoluene o-CRESOL (ICSC) m-CRESOL (ICSC) p-CRESOL (ICSC) Pubchem. "o-cresol". pubchem.ncbi.nlm.nih. ... Another isomer of cresol is called Benzyl alcohol, or alpha-cresol (α-cresol). Benzyl alcohol has a hydroxy group inside a ... W. W. Hartman (1923). "p-Cresol". Organic Syntheses. 3: 37. doi:10.15227/orgsyn.003.0037. Helmut Fiegein "Cresols and Xylenols ...
... does not inhibit Taq polymerase to the same degree as other common loading dyes. Cresol red can also be used as an ... "Cresol red". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-01-25. Cresol Red at OpenWetWare life scientists' wiki (Articles without ... Cresol red (full name: o-cresolsulfonephthalein) is a triarylmethane dye frequently used for monitoring the pH in aquaria. ... Cresol red can be used in many common molecular biology reactions in place of other loading dyes. ...
It is a derivative of phenol and is an isomer of p-cresol and m-cresol. o-Cresol is one of the chemical compounds found in ... Most exposures to cresols are at very low levels that are not harmful although, like phenols, cresols are skin irritants. When ... o-Cresol is a constituent of tobacco smoke. Together with many other compounds, o-cresol is traditionally extracted from coal ... ortho-Cresol (IUPAC name: 2-methylphenol, also known as 2-hydroxytoluene or ortho-Toluenol) is an organic compound with the ...
It is a derivative of phenol and is an isomer of o-cresol and m-cresol. Together with many other compounds, p-cresol is ... p-Cresol is a constituent of tobacco smoke. p-Cresol is a major component in pig odor. Temporal glands secretion examination ... This residue contains a few percent by weight of phenol and cresols. Industrially, p-cresol is currently prepared mainly by a ... W. W. Hartman (1923). "p-Cresol". Organic Syntheses. 3: 37. doi:10.15227/orgsyn.003.0037. "meta- and para-Cresols" (PDF). ...
It is a derivative of phenol and is an isomer of p-cresol and o-cresol. Together with many other compounds, m-cresol is ... m-Cresol is a component found in secretions from the ant Colobopsis saundersi during Autothysis. Cresol NIOSH Pocket Guide to ... This residue contains a few percent by weight of phenol and isomeric cresols. In the cymene-cresol process, toluene is ... meta-Cresol, also 3-methylphenol, is an organic compound with the formula CH3C6H4(OH). It is a colourless, viscous liquid that ...
... (DNOC) is an organic compound with the structural formula CH3C6H2(NO2)2OH. It is a yellow solid that is ... This compound is prepared by disulfonation of o-cresol. The resulting disulfonate is then treated with nitric acid to give DNOC ... Parker, V. H.; Barnes, J. M.; Denz, F. A. (1951). "Some Observations on the Toxic Properties of 3:5-Dinitro-Ortho-Cresol". ... Harvey, DG; Bidstrup, PL; Bonnell, JA (1951). "Poisoning by dinitro-ortho-cresol; some observations on the effects of dinitro- ...
... is a chlorinated cresol. The compound is difficult to synthesise as chlorination of m-cresol yields the para- ... Huston, Ralph C.; Chen, Philip S. (October 1933). "The Chloro Derivatives of m-Cresol". Journal of the American Chemical ...
Other names in common use include p-cresol-(acceptor) oxidoreductase (hydroxylating), and p-cresol methylhydroxylase. This ... McIntire W, Edmondson DE, Singer TP, Hopper DJ (1980). "8α-O-Tyrosyl-FAD: A New Form of Covalently Bound Flavin from p-Cresol ... In enzymology, a 4-cresol dehydrogenase (hydroxylating) (EC 1.17.99.1) is an enzyme that catalyzes the chemical reaction 4- ... Hopper DJ, Taylor DG (1977). "The Purification and Properties of p-cresol-(Acceptor) Oxidoreductase (Hydroxylating), a ...
... at Sigma-Aldrich Fiege, Helmut (2000). "Cresols and Xylenols". Ullmann's Encyclopedia of Industrial Chemistry. doi: ... 2 H2O Challenges associated with the production is the similarity of the boiling points of cresols and this xylenol. 2,6- ... 6-dimethylphenol in a fluidized bed of iron-chromium mixed oxide catalyst with o-cresol circulation" (PDF). Chemistry Central ...
"Cresols and Xylenols". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a08_025. ( ...
Cresols are produced from isopropyltoluene. Crude acetone is hydrogenated in the liquid phase over Raney nickel or a mixture of ...
... "p-Cresol". Organic Syntheses. 3: 37. doi:10.15227/orgsyn.003.0037. (Substitution reactions). ...
W. W. Hartman (1923). "p-Cresol". Organic Syntheses. 3: 37. doi:10.15227/orgsyn.003.0037. (Articles without InChI source, ...
Heating this salt in strong base results in desulfonation, giving, after acid workup, p-cresol. Marc Julia, Michel Maumy (1976 ... W. W. Hartman (1923). "p-Cresol". Organic Syntheses. 3: 37. doi:10.15227/orgsyn.003.0037. (Articles without InChI source, ...
W. W. Hartman (1923). "p-Cresol". Organic Syntheses. 3: 37. doi:10.15227/orgsyn.003.0037.; Collective Volume, vol. 1, p. 175 ...
For industrial applications the chemical is synthesized from p-cresol using aromatic substitution with bromine followed by ... Asim Kumar Mukhopadhyay (2004). Industrial Chemical Cresols and Downstream Derivatives. New York: CRC Press. p. 81. ISBN ...
The EPA has classified o-cresol, m-cresol, and p-cresol as Group C: possible human carcinogens. Exposure to 26% Creolin ... 6-nitro-m-cresol.[citation needed] p-Cresol is used largely in the formulation of antioxidants and in the fragrance and dye ... o-Cresol is used as a solvent, disinfectant, and chemical intermediate.[citation needed] m-Cresol is used to produce certain ... For cresol bactericides or disinfectants the mechanism of action is due to the destruction of bacterial cell membranes. The ...
Earlier formulations of Lysol contained cresol, a compound that can induce abortions, and it was widely used by women who could ... The original formulation of Lysol contained cresols. This formulation may still be available commercially in some parts of the ...
... or m-cresol purple, also called m-cresolsulfonphthalein, is a triarylmethane dye and a pH indicator. It is ... "m-Cresol Purple 857890". Sigma-Aldrich. Retrieved 2017-07-30. Loucaides, Socratis; Rèrolle, Victoire M. C; Papadimitriou, ... "Characterization of meta-Cresol Purple for spectrophotometric pH measurements in saline and hypersaline media at sub-zero ...
Cresol Resin "Sunlight and Firelight , StoryTrax". Archived from the original on 2007-09-29. Retrieved 2007-06-22. "Untitled , ...
It is compounded of phenols such as guaiacol, cresol, xylenol and creosol (not to be confused with cresol). Wood-tar creosote ... cresol and xylenol; the rest being a combination of monophenols and polyphenols. Pitch is a name for any of a number of ...
Silla, ~ El Cresol de (2016-05-26). "Un any d'aprofundiment democràtic a Silla". El Cresol de Silla (in Catalan). Retrieved ...
The majority of the cresol is excreted unchanged in urine; however, some of the p-cresol and o-cresol is excreted as a ... o-Cresol may be a less sensitive marker of toluene exposure than hippuric acid. o-Cresol excretion may be an unreliable method ... Urinary o-cresol may be more reliable for the biomonitoring of toluene exposure because, unlike hippuric acid, o-cresol is not ... CYP2E1 catalyses the formation of benzyl alcohol and p-cresol, while CYP2B6 produces comparatively little p-cresol. It is ...
... p-chloro-m-cresol, chlorothymol, mixed cresols, m-cresol, o-cresol, p-cresol, isopropyl cresols, thymol, o-cymen-5-ol, and ... It has also been prepared by transalkylation of isopropylated cresols. It is extracted from Origanum oil by means of a 50% ... Andersen, A. (2006). "Final report on the safety assessment of sodium p-chloro-m-cresol, ...
Alcohols and hydroperoxides alkylate phenols in the presence of solid acid catalysts (e.g. certain zeolite). Cresols and cumyl ... Bamberger rearrangement Claisen rearrangement Cresol Fries rearrangement Polyphenol "Front Matter". Nomenclature of Organic ...
P-cresol was seen to be the easiest to degrade through the sulfate-enriched environment, while m-cresol and o-cresol where ... Cresol (m-, p-, and o-), phenol, guaiacol, and xylenol (1,3,4- and 1,3,5-) all are acute aquatic hazards[citation needed] prior ... An example of the oxidation of p-cresol and phenol can be seen in the figures below: This reaction shows the oxidation of p- ... Wang F, Yang G, Zhang W, Wu W, Xu J (June 2004). "Oxidation of p-Cresol to p-Hydroxybenzaldehyde with Molecular Oxygen in the ...
Volkova was the first to synthesize para-tricresol phosphate from para-cresol, which is currently used as a plasticizer ... By reacting toluene sulfonic acids with the base, Volkova obtained the corresponding cresols, thereby facilitating the sulfonic ... She was the first chemist to synthesize para-tricresol phosphate from para-cresol, a component of plasticizer. Volkova was the ... Synthesized para-tricresol phosphate from para-cresol; Discovered the structure of toluene sulfonic acids; Discovered that ...
Cresol is used for leathery or medicinal flavoring. Butyraldehyde is used for chocolate flavoring. Isoamyl acetate is used for ... cresol, butyraldehyde, and isoamyl acetate. Sugars are frequently used in e-liquids to provide a sweet flavor. Diacetyl, ...
In place of phenol itself, they are often produced from cresols (methylphenols). The polymerization is brought to completion ...
It can be produced by carboxylation of o-cresol. 4-Methylsalicylic acid 6-Methylsalicylic acid Takayuki Iijima; Tatsuaki ...
Cresols, when breathed at very high levels, may cause irritation of the nose and throat. These chemicals have been found in at ... Exposure to cresols occurs mainly from breathing air containing car exhaust, breathing air from homes heated with coal or wood ... ortho-cresol (o-cresol), meta-cresol (m-cresol, and para-cresol (p-cresol). These forms occur separately or as a mixture. ... o-Cresol, m-cresol, p-cresol, and mixed cresols have been found in at least 210, 22, 310, and 70 of the 1,678 current or former ...
There are three forms (isomers) of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol). These ... Dihydroxytoluene Trihydroxytoluene o-CRESOL (ICSC) m-CRESOL (ICSC) p-CRESOL (ICSC) Pubchem. "o-cresol". pubchem.ncbi.nlm.nih. ... Another isomer of cresol is called Benzyl alcohol, or alpha-cresol (α-cresol). Benzyl alcohol has a hydroxy group inside a ... W. W. Hartman (1923). "p-Cresol". Organic Syntheses. 3: 37. doi:10.15227/orgsyn.003.0037. Helmut Fiegein "Cresols and Xylenols ...
Get information about p-Cresol C7H8O and fitting detectors and PPE. ✓testing, monitoring ✓protective equipment ✓1500+ ... 1-Hydroxy-4-methylbenzene 4-Cresol 4-Hydroxytoluene 4-Methyl-phenol 4-Methylphenol Cresol, para p-cresol p-Cresol (8CI) p- ... Suitable products for p-Cresol C7H8O. Whether portable gas detectors, gas detection tubes or personal protective equipment - ...
... Nominated Substances: 4,4-Thiobis(6-tert-butyl-m-cresol) ... Nomination Summary for Nomination Summary for 4,4-Thiobis(6-tert-butyl-m-cresol) (N80365) ...
How to detect Cresol, o-. Formula: C7H8O , CAS: 95-48-7. Synonyms: 2-methylphenol, ortho-cresol, 2-cresol, o-cresylic acid, 1- ... Cresol, o-. 2-methylphenol, ortho-cresol, 2-cresol, o-cresylic acid, 1-hydroxy-2-methylbenzene, 2-hydroxytoluene, 2-methyl ... View products detecting gaseous Cresol, o-. TVOC 2 Continuous VOC Gas Detector. TVOC 2 is a fixed, continuous VOC gas detector ...
Cresol red changes from yellow to red from pH 7.2 - 8.8. Synonyms and Related Terms. o-cresol-sulfonphthalein; rosso cresolo ( ... Retrieved from "https://cameo.mfa.org/index.php?title=Cresol_red&oldid=29759" ...
It is the first study involving the use of a $p$-cresol probe for the determination of the HOBr scavenging activity of ... While the $p$-cresol probe ($\lambda_{ex}$ = 260 nm, $\lambda_{em}$ = 305 nm) has fluorescence characteristics, its brominated ... The initial fluorescence intensity of the $p$-cresol probe is decreased in the presence of the brominating agent, HOBr, and ... cresol (4-methyl phenol) probe is developed for the measurement of HOBr scavenging activity. ...
O-CRESOL AldrichCPR; CAS Number: 73468-83-4; Linear Formula: C14H14N2O2; find -S689173 MSDS, related peer-reviewed papers, ...
View our Para cresols products at Fisher Scientific. ...
Retrieved from "http://drcspatial.usask.ca/wiki/index.php/Special:FormEdit/Product/Cresols" ...
m-Cresol Purple-1g / Technical Grade / Indicator (Sodium Salt) / Formula: C21H18O5S This is for ideal use in school labs. A ... M-CRESOL PURPLE. $ 212.15. excl. GST. m-Cresol Purple-1g / Technical Grade / Indicator (Sodium Salt) / Formula: C21H18O5S. This ... m-Cresol Purple-1g / Technical Grade / Indicator (Sodium Salt) / Formula: C21H18O5S. This is for ideal use in school labs.. A ...
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... Synonym(s). 2,4-Dinitro-6-methylphenol , 2-Methyl-4,6-dinitrophenol , 3,5-Dinitro-2-hydroxytoluene , 3,5- ... Dinitro-o-cresol , 4,6-Dinitro-2-methylphenol , 6-Methyl-2,4-dinitrophenol , Antinonin , Antinonnin , Arborol , DNOC , ... Degrassan , Dekrysil , Detal , Dillex , Dinitro , Dinitro-o-cresol , Dinitrocresol , Dinitrodendtroxal , Dinitrol , Dinoc , ...
Η παρούσα διπλωματική εργασία εκπονήθηκε με σκοπό τη σύνθεση και το χαρακτηρισμό ζεόλιθου ZSM-5 και τη χρήση του για τον καθαρισμό υδατικών διαλυμάτων από βλαβερές για το περιβάλλον οργανικές ενώσεις μέσω της προσροφητικής ...
Benzotriazolyl dodecyl p-cresol Benzotriazolyl Dodecyl P-Cresol This aromatic derivative is a stabilising agent. It protects ...
C. del Músic Barbieri, 7, izqu, 46018 ...
Based on product, the global cresols market is divided into para-cresol, meta-cresol, and ortho-cresol. Para-cresol will ... Global Cresols Market: Snapshot. The global cresols market is single-handedly driven by the burgeoning demand for vitamin E. ... and disposal of cresols is hampering the growth of the market. The Environmental Protection Agency (EPA) has listed cresols as ... the increasing usage of cresols for wider automotive applications is likely to shape the growth of the global cresols market. ...
2020 Prestige Laboratory Services (Pty) Ltd. All Rights Reserved. Designed & Developed By: Brandfire Digital ...
Our import data covers Mexican importers and buyers name and address, cresol import quantity and value, foreign country and ... Search for list of cresol importers in Mexico. ... List of Cresol Importerss in mexico. * Sin Razon Social Sin ... Cresol Importers in Mexico , Mexican Importers Directory of Cresol. Search for list of cresol importers in Mexico. Our import ... "LOWINOX TBM6, 6,6-DI-TERT-BUTIL-4,4-THIODI-M-CRESOL" ... BIOCIDAL PREPARATION BASED ON 4-CHLORINE M-CRESOL AND O- ...
An EXACT weight (2 digit after mg) is given free on the Certificate of Analyses
p-cresol metabolic process (GO:1901784) is_a cresol metabolic process m-cresol metabolic process (GO:0018925) is_a cresol ... Children of cresol metabolic process (GO:0042212) subject. relation. object. cresol catabolic process (GO:0046199) is_a cresol ... Parents of cresol metabolic process (GO:0042212) subject. relation. object. cresol metabolic process is_a toluene-containing ... Link to all annotated objects annotated to cresol metabolic process. Link to all direct and indirect annotations to cresol ...
6-Di-tert-butyl-p-cresol is an organic compound used as an antioxidant and preservative in food, fuel, and rubber products. It ...
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.. ...
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.. ...
Biomonitoring showed that in case of routine handling of cresols with required protection devices cresol concentrations were in ... cresol concentrations were in all cases below the limiting value of 200 mg cresols / l urine (Leng 2012).. Monitoring results ... As these results are in consistency it is concluded that the standard of RMMs and OCs in German industry using cresols is ... Each site handles produces or processes several thousand tonnes cresols per year. Data from about 100 workers per year over a ...
Meta-cresol is soluble in water 23.5 g/L at 20$^o$C, 58g/L at 100$^o$C. Even tho it is liquid at room temperature, it is not ... Meta-cresol is liquid, mp = 11$^o$C. It is difficult to turn these facts into an explanation, but there is something ... The pKa of meta-cresol suggests that it is slightly less acidic than phenol. As commented, the difference is quite subtle. You ... Imagine that room temperature is about 42$^o$C (a bit warm). Phenol is liquid, miscible with water; meta-cresol is liquid, not ...
Human p-cresol ELISA Kit Human p-cresol ELISA Kit. To Order Contact us: [email protected] ...
Trader and wholesaler of Cresol Red Sodium Salt offered by ARNISH LABORATES PRIVATE LIMITED. at latest price from Mumbai, ... Bromo Cresol Purpule Free Acid. Price : 1 INR/Kilograms. Minimum Order Quantity : 25. Send Inquiry ... Moreover, we offer this CRESOL RED SODIUM SALT in different packaging options as per the needs of clients at nominal rates. ... We are an unparalleled name engaged in offering premium quality CRESOL RED SODIUM SALT . Under most favorable conditions, it is ...
  • The name "cresol" is an adduct of phenol and their traditional source, creosote. (wikipedia.org)
  • In its chemical structure, a molecule of cresol has a methyl group substituted onto the ring of phenol. (wikipedia.org)
  • In this study, a novel spectrofluorometric assay based on $p$-cresol (4-methyl phenol) probe is developed for the measurement of HOBr scavenging activity. (tubitak.gov.tr)
  • when I googled the answer, i found out that m-cresol has a PKa value of 10.1 whereas phenol has 10.0. (stackexchange.com)
  • The pK a of meta-cresol suggests that it is slightly less acidic than phenol. (stackexchange.com)
  • Or, to phrase the question differently, is there some difference between phenol and meta-cresol that might explain, or contribute to the slight difference in pK a ? (stackexchange.com)
  • Except for that extra lattice energy that makes it a solid, phenol solubility in water would appear dramatically different from meta-cresol. (stackexchange.com)
  • In this study, health risks of occupational exposure to eight hazardous VOCs ( phenol , p-cresol, o/m-cresol, benzene, toluene, ethylbenzene, o-xylene, and m/pxylene) that are most likely to be emitted from swine buildings were assessed using Monte Carlo simulation. (cdc.gov)
  • Another isomer of cresol is called Benzyl alcohol, or alpha-cresol (α-cresol). (wikipedia.org)
  • Cresols have an odor characteristic to that of other simple phenols, reminiscent to some of a "coal tar" smell. (wikipedia.org)
  • Chemical burns result from exposure to strong acids, strong alkalis, phenols, cresols, mustard gas or phosphorus, with deaths from acid and alkali burns being most common. (medscape.com)
  • ortho -cresol ( o -cresol), meta -cresol ( m -cresol, and para -cresol ( p -cresol). (cdc.gov)
  • There are three forms (isomers) of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol). (wikipedia.org)
  • Based on product, the global cresols market is divided into para-cresol, meta-cresol, and ortho-cresol. (tmrblog.com)
  • Cresols (also known as hydroxytoluene, toluenol, benzol or cresylic acid) are a group of aromatic organic compounds. (wikipedia.org)
  • A novel hypobromous acid scavenging activity assay using $p$-cresol as" by BURCU BEKDEŞER, GÜLÜZAR ZEYTÜNLÜ et al. (tubitak.gov.tr)
  • Drinking contaminated water near garbage dumps or hazardous waste sites where cresols may be stored or buried. (cdc.gov)
  • hazardous waste sites where cresols may be stored or buried. (cdc.gov)
  • The Environmental Protection Agency (EPA) has listed cresols as hazardous air pollutant and they are, therefore, subjected to challenging regulatory pressures. (tmrblog.com)
  • Cresols may be formed normally in the body from other compounds. (cdc.gov)
  • Cresols may be formed normally in the body from other cresols you may be exposed by breathing air or by compounds. (cdc.gov)
  • A large portion of cresols produced worldwide is used for the manufacturing of organic intermediates such as herbicides (dinitro cresols, MCPA, and MCPP), phenolic and epoxy resins and plasticizers (phosphate esters), deodorizing and odor-enhancing compounds, and pharmaceuticals. (tmrblog.com)
  • While α -pinene and m -cresol SOA was found to be mainly composed of water-soluble compounds, 50-68 % of nocturnal SOA and 22-39 % of daytime limonene SOA are water-insoluble. (copernicus.org)
  • Biomonitoring showed that in case of routine handling of cresols with required protection devices but no respiratory protection devices, cresol concentrations were in all cases below the limiting value of 200 mg cresols / l urine (Leng 2012). (europa.eu)
  • But, concentrations of p-cresol and benzene exceeded their preliminary remediation goals (PRGs). (cdc.gov)
  • Exposure to cresols occurs mainly from breathing air containing car exhaust, air from homes heated with coal or wood, and smoking cigarettes. (cdc.gov)
  • Short-term and long-term studies with animals have shown similar effects from exposure to cresols. (wikipedia.org)
  • Occupational medical surveillance with data collected in the same period (1997- 2011) in the 2 manufacturing plants did not reveal any health effects like irritations of the skin, mucosa membranes or upper respiratory tract which could be derived to be from a possible cresol exposure at workplace. (europa.eu)
  • Exposure levels have been measured in the period from 1997 to 2011 related to all relevant activities of the workers where exposure to cresols was likely. (europa.eu)
  • Cancer risks of ethylbenzene, benzene and p-cresol were higher than EPA's benchmark of one per million. (cdc.gov)
  • Studies in animals have also found lesions inside the nose and thyroid gland damage in animals eating food containing mostly p -cresol or a mixture of m - and p -cresol. (cdc.gov)
  • These forms occur separately or as a mixture, which can also be called cresol or more specifically, tricresol. (wikipedia.org)
  • The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. (planteome.org)
  • Anisole converts to cresols under these conditions. (wikipedia.org)
  • Cresols are used to dissolve other chemicals, as disinfectants and deodorizers, and to make other chemicals. (cdc.gov)
  • For cresol bactericides or disinfectants the mechanism of action is due to the destruction of bacterial cell membranes. (wikipedia.org)
  • Household cleaners and disinfectants containing the skin and damage the kidneys, liver, blood, lungs, and cresols should be stored out of the reach of young brain. (cdc.gov)
  • citation needed] About half of the world's supply of cresols are extracted from coal tar. (wikipedia.org)
  • Cresols are a widely occurring natural and manufactured group of chemicals. (cdc.gov)
  • In air, cresols quickly break down into other chemicals. (cdc.gov)
  • Animal studies show that cresols may increase the ability of some carcinogenic chemicals to cause tumors. (cdc.gov)
  • Most recently, cresols have been used to create a breakthrough in manufacturing carbon nanotubes at scale that are separated and not twisted, without additional chemicals that change the surface properties of the nanotubes. (wikipedia.org)
  • Most of the cresols that you may ingest will enter the · In air, cresols quickly break down into blood stream, but less will enter the blood if there is other chemicals. (cdc.gov)
  • We offer the Para Chloro Meta Cresol (PCMC) also known as PCMC which is used as a preservative for drugs, paints, leather and adhesive chemicals. (shivshaktiindia.co.in)
  • o -Cresol, m -cresol, p -cresol, and mixed cresols have been found in at least 210, 22, 310, and 70 of the 1,678 current or former National Priority List sites, respectively, identified by the Environmental Protection Agency (EPA). (cdc.gov)
  • The opportunity in the global cresols market was worth US$266.07 mn in 2016 and is poised to reach US$325.01 mn by the end of 2023, progressing at a CAGR of 3.3% therein. (tmrblog.com)
  • Para-cresol will continue to be the leading revenue contributor until the end of 2023. (tmrblog.com)
  • Buy Cresol Red Indicator Solution Online In India At Best Price. (ibuychemikals.com)
  • Are You Wondering Where To Buy Cresol Red Indicator Solution Online In India? (ibuychemikals.com)
  • You Can Be Sure Of Getting The Best Cresol Red Indicator Solution Price In India. (ibuychemikals.com)
  • Cresols commonly occur as either solids or liquids because their melting points are generally close to room temperature. (wikipedia.org)
  • In soil, half the total amount of cresols will break solids and may be liquids if they are mixtures. (cdc.gov)
  • Lysol" has been used as a generic trademark to refer to such a cresol soap solution and remains used as such in some professional settings. (wikipedia.org)
  • Tests are available that measure the amount of cresols in Animal studies suggest that cresols probably would not the urine. (cdc.gov)
  • Biomonitoring results in urine confirmed that workers were exposed to cresols. (europa.eu)
  • We are named among the renowned Manufacturers, Suppliers and Exporters of Para Chloro Meta Cresol. (shivshaktiindia.co.in)
  • Cresols are found in many foods and in wood and tobacco smoke, crude oil, coal tar, and in chemical mixtures used as wood preservatives. (cdc.gov)
  • Cresols smell like medicine. (cdc.gov)
  • Most exposures to cresols are at very low levels that are not harmful, but cresols breathed, ingested, or applied to the skin at very high levels, can be very harmful because they are corrosive substances. (cdc.gov)
  • No human or animal studies have shown harmful effects from cresols on reproduction. (wikipedia.org)
  • Some of the key players in the global cresols market are Sasol Phenolics, Lanxess Aktiengesellschaft, SABIC Innovative Plastics, Atul Ltd, and Henan Hongye Technological Chemical Co. Ltd. (tmrblog.com)
  • How likely are cresols to cause cancer? (cdc.gov)
  • Our import data covers Mexican importers and buyers name and address, cresol import quantity and value, foreign country and other shipment details. (mexicoimporter.com)
  • Cresols are found in many foods and in wood skin contact. (cdc.gov)
  • Surprisingly, unexpectedly high SOA yields were found for m -cresol oxidation with OH radicals (3-9 %), with the highest yield under elevated RH (9 %), which is most likely attributable to a higher fraction of 3-methyl-6-nitro-catechol (MNC). (copernicus.org)
  • No human studies are available on the carcinogenic effects of cresols. (cdc.gov)
  • In soil, half the total amount of cresols will break down in about a week. (cdc.gov)
  • Cresols are corrosive and high levels can cause skin burns and internal burns if ingested, in addition to liver and kidney damage, and possibly death. (cdc.gov)
  • Inhalation of high levels of cresols for a short time results in irritation of the eyes, nose, and throat. (cdc.gov)
  • Skin contact with high levels of cresols can burn the skin and damage the kidneys, liver, blood, lungs, and brain. (cdc.gov)
  • Ingestion of high levels results in mouth and throat burns, abdominal pain, vomiting, · Avoiding environmental tobacco smoke, which kidney problems, and effects on the blood and nervous contains cresols, will reduce exposures to cresols. (cdc.gov)
  • Each site produces or processes several thousand tonnes cresols per year. (europa.eu)
  • As these results are in consistency it is concluded that the standard of RMMs and OCs in German industry using cresols is similar to the conditions at the chemical`s manufacturing site. (europa.eu)
  • The global cresols market is single-handedly driven by the burgeoning demand for vitamin E. Vitamin E is primarily used for fortification of food and beverages and in dietary supplements. (tmrblog.com)
  • Moreover, stringent environmental regulations pertaining to the production, packaging, transportation, usage, and disposal of cresols is hampering the growth of the market. (tmrblog.com)
  • To obtain all-inclusive information on forecast analysis of Cresols Market, request a PDF brochure here. (tmrblog.com)
  • However, meta-cresol is expected to exhibit a higher CAGR of 3.6% during the forecast period. (tmrblog.com)
  • If you do the same for meta-cresol, you get 10.09, 10.1 and 10.13. (stackexchange.com)
  • Meta-cresol is liquid, mp = 11 $^o$ C. It is difficult to turn these facts into an explanation, but there is something interesting about the solubilities. (stackexchange.com)
  • Providing you the best range of para chloro meta cresol (chloro cresol ) and para cholro meta cresol with effective & timely delivery. (shivshaktiindia.co.in)
  • We have the capability to deliver retail as well as bulk orders for Para Chloro Meta Cresol within the stipulated time frame. (shivshaktiindia.co.in)
  • What happens to cresols when they enter the environment? (cdc.gov)
  • Most of the cresols that you may ingest will enter the blood stream, but less will enter the blood if there is contact with the skin. (cdc.gov)
  • Small organisms in soil and water produce cresols when they break down materials in the environment. (cdc.gov)
  • Small organisms butter, and bacon, or drinking beverages such as in soil and water produce cresols when they break down coffee, black tea, whiskey, brandy, and rum, but materials in the environment. (cdc.gov)
  • This fact sheet answers the most frequently asked health questions (FAQs) about cresols. (cdc.gov)
  • How can cresols affect my health? (cdc.gov)
  • Cresols : health and safety guide. (who.int)
  • The present study aims to investigate α -pinene, limonene, and m -cresol with regards to their SOA formation potential dependent on relative humidity (RH) under night- (NO 3 radicals) and daytime conditions (OH radicals) and the resulting chemical composition. (copernicus.org)
  • Animal studies suggest that cresols probably would not affect reproduction in humans. (cdc.gov)