OrganismsDiseasesChemicals and Drugs
Coxsackievirus InfectionsEnterovirus B, HumanEnterovirusMyocarditisCoxsackie and Adenovirus Receptor-Like Membrane ProteinEnterovirus InfectionsHand, Foot and Mouth Disease
Coxsackievirus Infections
A heterogeneous group of infections produced by coxsackieviruses, including HERPANGINA, aseptic meningitis (MENINGITIS, ASEPTIC), a common-cold-like syndrome, a non-paralytic poliomyelitis-like syndrome, epidemic pleurodynia (PLEURODYNIA, EPIDEMIC) and a serious MYOCARDITIS.
Enterovirus B, Human
A species of ENTEROVIRUS infecting humans and containing 36 serotypes. It is comprised of all the echoviruses and a few coxsackieviruses, including all of those previously named coxsackievirus B.
Enterovirus
A genus of the family PICORNAVIRIDAE whose members preferentially inhabit the intestinal tract of a variety of hosts. The genus contains many species. Newly described members of human enteroviruses are assigned continuous numbers with the species designated "human enterovirus".
Myocarditis
Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
Coxsackie and Adenovirus Receptor-Like Membrane Protein
An Ig superfamily transmembrane protein that localizes to junctional complexes that occur between ENDOTHELIAL CELLS and EPTHELIAL CELLS. The protein may play a role in cell-cell adhesion and is the primary site for the attachment of ADENOVIRUSES during infection.
Enterovirus Infections
Hand, Foot and Mouth Disease
A mild, highly infectious viral disease of children, characterized by vesicular lesions in the mouth and on the hands and feet. It is caused by coxsackieviruses A.

T cells contribute to disease severity during coxsackievirus B4 infection. (1/525)

By using a model of coxsackievirus B4-induced disease, the question of whether tissue damage is due to the virus or to immune-mediated mechanisms was addressed. Both viral replication and T-cell function were implicated in contributing to the severity of disease. Three stages (I to III) of disease, which correspond to periods of high viral titers, low viral titers, and no infectious virus, have been identified. Stage I disease is considered to be primarily the result of viral replication. Immunopathological mechanisms appear to contribute to the severity of stage II and III disease. To investigate the role of T cells in contributing to the severity of disease, viral infection in CD8 knockout (ko) mice and CD4 ko mice was analyzed. CD8 T-cell responses appear to be beneficial during early, viral disease but detrimental in later disease when viral titers are diminishing. CD4 ko mice, unlike the parental strain, survived infection. Viral replication was lower in the CD4 ko mice. Was survival due to decreased viral replication or to the lack of T-helper-cell function? To investigate further the role of T helper cells in contributing to tissue damage, viral infection in two additional ko strains (interleukin-4 [IL-4] ko and gamma interferon ko strains) was examined. A clear correlation between viral replication and the outcome of infection was not observed. The absence of IL-4, which may influence T-helper-cell subset development, was advantageous during early viral disease but deleterious in later disease. The results suggest that T-cell-mediated immunity is both beneficial and detrimental during coxsackievirus B4 infection.  (+info)

Viral myocarditis: identification of five differentially expressed genes in coxsackievirus B3-infected mouse heart. (2/525)

Differences in host susceptibility to viral myocarditis caused by a given strain of coxsackievirus B3 (CVB3) are known to be largely related to host genetic factors. Little is known, however, about the key genes that encode determinants (mediators) of myocarditis development or the nature of injury. To identify these genes and further understand the molecular mechanisms of the disease process, we have used a murine model and the differential display technique to fingerprint mRNAs from CVB3-infected mouse hearts. Total RNA was extracted from hearts of 4- and 10-week-old A/J(H-2(a)) mice at day 4 after CVB3 infection, and mRNAs were detected by reverse transcriptase-polymerase chain reaction and subsequently analyzed on polyacrylamide DNA sequencing gels. The differentially displayed bands were confirmed by Northern hybridization using the bands as cDNA probes. Twenty-eight upregulated or downregulated bands were selected from the sequencing gels; among these, 2 upregulated and 3 downregulated cDNA fragments were confirmed by Northern hybridization. DNA sequence analysis and GenBank searching have determined that 4 of the 5 candidate genes are homologous to genes encoding Mus musculus inducible GTPase, mouse mitochondrial hydrophobic peptide (a subunit of NADH dehydrogenase), mouse beta-globin, and Homo sapiens cAMP-regulated response element binding protein (CREB) binding protein (CBP), respectively. The remaining candidate gene matches an unpublished cDNA clone, M musculus Nip21 mRNA (GenBank accession number, AF035207), which is homologous to human Nip2, a Bcl-2 binding protein. Our data suggest preliminarily that both structural and nonstructural genes are involved in myocarditis development. For the structural gene, beta-globin, we further confirmed its downregulation at the protein level by measuring the mean cell volume of red blood cells and found it was marginally reduced in the CVB3-infected group (P<0.06), with no change in hemoglobin concentration. Cardiac myoglobin concentration was also measured and found to be decreased (P<0.005), with a parallel decrease in total soluble protein in the CVB3-infected mouse myocardium (P<0.01). We also noted that the ratio of myoglobin to total protein was not significantly changed; this may be due to the downregulation of additional genes in the host heart, a number being observed on the differential display gels. The significant downregulation of beta-globin major gene expression in the heart may be relevant to impaired cardiac function in both the early and late postinfection period. The other identified nonstructural genes are known to be involved in regulation of gene expression, signal transduction pathways, and apoptotic cell death. The altered expression of structural and nonstructural genes may play important roles in the mediation of myocarditis development and perhaps other pathological processes in the heart.  (+info)

Hormonal regulation of CD4(+) T-cell responses in coxsackievirus B3-induced myocarditis in mice. (3/525)

Coxsackievirus B3 infection causes significant cardiac inflammation in male, but not female, B1.Tg.Ealpha mice. This gender difference in disease susceptibility correlates with selective induction of CD4(+) Th1 (gamma interferon-positive) cell responses in animals with testosterone, whereas estradiol promotes preferential CD4(+) Th2 (interleukin-4 positive [IL-4(+)]) cell responses. Differences in immune deviation of CD4(+) T cells cannot be explained by variation in B7-1 or B7-2 expression. Infection significantly upregulated both molecules, but no differences were detected between estradiol- and testosterone-treated groups. Significantly increased numbers of activated (CD69(+)) T cells expressing the gammadelta T-cell receptor were found in male and testosterone-treated male and female mice. In vivo depletion of gammadelta+ cells by using monoclonal antibodies inhibited myocarditis and resulted in a shift from a Th1 to Th2 response phenotype. Taken together, our results indicate that testosterone promotes a CD4(+) Th1 cell response and myocarditis by promoting increased gammadelta+ cell activation.  (+info)

gamma delta+ T cells regulate major histocompatibility complex class II(IA and IE)-dependent susceptibility to coxsackievirus B3-induced autoimmune myocarditis. (4/525)

Coxsackievirus B3 (CVB3) infection induces myocardial inflammation and myocyte necrosis in some, but not all, strains of mice. C57BL/6 mice, which inherently lack major histocompatibility complex (MHC) class II IE antigen, develop minimal cardiac lesions despite high levels of virus in the heart. The present experiments evaluate the relative roles of class II IA and IE expression on myocarditis susceptibility in four transgenic C57BL/6 mouse strains differing in MHC class II antigen expression. Animals lacking MHC class II IE antigen (C57BL/6 [IA+ IE-] and ABo [IA- IE-]) developed minimal cardiac lesions subsequent to infection despite high concentrations of virus in the heart. In contrast, strains expressing IE (ABo Ealpha [IA- IE+] and Bl.Tg.Ealpha [IA+ IE+]) had substantial cardiac injury. Myocarditis susceptibility correlated to a Th1 (gamma interferon-positive) cell response in the spleen, while disease resistance correlated to a preferential Th2 (interleukin-4-positive) phenotype. Vgamma/Vdelta analysis indicates that distinct subpopulations of gamma delta+ T cells are activated after CVB3 infection of C57BL/6 and Bl.Tg.Ealpha mice. Depletion of gamma delta+ T cells abrogated myocarditis susceptibility in IE+ animals and resulted in a Th1-->Th2 phenotype shift. These studies indicate that the MHC class II antigen haplotype controls myocarditis susceptibility, that this control is most likely mediated through the type of gamma delta T cells activated during CVB3 infection, and finally that different subpopulations of gamma delta+ T cells may either promote or inhibit Th1 cell responses.  (+info)

Activity of pleconaril against enteroviruses. (5/525)

The activity of pleconaril in cell culture against prototypic enterovirus strains and 215 clinical isolates of the most commonly isolated enterovirus serotypes was examined. The latter viruses were isolated by the Centers for Disease Control and Prevention during the 1970s and 1980s from clinically ill subjects. Pleconaril at a concentration of +info)

Susceptibility to myocarditis is dependent on the response of alphabeta T lymphocytes to coxsackieviral infection. (6/525)

Viral myocarditis is an important cause of heart failure and dilated cardiomyopathy. T lymphocytes are implicated in myocardial damage in murine models of coxsackievirus B3 (CVB3) myocarditis. We used knockout mice lacking CD4 (CD4(-/-)), CD8 (CD8(-/-)), both coreceptors (CD4(-/-)CD8(-/-)), or the T-cell receptor beta chain (TCRbeta(-/-)) to address the contribution of T-cell subpopulations to host susceptibility to CVB3 myocarditis. Severity of disease was magnified in CD8(-/-) mice but attenuated in CD4(-/-) mice, consistent with a pathogenic role for CD4(+) lymphocytes. Elimination of both CD4 and CD8 molecules from T lymphocytes by genetic knockout better protected mice from myocarditis, demonstrating that both CD4(+) and CD8(+) T cells contribute to host susceptibility. The same benefit occurred in TCRbeta(-/-) mice, with prolonged survival and minimal myocardial disease observed after CVB3 infection. Elevated interferon-gamma and decreased tumor necrosis factor-alpha expression are associated with attenuated myocardial damage in CD4(-/-)CD8(-/-) mice. These results show that the presence of TCRalphabeta(+) T cells enhances host susceptibility to myocarditis. The severity of myocardial damage and associated mortality are dependent on the predominant T-cell type available to respond to CVB3 infection. One mechanism by which CD4(+) and CD8(+) T-cell subsets influence the pathogenesis of myocarditis may involve specific cytokine expression patterns.  (+info)

Coxsackievirus B4 myocarditis in an orangutan. (7/525)

A 37-year-old female orangutan died at the zoological garden. Autopsy examination demonstrated severe coxsackievirus B4 myocarditis immunohistochemically as a cause of the death. Apoptosis of the cardiac muscle cells was observed using the TdT-mediated dUTP-biotin nick endo labeling method and was considered to play a role in the myocarditis. Congestion of the liver and both lungs due to cardiac failure was also observed. Coxsackievirus infection is found frequently in the Okinawan human population. The present orangutan's infection might have come from visitors who were allowed to go near the orangutan. Malignant tumors, severe suppurative infections, and intestinal parasite infections were not observed. Epstein-Barr virus DNA was detected in lymph nodes, but there was no Burkitt's lymphoma.  (+info)

The role of B lymphocytes in coxsackievirus B3 infection. (8/525)

Coxsackieviruses are important human pathogens, frequently causing myocarditis, pancreatitis, and a variety of less severe diseases. B lymphocytes appear central to the interaction between these viruses and their mammalian hosts, because agammaglobulinemic humans, genetically incapable of antibody production, are susceptible to chronic infections by coxsackieviruses and related enteroviruses, such as poliovirus and echovirus. However, recent studies show that Type B coxsackievirus (CVB) infects B lymphocytes soon after infection, suggesting the possibility that these cells may play some role in virus dissemination and/or that the virus may be able to modulate the host immune response. We analyzed the role of B lymphocytes in CVB infection and confirmed that CVB infects B lymphocytes, and extended these findings to show that this is a productive infection involving approximately 1 to 10% of the cells; however, infectious center assays show that other splenocytes are infected at approximately the same frequency. Virus is readily detectable by in situ hybridization in the spleen of immunocompetent mice but is difficult to detect in mice deficient in B cells (BcKO mice), consistent with much of the splenic signal being the result of B cell infection. Surprisingly, given the extent of their infection, B cells express barely detectable levels of the murine coxsackievirus-adenovirus receptor (mCAR), suggesting that another means of cell entry may be used. We found no evidence of B cell depletion following CVB infection, indicating that this is not the explanation for the transient immunosuppression previously reported. Virus replication and dissemination are slightly delayed in BcKO mice, consistent with B cells' playing a role as an important early target of infection and/or a means to distribute the virus to many tissues. In addition, we show that BcKO mice recapitulate a central feature of human agammaglobulinemia: CVB establishes chronic infection in a variety of organs (heart, liver, brain, kidney, lung, pancreas, spleen). In most of these tissues the viral titers remain high (10(5)-10(8) plaque forming units (pfu) per gram of tissue) for the life of the mouse, and in several there is severe pathology, particularly severe myocardial fibrosis with ventricular dilation, reminiscent of the dilated cardiomyopathy seen in humans with chronic enteroviral myocarditis. Transfer of B and/or T cells from non-immune mice had no discernible effect, whereas equivalent transfers from immune mice often resulted in transient or permanent disappearance of detectable CVB.  (+info)

Coxsackievirus Infections
There is no vaccine to prevent coxsackievirus infection. Hand washing is the best protection. Remind everyone in your family to wash their hands frequently, particularly after using the toilet (especially those in public places), after changing a diaper, before meals, and before preparing food. Shared toys in childcare centers should be routinely cleaned with a disinfectant because the virus can live on these objects for days.. Kids who are sick with a coxsackievirus infection should be kept out of school or childcare for a few days to avoid spreading the infection.. The duration of an infection varies widely. For fever without other symptoms, a childs temperature may return to normal within 24 hours, although the average fever lasts 3 to 4 days. Hand, foot, and mouth disease usually lasts for 2 or 3 days; viral meningitis can take 3 to 7 days to clear up.. ...
https://www.rchsd.org/health-articles/coxsackievirus-infections/
Coxsackievirus Infection (Symptoms, signs, causes, treatments & definition) - Medigest
Looking for information on Coxsackievirus Infection? Medigest has all you need to know about Coxsackievirus Infection - Symptoms and Signs, Causes, Treatments and definition
https://www.medigest.uk/diseases/coxsackievirus-infection/
Coxsackievirus Infection: Causes, Symptoms, Risk Factors, Treatments And Prevention - Boldsky.comCoxsackievirus Infection: Causes, Symptoms, Risk Factors, Treatments And Prevention - Boldsky.com
Coxsackievirus is a virus type that belongs to the genus. It causes coxsackievirus infection (CI) which is highly contagious and spreads from individual to individual through direct contact by contaminated hands, saliva, respiratory droplets and faeces.
https://www.boldsky.com/health/disorders-cure/coxsackievirus-infection-causes-symptoms-risks-treatment-prevention-134074.html
Coxsackievirus InfectionsCoxsackievirus Infections
Coxsackievirus infections can spread from person to person. In most cases, the viruses cause mild flu-like symptoms, but can lead to more serious infections.
http://kidshealth.org/RadyChildrens/en/parents/coxsackie.html?view=rr
Coxsackievirus InfectionsCoxsackievirus Infections
Coxsackievirus infections can spread from person to person. In most cases, the viruses cause mild flu-like symptoms, but can lead to more serious infections.
http://kidshealth.org/BarbaraBushChildrens/en/parents/coxsackie.html
T-cell Receptor Vbeta8.1 Peptide Reduces Coxsackievirus-induced Cardiopathology During Murine Acquired Immunodeficiency...
Infection of people with human immunodeficiency virus (HIV) as well as LP- BM5 infection in mice results in progressive deterioration of the immune system in the majority of untreated hosts. Peptide immunotherapy has been shown to be effective in the stimulation or immunoregulation of T-helper 1 (TH1) and T-helper 2 (TH2) response subsets. In murine acquired immunodeficiency syndrome (AIDS), TH1 deficiency enables the host to be susceptible to coxsackievirus infection, inducing cardiopathology in a short period. T-cell receptor (TCR) V 8.1 peptide, a 16-mer peptide containing the entire CFR1 segment and part of the FR2 region of human V 8, showed both an immunoregulating and immunostimulating effect in murine AIDS. TCR V 8.1 peptide acts on T cells promoting interleukin-2 production and therefore enhancing a cellmediated immune response. It retarded development of cardiopathology due to coxsackievirus infection. Retrovirus infected mice treated with the peptide showed a longer life span than the ...
http://www.openthesis.org/documents/T-cell-Receptor-Vbeta81-Peptide-17313.html
Coxsackievirus Infections - Kids Health | Herpes Advice
foot and mouth disease: current situation and perspective of India N Sarma FMD is usually caused by Coxsackie A16 and is characterized by four 8 mm ulcers on the tongue, buccal mucosa and occasionally tonsils columns. Accessed Nov. In defense of empirical acyclovir therapy in some newborns. It may be possible for patients with nonclassic CAH to stop medication as adults if their symptoms go away. Mothers also benefit from this closeness. Low birth weight is associated with neonatal infection. Always follow your healthcare professionals instructions.. Herpes simplex and herpes zoster viruses. Acquired hydrocephalus develops at the time of birth or at some point afterward. We will respect your doctors right to privacy. The EarWell System was so successful, in January 2010 Becon Medical began making the molds available to pediatricians across the country. The ring is then covered over by the foreskin. Red eyes or an earache are also common symptoms of flu in newborns. Phylogenetic analyses of the ...
http://www.wdmac.com/coxsackievirus-infections-kids-health/
Heart-reactive autoantibodies in mice following coxsackievirus B3 (CB3) myocarditis<...
TY - JOUR. T1 - Heart-reactive autoantibodies in mice following coxsackievirus B3 (CB3) myocarditis. AU - Wolfgram, L. J.. AU - Herskowitz, A.. AU - Beisel, K. W.. AU - Rose, N. R.. PY - 1984/1/1. Y1 - 1984/1/1. UR - http://www.scopus.com/inward/record.url?scp=0021167263&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0021167263&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0021167263. VL - 43. SP - no. 2448. JO - Federation Proceedings. JF - Federation Proceedings. SN - 0014-9446. IS - 6. ER - ...
https://creighton.pure.elsevier.com/en/publications/heart-reactive-autoantibodies-in-mice-following-coxsackievirus-b3
Primary neurons become less susceptible to coxsackievirus B5 following maturation: The correlation with the decreased level of...
TY - JOUR. T1 - Primary neurons become less susceptible to coxsackievirus B5 following maturation. T2 - The correlation with the decreased level of CAR expression on cell surface. AU - Ahn, Jeonghyun. AU - Jee, Youngmee. AU - Seo, Ilseon. AU - Seung, Yong Yoon. AU - Kim, Dong Hou. AU - Yoo, Kyum Kim. AU - Lee, Heuiran. PY - 2008/3. Y1 - 2008/3. N2 - Coxsackievirus B (CVB) is one of the major pathogens of aseptic meningitis and meningioencephalitis, particularly in newborn infants. To analyze the influence of neural maturation on susceptibility to CVB infection, we prepared immature and mature neurons from 16-day-old BALB/c embryonic cortex. In contrast to immature neurons, mature neurons were less susceptible to CVB5 infection, as indicated by the decrease of cytopathic features. In mature neurons, progeny virus production was significantly hindered, and virus capsid protein VP1 synthesis and virus genome amplification were concomitantly reduced. In addition, the expression of coxsackievirus and ...
https://miami.pure.elsevier.com/en/publications/primary-neurons-become-less-susceptible-to-coxsackievirus-b5-foll
Coxsackievirus Incubation Period, Symptoms, Treatment & RashCoxsackievirus Incubation Period, Symptoms, Treatment & Rash
Coxsackievirus infection symptoms and signs include sore throat, rash, and blisters. Read about coxsackievirus types, infection causes, treatment, incubation period, diagnosis, contagious period, and risk factors.
https://www.rxlist.com/coxsackie_virus/article.htm
Molecular Biology Laboratory - Old-PublicationsMolecular Biology Laboratory - Old-Publications
PMID: 26941423. Anderson ME, Goldhaber J, Houser SR, Puceat M, Sussman MA Embryonic stem cell-derived cardiac myocytes are not ready for human trials. Circ Res 2014 Jul 18 115(3):335-8. Epub 2014 Jun 16. Din S, Konstandin MH, Johnson B, Emathinger J, Völkers M, Toko H, Collins B, Ormachea L, Samse K, Kubli DA, De La Torre A, Kraft AS, Gustafsson AB, Kelly DP, Sussman MA Metabolic dysfunction consistent with premature aging results from deletion of pim kinases. Circ Res 2014 Jul 18 115(3):376-87. Epub 2014 Jun 10. Sin J, Puccini JM, Huang C, Konstandin MH, Gilbert PE, Sussman MA, Gottlieb RA, Feuer R The impact of juvenile coxsackievirus infection on cardiac progenitor cells and postnatal heart development. PLoS Pathog 2014 Jul 10(7):e1004249. Epub 2014 Jul 31. Hariharan N, Sussman MA Pin1: A molecular orchestrator in the heart. Trends Cardiovasc Med 2014 Jun 4 Epub 2014 Jun 4. Hariharan N, Sussman MA Stressing on the nucleolus in cardiovascular disease. Biochim Biophys Acta 2014 Jun ...
https://heart.sdsu.edu/old-publications/
Beneficial effects of captopril in coxsackievirus myocarditis. | CirculationBeneficial effects of captopril in coxsackievirus myocarditis. | Circulation
Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. ...
http://circ.ahajournals.org/content/82/5/1882.1
10 Best Clinics for Coxsackievirus-Induced Cardiomyopathy Treatment in Heidelberg [2021 Prices]10 Best Clinics for Coxsackievirus-Induced Cardiomyopathy Treatment in Heidelberg [2021 Prices]
Coxsackievirus-Induced Cardiomyopathy Treatment clinics in Heidelberg at the best price. Find doctors, specialized in Cardiology and compare prices, costs and reviews.
https://www.mymeditravel.com/coxsackievirusinduced-cardiomyopathy-treatment-procedures-in-heidelberg-germany
Pyrrolidine Dithiocarbamate Reduces Coxsackievirus B3 Replication through Inhibition of the Ubiquitin-Proteasome Pathway |...Pyrrolidine Dithiocarbamate Reduces Coxsackievirus B3 Replication through Inhibition of the Ubiquitin-Proteasome Pathway |...
PDTC has been reported to possess strong antiviral activity against replication of influenza virus, rhinovirus, and poliovirus. However, the mechanism was not well elucidated (24, 58). In the current study, we have explored the manner in which PDTC inhibits both coxsackievirus B3 (CVB3) viral RNA synthesis and virus structural protein expression. We provide evidence that PDTC exerts its antiviral activity intracellularly, most likely independent of viral entry.. Divalent metal ions including copper and zinc have been reported to play an essential role in mediating various biological functions of PDTC (11, 13, 20, 30). Studies by Furuta et al. and Kim et al. suggest that PDTC may act as an ionophore, recruiting extracellular copper and zinc into the cells (23, 31). Treatment with PDTC resulted in an increase of intracellular zinc and redox reactive Cu2+, and depletion of extracellular copper and zinc prevented PDTC-induced cell death and inhibition of NF-κB activation. In the present study, we ...
https://jvi.asm.org/content/79/13/8014
The tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart diseaseThe tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart disease
Infections are thought to be important in the pathogenesis of many heart diseases. Coxsackievirus B3 (CVB3) has been linked to chronic dilated cardiomyopathy, a common cause of progressive heart disease, heart failure and sudden death. We show here that the sarcoma (Src) family kinase Lck (p56lck) i …
https://pubmed.ncbi.nlm.nih.gov/10742150/?dopt=Abstract
CoxsackievirusCoxsackievirus
Hand, foot, and mouth disease is an early childhood condition most commonly caused by the coxsackievirus. This viral infection is named after its classic symptoms: small ulcers on the inside cheeks, gums, and tongue, and a red rash that can result in blisters on the palms of the hands and soles of the feet.. Coxsackievirus is easily spread from an infected person through nasal secretions, saliva, droplets in the air after a cough or sneeze, fluid from open blisters, or stool contamination. The best protection against its spread is thorough hand washing, especially after diaper changes or use of the bathroom. Breakouts of the disease are common in child care settings, preschools, and elementary schools.. Symptoms begin to appear between 3 and 7 days following exposure. The initial symptoms include fever, loss of appetite, and sore throat, followed by small blisters in the mouth and a red skin rash commonly found on the palms and soles. Treatment is aimed at relieving symptoms with fever reducers ...
https://www.uspharmacist.com/article/coxsackievirus
2015-2019 Future Horizons and Growth Strategies in the Coxsackievirus Testing Market: Country Forecasts2015-2019 Future Horizons and Growth Strategies in the Coxsackievirus Testing Market: Country Forecasts
The report presents a detailed analysis of the Coxsackievirus diagnostics market in the US, Europe, (France, Germany, Italy, Spain, UK) and Japan. Current scientific ...
https://www.reportlinker.com/p03247080/Future-Horizons-and-Growth-Strategies-in-the-Coxsackievirus-Testing-Market-Country-Forecasts.html
For instance, cluster T2 which does not display a strongly conserved motif primarily based on its entropy plot only yields an...For instance, cluster T2 which does not display a strongly conserved motif primarily based on its entropy plot only yields an...
Cluster T3 is then matched to be perhaps phosphorylated by CDK group, CDK1, CDK2, MAPK group owing to a conserved proline in situation +one as shown in Figure three. Even more analyzing the matched motifs, a literature study is done in get to locate research that experimentally recognize human kinases which phosphorylate certain virus protein substrates. Prior scientific studies [33,34] display that CK2 group phosphorylates hepatitis C virus (HCV) NS5A proteins and HIV-1 gp120, gp41, p27, and p17 proteins to identify a few, on both S and T residues. These results assistance the matching of MDD teams S1 and T1 with CK2 group. CK2 household phosphorylates various proteins which are associated with the viral an infection of HCV, HIV, HSV, HBV and HPV [35,36]. With regard to PKB which is matched MK-2461 structurewith cluster S3, it is noted to be concerned in the regulation of the herpes simplex virus (HSV) one [37]. Experimental study also statements that PKB signaling rewards coxsackie virus B3 ...
https://cathepsin-s.com/2016/07/27/for-instance-cluster-t2-which-does-not-display-a-strongly-conserved-motif-primarily-based-on-its-entropy-plot-only-yields-an-precision-of-a-46-six-when-utilised-separately/
File list - microbewiki
Figure: Secondary structures of the Coxsackie Virus B RNA and the encoded proteins. Taken from van Ooij, M.J., Vogt, D.A., Paul, A., Castro, C., Kuijpers, J., van Kuppeveld, F.J., Cameron, C.E., Wimmer, E., Andino, R. and Melchers, W.J. 2006, with perm ...
https://microbewiki.kenyon.edu/index.php/Special:ListFiles/Bjardin
RCSB PDB - 1RFR: NMR structure of the 30mer stemloop-D of coxsackieviral RNARCSB PDB - 1RFR: NMR structure of the 30mer stemloop-D of coxsackieviral RNA
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
https://www.rcsb.org/structure/1RFR
3D View - 4K4X: Coxsackievirus B3 polymerase elongation complex (r2 form), rna 3D View Report Page3D View - 4K4X: Coxsackievirus B3 polymerase elongation complex (r2 form), rna 3D View Report Page
4K4X: Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
http://www.rcsb.org/pdb/explore/jmol.do?structureId=4K4X&residueNr=GOL
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This report is available at 20% Discount till 31 December 2017. To avail discount please contact at +1-888-391-5441 / [email protected] ...
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3cdw.1 | SWISS-MODEL Template Library
SWISS-MODEL Template Library (SMTL) entry for 3cdw.1. Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate
https://swissmodel.expasy.org/templates/3cdw
Antibodies to Coxsackie B viruses in congestive cardiomyopathy. | HeartAntibodies to Coxsackie B viruses in congestive cardiomyopathy. | Heart
Fifty patients with congestive cardiomyopathy have been studied for evidence of previous Coxsackie B virus infection and compared with age- and sex-matched controls who had been admitted to hospital for investigation of other cardiac diseases. High neutralisation titres (greater than or equal to 1024) to Coxsackie B viruses were more common among the controls. On subdividing the patients according to their length of symptomatic history before study, high titres were more common only in those with a short history (less than or equal to 1 year). High titres were more common when there had been a febrile illness at the onset of symptoms. Endomyocardial biopsies of 18 patients disclosed no evidence of myocarditis, or, in 12 cases, of viral involvement. Although the evidence remains circumstantial, these results support the theory that Coxsackie B viruses may cause congestive cardiomyopathy and encourage further research into the mechanisms of myocardial cell damage by these visuses. ...
http://heart.bmj.com/content/41/6/692
acute viral myocarditis是什么意思 海词词典acute viral myocarditis是什么意思 海词词典
海词词典，最权威的学习词典，专业出版acute viral myocarditis是什么意思，acute viral myocarditis的用法，acute viral myocarditis翻译和读音等详细讲解。海词词典：学习变容易，记忆很深刻。
http://m.dict.cn/acute%20viral%20myocarditis%0D
Coxsackievirus | definition of coxsackievirus by Medical dictionaryCoxsackievirus | definition of coxsackievirus by Medical dictionary
Looking for online definition of coxsackievirus in the Medical Dictionary? coxsackievirus explanation free. What is coxsackievirus? Meaning of coxsackievirus medical term. What does coxsackievirus mean?
https://medical-dictionary.thefreedictionary.com/coxsackievirus
What you need to know about Coxsackie virus: the seven most important facts - The International Massmedia AgencyWhat you need to know about Coxsackie virus: the seven most important facts - The International Massmedia Agency
How it spreads. The virus is contagious and spreads through direct contact with saliva, mucus and even fecal matter from infected people. Quite often there are small epidemics of this virus in kindergartens and schools. Skin rash usually disappears by itself after a week, and in most cases need no treatment except symptomatic like paracetamol against fever. There are no vaccines however, infected persons are most contagious during the first week, and the possibility of transmission of virus persists for another few weeks. Can you get Coxsackie virus more than once. Yes, infection only results in the emergence of immunity to one specific type, but the Coxsackie virus, as mentioned above, is divided into three types. How to protect yourself from infection. One of the main and most effective methods of prevention of infection with Coxsackie virus is the observance of strict rules of hygiene. First and foremost, you must frequently wash their hands with soap and water especially after touching ...
https://intmassmedia.com/2017/08/15/what-you-need-to-know-about-coxsackie-virus-the-seven-most-important-facts/
In vivo significance of T cells in the development of Coxsackievirus B3 myocarditis in mice. Immature but antigen-specific T...In vivo significance of T cells in the development of Coxsackievirus B3 myocarditis in mice. Immature but antigen-specific T...
Acute myocardial damage similar to that seen in human myocarditis occurs in BALB/c mice after infection with coxsackievirus B3 (CB3) or encephalomyocarditis virus (EMC). To investigate the role of antigen-specific T cells in the pathogenesis of this disorder, we compared CB3 disease expression in T cell-deficient, athymic nude (nu/nu) mice, in heterozygote (nu/+) mice with normal T cell function, and in nu/nu mice reconstituted with spleen cells from CB3- or EMC-infected nu/+ mice. Acute myocarditis occurred in both nu/nu and nu/+ mice. Severe myocarditis, however, developed only in nu/+ and nu/nu mice reconstituted with CB3-sensitized T cells, but not in those reconstituted with EMC-sensitized T cells. Myocardial virus titer and serum anti-CB3 antibody production were similar in nu/+ and nu/nu groups. Additionally, the presence of Thy 1.2 (pan T), Ly 1 (precursor of other T cell subsets), and Ly 2 (suppressor/cytotoxic T) positive cells was demonstrated in the myocardium in nu/+ and nu/nu mice ...
http://circres.ahajournals.org/content/67/3/589
Coxsackie B4 virus - WikipediaCoxsackie B4 virus - Wikipedia
Coxsackie B4 Virus are enteroviruses that belong to the Picornaviridae family. These viruses can be found worldwide. They are positive-sense, single-stranded, non-enveloped RNA viruses with icosahedral geometry. Coxsackieviruses have two groups, A and B, each associated with different diseases. Coxsackievirus group A is known for causing hand-foot-and-mouth diseases while Group B, which contains six serotypes, can cause a varying range of symptoms like gastrointestinal distress myocarditis. Coxsackievirus B4 has a cell tropism for natural killer cells and pancreatic islet cells. Infection can lead to beta-cell apoptosis which increases the risk of insulitis. Coxsackievirus B4 is one of the six serotypes found in Group B and is a positive sense, single-stranded, non-enveloped RNA virus. Its genome is linear and is 7,293 nucleotides in length with both a 5 and 3 untranslated region and encodes its own 3 poly-A tail. The 5 untranslated region contains an internal ribosomal entry site (Type I ...
https://en.wikipedia.org/wiki/Coxsackie_B4_virus
Expression of nitric oxide synthase in a murine model of viral myocarditis induced by coxsackievirus B3Expression of nitric oxide synthase in a murine model of viral myocarditis induced by coxsackievirus B3
Nitric oxide is known to participate in the immune and inflammatory processes. In this study, we investigated the production of nitric oxide (NO) in murine viral myocarditis induced by coxsackievirus B3. The expression of inducible NO synthase (iNOS) mRNA in the heart first appeared on day 4 after v …
https://pubmed.ncbi.nlm.nih.gov/8607880/
Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated...Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated...
Interest in CAR stems from its function as the primary high affinity receptor for Ad serotype 5, the most commonly used adenoviral vector in gene therapy protocols. CAR expression is the main determinant in gene transfer to normal tissue as ectopic expression of CAR in transgenic mice leads to several magnitudes of increase in adenovirus transducibility of tissues that are otherwise refractory to Ad-mediated gene expression [13-17]. As well, although decay accelerating factor (DAF, CD55) was the first described CVB receptor [18, 19], CAR is necessary and sufficient for CVB infection in vitro [20]. Thus, the expression levels of CAR may also govern the susceptibility to CVB diseases and the pathological consequences of CVB viral infection. In this context, acute viral myocarditis and myositis are inflammatory diseases affecting cardiac and skeletal muscle that can result from infection by the Coxsackie B virus. In both humans and rodents, heart is among the tissues showing the greatest abundance ...
https://bmccellbiol.biomedcentral.com/articles/10.1186/1471-2121-5-42
Generation of cytotoxic t lymphocytes during coxsackievirus b-3 infect by C Y. Wong, J J. Woodruff et al.Generation of cytotoxic t lymphocytes during coxsackievirus b-3 infect by C Y. Wong, J J. Woodruff et al.
Wong, C Y.; Woodruff, J J.; and Woodruff, J F., Generation of cytotoxic t lymphocytes during coxsackievirus b-3 infection. Iii. Role of sex. (1977). Subject Strain Bibliography 1977. 942 ...
https://mouseion.jax.org/ssbb1977/942/
Coxsackie Virus - Types, Causes, Symptoms, Treatment, Pictures, Transmission | Diseases PicturesCoxsackie Virus - Types, Causes, Symptoms, Treatment, Pictures, Transmission | Diseases Pictures
Coxsackie virus belongs to the family of Picornaviridae (Picornavirus) and enterovirus genus. They have small RNA virus in them and it was first invented at the
https://diseasespictures.com/coxsackie-virus-infection/
What is a Coxsackie Virus? (with pictures)What is a Coxsackie Virus? (with pictures)
A coxsackie virus is a virus in the Picornaviridae family, which can cause symptoms like nausea, diarrhea, cramps, rashes, and...
http://www.wisegeekhealth.com/what-is-a-coxsackie-virus.htm
CiNii 論文 - Detection of Transforming Growth Factor-β1 in Coxsackie B3 Virus-Induced Murine...
To clarify the role of TGF-β1 in myocardial healing process after virus-induced myocarditis, we have examined the time course of TGF-β1 expression and its localization in myocardial healing process after Coxsackie B3-induced murine myocarditis. TGF-β1 immunoreactivity increased in parallel with its mRNA level and reached a peak at 10 days after Coxsackie B3 virus inoculation. Immunohistochemically, TGF-β1 was localized at pre-necrotic area at an early phase (5 days); it increased and extended to the area around the necrotic foci when necrosis became manifest (10 days); it decreased when macrophages and fibroblasts migrated to the necrotic foci (15 days); and then it reached a normal level and localized a little in perivascular and calcified regions (30 days). To our knowledge, this is the first study which demonstrates that TGF-β1 mRNA increases in viral-induced myocarditis at acute inflammatory phase. This result suggests that TGF-β1 promotes the migration of macrophages and fibroblasts ...
https://ci.nii.ac.jp/naid/10008976310
Aging | The regulatory role of miR-107 in Coxsackie B3 virus replication - Figure
Coxsackie B3 virus (CVB3) is a member of small RNA viruses that belongs to the genus Enterovirus of the family Picornaviridae and CVB3 is the main pathogen of acute and chronic viral myocarditis. In this study RT-qPCR was used to determine the expression of miR-107 in CVB3-infected and uninfected HeLa cells. The experimental results show that the level of miR-107 began to rise at 4 h after the infection, and significantly boosted at 6 h. Based on the results of this experiment, we consider that miR-107 expression is related to CVB3 infection. In order to further clarify the effect of miR-107 in the process of CVB3 infection, we studied the effect of miR-107 upstream and downstream target genes on CVB3 replication. Levels of the target RNAs were detected by RT-qPCR after CVB3 infection, and the expression of CVB3 capsid protein VP1 by western blot analysis. Then the virus in the supernatant was quantitated via a viral plaque assay, reflecting the release of the virus. The experimental results showed that
https://www.aging-us.com/figure/103488/f5
Aging | The regulatory role of miR-107 in Coxsackie B3 virus replication - Full Text
Full Text - Coxsackie B3 virus (CVB3) is a member of small RNA viruses that belongs to the genus Enterovirus of the family Picornaviridae and CVB3 is the main pathogen of acute and chronic viral myocarditis. In this study RT-qPCR was used to determine the expression of miR-107 in CVB3-infected and uninfected HeLa cells. The experimental results show that the level of miR-107 began to rise at 4 h after the infection, and significantly boosted at 6 h. Based on the results of this experiment, we consider that miR-107 expression is related to CVB3 infection. In order to further clarify the effect of miR-107 in the process of CVB3 infection, we studied the effect of miR-107 upstream and downstream target genes on CVB3 replication. Levels of the target RNAs were detected by RT-qPCR after CVB3 infection, and the expression of CVB3 capsid protein VP1 by western blot analysis. Then the virus in the supernatant was quantitated via a viral plaque assay, reflecting the release of the virus. The experimental results
https://www.aging-us.com/article/103488/text
OPUS 4 | SearchOPUS 4 | Search
Dilated Cardiomyopathy is a chronic myocardial disease characterized by progressive depression of contractile function and ventricular dilatation. It is the leading cause of heart failure and the most common reason for heart transplantation. Besides genetic causes, viral infection and autoimmune response are considered to play a major role in the etiology of the disease. Among different viruses that cause the disease, Coxsackievirus B3 (CVB3) is predominantly associated with the development and progression of the disease. Moreover, Coxsackievirus induced myocarditis in the mouse mimics human myocarditis and dilated cardiomyopathy. In the murine model, the disease progresses over a period of 90 days from acute myocarditis to chronic myocarditis and further develops into dilated cardiomyopathy and congestive heart failure. Though much is known about the progression of the disease, the molecular events occurring after infection with CVB3 are not completely understood. In the current study, ...
https://epub.ub.uni-greifswald.de/solrsearch/index/search/searchtype/simple/query/%2A%3A%2A/browsing/true/rows/20/sortfield/author/sortorder/asc/facetNumber_institute/all/institutefq/Arbeitsgruppe+%22Funktionelle+Genomforschung%22
OPUS 4 | SearchOPUS 4 | Search
Dilated Cardiomyopathy is a chronic myocardial disease characterized by progressive depression of contractile function and ventricular dilatation. It is the leading cause of heart failure and the most common reason for heart transplantation. Besides genetic causes, viral infection and autoimmune response are considered to play a major role in the etiology of the disease. Among different viruses that cause the disease, Coxsackievirus B3 (CVB3) is predominantly associated with the development and progression of the disease. Moreover, Coxsackievirus induced myocarditis in the mouse mimics human myocarditis and dilated cardiomyopathy. In the murine model, the disease progresses over a period of 90 days from acute myocarditis to chronic myocarditis and further develops into dilated cardiomyopathy and congestive heart failure. Though much is known about the progression of the disease, the molecular events occurring after infection with CVB3 are not completely understood. In the current study, ...
https://epub.ub.uni-greifswald.de/solrsearch/index/search/searchtype/simple/query/%2A%3A%2A/browsing/true/rows/20/sortfield/title/sortorder/asc/facetNumber_institute/all/start/0/institutefq/Arbeitsgruppe+%22Funktionelle+Genomforschung%22/subjectfq/Proteomanalyse
Arterial Structure and Function Following Viral MyocarditisArterial Structure and Function Following Viral Myocarditis
Acute viral myocarditis is an uncommon inflammatory disease of the myocardium. Little is known about the long-term cardiovascular risk for individuals
https://findanexpert.unimelb.edu.au/scholarlywork/1347943-arterial-structure-and-function-following-viral-myocarditis
Chronic Illness Report 6Chronic Illness Report 6
Editorial comment: Cunningham and his associates determined whether enterovirus sequences were present in muscle biopsy specimens obtained from patients with PVFS. Two classes of probes were used: (i) so-called generic probes that were enterovirus group-specific; and (ii) probes that made it possible to determine whether virus RNA synthesis was asymmetrical (typical of cytic infection) or symmetrical (typical of defective viral RNA synthesis). Importantly, appropriate probes were used to test whether specimens also were positive for EBV sequences. Seventeen patients were studied that had fatigue for six or more months. Of these, five were mates and 13/17 were at midlife, i.e., 35-55 years of age. Then patients were tested for neutralizing antibody to Coxsackievirus B3; five were negative. Eleven patients were tested for IgM to Coxsackievirus B2, 3 and 5; of these, 10 were negative. Such results indicate that antibodies to Coxsackieviruses are not good surrogate markers for PVFS. When muscle ...
http://meactionuk.org.uk/Chronic_Illness_Report_6.htm
Interstitial and Coxsackievirus B Myocarditis in Infants and Children: A Comparative Histologic and Immunofluorescent Study of...Interstitial and Coxsackievirus B Myocarditis in Infants and Children: A Comparative Histologic and Immunofluorescent Study of...
Fifty hearts of infants and children were collected at routine autopsies and were surveyed by means of routine histologic techniques and immunofluorescent antib
https://jamanetwork.com/journals/jama/article-abstract/337190
Coxsackie virus | Royal Rife Frequencies | Frequencies | Diseases | NLS Informationsmedizin GmbH ENCoxsackie virus | Royal Rife Frequencies | Frequencies | Diseases | NLS Informationsmedizin GmbH EN
Frequency program with the assigned frequencies from the CAFL list The program was created according to the specifications of Dr. Royal Raymond Rife.…
https://www.frequenz-therapie.com/en/frequencies-diseases/royal-rife-frequencies/617/coxsackie-virus
Diagnosis of Viral myocarditis: Costs for treatment #211813 in Germany | BookingHealthDiagnosis of Viral myocarditis: Costs for treatment #211813 in Germany | BookingHealth
Diagnosis of Viral myocarditis (costs for program #211813) ✔ University Hospital RWTH Aachen ✔ Department of Gastroenterology, Metabolic Disorders and Internal Intensive Medicine ✔ BookingHealth.com
https://bookinghealth.com/rwth-university-hospital-aachen/diagnostic-programs/211813-diagnosis-of-viral-myocarditis.html
Diagnosis of Viral myocarditis: Costs for treatment #213137 in Germany | BookingHealthDiagnosis of Viral myocarditis: Costs for treatment #213137 in Germany | BookingHealth
Diagnosis of Viral myocarditis (costs for program #213137) ✔ DKD HELIOS Clinic Wiesbaden ✔ Department of Pediatrics ✔ BookingHealth.com
https://bookinghealth.com/dkd-helios-klinik-wiesbaden/diagnostic-programs/213137-diagnosis-of-viral-myocarditis.html
Or myocarditis.
For this cause, there could be many individuals who arent conscious they have the problem. To handle this deficiency, the experts viewed whether a biomarker for swelling in the brain may be used in the center. When researchers want a obvious picture of the level of harm from a brain damage, a PET can be used by them scan to consider elevated degrees of translocator protein 18 kDa, or TSPO. As it happens that TSPO exists in immune cells through the entire body. In the scholarly study, the researchers assessed degrees of TSPO in cells biopsied from sufferers with myocarditis and in mice with myocarditis linked to contact with coxsackievirus B3-the same virus that often results in the condition in human beings.Through this new mechanism of action, we hope to offer significant therapeutic benefits to patients with anemia connected with chronic kidney disease. Astellas has certified from FibroGen certain rights to FG-4592/ASP1517 in Japan, European countries, the Commonwealth of Independent Claims, ...
http://www.blackravenpipeband.net/2017/09/or-myocarditis/
Search Results from the VAERS DatabaseSearch Results from the VAERS Database
CDC Split Type: Write-up: Vaccine administration date 2/12/2007, varicella dose #2 and Gardisil dose #1 administered concurrently. No symptoms until March 4th when in AM noted by mother to have a cold/URI symptoms with cough. Emesis at 11 after soup at 10, napping when mom at home at 3 PM but difficult to arouse. Called 911 and started rescue breathing. Paramedics initially called in stable VSs but required active CPR on gurney by time came into ED. In disorganized vfib in ER-resuscd with PALS then consulted cardiology for ECMO. Cannulated for VA ECMO - on full flow support after 1.5 hours. Heart completely akinetic. Went to cath lab to get biopsies, CADs and assessment of integrity of heart with very poor tone/strength to heart muscle noted; presumed acute viral myocarditis. Has gotten IVIG. Cant assess neurologic function due to significant drug load. Remains with very disorganized rhythym today; to consider EPS study; also studying family for possible inherited rhythym disturbances. ...
http://www.medalerts.org/vaersdb/findfield.php?IDNUMBER=273426
Table - Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 - Volume 18, Number 10-October 2012 - Emerging Infectious...
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.. ...
https://wwwnc.cdc.gov/eid/article/18/10/12-0813-t1
Acute isolated myocarditis synonyms, acute isolated myocarditis antonyms - FreeThesaurus.comAcute isolated myocarditis synonyms, acute isolated myocarditis antonyms - FreeThesaurus.com
Synonyms for acute isolated myocarditis in Free Thesaurus. Antonyms for acute isolated myocarditis. 1 synonym for myocarditis: myocardial inflammation. What are synonyms for acute isolated myocarditis?
https://www.freethesaurus.com/acute+isolated+myocarditis
RCSB PDB - 4Q4W: High-resolution crystal structure of Coxsackievirus A24vRCSB PDB - 4Q4W: High-resolution crystal structure of Coxsackievirus A24v
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
http://www3.rcsb.org/structure/4Q4W
STD Testing West Coxsackie-STD Clinics in West Coxsackie, NYSTD Testing West Coxsackie-STD Clinics in West Coxsackie, NY
Find An STD Testing Center near you in West Coxsackie, New York. Discreet, and affordable STD Testing in the West Coxsackie, , New York area. Same day local 5 min. testing! 4,000 Testing Centers in the US.
http://awu-dam.org/std-testing-west-coxsackie-std-clinics-in-west-coxsackie-ny
Biblio | Centre for Heart Lung Innovation
F. S. Garmaroudi, Marchant, D., Si, X., Khalili, A., Bashashati, A., Wong, B. W., Tabet, A., Ng, R. T., Murphy, K., Luo, H., Janes, K. A., and McManus, B. M., Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection., Proc Natl Acad Sci U S A, vol. 107, no. 39, pp. 17053-8, 2010. ...
https://www.hli.ubc.ca/biblio?f%5Bauthor%5D=106
Normal ECHO 5 years after acute Myocarditis = no DCM as Sequelae ? - Heart Disease - MedHelpNormal ECHO 5 years after acute Myocarditis = no DCM as Sequelae ? - Heart Disease - MedHelp
I read horrible statistics about acute Myocarditis and deaths because of its complication: dilated cardiomyopathy (50+% of cases !!!??? Is this TRUE??) I had normal echo 5 years after acute Myocarditi...
https://www.medhelp.org/posts/Heart-Disease/Normal-ECHO-5-years-after-acute-Myocarditis--no-DCM-as-Sequelae-/show/2982540
Myocarditis Awareness, Research and Support - Myocarditis FoundationMyocarditis Awareness, Research and Support - Myocarditis Foundation
The Myocarditis Foundation raises awareness, promotes research and supports families affected by myocarditis. Learn more about our myocarditis organizations important work by visiting us online.
https://www.myocarditisfoundation.org/page/2/
Pediatric myocarditis - Notes ReadPediatric myocarditis - Notes Read
Treatment. There is no cure for myocarditis, although myocardial inflammation usually goes away on its own over time. The goal of treatment is to support cardiac activity and treat the underlying cause of myocarditis. Most children with this condition are hospitalized. Activity can tire the heart and is therefore frequently limited. Treatment may include:. ...
https://notesread.com/pediatric-myocarditis/
Frequently Asked Questions: COVID-19 Vaccines & Cases of Myocarditis | Lurie ChildrensFrequently Asked Questions: COVID-19 Vaccines & Cases of Myocarditis | Lurie Childrens
With recent reports that a small percentage of adolescents may have developed myocarditis after their COVID-19 vaccination, it is understandable to have questions about how this could affect your child.
https://www.luriechildrens.org/en/specialties-conditions/2019-novel-coronavirus-ncov/faqs-covid-19-vaccines-cases-of-myocarditis/
What to Know About Myocarditis and COVID-19 | Banner HealthWhat to Know About Myocarditis and COVID-19 | Banner Health
COVID-19 infection can lead to many side effects, including myocarditis. Before your child returns to the field, learn about the importance of the return to play protocol.
https://www.bannerhealth.com/healthcareblog/teach-me/myocarditis-and-covid-19-what-parents-should-know
MyocarditisMyocarditis
1997-2006 Healthboard.com. Healthboard.com is a purely informational website, and should not be used as a substitute for professional legal, medical or technical advice. ...
http://healthboard.com/Encyclopedia/Biotech/term/myocarditis.html
Pages that link to Myocarditis (peds) - WikEMPages that link to Myocarditis (peds) - WikEM
Please donate! Funds go solely to hosting and development costs that allow medical practitioners around the globe to freely access WikEM. ...
https://wikem.org/w/index.php?title=Special:WhatLinksHere/Myocarditis_
Coxsackie A virusCoxsackie A virus
May 2012). "Human SCARB2-dependent infection by coxsackievirus A7, A14, and A16 and enterovirus 71". Journal of Virology. 86 ( ... Sharma V, Rohrbough SN, Goessling LS, Brar AK, Eghtesady P (2019-11-19). "Abstract 17090: Perinatal Coxsackievirus B4 Infection ... Modlin JF (June 1988). "Perinatal echovirus and group B coxsackievirus infections". Clinics in Perinatology. 15 (2): 233-46. ... In most individuals, infection is asymptomatic or causes only mild symptoms. In others, infection produces short-lived (7-10 ...
https://en.wikipedia.org/wiki/Coxsackie_A_virus
CXB3SCXB3S
"Human astrocytic cells support persistent coxsackievirus B3 infection". Journal of Virology. 87 (22): 12407-21. doi:10.1128/JVI ... Coxsackie virus B3 sensitivity is a protein that is encoded by the CXB3S gene in human beings. Its lineage is: Catarrhini, ... "CXB3S coxsackie virus B3 sensitivity [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2018-11-11. "Entrez ... "coxsackievirus a24 variant: Topics by Science.gov". www.science.gov. Retrieved 2018-11-11. "Biology, Geography & Health ...
https://en.wikipedia.org/wiki/CXB3S
Bornholm diseaseBornholm disease
"Clinical features of coxsackievirus A4, B3, and B4 infections in children". PLOS ONE. 9 (2): e87391. Bibcode:2014PLoSO... ... The chest x-ray showed bilateral pleural effusions which resolved after infection. The erythrocyte sedimentation rate (ESR) and ... Schmidt NJ, Magoffin RL, Lennette EH (September 1973). "Association of group B coxsackie viruses with cases of pericarditis, ... An outbreak associated with coxsackievirus B1". JAMA. 270 (18): 2205-6. doi:10.1001/jama.270.18.2205. PMID 8411604. Weller, TH ...
https://en.wikipedia.org/wiki/Bornholm_disease
CoxsackievirusCoxsackievirus
Coxsackieviruses share many characteristics with poliovirus. With control of poliovirus infections in much of the world, more ... The coxsackieviruses subsequently were found to cause a variety of infections, including epidemic pleurodynia (Bornholm disease ... 2004). "Evidence for Coxsackievirus Infection in Primary Sjogren's Syndrome". Arthritis & Rheumatism. 50 (9): 2897-2902. doi: ... Dalldorf G, Gifford R (January 1954). "Susceptibility of gravid mice to Coxsackie virus infection". J. Exp. Med. 99 (1): 21-7. ...
https://en.wikipedia.org/wiki/Coxsackievirus
Delayed pubertyDelayed puberty
Acquired diseases include mumps orchitis, Coxsackievirus B infection, irradiation, chemotherapy, or trauma; all problems ...
https://en.wikipedia.org/wiki/Delayed_puberty
Keshan diseaseKeshan disease
Ren LQ, Li XJ, Li GS, Zhao ZT, Sun B, Sun F (November 2004). "Coxsackievirus B3 infection and its mutation in Keshan disease". ... Current research suggests that the lack of selenium results in a more virulent strain of the coxsackievirus becoming the ... In addition, an individual can experience eczema, psoriasis, arthritis, cataracts, alcoholism, and infections.[citation needed ... "Selenium deficiency and viral infection". J. Nutr. 133 (5 Suppl 1): 1463S-7S. doi:10.1093/jn/133.5.1463S. PMID 12730444. ...
https://en.wikipedia.org/wiki/Keshan_disease
Coxsackievirus and adenovirus receptorCoxsackievirus and adenovirus receptor
"Antiviral effect of Bosentan and Valsartan during coxsackievirus B3 infection of human endothelial cells". The Journal of ... "Effect of lovastatin on coxsackievirus B3 infection in human endothelial cells". Inflammation Research. 63 (4): 267-76. doi: ... "Interaction of coxsackievirus B3 with the full length coxsackievirus-adenovirus receptor". Nature Structural Biology. 8 (10): ... Coxsackievirus and adenovirus receptor (CAR) is a protein that in humans is encoded by the CXADR gene. The protein encoded by ...
https://en.wikipedia.org/wiki/Coxsackievirus_and_adenovirus_receptor
EnterovirusEnterovirus
"Persistent Coxsackievirus Infection: Enterovirus Persistence in Chronic Myocarditis and Dilated Cardiomyopathy". Group B ... and coxsackievirus A15 is the same serotype as coxsackievirus A11 and coxsackievirus A18 is the same serotype as coxsackievirus ... Enterovirus B includes coxsackievirus B1,2,3,4,5,6; coxsackievirus A9; echovirus 1-33 and enterovirus B69-113. Coxsackie B ... Enterovirus A include coxsackievirus A2, A3, A4, A5, A6, A7, A8, A10, A12, A14, A16 and enterovirus A71, A76 A89, A89, A90, A91 ...
https://en.wikipedia.org/wiki/Enterovirus
SCAR-FcSCAR-Fc
Herzum M, Ruppert V, Küytz B, Jomaa H, Nakamura I, Maisch B (July 1994). "Coxsackievirus B3 infection leads to cell death of ... sCAR-Fc (Soluble Receptor Analogue) is an experimental prophylactic treatment against coxsackievirus B3 (CVB) infections. ... September 2009). "Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic ... April 2004). "Soluble recombinant coxsackievirus and adenovirus receptor abrogates coxsackievirus b3-mediated pancreatitis and ...
https://en.wikipedia.org/wiki/SCAR-Fc
Selenium deficiencySelenium deficiency
... in combination with Coxsackievirus infection can lead to Keshan disease, which is potentially fatal. ...
https://en.wikipedia.org/wiki/Selenium_deficiency
HerpanginaHerpangina
... is a painful mouth infection caused by coxsackieviruses. Usually, herpangina is produced by one particular strain of coxsackie ... virus A (and the term "herpangina virus" refers to coxsackievirus A), but it can also be caused by coxsackievirus B or ...
https://en.wikipedia.org/wiki/Herpangina
Edwin Herman LennetteEdwin Herman Lennette
"Fatal Infection in an Infant Associated with Coxsackie Virus Group A, Type 16". New England Journal of Medicine. 268 (19): 1041 ... Schmidt, N. J.; Ho, H. H.; Lennette, E. H. (1975). "Propagation and isolation of group a coxsackieviruses in RD cells". Journal ... Lennette, E. H.; Koprowski, H. (1944). "Influence of age on the susceptibility of mice to infection with certain neurotropic ... Lennette and Koprowski published important findings on the influences of murine age on several murine viral infections and on ...
https://en.wikipedia.org/wiki/Edwin_Herman_Lennette
ULK1ULK1
November 2020). "Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes". ... Coxsackievirus B3 viral proteinase 3C can proteolytically process ULK1 by cleaving after glutamine (Q) residue 524, separating ...
https://en.wikipedia.org/wiki/ULK1
Endocardial fibroelastosisEndocardial fibroelastosis
They followed a series of epidemics of Coxsackie virus infection in their part of France. After each epidemic there were ... Jan 1997). "Viral infection of the myocardium in endocardial fibroelastosis. Molecular evidence for the role of mumps virus as ... They were able to culture Coxsackie virus from the tissues of many of the cases at all stages of this apparent progression. A ... Evidence gradually accumulated as to the role of infection as one such type of stress. The studies of Fruhling and colleagues ...
https://en.wikipedia.org/wiki/Endocardial_fibroelastosis
Coxsackie B virusCoxsackie B virus
"Persistent Coxsackievirus Infection: Enterovirus Persistence in Chronic Myocarditis and Dilated Cardiomyopathy". Group B ... Coxsackie B infections have been reported to account for nearly a quarter of all enterovirus infections. Nearly half of all ... Coxsackie B3 (CB3) infections are the most common enterovirus cause of myocarditis and sudden cardiac death. CB3 infection ... "Human coxsackievirus B4". NCBI Taxonomy Browser. 12073. "Human coxsackievirus B5". NCBI Taxonomy Browser. 12074. (CS1 maint: ...
https://en.wikipedia.org/wiki/Coxsackie_B_virus
Coxsackie B4 virusCoxsackie B4 virus
Infection can lead to beta cell apoptosis which increases the risk of insulitis. Coxsackievirus B4 is one of the six serotypes ... 2012). "Outcome of challenge with coxsackievirus B4 in young mice after maternal infection with the same virus during gestation ... A 2004 systematic review analyzing a possible association between coxsackievirus B infection and type 1 diabetes was ... Coxsackieviruses have two groups, A and B, each associated with different diseases. Coxsackievirus group A is known for causing ...
https://en.wikipedia.org/wiki/Coxsackie_B4_virus
STAT2STAT2
Some patients had also an onset of severe disease in infancy like infection with RSV, norovirus, coxsackievirus, adenovirus or ... CMV and VZV infections were severe as well in few patients. The virus infection was treated by high-dose of intravenous ... Therefore complete AR STAT2 deficiency usually causes disseminated LAV infection and recurrent natural viral infections. ... From the age 5 years, the frequency and severity of viral infections decreased and the age of 10 years the patients were mostly ...
https://en.wikipedia.org/wiki/STAT2
Chest painChest pain
Pericarditis: This condition can be the result of viral infection such as coxsackie virus and echovirus, tuberculosis, ...
https://en.wikipedia.org/wiki/Chest_pain
SORBS1SORBS1
In a mouse model of viral myocarditis due to Coxsackievirus infection, CAP/Ponsin stabilized antiviral type I interferon ...
https://en.wikipedia.org/wiki/SORBS1
Hand, foot, and mouth diseaseHand, foot, and mouth disease
... severe and are more likely to have neurologic or cardiac complications including death than infections caused by Coxsackievirus ... Coxsackievirus A16 is the most common cause of HFMD. Enterovirus 71 (EV-71) is the second-most common cause. Many other strains ... Other strains of coxsackievirus and enterovirus can also be responsible. Some people may carry and pass on the virus despite ... Infection in older children, adolescents, and adults is typically mild and lasts approximately 1 week, but may occasionally run ...
https://en.wikipedia.org/wiki/Hand,_foot,_and_mouth_disease
Vertically transmitted infectionVertically transmitted infection
... herpes simplex virus-2 or neonatal herpes simplex Other infections include: Parvovirus B19 Coxsackievirus Chickenpox (caused by ... For many infections, the baby is more at risk at particular stages of pregnancy. Problems related to perinatal infection are ... A vertically transmitted infection is an infection caused by pathogenic bacteria or viruses that use mother-to-child ... The term congenital infection can be used if the vertically transmitted infection persists after childbirth.[citation needed] ...
https://en.wikipedia.org/wiki/Vertically_transmitted_infection
DiabetesDiabetes
... syndrome Hyperthyroidism Hypothyroidism Pheochromocytoma Glucagonoma Infections Cytomegalovirus infection Coxsackievirus B ... Diabetic animals are more prone to infections. The long-term complications recognized in humans are much rarer in animals. The ... Petzold A, Solimena M, Knoch KP (October 2015). "Mechanisms of Beta Cell Dysfunction Associated With Viral Infection". Current ... Other complications include an impaired counterregulatory response to low blood sugar, infection, gastroparesis (which leads to ...
https://en.wikipedia.org/wiki/Diabetes
Coxsackievirus-induced cardiomyopathyCoxsackievirus-induced cardiomyopathy
In chronic murine infection, the percentage of infected cardiomyocytes are much lower. Unlike in the DMD, in coxsackievirus ... In a mouse model, at the acute stage (7 days after infection with coxsackievirus B3) approximately 10% of the myocytes are ... Coxsackievirus shows a cardiac tropism partly due to the high expression of coxsackievirus and adenovirus receptors (CAR) in ... acute enterovirus infections such as Coxsackievirus B3 have been identified as the cause of virally induced acute myocarditis, ...
https://en.wikipedia.org/wiki/Coxsackievirus-induced_cardiomyopathy
TelethoninTelethonin
... suggesting that Telethonin may be involved in the mechanism underlying Coxsackievirus B3 infection in acute and chronic ... "Proapoptotic protein Siva binds to the muscle protein telethonin in cardiomyocytes during coxsackieviral infection". ... "Proapoptotic protein Siva binds to the muscle protein telethonin in cardiomyocytes during coxsackieviral infection". ...
https://en.wikipedia.org/wiki/Telethonin
HeartHeart
This condition typically causes chest pain that may spread to the back, and is often caused by a viral infection (glandular ... fever, cytomegalovirus, or coxsackievirus). Fluid can build up within the pericardial sac, referred to as a pericardial ... but may also be caused by infection of the heart valves (endocarditis). In some parts of the world rheumatic heart disease is a ... and to protect the heart from infection. Heart tissue, like all cells in the body, needs to be supplied with oxygen, nutrients ...
https://en.wikipedia.org/wiki/Heart
Blueberry muffin babyBlueberry muffin baby
It can occur following infection of an unborn baby with rubella, cytomegalovirus, toxoplasmosis, or coxsackie virus. Other ... Other TORCH infections that can cause this rash include cytomegalovirus, herpes virus, and toxoplasma. Blood disorders, such as ... Syphilis: bacterial TORCH infection due to Treponema pallidum. Congenital syphilis can present with saber shins, saddle-shaped ... Rubella: viral TORCH infection associated with post-auricular and occipital lymphadenopathy in addition to a maculopapular rash ...
https://en.wikipedia.org/wiki/Blueberry_muffin_baby
Palmar erythemaPalmar erythema
Eczema and psoriasis Deep telangiectasias Coxsackievirus A infection (Hand, foot and mouth disease) Rocky Mountain spotted ...
https://en.wikipedia.org/wiki/Palmar_erythema
Oral mucosaOral mucosa
Hand, Foot, and Mouth Disease: A highly contagious viral infection which infects young children and is caused by Coxsackie ... Oral fungal infections are most commonly caused by different Candida species such as Candida Albicans, Candida Glabrata and ... Chicken Pox: A type of viral infection which is caused by Varicella Zoster Virus and presents in children. Numerous itchy ... They may be mistaken for papilloma or verrucous leukoplakia but are benign (1). Syphilis- Bacterial infection which is usually ...
https://en.wikipedia.org/wiki/Oral_mucosa
PericardiumPericardium
Pericarditis is often caused by a viral infection (glandular fever, cytomegalovirus, or coxsackievirus), or more rarely with a ... The pericardium sets the heart in mediastinum and limits its motion, protects it from infection, lubricates it and prevents ... It separates the heart from interference of other structures, protects it against infection and blunt trauma, and lubricates ... bacterial infection, but may also occur following a myocardial infarction. Pericarditis is usually a short-lived condition that ...
https://en.wikipedia.org/wiki/Pericardium
Infections associated with diseasesInfections associated with diseases
February 2014). "Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes". Diabetes ... Infections associated with diseases are those infections that are associated with possible infectious etiologies that meet the ... The history of infection and disease were observed in the 1800s and related to the one of the tick-borne diseases, Rocky ... COMMON INFECTIONS AND UNCOMMON DISEASE: ELUSIVE ASSOCIATIONS OF ENTEROVIRUSES AND TYPE I DIABETES MELLITUS". In Knobler, Stacey ...
https://en.wikipedia.org/wiki/Infections_associated_with_diseases
Gianotti-Crosti syndromeGianotti-Crosti syndrome
If there are any associated conditions like streptococcal infections, antibiotics may be required. List of cutaneous conditions ... Other viruses implicated are hepatitis A virus, hepatitis C virus, cytomegalovirus, coxsackievirus, adenovirus, enterovirus, ... August 2004). "Gianotti-Crosti syndrome caused by acute hepatitis B virus genotype D infection". Internal Medicine (Tokyo, ... 389 is a reaction of the skin to a viral infection. Hepatitis B virus and Epstein-Barr virus are the most frequently reported ...
https://en.wikipedia.org/wiki/Gianotti–Crosti_syndrome
G. D. HsiungG. D. Hsiung
This laboratory has since played an important role in diagnosing serious viral infections in the region, such as severe acute ... coxsackievirus and echoviruses. This work also revealed that echovirus-10 had distinct characteristics and should be removed ... She worked extensively on the pathogenesis and treatment of herpesvirus infections, including genital herpes latency, in both ... in the guinea pig correlated with congenital CMV in humans and provided an important model for this infection. In the late ...
https://en.wikipedia.org/wiki/G._D._Hsiung
MacropsiaMacropsia
Patients with Coxsackievirus B1 have reported numerous symptoms of Alice in Wonderland Syndrome, the most common of which being ... Cinbis M, Aysun S: Alice in Wonderland syndrome as an initial manifestation of Epstein-Barr virus infection (case report). Br J ... With regard to drug-induced or virus-induced macropsia, once the underlying problem, either drug abuse or viral infection, is ... Abnormal magnetic resonance imaging in a child with Alice in Wonderland syndrome following Epstein-Barr virus infection No to ...
https://en.wikipedia.org/wiki/Macropsia
PicornavirusPicornavirus
The whole of replication occurs within the host-cell cytoplasm and infection can even happen in cells that do not contain a ... Partial crystal structures for VPgs of foot and mouth disease virus and coxsackie virus B3 suggest that there may be two sites ... October 2008). "The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg ... As little as 30 minutes after initial infection, though, cell protein synthesis declines to almost zero output - essentially ...
https://en.wikipedia.org/wiki/Picornavirus
Alice in Wonderland syndromeAlice in Wonderland syndrome
In some instances, Alice in Wonderland syndrome was reported to be associated with an Influenza A infection and it is possible ... Some of these infectious agents included Epstein-Barr virus, Varicella Zoster virus, Influenza, Zika, Coxsackievirus, ... Cinbis M, Aysun S (1992). "Alice in Wonderland syndrome as an initial manifestation of Epstein-Barr virus infection". Br J ... or viral encephalitis caused by Epstein-Barr virus infection. It is also theorized that it can be caused by abnormal amounts of ...
https://en.wikipedia.org/wiki/Alice_in_Wonderland_syndrome
2018 Malaysia HFMD outbreak2018 Malaysia HFMD outbreak
As infection rates increased among children, the local health department of Penang ordered all supermarkets and shopping ... Over 50,000 cases of hand, foot and mouth disease (HFMD) stemming from the Coxsackie virus have been reported since the ... in Malaysia was first reported in the state of Sarawak in 1997 where between 28 and 31 children died as a result of infection ... infected with the disease did not go to school and to seek immediate treatment if their children showed signs of infection. The ...
https://en.wikipedia.org/wiki/2018_Malaysia_HFMD_outbreak
Oncolytic virusOncolytic virus
Coxsackievirus A21 is being developed by Viralytics under trade name Cavatak. Coxsackievirus A21 belongs to Enterovirus C ... The infection of cells with viruses containing the genes for angiostatin and endostatin synthesis inhibited tumour growth in ... Though the cause is not fully understood, they are thought likely to be a result of a sudden immune response or infection. ... Attenuation of the virus by engineering a deletion of Met-51 of the matrix protein ablates virtually all infection of normal ...
https://en.wikipedia.org/wiki/Oncolytic_virus
Hopkins syndromeHopkins syndrome
Its cause has not been established, but its association with asthma exacerbations (usually with a respiratory infection as a ... In several cases, anti-viral antibody titers for echovirus, enterovirus, coxsackievirus and poliovirus types 1, 2 and 3 were ... Acharya, AB; Lakhani, PK (1997). "Hopkins syndrome associated with Mycoplasma infection". Pediatric Neurology. 16 (1): 54-5. ... trigger) has led to suspicion that the initial viral insult that causes the respiratory infection is also implicated in the ...
https://en.wikipedia.org/wiki/Hopkins_syndrome
Picornain 3CPicornain 3C
Coxsackievirus is shed through stool and bodily fluids and is prevalent in children but can infection occur in adults. Symptoms ... Coxsackievirus primarily infects mucosal and epithelial membranes. 3C proteinase activity in coxsackievirus causes apoptosis in ... Chau DH, Yuan J, Zhang H, Cheung P, Lim T, Liu Z, Sall A, Yang D (March 2007). "Coxsackievirus B3 proteases 2A and 3C induce ... Chau DH, Yuan J, Zhang H, Cheung P, Lim T, Liu Z, Sall A, Yang D (March 2007). "Coxsackievirus B3 proteases 2A and 3C induce ...
https://en.wikipedia.org/wiki/Picornain_3C
Herpesviral encephalitisHerpesviral encephalitis
Hill JM, Zhao Y, Clement C, Neumann DM, Lukiw WJ (October 2009). "HSV-1 infection of human brain cells induces miRNA-146a and ... coxsackievirus, etc.). Whitley RJ (September 2006). "Herpes simplex encephalitis: adolescents and adults". Antiviral Research. ... Kropp RY, Wong T, Cormier L, Ringrose A, Burton S, Embree JE, Steben M (June 2006). "Neonatal herpes simplex virus infections ... Rarely, treated individuals can have relapse of infection weeks to months later. There is evidence that aberrant inflammation ...
https://en.wikipedia.org/wiki/Herpesviral_encephalitis
ICAM-1ICAM-1
With the roles of ICAM-1 in cell-cell adhesion, extravasation, and infection more fully understood, a potential role for ICAM-1 ... ICAM-1 is the primary entry receptor for Coxsackievirus A21, an oncolytic virus (brand name Cavatak, being developed by ... Sep 2000). "Permissive factors for HIV-1 infection of macrophages". Journal of Leukocyte Biology. 68 (3): 303-10. doi:10.1189/ ... "Viral targeting of non-muscle invasive bladder cancer and priming of anti-tumour immunity following intravesical Coxsackievirus ...
https://en.wikipedia.org/wiki/ICAM-1
Craig E. CameronCraig E. Cameron
The viruses that Cameron studied included the rhinovirus, the common cold and coxsackievirus. Cameron moved to Case Western ... His research considers RNA virus infections. Cameron developed lethal mutagenesis; an alternative mechanism of action of ...
https://en.wikipedia.org/wiki/Craig_E._Cameron
Stevens-Johnson syndromeStevens-Johnson syndrome
The second most common cause of SJS and TEN is infection, particularly in children. This includes upper respiratory infections ... Viral diseases reported to cause SJS include: herpes simplex virus (possibly; is debated), AIDS, coxsackievirus, influenza, ... Recent upper respiratory tract infections have been reported by more than half of patients with SJS. Bacterial infections ... antipyretics and analgesics to manage infections can make it difficult to identify if cases were caused by the infection or ...
https://en.wikipedia.org/wiki/Stevens–Johnson_syndrome
List of vaccine topicsList of vaccine topics
Kim, D. S.; Nam, J. H. (2010). "Characterization of attenuated coxsackievirus B3 strains and prospects of their application as ... Human Brucella abortus RB51 Infections Caused by Consumption of Unpasteurized Domestic Dairy Products - United States, 2017- ... Frontiers in Cellular and Infection Microbiology. 2: 16. doi:10.3389/fcimb.2012.00016. PMC 3417391. PMID 22919608. Guilherme, L ...
https://en.wikipedia.org/wiki/List_of_vaccine_topics
Skin infectionSkin infection
It is caused by the human enteroviruses and coxsackieviruses, a positive-sense single-stranded RNA viruses. Stevens DL, Bisno ... They comprise a category of infections termed skin and skin structure infections (SSSIs), or skin and soft tissue infections ( ... a potentially life-threatening infection. Fungal skin infections may present as either a superficial or deep infection of the ... A skin infection is an infection of the skin in humans and other animals, that can also affect the associated soft tissues such ...
https://en.wikipedia.org/wiki/Skin_infection
AdenoviridaeAdenoviridae
Most infections with adenovirus result in infections of the upper respiratory tract. Adenovirus infections often present as ... The two currently established receptors are: CD46 for the group B human adenovirus serotypes and the coxsackievirus/adenovirus ... Type 1 infection can also cause respiratory and eye infections. CAdV-1 also affects foxes (Vulpes vulpes and Vulpes lagopus) ... and-rarely-even previously healthy people can die of these infections. This may be because sometimes adenoviral infection can ...
https://en.wikipedia.org/wiki/Adenoviridae
Chest pain in childrenChest pain in children
Infection with Haemophilus influenzae can cause chest pain. Since most causes of pediatric and adolescent chest pain are not ... broken rib trauma scoliosis muscle strain post surgical pain asthma airway foreign body chronic cough Coxsackievirus Pleural ...
https://en.wikipedia.org/wiki/Chest_pain_in_children
PancreatitisPancreatitis
Complications may include infection, bleeding, diabetes mellitus, or problems with other organs. The two most common causes of ... A number of infectious agents have been recognized as causes of pancreatitis including: Viruses Coxsackie virus Cytomegalovirus ... Other causes include direct trauma, certain medications, infections such as mumps, and tumors. Chronic pancreatitis may develop ... and infection. This happens in approximately 3% of cases or almost 60% of cases involving more than two pseudocysts and gas in ...
https://en.wikipedia.org/wiki/Pancreatitis
Viral cardiomyopathyViral cardiomyopathy
Coxsackievirus-induced cardiomyopathy Myocarditis Pericarditis Vaccine adverse event Schultz, Jason C.; Hilliard, Anthony A.; ... Hundreds of studies have reported myocarditis/myopericarditis caused by Covid-19 infection in living patients, with a male ... Viral cardiomyopathy occurs when viral infections cause myocarditis with a resulting thickening of the myocardium and dilation ... Myocarditis may result from a direct viral infection of the myocardium. Cardiovascular biomarkers like troponin, lactate ...
https://en.wikipedia.org/wiki/Viral_cardiomyopathy
IonophoreIonophore
Zinc ionophores have been shown to inhibit replication of various viruses in vitro, including coxsackievirus, equine arteritis ... Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice". EBioMedicine. 24: 189-194. doi:10.1016/j. ... Inhibits Zika Virus Infection in Different Cell Models". Viruses. 8 (12): 322. doi:10.3390/v8120322. PMC 5192383. PMID 27916837 ... antibiotics for respiratory infections with sore throat: An antibiotic stewardship perspective". Journal of Clinical Pharmacy ...
https://en.wikipedia.org/wiki/Ionophore
PleconarilPleconaril
In Coxsackievirus, Pleconaril efficiency correlates to the susceptibility of CVB3 with the amino acid at position 1092 in the ... Ronald B. Turner; J. Owen Hendley (2005). "Virucidal hand treatments for prevention of rhinovirus infection". J Antimicrob ... The wild type resistance frequency to pleconaril was about 5×10−5. Coxsackievirus B3(CVB3) strain Nancy and other mutants carry ... Rotbart, HA (February 2002). "Treatment of picornavirus infections". Antiviral Research. 53 (2): 83-98. doi:10.1016/s0166-3542( ...
https://en.wikipedia.org/wiki/Pleconaril
Acute hemorrhagic conjunctivitisAcute hemorrhagic conjunctivitis
The Coxsackievirus is another member of the genus of viruses called Enterovirus and family of the viruses Picornaviridae. Its ... Within one to two days of infection, symptoms will begin to become apparent. Enterovirus 70 is a member of the genus of viruses ... There are 57 variants of this virus, that each cause 5-10% of upper respiratory infections in humans. These viruses are some of ... It is an antigenic variant of the Coxsackievirus A24. It was studied independently for the first time in Singapore in 1970. ...
https://en.wikipedia.org/wiki/Acute_hemorrhagic_conjunctivitis
Increased Detections and Severe Neonatal Disease Associated with Coxsackievirus B1 Infection --- United States, 2007Increased Detections and Severe Neonatal Disease Associated with Coxsackievirus B1 Infection --- United States, 2007
Coxsackievirus B1 infection in infants less than 2 months of age. Am J Perinatol 1998;15:155--9. ... Neonatal enterovirus infections: emphasis on risk factors of severe and fatal infections. Pediatr Infect Dis J 2003;22:889--94. ... Increased Detections and Severe Neonatal Disease Associated with Coxsackievirus B1 Infection --- United States, 2007. ... Perinatal echovirus infection: insights from a literature review of 61 cases of serious infection and 16 outbreaks in nurseries ...
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5720a4.htm
Coxsackievirus Infections (for Parents) - Print Version - Nemours (XML)Coxsackievirus Infections (for Parents) - Print Version - Nemours (XML)
Coxsackievirus Infections. What Are Coxsackievirus Infections?. Coxsackieviruses are part of the enterovirus family of viruses ... Can Coxsackievirus Infections Be Prevented?. There is no vaccine to prevent coxsackievirus infection. Hand washing is the best ... How Long Do Coxsackievirus Infections Last?. How long the infection lasts can vary. Kids who only have a fever may see their ... How Are Coxsackievirus Infections Treated?. Depending on the type of infection and symptoms, the doctor may prescribe medicines ...
https://www.kidshealth.org/NemoursXML/en/parents/coxsackie.html?view=ptr&WT.ac=p-ptr
Coxsackievirus Infections in Children - HealthyChildren.orgCoxsackievirus Infections in Children - HealthyChildren.org
infections~American Academy of Pediatrics (AAP) describes treatment and prevention of enteroviruses. ... Muscle infections. Infection with coxsackievirus types B3, B5, or B6 can cause repeated sharp spasms in the muscles located ... Heart infections. Infections with coxsackievirus types B2 to B5 can cause swelling and inflammation of the hearts muscle and ... Infections are most common during summer and early fall.. How do coxsackieviruses spread?. Coxsackieviruses can be spread ...
https://www.healthychildren.org/english/health-issues/conditions/infections/Pages/Coxsackieviruses-and-Other-Enterovirus-Infections.aspx
Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China - Volume 18, Number 5-May 2012 - Emerging...
Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China. Emerging Infectious Diseases. 2012;18(5):821- ... Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China On This Page ... Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China. Emerg Infect Dis. 2012;18(5):821-824. https ... Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China. Volume 18, Number 5-May 2012 ...
https://wwwnc.cdc.gov/eid/article/18/5/11-1376
PCR plus phylogenetics pin down group A coxsackievirus infections | Journal of Clinical PathologyPCR plus phylogenetics pin down group A coxsackievirus infections | Journal of Clinical Pathology
Group A coxsackieviruses are difficult to culture. By using PCR and phylogenetic analysis the researchers had found that ... Throat swabs cultured from 246 children with acute summertime febrile illness yielded 33 enteroviruses-coxsackievirus A16 from ... from Japan has confirmed the potential of PCR and phylogenetic analysis to enable identification of group A coxsackieviruses ... of the positive samples with other sequences and phylogenetic analysis showed that those positive for group A coxsackieviruses ...
https://jcp.bmj.com/content/56/1/55
Infections with Coxsackie virus B5 in six midwestern StatesInfections with Coxsackie virus B5 in six midwestern States
Title : Infections with Coxsackie virus B5 in six midwestern States Personal Author(s) : Chin, Tom D. Y.;Greene, John C.;Wenner ...
https://stacks.cdc.gov/view/cdc/73008
Coxsackieviruses Treatment & Management: Medical Care, Surgical Care, ConsultationsCoxsackieviruses Treatment & Management: Medical Care, Surgical Care, Consultations
Coxsackieviruses belong to the family Picornaviridae and the genus Enterovirus, which also includes poliovirus and echovirus. ... Effect of Coxsackievirus B4 Infection on the Thymus: Elucidating Its Role in the Pathogenesis of Type 1 Diabetes. ... There are no routine antiviral drugs used to treat infections caused by coxsackieviruses. [23] However, both intravenous immune ... Nekoua MP, Alidjinou EK, Hober D. Persistent coxsackievirus B infection and pathogenesis of type 1 diabetes mellitus. Nat Rev ...
https://www.medscape.com/answers/215241-93750/which-dietary-modifications-are-needed-for-patients-with-coxsackievirus-infection
Superoxide production by NADPH oxidase intensifies macrophage antiviral responses during diabetogenic coxsackievirus infectionSuperoxide production by NADPH oxidase intensifies macrophage antiviral responses during diabetogenic coxsackievirus infection
Upon infection with a suspected diabetogenic virus, Coxsackievirus B3 (CB3), NOD.Ncf1m1J mice remained resistant to virus- ... Coxsackievirus B infections are suspected environmental triggers of type 1 diabetes (T1D) and macrophage antiviral responses ... Superoxide production by NADPH oxidase intensifies macrophage antiviral responses during diabetogenic coxsackievirus infection ... We report that superoxide production following CB3 infection may exacerbate pancreatic b cell destruction in T1D by influencing ...
https://scholars.uab.edu/display/pub1576956
Figure 1 - Ambulatory Pediatric Surveillance of Hand, Foot and Mouth Disease as Signal of an Outbreak of Coxsackievirus A6...
Ambulatory Pediatric Surveillance of Hand, Foot and Mouth Disease as Signal of an Outbreak of Coxsackievirus A6 Infections, ... Yang F, Yuan J, Wang X, Li J, Du J, Su H, Severe hand, foot, and mouth disease and coxsackievirus A6-Shenzhen, China. Clin ... Lu QB, Zhang XA, Wo Y, Xu HM, Li XJ, Wang XJ, Circulation of Coxsackievirus A10 and A6 in hand-foot-mouth disease in China, ... Wei SH, Huang YP, Liu MC, Tsou TP, Lin HC, Lin TL, An outbreak of coxsackievirus A6 hand, foot, and mouth disease associated ...
https://wwwnc-origin.cdc.gov/eid/article/22/11/16-0590-f1
Hand-foot-mouth disease: MedlinePlus Medical EncyclopediaHand-foot-mouth disease: MedlinePlus Medical Encyclopedia
Hand-foot-mouth disease is a common viral infection that most often begins in the throat. ... Antibiotics do not work because the infection is caused by a virus. (Antibiotics treat infections caused by bacteria, not ... Coxsackieviruses, echoviruses, and numbered enteroviruses (EV-A71, EVD-68, EVD-70). In: Bennett JE, Dolin R, Blaser MJ, eds. ... Teens and adults can sometimes get the infection. HFMD usually occurs in the summer and early fall. ...
https://medlineplus.gov/ency/article/000965.htm
Hand, Foot and Mouth Disease (Coxsackie viral infection)Hand, Foot and Mouth Disease (Coxsackie viral infection)
Does a prior infection with Coxsackie virus make a person immune?. Specific immunity can occur, but a second episode is ... Hand, foot and mouth disease is a viral infection caused by a strain of Coxsackie virus. It causes a blister-like rash that, as ... More serious infections have been seen recently with a certain strain of Coxsackie viral infection in Indonesia. ... You are Here: Home Page , Communicable Disease , Hand, Foot and Mouth Disease (Coxsackie viral infection) ...
https://www.health.ny.gov/diseases/communicable/hand_foot_mouth/fact_sheet.htm?fbclid=IwAR08R9JuntRvtnIoSEVHgWGQdJuETAnbKhPWSCopmVE0U6H9bleSdOPvjvY
Characterization of a putative ancestor of coxsackievirus B5Characterization of a putative ancestor of coxsackievirus B5
... coxsackievirus B5 (CVB5) exists as circulating heterogeneous populations of genetic variants. In this study, we present the ... Coxsackievirus Infections / virology * Enterovirus B, Human / classification * Enterovirus B, Human / genetics* * Enterovirus B ... Characterization of a putative ancestor of coxsackievirus B5 J Virol. 2010 Oct;84(19):9695-708. doi: 10.1128/JVI.00071-10. Epub ... Like other RNA viruses, coxsackievirus B5 (CVB5) exists as circulating heterogeneous populations of genetic variants. In this ...
https://pubmed.ncbi.nlm.nih.gov/20631132/
Acute Hemorrhagic Edema of Infancy Differential DiagnosesAcute Hemorrhagic Edema of Infancy Differential Diagnoses
Acute hemorrhagic edema of infancy associated with Coxsackie virus infection. Arch Pediatr. Apr 2018. 25(3):244. [QxMD MEDLINE ... Di Lernia V, Lombardi M, Lo Scocco G. Infantile acute hemorrhagic edema and rotavirus infection. Pediatr Dermatol. 2004 Sep-Oct ...
https://emedicine.medscape.com/article/1112590-differential
Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)
Categories: Coxsackievirus Infections Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Coxsackievirus+Infections&parentid=9638&catid=7241
Echovirus Infection Workup: Laboratory Studies, Imaging Studies, Other TestsEchovirus Infection Workup: Laboratory Studies, Imaging Studies, Other Tests
Coxsackievirus B5 infection and aseptic meningitis in neonates and children. Am J Dis Child. 1975 Mar. 129(3):321-5. [QxMD ... Perinatal echovirus and group B coxsackievirus infections. Clin Perinatol. 1988 Jun. 15 (2):233-46. [QxMD MEDLINE Link]. ... encoded search term (Echovirus Infection) and Echovirus Infection What to Read Next on Medscape ... Echovirus Infection Workup. Updated: Jun 14, 2019 * Author: Madhu Chhanda Choudhary, MD; Chief Editor: Michael Stuart Bronze, ...
https://emedicine.medscape.com/article/216564-workup
Frontiers | 5-Hydroxytryptamine, Glutamate, and ATP: Much More Than NeurotransmittersFrontiers | 5-Hydroxytryptamine, Glutamate, and ATP: Much More Than Neurotransmitters
Persistent infection of human pancreatic cells with Coxsackievirus B4 is cured by fluoxetine. Antiviral. Res. 116, 51-54. doi: ... SARS-CoV-2 infection leads to COVID-19 that consists of 3 phases that are not manifested in all patients: asymptomatic or low- ... Di Virgilio, F., Dal Ben, D., Sarti, A. C., Giuliani, A. L., and Falzoni, S. (2017). The P2X7 Receptor in Infection and ... Surely, P2X7 receptor is involved in regulating infection and inflammation but there is controversy as how to pharmacologically ...
https://www.frontiersin.org/articles/10.3389/fcell.2021.667815/full
Volume 98, Issue 8 | Acta Dermato-VenereologicaVolume 98, Issue 8 | Acta Dermato-Venereologica
Wells Syndrome Associated with Coxsackievirus A6 Infection. Yuta Yoshii, Takahiro Ishikawa, Takichi Munetsugu, Aya Nishizawa, ...
https://www.medicaljournals.se/acta/content/issue/98-8
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Whole-Genome Analysis of Coxsackievirus B3 Reflects Its Genetic Diversity in China and Worldwide | Research SquareWhole-Genome Analysis of Coxsackievirus B3 Reflects Its Genetic Diversity in China and Worldwide | Research Square
Background Coxsackievirus B3 (CVB3) has emerged as an active pathogen in myocarditis, aseptic meningitis, hand, foot, and mouth ... Coxsackievirus B3-associated aseptic meningitis: An emerging infection in Hong Kong. J Med Virol. 2011;83:483-9. ... Clinical Features of Coxsackievirus A4, B3 and B4 Infections in Children. PLoS One. 2014;9:e87391. ... Molecular epidemiology of coxsackievirus B3 infection in Spain, 2004-2014. Arch Virol. 2016;161:1365-70. ...
https://www.researchsquare.com/article/rs-1038176/v1
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TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease ...
https://www.bmglabtech.com/ja/pherastar-fsx/
Expert Review of the Vieques Heart Study Summary Report for the Vieques Heart Study Expert Panel Review | Vieques, Puerto Rico ...Expert Review of the Vieques Heart Study Summary Report for the Vieques Heart Study Expert Panel Review | Vieques, Puerto Rico ...
In response, a PSM investigator doubted that a widespread pericarditis-causing viral infection (e.g., coxsackievirus) could ... coxsackievirus infections) are difficult to detect, especially among populations with limited access to medical care. In short ... A panelist added that gathering information on past viral infections is extremely difficult and he doubted whether an alternate ... Commenting on these concerns, an ATSDR scientist said that some infections that might cause pericardial thickening (e.g., ...
http://www.atsdr.cdc.gov/sites/vieques/heart_study_summary.html
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TRIM7 restricts coxsackievirus and norovirus infection by detecting the C-terminal glutamine generated by 3C protease ...
https://www.esrf.fr/id29
Viruses and Diabetes Research Group | School of Clinical Medicine - UNSW SydneyViruses and Diabetes Research Group | School of Clinical Medicine - UNSW Sydney
Coxsackievirus B5 Infection Induces Dysregulation of microRNAs Predicted to Target Known Type 1 Diabetes Risk Genes in Human ... Maternal virus infections in pregnancy and type 1 diabetes in their offspring: Systematic review and meta-analysis of ... Weve shown that enterovirus infection often precedes islet autoimmunity and the increased risk of type 1 diabetes , however ... particularly enterovirus infections, as environmental triggers of islet autoimmunity (also known as stages 1-2 diabetes, which ...
https://www.unsw.edu.au/medicine-health/our-schools/clinical-medicine/research-impact/research-groups/cardiac-vascular-metabolic-medicine/viruses-diabetes-research-group
Can mouth ulcer cause fever in babies? - Xshotpix.comCan mouth ulcer cause fever in babies? - Xshotpix.com
Mouth sores can be linked to certain infections including coxsackievirus infections. They can also represent canker sores. Some ... Signs of infection around a mouth sore (pus, drainage, or swelling) Signs of dehydration (very dark or little urine, very ... 8 Thrush does not typically cause a fever, although some infants could have a coexisting viral infection that causes elevation ... If an infection is causing the ulcers, your child might also have a fever. ...
https://www.xshotpix.com/can-mouth-ulcer-cause-fever-in-babies/
Deaconess - Your Health - Resources, Information, and HelpDeaconess - Your Health - Resources, Information, and Help
Hand-foot-and-mouth disease is a viral infection most commonly caused by coxsackievirus. Although it can be seen in any age ... Ear Infections in Children. Dr. Jung Smith, Family Medicine Physician. Did you know that more than three out of four children ... Veronica M., Infection Prevention and Employee Health at The Womens Hospital Why should we immunize? The CDC recommends that ... Sexually Transmitted Infections: A Reality That Must Be Discussed. Rebecca Hopper, MD, Pediatrics/Internal Medicine, Deaconess ...
https://deaconess.com/Your-Health/Your-Health-Blog/July-2015
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Infections with Coxsackie virus B5 in six midwestern States Cite CITE. Title : Infections with Coxsackie virus B5 in six ...
https://stacks.cdc.gov/view/cdc/73005
Glucose-6-phosphate dehydrogenase deficiency enhances enterovirus 71 infection | Microbiology SocietyGlucose-6-phosphate dehydrogenase deficiency enhances enterovirus 71 infection | Microbiology Society
Mechanistically, viral infection led to increased oxidative stress, as indicated by increased dichlorofluorescein fluorescence ... infection. Compared with their normal counterparts, G6PD-deficient cells supported EV71 replication more efficiently and showed ... Vitamin E deficiency intensifies the myocardial injury of coxsackievirus B3 infection of mice. J Nutr 124:345-358 ... Cai J., Chen Y., Seth S., Furukawa S., Compans R. W., Jones D. P. 2003; Inhibition of influenza infection by glutathione. Free ...
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.2008/001404-0
quasispeciesquasispecies
The 1-to-Stop Coxsackieviruses were attenuated in a mouse model of infection. Furthermore, mice infected with 1-to-Stop virus ... However, the multiplicity of infection (MOI) that was used should have only resulted in multiple infections in 15% of the cells ... That infection proceeds at all is due to incorporation of the viral protein vif in the virus particles. Vif binds APOBEC3G, ... APOBEC3G constitutes an intrinsic defense against HIV-1 infection, because extensive mutation of the viral DNA reduces viral ...
https://www.virology.ws/tag/quasispecies/
JYX - The role of calpains in enterovirus infectionJYX - The role of calpains in enterovirus infection
The inhibition of calpains before 120 min post-infection inhibited both Echovirus 1 and Coxsackievirus B3 infection. The ... Aim of this study is to investigate the role of calpains in Echovirus 1 and Coxsackievirus B3 infections. An array of ... calpain CVB3 EV1 infection timetable picornavirus polyprotein virukset infektiot enterovirukset viruses infections ... Detecting Enterovirus Infection in Type 1 Diabetic Pancreas Tissue Using Immuno-Electron Microscopy  Lommi, Sara (2019) ...
https://jyx.jyu.fi/handle/123456789/68784
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EnterovirusesEchovirusVirusesEncephalitisViral infectionsHerpanginaCoxsackie virusRespiratorySerotypesConjunctivitisDiagnosisEnteroviral infectionsSymptomsVaccineInfluenzaInflammationEnterovirus 71FeverMeningitisTreat infections causedStrainsAntiviral drugsInfantsContagiousEnvironmental triggersCVB3MyocardialSevereOxidative stressSusiBacteriaDiseasesMumps infectionHerpesHFMDIslet autoimmunitySerious infectionsNeonatalAntibodySignsCharacteristicGroupHumanMiceMildImmuneDiabetesNewbornsRashThroat
Enteroviruses8
  • Coxsackieviruses are one of the four kinds of viruses (along with polioviruses, echoviruses, and numbered enteroviruses) that together are known as enteroviruses. (healthychildren.org)
  • There is no licensed specific treatment available for coxsackieviruses or any of the other types of enteroviruses. (healthychildren.org)
  • Throat swabs cultured from 246 children with acute summertime febrile illness yielded 33 enteroviruses-coxsackievirus A16 from a case of herpangina, 32 enteroviruses from children with pharyngitis/tonsillitis-but none from children with febrile seizures. (bmj.com)
  • By using PCR and phylogenetic analysis the researchers had found that enteroviruses were associated with summertime febrile seizures in children and wanted to see whether group A coxsackieviruses were associated with other summertime febrile illnesses. (bmj.com)
  • Echoviruses of Enteroviruses Infection. (medscape.com)
  • Coxsackieviruses, echoviruses, and newer enteroviruses. (medscape.com)
  • Neonatal infection Enteroviruses, along with rhinoviruses (see Common Cold) and human parechoviruses, are a genus of picornaviruses ( pico , or small, RNA viruses). (merckmanuals.com)
  • types of enteroviruses like coxsackieviruses. (cdc.gov)
Echovirus7
  • Typical clinical presentations include encephalomyocarditis (characteristic of group B coxsackieviruses) and hemorrhage-hepatitis syndrome (typical of echovirus 11) ( 1,2 ). (cdc.gov)
  • For instance, in France and Spain, echovirus 11 and echovirus 6 are the predominant serotypes in patients with enterovirus respiratory infections ( 2 , 3 ). (cdc.gov)
  • Tämän Pro Gradu -tutkielman tavoitteena oli selvittää millainen rooli calpaineilla on Echovirus 1 ja Coxsackievirus B3 -infektioissa. (jyu.fi)
  • Calpainien toiminnan estäminen ennen 120 minuutin aikapistettä esti sekä Echovirus 1, että Coxsackievirus B3 -infektion. (jyu.fi)
  • Aim of this study is to investigate the role of calpains in Echovirus 1 and Coxsackievirus B3 infections. (jyu.fi)
  • The inhibition of calpains before 120 min post-infection inhibited both Echovirus 1 and Coxsackievirus B3 infection. (jyu.fi)
  • Though the cue for genetic predisposition has been elucidated, evidence also points to involvement of enterovirus (EV) infection, including viruses such as poliovirus, Coxsackievirus A, Coxsackievirus B, and echovirus. (infectioncontroltoday.com)
Viruses7
  • Coxsackieviruses are part of the enterovirus family of viruses (which also includes polioviruses and hepatitis A virus ) that can live in the human digestive tract. (kidshealth.org)
  • Thus, during some years, these 2 viruses cause a substantial proportion of enterovirus-associated adult acute respiratory tract infections. (cdc.gov)
  • Several small trials have investigated the clinical efficacy of pleconaril in the treatment of coxsackieviruses and other viruses. (medscape.com)
  • Antibiotics treat infections caused by bacteria, not viruses. (medlineplus.gov)
  • Like other RNA viruses, coxsackievirus B5 (CVB5) exists as circulating heterogeneous populations of genetic variants. (nih.gov)
  • Enterovirus infections are caused by many different viruses. (msdmanuals.com)
  • Adenoviruses are a family of related viruses which cause mild infections in people and which have been converted into gene transfer vectors by blocking their ability to replicate in cells. (ukri.org)
Encephalitis3
  • [ 23 ] However, both intravenous immune globulin (IVIG) and the antiviral agent pleconaril have been investigated for possible efficacy in treating enteroviral infections, particularly in infants and immunocomprimised individuals with severe enteroviral syndromes such as encephalitis and myocarditis. (medscape.com)
  • In a literature review of IVIG use in the setting of enteroviral encephalitis, the authors noted that interleukin and interferon levels typically were elevated in severe enteroviral infection and were subsequently lowered after IVIG administration. (medscape.com)
  • Johnstone JA, Ross CA, Dunn M. Meningitis and encephalitis associated with mumps infection. (medscape.com)
Viral infections5
  • There is debate as to any congenital disorders related to Coxsackie viral infections and pregnancy. (ny.gov)
  • Of the diverse spectrum of environmental factors associated with type 1 diabetes, the greatest body of molecular and epidemiological data support the contribution of viral infections, particularly enterovirus infections, as environmental triggers of islet autoimmunity (also known as stages 1-2 diabetes, which precede the clinical onset of type 1 diabetes). (edu.au)
  • The role of oxidative stress in viral infections. (microbiologyresearch.org)
  • Finally, I provide clues for differentiating the various viral infections characterized by umbilicated lesions. (consultant360.com)
  • Potential causal relations between infections and development of islet autoimmunity are best assessed in longitudinal birth cohorts testing viral infections at frequent intervals before and during the development of islet autoimmunity. (diabetesjournals.org)
Herpangina5
  • Herpangina , an infection of the throat, causes red-ringed blisters and ulcers on the tonsils and soft palate, the fleshy back portion of the roof of the mouth. (kidshealth.org)
  • Children with coxsackievirus infections can have herpangina no relation to herpes infections), painful ulcers or sores on the roof of the mouth and tonsils. (healthychildren.org)
  • Further testing of the positive samples with other sequences and phylogenetic analysis showed that those positive for group A coxsackieviruses featured in 14/17 cases of herpangina, 8/11 febrile seizures, and 16/26 pharyngitis/tonsillitis. (bmj.com)
  • Grupo heterogéneo de infecciones producidas por coxsackievirus, que incluyen la HERPANGINA, la MENINGITIS ASÉPTICA, un síndrome similar al catarro común, un síndrome semejante a la poliomielitis no paralítica, la PLEURODINIA EPIDÉMICA y una MIOCARDITIS grave. (bvsalud.org)
  • A heterogeneous group of infections produced by coxsackieviruses, including HERPANGINA , aseptic meningitis (MENINGITIS, ASEPTIC), a common-cold-like syndrome, a non-paralytic poliomyelitis-like syndrome, epidemic pleurodynia (PLEURODYNIA, EPIDEMIC) and a serious MYOCARDITIS . (bvsalud.org)
Coxsackie virus3
  • Hand, foot and mouth disease is a viral infection caused by a strain of Coxsackie virus. (ny.gov)
  • Does a prior infection with Coxsackie virus make a person immune? (ny.gov)
  • Acute hemorrhagic edema of infancy associated with Coxsackie virus infection. (medscape.com)
Respiratory14
  • Coxsackieviruses can be spread through respiratory droplets that becomes airborne by sneezing and coughing. (healthychildren.org)
  • During August 2006-April 2010, in Beijing, China, 2 rare human enterovirus serotypes, coxsackievirus A21 and enterovirus 68, were detected most frequently in human enterovirus-positive adults with acute respiratory tract infections. (cdc.gov)
  • Clusters of the rare serotype enterovirus 68 (EV68), which causes severe respiratory infections in children, have been recently reported in the Philippines ( 4 ) and Japan ( 5 ). (cdc.gov)
  • To help clinicians and public health officials better understand the epidemiologic and clinical profiles of HEV respiratory infections, temporal and geographic patterns of circulation, especially the dynamics of HEV serotype shift, need to be determined. (cdc.gov)
  • We report that in some years in Beijing, People's Republic of China, the rarely reported coxsackievirus A21 (CVA21) and EV68 are the predominant serotypes in adults with enterovirus-associated acute respiratory tract infection (ARTI). (cdc.gov)
  • Common Cold The common cold is an acute, usually afebrile, self-limited viral infection causing upper respiratory symptoms, such as rhinorrhea, cough, and sore throat. (merckmanuals.com)
  • Infection is usually transmitted by direct contact with respiratory secretions or stool but can be transmitted by contaminated environmental sources (eg, water). (merckmanuals.com)
  • We documented EV D68 in open lung biopsies of a young adult patient who was frequently admitted to the hospital for severe exacerbation of respiratory infections and subsequently developed progressive respiratory insufficiency. (scirp.org)
  • The rash begins within 1 or 2 days of onset of the pharyngitis or other symptoms of an upper respiratory tract infection. (consultant360.com)
  • Symptoms of enterovirus infections include fever, headache, respiratory illness, and sore throat and sometimes mouth sores or a rash. (msdmanuals.com)
  • So, acute flaccid myelitis (or AFM for short) is an uncommon but serious neurologic condition that most often seems to occur after a viral upper respiratory infection. (cdc.gov)
  • We also know that more than 90% of children with AFM had an upper respiratory infection consistent with a viral infection in the days before they developed AFM symptoms. (cdc.gov)
  • Enterovirus 68 strains were detected in 14 specimens from children with respiratory tract infections and 1 specimen from a child with febrile convulsions during 2010 in Osaka, Japan. (blogspot.com)
  • EV68 was isolated from 4 children with pneumonia and bronchiolitis in the United States in 1962 (prototype Fermon strain) (2,3) and is associated with respiratory tract infections (RTIs) (3-5). (blogspot.com)
Serotypes3
  • This report describes the results of that analysis, which indicated that, in 2007, CVB1 for the first time was the predominant enterovirus in the United States, accounting for 113 (25%) of 444 enterovirus infections with known serotypes. (cdc.gov)
  • Co-circulation and co-infection of multiple serotypes were the etiological characteristic of the HFMD epidemic in Kunming China in 2019 with CV-A-6, CV-B1 and CV-A4 as the predominant serotypes. (biomedcentral.com)
  • Currently Coxsackieviruses (CV)-A6 and -A10 have become the predominant serotypes, causing mild, severe and fatal cases of HFMD [4]. (biomedcentral.com)
Conjunctivitis1
  • Hemorrhagic conjunctivitis , an infection that affects the whites of the eyes, usually begins as eye pain, followed quickly by red, watery eyes with swelling, light sensitivity, and blurred vision. (kidshealth.org)
Diagnosis5
  • A study from Japan has confirmed the potential of PCR and phylogenetic analysis to enable identification of group A coxsackieviruses and diagnosis of illnesses they cause in children. (bmj.com)
  • To protect a fetus from ToRCH infection, early diagnosis through first trimester screening is critical. (meridianbioscience.com)
  • Definitive diagnosis of a ToRCH infection, in particular HSV-1 or HSV-2, sometimes requires confirmation by IFA after a positive EIA result. (meridianbioscience.com)
  • They looked at type 1 diabetes incidence in children aged up to 18 years with or without diagnosis of EV infection during 2000-2008. (infectioncontroltoday.com)
  • Hazard ratios of type 1 diabetes increased with age at diagnosis of EV infection, with a more than doubling of the risk of type 1 diabetes (2.18 times increased risk) for children aged over 10 years at entry. (infectioncontroltoday.com)
Enteroviral infections4
  • The mechanism of IVIG in inhibiting enteroviral infections is unclear but thought to involve direct viral neutralization by specific antibodies along with downregulation of inflammatory cytokines. (medscape.com)
  • Both IVIG and pleconaril have been used in immunocompromised patients with severe enteroviral infections (neonates and B-cell immunodeficient) with varying success based mainly on case reports and and small case series (see Medical Care section). (medscape.com)
  • Enteroviral infections are most common among children. (msdmanuals.com)
  • Enteroviral infections usually resolve completely, but infections of the heart or central nervous system are occasionally fatal. (msdmanuals.com)
Symptoms12
  • infections cause mild flu-like symptoms and go away without treatment. (kidshealth.org)
  • What Are the Signs & Symptoms Coxsackievirus Infections? (kidshealth.org)
  • Coxsackievirus (kok-sak-ee-VY-rus) can cause a wide variety of symptoms. (kidshealth.org)
  • About half of all kids with an infection have no symptoms. (kidshealth.org)
  • A child with a coxsackievirus infection may simply feel hot but have no other symptoms. (kidshealth.org)
  • Depending on the type of infection and symptoms, the doctor may prescribe medicines to make your child feel more comfortable. (kidshealth.org)
  • If the fever lasts for more than 24 hours or if your child has any symptoms of a more serious coxsackievirus infection, call your doctor. (kidshealth.org)
  • The usual amount of time from exposure to the start of symptoms for most coxsackieviruses is 3 to 6 days. (healthychildren.org)
  • Your pediatrician will conduct a physical examination that evaluates signs and symptoms which may indicate a coxsackievirus infection. (healthychildren.org)
  • Treatment of enterovirus infections is aimed at relieving symptoms. (msdmanuals.com)
  • The body's immune defenses stop many enterovirus infections, and the result is few or no symptoms. (msdmanuals.com)
  • Treatment of enterovirus infections is directed at relieving symptoms. (msdmanuals.com)
Vaccine3
  • There is no vaccine to prevent coxsackievirus infection. (kidshealth.org)
  • The preclinical prototype vaccine is well-tolerated and provides strong protection against coxsackievirus B infections and diabetes in relevant animal models. (biotechnology.report)
  • Our results suggest that preventive strategies, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan. (infectioncontroltoday.com)
Influenza1
Inflammation3
  • Babies are more at risk for a serious infection, including myocarditis, hepatitis, and meningoencephalitis (an inflammation of the brain and meninges). (kidshealth.org)
  • Infections with coxsackievirus types B2 to B5 can cause swelling and inflammation of the heart's muscle and tissue layers, which is known as 'myopericarditis. (healthychildren.org)
  • We report that superoxide production following CB3 infection may exacerbate pancreatic b cell destruction in T1D by influencing proinflammatory M1 macrophage responses, and mechanistically linking oxidative stress, inflammation, and diabetogenic virus infections. (uab.edu)
Enterovirus 712
  • Using glucose-6-phosphate dehydrogenase (G6PD)-deficient fibroblasts as a model, this study demonstrated that the cellular redox status affects infectivity as well as the outcome of enterovirus 71 (EV71) infection. (microbiologyresearch.org)
  • Background: The hand-foot-mouth disease (HFMD) is an acute communicable disease, mostly affecting children under 5 years of age and caused by human enterovirus 71 (EV-A71) and coxsackievirus A16 (CV-A16). (who.int)
Fever5
  • Newborns that get enterovirus infections from their mothers at birth may have an overwhelming infection with fever that leads to liver failure, heart failure, meningitis, seizures , bleeding, and sometimes death. (healthychildren.org)
  • If an infection is causing the ulcers, your child might also have a fever. (xshotpix.com)
  • Some infections are associated with fever, which can cause chills or night sweats. (xshotpix.com)
  • 8 Thrush does not typically cause a fever, although some infants could have a coexisting viral infection that causes elevation in body temperature. (xshotpix.com)
  • Studies indicate that the type of infection - whether it's from a virus (first SARS pathogen in 2003, the Epstein-Barr virus (infectious mononucleosis , glandular fever), the Ross-River virus , the West Nile Virus, Ebola), or a bacteria ( Coxiella burnetii , Borrelia burgdorfii , Giardia lambia ) - it doesn't matter. (healthrising.org)
Meningitis2
  • Certain types of coxsackieviruses can cause meningitis (infection of the protective layers surrounding the brain and spinal cord). (healthychildren.org)
  • Coxsackievirus B3 (CVB3) has emerged as an active pathogen in myocarditis, aseptic meningitis, hand, foot, and mouth disease (HFMD), and pancreatitis, and is a heavy burden on public health. (researchsquare.com)
Treat infections caused1
  • There are no routine antiviral drugs used to treat infections caused by coxsackieviruses. (medscape.com)
Strains2
  • Innate recognition by neutrophil granulocytes differs between Neisseria gonorrhoeae strains causing local or disseminating infections. (medscape.com)
  • Enterovirus infections affect many parts of the body and may be caused by any of several different strains of enterovirus. (msdmanuals.com)
Antiviral drugs1
  • However, there are no vaccines or antiviral drugs available to treat CVB3 infections. (researchsquare.com)
Infants1
  • If there's an outbreak in a community, the risk for coxsackievirus infection is highest among infants and kids younger than 5. (kidshealth.org)
Contagious3
  • Are Coxsackievirus Infections Contagious? (kidshealth.org)
  • Coxsackieviruses are very contagious. (kidshealth.org)
  • Infections are highly contagious and typically affect many people in a community, sometimes reaching epidemic proportions. (msdmanuals.com)
Environmental triggers1
  • Coxsackievirus B infections are suspected environmental triggers of type 1 diabetes (T1D) and macrophage antiviral responses may provide a link to virus-induced T1D. (uab.edu)
CVB31
  • It has been previously demonstrated that dystrophin is cleaved in the cardiac myocyte by the viral protease 2A following infection with Coxsackievirus B3 (CVB3). (koreamed.org)
Myocardial1
  • Vitamin E deficiency intensifies the myocardial injury of coxsackievirus B3 infection of mice. (microbiologyresearch.org)
Severe2
  • Beginning in August 2007, CDC received multiple reports of cases of severe neonatal illness and death associated with enterovirus infection. (cdc.gov)
  • These may be signs of a severe infection. (xshotpix.com)
Oxidative stress1
  • Mechanistically, viral infection led to increased oxidative stress, as indicated by increased dichlorofluorescein fluorescence and a diminished ratio of glutathione (GSH) to its disulfide form (GSSG), with the effect being greater in G6PD-deficient cells. (microbiologyresearch.org)
Susi1
  • Österback R , Vuorinen T , Linna M , Susi P , Hyypiä T , Waris M . Coxsackievirus A6 and hand, foot, and mouth disease, Finland. (cdc.gov)
Bacteria2
  • Because antibiotics only work against bacteria, they can't be used to fight a coxsackievirus infection. (kidshealth.org)
  • X-linked Agammaglobulinemia X-linked agammaglobulinemia is characterized by low levels or absence of immunoglobulins and absence of B cells, leading to recurrent infections with encapsulated bacteria. (merckmanuals.com)
Diseases4
  • These infectious diseases are all associated with congenital abnormalities resulting from maternal infection. (meridianbioscience.com)
  • However, for some ToRCH diseases such as toxoplasmosis and CMV, IgG avidity has recently been found to be useful for identifying primary infections. (meridianbioscience.com)
  • Address reprint requests to Mailstop E-69, Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333. (cdc.gov)
  • and the Director, National Center for Infectious Diseases, regarding the practice of hospital infection control and strategies for surveillance, prevention, and control of nosocomial infections in US hospitals. (cdc.gov)
Mumps infection1
  • Viral orchitis is most often caused by mumps infection but can also be caused by a nonspecific inflammatory process in the testes. (medscape.com)
Herpes1
  • Herpes simplex virus (HSV) infection may be recurrent and may appear in a dermatomal distribution, mimicking herpes zoster and leading to misdiagnosis if no confirmatory laboratory tests are performed. (medscape.com)
HFMD3
  • Hand, foot and mouth disease (HFMD) is an extremely common infection seen in children, and is usually caused by coxsackievirus types A16 and A6. (healthychildren.org)
  • Hand-foot-mouth disease (HFMD) is most commonly caused by a virus called coxsackievirus A16. (medlineplus.gov)
  • Three hundred and forty-eight cases out of 459 HFMD patients were confirmed as EV infection. (biomedcentral.com)
Islet autoimmunity1
  • We've shown that enterovirus infection often precedes islet autoimmunity and the increased risk of type 1 diabetes , however direct evidence for a causal association between enterovirus infection and islet autoimmunity/type 1 diabetes is still missing. (edu.au)
Serious infections2
  • But in some cases, they can lead to more serious infections. (kidshealth.org)
  • More serious infections have been seen recently with a certain strain of Coxsackie viral infection in Indonesia. (ny.gov)
Neonatal2
  • Neonatal systemic enterovirus disease, characterized by multiorgan involvement, is among the most serious, potentially fatal conditions associated with enterovirus infection. (cdc.gov)
  • To describe the severity of neonatal illness associated with coxsackievirus B1 (CVB1) infection, CDC analyzed case reports and preliminary data from the National Enterovirus Surveillance System (NESS) for 2007. (cdc.gov)
Antibody2
  • An IgG antibody produced in the first few months following an initial infection has a lower avidity than an IgG antibody produced several months or years later. (meridianbioscience.com)
  • Consequently, low-avidity antibody can be used to specifically identify high-risk mothers with a primary infection. (meridianbioscience.com)
Signs1
  • You'll also be advised about diet, how to care for and treat the wounds and how to recognize possible signs of infection. (mymeditravel.com)
Characteristic1
  • The inhibition of calpains prevented the intracellular membrane modifications characteristic to enterovirus infection. (jyu.fi)
Group3
  • Group A coxsackieviruses are difficult to culture. (bmj.com)
  • Acute bacterial pharyngitis is most commonly due to a group A streptococcus (GAS) infection. (xshotpix.com)
  • ToRCH is an acronym for a group of infections that can cause significant birth defects and fetal death. (meridianbioscience.com)
Human1
  • In vitro studies have suggested that arbidol may have potential as a future antiviral agent with activity against coxsackievirus, but no human trials have been performed. (medscape.com)
Mice3
  • Upon infection with a suspected diabetogenic virus, Coxsackievirus B3 (CB3), NOD.Ncf1m1J mice remained resistant to virus-induced autoimmune diabetes. (uab.edu)
  • Coxsackievirus B3-resistant mice become susceptible in Se/vitamin E deficiency. (microbiologyresearch.org)
  • Benign coxsackievirus damages heart muscle in iron-loaded vitamin E-deficient mice. (microbiologyresearch.org)
Mild1
  • Although the organisms typically cause only asymptomatic or mild infection to the mother, they can have much more serious consequences to the fetus. (meridianbioscience.com)
Immune1
  • Poffenberger MC, Straka N , El Warry N, Fang D, Shanina I, Horwitz MS. Lack of IL-6 during coxsackievirus infection heightens the early immune response resulting in increased severity of chronic autoimmune myocarditis. (harvard.edu)
Diabetes4
  • Richer MJ, Straka N , Fang D, Shanina I, Horwitz MS. Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-beta. (harvard.edu)
  • To investigate the link between EV infection and subsequent type 1 diabetes, the researchers used nationwide population-based data from Taiwan's national health insurance system. (infectioncontroltoday.com)
  • The authors point out that despite countries such as Finland and Sweden having the highest incidence of type 1 diabetes worldwide, they are thought to have low background rates of enterovirus infection, suggesting that genetic factors are a large component of the high type 1 diabetes rates in those countries. (infectioncontroltoday.com)
  • They conclude: 'This nationwide retrospective cohort study found a positive correlation of type 1 diabetes with EV infection. (infectioncontroltoday.com)
Newborns1
  • Mothers can pass an infection to their newborns during or just after birth. (kidshealth.org)
Rash1
  • If the doctor suspects that your child has hand, foot and mouth disease, your pediatrician will look for the rash associated with this infection as well as for sores in the mouth and throat. (healthychildren.org)
Throat2
  • Hand-foot-mouth disease is a common viral infection that most often begins in the throat. (medlineplus.gov)
  • Common Cold The common cold is a viral infection of the lining of the nose, sinuses, and throat. (msdmanuals.com)