Compounds containing the PhCH= radical.
A piperidine botanical insecticide.
A plant genus of the family POACEAE that is grown mainly as a hay crop.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
An aminobenzoic acid isomer that combines with pteridine and GLUTAMIC ACID to form FOLIC ACID. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in SUNSCREENS.
A dipolar ionic buffer.
Aminobenzoate derivatives that contain an amino group attached to carbon number 3 or 5 of the benzene ring structure.
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Benzoic acids, salts, or esters that contain an amino group attached to carbon number 2 or 6 of the benzene ring structure.
Derivatives of BENZOIC ACID that contain one or more amino groups attached to the benzene ring structure. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the aminobenzoate structure.
Inorganic compounds that contain fluorine as an integral part of the molecule.
The effect of GLOBAL WARMING and the resulting increase in world temperatures. The predicted health effects of such long-term climatic change include increased incidence of respiratory, water-borne, and vector-borne diseases.
Hydrocarbons with at least one triple bond in the linear portion, of the general formula Cn-H2n-2.
An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Inorganic or organic oxy acids of sulfur which contain the RSO2(OH) radical.
The study of the structure, preparation, properties, and reactions of carbon compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Methods used for the chemical synthesis of compounds. Included under this heading are laboratory methods used to synthesize a variety of chemicals and drugs.
A reagent that is used to neutralize peptide terminal amino groups.
Amide derivatives of phosphoric acid such as compounds that include the phosphoric triamide (P(=O)(N)(N)(N)) structure.
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
The reactions, changes in structure and composition, the properties of the reactions of carbon compounds, and the associated energy changes.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Neutral or negatively charged ligands bonded to metal cations or neutral atoms. The number of ligand atoms to which the metal center is directly bonded is the metal cation's coordination number, and this number is always greater than the regular valence or oxidation number of the metal. A coordination complex can be negative, neutral, or positively charged.
A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.
Compounds possessing both a hydroxyl (-OH) and an amino group (-NH2).
Oligosaccharides containing three monosaccharide units linked by glycosidic bonds.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
The misinterpretation of a real external, sensory experience.
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.
A mechanistic study by Plenio and coworkers in 2012 suggested that the Zhan compounds, like other Hoveyda-type catalysts, ... As with other Grubbs-type catalysts with modified chelating benzylidenes, after one catalytic turnover, the chelate is no ... In 2015, Engle, Houk, Grubbs, and coworkers developed a model that could rationalize initiation rates of ruthenium olefin ... "Origins of Initiation Rate Differences in Ruthenium Olefin Metathesis Catalysts Containing Chelating Benzylidenes". J. Am. Chem ...
Seto and coworkers named these compounds Aspulvinones. The aspulvinone terminology also incorporates a letter, indicating the ... Ewan achieved the synthesis of this side-product and characterized it as the 5-benzylidene-4-hydroxy-3-phenylfuran-2(5H)-one. ... Pulvinone, an organic compound belonging to the esters, lactones, alcohols and butenolides classes, is a yellow crystalline ... Yet vulpinic acid - as well as many of its derivatives - is a cytotoxic compound. Since pulvinones exhibit a lower cytotoxicity ...
Treatment of these compounds with TBAF invokes a ring-expansion that provides the corresponding benzazepines. One variation of ... In 2013, Doyle and coworkers reported a Povarov-type, formal [4+2]-cycloaddition reaction between donor-acceptor cyclopropenes ... 10.1016/j.tet.2008.12.059 Unprecedented regio and stereocontrol in Povarov reaction of benzylidene-(3-nitrophenyl)amine Paul J ... The imine in this organic reaction is a condensation reaction product from an aniline type compound and a benzaldehyde type ...
... anabaseine compounds containing a benzylidene substitution at the 3′ position; ANOVA, analysis of variance; GR65630, 3-(5- ... Papke and co-workers have demonstrated that DMXBA and its metabolites differ in partial agonist potency and efficacy in rat, ... No partial agonism was observed with any of these compounds (Fig. 2A). Antagonistic actions of the BA compounds (0.25-50 μM) ... none of the BA compounds possessed partial agonist activity. BA compounds antagonized 1.5 μM 5-HT-mediated (EC50) responses in ...
... compound 20 in patent WO2013/119946A1) (Fig. 2), while the compounds containing 1,3,4-oxadiazoles (compound 30 in patent WO2013 ... SKI-I, SKI-II, SKI-III and SKI-IV were identified by a high throughput screen by Smith and co-workers in 2003 (Fig. 3). They ... containing two benzenesulfonamide groups joined by a benzylidene-aniline group. To assess the selectivity, MP-A08 was tested ... compound 11, compound 20 and compound 30; bicyclic aryl based derivatives include SLC5091592, SLC5081308 and SLC5111312; amino- ...
A mechanistic study by Plenio and coworkers in 2012 suggested that the Zhan compounds, like other Hoveyda-type catalysts, ... As with other Grubbs-type catalysts with modified chelating benzylidenes, after one catalytic turnover, the chelate is no ... In 2015, Engle, Houk, Grubbs, and coworkers developed a model that could rationalize initiation rates of ruthenium olefin ... "Origins of Initiation Rate Differences in Ruthenium Olefin Metathesis Catalysts Containing Chelating Benzylidenes". J. Am. Chem ...
1).2 This reaction has been shown to proceed successfully with a range of NH-, OH- and CH-acidic compounds.2 However, CHF2Cl is ... Instead, the N-benzylidene- and the O-methyl-protecting groups were directly removed by heating the crude product in 6 N HCl in ... For an alternative mechanistic hypothesis suggested by Mikami and co-workers, see ref. 5. ... Isolated yields after 2 steps (Cα-difluoromethylation and hydrolysis of the N-benzylidene- and the O-methyl-protecting groups ...
Seto and coworkers named these compounds Aspulvinones. The aspulvinone terminology also incorporates a letter, indicating the ... Ewan achieved the synthesis of this side-product and characterized it as the 5-benzylidene-4-hydroxy-3-phenylfuran-2(5H)-one. ... Pulvinone, an organic compound belonging to the esters, lactones, alcohols and butenolides classes, is a yellow crystalline ... Yet vulpinic acid - as well as many of its derivatives - is a cytotoxic compound. Since pulvinones exhibit a lower cytotoxicity ...
I have tried to present the experimental work carried out by m-v co-workers cited in the references and which was discussed in ... furfural 2-acetylfuran 2-acetylthiophene 2-acetyl-1-methylpyrrole cinnamaldehyde benzylidene acetone An,qor. 10 0 4 with ... unsaturated cdrbonyl compound [23]. Conditions as In Table 1 : recovery of unconverted carbonyl compound: 0-14%. ... Compound 64, prepared by Hashimoto et 2 1 1 . ~ ~(THF, ~ 6 h, 40°C) and by Fried et al.771(Et,0, 4 h, 78°C) by rcaction of CH ...
... azobenzene derivatives and above photochromic compounds are just examples of a whole family of compounds capable of performing ... M. Blanco-Lomas, P. J. Campos, and D. Sampedro, "Benzylidene-oxazolones as molecular photoswitches," Organic Letters, vol. 14, ... are obtained from the density-functional-based parameterizations of Frauenheim and coworkers [33, 34]. ... trans photoisomerizations of a green fluorescent protein chromophore based molecule 4-benzylidene-2-methyloxazol-5(4H)-one (BMH ...
Examples of chiral compounds complete the spectrum of NHC ruthenium complexes. Synthetic methods, catalytic properties and ... Of these chiral ruthenium benzylidene complexes, compound 47 showed a wide range of metathesis activity and a particularly high ... Taking advantage of these properties, Blechert and coworkers (34) prepared immobilised ruthenium complexes via imidazolin-2- ... In addition to the chiral ruthenium complexes (R,R)-10 and (R,R)-11 described above (11), new chiral NHC ruthenium benzylidene ...
Co-workers:. Friedemann Dreßler, Frederik R. Erb, Christian Eschmann, Kai Feuer, Alexander Seitz, Christopher Topp, Dr. Raffael ... compounds such as phthalides and isoindolinones. Here, we use (+)-cinchonine as a catalyst in conjunction with nonafluoro-tert- ... As a proof of principle, we employed (4,6-O-benzylidene)methyl-α-d-pyranosides, which provide a change in regioselectivity from ... We describe an organocatalytic iodination of activated aromatic compounds using 1,3-diiodo-5,5-dimethylhydantoin (DIH) as the ...
... and two model compounds, LnL3 and LnL4. All of the Gd3+ complexes synthesized have a single inner-sphere water molecule. The ... Key steps include the oxidative cleavage of a 4,6-O-benzylidene acetal to prepare a disaccharidic glycosyl acceptor, and ... The results of the methodology were compared with those of the procedure of Yoneyama and coworkers. Results This procedure ... These new compounds possess a common dimethylbutenolide motif but their structure varies in the ABC part of the molecules: 23 ...
36 20212 p mu0 D mu1 C MV 5. Methyl 4,7-O -benzylidene. Dollar AL, especially in younger men, was one of the initial goals ... In amperometric mode compounds undergo oxidation or reduction reaction through the loss or gain, respectively. 4 lb Water ... based temporally resolved pump-probe X-ray diffraction experiment was subsequently performed by Coppens and coworkers on a ... Integrated bridge systems 207 Peak energy Compound identification Band gapelectronic levels Impurity or exciton binding energy ...
Picture made out of the cartoon choice in PyMOL.[48] Recently, Ohori and co-workers identified further inhibitors from the ERK2 ... Ohori conducted a high-throughput phosphorylation assay with an in-house chemical substance library to recognize compounds with ... Researchers in GlaxoSmithKline synthesized and screened some more than 2000 benzylidene oxindole substances inside a Raf1/MEK/ ... Furthermore to employing the crystal structure of inactive (non-phosphorylated) ERK, Shapiro, MacKerell and co-workers also ...
Attachment of Compound A to Styrene/Maleic Anhydride Copolymer with Compound E. Into the 200° C. mixing chamber of a Brabender ... benzylidene malonate esters, esters of substituted or unsubstituted benzoic acids, diphenyl acrylates, nickel chelates, oxalic ... modification of EPDM by maleic anhydride in the presence of dicumyl peroxide and benzoyl peroxide is described by DeVito and co-workers ... Accelerated Weathering of HIPS Stabilized with Compound A Attached to SMA™ 1000. A. Preparation of Compound A/SMA 1000 ...
... benzylidene-bis(tricyclohexylphosphine)dichlororuthenium; Grubbs II = benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2- ... In addition, 94 compounds have been submitted for broad screening in the National Institutes of Health (NIH) Molecular ... Similarly, Saito and coworkers Ni(0)-catalyzed [3 + 2 + 2] cycloaddition with ethyl cyclopropylidene acetate (31) was ... BINAP complex catalyzed [2 + 2 + 2] cycloadditions of 1,6- and 1,7-diynes with carbonyl compounds. Eur J Org Chem, 2737-2747. ...
Ballini and co-workers also examined the reaction of the Michael adduct 98 with Grignard reagents. The use of anhydrous cerium( ... intermediate, generates a-benzylidene-g-butyrolactone 210 in moderate yield as an 8:1 mixture with 3-benzylfuran-2-(5H)one 211 ... Such compounds can cause allergenic contact dermatitis (ACD)[42] and photodermatosis.[43] It has been proposed that the a- ... Adam and co-workers developed an effective method for the preparation of optically active a-alkylidene-g-butyrolactones by a ...
In some embodiments, the compounds modulate RecA activity by interfering with assembly of monomeric RecA protein subunits into ... In some embodiments, the compounds modulate RecA activity by interfering with adenosine triphosphate hydrolysis by the RecA ... Methods of screening for and methods of using the compounds are also provided. ... Compounds for modulating RecA protein activity are provided. ... protein selection have been developed by Liu and coworkers (Cho ...
Farahi and co-workers successfully reported a novel magnetically heterogeneous catalyst by promotion of boron sulfonic acid ... 50] Hamadi, H., & Javadi, S. (2017). One-pot Reductive Amination of Carbonyl Compounds with NaBH 4-B (OSO 3 H) 3/SiO 2 in ... Some of biscoumarins derivatives are successful urease and HIV inhibitors [44, 45]. Typically, α,α-benzylidene bis(4- ... Over the last few years, the great potential of solid acid catalysts has been attracted in the synthesis of organic compounds. ...
GM food plants have been extensively analyzed for the presence of toxic compounds and have been approved by the Food and Drug ... de Groot and coworkers 1-3 and are summarized briefly in Table 3. It has clearly been shown that certain categories of ... high incidence of adverse photosensitivity reported with the combination of isopropyldibenzoylmethane and methyl-benzylidene ... Ginseng saponins are structurally near chemical relatives of the antiinflammatory compounds such as steroids and glycyrrhetinic ...
When ATP-dependent uptake was decreased a lot more than 66.7%, the compound was considered a potential inhibitor, and multiple. ... 2-benzylidene malonic acidity 18: produce: 55%. 1H NMR (400 MHz, DMSO) 7.63 C 7.55 (m, 2H), 7.54 (s, 1H), 7.48 C 7.42 (m, 3H). ... Faul and co-workers have shown inside a mouse model that FGF23 software leads to myocardial hypertrophy [9], a discovering that ... benzylidene)malonate 11: produce: 63%. 1H NMR (300 MHz, CDCl3) 7.69 (s, 1H), 7.35 (dd, = 9.1, 0.4 Hz, 2H), 6.65 (d, = 9.0 Hz, ...
... first reported by Wittig and co-workers;9 and type 3, an alkyl exchange reaction between an alkyl zinc and a 1,1-dihaloalkane, ... such as benzylidene and ethylidene iodide, also gives rise to active cyclopropanating reagents.13 Recently, the substitution of ... 2 transmetalation with various metal halides affords other iodomethylmetal compounds3) Alternate Name: Simmons-Smith reagent. ... and heteroarylcopper compounds all participate in this reaction (eq 16). This reaction has proven to be especially useful for ...
41A: COMPOUND 41A, 41B: COMPOUND 41B. Rani et al 22 synthesized pyrazoline derivatives and evaluated them for their anti- ... Bhat and co-workers reported bis-pyrazolines 34 prepared by cyclization of chalcones with N-4 substituted thiosemicarbazides ... and in an inert atmosphere to give 4-benzylidine derivatives. Pyrazoline derivatives, typical ICT (Intramolecular Charge ... Out of 93 compounds screened, 8 compounds showed marked activity 64. Manna et al., synthesized a series of substituted ...
1 is a proton NMR spectrum of the Bis-methyl ester of compound P-33. [0047] FIG. 2 is a proton NMR spectrum of the compound P- ... 0018] Alternatively RL and RS can combine to form a benzylidene or substituted benzylidene ring. [0019] In a second aspect the ... Research conducted by Lindahl and co-workers and separately by Choay and co-workers2 eventually led to the determination that ... Process for preparation of ketolide compounds. Top Inventors for class "Organic compounds -- part of the class 532-570 series" ...
Stambuli and co-workers reported similar a yield to Kobayashi and co-workers for the Yb(OTf)3 catalysed formation of the THIQ ... N-benzylidene-2-phenylethanamine (1a). To a stirring solution of benzaldehyde (4 mL, 40 mmol, 1 equiv.) in diethyl ether (10 mL ... 31] Evaluation of the relative Lewis acidities of lanthanoid(III) compounds by tandem mass spectrometry, H. Tsuruta, K. ... Scheme 7: The conditions for the Pictet-Spengler reaction of m-tyramine and benzaldehyde reported by Kobayashi and co-workers.[ ...
Benzylidene acetone. (4-phenyl-3-buten-2-one). 122-57-6. -1,81. 2.45. 146.19. AOO. 10.0. 25.0. 50.0. -. -. -. 8.5. 13.6. 12.8. ... The investigations described by Ryan and coworkers (Ryan, 2000) were designed to explore further the ability of the LLNA to ... as well as compounds that have different reactivity mechanisms. In addition, the physicochemical parameters log Kp, log Ko/w ... Benzylidene acetone. 1%. Ethanol (70°). 66-6. 1-81. 3/6 showed lesions of allergic type with intense spongiosis, exocytosis and ...
In 1981 in JAMA, Moertal and co-workers wrote: "In our study, intravenous amygdalin was found to be free of clinical toxicity ... has defined them as "...water soluble, essentially non-toxic, sugary compounds found in... plants, many of which are edible ... 34) litsumlira, T. et al -(1990) "4,6-0-Benzylidene-D-glucopyranose (BG) in the treatment of solid malignant ibbiois, an ... Robert Atkins, M.D., notes that "Amygdalin appears to neutralize the oxidative cancer-promoting compounds such as free radicals ...
... ruthenium allenylidene complexes allow synthesis of a wide range of heterocyclic and carbocyclic compounds through ring-closing ... The latter compound reacts rapidly with the suitably substituted propyn-3-ol (in CH2Cl2 at room temperature) to give the ... 15 was synthesised almost simultaneously by Fürstner and Hill (38), and Nolan and coworkers (39) by reacting [RuCl2(PPh3)3] or ... 17, is a highly active metathesis ruthenium complex, and is related to the binuclear benzylidene complex [Ru2Cl4(=CHPh)(p- ...
Kirby and coworkers [3-8] reported the formation of ethyl thioxoacetate (3) from sulphonyl chloride (2) by elimination of ... The compound chosen was the dienamine (19) prepared [12] from the readily accessible enone, Pummerers ketone (18). Scheme 4. ... Y. Watanabe and T. Skakibara, "Synthesis of methyl 4,6-O-benzylidene-2,3-dideoxy-5-thio-β-dl-threo-hex-2-enopyranoside via ... The compounds with sulphur attached to C (1) of the diene were found to be formed predominantly. This regiochemistry ...
88. The compound of claim 85, wherein P is methyl. 89.-102. (canceled) 103. The compound of claim 85, wherein the compound is ... In 1962, Woodward and co-workers reported the first total synthesis of racemic 6-desmethyl-6-deoxytetracycline (sancycline, 4 ... benzylidene derivative, 2-oxacyclopentylidene ortho ester, di-t-butylsilylene group (DTBS), 1,3-(1,1,3,3- ... 106. The compound of claim 84, wherein P is methyl. 107. The compound of claim 84, wherein P is benzyl. 108. The compound of ...
Uenishi and coworkers have since applied these oxypalladation cyclizations to the construction of several intricate comp ounds ... Z ) 2 ben zylidene 6 vinyl 1,4 dioxane (3 93d ) : A test tube with septum containing a stir bar, triphenylphosphine gold(I) c ... 48 due to their prevalence in natural pr oducts and biologically relevant compounds. In 2008, Aponick and coworkers reported ... 27 Hirai and coworkers were the firs t to exhibit the effectiveness of a palladium(II) catalyzed formal S N heterocyclization ...
Tan, J. and Kok, J.L. and Tan, K.L. and Wee, Y.C. and George, E. (2009) Thalassemia intermedia in HbH-CS disease with compound ... Lair, N.M. and Ng, Seik Weng and Ali, Hapipah Mohd (2009) Bis 4-hydroxy-N -(4-methoxy-2-oxido-benzylidene-kappa O-2) ... Lin Dar, O. (2009) Trust in coworkers and employee behaviors at work. In: 11th International Business Research Conference, 2-4 ... Journal of Alloys and Compounds, 486 (1-2). pp. 645-648. ISSN 0925-8388 ...
  • In 2015, Engle, Houk, Grubbs, and coworkers developed a model that could rationalize initiation rates of ruthenium olefin metathesis catalysts with chelated benzylidenes, using a combination of organometallic synthesis, reaction kinetics, NMR spectroscopy, X-ray crystallography, and DFT calculations. (wikipedia.org)
  • Ewan achieved the synthesis of this side-product and characterized it as the 5-benzylidene-4-hydroxy-3-phenylfuran-2(5H)-one. (wikipedia.org)
  • 11 ) published the synthesis of an array of NHC ruthenium complexes, for example, 7-10 , by substitution reactions of the diphosphane ruthenium benzylidene complex 2 with imidazolin-2-ylidene groups. (matthey.com)
  • A major goal in the field of diversity-oriented synthesis is the efficient production of small-molecule libraries that address underexploited regions of biologically relevant chemical space to enable the discovery of new biological probes and potential therapeutic lead compounds ( 1 ). (pnas.org)
  • The main purpose of the current Review is to collate and outline the various synthetic methods used for the synthesis of these compounds, with particular emphasis on the period 1986- 2008. (docme.ru)
  • His research interests focus on the application of new reagents in organic reactions, the synthesis of different types of organic compounds, design, and study of novel solid acid catalyst and organic reaction. (jchemrev.com)
  • Her research interests are in the area of the synthesis of organic compounds particularly heterocycles and synthetic methodology. (jchemrev.com)
  • Over the last few years, the great potential of solid acid catalysts has been attracted in the synthesis of organic compounds. (jchemrev.com)
  • Some compounds had been synthesized by the microwave method of synthesis, which is more convenient than the normal method of synthesis. (ijpsr.com)
  • By virtue of these beneficial features, ruthenium allenylidene complexes allow synthesis of a wide range of heterocyclic and carbocyclic compounds through ring-closing metathesis (RCM) and enyne metathesis as well as production of specialty polymers by acyclic diene metathesis (ADMET) and ring-opening metathesis polymerisation (ROMP). (matthey.com)
  • Examples of chiral compounds complete the spectrum of NHC ruthenium complexes. (matthey.com)
  • Recent papers in this series ( 1 ) illustrated that, besides the highly active and stereoselective tungsten and molybdenum imido alkylidene metathesis catalysts, extensively developed by Schrock and coworkers ( 2 , 3 ), a large class of ruthenium complexes have been successfully applied in organic and polymer syntheses ( 4-9 ). (matthey.com)
  • Also, several chiral imidazolin-2-ylidene ruthenium complexes have been prepared by the above approach, such as ( R , R )- 10 and ( R , R )- 11 (Ar = Ph or Naph), via reaction of diphosphane ruthenium benzylidene complex 2 (R = Ph or Cy) with selected chiral imidazolin-2-ylidene ligands ( 11b ). (matthey.com)
  • 17 , is a highly active metathesis ruthenium complex, and is related to the binuclear benzylidene complex [Ru 2 Cl 4 (=CHPh)( p -cymene)(PCy 3 )] reported earlier by Grubbs and coworkers ( 40 ). (matthey.com)
  • As with other Grubbs-type catalysts with modified chelating benzylidenes, after one catalytic turnover, the chelate is no longer associated with the propagating catalyst, meaning that the initiate rate, the rate of o-alkoxystyrene rechelation, and the rates of various catalyst decomposition events are the factors that differ between the Zhan catalysts and the parent Hoveyda-Grubbs catalysts. (wikipedia.org)
  • A mechanistic study by Plenio and coworkers in 2012 suggested that the Zhan compounds, like other Hoveyda-type catalysts, initiate by competing dissociative and interchange mechanisms, with the relative activation energies being a function of catalyst structure, olefin identity, and reaction conditions. (wikipedia.org)
  • Despite their appealing features as effective molecular switches, azobenzene derivatives and above photochromic compounds are just examples of a whole family of compounds capable of performing controlled isomerization reactions. (hindawi.com)
  • 6] the hispitolides (e.g. hispitolide A, 3), a newly discovered family of compounds Angew. (docme.ru)
  • Pyrazoline is a five-membered heterocyclic compound having two adjacent nitrogen atoms within the ring. (ijpsr.com)
  • Pyrazole Fig. 1 refers to the class of simple aromatic ring organic compounds of the heterocyclic series characterized by a 5-membered ring structure composed of three carbon atoms and two nitrogen atoms in adjacent positions. (ijpsr.com)
  • Pulvinone, an organic compound belonging to the esters, lactones, alcohols and butenolides classes, is a yellow crystalline solid. (wikipedia.org)
  • Inorganic compound continues to be important in therapy, for example, as antacids, mineral supplements, and radiopharmaceuticals, but organic molecules with increasingly specific pharma-cological activities are clearly dominant. (ijpsr.com)
  • The aspulvinone terminology also incorporates a letter, indicating the order of chromatographic elution of these compounds (hence, the least polar aspulvinone was named Aspulvinone A, the one eluting next Aspulvinone B, etc. (wikipedia.org)
  • They have characterized the synthesized compounds by thin-layer chromatographic technique and analyzed the spectrum by IR, NMR, Mass spectra. (ijpsr.com)
  • Yet vulpinic acid - as well as many of its derivatives - is a cytotoxic compound. (wikipedia.org)
  • Novel Reactions of Organomolybdenum and Organotungsten Compounds AdditiveЦReductive Carbonyl Dimerization Spontaneous Transformation of Methyl Ligands into -Methylene Ligands and Selective Carbonylmethylenation. (docme.ru)
  • REVINS Novel Reactions of Organomolybdenum and Organotungsten Compounds: Additive -Reductive Carbonyl Dimerization, Spontaneous Transformation of Methyl Ligands into p-Methylene Ligands, and Selective Carbonylmethylenation'* Thomas Kauffmann' Hitherto there was no reaction known that permits transformations of R'R2CO + 0.5 R1RZR3C-CR1RZR3in one step. (docme.ru)
  • 2 This reaction has been shown to proceed successfully with a range of NH-, OH- and CH-acidic compounds. (rsc.org)
  • To furnish a deeper and detailed mechanistic understanding of the photoisomerization reaction of those green fluorescent protein chromophore based molecular switches, semiclassical nonadiabatic molecular dynamics simulations were performed for a molecule 4-benzylidene-2-methyloxazol-5(4H)-one (BMH, named as 2e in [ 27 ]) in our group. (hindawi.com)
  • In amperometric mode compounds undergo oxidation or reduction reaction through the loss or gain, respectively. (fuantrading.com)
  • In 1831, in the course of a study of the constituents of lichens (Cetraria Vulpina), the French chemist and pharmacist Antoine Bebert discovered a compound named vulpinic acid, the first known naturally occurring methyl ester of pulvinic acid. (wikipedia.org)
  • The benzylidene anabaseine analogs have also been useful as molecular probes of the ligand binding domains of the α7 nicotinic receptor and 5-HT 3A receptor. (aspetjournals.org)
  • It is concerned with the invention, discovery, design, identification of biologically active compounds, the study of their pharmacokinetic and pharmacodynamic profiles, interpretation of their mode of action at the molecular level and the construction of structure-activity relationship (SAR), the relationship between chemical structure and pharmacological activity for a series of compounds. (ijpsr.com)
  • This Review summarizes the structural types, biological activities, and biosynthesis of these compounds, concentrating on publications from the past 10 years. (docme.ru)
  • The present study tested the hypothesis that mouse and human 5-hydroxytryptamine 3A (5-HT 3A ) receptors may be differentially modulated by benzylidene analogs of anabaseine (BA) and that these analogs may be useful in assessing residues involved in receptor gating. (aspetjournals.org)
  • In the human wild-type (HWT) 5-HT 3A receptor, none of the BA compounds possessed partial agonist activity. (aspetjournals.org)
  • Compounds for modulating RecA protein activity are provided. (justia.com)
  • In some embodiments, the compounds modulate RecA activity by interfering with assembly of monomeric RecA protein subunits into a nucleoprotein filament. (justia.com)
  • In some embodiments, the compounds modulate RecA activity by interfering with adenosine triphosphate hydrolysis by the RecA protein. (justia.com)
  • The currently disclosed subject matter relates to methods and compounds for modulating RecA protein activity. (justia.com)
  • Methods of screening for and methods of using the compounds are also provided. (justia.com)
  • The objective of medicinal chemistry is the design and production of compounds that can be used as medicine for the prevention, treatment, and cure of humans or animal diseases. (ijpsr.com)
  • In the very same year 1973, Seto and coworkers also found hydroxylated pulvinones in cultures of the mould Aspergillus terreus. (wikipedia.org)
  • To insist on their origin - and thereby differentiate them from the hydroxylated pulvinones found in Suillus grevillei - Seto and coworkers named these compounds Aspulvinones. (wikipedia.org)
  • water soluble, essentially non-toxic, sugary compounds found in. (encognitive.com)
  • 6b Treatment of Et 2 Zn with substituted diiodides, such as benzylidene and ethylidene iodide, also gives rise to active cyclopropanating reagents. (paperplane.io)