A organothiophosphorus cholinesterase inhibitor that is used as an anthelmintic, insecticide, and as a nematocide.
A pesticide or chemical agent that kills mites and ticks. This is a large class that includes carbamates, formamides, organochlorines, organophosphates, etc, that act as antibiotics or growth regulators.
A sweet viscous liquid food, produced in the honey sacs of various bees from nectar collected from flowers. The nectar is ripened into honey by inversion of its sucrose sugar into fructose and glucose. It is somewhat acidic and has mild antiseptic properties, being sometimes used in the treatment of burns and lacerations.
Diseases in persons engaged in cultivating and tilling soil, growing plants, harvesting crops, raising livestock, or otherwise engaged in husbandry and farming. The diseases are not restricted to farmers in the sense of those who perform conventional farm chores: the heading applies also to those engaged in the individual activities named above, as in those only gathering harvest or in those only dusting crops.
Insect members of the superfamily Apoidea, found almost everywhere, particularly on flowers. About 3500 species occur in North America. They differ from most WASPS in that their young are fed honey and pollen rather than animal food.
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.
Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.

Identification of an opd (organophosphate degradation) gene in an Agrobacterium isolate. (1/12)

We isolated a bacterial strain, Agrobacterium radiobacter P230, which can hydrolyze a wide range of organophosphate (OP) insecticides. A gene encoding a protein involved in OP hydrolysis was cloned from A. radiobacter P230 and sequenced. This gene (called opdA) had sequence similarity to opd, a gene previously shown to encode an OP-hydrolyzing enzyme in Flavobacterium sp. strain ATCC 27551 and Brevundimonas diminuta MG. Insertional mutation of the opdA gene produced a strain lacking the ability to hydrolyze OPs, suggesting that this is the only gene encoding an OP-hydrolyzing enzyme in A. radiobacter P230. The OPH and OpdA proteins, encoded by opd and opdA, respectively, were overexpressed and purified as maltose-binding proteins, and the maltose-binding protein moiety was cleaved and removed. Neither protein was able to hydrolyze the aliphatic OP malathion. The kinetics of the two proteins for diethyl OPs were comparable. For dimethyl OPs, OpdA had a higher k(cat) than OPH. It was also capable of hydrolyzing the dimethyl OPs phosmet and fenthion, which were not hydrolyzed at detectable levels by OPH.  (+info)

Cloning and expression of the phosphotriesterase gene hocA from Pseudomonas monteilii C11. (2/12)

The cloning of a gene encoding the novel phosphotriesterase from Pseudomonas monteilii C11, which enabled it to use the organophosphate (OP) coroxon as its sole phosphorus source, is described. The gene, called hocA (hydrolysis of coroxon) consists of 501 bp and encodes a protein of 19 kDa. This protein had no sequence similarity to any proteins in the SWISS-PROT/GenBank databases. When a spectinomycin-resistance cassette was placed in this gene, phosphotriesterase activity was abolished and P. monteilii C11 could no longer grow with coroxon as the sole phosphorus source. Overexpression and purification of HocA as a maltose-binding protein fusion produced a protein having a broad substrate specificity across oxon and thion OPs. Michaelis-Menten kinetics were observed with the oxon OPs, but not with the thion OPs. End-product inhibition was observed for coroxon-hydrolytic activity. Increased expression of hocA was observed from an integrative hocA-lacZ fusion when cultures were grown in the absence of phosphate, suggesting that it might be part of the Pho regulon, but the phosphate-regulated promoter was not cloned in this study. This is believed to be the first study in which a gene required for an organism to grow with OP pesticides as a phosphorus source has been isolated.  (+info)

Transient expression of organophosphorus hydrolase to enhance the degrading activity of tomato fruit on coumaphos. (3/12)

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Coumaphos exposure and incident cancer among male participants in the Agricultural Health Study (AHS). (4/12)

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Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer. (5/12)

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CYP9Q-mediated detoxification of acaricides in the honey bee (Apis mellifera). (6/12)

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Acute exposure to a sublethal dose of imidacloprid and coumaphos enhances olfactory learning and memory in the honeybee Apis mellifera. (7/12)

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Exposure to multiple cholinergic pesticides impairs olfactory learning and memory in honeybees. (8/12)

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1. Pesticide poisoning: Agricultural workers who handle or apply pesticides may be at risk for poisoning, which can cause a range of symptoms including headaches, dizziness, and nausea. Prolonged exposure to pesticides has also been linked to an increased risk of cancer.
2. Lung disease: Agricultural workers who work with dusty crops or in confined spaces may be at risk for lung diseases such as bronchitis, emphysema, and asthma.
3. Heat stress: Agricultural workers who work outdoors during hot weather may be at risk for heat stress, which can lead to symptoms such as dizziness, nausea, and fatigue. In severe cases, heat stress can be fatal.
4. Noise-induced hearing loss: Agricultural workers who are exposed to loud noises, such as tractors or other machinery, may be at risk for noise-induced hearing loss.
5. Musculoskeletal disorders: Agricultural workers may be at risk for musculoskeletal disorders such as back pain, joint pain, and repetitive strain injuries due to the physical demands of their work.
6. Skin diseases: Agricultural workers who handle animals or are exposed to chemicals may be at risk for skin diseases such as allergic contact dermatitis or fungal infections.
7. Eye diseases: Agricultural workers who work with pesticides or other chemicals may be at risk for eye diseases such as conjunctivitis or cataracts.
8. Respiratory diseases: Agricultural workers who handle grain or other dusty materials may be at risk for respiratory diseases such as hypersensitivity pneumonitis or farmer's lung.
9. Infectious diseases: Agricultural workers may be at risk for infectious diseases such as Q fever, which is caused by a bacteria that can be found in the intestines of some animals.
10. Mental health disorders: The stress and isolation of agricultural work may contribute to mental health disorders such as depression, anxiety, or substance abuse.

It's important for agricultural workers to take precautions to protect their health and safety on the job, such as wearing personal protective equipment, following proper handling and application procedures for chemicals, and taking regular breaks to rest and stretch. Additionally, employers should provide a safe work environment and training on safe work practices to help prevent injuries and illnesses.

... is a nonvolatile, fat-soluble phosphorothioate with ectoparasiticide properties: it kills insects and mites. It is ... cite journal}}: Cite journal requires ,journal= (help) Coumaphos, US Environmental Protection Agency v t e (CS1 errors: missing ... www.apvma.gov.au https://web.archive.org/web/20080829185148/http://www.apvma.gov.au/chemrev/coumaphos.shtml. Archived from the ...
coumaphos Archived February 5, 2005, at the Wayback Machine "Demeton-S-methyl". Extoxnet. Retrieved July 24, 2021. "Diazinon". ...
Pettis, Jeff (10 January 2003). "A scientific note on Varroa destructor resistance to coumaphos in the United States" (PDF). ... Fluvalinate was followed by coumaphos, which mites also have developed resistance to. Several methods exist for monitoring ... Pyrethroid insecticide (fluvalinate) as strips Amitraz, as strips Organophosphate insecticide (Coumaphos or Check-mite) as ...
Among those acaricides used are acrinathrin, amitraz, bromopropylate, chlordimeform, coumaphos, flumethrin, and fluvalinate. ...
Organophosphorus insecticides like coumaphos, dichlofenthion, and fenchlorphos can be applied to wounds with fly larvae. These ... nagasunt and coumaphos. When trying to prevent infestation of livestock and other animals, proper spraying and dipping with ...
Pesticides such as amitraz, coumaphos, and fenthion can be used in hay bedding for prevention. The term nit has given rise to ...
2008 research by scientists from Pennsylvania State University found high levels of the miticides fluvalinate and coumaphos in ... Increased levels of the organophosphate Coumaphos in wax have been associated with decreased survivorship of developing queens ... coumaphos and fluvalinate, which are pesticides registered for use by beekeepers to control varroa mites. Studies also ...
Coumaphos bee strips (Bayer Corporation) have been approved for use in hives for the control of small hive beetles in some ...
... coumaphos (marketed as CheckMite), flumethrin (marketed as "Bayvarol" and "Polyvar Yellow"). "Soft" chemicals "Soft" chemical ...
... coumaphos MeSH D03.438.150.446.912.531 - hymecromone MeSH D03.438.150.446.912.850 - scopoletin MeSH D03.438.150.455 - ... coumaphos MeSH D03.830.219.446.912.531 - hymecromone MeSH D03.830.219.446.912.850 - scopoletin MeSH D03.830.219.455 - ...
... coumaphos MeSH D02.705.539.208 - cystaphos MeSH D02.705.539.220 - diazinon MeSH D02.705.539.245 - dimethoate MeSH D02.705. ... coumaphos MeSH D02.886.309.208 - cystaphos MeSH D02.886.309.220 - diazinon MeSH D02.886.309.245 - dimethoate MeSH D02.886. ...
... coumaphos, diazinon, dichlofenthion, fenitrothion, fenthion, parathion, parathion-methyl, pyrazophos, pyrimiphos-methyl, ...
... ether Chloromethyl methyl ether Chlorophacinone Chloroxuron Chlorthiophos Chromic chloride Cobalt carbonyl Colchicine Coumaphos ...
Testing Status of Coumaphos 10366-W. Testing Status of Coumaphos 10366-W. CASRN: 56-72-4. Formula: C14-H16-Cl-O5-P-S. Synonyms/ ...
In men with a family history of disease, there was evidence of an association between coumaphos and prostate cancer, possibly ... Coumaphos was not associated with any cancer evaluated here. ... Conclusion: Coumaphos was not associated with any cancer ... Coumaphos exposure and incident cancer among male participants in the Agricultural Health Study (AHS) Carol H Christensen 1 , ... Coumaphos exposure and incident cancer among male participants in the Agricultural Health Study (AHS) Carol H Christensen et al ...
Coumaphos may enter the environment from spillage of animal dipping and spraying solutions (U.S.EPA, 2000). Coumaphos is ... The chemical 3-chloro-7-hydroxy-4-methyl-2H-chromen-2-one/ol is a metabolite of coumaphos. First registered in 1958, coumaphos ... Coumaphos is considered to be an organophosphorus insecticide of moderate-to-high acute toxicity in animal studies. At high ... Coumaphos is highly toxic to birds and aquatic invertebrates and moderately toxic to fish. ...
Genetic Toxicity Evaluation of Coumaphos in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 342560 Summary Data. * G06 ... Evaluation of the Chronic Toxicity and Carcinogenicity of Coumaphos (56-72-4) in Male F344 Rats Exposed via Dosed Feed ... Evaluation of the Chronic Toxicity and Carcinogenicity of Coumaphos (56-72-4) in Female F344 Rats Exposed via Dosed Feed ... Evaluation of the Chronic Toxicity and Carcinogenicity of Coumaphos (56-72-4) in Male B6C3F1 Mice Exposed via Dosed Feed ...
Bioassay of Coumaphos for Possible Carcinogenicity (CASRN 56-72-4)Chemical (Study Title) ... Coumaphos: Target Organs and Levels of Evidence for TR-096. Bioassay of Coumaphos for Possible Carcinogenicity (. CASRN. 56-72- ... Coumaphos. 56-72-4. 10/25/1978. Dosed-Feed. 0,10,20 PPM/50 PER GROUP. Gulf South Research Institute. ...
EVIDENCE FOR THE SAFETY OF COUMAPHOS, DIAZINON AND MALATHION RESIDUES IN HONEY * GARCIA, MAF ...
Beyond Pesticides, October 1, 2007) For the second time in ten years, state officials have poured aquatic insecticide and piscicide rotenone into Californias Lake Davis in an effort to control an invasive species of fish, northern pike. Despite the first failure of rotenone to eradicate the pike in 1997, Fish and Game officials felt they had no alternative but to resort to the toxic chemical once more.. The invasive pike were first introduced, illegally, into Lake Davis in 1994. Since then, the population has reached uncontrollable proportions, out-competing local trout. The small town of Portola, which uses Lake Davis as its drinking water supply, is largely supported by fishing and tourism, which are boosted by its reputation for producing extremely large trout. Local businesses fear the consequences of the pikes destruction of the attraction.. Despite its economic concerns, the town did not universally support the first application of rotenone in 1997. Four residents, including the mayor ...
Beyond Pesticides, May 25, 2023) A review of scientific literature published in the Journal of Endocrinological Investigation demonstrates exposure to past and current-use endocrine-disrupting chemicals (EDCs), like pesticides, have a long history of severe adverse human health effects. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Therefore, studies related to ...
The 17 organophosphate pesticides are acephate, bensulide, chlorethoxyfos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, ...
The primary OP used was coumaphos. NIOSH investigators observed various coumaphos application tasks and administered ... Participants reported mixing coumaphos 8.5 days per month and spraying or dipping livestock 11 days per month, on average. ... These were conducted at the end of one or more coumaphos application tasks. All of the APHIS animal health technicians who met ... Three reported being removed from working with coumaphos (one time each) in the past year due to low cholinesterase levels. ...
Substances with non-approved uses such as amitraz, chlorfenvinphos and coumaphos were detected. ...
... coumaphos in those [Formula: see text]; diazinon, dichlorvos, and malathion in all participants) and three herbicides (dicamba ... coumaphos (over age 62), diazinon, permethrin, and 2,4-D. ...
Coumaphos Preferred Term Term UI T009834. Date01/01/1999. LexicalTag NON. ThesaurusID ... Coumaphos. Tree Number(s). D02.705.400.625.120. D02.705.539.345.120. D02.886.300.692.120. D03.383.663.283.446.912.326. D03.633. ... Coumaphos Preferred Concept UI. M0005256. Registry Number. L08SZ5Z5JC. Related Numbers. 56-72-4. Scope Note. A ...
Alahmed AM, Hussein HI, Kheir SM, Al-Rajhy D. Efficacy of flumethrin and coumaphos against the camel tick Hyalomma dromedarii L ... coumaphos WP formulation, were used topically against different stages of H. dromedarii on camels (16). The toxicity of ... flumethrin was 8 times higher than that of coumaphos against ticks. Some studies have shown that 1% flumethrin pour-on has 95- ...
Organophosphates, such as coumaphos, causes epileptic activity in bees brains before it shuts down their learning abilities. ...
Coumaphos - Preferred Concept UI. M0005256. Scope note. A organothiophosphorus cholinesterase inhibitor that is used as an ...
Coumaphos D2.705.539.199 D2.705.400.625.120 D2.886.309.199 D2.705.539.345.120 D2.886.300.692.120 Coumaric Acids D2.241.223.201. ...
Coumaphos Preferred Term Term UI T009834. Date01/01/1999. LexicalTag NON. ThesaurusID ... Coumaphos. Tree Number(s). D02.705.400.625.120. D02.705.539.345.120. D02.886.300.692.120. D03.383.663.283.446.912.326. D03.633. ... Coumaphos Preferred Concept UI. M0005256. Registry Number. L08SZ5Z5JC. Related Numbers. 56-72-4. Scope Note. A ...
Keywords: فریتروتیون; Coumaphos; Methyl parathion; Fenitrothion; Photodegradation; Pseudo-first order kinetics; Pseudo-second ... coumaphos; CPF; chlorpyrifos; 4-CP; 4-chlorophenol; DZN; diazinon; EDSs; edge-plane-like defective sites; EP; ethyl parathion; ...
Coumaphos Any amount ND 0.00215 µg/g 0.02 µg/g Pass Cyfluthrin 2 µg/g ND 0.05508 µg/g 0.2 µg/g Pass ...
The susceptibility to the organophosphates such as coumaphos and chlorfenvinphos of R. microplus from northeastern Mexico ... coumaphos, chlorfenvinphos, diazinon, and chlorpyrifos, and the synthetic pyrethroids (SPs) flumethrin, deltamethrin, and ... they were susceptible to coumaphos and chlorfenvinphos. Mortality rates higher than 66% were observed for lindane, indicating ...
She also noted that study results in laboratory animals found that organophosphate insecticides, such as coumaphos and ...
... coumaphos, E0301103,Cardizem,diltiazem hydrochloride, E0301121,Ondogyne,cyclofenil, E0301123,Neosar,cyclophosphamide, E0301124, ...
Coumaphos SerPl-mCnc 3 LOINC_Long_Common_Name LOINC Long Common Name Coumaphos [Mass/volume] in Serum or Plasma ...
... the organophosphate insecticides coumaphos, diazinon, dichlorvos, and malathion; and the herbicides dicamba, glyphosate, and 2, ...
  • Cumulative exposure to coumaphos was not associated with cancer risk overall or with any major cancer site including prostate. (nih.gov)
  • General population exposure to coumaphos is unlikely, though exposure through dietary meat and milk intake is possible. (cdc.gov)
  • Organophosphates, such as coumaphos , causes epileptic activity in bees' brains before it shuts down their learning abilities. (aromahealthtexas.com)
  • This study aimed to analyze the resistance status of 2 populations of R. microplus from northeastern Mexico to the organochlorine (OC) lindane, organophosphates (OP) coumaphos, chlorfenvinphos, diazinon, and chlorpyrifos, and the synthetic pyrethroids (SPs) flumethrin, deltamethrin, and cypermethrin. (bvsalud.org)
  • The susceptibility to the organophosphates such as coumaphos and chlorfenvinphos of R. microplus from northeastern Mexico should be noted. (bvsalud.org)
  • At high doses, coumaphos and other organophosphorus insecticides share a mechanism of toxicity:inhibition of the activity of acetylcholinesterase enzymes in the nervous system, resulting in excess acetylcholine at nerve terminals, and producing acute symptoms such as nausea, vomiting, cholinergic effects, weakness, paralysis, and seizures. (cdc.gov)
  • She also noted that study results in laboratory animals found that organophosphate insecticides, such as coumaphos and parathion, may contribute to increased airway reactivity. (nih.gov)
  • Substances with non-approved uses such as amitraz, chlorfenvinphos and coumaphos were detected. (foodsafetynews.com)
  • meanwhile, they were susceptible to coumaphos and chlorfenvinphos. (bvsalud.org)
  • Urine was collected for measurement of a possible urinary biomarker of coumaphos, 3-chloro-4-methyl coumarin (chlorferon), at the same times. (cdc.gov)
  • Coumaphos is an organophosphate livestock insecticide. (nih.gov)
  • First registered in 1958, coumaphos is an organophosphorus insecticide that is used to control ticks, lice, mites, and arthropod pests on beef cattle, dairy cows, swine, and certain other farm animals. (cdc.gov)
  • Once absorbed, phosphorothioates such as coumaphos are metabolically activated to the "oxon" form which has greater toxicity than the parent insecticide. (cdc.gov)
  • Coumaphos is considered to be an organophosphorus insecticide of moderate-to-high acute toxicity in animal studies. (cdc.gov)
  • except for coumaphos at 225.3 ppb, levels were generally lower in organically managed hives and the highest concentration of insecticide detected in wax from conventionally managed hives was fluvalinate at 251.5 ppb. (lupinepublishers.com)
  • Participants reported mixing coumaphos 8.5 days per month and spraying or dipping livestock 11 days per month, on average. (cdc.gov)
  • Blood was collected by venipuncture for laboratory cholinesterase measurements using the Ellman method, and by fingerstick for cholinesterase measurements by field test kit at the start of the workday (prior to use of coumaphos) and again at the end of the workday. (cdc.gov)
  • Coumaphos is highly toxic to birds and aquatic invertebrates and moderately toxic to fish. (cdc.gov)
  • Human health effects from coumaphos at low environmental doses or at biomonitored levels from low environmental exposures are unknown. (cdc.gov)
  • Biomonitoring studies of 3-chloro-7-hydroxy-4-methyl-2H-chromen-2-one/ol provide physicians and public health officials with reference values so that they can determine whether people have been exposed to higher levels of coumaphos than are found in the general population. (cdc.gov)
  • Three reported being removed from working with coumaphos (one time each) in the past year due to low cholinesterase levels. (cdc.gov)
  • Coumaphos is generally immobile in soils and can persist for up to a year in some types of soils. (cdc.gov)
  • Previous research in the Agricultural Health Study (AHS) cohort observed a positive association between coumaphos and prostate cancer in men with a family history of prostate cancer. (nih.gov)
  • This study was performed to determine the association between coumaphos and other major cancer sites and to explore the consistency of the association with prostate cancer early (1993-1999) and later (2000-2005) in AHS follow-up. (nih.gov)
  • An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Coumaphos (56-72-4). (nih.gov)
  • Coumaphos may enter the environment from spillage of animal dipping and spraying solutions (U.S.EPA, 2000). (cdc.gov)