Coronavirus
Coronavirus Infections
Coronavirus 229E, Human
Coronavirus, Bovine
Spike Glycoprotein, Coronavirus
SARS Virus
Coronavirus OC43, Human
Coronavirus, Feline
Coronaviridae
Coronavirus, Canine
Severe Acute Respiratory Syndrome
Murine hepatitis virus
Transmissible gastroenteritis virus
Infectious bronchitis virus
Coronavirus NL63, Human
Nucleocapsid Proteins
Coronavirus, Rat
Porcine Respiratory Coronavirus
Viral Envelope Proteins
Molecular Sequence Data
Feline Infectious Peritonitis
Vero Cells
Amino Acid Sequence
Cattle Diseases
Serum Albumin, Bovine
Gastroenteritis, Transmissible, of Swine
Herpesvirus 1, Bovine
Cercopithecus aethiops
Virus Replication
Base Sequence
Receptors, Virus
Viverridae
Leukemia Virus, Bovine
Diarrhea Viruses, Bovine Viral
Respiratory Tract Infections
RNA Replicase
Viral Nonstructural Proteins
Enteritis, Transmissible, of Turkeys
Viral Vaccines
Viral Matrix Proteins
Nucleocapsid
Antigens, CD13
Neutralization Tests
Open Reading Frames
Cats
Middle East
Communicable Diseases, Emerging
Cysteine Endopeptidases
Defective Viruses
Virus Internalization
Chiroptera
Swine
Tuberculosis, Bovine
Bovine Virus Diarrhea-Mucosal Disease
Dysentery
Reverse Transcriptase Polymerase Chain Reaction
Virion
Cells, Cultured
Virus Assembly
Enzootic Bovine Leukosis
Sequence Analysis, DNA
Central Nervous System Viral Diseases
Polyproteins
Nidovirales
Species Specificity
Peptidyl-Dipeptidase A
Cloning, Molecular
Cytopathogenic Effect, Viral
Viral Structural Proteins
Enzyme-Linked Immunosorbent Assay
Sequence Homology, Amino Acid
Respiratory Syncytial Virus, Bovine
Protein Structure, Tertiary
Virus Attachment
Binding Sites
Infectious Bovine Rhinotracheitis
Cat Diseases
Protein Binding
Feces
RNA, Messenger
Bovine Respiratory Disease Complex
Camels
Sequence Alignment
Cattle
Glycoproteins
Encephalopathy, Bovine Spongiform
DNA Primers
Polymerase Chain Reaction
Papain
Gene Expression Regulation, Viral
Nandiniidae
Encephalomyelitis
Viral Plaque Assay
Recombination, Genetic
Cricetinae
Electrophoresis, Polyacrylamide Gel
Cell Fusion
Models, Molecular
Herpesvirus 4, Bovine
Zoonoses
Mutation
Common Cold
Antiviral Agents
Arterivirus
Lung
Helper Viruses
Immunodeficiency Virus, Bovine
Viral Fusion Proteins
Virulence
Protein Conformation
Transcription, Genetic
Hong Kong
Cross Reactions
Dog Diseases
Disease Reservoirs
Demyelinating Diseases
Pasteurellosis, Pneumonic
Protein Processing, Post-Translational
DNA, Complementary
Fluorescent Antibody Technique
Disease Outbreaks
Torovirus
Host-Pathogen Interactions
Crystallography, X-Ray
Milk
Dogs
Peptides
Interferon Type I
Carboxypeptidases
Amino Acid Substitution
Diarrhea Virus 1, Bovine Viral
Frameshifting, Ribosomal
Genes, pol
Sensitivity and Specificity
Carcinoembryonic Antigen
Mutagenesis, Site-Directed
Membrane Fusion
Acetylesterase
Sequence Homology, Nucleic Acid
Diarrhea
Peptide Fragments
Endopeptidases
Rabbits
Recombinant Fusion Proteins
5' Untranslated Regions
Sequence Homology
Substrate Specificity
Encephalitis, Viral
Hemagglutination Tests
Cinanserin
Trypsin
Epitope Mapping
Antibodies, Neutralizing
Blotting, Western
Virus Shedding
Golgi Apparatus
Beluga Whale
Seroepidemiologic Studies
Immunoglobulin G
Hydrogen-Ion Concentration
Genetic Vectors
Glycosylation
Protein Biosynthesis
Gene Expression
Mannheimia haemolytica
Identification of a coronavirus hemagglutinin-esterase with a substrate specificity different from those of influenza C virus and bovine coronavirus. (1/86)
We have characterized the hemagglutinin-esterase (HE) of puffinosis virus (PV), a coronavirus closely related to mouse hepatitis virus (MHV). Analysis of the cloned gene revealed approximately 85% sequence identity to HE proteins of MHV and approximately 60% identity to the corresponding esterase of bovine coronavirus. The HE protein exhibited acetylesterase activity with synthetic substrates p-nitrophenyl acetate, alpha-naphthyl acetate, and 4-methylumbelliferyl acetate. In contrast to other viral esterases, no activity was detectable with natural substrates containing 9-O-acetylated sialic acids. Furthermore, PV esterase was unable to remove influenza C virus receptors from human erythrocytes, indicating a substrate specificity different from HEs of influenza C virus and bovine coronavirus. Solid-phase binding assays revealed that purified PV was unable to bind to sialic acid-containing glycoconjugates like bovine submaxillary mucin, mouse alpha1 macroglobulin or bovine brain extract. Because of the close relationship to MHV, possible implications on the substrate specificity of MHV esterases are suggested. (+info)Production, characterization, and uses of monoclonal antibodies against recombinant nucleoprotein of elk coronavirus. (2/86)
This is the first report of the production of monoclonal antibodies against elk coronavirus. The nucleoprotein gene of elk coronavirus was amplified by PCR and was cloned and expressed in a prokaryotic expression vector. Recombinant nucleocapsid protein was used to immunize mice for the production of hybridomas. Twelve hybridomas that produced monoclonal antibodies against the nucleocapsid protein of elk coronavirus were selected by an indirect fluorescent-antibody test, an enzyme-linked immunosorbent assay, and a Western blot assay. Ten of the monoclonal antibodies were of the immunoglobulin G1 (IgG1) isotype, one was IgG2a, and one was IgM. All had kappa light chains. By immunohistochemistry four monoclonal antibodies detected bovine coronavirus and elk coronavirus in formalin-fixed intestinal tissues. Antinucleoprotein monoclonal antibodies were found to be better at ruminant coronavirus detection than the anti-spike protein monoclonal antibodies. Because nucleoprotein is a more abundant antigen than spike protein in infected cells, this was not an unexpected finding. (+info)Identification of a bovine coronavirus packaging signal. (3/86)
A region of the bovine coronavirus (BCV) genome that functions as a packaging signal has been cloned. The 291-nucleotide clone shares 72% homology with the region of mouse hepatitis coronavirus (MHV) gene 1b that contains the packaging signal. RNA transcripts were packaged into both BCV and MHV virions when the cloned region was appended to a noncoronavirus RNA. This is the first identification of a BCV packaging signal. The data demonstrate that the BCV genome contains a sequence that is conserved at both the sequence and functional levels, thus broadening our insight into coronavirus packaging. (+info)Host protein interactions with the 3' end of bovine coronavirus RNA and the requirement of the poly(A) tail for coronavirus defective genome replication. (4/86)
RNA viruses have 5' and 3' untranslated regions (UTRs) that contain specific signals for RNA synthesis. The coronavirus genome is capped at the 5' end and has a 3' UTR that consists of 300 to 500 nucleotides (nt) plus a poly(A) tail. To further our understanding of coronavirus replication, we have begun to examine the involvement of host factors in this process for two group II viruses, bovine coronavirus (BCV) and mouse hepatitis coronavirus (MHV). Specific host protein interactions with the BCV 3' UTR [287 nt plus poly(A) tail] were identified using gel mobility shift assays. Competition with the MHV 3' UTR [301 nt plus poly(A) tail] suggests that the interactions are conserved for the two viruses. Proteins with molecular masses of 99, 95, and 73 kDa were detected in UV cross-linking experiments. Less heavily labeled proteins were also detected in the ranges of 40 to 50 and 30 kDa. The poly(A) tail was required for binding of the 73-kDa protein. Immunoprecipitation of UV-cross-linked proteins identified the 73-kDa protein as the cytoplasmic poly(A)-binding protein (PABP). Replication of the defective genomes BCV Drep and MHV MIDI-C, along with several mutants, was used to determine the importance of the poly(A) tail. Defective genomes with shortened poly(A) tails consisting of 5 or 10 A residues were replicated after transfection into helper virus-infected cells. BCV Drep RNA that lacked a poly(A) tail did not replicate, whereas replication of MHV MIDI-C RNA with a deleted tail was detected after several virus passages. All mutants exhibited delayed kinetics of replication. Detectable extension or addition of the poly(A) tail to the mutants correlated with the appearance of these RNAs in the replication assay. RNAs with shortened poly(A) tails exhibited less in vitro PABP binding, suggesting that decreased interactions with the protein may affect RNA replication. The data strongly indicate that the poly(A) tail is an important cis-acting signal for coronavirus replication. (+info)Protection studies on winter dysentery caused by bovine coronavirus in cattle using antigens prepared from infected cell lysates. (5/86)
Cells infected with bovine coronavirus (BCV) were solubilized with Triton X-100 to yield a cell lysate (CL) antigen having high hemagglutinating (HA) titers. The antigen gave high HA titers using rat erythrocytes, suggesting that it contained large amounts of hemagglutinin esterase (HE) antigen. The CL antigen, combined with an oil adjuvant, was tested for protective and antibody-inducing activities in cattle. Four groups (2 cattle/group) of cattle were inoculated with CL antigen having HA titers of 16 000, 4000, 1000, and 250. Another group served as untreated controls. Two intramuscular inoculations were given at an interval of 3 wk. The animals were challenged with virus 1 wk after the second inoculation. The groups immunized with the CL antigen having an HA titer of 4000 or 16 000 produced hemagglutination inhibition (HI) antibody titers of > 320 and serum neutralizing (SN) antibody titers of > 1280. These groups of animals showed no clinical abnormalities after challenge. In the groups immunized with CL antigen at an HA titer of 1000 or 250, HI antibody titers were 40 to 160 and SN titers were 80 to 640. The cattle with HI antibody titers of > or = 160 and the SN titers of > or = 640 showed no clinical signs, but the cattle with the HI antibody titer < 80 and the SN antibody titer < 160 developed watery diarrhea and fever after challenge. These results indicate that CL antigen with high HA titer induces antibody production in cattle that provides effective protection against winter dysentery. (+info)Coronavirus and Pasteurella infections in bovine shipping fever pneumonia and Evans' criteria for causation. (6/86)
Respiratory tract infections with viruses and Pasteurella spp. were determined sequentially among 26 cattle that died during two severe epizootics of shipping fever pneumonia. Nasal swab and serum samples were collected prior to onset of the epizootics, during disease progression, and after death, when necropsies were performed and lung samples were collected. Eighteen normal control cattle also were sampled at the beginning of the epizootics as well as at weekly intervals for 4 weeks. Respiratory bovine coronaviruses (RBCV) were isolated from nasal secretions of 21 and 25 cattle before and after transport. Two and 17 cattle nasally shed Pasteurella spp. before and after transport, respectively. RBCV were isolated at titers of 1 x 10(3) to 1.2 x 10(7) PFU per g of lung tissue from 18 cattle that died within 7 days of the epizootics, but not from the lungs of the remaining cattle that died on days 9 to 36. Twenty-five of the 26 lung samples were positive for Pasteurella spp., and their CFU ranged between 4.0 x 10(5) and 2.3 x 10(9) per g. Acute and subacute exudative, necrotizing lobar pneumonia characterized the lung lesions of these cattle with a majority of pneumonic lung lobes exhibiting fibronecrotic and exudative changes typical of pneumonic pasteurellosis, but other lung lobules had histological changes consisting of bronchiolitis and alveolitis typical of virus-induced changes. These cattle were immunologically naive to both infectious agents at the onset of the epizootics, but those that died after day 7 had rising antibody titers against RBCV and Pasteurella haemolytica. In contrast, the 18 clinically normal and RBCV isolation-negative cattle had high hemagglutinin inhibition antibody titers to RBCV from the beginning, while their antibody responses to P. haemolytica antigens were delayed. Evans' criteria for causation were applied to our findings because of the multifactorial nature of shipping fever pneumonia. This analysis identified RBCV as the primary inciting cause in these two epizootics. These viruses were previously not recognized as a causative agent in this complex respiratory tract disease of cattle. (+info)Identification of nucleocapsid binding sites within coronavirus-defective genomes. (7/86)
The coronavirus nucleocapsid (N) protein is a major structural component of virions that associates with the genomic RNA to form a helical nucleocapsid. N appears to be a multifunctional protein since data also suggest that the protein may be involved in viral RNA replication and translation. All of these functions presumably involve interactions between N and viral RNAs. As a step toward understanding how N interacts with viral RNAs, we mapped high-efficiency N-binding sites within BCV- and MHV-defective genomes. Both in vivo and in vitro assays were used to study binding of BCV and MHV N proteins to viral and nonviral RNAs. N-viral RNA complexes were detected in bovine coronavirus (BCV)-infected cells and in cells transiently expressing the N protein. Filter binding was used to map N-binding sites within Drep, a BCV-defective genome that is replicated and packaged in the presence of helper virus. One high-efficiency N-binding site was identified between nucleotides 1441 and 1875 at the 3' end of the N ORF within Drep. For comparative purposes N-binding sites were also mapped for the mouse hepatitis coronavirus (MHV)-defective interfering (DI) RNA MIDI-C. Binding efficiencies similar to those for Drep were measured for RNA transcripts of a region encompassing the MHV packaging signal (nts 3949-4524), as well as a region at the 3' end of the MHV N ORF (nts 4837-5197) within MIDI-C. Binding to the full-length MIDI-C transcript (approximately 5500 nts) and to an approximately 1-kb transcript from the gene 1a region (nts 935-1986) of MIDI-C that excluded the packaging signal were both significantly higher than that measured for the smaller transcripts. This is the first identification of N-binding sequences for BCV. It is also the first report to demonstrate that N interacts in vitro with sequences other than the packaging signal and leader within the MHV genome. The data clearly demonstrate that N binds coronavirus RNAs more efficiently than nonviral RNAs. The results have implications with regard to the multifunctional role of N. (+info)Temperature-sensitive acetylesterase activity of haemagglutinin-esterase specified by respiratory bovine coronaviruses. (8/86)
Numerous respiratory bovine coronaviruses (RBCV) were isolated recently from nasal swab samples and lung tissues of feedlot cattle with acute respiratory tract disease. These newly emerging RBCV isolates exhibited distinct phenotypic features that differentiated them from enteropathogenic bovine coronaviruses (EBCV). The RBCV strains had a receptor-destroying enzyme function mediated by acetylesterase (AE) activity of the haemagglutinin-esterase (HE) glycoprotein. The HE genes of wild-type EBCV strain LY138 and RBCV strains OK-0514 (OK) and LSU-94LSS-051 (LSU) were cloned, sequenced and transiently expressed in COS-7 cells. The enzymic properties of HE proteins in COS-7 cellular extracts and in purified virus preparations were assayed at room temperature, 37 degrees C and 39 degrees C by two different assays. One assay used p-nitrophenyl acetate (PNPA) as substrate and detected serine-esterase activity; the second assay monitored AE function with bovine submaxillary mucin (BSM) as substrate. The PNPA tests confirmed that HE proteins of EBCV and RBCV were functionally expressed in transfected COS-7 cells. Time-dependent determination of the AE activity of purified RBCV OK and LSU particles showed lower AE activity at 39 degrees C than at 37 degrees C, whereas the purified EBCV LY particles retained full AE activity at both 37 degrees C and 39 degrees C. Transiently expressed RBCV HE exhibited a marked reduction of AE activity after 40 min of assay time at 37 degrees C. In contrast, the AE activity of the transiently expressed EBCV HE remained stable beyond 40 min. The deduced amino-acid sequences of the HE proteins specified by the RBCV strains OK and LSU contained specific amino-acid changes in comparison with the EBCV LY strain, which may be responsible for the observed enzymic differences. These results are consistent with the hypothesis that RBCV strains have evolved to selectivelyreplicate in respiratory tissues and that HE may play a role in this tissue tropism. (+info)Coronaviruses are a group of viruses that can cause a range of respiratory illnesses, from the common cold to severe diseases such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). Coronavirus infections are caused by one of the four subtypes of coronaviruses: alpha, beta, gamma, and delta.
The symptoms of coronavirus infections can range from mild to severe and may include:
* Fever
* Cough
* Shortness of breath or difficulty breathing
* Chest tightness or discomfort
* Headache
* Sore throat
* Runny nose or stuffy nose
* Body aches or muscle pains
* Diarrhea
* Nausea or vomiting
In severe cases, coronavirus infections can lead to pneumonia, acute respiratory distress syndrome (ARDS), and even death. The virus is primarily spread through close contact with an infected person, such as touching, shaking hands, or kissing. It can also be spread by touching contaminated surfaces and objects, such as door handles, light switches, and countertops.
There are several ways to diagnose coronavirus infections, including:
* Physical examination and medical history
* Chest X-ray or CT scan
* Blood tests
* Nucleic acid test (NAT)
Treatment for coronavirus infections is primarily focused on relieving symptoms and supporting the body's immune system. This may include:
* Antiviral medications
* Oxygen therapy
* Pain relief medication
* Rest and hydration
Prevention is key to avoiding coronavirus infections, and this includes:
* Washing hands frequently with soap and water
* Using alcohol-based hand sanitizers
* Avoiding close contact with people who are sick
* Covering the mouth and nose when coughing or sneezing
* Staying home when sick
There are also several vaccines currently being developed to protect against coronavirus infections, but these are not yet widely available. It is important to follow the guidance of public health authorities and take precautions to prevent the spread of the virus.
The symptoms of SARS typically begin within 2-10 days after exposure and can include:
* Fever (>38°C)
* Chills
* Headache
* Body aches
* Fatigue
* Dry cough
* Shortness of breath or difficulty breathing
* Pneumonia
In severe cases, SARS can progress to respiratory failure, which can lead to death. The virus is highly contagious and can be spread through close contact with an infected person, as well as through contact with contaminated surfaces and objects.
SARS was first identified in 2003 in China, and it quickly spread to other countries around the world, causing a global outbreak. The World Health Organization (WHO) declared SARS a Public Health Emergency of International Concern (PHEIC) in March 2003, and it was eventually contained through a combination of measures such as isolation of infected individuals, contact tracing, and the use of personal protective equipment (PPE).
There is no specific treatment for SARS, but supportive care such as oxygen therapy and mechanical ventilation may be provided to help manage symptoms. Antiviral medications have been developed to treat SARS, but their effectiveness is still being studied. Prevention of SARS primarily relies on good hygiene practices, such as frequent handwashing, avoidance of close contact with people who are sick, and wearing PPE when caring for infected individuals.
Overall, Severe Acute Respiratory Syndrome (SARS) is a serious and potentially life-threatening respiratory illness that can be spread through close contact with an infected person. While it has been largely contained through public health measures, it remains important to continue practicing good hygiene and be aware of the risks of SARS in order to prevent its spread.
There are several types of coronaviridae infections, including:
1. Common cold: This is the most common type of coronavirus infection, and it is estimated that the common cold affects millions of people worldwide each year.
2. Seasonal flu: Some coronaviruses can cause seasonal flu, which is a more severe illness than the common cold.
3. SARS (severe acute respiratory syndrome): This is a serious and potentially life-threatening infection that was first identified in 2003.
4. MERS-CoV (Middle East respiratory syndrome coronavirus): This is another serious and potentially life-threatening infection that was first identified in 2012.
5. COVID-19: This is a viral respiratory disease that was first identified in Wuhan, China in December 2019. It has since spread to become a global pandemic.
The symptoms of coronaviridae infections can vary depending on the type of virus and the individual infected. Common symptoms include:
* Fever
* Cough
* Sore throat
* Runny nose
* Headache
* Fatigue
* Diarrhea (in some cases)
In severe cases, coronaviridae infections can lead to complications such as pneumonia, bronchitis, and sinus and ear infections. In rare cases, they can also lead to more serious conditions such as acute respiratory distress syndrome (ARDS) and multi-organ failure.
There is no specific treatment for coronaviridae infections, but antiviral medications may be prescribed in some cases. Treatment is generally focused on relieving symptoms and supporting the body's immune system. Prevention measures include good hygiene practices such as washing hands frequently, avoiding close contact with people who are sick, and wearing masks in public places. Vaccines are also being developed to prevent COVID-19 and other coronaviridae infections.
Coronaviridae infections can be diagnosed through a variety of tests, including:
* Rapid antigen tests: These tests can detect the presence of the virus in a person's nose and throat.
* PCR (polymerase chain reaction) tests: These tests can detect the genetic material of the virus in a person's respiratory tract.
* Serology tests: These tests can detect antibodies against the virus in a person's blood.
Overall, coronaviridae infections can be serious and potentially life-threatening, but with proper diagnosis and treatment, many people are able to recover from them. Prevention measures such as good hygiene practices and vaccination can also help prevent the spread of these infections.
Symptoms of FIP include loss of appetite, weight loss, fever, lethargy, and difficulty breathing. Diagnosis is based on a combination of clinical signs, laboratory tests, and imaging studies. There is no cure for FIP, and treatment is focused on managing symptoms and supporting the cat's quality of life.
Prognosis for cats with FIP is generally poor, and the disease can be fatal within weeks to months after diagnosis. However, some cats may survive for longer periods of time if they receive appropriate supportive care. Prevention is key, and vaccination against feline coronavirus (FCoV) can help reduce the risk of developing FIP.
It's important to note that while FIP is a serious disease, it is relatively rare in cats under 6 months of age, as their immature immune system does not allow the virus to progress to its final stages.
Cattle diseases refer to any health issues that affect cattle, including bacterial, viral, and parasitic infections, as well as genetic disorders and environmental factors. These diseases can have a significant impact on the health and productivity of cattle, as well as the livelihoods of farmers and ranchers who rely on them for their livelihood.
Types of Cattle Diseases
There are many different types of cattle diseases, including:
1. Bacterial diseases, such as brucellosis, anthrax, and botulism.
2. Viral diseases, such as bovine viral diarrhea (BVD) and bluetongue.
3. Parasitic diseases, such as heartwater and gapeworm.
4. Genetic disorders, such as polledness and cleft palate.
5. Environmental factors, such as heat stress and nutritional deficiencies.
Symptoms of Cattle Diseases
The symptoms of cattle diseases can vary depending on the specific disease, but may include:
1. Fever and respiratory problems
2. Diarrhea and vomiting
3. Weight loss and depression
4. Swelling and pain in joints or limbs
5. Discharge from the eyes or nose
6. Coughing or difficulty breathing
7. Lameness or reluctance to move
8. Changes in behavior, such as aggression or lethargy
Diagnosis and Treatment of Cattle Diseases
Diagnosing cattle diseases can be challenging, as the symptoms may be similar for different conditions. However, veterinarians use a combination of physical examination, laboratory tests, and medical history to make a diagnosis. Treatment options vary depending on the specific disease and may include antibiotics, vaccines, anti-inflammatory drugs, and supportive care such as fluids and nutritional supplements.
Prevention of Cattle Diseases
Preventing cattle diseases is essential for maintaining the health and productivity of your herd. Some preventative measures include:
1. Proper nutrition and hydration
2. Regular vaccinations and parasite control
3. Sanitary living conditions and frequent cleaning
4. Monitoring for signs of illness and seeking prompt veterinary care if symptoms arise
5. Implementing biosecurity measures such as isolating sick animals and quarantining new animals before introduction to the herd.
It is important to work closely with a veterinarian to develop a comprehensive health plan for your cattle herd, as they can provide guidance on vaccination schedules, parasite control methods, and disease prevention strategies tailored to your specific needs.
Conclusion
Cattle diseases can have a significant impact on the productivity and profitability of your herd, as well as the overall health of your animals. It is essential to be aware of the common cattle diseases, their symptoms, diagnosis, treatment, and prevention methods to ensure the health and well-being of your herd.
By working closely with a veterinarian and implementing preventative measures such as proper nutrition and sanitary living conditions, you can help protect your cattle from disease and maintain a productive and profitable herd. Remember, prevention is key when it comes to managing cattle diseases.
Symptoms of TGS in pigs include diarrhea, vomiting, and severe dehydration, as well as fever and lethargy. The disease can be highly fatal, especially in young piglets. In humans, the disease can cause mild to moderate gastrointestinal symptoms, such as diarrhea, vomiting, and abdominal cramps, but it is usually self-limiting and not life-threatening.
TGS is primarily spread through close contact with infected pigs or contaminated objects, such as feeders or pens. The virus can also be transmitted through the air, such as when an infected pig coughs or sneezes. Prevention and control measures include strict biosecurity practices, such as proper cleaning and disinfection of facilities, wearing personal protective equipment (PPE), and avoiding contact with infected animals. Vaccination is also available for pigs, but it is not 100% effective and may not completely prevent the spread of the disease.
Early detection and control of TGS outbreaks are critical to minimize the impact on animal health and productivity, as well as to reduce the risk of transmission to humans. Diagnosis is based on clinical signs, laboratory testing (such as PCR or ELISA), and serology. Laboratory confirmation is essential for proper diagnosis and control of the disease.
TGS has significant economic impacts on the swine industry, as it can lead to high morbidity and mortality rates in infected herds, resulting in reduced productivity and increased costs for disease management and control. In addition, TGS can have public health implications, as it can pose a risk of transmission to humans, particularly in areas where human-animal contact is more frequent or where biosecurity practices are not strictly followed. Therefore, prevention and control measures should be implemented promptly and consistently to minimize the spread of the disease and protect animal and human health.
The common types of RTIs include:
1. Common cold: A viral infection that affects the upper respiratory tract, causing symptoms such as runny nose, sneezing, coughing, and mild fever.
2. Influenza (flu): A viral infection that can affect both the upper and lower respiratory tract, causing symptoms such as fever, cough, sore throat, and body aches.
3. Bronchitis: An inflammation of the bronchial tubes, which can be caused by viruses or bacteria, resulting in symptoms such as coughing, wheezing, and shortness of breath.
4. Pneumonia: An infection of the lungs that can be caused by bacteria, viruses, or fungi, leading to symptoms such as fever, chills, coughing, and difficulty breathing.
5. Tonsillitis: An inflammation of the tonsils, which can be caused by bacteria or viruses, resulting in symptoms such as sore throat, difficulty swallowing, and bad breath.
6. Sinusitis: An inflammation of the sinuses, which can be caused by viruses, bacteria, or fungi, leading to symptoms such as headache, facial pain, and nasal congestion.
7. Laryngitis: An inflammation of the larynx (voice box), which can be caused by viruses or bacteria, resulting in symptoms such as hoarseness, loss of voice, and difficulty speaking.
RTIs can be diagnosed through physical examination, medical history, and diagnostic tests such as chest X-rays, blood tests, and nasal swab cultures. Treatment for RTIs depends on the underlying cause and may include antibiotics, antiviral medications, and supportive care to manage symptoms.
It's important to note that RTIs can be contagious and can spread through contact with an infected person or by touching contaminated surfaces. Therefore, it's essential to practice good hygiene, such as washing hands frequently, covering the mouth and nose when coughing or sneezing, and avoiding close contact with people who are sick.
There are several transmission routes for TE, including:
1. Vertical transmission from mother to egg: The virus can be passed from an infected hen to her eggs before they are laid. This means that chicks hatched from infected eggs may already have the virus inside them and will become sick soon after hatching.
2. Horizontal transmission between birds: Infected birds can transmit the virus to other birds through their feces, which can contaminate feed, water, or the environment. This is why it's important to keep poultry farms clean and hygienic to prevent the spread of disease.
3. Contact with infected birds: People who handle infected birds or their droppings can also become infected and transmit the virus to other birds.
4. Contaminated feed: Feed that is contaminated with the virus can also transmit it to birds. This is why it's important to use clean, virus-free feed and to store it properly.
There are several signs and symptoms of TE in turkeys, including:
1. Diarrhea: Affected birds may have loose, watery droppings that can be streaked with blood or mucus.
2. Vomiting: Birds may vomit their feed, which can lead to dehydration and electrolyte imbalances.
3. Dehydration: Affected birds may appear lethargic and have sunken eyes, dry mouths, and puffy wings.
4. Lack of appetite: Birds may stop eating and drinking, which can lead to weight loss and worsening of the disease.
5. Ulcers: In severe cases, the virus can cause ulcers in the intestines, which can be painful and can lead to bleeding.
6. Weight loss: Affected birds may lose weight due to a lack of appetite and dehydration.
7. Poor egg production: In laying hens, the virus can cause poor egg production or no eggs at all.
8. Mortality: The disease can be fatal in some cases, especially if left untreated or if the birds are not provided with proper care and management.
If you suspect that your flock has been exposed to TE, it's important to seek veterinary care immediately. Your veterinarian can perform diagnostic tests to confirm the presence of the virus and provide appropriate treatment. Treatment may include antibiotics to prevent secondary bacterial infections, fluid therapy to restore hydration, and supportive care to manage symptoms such as vomiting and diarrhea. In severe cases, hospitalization may be necessary to provide intensive care and monitoring.
Prevention is key when it comes to TE in turkeys. Here are some steps you can take to reduce the risk of transmission:
1. Use clean, virus-free feed and water: Make sure that all feed and water are free from contamination and are provided in clean, sanitized containers.
2. Implement good biosecurity practices: Keep the flock in a clean, well-ventilated area with minimal contact with other birds or animals. Provide separate facilities for feeding, drinking, and manure disposal to reduce the risk of transmission.
3. Vaccinate your flock: Vaccination is an effective way to prevent TE in turkeys. Work with your veterinarian to develop a vaccination program that's tailored to your flock's needs.
4. Monitor for signs of disease: Regularly check your birds for signs of illness, such as loss of appetite, lethargy, and diarrhea. If you suspect that your flock has been exposed to TE, seek veterinary care immediately.
5. Keep your flock healthy: Proper nutrition, good living conditions, and regular health check-ups can help keep your flock healthy and reduce the risk of disease transmission.
By being aware of the signs and symptoms of Turkey Enteritis and taking preventative measures to reduce the risk of transmission, you can help protect your flock and ensure the health and well-being of your birds.
The most common symptoms of bovine mastitis include:
1. Swelling and redness of the udder
2. Increased temperature of the affected quarter
3. Pain or discomfort in the udder
4. Decreased milk production
5. Abnormal milk appearance (e.g., clots, pus, or blood)
If left untreated, mastitis can lead to more severe complications such as abscesses, septicemia, or even death of the animal. Therefore, early detection and proper treatment are crucial to prevent the spread of infection and reduce the severity of clinical signs.
Diagnosis of bovine mastitis is typically based on a combination of clinical examination, milk culture, and laboratory tests (e.g., blood counts, serum biochemistry). Treatment involves antibiotics, supportive care (e.g., fluids, pain management), and identification of the underlying cause to prevent future occurrences.
Prevention of bovine mastitis is key to maintaining a healthy and productive dairy herd. This includes proper sanitation and hygiene practices, regular milking techniques, and effective dry cow therapy. Vaccination against common mastitis-causing pathogens may also be considered in some cases.
Overall, bovine mastitis is a significant health issue in dairy cattle that can have significant economic and welfare implications for farmers and the industry as a whole. Proper diagnosis, treatment, and prevention strategies are essential to maintain a healthy and productive herd.
Examples of emerging communicable diseases include SARS (severe acute respiratory syndrome), West Nile virus, and HIV/AIDS. These diseases are often difficult to diagnose and treat, and they can spread rapidly due to increased travel and trade, as well as the high level of interconnectedness in today's world.
Emerging communicable diseases can be caused by a variety of factors, such as environmental changes, genetic mutations, or the transmission of diseases from animals to humans. These diseases can also be spread through various routes, including airborne transmission, contact with infected bodily fluids, and vector-borne transmission (such as through mosquitoes or ticks).
To prevent the spread of emerging communicable diseases, it is important to have strong surveillance systems in place to detect and monitor outbreaks, as well as effective public health measures such as vaccination programs, quarantine, and contact tracing. Additionally, research into the causes and transmission mechanisms of these diseases is crucial for developing effective treatments and prevention strategies.
Overall, emerging communicable diseases pose a significant threat to global health security, and it is important for healthcare professionals, policymakers, and the general public to be aware of these diseases and take steps to prevent their spread.
A viral infection that affects the liver and is transmitted to animals through contact with infected feces, urine, or saliva. The condition can be caused by several different viruses, including hepatitis A, B, C, D, and E. Symptoms of animal hepatitis may include loss of appetite, vomiting, diarrhea, lethargy, fever, and jaundice (yellowing of the skin and eyes). In severe cases, the infection can cause liver failure and death.
Prevention:
* Avoid contact with infected animals
* Practice good hygiene, such as washing hands frequently
* Keep pets up to date on vaccinations and preventatives
* Avoid drinking water or eating food that may be contaminated with feces or urine from infected animals
* Use protective clothing and equipment when handling animals that may be infected
Treatment:
* Supportive care, such as fluids and electrolytes to prevent dehydration and maintain blood pressure
* Antiviral medications in severe cases
* Hospitalization for severe cases or those that do not respond to treatment
Prognosis:
* Depends on the severity of the infection and the underlying health status of the animal. In general, the prognosis is good for animals that receive prompt and appropriate treatment.
Complications:
* Liver failure
* Sepsis (blood infection)
* Kidney failure
* Death
Prevalence:
* Widespread in animals, especially in those that are kept in close quarters or have poor living conditions.
Affected Organ:
* Liver
The symptoms of bovine tuberculosis can vary depending on the severity of the infection and the organs affected. Common symptoms include:
* Coughing or difficulty breathing
* Weight loss and loss of condition
* Fever
* Swollen lymph nodes
* Enlarged liver or spleen
* Poor milk production in lactating cows
* Intestinal problems, such as diarrhea or constipation
If left untreated, bovine tuberculosis can lead to serious complications, such as pneumonia, pleurisy, and peritonitis. It can also spread to other animals in the herd, making it important to identify and isolate infected animals promptly.
Diagnosis of bovine tuberculosis typically involves a combination of physical examination, laboratory tests, and imaging studies. Skin tests, such as the Mantoux test or the single-dose intradermal test, can detect exposure to the bacteria, but they may not always provide accurate results in animals with low levels of antibodies. Blood tests, such as the interferon gamma (IFN-γ) test or the QuantiFERON® test, can detect the presence of TB antigens in the blood, but these tests may also have limitations.
Treatment of bovine tuberculosis typically involves a combination of antibiotics and supportive care to manage symptoms and prevent complications. The most commonly used antibiotics include isoniazid, streptomycin, and pyrazinamide. In severe cases, surgical intervention may be necessary to remove infected tissue or repair damaged organs.
Prevention of bovine tuberculosis primarily involves controlling the spread of the disease through control of the mycobacteria that cause it. Measures such as testing and removal of infected animals, use of clean needles and equipment, and proper disposal of animal carcasses can help prevent the spread of the disease. Additionally, vaccination of animals with a live bacille Calmette-Guérin (BCG) vaccine has been shown to be effective in preventing TB infections.
In conclusion, bovine tuberculosis is a significant health concern for cattle and other animals, as well as humans who may be exposed to infected animals or contaminated products. Early diagnosis and treatment are essential to prevent the spread of the disease and manage symptoms in affected animals. Prevention measures such as testing and removal of infected animals, use of clean needles and equipment, and proper disposal of animal carcasses can help control the spread of the disease.
The disease is typically transmitted through close contact with infected animals, and can be spread through respiratory droplets, contaminated feces, or contaminated surfaces. The virus can also be transmitted from dam to fetus during pregnancy, causing congenital BVD.
BVD-MD is characterized by acute diarrhea, vomiting, and fever, as well as mucosal lesions in the gastrointestinal tract. In severe cases, it can lead to dehydration, electrolyte imbalances, and even death.
Diagnosis of BVD-MD is typically made through a combination of clinical signs, laboratory tests such as PCR or ELISA, and histopathological examination of tissue samples. There is no specific treatment for the disease, but supportive care such as fluids, electrolytes, and antibiotics may be provided to manage symptoms.
Prevention of BVD-MD includes vaccination of animals at risk, strict biosecurity measures, and separation of infected animals from healthy ones. Control programs should also include testing of animals for the presence of the virus and monitoring of herds for signs of the disease.
1. Bacterial dysentery: This type of dysentery is caused by bacteria such as Shigella or Salmonella and is typically spread through contaminated food or water. Symptoms include diarrhea, fever, abdominal cramps, and blood in the stool.
2. Amebic dysentery: This type of dysentery is caused by a parasite called Entamoeba histolytica and is typically spread through contaminated food or water. Symptoms include diarrhea, fever, abdominal pain, and blood in the stool.
Dysentery can be diagnosed through a physical examination, medical history, and laboratory tests such as stool samples or blood tests. Treatment typically involves antibiotics for bacterial dysentery and antiparasitic medication for amebic dysentery. In severe cases, hospitalization may be necessary to manage symptoms and prevent complications such as dehydration and electrolyte imbalances.
Prevention measures for dysentery include:
* Practicing good hygiene, such as washing hands frequently and avoiding close contact with people who are sick
* Avoiding contaminated food and water
* Properly storing and preparing food to prevent bacterial growth
* Avoiding risky behaviors such as anal sex, which can increase the risk of contracting amebic dysentery.
The prognosis for dysentery is generally good if treated promptly and effectively. However, if left untreated, it can lead to serious complications such as dehydration, electrolyte imbalances, and potentially life-threatening infections.
Symptoms of EBL can vary widely and may include:
* Swollen lymph nodes
* Chronic diarrhea
* Weight loss
* Anemia
* Lethargy
* Enlarged spleen and liver
* Neoplastic diseases such as lymphosarcoma, leukemia, or other types of cancer.
EBL is usually diagnosed through a combination of physical examination, blood tests, and biopsies. There is no cure for EBL, and treatment is primarily focused on managing symptoms and preventing the spread of the disease.
Prevention of EBL includes:
* Testing herds for BLV regularly
* Avoiding close contact between animals
* Practicing good hygiene and sanitation
* Implementing strict biosecurity measures
* Eliminating infected animals from the herd
It is important to note that EBL is not a reportable disease in all countries, and testing for BLV may not be mandatory in all regions. However, it is still important for farmers and veterinarians to be aware of the risk of EBL and take appropriate measures to prevent its spread.
Some common examples of CNSVD include:
1. Herpes simplex virus (HSV) encephalitis: This is an inflammation of the brain caused by the herpes simplex virus. It can cause fever, headache, confusion, and seizures.
2. West Nile virus (WNV) encephalitis: This is an infection of the brain caused by the West Nile virus, which is transmitted through the bite of an infected mosquito. Symptoms can include fever, headache, muscle weakness, and confusion.
3. Japanese encephalitis (JE): This is a viral infection that affects the brain and is transmitted through the bite of an infected mosquito. Symptoms can include fever, headache, seizures, and changes in behavior or cognitive function.
4. Rabies: This is a viral infection that affects the brain and is transmitted through the bite of an infected animal, usually a dog, bat, or raccoon. Symptoms can include fever, headache, agitation, and changes in behavior or cognitive function.
5. Enteroviral encephalitis: This is an infection of the brain caused by enteroviruses, which are common viruses that affect the gastrointestinal tract. Symptoms can include fever, vomiting, diarrhea, and changes in behavior or cognitive function.
The diagnosis of CNSVD typically involves a combination of physical examination, laboratory tests (such as blood tests or lumbar puncture), and imaging studies (such as CT or MRI scans). Treatment options vary depending on the specific disease and may include antiviral medications, supportive care, and rehabilitation.
Prevention of CNSVD includes avoiding exposure to mosquitoes and other vectors that can transmit disease, maintaining good hygiene practices (such as washing hands frequently), and getting vaccinated against diseases such as rabies and measles. In addition, taking steps to prevent head trauma and using protective equipment when engaging in activities that involve risk of head injury can help reduce the risk of CNSVD.
Overall, while central nervous system viral diseases can be serious and potentially life-threatening, early diagnosis and treatment can improve outcomes and prevent long-term complications. It is important to seek medical attention promptly if symptoms persist or worsen over time.
Symptoms of IBR can include fever, coughing, sneezing, runny eyes, and loss of appetite. In severe cases, the disease can lead to pneumonia, meningitis, and even death. The virus is highly adaptable and can survive for long periods of time in the environment, making it difficult to control and eliminate from infected herds.
Diagnosis of IBR is based on a combination of clinical signs, laboratory tests, and serology. Treatment typically involves supportive care, such as antibiotics and anti-inflammatory medications, and isolation of infected animals to prevent further spread of the disease. Vaccination is also an important tool in controlling IBR outbreaks, and several vaccines are available for use in cattle.
Prevention of IBR primarily involves good husbandry practices, such as regular cleaning and disinfection of facilities, proper feeding and watering, and avoiding close contact between animals from different herds. The disease is also reportable to animal health authorities, and strict biosecurity measures are in place to prevent the spread of the virus to other farms and regions.
IBR is a significant economic burden on the cattle industry worldwide, as it can lead to reduced productivity, increased mortality rates, and trade restrictions due to the risk of disease transmission to other animals and humans. Therefore, early detection, effective treatment, and strict control measures are essential for controlling outbreaks and minimizing the impact of IBR on animal health and the economy.
1. Feline Leukemia Virus (FeLV): This is a highly contagious virus that weakens the immune system, making cats more susceptible to other infections and cancer.
2. Feline Immunodeficiency Virus (FIV): Similar to HIV in humans, this virus attacks the immune system and can lead to a range of secondary infections and diseases.
3. Feline Infectious Peritonitis (FIP): A viral disease that causes fluid accumulation in the abdomen and chest, leading to difficulty breathing and abdominal pain.
4. Feline Lower Urinary Tract Disease (FLUTD): A group of conditions that affect the bladder and urethra, including urinary tract infections and kidney stones.
5. Feline Diabetes: Cats can develop diabetes, which can lead to a range of complications if left untreated, including urinary tract infections, kidney disease, and blindness.
6. Feline Hyperthyroidism: An overactive thyroid gland that can cause weight loss, anxiety, and heart problems if left untreated.
7. Feline Cancer: Cats can develop various types of cancer, including lymphoma, leukemia, and skin cancer.
8. Dental disease: Cats are prone to dental problems, such as tartar buildup, gum disease, and tooth resorption.
9. Obesity: A common problem in cats, obesity can lead to a range of health issues, including diabetes, arthritis, and heart disease.
10. Behavioral disorders: Cats can develop behavioral disorders such as anxiety, stress, and aggression, which can impact their quality of life and relationships with humans.
It's important to note that many of these diseases can be prevented or managed with proper care, including regular veterinary check-ups, vaccinations, parasite control, a balanced diet, exercise, and mental stimulation. Additionally, early detection and treatment can significantly improve the outcome for cats with health issues.
The main components of BRDC are:
1. Viral respiratory diseases (such as Infectious Bovine Rhinotracheitis virus and Bovine Viral Diarrhea virus)
2. Bacterial pneumonia (such as Pasteurella multocida and Haemophilus somnus)
3. Environmental stressors (such as dust, ammonia, and high temperatures)
4. Secondary bacterial infections (such as Staphylococcus aureus and Streptococcus agalactiae)
The signs of BRDC can vary depending on the specific cause and severity of the disease, but may include:
1. Nasal discharge
2. Coughing
3. Sneezing
4. Lethargy
5. Decreased appetite
6. Fever
7. Pneumonia
8. Pleuritis (inflammation of the lining around the lungs)
9. Peritonitis (inflammation of the lining of the abdomen)
BRDC is typically diagnosed based on a combination of clinical signs, laboratory tests, and imaging studies such as radiography or ultrasonography. Treatment may include antibiotics, anti-inflammatory medications, and supportive care such as fluids and nutritional supplements.
Prevention is key to managing BRDC, and this includes:
1. Vaccination against viral respiratory diseases
2. Good herd management practices, such as proper sanitation, ventilation, and animal husbandry
3. Avoiding stressful conditions and providing adequate nutrition and water
4. Monitoring for early signs of disease and seeking prompt veterinary care if symptoms arise
5. Isolation of infected animals to prevent spread of the disease.
Symptoms of BSE include:
* Behavioral changes, such as aggression or confusion
* Loss of coordination and balance
* Weakness or paralysis of the limbs
* Vision problems
* Difficulty swallowing or chewing
* Change in vocalization or bellowing
BSE is transmitted through the consumption of contaminated beef products, such as meat and bonemeal, which contain the abnormal prion protein. The disease can also be spread through blood transfusions or other medical procedures using infected material.
There is no cure for BSE, and it is typically diagnosed through a combination of clinical signs, necropsy, and laboratory tests such as the polymerase chain reaction (PCR) or Western blotting.
Prevention of BSE includes:
* Implementing strict controls on the handling and disposal of animal carcasses and tissues
* Avoiding the use of meat and bonemeal in animal feed
* Ensuring proper sterilization and safety protocols in medical procedures
* Monitoring and testing for the presence of the disease in cattle populations.
BSE has significant economic and public health implications, as it can lead to the loss of entire herds and the closure of livestock markets, as well as the potential for human transmission through the consumption of contaminated beef products.
The symptoms of encephalomyelitis can vary depending on the cause and severity of the condition. Common symptoms include fever, headache, neck stiffness, muscle weakness, confusion, seizures, and loss of sensation or paralysis in parts of the body. In severe cases, encephalomyelitis can lead to life-threatening complications such as brain damage, stroke, and respiratory failure.
The diagnosis of encephalomyelitis is based on a combination of clinical features, laboratory tests, and imaging studies. Laboratory tests may include blood tests to detect the presence of inflammatory markers or antibodies against specific infectious agents. Imaging studies such as CT or MRI scans can help to identify inflammation in the brain and spinal cord.
Treatment of encephalomyelitis depends on the underlying cause of the condition. In some cases, antiviral medications may be used to treat infections such as herpes simplex or West Nile virus. In other cases, corticosteroids may be prescribed to reduce inflammation and prevent further damage. Supportive care such as intravenous fluids, oxygen therapy, and physical therapy may also be necessary to manage symptoms and promote recovery.
In conclusion, encephalomyelitis is a serious condition that can cause significant morbidity and mortality. Early diagnosis and prompt treatment are essential to prevent complications and improve outcomes for patients with this condition.
A type of pneumonia caused by a viral infection. The most common viruses that cause pneumonia are the respiratory syncytial virus (RSV), influenza virus, and adenovirus.
Symptoms include fever, cough, chest pain, difficulty breathing, and loss of appetite.
Treatment typically involves antiviral medications and supportive care to manage symptoms and improve lung function. In severe cases, hospitalization may be necessary.
Prevention measures include vaccination against the flu and RSV, good hygiene practices such as frequent handwashing, and avoiding close contact with people who are sick.
Zoonoses (zoonosis) refers to infectious diseases that can be transmitted between animals and humans. These diseases are caused by a variety of pathogens, including bacteria, viruses, parasites, and fungi, and can be spread through contact with infected animals or contaminated animal products.
Examples of Zoonoses
Some common examples of zoonoses include:
1. Rabies: a viral infection that can be transmitted to humans through the bite of an infected animal, typically dogs, bats, or raccoons.
2. Lyme disease: a bacterial infection caused by Borrelia burgdorferi, which is spread to humans through the bite of an infected blacklegged tick (Ixodes scapularis).
3. Toxoplasmosis: a parasitic infection caused by Toxoplasma gondii, which can be transmitted to humans through contact with contaminated cat feces or undercooked meat.
4. Leptospirosis: a bacterial infection caused by Leptospira interrogans, which is spread to humans through contact with contaminated water or soil.
5. Avian influenza (bird flu): a viral infection that can be transmitted to humans through contact with infected birds or contaminated surfaces.
Transmission of Zoonoses
Zoonoses can be transmitted to humans in a variety of ways, including:
1. Direct contact with infected animals or contaminated animal products.
2. Contact with contaminated soil, water, or other environmental sources.
3. Through vectors such as ticks, mosquitoes, and fleas.
4. By consuming contaminated food or water.
5. Through close contact with an infected person or animal.
Prevention of Zoonoses
Preventing the transmission of zoonoses requires a combination of personal protective measures, good hygiene practices, and careful handling of animals and animal products. Some strategies for preventing zoonoses include:
1. Washing hands frequently, especially after contact with animals or their waste.
2. Avoiding direct contact with wild animals and avoiding touching or feeding stray animals.
3. Cooking meat and eggs thoroughly to kill harmful bacteria.
4. Keeping pets up to date on vaccinations and preventative care.
5. Avoiding consumption of raw or undercooked meat, particularly poultry and pork.
6. Using insect repellents and wearing protective clothing when outdoors in areas where vectors are prevalent.
7. Implementing proper sanitation and hygiene practices in animal housing and husbandry.
8. Implementing strict biosecurity measures on farms and in animal facilities to prevent the spread of disease.
9. Providing education and training to individuals working with animals or in areas where zoonoses are prevalent.
10. Monitoring for and reporting cases of zoonotic disease to help track and control outbreaks.
Conclusion
Zoonoses are diseases that can be transmitted between animals and humans, posing a significant risk to human health and animal welfare. Understanding the causes, transmission, and prevention of zoonoses is essential for protecting both humans and animals from these diseases. By implementing appropriate measures such as avoiding contact with wild animals, cooking meat thoroughly, keeping pets up to date on vaccinations, and implementing proper sanitation and biosecurity practices, we can reduce the risk of zoonotic disease transmission and protect public health and animal welfare.
The symptoms of the common cold can vary depending on the individual and the virus that is causing the infection. Some of the most typical symptoms include:
Fever (less than 102°F)
Runny or stuffy nose
Sneezing
Coughing
Headache
Sore throat
Fatigue
Muscle aches
The common cold is usually diagnosed based on symptoms and medical history. There is no cure for the common cold, but over-the-counter medications can help alleviate some of the symptoms. Antiviral medications are not effective against the common cold because it is caused by a virus, not bacteria.
Preventive measures for the common cold include:
Washing your hands frequently
Avoiding close contact with people who have colds
Not touching your eyes, nose, or mouth
Staying hydrated
Getting enough sleep
Exercising regularly
Eating a healthy diet
There are many myths and misconceptions about the common cold that can lead to confusion and inappropriate treatment. Some of these include:
Chicken soup is not an effective treatment for colds.
Antibiotics do not work against viral infections such as the common cold.
Over-the-counter medications such as decongestants and antihistamines can have side effects and are not always effective.
Drinking plenty of fluids does help to thin out mucus and keep your body hydrated, but it will not cure a cold.
The common cold is usually a self-limiting illness that resolves on its own within one week. However, people with weakened immune systems or other underlying health conditions may experience more severe symptoms or complications such as bronchitis, pneumonia, or sinusitis. In these cases, medical attention may be necessary.
1. Common cold: A viral infection that affects the upper respiratory tract and causes symptoms such as sneezing, running nose, coughing, and mild fever.
2. Influenza (flu): A viral infection that can cause severe respiratory illness, including pneumonia, bronchitis, and sinus and ear infections.
3. Measles: A highly contagious viral infection that causes fever, rashes, coughing, and redness of the eyes.
4. Rubella (German measles): A mild viral infection that can cause fever, rashes, headache, and swollen lymph nodes.
5. Chickenpox: A highly contagious viral infection that causes fever, itching, and a characteristic rash of small blisters on the skin.
6. Herpes simplex virus (HSV): A viral infection that can cause genital herpes, cold sores, or other skin lesions.
7. Human immunodeficiency virus (HIV): A viral infection that attacks the immune system and can lead to acquired immunodeficiency syndrome (AIDS).
8. Hepatitis B: A viral infection that affects the liver, causing inflammation and damage to liver cells.
9. Hepatitis C: Another viral infection that affects the liver, often leading to chronic liver disease and liver cancer.
10. Ebola: A deadly viral infection that causes fever, vomiting, diarrhea, and internal bleeding.
11. SARS (severe acute respiratory syndrome): A viral infection that can cause severe respiratory illness, including pneumonia and respiratory failure.
12. West Nile virus: A viral infection that can cause fever, headache, and muscle pain, as well as more severe symptoms such as meningitis or encephalitis.
Viral infections can be spread through contact with an infected person or contaminated surfaces, objects, or insects such as mosquitoes. Prevention strategies include:
1. Practicing good hygiene, such as washing hands frequently and thoroughly.
2. Avoiding close contact with people who are sick.
3. Covering the mouth and nose when coughing or sneezing.
4. Avoiding sharing personal items such as towels or utensils.
5. Using condoms or other barrier methods during sexual activity.
6. Getting vaccinated against certain viral infections, such as HPV and hepatitis B.
7. Using insect repellents to prevent mosquito bites.
8. Screening blood products and organs for certain viruses before transfusion or transplantation.
Treatment for viral infections depends on the specific virus and the severity of the illness. Antiviral medications may be used to reduce the replication of the virus and alleviate symptoms. In severe cases, hospitalization may be necessary to provide supportive care such as intravenous fluids, oxygen therapy, or mechanical ventilation.
Prevention is key in avoiding viral infections, so taking the necessary precautions and practicing good hygiene can go a long way in protecting oneself and others from these common and potentially debilitating illnesses.
1. Parvovirus (Parvo): A highly contagious viral disease that affects dogs of all ages and breeds, causing symptoms such as vomiting, diarrhea, and severe dehydration.
2. Distemper: A serious viral disease that can affect dogs of all ages and breeds, causing symptoms such as fever, coughing, and seizures.
3. Rabies: A deadly viral disease that affects dogs and other animals, transmitted through the saliva of infected animals, and causing symptoms such as aggression, confusion, and paralysis.
4. Heartworms: A common condition caused by a parasitic worm that infects the heart and lungs of dogs, leading to symptoms such as coughing, fatigue, and difficulty breathing.
5. Ticks and fleas: These external parasites can cause skin irritation, infection, and disease in dogs, including Lyme disease and tick-borne encephalitis.
6. Canine hip dysplasia (CHD): A genetic condition that affects the hip joint of dogs, causing symptoms such as arthritis, pain, and mobility issues.
7. Osteosarcoma: A type of bone cancer that affects dogs, often diagnosed in older dogs and causing symptoms such as lameness, swelling, and pain.
8. Allergies: Dog allergies can cause skin irritation, ear infections, and other health issues, and may be triggered by environmental factors or specific ingredients in their diet.
9. Gastric dilatation-volvulus (GDV): A life-threatening condition that occurs when a dog's stomach twists and fills with gas, causing symptoms such as vomiting, pain, and difficulty breathing.
10. Cruciate ligament injuries: Common in active dogs, these injuries can cause joint instability, pain, and mobility issues.
It is important to monitor your dog's health regularly and seek veterinary care if you notice any changes or abnormalities in their behavior, appetite, or physical condition.
The most common demyelinating diseases include:
1. Multiple sclerosis (MS): An autoimmune disease that affects the CNS, including the brain, spinal cord, and optic nerves. MS causes inflammation and damage to the myelin sheath, leading to a range of symptoms such as muscle weakness, vision problems, and cognitive difficulties.
2. Acute demyelination: A sudden, severe loss of myelin that can be caused by infections, autoimmune disorders, or other factors. This condition can result in temporary or permanent nerve damage.
3. Chronic inflammatory demyelination (CIDP): A rare autoimmune disorder that causes progressive damage to the myelin sheath over time. CIDP can affect the CNS and the peripheral nervous system (PNS).
4. Moore's disease: A rare genetic disorder that results in progressive demyelination of the CNS, leading to a range of neurological symptoms including muscle weakness, seizures, and cognitive difficulties.
5. Leukodystrophies: A group of genetic disorders that affect the development or function of myelin-producing cells in the CNS. These conditions can cause progressive loss of myelin and result in a range of neurological symptoms.
Demyelinating diseases can be challenging to diagnose, as the symptoms can be similar to other conditions and the disease progression can be unpredictable. Treatment options vary depending on the specific condition and its severity, and may include medications to reduce inflammation and modulate the immune system, as well as rehabilitation therapies to help manage symptoms and improve quality of life.
The symptoms of pneumonic pasteurellosis in humans include fever, cough, chest pain, and difficulty breathing. In severe cases, the infection can lead to respiratory failure, sepsis, and death.
Pasteurellosis, Pneumonic is diagnosed through a combination of physical examination, medical history, and laboratory tests such as blood cultures and chest x-rays. Treatment typically involves antibiotics and supportive care, such as oxygen therapy and mechanical ventilation, to manage symptoms and prevent complications.
Prevention of pneumonic pasteurellosis includes avoiding close contact with infected animals, wearing protective clothing and equipment when handling animals, and properly cleaning and disinfecting animal products and facilities. Vaccination of animals is also recommended to reduce the risk of transmission to humans.
A disease that affects pigs, including viral, bacterial, and parasitic infections, as well as genetic disorders and nutritional deficiencies. Some common swine diseases include:
1. Porcine Reproductive and Respiratory Syndrome (PRRS): A highly contagious viral disease that can cause reproductive failure, respiratory problems, and death.
2. Swine Influenza: A viral infection similar to human influenza, which can cause fever, coughing, and pneumonia in pigs.
3. Erysipelas: A bacterial infection that causes high fever, loss of appetite, and skin lesions in pigs.
4. Actinobacillosis: A bacterial infection that can cause pneumonia, arthritis, and abscesses in pigs.
5. Parasitic infections: Such as gastrointestinal parasites like roundworms and tapeworms, which can cause diarrhea, anemia, and weight loss in pigs.
6. Scrapie: A degenerative neurological disorder that affects pigs and other animals, causing confusion, aggression, and eventually death.
7. Nutritional deficiencies: Such as a lack of vitamin E or selenium, which can cause a range of health problems in pigs, including muscular dystrophy and anemia.
8. Genetic disorders: Such as achondroplasia, a condition that causes dwarfism and deformities in pigs.
9. Environmental diseases: Such as heat stress, which can cause a range of health problems in pigs, including respiratory distress and death.
It's important to note that many swine diseases have similar symptoms, making accurate diagnosis by a veterinarian essential for effective treatment and control.
Symptoms of enteritis may include diarrhea, abdominal pain, fever, nausea, vomiting, and weight loss. In severe cases, the condition can lead to dehydration, electrolyte imbalances, and even death if left untreated.
The diagnosis of enteritis is typically made through a combination of physical examination, medical history, and diagnostic tests such as endoscopy, imaging studies, and laboratory tests (e.g., blood tests, stool cultures). Treatment depends on the underlying cause of the condition and may include antibiotics, anti-inflammatory medications, and supportive care to manage symptoms.
There are several types of diarrhea, including:
1. Acute diarrhea: This type of diarrhea is short-term and usually resolves on its own within a few days. It can be caused by a viral or bacterial infection, food poisoning, or medication side effects.
2. Chronic diarrhea: This type of diarrhea persists for more than 4 weeks and can be caused by a variety of conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or celiac disease.
3. Diarrhea-predominant IBS: This type of diarrhea is characterized by frequent, loose stools and abdominal pain or discomfort. It can be caused by a variety of factors, including stress, hormonal changes, and certain foods.
4. Infectious diarrhea: This type of diarrhea is caused by a bacterial, viral, or parasitic infection and can be spread through contaminated food and water, close contact with an infected person, or by consuming contaminated food.
Symptoms of diarrhea may include:
* Frequent, loose, and watery stools
* Abdominal cramps and pain
* Bloating and gas
* Nausea and vomiting
* Fever and chills
* Headache
* Fatigue and weakness
Diagnosis of diarrhea is typically made through a physical examination, medical history, and laboratory tests to rule out other potential causes of the symptoms. Treatment for diarrhea depends on the underlying cause and may include antibiotics, anti-diarrheal medications, fluid replacement, and dietary changes. In severe cases, hospitalization may be necessary to monitor and treat any complications.
Prevention of diarrhea includes:
* Practicing good hygiene, such as washing hands frequently and thoroughly, especially after using the bathroom or before preparing food
* Avoiding close contact with people who are sick
* Properly storing and cooking food to prevent contamination
* Drinking safe water and avoiding contaminated water sources
* Avoiding raw or undercooked meat, poultry, and seafood
* Getting vaccinated against infections that can cause diarrhea
Complications of diarrhea can include:
* Dehydration: Diarrhea can lead to a loss of fluids and electrolytes, which can cause dehydration. Severe dehydration can be life-threatening and requires immediate medical attention.
* Electrolyte imbalance: Diarrhea can also cause an imbalance of electrolytes in the body, which can lead to serious complications.
* Inflammation of the intestines: Prolonged diarrhea can cause inflammation of the intestines, which can lead to abdominal pain and other complications.
* Infections: Diarrhea can be a symptom of an infection, such as a bacterial or viral infection. If left untreated, these infections can lead to serious complications.
* Malnutrition: Prolonged diarrhea can lead to malnutrition and weight loss, which can have long-term effects on health and development.
Treatment of diarrhea will depend on the underlying cause, but may include:
* Fluid replacement: Drinking plenty of fluids to prevent dehydration and replace lost electrolytes.
* Anti-diarrheal medications: Over-the-counter or prescription medications to slow down bowel movements and reduce diarrhea.
* Antibiotics: If the diarrhea is caused by a bacterial infection, antibiotics may be prescribed to treat the infection.
* Rest: Getting plenty of rest to allow the body to recover from the illness.
* Dietary changes: Avoiding certain foods or making dietary changes to help manage symptoms and prevent future episodes of diarrhea.
It is important to seek medical attention if you experience any of the following:
* Severe diarrhea that lasts for more than 3 days
* Diarrhea that is accompanied by fever, blood in the stool, or abdominal pain
* Diarrhea that is severe enough to cause dehydration or electrolyte imbalances
* Diarrhea that is not responding to treatment
Prevention of diarrhea includes:
* Good hand hygiene: Washing your hands frequently, especially after using the bathroom or before preparing food.
* Safe food handling: Cooking and storing food properly to prevent contamination.
* Avoiding close contact with people who are sick.
* Getting vaccinated against infections that can cause diarrhea, such as rotavirus.
Overall, while diarrhea can be uncomfortable and disruptive, it is usually a minor illness that can be treated at home with over-the-counter medications and plenty of fluids. However, if you experience severe or persistent diarrhea, it is important to seek medical attention to rule out any underlying conditions that may require more formal treatment.
A type of encephalitis caused by a virus that inflames the brain and spinal cord, leading to fever, headache, confusion, seizures, and in severe cases, coma or death. Viral encephalitis is usually transmitted through the bite of an infected mosquito or tick, but can also be spread through contact with infected blood or organs. Diagnosis is made through a combination of physical examination, laboratory tests, and imaging studies. Treatment typically involves supportive care, such as intravenous fluids, oxygen therapy, and medication to manage fever and seizures, as well as antiviral medications in severe cases.
Synonyms: viral encephalitis
Antonyms: bacterial encephalitis
Similar term: meningitis
1. Hantavirus pulmonary syndrome (HPS): This is a severe respiratory disease caused by the hantavirus, which is found in the urine and saliva of infected rodents. Symptoms of HPS can include fever, headache, muscle pain, and difficulty breathing.
2. Leptospirosis: This is a bacterial infection caused by the bacterium Leptospira, which is found in the urine of infected rodents. Symptoms can include fever, headache, muscle pain, and jaundice (yellowing of the skin and eyes).
3. Rat-bite fever: This is a bacterial infection caused by the bacterium Streptobacillus moniliformis, which is found in the saliva of infected rodents. Symptoms can include fever, headache, muscle pain, and swollen lymph nodes.
4. Lymphocytic choriomeningitis (LCM): This is a viral infection caused by the lymphocytic choriomeningitis virus (LCMV), which is found in the urine and saliva of infected rodents. Symptoms can include fever, headache, muscle pain, and meningitis (inflammation of the membranes surrounding the brain and spinal cord).
5. Tularemia: This is a bacterial infection caused by the bacterium Francisella tularensis, which is found in the urine and saliva of infected rodents. Symptoms can include fever, headache, muscle pain, and swollen lymph nodes.
These are just a few examples of the many diseases that can be transmitted to humans through contact with rodents. It is important to take precautions when handling or removing rodents, as they can pose a serious health risk. If you suspect that you have been exposed to a rodent-borne disease, it is important to seek medical attention as soon as possible.
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Rotavirus6
- We conducted a taxonomic analysis of raw FASTQ files using Kraken version 1 and MiniKraken DB ( https://ccb.jhu.edu/software/kraken ), which showed 15,582 kobuvirus sequence reads in addition to sequences for E. coli , coronavirus, and rotavirus. (cdc.gov)
- Real-time reverse transcription PCR showed 4/9 samples were positive for BKV by cycle thresholds of 23.0 (case IL35146), 29.97 (case IL37122), 32.84 (case IL50179), and 33.61 (case IL34890) but were negative for coronavirus, rotavirus, and bovine viral diarrhea virus ( Appendix Table 2). (cdc.gov)
- Do not vaccinate calves with oral Coronavirus or Rotavirus products within 5 days of administering First Defense. (animalhealthusa.com)
- Efficacy of the bovine rotavirus (BRV) fraction of ScourGuard 4KC was demonstrated in 2 challenge studies conducted by Zoetis Inc. Healthy neonatal calves were removed from their dams prior to nursing, and were fed colostrum collected from heifers previously vaccinated with either ScourGuard 4KC or a placebo. (drugs.com)
- The Giardia lamblia- Cryptosporidium-Rotavirus-Coronvirus Antigen Combo Test is a rapid diagnostic tool for detecting Giardia bovine antigen, Cryptosporidium bovine antigen, bovine rotavirus antigen, and bovine coronavirus antigen. (hwtai.com)
- Symptoms of young cattle infected with Giardia bovis, Cryptosporidium bovis, bovine rotavirus, and bovine coronvirus are similar, which can cause and dehydration in sick cattle. (hwtai.com)
Porcine2
- Another added bonus is that the Air Mini just got FDA-cleared for the destruction of viruses and bacteria, and can inactivate up to 99.99% of H1N1 and coronavirus (bovine/porcine) strains. (iwantmedia.com)
- Whole genome analysis of selected human and animal rotaviruses identified in Uganda from 2012 to 2014 reveals complex genome reassortment events between human, bovine, caprine and porcine strains. (cdc.gov)
Genome11
- Genome organization and phylogenic tree of bovine kobuvirus IL35164 isolated from cattle, United States. (cdc.gov)
- Genome Sequence of Bovine Coronavirus Variants from the Nasal Virome of Irish Beef Suckler and Pre-weaned Dairy Calves Clinically Diagnosed with Bovine Respiratory Disease. (bvsalud.org)
- We report 24 bovine coronavirus (BCoV) genome sequences from Ireland . (bvsalud.org)
- A cDNA fragment representing the hemagglutinin-esterase (HE) gene of bovine coronavirus (BVC) was inserted into the genome of Autographa californica nuclear polyhedrosis virus. (illinois.edu)
- Coronaviruses are single-stranded RNA viruses with some unique characteristics such as the possession of a very large nucleic acid, high infidelity of the RNA-dependent polymerase, and high rate of mutation and recombination in the genome. (who.int)
- 1. A bulged stem-loop structure in the 3' untranslated region of the genome of the coronavirus mouse hepatitis virus is essential for replication. (nih.gov)
- 3. Characterization of the RNA components of a putative molecular switch in the 3' untranslated region of the murine coronavirus genome. (nih.gov)
- 5. Host protein interactions with the 3' end of bovine coronavirus RNA and the requirement of the poly(A) tail for coronavirus defective genome replication. (nih.gov)
- 6. Characterization of an essential RNA secondary structure in the 3' untranslated region of the murine coronavirus genome. (nih.gov)
- 7. An optimal cis-replication stem-loop IV in the 5' untranslated region of the mouse coronavirus genome extends 16 nucleotides into open reading frame 1. (nih.gov)
- 15. A hypervariable region within the 3' cis-acting element of the murine coronavirus genome is nonessential for RNA synthesis but affects pathogenesis. (nih.gov)
Glycoprotein4
- Cleavage of the bovine herpesvirus glycoprotein B is not essential for its function. (microbiologyresearch.org)
- Glycoprotein IV of bovine herpesvirus 1-expressing cell line complements and rescues a conditionally lethal viral mutant. (microbiologyresearch.org)
- Parker, MD , Yoo, D & Babiuk, LA 1990, ' Expression and secretion of the bovine coronavirus hemagglutinin-esterase glycoprotein by insect cells infected with recombinant baculoviruses ', Journal of virology , vol. 64, no. 4, pp. 1625-1629. (illinois.edu)
- The S glycoprotein of coronaviruses is important for viral entry and pathogenesis with most variable sequences. (mdpi.com)
Manufactures the coronavirus2
- Coronavirus Dog Laboratories manufactures the coronavirus in dogs reagents distributed by Genprice. (iowaodes.com)
- Coronavirus Plant Laboratories manufactures the coronavirus face plant reagents distributed by Genprice. (urokinases.com)
Antigen1
- The mAbs generated from those hybridomas could be used as a reagent (second Ab) of anti-human immunoglobins in a diagnostic assay for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the virus that causes COVID-19 (coronavirus disease 2019) and other assays that detect antigen specific antibodies from human sera. (nih.gov)
Infection4
- The findings not only unveil the direct antiviral activity of CIGB-325 on coronavirus infection but also provide molecular clues underlying such effect and reinforce the scientific rationality behind the pharmacologic inhibition of CK2 to treat coronav virus infections. (semanticscholar.org)
- It is intended for diagnosing and monitoring of patients related to infection by SARS Coronavirus. (iowaodes.com)
- Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis. (greenmedinfo.com)
- A history of smoking may lead to a more severe coronavirus infection. (greenmedinfo.com)
SARS Coronavirus2
- Description: For the qualitative determination of IgG class antibodies against SARS Coronavirus in Human serum or plasma. (iowaodes.com)
- In less than two decades, three members of the group, severe acute respiratory syndrome (SARS) coronavirus (CoV), Middle East respiratory syndrome (MERS)-CoV, and SARS-COV-2, have emerged causing disease outbreaks that affected millions and claimed the lives of thousands of people. (who.int)
Calves4
- We detected bovine kobuvirus (BKV) in calves with diarrhea in the United States. (cdc.gov)
- To further screen BKV in bovine samples, we designed primers and probes (sequences available upon request) targeting 3D to test 9 additional intestinal samples from necropsied calves. (cdc.gov)
- BCoV was sequenced directly from nasal swabs that had been collected during a bovine respiratory disease (BRD) outbreak among recently purchased beef suckler and pre-weaned dairy calves. (bvsalud.org)
- A species of CORONAVIRUS infecting neonatal calves, presenting as acute diarrhea, and frequently leading to death. (nih.gov)
MERS-CoV2
- Some of them have caused worldwide panic as emerging human pathogens in recent years, e.g., severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). (nature.com)
- En moins de deux décennies, trois membres du groupe, le coronavirus (CoV) du syndrome respiratoire aigu sévère (SRAS), le syndrome respiratoire du Moyen-Orient (MERS)-CoV et le SRAS-COV-2, sont apparus, provoquant des épidémies qui ont touché des millions et des personnes. (who.int)
Pandemic3
- Further, different companies operating in the bovine serum albumin market have also experienced negative impacts of the pandemic in the past year. (medgadget.com)
- He speculates on his website that the coronavirus pandemic "is actually a bioweapon attack and may be linked to the U.S. anthrax attack of 2001. (politifact.com)
- Failing to protect farmers amid the novel coronavirus disease (COVID-19) pandemic can worsen India's agrarian distress. (org.in)
Causative2
Vaccine3
- The research article is baseless - there is no evidence that the coronavirus vaccine causes Alzheimer's, ALS or prion diseases. (politifact.com)
- All he includes is a three-sentence methods section summarizing an unspecified analysis of the coronavirus vaccine. (politifact.com)
- The live-attenuated vaccine candidates are based on a recombinant chimeric bovine/human parainfluenza virus 3 (rB/HPIV3) vector expressing prefusion-stabilized versions of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike (S) protein. (nih.gov)
Species1
- Description: Human coronavirus 229E is a single-stranded, positive-sense, RNA virus species in the Alphacoronavirus genus of the subfamily Coronavirinae, in the family Coronaviridae, of the order Nidovirales. (iowaodes.com)
20173
- In 2017, another coronavirus, the swine acute diarrhea syndrome (SADS) coronavirus (SADS-CoV) emerged in animals killing over 24,000 piglets in China. (who.int)
- En 2017, un autre coronavirus, le coronavirus du syndrome de la diarrhée aiguë du porc (SADS) (SADS-CoV) est apparu chez des animaux tuant plus de 24000 porcelets en Chine. (who.int)
- A New Bat-HKU2-like Coronavirus in Swine, China, 2017. (cdc.gov)
Severe3
- In the past 12 years, two emerging infectious diseases-severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)-attacked humans and animals worldwide and caused approximately 774 human deaths and 315 human deaths, respectively ( http://www.who.int/csr/sars/country/table2004_04_21/en/ , http://www.who.int/csr/don/2014_07_23_mers/en/ ). (nature.com)
- 9. Putative cis-acting stem-loops in the 5' untranslated region of the severe acute respiratory syndrome coronavirus can substitute for their mouse hepatitis virus counterparts. (nih.gov)
- Vaccination has proven highly effective against severe acute res-piratory syndrome coronavirus 2 (SARS-CoV-2), but the long-term immunogenicity and the functional preserved im-mune responses of vaccines are needed to inform evolving evi-dence-based guidelines for boosting schedules. (bvsalud.org)
229E3
- There are four globally distributed known human coronaviruses - HCoV-229E, HCoV-HKU1, HC0V-NL63 and HCoV-OC43, which are found in different locations around the world at different times of the year. (iowaodes.com)
- Coronavirus 229E and Human coronavirus OC43 are known to be the cause for the common cold. (iowaodes.com)
- Additionally, between the Coronaviruses, HCoV-229E is the most frequently co-detected with other respiratory viruses, mainly with HRSV (Human respiratory syncytial virus). (iowaodes.com)
Serum13
- The Coronavirus In Dogs reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (iowaodes.com)
- The bovine serum albumin market has been estimated to experience significant growth opportunities in the forthcoming years. (medgadget.com)
- Bovine serum albumin is extracted from the blood plasma of cows. (medgadget.com)
- The immunoassay applications of bovine serum albumin include immunocytochemistry and enzyme-linked immunosorbent assay. (medgadget.com)
- Further, chemicals and enzymes, food and beverages, marine biotechnology and aquaculture, animal breeding, and biotechnology are some of the industries that use bovine serum albumin. (medgadget.com)
- The bovine serum albumin is the protein that can be used as a by-product of cheese because of the cost its economical nature. (medgadget.com)
- Various research organizations are using bovine serum albumin as the protein standard. (medgadget.com)
- It has been used in order to determine unknown quantities of some other proteins while keeping in mind the quantities of bovine serum albumin. (medgadget.com)
- In addition to this, the bovine serum albumin does not put any noteworthy effects on various biochemical reactions. (medgadget.com)
- High solubility in water and highly pure nature are some of the other prominent characteristics that are estimated to boost opportunities in the bovine serum albumin market. (medgadget.com)
- The key players operating in the bovine serum albumin market have been adopting different strategies to fuel growth opportunities in the forthcoming years. (medgadget.com)
- The bovine serum albumin market is spread across different geographical locations around the world including North America, Asia Pacific, Europe, the Middle East & Africa, and Latin America. (medgadget.com)
- TVMDL also has a Bovine Comprehensive Abortion Serology Panel to investigate infectious bovine abortion utilizing serum from heifers or cows that suffered pregnancy loss. (tamu.edu)
Infections1
- RÉSUMÉ L'émergence d'une nouvelle souche de coronavirus dans la Péninsule arabique a soulevé des inquiétudes sanitaires à l'échelle mondiale en 2012, d'une part parce que la majorité des infections humaines ont été mortelles et d'autre part parce qu'une origine animale était suspectée. (who.int)
Calf2
- Coronavirus as an agent of neonatal calf diarrhea in a Chinese dairy cattle farm. (nih.gov)
- FIRST DEFENSE is a capsule containing antibodies which aid in the reduction of morbidity and mortality from neonatal calf scours caused by K99+ E. coli and bovine coronavirus. (animalhealthusa.com)
Variants1
- You may have heard about the new variants of SARS-CoV-2-the coronavirus that causes COVID-19-that have appeared in other parts of the world and have now been detected in the United States. (nih.gov)
Interspecies2
- Many coronaviruses are capable of interspecies transmission. (nature.com)
- 13. Construction of murine coronavirus mutants containing interspecies chimeric nucleocapsid proteins. (nih.gov)
Single-stranded1
- Since coronavirus NL63 is a positive single-stranded RNA virus, the processes of replication via transcription and translation can be carried out in the cytoplasm of the infected cell. (iowaodes.com)
Coli1
- Neutralizing antibodies against bovine coronavirus as well as antibodies specific for E. coli K99+ pilus antigens present in FIRST DEFENSE are prepared from hyperimmune bovine colostrum. (animalhealthusa.com)
Murine3
- Expression of bovine herpesvirus 1 glycoproteins gI and gIII in transfected murine cells. (microbiologyresearch.org)
- 4. Genetic evidence of a long-range RNA-RNA interaction between the genomic 5' untranslated region and the nonstructural protein 1 coding region in murine and bovine coronaviruses. (nih.gov)
- 8. Characterization of a murine coronavirus defective interfering RNA internal cis-acting replication signal. (nih.gov)
Vaccines4
- Coronavirus vaccines developed by Pfizer-BioNTech and Moderna have not been linked to neurodegenerative or prion diseases. (politifact.com)
- In the article , published in the journal Microbiology & Infectious Diseases in January, J. Bart Classen wrote that components of the coronavirus vaccines may cause the misfolding of proteins associated with Alzheimer's and Lou Gehrig's disease, also known as amyotrophic lateral sclerosis. (politifact.com)
- The coronavirus vaccines use a new but well-researched technology called mRNA, which tells the body how to produce copies of the protein on the surface of the virus without infecting the patient. (politifact.com)
- The Food and Drug Administration has granted emergency use authorization to two coronavirus vaccines: one from Pfizer-BioNTech and one from Moderna. (politifact.com)
Infectious1
- This plan was created to assist with the investigation of etiologic agents that may cause infectious bovine abortion as well as pathophysiology that may explain loss of pregnancy close to expected parturition. (tamu.edu)
Disease1
- A report of family case of coronavirus disease 2019 (COVID-19) confirmed in Wuhan and treated using the combination of western medicine and Chinese traditional patent medicine Shuanghuanglian oral liquid. (greenmedinfo.com)
Prevalence1
- The high prevalence of coronaviruses in domestic and wild animals, especially bats and birds, and the propensity for their genomes to undergo mutation and recombination may lead to emergence of new coronaviruses that could pose a serious threat to human and animal health. (who.int)
Replication3
- This is followed by an outline of the unique replication strategy adopted by coronaviruses. (nih.gov)
- 10. A U-turn motif-containing stem-loop in the coronavirus 5' untranslated region plays a functional role in replication. (nih.gov)
- 14. Stem-loop III in the 5' untranslated region is a cis-acting element in bovine coronavirus defective interfering RNA replication. (nih.gov)
Characteristics1
- This review aims to summarize current data describing the characteristics of bovine coronavirus (BCV) and the three clinical syndromes with which this virus is associated. (nih.gov)
Protein3
- 11. Targeted RNA recombination of the membrane and nucleocapsid protein genes between mouse hepatitis virus and bovine coronavirus. (nih.gov)
- 18. An interaction between the nucleocapsid protein and a component of the replicase-transcriptase complex is crucial for the infectivity of coronavirus genomic RNA. (nih.gov)
- Description: Coronavirus, natural protein. (urokinases.com)
Genes1
- In order to assess their threat to humans, we explored to infer the potential hosts of coronaviruses using a dual-model approach based on nineteen parameters computed from spike genes of coronaviruses. (nature.com)
Virus5
- Coronavirus NL63 is not an emerging virus, but rather one that continually circulates the human population. (iowaodes.com)
- Les coronavirus sont des virus à ARN simple brin avec certaines caractéristiques uniques telles que la possession d'un très grand acide nucléique, une infidélité élevée de la polymérase dépendante de l'ARN, et un taux élevé de mutation et de recombinaison dans le génome. (who.int)
- L'Organisation mondiale de la Santé a invité des experts en santé publique et scientifiques à une réunion urgente en janvier 2013, étant donné les connaissances limitées disponibles sur l'évolution épidémiologique et naturelle de l'infection par ce nouveau virus. (who.int)
- Pendant la réunion, les données disponibles ont été examinées et des lacunes critiques dans les connaissances ont été identifiées en vue d'améliorer la compréhension du risque pour la santé publique associé à ce virus, d'intensifier la préparation et de préserver et de protéger la santé mondiale. (who.int)
- SARS-CoV-2 is a virus of the Coronavirus family that has emerged as a major public health concern. (nih.gov)