Coronary Angiography
Coronary Artery Disease
Angioplasty, Balloon, Coronary
Pericardium
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Coronary Disease
Coronary Artery Bypass
Blood Vessels
Coronary Restenosis
Myocardial Infarction
Coronary Vessel Anomalies
Dogs
Coronary Aneurysm
Myocardium
Coronary Thrombosis
Endothelium, Vascular
Stents
Nitroglycerin
Vasodilation
Vascular Resistance
Treatment Outcome
Risk Factors
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Coronary Occlusion
Ultrasonography, Interventional
Prospective Studies
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Percutaneous Coronary Intervention
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Adenosine
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Follow-Up Studies
Hemodynamics
Tomography, X-Ray Computed
Blood Flow Velocity
Vasoconstriction
Magnetic Resonance Angiography
Coronary Care Units
Neovascularization, Physiologic
Acetylcholine
Models, Cardiovascular
Quail
Coturnix
Sensitivity and Specificity
Nitric Oxide
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Severity of Illness Index
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Exercise Test
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Tunica Media
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.
Tunica Intima
Sirolimus
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Feasibility Studies
Myocardial Revascularization
Coronary Artery Bypass, Off-Pump
Collateral Circulation
Paracrine Communication
Chick Embryo
Cardiac Catheterization
NG-Nitroarginine Methyl Ester
Angina Pectoris
Platelet Aggregation Inhibitors
Heart Ventricles
Image Processing, Computer-Assisted
Immunohistochemistry
Risk Assessment
Vascular Endothelial Growth Factor A
The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
Drug-Eluting Stents
Nitric Oxide Synthase
Morphogenesis
Gene Expression Regulation, Developmental
Echocardiography
Dipyridamole
Cardiovascular Agents
Prognosis
Myocardial Reperfusion
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
Arterioles
Fractional Flow Reserve, Myocardial
Mammary Arteries
Vasomotor System
Cell Differentiation
Multidetector Computed Tomography
Ticlopidine
Mucocutaneous Lymph Node Syndrome
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.
Ventricular Function, Left
Hyperemia
Stem Cells
Angina Pectoris, Variant
Multivariate Analysis
Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Tomography, Emission-Computed, Single-Photon
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Chi-Square Distribution
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Vascular Calcification
Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
Myocardial Perfusion Imaging
Ergonovine
Constriction, Pathologic
Postoperative Complications
Arteriosclerosis
Endothelial Cells
Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.
Radial Artery
Disease Models, Animal
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Tomography, Spiral Computed
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
Incidence
Logistic Models
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Hypercholesterolemia
Angina, Stable
Hypertension
Neovascularization, Pathologic
Proportional Hazards Models
Thallium Radioisotopes
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Atherosclerosis
Dose-Response Relationship, Drug
Stroke Volume
C-Reactive Protein
Angioplasty, Balloon
Cholesterol, LDL
Registries
Papaverine
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Myocardial Reperfusion Injury
Dobutamine
Cardiovascular Diseases
Isosorbide Dinitrate
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Dilatation, Pathologic
Analysis of Variance
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Swine, Miniature
Cardiopulmonary Bypass
Sex Factors
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Cholesterol
Microvascular Angina
ANGINA PECTORIS or angina-like chest pain with a normal coronary arteriogram and positive EXERCISE TEST. The cause of the syndrome is unknown. While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). It is different from METABOLIC SYNDROME X, a syndrome characterized by INSULIN RESISTANCE and HYPERINSULINEMIA, that has increased risk for cardiovascular disease.
Carotid Arteries
Hospital Mortality
Myocardial Bridging
Cholesterol, HDL
Platelet Glycoprotein GPIIb-IIIa Complex
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
Diabetes Complications
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Kaplan-Meier Estimate
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Odds Ratio
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Lipids
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Fistula
Risk
Cardiotonic Agents
Adrenergic beta-Antagonists
Arterio-Arterial Fistula
Internal Mammary-Coronary Artery Anastomosis
Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Bradykinin
A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.
Nitroprusside
Pulmonary Artery
ROC Curve
Survival Analysis
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Heart Diseases
Rabbits
Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures. (1/8389)
We studied phasic right coronary blood flow in well trained normal dogs and dogs with pulmonic stenosis. We installed electromagnetic flow transducers and pressure tubes under anesthesia to monitor right coronary blood flow, cardiac output, central aortic blood pressure, and right ventribular pressure. In normotensive dogs, systolic flow amplitude equaled early diastolic flow levels. The ratio of systolic to diastolic flow at rest was substantially greater in the right coronary bed (36+/-1.3%) than in the left circumflex bed (13+/-3.6%). Right diastolid flow runoff, including the cove late in diastole, resembled left circumflex runoff. Blood flow to the normotensive right (37+/-1.1 ml/min 100(-1) g) and the left (35+/-1.0 ml/min(-1) g) ventricular myocardium indicated equal perfusion of both cardiac walls. Throttling of systolic flow was related directly to the right ventricular systolic pressure level in the dogs with pulmonic stenosis. Retrograde systolic flow occurred in severe right ventricular hypertension. The late diastolic runoff pattern in dogs with pulmonic stenosis appeared the same as for the normotensive dogs. We obtained systolic to diastolic flow ratios of 1/3 the value of normotensive hearts in high and severe pulmonic hypertension. Electrocardiograms and studies of pathology suggested restricted blood flow to the inner layers of the right myocardium in the dogs with severe and high right ventricular hypertension. Normotensive and hypertensive peak hyperemic flow responses were similar, except for an increased magnitude of diastolic flow, with proportionately less systolic flow in hypertensive states. (+info)The effect of cardiac contraction on collateral resistance in the canine heart. (2/8389)
We determined whether the coronary collateral vessels develop an increased resistance to blood flow during systole as does the cognate vascular bed. Collateral resistance was estimated by measuring retrograde flow rate from a distal branch of the left anterior descending coronary artery while the main left coronary artery was perfused at a constant pressure. Retrograde flow rate was measured before and during vagal arrest. We found that in 10 dogs the prolonged diastole experienced when the heart was stopped caused no significant change in the retrograde flow rate, which indicated that systole has little effect on the collateral resistance. However, when left ventricular end-diastolic pressure was altered by changing afterload or contractility, a direct relationship between end-diastolic pressure and collateral resistance was noted. (+info)Variations in 35SO4 incorporation into glycosaminoglycans along canine coronary arteries. A possible index of artery wall stress. (3/8389)
Focal areas of accentuated wall stress along the course of canine coronary arteries may be revealed by the level of 35SO4 incorporation into glycosaminoglycans (GAG). In the anterior descending artery, 35SO4 incorporation in higher in the proximal than in the distal region and may be extraordinarily high as the vessel enters a proximally located muscle bridge and at the takeoff region of multidirectional branches. In the circumflex artery, the incorporation also is higher in the proximal than in the distal region and is high at the genu where the posterior descending artery forms. There are differences in uptake of 35SO4 in vessels even when the arteries arise from the same vascular bed.this was shown by the higher incorporation in the left coronary artery than in the right coronary artery. A general anatomical agreement exists between these sites of high 35SO4 incorporation and previously described locations of interval elastic disruption ans proliferation of intimal connective tissue in the dog. (+info)Site of myocardial infarction. A determinant of the cardiovascular changes induced in the cat by coronary occlusion. (4/8389)
The influence of site of acute myocardial infarction on heart rate, blood pressure, cardiac output, total peripheral resistance (TPR), cardiac rhythm, and mortality was determined in 58 anesthetized cats by occlusion of either the left anterior descending (LAD), left circumflex or right coronary artery. LAD occlusion resulted in immediate decrease in cardiac output, heart rate, and blood pressure, an increase in TPR, and cardiac rhythm changes including premature ventricular beats, ventricular tachycardia, and occasionally ventricular fibrillation. The decrease in cardiac output and increase in TPR persisted in the cats surviving a ventricular arrhythmia. In contrast, right coronary occlusion resulted in a considerably smaller decrease in cardiac output. TPR did not increase, atrioventricular condition disturbances were common, and sinus bradycardia and hypotension persisted in the cats recovering from an arrhythmia. Left circumflex ligation resulted in cardiovascular changes intermediate between those produced by occlusion of the LAD or the right coronary artery. Mortality was similar in each of the three groups. We studied the coronary artery anatomy in 12 cats. In 10, the blood supply to the sinus node was from the right coronary artery and in 2, from the left circumflex coronary artery. The atrioventricular node artery arose from the right in 9 cats, and from the left circumflex in 3. The right coronary artery was dominant in 9 cats and the left in 3. In conclusion, the site of experimental coronary occlusion in cats is a major determinant of the hemodynamic and cardiac rhythm changes occurring after acute myocardial infarction. The cardiovascular responses evoked by ligation are related in part to the anatomical distribution of the occluded artery. (+info)Inhibition of endothelium-dependent hyperpolarization by endothelial prostanoids in guinea-pig coronary artery. (5/8389)
1. In smooth muscle of the circumflex coronary artery of guinea-pig, acetylcholine (ACh, 10(-6) M) produced an endothelium-dependent hyperpolarization consisting of two components. An initial component that occurs in the presence of ACh and a slow component that developed after ACh had been withdrawn. Each component of the hyperpolarization was accompanied by an increase in membrane conductance. 2. Indomethacin (5 x 10(-6) M) or diclofenac (10(-6) M), both inhibitors of cyclooxygenase, abolished only the slow hyperpolarization. The initial hyperpolarization was not inhibited by diclofenac nor by nitroarginine, an inhibitor of nitric oxide synthase. 3. Both components of the ACh-induced hyperpolarization were abolished in the presence of atropine (10(-6) M) or high-K solution ([K+]0 = 29.4 mM). 4. The interval between ACh-stimulation required to generate an initial hyperpolarization of reproducible amplitude was 20 min or greater, but it was reduced to less than 5 min after inhibiting cyclooxygenase activity. Conditioning stimulation of the artery with substance P (10(-7) M) also caused a long duration (about 20 min) inhibition of the ACh-response. 5. The amplitude of the hyperpolarization generated by Y-26763, a K+-channel opener, was reproducible within 10 min after withdrawal of ACh. 6. Exogenously applied prostacyclin (PGI2) hyperpolarized the membrane and reduced membrane resistance in concentrations over 2.8 x 10(-9)M. 7. At concentrations below threshold for hyperpolarization and when no alteration of membrane resistance occurred, PGI2 inhibited the initial component of the ACh-induced hyperpolarization. 8. It is concluded that endothelial prostanoids, possibly PGI2, have an inhibitory action on the release of endothelium-derived hyperpolarizing factor. (+info)A comparison of an A1 adenosine receptor agonist (CVT-510) with diltiazem for slowing of AV nodal conduction in guinea-pig. (6/8389)
1. The purpose of this study was to compare the pharmacological properties (i.e. the AV nodal depressant, vasodilator, and inotropic effects) of two AV nodal blocking agents belonging to different drug classes; a novel A1 adenosine receptor (A1 receptor) agonist, N-(3(R)-tetrahydrofuranyl)-6-aminopurine riboside (CVT-510), and the prototypical calcium channel blocker diltiazem. 2. In the atrial-paced isolated heart, CVT-510 was approximately 5 fold more potent to prolong the stimulus-to-His bundle (S-H interval), a measure of slowing AV nodal conduction (EC50 = 41 nM) than to increase coronary conductance (EC50 = 200 nM). At concentrations of CVT-510 (40 nM) and diltiazem (1 microM) that caused equal prolongation of S-H interval (approximately 10 ms), diltiazem, but not CVT-510, significantly reduced left ventricular developed pressure (LVP) and markedly increased coronary conductance. CVT-510 shortened atrial (EC50 = 73 nM) but not the ventricular monophasic action potentials (MAP). 3. In atrial-paced anaesthetized guinea-pigs, intravenous infusions of CVT-510 and diltiazem caused nearly equal prolongations of P-R interval. However, diltiazem, but not CVT-510, significantly reduced mean arterial blood pressure. 4. Both CVT-510 and diltiazem prolonged S-H interval, i.e., slowed AV nodal conduction. However, the A1 receptor-selective agonist CVT-510 did so without causing the negative inotropic, vasodilator, and hypotensive effects associated with diltiazem. Because CVT-510 did not affect the ventricular action potential, it is unlikely that this agonist will have a proarrythmic action in ventricular myocardium. (+info)Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice. (7/8389)
1. Isometric tension was recorded in isolated rings of aorta, carotid, coronary and mesenteric arteries taken from endothelial nitric oxide synthase knockout mice (eNOS(-/-) mice) and the corresponding wild-type strain (eNOS(+/+) mice). The membrane potential of smooth muscle cells was measured in coronary arteries with intracellular microelectrodes. 2. In the isolated aorta, carotid and coronary arteries from the eNOS(+/+) mice, acetylcholine induced an endothelium-dependent relaxation which was inhibited by N(omega)-L-nitro-arginine. In contrast, in the mesenteric arteries, the inhibition of the cholinergic relaxation required the combination of N(omega)-L-nitro-arginine and indomethacin. 3. The isolated aorta, carotid and coronary arteries from the eNOS(-/-) mice did not relax in response to acetylcholine. However, acetylcholine produced an indomethacin-sensitive relaxation in the mesenteric artery from eNOS(-/-) mice. 4. The resting membrane potential of smooth muscle cells from isolated coronary arteries was significantly less negative in the eNOS(-/-) mice (-64.8 +/- 1.8 mV, n = 20 and -58.4 +/- 1.9 mV, n = 17, for eNOS(+/+) and eNOS(-/-) mice, respectively). In both strains, acetylcholine, bradykinin and substance P did not induce endothelium-dependent hyperpolarizations whereas cromakalim consistently produced hyperpolarizations (- 7.9 +/- 1.1 mV, n = 8 and -13.8 +/- 2.6 mV, n = 4, for eNOS(+/+) and eNOS(-/-) mice, respectively). 5. These findings demonstrate that in the blood vessels studied: (1) in the eNOS(+/+) mice, the endothelium-dependent relaxations to acetylcholine involve either NO or the combination of NO plus a product of cyclo-oxygenase but not EDHF; (2) in the eNOS(-/-) mice, NO-dependent responses and EDHF-like responses were not observed. In the mesenteric arteries acetylcholine releases a cyclo-oxygenase derivative. (+info)In-stent neointimal proliferation correlates with the amount of residual plaque burden outside the stent: an intravascular ultrasound study. (8/8389)
BACKGROUND: The aim of this study was to evaluate the relationship between residual plaque burden after coronary stent implantation and the development of late in-stent neointimal proliferation. METHODS AND RESULTS: Between January 1996 and May 1997, 50 patients underwent intravascular ultrasound (IVUS) interrogation at 6+/-1.2 months after coronary stent implantation in native coronary arteries. IVUS images were acquired with a motorized pullback, and cross-sectional measurements were performed within the stents at 1-mm intervals. The following measurements were obtained: (1) lumen area (LA), (2) stent area (SA), (3) area delimited by the external elastic membrane (EEMA), (4) percent neointimal area calculated as (SA-LA/SA)x100, and (5) percent residual plaque area calculated as (EEMA-SA)/EEMAx100. Volume measurements within the stented segments were calculated by applying Simpson's rule. In the pooled data analysis of 876 cross sections, linear regression showed a significant positive correlation between percent residual plaque area and percent neointimal area (r=0.50, y= 45.03+0.29x, P<0.01). There was significant incremental increase in mean percent neointimal area for stepwise increase in percent residual plaque area. Mean percent neointimal area was 16.3+/-10.3% for lesions with a percent residual plaque area of <50% and 27.7+/-11% for lesions with a percent residual plaque area of >/=50% (P<0.001). The volumetric analysis showed that the percent residual plaque volume was significantly greater in restenotic lesions compared with nonrestenotic lesions (58.7+/-4.3% versus 51.4+/-5.7%, respectively; P<0.01). CONCLUSIONS: Late in-stent neointimal proliferation has a direct correlation with the amount of residual plaque burden after coronary stent implantation, supporting the hypothesis that plaque removal before stent implantation may reduce restenosis. (+info)
muscle cell in human body human coronary artery smooth muscle cells 2 - Anatomy Chart Body
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Patient-specific 3D hemodynamics modelling of left coronary artery under hyperemic conditions - ePrints - Newcastle University
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Coronary Anatomy for the Interventionalist | Interventional Cardiology, 2e | AccessCardiology | McGraw-Hill Medical
HKU Scholars Hub: Consequences of reduced production of NO on vascular reactivity of porcine coronary arteries after...
NewYork-Presbyterian Queens - Heart Conditions in Adults - Coronary Heart Disease
NewYork-Presbyterian Queens - Heart Conditions in Adults - Coronary Heart Disease
HUVEC, Aortic, and Coronary Artery Endothelial Cells
Enhanced Endothelin-B-Receptor-Mediated Vasoconstriction of Small Porcine Coronary Arteries in Diet-Induced...
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Anterior interventricular groove | definition of Anterior interventricular groove by Medical dictionary
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Efficacy of coronary stenting versus balloon angioplasty in small coronary arteries<...
Quantitative autoradiography reveals higher densities of specific calcitonin-gene-related peptide receptors in small...
대동맥판막 치환술 재수술 후 발생한 우관상동맥 개구부 협착
Angiotensin II-Induced Leukocyte Adhesion on Human Coronary Endothelial Cells Is Mediated by E-Selectin | Circulation Research
Faculty | Programs in Biomedical and Biological Science
Vascular supply of the anterior interventricular epicardial nerves and ventricular Purkinje fibers in the porcine hearts -...
Coronary Artery Disease
ROLE OF ALPHA(2)-ADRENOCEPTORS IN NORMAL AND ATHEROSCLEROTIC HUMAN CORONARY CIRCULATION | Università degli Studi della Campania...
Abstract 190: Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and...
Effects of Persantin (RA8), A New Coronary Vasodilator, on Coronary Blood Flow and Cardiac Dynamics in the Dog | Circulation...
Impact of plaques in the left coronary artery on wall shear stress and pressure gradient in coronary side branches
The evolution and investigation of native coronary arteries in patients after coronary stent implantations: a study by 320...
Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans - Full Text View -...
Coronary Circulation Anatomy : Coronary Anatomy Example Gallery Free Download. Coronary Circulation Anatomy. ~ Jouefct.Com
Accelerated Coronary Plaque Progression and Endothelial Dysfunction | JACC: Cardiovascular Imaging
Role of monocyte chemotactic protein 1|(mcp1)in diagnosis of patients with atherosclerotic coronary artery disease for...
Coronary Artery Spasm Symptoms - York Cardiology
5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts |...
Paper: Streptococcus mutans Cnm Protein Facilitates Invasion of CASMC (AADR Annual Meeting (March 21-24, 2012))
Angina Due to Coronary Microvascular Disease in Hypertensive Patients without Left Ventricular Hypertrophy<...
JCI -
Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis.
Coronary vessel wall MRI at 3.0 T using Time-Resolved Acquisition of Phase-Sensitive DIR (TRAPD): initial results in patients...
Coronary Endothelial Dysfunction after Drug-Eluting Stent Implantation | Science Publications
EARLY CORONARY ARTERY DISEASE FOUND IN ASYMPTOMATIC INDIVIDUALS - WorldPath Health
Coronary Calcium Scoring
| Pacific Life
Coronary angiography - Conservapedia
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Pulmonary vein thrombosis is
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Preserved coronary arteriolar dilatation in patients with type 2 diabetes mellitus: Implications for reactive oxygen species<...
Importance of cumulative exposure to elevated cholesterol and blood pressure in development of atherosclerotic coronary artery...
Global & China Coronary Stent Industry 2014 Research Report: ReportsnReports.com - Market Research Reports Library
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Circulatory system
Coronary vessels. Main article: Coronary circulation. The heart itself is supplied with oxygen and nutrients through a small " ... The coronary circulation begins near the origin of the aorta by two coronary arteries: the right coronary artery and the left ... The cardiovascular (from Latin words meaning "heart" and "vessel") system comprises the blood, heart, and blood vessels.[3] The ... After nourishing the heart muscle, blood returns through the coronary veins into the coronary sinus and from this one into the ...
Estradiol
Estrogen affects certain blood vessels. Improvement in arterial blood flow has been demonstrated in coronary arteries.[37] ... "17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart ...
Carotid endarterectomy
Left main or multi vessel coronary artery disease. Need for open heart surgery within 30 days. Left ventricular ejection ... The internal, common and external carotid arteries are carefully identified, controlled with vessel loops, and clamped. The ...
Safety of electronic cigarettes
Nicotine constricts blood vessels. This includes coronary blood vessels and those in the skin. However, blood vessels in the ... Nicotine does promote the growth of blood vessels that supply tumors and it speeds tumor growth. Whether long-term vaping can ... In reaction to nitric oxide, it hinders endothelial-dependent widening of blood vessels. It is associated with stroke, ... No published research is available on vaping and thrombosis, platelet reactivity, atherosclerosis, or blood vessel function. ...
Necrotizing vasculitis
Usually in children(age,4), it affects large, medium, and small vessels, prominently the coronary arteries. Associated with a ... Medium vessel vasculitis[edit]. These conditions are sometimes considered together with the small vessel vasculitides.[11] ... Small vessel vasculitis[edit]. There are several vasculitides that affect small vessels.[12] ... Seo P, Stone JH (December 2007). "Small-vessel and medium-vessel vasculitis". Arthritis Rheum. 57 (8): 1552-9. doi:10.1002/art. ...
Verification and validation
2008). "Drug-eluting or bare-metal stents forlarge coronary vessel stenting? The BASKET-PROVE (PROspective Validation ...
U wave
"The U wave is the momentum carried by the blood in the coronary arteries and blood vessels".[4][5][6] ... The U wave is the momentum carried by the blood in the coronary arteries and blood vessels. It is possible to take this ... which gradually increases high up in the coronary arteries and blood vessels. ... The interior of a blood vessel includes a near-wall layer of plasma (referred to as lubricant), the size of which strictly ...
Fibrin scaffold
In atherosclerosis, a severe disease in modern society, coronary blood vessels occlude. These vessels have to be freed and held ... Usually autologous vessels from the patient or synthetic polymer grafts are used for this purpose. Both options have ... Firstly there are only few autologous vessels available in a human body that might be of low quality, considering the health ... Unfortunately after certain time these vessels close again and have to be bypassed to allow for upkeep of circulation. ...
Angioplasty
Peripheral angioplasty refers to the use of a balloon to open a blood vessel outside the coronary arteries. It is most commonly ... A coronary angiogram (an X-ray with radio-opaque contrast in the coronary arteries) that shows the left coronary circulation. ... A coronary angioplasty is a therapeutic procedure to treat the stenotic (narrowed) coronary arteries of the heart found in ... A percutaneous coronary intervention is first performed. A PCI used with stable coronary artery disease reduces chest pain but ...
Angiography
Coronary angiography can visualize coronary artery stenosis, or narrowing of the blood vessel. The degree of stenosis can be ... Additionally, damage to blood vessels can occur at the site of puncture/injection, and anywhere along the vessel during passage ... which allows the interventional radiologist to evaluate the flow of the blood through a vessel or vessels. This technique " ... To detect coronary artery disease, a CT scan is more satisfactory than an MRI scan. The sensitivity and specificity between CT ...
List of African-American women in medicine
Pearl McBroom developed new ways of observing changes in coronary blood vessel tissue. Ernest Mae McCarroll in 1946 became the ...
Thrombus
This drug can be administered intravenously to dissolve blood clots in coronary vessels. However, streptokinase causes systemic ... Mural thrombi are thrombi that adhere to the wall of a blood vessel. They occur in large vessels such as the heart and aorta, ... A thrombus in a large blood vessel will decrease blood flow through that vessel (termed a mural thrombus). In a small blood ... Dissolution occurs when the fibrinolytic mechanisms break up the thrombus and blood flow is restored to the vessel. This may be ...
Rainier III, Prince of Monaco
... he was hospitalized with a coronary lesion and a damaged blood vessel.[14] In October he was again in hospital with a lung ...
Endomyocardial biopsy
However this method risked lung and coronary blood vessel damage, cardiac tamponade and arrythmias. EMB, sampling myocardium, ...
Melvin Judkins
He developed specialized pre-shaped catheters to reach the coronary vessels via the aorta. Today, they are commonly used and ... One of the Best of a Rare Breed: Melvin Paul Judkins, A Pioneer in Coronary Arteriography. Accessed May 1, 2020. Cowley MJ ( ... Judkins MP (1967). "Selective Coronary Arteriography". Radiology. 89 (5): 815-824. doi:10.1148/89.5.815. ISSN 0033-8419. PMID ... benefits of a newly fitted laboratory where he worked with colleagues to utilize these techniques to develop selective coronary ...
Systole
Notably, cardiac muscle perfusion through the heart's coronary vessels doesn't happen during ventricular systole; rather, it ... coordinated depolarisation and excitation-contraction coupling from the apex of the heart up to the roots of the great vessels ...
Norodom Sihanouk
... caused by the thickening of the coronary arteries and blood vessels.[296] In 1993, he was diagnosed with B cell lymphoma in the ...
Earl Wood
Shepherd, JT; Wood, EH (May 1959). "The role of vessel tone in pulmonary hypertension". Circulation. 19 (5): 641-645. doi: ... particularly in the coronary arteries, in man". Am J Cardiol. 32 (2): 144-150. doi:10.1016/s0002-9149(73)80112-2. PMID 4578631 ... Smith, HC; Sturm, RE; Wood, EH (August 1973). "Videodensitometric system for measurement of vessel blood flow, ...
Amylin family
CGRP induces vasodilatation in a variety of vessels, including the coronary, cerebral and systemic vasculature. Its abundance ...
Ventricular remodeling
Fibroblasts, collagen, the interstitium, and the coronary vessels to a lesser extent, also play a role. A common scenario for ...
King Faisal Hospital (Kigali)
... carrying out coronary angioplasty (opening narrowed or blocked blood vessels that supply blood to the heart); coronary stenting ... placing tube-shaped devices into the coronary arteries that supply blood to the heart to keep them open); as well as other ... interventions to correct blood flow, repair holes in the heart or locate blockages in blood vessels. In December 2020, the ...
Cardiology diagnostic tests and procedures
Cardiac imaging techniques include coronary catheterization, echocardiogram, intravascular ultrasound, retinal vessel analysis ... High frequency analysis of the QRS complex may be useful for detection of coronary artery disease during an exercise stress ... to assess the evolution of coronary artery disease and evidence of existing damage. A great many more physiologic markers ... and the coronary calcium scan. Cardiology Reference ranges for common blood tests Medical technologist Gerald, F; Philip, A; ...
Endarterectomy
Coronary endarterectomy involves removing atheroma from the wall of blocked blood vessels (coronary) supplying the heart muscle ... "Long-term survival from 801 adjunctive coronary endarterectomies in diffuse coronary artery disease". European Journal of ... The concept was first introduced by Bailey in the 1950s prior to the advent of coronary artery bypass surgery to help patients ... It is still used today when coronary artery bypass surgery proves difficult. Livesay in Texas and Nair in Leeds have published ...
Hybrid cardiac surgery
Integrating this therapy with percutaneous coronary angioplasty (hybrid procedure) offers multi-vessel revascularization ... Thus hybrid coronary revascularization and MIDCAB (minimally invasive direct coronary artery bypass surgery) have been ... For people who undergo coronary artery bypass grafting, coronary imaging (completion angiography) for the routine evaluation of ... Surgical bypass grafting and percutaneous coronary artery revascularization are traditionally considered isolated options. A ...
Internal thoracic artery
The internal thoracic artery is the cardiac surgeon's blood vessel of choice for coronary artery bypass grafting. The left ITA ... when grafted to the left anterior descending coronary artery, generally the most important vessel, clinically, to revascularize ... texheartsurgeons.com Drawing of the heart with a SVG to the right coronary artery (RCA) and a LITA graft to the LAD - ... Vessels of the breast", Visceral Vascular Manipulations, Oxford: Churchill Livingstone, pp. 121-132, doi:10.1016/b978-0-7020- ...
Prolene
It is used on both small vessels such as coronary artery bypasses and large vessels including the aorta. It is used in ...
Langendorff heart
... forcing the solution into the coronary vessels, which normally supply the heart tissue with blood. This feeds nutrients and ... In the Langendorff preparation, the heart is removed from the animal's body, severing the blood vessels; it is then perfused in ... The Langendorff heart preparation-Reappraisal of its role as a research and teaching model for coronary vasoactive drugs, K.J. ...
Glossary of medicine
Coronary arteries - are the blood vessels (arteries) of coronary circulation, which transports oxygenated blood to the actual ... Blood vessel - The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout ... "Blood Vessels - Heart and Blood Vessel Disorders - Merck Manuals Consumer Version". Merck Manuals Consumer Version. Retrieved ... is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and ...
Collateralization
... the pressure gradient between the segment of the coronary vessel distal to the occlusion and the incipient collateral vessel ... also vessel collateralization and blood vessel collateralization, is the growth of a blood vessel or several blood vessels that ... Coronary collateralization exists latently in the normal heart. Microscopic collateral vessels of the heart undergo a process ... Coronary collateralization: determinants of adequate distal vessel filling after arterial occlusion. Coron Artery Dis. 2002 May ...
Elastina - Wikipédia, a enciclopédia livre
blood vessel remodeling. •skeletal muscle tissue development. •respiratory gaseous exchange. •blood circulation. •cell ... 2009). «Integrative predictive model of coronary artery calcification in atherosclerosis». Circulation. 120 (24): 2448-54. PMC ...
Radiography
... is used to view the vessels under X-ray. Angiography is used to find aneurysms, leaks, blockages (thromboses), new vessel ... Since liquid blood and the vessels are not very dense, a contrast with high density (like the large iodine atoms) ...
Music therapy
Others suggest that music serves as a sort of mediator for social interactions, providing a vessel through which to interact ... and blood pressure in those with coronary heart disease (CHD).[37] ... "Music for stress and anxiety reduction in coronary heart disease patients". The Cochrane Database of Systematic Reviews (12): ...
Intermittent claudication
Cardiovascular disease (vessels) (I70-I99, 440-456). Arteries, arterioles. and capillaries. Inflammation. *Arteritis *Aortitis ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ...
Fibrinolysis
t-PA is released into the blood very slowly by the damaged endothelium of the blood vessels, such that, after several days ( ... They are given following a heart attack to dissolve the thrombus blocking the coronary artery; experimentally after a stroke to ...
Fenoldopam
... and coronary arteries.[8] to cause a reduction in systemic vascular resistance. Fenoldopam has a rapid onset of action (4 ... Blood Vessels. 26 (2): 119-27. PMID 2474340.. ...
Julie Campbell (vascular biologist)
Campbell has been developing a technique to grown the artificial blood vessel in the body cavity of the person it will be ... This process is undergoing pre-clinical trials in humans and may be used to treat patients suffering coronary heart disease, ... Campbell has won worldwide acclaim for her ground-breaking research into the development of blood vessels naturally within a ... This 'Grow Your Own Arteries' technique is helping patients survive coronary heart disease, renal failure and other life- ...
Hypertensive kidney disease
The tissue hardens and thickens which is known as nephrosclerosis.[2] The narrowing of the blood vessels means less blood is ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... High blood pressure in the long term can damage the endothelium, commonly known as the blood vessel lining. This leads to a ... Glomerulosclerosis is often present, either focally or globally, which is characterized by hardening of the vessel walls. Also ...
Radiation therapy
They are often due to damage of blood vessels and connective tissue cells. Many late effects are reduced by fractionating ... coronary artery disease, heart arrhythmia and peripheral artery disease. Radiation-induced fibrosis, vascular cell damage and ... for example when the tumor is wrapped around a vulnerable structure such as the spinal cord or a major organ or blood vessel.[ ... heat therapy which dilates blood vessels to the tumor site), blood substitutes that carry increased oxygen, hypoxic cell ...
Angioscopy
Coronary artery angioscopy, which first was used to reveal the presence of a blood clot in the coronary arteries of patients ... Angioscopy is a medical technique for visualizing the interior of blood vessels. In this technique, a flexible fiberoptic ... Forrester JS, Litvack F, Grundfest W, Hickey A (1987). "A perspective of coronary disease seen through the arteries of living ...
Common ostrich
The coronary arteries start in the right and left aortic sinus and provide blood to the heart muscle in a similar fashion to ... Common ostriches develop via Intussusceptive angiogenesis, a mechanism of blood vessel formation, characterizing many organs.[ ... It then moves along the coronary groove and continues on into the tissue as interventricular branches toward the apex of the ... The deep branches of the coronary arteries found within the heart tissue are small and supply the interventricular and right ...
Vitamin D toxicity
The levels of the active form of vitamin D, calcitriol, are inversely correlated with coronary calcification.[23] Moreover, the ... Heart and Vessels. 25 (1): 1-6. doi:10.1007/s00380-009-1151-4. PMID 20091391.. ... in the association of coronary calcified plaque in that there is less calcified atherosclerotic plaque in the coronary arteries ... "Active serum vitamin D levels are inversely correlated with coronary calcification". Circulation. 96 (6): 1755-60. doi:10.1161/ ...
Heart valve
venae cavae, coronary sinus) → right atrium (atrial appendage, fossa ovalis, limbus of fossa ovalis, crista terminalis, valve ... Heart valves separate the atria from the ventricles, or the ventricles from a blood vessel. Heart valves are situated around ... As they mature, they rotate slightly as the outward vessels spiral, and move slightly closer to the heart.[8] ... The heart also has a coronary sinus valve, and an inferior vena cava valve, not discussed here. ...
Hypertensive emergency
Coronary perfusion pressures are decreased by these factors, which also increase myocardial oxygen consumption, possibly ... Cerebral autoregulation is the ability of the blood vessels in the brain to maintain a constant blood flow. People who suffer ... Excessive reduction in blood pressure can precipitate coronary, cerebral, or renal ischemia and, possibly, infarction. ... preexisting diabetes or coronary artery disease, mental illness, and sedentary lifestyle.[3] Several studies have concluded ...
ഫലകം:Cardiac procedures - വിക്കിപീഡിയ
Cardiac vessels. CHD. Angioplasty. Bypass/Coronary artery bypass MIDCAB. Off-pump CAB. TECAB. Coronary stent. Bare-metal stent ... shunt from blood vessel to blood vessel. systemic circulation to pulmonary artery shunt Blalock-Taussig shunt. SVC to the right ... shunt from heart chamber to blood vessel. atrium to pulmonary artery Fontan procedure. left ventricle to aorta Rastelli ... for transposition of great vessels Jatene procedure. Mustard procedure. for univentricular defect Norwood procedure. Kawashima ...
Hemoglobin
Padmanaban, P.; Toora, B. (2011). "Hemoglobin: Emerging marker in stable coronary artery disease". Chronicles of Young ... especially the delicate blood filtering vessels of the kidneys, causing kidney damage. Iron is removed from heme and salvaged ... A recent study done in Pondicherry, India, shows its importance in coronary artery disease.[83] ... degraded hemoglobin protein or hemoglobin that has been released from the blood cells too rapidly can clog small blood vessels ...
ധമനികൾ - വിക്കിപീഡിയ
http://biology.about.com/od/anatomy/ss/Coronary-Arteries.htm *↑ http://www.bookrags.com/research/aortic-arch-wap/ ... http://www.fi.edu/learn/heart/vessels/arteries.html. *http://www.1911encyclopedia.org/Arteries ...
Anastomosis
An anastomosis is the connection of two normally divergent structures.[2] It refers to connections between blood vessels or ... coronary arteries and cortical branch of cerebral arteries). Anastomoses also form alternative routes around capillary beds in ... An example of surgical anastomosis occurs when a segment of intestine, blood vessel, or any other structure are connected ... such as between blood vessels, leaf veins, or streams. Such a connection may be normal (such as the foramen ovale in a fetus's ...
Atrial fibrillation
In men, coronary disease is more frequent, while in women, high systolic blood pressure and valvular heart disease are more ... Also, people with a higher risk of AF, e.g., people with pre-operative hypertension, more than three vessels grafted, or ... High blood pressure, valvular heart disease, coronary artery disease, cardiomyopathy, congenital heart disease, COPD, obesity, ... Cardiovascular factors known to be associated with the development of AF include high blood pressure, coronary artery disease, ...
Torcetrapib
Phase III Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart Disease ...
Calcium channel blocker
CCBs are particularly effective against large vessel stiffness, one of the common causes of elevated systolic blood pressure in ... reduce myocardial oxygen demand and reverse coronary vasospasm, and are often used to treat angina. They have minimal ... Since lymphatic drainage relies on contraction of the skeletal smooth muscle inside the lymphatic vessel[18] supported by ...
Secondary hypertension
... or small blood vessels in the kidneys.[6][7][8] ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. ...
Aorta
Right and left coronary arteries.. Arch of aorta (supra-aortic vessels): Brachiocephalic trunk. Left common carotid artery. ... For this reason the left, right and posterior aortic sinuses are also called left-coronary, right-coronary and non-coronary ... The aorta ends by dividing into two major blood vessels, the common iliac arteries and a smaller midline vessel, the median ... Combination of coronary sinus, superior vena cava and inferior vena cava. Supplies. The systemic circulation. (entire body with ...
Sepsis
Increased permeability of the lung vessels causes leaking of fluids into alveoli, which results in pulmonary edema and acute ... It is the second-leading cause of death in non-coronary intensive care unit (ICU) and the tenth-most-common cause of death ... a deficiency of chemicals that constrict blood vessels such as vasopressin, and activation of ATP-sensitive potassium channels. ... and interleukin 6 may activate procoagulation factors in the cells lining blood vessels, leading to endothelial damage. The ...
Neil Armstrong
"Navy Announces Research Vessel to be Named in Honor of Neil Armstrong". United States Navy. September 24, 2012. Archived from ... Armstrong underwent bypass surgery on August 7, 2012, to relieve coronary artery disease.[210] Although he was reportedly ... Navy announced that the first Armstrong-class vessel would be named RV Neil Armstrong. Delivered to the Navy on September 23, ...
Vertebral artery dissection
Firstly, the flow through the blood vessel may be disrupted due to the accumulation of blood under the vessel wall, leading to ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... the small blood vessels that supply the outer layer of larger blood vessels.[1][2] Various theories exist as to whether people ... inside the blood vessel). This may be performed to allow the blood to flow through a severely narrowed vessel, or to seal off ...
Heart valve
... s separate the atria from the ventricles, or the ventricles from a blood vessel. Heart valves are situated around ... The heart also has a coronary sinus valve, and a inferior vena cava valve, not discussed here. ... As they mature, they rotate slightly as the outward vessels spiral, and move slightly closer to the heart.[8] ...
Intracranial aneurysm
A catheter is inserted into a blood vessel, typically the femoral artery, and passed through blood vessels into the cerebral ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... When a patient has an aneurysm involving a blood vessel or a tumor at the base of the skull wrapping around a blood vessel, ... where small communicating vessels link the main cerebral vessels. These areas are particularly susceptible to saccular ...
Rofecoxib
Heart and blood vessels[edit]. VIGOR study and publishing controversy[edit]. The VIGOR (Vioxx GI Outcomes Research) study, ... or coronary artery bypass). ... 2.1 Heart and blood vessels *2.1.1 VIGOR study and publishing ... Merck has stated that there was no effect on prostacyclin production in blood vessels in animal testing.[13] Corey speculated ...
Blood Vessels and Coronary Arteries - Our Heart and Cardiovascular System | Coursera
The left coronary artery and the right coronary artery.. The left coronary artery begins with the left main stem, which then ... Blood Vessels and Coronary Arteries. To view this video please enable JavaScript, and consider upgrading to a web browser that ... of blood vessels, the architecture of the blood vessels and the histology. ... All of our vessels basically are built in three layers.. And if we have a close look at those layers, we see in the innermost ...
Rcadia COR Analyzer System Receives Expanded FDA Clearance to Rule Out Coronary Artery Disease in Coronary Branch Vessels
System to assess coronary branch vessels in addition to main coronary arteries in patients with suspected coronary artery ... Rcadia COR Analyzer System Receives Expanded FDA Clearance to Rule Out Coronary Artery Disease in Coronary Branch Vessels. News ... Rcadia COR Analyzer System Receives Expanded FDA Clearance to Rule Out Coronary Artery Disease in Coronary Branch Vessels ... provides a high negative predictive value for the absence of coronary disease in branch vessels as well as the major coronary ...
Successful Implantation of a Coronary Stent Graft in a Peripheral Vessel
Here we present for the first time a case reporting on the placement of coronary stent graft in a peripheral vessel for the ... angiologists or radiologists may consider such an option for complication management after injury of smaller vessels during ... Successful Implantation of a Coronary Stent Graft in a Peripheral Vessel. Alexander Hess. ,1 Britta Vogel. ,1 Benedikt Kohler. ... Here we present for the first time a case reporting on the placement of coronary stent graft in a peripheral vessel for the ...
Patente US6443158 - Percutaneous coronary artery bypass through a venous vessel - Google Patentes
Blood flow is provided to a distal portion of the artery through an adjacent venous vessel so that blood can be provided to ... The bypass system couples a restricted artery to a venous vessel distal of a restriction to provide blood flow through the ... A bypass system for bypassing a restriction in a parent vessel of a mammal to provide blood flow past the restriction. ... Coronary artery 16 includes restriction 22. Veins 20 are arranged adjacent to coronary arteries 16. Coronary arteries 16 carry ...
Thinking Outside the Vessel: New Gel to Heal Coronary Arteries | Medgadget
... is working on a radical new theory for the treatment of damaged coronary arteries. He ... Thinking Outside the Vessel: New Gel to Heal Coronary Arteries. June 26th, 2007 Josh Umbehr Cardiology ... The vessels can also be connected with a plastic tube, or shunt.. However, the surgical trauma can damage the endothelium and ... The vessel walls then scar and thicken, leading to restenosis.. The Pervasis product contains endothelial cells grown from ...
Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI) - Study Results -...
Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI) (RIVER-PCI). The safety and ... design and rationale of the Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (RIVER- ... Effects of Ranolazine on Angina and Quality of Life After Percutaneous Coronary Intervention With Incomplete Revascularization ... Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): a multicentre, ...
Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI) - Tabular View -...
... stenoses in one or more coronary arteries with reference vessel diameter of at least 2.0 mm, whether in the target vessel or in ... Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI) (RIVER-PCI). The safety and ... Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI). Official Title ICMJE A Phase ... a non-target vessel regardless of the presence or absence of coronary collaterals. In the case of a participant post-coronary ...
Noninvasive Coronary Vessel Wall and Plaque Imaging With Magnetic Resonance Imaging | Circulation
Coronary vessel wall images were readily acquired in all subjects. Both coronary vessel wall thickness (1.5±0.2 versus 1.0±0.2 ... measurements of coronary wall thickness suggests that MR coronary vessel wall imaging is able to assess coronary vessel wall ... free-breathing coronary vessel wall imaging approach using a dual IR TSE sequence and to compare coronary vessel wall and lumen ... small coronary vessel wall thickness, and low contrast-to-noise ratios (CNRs) between the coronary vessel wall and the ...
Three-vessel coronary artery disease with multi-vessel proximal aneurysms.
At coronary angiography, left anterior descending coronary artery was occluded with distal perfusion by collateral flow, and ... 6619704 - Coronary angiographic assessment of left posterior hemiblock.. 20443654 - Three-vessel coronary artery disease with ... Coronary Aneurysm / complications*, diagnosis*, therapy. Coronary Angiography. Coronary Artery Disease / complications*, ... right coronary artery with diffuse coronary atherosclerosis were present. Coronary thrombosis was also present into LCX ...
Association between erectile dysfunction and coronary artery disease. Role of coronary clinical presentation and extent of...
... acute coronary syndrome (ACS) vs. chronic coronary syndrome (CCS), and extent of vessel involvement (single vs. multi-vessel ... Role of coronary clinical presentation and extent of coronary vessels involvement: the COBRA trial.. Montorsi P1, Ravagnani PM ... single-vessel (OR=2.53; 95% CI, 1.43-4.51; P=0.0002), and CCS vs. ACS (OR=2.32; 95% CI, 1.22-4.41; P=0.01) were independent ... 285 patients with CAD divided into three age-matched groups: group 1 (G1, n=95), ACS and one-vessel disease (1-VD); group 2 (G2 ...
Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans. - PubMed - NCBI
Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans.. Lerman A1, Burnett JC Jr, ... Long-term oral L-arginine supplementation for 6 months in humans improves coronary small-vessel endothelial function in ... Twenty-six patients without significant coronary artery disease on coronary angiography and intravascular ultrasound were ... reverses coronary endothelial dysfunction to acetylcholine in humans with nonobstructive coronary artery disease. ...
Single Coronary Vessel Disease: Disease Bioinformatics: Novus Biologicals
Learn more about Single Coronary Vessel Disease from related diseases, pathways, genes and PTMs with the Novus Bioinformatics ... Single Coronary Vessel Disease: Disease Bioinformatics. Single Coronary Vessel Disease is the progression of atherosclerosis in ... Single Coronary Vessel Disease is also known as Single Vessel Coronary Artery Disease. ... Single Coronary Vessel Disease has been studied in relation to diseases such as: *Coronary Artery Disease ...
Clinical Progression of Incidental, Asymptomatic Lesions Discovered During Culprit Vessel Coronary Intervention | Circulation
Coronary Heart Disease. Clinical Progression of Incidental, Asymptomatic Lesions Discovered During Culprit Vessel Coronary ... B, Progression of disease in nonculprit vessel. Mild disease is observed in mid right coronary artery (middle left) at the time ... A, Progression of disease in nonculprit vessel resulting in MI (top left). Distal right coronary artery lesion (solid arrows), ... Clinical Progression of Incidental, Asymptomatic Lesions Discovered During Culprit Vessel Coronary Intervention ...
Proepicardial Origin of Developing Coronary Vessels | Revista Española de Cardiología (English Edition)
Identifying Vulnerable Plaques in Blood Vessels of the Heart Using a New Imaging Technique | Clinical Research Trial Listing (...
Identifying Vulnerable Plaques in Blood Vessels of the Heart Using a New Imaging Technique ... Many people who have coronary artery disease and are at risk of having a heart attack undergo angioplasty, a procedure that ... Identifying Vulnerable Plaques in Blood Vessels of the Heart Using a New Imaging Technique Brief description of study. ... An OFDI is a new type of catheter that takes more detailed pictures of blood vessel walls and plaques. The additional detail ...
Frontiers | GWAS Reveal Targets in Vessel Wall Pathways to Treat Coronary Artery Disease | Cardiovascular Medicine
In this mini-review, we highlight the most recently identified loci that have predicted roles in the vessel wall and provide ... In this mini-review, we highlight the most recently identified loci that have predicted roles in the vessel wall and provide ... the majority of the annotated genes at these loci encode for proteins involved in vessel wall function with no known drugs ... the majority of the annotated genes at these loci encode for proteins involved in vessel wall function with no known drugs ...
Spontaneous triple vessel coronary artery dissection in a patient with effort angina | Heart
Selective coronary angiography revealed SCAD involving all three vessels. Right coronary angiogram showed linear dissection ... Spontaneous triple vessel coronary artery dissection in a patient with effort angina ... Spontaneous triple vessel coronary artery dissection in a patient with effort angina ... spontaneous three vessel coronary dissection associated with typical effort angina has never been reported. This case ...
Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans
Long-term oral L-arginine supplementation for 6 months in humans improves coronary small-vessel endothelial function in ... Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans Circulation. 1998 Jun 2;97( ... Conclusions: Long-term oral L-arginine supplementation for 6 months in humans improves coronary small-vessel endothelial ... Methods and results: Twenty-six patients without significant coronary artery disease on coronary angiography and intravascular ...
The Heart: anatomy, blood, cardiac, coronary, en, heart, human, science, supply, vessels | Glogster EDU - Interactive...
Abbott Receives U.S. FDA Approval for XIENCE nano™ to Treat Coronary Artery Disease in Small Vessels | FiercePharma
Everolimus Eluting Coronary Stent System for the treatment of coronary artery disease in small vessels. XIENCE nano, which is ... Everolimus has been shown to inhibit in-stent neointimal growth in the coronary vessels following stent implantation, due to ... Abbott Receives U.S. FDA Approval for XIENCE nano™ to Treat Coronary Artery Disease in Small Vessels ... "The treatment of small vessels is often complex and associated with higher rates of complications compared to larger vessels," ...
Clinical and angiographic outcome of elective stent implantation in small coronary vessels: an analysis of the BENESTENT trial.
We examined the influence of vessel size using an intention-to-treat approach in 259 patients who underwent stent implantation ... Blood Vessel Prosthesis Implantation*. Coronary Angiography. Coronary Disease / etiology, surgery*. Coronary Vessels / ... In the stented population, smaller vessel size was associated with a higher stent:vessel ratio, a greater relative gain and a ... 9231549 - Coronary artery stenting in acute myocardial infarction.. 19205549 - Left main coronary artery stenosis treatment ...
Binding of [3H]-5-hydroxytryptamine to human coronary artery and bypass graft vessels
... Dahm, Peter L. ; Bodelsson, Mikael LU ; ... The aim of the present study was to localise the 5-HT receptors within the vessel wall. METHODS: Epicardial coronary arteries ... The aim of the present study was to localise the 5-HT receptors within the vessel wall. METHODS: Epicardial coronary arteries ... The aim of the present study was to localise the 5-HT receptors within the vessel wall. METHODS: Epicardial coronary arteries ...
Percutaneous Intervention in Small-Vessel Coronary Disease | JACC: Cardiovascular Interventions
Presence of the Metabolic Syndrome Does Not Impair Coronary Collateral Vessel Formation in Patients With Documented Coronary...
Presence of the Metabolic Syndrome Does Not Impair Coronary Collateral Vessel Formation in Patients With Documented Coronary ... Presence of the Metabolic Syndrome Does Not Impair Coronary Collateral Vessel Formation in Patients With Documented Coronary ... Presence of the Metabolic Syndrome Does Not Impair Coronary Collateral Vessel Formation in Patients With Documented Coronary ... Presence of the Metabolic Syndrome Does Not Impair Coronary Collateral Vessel Formation in Patients With Documented Coronary ...
Table 2 | Predictors for New Native-Vessel Occlusion in Patients with Prior Coronary Bypass Surgery: A Single-Center...
Non-Coronary Vascular Stents: Mesenteric Vessels - Find-A-Code Spotlight Articles
Mesenteric vessels: This includes Acute mesenteric ischemia Chronic mesenteric ischemia Mesenteric thrombosis Dissection or any ... resulting in gastrointestinal symptoms Stenting of the mesenteric vessels is covered only when angioplasty of the vessels would ... Non-Coronary Vascular Stents: Mesenteric Vessels. by Find-A-Code. January 29th, 2018 ... Stenting of the mesenteric vessels is covered only when angioplasty of the vessels would not suffice and after the patient has ...
Coronary blood vessels | definition of Coronary blood vessels by Medical dictionary
What is Coronary blood vessels? Meaning of Coronary blood vessels medical term. What does Coronary blood vessels mean? ... Looking for online definition of Coronary blood vessels in the Medical Dictionary? Coronary blood vessels explanation free. ... Coronary blood vessels. Coronary blood vessels. The arteries and veins that supply blood to the heart muscle. ... By carrying this gene vector into the coronary circulation, it should help the cells that form coronary blood vessels grow.. ...
Long-term outcomes of percutaneous coronary intervention in grafts and native vessels in coronary artery bypass grafting...
Evidence on how to choose target vessels of percutan... ... Long-term outcomes of percutaneous coronary intervention in ... grafts and native vessels in coronary artery bypass grafting patients with diabetes mellitus. J Thorac Dis. 2019 Nov;11(11): ... Long-term outcomes of percutaneous coronary intervention in grafts and native vessels in coronary artery bypass grafting ... Long-term outcomes of percutaneous coronary intervention in grafts and native vessels in coronary artery bypass grafting ...
FURTHER OBSERVATIONS ON THE ACTION OF DRUGS ON THE CALIBER OF CORONARY VESSELS PAPAVERINE HYDROCHLORIDE, DIGITALIS DERIVATIVES,...
3. Calcium gluconate, in contrast with the chloride salt which is a powerful dilator of the coronary vessels, does not cause ... FURTHER OBSERVATIONS ON THE ACTION OF DRUGS ON THE CALIBER OF CORONARY VESSELS PAPAVERINE HYDROCHLORIDE, DIGITALIS DERIVATIVES ... FURTHER OBSERVATIONS ON THE ACTION OF DRUGS ON THE CALIBER OF CORONARY VESSELS PAPAVERINE HYDROCHLORIDE, DIGITALIS DERIVATIVES ... FURTHER OBSERVATIONS ON THE ACTION OF DRUGS ON THE CALIBER OF CORONARY VESSELS PAPAVERINE HYDROCHLORIDE, DIGITALIS DERIVATIVES ...
Association between erectile dysfunction and coronary artery disease. Role of coronary clinical presentation and extent of...
ED prevalence differs across subsets of patients with CAD and is related to coronary clinical presentation and extent of CAD. ... acute coronary syndrome (ACS) vs. chronic coronary syndrome (CCS), and extent of vessel involvement (single vs. multi-vessel ... Role of coronary clinical presentation and extent of coronary vessels involvement: the COBRA trial Eur Heart J. 2006 Nov;27(22 ... single-vessel (OR=2.53; 95% CI, 1.43-4.51; P=0.0002), and CCS vs. ACS (OR=2.32; 95% CI, 1.22-4.41; P=0.01) were independent ...
ArteriesDiseaseRight coronaAtherosclerosisStenosisBlood vesselRevascularizationIntravascular ultrasoundGraftCardiacLesionsAngioplastyStentsProximalAtheroscleroticInterventionsAngiographicUnderwentClinicalCirculationLesionDiameterConclusionsMyocardial ischemiaCardiovascularOcclusionAortaPlaqueVeinsEpicardialEndothelial functionArterialSmall vesselsCollateralsElective
Arteries62
- The second lecture displays the various types of blood vessels and arteries. (coursera.org)
- which is about blood vessels and coronary arteries. (coursera.org)
- NEWTON, Mass. , Feb. 9, 2011 /PRNewswire/ -- Rcadia Medical Imaging announced today that it has received FDA 510(k) marketing clearance for an enhanced version of its COR Analyzer® System to assess coronary branch vessels in addition to main coronary arteries in patients with suspected coronary artery disease (CAD). (prnewswire.com)
- The clearance is the third for the COR Analyzer System, a unique clinical decision support tool that automatically detects significant (50 percent and over) stenotic lesions in coronary arteries from Coronary CT Angiography (cCTA) studies. (prnewswire.com)
- The study, published (online) in Academic Radiology in January 2011 by researchers at Thomas Jefferson University , demonstrated that the 'COR Analyzer provides a high negative predictive value for the absence of coronary disease in branch vessels as well as the major coronary arteries. (prnewswire.com)
- Harvard-MIT professor and biomedical engineer Elazer Edelman, is working on a radical new theory for the treatment of damaged coronary arteries. (medgadget.com)
- Control group (C, n=95) was composed of patients with suspected CAD who were found to have entirely normal coronary arteries by angiography. (nih.gov)
- METHODS: Epicardial coronary arteries obtained from patients undergoing cardiac transplantation, internal mammary arteries from heart donors and saphenous veins from patients undergoing coronary bypass surgery, were sectioned and incubated with [3H]-5-HT for in vitro receptor autoradiography. (lu.se)
- Reactivity of canine isolated epicardial collateral coronary arteries. (ahajournals.org)
- To study the relation between structure and vascular reactivity in mature coronary collateral arteries, we prepared 17 dogs with a casein occluder near the origin of the circumflex coronary artery. (ahajournals.org)
- At least 24 weeks later, we examined the reactivity of surface collateral arteries (approximately 500 micron i.d.) to a range of constrictor and dilator agents and compared them with normal left anterior descending coronary arteries of similar size branching away from the collateral zone. (ahajournals.org)
- Pairs of normal and collateral arteries 2 mm long were mounted in a double-vessel myograph for isometric force recording. (ahajournals.org)
- In each case, the collateral vessels contracted to approximately half the force generated by the normal arteries. (ahajournals.org)
- When partially contracted by K+ (25-30 mM), the collateral vessels had a greater range of relaxation and similar sensitivity to acetylcholine, sodium nitroprusside, and cromakalim compared with normal arteries. (ahajournals.org)
- Coronary collateral arteries are thus compromised flow conduits that may play a role in vasospastic angina. (ahajournals.org)
- The coronary arteries , which branch off the aorta just after it leaves the heart, deliver this blood. (merckmanuals.com)
- Coronary artery disease that narrows one or more of these arteries can block blood flow, causing chest pain (angina) or an acute coronary syndrome (see also Overview of Coronary Artery Disease ). (merckmanuals.com)
- group 2, February 1988 to March 1990) and vessel type (native arteries versus bypass grafts). (eur.nl)
- We sought to investigate the clinical outcomes after the treatment of Magic Touch Sirolimus Coated Balloon (SCB, Concept Medical Research Pvt Ltd, Surat, India) in patients with lesions located in small coronary arteries. (onlinejacc.org)
- Coronary arteries were visualized by a T2-prepared steady state free precession technique. (onlinejacc.org)
- RSNA 2012 Coronary Arteries: Native Vessel Disease Pt. (ctisus.com)
- The reporting system of representing stenosis area on the coronary arteries is developed. (nii.ac.jp)
- The authors previously reported that in rabbits, isoflurane exhibited a heterogeneous vasomotor effect, constricting small resistance coronary arteries and dilating larger conductance arteries. (asahq.org)
- The novelty of isoflurane-induced constriction of small coronary arteries raised the question of whether the finding depended on the unique experimental setup or species used. (asahq.org)
- Methods: Thirty-six large coronary arteries (262 plus/minus 23 micro meter) and 42 small coronary arteries (99 plus/minus 15 micro meter) from 31 Wistar rats were isolated. (asahq.org)
- Results: Isoflurane constricted predilated or untreated small coronary arteries, but had no effect on preconstricted small arteries. (asahq.org)
- Isoflurane dilated large coronary arteries, with the preconstricted vessels dilating the most. (asahq.org)
- In contrast, halothane dilated both the small and large coronary arteries to a similar extent. (asahq.org)
- Conclusions: Whereas isoflurane has a heterogeneous vasomotor effect in rat coronary arteries, constricting the small vessels and dilating the large ones, halothane dilates both the small and large arteries. (asahq.org)
- Recently, however, we reported that in rabbits, isoflurane has a heterogeneous vasomotor effect on coronary arteries in vitro, constricting small subepicardial resistance arteries and dilating larger epicardial conductance arteries. (asahq.org)
- 3 The novelty of isoflurane-induced vasoconstriction of small coronary arteries raised the question of whether the finding was dependent on the unique experimental setup and/or species used and what vasomotor effect other volatile anesthetics might exert. (asahq.org)
- RESULTS:Processing of the myocardium's thermographic images and the results of heat spreading modeling make it possible to single out the temperature profiles of the visible myocardium zones and to establish the presence of coronary arteries in them. (iospress.com)
- the parts of the blood vessels are veins,arteries and capillaries arteries-are blood vessels that carry blood away from the heart. (answers.com)
- veins-carry blood back to the heart capillaries-are the tiny blood vessels that connects the arteries to the veins. (answers.com)
- These are arteries,the veins, and the capillaries.Arteries are thick walled and elastic blood vessels. (answers.com)
- small blood vessels that branch from the arteries and transport blood from the heart to the body tissues. (answers.com)
- The coronary arteries or vessels deliver blood to the heart muscle, providing a continuous supply of oxygen and nutrients needed for it to stay healthy and function normally. (answers.com)
- Arteries are the vessels that move blood into and out of the heart. (answers.com)
- The coronary vessels include the coronary arteries and coronary veins which nourish the heart. (lifemapsc.com)
- Capillaries , which join the arteries and veins, and the lymphatic vessels are not shown. (rug.nl)
- Malformations of CORONARY VESSELS, either arteries or veins. (selfdecode.com)
- When the contrast agent was injected, we were able to watch on the screen as it went through the coronary arteries. (blogspot.com)
- Medical University Innsbruck is conducting an prospective-observational, explorative single-centre cohort study in 55 participants in order to to examine the atherosclerosis progression in coronary arteries compared to peripheral vessels (carotids, femoral arteries). (happidoc.com)
- Atherosclerotic alterations in peripheral vessels (IMT, plaque volume, plaque morphology) will be measured with ultrasound (IMT measurements and 3D quantitative plaque volumetry), whereas atherosclerotic alterations in coronary arteries will be tested with cardiac computertomography (CT) (coronary artery calcium score, calcium volume score, plaque morphology). (happidoc.com)
- The primary endpoint of the planned study will be the correlation of the atherosclerotic progression between coronary arteries and peripheral arteries (carotids, femoral arteries). (happidoc.com)
- Also plaque morphology will be compared between coronary arteries and peripheral vessels. (happidoc.com)
- OBJECTIVE: We used intravascular ultrasound (IVUS) and virtual histology (VH) to assess the differences of plaque burden and composition between target coronary arteries containing the culprit lesion and non-target coronary arteries. (unibas.ch)
- There is a strong correlation of plaque composition between target and non-target coronary arteries. (unibas.ch)
- The heart receives its own supply of blood from the coronary arteries. (clevelandclinic.org)
- Two major coronary arteries branch off from the aorta near the point where the aorta and the left ventricle meet. (clevelandclinic.org)
- When the coronary arteries narrow to the point that blood flow to the heart muscle is limited (coronary artery disease), collateral vessels may enlarge and become active. (clevelandclinic.org)
- The coronary blood vessels include both arteries and veins, according to the Cleveland Clinic. (reference.com)
- As stated by Stanford Hospital, coronary arteries supply oxy. (reference.com)
- How Many Coronary Arteries Does a Human Have? (reference.com)
- The human body contains three main coronary arteries that provide oxygen and nutrients to the heart and multiple smaller coronary arteries. (reference.com)
- There is evidence from Harrison and Bates (1993) (Circulation vol 87, p 1461) that GTN dilates larger coronary arteries better than smaller ones. (medchrome.com)
- This would have little effect on the overall resistance of, and flow through, through normal coronary arteries (since resistance mainly resides in the arterioles which are not dilated), but could increase flow through coronary collaterals, thereby improving flow in stenosed coronary arteries. (medchrome.com)
- The aim of this study was to assess the factors associated with the atherosclerotic involvement of small coronary arteries as compared to large vessel disease, in patients with type 2 diabetes mellitus undergoing percutaneous stent coronary angioplasty. (sciendo.com)
- Bioabsorbable stents were implanted in 57% of coronary arteries suffering from small vessel disease, compared to 4% in the rest of the coronary arteries (p = 0.005). (sciendo.com)
- The location of the atherosclerotic process at the level of the small coronary arteries is associated with a significantly higher Calcium Score at the level of the coronary tree, and with a higher rate of bioabsorbable stent implantation. (sciendo.com)
- Occlusion of the biggest coronary arteries on account of atherosclerosis and blood clotting is often handled by catheter-mediated reopening. (dopewallpapers.com)
- The internal, common and external carotid arteries are carefully identified, controlled with vessel loops, and clamped. (wikipedia.org)
Disease111
- In Switzerland alone, the risk to develop a coronary heart disease during life time is around 25% for men and 18% for women. (coursera.org)
- The investigators noted that the 'high negative predictive value will be most useful in a population with a low prevalence of coronary disease - such as the emergency room chest pain population - where the COR Analyzer might be used to facilitate the rapid discharge of a majority of patients who have normal coronary CTA studies during all hours of the day or night. (prnewswire.com)
- The company's first FDA-cleared product, the COR Analyzer® System, provides fully automated, real-time analysis of Coronary CT angiography to enable the practical application of cCTA in detecting significant coronary artery disease. (prnewswire.com)
- Methods and Results -Ten subjects, including 5 healthy adult volunteers (aged 35±17 years, range 19 to 56 years) and 5 patients (aged 60±4 years, range 56 to 66 years) with x-ray-confirmed coronary artery disease (CAD), were studied with a T2-weighted, dual-inversion, fast spin-echo MR sequence. (ahajournals.org)
- Three-vessel coronary artery disease with multi-vessel proximal aneurysms. (biomedsearch.com)
- Association between erectile dysfunction and coronary artery disease. (nih.gov)
- To investigate the prevalence of erectile dysfunction (ED) in patients with CAD according to clinical presentation, acute coronary syndrome (ACS) vs. chronic coronary syndrome (CCS), and extent of vessel involvement (single vs. multi-vessel disease). (nih.gov)
- Erectile dysfunction: a marker of silent coronary artery disease. (nih.gov)
- Thus, the present double-blind, randomized study was designed to test the hypothesis that long-term, 6-month supplementation of L-arginine, the precursor of the endothelium-derived vasodilator NO, reverses coronary endothelial dysfunction to acetylcholine in humans with nonobstructive coronary artery disease. (nih.gov)
- Twenty-six patients without significant coronary artery disease on coronary angiography and intravascular ultrasound were blindly randomized to either oral L-arginine or placebo, 3 g TID. (nih.gov)
- This study proposes a role for L-arginine as a therapeutic option for patients with coronary endothelial dysfunction and nonobstructive coronary artery disease. (nih.gov)
- Submit your Twitter account related to Single Coronary Vessel Disease to be featured! (novusbio.com)
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- Single Coronary Vessel Disease is the progression of atherosclerosis in one vessel of the heart. (novusbio.com)
- The symptoms of Single Coronary Vessel Disease include chest tightness, fatigue, and shortness of breath. (novusbio.com)
- Single Coronary Vessel Disease is treated with blood thinning medications, bypass surgery, and angioplasty. (novusbio.com)
- There are some people who are at greater risk for Single Coronary Vessel Disease, but lifestyle changes can improve the outlook for patients. (novusbio.com)
- Explore more on Single Coronary Vessel Disease below! (novusbio.com)
- We have 1206 products for the study of Single Coronary Vessel Disease that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits. (novusbio.com)
- Single Coronary Vessel Disease is also known as Single Vessel Coronary Artery Disease. (novusbio.com)
- Greater coronary artery disease burden confers a significantly higher risk for clinical plaque progression. (ahajournals.org)
- Although the modification of systemic risk factors for further progression of atherosclerosis has reduced the incidence of death and myocardial infarction (MI) by ≈30%, a subset of patients continue to have recurrent symptoms related to coronary artery disease progression and lesion instability. (ahajournals.org)
- The role of the paraoxonase (PON1) codon 192 polymorphism [glutamine (Q)/arginine (R)] in coronary artery disease (CAD) is controversial. (springer.com)
- The aim of the present study was to evaluate whether the PON1 gene polymorphism is an independent risk factor for severity of coronary artery disease in patients from west of Iran. (springer.com)
- Our results indicated that PON1-Arg-192 allele can be important independent risk factor of CAD in a west population of Iran, with carriers of PON1-Arg-192 having an increased frequency of three-vessel disease and also having a distinct plasma lipids profile. (springer.com)
- Kharrazi H, Vaisi-Raygani A, Sabokroh AR, Pourmotabbed T (2006) Association between apolipoprotein E polymorphism and coronary artery disease in the Kermanshah population in Iran. (springer.com)
- Vaisi-Raygani A, Rahimi Z, Nomani H, Tavilani H, Pourmotabbed T (2007) The presence of apolipoprotein ε4 and ε2 alleles augments the risk of coronary artery disease in type 2 diabetic patients. (springer.com)
- Vaisi Raygani A, Rahimi Z, Tavilani H, Pourmotabbed T (2010) Butyrylcholinesterase K variant and the APOE-ε4 allele work in synergy to increase the risk of coronary artery disease especially in diabetic patients. (springer.com)
- Hatmi ZN, Tahvildari S, Gafarzadeh Motlag A, Sabouri Kashani A (2007) Prevalence of coronary artery disease risk factors in Iran: a population based survey. (springer.com)
- This study will use a new imaging technique called optical frequency domain imaging (OFDI) to examine the presence of vulnerable plaques in people with coronary artery disease. (centerwatch.com)
- Many people who have coronary artery disease and are at risk of having a heart attack undergo angioplasty, a procedure that opens a narrowed or blocked blood vessel. (centerwatch.com)
- This study will enroll people with coronary artery disease who are undergoing angioplasty. (centerwatch.com)
- Coronary artery disease (CAD) is the leading cause of mortality worldwide and poses a considerable public health burden. (frontiersin.org)
- Coronary artery disease (CAD) is a maladaptive inflammatory disease of the coronary artery vessel wall that remains one of the leading causes of death worldwide. (frontiersin.org)
- Spontaneous coronary artery dissection (SCAD) is a rare but often fatal cause of ischaemic heart disease occurring predominantly in young or middle aged, otherwise healthy subjects. (bmj.com)
- ABBOTT PARK, Ill., May 24, 2011 /PRNewswire/ -- Abbott (NYSE: ABT) today announced it has received U.S. Food and Drug Administration (FDA) approval for the XIENCE nano™ Everolimus Eluting Coronary Stent System for the treatment of coronary artery disease in small vessels. (fiercepharma.com)
- XIENCE nano, which is based on the same platform as the XIENCE V ® Everolimus Eluting Coronary Stent System, offers physicians in the United States a new option for treating patients with coronary artery disease in vessels as small as 2.25 mm in diameter. (fiercepharma.com)
- I am confident that the highly deliverable XIENCE nano stent, with its thin struts and effective everolimus-eluting platform, will help physicians treat their patients who have coronary artery disease in small vessels. (fiercepharma.com)
- With its cobalt chromium stent design, high deliverability, and everolimus drug coating used to prevent abnormal tissue growth, XIENCE nano is designed to be an optimized treatment for coronary artery disease in patients who have small vessels. (fiercepharma.com)
- XIENCE V is indicated for improving coronary luminal diameter in patients with symptomatic heart disease due to de novo native coronary artery lesions (lesions less than or equal to 28 mm) with reference vessel diameters of 2.25 mm to 4.25 mm. (fiercepharma.com)
- The presence of coronary collaterals may have beneficial effects during myocardial ischemia and may improve cardiovascular outcome in patients with coronary artery disease. (diabetesjournals.org)
- Results were adjusted for age, sex, and severity of coronary artery disease. (diabetesjournals.org)
- CONCLUSIONS -The metabolic syndrome and insulin resistance are not related to the presence of coronary collaterals in patients with documented coronary artery disease. (diabetesjournals.org)
- Well-developed coronary collaterals are associated with improved cardiovascular outcome in terms of limiting myocardial infarction size, prevention of ventricular aneurysm formation ( 16 , 17 ), and future ischemic events ( 18 , 19 ) in patients with coronary artery disease. (diabetesjournals.org)
- Coronary artery bypass grafting is performed for patients with coronary artery disease (CAD) to improve quality of life and to reduce cardiac-related mortality. (centerwatch.com)
- There is a general agreement that already in the early postoperative period CABG surgery improves the disease in patients with symptomatic left main coronary artery stenosis or stenosis of the three main coronary vessels. (centerwatch.com)
- Methods: One hundred and fifty-seven patients with diabetes and previous CABG, who underwent PCI of either a graft vessel (GV) (n=44) or a native vessel (NV) (n=113) in the National Center for Cardiovascular Disease, China, were studied. (medworm.com)
- AbstractPurpose of ReviewTo review the clinical evidence on the use of percutaneous coronary intervention (PCI) revascularization options in left main (LM) disease in comparison with coronary artery bypass graft (CABG). (medworm.com)
- Coronary artery disease (CAD) involving the LM is associated with high morbidity and mortality. (medworm.com)
- In this study, we review the current literature in the management of patients with DM and coronary artery disease undergoing a revascularization procedure.RésuméLes patients atteints de diabète sucré (DS) sont exposés à un risque accru de coronaropathie. (medworm.com)
- We attempted to systematically assess various microvascular cutaneous flow indices in response to reactive hyperaemia in control subjects and in patients with coronary artery disease (CAD), and to correlate these with brachial artery flow-mediated dilation (FMD). (portlandpress.com)
- Statins have long been used to help prevent coronary artery disease, but doctors have recently found that they also have short-term benefit for people with an acute coronary syndrome. (merckmanuals.com)
- Objectives The aim of this study was to investigate the impact of post-percutaneous coronary intervention (PCI) quantitative flow ratio (QFR) on clinical outcomes in patients with de novo 3-vessel disease (3VD) treated with contemporary PCI. (onlinejacc.org)
- What are the effects of dalcetrapib on endothelial function, blood pressure, inflammatory markers, and lipids in patients with, or at risk of, coronary heart disease (CHD)? (acc.org)
- Group 1 consisted of 10 patients who had new onset of refractory rest angina and ischemic ST-T changes, but no infarction, single-vessel coronary disease without collateralization, and normal left ventricular (LV) angiograms. (ovid.com)
- Lipid and protein oxidation and antioxidant status in patients with angiographically proven coronary artery disease. (semanticscholar.org)
- Paraoxonase and arylesterase activities in coronary artery disease. (semanticscholar.org)
- Heart rate: a strong predictor of mortality in subjects with coronary artery disease. (semanticscholar.org)
- Long-term survival in patients with coronary artery disease: importance of peripheral vascular disease. (semanticscholar.org)
- Coronary artery disease in diabetic patients]. (semanticscholar.org)
- Patients with multi-vessel coronary artery disease (CAD) are selected for percutaneous coronary interventions (PCI) or surgical revascularisation. (eurekamag.com)
- Objectives This study investigated the feasibility of visual and quantitative assessment of coronary vessel wall contrast enhancement (CE) for detection of symptomatic atherosclerotic coronary artery disease (CAD) and subclinical coronary vasculitis in autoimmune inflammatory disease (systemic lupus erythematosus [SLE]), as well as the association with aortic stiffness, an established marker of risk. (onlinejacc.org)
- Objectives We investigated the prevalence and clinical risk factors of carotid vessel wall inflammation by means of 18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) in a population consisting of coronary artery disease (CAD) patients. (onlinejacc.org)
- Serum biomarkers of inflammation have emerged as independent predictors of coronary artery disease (CAD). (onlinejacc.org)
- Background Among patients with acute myocardial infarction ( MI ) who have multivessel disease, it is unclear if multivessel percutaneous coronary intervention ( PCI ) improves clinical and quality‐of‐life outcomes compared with culprit‐only intervention. (ahajournals.org)
- Prior observational studies and small randomized studies demonstrated reduced major adverse cardiovascular events, including cardiac death, myocardial infarction, and recurrent angina, as well as repeated revascularization, with multivessel percutaneous coronary intervention among patients seen with ST‐segment elevation myocardial infarction and multivessel disease. (ahajournals.org)
- We have shown that among patients seen with acute myocardial infarction and multivessel disease, performing multivessel percutaneous coronary intervention is associated with lower risk of unplanned readmissions in the short‐term after discharge, but similar angina and quality‐of‐life scores. (ahajournals.org)
- Multivessel coronary artery disease is present among 40% of patients who are seen with ST‐segment elevation myocardial infarction (STEMI) 1 , 2 and up to 70% of those who are seen with non-ST‐segment elevation myocardial infarction (NSTEMI). (ahajournals.org)
- Expected cost-effectiveness of percutaneous coronary intervention versus bypass surgery for the treatment of left main, three vessel, and multi-vessel disease that involves the ostium of the right coronary artery. (utwente.nl)
- Objective: The aim of this study is to present the cost-effectiveness of the percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG) for the following three study populations: patients with left main (LM) and/ or three vessel disease, and multi-vessel treatment involving the right coronary artery (RCA) with aorto-ostial region. (utwente.nl)
- To investigate the accuracy of the 12-lead ECG in localizing the site of coronary artery narrowings, we reviewed abnormal ECGs obtained during myocardial infarction, spontaneous angina or exercise stress testing in 134 patients with angiographically documented one-vessel disease. (elsevier.com)
- These findings should lead to a better understanding of the value and limitations of the 12-lead ECG in localizing coronary artery disease. (elsevier.com)
- Methods: A total of 254 patients with coronary artery disease who underwent three-vessel OCT were divided into tertiles according to FRS. (octnews.org)
- Clinical outcomes of state-of-the-art percutaneous coronary revascularization in patients with de novo three vessel disease: 1-year results of the SYNTAX II study. (ox.ac.uk)
- Aims: To investigate if recent technical and procedural developments in percutaneous coronary intervention (PCI) significantly influence outcomes in appropriately selected patients with three-vessel (3VD) coronary artery disease. (ox.ac.uk)
- In addition, atherosclerosis is a spatially heterogeneous disease and therefore imaging at multiple anatomical levels of the coronary circulation is mandatory. (biomedcentral.com)
- When the need for regeneration arises, for example in the setting of coronary artery disease, a reactivation of embryonic processes ensues, redeploying many of the same molecular regulators. (ox.ac.uk)
- Does Cardiovascular disease relates to disorders of the heart blood vessels and the lung function? (answers.com)
- No, Cardiovascular disease relates to disorders of the heart, and blood vessels but not lungs. (answers.com)
- Comparison of medicine alone, coronary angioplasty, and left internal mammary artery-coronary artery bypass for one-vessel proximal left anterior descending coronary artery disease. (duke.edu)
- Our aim was to describe outcomes with medical therapy, angioplasty, or left internal mammary artery (LIMA) bypass grafting in patients with 1-vessel, proximal LAD disease. (duke.edu)
- Treatment of 1-vessel, proximal LAD disease with medicine, angioplasty, or UMA bypass resulted in comparable adjusted survival. (duke.edu)
- After recording the baseline characteristics, including age, Body Mass Index (BMI), systolic and diastolic blood pressures, smoking, history of hypertension, diabetes mellitus, and family history of Coronary Artery Disease (CAD), blood samples were taken for analysis of endoglin and other biochemical variables. (kowsarpub.com)
- However, there is limited data comparing CMR and FFR in patients with multi-vessel disease. (biomedcentral.com)
- This study aims to evaluate the correlation between myocardial ischemia detected by CMR with FFR in patients with multivessel coronary disease at angiography. (biomedcentral.com)
- There is good concordance between perfusion CMR and FFR for the identification of myocardial ischemia in patients with multi-vessel disease. (biomedcentral.com)
- However, some discrepancy remains and at this stage it is unclear whether CMR underestimates or FFR overestimates the number of ischemic segments in multi-vessel disease. (biomedcentral.com)
- However, there are limited data on their comparability in defining ischemic segments in patients with multi-vessel disease. (biomedcentral.com)
- 9 ] compared SPECT and perfusion CMR in patients with angiographically proven three vessel disease and showed that CMR detected perfusion defects in all three vascular territories in 57 % of patients vs only 11 % with SPECT. (biomedcentral.com)
- It is unknown, whether the use of a high-resolution perfusion technique such as CMR leads to improved concordance for the identification of ischemic segments in multi-vessel disease in comparison with FFR. (biomedcentral.com)
- The aim of this study was to compare the extent of myocardial ischemia based on CMR and FFR in patients with angiographically defined multi-vessel disease. (biomedcentral.com)
- CONCLUSIONS: We conclude that in patients with relevant coronary artery disease, plaque burden and the amount of necrotic core material are greater in the target vessel. (unibas.ch)
- Coronary artery disease (CAD), also known as ischemic heart disease (IHD), is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. (icd.codes)
- The prevalence of these ischemic heart disease levels in fractional flow reserve (FFR) interrogated vessels remains largely unknown. (blogspot.com)
- Integration of FFR, CFR, and IMR supports the existence of differentiated patterns of ischemic heart disease that combine focal and diffuse coronary narrowings with variable degrees of MCD. (blogspot.com)
- The joint European Society of Cardiology and European Association of Cardio-Thoracic Surgery (ESC/EACTS) guidelines on myocardial revascularization collect and summarize the evidence regarding decision-making, diagnostics, and therapeutics in various clinical scenarios of coronary artery disease, including elective, urgent, and emergency settings. (springer.com)
- American guidelines also advocate the institution of the Heart Team, indicating the need for multidisciplinary discussion in patients with left main coronary artery disease (CAD) or complex multivessel CAD. (springer.com)
- Background: Although the protective role of collaterals in coronary artery disease (CAD) is well known, the influence of drugs on collateral function remains controversial. (scienceopen.com)
- Diabetes causes microvascular and macrovascular complications including coronary artery disease (CAD) that ultimately contributes to a high rate of cardiovascular morbidity and mortality. (sciendo.com)
- 3. Haffner SM Lehto S Ronnemaa T Pyorala K Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. (sciendo.com)
- 6. Scognamiglio R Negut C Ramondo A Tiengo A Avogaro A. Detection of Coronary Artery Disease in Asymptomatic Patients With Type 2 Diabetes Mellitus. (sciendo.com)
- Severity of coronary artery disease in type 2 diabetes mellitus: Does the timing matter? (sciendo.com)
- Revascularization for coronary artery disease in diabetes mellitus: Angioplasty stents and coronary artery bypass grafting. (sciendo.com)
- Current Status of Bioresorbable Scaffolds in the Treatment of Coronary Artery Disease. (sciendo.com)
- Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk. (sciendo.com)
- To determine the physiologic impact of two-vessel coronary artery disease and its effect on prognosis, a series of clinical, angiographic, exercise and quantitative thallium-201 (Tl-201) imaging parameters were analyzed in 85 consecutive two-vessel coronary artery disease patients followed for 52 ± 27 months after coronary angiography and Tl-201 scintigraphy. (elsevier.com)
- It was concluded that two-vessel coronary artery disease survival correlates with exercise Tl-201 uptake which reflects exercise induced left ventricular dysfunction. (elsevier.com)
- Studies comparing CV-PCI versus MV-PCI in patients with multivessel coronary artery disease were screened for inclusion in final analysis. (elsevier.com)
- Logistic regression was applied to the clinical, risk factor, and exercise data of consecutive angiographic referrals without prior myocardial infarction to determine an algorithm predicting the probability of triple-vessel/left main coronary artery disease. (elsevier.com)
- The resulting probabilities in the four test groups were then compared with the angiographic findings of triple-vessel/left main coronary artery disease. (elsevier.com)
- The findings suggest that a clinician could expect to avert at least 10 angiograms on patients with less severe disease for every missed case of triple-vessel/left main coronary artery disease by using these probabilities as a basis for the decision to perform angiography. (elsevier.com)
Right corona8
- Multiple adjacent 5-mm cross-sectional images of the proximal right coronary artery were obtained with an in-plane resolution of 0.5×1.0 mm. (ahajournals.org)
- At coronary angiography, left anterior descending coronary artery was occluded with distal perfusion by collateral flow, and proximal coronary aneurysms involving proximal left circumflex (LCX) right coronary artery with diffuse coronary atherosclerosis were present. (biomedsearch.com)
- Ruptures located in the left anterior descending were clustered in the proximal part of the vessel, whereas ruptures located in the right coronary artery were more distally located (P=0.02). (eur.nl)
- We were also able to determine that the patient has a right-dominant heart (meaning that her right coronary artery is the one that perfuses the back part of her heart). (blogspot.com)
- We also got to see the catheters that they use, and I was surprised to learn that there are different catheters for the right coronary artery versus the left. (blogspot.com)
- 0.001), lesions in the right coronary artery (p = 0.001) and diffuse lesions (p = 0.04). (elsevier.com)
- The main portion of the right coronary artery provides blood to the right side of the heart, which pumps blood to the lungs. (clevelandclinic.org)
- The rest of the right coronary artery and its main branch, the posterior descending artery, together with the branches of the circumflex artery, run across the surface of the heart's underside, supplying the bottom portion of the left ventricle and back of the septum. (clevelandclinic.org)
Atherosclerosis7
- We hypothesized that such an approach would allow for in vivo imaging of coronary atherosclerosis. (ahajournals.org)
- Conventional coronary angiography frequently underestimates the true burden of atherosclerosis. (ahajournals.org)
- As reported by Glagov et al, 1 the initial response to endothelial injury and development of atherosclerosis is vessel enlargement, with relative preservation of lumen diameter. (ahajournals.org)
- Effects of acute L-arginine administration in coronary atherosclerosis. (nih.gov)
- Extent of atherosclerosis and remodeling of the left main coronary artery determined by intravascular ultrasound. (semanticscholar.org)
- To code a diagnosis of this type, you must use one of the three child codes of I25.81 that describes the diagnosis 'atherosclerosis of oth coronary vessels w/o angina pectoris' in more detail. (icd.codes)
- Illustration depicting atherosclerosis in a coronary artery. (icd.codes)
Stenosis7
- Quantitative angiographic assessment of proximal coronary artery stenosis was performed in 15 patients with consecutive presentations in two categories defined by clinical and angiographic criteria. (ovid.com)
- Treatment of coronary stenosis in small coronary vessels with the SCB MagicTouch TM was well tolerated. (onlinejacc.org)
- 7) The entropy filter and the Hough transformation methods are applied for each segment to detect stenosis on vessels. (nii.ac.jp)
- The relationship between GV, assessed with continuous glucose monitoring system, and the presence of thin-cap fibroatheroma (TCFA) at the non-culprit plaque with mild-to-moderate stenosis in the non-culprit vessel, was assessed. (octnews.org)
- Vulnerable atherosclerotic plaques, which are associated positively with the presence of more unstable atherosclerotic tissue leading to adverse cardiovascular events, often occur at sites of angiographically intermediate coronary-artery stenosis. (biomedcentral.com)
- Presence of collaterals was highly associated with the degree of coronary stenosis. (scienceopen.com)
- CCO decrease across coronary stenosis is associated with myocardial ischemia on APMR. (tue.nl)
Blood vessel9
- Now we saw that the blood vessel contain a lot of muscle cells. (coursera.org)
- The blood-vessel wall is a complicated structure," says Elazer Edelman, director of the Harvard-MIT Biomedical Engineering Center and cofounder of Pervasis. (medgadget.com)
- An OFDI is a new type of catheter that takes more detailed pictures of blood vessel walls and plaques. (centerwatch.com)
- Next, participants will undergo angioplasty and a stent will be placed at the area of the blood vessel that is narrowed or blocked to keep the blood vessel open. (centerwatch.com)
- coronary blood vessel supplies blood to the heart and drains blood from the heart. (answers.com)
- When any blood vessel is punctured or cut,blood flows out.There are three kinds of blood vessels in the human body. (answers.com)
- In contrast, oxygen and nutrients diffuse across the blood vessel layers and enter interstitial fluid , which carries oxygen and nutrients to the target cells, and carbon dioxide and wastes in the opposite direction. (rug.nl)
- During the surgery, a small part of a blood vessel is taken from another area of the body, usually a vein from the leg, and surgically attached across an area of severe narrowing or blockage, thus bypassing the problem area. (bestheartsurgeoninindia.com)
- When it is damaged, the entire blood vessel becomes unstable and ultimately breaks up. (eurekalert.org)
Revascularization7
- In the balloon angioplasty population small vessel size conveyed an increased requirement for revascularization but did not increase the risk of procedural failure or myocardial infarction during follow-up. (biomedsearch.com)
- We conducted the analysis at 12 months with the pre-specified study endpoints of MACE (major adverse cardiac events) which is composed by target lesion/vessel revascularization (TLR/TVR), target vessel myocardial infarction (TV-MI) and cardiac death. (onlinejacc.org)
- MACE was delineated as a composite of Cardiac Death, Target Vessel Myocardial Infarction (TV-MI) and Target Lesion Revascularization (TLR)/Target Vessel Revascularization (TVR). (onlinejacc.org)
- all-cause death, any myocardial infarction (MI), any coronary artery revascularization, and successful treatment (absence of all-cause death, any coronary artery revascularization, and any MI. (utwente.nl)
- Importantly, this latest edition provides a systematic review of all randomized clinical trials performed since 1980, comparing different strategies of myocardial revascularization, including coronary artery bypass graft (CABG), balloon angioplasty, percutaneous coronary intervention (PCI) with bare-metal stents (BMS) and first- and second-generation drug-eluting stents (DES). (springer.com)
- The first percutaneous coronary revascularization procedure was performed only 13 years thereafter, in 1977. (springer.com)
- Unique to this edition, they provide a systematic review of all randomized clinical trials performed since 1980, comparing different strategies of myocardial revascularization, including CABG, balloon angioplasty, percutaneous coronary intervention (PCI) with bare-metal stents (BMS) and first- and second-generation drug-eluting stents (DES). (springer.com)
Intravascular ultrasound5
- Although intravascular ultrasound allows for imaging of coronary plaque, this invasive technique is inappropriate for screening or serial examinations. (ahajournals.org)
- This case illustrates coronary angiography and intravascular ultrasound images in a patient with SCAD involving all three vessels and treated by stenting. (bmj.com)
- Aims: To compare the global characteristics of patients with and without evidence of plaque rupture (PR) in their coronary tree and to evaluate the phenotype of ruptured plaques using intravascular ultrasound (IVUS) radiofrequency data analysis (IVUS-VH). (eur.nl)
- The SYNTAX-II strategy includes: heart team decision-making utilizing the SYNTAX Score II (a clinical tool combining anatomical and clinical factors), coronary physiology guided revascularisation, implantation of thin strut bioresorbable-polymer drug-eluting stents, intravascular ultrasound (IVUS) guided stent implantation, contemporary chronic total occlusion revascularisation techniques and guideline-directed medical therapy. (ox.ac.uk)
- The purpose of this study was to examine the relationship between conventional cardiovascular risk factors, Lp-PLA2 concentration and plaque structure parameters as assessed by intravascular ultrasound in patients with either stable angina or acute coronary syndromes due to intermediate single-vessel coronary artery lesions. (biomedcentral.com)
Graft8
- Here we present for the first time a case reporting on the placement of coronary stent graft in a peripheral vessel for the management of a peripheral side branch perforation. (hindawi.com)
- Thus, at that time two treatment options appeared reasonable, including (1) placement of a coated stent graft over the popliteal artery, covering the perforated side branch, or (2) placement of a coated small diameter coronary stent graft in the perforated side branch. (hindawi.com)
- inductively heating the conductive ring to fuse attachment of the vessel graft to the restricted artery. (google.es)
- Coronary artery bypass graft (CABG) surgery is one of the most common elective surgical procedure. (centerwatch.com)
- Evidence on how to choose target vessels of percutaneous coronary interventions (PCIs) in diabetic patients post-coronary artery bypass graft (post-CABG) is insufficient. (medworm.com)
- additionally, it makes it possible to evaluate the efficiency of the coronary artery bypass graft surgery performed during open heart operation. (iospress.com)
- Coronary artery bypass graft (CABG) surgery is performed to restore blood flow through the vessels that supply blood to the heart. (bestheartsurgeoninindia.com)
- End points were cardiac death (n = 3), myocardial infarction (n = 6) and coronary bypass graft surgery more than three months after testing (n = 16). (elsevier.com)
Cardiac16
- Catheter-based ultrasound devices provide a unique view of the interior of vessels and the heart's anatomy when diagnosing and treating cardiac and vascular diseases. (medgadget.com)
- Noninvasive MR coronary vessel wall and plaque imaging is particularly challenging owing to cardiac and respiratory motion, small coronary vessel wall thickness, and low contrast-to-noise ratios (CNRs) between the coronary vessel wall and the surrounding epicardial fat, coronary blood, and myocardium. (ahajournals.org)
- Because bulk cardiac motion during the respiratory cycle may exceed a multiple of the coronary wall thickness, accurate respiratory motion compensation is critical for coronary vessel wall imaging and has been successfully applied for bright-blood coronary MRA. (ahajournals.org)
- In the stented population, smaller vessel size was associated with a higher stent:vessel ratio, a greater relative gain and a greater subsequent loss index, and a higher risk of adverse cardiac events. (biomedsearch.com)
- Logistic regression indicated that decreasing vessel size (as a continous variable) was associated with an increasing risk of a cardiac event for both the stent and balloon angioplasty populations. (biomedsearch.com)
- In this paper, we present a fully automated approach to coronary vessel segmentation, which involves calcification or soft plaque delineation in addition to accurate lumen delineation, from 3D Cardiac Computed Tomography Angiography data. (spie.org)
- Background Coronary CE by cardiac magnetic resonance (CMR) is a novel noninvasive approach to visualize gadolinium contrast uptake within the coronary artery vessel wall. (onlinejacc.org)
- Coronary contrast enhancement (CE) by cardiac magnetic resonance (CMR) is a novel, noninvasive approach for visualization of gadolinium contrast uptake within the coronary artery vessel wall. (onlinejacc.org)
- This method makes it possible to determine nutrient cardiac blood circulation by calculation of the rate of heat spreading in sma ll coronary vessels in the myocardium at hypothermia and hyperthermia under the conditions of artificial blood circulation. (iospress.com)
- In addition to the reduced operating time, faster recovery and overall improved patient outcomes associated with minimally invasive procedures , using the automated connector device allows me to perform multi-vessel cardiac bypass surgery with reliable and consistent anastomoses on patients who benefit tremendously from a minimally-invasive approach. (bestheartsurgeoninindia.com)
- Despite considerable progress in recent decades in understanding coronary flow, further advances are impeded primarily due to considerable difficulties in experimental measurement of flow features in the heart which are due to the significant movement during the cardiac cycle, the inaccessibility of deep myocardial layer vessels, the dynamic myocardium-vessel interaction (MVI), and the difficulties in controlling the levels of each flow regulation mechanism under in vivo conditions. (frontiersin.org)
- In a lately revealed examine a global crew led by researchers of the Wihuri Analysis Institute and the College of Helsinki present that the VEGF-B progress issue can be utilized to activate the expansion of vessels inside the guts throughout cardiac ischemic harm. (dopewallpapers.com)
- This novel discovering opens the chance that vessels rising from the inside facet of the guts may very well be additional developed for the remedy of myocardial infarction, which ends from inadequate supply of oxygen to cardiac tissue. (dopewallpapers.com)
- The highlight of this study is that by using VEGF-B, we were able to induce the growth of new vessels from the inner surface of the cardiac ventricles during heart development, and again in adult mice, in the ischemic inner parts of the heart," says MD, PhD Markus Räsänen . (dopewallpapers.com)
- Re-activation of the embryonic vessel progress program in grownup endocardium may very well be a brand new therapeutic technique for cardiac neovascularization after myocardial infarction. (dopewallpapers.com)
- For potential future medical use, the operate of those vessels and their blood move must be additional studied to make sure that they actually improve transport of oxygen and vitamins into the cardiac muscle," confirms the Director of Wihuri Analysis Institute, Academy Professor Kari Alitalo. (dopewallpapers.com)
Lesions13
- Background- With the reduction in restenosis rates by drug-eluting stents, there is new controversy concerning the optimal management of incidental, nontarget lesions identified during percutaneous coronary intervention (PCI). (ahajournals.org)
- Thus, focal prophylactic treatment of potentially vulnerable plaques is not performed because percutaneous coronary intervention (PCI) of intermediate lesions has been shown previously to have restenosis rates similar to those of PCI for symptom-causing lesions, thereby obviating the potential benefits of a prophylactic strategy. (ahajournals.org)
- From March 1986 to March 1990, 265 patients (308 lesions) were implanted with the coronary Wallstent in 6 European centers. (eur.nl)
- The all comers, multicentre Nanolute registry enrolled patients with lesions located in coronary vessels with reference vessel diameter (RVD) ≤ 2.75 mm. (onlinejacc.org)
- In patients with multi-vessel CAD and borderline lesions, FFR measurement identifies those, who can be treated conservatively with a good long-term outcome, and prevents unnecessary PCI. (eurekamag.com)
- Few data exist that correlate lesion-related risk factors such as conventional cardiovascular risks or lipoprotein-associated phospholipase A2 (Lp-PLA2) with tissue types within atherosclerotic plaques in patients with single-vessel and intermediate coronary lesions. (biomedcentral.com)
- One hundred and ninety-two patients with single-vessel and intermediate coronary lesions were enrolled in a cross-sectional study and divided into two groups: stable angina pectoris (SAP) and acute coronary syndrome (ACS) groups. (biomedcentral.com)
- Lp-PLA2, diabetes and NC area were significant predictors of acute coronary lesions, and the predictive value of Lp-PLA2 was confirmed by the finding of a high area-under-the-curve in a ROC analysis (0.837, 95% CI:0.778-0.895, P = 0.000), as well as by the reasonable sensitivity and specificity of cut-off values. (biomedcentral.com)
- GHbA1C and Lp-PLA2 were strong independent predictors of plaque burden and FP and NC area at the minimum lumen lesion in patients with single-vessel and intermediate coronary lesions. (biomedcentral.com)
- Furthermore, Lp-PLA2 has a certain predictive value for acute coronary lesions. (biomedcentral.com)
- From October 1, 1986 to December 31, 1989 directional coronary atherectomy was performed during 1,020 procedures (1,140 lesions) at 14 clinical centers. (elsevier.com)
- Thirty-one patients who underwent Multislice 64 CT assessment of coronary lesions and stent implantation at the level of the significant coronary lesion were included in the study. (sciendo.com)
- Group 1 included patients with coronary lesions located on a vessel with a reference diameter above 3 mm (n = 24) and Group 2 included patients with a coronary lesion located on a vessel with a reference diameter below 3 mm (n = 7). (sciendo.com)
Angioplasty9
- During angioplasty, imaging devices are often used to take pictures of the inside of blood vessels. (centerwatch.com)
- We examined the influence of vessel size using an intention-to-treat approach in 259 patients who underwent stent implantation and in 257 patients who underwent balloon angioplasty alone in the BENESTENT trial. (biomedsearch.com)
- RESEARCH DESIGNS AND METHODS -We conducted a cross-sectional study in 227 patients referred for elective percutaneous transluminal coronary angioplasty to the University Medical Centre Utrecht. (diabetesjournals.org)
- Stenting of the mesenteric vessels is covered only when angioplasty of the vessels would not suffice and after the patient has had a thorough medical evaluation and management of symptoms, and for whom surgical intervention is the likely alternative. (findacode.com)
- The coronary stent has been investigated as an adjunct to percutaneous transluminal coronary angioplasty to obviate the problems of early occlusion and late restenosis. (eur.nl)
- Yoshida R, Takagi K, Morishima I, Morita Y, Kanzaki Y, Tsuboi H. The mechanism and prognosis of vessel perforation following excimer laser coronary angioplasty in the new generation laser catheter era. (termedia.pl)
- Balloon angioplasty was attempted in 32 patients after abrupt vessel closure. (elsevier.com)
- In the absence of severe coronary dissection, abrupt closure after directional atherectomy may be effectively managed with balloon angioplasty in some cases, although coronary bypass operation is often required. (elsevier.com)
- Hypothesis: We aimed to investigate prospectively the prevalence of spontaneously visible and recruitable coronary collaterals in consecutive patients with single‐vessel CAD and the effect of systemic administration of nitroglycerin on these types of collaterals during percutaneous transluminal coronary angioplasty (PTCA). (scienceopen.com)
Stents1
- Success stories range from hydrophilic coatings that increase lubricity of catheters passed through peripheral blood vessels to access the heart, to drug-eluting coatings on stents that keep coronary blood vessels patent (open). (thefreedictionary.com)
Proximal2
- Coronary thrombosis was also present into LCX proximal aneurysm. (biomedsearch.com)
- Proximal coronary segments were visually examined for distribution of CE and quantified for contrast-to-noise ratio (CNR) and total CE area. (onlinejacc.org)
Atherosclerotic2
- Invasive x-ray coronary angiography and bright-blood 2 3 coronary magnetic resonance angiography (MRA) only allow for assessment of luminal vessel diameter and do not provide direct information regarding coronary vessel wall thickness or atherosclerotic plaque. (ahajournals.org)
- The dense binding to vasa vasorum in the saphenous vein suggests a role for 5-HT in closure of these nutrient vessels, which could contribute to the formation of atherosclerotic changes in saphenous vein grafts. (lu.se)
Interventions3
- Interventional angiologists or radiologists may consider such an option for complication management after injury of smaller vessels during peripheral percutaneous interventions. (hindawi.com)
- Interventions in small coronary vessels (reference vessel diameter ≤2.75 mm) constitute a considerable proportion (30-50%) of greater than 1 million coronary catheter-based procedures performed worldwide each year. (onlinejacc.org)
- Increased restenosis in diabetes mellitus after coronary interventions is due to exaggerated intimal hyperplasia. (sciendo.com)
Angiographic3
- Coronary wall thickness and wall area were significantly greater in patients with angiographic CAD. (ahajournals.org)
- Clinical and angiographic outcome of elective stent implantation in small coronary vessels: an analysis of the BENESTENT trial. (biomedsearch.com)
- Quantitative coronary arteriography, using paired perpendicular angiographic views and digital computation, yielded statistically different lesion dimensions and hemodynamic predictions for the two groups. (ovid.com)
Underwent3
- Methods and results: Forty patients underwent three-vessel IVUS-VH interrogation. (eur.nl)
- Methods and Results: The present prospective study involved 46 patients with first-episode acute coronary syndrome (ACS) who underwent optical coherence tomography in the non-culprit vessel. (octnews.org)
- The study patients who underwent coronary angiography were divided into a poor collateral group (Group 1, N = 45) and a good collateral group (Group 2, N = 42), according to Rentrop classification. (kowsarpub.com)
Clinical8
- Role of coronary clinical presentation and extent of coronary vessels involve. (nih.gov)
- Role of coronary clinical presentation and extent of coronary vessels involvement: the COBRA trial. (nih.gov)
- ED prevalence differs across subsets of patients with CAD and is related to coronary clinical presentation and extent of CAD. (nih.gov)
- There was no difference between the two study groups in clinical characteristics or in the coronary blood flow in the response to acetylcholine at baseline. (nih.gov)
- 5,6 However, the incidence of clinical plaque progression in a large, contemporary cohort of patients treated with culprit vessel PCI and medical therapy for secondary prevention is unknown. (ahajournals.org)
- Twelve-month clinical results after treatment of SCB demonstrated low rates of MACE in this small vessel cohort of the NANOLUTE' registry, hence showing an adequate efficacy and safety in this setting. (onlinejacc.org)
- Conclusions We demonstrate that quantification of coronary CE by CNR and total CE area is feasible for detection of subclinical and clinical uptake of gadolinium within the coronary vessel wall. (onlinejacc.org)
- Nicorandil Versus Nitroglycerin for Symptomatic Relief of Angina in Patients With Slow Coronary Flow Phenomenon: A Randomized Clinical Trial. (scienceopen.com)
Circulation5
- By carrying this gene vector into the coronary circulation, it should help the cells that form coronary blood vessels grow. (thefreedictionary.com)
- Coronary circulation: microcirculation. (asahq.org)
- The present study aimed to investigate the relationship between endoglin levels and development of Coronary Collateral Circulation (CCC) in patients with acute coronary syndrome. (kowsarpub.com)
- Collateral circulation is a network of tiny blood vessels, and, under normal conditions, not open. (clevelandclinic.org)
- It is essential for the study of coronary circulation by model simulation, based on a realistic network structure. (frontiersin.org)
Lesion2
- Background: Glycemic variability (GV) is associated with coronary plaque rupture at the culprit lesion in acute myocardial infarction (AMI). (octnews.org)
- The target vessel containing the culprit lesion was identified by angiography. (unibas.ch)
Diameter5
- On the examination report, (a) the original image, (b) the center-line image and (c) the plotted diameter along the center-line for the obtained vessel segments are arranged. (nii.ac.jp)
- Publications] 柳原 圭雄: 'A Study of Magnification and Smoothing effect on Accurate Computerized Measurement of vessel diameter of coronary cineangiograms using a tele-cine converter' MEDICAL IMAGING TECHNOLOGY. (nii.ac.jp)
- Publications] Y.Yanagihara: 'A Study of Magnification and Smoothing Effect on Accurate Computerized measurement of Vessel Diameter of Coronary Cineangiograms using a tele-cine converter. (nii.ac.jp)
- Since a vessel flow depends on its diameter to fourth power, diameters are the logical candidates to guide vascular reconstructions to achieve realistic flows. (frontiersin.org)
- Here, a diameter assignment method was developed where each vessel diameter was determined depending on its downstream tree size, aimed to reduce flow dispersion to within measured range. (frontiersin.org)
Conclusions2
- Conclusions -In vivo free-breathing coronary vessel wall and plaque imaging with MR has been successfully implemented in humans. (ahajournals.org)
- CONCLUSIONS: The distribution of the [3H]-5-HT binding is different in the saphenous vein compared to epicardial coronary and internal mammary artery. (lu.se)
Myocardial ischemia2
- first suggested that isoflurane induces coronary vasodilation and, under appropriate circumstances, causes redistribution of myocardial blood flow contributing to development of regional myocardial ischemia. (asahq.org)
- There was good concordance between the two methods to detect myocardial ischemia on a per-patient (k =0.658 95 % CI 0.383-0.933) level and moderate concordance on a per-vessel (k = 0.453 95 % CI 0.294-0.612) basis. (biomedcentral.com)
Cardiovascular5
- Thus, an understanding of the mechanisms of embryonic coronary vasculogenesis and angiogenesis may prove invaluable in developing novel strategies for cardiovascular regeneration and therapeutic coronary angiogenesis. (ox.ac.uk)
- The cardiovascular system consists of the heart, blood and blood vessels. (answers.com)
- The cardiovascular (from Latin words meaning "heart" and "vessel") system comprises the blood, heart, and blood vessels . (rug.nl)
- The essential components of the human cardiovascular system are the heart , blood and blood vessels . (rug.nl)
- The cardiovascular systems of humans are closed, meaning that the blood never leaves the network of blood vessels . (rug.nl)
Occlusion4
- The early occlusion rate in native vessels and bypass grafts was 19 and 8%, respectively (p = 0.019). (eur.nl)
- Simultaneously with balloon occlusion, we measured coronary artery occlusion pressure via the balloon catheter. (scienceopen.com)
- Coronary occlusion pressure was higher in patients with than in those without collaterals. (scienceopen.com)
- There was no effect of systemic administration of nitroglycerin on appearance or occlusion pressure of coronary collaterals. (scienceopen.com)
Aorta4
- Hi, histonet friends, In one of project, we need to stain the aorta and coronary. (utsouthwestern.edu)
- Blood vessels that lead from the heart that are high in oxygen and nutrients have their first branch off the aorta that goes to these blood vessels. (answers.com)
- The coronary vessels arise by vasculogenesis within the subepicardium and then invade the aorta to make contact with the aortic endothelium. (lifemapsc.com)
- CCO was calculated by dividing coronary CT attenuation by descending aorta CT attenuation. (tue.nl)
Plaque8
- 6 A noninvasive technique that would allow for visualization of plaque area and luminal vessel area narrowing and that also allowed for characterization of the plaque constituents would therefore be of great interest. (ahajournals.org)
- This study will use standard IVUS imaging and OFDI to examine vulnerable plaques within blood vessels of the heart and to evaluate any changes that occur over time in heart blood vessels and plaque. (centerwatch.com)
- Not only can we see if there are areas of narrowing in the coronary blood vessels , but we can also see areas of plaque build-up that may not yet be causing narrowing, but might nonetheless benefit from preventative treatments. (thefreedictionary.com)
- there is already evidence of cholesterol plaque formation in their coronary blood vessels due to their high saturated fat diets and lack of regular exercise. (thefreedictionary.com)
- Adequately virtualizing the coronary lumen plays a crucial role for simulating blood ow by means of fluid dynamics while additionally identifying the outer vessel wall in the case of arteriosclerosis is a prerequisite for further plaque compartment analysis. (spie.org)
- However, an excimer laser, which can vaporize thrombus, suppress platelet aggregation, and ablate the underlying plaque, has recently been shown to be effective in patients with acute coronary syndrome (ACS) [ 5 ]. (termedia.pl)
- Objectives: This study sought to explore the association between the Framingham Risk Score (FRS) and coronary plaque characteristics assessed by optical coherence tomography (OCT) imaging. (octnews.org)
- The present study determined the relationship between GV and coronary plaque vulnerability in the non-culprit vessel. (octnews.org)
Veins1
- The blood vessels that return blood to the heart are called Veins. (answers.com)
Epicardial1
- RESULTS: Microscopic analysis of high resolution autoradiographic images revealed a similar pattern of [3H]-5-HT binding in epicardial coronary and internal mammary artery, where it. (lu.se)
Endothelial function2
- Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans. (nih.gov)
- Long-term oral L-arginine supplementation for 6 months in humans improves coronary small-vessel endothelial function in association with a significant improvement in symptoms and a decrease in plasma endothelin concentrations. (nih.gov)
Arterial2
- Since the coronary micro-vessels are responsible for a major portion of the flow resistance, the auto regulated coronary flow was analyzed in a morphometry-based reconstructed 400 vessel arterial microvascular sub-tree spanning vessel orders 1-6. (frontiersin.org)
- 3) The three major flow control mechanisms which act in concert to actively regulate the coronary arterial diameters, aimed to meet the myocardium metabolic demand ( Feigl, 1983 ). (frontiersin.org)
Small vessels2
- Small vessels often are associated with increased levels of restenosis, or tissue re-growth, following a stent implantation. (fiercepharma.com)
- The results are also encouraging in patients with very small vessels. (onlinejacc.org)
Collaterals5
- The aim of the present study was to determine the influence of the metabolic syndrome and insulin resistance on the presence of coronary collaterals. (diabetesjournals.org)
- Coronary collaterals were graded with Rentrop's classification. (diabetesjournals.org)
- Also, the degree of insulin resistance was not related to the presence of coronary collaterals. (diabetesjournals.org)
- Conclusion: Coronary collaterals were found in more than half of patients with single‐vessel CAD, as the prevalence of recruitable collaterals was slightly higher than that of spontaneously visible collaterals. (scienceopen.com)
- Nitroglycerin did neither recruit nor augment coronary collaterals. (scienceopen.com)
Elective2
- Potential participants were identified after elective diagnostic coronary angiography and informed consent was obtained. (biomedcentral.com)
- METHODS: Sixty patients referred for acute (n = 19) or elective (n = 41) coronary angiography were included. (unibas.ch)