Coronary Vessel Anomalies: Malformations of CORONARY VESSELS, either arteries or veins. Included are anomalous origins of coronary arteries; ARTERIOVENOUS FISTULA; CORONARY ANEURYSM; MYOCARDIAL BRIDGING; and others.Coronary Vessels: The veins and arteries of the HEART.Coronary Angiography: Radiography of the vascular system of the heart muscle after injection of a contrast medium.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Coronary Circulation: The circulation of blood through the CORONARY VESSELS of the HEART.Angioplasty, Balloon, Coronary: Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.Coronary Stenosis: Narrowing or constriction of a coronary artery.Pericardium: A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Blood Vessels: Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.Heart: The hollow, muscular organ that maintains the circulation of the blood.Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Ebstein Anomaly: A congenital heart defect characterized by downward or apical displacement of the TRICUSPID VALVE, usually with the septal and posterior leaflets being attached to the wall of the RIGHT VENTRICLE. It is characterized by a huge RIGHT ATRIUM and a small and less effective right ventricle.Coronary Aneurysm: Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Coronary Thrombosis: Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Endothelium, Vascular: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.Vasodilator Agents: Drugs used to cause dilation of the blood vessels.Vasodilation: The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Vascular Resistance: The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.Vasa Vasorum: Nutrient blood vessels which supply the walls of large arteries or veins.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Coronary Occlusion: Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.Ultrasonography, Interventional: The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Percutaneous Coronary Intervention: A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.Adenosine: A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Calcinosis: Pathologic deposition of calcium salts in tissues.Lymphatic Vessels: Tubular vessels that are involved in the transport of LYMPH and LYMPHOCYTES.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Vasoconstriction: The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.Abnormalities, MultipleArteries: The vessels carrying blood away from the heart.Neovascularization, Physiologic: The development of new BLOOD VESSELS during the restoration of BLOOD CIRCULATION during the healing process.Coronary Care Units: The hospital unit in which patients with acute cardiac disorders receive intensive care.Retinal Vessels: The blood vessels which supply and drain the RETINA.Acetylcholine: A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Congenital Abnormalities: Malformations of organs or body parts during development in utero.Quail: Common name for two distinct groups of BIRDS in the order GALLIFORMES: the New World or American quails of the family Odontophoridae and the Old World quails in the genus COTURNIX, family Phasianidae.Coturnix: A genus of BIRDS in the family Phasianidae, order GALLIFORMES, containing the common European and other Old World QUAIL.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Muscle, Smooth, Vascular: The nonstriated involuntary muscle tissue of blood vessels.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Exercise Test: Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.Contrast Media: Substances used to allow enhanced visualization of tissues.Pelger-Huet Anomaly: Autosomal dominant anomaly characterized by abnormal ovoid shape GRANULOCYTE nuclei and their clumping chromatin. Mutations in the LAMIN B receptor gene that results in reduced protein levels are associated with the disorder. Heterozygote individuals are healthy with normal granulocyte function while homozygote individuals occasionally have skeletal anomalies, developmental delay, and seizures.Veins: The vessels carrying blood away from the capillary beds.Regional Blood Flow: The flow of BLOOD through or around an organ or region of the body.Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Tunica Media: The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.Tunica Intima: The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Sirolimus: A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.Syndrome: A characteristic symptom complex.Myocardial Revascularization: The restoration of blood supply to the myocardium. (From Dorland, 28th ed)Coronary Artery Bypass, Off-Pump: Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).Angina, Unstable: Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.Collateral Circulation: Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Heart Ventricles: The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.Chick Embryo: The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.Urogenital Abnormalities: Congenital structural abnormalities of the UROGENITAL SYSTEM in either the male or the female.Paracrine Communication: Cellular signaling in which a factor secreted by a cell affects other cells in the local environment. This term is often used to denote the action of INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS on surrounding cells.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.Myocardial Contraction: Contractile activity of the MYOCARDIUM.NG-Nitroarginine Methyl Ester: A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Platelet Aggregation Inhibitors: Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Microcirculation: The circulation of the BLOOD through the MICROVASCULAR NETWORK.Vascular Endothelial Growth Factor A: The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Drug-Eluting Stents: Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.Chest Pain: Pressure, burning, or numbness in the chest.Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Morphogenesis: The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.Nitric Oxide Synthase: An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.Tooth Abnormalities: Congenital absence of or defects in structures of the teeth.Multidetector Computed Tomography: Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Recurrence: The return of a sign, symptom, or disease after a remission.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Ultrasonography, Prenatal: The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.Plaque, Atherosclerotic: Lesions formed within the walls of ARTERIES.Regeneration: The physiological renewal, repair, or replacement of tissue.Infant, Newborn: An infant during the first month after birth.Sinus of Valsalva: The dilatation of the aortic wall behind each of the cusps of the aortic valve.Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)Cardiovascular Agents: Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.Myocardial Reperfusion: Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Arterioles: The smallest divisions of the arteries located between the muscular arteries and the capillaries.Fractional Flow Reserve, Myocardial: The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Vascular Malformations: A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.Mammary Arteries: Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Vasomotor System: The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Stem Cells: Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Fetal Diseases: Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Mucocutaneous Lymph Node Syndrome: An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Angina Pectoris, Variant: A clinical syndrome characterized by the development of CHEST PAIN at rest with concomitant transient ST segment elevation in the ELECTROCARDIOGRAM, but with preserved exercise capacity.Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)Aorta: The main trunk of the systemic arteries.Saphenous Vein: The vein which drains the foot and leg.Tomography, Emission-Computed, Single-Photon: A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.Radial Artery: The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.Myocardial Bridging: A malformation that is characterized by a muscle bridge over a segment of the CORONARY ARTERIES. Systolic contractions of the muscle bridge can lead to narrowing of coronary artery; coronary compression; MYOCARDIAL ISCHEMIA; MYOCARDIAL INFARCTION; and SUDDEN CARDIAC DEATH.Anus, Imperforate: A congenital abnormality characterized by the persistence of the anal membrane, resulting in a thin membrane covering the normal ANAL CANAL. Imperforation is not always complete and is treated by surgery in infancy. This defect is often associated with NEURAL TUBE DEFECTS; MENTAL RETARDATION; and DOWN SYNDROME.Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Tomography, Spiral Computed: Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.Myocardial Perfusion Imaging: The creation and display of functional images showing where the blood is flowing into the MYOCARDIUM by following over time the distribution of tracers injected into the blood stream.Ergonovine: An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.Cineangiography: Motion pictures of the passage of contrast medium through blood vessels.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.Dilatation, Pathologic: The condition of an anatomical structure's being dilated beyond normal dimensions.Acute Disease: Disease having a short and relatively severe course.Endothelial Cells: Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.

Anomalous origin of the left coronary artery from the pulmonary artery: natural history and normal pregnancies. (1/601)

Two female patients are described with anomalous origin of the left coronary artery arising from the pulmonary artery who sustained an anterolateral myocardial infarction in infancy. Neither patient received surgical treatment although both have lived to middle age with minimal cardiovascular problems and have had uncomplicated pregnancies. Good exercise tolerance and long term survival may be possible even without surgery for patients with this anomaly.  (+info)

Short left coronary artery trunk as a risk factor in the development of coronary atherosclerosis. Pathological study. (2/601)

The relation between the length of the main left coronary artery and the degree of atherosclerosis in its branches was studied by postmortem examination in 204 subjects aged 20 to 90 years. The findings suggest that in cases with a short main left coronary artery the atherosclerotic lesions in the anterior descending and circumflex branches appear earlier, progress faster at higher levels of severity, and lead more frequently to myocardial infarction, than in cases with a long left coronary artery trunk. In cases over the age of 50 years, where disease is expected to have developed, it was shown that the degree of atherosclerosis in the left anterior descending and circumflex branches was inversely related to the length of the main left coronary artery. The correlation coefficients were -0-527 and -0-428, respectively, and in either case a test for zero correlations was significant (P less than 0-001). The possible changes in the haemodynamic and mechanical conditions associated with the variations of the anatomical pattern of the coronary arteries and their influence in the development of atherosclerosis are discussed. It is suggested that the length of the main left coronary artery is a congenital anatomical and possibly hereditary factor influencing the rate of development of atherosclerosis in the branches of the main left coronary artery.  (+info)

Coronary artery disease with single coronary artery. (3/601)

The authors have reviewed the literature in search of the coexistence of single coronary artery with significant coronary artery disease. Two cases of single right coronary artery are described. In both, the anomalies were unsuspected and diagnosed roentgenographically in life. Both patients had angina pectoris, positive graded-exercise stress tests, and hemodynamically significant obstruction or occlusion to the coronary arteries. In neither case was the stenosis proximal or amenable to bypass surgery.  (+info)

Evolution of risk factors influencing early mortality of the arterial switch operation. (4/601)

OBJECTIVES: The present study was undertaken to determine the independent risk factors for early mortality in the current era after arterial switch operation (ASO). BACKGROUND: Prior reports on factors affecting outcome of the ASO demonstrated that abnormal coronary arterial patterns were associated with increased risk of early mortality. As diagnostic, surgical and perioperative management techniques continue to evolve, the risk factors for the ASO may have changed. METHODS: All patients who underwent the ASO at Children's Hospital, Boston between January 1, 1992 and December 31, 1996 were included. Hospital charts, echocardiographic and cardiac catheterization data and operative reports of all patients were reviewed. Demographics and preoperative, intraoperative and postoperative variables were recorded. RESULTS: Of the 223 patients included in the study (median age at ASO = 6 days and median weight = 3.5 kg), 26 patients had aortic arch obstruction or interruption, 12 had Taussig-Bing anomaly, 12 had multiple ventricular septal defects, 8 had right ventricular hypoplasia and 6 were premature. There were 16 early deaths (7%), with 3 deaths in the 109 patients considered "low risk" (2.7%). Coronary artery pattern was not associated with an increased risk of death. Compared with usual coronary anatomy pattern, however, inverted coronary patterns and single right coronary patterns were associated with increased incidence of delayed sternal closure (p = 0.003) and longer duration of mechanical ventilation (p = 0.008). In a multivariate logistic regression model using only preoperative variables, aortic arch repair at a separate procedure before ASO and smaller birth weight were independent predictors of early mortality. In a second model that included both pre- and intraoperative variables, circulatory arrest time and right ventricular hypoplasia were independent predictors of early death. CONCLUSIONS: The ASO can be performed in the current era without excess early mortality related to uncommon coronary artery patterns. Aortic arch repair before ASO, right ventricular hypoplasia, lower birth weight and longer intraoperative support continue to be independent risk factors for early mortality after the ASO.  (+info)

Unusual congenital coronary anomaly and myocardial ischaemia. (5/601)

Angiography was used to diagnose a rare congenital coronary anomaly with myocardial ischaemia in a woman with typical angina. All three coronary arteries arose from a solitary coronary ostium in the right aortic sinus; the left anterior descending coronary artery followed a septal course, the circumflex coronary artery ran behind the ascending aorta, and the right coronary artery followed a normal course. No significant coronary lumen narrowing was found. Transoesophageal echocardiography confirmed the anomalous origin and course of the aberrant coronary arteries. An exercise test reproduced angina, and ECG changes and myocardial perfusion study showed an anterior reversible defect. In contrast to previous reports, myocardial ischaemia was associated with the septal (intramuscular) course of the left anterior descending coronary artery; there was no other significant coronary artery disease.  (+info)

New signs characteristic of myocardial bridging demonstrated by intracoronary ultrasound and Doppler. (6/601)

BACKGROUND: Large discrepancies exist concerning the incidence of myocardial bridging. This has been reported to be 0.5%-2.5% following coronary angiography but 15%-85% following autopsy. The purpose of the study was to use intravascular ultrasound and intracoronary Doppler to study the morphology and flow characteristics of myocardial bridging in order to find feasible parameters of this syndrome. METHODS AND RESULTS: Intravascular ultrasound was performed in 62/69 patients in whom typical angiographic 'milking effects' were present. In 48 patients, intracoronary Doppler was performed. A specific, echolucent 'half moon' phenomenon surrounding the myocardial bridge was found in all the patients. The thickness of the half moon area was 0.47 +/- 0.19 mm in diastole and 0.52 +/- 0.23 mm in systole. There was systolic compression of the myocardial bridge with a lumen reduction during systole of 36.4 +/- 8.8%. Using intracoronary Doppler, a characteristic early diastolic 'finger tip' phenomenon was observed in 42 (87%) of the patients. All patients showed no or reduced antegrade systolic flow. Coronary flow velocity reserve was 2.03 +/- 0. 54. After intracoronary nitroglycerin injection, retrograde systolic flow occurred in 37 (77%) of the 48 patients, with a velocity of -22. 2 +/- 13.2 cm. s(-1). Intravascular ultrasound revealed atherosclerotic involvement of the proximal segment in 61 (88%) of the 69 patients, with an area stenosis of 42 +/- 13%. No plaques were found in the bridge or distal segments in the 62 patients in whom it was possible to introduce the ultrasound catheter throughout the bridging segment. CONCLUSION: Myocardial bridging is characterized by the following morphological and functional signs: a specific, echolucent half moon phenomenon over the bridge segment, which exists throughout the cardiac cycle; systolic compression of the bridge segment of the coronary artery; accelerated flow velocity at early diastole (finger-tip phenomenon); no or reduced systolic antegrade flow; decreased diastolic/systolic velocity ratio; retrograde flow in the proximal segment, which is provoked and enhanced by nitroglycerin injection.  (+info)

A 72 year old woman with ALCAPA. (7/601)

ALCAPA syndrome (anomalous origin of the left coronary artery from the pulmonary artery), which causes the left coronary artery to grow with an anomalous origin from the pulmonary artery, is a rare disease which may result in myocardial infarction, congestive heart failure, and sometimes death during the early infantile period. A 72 year old woman with ALCAPA syndrome is presented. The asymptomatic patient presented with a cardiac murmur which was discovered during a routine check up for a gynaecological intervention. Coronary cineangiography established the diagnosis. Although surgical correction is the usual treatment for such cases, medical treatment was preferred for this patient because she was asymptomatic without clinical signs of heart failure.  (+info)

Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. (8/601)

Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. To further study the in vivo function of VEGF-B, we have generated Vegfb knockout mice (Vegfb(-/-)). Unlike Vegfa knockout mice, which die during embryogenesis, Vegfb(-/-) mice are healthy and fertile. Despite appearing overtly normal, Vegfb(-/-) hearts are reduced in size and display vascular dysfunction after coronary occlusion and impaired recovery from experimentally induced myocardial ischemia. These findings reveal a role for VEGF-B in the development or function of coronary vasculature and suggest potential clinical use in therapeutic angiogenesis.  (+info)

TY - JOUR. T1 - Reimplantation of anomalous right coronary artery from left main coronary artery. T2 - A surgical option. AU - Karimi, Mohsen. AU - Murdison, Kenneth A. AU - Blackwood, Wesley. AU - Davis, Wesley. PY - 2010/4/1. Y1 - 2010/4/1. N2 - Anomalous right coronary artery (ARCA) from left sinus of Valsalva could present in several forms either being intramural or extramural, and most occurring with separate ostium from left coronary system. ARCA originating from the left main coronary artery (LMCA) is very rare and treatments proposed for this type of anomaly are pulmonary artery translocation or coronary artery bypass grafting (CABG) of the right coronary system. There has not been any report in the literature of successful reimplantation of ARCA from LMCA, to the best of our knowledge, as another surgical option for this anomaly. We are reporting a case of successful surgical reimplantation of an ARCA from LMCA.. AB - Anomalous right coronary artery (ARCA) from left sinus of Valsalva ...
Anomalous left coronary artery from the pulmonary artery (ALCAPA), also known as Bland-White-Garland syndrome (BWG), is a rare congenital coronary artery anomaly and is considered one of the most severe of such anomalies. There are two forms, ba...
DISCUSSION AND CONCLUSION: C-CTA is an effective method in detecting coronary artery diseases, variations and anomalies. There are studies indicating that c-CTA is superior to catheter angiography in the diagnosis of coronary artery anomalies. Coronary artery anomalies are the uncommon category of cardiac diseases. Their incidence in the community is 1-2%. Our study supports that c-CTA is an imaging method that is used in the diagnosis of coronary artery anomalies and variations and provides detailed information ...
Keywords: Anomaly, congenital anomalies, coronary artery nomalies, fistula PCI congenital anomalies, gender, PCI.. Abstract: Background: Although not well established; gender may play a role in the incidence, clinical manifestations, and atherosclerotic burden of Coronary Artery Anomalies (CAAS). Our aim is to investigate the impact of gender on coronary artery anomalies. Methods: All coronary angiograms performed at the University Heart Center Zurich, Switzerland, between January 2000 and December 2016 were investigated. Those of anomalous origin, course and termination (fistula) were included in the analysis with the exclusion of coronary artery aneurysms and myocardial bridges. Results: Out of the original 39577 angiographic studies that included 28550 males and 11026 females, Coronary Artery Anomalies (CAAS) were documented in 130 (0.32%) patients of whom 69.2% (n=90) and 30.8%(n=40) were males and females respectively. However, the overall prevalence of coronary anomalies amongst both ...
An anomalous coronary artery (ACA) is a coronary artery that has an abnormality or malformation. The malformation is congenital (present at birth) and is most often related to the origin or location of the coronary artery. However, there may be other defective areas in the coronary artery. Likewise, it may affect the overall size and shape of the affected coronary artery or arteries. ACA may also occur along with other congenital heart defects.. This condition may also be called congenital coronary artery anomaly (CAA).. Although they are present at birth, ACAs are often not diagnosed until late adolescence or adulthood, because of the lack of symptoms or because symptoms may not be recognized as being caused by ACA. Teens or adults with unknown ACA may have an initial episode of chest pain, heart failure, or even sudden cardiac death before the condition is recognized.. ...
Electron beam tomography (EBT) has been widely used for the assessment of coronary calcification, particularly in patients at risk of coronary artery disease. EB angiography (EBA) has shown significant sensitivity in confirming coronary arterial narrowing involving the proximal and mid-vessel segments. The main advantage of this new imaging technique is its ability to demonstrate the arterial tree, including the coronary arteries, using single breath-hold acquisition while infusing intravenous contrast agent. It does not require a large dose of x-ray radiation exposure followed by a long recumbency for arterial healing, as does conventional coronary angiography. EBA also avoids possible claustrophobic effects of closed tube imaging used by other noninvasive techniques. We present a new application of this technique in patients with anomalous coronary arteries. In 6 patients with congenital anomalous coronary arteries, all coronary artery origins and courses were clearly demonstrated. An example ...
Anomalous left coronary artery from the pulmonary artery: Find the most comprehensive real-world symptom and treatment data on ALCAPA at PatientsLikeMe. 7 patients with ALCAPA experience fatigue, insomnia, depressed mood, pain, and anxious mood.
Learn more about anomalous left coronary artery from the pulmonary artery (ALCAPA) in children and how Boston Childrens Hospital can help.
Learn more about Anomalous Left Coronary Artery from the Pulmonary Artery -- Child at Doctors Hospital of Augusta DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Anomalous Left Coronary Artery from the Pulmonary Artery -- Child at TriStar Southern Hills DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Coronary anomalies are detected in about 1 % of the general population by coronary angiography and have little clinical significance (Angelini et al. 2002). However, a minority of coronary artery anomalies, particularly in which the coronary artery takes an interarterial course, are known to have a risk of myocardial ischemia or sudden cardiac death (Rigatelli et al. 2005). Several possible causes of myocardial ischemia in cases with anomalous coronary artery origin from the wrong aortic sinus with a course between the aorta and the pulmonary artery have been suggested: acute angle take-off of the coronary artery producing a slit-like lumen; closure of the abnormal coronary orifice by a valve-like ridge at aortic expansion; compression of the artery when it courses within the aortic wall (intramural course) or between the aorta and the pulmonary artery; and spasm of the anomalous coronary artery (Basso et al. 2000; Virmani et al. 1984). Virmani et al. (1984), after observing postmortem coronary ...
Coronary artery anomalies (CAAs) include congenital or acquired anomalies that may affect young athletes. Examples of congenital anomalies include anomalous aortic origin of a coronary artery (AAOCA) and anomalous origin of a coronary artery from the pulmonary artery. The main example of acquired CAAs affecting young athletes today is Kawasaki disease, an acquired inflammatory process that targets small vessels, particularly the coronary circulation. For the purpose of this discussion, the focus will be on AAOCA, reportedly the second most common cause of sudden cardiac death (SCD) in young athletes.. The occurrence of SCD generates extreme anxiety in schools, sports organizations, and communities at large, causing it to become a greater societal burden.1 Several factors of AAOCA are unknown, including the exact prevalence, the pathophysiological mechanisms leading to SCD, the actual risk of death for the different types of anatomy, the optimal way to evaluate these patients, and whether or not ...
TY - JOUR. T1 - Anomalous origin of the right coronary artery from the pulmonary artery associated with tetralogy of Fallot. T2 - Description of the pre-surgical diagnosis and surgical repair. AU - Pluchinotta, Francesca R.. AU - Vida, Vladimiro. AU - Milanesi, Ornella. PY - 2011/8. Y1 - 2011/8. N2 - Anomalous origin of the right coronary artery from the pulmonary artery is a rare congenital defect. We describe the case of an infant with anomalous origin of the right coronary artery from the pulmonary artery in association with tetralogy of Fallot. This patient had a pre-operative echocardiographic diagnosis, which was confirmed by angiography, and later underwent a successful surgical repair.. AB - Anomalous origin of the right coronary artery from the pulmonary artery is a rare congenital defect. We describe the case of an infant with anomalous origin of the right coronary artery from the pulmonary artery in association with tetralogy of Fallot. This patient had a pre-operative ...
Catheter-based anatomic and functional assessment of coronary arteries in anomalous aortic origin of a coronary artery, myocardial bridges and Kawasaki disease
Read Siemens clinical case studies to learn more about Computed Tomography in Pediatric Congenital Heart Disease - Anomalous Coronary Arteries
Cardiac and Vas. http://radiology.rsna.org/content/235/3/812.full. Jaydip Datta, MD ; Charles S. White, MD ; Robert C. Gilkeson, MD ; Cristopher A. Meyer, MD ; Sarita Kansal, MD ; Manish L. Jani, MD ; Ronald C. Arildsen, MD ; Katrina Read, DDR. 1 From the Departments of Radiology (J.D., R.C.A.) and Cardiology (S.K.), Vanderbilt University, Nashville, Tenn; Department of Diagnostic Radiology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201 (C.S.W.); Department of Radiology, University Hospital, Cleveland, Ohio (R.C.G.); Department of Radiology, Indiana University School of Medicine, Indianapolis, Ind (C.A.M.); Meharry Medical College, Nashville, Tenn (M.L.J.); and Philips Medical Systems, Cleveland, Ohio (K.R.). Received February 17, 2004; revision requested April 23; revision received July 15; accepted August 18.. PURPOSE: To retrospectively determine the imaging features of anomalous coronary arteries depicted at multi-detector row computed tomographic (CT) ...
An anomalous coronary artery (ACA) is a heart defect. This is something your baby is born with (congenital). In ACA, the blood vessels that supply blood to your childs heart muscle arent normal.
An anomalous coronary artery (ACA) is a heart defect. This is something your baby is born with (congenital). In ACA, the blood vessels that supply blood to your childs heart muscle arent normal.
Anomalous origination of coronary artery from the opposite sinus (ACAOS) is a rare coronary artery anomaly. Right ACAOS with interarterial course is a type of ACAOS, which conveys a high risk for myocardial ischemia or sudden death. We reported a case of right ACAOS with interarterial course in otherwise healthy young male. He was asymptomatic, until an obligatory medical check-up with treadmill test showed a sign of positive ischemic response. Further work-up revealed that he had right ACAOS with interarterial course. Watchful observation was applied to him, while strenuous physical activity and competitive sport were absolutely prohibited.
The term coronary artery anomaly refers to a wide range of congenital abnormalities involving the origin, course, and structure of epicardial coronary arteries. By definition, these abnormalities occur in less than 1% of the general population.
Electron beam computerized tomography (EBCT) during intravenous administration of contrast medium showed an anomalous origin of the left coronary artery from the pulmonary artery, sometimes known as the Bland-White-Garland syndrome. This 28-year-old woman presented with chest pain caused by progressive myocardial ischemia. In this case, a right coronary arteriogram confirmed an enlarged right coronary artery, and both the left anterior descending branch and the circumflex artery were supplied by collateral circulation. The left main artery was connected with the pulmonary trunk during the late phase of the right coronary arteriogram. These axial EBCT images (Figure⇓) were performed with 3-mm thickness and 100-ms acquisition time. Cardiac motionless images allow clear visualization of both the anomalous origin of the left main coronary trunk and enlarged right coronary artery. We can see that the left main trunk supplied the left anterior descending branch and circumflex artery.. ...
We report clinical, CT, invasive coronary angiography and intra-operative findings of a symptomatic elderly man with anomalous origin of left coronary artery from pulmonary artery (ALCAPA). ALCAPA is a rare syndrome with anomalous origin of left main coronary artery (LMCA) from main pulmonary artery (MPA). Survival into adulthood is rare and our case is probably the oldest survivor who has undergone two coronary system repairs for this anomaly. The unique features of our case include: 1) Absence of
Coronary anomalies continue to present an arcane puzzle to most cardiologists. We wish to focus on one particularly fascinating type of defect, in which both coronary arteries arise from the same aortic sinus, or an Anomalous Coronary Artery originates from the Opposite (than normal) Sinus (ACAOS). First reported in 1966 by Jokl and associates1 and more extensively discussed in 1974 by Cheitlin2 and Liberthson3 and their colleagues, anomalous origination of the left coronary artery (LCA) from the right aortic sinus is associated with a high risk of sudden death, usually related to strenuous ex... continue reading about Anomalous Coronary Artery Arising From the Opposite Sinus: Descriptive Features and Pathophysiologic Mechanisms, as Documented ...
Introduction: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare Cardiovascular Disease presented with an incidence of 1:300000 live births. Case Presentation: In this manuscript, four cases of ALCAPA in infancy were described. Two infants were presented with respiratory distress and two with heart a murmur. Their coronary artery was ...
The association between the anatomy of a single coronary artery (SCA) and the surgical risk of aortic valve replacement (AVR) remains unclear due to a lack of studies on this topic. A 73-year-old woman underwent AVR for aortic stenosis. Preoperative coronary angiography results showed a SCA arising from the left coronary sinus. The Manouguian procedure was performed for a small aortic annulus. Intraoperatively, an extracorporeal membrane oxygenator (ECMO) was needed for bypass weaning failure due to newly developed right ventricular dysfunction. Coronary angiography was performed on postoperative day 4, and the findings showed a right coronary artery occlusion just after its origin. After emergent coronary artery bypass surgery, she could be weaned from the ECMO. She was discharged on postoperative day 70 and followed up without complications for 12 months. AVR with the annular enlargement procedure in those with a SCA can result in an unexpected coronary artery occlusion, which should be, therefore,
Formation of the coronary arteries consists of a precisely orchestrated series of morphogenetic and molecular events which can be divided into three distinct processes: vasculogenesis, angiogenesis and arteriogenesis (Risau 1997; Carmeliet 2000). Even subtle perturbations in this process may lead to congenital coronary artery anomalies, as occur in 0.2-1.2% of the general population (von Kodolitsch et al. 2004). Contrary to the previously held dogma, the process of vasculogenesis is not limited to prenatal development. Both vasculogenesis and angiogenesis are now known to actively occur within the adult heart. When the need for regeneration arises, for example in the setting of coronary artery disease, a reactivation of embryonic processes ensues, redeploying many of the same molecular regulators. Thus, an understanding of the mechanisms of embryonic coronary vasculogenesis and angiogenesis may prove invaluable in developing novel strategies for cardiovascular regeneration and therapeutic coronary
Archives of cardiovascular diseases - Vol. 102 - N° 11 - p. 791-792 - Iconography : ST-segment elevation myocardial infarction and fortuitous finding of a single coronary artery - EM|consulte
The occurrence of a single coronary artery (SCA) is rare in the absence of other associated anomalies of the heart and is often… Expand ...
Results: 78 hearts had tricuspid aortic valve and two hearts had bicuspid aortic valve. Anomalous origins of right coronary artery from the left posterior aortic sinus in one heart and the left coronary artery from the non-coronary sinus in another heart were noted. Both right and left coronary arteries arose from the anterior aortic sinus in two hearts with bicuspid aortic valve. Single right coronary ostium was seen in 63 hearts (78.75%), two right coronary ostia were found in 14 hearts (17.5%), three right coronary ostia were found in two hearts (2.5%), and four were found in one heart(1.25%). The left coronary ostium was single in all hearts. The mean diameter of right coronary ostium (RCO) was 3.17±0.87 mm and of the left coronary ostium (LCO) was 4.1±0.83 mm. The relation of the right and left coronary ostia to the sinu-tubular junction, to the bottom of the related sinus and to the commissures was also analyzed in detail ...
Acute Coronary Syndrome in a Patient with a Single Coronary Artery Arising from the Right Sinus of Valsalva: A Case Report Tripodi, Alberto; DellAmore, Andrea; Aquino, Tommaso; Pagliaro, Marco; Fedeli, Corrado; Magnano, Diego; Calvi, Simone; Zussa, Claudio; Lamarra, Mauro; DellAmore, Andrea // Heart, Lung & Circulation;Oct2008, Vol. 17 Issue 5, p421 Coronary anomalies can involve origin or distribution of the artery. Most of these anomalies are not clinically important. A single coronary artery arising from the right coronary sinus of Valsalva is an extremely rare anatomic anomaly. Usually coronary artery malformation is associated with... ...
Westby G. Fisher, MD, FACC is a board certified internist, cardiologist, and cardiac electrophysiologist (doctor specializing in heart rhythm disorders) practicing at NorthShore University HealthSystem in Evanston, IL, USA and is a Clinical Associate Professor of Medicine at University of Chicagos Pritzker School of Medicine. He entered the blog-o-sphere in November, 2005. DISCLAIMER: The opinions expressed in this blog are strictly the those of the author(s) and should not be construed as the opinion(s) or policy(ies) of NorthShore University HealthSystem, nor recommendations for your care or anyone elses. Please seek professional guidance instead ...
Detection of malignant right coronary artery anomaly by multi-slice CT coronary angiography. Dirksen, M. S.; Bax, J. J.; Blom, N. A.; Schalij, M. J.; Jukema, W. J.; Vliegen, H. W.; van der Wall, E. E.; de Roos, A.; Lamb, H. J. // European Radiology;Dec2002 Supplement 3, Vol. 12, pS177 Coronary artery anomalies occur in 0.3-0.8% of the population and infer a high risk for sudden cardiac death in young adults. Diagnosis is usually established during coronary angiography, which is hampered by poor spatial visualization. Magnetic resonance imaging is an alternative, but it is not... ...
Congenital atresia is the maldevelopment or non-development of the ear canal. If your ear canal is not fully developed, it can affect hearing. For treatment, call our specialists at 714-456-7017.
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My grandson, age 10, had aorta surgery when he was 1 wk old and was also born with a VSD, that will require surgery this fall. During his annual cardiology visit this year they discovered a 3rd coronar...
Researchers are still trying to fully understand anomalous aortic origin of a coronary artery (AAOCA) and its relationship to adverse health outcomes in humans, especially children. Using the most up-to-date literature, as well as the input of leading experts in the field, the American Association for Thoracic Surgery (AATS) has released practical guidelines for the identification and treatment of AAOCA, including an overview of the latest data surrounding population-based risk.
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly that is often referred to as Bland-White-Garland syndrome. The effect of gestational age, birth weight, and disease on troponin I and creatine kinase MB in the first year of life. Some of the various questions will be shortly viagra prices described in this article. Similar morphogenetic activities, which are apparently highly conserved, are shared by species that are presumably only distantly related. Tissue tropism of recombinant coxsackieviruses in an adult mouse model. These sites are typically found far from transcription start sites, and most do not contain CpG islands, indicating that they are not in traditional promoter regions.. Whereas a prominent external granular layer remains in generic viagra 100mg chimpanzees, granule cells are scant in other portions of the nucleus. The cost-effectiveness of bevacizumab in the first-line treatment of metastatic colorectal cancer in England ...
Our case can be classified as complex coronary arteriovenous fistulas with termination in the pulmonary trunk with multiple vessels of origin (LCA, RCA and anomalous coronary artery). The dilated costobronchial vessel of origin can be thought of as an extracardiac systemic-to-pulmonary artery collateral vessel or isolated aortopulmonary collateral artery (IAPCA), the coronary supply from RCA & LAD fits the MAPCA definition as well, although intersegmental arteries (typical tortuous posterior hilar vessels) are absent, drainage this proximal in the pulmonary trunk is odd and most isolated MAPCAs would have regressed. [5] Since no cardiac abnormalities were noted indicating an aetiological factor, this persistent left-to-right shunt is probably congenital. The exact aetiology remains challenging, patients history was unremarkable for patent ductus arteriosus or chronic lung disease. [6 ...
Coronary Ostial Stenosis or Atresia (COSA) is a spectrum of rare developmental conditions with different implications in pathophysiologic mechanisms and
Coronary cameral fistula (CCF) is a very rare coronary anomaly in which a communication exists between one of the coronaries and a cardiac chamber. Most of the times it is an incidental finding detected at the time of a coronary angiography. However, sometimes it can have serious presentation like unstable angina, coronary steal or ventricular arrhythmia. We present a rare case of coronary cameral fistula arising from left circumflex artery (LCx) draining in to left ventricular (LV) apex and presenting as unstable angina.
Four hours and 13 minutes into the January race, Dixon suffered a seizure just 25 yards from the finish line. A medical team rushed her off the course, and she was taken to St. Lukes Episcopal Hospital by Life Flight. On Tuesday evening at Memorial Park, in front of her running buddies and TV cameras, Dixon ran those last 25 yards. When Dixon went into cardiac arrest, race officials notified Mulvihill that one of his team members was hospitalized. At St. Lukes, doctors used hypothermia treatment to lower her body temperature and prevent brain damage. Dixon was diagnosed with a congenital coronary anomaly; the left main artery pumping blood to her heart was on the wrong side.
Case Reports in Vascular Medicine is a peer-reviewed, Open Access journal that publishes case reports in all areas of vascular medicine.
16 yr old boy, Postop after CABG for anomalous aortic origin of RCA from left coronary cusp. Complains of chest pain on first postop. day. (Prior EKG - immediately postop. did not show any ST changes ...
It could be speculated that different pathological mechanisms underlie widespread significant brain perfusion decrements in temporal, parietal and frontal regions. Otherwise, a standard radical surgery is still tadalafil price the treatment of choice. To determine the prevalence and characters of tadalafil generic anomalous coronary artery, including the associations of myocardial ischemia. Because of 75 years of apartheid, the new government is faced with a formidable array of problems, both in health care and in the economic domain.. Effect of laparoscopic splenectomy in patients with Hepatitis C and cirrhosis carrying IL28B minor genotype. Preparation, characterization and biological evaluation of cationic 99Tc/99mTc-dioxime complexes. Evaluation of an automatic measuring device for determining certain constituents tadalafil 20mg lowest price of the urinary status The real value lies in use of data for program planning, resource allocation, program design, and evaluation. This is the first ...
This paper presents a brief summary of the recommendations from the Sports Cardiology section of the European Association of Preventive Cardiology (EAPC) on sports-participation in patients with coronary artery disease, coronary artery anomalies or spontaneous dissection of the coronary arteries, all entities being associated with myocardial ischaemia.1 Given the wealth of evidence supporting the benefits of exercise for primary and secondary prevention of coronary artery disease, individuals should be restricted from competitive sport only when a substantial risk of adverse event or disease progression is present. These recommendations aim to encourage regular physical activity including participation in sports and, with reasonable precaution, ensure a high level of safety for all individuals with coronary artery disease. The present document is based on available current evidence, but in most instances because of lack of evidence, also on clinical experience and expert opinion. ...
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Idiopathic dilatation of the pulmonary trunk is a rare congenital anomaly comprising of pulmonary trunk enlargement with or without dilatation of the right and left pulmonary arteries. For this diagnosis, exclusion of pulmonary and cardiac disea...
A Case of Kawasaki Disease with Anomalous Coronary Microvascular Plexus in Left Coronary Artery Lesion Shunting to Coronary Vein in the Early Phase on the Coronary ...
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Anomalous Origin of the Right Coronary Artery from the Left Main Coronary Artery in the Setting of Critical Bicuspid Aortic Valve ...
Anomalous Origin of the Right Coronary Artery from the Left Main Coronary Artery in the Setting of Critical Bicuspid Aortic Valve ...
TY - JOUR. T1 - Anamalous left coronary artery in a calf. AU - Sandusky, G. E.. AU - Smith, C. W.. PY - 1978/1/1. Y1 - 1978/1/1. UR - http://www.scopus.com/inward/record.url?scp=0018009656&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0018009656&partnerID=8YFLogxK. M3 - Article. C2 - 711589. AN - SCOPUS:0018009656. VL - 173. SP - 475. EP - 477. JO - Journal of the American Veterinary Medical Association. JF - Journal of the American Veterinary Medical Association. SN - 0003-1488. IS - 5 I. ER - ...
Anomalous course of the left anterior descending coronary artery between the aorta and pulmonary trunk: a rare cause of myocardial ischaemia at rest. ...
Affiliation:Okayama University,医歯(薬)学総合研究科,教授, Research Field:Food science,Chemical pharmacy,Drug development chemistry, Keywords:タンニン,人工タンニン,ギョリュウ科,抗腫瘍作用,ポリフェノール,高分子ポリフェノール,抗マラリア作用,ワンポット反応,全合成,メチルリチウム(市販品), # of Research Projects:8, # of Research Products:17
Neoplasm:, Organs:, Tissue Culture:, Types of Tumors:, Transplantable Tumors: SAR-91, Genes: Mi*wh - White, Strains: BALB/C. ...
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Ever determined to use the time available to me, Im typing this from Ward 10 (the Outpatients version of Ward 11) while connected to the IV drip, down which is coursing the irradiated blood from somebody elses veins. To bring you bang up to date, things went downhill rapidly after my last post. My haemoglobin…
A person with coronary heart disease has an accumulation of fatty deposits in the coronary arteries. These deposits narrow the arteries and can decrease or block the flow of blood to the heart.
TY - JOUR. T1 - Congenital coronary artery fistula presenting later in life. AU - Abusaid, Ghassan H.. AU - Hughes, Douglas. AU - Khalife, Wissam I.. AU - Parto, Parham. AU - Gilani, Syed A.. AU - Fujise, Ken. PY - 2011/8/1. Y1 - 2011/8/1. N2 - A 53-year-old male presented to our tertiary medical center with complaints of dyspnea and exertional chest pain with mild left ventricular dysfunction and right ventricular enlargement on echocardiography. Cardiac catheterization showed a congenital right coronary artery fistula communicating with the right sided chambers. Using contrast enhanced multi-detector computed tomography scan, the fistula was clearly draining into the coronary sinus. We describe briefly the etiology of coronary artery fistula, its clinical presentation, and the common tests used to confirm diagnosis. We further discuss the types of treatment modalities that are currently available.. AB - A 53-year-old male presented to our tertiary medical center with complaints of dyspnea and ...
In some cases, cardiac anatomy at autopsy after a triathlon may occasionally provide clues to the cause of death.1 Of nine athletes autopsied after a triathlon-related death, only two had cardiac anomalies that could be construed as being a primary cause of death: one with Wolff-Parkinson-White syndrome, the other with a congenital coronary artery anomaly. On the other hand, six had LVH.1. IPO is a plausible cause of triathlon death, particularly since it has been suggested as one possible mechanism in the pathophysiology of drowning.4 In contrast, due to the rarity of IPO-related deaths and lack of known history of IPO in any triathlon death, some have concluded that it is an unlikely cause of death in triathletes.10 ,22 ,23 Nevertheless, several IPO-related deaths have been reported in other settings.42-47 Fatal cases of IPO may be rare but probably under-recognised; unless an episode is witnessed and survival is sufficiently long enough to obtain adequate clinical information to make the ...
BACKGROUND AND PURPOSE Congenital coronary artery fistula (CAF) is an uncommon anomaly. It can become symptomatic, associated with significant morbidity and mortality. We report our experience in percutaneous treatment of CAF. METHODS AND RESULTS Four patients with five CAFs were treated. All were symptomatic at admission. Four fistulas rose from the left anterior descending coronary artery. The fifth originated from the right coronary sinus. All drained into the pulmonary artery. Percutaneous treatment was performed using microcoils in two cases and Hydrocoils in the last two patients (three fistulas). A complete occlusion was achieved in all. There was no complication related with the procedure, and all were asymptomatic at the follow-up. CONCLUSIONS Transcatheter closure of CAFs with microcoils/Hydrocoils is feasible and safe in the anatomically suitable vessels, with low rates of complications. Percutaneous treatment with microcoils/Hydrocoils is a valid option in symptomatic patients.
Aortic Valve Replacement in Bicuspid Aortic Valve with a Single Coronary Artery. . Download books free in pdf. Online library with books, university works and thousands of documents available to read online and download.
An infant with anomalous origin of the left coronary artery from the pulmonary trunk presented with congestive cardiomyopathy. Only cross sectional echocardiography gave a definitive diagnosis. The results of cardiac catheterisation and angiography were inconclusive. Surgical repair was performed successfully after the results of cross sectional echocardiography were known. ...
This is a report on a child who, in the first decade of life, collapsed after effort and died suddenly. There was clinical evidence of acute myocardial ischaemia. At autopsy, a rare cause was found, viz. aberrant origin of the left coronary artery from the right sinus of Valsalva, which then coursed between the aorta and main pulmonary artery. The importance of recognising this congenital coronary artery abnormality is emphasised.
The results of our prospective study suggest that myocardial bridging of the LAD is very frequent in ABS patients, as revealed both by coronary angiography and mostly by CTA compared with controls. Myocardial bridging is usually considered a congenital coronary anomaly with no hemodynamic relevance, but it has been associated with different clinical scenarios, such as typical or atypical angina and myocardial infarction (9-13). From the pathophysiological point of view, myocardial bridging-related myocardial ischemia may be attributed to a combination of different factors: sudden tachycardia (compromising diastolic filling of coronary arteries); increased contractility; coronary spasm and systolic kinking of the coronary arteries (leading to endothelial damage, platelet activation and thrombosis, or mechanical reduction of the blood flow) (9-13).. The true prevalence of myocardial bridging is not fully known because it is usually underdiagnosed by conventional angiography. CTA should be the ...
The surgical reconstructive potential of congenital atresia is generally made after the CT Scan has been fully evaluated. The parents are advised on the potential for reconstruction, based on the degree of development of the childs middle ear, inner ear, and mastoid, as well as the position of the facial nerve and the relative absence of or deformity of the bones of hearing. The most important factor is the development of a good middle ear cavity, not necessarily the size or shapes of the bones of hearing themselves.. The ear surgeon will see and evaluate the child on a yearly basis until age four. At four, if there is a microtia, plans should have already been made by the facial plastic surgeon for reconstruction of the microtia. Coordination between the ear surgeon and the facial plastic surgeon is essential. Scarring could occur when the ear surgeon performs the initial stages. It could compromise the graft material introduced by the facial plastic surgeon.. Most surgical teams advise that ...
Looking for online definition of left coronary artery in the Medical Dictionary? left coronary artery explanation free. What is left coronary artery? Meaning of left coronary artery medical term. What does left coronary artery mean?
Anomalous coronary arteries: Location, degree of atherosclerosis and effect on survival-a report from the Coronary Artery Surgery Study. J Am Coll Cardiol, 1989, 12, 531- 7. 27. , et al. Coronary anatomy in congenitally corrected transposition of the great arteries. Int J Cardiol, 2002, 86, 207-16. 28. B. Congenital heart defects and coronary anatomy. Tex Heart Inst J, 2002, 29, 279-89. 29. , et al. Influence of coronary anatomy on the anatomic repair of transposition of great arteries. Rev Esp Cardiol, 1996, 49, 451-6. Clinical importance of intramural blood vessels in the sino-atrial segment of the conducting system of the heart. Surg Radiol Anat, 1997, 19, 359-63. 17. , et al. A clinical angiographic study of the arterial blood supply to the sinus node. Chest, 1988, 94, 1054-7. 18. Gorlin, R. Coronary anatomy. Major Probl Intern Med, 1976, 11, 40-58. 19. , P. D. Leachman. Variations in coronary artery anatomy: Normal versus abnormal. Cardiovasc Dis, 1980, 7, 357- 70. 20. Angelini, P. Normal ...
Denegri, Andrea; Yousif, Nooraldaem; Manka, Robert; Alkadhi, Hatem; Maier, Willibald (2017). Rare coronary anomaly with hemodynamic consequence: squeezing of the right coronary artery. European Heart Journal, 38(47):3539.. Frangieh, Antonio H; Alibegovic, Jasmina; Templin, Christian; Gaemperli, Oliver; Obeid, Slayman; Manka, Robert; Holy, Erik W; Maier, Willibald; Lüscher, Thomas F; Binder, Ronald K (2017). Intracardiac versus transesophageal echocardiography for left atrial appendage occlusion with watchman. Catheterization and Cardiovascular Interventions, 90(2):331-338.. Jaguszewski, Milosz; Dörig, Manuela; Frangieh, Antonio H; Ghadri, Jelena-Rima; Cammann, Victoria Lucia; Diekmann, Johanna; Napp, L Christian; DAscenzo, Fabrizio; Imori, Yoichi; Obeid, Slayman; Maier, Willibald; Lüscher, Thomas F; Templin, Christian (2016). Safety and efficacy profile of bioresorbable-polylactide-polymer-biolimus-A9-eluting stents versus durable-polymer-everolimus- and zotarolimus-eluting stents in ...
Blood delivered to the coronaries in ASCAPA originates from the pulmonary artery, explaining its reduced oxygen content and lower perfusion pressure.2 Coronary perfusion depends on elevated pulmonary vascular resistance (PVR); as PVR falls in the neonatal period, blood flow increases to the lungs, creating coronary steal and resultant ischemia. Anesthetic goals include maintaining coronary perfusion pressure by maintaining PVR and myocardial contractility.3 A ductus arteriosus maintained with prostaglandin may be the only supply of oxygenated blood to the coronaries.1 The baby depicted in these images had elevated pulmonary pressures of unclear etiology, which allowed survival to 8 weeks of age ...
Coronary MR angiography. Patient with anomalous origin of the right coronary artery from the left aortic sinus of Valsalva. Coronary angiography was performed u
LIVE HARE COURSING IS KEPT ALIVE BY FINANCIAL ASSISTANCE IN THE FORM OF SPONSORSHIP. We anticipate a ban on hare coursing in the near future in Ireland but in the meantime we want to stop as many animals suffering as we can. This means the dying sport of Hare Coursing needs to have all support withdrawn. Proof of the inherent cruelty can be seen in footage like this from the "prestigious" Irish Cup coursing event ...
Looking for online definition of pulmonary trunk in the Medical Dictionary? pulmonary trunk explanation free. What is pulmonary trunk? Meaning of pulmonary trunk medical term. What does pulmonary trunk mean?
Welcome to the ValueMD Albums. Cardiac CT. Images: Normal and Anomalous Coronary Arteries: Dual Source CT in Cardiothoracic Imaging, Coronary Anatomy, CT aorta, Aortic Stenosis, Left ventricular aneurysms are discrete, dyskinetic areas of the left ventricular (LV) wall with a b
The pediatric heart experts at the Nemours Cardiac Center diagnose and treat children with anomalous origin of the pulmonary artery off the aorta at the Nemours/Alfred I. duPont Hospital for Children in Wilmington, Del.
Free, official information about 2011 (and also 2012-2015) ICD-9-CM diagnosis code 753.6, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
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Imaging coroanry artery is generally in the domain of interventional cardiologists. MDCT has helped us to change that. The humble echocardiography can identify the origin* of coronary arteries in most persons. The resolution power of modern day echocardiography is 2mm and the left main ostium is |3.5mm in 99% of population .…
The right coronary artery is one of several major vessels that provide blood to the heart. The right coronary artery splits into the acute marginal arteries and the right posterior coronary artery . Other arteries that are derived from the right and left artery include the left anterior descending artery
Intra-atrial course of the right coronary artery is an uncommon anatomic variation in the course of the right coronary artery, usually involving the mid and distal segments, where the vessel partially or completely courses through the right atria...
Chronic total coronary occlusions (CTO) still remain one of the most technically challenging clinical scenarios in which to perform interventions. Although the antegrad..
This thesis focus on the physiological information, on left ventricular (LV) motion in the long axis, evaluated in routine coronaty angiography sequences and based on previous knowledge from echocardiographic studies. As coronary angiography has become a very frequent examination, a method for assessment of LV function from routine coronary angiograms would probably have a significant impact on clinical work. Therefore, the motion of the left coronary artery is analysed in the studies described below.. In a pilot study of 84 patients, refetTed for coronaty and LV angiography, the systolic descent of the left coronary ostium (LCO) towards apex was measured. This simple manual measure from routine coronary angiograms showed a mean amplitude of 9.6 mm (range 3.0-15.0) and significant linear correlation to ejection fraction (EF) (r = 0.72, SEE = 10.1, p , 0.001).. In the second study, including 28 patients, coronary angiography and echoeardiography was used for measurement of circumflex artery ...
Grigholm, B., P.A. Mayewski, S. Kang, Y. Zhang, U. Morgenstern, M. Schwikowski, S. Kaspari, V. Aizen, E. Aizen, N. Takeuchi, K.A. Maasch, S. Birkel, M. Handley and S. Sneed (2015). 20th Century Dust Lows and the Weakening of the Westerly Winds over the Tibetan Plateau. Geophysical Research Letters, 42(7), 2434-2441. DOI: 10.1002/2015GL063217 [PDF]. ...
By Richard R. Heuser, MD, and Khalid Naqi, MD. Patient History. A 65-year-old army veteran presented with unstable angina. An outside angiogram revealed calcific ostial and proximal right coronary artery (RCA) stenoses.. Methods. The radial approach was utilized with an Ikari 1.5 guiding catheter. The lesion was crossed with a Whisper wire and utilizing the FineCross (Terumo) catheter, this was exchanged for the ViperWire (CSI). Following this, the CSI device debulked the proximal areas of stenosis. An AngioScore balloon performed further enlargement of the lumen. Finally, a 3.5 mm x 33 mm stent was placed (Xience). To optimize the ostial result, we placed the Flash ostial device (Cardinal Health). The final result revealed an appropriate apposition at the origin of the RCA vessel. By deploying a few millimeters more proximal, the Flash ostial device allowed us to get the optimal result at the origin of the vessel.. Discussion. Ostial calcific stenosis always poses a challenge during ...
The circumflex artery, fully titled as the circumflex branch of the left coronary artery, is an artery that branches off from the left coronary artery to supply portions of the heart with oxygenated blood. The circumflex artery itself divides into smaller arterial systems.
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Dr. Matos-Cruz responded: Depends on anatomy. Goal if possible is to achieve, atrioventricular and ventriculoarterial concordance as best possible. Some transpositions of the great arteries are congenitally corrected if baby born with atrioventricular and ventriculoarterial discordance. Is it d or l tga, how many concomitant anomalies are present. If d-tga, no vsd, good valves, no coronary anomalies, good lv and rv, ASD closure and jatene best.
The medial femoral circumflex artery branches off from the deep femoral artery and supplies oxygenated blood to the muscles of the middle of the thigh and hip joint.
Takeuchis diminutive TB228 released at Intermat is the most recent in a long line of compact excavators dating back to 1971. During that time, the Japanese company has made many revisions, and the new model comes with a two-year, 2000-h full machine warranty. Compact excavators must remain small, and the TB228 uses a Tier-4 Yanmar three-cylinder diesel developing 23.5 hp (17.5 kW) and 63 lb·ft (85.3 N·m). A one-touch engine decelerator, electronic monitoring system, and automatic bleed system are installed for safety and convenience. Power is sent through a hydrostatic drive system to either steel or rubber tracks. Three permanently sealed rollers per side help to distribute the 4-psi (28-kPa) ground pressure. Maximum speeds of 1.7 mph (2.8 km/h) in low range and 3 mph (4.9 km/h) in high range are possible. The hydraulic system uses twin variable-displacement piston pumps with two gear pumps to power the vehicle functions. The arm has two-way auxiliary hydraulics, and auxiliary hydraulics ...
Affiliation:東京医科歯科大学,難治疾患研究所,准教授, Research Field:Developmental biology,Molecular biology,Circulatory organs internal medicine, Keywords:エピジェネティクス,ChIP-seq,心臓再生,核内受容体,器官形成,エピゲノム,クロマチン因子,ChIP,翻訳後修飾,可塑性, # of Research Projects:4, # of Research Products:116
Biophys. J., 105:, 2199-2209. (doi:10.1016/j.bpj.2013.09.024) ● Okamoto, M., Namba, T., Shinoda, T., Kondo, T., Watanabe, T., Inoue, Y., Takeuchi, K., Enomoto, Y., Ota, K., Oda, K., Wada, Y., Sagou, K., Saito, K., Sakakibara, A., Kawaguchi, A., Nakajima, K., Adachi, T. Fujimori, T., Ueda, M., Hayashi, S., Kaibuchi, K. and Miyata, T. (2013 ...
Biophys. J., 105:, 2199-2209. (doi:10.1016/j.bpj.2013.09.024) ● Okamoto, M., Namba, T., Shinoda, T., Kondo, T., Watanabe, T., Inoue, Y., Takeuchi, K., Enomoto, Y., Ota, K., Oda, K., Wada, Y., Sagou, K., Saito, K., Sakakibara, A., Kawaguchi, A., Nakajima, K., Adachi, T. Fujimori, T., Ueda, M., Hayashi, S., Kaibuchi, K. and Miyata, T. (2013 ...
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In this article you will find the anatomy, branches and mnemonics related to the axillary artery. Learn all about this blood vessel now at Kenhub!
Duodenum inversum is a rare congenital anomaly of unknown etiology whereby the duodenum travels superiorly to the level of the duodenal bulb and then posteriorly prior to crossing the midline above the pancreas. We describe the first pediatric case of duodenum inversum presenting as partial proximal intestinal obstruction that was medically managed without surgical intervention.
J:204470 Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T, Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis. Mech Dev. 2013 Nov-Dec;130(11-12):519-31 ...
... coronary vessel anomalies MeSH C16.131.240.400.220 --- crisscross heart MeSH C16.131.240.400.280 --- dextrocardia MeSH C16.131. ... transposition of great vessels MeSH C16.131.240.400.915.300 --- double outlet right ventricle MeSH C16.131.240.400.920 --- ... ebstein's anomaly MeSH C16.131.240.400.450 --- eisenmenger complex MeSH C16.131.240.400.560 --- heart septal defects MeSH ...
... coronary vessel anomalies MeSH C14.240.400.220 --- crisscross heart MeSH C14.240.400.280 --- dextrocardia MeSH C14.240.400.280. ... coronary vessel anomalies MeSH C14.280.400.220 --- crisscross heart MeSH C14.280.400.280 --- dextrocardia MeSH C14.280.400.280. ... coronary stenosis MeSH C14.280.647.250.285.200 --- coronary restenosis MeSH C14.280.647.250.290 --- coronary thrombosis MeSH ... coronary stenosis MeSH C14.907.553.470.250.285.200 --- coronary restenosis MeSH C14.907.553.470.250.290 --- coronary thrombosis ...
Coronary artery anomalies (or malformation of coronary vessels) are congenital abnormalities in the coronary anatomy of the ... Many coronary anomalies don't cause symptoms and are recognized only at the time of autopsy. They can be associated with sudden ... Basso C, Maron BJ, Corrado D, Thiene G (May 2000). "Clinical profile of congenital coronary artery anomalies with origin from ... The Congenital Heart Surgeons' Society has started a long-term ongoing study called anomalous aortic origin of a coronary ...
Operations on vessels of heart (36.0) Removal of coronary artery obstruction and insertion of stent(s) (36.1) Bypass ... Total repair of certain congenital cardiac anomalies (35.9) Other operations on valves and septa of heart (35.94) Creation of ... Insertion of vessel-to-vessel cannula (39.94) Replacement of vessel-to-vessel cannula (39.95) Hemodialysis Artificial kidney ... Other operations on vessels (39.90) Insertion of non-drug-eluting peripheral vessel stent(s) (39.91) Freeing of vessel (39.92) ...
... imaging coronary arteries, and in quantifying blood flow across heart valves and in vessels, including congenital heart ... anomalies. Among Pettigrew's trainees and fellows are John N. Oshinski, Ph.D., associate professor, Department of Radiology and ...
Malformation of coronary vessels (Q24.6) Congenital heart block (Q24.8) Other specified congenital malformations of heart ( ... Anomaly of pleura (Q34.1) Congenital cyst of mediastinum (Q34.8) Other specified congenital malformations of respiratory system ... Other malformations of precerebral vessels (Q28.2) Arteriovenous malformation of cerebral vessels (Q28.3) Other malformations ... Ebstein's anomaly (Q22.6) Hypoplastic right heart syndrome (Q22.8) Other congenital malformations of tricuspid valve (Q22.9) ...
See Coronary circulation for description of dominance.) Cardiac vessels Human heart with coronary arteries Heart coronary ... There have been multiple anomalies described, for example the left circumflex having an aberrant course from the right coronary ... It follows the left part of the coronary sulcus, running first to the left and then to the right, reaching nearly as far as the ... The circumflex artery curves to the left around the heart within the coronary sulcus, giving rise to one or more left marginal ...
... blood and blood vessels. Angina Acute coronary syndrome Anomic aphasia Aortic dissection Aortic regurgitation Aortic stenosis ... of the great arteries Double aortic arch Double inlet left ventricle Double outlet right ventricle Ebstein's anomaly GUCH ... Ischemic heart diseases Angina pectoris Acute coronary syndrome Acute myocardial infarction See also Category:Valvular heart ...
It has as contra-indication coronary anomalies. Since 1981 Lecompte has put his Lecompte manoeuvre in use. This is used with ... or shows the vessels clearly on a chest x-ray, MRI, or CT scan - this is of particular importance, as the coronary arteries ... The heart and vessels are accessed via median sternotomy, and a cardiopulmonary bypass machine is used; as this machine needs ... This is a less common variant, and with this arrangement, an unusual coronary artery pattern is common. There are also some ...
The oxygen is transferred via the placenta to the fetus and results in dilatation of the fetal lung vessels. As a consequence, ... This can be fixed by either another coarctectomy[citation needed]. Coronary artery disease (CAD) is a major issue for patients ... Preductal coarctation results when an intracardiac anomaly during fetal life decreases blood flow through the left side of the ... Angioplasty is a procedure done to dilate an abnormally narrow section of a blood vessel to allow better blood flow. This is ...
Fusion of aortic valve leaflets occurs most commonly (≈80%) between the right coronary and left coronary leaflets (RL), which ... Blood does not flow centrally through the aorta in BAV, but along the right-anterior and right-posterior vessel wall for RL and ... Bicuspid aortic valves are the most common cardiac valvular anomaly, occurring in 1-2% of the general population. It is twice ... WSS measurements in RL fusion indicate an increase in pressure applied predominantly to the right-anterior side of the vessel ...
Pratt, FH (1898). "The nutrition of the heart through the vessels of Thebesius and the coronary veins" (PDF). American Journal ... Blake, HA; Manion, WC; Mattingly, TW; Baroldi, G (1964). "Coronary artery anomalies". Circulation. 30: 927-40. doi:10.1161/01. ... and into the coronary sinus. The coronary sinus empties into the right atrium. The thebesian venous network is considered an ... "vessels of Wearn". In his 1928 publication, Wearn himself referred to the arterio-cameral connections (vessels of Wearn) as ...
... is a rare but potentially fatal anomaly. The goal of surgical therapy is establishment of a physiologic bi-coronary circulation ... is a rare birth defect in the heart that occurs when a coronary artery arises from the wrong location on the main blood vessel ... "Anomalous origin of right coronary artery from pulmonary artery with aneurysmal coronary arteries". Cor et Vasa. doi:10.1016/j. ... Over 140 patients with AAOCA have been enrolled by June 2011, making it the largest cohort ever assembled of this anomaly. ...
... of choice is myotomy but bypass surgery can be added when there is proximal coronary obstruction or anatomic anomalies that ... Typically, the arteries rest on top of the heart muscle and feed blood down into smaller vessels that populate throughout the ... A myocardial bridge occurs when one of the coronary arteries tunnels through the myocardium rather than resting on top of it. ... Small amounts of myocardial bridging often are undetectable, as the blood usually flows through the coronary while the heart is ...
Coronary circulation is the circulation of blood in the blood vessels of the heart muscle (myocardium). The vessels that ... Ebstein's anomaly is when the right atrium is significantly enlarged and the heart is shaped like a box. This is very rare and ... "How Is Coronary Heart Disease Diagnosed?". 29 September 2014. Retrieved 25 February 2015. "How Can Coronary Heart Disease Be ... As the left and right coronary arteries run on the surface of the heart, they can be called epicardial coronary arteries. These ...
TAPVC can occur with obstruction, which occurs when the anomalous vein enters a vessel at an acute angle and can cause ... It is associated with other vascular anomalies, and some genetic syndromes such as Turner syndrome. It can be diagnosed with CT ... where blood drains into coronary sinus or directly into right atrium; Infradiaphragmatic (20%), where blood drains into portal ... It is less severe than total anomalous pulmonary venous connection which is a life-threatening anomaly requiring emergent ...
1 Combination Vessel: Persistent truncus arteriosus (minimal cyanosis) 2 Vessels involved: Transposition of great vessels 3 ... The most common cause of right-to-left shunt is the Tetralogy of Fallot, a congenital cardiac anomaly characterized by four co- ... Small physiological, or "normal", shunts are seen due to the return of bronchial artery blood and coronary blood through the ... A right-to-left shunt occurs when: there is an opening or passage between the atria, ventricles, and/or great vessels; and, ...
Something that is patent may also refer to a channel such as a blood vessel, section of bowel, collecting system or duct that ... Anatomical variation is unlike congenital anomalies, which are considered a disorder.[citation needed] Joints, especially ... like that encountered in vital arteries such as coronary arteries and cerebral arteries), or another unspecified obstruction ( ... such as blood vessels or leaf veins. Patent, meaning a structure such as an artery or vein that abnormally remains open, such ...
Coronary artery anomaly. *Anomalous aortic origin of a coronary artery. *Ventricular inversion ... Transposition of the great vessels (TGV) is a group of congenital heart defects involving an abnormal spatial arrangement of ... On chest X-ray, transposition of the great vessels typically shows a cardio-mediastinal silhouette appearing as an "egg on a ... Transposed vessels can present a large variety of atriovenous, ventriculoarterial and/or arteriovenous discordance. The effects ...
Main article: Coronary circulation. Coronary circulation is the circulation of blood in the blood vessels of the heart muscle ( ... Ebstein AnomalyEdit. Ebstein's anomaly is characterized by a right atrium that is significantly enlarged and a heart that is ... Coronary artery diseaseEdit. Main article: Coronary artery disease. Coronary artery disease, also known as "ischemic heart ... myocardium). The vessels that deliver oxygen-rich blood to the myocardium are known as coronary arteries. The vessels that ...
Bulbus cordis anomalies and anomalies of cardiac septal closure (745.0) Common truncus (745.1) Transposition of great vessels ( ... Congenital obstructive anomalies of heart not elsewhere classified (746.85) Coronary artery anomaly congenital (746.86) ... Spinal vessel anomaly (747.83) Persistent fetal circulation (747.9) Unspecified congenital anomaly of circulatory system (748) ... Congenital anomalies of eyelids, lacrimal system, and orbit (744) Congenital anomalies of ear, face, and neck (744.0) Anomalies ...
... generator for use as a component in a heart-lung machine and a treatment for coronary artery disease in which blood vessels ... The recipient infant was 19-day-old Jamie Scudero who had the heart conditions of tricuspid atresia and Ebstein's anomaly. At 3 ... Every Second Counts, McRae, 2006, page 179 "Ebstein's anomaly, which results in a severe malformation of the tricuspid valve ...
Ebstein's anomaly is the displacement of the septal leaflet of the tricuspid valve causing a larger atrium and a smaller ... There are also the coronary sinus and the inferior vena cava valves. The heart valves and the chambers are lined with ... As they mature, they rotate slightly as the outward vessels spiral, and move slightly closer to the heart. In general, the ... The most common form of valvular anomaly is a congenital heart defect (CHD), called a bicuspid aortic valve. This results from ...
Percutaneous coronary intervention (PCI) - Procedures to treat stenotic coronary arteries by accessing through a blood vessel. ... Uhl anomaly - A congenital heart defect in which the right ventricular myocardium is too thin or absent. It is a very rare ... Coronary artery disease (CAD)- Coronary artery disease is a general term for any reduction in coronary circulation. One such ... Diseases of blood vessels - diseases of the blood vessels can be multidisciplinary in nature. For example, medical treatment of ...
Delisi, Lynn E (2008). "The effect of cannabis on the brain: can it cause brain anomalies that lead to increased risk for ... dilation of blood vessels, and fluctuations in blood pressure. There are medical reports of occasional heart attacks or ... particularly those with some degree of coronary artery or cerebrovascular disease, poses greater risks due to the resulting ... congestion of the conjunctival blood vessels), a reduction in intra-ocular pressure, muscle relaxation and a sensation of cold ...
They are often due to damage of blood vessels and connective tissue cells. Many late effects are reduced by fractionating ... coronary artery disease, heart arrhythmia and peripheral artery disease. Radiation-induced fibrosis, vascular cell damage and ... High doses of radiation during pregnancy induce anomalies, impaired growth and intellectual disability, and there may be an ... for example when the tumor is wrapped around a vulnerable structure such as the spinal cord or a major organ or blood vessel.[ ...
Coronary Vessel Anomalies. Vascular Diseases. Aneurysm. Cardiovascular Diseases. Heart Defects, Congenital. Cardiovascular ... Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD). This study is currently recruiting participants. See ... Patient information on spontaneous coronary artery dissection Publications: Tweet MS, Gulati R, Aase LA, Hayes SN. Spontaneous ... The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause tears in blood vessels that ...
OBJECTIVE To evaluate the incidence and impact of radial artery anomalies in patients undergoing transradial coronary ... The overall incidence of radial artery anomaly was 13.8% (n = 212). 108 (7.0%) patients had a high-bifurcating radial origin, ... 35 (2.3%) had a full radial loop, 30 (2.0%) had extreme radial artery tortuosity and 39 (2.5%) had miscellaneous anomalies such ... severe radial tortuosity and other anomalies was 4.6%, 37.1%, 23.3% and 12.9%, respectively. 15 (1%) vascular complications ...
Malformations of CORONARY VESSELS, either arteries or veins. Included are anomalous origins of coronary arteries; ARTERIOVENOUS ...
Coronary Vessel Anomalies. Malformations of CORONARY VESSELS, either arteries or veins. Included are anomalous origins of ... A congenital coronary vessel anomaly in which the left main CORONARY ARTERY originates from the PULMONARY ARTERY instead of ... Coronary Aneurysm. Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to ... Jakarta Acute Coronary Syndrome Registry. Jakarta acute coronary syndrome enrolled patients with acute coronary syndrome ...
... clinicaltrials.gov Clinical trial to determine the early effects of RVX000222 on the changes of lipid and coronary plaque in ... Coronary Vessel Anomalies. Malformations of CORONARY VESSELS, either arteries or veins. Included are anomalous origins of ... A congenital coronary vessel anomaly in which the left main CORONARY ARTERY originates from the PULMONARY ARTERY instead of ... Coronary Aneurysm. Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to ...
Coronary Vessel Anomalies / radiography*. Female. Humans. Lung / blood supply*, radiography. Middle Aged. Tomography, X-Ray ... Arterial supply of a sequestration from the coronary circulation is extremely rare. We present a case of a right middle lobe ... 10028375 - Reduction of vascular tone by introduction of troglitazone to the canine coronary artery.. ...
Coronary angiography and then echocardiography and magnetic resonance imaging revealed a dilated left a ... Coronary Vessel Anomalies / diagnosis*. Echocardiography. Electrocardiography. Heart Defects, Congenital / diagnosis*. Humans. ... Next Document: Evaluation of multiple coronary artery aneurysms in Kawasakis disease by whole heart non-contrast e.... ... Coronary angiography and then echocardiography and magnetic resonance imaging revealed a dilated left anterior descending ...
Also, only three cases with Noonan syndrome and congenital coronary ... occlusion of extramural coronary arteries has not been reported. ... and extramural coronary artery narrowing have been found in ... Coronary Stenosis / congenital*, diagnosis. Coronary Vessel Anomalies / complications, diagnosis. Humans. Male. Noonan Syndrome ... Also, only three cases with Noonan syndrome and congenital coronary artery anomalies have been described. We report a patient ...
Blood Vessel Prosthesis*. Cardiomegaly / radiography. Child, Preschool. Coronary Vessel Anomalies / radiography, surgery*. ...
... which showed an anomalous origin of the right coronary artery (RCA) from the left sinus of Valsalva with a 30-40% fibrous ... A 43-year-old man with angina for 15 years underwent coronary angiography, ... Coronary Angiography. Coronary Artery Bypass. Coronary Circulation / physiology. Coronary Vessel Anomalies / diagnosis, surgery ... After coronary bypass and anastomosis of the right internal mammary artery (RIMA) to the middle segment of RCA, the patient was ...
We have prospectively analysed coronary angiograms of 1521 consecutive patients undergoing cardiac catheteri ... of this study was to investigate the angiographic predictors of exercise induced ischemia in patients with isolated coronary ... Coronary Angiography. Coronary Vessel Anomalies / complications*, physiopathology, radiography*. Dilatation, Pathologic / ... diffuse or segmental coronary ectasia (i.e. isolated coronary ectasia) constituted the main study group. Coronary angiograms ...
Coronary Angiography. Coronary Circulation*. Coronary Vessel Anomalies / physiopathology, radiography, therapy*. Ductus ... Thirteen of 21 vessels demonstrated immediate occlusion. All late angiograms have demonstrated complete occlusion of all ... RESULTS: A total of 61 coils were deployed in 17 patients with various vessels not amenable to treatment with conventional ... and coronary artery fistulae (CAF) (n = 2). Operators were able to control coils and withdraw into the catheter for ...
Coronary Artery Disease / epidemiology * Coronary Vessel Anomalies / epidemiology * Death, Sudden, Cardiac / epidemiology* ... Three of the sudden deaths were due to atherosclerotic coronary artery disease (narrowing of two or three vessels) and one to ... anomalous origin of the left main coronary artery from the right sinus of Valsalva. None of the four runners had prior ...
... anomalous left coronary artery originating from the pulmonary artery, Case study) by South African Journal of Radiology; ... Health, general Child health Children Health aspects Coronary heart disease Care and treatment Case studies Diagnosis ... This is known as myocardial steal; hence the nickname of Al Capone of coronary vessels. (2), (4) The steal phenomenon causes ... Anomalous left coronary artery originating from the pulmonary artery (ALCAPA) is a rare coronary artery anomaly that affects 1 ...
2627944 - Detection of restenosis after coronary angioplasty for single-vessel disease: how relia.... 25276044 - Physiotherapy ... Title: Congenital anomalies Volume: 47 ISSN: 0914-3505 ISO Abbreviation: Congenit Anom (Kyoto) Publication Date: 2007 Dec ... anomalies included abnormalities in ventricular morphology in 18/19 (94.7%), ventriculomegaly in 11/19 (63.1%), increased ...
We carried out cardiac computed tomography (CT) to exclude anomalies of the heart and coronary vessels.... ... We carried out cardiac computed tomography (CT) to exclude anomalies of the heart and coronary vessels. This examination showed ...
"Anatomical consideration of the radial artery for transradial coronary procedures: arterial diameter, branching anomaly and ... vessel tortuosity", Int. J. Cardiol. 101, 421-427 (2005).. Article PubMed Google Scholar ...
Coronary artery fistula (CAF) is defined as an anomalous connection between a coronary artery and a major vessel or a cardiac ... 6. Coronary Artery Fistulas. Congenital coronary artery fistula (CAF) is a rare, isolated anomaly of the coronary artery system ... We present a case of CAF with coronary anomaly. 2. Epidemiology. The incidence of coronary anomalies varies between 0.6% and ... Coronary Anomaly and Coronary Artery Fistula as Cause of Angina Pectoris with Literature Review. Jayanth Koneru,1 Anish Samuel, ...
... a diagnosis of CAT must identify a single arterial vessel giving rise to systemic, pulmonary, and coronary arteries. Cardiac ... This case describes an unusual complex cardiac anomaly in a camelid species. The alpaca cria described in this report presented ... The vessel had a mildly thickened quadricuspid valve and appeared to be the only outflow tract for both the right and left ... Examination of the heart revealed marked dilation of the right atrium, a small PFO, a large VSD, and a single large vessel ...
1926) An unsusual anomaly of the coronary vessels in the malformed heart of a child. Heart 13:273-283. ... while the persisting sinusoids are enlargements of the coronary vessels (comparable with haemangioma), the recesses in IVNC ... Coexisting cardiac anomalies that exclude non-compacted myocardium caused by excessively high pressure exposure of the ... 1932) Congenital heart disease with multiple cardiac anomalies: report of a case showing aortic atresia, fibrous scar in ...
Coronary artery anomalies (or malformation of coronary vessels) are congenital abnormalities in the coronary anatomy of the ... Many coronary anomalies dont cause symptoms and are recognized only at the time of autopsy. They can be associated with sudden ... Basso C, Maron BJ, Corrado D, Thiene G (May 2000). "Clinical profile of congenital coronary artery anomalies with origin from ... The Congenital Heart Surgeons Society has started a long-term ongoing study called anomalous aortic origin of a coronary ...
Computed Tomography of the Coronary Arteries (9781841846576) and a great selection of similar New, Used and Collectible Books ... an assessment of coronary stents * coronary artery anomalies in adults * coronary collaterals and bypass grafts * cardiac ... great thoracic vessels * noncardiac findings on CT calcium screening * left ventricular function * artefacts * the future of ... coronary imaging for normal coronary arteries * coronary pathology and coronary imaging * coronary stenosis * coronary plaque ...
Moreover, the right coronary artery- left atrial fistula is also uncommon.... ... Background Congenital coronary artery fistula in association with aneurysm of the involved coronary artery in adults is rare. ... Therefore, CTA is a noninvasive and accurate imaging technique for detection of major coronary artery anomalies. It allows us ... to define details of coronary vessels and relationship of mediastinal structures in order to plan appropriate management [1]. ...
... is a rare coronary artery anomaly. Right ACAOS with interarterial course is a type of ACAOS, which conveys a high risk for ... Anomalous origination of coronary artery from the opposite sinus (ACAOS) ... Interarterial course means that ectopic coronary artery runs through two big vessels arising from ventricle, that is, aorta and ... is an uncommon coronary anomaly. Its incidence is reported to be around 1.07% [1]. It comprises anomaly of right coronary ...
Coronary Vessel Anomalies, Heart Failure, Coronary Artery Bypass, Percutaneous Coronary Intervention ... Clinical Features, Management, and Prognosis of Spontaneous Coronary Artery Dissection. Aug 02, 2012 Share via: ... YOU ARE HERE: Home , Latest in Cardiology , Clinical Features, Management, and Prognosis of Spontaneous Coronary Artery ... What is the clinical history of patients presenting with spontaneous coronary artery dissection (SCAD)? ...
  • Adults with SCAD will be identified both retrospectively and prospectively.Confirmation of the diagnosis by review of coronary angiography will be required before proceeding with the informed consent process and blood or saliva sample procurement. (clinicaltrials.gov)
  • BACKGROUND The transradial approach for percutaneous coronary procedures has the advantage of reduced access site complications but is associated with specific technical challenges in comparison with the transfemoral approach. (semanticscholar.org)
  • Increased Radial Access Is Not Associated With Worse Femoral Outcomes for Percutaneous Coronary Intervention in the United Kingdom. (semanticscholar.org)
  • 108 (7.0%) patients had a high-bifurcating radial origin, 35 (2.3%) had a full radial loop, 30 (2.0%) had extreme radial artery tortuosity and 39 (2.5%) had miscellaneous anomalies such as radial atherosclerosis and accessory branches. (semanticscholar.org)
  • Procedural failure in patients with high radial bifurcation, radial loop, severe radial tortuosity and other anomalies was 4.6%, 37.1%, 23.3% and 12.9%, respectively. (semanticscholar.org)
  • The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart. (clinicaltrials.gov)
  • Study question: Do mutations within certain genes cause or confer susceptibility to spontaneous coronary artery dissection (SCAD)? (clinicaltrials.gov)
  • The study includes individuals diagnosed with spontaneous coronary artery dissection and their biological parents. (clinicaltrials.gov)
  • Men and women diagnosed with spontaneous coronary artery dissection (SCAD) or and their biological parents. (clinicaltrials.gov)
  • What is the clinical history of patients presenting with spontaneous coronary artery dissection (SCAD)? (acc.org)
  • Spontaneous Coronary Artery Dissection and Its Association With Heritable Connective Tissue Disorders. (acc.org)
  • What is the role of medical and molecular genetic screening for connective tissue disorders in patients with spontaneous coronary artery dissection (SCAD)? (acc.org)
  • Previous studies describing genetics evaluation in spontaneous coronary artery dissection (SCAD) have been retrospective in nature or presented as single case reports. (cdc.gov)
  • Genetics of Spontaneous Coronary Artery Dissection Gains New Momentum. (cdc.gov)
  • My son has a single right coronary artery (left artery arises from the right and goes between the great vessels. (medhelp.org)
  • Noncoronary applications of CT, including evaluation of cardiac masses and imaging of the great vessels, are discussed in Chapters 13 to 16. (ahajournals.org)
  • Normal cardiac development is dependent on PCP signaling 12-15 and both the loop-tail ( Lp ) mouse mutant, 12,13 which has a mutation in the Vangl2 gene, and the Dishevelled 2 ( Dvl2 ) knockout mouse 15 have defects in the alignment of the ventricular chambers with the great vessels (double outlet right ventricle). (ahajournals.org)
  • Another term commonly used to refer to both d-TGA and l-TGA is transposition of the great vessels (TGV), although this term might have an even broader meaning than TGA. (wikipedia.org)
  • Some mutations may be inherited (passed on) from a parent without an apparent blood vessel problem while others may develop for the first time in the affected person. (clinicaltrials.gov)
  • Heart valves separate the atria from the ventricles, or the ventricles from a blood vessel. (wikipedia.org)
  • The major component of HDL consists of apolipoprotein A-I (ApoA I). Recent intervention studies with synthetic HDL particles and recombinant ApoA-I have shown that HDL has the capacity to reverse coronary atherosclerosis. (bioportfolio.com)
  • 1 Atherosclerosis is the most common cause of AMI, although other causes include coronary vasospasm, embolism, vasculitis, and spontaneous coronary dissections. (acc.org)
  • 5 AMI caused by coronary artery dissection may be the first manifestation of FMD and the angiographic appearance of these lesions may represent SCAD or mimic typical atherosclerosis. (acc.org)
  • 13 This high risk of adverse outcomes is related to dissection propagation with coronary wire manipulation, and the attendant risk of more extensive myocardial infarction. (acc.org)
  • Several algorithms were established to locate the culprit vessel in ST elevation myocardial infarction (STEMI) with good accuracy [ 1 - 3 ], but in some clinical scenarios including previous myocardial infarction, it can be misleading if thorough electrocardiogram evaluation is not performed. (hindawi.com)
  • The text concludes with a brief discussion of left ventricular function assessment and presents the editors' perspective on the future of coronary CT, including a few 64-slice studies. (ahajournals.org)