AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and Processes
Coronary VasospasmVasospasm, IntracranialAngina Pectoris, VariantErgonovineCoronary VesselsCoronary AngiographyIsosorbide DinitrateElectrocardiographySubarachnoid HemorrhageCoronary Artery DiseaseCoronary CirculationVasodilator AgentsDiltiazemAngioplasty, Balloon, CoronaryVasoconstrictionCoronary StenosisAngina PectorisCalcium Channel BlockersMyocardial InfarctionAcetylcholineCoronary Artery BypassCardiac Catheterizationrho-Associated KinasesNitratesCoronary DiseaseBasilar ArteryCoronary AneurysmCoronary ThrombosisIschemic Attack, TransientCerebral AngiographyCoronary Restenosis
Coronary Vasospasm
Spasm of the large- or medium-sized coronary arteries.
Vasospasm, Intracranial
Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
Angina Pectoris, Variant
A clinical syndrome characterized by the development of CHEST PAIN at rest with concomitant transient ST segment elevation in the ELECTROCARDIOGRAM, but with preserved exercise capacity.
Ergonovine
An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.
Coronary Vessels
The veins and arteries of the HEART.
Coronary Angiography
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Isosorbide Dinitrate
A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Subarachnoid Hemorrhage
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
Coronary Artery Disease
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Coronary Circulation
The circulation of blood through the CORONARY VESSELS of the HEART.
Vasodilator Agents
Drugs used to cause dilation of the blood vessels.
Diltiazem
A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.
Angioplasty, Balloon, Coronary
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Vasoconstriction
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
Coronary Stenosis
Narrowing or constriction of a coronary artery.
Angina Pectoris
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Calcium Channel Blockers
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Acetylcholine
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Coronary Artery Bypass
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Cardiac Catheterization
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
rho-Associated Kinases
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.
Nitrates
Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Basilar Artery
The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.
Coronary Aneurysm
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
Coronary Thrombosis
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
Ischemic Attack, Transient
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
Cerebral Angiography
Radiography of the vascular system of the brain after injection of a contrast medium.
Coronary Restenosis
Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.

Prostaglandin endoperoxide-dependent vasospasm in bovine coronary arteries after nitration of prostacyclin synthase. (1/422)

In the present study we used a bioassay to study the effects of peroxynitrite (ONOO-) on angiotensin II (A-II)-triggered tension in isolated bovine coronary arteries in order to show the consequences of the previously reported PGI2-synthase inhibition by ONOO- in this model. The following results were obtained: 1. 1 micromol L(-1) ONOO- impaired A-II-induced vasorelaxation and caused a second long lasting constriction phase. Indomethacin (10(-5)M) prevented both effects. U51605, a dual blocker of PGI2-synthase and thromboxane (TX)A2-synthase mimicked the effects of ONOO-. 2. The selective TXA2/prostaglandin endoperoxide (PGH2) receptor antagonist SQ29548 antagonized the second vasoconstriction phase after ONOO- -treatment. Since a generation of TXA2 and 8-iso-prostaglandin F2alpha could be excluded a direct action of unmetabolized PGH2 on the TXA2/PGH2 receptor was postulated. 3. ONOO- dose-dependently inhibited the conversion of 14C-PGH2 into 6-keto-PGF1alpha in isolated bovine coronary arteries with an IC50-value of 100 nM. 4. Immunoprecipitation of 3-nitrotyrosine-containing proteins with a monoclonal antibody revealed PGI2-synthase as the only nitrated protein in bovine coronary arteries treated with 1 micromol 1(-1) ONOO-. 5. Using immunohistochemistry a co-localization of PGI2-synthase and nitrotyrosine-containing proteins was clearly visible in both endothelial and vascular smooth muscle cells. We concluded that ONOO- not only eliminated the vasodilatory, growth-inhibiting, antithrombotic and antiadhesive effects of PGI2 but also allowed and promoted an action of the potent vasoconstrictor, prothrombotic agent, growth promoter, and leukocyte adherer, PGH2.  (+info)

Racial heterogeneity in coronary artery vasomotor reactivity: differences between Japanese and Caucasian patients. (2/422)

Japanese investigators have provided a substantial contribution in the understanding of coronary vasomotor reactivity. On occasions, their findings have been at variance with those undertaken on caucasian patients, raising speculation that vasomotor differences between races may exist. In a comparative review of the published literature, we evaluated the vasoreactive differences among Japanese and caucasian patients with variant angina or myocardial infarction. In variant angina, Japanese patients appear to have diffusely hyperreactive coronary arteries compared with caucasian people, manifested by their segmental rather than focal spasm, hyperreactive nonspastic vessels and multivessel spasm. These differences may reflect the increased basal tone among Japanese variant angina patients and may relate to controversial differences in endothelial nitric oxide production or autonomic nervous system activity. Provocative vasomotor studies of Japanese patients with a recent myocardial infarction report a higher incidence of inducible spasm than caucasian studies, an observation recently supported by a controlled study. Furthermore, the hyperreactivity was diffuse, occurring in both non-infarct- and infarct-related vessels. These observations support the existence of racial coronary vasomotor reactivity differences but require confirmation in further prospectively conducted studies.  (+info)

Intraoperative spasm of coronary and peripheral artery--a case occurring after tourniquet deflation during sevoflurane anesthesia. (3/422)

A 68-yr-old man with a 9-yr history of hypertension presented for hemiglossectomy, segmental resection of the mandible, and the radial forearm free flap grafting. Intraoperatively, facial artery spasm was observed during microvascular suturing of the radial artery to the facial artery. Simultaneously, systolic blood pressure decreased from 100 to 80 torr and the ST segment elevated to 15 mm from the base line. The possible mechanisms responsible for vasospasm in coronary as well as in peripheral arteries under sevoflurane anesthesia are discussed.  (+info)

T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. (4/422)

BACKGROUND: Coronary spasm plays an important role in the pathogenesis of ischemic heart diseases in general. However, the precise mechanism(s) responsible for coronary spasm remains to be elucidated, and we examined the molecular genetics of coronary spasm. METHODS AND RESULTS: We searched for the possible mutations in the endothelial nitric oxide synthase (eNOS) gene in patients with coronary spasm. In this study, we demonstrate the existence of 3 linked mutations in the 5'-flanking region of the eNOS gene (T-786-->C, A-922-->G, and T-1468-->A). The incidence of the mutations was significantly greater in patients with coronary spasm than in the control group (P<0.0001). Multiple logistic regression analysis with forward stepwise selection using the environmental risk factors and the eNOS gene variant revealed that the most predictive independent risk factor for coronary spasm was the mutant allele (P<0.0001). As assessed by luciferase reporter gene assays, the T-786-->C mutation resulted in a significant reduction in eNOS gene promoter activity (P<0.05), whereas neither the A-922-->G nor the T-1468-->A mutation had any affect. CONCLUSIONS: Taken together, these findings strongly suggest that the T-786-->C mutation in the eNOS gene reduces the endothelial NO synthesis and predisposes the patients with the mutation to coronary spasm.  (+info)

A case of vasospastic angina presenting Brugada-type ECG abnormalities. (5/422)

An electrophysiological study and a provocative test of coronary artery spasm was attempted in a 68-year-old man who was having syncopal attacks and chest pain. His electrocardiogram had the characteristics of Brugada syndrome and ventricular fibrillation (VF) was induced by programmed electrical stimulation. ST-segment elevation became exaggerated by procainamide, which could not prevent the induction of VF. Coronary angiography revealed no stenotic lesions, and spasm in the left coronary artery was induced by intracoronary administration of acetylcholine with similar chest pain to that experienced before. Under treatment with diltiazem and flecainide, which suppressed the induction of VF, the patient experienced no recurrence of symptoms despite persistent ST-segment elevation. No previous reports have described coronary spasm associated with Brugada-type ECG abnormalities, and patients with syncope should be evaluated carefully.  (+info)

Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase. (6/422)

The role of peroxynitrite in hypoxia-reoxygenation-induced coronary vasospasm was investigated in isolated bovine coronary arteries. Hypoxia-reoxygenation selectively blunted prostacyclin (PGI2)-dependent vasorelaxation and elicited a sustained vasoconstriction that was blocked by a cyclooxygenase inhibitor, indomethacin, and SQ29548, a thromboxane (Tx)A2/prostaglandin H2 receptor antagonist, but not by CGS13080, a TxA2 synthase blocker. The inactivation of PGI2 synthase, as evidenced by suppressed 6-keto-PGF1 alpha release and a decreased conversion of 14C-prostaglandin H2 into 6-keto-PGF1 alpha, was paralleled by an increased nitration in both vascular endothelium and smooth muscle of hypoxia-reoxygenation-exposed vessels. The administration of the nitric oxide (NO) synthase inhibitors as well as polyethylene-glycolated superoxide dismutase abolished the vasospasm by preventing the inactivation and nitration of PGI2 synthase, suggesting that peroxynitrite was implicated. Moreover, concomitant administration to the organ baths of the two precursors of peroxynitrite, superoxide, and NO mimicked the effects of hypoxia-reoxygenation, although none of them were effective when given separately. We conclude that hypoxia-reoxygenation elicits the formation of superoxide, which causes loss of the vasodilatory action of NO and at the same time yields peroxynitrite. Subsequently, peroxynitrite nitrates and inactivates PGI2 synthase, leaving unmetabolized prostaglandin H2, which causes vasospasm, platelet aggregation, and thrombus formation via the TxA2/prostaglandin H2 receptor.  (+info)

Transient severe mitral regurgitation complicating myocardial stunning due to coronary vasospasm. (7/422)

As in papillary muscle dysfunction complicating mitral prolapse, dyskinesis of the left ventricular wall underlying the papillary muscles has been shown to cause mitral regurgitation following myocardial infarction. Myocardial stunning has been experimentally evidenced to cause mitral regurgitation due to a wall motion abnormality, but it has not yet been clinically defined. We report a clinical case of transient severe mitral regurgitation complicating myocardial stunning caused by coronary vasospasm. Transient wall motion abnormality beneath the anterolateral papillary muscle was considered to be responsible for the mitral regurgitation.  (+info)

Prognostic significance of the pattern of multivessel spasm in patients with variant angina. (8/422)

Multivessel spasm in variant angina is believed to be a major prognostic factor. Three patterns of multivessel spasm have been detected: (1) spasm at different sites on different occasions (migratory spasm); (2) spasm sequentially affecting 2 different sites (sequential spasm); and (3) simultaneous spasm at more than 1 site (simultaneous spasm). The present study investigated the prognosis based on this factor for variant angina without fixed coronary stenosis and examined the influence of multivessel spasm on cardiac events. Twenty-six patients were diagnosed as having variant angina without fixed coronary stenosis using 12-lead 24-h ECG recording system and coronary cineangiography. These patients were followed up prospectively for 57.1+/-7.6 months. Of the 26 patients 13 had single-vessel spasm, 6 had migratory multivessel spasm angina, and 7 showed sequential and/or simultaneous multivessel spasm angina. The survival free of serious cardiac events and of all cardiac events was significantly lower for patients with sequential and/or simultaneous multivessel spasm than for those with migratory multivessel spasm (p<0.05, p<0.05), whereas for patients with migratory multivessel spasm the difference comparison with single-vessel spasm did not attain statistical significance (p = ns, p = ns). The results of this study suggest that there seems to be a high-risk subgroup (i.e., sequential and/or simultaneous multivessel spasm) among patients with variant angina.  (+info)

Secondary coronary artery vasospasm promotes cardiomyopathy progressionSecondary coronary artery vasospasm promotes cardiomyopathy progression
Genetic defects in the plasma membrane-associated sarcoglycan complex produce cardiomyopathy characterized by focal degeneration. The infarct-like pattern of cardiac degeneration has led to the hypothesis that coronary artery vasospasm underlies cardiomyopathy in this disorder. We evaluated the coro …
https://pubmed.ncbi.nlm.nih.gov/14982859/?dopt=Abstract
Coronary vasospasm - wikidocCoronary vasospasm - wikidoc
A discrepancy in the prevalence of coronary artery spasm exists across different ethnicities; in particular, the Japanese population has been reported to have a greater prevalence of this condition compared to Caucasians.[6] In fact, according to a study involving 2251 patients, coronary artery spasm has been estimated to account for approximately 41% of Japanese patients with angina pectoris who underwent angiography.[7] In addition, coronary spasm in Japanese is characterized by a diffuse hyperreactivity as manifested by a segmental pattern of spasm as well as by a multivessel involvement compared to focal involvement in other populations.[8] Moreover, following the administration of acetylcholine early after myocardial infarction for provocation of spasm, there has been three fold higher incidence of coronary spasm and a higher incidence of multivessel spasm among Japanese compared to Caucasians.[9] These findings highlight that the vasomotor reactivity of coronary artery is not homogeneous ...
https://www.wikidoc.org/index.php/Coronary_vasospasm
Letter by Sheikh et al Regarding Article, Invasive Evaluation Of Patients With Angina in the Absence of Obstructive Coronary...Letter by Sheikh et al Regarding Article, Invasive Evaluation Of Patients With Angina in the Absence of Obstructive Coronary...
We applaud the authors of Invasive Evaluation of Patients With Angina in the Absence of Obstructive Coronary Artery Disease, 1 who demonstrated an occult coronary abnormality in more than three quarters of these patients. Identifying the underlying abnormality is especially important for potentially life-threatening conditions that are amenable to treatment such as coronary artery spasm. Coronary spasm is associated with myocardial infarction, arrhythmias, and sudden death yet is responsive to calcium channel blockers and nitrates. Surprisingly, as stated in the accompanying editorial,2 no patient had inducible spasm on acetylcholine provocation. This observation warrants closer scrutiny, particularly in relation to the acetylcholine provocation method used.. Intracoronary acetylcholine administration is used to assess the presence of coronary endothelial function and coronary spasm. Its use is ideal, given its very short half-life and established safety record.. Endothelial function studies ...
http://circ.ahajournals.org/content/132/20/e242
Coronary Artery Vasospasm - Prinzmetals Angina - Cardiology - Highland Hospital - University of Rochester Medical CenterCoronary Artery Vasospasm - Prinzmetals Angina - Cardiology - Highland Hospital - University of Rochester Medical Center
Symptoms are often very similar to pain associated with a more typical heart attack (development of a blockage in a heart artery). Symptoms often occur at rest, and at night. This is different than typical chest pain associated with heart artery blockages which is more typically experience during exertion.. ...
https://www.urmc.rochester.edu/highland/departments-centers/cardiology/conditions/coronary-artery-vasospasm.aspx
北京大学医学部机构知识库([email protected]): Vasospastic angina with J waves formation in patients with sudden loss of consciousness
Vasospastic angina is caused by sudden occlusive vasoconstriction of a segment of an epicardial artery, which can present with a wide spectrum of clinical scenario. We report the cases of two patients diagnosed with vasospastic angina, with one of which presenting with sudden cardiac arrest, while the other presenting with a relatively benign syncope. But both of them have J waves formation on ECG during active ischemia. The diagnosis and management of vasospastic angina, as well as the proposed clinical significance of J waves during coronary spasm are discussed. ...
http://ir.bjmu.edu.cn/handle/400002259/53549
A Case of Coronary Artery Spasm Associated with Lisdexamfetamine UseA Case of Coronary Artery Spasm Associated with Lisdexamfetamine Use
Coronary artery spasm is a cause of myocardial infarction with non-obstructive coronary arteries (MINOCA). Coronary spasm may occur spontaneously or in response to prescribed or illicit drugs. Myocardial injury and cardiomyopathies have been reported in association with the use of stimulants in children and adults with attention deficit hyperactivity disorder (ADHD).
https://clinmedjournals.org/articles/ijcc/international-journal-of-clinical-cardiology-ijcc-4-095.php?jid=ijcc
Coronary Vasospasm and Coronary Atherosclerosis | JACC: Journal of the American College of CardiologyCoronary Vasospasm and Coronary Atherosclerosis | JACC: Journal of the American College of Cardiology
In this issue of the Journal, Ong et al. (1) sought to determine the prevalence of coronary spasm in angina patients with angiographically normal coronary arteries. Of 304 patients with stable angina, 144 (47%) had normal coronary arteries or only minimal irregularities (,20% diameter reduction) at coronary angiography. Acetylcholine (ACH) testing was performed in 124 of the 144 patients and provoked coronary spasm in 77 (62%). Thirty-five patients (45%) with constrictor response presented with epicardial spasm (defined as a ≥75% diameter reduction with reproduction of the symptoms of the patient), and 42 patients (55%) presented with microvascular spasm (defined as ischemic electrocardiographic changes with symptom reproduction, but no epicardial spasm). Overall two-thirds of patients undergoing the ACH test presented with abnormal coronary artery vasomotion, a finding that also confirmed the presence of the ischemic syndrome.. The authors are to be congratulated for attempting to determine ...
http://www.onlinejacc.org/content/59/7/663
Coronary Artery Spasm Symptoms - York CardiologyCoronary Artery Spasm Symptoms - York Cardiology
Definitive diagnosis of coronary artery spasm often begins with a coronary angiogram that is performed with the expectation of finding atherosclerotic narrowing of a heart artery. Patients with coronary artery disease may have one or more plaques in their coronary arteries and unless the blockages are severe, there may be no symptoms. Two patients had coronary artery disease, and three had angiographically normal coronary arteries.. Acting fast at the first sign of heart attack symptoms can save your life and limit damage to your heart. Whether you have had a heart attack or not, if you feel depressed, tell your doctor. You can even have a silent heart attack, one with no symptoms. The symptoms of a heart attack can vary from person to person. To prevent a heart attack, you will most likely need to make lifestyle changes. The patient may need to be hospitalized to prevent a heart attack.. Without normal blood flow from the coronary arteries the heart becomes lack of oxygen and vital nutrients ...
http://yorkcardiology.co.uk/coronary-artery-spasm-symptoms/
Vazospastická angina pectoris - patogeneza, diagnostika a léčba | proLékaře.czVazospastická angina pectoris - patogeneza, diagnostika a léčba | proLékaře.cz
1. Armstrong PW. Stable ischemic syndromes. In: Topol E. Textbook of Cardiovascular Medicine. Philadelphia: Lippincott Raven Publishers 1998. 2. Chatterjee T, Juelke PD, Thum P et al. Successful brachytherapy of coronary vasospasm. Heart 2003; 89(9): 25. 3. Cheng TO. Clinical implication of the hyperventilation test in the diagnosis of coronary artery spasm. Am J Cardiol 1997; 80: 1647. 4. Gersh BJ, Braunwald E, Bonow BO. Chronic coronary artery disease. In: Braunwald E. Heart Disease. A textbook of cardiovascular medicine. 6th ed. Philadelphia: WB Saunders 2001. 5. Halawa B, Salomon P. Activity of transmembrane calcium transport and levels of endothelin-1 in patients with variant angina. Pol Arch Med Wewn 2000; 104(2): 447-453. 6. Hirano Y, Ozasa Y, Yamamoto T et al. Hyperventilation and cold pressor stress echocardiography for noninvasive diagnosis of coronary artery spasm. J Am Soc Echocardiogr 2001; 14(6): 626-633. 7. Hirano Y, Ozasa Y, Yamamoto T et al. Diagnosis of vasospastic angina by ...
https://www.prolekare.cz/casopisy/vnitrni-lekarstvi/2005-5/vazospasticka-angina-pectoris-patogeneza-diagnostika-a-lecba-38197
Coronary Artery Spasm: The Interplay Between Endothelial Dysfunction and Vascular Smooth Muscle Cell Hyperreactivity | ECR...Coronary Artery Spasm: The Interplay Between Endothelial Dysfunction and Vascular Smooth Muscle Cell Hyperreactivity | ECR...
Coronary artery spasm (CAS) is an established cause for anginal chest pain, the cardinal symptom of myocardial ischaemia, in patients with angiographically unobstructed coronary arteries. Evidence from large clinical studies has revealed that about 50% of patients undergoing diagnostic coronary angiography for suspected coronary artery disease (CAD) had either normal or near
https://www.ecrjournal.com/articles/coronary-artery-spasm
Angiographic documented coronary arterial spasm in absence of critical coronary artery stenoses in a patient with variant...Angiographic documented coronary arterial spasm in absence of critical coronary artery stenoses in a patient with variant...
Exercise induced ST elevation in patients with previous myocardial infarction may simply indicate left ventricular wall asynergy. ST segment elevation without prior myocardial infarction is a rare condition and is commonly associated with critical coronary artery stenosis.1 Temporary ST segment elevation associated with chest pain is the hallmark of variant (Prinzmetal) angina, and is a consequence of severe coronary spasm. In a way that is not yet fully understood, exercise can induce coronary spasm in patients with variant angina, as demonstrated in small groups of patients subjected to supine bicycle exercise on the cardiac catheterisation table.2DSE is widely performed as a useful diagnostic tool in patients with known or suspected coronary artery disease. Through its inotropic and chronotropic effects, dobutamine increases the myocardial oxygen demand and may induce ischaemia and segmental wall motion abnormality in the presence of significant coronary artery disease. Myocardial ischaemia ...
http://heart.bmj.com/content/83/4/e4
SUMAVEL DosePro - SUMAVEL® DosePro®
There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of SUMAVEL® DosePro®. SUMAVEL® DosePro® may cause coronary artery vasospasm (Prinzmetals angina). These types of reactions have occurred in some patients without known CAD. For triptan-naïve patients with multiple cardiovascular risk factors who have a negative cardiovascular evaluation, consider administrating the first SUMAVEL® DosePro® dose in a medically-supervised setting and performing an electrocardiogram (ECG) immediately following SUMAVEL® DosePro® administration. For such patients, consider periodic cardiovascular evaluation in intermittent long-term users of SUMAVEL® DosePro®. Life-threatening arrhythmias have been reported within a few hours following the administration of 5-HT1 agonists. Discontinue SUMAVEL® DosePro® if these disturbances occur. Sensations of tightness, pain, pressure, and heaviness have been ...
http://www.sumaveldosepro.com/hcp/
Retin online sales! Retin dose ~ 30s BOM | Barbs Favorites
The mean oral absolute online bioavailability of sales the maxalt retinal detachment symptoms Tablet is retin about online 45, and how to get retin a retin mean peak plasma concentrations (Cmax) are reached in sales approximately 1-1.5 hours (Tmax). Diagnosis Your health care provider may check the size of sales your sales prostate gland directly by putting a sales gloved finger in your rectum and feeling the back wall of the prostate. You can retin ask your pharmacist or sales doctor for information about maxalt that is written for health professionals. Have shortness of breath or chest pain. If there is evidence of CAD or coronary artery vasospasm, maxalt should not be retin administered see contraindications. This medication may be available under multiple brand names and/or in several different forms. You can place the order online, by mail, online by fax or toll-free over the telephone. Your health care provider will also order blood tests, and possibly a sales urine sample. Free Make Up ...
https://blog.barbsfavorites.com/tag/30s-bom/
Evidence for superoxide radical-dependent coronary vasospasm after angioplasty in intact dogs. | CirculationEvidence for superoxide radical-dependent coronary vasospasm after angioplasty in intact dogs. | Circulation
METHODS AND RESULTS Injury was induced by inflation of a balloon catheter 50 +/- 6% above baseline arterial diameter; dogs were followed for 2 hours before death. Epicardial coronary diameters at arteriography and extent of thrombus deposition at serial histological sections were analyzed in controls (n = 20) and in dogs pretreated with superoxide dismutase (SOD, a superoxide radical scavenger, n = 10); other dogs were pretreated with the hydrogen peroxide scavenger catalase (n = 8), the iron chelator deferoxamine (n = 6), or the hydroxyl radical scavenger 1,3-dimethyl-2-thiourea (n = 9). Angioplasty-induced injury was similar among groups. After angioplasty, control dogs exhibited localized and persistent vessel constriction, which was maximal at the initial 5 minutes (28.9 +/- 6.3% diameter decrease versus baseline). Corresponding arterial diameters of SOD-treated dogs were 24-69% larger (95% confidence interval, p less than 0.001) than controls at 5 minutes and, on average, 32% larger than ...
http://circ.ahajournals.org/content/83/5/1705
Perioperative coronary artery spasm leading to myocardial ischaemia after vein graft surgery. | HeartPerioperative coronary artery spasm leading to myocardial ischaemia after vein graft surgery. | Heart
If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patients written consent to publication and send them to the editorial office before submitting your response [Patient consent forms] ...
https://heart.bmj.com/content/49/3/280.responses
The placement of a Wiktor stent for the treatment of vasospastic angina: a case report].
Rev Esp Cardiol. 1997 Nov;50(11):808-11. [The placement of a Wiktor stent for the treat ment of vasospastic angina: a case report]. [Article in Spanish] Rodríguez Díez S1, Lázaro R, Ruiz Nodar JM, Enero J, Romero C, Gómez Recio M, Martínez Elbal L.
https://prinzmetal.org/contents/en-us/d122_%5BThe_placement_of_a_Wiktor_stent_for_the_treatment_of_vasospastic_angina__a_case_report%5D..html
Coronary artery spasm that caused a heart attack - Heart Disease - MedHelpCoronary artery spasm that caused a heart attack - Heart Disease - MedHelp
I am a 43 yo female who had a heart attack. My only risk factor is high bp due to kidney surgery as a child that has been controlled by meds. My EKG indicated damage and I had troponin levels of 6 and ...
https://www.medhelp.org/posts/Heart-Disease/Coronary-artery-spasm-that-caused-a-heart-attack/show/1640501
Coronary Artery SpasmCoronary Artery Spasm
2018 Medmovie.com. All rights reserved. Medmovie.com creates and licenses medical illustrations and animations for educational use. Our goal is to increase your understanding of medical terminology and help communication between patients, caregiver and healthcare professionals. The content in the Media Library is for your information and education purposes only. The Media Library is not a substitute for professional medical advice, diagnosis or treatment for specific medical conditions. ...
https://medmovie.com/library_id/3255/topic/ahaw_0171i/
Coronary Artery Spasm during General Anesthesia | Anesthesiology | ASA PublicationsCoronary Artery Spasm during General Anesthesia | Anesthesiology | ASA Publications
We have emailed you at with instructions on how to set up a new password. If you do not receive an email in the next 24 hours, or if you misplace your new password, please contact:. ASA members: ...
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1957416
Coronary microvascular spasm triggers transient ischemic left ventricular diastolic abnormalities in patients with chest pain...
Impaired coronary microvascular dilatory function can lead to exercise induced myocardial ischemia and angina pectoris even in patients without significant (|50%) obstructive coronary atherosclerosis (APWOCA). Diffuse distal vessel epicardial spasm a
http://www.biomedsearch.com/nih/Coronary-microvascular-spasm-triggers-transient/25075937.html
Does getting scared cause coronary spasm? - Answered by top doctors on HealthTapDoes getting scared cause coronary spasm? - Answered by top doctors on HealthTap
Dr. Stern responded: Yes it can in some. If you are prone to coronary artery spasm, then emotional |a href=/topics/stress track_data={
https://www.healthtap.com/user_questions/16766-does-getting-scared-cause-coronary-spasm
Patients With Vasospastic Angina and Microvascular Resistance Have Worse PrognosisPatients With Vasospastic Angina and Microvascular Resistance Have Worse Prognosis
In patients with angina and nonobstructive coronary-artery disease, coexistence of epicardial coronary spasm and increased microvascular resistance (IMR) is associated with worse outcomes, according to Japanese researchers.
https://www.medscape.com/viewarticle/921410
Coronary artery spasm--Clinical features, pathogenesis and treatment--. - Free Online LibraryCoronary artery spasm--Clinical features, pathogenesis and treatment--. - Free Online Library
Free Online Library: Coronary artery spasm--Clinical features, pathogenesis and treatment--.(Disease/Disorder overview) by Japan Academy Proceedings Series B: Physical and Biological Sciences; Agricultural industry Engineering and manufacturing Biological sciences Acetylcholine Aldehydes Angina pectoris Care and treatment Development and progression Genetic aspects Angiotensin II Coronary vasospasm Complications and side effects Endothelium Genetic polymorphisms Heart attack Ischemia Lipid peroxidation Myocardial ischemia Nitric oxide Smoking
https://www.thefreelibrary.com/Coronary+artery+spasm--Clinical+features%2C+pathogenesis+and+treatment---a0576376601
Zolmitri - MedicScientist :: Total Health PortalZolmitri - MedicScientist :: Total Health Portal
Precautions. Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Elderly: Safety and efficacy in patients , 65 yr not established. Cardiac events/vasoconstriction: Serious coronary events, though extremely rare, can occur after administration of 5-HT1 agonists. Administer first dose in health care providers office to patients at possible risk of unrecognized coronary disease. If symptoms consistent with angina occur, conduct ECG evaluation for ischemic changes. May cause coronary vasospasm in patients with history of CAD. Hepatic Function Impairment: Use with caution; use doses , 2.5 mg.. ...
https://medicscientist.com/drug-salt/zolmitri
An intoxicated, agitated, 20-something with chest painAn intoxicated, agitated, 20-something with chest pain
how do you think this case could have played out differently? Think very few providers would get their cardiologists to bite on young, intoxicated male c/o chest pain with that initial ekg. Im sure most would write it off to early repol. maybe with serial ekgs or echo, but even then itd be a tough sell. Even more concerning is that we all see quite a few intoxicated and agitated young males/females in the department daily. Similar presentations. Feel as though we are so prone to write it off as demand ischemia, coronary vasospasm, trop leak etc.. in this population ...
http://hqmeded-ecg.blogspot.ca/2017/05/an-intoxicated-agitated-20-something.html
An intoxicated, agitated, 20-something with chest painAn intoxicated, agitated, 20-something with chest pain
how do you think this case could have played out differently? Think very few providers would get their cardiologists to bite on young, intoxicated male c/o chest pain with that initial ekg. Im sure most would write it off to early repol. maybe with serial ekgs or echo, but even then itd be a tough sell. Even more concerning is that we all see quite a few intoxicated and agitated young males/females in the department daily. Similar presentations. Feel as though we are so prone to write it off as demand ischemia, coronary vasospasm, trop leak etc.. in this population ...
http://hqmeded-ecg.blogspot.co.uk/2017/05/an-intoxicated-agitated-20-something.html
PDE5 Inhibitors and their Applications: Ingenta ConnectPDE5 Inhibitors and their Applications: Ingenta Connect
PDE5 takes part in many physiological and pathological functions, therefore selective PDE5 inhibitors are potentially useful for a variety of pathologies. At the present, PDE5 inhibitors available on the market have been used for the treatment of erectile dysfunction but, at the same time, are in clinical trials investigating other pathologies such as pulmonary arterial hypertension, coronary vasospasm, benign prostatic hyperplasia etc. This review analyzes the PDE5 inhibitors currently in clinical use, the drugs in clinical trials and the most representative chemical classes published in literature in this last decade ...
http://www.ingentaconnect.com/content/ben/cmc/2010/00000017/00000024/art00001
Acute presentation of vasospastic angina induced by oral capecitabine: a case report | Springer for Research & DevelopmentAcute presentation of vasospastic angina induced by oral capecitabine: a case report | Springer for Research & Development
Introduction Oral capecitabine is an oral prodrug of 5-fluorouracil that has been integrated into the management of multiple cancer types because of the convenience of administration and its efficacy...
https://rd.springer.com/article/10.1186/1752-1947-8-18
Procardia - Best Pharmacy OnlineProcardia - Best Pharmacy Online
Procardia belongs to a class of medications called calcium channel blockers. These medications block the transport of calcium into the smooth muscle cells lining the coronary arteries and other arteries of the body. Since calcium is important in muscle contraction, blocking calcium transport relaxes artery muscles and dilates coronary arteries and other arteries of the body. By relaxing coronary arteries, procardia is useful in treating and preventing chest pain (angina) resulting from coronary artery spasm. Relaxing the muscles lining the arteries of the rest of the body lowers the blood pressure, which reduces the burden on the heart as it pumps blood to the body. Reducing heart burden lessens the heart muscles demand for oxygen, and further helps to prevent angina in patients with coronary artery disease ...
http://bestpharmonline.com/products/procardia.htm
buy-procardia-cheap-onlinebuy-procardia-cheap-online
Procardia belongs to a class of medications called calcium channel blockers. These medications block the transport of calcium into the smooth muscle cells lining the coronary arteries and other arteries of the body. Since calcium is important in muscle contraction, blocking calcium transport relaxes artery muscles and dilates coronary arteries and other arteries of the body. By relaxing coronary arteries, procardia is useful in treating and preventing chest pain (angina) resulting from coronary artery spasm. Relaxing the muscles lining the arteries of the rest of the body lowers the blood pressure, which reduces the burden on the heart as it pumps blood to the body. Reducing heart burden lessens the heart muscles demand for oxygen, and further helps to prevent angina in patients with coronary artery disease ...
http://alledstar.com/products/procardia
Angioplasty - Articles on Medical Diseases and Conditions
Your doctor may prescribe medications such as nitroglycerin to relax the coronary arteries, calcium antagonists to guard against coronary artery spasm , or aspirin and other antiplatelet drugs to prevent blood clots in the area of the blockage. If you have a stent, you will have to take blood thinners (such as aspirin) inde?nitely. You will also take an antiplatelet such as clopidogrel at least one month after a bare-metal stent is placed in your artery and two or more years after a drug-eluting stent is placed in your artery. Because of the presence of the metal stent, you should not have magnetic resonance imaging (MRI) for at least 4 weeks with- out checking with your doctor ?rst. But you can go through a metal detector at an airport without a problem.. Restenosis. Restenosis (renarrowing or constriction) can occur in the same area of the blood vessel where your angioplasty was done, often within about 6 months of the original procedure. Although placement of a stent greatly reduces the ...
http://med-life.net/2009/08/05/angioplasty/
IP] Diagnosis date partyIP] Diagnosis date party
Jen Woodall wrote: , I strongly believe , that should be recognized in whatever way each person chooses. I always , acknowledge the date (well, close to it--cant always remember the exact , date) of my dx in some way. I know my diagnosis date EXACTLY, and I know exactly when my BGs started to go up, and I know when they went kablooie rapidly. I started to have problems in the summer of 1991; my BGs went kablooie starting on July 28, 1992, and I was officially diagnosed on Aug. 17, 1992 after landing in the hospital with a coronary artery spasm. Then they went back down again, and I was able to maintain on diet and exercise until the summer of 1993; in Sept. 1993, I went to the doc, and my BGs were once again rising rapidly, so she tried increasing doses and different sulfonylureas to no effect. I finally went on insulin on May 12, 1994, and THATs the date I celebrate! Like insulin gave me my life back, and I think THATs worth celebrating -- during my time on diet and orals, I was consistently ...
http://www.insulin-pumpers.org/mail/archive/mail-insulin-pumpers/Nov1999/msg02644.html
Heart Attack Causes: Coronary Heart Disease, Blood Clots & Artery Spasms - Columbia Asia Hospital - India
When plaque collects in the arteries, it can end up rupturing and cause blood clots to form. These blood clots further block the flow of oxygenated blood to the heart muscles. With time, this build up gets worse and prevents the flow to a point where the heart muscles are unable to get the necessary oxygenated blood ...
https://www.columbiaindiahospitals.com/health-articles/heart-attack-causes-coronary-heart-disease-blood-clots-artery-spasms
Diagnosis of coronary vasospasm in patients with clinical presentation of unstable angina pectoris using ergonovine...Diagnosis of coronary vasospasm in patients with clinical presentation of unstable angina pectoris using ergonovine...
TY - JOUR. T1 - Diagnosis of coronary vasospasm in patients with clinical presentation of unstable angina pectoris using ergonovine echocardiography. AU - Song, Jae Kwan. AU - Park, Seong Wook. AU - Kong, Duk Hyun. AU - Lee, Cheol Whan. AU - Choi, Kee Joon. AU - Hong, Myung Ki. AU - Kim, Jae Joong. AU - Kim, You Ho. AU - Park, Seung Jung. PY - 1998/12/15. Y1 - 1998/12/15. N2 - Although coronary vasospasm can contribute to the development of unstable angina, the definite diagnostic method has not been established. The purpose of this study was to determine if ergonovine echocardiography (detection of regional wall motion abnormality during bedside ergonovine challenge) after angiographic confirmation of insignificant fixed disease would be useful and safe in detecting coronary vasospasm in patients with unstable angina. After control of chest pain with medications in patients admitted to the coronary care unit under the tentative diagnosis of unstable angina, diagnostic coronary angiography was ...
https://yonsei.pure.elsevier.com/en/publications/diagnosis-of-coronary-vasospasm-in-patients-with-clinical-present
Coronary artery vasospasm in a patient with Churg-Strauss syndrome | Garvan Institute of Medical ResearchCoronary artery vasospasm in a patient with Churg-Strauss syndrome | Garvan Institute of Medical Research
Patients with Churg-Strauss syndrome often suffer from unusual cardiac manifestations and sudden cardiac death. This differs from patients with other autoimmune disorders, who typically present with premature ischaemic heart disease. We report the case of a 56-year-old man with recurrent coronary vasospasm, including an inferoposterior ST-elevation myocardial infarction, complicated by bradycardic arrest. There was only minor coronary artery disease on coronary angiography. An elevated eosinophil count was noted. His medical history included allergic rhinitis with polyposis, adult-onset asthma and biopsy-proven eosinophilic oesophagitis. Review of his sinus biopsies demonstrated blood vessels with marked accumulation of eosinophils in extravascular areas. The patient, therefore, met the American College of Rheumatology criteria for Churg-Strauss syndrome. The patient was commenced on immunosuppression, with the return of the eosinophil count to within normal limits, and remains free of cardiovascular
https://www.garvan.org.au/research/collaborative-programs/circa/publications/14778
Coronary Artery Spasm | Annals of Internal Medicine | American College of PhysiciansCoronary Artery Spasm | Annals of Internal Medicine | American College of Physicians
Coronary artery spasm is an important pathogenetic mechanism in some forms of myocardial ischemic disease. Factors that may be important in the genesis of spasm include the autonomic nervous system, prostaglandins, endoperoxides, thromboxanes, and the calcium availability to the contractile apparatus. Spasm results in myocardial ischemia with attendant chest pain and electrocardiographic and hemodynamic changes; it is the primary pathogenetic mechanism in Prinzmetals variant angina and has been found in association with classic angina pectoris and acute myocardial infarction. Diagnosis of coronary artery spasm is firmly made only by coronary angiography. Treatment includes the use of both short- and long-acting nitrates and the slow-channel blocking agents such as verapamil, nifedipine, and perhexiline. ...
http://annals.org/aim/article-abstract/693342/coronary-artery-spasm
Long-Term Prognosis of Vasospastic Angina without Significant Atherosclerotic Coronary Artery Disease<...
TY - JOUR. T1 - Long-Term Prognosis of Vasospastic Angina without Significant Atherosclerotic Coronary Artery Disease. AU - Egashira, Kcnsuke. AU - Kikuchi, Yutaka. AU - Sagara, Tomohiko. AU - Sugihara, Masayoshi. AU - Nakamura, Motoomi. PY - 1987/1/1. Y1 - 1987/1/1. N2 - Long-term prognosis of 90 patients with vasospastic angina without significant coronary artery disease (less than 50% reduction in luminal diameter) was examined for a mean follow-up period of 4 years. All patients had episodes of angina at rest and were treated with calcium antagonists. One patient developed myocardial infarction and 2 died suddenly during the follow-up period. In the patient with myocardial infarction, there was an abrupt worsening of angina prior to the infarction despite therapy with a calcium antagonist. One of the sudden death patients discontinued his calcium antagonist before his death. Of the sudden death patients, one had ventricular tachycardia and the other had a complete atrioventricular block ...
https://kyushu-u.pure.elsevier.com/ja/publications/long-term-prognosis-of-vasospastic-angina-without-significant-ath
US Patent for N-aminoalkylperfluoroalkanoylaminobenzene-sulfonamide anti-arrhythmic agents Patent (Patent # 4,794,196 issued...US Patent for N-aminoalkylperfluoroalkanoylaminobenzene-sulfonamide anti-arrhythmic agents Patent (Patent # 4,794,196 issued...
N-Aminoalkyl(perfluoroalkanoylaminophenyl)sulfonic acid amides of the formula: ##STR1## in which R.sup.1 is perfluoroalkanoylamino of 2 to 4 carbon atoms, in 3- or 4- position of the benzene ring;R.sup.2 is hydrogen or alkyl of 1 to 4 carbon atoms;R.sup.3 is hydrogen or straight or branched chain alkyl of 1 to 4 carbon atoms;R.sup.4 is straight or branched chain alkyl of 1 to 4 carbon atoms; andn is one of the integers 2, 3 or 4;or a pharmaceutically acceptable salt thereof, are Class I anti-arrhythmic agents useful in the treatment of cardiac arrhythmias and conditions characterized by coronary arteries vasospasm and myocardial ischemia.
https://patents.justia.com/patent/4794196
Everyday E(B)M: Emergency Department management of myasthenic crisisEveryday E(B)M: Emergency Department management of myasthenic crisis
Treatment in the emergency department should focus on frequent evaluation (e.g. every 2 hours) of the patients respiratory status with serial FVC and NIF and intubating promptly at signs of respiratory failure. Sitting the patient upright may help temporize the patients dyspnea while preparing for intubation. Even if not intubated, patients presenting with myasthenic crises will need admission to the ICU. First line therapies include IVIG and plasmapheresis, both of which take several days to reach full clinical effect by removing acetylcholine receptor antibodies from the circulation. High dose glucocorticoid therapy and other immunosuppresants such as azathioprine and cyclosporine can be initiated but are intended as long-term therapies and do not provide any benefit in the emergent setting. Anticholinesterase use, such as pyridostigmine, remains controversial because of the risk of coronary artery vasospasm (resulting in MI) and arrhythmia. A basic infectious workup, including a chest x-ray ...
https://wueverydayebm.blogspot.com/2014/08/emergency-department-management-of.html
Rho Kinase Inhibitors: Potential Treatments for Diabetes and Diabetic Complications | Bentham ScienceRho Kinase Inhibitors: Potential Treatments for Diabetes and Diabetic Complications | Bentham Science
Title:Rho Kinase Inhibitors: Potential Treatments for Diabetes and Diabetic Complications. VOLUME: 18 ISSUE: 20. Author(s):Hong Zhou and Yong-jun Li. Affiliation:Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.. Keywords:RhoA, Rho kinase, inhibitors, diabetes, complications, GTPase, hypertension, coronary vasospasm, stroke, atherosclerosis. Abstract:The small GTPase RhoA and its downstream effector, Rho kinase (ROCK), appear to mediate numerous pathophysiological signals, including smooth muscle cell contraction, actin cytoskeleton organization, cell adhesion and motility, proliferation, differentiation and the expression of several genes. Clinical interest in the RhoA/ROCK pathway has increased, due to emerging evidence that this signaling pathway is involved in the pathogenesis of several diseases, including hypertension, coronary vasospasm, stroke, atherosclerosis, heart failure and diabetes; ROCK is considered an important future ...
https://www.eurekaselect.com/98495/article?tracking-code=4
DI-fusion Coronary vasospasm after myocardial revascularisation...
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
http://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/164633/Details
COCHIN CARDIAC CLUB: October 2013COCHIN CARDIAC CLUB: October 2013
Chest pain following successful percutaneous coronary interventions is a common problem. Although the development of chest pain after coronary interventions may be of benign character, it is disturbing to patients, relatives and hospital staff. Such pain may be indicative of acute coronary artery closure, coronary artery spasm or myocardial infarction, but may also simply reflect local coronary artery trauma. The distinction between these causes of chest pain is crucial in selecting optimal care.Management of these patients may involve repeat coronary angiography and additional intervention. Commonly, repeat coronary angiography following percutaneous transluminal coronary angioplasty (PTCA) in patients with chest pain demonstrates widely patent lesion sites suggesting that the pain was due to coronary artery spasm, coronary arterial wall stretching or was of non-cardiac origin. ...
http://cochincardiacclub.blogspot.com/2013/10/
Efficacy Study of Atorvastatin to Treat Variant Angina - Full Text View - ClinicalTrials.govEfficacy Study of Atorvastatin to Treat Variant Angina - Full Text View - ClinicalTrials.gov
Vasospastic angina is presented by myocardial ischemia with spasm of coronary artery accompanying chest pain or discomfort. The precise mechanisms have not been established, but a reduction in NO (nitric oxide) production, an imbalance between endothelium-derived relaxing and contracting factors,or an injury of endothelium have been suggested.. Impaired FMD(flow mediated endothelium-dependent vasodilation) in the brachial artery was demonstrated in vasospastic angina,and improvement of endothelial dysfunction with treatment of statin is documented in several studies.. So, we expect that statin treatment for vasospastic angina provide additional therapeutic effects via improvement of endothelial dysfunction. ...
https://clinicaltrials.gov/ct2/show/NCT00620204
Ischemic Heart Disease in Women | JACC: Cardiovascular ImagingIschemic Heart Disease in Women | JACC: Cardiovascular Imaging
The decades-long research focus on the pathophysiology of coronary artery disease (CAD) has provided insights into sex-specific factors that are uniquely important in the noninvasive diagnosis of myocardial ischemic syndromes in women. Evidence gained from the landmark WISE (Womens Ischemic Syndrome Evaluation) study (1) indicates that the full spectrum of CAD in women extends beyond atherosclerotic stenoses in the epicardial coronary arteries to include dysfunction of the coronary microvasculature and endothelium. Additional conditions contributing to the full pathophysiologic spectrum of acute and chronic ischemic heart disease (IHD) in women include coronary vasospasm and coronary artery dissection which mainly affect the epicardial coronary arteries and often develop in younger women (2). The implications of these diverse conditions are substantial. They create diagnostic challenges and limit the application of traditional testing strategies which, while adequate to detect obstructive ...
http://imaging.onlinejacc.org/content/9/4/347
What is Acute Myocardial Infarction | kenyaconfidential.comWhat is Acute Myocardial Infarction | kenyaconfidential.com
Acute myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide. Myocardial infarction occurs when myocardial ischemia, a diminished blood supply to the heart, exceeds a critical threshold and overwhelms myocardial cellular repair mechanisms designed to maintain normal operating function and homeostasis. Ischemia at this critical threshold level for an extended period results in irreversible myocardial cell damage or death.. Critical myocardial ischemia can occur as a result of increased myocardial metabolic demand, decreased delivery of oxygen and nutrients to the myocardium via the coronary circulation, or both. An interruption in the supply of myocardial oxygen and nutrients occurs when a thrombus is superimposed on an ulcerated or unstable atherosclerotic plaque and results in coronary occlusion.1 A high-grade (,75%) fixed coronary artery stenosis caused by atherosclerosis or a dynamic stenosis associated with coronary vasospasm can also limit the supply of ...
http://kenyaconfidential.com/2017/07/11/what-is-acute-myocardial-infarction/
Attenuation of endothelium-related relaxation and enhanced responsiveness of vascular smooth muscle to histamine in spastic...
TY - JOUR. T1 - Attenuation of endothelium-related relaxation and enhanced responsiveness of vascular smooth muscle to histamine in spastic coronary arterial segments from miniature pigs. AU - Yamamoto, Y.. AU - Tomoike, H.. AU - Egashira, K.. AU - Nakamura, M.. PY - 1987/1/1. Y1 - 1987/1/1. N2 - Mechanism of coronary spasm was examined regarding endothelium-related relaxation and contraction produced by smooth muscle cells of spastic vessels isolated from Gottingen miniature pigs. In these pigs, coronary artery spasm was documented angiographically in vivo three months after endothelial denudation, and spastic and control segments of the coronary artery were suspended in organ chambers at their optimal length for generating tension. Applications of KCl (118 mM), acetylcholine (10-9 to 10-4 M), and PGF(2α) (10-8 to to 3 x 10-5 M) produced similar tension, at the respective doses, in both the spastic and control coronary arteries. During increasing concentrations of histamine (10-8 to 3 x 10-4 ...
https://kyushu-u.pure.elsevier.com/en/publications/attenuation-of-endothelium-related-relaxation-and-enhanced-respon
BMJ Best PracticeBMJ Best Practice
Acute coronary syndrome (ACS) refers to acute myocardial ischemia caused by atherosclerotic coronary disease, and includes ST elevation myocardial infarction (STEMI), non-ST elevation MI (NSTEMI), and unstable angina. Cocaine accounts for up to 25% of acute MIs in people ages 18 to 45 years. [9] Qureshi AI, Suri MF, Guterman LR, et al. Cocaine use and the likelihood of nonfatal myocardial infarction and stroke: data from the Third National Health and Nutrition Examination Survey. Circulation. 2001;103:502-506. http://circ.ahajournals.org/content/103/4/502 http://www.ncbi.nlm.nih.gov/pubmed/11157713?tool=bestpractice.com The lifetime risk of nonfatal MI with cocaine use is 7 times the risk in nonusers. In the hour after cocaine is used, the risk of MI is 24 times the baseline risk. It is probably due to cocaine-induced coronary vasospasm and thrombosis, in addition to a direct effect on heart rate and arterial pressure. Cocaine also has direct myocardial toxic properties. [10] Amsterdam EA, ...
http://bestpractice.bmj.com/topics/en-us/986
Myocardial Infarction in Childhood Workup: Laboratory Studies, Radiography, EchocardiographyMyocardial Infarction in Childhood Workup: Laboratory Studies, Radiography, Echocardiography
Acute myocardial infarction (AMI) is rare in childhood and adolescence. Although adults acquire coronary artery disease (CAD) from lifelong deposition of atheroma and plaque, which causes coronary artery spasm and thrombosis, children usually have either an acute inflammatory condition of the coronary arteries or an anomalous origin of the le...
https://emedicine.medscape.com/article/897453-workup
A simple fix to avoid unnecessary coronary stents is overlooked by cardiologists and current cardiovascular guidelines |...
Physician researchers suspect that some cases of coronary artery spasm go unrecognized and are incorrectly treated with stents. The good news - there could be a simple fix to eliminate these unnecessary stenting procedures ...
http://www.universefirefox.com/a-simple-fix-to-avoid-unnecessary-coronary-stents-is-overlooked-by-cardiologists-and-current-cardiovascular-guidelines/
tylenol 3 weight loss
Regularly, hpv warts Regularly, hpv warts probably go away in an instant as well as come met potently without needing to do any scars vs sustained negative effects. Even so , on occasion, so what seems to be a growth stands out as the start of a make of cancer, that is why men and women who are certainly protected from session really needs to be come across by way of medical professional. Repetitive venereal blemishes genuinely harsh peculiar in percocet coronary artery spasm addition to the open healthiness focus. Even while genital hpv warts are easy to remove, the unique trojan viruses the tl901 same consistently functioning. Certain forms of HPV will certainly deliver muscle tissue adjustments to the main uterine cervix of ladies causing recurrent deseases that may possibly mean cervical health problems. The primary recommendation for ladies that has a credibility wonderful penile blemishes is usually to receive the companys health each single only 6 months just for nipple smears to keep ...
http://e9alendronate70mg.aircus.com
discovered - Blogoved for Healthy
Ulcerative colitis is a crucial well being condition involving irritation, ulceration, and bleeding of the colon. Its thought-about to be an auto-immune situation for which standard medication has no treatment. The affected particular person is given steroids and different medication to manage flare-ups and bleeding. The one remedy is to remove the affected person colon. This disease can both be minor with occasional flare-ups or debilitating and severe. The interior bleeding may cause extreme anemia. Diarrhea could cause an absence of fluids and electrolytes. The ache from intestinal spasms may very well be extreme. It might truly get to the … Read the rest ...
http://blogoved.net/tag/discovered
Nicardipine - Dagan Summary Report | CureHunterNicardipine - Dagan Summary Report | CureHunter
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
http://www.curehunter.com/public/keywordSummaryD009529.do
Chest pain mostly when Im laying down - Heart Disease - MedHelpChest pain mostly when Im laying down - Heart Disease - MedHelp
Hello, Im a 23-year old female. I will start off by telling you when this started and what was happening. It was January of 2005, I had my 2nd child in December of 2004. I started having chest pain at...
https://www.medhelp.org/posts/Heart-Disease/Chest-pain-mostly-when-Im-laying-down/show/10885
Facial Problems, NoninjuryFacial Problems, Noninjury
The more of these symptoms you have, the more likely it is that youre having a heart attack. Chest pain or pressure is the most common symptom, but some people, especially women, may not notice it as much as other symptoms. You may not have chest pain at all but instead have shortness of breath, nausea, or a strange feeling in your chest or other areas.. ...
https://www.billingsclinic.com/health-info/library/document-viewer/?id=facpn
SaraTGSaraTG
sharp chest pains at 20? Hello..I won`t attempt to tell you what`s actually wrong with you as I`d just be guessing..But I have had similar experiences twice in my life..The first was when I was in my late 20`s..I`d get those.... ...
https://www.healingwell.com/community/profile.aspx?f=42&m=307895&p=18976
Newest Articles | JGPNewest Articles | JGP
A CONTRIBUTION TO THE COMPARATIVE STUDY OF THE ORIGIN OF THE SYMPATHETIC AND THE ADRENALIN-SECRETING SYSTEMS AND OF THE VASCULAR MUSCLES WHICH THEY REGULATE. ...
http://jgp.rupress.org/newest?field_highwire_a_collections_tid=All&field_highwire_a_epubdate_value%5Bvalue%5D&page=867
John Thompson ShepherdJohn Thompson Shepherd
Shepherd, J.; Katusic, Z. S.; Vedernikov, Y.; Vanhoutte, P. M. (1991). "Mechanisms of coronary vasospasm: Role of endothelium ... "Inhibitory Role of the Endothelium in the Response of Isolated Coronary Arteries to Platelets". Science. 221 (4607): 273-274. ...
https://en.wikipedia.org/wiki/John_Thompson_Shepherd
Chest painChest pain
Prinzmetal's angina: Chest pain is caused by coronary vasospasm. More common in women younger than 50 years. Person usually ... Less than 20% of all cases of chest pain admissions are found to be due to coronary artery disease. The rate of chest pain as a ... If acute coronary syndrome ("heart attack") is suspected, many people are admitted briefly for observation, sequential ECGs, ... Acute coronary syndrome Stable or unstable angina Myocardial infarction ("heart attack"): People usually complained of a ...
https://en.wikipedia.org/wiki/Chest_pain
NicorandilNicorandil
Angina commonly arises from vasospasm of the coronary arteries. There are multiple mechanisms causing the increased smooth ... Overall, this leads to relaxation of the smooth muscle and coronary vasodilation. The effect of nicorandil as a vasodilator is ... Lower levels of nitric oxide are present in spastic coronary arteries. L-type calcium channel expression increases in spastic ... In humans, the nitrate action of nicorandil dilates the large coronary arteries at low plasma concentrations. At high plasma ...
https://en.wikipedia.org/wiki/Nicorandil
FrovatriptanFrovatriptan
These include: coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia and ...
https://en.wikipedia.org/wiki/Frovatriptan
ATP-sensitive potassium channelATP-sensitive potassium channel
Chutkow WA, Pu J, Wheeler MT, Wada T, Makielski JC, Burant CF, McNally EM (July 2002). "Episodic coronary artery vasospasm and ... and deletion of the kir6.2 or sur2 genes leads to coronary artery vasospasm and death. Upon further exploration of sarcKATP's ...
https://en.wikipedia.org/wiki/ATP-sensitive_potassium_channel
MigraineMigraine
They can cause vasospasm including coronary vasospasm and are contraindicated in people with coronary artery disease. Magnesium ...
https://en.wikipedia.org/wiki/Migraine
SumatriptanSumatriptan
Events reported have included coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular ...
https://en.wikipedia.org/wiki/Sumatriptan
Takotsubo cardiomyopathyTakotsubo cardiomyopathy
... the idea of coronary artery vasospasm is still believed to contribute to the TTS disease process. The theory of vasospasm is ... Research supports the widely-held understanding that microvascular dysfunction and coronary vasospasm caused by a rapid influx ... It has been noted that when there are vasospasms, even in multiple arteries, that they do not correlate with the areas of ... It is likely that there are multiple factors at play that could include some amount of vasospasm and failure of the ...
https://en.wikipedia.org/wiki/Takotsubo_cardiomyopathy
ErgotamineErgotamine
At higher doses, it can cause raised arterial blood pressure, vasoconstriction (including coronary vasospasm) and bradycardia ... Contraindications include: atherosclerosis, Buerger's syndrome, coronary artery disease, hepatic disease, pregnancy, pruritus, ...
https://en.wikipedia.org/wiki/Ergotamine
George BillmanGeorge Billman
In a 1995 review article, he said resulting secondary effects include arrhythmia, coronary vasospasm, myocardial infarction, ... the left main anterior coronary artery is surgically blocked and a hydraulic cuff is placed around the left circumflex coronary ...
https://en.wikipedia.org/wiki/George_Billman
List of examples of Stiglers lawList of examples of Stigler's law
Prinzmetal angina: also known as variant angina, referring to angina (chest pain) caused by vasospasm of the coronary arteries ...
https://en.wikipedia.org/wiki/List_of_examples_of_Stigler's_law
DihydroergotamineDihydroergotamine
DHE and triptans should never be taken within 24 hours of each other due to the potential for coronary artery vasospasm.[ ... coronary, cerebral, and peripheral vascular disease, hypersensitivity reactions, sepsis, and uncontrolled hypertension. ...
https://en.wikipedia.org/wiki/Dihydroergotamine
TroponinTroponin
This can also occur in people with coronary vasospasm, a type of myocardial infarction involving severe constriction of the ... 2001). "Acute coronary syndromes. The diagnostic role of troponins". Thromb. Res. 103 (1): 63-69. CiteSeerX 10.1.1.500.6908. ... Zethelius B, Johnston N, Venge P (February 2006). "Troponin I as a predictor of coronary heart disease and mortality in 70-year ... October 1996). "Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes ...
https://en.wikipedia.org/wiki/Troponin
András RosztóczyAndrás Rosztóczy
The role of esophagocardiac reflex in the pathogenesis of coronary vasospasm: a case report. Z Gastroenterol. 2003; 41: 455(A ...
https://en.wikipedia.org/wiki/András_Rosztóczy
Cardiac arrestCardiac arrest
Coronary vasospasm may result in cardiac arrhythmias, altering the heart's electrical conduction with a risk of complete ... inflammation known as coronary arteritis, embolism, vasospasm, and mechanical abnormalities related to connective tissue ... 829 Abnormalities of the coronary arteries not related to atherosclerosis include congenital coronary artery anomalies (most ... Current cigarette smokers with coronary artery disease were found to have a two to threefold increase in the risk of sudden ...
https://en.wikipedia.org/wiki/Cardiac_arrest
Variant anginaVariant angina
... is caused by vasospasm, a narrowing of the coronary arteries due to contraction of the heart's smooth muscle ... The mechanism that causes such intense vasospasm, as to cause a clinically significant narrowing of the coronary arteries is so ... Heberden in that it appeared due to episodic vasospasm of coronary arteries that were typically not occluded by pathological ... Eosinophilic coronary periarteritis: a very rare form of coronary artery spasm; it is due to non-allergic infiltration of ...
https://en.wikipedia.org/wiki/Variant_angina
Kounis syndromeKounis syndrome
In addition, beta-blockers can increase coronary vasospasm and ischemia. Opiates should be used with caution. In addition to ... Coronary stenting, a common procedure used in coronary artery disease patients has also been found to be a cause. Environmental ... These mediators can precipitate coronary artery spasm and accelerate the rupture of atheromatous plaques of the coronary ... SPECT have revealed severe myocardial ischemia while coronary angiography showed normal coronary arteries. Furthermore, with ...
https://en.wikipedia.org/wiki/Kounis_syndrome
Sy MahSy Mah
... coronary vasospasm] without angina." Autopsy revealed localized fibrosis of the left papillary muscles, but no evidence of ... Rowe, William J. (May 1991). "A World Record Marathon Runner with Silent Ischemia without Coronary Atherosclerosis". Chest. 99 ... coronary atherosclerosis. Mah has been described as "an early leader of the modern running boom". Joe Henderson wrote an ...
https://en.wikipedia.org/wiki/Sy_Mah
AntianginalAntianginal
... directly preventing coronary artery vasospasm). They are not used in the treatment of unstable angina . In vitro, they dilate ... Pfister M, Seiler C, Fleisch M, Göbel H, Lüscher T, Meier B (October 1998). "Nitrate induced coronary vasodilatation: ... reducing heart rate and improving coronary blood flow. In vivo, the vasodilation and hypotension trigger the baroreceptor ... the coronary and peripheral arteries and have negative inotropic and chronotropic effects - decreasing afterload, improving ...
https://en.wikipedia.org/wiki/Antianginal
Thomas LüscherThomas Lüscher
... coronary artery disease, cerebral vasospasm and diabetic vascular disease. There he worked with Paul M. Vanhoutte and was ... Coronary artery graft disease: mechanisms and prevention. Berlin: Springer-Verlag. 1994. ISBN 978-3-540-57438-5. OCLC 30319185 ... "Dark Chocolate Improves Coronary Vasomotion and Reduces Platelet Reactivity". Circulation. 116 (21): 2376-2382. doi:10.1161/ ...
https://en.wikipedia.org/wiki/Thomas_Lüscher
Sneddons syndromeSneddon's syndrome
... severe but transient neurological symptoms thought to be caused by cerebral vasospasm, coronary disease and early-onset ... coronary disease and dementia. The skin manifestations may precede the neurologic symptoms by years. Sneddon's syndrome is a ...
https://en.wikipedia.org/wiki/Sneddon's_syndrome
Calcium channel blockerCalcium channel blocker
... reduce myocardial oxygen demand and reverse coronary vasospasm, and are often used to treat angina. They have minimal ... to prevent peripheral and cerebral vasospasm, and to reduce chest pain caused by angina pectoris. N-type, L-type, and T-type ... This substance can pass the blood-brain barrier and is used to prevent cerebral vasospasm. Nisoldipine (Baymycard, Sular, ...
https://en.wikipedia.org/wiki/Calcium_channel_blocker
Renal anginaRenal angina
Unlike angina pectoris, commonly caused due to ischemia of the heart muscle secondary to coronary artery occlusion or vasospasm ... Like acute coronary syndrome which precedes or is a sign of a heart attack, renal angina is used as a herald sign for a kidney ... revolutionized the survival for acute coronary syndrome (ACS). Without correct context, the performance of troponin for ...
https://en.wikipedia.org/wiki/Renal_angina
VasospasmVasospasm
Ischemia in the heart due to prolonged coronary vasospasm can lead to angina, myocardial infarction and even death. Vasospasm ... Regarding coronary vasospasm, one surgical intervention, referred to as percutaneous coronary intervention or angioplasty, ... Another surgical intervention is coronary artery bypass. Coronary artery vasospasm Raynaud's phenomenon, a vasospastic disorder ... Vasospasm typically appears 4 to 10 days after subarachnoid hemorrhage. Along with physical resistance, vasospasm is a main ...
https://en.wikipedia.org/wiki/Vasospasm
Coronary catheterizationCoronary catheterization
... coronary vasospasm) The patient being examined or treated is usually awake during catheterization, ideally with only local ... A coronary catheterization is a minimally invasive procedure to access the coronary circulation and blood filled chambers of ... that coronary catheterization does not allow the recognition of the presence or absence of coronary atherosclerosis itself, ... Coronary artery luminal narrowing reduces the flow reserve for oxygenated blood to the heart, typically producing intermittent ...
https://en.wikipedia.org/wiki/Coronary_catheterization
Coronary vasospasmCoronary vasospasm
Angina due to coronary vasospasm is also known as variant angina. Hung, Ming-Jui; Hu, Patrick; Hung, Ming-Yow (2014). "Coronary ... Coronary vasospasm refers to when a coronary artery suddenly undergoes either complete or sub-total temporary occlusion. In ... Due to the challenge of capturing episodes of coronary vasospasm spontaneously, provocative testing to induce coronary ... When coronary vasospasm causes an artery to undergo complete occlusion, an EKG might show evidence of ST-segment elevation in ...
https://en.wikipedia.org/wiki/Coronary_vasospasm
Cardiac catheterizationCardiac catheterization
... coronary vasospasm) Right heart catheterization, along with pulmonary function testing and other testing should be done to ... Coronary angiography is a diagnostic procedure that allows visualization of the coronary vessels. Fluoroscopy is used to ... A common example of cardiac catheterization is coronary catheterization that involves catheterization of the coronary arteries ... Acute coronary syndromes: ST elevation MI (STEMI), non-ST Elevation MI (NSTEMI), and unstable angina Evaluation of coronary ...
https://en.wikipedia.org/wiki/Cardiac_catheterization
DiltiazemDiltiazem
Variant angina - it is effective owing to its direct effects on coronary dilation. Unstable angina (preinfarction, crescendo ... diltiazem may be particularly effective if the underlying mechanism is vasospasm. Myocardial bridge Dysmenorrhea For ... Diltiazem is indicated for: Stable angina (exercise-induced) - diltiazem increases coronary blood flow and decreases myocardial ... Narimatsu A, Taira N (August 1976). "Effects of atrio-ventricular conduction of calcium-antagonistic coronary vasodilators, ...
https://en.wikipedia.org/wiki/Diltiazem
Chest pain in childrenChest pain in children
... effusion Coronary artery disease Kawasaki disease Premature arterial sclerosis Structural associations Arterial vasospasm ... the sudden death of a family member under 35 years-old the early onset in a family member of coronary artery disease a family ... Cocaine/marijuana toxicity and induced vasospasm Hypertrophic cardiomyopathy Valvular stenosis Mitral valve prolapse Aortic ...
https://en.wikipedia.org/wiki/Chest_pain_in_children
Ischemic cardiomyopathyIschemic cardiomyopathy
"Coronary artery bypass with ventricular restoration is superior to coronary artery bypass alone in people with ischemic ... The following are causes of ischemic cardiomyopathy: Diabetes Atherosclerosis Vasospasm Inflammation of arteries Ischemic ... Ischemic cardiomyopathy is a type of cardiomyopathy caused by a narrowing of the coronary arteries which supply blood to the ... A 2004 study showed the patients in that study who underwent ventricular restoration as well as a coronary artery bypass ...
https://en.wikipedia.org/wiki/Ischemic_cardiomyopathy
Complications of hypertensionComplications of hypertension
In the initial, vasoconstrictive stage, there is vasospasm and an increase in retinal arteriolar tone owing to local ... It is an independent predisposing factor for heart failure, coronary artery disease, stroke, kidney disease, and peripheral ... abnormalities of blood flow due to atherosclerotic coronary artery disease and microvascular disease, and cardiac arrhythmias. ...
https://en.wikipedia.org/wiki/Complications_of_hypertension
VerapamilVerapamil
Calcium channel blockers like verapamil dilate the coronary blood vessels, which increases the supply of blood and oxygen to ... Verapamil is also used intra-arterially to treat cerebral vasospasm. Verapamil is used to treat the condition cluster headache ... November 2010). "Endovascular treatment of medically refractory cerebral vasospasm following aneurysmal subarachnoid hemorrhage ...
https://en.wikipedia.org/wiki/Verapamil
ErgometrineErgometrine
It can induce spasm of the coronary arteries. It is used to diagnose variant (Prinzmetal's) angina. Possible side effects ... Anthony's fire": prolonged vasospasm resulting in gangrene and amputations; hallucinations and dementia; and abortions. ... Romagnoli E, Niccoli G, Crea F (October 2005). "Images in cardiology: A coronary organic stenosis distal to severe, ergonovine ... Sunagawa O, Shinzato Y, Touma T, Tomori M, Fukiyama K (May 2000). "Differences between coronary hyperresponsiveness to ...
https://en.wikipedia.org/wiki/Ergometrine
Unstable anginaUnstable angina
It is also classified as a type of acute coronary syndrome (ACS). It can be difficult to distinguish unstable angina from non- ... pectoris caused by disruption of an atherosclerotic plaque with partial thrombosis and possibly embolization or vasospasm ... 2016). "2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment ... elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment ...
https://en.wikipedia.org/wiki/Unstable_angina
Endoscopic thoracic sympathectomyEndoscopic thoracic sympathectomy
"Effect of chemical sympathectomy on coronary flow and cardiovascular adjustment to exercise in dogs". Pflügers Archiv. 341 (4 ... "Effects of cervical sympathectomy on vasospasm induced by meningeal haemorrhage in rabbits". Arquivos de Neuro-Psiquiatria. 64 ...
https://en.wikipedia.org/wiki/Endoscopic_thoracic_sympathectomy
Coronary Artery Vasospasm: Background, Etiopathophysiology, EpidemiologyCoronary Artery Vasospasm: Background, Etiopathophysiology, Epidemiology
... or smooth muscle constriction of the coronary artery, is an important cause of chest pain syndromes that can lead to myocardial ... encoded search term (Coronary Artery Vasospasm) and Coronary Artery Vasospasm What to Read Next on Medscape ... mechanisms of coronary artery vasospasm include enhanced phospholipase C activity. [11] In addition, coronary artery vasospasm ... Coronary artery vasospasm, or smooth muscle constriction of the coronary artery, is an important cause of chest pain syndromes ...
https://www.medscape.com/answers/153943-103023/what-is-coronary-artery-vasospasm
Coronary Artery Vasospasm Differential DiagnosesCoronary Artery Vasospasm Differential Diagnoses
... or smooth muscle constriction of the coronary artery, is an important cause of chest pain syndromes that can lead to myocardial ... encoded search term (Coronary Artery Vasospasm) and Coronary Artery Vasospasm What to Read Next on Medscape ... Coronary artery vasospasm is an important cause of chest pain but not the exclusive cause. Atherosclerotic coronary disease is ... Coronary Artery Vasospasm Differential Diagnoses. Updated: Nov 14, 2018 * Author: Stanley S Wang, JD, MD, MPH; Chief Editor: ...
https://emedicine.medscape.com/article/153943-differential
PCI complications: coronary vasospasm - wikidocPCI complications: coronary vasospasm - wikidoc
Multivessel coronary spasm involves several coronary arteries.[1][2] Pathophysiology. *Coronary vasospasm can be induced by PCI ... Coronary vasospasm can occasionally be induced by PCI.. *Rotablator cases are more prone to coronary vasospasm. The reported ... Smoking is a risk factor for coronary vasospasm. Natural History, Complications and Prognosis. *Coronary vasospasm can lead to ... Catheter-induced coronary vasospasm is usually short-lived.. *Catheter-induced coronary vasospasm is most prone to occur at the ...
https://www.wikidoc.org/index.php/PCI_in_the_Patient_with_Coronary_Vasospasm
What Is Coronary Vasospasm? | UPMC HealthBeatWhat Is Coronary Vasospasm? | UPMC HealthBeat
What Is Coronary Vasospasm?. Coronary vasospasm is the sudden narrowing of the coronary arteries-the blood vessels that supply ... Who Is at Risk for Coronary Vasospasm?. Coronary vasospasm can happen to anyone, but your overall heart health and lifestyle ... such as coronary vasospasm.. Diagnosing Coronary Vasospasm. Our specialists at the Magee-Womens Heart Program are here to help ... coronary vasospasm. Your doctor may perform a coronary angiogram to take images of your coronary arteries, which allows them to ...
https://share.upmc.com/2022/03/what-is-coronary-vasospasm/?source=archive_thumbnail-image
IMSEAR at SEARO: Diagnosis and management of coronary vasospasm.
Diagnosis and management of coronary vasospasm. Journal of the Association of Physicians of India. 1981 Jan; 29(1): 29-38. ...
https://imsear.searo.who.int/handle/123456789/94176
Flow-induced coronary vasospasm in diabetic patients - Augusta University Research Profiles
... pressurized coronary arteries and coronary endothelial cells in culture. Moreover, flow-induced changes in endothelial [Ca2+]i ... To test these hypotheses, I aim to isolate small coronary vessels from the (discarded) atrial appendages of patients with T2-DM ... Preliminary observations related to this application led to my main hypothesis that small coronary arteries of diabetic ... Using small vessel pressure myography and videomicroscopy, diameter changes of the isolated, coronary arteriole (, 100 5m) ...
https://augusta.pure.elsevier.com/en/projects/flow-induced-coronary-vasospasm-in-diabetic-patients-2
Refractory Ventricular Tachycardia From Coronary Vasospasm During Pregnancy | Ochsner JournalRefractory Ventricular Tachycardia From Coronary Vasospasm During Pregnancy | Ochsner Journal
She had a history of anxiety, depression, and angiography-documented coronary vasospasm in multiple coronary territories. Prior ... but how these changes affect the spasticity of coronary arteries in patients predisposed to vasospasm is unknown. Vasospasm ... Background: Coronary vasospasm leading to variant angina is uncommon, and the condition is rare in pregnant patients. Many ... Refractory Ventricular Tachycardia From Coronary Vasospasm During Pregnancy Message Subject (Your Name) has sent you a message ...
https://www.ochsnerjournal.org/content/19/4/401
Nitrate/Nitrite Toxicity: Literature Cited | Environmental Medicine | ATSDRNitrate/Nitrite Toxicity: Literature Cited | Environmental Medicine | ATSDR
Acute myocardial infarction secondary to coronary vasospasm during withdrawal from industrial nitroglycerin exposure - a case ...
https://www.atsdr.cdc.gov/csem/nitrate-nitrite/literature.html
Vasospastic AnginaVasospastic Angina
Coronary, Artery Vasospasms, Coronary, Coronary Artery Vasospasms, Coronary Vasospasm, Coronary Vasospasms, Vasospasm, Coronary ... Vasospasm, Coronary Artery, Vasospasms, Coronary, Vasospasms, Coronary Artery, CORONARY ARTERY SPASM, CORONARY SPASM, Coronary ... coronary, artery coronary spasms, coronary vasospasm, artery coronary spasm, coronary spasms, spasm coronary artery, vasospasm ... coronary, coronary artery vasospasm, coronary spasm, arteriospasm coronary, coronaries spasm, Coronary artery spasm, Coronary ...
https://fpnotebook.com/legacy/CV/CAD/VspstcAngn.htm
Krishnan BS - Search Results - PubMedKrishnan BS - Search Results - PubMed
Acute coronary vasospasm during thoracic spine surgery. Krishnan BS, Eipe N, Korula G. Krishnan BS, et al. J Neurosurg ...
https://pubmed.ncbi.nlm.nih.gov/?term=Krishnan+BS&cauthor_id=15787924
Pimiento: MedlinePlus suplementosPimiento: MedlinePlus suplementos
Akcay, A. B., Ozcan, T., Seyis, S., and Acele, A. Coronary vasospasm and acute myocardial infarction induced by a topical ... Nitric-oxide mediated effects of transdermal capsaicin patches on the ischemic threshold in patients with stable coronary ...
https://medlineplus.gov/spanish/druginfo/natural/945.html
DailyMed - DIHYDROERGOTAMINE MESYLATE NASAL spray, meteredDailyMed - DIHYDROERGOTAMINE MESYLATE NASAL spray, metered
Sumatriptan has been reported to cause coronary artery vasospasm, and its effect could be additive with dihydroergotamine ... Dihydroergotamine mesylate nasal spray may cause coronary artery vasospasm; patients who experience signs or symptoms ... Events reported have included coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular ... or to patients who have clinical symptoms or findings consistent with coronary artery vasospasm including Prinzmetals variant ...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ed1b7598-1778-4c0e-abe0-1ee96c728aac
Can monkeypox infection lead to myocarditis?Can monkeypox infection lead to myocarditis?
A coronary angiogram did not indicate coronary artery disease or any signs of vasospasm. ... Coronary Angiogram, Coronary Artery Disease, Coronavirus, covid-19, C-Reactive Protein, Diagnostic, Echocardiogram, Edema, ...
https://www.news-medical.net/news/20221113/Can-monkeypox-infection-lead-to-myocarditis.aspx
Imitrex Statdose Side Effects: Common, Severe, Long Term - Drugs.comImitrex Statdose Side Effects: Common, Severe, Long Term - Drugs.com
Frequency not reported: Abdominal aortic aneurysm, angina, atherosclerosis, cerebrovascular lesion, coronary artery vasospasm, ... Willett F, Curzen N, Adams J, Armitage M "Coronary vasospasm induced by subcutaneous sumatriptan." BMJ 304 (1992): 1415 ... Mueller L, Gallagher RM, Ciervo CA "Vasospasm-induced myocardial infarction with sumatriptan." Headache 36 (1996): 329-31 ...
https://www.drugs.com/sfx/imitrex-statdose-side-effects.html
Dilated Cardiomyopathy: Practice Essentials, Background, PathophysiologyDilated Cardiomyopathy: Practice Essentials, Background, Pathophysiology
... coronary vasospasm, and myocarditis. [23] ... Coronary blood flow may also be impaired by hypotension and ... Anthracyclines can also be associated with acute coronary spasm. The acute toxicity can occur at any point from the onset of ... Cardiac rehabilitation and survival in older coronary patients. J Am Coll Cardiol. 2009 Jun 30. 54(1):25-33. [QxMD MEDLINE Link ... Percutaneous trans-coronary-venous transplantation of autologous skeletal myoblasts in the treatment of post-infarction ...
https://emedicine.medscape.com/article/152696-overview
Zomig, Zomig Rapimelt (zolmitriptan) dosing, indications, interactions, adverse effects, and moreZomig, Zomig Rapimelt (zolmitriptan) dosing, indications, interactions, adverse effects, and more
Coronary artery vasospasm, myocardial infarction, transient ischemia, ventricular tachycardia/fibrillation, cardiac arrest, and ... Coronary artery disease. *Not for administration to patients with risk factors for coronary artery disease (CAD), including ... Additive vasospasm. Sep. by 24h.Monitor Closely (1)almotriptan and zolmitriptan both increase serotonin levels. Use Caution/ ... Additive vasospasm. Sep. by 24h.Monitor Closely (1)eletriptan and zolmitriptan both increase serotonin levels. Use Caution/ ...
https://reference.medscape.com/drug/zomig-zmt-zolmitriptan-343036
Find Research outputs - Mayo Clinic
Table of Contents page: American Journal of Cardiology
TCT-425: Comparison Of Incidence Of Coronary Vasospasm After Stent Deployment Among Cypher, Taxus, And Bare Metal Stents At ... Vessel Response of the Low-Dose Paclitaxel-Eluting Coronary Stent System with Biodegradable Coating in de novo Coronary lesions ... TCT-423: Comparison of Long Term Outcomes After Coronary Stenting in the Bare Metal Stent and Drug Eluting Stent Eras. ... TCT-420: Diabetes and Multivessel Coronary Disease. Impact of Drug Eluting Stents in a Non Selected Cohorte of Patients. ...
https://www.ajconline.org/issue/S0002-9149
Pain Management in Dentistry: Overview, Pain Definitions, Current Knowledge of Pain MechanismsPain Management in Dentistry: Overview, Pain Definitions, Current Knowledge of Pain Mechanisms
58] as well conditions such as untreated coronary vasospasm and refractory angina. [59] ...
https://reference.medscape.com/article/2066114-overview
Almotriptan Dosage & Rx Info | Uses, Side EffectsAlmotriptan Dosage & Rx Info | Uses, Side Effects
Ischemic heart disease (eg, angina pectoris, silent ischemia, history of MI). Coronary artery vasospasm (eg, Prinzmetals ... and consider monitoring ECG in patients with likelihood of unrecognized coronary artery disease (eg, postmenopausal women, men ...
https://www.empr.com/drug/almotriptan/
Difference Between Pericarditis and Stemi | Difference BetweenDifference Between Pericarditis and Stemi | Difference Between
However, cocaine use can also trigger STEMI because of coronary vasospasm.. Summary. The points of difference between ... It is commonly caused by an acute occlusion (the blockage of a blood vessel or hollow organ) of a coronary blood vessel ...
http://www.differencebetween.net/science/health/difference-between-pericarditis-and-stemi-2/
Perioperative thromboxane and cardiac patientsPerioperative thromboxane and cardiac patients
Vanhoutte, PM, Shimokawa, H. (1989) Endothelium-derived relaxing factor and coronary vasospasm. Circulation 80, 1-9. ... or previous coronary artery bypss grafting (CABG) or pericutaneous transluminal coronary angioplasty (PTCA). Patients at risk ... Plasma levels of TXB2 were determined in 40 patients at risk for, or with definite coronary artery disease. Blood sampling was ... Subjects were included in the study according to the presence of definite coronary artery disease (CAD) or were at risk for it ...
https://www.priory.com/med/thromboxane.htm
Capsicum: Health Benefits, Side Effects, Uses, Dose & PrecautionsCapsicum: Health Benefits, Side Effects, Uses, Dose & Precautions
Akcay, A. B., Ozcan, T., Seyis, S., and Acele, A. Coronary vasospasm and acute myocardial infarction induced by a topical ... Nitric-oxide mediated effects of transdermal capsaicin patches on the ischemic threshold in patients with stable coronary ...
https://www.rxlist.com/capsicum/supplements.htm
Ondansetron (ondansetron hydrochloride) dose, indications, adverse effects, interactions... from PDR.netOndansetron (ondansetron hydrochloride) dose, indications, adverse effects, interactions... from PDR.net
Coronary artery spasm (coronary vasospasm) appears to be the most common underlying cause. Therefore, monitor for or advise ... coronary vasospasm / Early / Incidence not known. atrial fibrillation / Early / Incidence not known. ventricular tachycardia / ...
https://www.pdr.net/drug-summary/Ondansetron-ondansetron-hydrochloride-3428.2904
Safety and Efficacy in Adult Subjects With Acute Migraines - Full Text View - ClinicalTrials.govSafety and Efficacy in Adult Subjects With Acute Migraines - Full Text View - ClinicalTrials.gov
... coronary artery vasospasm, and cerebral ischemia. Patients with Myocardial Infarction (MI), Acute Coronary Syndrome (ACS), ... Percutaneous Coronary Intervention (PCI), cardiac surgery, stroke or transient ischemic attack (TIA) during the 6 months prior ...
https://clinicaltrials.gov/ct2/show/NCT03237845
Vascular Toxicities of Novel Cancer Therapies - American College of CardiologyVascular Toxicities of Novel Cancer Therapies - American College of Cardiology
Coronary Artery Vasospasm. Coronary artery vasospasm typically presents with angina, troponin elevation, and ischemic ECG ... Coronary Artery Disease, Coronary Vasospasm, CTLA-4 Antigen, Diabetes Mellitus, Dihydrouracil Dehydrogenase (NADP), Doxorubicin ... coronary artery calcium score; CAD, coronary artery disease; CCB, calcium channel blockers; cCTA, coronary CT angiography; CHF ... with underlying coronary artery disease or pre-existing endothelial dysfunction are at higher risk of coronary vasospasm.66 ...
https://www.acc.org/Latest-in-Cardiology/Articles/2022/05/23/13/25/Vascular-Toxicities-of-Novel-Cancer-Therapies
Prescriptions Drogstore Online Overseas • tamsulosinPrescriptions Drogstore Online Overseas • tamsulosin
A dungeon on how to evaluate whether an improved effect beyond 1 year was due to coronary vasospasm, printed small dioestrous ...
https://www.angelfire.com/ar3/ypyeynyiysy/tamsulosin/index.html
test #29 4.19 Flashcards by Nashid Chaudhury | Brainscapetest #29 4.19 Flashcards by Nashid Chaudhury | Brainscape
contraindicated in prinzmetal angina and CAD bc can cause coronary vasospasm 99 ...
https://www.brainscape.com/flashcards/test-29-419-2235288/packs/3729903
2022 - CPT Coding for Transcatheter Infusion Therapy | Medical Coding Resources2022 - CPT Coding for Transcatheter Infusion Therapy | Medical Coding Resources
Procedures such as thrombolysis in coronary and non-coronary vessels and cerebral vasospasm treatment are included. Multiple ...
https://www.zhealthpublishing.com/coding-products/elearning-courses/cpt-coding-for-transcatheter-infusion-therapy-2022
PercutaneousArteriesLeft anteriAcute CoronarySpasmAnginaStenosisIschemiaComplicationsDiseaseVesselsDiagnosisIncidenceClinicalDissectionEndothelial cellsMicrovascular dysfunctionPatients undergoiStentCauses coronaryInterventionsAngiographyOccurSymptomsAcetylcholineEndothelium-dependentTherapiesVentricularPhospholipaseOcclusionChestNitric oxideDysfunctionAtheroscleroticMechanismsCardiovascularUnstableArrhythmias
Percutaneous8
  • Coronary vasospasm can be induced by percutaneous coronary intervention (PCI) secondary to endothelial denudation and nitric oxide loss. (wikidoc.org)
  • DESCRIPTION (provided by applicant): Patients with type 2 diabetes mellitus (T2-DM) have higher prevalence of no-reflow phenomenon - a poorly understood and unpredictable complication of percutaneous coronary intervention (PCI) in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion of the epicardial coronary artery. (elsevier.com)
  • 4 Treatment modalities include nitrates, calcium channel blockers, nicorandil (not available in the United States), and concomitant percutaneous coronary intervention for organic stenoses. (ochsnerjournal.org)
  • Few minutes after admission, patient developed VF leading to cardiac arrest and was successfully resuscitated and shifted to the cardiac catheterization lab for emergency percutaneous coronary interventions (PCI). (scitechnol.com)
  • The goal of the trial was to evaluate a strategy of percutaneous coronary intervention (PCI) plus medical therapy compared with medical therapy alone in patients with low-risk stable coronary artery disease (CAD). (medscape.com)
  • Rates, Predictors and the Impact Cannabis Misuse on In-hospital Outcomes Among Patients Undergoing Percutaneous Coronary Intervention. (calgarycmmc.com)
  • The Rho/Rho-kinase pathway plays an important role in pathophysiology and progression of various cardiovascular diseases such as hypertension, coronary vasospasm, angina pectoris, and restenosis after percutaneous coronary intervention, all of which are related to arteriosclerosis/atherosclerosis changes of the vasculature. (elsevier.com)
  • TAVRcathAID is an educational tool with step-by-step instructions on how to perform diagnostic coronary angiogram and percutaneous coronary intervention after implantation of a transcatheter aortic valve. (cardiologyapps.com)
Arteries11
  • This syndrome became known as Prinzmetal or variant angina, and was believed to be due to vasospasm in coronary arteries without obstructive lesions. (medscape.com)
  • Multivessel coronary spasm involves several coronary arteries . (wikidoc.org)
  • Coronary vasospasm is the sudden narrowing of the coronary arteries-the blood vessels that supply oxygen to your heart. (upmc.com)
  • Your doctor may perform a coronary angiogram to take images of your coronary arteries, which allows them to see if the blood flow to your heart is restricted. (upmc.com)
  • Your doctor most likely will prescribe medications, such as calcium channel blockers, nitroglycerin, and nitrates, to help expand your coronary arteries and reduce your risk for coronary vasospasm. (upmc.com)
  • Preliminary observations related to this application led to my main hypothesis that small coronary arteries of diabetic patients exhibit a paradoxical constriction to sudden increases in flow, an alteration, which contributes to no reflow. (elsevier.com)
  • To investigate (co)localization of eNOS and arginase I as well as to detect spatial distribution and interaction of Pecam-1 laser scanning confocal microscopy and fluorescence resonance energy transfer approaches will be used in isolated, pressurized coronary arteries and coronary endothelial cells in culture. (elsevier.com)
  • Should the results obtained in the course of the project support my hypothesis this will be the first description of Pecam-1-coupled constrictor prostanoid production in human coronary arteries. (elsevier.com)
  • Many physiologic changes occur during pregnancy, but how these changes affect the spasticity of coronary arteries in patients predisposed to vasospasm is unknown. (ochsnerjournal.org)
  • Non-obstructive coronary artery disease occurs when there is an interruption in the blood supply to the heart, but a person does not have a blockage in their arteries. (beermonstersguidetoalcoholicbeverages.com)
  • Spasm of the large- or medium-sized coronary arteries. (bvsalud.org)
Left anteri2
  • 90% stenosis in mid left anterior descending coronary artery (LAD). (scitechnol.com)
  • Characteristic electrocardiographic pattern indicating a critical stenosis high in left anterior descending coronary artery in patients admitted because of impending myocardial infarction. (wikem.org)
Acute Coronary8
  • Patient Information: A premenopausal female with CKD presented with acute coronary syndrome following haemodialysis.She complained of recurrent angina following haemodialysis sessions since few months which resolved with nitroglycerine.ECG revealed lateral wall myocardial infarction. (scitechnol.com)
  • Spontaneous coronary artery dissection and refractory vasospasm causing acute coronary syndrome associated with hypereosinophilia and IgG-related immunodeficiency in young male: challenging diagnosis and management. (escardio.org)
  • The primary outcome of death, plus acute coronary syndrome, plus stroke, plus emergency hospitalization occurred in 22.0% of the PCI groups versus 33% of the medical therapy group (p = 0.04). (medscape.com)
  • PCI significantly reduced the occurrence of acute coronary syndrome defined as acute MI (new Q waves or cardiac enzymes more than twice the upper limit of normal) or emergency hospitalization for unstable angina. (medscape.com)
  • In the COURAGE trial, there was no difference in the endpoint of hospitalization for an acute coronary syndrome. (medscape.com)
  • Limitations of the JSAP trial include the fact that patients with refractory angina who were electively revascularized were excluded from analysis, and the definition of an acute coronary syndrome was nonconventional since troponin-positive patients were not analyzed. (medscape.com)
  • Acute coronary syndrome was defined as acute MI or unstable angina that required emergency hospitalization. (medscape.com)
  • Endocannabinoid 2-arachidonoylglycerol is elevated in the coronary circulation during acute coronary syndrome. (calgarycmmc.com)
Spasm20
  • Yasue H, Omote S, Takizawa A, Nagao M, Miwa K, Tanaka S. Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm. (medscape.com)
  • The mystery of coronary artery spasm. (medscape.com)
  • Yasue H, Touyama M, Kato H, Tanaka S, Akiyama F. Prinzmetal's variant form of angina as a manifestation of alpha-adrenergic receptor-mediated coronary artery spasm: documentation by coronary arteriography. (medscape.com)
  • Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm. (medscape.com)
  • Coronary artery spasm and the polymorphisms of the endothelial nitric oxide synthase gene. (medscape.com)
  • The endothelial nitric oxide synthase gene -786T/C polymorphism is a predictive factor for reattacks of coronary spasm. (medscape.com)
  • Nakano T, Osanai T, Tomita H, Sekimata M, Homma Y, Okumura K. Enhanced activity of variant phospholipase C-delta1 protein (R257H) detected in patients with coronary artery spasm. (medscape.com)
  • Stern S, Bayes de Luna A. Coronary artery spasm: a 2009 update. (medscape.com)
  • Adlam D, Azeem T, Ali T, Gershlick A. Is there a role for provocation testing to diagnose coronary artery spasm? (medscape.com)
  • Frequency of provoked coronary arterial spasm in 1089 consecutive patients undergoing coronary arteriography. (medscape.com)
  • Frequency of provoked coronary spasms in patients undergoing coronary arteriography using a spasm provocation test via intracoronary administration of ergonovine. (medscape.com)
  • Focal coronary spasm is limited to a localized segment of the coronary artery . (wikidoc.org)
  • Multifocal coronary spasm involves several localized segments of the same coronary artery . (wikidoc.org)
  • The differential diagnosis of coronary spasm during PCI includes abrupt closure due to dissection or thrombus formation. (wikidoc.org)
  • Specifically, right coronary artery spasm can lead to sinus arrest or complete heart block , while left anterior descending artery spasm can lead to ventricular tachycardia or fibrillation . (wikidoc.org)
  • The right coronary artery ostium is prone to catheter-induced spasm, giving the appearance of an ostial lesion on angiography. (wikidoc.org)
  • 1 This variant form of angina-a type of vasospastic angina in which spasm of an epicardial coronary artery leads to myocardial ischemia with representative ST segment changes-is relatively uncommon, with a higher prevalence in eastern countries. (ochsnerjournal.org)
  • Among patients with vasospastic angina, the majority will have single-vessel vasospasm, although data from a multicenter registry of the Japanese Coronary Spasm Association suggest that up to 32% of patients can have multivessel territories. (ochsnerjournal.org)
  • 6 A review of 103 patients with acute myocardial infarction in pregnancy found only 2 cases attributed to coronary spasm. (ochsnerjournal.org)
  • Coronary artery spasm : pathophysiology, diagnosis, and treatment / edited by C. Richard Conti. (who.int)
Angina10
  • Ergonovine maleate testing during cardiac catheterization: a 10-year perspective in 3,447 patients without significant coronary artery disease or Prinzmetal's variant angina. (medscape.com)
  • Physicians should suspect coronary vasospasm if ST segment elevation is detected in patients experiencing angina , and if the ECG completely returns to baseline upon resolution of symptoms. (wikidoc.org)
  • Coronary vasospasm leading to variant angina is uncommon, and the condition is rare in pregnant patients. (ochsnerjournal.org)
  • Prinzmetal's angina or coronary artery vasospasm). (fpnotebook.com)
  • A variant form of angina pectoris caused by coronary artery vasospasm, usually occurring spontaneously and frequently associated with ST segment elevation. (fpnotebook.com)
  • Angina means that there is underlying coronary heart disease. (doereport.com)
  • However one or more diagnostic tests may be needed to exclude angina or to establish the severity of the underlying coronary disease. (doereport.com)
  • Acute coronary syndromes (ACS) represent a physiologic continuum spanning unstable angina, non-Q wave myocardial infarction and Q-wave myocardial infarction. (ispub.com)
  • Although coronary vasospasm , progressive severe fixed stenosis and increased myocardial demand may precipitate or contribute to unstable angina, a platelet-mediated thrombus may well be the most dominant underlying mechanism in a majority of patients. (ispub.com)
  • The first strategy used in the Evaluation of IIb/IIIa Platelet Receptor Antagonist 7E3 in Preventing Ischemic Complications (EPIC) study ( 6 ), where a subset of patients enrolled in the study had unstable angina or non-Q wave myocardial infarction , underwent coronary angioplasty within 10-60 minutes of initiation of abciximab therapy and the infusion was continued for 12 hours afterwards. (ispub.com)
Stenosis1
  • Subsequent coronary CT revealed normal coronaries with no stenosis. (biomedcentral.com)
Ischemia1
  • Because CYP 3A4 inhibition elevates the serum levels of DIHYDROERGOTAMINE, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. (nih.gov)
Complications1
  • Explore cases involving dissections, perforations, and atherectomy as well as less common complications such as longitudinal stent deformation, vasospasm, and air embolism. (cardiologyapps.com)
Disease13
  • Atherosclerotic coronary disease is much more common, and its presence confers a worse prognosis, regardless of the cause of symptoms. (medscape.com)
  • Patients who have coronary artery disease in addition to coronary vasospasm have an overall worse prognosis. (wikidoc.org)
  • A coronary angiogram did not indicate coronary artery disease or any signs of vasospasm. (news-medical.net)
  • TCT-420: Diabetes and Multivessel Coronary Disease. (ajconline.org)
  • Plasma levels of TXB 2 were determined in 40 patients at risk for, or with definite coronary artery disease. (priory.com)
  • Subjects were included in the study according to the presence of definite coronary artery disease (CAD) or were at risk for it. (priory.com)
  • Clinicians define a MINOCA as an acute myocardial infarction without obstructive coronary artery disease and no obvious cause. (beermonstersguidetoalcoholicbeverages.com)
  • Some evidence also suggests that people with MINOCA are less likely to have traditional cardiovascular risk factors, such as a history of smoking, diabetes and obesity, and a family history of coronary heart disease. (beermonstersguidetoalcoholicbeverages.com)
  • It is a common symptom of coronary heart disease (CHD), which occurs when vessels that carry blood to the heart become narrowed and blocked due to atherosclerosis . (doereport.com)
  • Marijuana use and coronary artery disease in young adults. (calgarycmmc.com)
  • Acute coronary syndromes (ACS) may complicate the clinical course of patients with Coronavirus Disease 2019 (COVID-19). (bvsalud.org)
  • Treatment began with IV unfractionated hepa- history of diabetes mellitus, arterial hypertension, rin (18 UI/kg/h), hydroxychloroquine (200 mg oral- coronary heart disease, peripheral arterial disease, ly 2×/d), and antimicrobial drugs (ceftriaxone 1g by and atrial fibrillation (treated with apixaban [2.5 mg IV infusion/d). (cdc.gov)
  • On March 25, 2020, an 84-year-old man with a history of diabetes mellitus, arterial hypertension, coronary heart disease, peripheral arterial disease, and atrial fibrillation (treated with apixaban [2.5 mg orally 2×/d]) sought care for respiratory symptoms, including dyspnea and cough. (cdc.gov)
Vessels4
  • I also hypothesize that stimulation of platelet endothelium cell adhesion molecule -1 (Pecam-1, known as primary flow sensor in endothelium) with increases in intraluminal flow elevates endothelial [Ca2+]i, which via inducing phospholipase A2 and arachidonic acid release leads to enhanced production of thromboxane A2 in coronary vessels of T2-DM patients. (elsevier.com)
  • To test these hypotheses, I aim to isolate small coronary vessels from the (discarded) atrial appendages of patients with T2-DM undergoing cardiac surgery. (elsevier.com)
  • Procedures such as thrombolysis in coronary and non-coronary vessels and cerebral vasospasm treatment are included. (zhealthpublishing.com)
  • In type 1 diabetic rodents we found that although endothelium-dependent and -independent vasodilatory responses in individual coronary vessels are preserved, following inhibition of NO and PGI2 production, there is evidence of localised focal and segmental constrictions. (edu.au)
Diagnosis3
  • The definitive diagnosis of coronary vasospasm is made angiographically by demonstration of reduction of luminal diameter in a discrete segment of the vessel, which is proven to be reversible. (wikidoc.org)
  • Your doctor also may give you medications during this procedure to help confirm the diagnosis of coronary vasospasm. (upmc.com)
  • IMSEAR at SEARO: Diagnosis and management of coronary vasospasm. (who.int)
Incidence1
  • Pathogenetic mechanisms, estimated incidence and clinical and coronary arteriographic findings in 138 patients. (medscape.com)
Clinical2
  • Covid-19 related myopericarditis and spontaneous coronary artery dissection: a clinical challenge. (escardio.org)
  • Fasudil is currently the only Rho-kinase inhibitor available for clinical use and it is approved in Japan for the prevention of vasospasm in patients with subarachnoid hemorrhage. (elsevier.com)
Dissection3
  • In view of typical history suggestive of VA and no obvious thrombus or dissection in culprit artery, vasospasm of LAD was suspected as the likely etiology. (scitechnol.com)
  • Management of anterior ST-segment elevation myocardial infarction in a young patient due to spontaneous coronary artery dissection. (escardio.org)
  • Spontaneous coronary artery dissection in a super dominant RCA presenting with posterior STEMI and diagnosed with OCT. (escardio.org)
Endothelial cells1
  • Moreover, dysfunctional endothelial cells may enhance vasospasm and platelet aggregation. (bvsalud.org)
Microvascular dysfunction1
  • In summary, through the validation of novel SR imaging and diffraction techniques our data has confirmed a role for coronary microvascular dysfunction, via the ROCK pathway and cardiac subcellular impairment, via reduced myosin head extension, in the development of DCM. (edu.au)
Patients undergoi1
  • Incorporation of Gp IIb/IIIa receptor inhibitors have earned a prominent place among the strategies used to reduce the risk of ischemic events in patients undergoing coronary interventions. (ispub.com)
Stent1
  • This app was created in response to the rising interest among interventional cardiologists to learn OCT given its ability to help with image analysis, determination of plaque characteristics, visualization of intra-coronary pathology and stent optimization. (cardiologyapps.com)
Causes coronary1
  • in rhesus monkeys have yielded evidence that estrogen plus MPA causes coronary artery ( arcoxia 90 wirkstoff ) vasospasm, but. (wfcresources.com)
Interventions3
  • The second strategy involves medical stabilization with a GpIIb/IIIa receptor inhibitor before coronary interventions. (ispub.com)
  • Patients who were deemed good candidates for coronary interventions were randomized into abciximab therapy for 18-24 hours before angioplasty and one hour afterwards or placebo treatment with coronary angioplasty. (ispub.com)
  • An educational tool, the BifurcAID app helps guide and teach interventional cardiologists the different techniques of coronary bifurcation interventions, in a step by step manner. (cardiologyapps.com)
Angiography1
  • She had a history of anxiety, depression, and angiography-documented coronary vasospasm in multiple coronary territories. (ochsnerjournal.org)
Occur5
  • In many cases, coronary artery vasospasm can occur spontaneously without an identifiable cause. (medscape.com)
  • Catheter-induced coronary vasospasm is most prone to occur at the ostium of the right coronary artery (RCA). (wikidoc.org)
  • Coronary vasospasm episodes can occur at any time and may last up to 30 minutes. (upmc.com)
  • The hormonal and nervous system changes that occur during pregnancy appear to be a trigger for vasospasm, further highlighted by the quick resolution of the patient's symptoms postdelivery. (ochsnerjournal.org)
  • Also, haemodynamic changes occur during haemodialysis, but its acute effect on coronary circulation is not well understood. (scitechnol.com)
Symptoms2
  • Coronary vasospasm can cause symptoms similar to a heart attack, including pain in your cheek, neck, and jaw, and pain that spreads to your left arm. (upmc.com)
  • Premarketing Experience With his first bottle to buy domain viagra atspace org and signs and symptoms is high in teratogenicity or lithium touching the iris small but significant soreness of the events shortly after is usable as that best way to get high off wellbutrin have reflected coronary vasospasm. (grey-panthers.it)
Acetylcholine1
  • Patients with coronary artery vasospasm appear to have a heightened vasoconstrictor response to acetylcholine as well as an enhanced response to the vasodilator effects of nitrates, an observation that is consistent with a deficiency of endogenous NO activity. (medscape.com)
Endothelium-dependent1
  • Time-course of impaired coronary arteriolar endothelium-dependent dilation after multi-walled carbon nanotube inhalation. (cdc.gov)
Therapies2
  • Therapies for vasospasm will usually take effect within seconds to one minute. (wikidoc.org)
  • Such therapies , when added to a medical stabilization regimen for ACS is expected to enhance the safety of coronary intervention or possibly reduce the need for mechanical intervention. (ispub.com)
Ventricular3
  • Coronary artery vasospasm, or smooth muscle constriction of the coronary artery, is an important cause of chest pain syndromes that can lead to myocardial infarction (MI), ventricular arrhythmias, and sudden death. (medscape.com)
  • The patient had a history of coronary vasospasm with ventricular arrhythmia that required placement of the ICD 5 years prior. (ochsnerjournal.org)
  • Despite these measures, the patient continued to have vasospasm and ventricular tachycardia, so cesarean delivery and tubal ligation were performed. (ochsnerjournal.org)
Phospholipase1
  • Alternative (or coexisting) mechanisms of coronary artery vasospasm include enhanced phospholipase C activity. (medscape.com)
Occlusion2
  • Coronary arterial tone varies normally via physiologic mechanisms, but the degree of vasoconstriction can range along a spectrum extending from undetectable constriction to complete arterial occlusion. (medscape.com)
  • It is commonly caused by an acute occlusion (the blockage of a blood vessel or hollow organ) of a coronary blood vessel secondary to acute plaque rupture (an area of fibrous cap disruption) and thrombosis. (differencebetween.net)
Chest2
  • Coronary artery vasospasm is an important cause of chest pain but not the exclusive cause. (medscape.com)
  • A potential severe side effect of 5-FU is cardiotoxicity, which often presents with chest pain related to coronary vasospasm. (biomedcentral.com)
Nitric oxide1
  • Our data further support a role for ROCK in early diabetic coronary dysfunction, as following nitric oxide synthase/cyclooxygenase blockade, ROCK inhibition greatly reduced regional segmental constrictions and completely alleviated persistent focal stenoses in diabetic animals. (edu.au)
Dysfunction2
  • This demonstrates, for the first time, localised coronary microvascular endothelial dysfunction in early-stage type 1 diabets (T1D). (edu.au)
  • Contributing to this diabetic coronary impairment is the RhoA/Rho-kinase (ROCK) pathway, which had previously been shown to play a role in endothelial dysfunction and coronary vasospasm. (edu.au)
Atherosclerotic1
  • For example, a coronary event caused by rupture of a nonobstructive atherosclerotic plaque with thrombosis, followed by spontaneous reperfusion, may lead to a seemingly normal or innocuous coronary evaluation. (medscape.com)
Mechanisms1
  • The pathophysiologic mechanisms leading to coronary artery vasospasm are not yet completely understood. (medscape.com)
Cardiovascular1
  • Evidence from in vitro and in vivo studies suggests that Rho-kinase inhibitors have beneficial effects on cardiovascular diseases, particularly arteriosclerosis and coronary vasospasm. (elsevier.com)
Unstable1
  • Vasospasm causing unstable arrhythmia from multiple foci can be difficult to treat. (ochsnerjournal.org)
Arrhythmias1
  • Coronary vasospasm can lead to life-threatening arrhythmias , depending on the vessel that is involved. (wikidoc.org)