Coronary Occlusion
Coronary Angiography
Coronary Artery Disease
Coronary Disease
Angioplasty, Balloon, Coronary
Collateral Circulation
Dogs
Myocardial Infarction
Myocardial Reperfusion
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Myocardial Reperfusion Injury
Ischemic Preconditioning, Myocardial
Exposure of myocardial tissue to brief, repeated periods of vascular occlusion in order to render the myocardium resistant to the deleterious effects of ISCHEMIA or REPERFUSION. The period of pre-exposure and the number of times the tissue is exposed to ischemia and reperfusion vary, the average being 3 to 5 minutes.
Coronary Artery Bypass
Myocardium
Hemodynamics
Coronary Thrombosis
Myocardial Stunning
Arterial Occlusive Diseases
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Stents
Coronary Aneurysm
Coronary Restenosis
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Treatment Outcome
Hyperemia
Disease Models, Animal
Adenosine
Ventricular Function, Left
Retinal Vein Occlusion
Blood Flow Velocity
Retinal Artery Occlusion
Arrhythmias, Cardiac
Prospective Studies
Follow-Up Studies
Tantalum
Ventricular Fibrillation
A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
Risk Factors
Heart Ventricles
Percutaneous Coronary Intervention
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Microspheres
Cardiac Catheterization
Echocardiography
Vascular Resistance
Creatine Kinase
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Ultrasonography, Interventional
Myocardial Revascularization
Rabbits
Organotechnetium Compounds
Coronary Care Units
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Cardiotonic Agents
Vasodilation
Dental Occlusion
The relationship of all the components of the masticatory system in normal function. It has special reference to the position and contact of the maxillary and mandibular teeth for the highest efficiency during the excursive movements of the jaw that are essential for mastication. (From Jablonski, Dictionary of Dentistry, 1992, p556, p472)
Swine, Miniature
Necrosis
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Nitroglycerin
Dipyridamole
Ventriculography, First-Pass
Radionuclide ventriculography where a bolus of radionuclide is injected and data are recorded from one pass through the heart ventricle. Left and right ventricular function can be analyzed independently during this technique. First-pass ventriculography is preferred over GATED BLOOD-POOL IMAGING for assessing right ventricular function.
Tomography, X-Ray Computed
Stroke Volume
Severity of Illness Index
Technetium Tc 99m Sestamibi
Radioisotopes
Ischemic Preconditioning
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Tomography, Emission-Computed, Single-Photon
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Brain Ischemia
Endothelium, Vascular
Analysis of Variance
Thrombolytic Therapy
Nicorandil
Random Allocation
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Rats, Sprague-Dawley
Angina Pectoris
Coronary Artery Bypass, Off-Pump
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Ventricular Remodeling
Rats, Wistar
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Vagus Nerve
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Platelet Aggregation Inhibitors
Thallium Radioisotopes
Physical Conditioning, Animal
Pericardium
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Nitric Oxide
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Catheterization
Cardiac Output
Models, Cardiovascular
Sensitivity and Specificity
Constriction, Pathologic
Dobutamine
Reperfusion Injury
Prognosis
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Echocardiography, Doppler
Carotid Artery, Internal
Gamma Cameras
Isoflurane
Tachycardia
Mesenteric Vascular Occlusion
Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)
Risk Assessment
Bloodless Medical and Surgical Procedures
Streptokinase
Ventricular Pressure
The pressure within a CARDIAC VENTRICLE. Ventricular pressure waveforms can be measured in the beating heart by catheterization or estimated using imaging techniques (e.g., DOPPLER ECHOCARDIOGRAPHY). The information is useful in evaluating the function of the MYOCARDIUM; CARDIAC VALVES; and PERICARDIUM, particularly with simultaneous measurement of other (e.g., aortic or atrial) pressures.
Acetylcholine
Peroxidase
Models, Animal
Anesthesia
Therapeutic Occlusion
Cerebral Infarction
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Nitric Oxide Synthase
Anti-Arrhythmia Agents
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Embolization, Therapeutic
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Cerebral Angiography
Guanidines
Heart Conduction System
Magnetic Resonance Angiography
Sirolimus
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Enzyme Inhibitors
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Thiourea
A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.
Postoperative Complications
Carotid Artery Diseases
Observer Variation
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Dose-Response Relationship, Drug
Exercise Test
Ventricular Premature Complexes
A type of cardiac arrhythmia with premature contractions of the HEART VENTRICLES. It is characterized by the premature QRS complex on ECG that is of abnormal shape and great duration (generally >129 msec). It is the most common form of all cardiac arrhythmias. Premature ventricular complexes have no clinical significance except in concurrence with heart diseases.
Cerebral Arterial Diseases
Ischemic Attack, Transient
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
Potassium Channels
ROC Curve
Angioplasty, Balloon
Cardiac Pacing, Artificial
Platelet Aggregation
Cardiovascular Agents
Feasibility Studies
Oxygen Consumption
Tachycardia, Ventricular
An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
Radiopharmaceuticals
NG-Nitroarginine Methyl Ester
Receptors, Purinergic P1
Potassium Channel Blockers
Ischemia
Vasoconstriction
Thrombectomy
Ticlopidine
Magnetic Resonance Imaging
Adenosine Triphosphate
Mucocutaneous Lymph Node Syndrome
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.
Myocytes, Cardiac
Chi-Square Distribution
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Reperfusion
Restoration of blood supply to tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. It is primarily a procedure for treating infarction or other ischemia, by enabling viable ischemic tissue to recover, thus limiting further necrosis. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing REPERFUSION INJURY.
Reciprocal changes in 12-lead electrocardiography can predict left main coronary artery lesion in patients with acute myocardial infarction. (1/321)
Acute left main coronary artery (LMCA) occlusion may result in acute myocardial infarction (AMI) or sudden death. ST elevation in the aVR and V1 leads is reported to be valuable in recognizing LMCA occlusion. Early recognition of electrocardiogram (ECG) changes, such as reciprocal ST depression in other leads, is helpful in averting this disaster. This study aimed to determine the reciprocal ST segment depression of 12-lead ECGs associated with acute LMCA occlusion. From January 2000 to December 2004, 61 patients who underwent emergency percutaneous coronary intervention in 3 hospitals due to AMI associated with LMCA (n = 18) and a left anterior descending coronary artery (LADCA) (n = 43) proximal lesion were selected. Reciprocal ST segment depression occurred in leads aVF, V(2), V(3), V(4), V(5), and V(6) with significantly higher incidence in the LMCA group than in the LADCA group. Stepwise linear multivariate discriminant analysis indicated that ST segment depression in leads aVF, V(2), and V(4) could distinguish the LMCA group from the LADCA group. We concluded that reciprocal ST segment depression in leads V(2), V(4), and aVF of a 12-lead ECG is an important predictor of acute LMCA occlusion. (+info)Embolised stent into the circumflex coronary artery during percutaneous coronary intervention. (2/321)
Dislodgement and embolisation of the new generation of coronary stents before deployment are rare. If it is impossible to withdraw the embolised stent from the coronary artery, the stent may be crushed into the side wall of the coronary artery with a balloon over a wire passed alongside the embolised stent. (+info)Microcirculatory dysfunction in ST-elevation myocardial infarction: cause, consequence, or both? (3/321)
AIMS: Despite advancements over the past years, normal reperfusion at the myocardial level is not achieved in approximately every other patient with ST-elevation myocardial infarction. In the current work, we aimed at reviewing the role of the coronary microcirculation in the development and outcome of this acute coronary syndrome entity. METHODS AND RESULTS: A PubMed/Medline search was performed with the key words acute coronary syndrome, acute myocardial infarction, coronary artery disease, endothelial dysfunction, microcirculation, and reperfusion. The synthesis of the information points to myocardial microcirculatory dysfunction as a consequence of a primary epicardial event, based on the vulnerable plaque concept. As an alternative theory, microcirculatory dysfunction may contribute to the clinical course of the acute coronary event, based on the vulnerable patient concept. The pros and cons of these two viewpoints are to be discussed and their influence on patient management is to be considered. CONCLUSION: Microcirculatory dysfunction in ST-elevation myocardial infarction can be cause, consequence or both according to non-traditional and traditional concepts. (+info)Troponin-I concentration 72 h after myocardial infarction correlates with infarct size and presence of microvascular obstruction. (4/321)
OBJECTIVES: The aim of this study was to use late gadolinium hyper-enhancement cardiac magnetic resonance (LGE-CMR) imaging to determine if a 72-h troponin-I measurement would provide a more accurate estimation of infarct size and microvascular obstruction (MVO) than serial creatine kinase (CK) or early troponin-I values. METHODS: LGE-CMR was performed 3.7+/-1.4 days after medical treatment for acute ST elevation or non-ST elevation myocardial infarction. Infarct size and MVO were measured and correlated with serum troponin-I concentrations, which were sampled 12 h and 72 h after admission, in addition to serial CK levels. RESULTS: Ninety-three patients, of whom 71 had received thrombolysis for ST elevation myocardial infarction, completed the CMR study. Peak CK, 12-h troponin-I, and 72-h troponin-I were related to infarct size by LGE-CMR (r = 0.75, p<0.0001; r = 0.56, p = 0.0003; r = 0.62, p<0.0001 respectively). Serum biomarkers demonstrated higher values in the group with MVO compared with those without MVO (Peak CK 3085+/-1531 vs 1471+/-1135, p<0.001; 12-h troponin-I 58.3+/-46.9 vs 33.4+/-40.0, p = 0.13; 72-h troponin-I 11.5+/-9.9 vs 5.5+/-4.6, p<0.005). The correlation between the extent of MVO and 12-h troponin-I was not significant (r = 0.16), in contrast to the other serum biomarkers (peak CK r = 0.44, p<0.0001; 72-h troponin-I r = 0.46, p = 0.0002). CONCLUSION: A single measurement of 72-h troponin-I is similar to serial CK measurements in the estimation of both myocardial infarct size and extent of MVO, and is superior to 12-h troponin-I measurements. (+info)Type A aortic dissection with partial ostial occlusion of left main coronary artery. (5/321)
A 48-year-old hypertensive male presented with acute retrosternal pain and aortic regurgitation. The electrocardiogram showed ST-segment depression with T-wave inversion in anterolateral leads. Transesophageal echocardiography in long axis view of aorta revealed a spiral intimal flap in ascending aorta extending to the arch, diagnostic of Type A aortic dissection. The short axis view of the aorta showed partial obstruction of the left main coronary artery (LMCA) by the intimal flap with turbulent flow at its ostium. An emergency repair of aortic dissection with reconstruction of aortic wall was done. Postoperative period and ECG were normal. At 12-months of follow up, patient was doing well. (+info)Detection and characterization of coronary bifurcation lesions with 64-slice computed tomography coronary angiography. (6/321)
AIMS: To compare the performance of 64-slice computed tomography coronary angiography (CTCA) and invasive coronary angiography (ICA) in the detection and classification (according to the Medina system) of bifurcation lesions (BLs). METHODS AND RESULTS: We studied 323 consecutive patients undergoing 64-slice CTCA prior to ICA. All coronary segments >or=2 mm in diameter were evaluated for the presence of a significant (>or=50% diameter reduction on quantitative coronary angiography) BL. Evaluation of BL by CTCA included the assessment of significant lumen obstruction in both main and side branch vessels. Forty-one out of 43 patients (46/48 lesions) with significant BL were identified by CTCA. Excluding coronary segments with non-diagnostic image quality (5%), the sensitivity, specificity, and positive and negative predictive values of CTCA for detecting significant BL were 96, 99, and 85 and 99%, respectively. In 39 of these 41 patients, CTCA assessment was concordant with the Medina lesion classification on ICA. CONCLUSION: Sixty-four-slice CTCA allows accurate assessment of complex BL. (+info)Mechanistic investigation into the arrhythmogenic role of transmural heterogeneities in regional ischaemia phase 1A. (7/321)
AIMS: Studies of arrhythmogenesis during ischemia have focused primarily on reentrant mechanisms manifested on the epicardial surface. The goal of this study was to use a physiologically-accurate model of acute regional ischemia phase 1A to determine the contribution of ischaemia-induced transmural electrophysiological heterogeneities to arrhythmogenesis following left anterior descending artery occlusion. METHODS AND RESULTS: A slice through a geometrical model of the rabbit ventricles was extracted and a model of regional ischaemia developed. The model included a central ischaemic zone incorporating transmural gradients of I(K(ATP)) activation and [K+]o, surrounded by ischaemic border zones (BZs), with the degree of ischaemic effects varied to represent progression of ischaemia 2-10 min post-occlusion. Premature stimulation was applied over a range of coupling intervals to induce re-entry. The presence of ischaemic BZs and a transmural gradient in I(K(ATP)) activation provided the substrate for re-entrant arrhythmias. Increased dispersion of refractoriness and conduction velocity in the BZs with time post-occlusion led to a progressive increase in arrhythmogenesis. In the absence of a transmural gradient of I(K(ATP)) activation, re-entry was rarely sustained. CONCLUSION: Knowledge of the mechanism by which specific electrophysiological heterogeneities underlie arrhythmogenesis during acute ischaemia could be useful in developing preventative treatments for patients at risk of coronary vascular disease. (+info)The mechanistic basis for the disparate effects of angiotensin II on coronary collateral growth. (8/321)
OBJECTIVE: We hypothesize that controversial effects of angiotensin II (Ang II) are attributable to its regulation of reactive oxygen species (ROS) and ROS-dependent signaling. METHODS AND RESULTS: Coronary collateral growth (CCG) was stimulated in normal (WKY) and syndrome X (JCR) rats by transient/repetitive ischemia (RI). Blood flow was measured in the normal (NZ) and the collateral-dependent (CZ) zone. In WKY, RI increased CZ flow (0.84 mL/min/g), but RI+subpressor Ang II increased it more (1.24 mL/min/g). This was associated with transient p38 and sustained Akt activation. A hypertensive dose of Ang II decreased CZ flow (0.69 mL/min/g), which was associated with sustained p38 and transient Akt activation. AT1R blockade by candesartan abrogated CZ flow in WKY (0.58 mL/min/g), reduced myocardial superoxide, and blocked p38 and Akt activation. RI-induced CZ flow in JCR was significantly decreased compared with WKY (0.12 mL/min/g), associated with a large increase in superoxide and lack of p38 and Akt activation. CZ flow in JCR was partially restored by candesartan (0.45 mL/min/g), accompanied by reduction in superoxide and partial restoration of p38 and Akt activation. CONCLUSIONS: Ang II/AT1R blockade, at least in part, regulates CCG via generating optimal ROS amounts and activating redox-sensitive signaling. (+info)
Manual of Coronary Chronic Total Occlusion Interventions - 1st Edition
Retrograde coronary chronic total occlusion revascularization: Procedural and in-hospital outcomes from a multicenter registry...
ClinMed International Library | Guidewire Fracture during Crossing A Chronic Coronary Total Occlusion: A Troublesome Experience...
Mayo-Japan Investigation for Chronic Total Occlusion | definition of Mayo-Japan Investigation for Chronic Total Occlusion by...
Novel ``crowbar effect approach to improve success rate of recanalization of coronary chronic total occlusions - IOS Press
Advances in the management of coronary chronic total occlusions<...
Comparison of Outcomes After Percutaneous Coronary Intervention for Chronic Total Occlusion Using Everolimus- Versus Sirolimus-...
Percutaneous Intervention of CTO Lesion and Non-CTO Lesion in Patients with Coronary Chronic Total Occlusion
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Most recent papers with the keyword chronic total occlusion mri | Read by QxMD
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Risk of cardiac and sudden death with and without revascularisation of a coronary chronic total occlusion | Heart
Gateway into the world of coronary chronic total occlusion
Sirolimus-Eluting Stents for Chronic Total Coronary Occlusions - Full Text View - ClinicalTrials.gov
Successful Retrograde Recanalization of a Very Rare Anomalous Origin
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A new percutaneous porcine coronary model of chronic total occlusion.
Ischemic Cardiomyopathy and Chronic Total Occlusions | JACC: Cardiovascular Interventions
Therapeutic angiogenesis with VEGF164 for facilitation of guidewire crossing in experimental arterial chronic total occlusions.
Most recent papers with the keyword Chronic total occlusions | Read by QxMD
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Johns Hopkins Medicine: Find a Doctor
Successful Recanalization of Chronic Total Occlusions Is Associated With Improved Long-Term Survival - American College of...
Johns Hopkins Medicine: Find a Doctor
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CTO PCI Patients With CKD Have More Acute Kidney Injury but Not Dialysis or TLF Over 2 Years | tctmd.com
Dr. Smiths ECG Blog: Why we need continuous 12-lead ST segment monitoring in Wellens syndrome
06/01/2012 - 07/01/2012
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Medical Quack
Hybrid approach improves success of chronic total occlusion angioplasty | Heart
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CardioAct - Crossing of a CTO lesion while tackling perforation
CiNii Articles - MUROHARA Toyoaki
Frantz Medical Group Subsidiary, VasoStar, Awarded $1 Million Research Grant - Redorbit
Patent US6669652 - Guidewire with tapered distal coil - Google Patents
FDA clears Ra Medicals Dabra arteriosclerosis laser
FDA clears Jetstream Navitus for treatment of peripheral vascular disease - Interventional News
Patent US8062316 - Catheter system and method for boring through blocked vascular passages - Google Patents
Endovascular Intervention in Chronically Occluded Inferior Vena Cava
with Modified Sharp Recanalization Technique | OMICS...
Poly(ester amide) block copolymers - Patent # 7699889 - PatentGenius
Shariq Shamim, MD
Live wire segmentation tool for osteophyte detection in lumbar spine X by Suren Eda Naarayana Kulothungan
Coronary occlusion - Wikipedia
Bioabsorbable Polymer Drug-Eluting Stents - Cardiac Interventions Today
Doctor Details
Interventional Treatment of Total Occlusion of Abdominal Aorta
Impaired Coronary Collateral Growth in the Metabolic Syndrome Is in Part Mediated by Matrix Metalloproteinase 12-Dependent...
Patent WO2016201570A1 - Intravascular imaging catheters and methods of use thereof - Google Patents
CABG Plus Optimal Medical Therapy Yields Best Outcomes in Type 2 Diabetes With CAD
Fine-tuning ambient occlusion and bounced light
Coronary occlusion
A coronary occlusion is the partial or complete obstruction of blood flow in a coronary artery. This condition may cause a ... Tsar Nicholas II may have suffered a coronary occlusion right before he was toppled from his throne during the Russian ... In some patients coronary occlusion causes only mild pain, tightness or vague discomfort which may be ignored; however, the ...
Emanuel Hirsch Bloch
Brownell and J. Edgar Hoover"; of a coronary occlusion; in-his Manhattan apartment. Statement issued by the Julius and Ethel ...
Clyde Hurley
He died of a coronary occlusion in Fort Worth leaving two sons and a former wife. Self-taught, he learned to play the trumpet ... Coronary occlusion "004478201". Standard Certificate of Birth (Microfilm) (Report). Fort Worth, Tarrant, Texas: Texas State ...
Coronary thrombosis
Akcay, Murat (July 2018). "Evaluation of thrombotic left main coronary artery occlusions; old problem, different treatment ... Coronary thrombosis refers to the formation and presence of thrombi in the coronary arteries of the heart. Note that the heart ... The coronary sinus is the venous counterpart to the coronary arteries, where de-oxygenated blood returns from heart tissue. A ... Coronary "microembolization" is being explored as a focal point for coronary thrombus formation and subsequent sudden death due ...
Cedars-Sinai Medical Center
March 5, 1950: Showman Sid Grauman - coronary occlusion. May 29, 1951: Comedienne Fanny Brice - cerebral hemorrhage. December 5 ...
John Crighton Bramwell
Bramwell, C. (12 April 1930). "A British Medical Association Lecture on Coronary Occlusion". Br Med J. 1 (3614): 681-685. doi: ...
Bill Onus
Onus died in 1968 of a coronary occlusion. His business enterprises had created a model for cultural maintenance, and helped to ...
Chick Fewster
He died of coronary occlusion at age 49. Fewster played for the Yankees in the 1921 World Series. He was the first player to ...
Thomas Haynes Upton
He died in 1956 of a coronary occlusion. Lawrence, T. F. C. Upton, Thomas Haynes (1889-1956). Australian Dictionary of ...
John Alden (theatre)
He died in 1962, from a coronary occlusion. Australian Dictionary of Biography, online Lane, Richard (2000). The Golden Age of ...
Coronary vasospasm
... refers to when a coronary artery suddenly undergoes either complete or sub-total temporary occlusion. In ... When coronary vasospasm causes an artery to undergo complete occlusion, an EKG might show evidence of ST-segment elevation in ... Ultimately, when large coronary arteries undergo vasospasm, this can lead to either complete or transient occlusion of blood ... When coronary vasospasm occurs, the occlusion temporarily produces ischemia. A wide array of symptoms or presentations can ...
Russell H. Adams
He died of coronary occlusion in Mt. Lebanon, Pennsylvania. Pennsylvania portal Biography portal District Attorney Pittsburgh ...
Harvey N. Middleton
... (February 1943). "The Electrocardiographic Diagnosis and Treatment in Recent Coronary Occlusion". Journal ... Harvey N. Middleton (July 1947). "Electrocardiographic Diagnosis and Prognosis of Recent Coronary Thrombosis or Occlusion". ... "Electrocardiographic Diagnosis and Prognosis of Recent Coronary Thrombosis or Occlusion", Journal of the Indiana State Medical ... "The Electrocardiographic Diagnosis and Treatment in Recent Coronary Occlusion", Journal of the Indiana State Medical ...
Anthony W. Ivins
Ivins died in Salt Lake City of a coronary occlusion. He was buried at Salt Lake City Cemetery. Grave marker of Anthony W. ...
John Finklea
In 1979, Finklea survived a coronary occlusion and bypass surgery. He had a second coronary occlusion and repeated bypass ...
Harold Hardwick
He died of a coronary occlusion on 22 February 1959. List of Olympic medalists in swimming (men) World record progression 4 × ...
Samuel O. Bennion
He died at Salt Lake City of a coronary occlusion. State of Utah Death Certificate S. Dilworth Young, "The Seventies: A ...
Maria Young Dougall
Dougall died in Salt Lake City of a coronary occlusion. She was the mother of three children. Descendants of Brigham Young " ...
William Stern (psychologist)
Stern died suddenly on March 27, 1938 of coronary occlusion. Stern studied at the University of Berlin under the guidance of ...
John Steinbeck
An autopsy showed nearly complete occlusion of the main coronary arteries. In accordance with his wishes, his body was cremated ...
Nicky Whitta
Whitta died at his home in Darebin from a coronary occlusion. It was reported that he had just driven his wife and two sons ...
Frank Dobson (American football)
He was found dead in bed after suffering a coronary occlusion. List of college football coaches with 100 losses List of college ...
John Hays Hammond
He died of coronary occlusion on June 8, 1936, in Gloucester, Massachusetts. He married Natalie Harris (1859 - 1931), of ...
Cliff Fannin
He died at age 42 in Sandusky, Ohio, of a coronary occlusion. "Cliff Fannin". baseball-reference.com. Retrieved 15 February ...
M. Carey Thomas
Thomas died in Philadelphia on December 2, 1935 of a coronary occlusion. She had returned to the city to address Bryn Mawr ...
Neil O'Sullivan
O'Sullivan died unexpectedly of a coronary occlusion while visiting Sydney in 1968. He was survived by his wife and two sons. ...
Frank Rio
The cause of death was a coronary occlusion, causing a heart attack. Associates in the Chicago Outfit took charge of his ...
Henry Ford
"Widow of Automobile Pioneer, Victim of Coronary Occlusion, Survived Him Three Years". Associated Press. September 29, 1950. " ...
Ostial disease
... , namely coronary ostial stenosis, is the occlusion of coronary ostium. Causing factors include atherosclerosis, ... Angelini, P (2012). "Congenital Coronary Artery Ostial Disease". Tex Heart Inst J. 39 (1): 55-9. PMC 3298900. PMID 22412228. ( ...
Elizabeth Bannan
Bannan died of a coronary occlusion on 26 July 1977 in Ballina. "Centenary Ball For "Fortians"". The Sydney Morning Herald. ...
List of ICD-9 codes 390-459: diseases of the circulatory system
NOS 433 Occlusion and stenosis of precerebral arteries 433.0 Occlusion and stenosis of basilar artery 433.1 Occlusion and ... 414.11 Aneurysm of coronary vessels 414.12 Dissection of coronary artery 414.8 Ischemic heart disease, chronic, other 414.9 ... stenosis of carotid artery 433.2 Occlusion and stenosis of vertebral artery 434 Occlusion of cerebral arteries 434.0 Cerebral ... Angina pectoris 413.0 Angina decubitus 413.1 Prinzmetal angina 414 Other forms of chronic ischemic heart disease 414.0 Coronary ...
Robot research initiative
... chronic total occlusion) and thrombus. The lab achieved the world's first microrobot navigation through artery in a live pig. ... Microrobot moving controlled through blood vessel for drug delivery and treatment of coronary artery disease such as CTO( ...
CKLF-like MARVEL transmembrane domain-containing 5
... of the CMTM5 gene's or its products can be used as makers for patient susceptibilities to coronary artery/stent occlusions; and ... and/or one of its CMTM5 proteins may promote atherosclerosis-based coronary artery disease and the stenosis of coronary artery ... Liu TF, Lin T, Ren LH, Li GP, Peng JJ (December 2020). "[Association between CMTM5 gene and coronary artery disease and the ... Association of CMTM5 gene expression with the risk of in-stent restenosis in patients with coronary artery disease after drug- ...
Percutaneous pulmonary valve implantation
Active infection, central vein occlusion, coronary occlusion, and need for other surgeries such as for arrhythmia are ... If coronary compression (which impairs coronary blood flow) is observed with balloon dilation in the right ventricular outflow ... A balloon dilation test is performed first, to confirm that coronary compression will not occur and the procedure can continue ... Rare complications that may require urgent surgery include valve migration, valve embolization, pulmonary artery occlusion, ...
Gordon Bennett (general)
... due to deteriorating health following a coronary occlusion, he sold his orchard and moved to Dural, New South Wales. He ...
Cardiac catheterization
technique is also used to assess the amount of occlusion (or blockage) in a coronary artery, often described as a percentage of ... Coronary angiography is a diagnostic procedure that allows visualization of the coronary vessels. Fluoroscopy is used to ... A common example of cardiac catheterization is coronary catheterization that involves catheterization of the coronary arteries ... Acute coronary syndromes: ST elevation MI (STEMI), non-ST Elevation MI (NSTEMI), and unstable angina Evaluation of coronary ...
ENDOG
... which results from an occlusion of one of the major coronary arteries, is currently still the leading cause of morbidity and ...
Vulnerable plaque
most of the occlusions are too small to see by angiography). Most ruptures and clotting events are too small to produce ... While a single ruptured plaque can be identified during autopsy as the cause of a coronary event, there is currently no way to ... Some of the CT derived plaque characteristics can help predict for acute coronary syndrome. In addition, because these lesions ... 2013). "Additive value of semi-automated quantification of coronary artery disease using cardiac CT-angiography to predict for ...
Stafford LeRoy Irwin
Irwin died in 1955 of a coronary occlusion in Asheville, North Carolina, and was buried at Arlington National Cemetery. Irwin ...
Management of atrial fibrillation
... results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at ... 2003). "Left Atrial Appendage Occlusion Study (LAAOS): a randomized clinical trial of left atrial appendage occlusion during ... Left atrial appendage occlusion is an experimental alternative to anticoagulants. During cardiac catheterization, a device ( ... routine coronary artery bypass graft surgery for long-term stroke prevention". Am. Heart J. 145 (1): 174-78. doi:10.1067/mhj. ...
Martha Baird Rockefeller
... died from a coronary occlusion at the age of 75 on January 24, 1971, at her home at 740 Park Avenue in ...
Periodontal disease
In addition to initial RSI, it may also be necessary to adjust the occlusion (bite) to prevent excessive force on teeth that ... Humphrey LL, Fu R, Buckley DI, Freeman M, Helfand M (December 2008). "Periodontal disease and coronary heart disease incidence ... "Periodontal disease and coronary heart disease: a reappraisal of the exposure". Circulation. 112 (1): 19-24. doi:10.1161/ ... "Relationship of periodontal disease and tooth loss to prevalence of coronary heart disease". Journal of Periodontology. 75 (6 ...
Ray Dunn
He had battled diabetes since the early 1960s, and finally succumbed to a coronary occlusion on 26 August 1971 at his Metung ...
Coronary CT angiography
... allowing physicians to assess the extent of occlusion in the coronary arteries, usually in order to diagnose coronary artery ... Coronary CT angiography (CTA or CCTA) is the use of computed tomography (CT) angiography to assess the coronary arteries of the ... It may be useful in the diagnosis of suspected coronary heart disease, for follow-up of a coronary artery bypass, for the ... Effective dose using MSCT coronary imaging can average less than the dose in conventional coronary angiography. Zhi-hui Hou; ...
Cholesterol embolism
In coronary catheterization, for instance, the incidence is 1.4%. Furthermore, cholesterol embolism may develop after the ... Flory CM (1945). "Arterial occlusions produced by emboli from eroded aortic atheromatous plaques". Am J Pathol. 21 (3): 549-565 ...
ICD-10 Procedure Coding System
... coronary artery dilation), occlusion (fallopian tube ligation), restriction (cervical cerclage) always involve devices: ... 0L occlusion; 0M reattachment; 0N release; 0P removal; 0Q repair; 0R replacement; 0S reposition; 0T resection; 0U supplement ; ...
QuikClot
... a new strategy to avoid early bleeding and subacute radial artery occlusion after percutaneous coronary intervention". J ... "A new kaolin-based haemostatic bandage compared with manual compression for bleeding control after percutaneous coronary ...
Physical therapy
Wurn BF, Wurn LJ, King CR, Heuer MA, Roscow AS, Hornberger K, Scharf ES (February 2008). "Treating fallopian tube occlusion ... An example of cardiac surgery is coronary bypass surgery. The primary goals of this specialty include increasing endurance and ... Pulmonary disorders, heart attacks, post coronary bypass surgery, chronic obstructive pulmonary disease, and pulmonary fibrosis ...
Myocardial infarction complications
... such as mitral regurgitation in the case of left-sided coronary occlusion that disrupts the blood supply of the papillary ... If diagnostic coronary angiography does not reveal a culprit blockage that is the cause of the cardiogenic shock, the prognosis ... Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock" (PDF). N Engl J Med. 341 (9): 625-34. doi:10.1056 ... which may occur in the domain of another atherosclerotic coronary artery, or in the same zone if there are any live cells left ...
Christopher Burke (Irish revolutionary)
He died from coronary occlusion at the age of 65 in his home on 23 June 1964. His sister, Christina Mary "Tena" Burke was ...
Geoffrey Davey
He died at the presbytery there in 1975, aged 68, of a coronary occlusion and was interred at Mona Vale beside his wife. ...
Wayne Morris
Aged 45, Morris died of a coronary occlusion September 14, 1959, aboard the USS Bon Homme Richard. During his naval service, ... contract players, Deaths from coronary artery disease). ...
L. John Nuttall (educator)
Nuttall served in this position for twelve years until he died in Salt Lake City in 1944 of a coronary occlusion. State of Utah ...
Nitrous oxide
Its use for acute coronary syndrome is of unknown benefit. In Britain and Canada, Entonox and Nitronox are used commonly by ... Nitrous oxide at 75% by volume reduces ischemia-induced neuronal death induced by occlusion of the middle cerebral artery in ... 2010). "Part 10: acute coronary syndromes: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and ... oral surgery and acute coronary syndrome (includes heart attacks). Its use during labour has been shown to be a safe and ...
Valentín Fuster
Demonstrating the role of platelets in coronary artery bypass graft (CABG) occlusion based on imaging studies in dogs, and a ... "The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes". New England Journal of Medicine. 326 (5): 310- ... Fuster, V.; Fayad, Z. A.; Badimon, J. J. (1999). "Acute coronary syndromes: biology". Lancet. 353 Suppl 2: SII5-9. doi:10.1016/ ... 2000s: Following upon experience with CABG and DES for revascularization in patients with diabetes and multivessel coronary ...
Rex Connor
Connor's wife died in April 1977 and he died suddenly in Canberra of a coronary occlusion in August of that year. He was ...
Neovascularization
Ischemic heart disease develops when stenosis and occlusion of coronary arteries develops, leading to reduced perfusion of the ... Lassaletta, Antonio D.; Chu, Louis M.; Sellke, Frank W. (November 2011). "Therapeutic neovascularization for coronary disease: ...
Right coronDescending coronary arteryAngiographyDiseasePressure-controlled intermittent coronary sinus occlusionArteriesCentral Retinal APrimary percutaneous coronary intThrombosisAtherosclerosisChronic total occlusionsAcute coronaryClinical Outcomes After Percutaneous Coronary IntApproach in percutaneous coronary intStenosisRadial artery occlusionPatientsRetinalBypass graft surgeryRevascularizationSinusPeripheral arterial occlusionThrombotic occlusionInterventionPerforationComplex coronaryCalcificationReperfusionTreatment of coronaryVentricularMyocardiumCarotidCABGBlockageLigationCardiac catheterizationBalloonIschemic stroke
Right coron11
- CASE REPORT A 40-year-old man was admitted with unstable angina and diagnosed with CTO of the left anterior descending artery (LAD) and right coronary artery . (bvsalud.org)
- METHODS AND RESULTS: Ten subjects with single-vessel right coronary artery disease undergoing percutaneous coronary intervention with normal ventricular function were studied in the BO group. (anglia.ac.uk)
- CONCLUSIONS: RP and right coronary artery balloon occlusion both cause ischemic right ventricular dysfunction with stunning observed later during the procedure. (anglia.ac.uk)
- We present here a case where a patient who had undergone coronary artery bypass grafting presented with headache and on evaluation found to have complete occlusion of right coronary artery. (thieme-connect.de)
- A 55-year-old man was admitted to our hospital with a history of recent inferior wall myocardial infarction with angioplasty of right coronary artery (RCA) 2 weeks back. (thieme-connect.de)
- Fig. 1 Complete occlusion of right coronary artery post-revascularization. (thieme-connect.de)
- This image showed focal dilatation of the proximal right coronary artery (RCA), just distal to the origin of the artery (Figures 2 and 3) corresponding to the soft-tissue abnormality identified on the non-contrast CT scan. (appliedradiology.com)
- The focal dilatation within the proximal right coronary artery contained a small amount of nonocclusive mural thrombus, as well as a thin rim of calcification (Figure 4). (appliedradiology.com)
- A few smaller areas of focal dilatation were identified within the distal right coronary artery (Figure 3). (appliedradiology.com)
- The right coronary artery is most commonly affected. (appliedradiology.com)
- We report here a case of embolic portion of the right coronary artery 5 mm (Figure 2). (who.int)
Descending coronary artery4
- Thirty minutes and six hours after intravenous administration of the benzenesulfonate compound, (CLS 2210) cardiac lymphatics in the distribution of the left anterior descending coronary artery (LAD) were determined and further delineated by postmortem cardiac lymphangiograms. (arizona.edu)
- The death certificate, completed by the county chief deputy coroner, and the autopsy report, completed by the pathologist, listed "cardiac dysrhythmia due to atherosclerotic coronary artery disease and myocardial bridging of anterior descending coronary artery" as the cause of death. (cdc.gov)
- Male Sprague-Dawley rats were submitted to permanent occlusion of the left descending coronary artery. (lww.com)
- Coronary angiography images showed severe stenosis of the left anterior descending coronary artery, which was dilated by percutaneous transluminal coronary angioplasty. (medscape.com)
Angiography10
- From a central database of two hospitals in Milan (San Raffaele Hospital and GVM-EMO Centro Cuore Columbus) a total of 9,789 consecutive patients referred to us over 10 years (January 1998 to March 2008) for coronary angiography, we identified 1,345 patients (13%) who matched the inclusion and exclusion criteria for CTO. (cardiovascularnews.com)
- Triglycerides, HDL level, triglyceride/HDL ratio and atherogenic plasma index before coronary angiography were assessed for the 451 patients who met the study criteria. (experimentalbiomedicalresearch.com)
- Most notably, they specifically indicated for the first time that patients with left bundle branch block (LBBB) patterns or right ventricular pacemakers who manifest Sgarbossa criteria or modified Sgarbossa criteria, and patients with de Winter sign, should undergo emergent coronary angiography. (medscape.com)
- Coronary angiography done at that time showed discrete lesions with critical left main coronary artery stenosis and significant blockage in obtuse marginal artery. (thieme-connect.de)
- 1 Catheter angiography historically was used in detecting coronary artery aneurysms, but due to invasiveness and morbidity, as well as technological advances in other modalities, it is performed less commonly now. (appliedradiology.com)
- With the evolution of multidetector CT, coronary CT angiography (CTA) is becoming more common. (appliedradiology.com)
- Therefore, he underwent emergent coronary angiography. (scirp.org)
- Following diagnostic coronary angiography, PCI for RCA total occlusion was performed. (scirp.org)
- On relook coronary angiography, we could not find any potential cause of cardiac tamponade including coronary arterial perforation ( Figure 4 ). (scirp.org)
- Coronary angiography examination revealed a functional mi- problem. (who.int)
Disease36
- As the heart's arteries become narrowed over time due to atherosclerosis (the buildup of plaque) and coronary artery disease, they can become completely blocked. (henryford.com)
- It offers an option to those whose quality of life is impacted by their coronary artery disease. (henryford.com)
- A growing number of patients, particularly those with advanced, chronic coronary artery disease, experience symptoms of angina that are refractory to treatment with β-blockers, calcium-channel blockers, and long-acting nitrates, despite revascularization. (nature.com)
- Given the Chief's underlying coronary heart disease, NIOSH investigators concluded that the physical stress of performing physical fitness training may have triggered a cardiac arrhythmia and a possible heart attack resulting in his sudden cardiac death. (cdc.gov)
- Also known as CAD, coronary artery disease is the main cause of heart attacks. (qualityhealth.com)
- Symptoms of coronary artery disease include shortness of breath, chest pain, palpitations, and even fatigue, according to the American Heart Association. (qualityhealth.com)
- Coronary artery disease is preventable in many instances, and you can reduce your risk by eating a healthy diet, maintaining a normal weight, and getting plenty of exercise. (qualityhealth.com)
- The death certificate listed "ASCVD" (atherosclerotic coronary vascular disease) as the immediate cause of death, with hyperlipidemia and smoking as contributing factors. (cdc.gov)
- Atypical presentation of coronary artery disease (CAD) is not uncommon and is seen in females and diabetics. (thieme-connect.de)
- Coronary artery aneurysms are a rare complication of a variety of disease processes. (appliedradiology.com)
- Kawasaki disease is the most common cause of coronary artery aneurysms worldwide, particularly in children. (appliedradiology.com)
- Interestingly, clinical disease activity and serological markers do not seem to correlate well with coronary artery vasculitis or aneurysm. (appliedradiology.com)
- Systemic lupus erythematosus is an uncommon cause of coronary artery aneurysms, with Kawasaki disease being a much more common cause in children. (appliedradiology.com)
- However, children with known SLE who present with chest pain should be evaluated for coronary artery disease, including aneurysms, with echocardiograms or contrast enhanced CT. (appliedradiology.com)
- Karrar A, Sequeira W, Block J. Coronary artery disease in systemic lupus erythematosus: A review of the literature. (appliedradiology.com)
- Scientists identified a transcription factor that can change the epigenetic signaling for atherosclerotic plaque formation, potentially heralding a new line of therapy for coronary artery disease. (medpagetoday.com)
- giving hope to those with coronary artery disease. (bumrungrad.com)
- Bumrungrad International Hospital would like to share with you some information on coronary artery disease, including both controllable and uncontrollable risk factors for the condition. (bumrungrad.com)
- These agents should not be used in patients with severe coronary artery disease or severe/uncontrolled hypertension. (drugs.com)
- Reduction of platelet adhesiveness in patients with coronary artery disease. (amjmed.com)
- Measures used to prevent other blood vessel (vascular) diseases, such as coronary artery disease , may decrease the risk for retinal artery occlusion. (medlineplus.gov)
- New York City has one of the highest reported death rates from coronary heart disease in the United States. (cdc.gov)
- We conducted a cross-sectional validation study by using a random sample of death certificates that recorded in-hospital deaths in New York City from January through June 2003, stratified by neighborhoods with low, medium, and high coronary heart disease death rates. (cdc.gov)
- We computed a comparability ratio (coronary heart disease deaths recorded on death certificates divided by validated coronary heart disease deaths) to quantify agreement between death certificate determination and clinical judgment. (cdc.gov)
- Coronary heart disease appears to be substantially overreported as a cause of death in New York City among in-hospital deaths. (cdc.gov)
- Coronary heart disease (CHD) is the leading cause of death for adults in the United States, and stroke ranks third (1). (cdc.gov)
- Age-adjusted deaths from coronary heart disease in New York City (NYC) versus the United States overall. (cdc.gov)
- She had no risk factors for coronary artery disease in her medical history but it was learned that she had undergone a mitral valve replacement 2 years before because of rheumatic mitral stenosis and that no international normalized ratio (INR) analysis had been done in the last 6 months. (who.int)
- Coronary artery bypass grafting (CABG) is performed for patients with coronary artery disease (CAD) to improve quality of life and reduce cardiac-related mortality. (medscape.com)
- Impact of age on clinical outcomes of antihypertensive therapy in patients with hypertension and coronary artery disease: A sub-analysis of the Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease. (twmu.ac.jp)
- Optimal Blood Pressure in Patients With Coronary Artery Disease and Chronic Kidney Disease: HIJ-CREATE Substudy. (twmu.ac.jp)
- Relationships between blood pressure lowering therapy and cardiovascular events in hypertensive patients with coronary artery disease and type 2 diabetes mellitus: The HIJ-CREATE sub-study. (twmu.ac.jp)
- I25.119 is a valid billable ICD-10 diagnosis code for Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris . (icd10coded.com)
- His research plan over the next 5 years is to develop hybrid and innovative surgical and percutaneous revascularisation strategies to improve outcomes of patients with multivessel and complex coronary artery disease. (cardiomuhc.ca)
- Coronary Artery Disease (CAD) is the most prevalent single cause of death and loss of Disability Adjusted Life Years (DALYs) around the world. (verifiedmarketresearch.com)
- Prevention of coronary heart disease : practical management of the risk factors / [edited by] Norman M. Kaplan, Jeremiah Stamler. (who.int)
Pressure-controlled intermittent coronary sinus occlusion3
- Pressure-controlled intermittent coronary sinus occlusion (PICSO), known to induce angiogenetic and vasoactive molecules as well as to reduce regional ischemia, may activate endogenous regenerative processes in failing myocardium. (eur.nl)
- Pressure-controlled Intermittent Coronary Sinus Occlusion study (OxAMI-PICSO study). (ox.ac.uk)
- AIMS: The Oxford Acute Myocardial Infarction PICSO (OxAMI-PICSO) study aimed to assess the efficacy of index of microcirculatory resistance (IMR)-guided therapy with pressure-controlled intermittent coronary sinus occlusion (PICSO) in anterior ST-elevation myocardial infarction (STEMI). (ox.ac.uk)
Arteries6
- An autopsy revealed near-total occlusion of two coronary arteries. (cdc.gov)
- Echocardiography is commonly used as a screening exam, with excellent visualization of the proximal coronary arteries. (appliedradiology.com)
- IVUS ) , uses a specially designed ultrasound probe attached to a catheter that is inserted into the coronary arteries. (bumrungrad.com)
- Wiener I, Tilkian AG, Palazzolo M "Coronary artery spasm and myocardial infarction in a patient with normal coronary arteries: temporal relationship to pseudoephedrine ingestion. (drugs.com)
- Retinal artery occlusion is a blockage in one of the small arteries that carry blood to the retina . (medlineplus.gov)
- Complete blockage of blood flow through one of the CORONARY ARTERIES , usually from CORONARY ATHEROSCLEROSIS . (bvsalud.org)
Central Retinal A2
- Central retinal artery occlusion (CRAO) first was described by Van Graefe in 1859 as an embolic event to the central retinal artery in a patient with endocarditis. (medscape.com)
- The risk for stroke is higher in patients with central retinal artery occlusion (CRAO). (medscape.com)
Primary percutaneous coronary int4
- To evaluate in-hospital outcomes and one-year mortality of patients presenting with ULMSO treated with primary percutaneous coronary intervention (PPCI). (fry-it.com)
- METHODS AND RESULTS: Patients with anterior STEMI treated with primary percutaneous coronary intervention (pPCI) were enrolled. (ox.ac.uk)
- The patient was diagnosed with acute myocardial infarction (AMI) and underwent primary percutaneous coronary intervention (PCI). (scirp.org)
- Variations in the eicosapentaenoic acid-arachidonic acid ratio associated with age in acute myocardial infarction patients undergoing primary percutaneous coronary intervention. (twmu.ac.jp)
Thrombosis5
- Complications from coronary artery aneurysms include thrombosis, embolism, AV fistualization or rupture. (appliedradiology.com)
- If stenosis or thrombosis occurs, coronary stenting can be done, though stenosis from vasculitis can be more difficult to stent than stenosis from atherosclerosis. (appliedradiology.com)
- By written claim served on the respondent-employer on the 21st day of November, 1957, the claimant alleged that he suffered a coronary thrombosis on the 11th day of February, 1957, while in the employ of the respondent. (justia.com)
- Other names for heart attack include acute myocardial infarction, coronary thrombosis, and coronary occlusion. (medindia.net)
- In this paper, we report a rare case of myocardial infarction, which occurred as a result of a coronary embolism in a patient with prosthetic mitral valve thrombosis. (who.int)
Atherosclerosis1
- Patients with SLE frequently have coronary artery manifestations, with atherosclerosis being much more common than aneurysms. (appliedradiology.com)
Chronic total occlusions3
- Coronary chronic total occlusions (CTOs) remain a technical challenge and an unresolved clinical dilemma, even after numerous successes and rapid progression in the field of interventional cardiology. (cardiovascularnews.com)
- Meta-Analysis of Clinical Outcomes of Patients Who Underwent Percutaneous Coronary Interventions for Chronic Total Occlusions. (terumo-europe.com)
- Chronic total occlusions - Current techniques and future directions. (terumo-europe.com)
Acute coronary6
- In conclusion, EDS-MI increases diagnostic accuracy and may serve as an automatic decision support in the early management of patients with suspected acute coronary syndrome. (lu.se)
- Retrosternal chest pain is the classical symptom of acute coronary syndrome (ACS). (thieme-connect.de)
- Acute coronary syndrome (ACS) classically presents as retrosternal pain that radiates to the left arm. (thieme-connect.de)
- Acute coronary syndrome patients with refractory no-reflow fared somewhat better being treated with intracoronary epinephrine instead of adenosine in a small randomized trial. (medpagetoday.com)
- The chest pain of the patient was assessed to be typical of acute coronary syndrome. (who.int)
- We did not perform acute coronary syndrome, coronary elevation myocardial infarction, whereas angioplasty because the obstruction embolism should be kept in mind in the rest present with non-ST elevation was in the distal portion of the vessel those with prosthetic valves even in the myocardial infarction [8]. (who.int)
Clinical Outcomes After Percutaneous Coronary Int1
- Long-term clinical outcomes after percutaneous coronary intervention to treat long lesions in hemodialysis patients in the era of second-generation drug-eluting stents. (twmu.ac.jp)
Approach in percutaneous coronary int1
- Comparison of safety and effectiveness between the right and left radial artery approach in percutaneous coronary intervention. (krakow.pl)
Stenosis2
- Hospital records of patients with chronic total occlusion (100% stenosis) in at least one coronary artery were evaluated. (experimentalbiomedicalresearch.com)
- Coronary stenosis and occlusion are important complications. (appliedradiology.com)
Radial artery occlusion1
- A distal approach to transradial access for coronary catheterization halved rates of radial artery occlusion. (medpagetoday.com)
Patients10
- We aimed to optimize the diagnostic accuracy of EDS-MI in patients with verified acute coronary occlusion as well as patients with non-ischaemic ST deviation and compare its performance with STEMI criteria. (lu.se)
- We studied 135 patients with non-ischaemic ST deviation (perimyocarditis, left ventricular hypertrophy, takotsubo cardiomyopathy and early repolarization) and 117 patients with acute coronary. (lu.se)
- Patients with an ACO need immediate reperfusion therapy via cardiac catheterization with percutaneous coronary intervention or fibrinolysis. (medscape.com)
- The Complex Coronary Artery Intervention Center offers consultations for patients in need of CAD surgery who cannot undergo traditional surgery. (bumrungrad.com)
- Patients who will experience little benefit from coronary revascularization are also excluded. (medscape.com)
- Annual operator volume among patients treated using percutaneous coronary interventions with rotational atherectomy and procedural outcomes : analysis based on a large national registry. (krakow.pl)
- Clinical outcomes in patients undergoing complex, high-risk percutaneous coronary intervention and haemodynamic support with intra-aortic balloon versus Impella pump : real-life single-centre preliminary results. (krakow.pl)
- Safety and Efficacy of Low-Dose Prasugrel as Part of Triple Therapy With Aspirin and Oral Anticoagulants in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention - From the TWMU-AF PCI Registry. (twmu.ac.jp)
- This consensus statement notes that not all patients with COVID-19 who have ST elevation with or without an acute coronary occlusion will benefit from any reperfusion strategy or advanced mechanical support. (medscape.com)
- With mechanical thrombectomy changing the management of stroke and becoming the standard of care for patients with large vessel occlusion (LVO), a new challenge has emerged, adequate access for care. (heart.org)
Retinal3
- In 1868, Mauthner suggested that "spasmodic contractions" could lead to retinal artery occlusion. (medscape.com)
- Branch retinal artery occlusion secondary to percutaneous transluminal coronary angioplasty. (bmj.com)
- The retinal artery occlusion may last for only a few seconds or minutes, or it may be permanent. (medlineplus.gov)
Bypass graft surgery1
- Coronary artery bypass graft surgery is also performed, often with resection of aneurysms. (appliedradiology.com)
Revascularization2
- High Success, Low Complications for Chronic Total Occlusion Revascularization in the Cath Lab: The EXPERT CTO Trial. (terumo-europe.com)
- Analysis of the Updated ACC/AHA Coronary Revascularization Guidelines With Implications for Cardiovascular Anesthesiologists and Intensivists. (amedeo.com)
Sinus3
- Conclusions: Here, we show for the first time that PICSO, a trans-coronary sinus catheter intervention, is associated with an increase in morphogens secreted into cardiac veins, normally present during cardiac development, and a significant induction of cell proliferation. (eur.nl)
- HN - 2008 BX - Granulosa Cells, Cumulus MH - Coronary Sinus UI - D054326 MN - A07.231.908.194.500 MS - A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. (bvsalud.org)
- Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures. (bvsalud.org)
Peripheral arterial occlusion1
- Acute peripheral arterial occlusion (blockage in a leg artery). (clevelandclinic.org)
Thrombotic occlusion1
- Thrombotic occlusion of proximal RCA. (scirp.org)
Intervention11
- To test immediate molecular responses, in both patient groups, coronary venous blood samples were taken at baseline and after 20 min, the time required for the intervention. (eur.nl)
- 30 Acute unprotected left mainstem occlusion emergency percutaneous coronary intervention: analysis of the british cardiovascular intervention society database. (fry-it.com)
- Treatment of coronary pseudoaneurysm detected after percutaneous coronary intervention for chronic total occlusion: A case report. (bvsalud.org)
- Coronary pseudoaneurysm (CPA) are associated with iatrogenic coronary artery dissection or perforation, which rarely reported formation early after percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). (bvsalud.org)
- Figure 4: Successful percutaneous coronary intervention for chronic total occlusion is associated with reduced angina frequency. (nature.com)
- Moreover, the lack of a true randomised controlled trial with a medically treated control group raises the question of whether the survival beneï¬ t demonstrated with successful percutaneous coronary intervention (PCI) is, in fact, related to beneï¬ cial effects of opening a chronically occluded vessel versus potential harm conferred to those with CTO-PCI failed. (cardiovascularnews.com)
- Use of "super-glue" to seal a perforation during chronic total occlusion coronary intervention and the potential to "unglue" it. (uams.edu)
- Current status of percutaneous coronary intervention of chronic total occlusion. (terumo-europe.com)
- Outcomes of Renal Transplant Recipients after Percutaneous Coronary Intervention. (twmu.ac.jp)
- He is also a high-volume and world-renown coronary operator, performing over 300 percutaneous coronary intervention (PCI) per year, mostly from the transradial approach and most referred complex anatomies, and responsible of the new MUHC chronic total occlusion (CTO) and Complex Higher-risk but Indicated Procedures (CHIP) program. (cardiomuhc.ca)
- 25%) CDH, prenatal intervention with tracheal occlusion to reverse pulmonary hypoplasia may be contemplated within the context of the ongoing international randomized controlled trial (RCT) (Tracheal Occlusion to Accelerate Lung Growth [TOTAL] Trial), as preliminary evidence seems to suggest an improvement in survival and morbidity particularly in severe CDH. (sts.org)
Perforation1
- However, as in many areas of medicine, we believe that one size does not fit all and in each case we should balance the real clinical improvement after CTO-PCI recanalisation against the risk that such complex procedures can provide (such as coronary perforation and risk of radiation exposure). (cardiovascularnews.com)
Complex coronary2
- FineDuo is a low profile, multifunctional, dual lumen micro-catheter that provides robust support and easy access to complex coronary vasculature 1 . (terumo-europe.com)
- The Swedish Heart and Vascular Institute is seeking an Interventional Cardiologist for its complex coronary interventional program. (asam.org)
Calcification1
- Rotablator , used in cases of coronary artery calcification. (bumrungrad.com)
Reperfusion3
- The goals of this study were to determine relative 99m Tc-RP517 binding to human leukocyte subtypes and the 99m Tc-RP517 uptake pattern in canine myocardium where inflammation was induced by either coronary occlusion and reperfusion or tumor necrosis factor α (TNFα) injection. (elsevier.com)
- 99m Tc-RP517 was injected intravenously in anesthetized, open-chest dogs before coronary occlusion (90 minutes) and reperfusion (120 minutes) (n=9) or before intramyocardial TNFα injection (n=3). (elsevier.com)
- A balloon catheter was placed in the infarct artery at the same location as that used for induction of MI, and during dynamic 3D PET/CT 3 × 10 7 autologous 18 F-FDG progenitor cells were injected through the central lumen using either (a) 3 cycles of balloon occlusion and reperfusion or (b) high-concentration, single-bolus injection without balloon occlusion ( n = 3 for both protocols). (snmjournals.org)
Treatment of coronary2
- endocarditis, atrial and ventricular mu- ing treatment of coronary embolism. (who.int)
- ACITROM can also be used as an adjunct in the treatment of coronary occlusion (block in heart which reduces oxygen and blood supply leading to heart attack) and transient cerebral ischemic attacks (mini stroke, caused by blockage in the blood vessel supplying the brain). (netmeds.com)
Ventricular1
- BACKGROUND: We sought to determine whether right ventricular stunning could be detected after supply (during coronary balloon occlusion [BO]) and supply/demand ischemia (induced by rapid pacing [RP] during transcatheter aortic valve replacement) in humans. (anglia.ac.uk)
Myocardium1
- that is, myocardium within the distribution of left circumflex coronary (LCC) artery. (arizona.edu)
Carotid1
- Consider ophthalmic artery occlusion or carotid artery obstruction if choroidal filling is significantly delayed. (medscape.com)
CABG1
- The patient was planned for coronary artery bypass grafting (CABG). (thieme-connect.de)
Blockage1
- When this blockage lasts for three months or more, it's referred to as a chronic total occlusion (CTO), which may worsen the quality of life. (henryford.com)
Ligation2
- Investigation of mechanisms showed a significant increase in the leptin:adiponectin plasma concentration ratio in rats subjected to coronary ligation, which was abrogated by GR-1. (nih.gov)
- A total of 242 male rats weighing 200-250 g were submitted to a surgical procedure (coronary artery ligation or simulated surgery). (scielo.br)
Cardiac catheterization1
- You need a cardiac catheterization and coronary artery angiogram to know if you have a chronic total occlusion. (henryford.com)
Balloon6
- We also describe the procedures for basic electrophysiological assessment of conduction properties and atrial fibrillation induction, hemodynamic assessment via pressure-volume loops, right heart and left heart catheterization and the development of a myocardial infarction model by balloon occlusion. (nature.com)
- For in vivo experiments, CPC were harvested before induction of infarction (using 90-min coronary balloon occlusion). (snmjournals.org)
- Dynamic scanning demonstrated a sharp rise in myocardial activity during each cycle of balloon-occlusion cell delivery, with a significant fall in activity (around 80%) immediately after balloon deflation. (snmjournals.org)
- At 1 h, myocardial activity was 8.7% ± 1.5% of total injected dose for balloon-occlusion delivery and 17.8% ± 7.9% for high-concentration, single-bolus delivery ( P = 0.08). (snmjournals.org)
- High-concentration, single-bolus therapy may be as effective as balloon-occlusion delivery. (snmjournals.org)
- An endoluminal balloon is inserted into the trachea with sonoendoscopic guidance at 26-28 weeks for severe CDH and 30-32 weeks for moderate CDH with reversal of tracheal occlusion at 34 weeks. (sts.org)
Ischemic stroke1
- Association of total insulin-like growth factor-I, insulin-like growth factor binding protein-1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke. (shefayekhatam.ir)