An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
The veins and arteries of the HEART.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
The circulation of blood through the CORONARY VESSELS of the HEART.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Narrowing or constriction of a coronary artery.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Spasm of the large- or medium-sized coronary arteries.
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Elements of limited time intervals, contributing to particular results or situations.
Pathologic deposition of calcium salts in tissues.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
The hospital unit in which patients with acute cardiac disorders receive intensive care.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Pressure, burning, or numbness in the chest.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
The hollow, muscular organ that maintains the circulation of the blood.
A heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Drugs used to cause dilation of the blood vessels.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Radiography of the heart and great vessels after injection of a contrast medium.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
VASCULAR DISEASES that are associated with DIABETES MELLITUS.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.
Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
The creation and display of functional images showing where the blood is flowing into the MYOCARDIUM by following over time the distribution of tracers injected into the blood stream.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
The return of a sign, symptom, or disease after a remission.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Substances used to lower plasma CHOLESTEROL levels.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES).
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity.
Pathological conditions involving the HEART including its structural and functional abnormalities.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
A characteristic symptom complex.
ANGINA PECTORIS or angina-like chest pain with a normal coronary arteriogram and positive EXERCISE TEST. The cause of the syndrome is unknown. While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). It is different from METABOLIC SYNDROME X, a syndrome characterized by INSULIN RESISTANCE and HYPERINSULINEMIA, that has increased risk for cardiovascular disease.
A method of recording heart motion and internal structures by combining ultrasonic imaging with exercise testing (EXERCISE TEST) or pharmacologic stress.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Research techniques that focus on study designs and data gathering methods in human and animal populations.
Inhaling and exhaling the smoke of burning TOBACCO.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
The transference of a heart from one human or animal to another.
A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.
7-carbon saturated monocarboxylic acids.
A lipoprotein that resembles the LOW-DENSITY LIPOPROTEINS but with an extra protein moiety, APOPROTEIN (A) also known as APOLIPOPROTEIN (A), linked to APOLIPOPROTEIN B-100 on the LDL by one or two disulfide bonds. High plasma level of lipoprotein (a) is associated with increased risk of atherosclerotic cardiovascular disease.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Disease having a short and relatively severe course.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
Contractile activity of the MYOCARDIUM.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
The degree to which BLOOD VESSELS are not blocked or obstructed.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.
Radiography of blood vessels after injection of a contrast medium.
Obstruction of flow in biological or prosthetic vascular grafts.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
The prevention of recurrences or exacerbations of a disease or complications of its therapy.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Formation and development of a thrombus or blood clot in the blood vessel.
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
Lesions formed within the walls of ARTERIES.
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Conditions with excess LIPIDS in the blood.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Azoles of one NITROGEN and two double bonds that have aromatic chemical properties.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
Therapy with two or more separate preparations given for a combined effect.
Unstable isotopes of rubidium that decay or disintegrate emitting radiation. Rb atoms with atomic weights 79-84, and 86-95 are radioactive rubidium isotopes.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.
Individuals whose ancestral origins are in the continent of Europe.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.
One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
A clinical syndrome characterized by the development of CHEST PAIN at rest with concomitant transient ST segment elevation in the ELECTROCARDIOGRAM, but with preserved exercise capacity.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
A pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.
Period of contraction of the HEART, especially of the HEART VENTRICLES.
Tomography using single-photon emitting RADIONUCLIDES to create images that are captured in times corresponding to various points in the cardiac cycle.
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
The dilatation of the aortic wall behind each of the cusps of the aortic valve.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Imaging of a ventricle of the heart after the injection of a radioactive contrast medium. The technique is less invasive than cardiac catheterization and is used to assess ventricular function.
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.
Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.
Triple-looped protein domains linked by disulfide bonds. These common structural domains, so-named for their resemblance to Danish pastries known as kringlers, play a role in binding membranes, proteins, and phospholipids as well as in regulating proteolysis. Kringles are also present in coagulation-related and fibrinolytic proteins and other plasma proteinases.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.
Motion pictures of the passage of contrast medium through blood vessels.
Therapeutic use of hormones to alleviate the effects of hormone deficiency.
Persistent and reproducible chest discomfort usually precipitated by a physical exertion that dissipates upon cessation of such an activity. The symptoms are manifestations of MYOCARDIAL ISCHEMIA.
The main trunk of the systemic arteries.
The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.

Anti-heart autoantibodies in ischaemic heart disease patients. (1/12062)

One hundred and ninety-nine ischaemic heart disease (IHD) patients were studied with regard to the prevalence of anti-heart autoantibodies (AHA). The incidence of AHA in IHD patients was 1%: one out of 102 patients who suffered acute myocardial infarction (AMI), one out of seventy-two patients who suffered from acute coronary insufficiency (ACI), and none out of twenty-five patients with other signs and symptoms of IHD, had AHA in their sera. An additional 2% of patients who suffered from AMI developed detectable antibody levels during a follow-up period of 15 days. In comparison,, 53% of patients (eight out of fifteen) who underwent heart surgery and who had no AHA prior to operation, developed these antibodies in their sera during 1-2 weeks following operation.  (+info)

Comparative total mortality in 25 years in Italian and Greek middle aged rural men. (2/12062)

STUDY OBJECTIVE: Mortality over 25 years has been low in the Italian and very low in the Greek cohorts of the Seven Countries Study; factors responsible for this particularity were studied in detail. PARTICIPANTS AND SETTINGS: 1712 Italian and 1215 Greek men, aged 40-59 years, cohorts of the Seven Countries Study, representing over 95% of the populations in designated rural areas. DESIGN: Entry (1960-61) data included age, systolic blood pressure (SBP), smoking habits, total serum cholesterol, body mass index (BMI), arm circumference, vital capacity (VC), and forced expiratory volume in 3/4 seconds (FEV); the same data were obtained 10 years later. Multivariate Cox analysis was performed with all causes death in 25 years as end point. MAIN RESULTS: Italian men had higher entry levels of SBP, arm circumference, BMI, and VC; Greek men had higher cholesterol levels, smoking habits, and FEV. Mortality of Italian men was higher throughout; at 25 years cumulative mortality was 48.3% and 35.3% respectively. Coronary heart disease and stroke mortality increased fivefold in Italy and 10-fold in Greece between years 10 and 25. The only risk factor with a significantly higher contribution to mortality in Italian men was cholesterol. However, differences in entry SBP (higher in Italy) and FEV (higher in Greece) accounted for, according to the Lee method, 75% of the differential mortality between the two populations. At 10 years increases in SBP, cholesterol, BMI, and decreases in smoking habits, VC, FEV, and arm circumference had occurred (deltas). SBP increased more and FEV and VC decreased more in Italy than in Greece. Deltas, fed stepwise in the original model for the prediction of 10 to 25 years mortality, were significant for SBP, smoking, arm circumference, and VC in Greece, and for SBP and VC in Italy. CONCLUSION: Higher mortality in Italian men is related to stronger positive effects of entry SBP and weaker negative (protective) effects of FEV; in addition 10 year increases in SBP are higher and 10 year decreases in FEV are larger in Italy. Unaccounted factors, however, related to, for example, differences in the diet, may also have contributed to the differential mortality of these two Mediterranean populations.  (+info)

Is hospital care involved in inequalities in coronary heart disease mortality? Results from the French WHO-MONICA Project in men aged 30-64. (3/12062)

OBJECTIVES: The goal of the study was to assess whether possible disparities in coronary heart disease (CHD) management between occupational categories (OC) in men might be observed and contribute to the increasing inequalities in CHD morbidity and mortality reported in France. METHODS: The data from the three registers of the French MONICA Collaborative Centres (MCC-Lille, MCC-Strasbourg, and MCC-Toulouse) were analysed during two period: 1985-87 and 1989-91. Acute myocardial infarctions and coronary deaths concerning men, aged 30-64 years, were included. Non-professionally active and retired men were excluded. Results were adjusted for age and MCC, using a logistic regression analysis. RESULTS: 605 and 695 events were analysed for 1985-87 and 1989-91, respectively. Out of hospital cardiac arrests, with or without cardiac resuscitation, and 28 day case fatality rates were lower among upper executives in both periods. A coronarography before the acute event had been performed more frequently in men of this category and the proportion of events that could be hospitalised was higher among them. In both periods, the management of acute myocardial infarctions in hospital and prescriptions on discharge were similar among occupational categories. CONCLUSIONS: For patients who could be admitted to hospital, the management was found to be similar among OCs, as was the 28 day case fatality rate among the hospitalised patients. In contrast, lower prognosis and higher probability of being hospitalised after the event among some categories suggest that pre-hospital care and the patient's conditions before the event are the primary factors involved.  (+info)

Short stature and cardiovascular disease among men and women from two southeastern New England communities. (4/12062)

BACKGROUND: Short stature has been associated with an increased risk of coronary heart disease (CHD), although the reason for the association remains unclear. Data on the relation between stature and stroke is more limited. We examined the association between stature and CHD as well as between stature and stroke in men and women from two communities in southeastern New England. METHODS: Coronary heart disease and stroke events were abstracted from medical records between January 1980 and December 1991. An epidemiological diagnostic algorithm developed to measure CHD was used in the present analysis. Unadjusted relative risks (RR) and RR adjusted for age, smoking status, obesity, high-density lipoprotein (HDL) cholesterol <0.91 mmol/l, total cholesterol >6.21 mmol/l, hypertension, diabetes, education, and being foreign born were computed by gender-specific height categories separately for men (n = 2826) and women (n = 3741). RESULTS: A graded inverse association between stature and risk of CHD was observed among men which persisted after adjustment for confounders. Men >69.75 inches had an 83% lower risk of CHD compared with men < or = 65 inches. In addition, the tallest men had a 67% decreased risk of stroke compared with the shortest men. No significant relation between stature and CHD or stroke was observed among women. CONCLUSIONS: These data support the hypothesis that stature is inversely related to both risk of CHD and stroke at least among men. Factors which might explain this association remain to be determined.  (+info)

Natural sporting ability and predisposition to cardiovascular disorders. (5/12062)

We tested the hypothesis that people with a natural ability in 'power sports' (a presumed marker for predominance of type 2, glycolytic muscle fibres) might have increased risks of coronary heart disease (CHD) compared to those with a natural ability in 'endurance sports' (as a marker for predominance of type 1, oxidative muscle fibres). We examined subsequent cardiovascular disorders retrospectively in 231 male former soldiers, aged 34-87 years, who had undergone a course in physical training in the Army School of Physical Training, Aldershot, UK, who assessed themselves as having natural ability in either power (n = 107) or endurance (n = 124) sports. The proportion with CHD, defined as angina and/or coronary angioplasty and/or coronary artery bypass graft and/or heart attack was 18.7% in the 'power group' vs. 9.7% in the 'endurance group' (difference: chi 2 = 3.9, p = 0.05). The proportions with CHD and/or risk factors rose to 39.3% in the 'power group' vs. 25.8% in the 'endurance group' (difference: chi 2 = 4.8, p = 0.03). Under logistic regression analysis, compared to the 'endurance group', the 'power group' had 2.2 (95% CI: 1.00-4.63) the risk of developing CHD, and 1.86 (95% confidence interval: 1.06 to 3.25) the risk of developing CHD and/or risk factors. Men with a natural ability in 'power sports' are at increased risk of developing cardiovascular disorders, compared to men with a natural ability in 'endurance sports'. A predominance of type 2, glycolytic muscle fibres, presumably of genetic origin, may predispose to cardiovascular disorders.  (+info)

The PRIME study: classical risk factors do not explain the severalfold differences in risk of coronary heart disease between France and Northern Ireland. Prospective Epidemiological Study of Myocardial Infarction. (6/12062)

We are studying the contribution of risk and genetic factors, and their interaction, to the development of ischaemic heart disease (IHD) and other cardiovascular endpoints. The study is prospective, based in three centres in the south, east and north of France and in Northern Ireland. A total of 10,592 men aged 50-59 years were recruited from 1991 to 1993, and examined for evidence of IHD at baseline. Subjects are followed annually by questionnaire. Clinical information is validated from hospital and GP records. Demographic characteristics were similar in all four centres. Body mass index was highest in Strasbourg (mean 27.4 kg/m2 vs. 26.3 kg/m2 in Toulouse and Belfast), but total cholesterol, triglyceride and fibrinogen were highest in Belfast. In Belfast, 6.1% reported having had a coronary angiogram, compared to 3.0% in Toulouse. Conversely, 13.8% in Toulouse reported taking lipid-lowering drugs vs. 1.6% in Belfast. As predicted, a history of myocardial infarction (MI) was highest in Belfast (6.1%) and lowest in Toulouse (1.2%). Some 7.1% of Belfast men reported a medical diagnosis of angina vs. 1.5% in Toulouse. Subjects showing evidence of pre-existing IHD will be studied prospectively but treated in the analysis as an additional variable. These results provide a measure of reassurance that these cohorts are representative of the communities from which they are drawn and provide a reliable baseline for prospective evaluation and cross-sectional comparisons. The levels of the classical risk factors found in this study, particularly when examined in combination, as multiple logistic functions based on previous British studies, are very similar between centres and cannot explain the large differences in the incidence of IHD which exist. Additional risk factors may help explain, at least in part, the major differences in incidence of IHD between these study centres.  (+info)

Chlamydia pneumoniae and atherosclerosis. (7/12062)

OBJECTIVE: To review the literature for evidence that chronic infection with Chlamydia pneumoniae is associated with atherosclerosis and acute coronary syndromes. DATA SOURCES: MEDLINE and Institute of Science and Information bibliographic databases were searched at the end of September 1998. Indexing terms used were chlamydi*, heart, coronary, and atherosclerosis. Serological and pathological studies published as papers in any language since 1988 or abstracts since 1997 were selected. DATA EXTRACTION: It was assumed that chronic C pneumoniae infection is characterised by the presence of both specific IgG and IgA, and serological studies were examined for associations that fulfilled these criteria. Pathological studies were also reviewed for evidence that the presence of C pneumoniae in diseased vessels is associated with the severity and extent of atherosclerosis. DATA SYNTHESIS: The majority of serological studies have shown an association between C pneumoniae and atherosclerosis. However, the number of cases in studies that have reported a positive association when using strict criteria for chronic infection is similar to the number of cases in studies which found no association. Nevertheless, the organism is widely found in atherosclerotic vessels, although it may not be at all diseased sites and is not confined to the most severe lesions. Rabbit models and preliminary antibiotic trials suggest that the organism might exacerbate atherosclerosis. CONCLUSION: More evidence is required before C pneumoniae can be accepted as playing a role in atherosclerosis. Although use of antibiotics in routine practice is not justified, large scale trials in progress will help to elucidate the role of C pneumoniae.  (+info)

Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. (8/12062)

OBJECTIVE: To study possible associations between coronary heart disease and serological evidence of persistent infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus. DESIGN: Population based, case-control study, nested within a randomised trial. SETTING: Five general practices in Bedfordshire, UK. INDIVIDUALS: 288 patients with incident or prevalent coronary heart disease and 704 age and sex matched controls. RESULTS: High concentrations of serum IgG antibodies to H pylori were present in 54% of cases v 46% of controls, with corresponding results for C pneumoniae seropositivity (33% v 33%), and cytomegalovirus seropositivity (40% v 31%). After adjustments for age, sex, smoking, indicators of socioeconomic status, and standard risk factors, the odds ratios (95% confidence intervals) for coronary heart disease of seropositivity to these agents were: 1.28 (0.93 to 1.75) for H pylori, 0.95 (0.66 to 1.36) for C pneumoniae, and 1.40 (0.96 to 2. 05) for cytomegalovirus. CONCLUSIONS: There is no good evidence of strong associations between coronary heart disease and serological markers of persistent infection with H pylori, C pneumoniae, or cytomegalovirus. To determine the existence of moderate associations between these agents and disease, however, larger scale studies will be needed that can keep residual confounders to a minimum.  (+info)

TY - JOUR. T1 - Explaining the decline in coronary heart disease mortality rates in Japan. T2 - Contributions of changes in risk factors and evidence-based treatments between 1980 and 2012. AU - Ogata, Soshiro. AU - Nishimura, Kunihiro. AU - Guzman-Castillo, Maria. AU - Sumita, Yoko. AU - Nakai, Michikazu. AU - Nakao, Yoko M.. AU - Nishi, Nobuo. AU - Noguchi, Teruo. AU - Sekikawa, Akira. AU - Saito, Yoshihiko. AU - Watanabe, Taeko. AU - Kobayashi, Yasuki. AU - Okamura, Tomonori. AU - Ogawa, Hisao. AU - Yasuda, Satoshi. AU - Miyamoto, Yoshihiro. AU - Capewell, Simon. AU - OFlaherty, Martin. PY - 2019/9/15. Y1 - 2019/9/15. N2 - Background: We aimed to quantify contributions of changes in risks and uptake of evidence-based treatment to coronary heart disease (CHD) mortality trends in Japan between 1980 and 2012. Methods: We conducted a modelling study for the general population of Japan aged 35 to 84 years using the validated IMPACT model incorporating data sources like Vital Statistics. The main ...
TY - JOUR. T1 - Self-Reported Health and Outcomes in Patients With Stable Coronary Heart Disease. AU - Stewart, Ralph. AU - Hagstrom, Emil. AU - Held, Claes. AU - Wang, Tom. AU - Armstrong, Paul. AU - Aylward, Philip. AU - Cannon, Christopher. AU - Koenig, Wolfgang. AU - Lopez-Sendon, Jose. AU - Mohler III, Emile. AU - Hadziosmanovic, Nermin. AU - Krug-Gourley, Susan. AU - Ramos-Corrales, Marco. AU - Siddique, Saulat. AU - Steg, Philippe. AU - White, Harvey. AU - Wallentin, Lars. PY - 2017. Y1 - 2017. N2 - Background--The major determinants and prognostic importance of self-reported health in patients with stable coronary heart disease are uncertain. Methods and Results--The STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) trial randomized 15 828 patients with stable coronary heart disease to treatment with darapladib or placebo. At baseline, 98% of participants completed a questionnaire that included the question, Overall, how do you feel your general ...
TY - JOUR. T1 - Progression of coronary calcium and incident coronary heart disease events. T2 - MESA (Multi-Ethnic Study of Atherosclerosis). AU - Budoff, Matthew J.. AU - Young, Rebekah. AU - Lopez, Victor A.. AU - A. Kronmal, Richard. AU - Nasir, Khurram. AU - Blumenthal, Roger S.. AU - Detrano, Robert C.. AU - Bild, Diane E.. AU - Guerci, Alan D.. AU - Liu, Kiang. AU - Shea, Steven. AU - Szklo, Moyses. AU - Post, Wendy. AU - Lima, Joao. AU - Bertoni, Alain. AU - Wong, Nathan D.. PY - 2013/3/26. Y1 - 2013/3/26. N2 - Objectives: The study examined whether progression of coronary artery calcium (CAC) is a predictor of future coronary heart disease (CHD) events. Background: CAC predicts CHD events and serial measurement of CAC has been proposed to evaluate atherosclerosis progression. Methods: We studied 6,778 persons (52.8% female) aged 45 to 84 years from the MESA (Multi-Ethnic Study of Atherosclerosis) study. A total of 5,682 persons had baseline and follow-up CAC scans approximately 2.5 ± ...
Stressful Life Events and Coronary Heart Disease Patients, 978-613-8-23434-0, Psychological factors play a very important role in the existence and formation of Heart diseases, especially Coronary Heart Disease (CHD). Nowadays, heart diseases especially CHD which its clinical spectrum varies from silence ischemia to stable angina, unstable angina, myocardial infection and sudden heart death is one of the three main causes of death in the industrial countries besides cancer and brain stroke. Fifty million people die annually around the world; 12 million of them die because of cardiovascular diseases.Stress can affect persons health through behavioral and physiologic changes. Stress can also lead to heart diseases through psychological changes. It seems that stress has direct effects on coronary arteries and heart muscles. Nontraditional risk factors, such as psychological traits, have been increasingly recognized as important contributors to the genesis and outcomes of coronary artery disease. Mental
Indices of socio-economic deprivation are often used as a proxy for differences in the health behaviours of populations within small areas, but these indices are a measure of the economic environment rather than the health environment. Sets of synthetic estimates of the ward-level prevalence of low fruit and vegetable consumption, obesity, raised blood pressure, raised cholesterol and smoking were combined to develop an index of unhealthy lifestyle. Multi-level regression models showed that this index described about 50% of the large-scale geographic variation in CHD mortality rates in England, and substantially adds to the ability of an index of deprivation to explain geographic variations in CHD mortality rates.
The Stanford Five-City Project was initiated in 1978 to evaluate the effects of community-wide health education on coronary heart disease risk factors in two control San Luis Obispo and Modesto and two treatment Monterey and Salinas cities. This paper examines sex differences in the prevalence of smoking, hypercholesterolemia, and hypertension...
This multicenter, randomized, double-blind, placebo-controlled, parallel-group study will evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in patients with stable coronary heart disease (CHD), with CHD risk equivalents or at elevated risk for cardiovascular disease. Eligible patients will be randomized to receive either dalcetrapib 600 mg orally daily or placebo orally daily, on a background of contemporary, guidelines-based medical care. Anticipated time on study treatment is 4 years ...
This multicenter, randomized, double-blind, placebo-controlled, parallel-group study will evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in patients with stable coronary heart disease (CHD), with CHD risk equivalents or at elevated risk for cardiovascular disease. Eligible patients will be randomized to receive either dalcetrapib 600 mg orally daily or placebo orally daily, on a background of contemporary, guidelines-based medical care. Anticipated time on study treatment is 4 years ...
Abstract: Xin-Ke-Shu (XKS), a traditional Chinese medicine (TCM) preparation, has been widely used for treatment of coronary heart disease (CHD) in China. However, the active constituents of XKS and their interactions with targets remain unclear. In this study, we assessed two docking programs, LibDock and AutoDock, by calculating the root-mean-square deviation (RMSD) of X-ray structure reproduction and the enrichment factor (EF) in virtual screening; both proved to be practical in our protein-ligand complex systems. Moreover, the combined use of the two programs yielded better EFs for each target. We therefore used a combination of the two programs to investigate the interactions of the 51 chemical constituents identified from XKS with five CHD targets, namely peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A receptor (HMGR), cyclooxygenase-2 (COX2), and thrombin. The docking results suggest that pueroside A, pueroside ...
heartdiseasehotline - informative website on coronary heart disease, congential heart disease, heart disease women, rheumatic heart disease, heart disease prevention, heart disease risk (archive ID #3) - Read it at RSS2.com
heartdiseasehotline - informative website on coronary heart disease, congential heart disease, heart disease women, rheumatic heart disease, heart disease prevention, heart disease risk - Read it at RSS2.com
Coronary heart disease currently affects more than 7 million Americans, making it the most common form of heart disease. Men initially have a greater risk for developing coronary heart disease than women do. Once a woman reaches menopause however, her risk for heart disease eventually equals or surpasses that of a man. Experts believe this may be due in part to a decrease in the production of estrogen, a female sex hormone that appears to offer some protection against heart disease.. Coronary heart disease remains the number one cause of death for both women and men in the US, accounting for more than 500,000 deaths from heart attacks each year. Experts agree that many of these deaths can be prevented by changes in lifestyle, which when implemented, can directly reduce your chances for developing coronary heart disease.. Risk factors for coronary heart disease are circumstances or conditions that increase the likelihood of your developing this disease. Risk factors are generally divided into two ...
Heart disease is the number one killer in the United States (American Heart Association, 2005). The purpose of this study was to demonstrate the results of a twelve-week exercise program on coronary heart disease risk factors in full-time hospital employees. Methods: The participants were given cardiovascular, weight training, and flexibility recommendations to follow during a twelve-week period. The main heart disease risk factors measured before and after the completion of the exercise program were blood pressure, total cholesterol, HDL-cholesterol, and body mass index. The information was put into the Framingham Heart Score to estimate the participants 10-year risk of developing heart disease. Other factors measured to show the benefits of exercise included resting heart rate, weight, body fat percentage, waist and hip ratio, maximal oxygen uptake (VO2), and flexibility. Results: There were no significant results from any measurements taken.
BACKGROUND Adult height has been inversely associated with coronary heart disease risk in several studies. The mechanism for this association is not well understood, however, and this was investigated by examining components of stature, cardiovascular disease risk factors and subsequent coronary heart disease in a prospective study. METHODS All men aged 45-59 years living in the town of Caerphilly, South Wales were approached, and 2512 (89%) responded and underwent a detailed examination, which included measurement of height and sitting height (from which an estimate of leg length was derived). Participants were followed up through repeat examinations and the cumulative incidence of coronary heart disease-both fatal and non-fatal-over a 15 year follow up period is the end point in this report. RESULTS Cross sectional associations between cardiovascular risk factors and components of stature (total height, leg length and trunk length) demonstrated that factors related to the insulin resistance ...
Results:. Study 1: 10-year cardiovascular mortality was significantly and linearly associated with glycemic control (fasting blood glucose and glycated hemoglobin A1 levels) independently of the mode of treatment. A high fasting blood glucose level significantly predicted cardiovascular mortality in multiple logistic regression analysis independently of other risk factors. Study 2: Glycated hemoglobin A1c was the most important single risk factor associated with coronary heart disease death or all coronary heart disease events. In multiple logistic regression analysis, glycated hemoglobin A1c was significantly associated with coronary heart disease death after adjustment for other cardiovascular risk factors. ...
Higher magnesium intake was linked to a statistically significant risk reduction in fatal coronary heart disease and a risk reduction for sudden cardiac death among postmenopausal women, according to an analysis published in the Journal of Women’s Health.“Our understanding of the etiology and risk factors for fatal coronary heart disease and sudden cardiac death, particularly among
TY - JOUR. T1 - Ten-year predicted coronary heart disease risk in HIV-infected men and women. AU - Kaplan, Robert C.. AU - Kingsley, Lawrence A.. AU - Sharrett, A. Richey. AU - Li, Xiuhong. AU - Lazar, Jason. AU - Tien, Phyllis C.. AU - Mack, Wendy J.. AU - Cohen, Mardge H.. AU - Jacobson, Lisa. AU - Gange, Stephen J.. PY - 2007/10/22. Y1 - 2007/10/22. N2 - Background. Highly active antiretroviral therapy (HAART), in addition to traditional vascular risk factors, may affect coronary heart disease (CHD) risk in individuals with human immunodeficiency virus (HIV) infection. Methods. Among HIV-infected (931 men and 1455 women) and HIV-uninfected (1099 men and 576 women) adults, the predicted risk of CHD was estimated on the basis of age, sex, lipid and blood pressure levels, the presence of diabetes, and smoking status. Results. Among HIV-infected men, 2% had moderate predicted risk of CHD (10-year CHD risk, 15%-25%), and 17% had high predicted risk (10-year CHD risk of ≥25% or diabetes). Among ...
Of the 41 438 participants in the cohort, we excluded the following from the analyses: 193 for having coronary heart disease at baseline; 167 for an implausibly high or low dietary consumption, defined as 3 standard deviations either way from the cohort mean (,788 kcal/day or ,5710 kcal/day); and 321 for lacking data on important variables such as date of coronary heart disease event (n=12), smoking (n=22), diabetes mellitus (n=71), hypercholesterolaemia (n=197), and hypertension (n=60). Thus the analyses were carried out on 40 757 participants.. We used Cox regression to obtain hazard ratios for coronary heart disease according to sex specific quarters of fried food consumption. The quarter (first) with lowest consumption was used as reference. In the Cox models, age was the underlying time variable, with entry time defined as the participants age at recruitment and exit time as the age at the coronary heart disease event, death, or 31 December 2004, whichever came first. To reduce violations ...
Results. Both middle-aged and elderly men with T wave amplitudes ≥0.15 mV had a lower risk of myocardial infarction, coronary heart disease death and sudden death than men with T wave amplitudes 0.05 to 0.15 mV. The adjusted relative risk of coronary heart disease death was 0.5 (95% confidence interval [CI] 0.2 to 1.0); in men with T wave amplitude ≤0.05 mV, relative risk was 2.0 (95% CI 1.3 to 3.1). Slight ST segment elevation was also associated with decreased risk: relative risk 0.5 (95% CI 0.3 to 1.0) compared with the isoelectric ST segment level. In men with ST segment depression, relative risk was 2.2 (95% CI 1.4 to 3.4). The associations of T wave amplitude and ST segment level were independent of each other. ...
I dont know what to make of this new study. http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001177 Background...
I dont like Mondays---day of the week of coronary heart disease deaths in Scotland: study of routinely collected data Academic Article ...
In a prospective study of over 17 000 civil servants followed up for 25 years, there was an inverse association between SES and CHD mortality in participants with and without prevalent CHD at baseline.. The inverse social gradient in CHD mortality could be a result of increased incidence (aetiology), case fatality (prognosis) or both among those of lower SES. Case fatality includes both survival of an acute event, such as myocardial infarction, and prognosis in chronic manifestations of CHD, such as angina. We studied the latter-established CHD in a working population- and found a significant effect of SES on CHD mortality among those with prevalent CHD defined by symptomatic status. When prevalent CHD was defined by Q, ST or T abnormality in the absence of symptoms, the SES effect was similar but the confidence intervals spanned unity. Participants with both symptoms and ECG abnormality were at very high risk (relative to those without symptoms or any ECG abnormality) and in this group there ...
TY - JOUR. T1 - Coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC) study. AU - Chambless, Lloyd E.. AU - Folsom, Aaron R.. AU - Sharrett, A. Richey. AU - Sorlie, Paul. AU - Couper, David. AU - Szklo, Moyses. AU - Nieto, F. Javier. PY - 2003/9/1. Y1 - 2003/9/1. N2 - Risk prediction functions for incident coronary heart disease (CHD) were estimated using data from the Atherosclerosis Risk in Communities (ARIC) Study, a prospective study of CHD in 15,792 persons recruited in 1987-1989 from four U.S. communities, with follow-up through 1998. Predictivity of which individuals had incident CHD was assessed by increase in area under ROC curves resulting from adding nontraditional risk factors and markers of subclinical disease to a basic model containing only traditional risk factors. We also assessed the increase in population attributable risk. The additional factors were body mass index; waist-hip ratio; sport activity index; forced expiratory volume; plasma ...
Doug Manuel, MD, MSc, William M. Flanagan, BM, Meltem Tuna, PhD, Anya Okhmatovskaia, PhD, Philippe Finès, PhD; Carol Bennett, MSc. Coronary heart disease risk factors in Canada: a Microsimulation predictive model. Simulated Technology for Applied Research (STAR). Slideshow 3725048 by cicero
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TY - JOUR. T1 - Value of genetic testing in the prevention of coronary heart disease events. AU - Hynninen, Yrjänä. AU - Linna, Miika. AU - Vilkkumaa, Eeva. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Background: The health economic evidence about the value and optimal targeting of genetic testing in the prevention of coronary heart disease (CHD) events has remained limited and ambiguous. The objective of this study is to optimize the population-level use and targeting of genetic testing alongside traditional risk factors in the prevention of CHD events and, thereby, to assess the cost-benefit of genetic testing. Methods and findings: We compare several strategies for using traditional and genetic testing in the prevention of CHD through statin therapy. The targeting of tests to different patient segments within these strategies is optimized by using a decision-analytic model, in which a patients estimated risk of CHD is updated based on test results using Bayesian methods. We adopt the perspective of ...
TY - JOUR. T1 - Consensus on. T2 - Screening and therapy of coronary heart disease in diabetic patients. AU - Rivellese, A. A.. AU - Piatti, P. M.. PY - 2011/10. Y1 - 2011/10. N2 - The screening and best treatment for coronary heart disease in diabetic patients is still a matter of debate. For this reason the main Italian scientific societies dealing with diabetes and cardiovascular diseases have tried to finalize a document providing shared recommendations based on the available evidence on: 1) how and who to screen for coronary heart disease, 2) methodologies for the characterization of existing coronary heart disease 3) evaluation of the optimal treatment of cardiovascular risk factors and 4) appropriate revascularization procedures. For each of these points, the levels of evidence and strength of recommendations used in the Italian Standard of Care were adopted.. AB - The screening and best treatment for coronary heart disease in diabetic patients is still a matter of debate. For this reason ...
TY - JOUR. T1 - Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke. T2 - A pooled analysis of 97 prospective cohorts with 1·8 million participants. AU - The Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects). AU - Lu, Yuan. AU - Hajifathalian, Kaveh. AU - Ezzati, Majid. AU - Woodward, Mark. AU - Rimm, Eric B.. AU - Danaei, Goodarz. AU - Selmer, Randi. AU - Strand, Bjorn H.. AU - Dobson, A.. AU - Hozawa, A.. AU - Nozaki, A.. AU - Okayama, Akira. AU - Rodgers, A.. AU - Tamakoshi, A.. AU - Zhou, B. F.. AU - Zhou, B.. AU - Yao, C. H.. AU - Jiang, C. Q.. AU - Gu, D. F.. AU - Heng, D.. AU - Giles, Graham G.. AU - Shan, G. L.. AU - Whitlock, G.. AU - Arima, H.. AU - Kim, H. C.. AU - Christensen, H.. AU - Horibe, H.. AU - Maegawa, H.. AU - Tanaka, H.. AU - Ueshima, Hirotsugu. AU - Zhang, H. Y.. AU - Kim, I. S.. AU - Suh, I.. AU - Fuh, J. L.. AU - Lee, J.. AU - Woo, Jean. AU - Xie, J. ...
Objectives. We attempted to determine whether elevated levels of the classic coronary heart disease risk factors are associated with increased coronary risk and all-cause mortality among elderly men with and without coronary heart disease at baseline. Methods. The classic coronary risk factor levels and risk of coronary events and total...
Since it is changing into a typical medical malady, it is necessary to concentrate on the risk factors for coronary heart disease. There are a variety of irregular conditions that have an effect on the guts and the vessels supplying the heart with blood. Coronary heart disease is the foremost widespread quite heart problem. Its additionally the foremost common reason for heart attacks.. Injury that occurs to the center when the supply of blood is reduced is known as coronary heart disease. What normally happens is, deposits that are fatty in nature, build up among the liner of blood vessels whose job its to supply blood to the guts muscles. This causes narrowing of the blood vessels and the ensuing issue could be a reduction within the blood provide to the heart muscles. This causes symptoms of pain called angina.. Causes of Coronary Heart Disease. There are risk factors for coronary heart disease that are thought of to be responsible for this disease. The most important and most well-known ...
BackgroundCurrent guidelines do not recommend routine cardiac stress testing in patients with stable coronary heart disease (CHD) unless they report symptoms of
TY - JOUR. T1 - More on coronary heart disease. T2 - The dietary sense and nonsense [3]. AU - Holmqvist, O. H.. AU - Bassler, T. J.. AU - Enig, M. G.. AU - Stone, N. J.. PY - 1994/1/1. Y1 - 1994/1/1. UR - http://www.scopus.com/inward/record.url?scp=1642500224&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=1642500224&partnerID=8YFLogxK. U2 - 10.1056/NEJM199409013310913. DO - 10.1056/NEJM199409013310913. M3 - Letter. C2 - 8047096. AN - SCOPUS:1642500224. VL - 331. SP - 614. EP - 616. JO - New England Journal of Medicine. JF - New England Journal of Medicine. SN - 0028-4793. IS - 9. ER - ...
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Flint, A.J., et al. (2010) Excess Weight and the Risk of Incident Coronary Heart Disease among Men and Women. Obesity (Silver Spring, Md.), 18, 377-383.
The Treating to New Targets (TNT) trial compared atorvastatin 80 mg (aiming at reducing LDL cholesterol | or = 75 mg/dl) and atorvastatin 10 mg (LDL | or = 100 mg/dl as target) in 10,001 patients with stable coronary heart disease followed up for 5 years. A reduction of major cardiovascular events of 22% was observed in the atorvastatin 80 mg group as compared to the atorvastatin 10 mg group (hazard ratio: 0.78; 95 % interval of confidence: 0.69-0.89; p | 0.001). Such clinical efficacy was obtained while a good drug safety profile was maintained. Total mortality was not significantly different between the two groups. However, and remarkably, cardiovascular death was not the first cause of death anymore in this atorvastatin-treated population. The results of TNT in patients with stable coronary heart disease thus confirm the results of PROVE-IT in patients with acute coronary syndrome. These two randomised controlled trials should encourage considering a LDL cholesterol level of 75 mg/dl (rather than
A high body mass index (BMI) is associated with an increased risk of mortality from coronary heart disease (CHD); however, a low BMI may also be associated with an increased mortality risk. There is limited information on the relation of incident CHD risk across a wide range of BMI, particularly in women. We examined the relation between BMI and incident CHD overall and across different risk factors of the disease in the Million Women Study. 1.2 million women (mean age = 56 years) participants without heart disease, stroke, or cancer (except non-melanoma skin cancer) at baseline (1996 to 2001) were followed prospectively for 9 years on average. Adjusted relative risks and 20-year cumulative incidence from age 55 to 74 years were calculated for CHD using Cox regression. After excluding the first 4 years of follow-up, we found that 32,465 women had a first coronary event (hospitalization or death) during follow-up. The adjusted relative risk for incident CHD per 5 kg/m2 increase in BMI was 1.23 (95%
Lifestyle and risk factor results clearly demonstrate a challenging gap between what is recommended in scientific guidelines and what is achieved in daily practice in high risk individuals in primary prevention of CVD.. Primary prevention of heart disease needs a comprehensive, multidisciplinary approach involving the high-risk population, their GPs and other health professionals, a health insurance system dedicated to prevention and all this complemented by a population strategy involving the community at large.. The European Society of Cardiology together with other partner Societies has engaged in a comprehensive programme of prevention of cardiovascular disease (CVD) since 1994. Guidelines on this important topic have been developed and updated at regular intervals over the last 13 years, most recently in 2007. The implementation of these guidelines is facilitated by the Joint European Prevention Committee and the new European Association for Cardiovascular Prevention and Rehabilitation ...
Coronary heart disease (CHD) is the leading cause of death in the United States. Previous research examining physicians ability to estimate cardiovascular risk has shown that physicians generally overestimate the absolute risk of CHD events. This question has, however, only studied risk prediction for a limited number of patient care scenarios. The aim of this study is to measure the ability of physicians to estimate the risk of CHD events in patients with no previous history of coronary heart disease. Twelve primary prevention scenarios with a 5-year risk of CHD events were developed. This questionnaire was surveyed at 3 university teaching hospitals where the participants were a convenience sample of internal medicine residents and fellows or attending physicians in general internal medicine or cardiology. For each scenario, physicians were asked to estimate the baseline 5-year risk of a coronary heart disease event and the revised risk if the patient were to receive lipid-lowering drug therapy.
Coronary heart disease (CHD) is the leading cause of death in the United States. Previous research examining physicians ability to estimate cardiovascular risk has shown that physicians generally overestimate the absolute risk of CHD events. This question has, however, only studied risk prediction for a limited number of patient care scenarios. The aim of this study is to measure the ability of physicians to estimate the risk of CHD events in patients with no previous history of coronary heart disease. Twelve primary prevention scenarios with a 5-year risk of CHD events were developed. This questionnaire was surveyed at 3 university teaching hospitals where the participants were a convenience sample of internal medicine residents and fellows or attending physicians in general internal medicine or cardiology. For each scenario, physicians were asked to estimate the baseline 5-year risk of a coronary heart disease event and the revised risk if the patient were to receive lipid-lowering drug therapy.
DALLAS, TX -The American Heart Association (AHA) and Verily, (formerly Google Life Sciences) announced today that AstraZeneca (AZ) has joined them in a bold new approach to find a cure for coronary heart disease and improve cardiovascular health. With a commitment of $75 million dollars over at least a five year period, the three organizations have initiated the single largest research project funding one leader and team in the fight to cure coronary heart disease. The application period for this new research enterprise officially opens today at 5:00 PM ET at: www.onebraveidea.com. The three organizations have joined forces to find one brave idea from a visionary leader. This person and their team will be awarded the opportunity and challenge to make a difference for the millions of people directly affected by coronary heart disease. Their goal: prevent or reverse coronary heart disease and its consequences, therein restoring cardiovascular health. Launched as One Brave Idea™, this research ...
Objective To assess the effect of using different risk calculation tools on how general practitioners and practice nurses evaluate the risk of coronary heart disease with clinical data routinely available in patients records. Design Subjective estimates of the risk of coronary heart disease and results of four different methods of calculation of risk were compared with each other and a reference standard that had been calculated with the Framingham equation; calculations were based on a sample of patients records, randomly selected from groups at risk of coronary heart disease. Setting General practices in central England. Participants 18 general practitioners and 18 practice nurses. Main outcome measures Agreement of results of risk estimation and risk calculation with reference calculation; agreement of general practitioners with practice nurses; sensitivity and specificity of the different methods of risk calculation to detect patients at high or low risk of coronary heart disease. Results Only a
The Effective Health Care Program of the AHRQ has released summary guides for clinicians and consumers that discuss adjunctive therapy options for patients with stable coronary heart disease.
Treating depression in those with coronary heart disease: CODIACS Vanguard Randomized Controlled Trial. NEW YORK - Depressive symptoms after heart disease are associated with a markedly increased risk of death or another heart attack. However, less has been known about whether treating heart attack survivors for depressive symptoms could relieve these symptoms, be cost-effective, and ultimately, reduce medical risk? Columbia University Medical Centers Karina W. Davidson, PhD and her research team now report a patient-centered approach that answers these questions in the affirmative.. With a grant from the National Institutes of Healths National Heart, Lung, and Blood Institute (NHLBI), Dr. Karina Davidson, director of the Center for Behavioral Cardiovascular Health at CUMC, and her team completed a randomized controlled trial with 150 patients with elevated depressive symptoms two to six months after hospitalization for heart disease. Patients were recruited from seven centers across the ...
TY - JOUR. T1 - Can non-medical factors contribute to disparities in coronary heart disease treatments?. AU - Barnhart, Janice M.. AU - Cohen, Oshra. AU - Wright, Natania. AU - Wylie-Rosett, Judith. PY - 2006/8/1. Y1 - 2006/8/1. N2 - Racial/ethnic and sex disparities in coronary heart disease treatment exist. We previously reported that physicians perceive non-clinical variables, such as a patients desire for a second opinion, as affecting revascularization decisions. The results of that study are further examined here, using factor analysis to identify significant interrelationships among the non-clinical variables, which could contribute to disparities in coronary revascularization (i.e., percutaneous transluminal coronary angioplasty [PTCA] or coronary artery bypass graft [CABG]). Five content themes emerged using factor analysis; these are related to the patients socioeconomic/lifestyle status, treatment preference, physician interaction, health-assertiveness, and aggressiveness. For the ...
Coronary heart disease (CHD) is when your coronary arteries become narrowed by a gradual build-up of fatty material within their walls called atherosclerosis. These arteries supply your heart muscle with oxygen-rich blood. The most common symptom of coronary heart disease (CHD) is chest pain.. You can also experience other symptoms, such as a light headed sensation, palpitations and shortness of breath. Some people may not have any symptoms before they are diagnosed.. Your arteries may become so narrow that they cannot deliver enough oxygen-rich blood to your heart. The pain and discomfort you may feel as a result is called angina.. If a piece of atheroma breaks off it may cause a blood clot to form. If it blocks your coronary artery and cuts off the supply of oxygen-rich blood to your heart muscle, your heart may become permanently damaged. This is known as a heart attack.. There are several ways you can help reduce your risk of developing coronary heart disease (CHD), such as lowering your ...
In the article by Williams et al, Is Optimal Medical Therapy Optimal Therapy for Multivessel Coronary Artery Disease?: Optimal Management of Multivessel Coronary Artery Disease, which appeared in the September 7, 2010 issue of the journal (Circulation 2010;122:943-945), there were two typographical errors:. On page 943, in the fourth paragraph Coronary Artery Surgical Study should read Coronary Artery Surgery Study.. In the same paragraph, European Coronary Surgical Study should read European Coronary Surgery Study.. The text has been corrected in the current online version of the manuscript. The authors regret the error.. ...
Baseline characteristics were compared between people with and without a family history of premature CHD. A Student t test was used for continuous variables (age, body mass index, waist circumference, waist/hip ratio, systolic and diastolic blood pressure, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol) a χ2 test was used for categorical variables (sex, smoking status, diabetes mellitus). Because triglycerides and the FRS were not normally distributed, these parameters were log-transformed. The log-transformed variables were normally distributed and were compared using a Student t test.. The Framingham risk score was calculated using a previously reported algorithm, which takes into account age, sex, total cholesterol, HDL cholesterol, systolic and diastolic blood pressure, smoking and the presence of diabetes. Since the FRS overestimates CHD risk in Europeans, and more specifically in the EPIC-Norfolk study population, we recalibrated ...
In this analysis of the data from a longitudinal study on coronary heart disease risk factors, it was found that participants screened a few weeks after a major disaster (earthquake) had a higher heart rate, serum cholesterol levels, and serum triglyceride levels than matched participants that were screened shortly before the catastrophic event. The two groups of participants did not differ with regard to their characteristics at the baseline examination carried out 5 years previously. The lack of difference in blood pressure between exposed and nonexposed participants could be explained by the lag-time between the earthquake and the blood pressure measurements. We conclude that the acute stress associated with major disasters can influence risk factors for coronary heart disease. Permanent elevation of these risk factors due to the disruption of the social environment of the individuals affected by major disasters might be responsible for the apparent long-term adverse effects on cardiovascular ...
3 Department of Epidemiology, School of Public Health, Loma Linda University, Loma Linda, CA. Whole blood viscosity, plasma viscosity, hematocrit, and fibrinogen are considered independent risk factors for coronary heart disease and can be elevated by dehydration. The associations between fatal coronary heart disease and intake of water and fluids other than water were examined among the 8,280 male and 12,017 female participants aged 38-100 years who were without heart disease, stroke, or diabetes at baseline in 1976 in the Adventist Health Study, a prospective cohort study. A total of 246 fatal coronary heart disease events occurred during the 6-year follow-up. High daily intakes of water (five or more glasses) compared with low (two or fewer glasses) were associated with a relative risk in men of 0.46 (95% confidence interval (CI): 0.28, 0.75; p trend = 0.001) and, in women, of 0.59 (95% CI: 0.36, 0.97). A high versus low intake of fluids other than water was associated with a relative risk of ...
Title: Depression in Coronary Heart Disease Patients: Etiological and Screening Issues. VOLUME: 2 ISSUE: 2. Author(s):Colin R. Martin and David R. Thompson. Affiliation:Faculty of Medicine, TheNethersole School of Nursing, Chinese University of Hong Kong, EstherLee Building, Chung Chi College, Shatin, New Territories, Hong Kong,Peoples Republic of China.. Keywords:selective serotonin re-uptake inhibitor (SSRI), sertraline anti-depressant heart attack randomised, trial (SADHART), cardiac rehabilitation (CR), PHQ-2, CHD risk factor. Abstract: Coronary heart disease (CHD) is associated with significant psychiatric comorbidity, in particular, depression. Recent evidence suggests that depression following a coronary event or diagnosis is a significant risk factor for both mortality and morbidity. Further, there is compelling evidence that depression is a significant predictor in the development of CHD. Surprisingly, given the relationship of depression to patient outcome, screening for depressive ...
Effect of intensive lipid lowering with atorvastatin on cardiovascular outcomes in coronary heart disease patients with mild-to-moderate baseline elevations in alanine aminotransferase ...
TY - JOUR. T1 - Coronary heart disease mortality trends in Minnesota, 1960-80. T2 - The Minnesota heart survey. AU - Gillum, R. F.. AU - Hannan, P. J.. AU - Prineas, R. J.. AU - Jacobs, D. R.. AU - Gomez-Marin, O.. AU - Luepker, R. V.. AU - Baxter, J.. AU - Kottke, T. E.. AU - Blackburn, H.. N1 - Copyright: Copyright 2017 Elsevier B.V., All rights reserved.. PY - 1984. Y1 - 1984. N2 - Age-adjusted mortality rates and trends from coronary heart disease (CHD) in Minnesota for the years 1960 to 1980 differed among eight health service areas. Regression of ten socio-economic and demographic factors and intensive care and coronary care unit beds on area CHD mortality levels revealed a significant positive association only for levels of welfare income-maintenance assistance with CHD mortality levels; there were no associations with trends. Further studies are needed to explain variation within states of CHD mortality rate levels and trends.. AB - Age-adjusted mortality rates and trends from coronary ...
HealthDay News - Incident coronary heart disease (CHD) is associated with accelerated cognitive decline after, but not before, the event, according to a study published in the June 25 issue of the Journal of the American College of Cardiology.. Wuxiang Xie, PhD, from the Peking University Health Science Center in Beijing, and colleagues examined the cognitive trajectory before and after incident CHD diagnosis in a cohort of 7888 participants with no history of stroke or incident stroke during follow-up. Participants underwent a cognitive assessment at baseline in 2002 to 2003 and at least one other time point (from 2004-2005 to 2016-2017). Incident CHD was defined as a diagnosis of myocardial infarction and/or angina during follow-up.. The researchers observed a correlation for incident CHD with accelerated cognitive decline during a median follow-up of 12 years. The annual rate of cognitive decline was similar before CHD diagnosis for individuals who experienced incident CHD and for those who ...
TY - JOUR. T1 - Employment and recreation patterns in patients treated by percutaneous transluminal coronary angioplasty. T2 - A multicenter study. AU - Holmes, David. AU - Vlietstra, Ronald E.. AU - Mock, Michael B.. AU - Smith, Hugh C.. AU - Dorros, Gerald. AU - Cowley, Michael J.. AU - Kent, Kenneth M.. AU - Hammes, La Von N.. AU - Janke, Lynne. AU - Elveback, Lila R.. AU - Vetrovec, George W.. PY - 1983/10/1. Y1 - 1983/10/1. N2 - Employment and recreational patterns were analyzed in 279 patients who underwent percutaneous transluminal coronary angioplasty (PTCA) for treatment of symptomatic coronary artery disease. PTCA was successful in 180 patients (65%). When it was unsuccessful, coronary artery bypass graft surgery was usually performed (80%). Return-to-work rates were high irrespective of the outcome of PTCA. Of patients employed full-time or part-time before treatment, 98.5% of those who had successful PTCA alone and 97% of those whose PTCA was unsuccessful but who underwent ...
From Clinical Nutrition and Risk Factor Modification Center (D.J.A.J., C.W.C.K., A.M., E.V.), Department of Medicine, Division of Endocrinology and Metabolism (P.W.C.), and Department of Surgery, Division of Otolaryngology (W.Q., J.S.H.), St Michaels Hospital, Toronto, Ontario, Canada; Departments of Nutritional Sciences (D.J.A.J., C.W.C.K., A.M., T.L.P., D.F., E.V.), Biochemistry (P.W.C.), and Laboratory Medicine and Pathobiology (P.W.C.), Faculty of Medicine, University of Toronto, Toronto, Ontario; the Almond Board of California (K.G.L.), Modesto, Calif; and Health Research and Studies Center (G.A.S.), Los Altos, Calif. ...
Background The prevalence of coronary heart disease amongst South Asian population in the UK is higher compared to the general population. Objective This study sought to investigate beliefs and experiences of South Asian patients regarding coronary heart disease and medication taking behaviour. Setting A London Heart Attack Centre. Methods This mixed method study is part of an original pilot randomised study on 71 patients involving a pharmacy-led intervention to improve medication adherence in coronary heart disease patients. South Asian patients from the randomised study took part in qualitative semi-structured telephone interviews. Both South Asian and non-South Asian patients completed the questionnaire about adherence and beliefs regarding medicines using Morisky Scale and the Belief About Medicines Questionnaire-Specific at 2 weeks, 3 and 6 months. Outcome Patients beliefs about coronary heart disease and medication adherence. Results Seventeen South Asian patients and 54 non-South Asian ...
TY - JOUR. T1 - The role of public health versus invasive coronary interventions in the decline of coronary heart disease mortality. AU - Myocardial Infarction Data Acquisition System (MIDAS 39) Study Group. AU - Tuppo, Ehab E.. AU - Trivedi, Mihir P.. AU - Kostis, John B.. AU - Daevmer, Julian. AU - Cabrera, Javier. AU - Kostis, William J.. N1 - Funding Information: The authors would like to thank Dr. George Rhoads for his help in the research and data analysis and Dr. John Pantazopoulos for his help in the discussion. Publisher Copyright: © 2020 Elsevier Inc.. PY - 2021/3. Y1 - 2021/3. N2 - Purpose: There has been considerable debate on the extent to which the decline in coronary heart disease (CHD) mortality has been caused by better control of coronary risk factors in the general population or is the result of invasive coronary interventions in symptomatic individuals. Methods: Using the Myocardial Infarction Data Acquisition System, a statewide database of all cardiovascular hospital ...
Despite advances made in treating coronary heart disease (CHD), mortality due to CHD in Syria has been increasing for the past two decades. This study aims to assess CHD mortality trends in Syria between 1996 and 2006 and to investigate the main factors associated with them. The IMPACT model was used to analyze CHD mortality trends in Syria based on numbers of CHD patients, utilization of specific treatments, trends in major cardiovascular risk factors in apparently healthy persons and CHD patients. Data sources for the IMPACT model included official statistics, published and unpublished surveys, data from neighboring countries, expert opinions, and randomized trials and meta-analyses. Between 1996 and 2006, CHD mortality rate in Syria increased by 64%, which translates into 6370 excess CHD deaths in 2006 as compared to the number expected had the 1996 baseline rate held constant. Using the IMPACT model, it was estimated that increases in cardiovascular risk factors could explain approximately 5140 (81%
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This study examines the joint and separate influence of birth weight and body mass in young adulthood on subsequent coronary heart disease (CHD) risk. A cohort of 9,143 men born in Copenhagen, Denmark, in 1953, for whom information on birth weight and body weight and height around age 19 years were retrieved from birth certificates and conscript records, respectively, were followed from 1978 until 2005 (between age 25 and 52 years) for incident fatal and non-fatal CHD. Data on CHD were obtained through record linkage to the Cause of Death Registry and the National Patient Registry. During follow-up, a total of 475 men had a CHD diagnosis. Men with low birth weight, high body mass index (BMI) at age 19, a father from the working class, and low educational level at age 19 had an increased risk for CHD. Birth weight was inversely associated with CHD only in men with BMI of 25 kg/m(2) or above. Adjustment for childhood social circumstances and educational status at age 19 had minor influence on the ...
Motlagh B, ODonnell M, Yusuf S. Prevalence of cardiovascular risk factors in the Middle East: a systematic review. Eur J Cardiovasc Prev Rehabilm2009;16(3):268-80. Cole JH, Sperling LS. Premature coronary artery disease:clinical risk factors and prognosis. Curr Atheroscler Rep2004;6(2):121-5. Roest AM, Zuidersma M, de Jonge P. Myocardial infarction and generalized anxiety disorder: a 10-year follow-up. Br J Psychiatry 2012;200(4):324-9. Martens EJ, de Jonge P, Na B, et al. Scared to death? Generalized anxiety disorder and cardiovascular events in patients with stable coronary heart disease: The Heart and Soul Study. Arch Gen Psychiatry 2010;67(7):750-8. Huffman JC, Smith FA, Blais MA, et al. Anxiety, independent of depressive symptoms, is associated with in-hospital cardiac complications after acute myocardial infarction. J Psychosom Res 2008;65(6):557-63. Kawachi I, Sparrow D, Vokonas PS, et al. Symptoms of anxiety and risk of coronary heart disease. The NormativeAging Study. Circulation ...
TY - JOUR. T1 - Sleep duration, sleep quality and coronary heart disease mortality. AU - Strand, Linn B.. AU - Tsai, Min Kuang. AU - Gunnell, David. AU - Janszky, Imre. AU - Wen, Chi Pang. AU - Chang, Shu-Sen. PY - 2016/11/15. Y1 - 2016/11/15. KW - Sleep. KW - coronary heart disease. KW - cardiovascular disease. KW - sleep duration. KW - sleep quality. U2 - 10.1016/j.ijcard.2016.08.119. DO - 10.1016/j.ijcard.2016.08.119. M3 - Letter (Academic Journal). C2 - 27552574. VL - 223. SP - 534. EP - 535. JO - International Journal of Cardiology. JF - International Journal of Cardiology. SN - 0167-5273. ER - ...
The most abundant steroid in the human body, dehydroepiandrosterone (DHEA) is involved in the manufacture of testosterone, estrogen, progesterone, and corticosterone. Claes Ohlsson, from Sahlgrenska Academy (Sweden), and colleagues monitored 2,614 men, ages 69 to 80 years, who resided in 3 Swedish communities, for five years, during which DHEA levels were assessed. The findings demonstrated that the lower the DHEA level at the study start, the greater the risk of coronary heart disease events during the five-year follow-up. The study authors report that: Low serum levels of DHEA and its sulfate predict an increased risk of [coronary heart disease], but not [cerebrovascular disease], events in elderly men.. Asa Tivesten; Liesbeth Vandenput; Daniel Carlzon; Maria Nilsson; Magnus K. Karlsson; Claes Ohlsson; et al. Dehydroepiandrosterone and its Sulfate Predict the 5-Year Risk of Coronary Heart Disease Events in Elderly Men. J Am Coll Cardiol. 2014; 64(17):1801-1810.. ...
A comprehensive study in this weeks PLoS Medicine shows levels of the amino acid, homocysteine, have no meaningful effect on the risk of developing coronary heart disease, closing the door on the previously suggested benefits of lowering homocysteine with folate acid once and for all.. Previous studies have suggested that high blood levels of homocysteine might be a modifiable risk factor for coronary heart disease, but in a detailed analysis of data from 19 unpublished and 86 published studies, led by Robert Clarke from the Clinical Trial Service Unit and Epidemiological Studies Unit at the University of Oxford, the researchers found that lifelong moderate elevation of homocysteine levels had no significant effect on the risk of developing coronary heart disease. The study findings suggest that extensive publication bias, together with methodological problems, has played a role in previous suggestions linking homocysteine with coronary heart disease risk.. In their analysis, the authors found ...
TY - JOUR. T1 - A comparison of coronary heart disease event rates amoung urban Australian Aboriginal people and a matched non-Aboriginal population. AU - Bradshaw, Pamela. AU - Alfonso-Parada, Helman. AU - Finn, Judith. AU - Owen, Julie. AU - Thompson, Peter. PY - 2011. Y1 - 2011. U2 - 10.1136/jech.2009.098343. DO - 10.1136/jech.2009.098343. M3 - Article. VL - 65. SP - 315. EP - 319. JO - Journal of Epidemiology & Community Health. JF - Journal of Epidemiology & Community Health. SN - 0143-005X. ER - ...
PURPOSE: In this study we examined whether high glycemic index (GI) and glycemic load (GL) diets are associated with increased risk of developing coronary heart disease (CHD) in Whites and African Americans with and without type 2 diabetes.METHODS: Data on 13,051 patients ages 45 to 64 years from the Atherosclerosis Risk in Communities study were analyzed. The ARIC food frequency questionnaire baseline data provided GI and GL indices. A propensity score was created to estimate the effect of a patients covariates on energy-adjusted GI or GL. During a maximum of 17 years of follow-up, 1683 cases of CHD (371 with diabetes and 1312 without diabetes) were recorded.RESULTS: For every 5-units increase in GI, there was a 1.16-fold (95% confidence interval [95% CI], 1.01-1.33) increased risk of incident CHD in African Americans. For every 30-units increase in GL, there was a 1.11-fold (95% CI, 1.01-1.21) increased risk of incident CHD in Whites. High GL was an especially important CHD risk factor for ...
Design, setting and participants: A CVD risk-factor survey was carried out in rural south-eastern Australia from 2004 to 2006. Using a stratified random sample, data for 1116 participants aged 35-74 years were analysed. Applying the Framingham risk equations to risk-factor data, 5-year probabilities of a coronary heart disease event, stroke and cardiovascular event were calculated. The effect of different changes in risk factors were modelled to assess the extent to which cardiovascular diseases can be prevented by changing the risk factors at a population level (population strategy), among the high-risk individuals (high-risk strategy) or both ...
Using mortality data from National Institute of Statistics in Spain, we analyzed trends of infectious disease mortality rates in Spain during 1980-2011 to provide information on surveillance and control of infectious diseases. During the study period, 628,673 infectious disease-related deaths occurred, the annual change in the mortality rate was −1.6%, and the average infectious disease mortality rate was 48.5 deaths/100,000 population. Although the beginning of HIV/AIDS epidemic led to an increased mortality rate, a decreased rate was observed by the end of the twentieth century. By codes from the International Classification of Diseases, 9th revision, the most frequent underlying cause of death was pneumonia. Emergence and reemergence of infectious diseases continue to be public health problems despite reduced mortality rates produced by various interventions. Therefore, surveillance and control systems should be reinforced with a goal of providing reliable data for useful decision making.
Methods and Apparatus for Segregation of Particles | Nanopore Detection of Small Molecules Through Competition Assays | DETECTION OF THERMAL DAMAGE OF COMPOSITES USING MOLECULAR PROBES | WATER QUALITY SENSOR SUITABLE FOR AUTOMATED PRODUCTION | Lanthanide-Doped Nanoparticle Compositions for Detecting Microorganisms |
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Objective To compare the application effect and cost in intracoronary stent implantation between domestic and imported drug eluting stent. Methods A total of 791 coronary heart disease patients undergoing intracoronary stent implantation were selected in a Grade 3 and first-class hospital in 2013,and they were divided into A group( using domestic drug eluting stent,n = 398) and B group( using imported drug eluting stent,n = 393) according to the types of stents. During the intracoronary stent implantation,patients of A group used Shanghai Minimally-invasive Firebird Ⅱ Drug-eluting Stents,while patients of B group received United States Medtronic Endenvor Drug Eluting Stents. Clinical data,operative success rate,locations of coronary artery lesions,number of implanted stents,clinical outcome,hospitalization related expenses and incidence of complications were compared between the two groups. Results Patients of the two groups completed the operation successfully,the operative success rates of the two
JA Allen, LA Throm; Percutaneous transluminal coronary angioplasty: a new alternative for ischemic heart disease. Crit Care Nurse 1 January 1982; 2 (1): 24-29. doi: https://doi.org/10.4037/ccn1982.2.1.24. Download citation file:. ...
Background This study sought to determine the relation between and discriminative capability of lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) and coronary heart disease (CHD) in a large population of disease-free women.Methods Among participants of the Nurses Health Study who provided a blood sample, there were 421 cases of incident myocardial infarction during 14 years of follow-up. Controls were matched to cases 2:1 using risk set sampling based on age, smoking, and blood draw date.Results After conditioning on the matching factors, Lp-PLA(2) activity was significantly associated with myocardial infarction (relative risk [RR] 2.86 for extreme quartiles, 95% CI 1.98-4.12). Upon additional adjustment for lipid, inflammatory, and clinical risk factors, the RR remained statistically significant (RR 1.75, 95% CI 1.09-2.84). The discriminative capability of Lp-PLA(2) was assessed by comparing the area below the receiver operating characteristic curves for models with and without Lp-PLA(2) ...
Percutaneous transluminal coronary angioplasty (PTCA) is a minimally invasive procedure to open up blocked coronary arteries, allowing blood to circulate unobstructed to the heart muscle. Market Analysis and Insights: Global Percutaneous Translumi
Considerable epidemiological evidence has accumulated regarding the effect of postmenopausal estrogens on coronary heart disease risk. Five hospital-based case-control studies yielded inconsistent but generally null results; however, these are difficult to interpret due to the problems in selecting …
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The market for technologies and products in the treatment of coronary heart disease is forecast to grow from $12.2 billion in 2014 to $22.5 billion in 2021, according to a new study from Smithers.. Treatment of coronary artery disease by interventional cardiology, through angioplasty and stenting, remains competitive in its clinical outcomes and cost compared to traditional coronary artery bypass graft (CABG) and emerging minimally invasive alternatives to CABG. Further, manufacturers have largely eliminated the concerns about late stent thrombosis that caused a market slowdown in stents, as they have aggressively developed technology developments in stents, their composite materials, and coatings.. A new study from Smithers - The Future of Coronary Heart Disease Medical Devices to 2021 - shows the continued demand for these devices as clinically and cost-effective solutions to coronary artery disease. In the largest product area, coronary stents, despite an upwards of 90% penetration of ...
Background. The coronary risk in diabetes (CoRDia) trial (n = 211) compares the effectiveness of usual diabetes care with a self-management intervention (SMI), with and without personalised risk information (including genetics), on clinical and behavioural outcomes. Here we present an assessment of randomisation, the cardiac risk genotyping assay, and the genetic characteristics of the recruits.. Methods. Ten-year coronary heart disease (CHD) risk was calculated using the UKPDS score. Genetic CHD risk was determined by genotyping 19 single nucleotide polymorphisms (SNPs) using Randoxs Cardiac Risk Prediction Array and calculating a gene score (GS). Accuracy of the array was assessed by genotyping a subset of pre-genotyped samples (n = 185).. Results. Overall, 10-year CHD risk ranged from 2-72 % but did not differ between the randomisation groups (p = 0.13). The array results were 99.8 % concordant with the pre-determined genotypes. The GS did not differ between the Caucasian participants in the ...
In the present study of older community-dwelling individuals, Lp-PLA2 levels were significantly higher in those who developed CHD compared with those who did not. Associations between Lp-PLA2 and LDL, HDL, total cholesterol, and triglycerides were especially strong, and the magnitude of the correlations was in good agreement with previous studies (7,19). Despite these associations, Lp-PLA2 remained a strong and independent predictor of fatal and nonfatal CHD events, over and above these and other traditional risk factors. Thus, Lp-PLA2 added information to lipid and lipoprotein prediction of future CHD and may identify subpopulations at risk for CHD who would not be identified otherwise.. A similar independent association of Lp-PLA2 with CHD risk was reported in the younger participants from the WOSCOPS (5) and ARIC (7,19) studies and in a nested case-control study from the Rotterdam study (9). We now confirm these results for the first time in a cohort of apparently healthy older men and women ...
Finland has marked regional differences in the occurrence of coronary heart disease (CHD). Although the causes for these differences in CHD mortality and morbidity in the Finnish population are unknown, it offers an excellent opportunity to investigate the effects of non-insulin-dependent diabetes mellitus (NIDDM) on CHD risk in two populations differing significantly with respect to the occurrence of CHD. Therefore, we carried out a 7-year prospective population-based study including a large number of patients with NIDDM (East Finland: 253 men and 257 women; West Finland: 328 men, 221 women) and corresponding non-diabetic subjects (East Finland: 313 men, 336 women; West Finland: 325 men, 399 women). In both study populations the presence of NIDDM increased significantly the risk for CHD events (CHD mortality or all CHD events including CHD mortality or non-fatal myocardial infarction). Diabetic men had 3-4 fold higher and diabetic women 8-11-fold higher risk for CHD than corresponding non-diabetic
Subclinical heart disease has been reported to be an independent predictor of CAD risk in the general population. Women with subclinical disease were at greater risk for acute MI.47 Early investigation for CAD in the preclinical stage in young women with SLE is justified because cardiovascular events are an important cause of morbidity and mortality in this population. Published reports show that coronary disease (angina pectoris or acute MI) is more common in women with SLE than in the general population. Moreover, the mean age of patients with SLE who had coronary disease was younger than seen in the general population.4. We studied patients with more than five years of SLE, who had used steroids for at least one year, in attempt to evaluate patients at a greater risk for CAD.10-11,16,48 We analysed only asymptomatic patients, because we wanted to investigate subclinical heart disease. We also excluded patients older than 55 years, because women after this age have higher risk for CAD than ...
Coronary heart disease (CHD) is a disease in which a waxy substance called plaque builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart muscle. You can read more information on this at the National Heart Lung and Blood Institute website.. We had this requirement come in from a partner on how we could store all the patient vital data within Dynamics 365 and calculate a risk score. Our example shows how to use North52s business rules engine for Dynamics 365 to set up a Multi-Sheet Decision Table to evaluate the patients risk score of Coronary Heart Disease.. Each Decision Table Sheet will evaluate specific Risk Factors with a variety of Conditions and decide if that risk factor applies to the patient. A final Decision Table Sheet will then provide a Risk Score based on the individual Risk Factors.. For this article it is assumed that you have at least basic familiarity with Decision Tables and/or have read the following articles:. ...
A cornerstone of conventional dietary advice is the recommendation to replace saturated fatty acids (SFA) with mostly n-6 polyunsaturated fatty acids (PUFA) to reduce the risk of coronary heart disease (CHD). Many clinical trials aimed to test this advice and have had their results pooled in several meta-analyses. However, earlier meta-analyses did not sufficiently account for major confounding variables that were present in some of those trials. Therefore, the aim of the study was to account for the major confounding variables in the diet heart trials, and emphasise the results from those trials that most accurately test the effect of replacing SFA with mostly n-6 PUFA.. Design Clinical trials were identified from earlier meta-analyses. Relevant trials were categorised as adequately controlled or inadequately controlled depending on whether there were substantial dietary or non-dietary differences between the experimental and control groups that were not related to SFA or mostly n-6 PUFA ...
Coronary heart disease (CHD) is the most common cause of death and disability in the United Kingdom. It causes around 94,000 deaths in the UK each year and around one in five men and one in seven women will die from the disease.. Coronary heart disease is usually caused by atherosclerosis, where fatty deposits (atheroma) develop in the walls of the arteries. Atherosclerosis causes symptoms when it partially or completely blocks the arteries that supply the heart muscle with blood. This manifests as a number of conditions including stable angina (where atheroma restricts blood flow) and acute coronary syndromes (where clot formation occurs on the atheroma and causes an abrupt narrowing or complete blockage of the artery). These are described in the relevant sections.. There are two ways to improve blood flow to heart muscle when the arteries become blocked. Percutaneous Coronary Intervention (PCI) and surgical coronary artery bypass grafting (CABG).. PCI is performed under local anaesthetic. A ...
Coronary artery disease[edit]. The primary health risk identified for trans fat consumption is an elevated risk of coronary ... November 1997). "Dietary fat intake and the risk of coronary heart disease in women". The New England Journal of Medicine. 337 ... "Trans fatty acids and coronary heart disease". Archived from the original on 3 September 2006. Retrieved 14 September 2006.. ... Ascherio A, Katan MB, Zock PL, Stampfer MJ, Willett WC (June 1999). "Trans fatty acids and coronary heart disease". The New ...
Coronary artery disease[edit]. The primary health risk identified for trans fat consumption is an elevated risk of coronary ... Hu, FB (1997). "Dietary fat intake and the risk of coronary heart disease in women". New England Journal of Medicine (PDF). , ... "Trans fatty acids and coronary heart disease". Archived from the original on 3 September 2006. Retrieved 14 September 2006.. ... Oh, K.; Hu, F.B.; Manson, J.E.; Stampfer, M.J.; Willett, W.C. (2005). "Dietary fat intake and risk of coronary heart disease in ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... In people without underlying heart disease and who do not have any symptoms, bigeminy in itself does not require any treatment ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... However, recent advancements of technologies have increased the diagnosis of the disease. This disease has multiple types ... Echocardiography, can be used to help physicians with diagnosis, however, it can only be used for the suggesting of the disease ... The multisystemic disease was often misdiagnosed, with diagnosis previously occurring after death during the autopsy. ...
James, TN (Dec 1965). "Anatomy of the coronary arteries in health and disease". Circulation. 32 (6): 1029. doi:10.1161/01.cir. ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... Cases of Diseases of the Heart, Accompanied with Pathological Observations. Dublin Hospital Reports, 1827, 4: 353-453. ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... Disease, such as sinus venosis and atrial defects.[8][9]. *SA node dysfunction, (1st degree block) which can cause the rate of ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... "Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease. 4 (9). ISSN 2047-9980. PMC 4599506 . ... Sometimes the PACs can indicate heart disease or an increased risk for other cardiac arrhythmias. In this case the underlying ... "Holter monitor findings in asymptomatic male military aviators without structural heart disease". Aviat Space Environ Med. 72 ( ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... It is sometimes associated with digitalis toxicity in patients with heart disease. ... that is particularly common in older people and is associated with exacerbations of chronic obstructive pulmonary disease (COPD ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... Wilson's disease, Huntington's disease, abetalipoproteinemia, Fahr disease, biotin-thiamine-responsive basal ganglia disease ... Movements cease during sleep, and the disease usually resolves after several months. Unlike in Huntington's disease, which is ... "Archives of Disease in Childhood. 90 (5): 507-11. doi:10.1136/adc.2004.057679. PMC 1720385. PMID 15851434.. ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... Type 1 Second-degree AV block, also known as Mobitz I or Wenckebach periodicity, is almost always a disease of the AV node. ... Type 2 Second-degree AV block, also known as Mobitz II, is almost always a disease of the distal conduction system (His- ... and chronically in ischemic heart disease and other structural diseases (amyloidosis, mitral valve prolapse, aortic valve ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... Protozoan (Trypanosoma cruzi causing Chagas disease and Toxoplasma gondii). *Bacterial (Brucella, Corynebacterium diphtheriae, ... "Archives of Disease in Childhood. 89 (6): 580-4. doi:10.1136/adc.2003.034686. PMC 1719952. PMID 15155409.. ... Cunha, Burke A. (2009). Infectious Diseases in Critical Care Medicine. CRC Press. p. 263. ISBN 9781420019605. . Archived from ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... Tricuspid Valve Stenosis is a valvular heart disease that narrows the opening of the heart's tricuspid valve. It is a ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... Right axis deviation (,90 degrees) in presence of disease capable of causing RVH ...
Coronary disease. *Coronary artery disease (CAD). *Coronary artery aneurysm. *Spontaneous coronary artery dissection (SCAD) ... there is data to suggest an association between Libman-Sacks endocarditis and a higher risk for embolic cerebrovascular disease ... "Libman-Sacks endocarditis and embolic cerebrovascular disease". Cardiovascular Imaging. 6 (9): 973-983. doi:10.1016/j.jcmg. ...
"Coronary Heart Disease". Weitz & Luxenberg P.C. Archived from the original on May 30, 2013. Retrieved March 20, 2013.. ... Cardiovascular disease associated with COX-2 inhibitors (i.e. Vioxx)[15]. *Deafness and kidney failure associated with ... "Centers for Disease Control and Prevention (CDC). 2018-07-12. Archived from the original on March 17, 2017. Retrieved March 20, ... A headache in a patient taking medication for influenza may be caused by the underlying disease or may be an adverse effect of ...
Poehlman, Eric T. (1998). "Abdominal Obesity: The Metabolic Multi-risk Factor". Coronary Heart Disease. Exp. 9 (8): 469-471. ... Central obesity is positively associated with coronary heart disease risk in women and men. It has been hypothesized that the ... Wingard DL (1990). "Sex differences and coronary heart disease. A case of comparing apples and pears?". Circulation. 81 (5): ... Barrett-Connor E (1997). "Sex differences in coronary heart disease. Why are women so superior? The 1995 Ancel Keys Lecture". ...
Coronary Artery Disease. 23 (6): 368-374. doi:10.1097/MCA.0b013e3283564930. PMID 22735090. Oliveira, André G.; Marques, Pedro E ... In Alzheimer's disease (AD), the expression of A1 and A2A receptors in the frontal cortex of the human brain is increased, ... Following tissue injury in patients with Graft-versus-host disease (GVHD), ATP is released into the pertioneal fluid. It binds ... Istradefylline - Antagonist of the adenosine A2A receptor, used in the treatment of Parkinson's disease as an adjunct to L-DOPA ...
Coronary heart disease events. ( non-fatal myocardial infarction. , death. ). 1.29 (1.02-1.63). 1.32 (1.02-1.72). 1.18 (0.70- ... The WHI reported statistically significant increases in rates of breast cancer, coronary heart disease, strokes and pulmonary ... A subset of the events was combined in a "global index", defined as the earliest occurrence of coronary heart disease events, ... The risks of coronary heart disease with HRT vary depending on age and time since menopause. ...
CHDS1: Coronary heart disease, susceptibility to, 1. *CIAPIN1: Anamorsin (originally, Cytokine induced apoptosis inhibitor 1) ... Gilbert F (1999). "Disease genes and chromosomes: disease maps of the human genome. Chromosome 16". Genet Test. 3 (2): 243-54. ... PKDTS: Polycystic kidney disease, infantile severe, with tuberous sclerosis. *PMFBP1: encoding protein Polyamine-modulated ...
Lands, B (Jul 2009). "Planning primary prevention of coronary disease". Curr Atheroscler Rep. 11 (4): 272-80. doi:10.1007/ ... 2012 Noa Noy from Case Western Reserve University on retinoic acid signaling in metabolic diseases ...
1980). Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease. Harvard University Press. ISBN ... Keys, Ancel (1980). Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease. Harvard University Press. ... Keys, Ancel (1975). "Coronary Heart Disease - The Global Picture". Atherosclerosis. 22 (2): 149-192. doi:10.1016/0021-9150(75) ... Keys, Ancel (1971). "Sucrose in the Diet and Coronary Heart Disease". Atherosclerosis. 14 (2): 193-202. doi:10.1016/0021-9150( ...
Cardiovascular disease and coronary heart disease. The Harvard School of Public Health recommends consumers eat red meat ... concluding that dietary saturated fat is associated with an increased risk of coronary heart disease or cardiovascular disease ... "Red and Processed Meat Consumption and Risk of Incident Coronary Heart Disease, Stroke, and Diabetes Mellitus: A Systematic ... is associated with higher incidence of coronary heart disease and diabetes mellitus."[78] ...
Associated adult diseases of the fetus due to IUGR include, but are not limited to, coronary artery disease (CAD), type 2 ... Pre-eclampsia can mimic and be confused with many other diseases, including chronic hypertension, chronic renal disease, ... "Fetal origins of coronary heart disease". British Medical Journal. 311 (6998): 171-74. doi:10.1136/bmj.311.6998.171. PMC ... The fetal origins hypothesis states that fetal undernutrition is linked with coronary heart disease later in adult life due to ...
95P-0197; RIN 0910-AA19; Food Labeling: Health Claims; Oats and Coronary Heart Disease" (PDF). US Food and Drug Administration ... coronary) heart disease pursuant to Article 14 of Regulation (EC) No 1924/2006". EFSA Journal. 8 (12): 1885. doi:10.2903/j.efsa ... ruling by the Food and Drug Administration that consuming oat bran or whole rolled oats can lower the risk of heart disease ...
Cornelis MC, El-Sohemy A (November 2007). "Coffee, caffeine, and coronary heart disease". Curr Opin Clin Nutr Metab Care. 10 (6 ...
"Intercessory Prayer and Cardiovascular Disease Progression in a Coronary Care Unit Population: A Randomized Controlled Trial". ... while imbalance results in disease. Such disease-inducing imbalances can be adjusted and balanced using traditional herbs, ... A belief that a substance that causes the symptoms of a disease in healthy people cures similar symptoms in sick people.[n 8] ... Treatments for severe diseases such as cancer and HIV infection have well-known, significant side-effects. Even low-risk ...
Acceleration of Atherosclerosis After Lactobacillus casei-Induced Coronary Arteritis in a Mouse Model of Kawasaki Disease, ... Nerve growth factor circulating levels are increased in Kawasaki disease: correlation with disease activity and reduced ...
Rosenbloom J (1984). «Elastin: relation of protein and gene structure to disease». Lab. Invest. 51 (6): 605-23. PMID 6150137. ... 2009). «Integrative predictive model of coronary artery calcification in atherosclerosis». Circulation. 120 (24): 2448-54. PMC ... 2009). «Association of genetic variants with chronic kidney disease in individuals with different lipid profiles». Int. J. Mol ... 2010). «Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease». Gastroenterology. 139 (1): ...
... coronary heart disease, and cerebrovascular disease, because they ate mostly lean meats and plants and frequently engaged in ... caused by other factors such as disease and overhunting by humans.[16][17] New research suggests that the extinction of the ... It is also unlikely that Paleolithic hunter-gatherers were affected by modern diseases of affluence such as type 2 diabetes, ... "Hunter-gatherer diets: wild foods signal relief from diseases of affluence (PDF)" (PDF). In Ungar, Peter S.; Teaford, Mark F. ...
2008). "Newly identified loci that influence lipid concentrations and risk of coronary artery disease". Nat. Genet. 40 (2): 161 ... "Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk". Hum. Mol. Genet. 18 ... haplotypes and lipid levels in prospective Coronary Heart Disease Risk among UK healthy men". Molecular medicine (Cambridge, ...
Mandel SJ, Brent GA, Larsen PR (September 1993). "Levothyroxine therapy in patients with thyroid disease". Annals of Internal ... starting at higher doses may cause acute coronary syndrome or an arrhythmia.[11] ... For older people (over 50 years old) and people with known or suspected ischemic heart disease, levothyroxine therapy should ... Levothyroxine is also used as interventional therapy in people with nodular thyroid disease or thyroid cancer to suppress ...
There is an increased risk of coronary heart disease. Cardiomyopathy and muscular dystrophy may occur rarely. Xanthoma and nail ... 2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. Herbst KL, Tannock LR, Deeb ...
A 2009 report by the Institute of Medicine concluded that smoking bans reduced the risk of coronary heart disease and heart ... An epidemiology report says that the risk of coronary heart disease is increased to around 25-30% when one is exposed to ... heart disease and other smoking related diseases") See also WHO Framework Convention on Tobacco Control; First international ... which include an increased risk of heart disease, cancer, emphysema, and other diseases. Laws implementing bans on indoor ...
... such as diverticulitis and acute coronary syndrome.[36][106] Diagnosis of late-stage Lyme disease is often complicated by a ... "Lyme disease rashes and look-alikes". Lyme Disease. Centers for Disease Control and Prevention. 21 December 2018. Archived from ... "Lyme Disease Data and surveillance". Lyme Disease. Centers for Disease Control and Prevention. 5 February 2019. Archived from ... Treatment regimens for Lyme disease range from 14 days in early localized disease, to 14-21 days in early disseminated disease ...
Significant diseases. Cancer, bone fractures. Significant tests. screening tests, X-ray, CT, MRI, PET, bone scan, ...
House, J.S. (1974). Occupational stress and coronary heart disease: A review and theoretical integration. Journal of Health and ... Cardiovascular disease[edit]. Main articles: Occupational stress and Cardiovascular disease. Research has identified health- ... 2017). Effort-reward imbalance at work and incident coronary heart disease: A multi-cohort study of 90,164 individuals. ... Toker, S., Melamed, S., Berliner, S., Zeltser, D., & Shapira, I. (2012). Burnout and risk of coronary heart disease: a ...
2006). "Low-carbohydrate-diet score and the risk of coronary heart disease in women". N. Engl. J. Med. 355 (19): 1991-2002. doi ... "Can lifestyle changes reverse coronary heart disease? The Lifestyle Heart Trial". Lancet. 336 (8708): 129-133. doi:10.1016/0140 ... found that low carbohydrate diets based on vegetable sources of fat and protein are associated with less coronary heart disease ... between animal fat intake and coronary heart disease (table 4). A long term study that monitored 43,396 Swedish women however ...
... and blood pressure in those with coronary heart disease (CHD).[37]. StrokeEdit. Music is useful in the recovery of motor skills ... "Music for stress and anxiety reduction in coronary heart disease patients". The Cochrane Database of Systematic Reviews (12): ... Heart diseaseEdit. According to a 2013 Cochrane review, listening to music may improve heart rate, respiratory rate, ... Aesculapius was said to cure diseases of the mind by using song and music, and music therapy was used in Egyptian temples. ...
... and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants.. ... Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: A systematic review ... A.M.A. Recognizes Obesity as a Disease. New York Times. 2013-06-18 [2015-11-19]. (原始内容存档于2013-06-23).. ... Centers for Disease Control and Prevention. 2007-05-22 [2007-09-05]. (原始内容存档于2007-10-
Soluble fiber from certain foods and risk of coronary heart disease (CHD).[3] ... Soluble fiber from certain foods and risk of coronary heart disease (CHD) ... 3.0 g of β-glucan from oats per day decreased absorption of dietary cholesterol and reduced the risk of coronary heart disease ... Zeković, Djordje B. (10 October 2008). "Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation". ...
Other uncommon causes are Trousseau disease,[medical citation needed] Beurger's disease (Thromboangiitis obliterans),[medical ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... One in five of the middle-aged (65-75 years) population of the United Kingdom have evidence of peripheral arterial disease on ... It is classically associated with early-stage peripheral artery disease, and can progress to critical limb ischemia unless ...
Natural history of coronary disease with and without aortocoronary by-pass operation. Survival curves of 272 patients over a ... Some diseases associated with mutations in the TATA box include gastric cancer, spinocerebellar ataxia, Huntington's disease, ... Diseases[edit]. Mutations in the TATA box region affects the binding of the TATA-binding protein (TBP) for transcription ... "The American Review of Respiratory Disease. 118 (3): 635-6. doi:10.1128/mcb.10.8.3859. PMC 360896. PMID 2196437.. ...
By this time, he was suffering from chronic coronary disease. A trip to Crimea for treatment in 1915 failed to ameliorate the ...
PCOS, coronary heart disease, stroke and the influence of obesity: a systematic review and meta-analysis. Hum. Reprod. Update. ... Polycystic ovarian disease: heritability and heterogeneity. Hum. Reprod. Update. 2001, 7 (1): 3-7. PMID 11212071. doi:10.1093/ ... Imaging in Polycystic Ovary Disease. eMedicine. eMedicine. 20 April 2011 [19 November 2011].. ... Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the ...
... which is the principal cause of coronary heart disease and other forms of cardiovascular disease. In contrast, HDL particles ( ... "Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention ... This disease process leads to myocardial infarction (heart attack), stroke and peripheral vascular disease. Since higher blood ... liver diseases, and mental diseases. This result indicates that the low cholesterol effect occurs even among younger ...
... coronary heart disease, dimension, osteoporosis, eye disease, stroke cancer and rheumatoid arthritis and the influence of ... coronary heart disease and strokes strong conclusive evidence of the correlation between fruit and vegetable intake and the ... The Centers for Disease Control and Prevention (2014). Children eating more fruit, but fruit and vegetable intake still too low ... Development of chronic disease has become closely related to the consumption of fruits and vegetables throughout childhood ( ...
Role in disease[edit]. Few congenital disorders of the fibrinolytic system have been documented. Nevertheless, excess levels of ... They are given following a heart attack to dissolve the thrombus blocking the coronary artery; experimentally after a stroke to ... Such results can be seen in peoples with liver disease, PAI-1 deficiency or alpha 2-antiplasmin deficiency. Similar results are ... The fibrinolytic system is closely linked to control of inflammation, and plays a role in disease states associated with ...
... and coronary arteries.[8] to cause a reduction in systemic vascular resistance. Fenoldopam has a rapid onset of action (4 ... in theory it could be beneficial in hypertensive patients with concomitant chronic kidney disease.[citation needed] ...
Kaumann AJ (June 1983). "Yohimbine and rauwolscine inhibit 5-hydroxytryptamine-induced contraction of large coronary arteries ... treatment or prevention of disease": 21 U.S.C. § 321(g)(1)(B).[23] However the legal position is not entirely straightforward,[ ...
... and a coronary sinus lead (red arrow). The coronary sinus lead wraps around the outside of the left ventricle, enabling pacing ... Lidwell M C, "Cardiac Disease in Relation to Anaesthesia" in Transactions of the Third Session, Australasian Medical Congress, ... sinus node disease (SND) or sick sinus syndrome. Where the problem is atrioventricular block (AVB) the pacemaker is required to ... and another passing through the vena cava and the right atrium and inserted through the coronary sinus to pace the epicardial ...
... reduction in death from coronary heart disease to a point where people are no more likely to die of coronary heart disease than ... The most common problem in FH is the development of coronary artery disease (atherosclerosis of the coronary arteries that ... However, if the person already had coronary heart disease the reduction was 25%. The results emphasize the importance of early ... June 1998). "Effective lipid modification by partial ileal bypass reduced long-term coronary heart disease mortality and ...
Indians are at particularly high risk for atherosclerosis and coronary artery disease. This may be attributed to a genetic ... Diarrheal diseases are the primary causes of early childhood mortality. These diseases can be attributed to poor sanitation and ... Diseases such as dengue fever, hepatitis, tuberculosis, malaria and pneumonia continue to plague India due to increased ... The provision of clean drinking water and sanitation as one of the principal factors in control of diseases is well established ...
This process is undergoing pre-clinical trials in humans and may be used to treat patients suffering coronary heart disease, ... This 'Grow Your Own Arteries' technique is helping patients survive coronary heart disease, renal failure and other life- ... in heart diseases). She further determined how these cells could be maintained in the 'non-disease' phenotype. This knowledge ... definition of single transduction pathways through which factors act to enhance vascular disease regression and prevent disease ...
Soluble fiber from certain foods and risk of coronary heart disease (CHD) (revision 2015)". US Department of Health and Human ... Celiac diseaseEdit. Main articles: Oat sensitivity and Gluten-related disorders. Celiac disease (coeliac disease) is a ... Pests and diseasesEdit. Oats are relatively free from diseases and pests with the exception being leaf diseases, such as leaf ... 2009). Introduction of oats in the diet of individuals with celiac disease: a systematic review. Adv Food Nutr Res (Systematic ...
Coronary artery disease. Synonyms. Atherosclerotic heart disease,[1] atherosclerotic vascular disease,[2] coronary heart ... Coronary artery disease (CAD), also known as ischemic heart disease (IHD),[13] refers to a group of diseases which includes ... Stable coronary artery disease (SCAD) is also often called stable ischemic heart disease (SIHD).[59] A 2015 monograph explains ... Typically, coronary artery disease occurs when part of the smooth, elastic lining inside a coronary artery (the arteries that ...
... is a cardiovascular disease in which there is a failure of coronary circulation to supply adequate ... caused by a decreased capacity of the coronary vessels., Narrowing of the coronary arteries due to fatty deposits inside the ... An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood ... Coronary Artery Disease, Diseases, Coronary, CORONARY HEART DIS, Coronary Diseases, Disease, Coronary Heart, Coronary Disease, ...
Learn what causes coronary artery disease (CAD) and how it is diagnosed. Get the facts from the CDC. ... What is coronary artery disease?. Coronary artery disease (CAD) is the most common type of heart disease in the United States. ... Learn the facts about heart disease, including coronary artery disease, the most common type of heart disease. ... How is coronary artery disease diagnosed?. If youre at high risk for heart disease or already have symptoms, your doctor can ...
Coronary heart disease (CHD) is a major cause of death both in the UK and worldwide. CHD is sometimes called ischaemic heart ... Find out more about diagnosing coronary heart disease. Treating coronary heart disease (CHD). Coronary heart disease cannot be ... Causes of coronary heart disease (CHD). Coronary heart disease is the term that describes what happens when your hearts blood ... Diagnosing coronary heart disease (CHD). If your doctor feels youre at risk of CHD, they may carry out a risk assessment. ...
Coronary artery disease is the buildup of plaque on the inside of the coronary arteries, the blood vessels that supply oxygen ... depends upon how far the disease has already progressed. ... Articles OnCoronary Artery Disease. Coronary Artery Disease ... Lifestyle changes are the first step for anyone with coronary artery disease. Healthy habits can slow or even stop the disease ... Heart Disease: Should I Have Angioplasty for Stable Angina? Heart Disease: Should I Have Bypass Surgery? ...
Coronary Artery Disease Definition Coronary artery disease is a narrowing or blockage of the arteries and vessels that provide ... Coronary artery disease, also called coronary heart disease or heart disease, is the leading cause of death for both men and ... Coronary heart disease also may be called coronary artery disease or simply heart disease. It is the leading cause of death in ... Coronary artery disease, also called coronary heart disease or atherosclerotic heart disease, is the leading cause of death for ...
Health Information on Coronary Artery Disease: MedlinePlus Multiple Languages Collection ... Coronary Artery Disease: MedlinePlus Health Topic - English Enfermedad de las arterias coronarias: Tema de salud de MedlinePlus ... Coronary Artery Disease (CAD) - 简体中文 (Chinese, Simplified (Mandarin dialect)) Bilingual PDF ... Coronary Artery Disease (CAD) - 繁體中文 (Chinese, Traditional (Cantonese dialect)) Bilingual PDF ...
Coronary heart disease (CHD) is also called coronary artery disease. ... Coronary heart disease is a narrowing of the small blood vessels that supply blood and oxygen to the heart. ... Heart disease, Coronary heart disease, Coronary artery disease; Arteriosclerotic heart disease; CHD; CAD ... Coronary heart disease is a narrowing of the small blood vessels that supply blood and oxygen to the heart. Coronary heart ...
Prevention of Coronary Disease. Br Med J 1969; 1 doi: https://doi.org/10.1136/bmj.1.5637.182 (Published 18 January 1969) Cite ...
Although coronary heart disease (CHD) cannot be cured, treatment can help manage the symptoms and reduce the risk of further ... Coronary angioplasty. Coronary angioplasty is also known as percutaneous coronary intervention (PCI), percutaneous transluminal ... Treatment for coronary heart disease (CHD) can help manage the symptoms and reduce the risk of further problems. ... Coronary artery bypass graft. Coronary artery bypass grafting (CABG) is also known as bypass surgery, a heart bypass, or ...
... disease characterized by an inadequate supply of oxygen-rich blood to the heart muscle (myocardium) because of narrowing or ... blocking of a coronary artery by fatty plaques (see atherosclerosis). If the oxygen depletion is extreme, the effect may be a ... ischemic heart disease. Coronary heart disease, also called coronary artery disease or ischemic heart disease, disease ... cardiovascular disease: Coronary heart disease. Coronary heart disease is a general term for a number of syndromes. Ischemic ...
Coronary artery disease is a widespread problem and claims millions of lives worldwide every year. The condition has severe ... www.escardio.org/.../...Stable_Coronary_Artery_Disease_web_addenda.pdf. *www.nhs.uk/Conditions/Coronary-heart-disease/Pages/ ... Coronary artery bypass grafting (CABG). Medical management of coronary artery disease. Various drugs are available that can ... Coronary Artery Disease Treatment. News-Medical. 30 July 2021. ,https://www.news-medical.net/health/Coronary-Artery-Disease- ...
Coronary artery disease describes a condition where the coronary arteries that supply the heart with oxygen and nutrients ... www.escardio.org/.../...Stable_Coronary_Artery_Disease_web_addenda.pdf. *www.nhs.uk/Conditions/Coronary-heart-disease/Pages/ ... Patients with coronary artery disease may have one or more plaques in their coronary arteries and unless the blockages are ... Coronary artery disease describes a condition where the coronary arteries that supply the heart with oxygen and nutrients ...
Coronary artery disease affects the arteries that supply the heart muscle with blood. Although it can be life-threatening, it ... Coronary artery disease (CAD) happens so often you probably know someone who has it. Its the most common type of heart disease ... Coronary artery disease (CAD) becomes more likely as you get older or if it runs in your family. But you can manage many other ... Coronary artery bypass grafting is a type of surgery in which doctors use blood vessels from other parts of your body to make a ...
This results in coronary heart disease, the most common type of heart disease in the United States. Here, we cover causes, ... The coronary arteries supply oxygen and blood to the heart. However, when cholesterol builds up on the artery walls, they can ... Coronary heart disease (CHD), or coronary artery disease, develops when the coronary arteries become too narrow. The coronary ... CHD is the most dangerous cardiovascular disease, as it causes the most deaths of any heart disease in the United States. ...
Prevention of coronary heart disease. BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7436.404-a (Published 12 February 2004 ...
Coronary Artery Disease (CAD). Coronary artery disease is also called CAD. It is the most common form of heart disease in the U ... Coronary artery disease (CAD) is the most common form of heart disease in the U.S. Its also the leading cause of death. It ... occurs when the coronary arteries (blood vessels) that carry blood away from your heart get blocked with plaque. Over time, ...
... or coronary heart disease, can lead to heart attack or death. Learn what causes this condition and how you can prevent it. ... What is coronary artery disease?. Coronary artery disease (CAD), also called coronary heart disease, is the most common type of ... Heart disease is one type of cardiovascular disease. Per the World Health Organization (WHO). , cardiovascular diseases are the ... Tips for preventing coronary artery disease. You can make many lifestyle changes to decrease your risk of developing CAD and ...
Coronary heart disease (CHD)-also sometimes called coronary artery disease-is the most common form of cardiovascular disease, a ... Coronary heart disease (CHD)-also sometimes called coronary artery disease-is the most common form of cardiovascular disease, a ... Who Gets Coronary Heart Disease?. More than 16 million Americans suffer from CHD. Despite significant declines in the rate of ... Coronary heart disease is generally due to the buildup of plaques in the arterial walls, a process known as atherosclerosis. ...
Can Mental Stress Lead to Heart Disease? Can depression and anxiety cause heart disease? Get the facts in this Missouri ... CORONARY ANGIOGRAPHY venothini My mother has small pain in below chest and back of chest, then doctor advise to go for an ... CORONARY ANGIOGRAPHY. My mother has small pain in below chest and back of chest, then doctor advise to go for an angiogram, ... 8. PDA&PLV: minimal disease Please advise us for further treatment, whether it can be cure with tablets and exercise or have to ...
Find Coronary Artery Disease information, treatments for Coronary Artery Disease and Coronary Artery Disease symptoms. ... MedHelps Coronary Artery Disease Center for Information, Symptoms, Resources, Treatments and Tools for Coronary Artery Disease ... condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or ...
Number of deaths and age-adjusted death rates* from persons within coronary heart disease† and stroke§ by sex, age, and race/ ... Continued) Number of deaths and age-adjusted death rates* from persons within coronary heart disease† and stroke§ by sex, age, ... Coronary heart disease (CHD) is the cause of more than two-thirds of all heart disease-related deaths (1,2). One of the Healthy ... Coronary heart disease and stroke deaths-United States, 2006. In: CDC. CDC health disparities and inequalities report. MMWR ...
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy ...
... Coronary arteries supply oxygen-rich blood to the heart muscle. Coronary artery disease results from ... Common symptoms of coronary artery disease include shortness of breath and angina (pain or a feeling of increased pressure in ... Hybrid minimally invasive coronary artery bypass and coronary artery stent placement. Learn about minimally invasive procedures ... When a coronary artery suddenly becomes blocked and blood flow to an area of heart muscle stops, it is called a heart attack. A ...
Coronary artery disease and rheumatoid arthritis.. Goodson N1.. Author information. 1. Arthritis Research Campaign, ... It is not clear why rheumatoid patients have higher rates of coronary disease. Traditional cardiovascular risk factors do not ... It may be that these new cardiovascular risk factors are responsible for accelerating coronary heart disease in patients with ... This article reviews recent literature relating to the epidemiology of cardiovascular disease in the context of RA. ...
Extracellular vesicles in coronary artery disease.. Boulanger CM1,2, Loyer X1,2, Rautou PE1,3,4, Amabile N1,5. ... This Review summarizes current knowledge on the role of extracellular vesicles in coronary artery disease, and their emerging ... valuable biological information for biomarker discovery in primary and secondary prevention of coronary artery disease. ...
Coronary Heart Disease is plaque buildup in your arteries. Its known as hardening of the arteries, too. Arteries carry blood ... Coronary Artery Disease (CAD). Coronary artery disease is also called CAD. It is the most common form of heart disease in the U ... What is coronary heart disease?. Coronary heart disease (CHD) is the most common type of heart disease. It is also called ... What causes coronary heart disease?. Coronary heart disease develops over time. It occurs as your arteries become blocked from ...
Coronary Heart Disease Polyunsaturated Fatty Acid Fish Consumption Fish Intake Coronary Heart Disease Mortality These keywords ... Fish consumption and mortality from coronary heart disease. N.Eng.J.Med. (1985) 313, 820CrossRefGoogle Scholar ... Keys A.. Coronary heart disease in seven countries. Circulation (1970) 41, Suppl.1-1-211Google Scholar ... Coronary heart disease, serum lipids, platelets and dietary fish in two communities in Northern Norway. Acta Med.Scand. (1987) ...
Get inspiration for Coronary Artery Disease Powerpoint Template. Browse through our huge selection of community templates or ... Heart Disease Scientific Name - Coronary Artery Disease Other Names - Ischemic Heart Disease Prevention Coronary Heart Disease ... Coronary Artery Disease Powerpoint Template. Coronary Artery Disease Powerpoint Template. Create your presentation by reusing a ... Coronary artery Disease. Transcript: Coronary Artery Disease Eating a healthy, balanced diet Regular exercises Maintain a ...
Coronary artery disease (CAD) occurs when these arteries become blocked. CAD, which typically builds up over decades, is the ... most common form of heart disease and is the leading cause of heart disease-related death worldwide. ... Your coronary arteries are the large blood vessels that supply your heart muscle with oxygen-rich blood. ... Coronary Artery Disease Treatment at BIDMC. In some cases, coronary artery disease can be managed with lifestyle changes aimed ...
  • Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. (ebi.ac.uk)
  • Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries). (cdc.gov)
  • CAD is caused by plaque buildup in the walls of the arteries that supply blood to the heart (called coronary arteries) and other parts of the body. (cdc.gov)
  • Health care professionals can measure blood pressure within the heart and the strength of blood flow through the heart's chambers as well as collect blood samples from the heart or inject dye into the arteries of the heart (coronary arteries). (cdc.gov)
  • Monitors blockage and flow of blood through the coronary arteries. (cdc.gov)
  • A computed tomography (CT) scan that looks in the coronary arteries for calcium buildup and plaque. (cdc.gov)
  • Coronary heart disease is the term that describes what happens when your heart's blood supply is blocked or interrupted by a build-up of fatty substances in the coronary arteries. (www.nhs.uk)
  • The heart gets its own supply of blood from a network of blood vessels on the heart's surface called coronary arteries. (www.nhs.uk)
  • Coronary artery disease is a narrowing or blockage of the arteries and vessels that provide oxygen and nutrients to the heart. (encyclopedia.com)
  • Coronary artery disease occurs when the coronary arteries become partially blocked or clogged. (encyclopedia.com)
  • This blockage limits the flow of blood from the coronary arteries, which are the major arteries supplying oxygen-rich blood to the heart. (encyclopedia.com)
  • The coronary arteries expand when the heart is working harder and needs more oxygen. (encyclopedia.com)
  • Healthy coronary arteries are clean, smooth, and slick. (encyclopedia.com)
  • The disease process in arteries is thought to begin with an injury to the linings and walls of the arteries. (encyclopedia.com)
  • Atherosclerotic plaques often form blood clots that also can block the coronary arteries (coronary thrombosis). (encyclopedia.com)
  • Fatty material and other substances form a plaque buildup on the walls of your coronary arteries. (medlineplus.gov)
  • The coronary arteries bring blood and oxygen to your heart. (medlineplus.gov)
  • Coronary angiography -- An invasive test that evaluates the heart arteries under x-ray. (medlineplus.gov)
  • Operations have been devised to bring a new blood supply into the heart when the coronary arteries become narrowed by atherosclerosis. (britannica.com)
  • Coronary artery disease describes a condition where the coronary arteries that supply the heart with oxygen and nutrients become hardened and narrowed. (news-medical.net)
  • Patients with coronary artery disease may have one or more plaques in their coronary arteries and unless the blockages are severe, there may be no symptoms. (news-medical.net)
  • In cases of suspected heart disease, a coronary angiogram may be performed to assess the state of the coronary arteries. (news-medical.net)
  • Coronary heart disease (CHD), or coronary artery disease, develops when the coronary arteries become too narrow. (medicalnewstoday.com)
  • The coronary arteries are the blood vessels that supply oxygen and blood to the heart. (medicalnewstoday.com)
  • Coronary arteries form the network of blood vessels on the surface of the heart that feed it oxygen. (medicalnewstoday.com)
  • Heart attack occurs when the heart muscle does not have enough blood or oxygen, such as when a blood clot develops from plaque in one of the coronary arteries. (medicalnewstoday.com)
  • Calcium channel blockers: These will widen the coronary arteries, improving blood flow to the heart and reducing hypertension . (medicalnewstoday.com)
  • It occurs when the coronary arteries (blood vessels) that carry blood away from your heart get blocked with plaque. (familydoctor.org)
  • The most frequent cause of CAD is injury and plaque buildup in these vessels, which are called coronary arteries. (healthline.com)
  • Healthy coronary arteries have smooth walls through which blood can easily flow. (healthline.com)
  • CHD is a narrowing of the coronary arteries, the vessels that supply oxygenated blood (fuel) to the heart muscle. (healthcentral.com)
  • In CHD, narrowed coronary arteries limit the supply of oxygenated blood to portions of the heart muscle. (healthcentral.com)
  • However, as the disease worsens, the narrowed arteries may starve the heart muscle of oxygen during periods of normal activity, or even at rest. (healthcentral.com)
  • As the disease progresses, chest pain (angina pectoris) may develop during periods of physical activity or emotional stress, because the narrowed arteries cannot supply the heart with the increased amount of blood and oxygen necessary at those times. (healthcentral.com)
  • Coronary arteries supply oxygen-rich blood to the heart muscle. (emoryhealthcare.org)
  • Coronary angiogram checks your arteries for flow and blockage. (familydoctor.org)
  • Your coronary arteries are the large blood vessels that supply your heart muscle with oxygen-rich blood. (bidmc.org)
  • Coronary artery disease (CAD) occurs when these arteries become blocked. (bidmc.org)
  • Coronary artery bypass graft (CABG) surgery (open-heart surgery) is often performed when multiple coronary arteries are blocked or when blockages are not suitable for angioplasty or stenting. (bidmc.org)
  • CABG surgery involves the usage of arteries or veins from other areas in your body to route blood flow around your narrowed coronary arteries. (bidmc.org)
  • If your coronary arteries become partly blocked, it can cause chest pain (angina) . (nidirect.gov.uk)
  • Coronary artery disease (CAD), also known as coronary heart disease (CHD), ischemic heart disease (IHD), or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of plaque in the arteries of the heart. (dbpedia.org)
  • The condition develops when cholesterol-containing deposits build up and narrow the coronary arteries, decreasing blood flow to the heart. (fda.gov)
  • The treatment options this study will compare are: (1) Hybrid Coronary Revascularization [HCR] (a combination of surgery and catheter procedures to open up clogged heart arteries) and (2) Percutaneous Coronary Intervention [PCI] (catheter procedures alone to open up clogged heart arteries). (centerwatch.com)
  • This is a non-randomized, multi-center, prospective, single arm, controlled clinical study to collect information about the safety and effectiveness of the COBRA PzFTM Coronary Stent System in the treatment of de novo stenotic lesions in native coronary arteries. (centerwatch.com)
  • The coronary arteries arise from the aorta , which is adjacent to the heart. (rxlist.com)
  • These stress tests are able to detect the presence of flow-limiting blockages in the coronary arteries, generally in the range of at least a 50% reduction in the diameter of at least one of the three major coronary arteries. (rxlist.com)
  • These are the coronary arteries. (healthgrades.com)
  • In CAD, the coronary arteries become narrow and stiff due to atherosclerosis and inflammation. (healthgrades.com)
  • Coronary artery disease (CAD) causes impaired blood flow in the arteries that supply blood to the heart. (healthline.com)
  • During this procedure, your doctor injects a special dye into your coronary arteries through a catheter inserted through an artery in your groin or forearm. (healthline.com)
  • The dye helps enhance the radiographic image of your coronary arteries to identify any blockages. (healthline.com)
  • You may not know that you're living with growing plaque buildup in the walls of your coronary arteries because you have no symptoms. (heartfoundation.org.au)
  • Coronary artery disease is caused by hardening of the arteries, or atherosclerosis . (rexhealth.com)
  • When it occurs in the ones that supply blood to the heart ( the coronary arteries ), it is called coronary artery disease. (rexhealth.com)
  • When plaque builds up in the coronary arteries, the heart may not get the blood it needs to work well. (rexhealth.com)
  • Coronary artery disease is a build-up of plaque in the arteries, which restricts the flow of oxygen-rich blood and nutrients to the heart. (montgomeryadvertiser.com)
  • Coronary Heart Disease Heart disease is the hardening of arteries that leads to blockages in the arteries What is CHD? (prezi.com)
  • Heart disease is the hardening of the arteries that supply the oxygen to the cardiac muscle Shocking facts about heart disease Collectively, heart diseases cause more than a quarter of all deaths in the UK, accounting for more than 179,000 deaths each year at an estimated cost of £19 billion to the economy. (prezi.com)
  • Social/environmental conditions Heart disease is caused by the blocking of the arteries due to the build up of fatty substances in the coronary arteries that supply the heart with oxygenated blood. (prezi.com)
  • Heart disease is the term used to describe what happens when your hearts blood supply is blocked or interrupted by a build up of fatty substances in the coronary arteries. (prezi.com)
  • MRI can detect thickening in the walls of the arteries, a change that occurs earlier in the course of heart disease than stenosis, or narrowing of the arteries. (prweb.com)
  • It causes increased blood flow to the heart muscle by relaxing the coronary arteries and other blood vessels in the body and regulates heart rhythm. (heart.org)
  • Coronary Artery Disease is the proper term for this condition which is usually caused by atherosclerosis meaning clogging of the arteries by cholesterol and fatty deposits. (empowher.com)
  • He explained that Millie had coronary artery disease - narrowing of the arteries in her heart. (medtronic.com)
  • At first, she assumed that she was headed for another angioplasty procedure, but her cardiologist was concerned about one of her coronary arteries. (medtronic.com)
  • Coronary heart disease is the end result of the accumulation of plaques within the walls of the arteries. (dailystrength.org)
  • The next day, his cardiologist, Dr. Remington, performed a diagnostic cardiac catheterization, which confirmed that Dante had numerous blockages in his coronary arteries. (medtronic.com)
  • Information from the 3D fused image helped correlate specific stenoses, or areas of narrowing in the coronary arteries, and their severity with possible cardiac scar tissue and ischemia--a condition in which parts of the heart muscle don't get enough blood. (eurekalert.org)
  • Typically, advancing atherosclerosis leads to narrowing or occlusion of major coronary arteries and their branches, resulting in angina, heart failure, or myocardial infarction. (ahajournals.org)
  • It occurs when one or more of the coronary arteries becomes narrow or blocked. (heartandstroke.ca)
  • In coronary artery disease, the coronary arteries become narrowed or blocked, which reduces blood flow to the heart. (heartandstroke.ca)
  • Damage or injury to the inner layer of the coronary arteries caused by the risk factors listed above. (heartandstroke.ca)
  • Coronary artery disease (CAD) affects the arteries that deliver blood and oxygen to the heart muscle. (intermountainhealthcare.org)
  • Cholesterol-containing deposits (plaque) in the arteries and inflammation are usually to blame for coronary artery disease. (hubpages.com)
  • The coronary arteries begin to narrow. (denverhealth.org)
  • Sanders, who is one of the leading candidates to challenge President Trump in 2020, underwent emergency surgery to have two stents inserted into one of his coronary arteries that feeds blood to the external muscle of the heart. (sandrarose.com)
  • The illustration shows the positions of the left and right coronary arteries on the external wall of the heart. (sandrarose.com)
  • Coronary stents are typically used to prevent heart attacks in people who are diagnosed with Coronary Artery Disease caused by Atherosclerosis (hardening of the arteries or clogged arteries). (sandrarose.com)
  • Coronary artery disease (CAD), also called ischemic heart disease, occurs due to the narrowing of coronary arteries that supply oxygen-rich blood to the heart. (reportlinker.com)
  • Most of the time, though, when people speak of heart disease what they really mean is coronary artery disease-a narrowing of the coronary arteries. (harvard.edu)
  • New imaging techniques that use light or sound waves to create images of the inside of coronary arteries have helped researchers better understand the fat-laden plaque that builds up inside artery walls (atherosclerosis). (harvard.edu)
  • Coronary artery disease (CAD) is narrowing of the arteries to your heart caused by a buildup of plaque. (drugs.com)
  • This often preventable disease causes the dangerous thickening and narrowing of the coronary arteries-the vessels that bring blood to the heart-which disrupts the flow of oxygen and nutrients to the heart, causing serious problems. (hopkinsmedicine.org)
  • The narrowing of coronary arteries reduces the supply of oxygen-rich blood flowing to the heart, which becomes more pronounced during strenuous activities during which the heart beats faster. (wikipedia.org)
  • Illustration depicting atherosclerosis in a coronary artery. (wikipedia.org)
  • Coronary artery disease is usually caused by atherosclerosis. (encyclopedia.com)
  • Coronary heart disease , also called coronary artery disease or ischemic heart disease , disease characterized by an inadequate supply of oxygen-rich blood to the heart muscle (myocardium) because of narrowing or blocking of a coronary artery by fatty plaques ( see atherosclerosis ). (britannica.com)
  • Coronary heart disease is generally due to the buildup of plaques in the arterial walls, a process known as atherosclerosis. (healthcentral.com)
  • Coronary artery disease results from atherosclerosis, a buildup of fatty deposits and plaque in the lining of a coronary artery, which narrows the artery and causes a decrease in blood flow to the heart muscle. (emoryhealthcare.org)
  • Coronary heart disease or coronary artery disease ( CAD ) is atherosclerosis ( plaque in artery walls) of the inner lining of the blood vessels that supply blood to the heart . (rxlist.com)
  • Atherosclerosis and inflammation are the main cause of coronary artery disease. (healthgrades.com)
  • Coronary artery disease is a pathological condition in which a coronary artery is narrowed or blocked, usually as a result of atherosclerosis. (nature.com)
  • This Review discusses the clinical features of cardiovascular disease in patients with HIV infection, including the mechanisms underlying HIV-associated atherosclerosis and approaches to reduce the cardiovascular risk. (nature.com)
  • Anger proneness predicts coronary heart disease risk: prospective analysis from the Atherosclerosis Risk in Communities (ARIC) study. (chiroweb.com)
  • Coronary heart disease results from atherosclerosis, or plaque buildup in the blood. (howstuffworks.com)
  • The U.S. Food and Drug Administration today approved the first fully absorbable stent to treat coronary artery disease. (fda.gov)
  • Doctors often treat coronary artery disease with a procedure called angioplasty to widen the artery using a metal stent. (fda.gov)
  • William J. Brown, vice president of business development at Wasatch Photonics, said the outcome of developing the technology will be the availability of a new tool to identify and treat coronary artery disease. (purdue.edu)
  • Many medications may be used to treat coronary artery disease including aspirin and statins that help lower cholesterol and prevent plaque formation. (montgomeryadvertiser.com)
  • Another procedure performed to treat coronary artery disease is a surgery called Coronary Artery Bypass Grafting A healthy blood vessel (called a graft) is inserted into the aorta and attached to the blocked coronary artery just distal to the blockage and restores normal blood flow to the heart. (montgomeryadvertiser.com)
  • Anticoagulants are not typically used to treat coronary artery disease. (healthlinkbc.ca)
  • [10] Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. (wikipedia.org)
  • Coronary angioplasty is also known as percutaneous coronary intervention (PCI), percutaneous transluminal coronary angioplasty (PTCA), or balloon angioplasty. (www.nhs.uk)
  • This is also called percutaneous coronary revascularization. (news-medical.net)
  • However, even though coronary intervention through both percutaneous coronary intervention and coronary artery bypass grafting have greatly improved outcomes in the setting of acute coronary syndrome, the same has not been systematically true for stable ischemic heart disease. (springer.com)
  • ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention-summary article. (springer.com)
  • A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (ACC/AHA/SCAI writing committee to update the 2001 guidelines for percutaneous coronary intervention). (springer.com)
  • Percutaneous coronary intervention versus conservativetherapy in nonacute coronary artery disease: a meta analysis. (springer.com)
  • The drug-eluting stents (DESs) are currently used in the majority of percutaneous coronary intervention (PCI) procedures. (centerwatch.com)
  • In the COACT trial, a strategy of immediate coronary angiography and percutaneous coronary intervention did not improve outcomes following successful resuscitation after out-of-hospital cardiac arrest in the absence of ST-segment elevation myocardial infarction. (nature.com)
  • Explain that SYNTAX scores, which are typically used to triage patients to percutaneous or surgical coronary intervention, may also be predictive of future events in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention (PCI). (medpagetoday.com)
  • Complex Percutaneous Coronary Interventions The section welcomes a variety of topics and article types. (frontiersin.org)
  • Coronary artery disease ( CAD ), also known as ischemic heart disease ( IHD ), [13] refers to a group of diseases which includes stable angina , unstable angina , myocardial infarction , and sudden cardiac death . (wikipedia.org)
  • It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. (ebi.ac.uk)
  • Coronary heart disease is a cardiovascular disease in which there is a failure of coronary circulation to supply adequate circulation to cardiac muscle and surrounding tissue. (ebi.ac.uk)
  • Coronary artery disease (CAD) is the most common type of heart disease in the United States. (cdc.gov)
  • It is sometimes called coronary heart disease or ischemic heart disease. (cdc.gov)
  • Learn the facts about heart disease , including coronary artery disease, the most common type of heart disease. (cdc.gov)
  • A family history of heart disease also increases your risk for CAD, especially a family history of having heart disease at an early age (50 or younger). (cdc.gov)
  • If you're at high risk for heart disease or already have symptoms, your doctor can use several tests to diagnose CAD. (cdc.gov)
  • Coronary heart disease (CHD) is a major cause of death both in the UK and worldwide. (www.nhs.uk)
  • CHD is sometimes called ischaemic heart disease. (www.nhs.uk)
  • Coronary heart disease cannot be cured but treatment can help manage the symptoms and reduce the chances of problems, such as heart attacks. (www.nhs.uk)
  • To learn what you can do, see Living With Heart Disease . (webmd.com)
  • When you have heart disease , you learn to eat better for the rest of your life. (webmd.com)
  • If your heart disease is advanced, it may shorten your life. (webmd.com)
  • Coronary artery disease, also called coronary heart disease or heart disease , is the leading cause of death for both men and women in the United States . (encyclopedia.com)
  • According to the American Heart Association, deaths from coronary artery disease have declined some since about 1990, but more than 40,000 people still died from the disease in 2000. (encyclopedia.com)
  • Coronary heart disease is a narrowing of the small blood vessels that supply blood and oxygen to the heart. (medlineplus.gov)
  • Coronary heart disease (CHD) is also called coronary artery disease. (medlineplus.gov)
  • A risk factor for heart disease is something that increases your chance of getting it. (medlineplus.gov)
  • You cannot change some risk factors for heart disease, but you can change others. (medlineplus.gov)
  • This is more often true in the early stages of heart disease. (medlineplus.gov)
  • The most commonly used blood pressure target for people with heart disease is less than 130/80, but your provider may recommend a different blood pressure target. (medlineplus.gov)
  • Take these steps to help prevent heart disease. (medlineplus.gov)
  • If you have heart disease, talk with your provider about starting an exercise routine . (medlineplus.gov)
  • Even if you already have heart disease, taking these steps will help protect your heart and prevent further damage. (medlineplus.gov)
  • Treatment for coronary heart disease (CHD) can help manage the symptoms and reduce the risk of further problems. (www.nhs.uk)
  • Other lifestyle changes, such as eating more healthily and doing regular exercise, will also reduce your future risk of heart disease. (www.nhs.uk)
  • examples include high blood pressure , elevated blood cholesterol levels, smoking , obesity , diabetes , unhealthy diet, and family history of early coronary heart disease (i.e., diagnosed in middle age). (britannica.com)
  • It's the most common type of heart disease. (webmd.com)
  • It is the " most common type of heart disease in the United States," where it accounts for more than 370,000 deaths every year. (medicalnewstoday.com)
  • This is a type of chest pain linked to heart disease . (medicalnewstoday.com)
  • Coronary artery disease (CAD) is the most common form of heart disease in the U.S. It's also the leading cause of death. (familydoctor.org)
  • Coronary artery disease (CAD) , also called coronary heart disease, is the most common type of heart disease . (healthline.com)
  • In the United States, heart disease is the leading cause of death, with CAD being the most common type of heart disease. (healthline.com)
  • Heart disease is one type of cardiovascular disease. (healthline.com)
  • There are rare causes of damage or blockage to a coronary artery that can also limit blood flow to the heart. (healthline.com)
  • In the event of a heart attack, your heart muscle will start to die within the territory downstream from the blocked coronary artery. (healthline.com)
  • Coronary heart disease (CHD)-also sometimes called coronary artery disease-is the most common form of cardiovascular disease, a group of disorders that involve the heart and blood vessels. (healthcentral.com)
  • Such symptoms should not be ignored, especially in people at risk of heart disease by virtue of strong family history, habitual use of certain drugs (such as cocaine), and age (all people over the age of 40). (healthcentral.com)
  • The clots may block the narrowed coronary artery completely and cause a heart attack. (healthcentral.com)
  • Who Gets Coronary Heart Disease? (healthcentral.com)
  • Cathleen D. Gillespie, MS, Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, CDC. (cdc.gov)
  • Heart disease and stroke are the first and fourth leading causes of death, respectively in the United States ( 1,2 ). (cdc.gov)
  • In 2008, heart disease and stroke were responsible for nearly a third of all deaths in the United States (30.4%), killing more than three-quarters of a million people that year ( 1 ). (cdc.gov)
  • Coronary heart disease (CHD) is the cause of more than two-thirds of all heart disease-related deaths ( 1,2 ). (cdc.gov)
  • This heart disease and stroke analysis and discussion that follows is part of the second CDC Health Disparities and Inequalities Report (2013 CHDIR) ( 6 ). (cdc.gov)
  • The purposes of the coronary heart disease and stroke mortality report are to discuss and raise awareness of differences in the characteristics of persons dying from coronary heart disease and stroke, and to prompt actions to reduce disparities. (cdc.gov)
  • CDC estimated the number of deaths and the rate of death per 100,000 population for which coronary heart disease or stroke were the underlying cause of death (ICD-10 codes I20-I25 for CHD, I60-I69 for stroke), and 95% confidence intervals were calculated based on a Poisson distribution, consistent with NCHS methodology ( 1 ). (cdc.gov)
  • When a coronary artery suddenly becomes blocked and blood flow to an area of heart muscle stops, it is called a heart attack. (emoryhealthcare.org)
  • It may be that these new cardiovascular risk factors are responsible for accelerating coronary heart disease in patients with RA. (nih.gov)
  • Coronary heart disease develops over time. (familydoctor.org)
  • How is coronary heart disease diagnosed? (familydoctor.org)
  • Can coronary heart disease be prevented or avoided? (familydoctor.org)
  • The classic epidemiologic studies by Bang and Dyerberg carried out among Greenland Eskimos suggested that a high intake of N-3 polyunsaturated fatty acids through a high intake of marine foods is associated with a low mortality from coronary heart disease (1,2). (springer.com)
  • Also the low mortality from coronary heart disease and the high fish intake in Japan is taken as evidence for the inverse relation between N-3 polyunsaturated fatty acids and coronary heart disease (3). (springer.com)
  • It can, however, not be ruled out that confounding factors may explain the relation between fish intake and coronary heart disease. (springer.com)
  • In this paper the relation between fish consumption and coronary heart disease in between and within population studies will be reviewed. (springer.com)
  • International differences in coronary heart disease mortality and consumption of fish and other foodstuffs. (springer.com)
  • Epidemiological studies related to coronary heart disease: characteristics of men aged 40-59 in seven countries. (springer.com)
  • Keys A.. Coronary heart disease in seven countries. (springer.com)
  • Keys A.. Seven countries: A multivariate analysis of death and coronary heart disease. (springer.com)
  • The inverse relation between fish consumption and 20-year mortality from coronary heart disease. (springer.com)
  • CAD, which typically builds up over decades, is the most common form of heart disease and is the leading cause of heart disease-related death worldwide. (bidmc.org)
  • Family history of heart disease: your risk increases if your father or brother was diagnosed with CAD before age 55, or your mother was diagnosed before age 65. (bidmc.org)
  • Dr. Tom Nguyen, cardiothoracic and vascular surgeon with Memorial Hermann Heart & Vascular Institute-Texas Medical Center , discusses heart attacks and coronary artery bypass surgery. (memorialhermann.org)
  • Coronary heart disease can't be cured. (nidirect.gov.uk)
  • Heart disease and stroke statistics-2007 update. (springer.com)
  • Male pattern baldness is linked to a higher risk of coronary heart disease, but only if it is on the top/crown of a man's head. (medicalnewstoday.com)
  • The investigators searched the Medline and Cochrane Library databases for studies published on male pattern baldness and coronary heart disease . (medicalnewstoday.com)
  • The team found that balding men had a 70% higher risk of having heart disease, while those in younger age groups had a 84% elevated chance . (medicalnewstoday.com)
  • Coronary heart disease is responsible for about 370,000 deaths each year in the U.S., according to the National Heart, Lung, and Blood Institute. (fda.gov)
  • This can cause chest pain (angina), shortness of breath, fatigue or other heart disease symptoms. (fda.gov)
  • Coronary artery disease (CAD) is the disease of blood vessels in the heart. (centerwatch.com)
  • TAKEDA EXAMINE trial patients for who have Type II diabetes & ACS coronary artery disease, post angiogram or heart attack. (centerwatch.com)
  • The primary purpose of this study is to evaluate whether treatment with rivaroxaban and aspirin or rivaroxaban alone is better than aspirin alone in prevention of heart attacks, stroke or cardiovascular death in patients with coronary or peripheral artery disease. (centerwatch.com)
  • Epidemiologic evidence has linked trans fatty acids (TFAs) in the diet to coronary heart disease in human populations. (nih.gov)
  • Although it is known that TFAs increase low-density lipoprotein (LDL) cholesterol levels and decrease high-density lipoprotein (HDL) cholesterol levels (markers of coronary heart disease), there is little known about the mechanisms by which TFAs actually function at the cellular level. (nih.gov)
  • Coronary heart disease is a common form of heart disease and is a major cause of illness and death . (rxlist.com)
  • Coronary heart disease begins when hard cholesterol substances (plaques) are deposited within a coronary artery. (rxlist.com)
  • What is the purpose of screening tests for coronary heart disease? (rxlist.com)
  • In many individuals, the first symptom of coronary heart disease is heart attack or sudden death, with no preceding chest pain as a warning. (rxlist.com)
  • For this reason, doctors perform screening tests to detect signs of coronary heart disease before serious medical events occur so the tests are designed to detect plaque (Figure 1) before a coronary artery becomes completely blocked (Figure 2). (rxlist.com)
  • Screening tests are of particular importance for people with risk factors for coronary heart disease. (rxlist.com)
  • These risk factors include a family history of coronary heart disease at relatively young ages, an abnormal serum cholesterol profile, cigarette smoking , elevated blood pressure ( hypertension ), and diabetes mellitus . (rxlist.com)
  • What are common initial screening tests for coronary heart disease? (rxlist.com)
  • An electrocardiogram (EKG, ECC) usually is the first and most simple test used to look for any coronary heart disease signs. (rxlist.com)
  • Unless the person is actively having a heart attack, which often is seen as an electrical change in the heart rhythm (ST segment elevation), the EKG may show electrical changes such as ST depressions or Q waves that suggest the patient has coronary heart disease or coronary heart disease with signs of a previous heart attack. (rxlist.com)
  • Initial screening for coronary heart disease commonly involves stressing the heart under controlled conditions. (rxlist.com)
  • If a coronary arterial blockage results in decreased blood flow to a part of the heart during exercise, certain changes (for example, ST segment depressions) may be observed in the EKG, as well as in the response of the heart rate and blood pressure. (rxlist.com)
  • The accuracy of the ECST in predicting significant coronary heart disease is variable, depending in part on the "pre-test likelihood" of coronary heart disease (also known as Bayes' theorem ). (rxlist.com)
  • In a person at high risk for coronary heart disease (for example, advanced age, multiple coronary risk factors), an abnormal ECST is very predictive of the presence of coronary heart disease (over 90% accurate). (rxlist.com)
  • High blood pressure, menopause, and obesity - these are some ​​modifiable risk factors for coronary heart disease. (reference.com)
  • Coronary artery disease (CAD) is the most common form of heart disease. (healthgrades.com)
  • Coronary heart disease and ischemic heart disease are other names for CAD. (healthgrades.com)
  • As the disease continues, the heart struggles to work without enough oxygen. (healthgrades.com)
  • Heart attack happens when blood flow through a coronary artery becomes completely blocked. (healthgrades.com)
  • Also called coronary heart disease (CHD), CAD is the most common form of heart disease and affects approximately 16.5 million Americans over the age of 20. (healthline.com)
  • Men have a higher risk of developing heart disease than premenopausal women. (healthline.com)
  • Doctors trained in heart disease (cardiologists) in the Coronary Artery Disease Clinic at Mayo Clinic's campus in Minnesota have extensive experience and expertise in diagnosing and treating the most challenging forms of coronary artery disease and other heart conditions. (mayoclinic.org)
  • The staff in the Coronary Artery Disease Clinic has experience diagnosing and treating high-risk and complex forms of coronary artery disease, chest pain (intractable angina), and valvular heart disease . (mayoclinic.org)
  • Coronary heart disease (CHD) or coronary artery disease occurs when a coronary artery clogs and narrows because of a buildup of plaque. (heartfoundation.org.au)
  • There is no single cause for coronary heart disease (also known as coronary artery disease). (heartfoundation.org.au)
  • Many people don't know they have coronary heart disease until they have angina or a heart attack. (heartfoundation.org.au)
  • Heart disease is the leading cause of death of Australians. (heartfoundation.org.au)
  • Yet many Australians don't know that they have coronary heart disease until they have a heart attack - which can be life-threatening - or angina. (heartfoundation.org.au)
  • Is coronary heart disease the same as cardiovascular disease? (heartfoundation.org.au)
  • Cardiovascular disease is any disease of the heart and/or blood vessels. (heartfoundation.org.au)
  • What are the risk factors for coronary heart disease? (heartfoundation.org.au)
  • To diagnose CHD, your doctor will review your symptoms, ask about a family history of heart disease and conduct a physical examination. (heartfoundation.org.au)
  • Coronary heart disease is reduced by lowering plasma homocystine levels with a diet supplement of folic acid alone or in combination with cyanocobalamin. (medindia.net)
  • Dr.Tice from the University of California at San Francisco and colleagues used the Coronary Heart Disease Policy Model to assess the cost effectiveness of lowering levels of homocystine through grains fortified with folic acid and with cyanocobalamin and folic acid among participants in the third National Health and Nutrition Examination Survey. (medindia.net)
  • Heart disease can be of many types depending upon whether they involve the heart muscles or artery walls or heart beats. (medindia.net)
  • Bad lifestyle choices contribute to heart disease. (medindia.net)
  • Whether or not you have had a heart attack, there are many things you can do to slow coronary artery disease and reduce your risk of future problems. (rexhealth.com)
  • A heart attack is sometimes the first sign of coronary artery disease. (rexhealth.com)
  • and having heart disease in your family. (rexhealth.com)
  • If your doctor thinks that you have coronary artery disease, you may have tests to check how well your heart is working. (rexhealth.com)
  • You may also have a coronary angiogram to check blood flow to the heart. (rexhealth.com)
  • This disease affects an estimated 16 million Americans and is a primary cause of heart attacks and strokes. (purdue.edu)
  • Take the Heart Disease Quiz First! (medicinenet.com)
  • Stressed induced coronary heart disease is just common in men as it is in women. (montgomeryadvertiser.com)
  • Death by heart disease is the most common death in the United States. (montgomeryadvertiser.com)
  • Heart disease affects an estimated 15 million Americans and is the leading cause of death for women and men around the world. (montgomeryadvertiser.com)
  • In the United States, coronary artery disease accounts for approximately 370,000 deaths each year, according to the National Heart, Lung and Blood Institute. (montgomeryadvertiser.com)
  • Some of the tests or procedures that may be done include a blood test, electrocardiogram, ultrasound of heart, stress test, CT scan or Coronary angiogram. (montgomeryadvertiser.com)
  • Around one in six men and one in nine women die from heart disease. (prezi.com)
  • There are nearly 2.7 million people living with heart disease in the UK. (prezi.com)
  • Death rates from heart disease are highest in Scotland and northern England and lowest in southern England. (prezi.com)
  • But what do YOU know about heart disease? (prezi.com)
  • We asked people around our college some basic questions about heart disease, to find out what people really know. (prezi.com)
  • The answers proved that people don't know nearly enough about heart disease. (prezi.com)
  • THE ANSWERS What are the causes of heart disease? (prezi.com)
  • If you knew how would you take the measures to prevent heart disease? (prezi.com)
  • The biggest killer of people in the UK is heart disease How do you prevent heart disease? (prezi.com)
  • Would you be surprised if i told you heart disease was the biggest killer? (prezi.com)
  • To prevent heart disease there are a few things you can do. (prezi.com)
  • What do you think heart disease is? (prezi.com)
  • The thickness of the coronary artery wall as measured by MRI is an independent marker for heart disease in women, according to a study published online, April 25, in the journal Radiology: Cardiothoracic Imaging. (prweb.com)
  • For instance, there is evidence that the commonly used Framingham Risk Score, which provides estimates of cardiovascular disease risk based on age, sex and other factors, underestimates the chance of heart attacks and other cardiovascular events in asymptomatic women. (prweb.com)
  • Over a period of years, Dr. Abd-Elmoniem and colleagues developed and refined an MRI technique that adjusts for the motions of breathing and the beating heart to directly visualize coronary wall thickness. (prweb.com)
  • Do Daily PTSD-Induced Emotional Triggers Increase Risk for Coronary Heart Disease? (plos.org)
  • They are at increased risk for developing type 2 diabetes , which is an important risk factor for heart disease and stroke . (heart.org)
  • Acute coronary syndrome is an umbrella term for when blood supplied to the heart muscle is decreased or blocked, leading to a heart attack . (heart.org)
  • The elderly and people with existing heart diseases may be at higher risk from short-term exposure (hours or weeks). (heart.org)
  • Unfortunately for Millie, she had a family history of heart disease. (medtronic.com)
  • We took 200 patients," says Dr. Puskas, "who had every sort of degree of heart disease: coronary blockages, reduced ventricular function, or heart failure, and we randomized them to have their operations with or without the heart-lung machine, that is to say stopped heart surgery or beating heart surgery. (medtronic.com)
  • Coronary heart disease is the leading cause of death in the United States, but it can be prevented by making good lifestyle choices. (howstuffworks.com)
  • Learn about the causes and symptoms of coronary heart disease as well as methods for treatment and prevention. (howstuffworks.com)
  • Born in 1948, and still going strong, the Framingham Heart Study has told us just about everything we know about how people get heart disease and strokes. (howstuffworks.com)
  • Angina and heart attack are often among the symptoms of coronary heart disease. (howstuffworks.com)
  • Whereas men experience crushing chest pain as an obvious sign of coronary heart disease, women often have no symptoms. (howstuffworks.com)
  • Coronary heart disease, or CHD, can effect the body in many ways. (howstuffworks.com)
  • Coronary artery disease is the most common type of heart disease, according to the Centers for Disease Control and Prevention. (eurekalert.org)
  • CT is particularly useful for high-resolution images of the coronary anatomy, while cardiac MRI can provide information on blood supply to the heart muscle without exposing patients to ionizing radiation. (eurekalert.org)
  • Also searched for Myocardial ischaemia , Coronary artery diseases , Heart and more. (clinicaltrials.gov)
  • Genetic and environmental determinants of plasma nitrogen oxides and risk of ischemic heart disease," Hypertension , vol. 38, no. 5, pp. 1054-1061, 2001. (hindawi.com)
  • Angiotensin-converting enzyme gene polymorphism in coronary artery disease in North India," Indian Heart Journal , vol. 56, no. 1, pp. 44-46, 2004. (hindawi.com)
  • Association of endothelial constitutive nitric oxide synthase gene polymorphism with acute coronary syndrome in Koreans," Heart , vol. 90, no. 3, pp. 282-285, 2004. (hindawi.com)
  • Even if you have smoked for many years, if you quit, you can cut your chances of having a coronary heart disease event (such as a heart attack) in half within a year or two of quitting. (healthcentral.com)
  • Whether you have prehypertension or hypertension, lowering your blood pressure not only will reduce your likelihood of developing coronary artery disease but also can lower your risk of having a heart attack or stroke, or developing heart failure. (healthcentral.com)
  • The Systolic Blood Pressure Intervention Trial (SPRINT) found that maintaining systolic blood pressure in the 120 to 125 mm Hg range was associated with significantly fewer atherosclerotic cardiovascular disease events (such as heart attack or stroke) than keeping it in the 135 to 140 mm Hg range. (healthcentral.com)
  • High blood levels of total cholesterol, LDL cholesterol, and triglycerides and low levels of HDL cholesterol increase your risk of coronary heart disease. (healthcentral.com)
  • Although the SYNTAX score was not conceived as a method to predict outcomes related to anatomic characteristics, some reports have demonstrated that it may be an effective tool for predicting the risk of major ischemic events in patients undergoing PCI with stable ischemic heart disease and multivessel or left main disease, Palmerini and colleagues wrote. (medpagetoday.com)
  • Thus, the association between auricular signals and coronary heart disease (CHD) should be further investigated. (hindawi.com)
  • The results showed that the presence of an ear lobe crease (ELC) was significantly associated with coronary heart disease. (hindawi.com)
  • The association between the presence of an ear lobe crease (ELC) and coronary heart disease (CHD) was first reported by Frank [ 4 ] who identified diagonal creases on the ear lobes that run either unilaterally or bilaterally from the lower probe of the external auditory meatus diagonally backwards to the edge of the lobe [ 5 ]. (hindawi.com)
  • Despite the decline in age-standardized death rates of CHD patients in the last two decades, deaths due to CHD accounts for 70% of the mortality rate of heart disease [ 15 ]. (hindawi.com)
  • Although the increased risk of premature heart disease in type 1 diabetes has been recognized for some time, the underlying pathogenesis is still poorly understood. (diabetesjournals.org)
  • However, despite recent evidence from the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study that prior intensive glycemic control reduces cardiovascular disease (CVD), the epidemiologic association between glycemia and coronary heart disease (CHD) is surprisingly weak. (diabetesjournals.org)
  • The Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR) also reported a standardized mortality ratio (SMR) from ischemic heart disease of 9.1 (for men) and 13.5 (for women) for those with a diabetes diagnosis before 30 years of age ( 5 ). (diabetesjournals.org)
  • In those aged 20-29 years, SMRs for ischemic heart disease mortality of 11.8 in men and 44.8 in women were reported, while for those aged 30-39 years, SMRs were 8.0 and 41.6, respectively. (diabetesjournals.org)
  • Over time, coronary artery disease can also lead to heart failure and arrhythmias. (heart.org)
  • Risk factors for heart disease are conditions or habits that make it more likely that you will get heart disease. (heartandstroke.ca)
  • Age - the older you are, the higher your risk of heart disease. (heartandstroke.ca)
  • Sex - Your risk of heart disease and stroke increases after menopause. (heartandstroke.ca)
  • Family history - if you have a close relative who has experienced heart disease at an early age, you are at an increased risk. (heartandstroke.ca)
  • They are at greater risk of heart disease than the general population. (heartandstroke.ca)
  • South Asian and African heritage - people of African or South Asian heritage also have a higher risk of heart disease. (heartandstroke.ca)
  • This is because they are more likely to have high blood pressure (hypertension), diabetes or other risk factors for heart disease at a younger age. (heartandstroke.ca)
  • You can lower your risk of coronary artery disease, heart disease and stroke by knowing and controlling your blood pressure, diabetes and blood cholesterol. (heartandstroke.ca)
  • Eat a healthy balanced diet - there are some specific diets you can follow that have been proven to reduce the risk of heart disease. (heartandstroke.ca)
  • To find useful services to help you on your journey with heart disease, see our services and resources listing . (heartandstroke.ca)
  • Every minute, an American dies of coronary heart disease. (scribd.com)
  • Coronary heart disease afflicts over 13 million Americans. (scribd.com)
  • The estimated cost for cardiovascular disease in 1994 by the American Heart Association is 128 billion dollars. (scribd.com)
  • CAD is the most common form of heart disease, affecting around 17 million Americans. (intermountainhealthcare.org)
  • The first sign of the disease is often chest pain (angina) or a heart attack. (intermountainhealthcare.org)
  • Despite these grim facts, most people can live full and rewarding lives with heart disease. (intermountainhealthcare.org)
  • Preventing coronary artery disease takes proper screening and a heart-healthy lifestyle. (intermountainhealthcare.org)
  • The results of a study involving 12,986 men and women (45-64 years old at baseline) provide evidence that anger may predict coronary heart disease (CHD). (chiroweb.com)
  • It might mean the difference in staying healthy instead of suffering from heart disease. (chiroweb.com)
  • It is also known as coronary heart disease (CHD), or simply, heart disease. (hubpages.com)
  • The ideal blood cholesterol level for you depends on your age, gender, and history of heart disease, but for most people with coronary artery disease, the target LDL cholesterol level is 100 mg/dL or below, and the target HDL cholesterol level is above 40 mg/dL for men, and above 50 mg/dL for women. (hubpages.com)
  • Coronary plaque buildup may progress more quickly in patients with diabetes compared with those without diabetes, according to research results published in Clinical Cardiology and presented at the 3rd Annual Heart in Diabetes Conference, held July 12 to 14, 2019, in Philadelphia, Pennsylvania. (hubpages.com)
  • Myocardial infarctions (heart attacks), arrhythmia, heart failure and stroke are among several serious complications of coronary artery disease. (hubpages.com)
  • Coronary heart disease is a disease of the vessels that supply the heart with blood and oxygen. (howstuffworks.com)
  • Coronary heart disease is a type of cardiovascular disease. (howstuffworks.com)
  • Coronary heart disease is not a part of growing older that can be avoided, nor is it something that can be ignored until you're over 65. (howstuffworks.com)
  • Start here to learn what you need to know about coronary heart disease. (howstuffworks.com)
  • Doctors take several factors into account to diagnose coronary heart disease. (howstuffworks.com)
  • Extensive research has gone into determining the risk factors for heart disease. (howstuffworks.com)
  • Managing coronary heart disease can encompass a variety of treatments, from medication to surgery. (howstuffworks.com)
  • People who smoke expose their family members to secondhand smoke , increasing the risk of heart disease in their family members. (rexhealth.com)
  • The recent untimely deaths of Internet stars Auntie Fee (pictured above) and Q Worldstar serve as reminders that heart disease is the number 1 killer of men and women in the U.S. (sandrarose.com)
  • For many people the first sign or symptom of heart disease is death. (sandrarose.com)
  • This is why heart disease is called the silent killer. (sandrarose.com)
  • Former President George Bush underwent a procedure earlier today to place a coronary stent in a blocked coronary artery in his heart. (sandrarose.com)
  • The coronary stent will keep the artery open to allow adequate blood flow in his heart. (sandrarose.com)
  • Plaque builds up within the coronary artery walls until the flow of oxygen-rich blood to the heart muscle is limited. (reportlinker.com)
  • In chronic ischemia, the coronary artery narrows over time, limiting the blood flow to part of the heart muscle, while acute ischemia occurs due to a sudden rupture of plaque and formation of a blood clot. (reportlinker.com)
  • The term 'heart disease,' also known as cardiovascular disease, covers a lot of ground. (harvard.edu)
  • No wider than a strand of spaghetti, each coronary artery deliver bloods to hard-working heart muscle cells. (harvard.edu)
  • When a coronary artery becomes clogged with plaque, it can't always deliver enough blood to the heart muscle cells it is supposed to supply. (harvard.edu)
  • Coronary artery disease can also be the root cause of a heart attack, or lead to the chronic condition known as heart failure. (harvard.edu)
  • Background:To study the prevalence of coronary artery disease (CAD) in patients undergoing valve surgery for rheumatic and non-rheumatic valvular heart disease. (doaj.org)
  • Methods: In this cross sectional study, 233 patients planned for valvular heart surgery and aged 40 years or more were subjected to preoperative coronary angiogram. (doaj.org)
  • Logistic regression analysis was used to study predictive factors for CAD in valvular heart disease. (doaj.org)
  • 56% of patients had RHD, while 21% had degenerative valvular heart disease. (doaj.org)
  • The overall prevalence of CAD was found to be 31.3% in valvular heart disease (VHD). (doaj.org)
  • Of patients in the study with obstructive heart disease, 30,160 were being treated with statins, another 2,042 had been prescribed only nonstatin lipid-lowering medications, and 6,441 got both. (medpagetoday.com)
  • Are you sure you want to remove Triglyceride, high density lipoprotein, and coronary heart disease from your list? (openlibrary.org)
  • This is a program run by specialists who will help you safely strengthen your heart and reduce the risk of more heart disease. (drugs.com)
  • Coronary artery disease (also called coronary heart disease ) is the number-one killer of both men and women in the United States, and it's the most common type of heart disease. (hopkinsmedicine.org)
  • Coronary artery disease develops slowly, usually over decades, so the good news is that we have a huge window of opportunity for prevention, through a good lifestyle and healthy habits," says Seth Martin, M.D., M.H.S. , of the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease. (hopkinsmedicine.org)
  • Ideally, prevention habits start early, but they remain important all through life," Bill McEvoy , MBBCh, of the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease says. (hopkinsmedicine.org)
  • This test may be considered in persons without known coronary heart disease in whom the decision to treat with a statin and aspirin is unclear. (hopkinsmedicine.org)
  • Coronary heart disease, susceptibility to, 8 is a protein that in humans is encoded by the CHDS8 gene. (wikipedia.org)
  • What are the symptoms of coronary artery disease? (cdc.gov)
  • About 13 million Americans have active symptoms of coronary artery disease . (encyclopedia.com)
  • But, you can have the disease and not have any symptoms. (medlineplus.gov)
  • Treatment depends on your symptoms and how severe the disease is. (medlineplus.gov)
  • A lack of blood flow can cause chest pain, shortness of breath, and other symptoms of cardiac disease. (healthline.com)
  • Read more about how to identify the symptoms of coronary artery disease here. (healthline.com)
  • In the early stages of the disease, there are generally no symptoms. (healthcentral.com)
  • Common symptoms of coronary artery disease include shortness of breath and angina (pain or a feeling of increased pressure in the chest). (emoryhealthcare.org)
  • Coronary artery disease can progress for years, even decades, without symptoms. (bidmc.org)
  • Coronary artery disease is often referred to as the silent killer because symptoms can go undetected. (montgomeryadvertiser.com)
  • Imaging tools like coronary computed tomography angiography (CCTA) tend to be used in patients with symptoms or more advanced cardiovascular disease, but are not recommended for liberal use in risk assessment among the general population with no cardiac symptoms. (prweb.com)
  • In this article you will learn more about symptoms, risks and prevention of this disease. (howstuffworks.com)
  • Learn about coronary artery disease causes, risk factors, and symptoms. (intermountainhealthcare.org)
  • Nitrates, beta blockers, calcium channel blockers, aspirin, or cholesterol-lowering drugs (statins) are used to slow the disease progress or ease symptoms. (hubpages.com)
  • Because coronary artery disease develops over time, the symptoms depend on the stage of illness. (hopkinsmedicine.org)
  • Nitrates can be used to treat angina, a common complication of coronary artery disease. (news-medical.net)
  • If you have a stable pattern of angina, other tests may be done to determine the severity of your disease. (bidmc.org)
  • Eleven-year survival in the veterans administration randomized trial of coronary bypass surgery for stable angina. (springer.com)
  • Eighteen-year survival in the veterans affairs cooperative study of coronary artery bypasss surgery for stable angina. (springer.com)
  • Coronary angioplasty versus medical therapy for angina: the second Randomised Intervention Treatment of Angina (RITA-2) trial. (springer.com)
  • Acute Coronary Syndrome covers the spectrum of clinical conditions ranging from unstable angina to non-ST elevation myocardial infarction and ST elevation myocardial infarction. (wiley.com)
  • Without enough blood, coronary artery disease can lead to angina (chest pain). (hopkinsmedicine.org)
  • A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others. (wikipedia.org)
  • In addition to diet, exercise, medication therapy and coronary artery bypass graft (CABG) surgery there are a number of minimally invasive procedures that can restore blood flow through a blocked coronary artery. (emoryhealthcare.org)
  • Bernie Sanders, independent candidate of Vermont, was rushed into surgery for a blocked coronary artery after he experienced chest pains during a campaign event on Tuesday. (sandrarose.com)
  • The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin compared with placebo, in addition to standard of care, in patients with type II diabetes mellitus and acute coronary syndrome. (centerwatch.com)
  • Acute coronary syndrome has a male predominance. (reportlinker.com)
  • Coronary artery bypass surgery (also known as coronary artery bypass grafting) or angioplasty may be necessary if medications and diet and lifestyle changes, such as frequent exercise and cessation of smoking, are not effective. (britannica.com)
  • One coronary intervention is coronary angioplasty and stent placement. (news-medical.net)
  • Meta-analysis of randomised trials comparing coronary angioplasty with bypass surgery. (springer.com)
  • Burgeoning dilemmas in the management of diabetes and cardiovascular disease: rationale for the bypass angioplasty revascularization investigation 2 diabetes (BARI 2D) trial. (springer.com)
  • The FDA's approval of the Absorb GT1 BVS offers a new treatment option for individuals who are candidates for angioplasty, but would prefer an absorbable device rather than a permanent metallic coronary stent," said Bram Zuckerman, M.D., director of the division of cardiovascular devices at the FDA's Center for Devices and Radiological Health. (fda.gov)
  • Learn about treatment options for coronary artery disease, including angioplasty, stent placement, and coronary artery bypass surgery (CABG). (intermountainhealthcare.org)
  • Treatment may also require surgical intervention, such as with angioplasty, stent replacement, coronary artery bypass graft surgery (CABG) or off-pump coronary artery bypass surgery. (hubpages.com)
  • Coronary angiography and revascularization began in the 1960s and has evolved dramatically into a robust platform for not only diagnosis of coronary disease but also complex intervention. (springer.com)
  • The information should not be used for either diagnosis or treatment or both for any health related problem or disease. (medindia.net)
  • TECHREPORT{Silver97thefunctional, author = {Daniel L. Silver and Robert E. Mercer and Gilbert A. Hurwitz}, title = {The Functional Transfer of Knowledge for Coronary Artery Disease Diagnosis}, institution = {Comput. (psu.edu)
  • Management of Acute Coronary Syndromes is designed to provide busy clinicians with a comprehensive guide to the investigation, diagnosis and treatment of these syndromes. (wiley.com)
  • To diagnose coronary artery disease, your doctor will look at markers such as blood pressure, cholesterol profile and blood glucose (from a blood test) as well as your health history and family history, says McEvoy. (hopkinsmedicine.org)
  • Another procedure is coronary artery bypass grafting (CABG). (news-medical.net)
  • Patients with coronary artery disease (CAD) requiring coronary artery bypass grafting (CABG) are still at significant risk for postoperative major adverse cardiocerebral events (15% MACCE rate), with 3% of patients dying within 30 days of surgery. (centerwatch.com)
  • For the study, researchers retrospectively examined 2,627 patients from the ACUITY trial, which randomized patients with moderate and high-risk non-ST-segment elevation acute coronary syndromes to either PCI, coronary artery bypass graft (CABG) surgery, or medical therapy. (medpagetoday.com)
  • Identifying and treating plaque buildup and other intravascular conditions could reduce the morbidity and mortality rates from coronary artery disease," he said. (purdue.edu)
  • A single image and measurement of coronary vessel wall thickness with MRI can be used to gauge the extent of coronary plaque in asymptomatic women, who then can be appropriately referred for further exams and/or treatment," said Dr. Abd-Elmoniem. (prweb.com)
  • The cause of coronary artery disease is almost always atherosclerotic plaque-gooey cholesterol-filled deposits that form inside artery walls. (harvard.edu)
  • Comparative pathologic study.Natural history of the human coronary atherosclerotic plaque and related forms of myocardial injuries.Findings in acute coronary syndromes.Revisiting dogma related to coronary artery disease.Adrenergic stress. (routledge.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • Prevention of Coronary. (bmj.com)
  • Circulating vesicles released from platelets, erythrocytes, leukocytes, and endothelial cells contain potential valuable biological information for biomarker discovery in primary and secondary prevention of coronary artery disease. (nih.gov)
  • Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor, more frequently clopidogrel, represents the standard of care for the long-term secondary prevention of atherothrombotic events in patients with myocardial infarction (MI) or peripheral arterial disease (PAD). (centerwatch.com)
  • While further studies are needed, these results emphasize the unique nature of coronary artery disease development in women compared to men, and show that MRI could one day be a useful tool in the prevention and management of the disease in women, especially for those with intermediate risk. (prweb.com)
  • In this article learn more about the signs, causes and prevention of this disease. (howstuffworks.com)
  • But in view of the fact that the direct cause of sudden death of the disease is thrombotic occlusion of a coronary artery, aspirin might act as the effective means for prevention of sudden death due to Kawasaki disease. (aappublications.org)
  • With this, the world saw ever-increasing revascularization of coronary stenoses in patients ranging from those with asymptomatic lesions to those suffering an acute myocardial infarction. (springer.com)
  • Combining genotyping data from the Wellcome Trust Case Control Consortium study and the German Myocardial Infarction Family Study, researchers confirmed a region on chromosome 9 to be highly associated with coronary artery disease. (genomeweb.com)
  • Association of the endothelial nitric oxide synthase gene polymorphism with risk of coronary artery disease and myocardial infarction in middle-aged men," Journal of Molecular Medicine , vol. 80, no. 9, pp. 605-609, 2002. (hindawi.com)
  • High levels of anger contributed to an increased risk of CHD and other coronary events, including acute myocardial infarction (MI) and fatal CHD. (chiroweb.com)
  • For the study, Arnold and colleagues used the American College of Cardiology's Practice Innovation and Clinical Excellence (PINNACLE) database to identify 38,775 outpatients with a history of myocardial infarction or coronary revascularization. (medpagetoday.com)
  • The experienced staff in the Coronary Artery Disease Clinic diagnoses your condition, offers rapid access to cardiac catheterization and provides consultation with other specialists when needed. (mayoclinic.org)
  • The Coronary Artery Disease Clinic integrates cardiac catheterization procedures into a clinical setting. (mayoclinic.org)
  • In the Coronary Artery Disease Clinic, you may consult with doctors and be treated in Mayo's Cardiac Catheterization Laboratory soon after your consultation. (mayoclinic.org)
  • Prevalence of type 2 diabetes in Asia seems to be almost epidemic and establishment of preventive strategy against macrovascular as well as microvascular diseases are warranted because of higher cardiovascular risk in diabetic patients even without history of atherosclerotic cardiovascular diseases. (centerwatch.com)
  • The implant device is designed to continuously monitor the electrocardiogram signal and detect ST shifts that could be indicative of a blockage of a coronary artery. (centerwatch.com)
  • books.google.com - One of the leading experts in the field and a stellar cast of contributors provide all of the scientific and clinical information needed to facilitate rapid evaluation and immediate management of acute coronary syndromes using today's full range of strategies-from pharmaceutical approaches to revascularization. (google.com)
  • The technique may allow for an easier and possibly more accurate identification of patients and coronary stenoses that are likely to benefit from revascularization," Dr. von Spiczak said. (eurekalert.org)
  • Note that the lack of statin treatment was associated with no health insurance whereas factors associated with statin treatment included male sex, coexisting hypertension, and a recent coronary revascularization procedure. (medpagetoday.com)
  • Who is at risk for coronary artery disease? (healthline.com)
  • The risk for coronary artery disease is also higher if you have a family history of the disease. (healthline.com)
  • This may have allowed the team to identify barriers to prescribing for coronary artery disease(5) and to potentially adjust the intervention accordingly. (cmaj.ca)
  • Clinical observations have documented substantial differences in the extent of collateralization among patients with coronary artery disease (CAD), with some individuals demonstrating marked abundance and others showing nearly complete absence of these vessels. (ahajournals.org)
  • The purpose of this study is to evaluate possible mechanisms of aspirin resistance at a molecular level in aspirin- treated patients with coronary artery disease. (clinicaltrials.gov)
  • In addition, we will evaluate the effect of enteric coating on the pharmacologic efficacy of aspirin in patients with coronary artery disease. (clinicaltrials.gov)
  • [14] It is within the group of cardiovascular diseases of which it is the most common type. (wikipedia.org)
  • Per the World Health Organization (WHO) , cardiovascular diseases are the number one cause of death worldwide. (healthline.com)
  • It is the most common of the cardiovascular diseases. (dbpedia.org)
  • Watch Mayo Clinic cardiologists and others discuss many conditions and treatments related to cardiovascular diseases and cardiovascular surgery. (mayoclinic.org)
  • Antiretroviral therapy has transformed HIV infection into a chronic disease, and cardiovascular diseases are an important health concern in this setting. (nature.com)
  • Learn more about research in cardiovascular diseases at Mayo Clinic's Cardiovascular Research Center . (mayoclinic.org)
  • The United States Coronary Artery Disease Treatment Devices Industry 2017 Market Research Report is a professional and in-depth study on the current state of the Coronary Artery Disease Treatment Devices industry. (mynewsdesk.com)
  • The analyst estimates that in 2017, there were approximately 327.9 million prevalent cases of coronary artery disease worldwide, and forecasts that number to increase to 365.9 million prevalent cases by 2026. (reportlinker.com)
  • Risk of developing coronary artery disease increases steadily as blood cholesterol levels increase above 160 mg/dL. (encyclopedia.com)
  • They compared their approach with conventional 2D readouts in 17 patients who underwent cardiac CT and cardiac MRI due to suspected or known coronary artery disease. (eurekalert.org)
  • People with more risk factors are more likely to develop coronary artery disease. (encyclopedia.com)
  • Bald or extensively balding males had a 44% increased probability to develop coronary artery disease. (medicalnewstoday.com)
  • Two recent prospective epidemiologic studies, the Pittsburgh Epidemiology of Diabetes Complications (EDC) study ( 6 ) and Eurodiab ( 7 ), a multicenter, clinic-based study in Europe, confirmed these earlier reports and reported an incidence of total coronary events (including electrocardiogram [ECG] changes) of 16% over 10 years and 9% over 7 years, respectively, of follow-up in type 1 diabetic patients. (diabetesjournals.org)
  • Recent research indicates that infection from organisms such as chlamydia bacteria may be responsible for some cases of coronary artery disease. (encyclopedia.com)
  • It is true that the majority of chronic disease care in Canada (such as management of coronary artery disease) occurs in primary care and that there is room for improvement in how we manage these patients. (cmaj.ca)
  • 2016) [19] Journal of American Medical Association Internal Medicine Case study 60 year old male patient (1) Explored the Overdiagnosis of Coronary Artery Disease Detected by Coronary Computed Tomography Angiography. (bartleby.com)