A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
The veins and arteries of the HEART.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Narrowing or constriction of a coronary artery.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
The circulation of blood through the CORONARY VESSELS of the HEART.
Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.
An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
Elements of limited time intervals, contributing to particular results or situations.
An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Bleeding or escape of blood from a vessel.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
An isoenzyme of creatine kinase found in the CARDIAC MUSCLE.
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Compounds that bind to and block the stimulation of PURINERGIC P2Y RECEPTORS. Included under this heading are antagonists for specific P2Y receptor subtypes.
Formation and development of a thrombus or blood clot in the blood vessel.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Persistent and reproducible chest discomfort usually precipitated by a physical exertion that dissipates upon cessation of such an activity. The symptoms are manifestations of MYOCARDIAL ISCHEMIA.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Markedly reduced or absent REPERFUSION in an infarct zone following the removal of an obstruction or constriction of an artery.
The vessels carrying blood away from the heart.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Agents that prevent clotting.
The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Spasm of the large- or medium-sized coronary arteries.
Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The main artery of the thigh, a continuation of the external iliac artery.
The removal of secretions, gas or fluid from hollow or tubular organs or cavities by means of a tube and a device that acts on negative pressure.
The return of a sign, symptom, or disease after a remission.
Shock resulting from diminution of cardiac output in heart disease.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
MYOCARDIAL INFARCTION in which the anterior wall of the heart is involved. Anterior wall myocardial infarction is often caused by occlusion of the left anterior descending coronary artery. It can be categorized as anteroseptal or anterolateral wall myocardial infarction.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Conditional probability of exposure to a treatment given observed covariates.
A flexible, tubular device that is used to carry fluids into or from a blood vessel, hollow organ, or body cavity.
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.
The time required by whole blood to produce a visible clot.
The plan and delineation of prostheses in general or a specific prosthesis.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The interval of time between onset of symptoms and receiving therapy.
Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A subclass of purinergic P2Y receptors that have a preference for ADP binding and are coupled to GTP-BINDING PROTEIN ALPHA SUBUNIT, GI. The P2Y12 purinergic receptors are found in PLATELETS where they play an important role regulating PLATELET ACTIVATION.
Interfacility or intrahospital transfer of patients. Intrahospital transfer is usually to obtain a specific kind of care and interfacility transfer is usually for economic reasons as well as for the type of care provided.
Laboratory examination used to monitor and evaluate platelet function in a patient's blood.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)
Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.
Percutaneous transluminal procedure for removing atheromatous plaque from the coronary arteries. Both directional (for removing focal atheromas) and rotational (for removing concentric atheromatous plaque) atherectomy devices have been used.
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Substances used to allow enhanced visualization of tissues.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Lesions formed within the walls of ARTERIES.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
The study of the heart, its physiology, and its functions.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Obstruction of flow in biological or prosthetic vascular grafts.
Pathologic deposition of calcium salts in tissues.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
The hospital unit in which patients with acute cardiac disorders receive intensive care.
One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
Therapy with two or more separate preparations given for a combined effect.
Catheters inserted into various locations within the heart for diagnostic or therapeutic purposes.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect.
Services specifically designed, staffed, and equipped for the emergency care of patients.
Drugs used to cause dilation of the blood vessels.
Malformations of CORONARY VESSELS, either arteries or veins. Included are anomalous origins of coronary arteries; ARTERIOVENOUS FISTULA; CORONARY ANEURYSM; MYOCARDIAL BRIDGING; and others.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
Counterpulsation in which a pumping unit synchronized with the patient's electrocardiogram rapidly fills a balloon in the aorta with helium or carbon dioxide in early diastole and evacuates the balloon at the onset of systole. As the balloon inflates, it raises aortic diastolic pressure, and as it deflates, it lowers aortic systolic pressure. The result is a decrease in left ventricular work and increased myocardial and peripheral perfusion.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
The dilatation of the aortic wall behind each of the cusps of the aortic valve.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Pathological conditions involving the HEART including its structural and functional abnormalities.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
First aid or other immediate intervention for accidents or medical conditions requiring immediate care and treatment before definitive medical and surgical management can be procured.
A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
Disease having a short and relatively severe course.
VASCULAR DISEASES that are associated with DIABETES MELLITUS.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
General or unspecified injuries to the heart.
Pressure, burning, or numbness in the chest.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
The vein which drains the foot and leg.
One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Delivery of drugs into an artery.
Radiography of blood vessels after injection of a contrast medium.
A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
The hospital department responsible for the administration and provision of diagnostic and therapeutic services for the cardiac patient.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
The creation and display of functional images showing where the blood is flowing into the MYOCARDIUM by following over time the distribution of tracers injected into the blood stream.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Preliminary administration of a drug preceding a diagnostic, therapeutic, or surgical procedure. The commonest types of premedication are antibiotics (ANTIBIOTIC PROPHYLAXIS) and anti-anxiety agents. It does not include PREANESTHETIC MEDICATION.
Endovascular procedure in which atheromatous plaque is excised by a cutting or rotating catheter. It differs from balloon and laser angioplasty procedures which enlarge vessels by dilation but frequently do not remove much plaque. If the plaque is removed by surgical excision under general anesthesia rather than by an endovascular procedure through a catheter, it is called ENDARTERECTOMY.
Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Epidemiologic investigations designed to test a hypothesized cause-effect relation by modifying the supposed causal factor(s) in the study population.
Surgery which could be postponed or not done at all without danger to the patient. Elective surgery includes procedures to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risk to patients, e.g., cosmetic or contraceptive surgery.
Works about controlled studies which are planned and carried out by several cooperating institutions to assess certain variables and outcomes in specific patient populations, for example, a multicenter study of congenital anomalies in children.
Methods of creating machines and devices.
The larger of the two terminal branches of the brachial artery, beginning about one centimeter distal to the bend of the elbow. Like the RADIAL ARTERY, its branches may be divided into three groups corresponding to their locations in the forearm, wrist, and hand.
Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Motion pictures of the passage of contrast medium through blood vessels.
Evaluation procedures that focus on both the outcome or status (OUTCOMES ASSESSMENT) of the patient at the end of an episode of care - presence of symptoms, level of activity, and mortality; and the process (ASSESSMENT, PROCESS) - what is done for the patient diagnostically and therapeutically.
Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).
The degree to which BLOOD VESSELS are not blocked or obstructed.
A characteristic symptom complex.
Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
The hollow, muscular organ that maintains the circulation of the blood.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
The period of confinement of a patient to a hospital or other health facility.
Institutions with an organized medical staff which provide medical care to patients.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
Antibodies produced by a single clone of cells.
Techniques for controlling bleeding.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Drugs that act on blood and blood-forming organs and those that affect the hemostatic system.
A malformation that is characterized by a muscle bridge over a segment of the CORONARY ARTERIES. Systolic contractions of the muscle bridge can lead to narrowing of coronary artery; coronary compression; MYOCARDIAL ISCHEMIA; MYOCARDIAL INFARCTION; and SUDDEN CARDIAC DEATH.
Conveying ill or injured individuals from one place to another.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Heterocyclic compounds that contain 4H,5H,6H,7H-thieno[2,3-c]pyridine as part of their structure.
A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
After percutaneous coronary interventions (PCIs), such as the placement of a coronary artery stent, a U.S. Agency for ... National Guideline Clearinghouse (NGC). "2011 ACCF/AHA/SCAI guideline for percutaneous coronary artery intervention. A report ... For the prevention of myocardial infarction (MI) in someone with documented or suspected coronary artery disease, much lower ... May 2007). "Aspirin resistance in patients with stable coronary artery disease with and without a history of myocardial ...
For example percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG). Both PCI and CABG are effective at ...
"Remote Ischemic Conditioning in Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting". Circulation Journal. ... The development of CIN after percutaneous coronary intervention is independently associated with an increased risk of short- ... "Myocardial infarction after percutaneous coronary intervention: a meta-analysis of troponin elevation applying the new ... patients when used in the ambulance or emergency department as an adjunct therapy to primary percutaneous coronary intervention ...
After percutaneous coronary interventions (PCIs), such as the placement of a coronary artery stent, a U.S. Agency for ... "2011 ACCF/AHA/SCAI guideline for percutaneous coronary artery intervention. A report of the American College of Cardiology ... Hall SL, Lorenc T (February 2010). "Secondary prevention of coronary artery disease". American Family Physician. 81 (3): 289-96 ... in someone with documented or suspected coronary artery disease, much lower doses are taken once daily.[82] ...
IRE has been suggested as preventive treatment for coronary artery re-stenosis after percutaneous coronary intervention.[ ... August 2014). "Percutaneous irreversible electroporation for the treatment of colorectal cancer liver metastases with a ... April 2016). "Percutaneous Ablation of Hepatic Tumors Using Irreversible Electroporation: A Prospective Safety and Midterm ... March 2017). "Percutaneous Irreversible Electroporation: Long-term survival analysis of 71 patients with inoperable malignant ...
In the past they have been used for saphenous vein graft and native coronary artery percutaneous coronary interventions. Self- ... Rarely, SEMS may fracture or intussescept after endoscopic intervention. Vitale G, Davis B, Tran T (2005). "The advancing art ... Mauro M, Koehler R, Baron T (2000). "Advances in gastrointestinal intervention: the treatment of gastroduodenal and colorectal ...
National Guideline Clearinghouse (NGC). 2011 ACCF/AHA/SCAI guideline for percutaneous coronary artery intervention. A report of ... Hall, SL; Lorenc, T. Secondary prevention of coronary artery disease. American family physician. 2010-02-01, 81 (3): 289-96. ... Aspirin Resistance in Patients with Stable Coronary Artery Disease with and without a History of Myocardial Infarction. Annals ... Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions.. United ...
A number of procedures may also be carried out such as percutaneous coronary intervention, coronary artery bypass graft, or ... A number of procedures may also be carried out such as percutaneous coronary intervention, coronary artery bypass graft, or ... it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which arteries ... While coronary artery disease is more prevalent in men than women, atherosclerosis of the cerebral arteries and strokes equally ...
Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe ... "Coronary artery bypass graft surgery vs percutaneous interventions in coronary revascularization: a systematic review". JAMA. ... As the left and right coronary arteries run on the surface of the heart, they can be called epicardial coronary arteries. These ... The coronary arteries that run deep within the myocardium are referred to as subendocardial.[citation needed] The coronary ...
... of heart attacks since the age of 38 and has undergone coronary artery bypass surgery and percutaneous coronary interventions. ... After an intensive session at the gym, Drake suffered a heart attack and was diagnosed with diffuse coronary artery disease, ...
... percutaneous coronary intervention, or coronary artery bypass graft. A jugular venous distension is the most sensitive clinical ... Is a procedure used to improve the symptoms of coronary artery disease (CAD), reduce the damage to the heart muscle after a ... Different procedures are available depending on the level of necessity and include coronary artery bypass surgery, heart valve ... or an artery from the chest and replacing the blocked artery in the heart. This allows the blood to flow more freely through ...
Percutaneous coronary intervention (PCI), coronary artery bypass surgery (CABG)[10]. 藥物. Aspirin, beta blockers, nitroglycerin( ... Coronary artery bypass graft surgery vs percutaneous interventions in coronary revascularization: a systematic review.. JAMA. ... coronary artery disease, CAD)又稱為缺血性心臟病或簡稱冠心病(英语:ischemic heart disease, IHD)[13]、冠狀動脈粥狀硬化心臟病[14]、冠狀動脈粥狀硬化心血管疾病(英语:coronary ... Coronary heart disease. NIH. [15 September 2013].. *^ 4.0 4.1 4.2 4.3 4.4 What
... a new strategy to avoid early bleeding and subacute radial artery occlusion after percutaneous coronary intervention". J ... "A new kaolin-based haemostatic bandage compared with manual compression for bleeding control after percutaneous coronary ...
For coronary artery disease (ischemic heart disease), coronary artery bypass surgery and percutaneous coronary intervention ( ... Kalyanasundaram, Arun (April 5, 2012). "Comparison of Revascularization Procedures in Coronary Artery Disease". Drugs, Diseases ... When those cannot be done, transmyocardial revascularization or percutaneous myocardial revascularization, done with a laser, ... coronary balloon angioplasty) are the two primary means of revascularization. ...
If the blockage is not relieved promptly by medication, percutaneous coronary intervention, or surgery, then a heart muscle ... If a coronary artery suddenly becomes very narrowed or completely blocked, interrupting or severely reducing blood flow through ... Blood is brought to the myocardium by the coronary arteries. These originate from the aortic root and lie on the outer or ... In ischaemic heart disease, the coronary arteries become narrowed by atherosclerosis. If these narrowings gradually become ...
Madani Heart Center serves as the main hospital for Angiography, Percutaneous Coronary Intervention (PCI), Coronary Artery ... heart emergency care section and Coronary Care Unit (CCU). Madanai Heart Center was a part of Imam Khomeini Hospital before ...
"Coronary artery bypass graft surgery vs percutaneous interventions in coronary revascularization: a systematic review". JAMA. ... Coronary artery diseaseEdit. Main article: Coronary artery disease. Coronary artery disease, also known as "ischemic heart ... Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe ... As the left and right coronary arteries run on the surface of the heart, they can be called epicardial coronary arteries. These ...
Transradial artery access (TRA) and transfemoral artery access (TFA) are two techniques for percutaneous coronary intervention ... coronary arteries of the heart found in coronary heart disease. These stenotic segments of the coronary arteries arise due to ... A percutaneous coronary intervention (PCI), or coronary angioplasty with stenting, is a non-surgical procedure used to improve ... Percutaneous transluminal coronary angioplasty (PTCA) is contraindicated in patients with left main coronary artery disease, ...
"Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left ... The first procedure to treat blocked coronary arteries was coronary artery bypass graft surgery (CABG), wherein a section of ... "Nonoperative dilatation of coronary-artery stenosis: percutaneous transluminal coronary angioplasty". New England Journal of ... 2008). "Percutaneous coronary intervention without on site surgical back-up; two-years registry of a large dutch community ...
May 2007). "Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study". J ... is a technique used in coronary catheterization to measure pressure differences across a coronary artery stenosis (narrowing, ... The decision to perform a percutaneous coronary intervention (PCI) is usually based on angiographic results alone. Angiography ... In 20 centers in Europe and the United States, 1005 patients undergoing percutaneous coronary intervention with drug eluting ...
Coronary artery bypass surgery versus percutaneous coronary intervention with stent implantation in patients with multivessel ... study aimed at comparing percutaneous coronary intervention employing stents with the relatively well-accepted coronary bypass ... Lancet 1995;346:211-214 Sigwart U, Grbic M, Payot M, Goy J-J, Essinger A, et al.: Ischemic events during coronary artery ... Coronary Stents, Springer 1992 (ISBN 9780387545417) (Coronary Stents) U. Sigwart: Endoluminal Stenting, W. B. Saunders 1996 ( ...
... to administer ticagrelor to patients with stable coronary artery disease undergoing percutaneous coronary intervention after ... however if there is a plan for percutaneous coronary intervention (PCI), administration of thrombolysis or the presence of some ... in decreasing ischemic events and the total mortality independent of patients undergoing percutaneous coronary intervention. ... meaning problems with blood supply in the coronary arteries. It acts as a platelet aggregation inhibitor by antagonising the ...
The institute's volumes in coronary artery bypass graft surgery and percutaneous coronary intervention are among the highest in ... end results of health care practices and interventions) The research is conducted in settings that include both hospital and ...
... or percutaneous coronary intervention (PCI) are not available or possible. Despite the trial's limitations (i.e. no assessment ... into patients with coronary artery disease in hopes of re-vascularizing damaged tissue in patients for which coronary artery ... Human HGF plasmid DNA therapy of cardiomyocytes is being examined as a potential treatment for coronary artery disease (a major ... "Phase I clinical trial on intracoronary administration of Ad-hHGF treating severe coronary artery disease". Molecular Biology ...
2005). "Comparison of percutaneous coronary intervention and coronary artery bypass grafting after acute myocardial infarction ... or percutaneous coronary intervention (and coronary angioplasty) is then performed. Percutaneous coronary intervention in this ... The use of a coronary angioplasty to abort a myocardial infarction is preceded by a primary percutaneous coronary intervention ... Coronary artery bypass surgery involves an artery or vein from the patient being implanted to bypass narrowings or occlusions ...
IVOCT has been used as guidance for angioplasty intervention of coronary arteries, including optimization of stent implantation ... Evidence showed that intracoronary OCT can be used to optimize percutaneous coronary intervention to treat myocardial ... "Optical coherence tomography imaging during percutaneous coronary intervention impacts physician decision-making: ILUMIEN I ... two intracoronary OCT catheters are clinically available for use in the coronary arteries, having a size in diameter between ...
Percutaneous coronary intervention (PCI) - Procedures to treat stenotic coronary arteries by accessing through a blood vessel. ... Coronary artery disease (CAD)- Coronary artery disease is a general term for any reduction in coronary circulation. One such ... Coronary artery bypass surgery (CABG): Grafting an artery or vein from elsewhere to bypass a stenotic coronary artery. ... Carotid artery - Diseases of the carotid arteries: Carotid artery stenosis / carotid artery disease - Narrowing of the carotid ...
Clinically significant CAV may require percutaneous coronary interventions for focal disease, but the likelihood of restenosis ... This can be seen to affect the whole length of the coronary arteries and often the smaller arteries. Calcification does not ... characteristically demonstrates diffuse stenoses in large coronary arteries and a reduced number of smaller coronary arteries, ... Similar to coronary artery disease in those who have not had a heart transplant, risk factors to CAV include high blood ...
Recently, it's been approved for adult patients undergoing percutaneous coronary intervention (PCI). Cangrelor is a high- ... it is a more desirable drug for elective treatment of stenotic coronary arteries, high risk acute coronary syndromes treated ... May 2014). "Cangrelor: an emerging therapeutic option for patients with coronary artery disease". Current Medical Research and ... without increasing major bleeding in the treatment of stenotic coronary arteries. The advantages of this drug combination are ...
If the narrowings in coronary arteries are unsuitable for treatment with a percutaneous coronary intervention, open surgery may ... These are the left main coronary artery and the right coronary artery. The left main coronary artery splits shortly after ... the left main coronary artery and the right coronary artery. The heart wall is made up of three layers: the inner endocardium, ... This may be performed using a percutaneous coronary intervention, during which narrowings can be expanded by passing small ...
Incidence, management, and outcome of coronary artery perforation during percutaneous coronary intervention. Am J Cardiol2000; ... coronary rupture. Vessel perforation during or following percutaneous coronary intervention (PCI) is a rare complication of ... Coronary artery perforation with sequelae during intervention is rare. This complication is seen in the treatment of chronic ... Conclusions: Coronary artery perforation with sequelae during intervention is rare-26 of 6245 (0.4%). This complication was ...
... or coronary artery bypass grafting can be chosen for the treatment of multiple-vessel coronary artery disease. We report the ... BACKGROUND: Either percutaneous coronary intervention (PCI) or coronary artery bypass grafting can be chosen for the treatment ... Percutaneous Coronary*. Coronary Artery Disease / surgery. Feasibility Studies. Female. Humans. Internal Mammary-Coronary ... combining PCI of the right coronary artery and internal mammary artery bypass grafting of the left coronary artery, for the ...
Cardiologists use of percutaneous coronary interventions for stable coronary artery disease. Arch Intern Med2007;167:1604-9. ... Percutaneous coronary interventions for non-acute coronary artery disease: a quantitative 20-year synopsis and a network meta- ... Percutaneous coronary intervention versus optimal medical therapy in stable coronary artery disease: a systematic review and ... Reported perceptions of percutaneous coronary intervention by patients with stable coronary artery disease ...
Coronary artery bypass graft surgery is arguably the most intensively studied surgical procedure, and percutaneous coronary ... Objective: This review compares and contrasts outcomes from two coronary revascularization techniques, coronary artery bypass ... drove differences in primary endpoints and in all but the patients with low Synergy Between Percutaneous Coronary Intervention ... Current data support the use of percutaneous intervention in ST elevation myocardial infarction and in single-vessel disease. ...
Review: CABG and percutaneous coronary intervention do not differ for long-term mortality in multivessel coronary artery ... Coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) are alternative treatments for multivessel ... Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative ... effectiveness of multivessel coronary artery bypass graft surgery and multivessel percutaneous coronary intervention. [Ann ...
Coronary artery bypass grafting surgery versus percutaneous coronary intervention for coronary artery disease. To assess the ... Coronary artery bypass grafting surgery versus percutaneous coronary intervention for coronary artery disease. Cochrane ... Tong-xin-luo capsule for patients with coronary heart disease after percutaneous coronary intervention ... Xiongshao capsule preventing restenosis after percutaneous coronary intervention in patients with coronary heart disease ...
The 2 primary methods of revascularization are coronary artery bypass graft and percutaneous coronary intervention, but the ... Coronary artery bypass graft versus percutaneous coronary intervention in acute heart failure. Heart. 2020:106(1):50-57. doi: ... The 2 primary methods of revascularization are coronary artery bypass graft and percutaneous coronary intervention, but the ... The 2 primary methods of revascularization are coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI ...
... caused an acute ST-elevation myocardial infarction and it was treated successfully with a percutaneous coronary intervention. ... We report a case of mitral valve repair complicated by iatrogenic coronary artery lesion. This rare coronary injury ... We report a case of mitral valve repair complicated by iatrogenic coronary artery lesion. This rare coronary injury caused an ... acute ST-elevation myocardial infarction and it was treated successfully with a percutaneous coronary intervention.. ...
COURAGE or FAME…? Who should have percutaneous coronary intervention in stable coronary artery disease? ... COURAGE or FAME…? Who should have percutaneous coronary intervention in stable coronary artery disease? ...
2005) Percutaneous coronary intervention versus conservative therapy in nonacute coronary artery disease: a meta-analysis. ... 2003) Indications for coronary artery bypass surgery and percutaneous coronary intervention in chronic stable angina: review of ... percutaneous coronary intervention. PTCA. percutaneous transluminal coronary angioplasty. TLR. target lesion revascularization ... and temporal trends among patients undergoing percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD ...
Coronary Artery Disease. Robotic Coronary Artery Bypass Surgery. Percutaneous Coronary Intervention. Hybrid Coronary ... Robotic Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Coronary Artery Disease. ... Robotic Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Coronary Artery Disease. ... and percutaneous coronary intervention (PCI) in the treatment of obstructive multivessel coronary artery disease. A secondary ...
Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery ...
Cost-Effectiveness of Coronary Artery Bypass Grafts Versus Percutaneous Coronary Intervention for Revascularization of High- ... Cost-Effectiveness of Coronary Artery Bypass Grafts Versus Percutaneous Coronary Intervention for Revascularization of High- ... Cost-Effectiveness of Coronary Artery Bypass Grafts Versus Percutaneous Coronary Intervention for Revascularization of High- ... Cost-Effectiveness of Coronary Artery Bypass Grafts Versus Percutaneous Coronary Intervention for Revascularization of High- ...
2011) Percutaneous coronary intervention in native arteries versus bypass grafts in prior coronary artery bypass grafting ... Percutaneous Coronary Interventions Following Coronary Artery Bypass Graft. Grigorios Tsigkas, Ioanna Xanthopoulou, Dimitrios ... Percutaneous Coronary Interventions Following Coronary Artery Bypass Graft. Grigorios Tsigkas, Ioanna Xanthopoulou, Dimitrios ... Percutaneous Coronary Interventions Following Coronary Artery Bypass Graft Message Subject (Your Name) has forwarded a page to ...
... in Native Coronary Arteries. Microembolization of particulate debris during percutaneous coronary intervention (PCI) will lead ... Use of Distal Protection Device for Percutaneous Intervention in Native Coronary Arteries. Kenneth Ka-Hing Lam, Shu-Kin Li. ... Key words : Distal protection, microembolization, microvascular obstruction, percutaneous coronary intervention. Back to ... coronary interventions. While its value has been confirmed in saphenous vein grafts intervention, data is now growing to ...
"Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Coronary Artery Disease in ... Multivessel Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention in ESRD. Tara I. Chang, David Shilane, ... Multivessel Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention in ESRD. Tara I. Chang, David Shilane, ... Multivessel Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention in ESRD. Tara I. Chang, David Shilane, ...
Cardiovascular Mortality In ESRD Patients Undergoing Coronary Artery Bypass Grafting Vs Percutaneous Coronary Intervention- A ... Cardiovascular Mortality In ESRD Patients Undergoing Coronary Artery Bypass Grafting Vs Percutaneous Coronary Intervention- A ... Cardiovascular Mortality In ESRD Patients Undergoing Coronary Artery Bypass Grafting Vs Percutaneous Coronary Intervention- A ... Cardiovascular Mortality In ESRD Patients Undergoing Coronary Artery Bypass Grafting Vs Percutaneous Coronary Intervention- A ...
Percutaneous coronary intervention vs. coronary artery bypass graft surgery for unprotected left main coronary artery disease ... Patients with unprotected left main coronary artery (LMCA) disease are increasingly treated with percutaneous coronary ... intervention (PCI) using drug-eluting stents (DES), but its benefits compared with coronary artery bypass grafting (CABG) ...
Effectiveness of Multivessel Coronary Artery Bypass Graft Surgery and Multivessel Percutaneous Coronary Intervention Junji ... Comparative Effectiveness of Multivessel Coronary Bypass Surgery and Multivessel Percutaneous Coronary Intervention: A Cohort ... Effectiveness of Multivessel Coronary Artery Bypass Graft Surgery and Multivessel Percutaneous Coronary Intervention. Ann ... Effectiveness of Multivessel Coronary Artery Bypass Graft Surgery and Multivessel Percutaneous Coronary Intervention ...
With Percutaneous Coronary Intervention for Proximal Left Anterior Descending Artery Treatment in Patients With Acute Coronary ... PubMed journal article Coronary Artery Bypass Surgery Compared ... Acute Coronary SyndromeAgedCoronary AngiographyCoronary Artery ... Coronary Artery Bypass Surgery Compared With Percutaneous Coronary Intervention for Proximal Left Anterior Descending Artery ... "Coronary Artery Bypass Surgery Compared With Percutaneous Coronary Intervention for Proximal Left Anterior Descending Artery ...
Risk of restenosis and health status outcomes for patients undergoing percutaneous coronary intervention versus coronary artery ... percutaneous coronary intervention or medical management.. *Outcomes of coronary artery bypass grafting versus percutaneous ... Comparison of coronary artery bypass surgery with percutaneous coronary intervention with drug-eluting stents for unprotected ... Previous comparisons of percutaneous coronary interventions (PCIs) and coronary artery bypass graft (CABG) surgery have ...
Coronary artery bypass graft (CABG) vs percutaneous coronary intervention (PCI) in patients with multivessel coronary artery ... In patients with multivessel coronary artery disease, coronary artery bypass grafting (CABG) and percutaneous coronary ... Percutaneous coronary intervention was not as effective as CABG for severe coronary artery disease Annals of Internal Medicine; ... Percutaneous coronary intervention was not as effective as CABG for severe coronary artery disease Annals of Internal Medicine; ...
January 2007 Coronary Artery Disease and Percutaneous Coronary Intervention in a Set of Twins ... Coronary Artery Disease and Percutaneous Coronary Intervention in a Set of Twins ... with no significant angiographic stenosis in the remaining arteries. An ad hoc percutaneous coronary intervention was performed ... Coronary angiography showed a severe lesion in the middle right coronary artery, but no significant lesions in the remaining ...
Percutaneous Coronary Intervention Choice Decision Aid for Stable Coronary Artery Disease. A Randomized Trial. Megan ... Percutaneous Coronary Intervention Choice Decision Aid for Stable Coronary Artery Disease. Megan Coylewright, Sara Dick, Becky ... Percutaneous Coronary Intervention Choice Decision Aid for Stable Coronary Artery Disease. Megan Coylewright, Sara Dick, Becky ... Background-Percutaneous coronary intervention (PCI) for stable coronary artery disease does not reduce the risk of death and ...
Long-term outcomes of percutaneous coronary intervention in grafts and native vessels in coronary artery bypass grafting ... Reassessing Coronary Artery Bypass Surgery Versus Percutaneous Coronary Intervention in Patients with Type 2 Diabetes Mellitus ... Long-term outcomes of percutaneous coronary intervention in grafts and native vessels in coronary artery bypass grafting ... Long-term outcomes of percutaneous coronary intervention in grafts and native vessels in coronary artery bypass grafting ...
... coronary intervention for ostial lesions of the left main stem in a patient with congenital single left coronary artery: A case ... Figure 3 Coronary angiograms after percutaneous coronary intervention. A: Caudal view; B: Right anterior oblique cranial view. ... Percutaneous coronary intervention for ostial lesions of the left main stem in a patient with congenital single left coronary ... Percutaneous coronary intervention for ostial lesions of the left main stem in a patient with congenital single left coronary ...
2009 - Review: CABG and percutaneous coronary intervention do not differ for long-term mortality in multivessel coronary artery ... CABG and percutaneous coronary intervention do not differ for long-term mortality in multivessel coronary artery disease ... The treatment of coronary artery disease, initially by medical and surgical and subsequently using percutaneous interventions, ... The article focuses on a study on modification of the relative effects of percutaneous coronary intervention (PCI) and coronary ...
Percutaneous Coronary Intervention / Chronic Total Occlusion of Coronary Artery Treatment. Back to Rosuvastatin ... Rosuvastatin Enrolling by Invitation Phase 4 Trials for Coronary Artery Disease / Viable Myocardium / ... DBCOND0030679 (Percutaneous Coronary Intervention). *DBCOND0047224 (Chronic Total Occlusion of Coronary Artery). Enrolling by ...
Outcomes of Primary Percutaneous Coronary Interventions Performed at Hospitals With and Without On-Site Coronary Artery Bypass ... Background Primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) is performed in hospitals ... without on-site coronary artery bypass graft surgery in the `real world. However, data on the in-hospital outcomes of primary ... Excluding patients without adequate data, we retrospectively compared clinical background, coronary risk factors, angiographic ...
High density lipoprotein cholesterol as a predictor of clinical outcomes in patients with coronary artery disease undergoing ... percutaneous coronary intervention with normal initial low density lipoprotein cholesterol for Abdel mawgood Rany Elsayed ... as a predictor of clinical outcomes in patients with coronary artery disease undergoing percutaneous coronary intervention with ... as a predictor of clinical outcomes in patients with coronary artery disease undergoing percutaneous coronary intervention with ...
  • This review compares and contrasts outcomes from two coronary revascularization techniques, coronary artery bypass grafting (CABG) and PCI, with particular reference to the landmark trials that inform practice guidelines. (dovepress.com)
  • In these trials, revascularization drove differences in primary endpoints and in all but the patients with low Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac surgery score, rates of revascularization were significantly lower with CABG. (dovepress.com)
  • Coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) are alternative treatments for multivessel coronary disease. (nih.gov)
  • Long-term mortality is similar after CABG and PCI in most patient subgroups with multivessel coronary artery disease, so choice of treatment should depend on patient preferences for other outcomes. (nih.gov)
  • PCI or CABG in coronary artery disease? (nih.gov)
  • CABG versus PCI for multivessel coronary artery disease. (nih.gov)
  • Review: CABG and percutaneous coronary intervention do not differ for long-term mortality in multivessel coronary artery disease. (nih.gov)
  • The 2 primary methods of revascularization are coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI). (ajmc.com)
  • The primary objective of this study is to assess the safety and effectiveness of same sitting, simultaneous hybrid robotic assisted coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in the treatment of obstructive multivessel coronary artery disease. (clinicaltrials.gov)
  • The study population will consist of patients with multivessel coronary artery disease requiring CABG with suitable anatomy for combination CABG and PCI of non-bypassed arteries. (clinicaltrials.gov)
  • Background- A Department of Veterans Affairs Cooperative Study randomized high-risk patients with medically refractory myocardial ischemia, a group largely excluded from previous trials, to urgent revascularization with either percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). (ahajournals.org)
  • 1 204 000 percutaneous coronary intervention (PCI) procedures and 306 000 coronary artery bypass grafting (CABG) surgeries were performed in 2002. (ahajournals.org)
  • The multicenter, randomized, controlled AWESOME trial evaluated the survival of high-risk patients who underwent coronary revascularization with either PCI or CABG, as described in detail previously. (ahajournals.org)
  • 1 ) concerning percutaneous coronary interventions (PCI) following coronary artery bypass graft (CABG). (onlinejacc.org)
  • We used data from the United States Renal Data System to define a cohort of 21,981 patients on maintenance dialysis who received initial coronary revascularization with either coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) between 1997 and 2009 and had at least 6 months of prior Medicare coverage as their primary payer. (asnjournals.org)
  • In the absence of data from randomized trials, these results suggest that CABG may be preferred over PCI for multivessel coronary revascularization in appropriately selected patients on maintenance dialysis. (asnjournals.org)
  • Although there have been several randomized trials comparing multivessel coronary artery bypass grafting (CABG) with multivessel percutaneous coronary intervention (PCI), 5 , 6 none of these trials included patients with ESRD. (asnjournals.org)
  • We restricted our analysis to patients undergoing multivessel coronary revascularization to minimize indication bias, because they have the most similar likelihood of receiving either CABG or PCI. (asnjournals.org)
  • We identified 21,981 patients who received initial coronary revascularization with multivessel CABG or multivessel PCI between 1997 and 2009 and met the inclusion and exclusion criteria ( Figure 1 ). (asnjournals.org)
  • In patients with ESRD, CABG is associated with decreased mortality when compared to percutaneous coronary intervention. (ahajournals.org)
  • Patients with unprotected left main coronary artery (LMCA) disease are increasingly treated with percutaneous coronary intervention (PCI) using drug-eluting stents (DES), but its benefits compared with coronary artery bypass grafting (CABG) remain controversial. (nih.gov)
  • Although we commend Hlatky and colleagues (1) for their attempts to assess the clinical characteristics that could modify the comparative effectiveness of coronary artery bypass graft (CABG) surgery versus percutaneous coronary intervention (PCI) in an unselected general population, the limitation of propensity score analysis when several unmeasured confounding factors are present should be emphasized. (annals.org)
  • McNulty and associates (2) explicitly identified that these factors contributed to the ineligibility for CABG in more than 50% of patients having PCI for left main coronary artery disease, and ineligible patients have a 5-fold risk for death compared with eligible patients. (annals.org)
  • The aim of this study was to compare the outcomes of ACS patients with pLAD culprit lesions receiving percutaneous coronary intervention (PCI) vs coronary artery bypass graft (CABG). (unboundmedicine.com)
  • Previous comparisons of percutaneous coronary interventions (PCIs) and coronary artery bypass graft (CABG) surgery have demonstrated similar survival but have also generally found better health status outcomes (symptoms, function, and quality of life) with CABG. (unboundmedicine.com)
  • Evidence on how to choose target vessels of percutaneous coronary interventions (PCIs) in diabetic patients post-coronary artery bypass graft (post-CABG) is insufficient. (medworm.com)
  • Results: Diabetic patients with prior CABG had more PCI to native arteries, but the proportion of grafts PCI increased as time went on. (medworm.com)
  • AbstractPurpose of ReviewTo review the clinical evidence on the use of percutaneous coronary intervention (PCI) revascularization options in left main (LM) disease in comparison with coronary artery bypass graft (CABG). (medworm.com)
  • Though CABG remains the gold standard for complex CAD involving the LM artery, recent trials have shown a trend towards non-inferiority of the LM PCI when compared with CABG in certain subset of patients.Recent FindingsTwo recent major randomized trials compared the outcomes of PCI versus CABG in the LM and multi. (medworm.com)
  • The article focuses on a study on modification of the relative effects of percutaneous coronary intervention (PCI) and coronary artery bypass grafting(CABG) by patient characteristics on long-term mortality in patients with multivessel coronary artery disease (CAD). (ebscohost.com)
  • On the contrary, if the coronary angiogram shows a triple-vessel disease and left main disease, then one has to look for comorbidities that put the patient at a higher risk of CABG and the patient should be treated with PCI. (pubmedcentralcanada.ca)
  • Here we focus on the role of revascularization strategies [percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG)] in the management of chronic stable angina. (pubmedcentralcanada.ca)
  • 1 Coronary artery bypass graft (CABG) surgery has been the standard of care for the treatment of ULMCA disease, and percutaneous coronary intervention (PCI) is reserved for patients who are poor surgical candidates. (hkmj.org)
  • Background: The Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) trial was a non-inferiority trial that compared percutaneous coronary intervention (PCI) using first-generation paclitaxel-eluting stents with coronary artery bypass grafting (CABG) in patients with de-novo three-vessel and left main coronary artery disease, and reported results up to 5 years. (eur.nl)
  • Patients with de-novo three-vessel and left main coronary artery disease were randomly assigned (1:1) to the PCI group or CABG group. (eur.nl)
  • Among patients with three-vessel disease, 151 (28%) of 546 had died after PCI versus 113 (21%) of 549 after CABG (hazard ratio 1·41 [95% CI 1·10-1·80]), and among patients with left main coronary artery disease, 93 (26%) of 357 had died after PCI versus 98 (28%) of 348 after CABG (0·90 [0·68-1·20], pinteraction=0·019). (eur.nl)
  • However, CABG provided a significant survival benefit in patients with three-vessel disease, but not in patients with left main coronary artery disease. (eur.nl)
  • Fifty patients underwent percutaneous coronary intervention (PCI) with drug-eluting stents (DES), and 123 patients underwent coronary artery bypass graft (CABG) surgery for unprotected left main coronary artery (ULMCA) disease at our institution. (onlinejacc.org)
  • Objectives This study evaluated the clinical outcomes of consecutive, selected patients treated with coronary artery bypass graft (CABG) surgery or percutaneous coronary intervention (PCI) with drug-eluting stents (DES) for unprotected left main coronary artery (ULMCA) disease. (onlinejacc.org)
  • We aimed to compare the long-term performance of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery in treatment of left main CAD. (biomedcentral.com)
  • To compare long-term outcomes of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG), accounting for the clinical impact of individual components in composite endpoints and prioritizing these using the win ratio (Rw). (pcronline.com)
  • Fernández-Ruiz I. Coronary artery disease: CABG surgery or PCI for left main CAD? (amegroups.com)
  • Coronary artery bypass grafting (CABG) has historically been the standard of care for management of left main coronary artery disease (LMCAD). (amegroups.com)
  • Such results of sub-analyses of larger randomized trials formed the basis for two recently published trials comparing CABG vs. PCI in LMCAD-Nordic-Baltic-British Left Main Revascularization (NOBLE) and Evaluation of XIENCE vs. Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization (EXCEL) ( 9 , 10 ). (amegroups.com)
  • To evaluate the usefulness of the SYNTAX score (SS) in predicting 1-year clinical outcomes in a population of patients with chronic coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). (benthamopen.com)
  • He then underwent coronary artery bypass grafting (CABG). (biomedcentral.com)
  • Although revascularization improves outcomes, procedural risks are increased in CKD, and unbiased data comparing coronary artery bypass grafting (CABG) and percutaneous intervention (PCI) in CKD are sparse. (bris.ac.uk)
  • Few randomized controlled trials (RCTs) and observational studies had shown acceptable short-term efficacy and safety of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) compared with coronary artery bypass grafting (CABG) in selected patients with left main coronary artery disease (LMCAD). (qxmd.com)
  • The patient requires any concomitant surgical procedures (e.g., carotid artery, CABG) during the PCI. (clinicaltrials.gov)
  • Acute occlusion of the left internal mammary artery (LIMA) immediately following coronary artery bypass surgery (CABG) is a rare complication that is usually treated by repeat emergency surgery. (imedpub.com)
  • As intraoperative blood flow control by Doppler showed intermittent flow despite optimal anastomosis, immediate coronary angiogram was performed following CABG and an occlusion of the LIMA graft was documented. (imedpub.com)
  • Angiographically identified severe coronary calcification is a known predictor of adverse clinical outcomes after revascularization with either PCI or coronary artery bypass graft (CABG). (medscape.com)
  • Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are reported with limited data on indications and comparative efficacy. (elsevier.com)
  • Age at intervention (8.3 ± 3.9 vs 11.3 ± 4.9 years, p = 0.14) and interval from diagnosis (5.6 ± 4.1 vs 6.5 ± 4.7 years, p = 0.64) were similar between CABG and PCI. (elsevier.com)
  • Interventions were based on angiography in 15 patients or cardiac event in 7, with no difference between CABG and PCI (p = 0.24). (elsevier.com)
  • Patients with CABG were more likely to undergo multivessel intervention (73 vs 10 %, p = 0.006). (elsevier.com)
  • Signs of ischemia on stress testing or MIBI were present in 15 patients before intervention and persisted in 9 patients following last intervention, in a significantly higher proportion after CABG than PCI (80 vs 17 %, p = 0.01). (elsevier.com)
  • Coronary-artery bypass grafting (CABG) is recommended for left main coronary artery disease and the procedure requires an open-heart surgery that can increase the chances of an infection and other post-surgical adverse event. (inpharmd.com)
  • In patients with left main coronary artery disease and low or intermediate SYNTAX scores by site assessment, PCI with everolimus-eluting stents was non-inferior to CABG with respect to the rate of the composite end point of death, stroke, or myocardial infarction at 30 days and 3 years. (inpharmd.com)
  • For decades, the standard approach to LMCA revascularization has been through coronary artery bypass grafting (CABG) given its ability to safely and effectively achieve complete revascularization. (jamanetwork.com)
  • More recently, revascularization through percutaneous coronary intervention (PCI) has been proposed as an alternative to CABG for traditionally surgical anatomy. (jamanetwork.com)
  • A dramatic increase in percutaneous coronary intervention (PCI), coupled with a similar decrease in coronary artery bypass grafting (CABG) has characterized the treatment of coronary artery disease for the 20 years. (cardiachealth.org)
  • The just released FREEDOM trial results[ 1 ] have once again confirmed that diabetic patients with coronary artery disease have better outcomes with CABG than with PCI - even if contemporaneous techniques are used. (cardiachealth.org)
  • Minimally invasive coronary artery bypass grafting (MICS-CABG) is a safe and effective alternative to conventional CABG. (opencardiovascularmedicinejournal.com)
  • The use of 'Coronary Artery Bypass Grafting' (CABG) rather than 'Percutaneous Coronary Intervention' (PCI) for the management of patients with triple vessel or left main coronary artery disease is associated with lower rates of major adverse cardiac or cerebrovascular events at 1 year. (emedicinelive.com)
  • Korea has seen a rapid increase in the use of percutaneous coronary intervention (PCI) with the ratio of PCI to coronary artery bypass graft (CABG) the highest in the world. (biomedcentral.com)
  • The choice of coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) for the treatment of coronary artery disease has long been a debatable issue. (biomedcentral.com)
  • Many factors have contributed to this, including the introduction of coronary care units, coronary artery bypass grafting (CABG), thrombolytic therapy, percutaneous coronary intervention (PCI), and a renewed emphasis on lifestyle modification. (medscape.com)
  • Coronary artery bypass grafting (CABG) is performed for patients with coronary artery disease (CAD) to improve quality of life and reduce cardiac-related mortality. (medscape.com)
  • CABG may be performed as an emergency procedure in the context of an ST-segment elevation MI (STEMI) in cases where it has not been possible to perform percutaneous coronary intervention (PCI) or where PCI has failed and there is persistent pain and ischemia threatening a significant area of myocardium despite medical therapy. (medscape.com)
  • Patency of the LIMA and stented vessels as determined by coronary angiography at time of procedures or prior to discharge and by cardiac Computed Tomographic Angiography (CTA) or coronary angiography at 1 year. (clinicaltrials.gov)
  • Coronary angiography showed a severe lesion in the middle right coronary artery, but no significant lesions in the remaining coronary vasculature (Figure 2A). (revespcardiol.org)
  • The MI group was evaluated for the use of coronary angiography, coronary artery bypass graft surgery, and percutaneous transluminal. (ebscohost.com)
  • However, there is a paucity of data documenting the feasibility of either coronary angiography and/or PCI after TAVR. (springer.com)
  • We systematically searched Medline, Pubmed, Embase, Cochrane database, Google Scholar, Science Direct, Web of Science, and conference abstracts from conception to March 2020 using OvidSP in TAVR patients undergoing coronary angiography with or without PCI at least 6 months after TAVR. (springer.com)
  • The primary outcome of interest was successful coronary angiography for either the left main coronary artery (LMCA) or right coronary artery (RCA) with or without PCI. (springer.com)
  • The overall achievement of a successful coronary angiography with or without PCI in post-TAVR patients is high, with a lower success rate for RCA angiography in patients with the Medtronic SEV Mortality and bleeding did not differ in our analysis. (springer.com)
  • Recently, the Center of Medicare and Medicaid Services (CMS), supported by the American College of Cardiology (ACC), has expanded the coverage of percutaneous coronary interventions (PCI) at ambulatory centers in the United States of America (USA) [ 6 ], so it is expected more of coronary angiography with or without PCI to be done in non-TAVR centers or even outpatient settings with limited exposure to transcatheter valve interventions. (springer.com)
  • It is therefore essential for the diagnostic and interventional cardiologists to understand the potential challenges of coronary angiography and PCI in this patient population being particularly useful in time-critical scenarios, such as ACS [ 9 ]. (springer.com)
  • We, therefore, undertook a systematic literature review and meta-analysis of studies examining the feasibility of delayed coronary angiography with or without PCI and its clinical outcomes in patients who underwent TAVR. (springer.com)
  • If the patients' symptoms are not controlled in spite of these drugs being used in maximum tolerated dosages, then these patients should be subjected to coronary angiography. (pubmedcentralcanada.ca)
  • Significant unprotected left main coronary artery (ULMCA) disease occurs in 5% to 7% of patients undergoing coronary angiography. (hkmj.org)
  • Background In patients with multivessel CAD undergoing PCI, coronary angiography is the standard method for guiding stent placement. (onlinejacc.org)
  • Final angiography demonstrated favorable dilatation of the target lesion, and native blood flow in the right coronary artery was completely recovered. (biomedcentral.com)
  • Coronary computed tomography angiography (CTA ) demonstrated that the RCA coursed anteriorly between the aorta and pulmonary artery, the so-called 'interarterial course', and then in the atrioventricular (AV) groove to continue its normal distribution. (biomedcentral.com)
  • Routine coronary angiography after surgery demonstrated complete graft patency and unexpected spontaneous reperfusion in the culprit lesion of ACS. (biomedcentral.com)
  • The medical records of 998 patients who were diagnosed as STEMI and underwent emergency coronary angiography were retrospectively studied, SR was defined as achievement of TIMI grade 3 flow in the IRA before PCI. (biomedcentral.com)
  • This retrospective, single center observational study was based on review of medical records, electrocardiographic analysis and cardiac catheterization films of 998 consecutive patients presenting from January 1,2012 through January 1,2015 to China-JapanFriendshipHospital (Beijing, China) with suspected acute STEMI, who underwent emergency coronary angiography on admission within 12 h of symptom onset and activation of the emergency PCI protocol. (biomedcentral.com)
  • Study population was categorized according to the presence of moderate or severe versus mild or no target lesion CAC, assessed through coronary angiography. (elsevier.com)
  • The need for post-TAVR coronary angiography (CA) or percutaneous coronary intervention (PCI) was thus far relatively rare amongst initial TAVR cohorts who were deemed either inoperable or at high-to-extreme surgical risk. (hindawi.com)
  • All patients received successful PPCI (defined as coronary angiography with optimized flow of TIMI grade 3) within 12 h from symptom onset. (hindawi.com)
  • Serum high-sensitivity cardiac troponin- T was mildly elevated at 23 ng/L (upper limit of normal 14 ng/L). The patient was diagnosed with non-ST elevation myocardial infarction (NSTEMI) and underwent same day coronary angiography by radial approach. (imedpub.com)
  • Coronary angiography showed single-vessel coronary artery disease with a severe ostial LAD stenosis. (imedpub.com)
  • For that reason, emergent coronary angiography was performed immediately after surgery, which showed an occlusion of the LIMA graft ( Figure 1 ). (imedpub.com)
  • Coronary angiography revealed right dominant coronary circulation, two-vessel disease with subtotal stenosis of left circumflex artery (LCX) and long 75% lesion of mid portion of right coronary artery (RCA). (hvt-journal.com)
  • The same physician who does the diagnostic coronary angiography, recommends the treatment, and performs the PCI immediately. (cardiachealth.org)
  • In this study, we describe a radial artery perforation that occurred after diagnostic coronary angiography and during insertion of a 6 French (FR) guiding catheter . (bvsalud.org)
  • Cardiac catheterization and coronary angiography in the left panel shows severe left anterior descending coronary artery stenosis. (medscape.com)
  • Cardiac catheterization disclosed severe stenosis in the proximal segment of the right coronary artery (Figure 1A), with no significant angiographic stenosis in the remaining arteries. (revespcardiol.org)
  • A: severe stenosis in the proximal segment of the right coronary artery. (revespcardiol.org)
  • The coronary angiograms show the left main coronary artery with severe ostial stenosis and left anterior descending artery (LAD) with a diffuse lesion in the mid segment and right coronary artery from the midportion of the LAD. (wjgnet.com)
  • Coronary artery disease (CAD) and severe aortic valve stenosis frequently coexist. (springer.com)
  • Chronic stable angina is a clinical expression of myocardial ischemia associated with fixed atherosclerotic coronary stenosis, which prevents the adaptation of coronary circulation resulting in an increased oxygen requirement. (pubmedcentralcanada.ca)
  • Objective To evaluate the intermediate-term outcomes of patients with unprotected left main coronary artery stenosis who were treated with percutaneous coronary intervention in Hong Kong. (hkmj.org)
  • Treatment of progressive coronary stenosis or acute thrombotic occlusion by means of percutaneous coronary intervention (PCI) with balloon dilatation and stent placement aims to reduce the risk of myocardial ischemia or necrosis by restoring coronary flow. (minervamedica.it)
  • The primary outcome was presence of obstructive CAD, defined as ≥ 1 coronary artery or bypass graft with ≥ 70% stenosis. (ovid.com)
  • The coronary angiogram revealed a 50% stenosis of the mid-left anterior descending artery and a total occlusion of the RCA (Figure 1). (invasivecardiology.com)
  • At that time, emergent cardiac catheterization demonstrated an occlusive lesion in the mid portion of his RCA and severe stenosis of both the high lateral branch and left circumflex (LCX) artery. (biomedcentral.com)
  • Left main coronary artery stenosis: a meta-analysis of drug-eluting stents versus coronary artery bypass grafting. (qxmd.com)
  • Patients were eligible if 50 years or older, with type 2 diabetes, receiving anti-hyperglycaemic drugs for at least 6 months, with stable coronary artery disease, and one of three other mutually non-exclusive criteria: a history of previous PCI or of coronary artery bypass grafting, or documentation of angiographic stenosis of 50% or more in at least one coronary artery. (elsevier.com)
  • She subsequently developed aortic stenosis and left main coronary artery stenosis. (nyp.org)
  • Coronary artery disease (CAD) and aortic stenosis often coexist. (hindawi.com)
  • There is considerable overlap in both the pathophysiology and presence of atherosclerotic coronary artery disease (CAD) and calcific aortic stenosis (AS), with concomitant significant CAD observed in up to 50% of individuals presenting with severe AS [ 1 ]. (hindawi.com)
  • We described the case of a 65-year-old man known for dyslipidemia and family history of coronary artery disease who was admitted for non-ST elevation myocardial infarction as a result of a severe stenosis of the left anterior descending (LAD) coronary artery. (imedpub.com)
  • Since the year of 1977, when Andreas Gruentzig first successfully performed percutaneous coronary balloon angioplasty to a patient with left anterior descending artery (LAD) stenosis (1), percutaneous coronary interventions (PCI's) have come to a practice. (hvt-journal.com)
  • Coronary flow might be limited by the combination of epicardial stenosis, diffuse coronary artery disease, and microvascular resistance (MR). Therefore, not only epicardial stenosis modification but also improvement of microcirculatory resistance will benefit from coronary flow increase brought about by percutaneous coronary intervention (PCI). (physiology.org)
  • Of increasing importance, endothelial dysfunction is now also recognized as a cause of angina in the absence of epicardial coronary artery stenosis or spasm (see Syndrome X ). (merckmanuals.com)
  • In this study, we assessed whether post-PCI CMVD may predict clinical outcome in patients undergoing successful elective PCI of an isolated stenosis of the left anterior descending (LAD) coronary artery. (unicatt.it)
  • Conclusions: Our data suggest that, in patients with successful PCI of LAD coronary artery stenosis, lower CBF response to the endothelium-dependent vasodilator stimulus CPT is associated with long-term recurrence of restenosis. (unicatt.it)
  • In some cases especially RHD with severe mitral stenosis (MS), thrombus that develop in left atrium may embolize in one of the coronary arteries, leading to acute coronary syndrome. (who.int)
  • Coronary artery bypass graft surgery is arguably the most intensively studied surgical procedure, and percutaneous coronary intervention (PCI) has been subjected to more randomized clinical trials than any other interventional procedure. (dovepress.com)
  • Comparative effectiveness of multivessel coronary artery bypass graft surgery and multivessel percutaneous coronary intervention. (nih.gov)
  • The Great Revascularization Strategy Debate: Coronary Artery Bypass Graft or Percutaneous Coronary Intervention? (ajmc.com)
  • The 2 primary methods of revascularization are coronary artery bypass graft and percutaneous coronary intervention, but the preferred strategy for use in these patients requires clarification due to risk. (ajmc.com)
  • Coronary artery bypass graft versus percutaneous coronary intervention in acute heart failure. (ajmc.com)
  • Our attention was especially attracted to the very important and didactic conclusion that compared with native coronary PCI, bypass graft PCI is independently associated with higher in-hospital mortality, which relates to our research that soon will be published by Xanthopoulou et al. (onlinejacc.org)
  • TY - JOUR T1 - Risk of restenosis and health status outcomes for patients undergoing percutaneous coronary intervention versus coronary artery bypass graft surgery. (unboundmedicine.com)
  • Clinical Trials and Graft Patency Data in Coronary Artery Surgery�A 30-Year Perspective. (ebscohost.com)
  • Number ofacute myocardial infarction hospitalisations with percutaneous coronary and/or coronary artery bypass graft interventions per 100,000 people aged 35-84 years, age and sex standardised. (aihw.gov.au)
  • Blood flow from the GEA graft and native RCA supplied the proximal lesion of the PD artery. (biomedcentral.com)
  • In fully adjusted models, independent correlates of CAC were age, hypertension, hypercholesterolemia, smoking, previous coronary artery bypass graft surgery, and worse left ventricular and renal function. (elsevier.com)
  • He underwent excision of the large proximal LAD pseudoaneurysm, excision of the previous LAD stent, ligation of proximal LAD, and coronary artery bypass grafting with LIMA-LAD graft. (openaccessjournals.com)
  • Clinical, angiographic, and procedural characteristics as well as in-hospital and long-term outcomes were measured in patients grouped into 4 eras depending on the dominant interventional strategy of that time: percutaneous transluminal coronary angioplasty, early stent, bare-metal stent, and drug-eluting stent. (onlinejacc.org)
  • We describe 2 identical twins diagnosed with unstable angina, in both cases with right coronary artery disease, within an interval of 6 months, and both treated percutaneously with placement of a coronary stent. (revespcardiol.org)
  • An ad hoc percutaneous coronary intervention was performed, with direct implantation of a 4x28-mm Taxus stent (Boston Sci), with good angiographic results and no complications (Figure 1B). (revespcardiol.org)
  • As occurred with the patient's brother, the right coronary artery was treated, in this case with a 4x15-mm bare metal stent (Driver, Medtronic Inc.) (Figure 2B). (revespcardiol.org)
  • The images show excellent stent expansion and no dissection in the left main coronary artery ostia, the mid segment of left anterior descending artery, and right coronary artery with thrombolysis in myocardial infarction grade 3 flow. (wjgnet.com)
  • Such studies have shown that besides the physical trauma induced by a balloon or a stent also the specific histomorphological and biological properties of the treated coronary plaques play an important role in the risk of PCI related vascular complications. (minervamedica.it)
  • Both in case of BMS and DES emerging evidence from recent histopathological studies on coronary resected stents shows that the outcome of PCI can be influenced by the occurrence of in stent neo- atherosclerosis, in DES more frequent than in BMS, which in turn may stimulate both thrombosis and restenosis on the very long term. (minervamedica.it)
  • Optical flow ratio (OFR) is a recently developed method for functional assessment of coronary artery disease based on computational fluid dynamics of vascular anatomical data from intravascular optical coherence tomography (OCT). The purpose of this study was to investigate the relationship between OFR and fractional flow reserve (FFR) in stent-treated arteries immediately after percutaneous coronary intervention (PCI). (go.jp)
  • The OFR and FFR were measured in 103 coronary arteries immediately after successful PCI with a stent. (go.jp)
  • OFR showed a high correlation and good agreement with FFR in stent-treated arteries immediately after PCI. (go.jp)
  • With improvements in medical therapy as well as innovative stent technology there has been a growing interest in the role of percutaneous coronary intervention (PCI) in patients with LMCAD ( 4 - 7 ). (amegroups.com)
  • The objective of this study is to evaluate the safety and effectiveness of the clinical and technical performance of the CorPath® 200 System in the delivery and manipulation of coronary guidewires and stent/balloon systems for use in percutaneous coronary interventions (PCI). (clinicaltrials.gov)
  • This approach combines minimally invasive robotic bypass off-pump, with the remaining arteries managed with stent placement. (nyp.org)
  • A 62-year-old Bangladeshi male smoker with past medical history of hypertension, type II diabetes mellitus suffered non-ST elevation myocardial infarctions (NSTEMIs) in Apr and Oct 2017 for which he underwent drug-eluting stent (DES) deployment to the proximal left anterior descending artery (LAD) and successful angioplasty of an occluded LAD from late stent thrombosis followed by deployment of a second stent respectively. (openaccessjournals.com)
  • AIMS: The aim of this study was to assess the occurrence of distal embolization and to quantify the amount of embolic material captured during stent implantation in native coronary arteries, as compared with saphenous vein grafts (SVG) in patients at different time periods after an acute coronary syndrome. (euc.ac.cy)
  • PATIENTS AND METHODS: In all, 104 patients presenting with unstable or stable angina underwent percutaneous coronary intervention (PCI) in 107 vessels and stent implantation in 112 lesions, 53 % of which were in SVG. (euc.ac.cy)
  • Following multidisciplinary discussion within the Heart Team, a percutaneous coronary intervention (PCI) with a drug eluting stent of LIMA was performed with a good angiographic result and normalization of the flow. (imedpub.com)
  • Percutaneous coronary intervention, or PCI, is a set of minimally invasive procedures that uses a catheter to place a small device such as a special balloon or stent within a blocked blood vessel in order to open the blockage and re-establish blood flow. (bostonscientific.com)
  • Once the stent is placed into the coronary artery, it expands with the inflation of a balloon catheter. (bostonscientific.com)
  • The stent is left in the artery to keep it open and helps restore blood flow to the heart. (bostonscientific.com)
  • Depending on your needs, your doctor may use a small metal stent alone or choose one that is coated with a medicine that helps keep the artery from getting narrow or blocked again. (bostonscientific.com)
  • During percutaneous coronary intervention (PCI), CACs are an impediment to crossing the lesion with standard devices and to dilation with a standard balloon, which often results in stent underexpansion, and procedural complications such as slow flow/no reflow, dissection, and perforation. (medscape.com)
  • [ 4 , 6-8 ] In a large patient-level pooled analysis of acute coronary syndrome patients treated with stent, moderate or severe calcification was associated with a 62% higher risk of stent thrombosis and a 44% higher risk of target lesion failure than in non- or mildly calcified lesions. (medscape.com)
  • BACKGROUND: The Occluded Artery Trial (OAT) was a 2,201-patient randomized clinical trial comparing routine stent-based percutaneous coronary intervention (PCI) versus optimal medical therapy alone in stable myocardial infarction (MI) survivors with persistent infarct-related artery occlusion identified day 3 to 28 post MI. (unibas.ch)
  • Predicate data from the Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) clinical trial and other clinical trials have suggested that the LMCA may be ideally suited to maximize the potential relative benefits of PCI (less invasiveness, ideally suited for larger vessels with more focal disease) while mitigating its relative disadvantages (restenosis and stent thrombosis, especially when tackling diffuse disease). (jamanetwork.com)
  • 75%) of the LAD coronary artery who underwent successful PCI with stent implantation. (unicatt.it)
  • A stent (circular, stainless steel device which resembles the spring in a ballpoint pen) may be inserted into the artery to keep it open. (everything2.com)
  • This lesion was treated with stent placement in the left anterior descending coronary artery, as observed in the right panel. (medscape.com)
  • We report the results of a hybrid procedure performed on the same day, combining PCI of the right coronary artery and internal mammary artery bypass grafting of the left coronary artery, for the treatment of diffuse extensive lesions. (biomedsearch.com)
  • METHODS AND RESULTS: Since January 2000, 70 patients (53 male, mean age 68.5 +/- 10 years) underwent this hybrid revascularization combining primary right coronary artery PCI and, within the next 16 h, left coronary artery grafting with left and/or right internal mammary artery. (biomedsearch.com)
  • A: severe lesion in the middle right coronary artery. (revespcardiol.org)
  • We describe a case of right coronary artery (RCA) perforation during a recanalization attempt of a chronic total occlusion complicated by impending tamponade and treated with transcatheter injection of polyvinyl alcohol (PVA) foam embolization particles. (invasivecardiology.com)
  • Because of the unusual anatomy of an anomalous origin of the right coronary artery from the left sinus of Valsalva, selective cannulation of the guiding catheter in percutaneous coronary intervention for these cases is always challenging. (biomedcentral.com)
  • We found a subtotal occlusive lesion in the mid-portion of his right coronary artery that originated from the left sinus of Valsalva. (biomedcentral.com)
  • On the previous percutaneous coronary intervention, we failed to cannulate the guiding catheter to the anomalous orifice of the right coronary artery. (biomedcentral.com)
  • A 6Fr GuideLiner catheter was introduced into the right coronary artery by anchoring it coaxially with a semi-compliant balloon catheter. (biomedcentral.com)
  • An anomalous origin of the right coronary artery (RCA) from the left sinus of Valsalva is uncommon but occasionally noted in association with potentially serious sequelae such as sudden death. (biomedcentral.com)
  • Early PCI, during a 2-week period after the last ischemic episode, was associated with larger embolic load, especially in the right coronary artery. (euc.ac.cy)
  • Stenting of right coronary artery Figure 2. (hvt-journal.com)
  • Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual pa. (nih.gov)
  • Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials. (nih.gov)
  • Factors affecting regression of mitral regurgitation following isolated coronary artery bypass surgery. (ebscohost.com)
  • The article focuses on a study that explores percutaneous coronary intervention (PCI) instead of bypass surgery for high risk patient. (ebscohost.com)
  • Abstract: Many approaches for minimally invasive coronary bypass surgery are available and to further decrease the invasiveness, coronary artery bypass grafting has been performed under high thoracic epidural anesthesia without endotracheal intubation in the last years. (ebscohost.com)
  • Rates of PCI or coronary artery bypass surgery were 12.7% and 10.6%, respectively (p = 0.30). (onlinejacc.org)
  • Coronary artery perforation is a rare but potentially catastrophic complication of PCI.1-4 It has been reported to occur in 0.1% to 3.0% of lesions treated with various intervention techniques and accounts for 20% of referrals for emergency bypass surgery. (invasivecardiology.com)
  • No specific guidelines exist concerning the appropriate treatment (medical therapy, intracoronary stents, coronary bypass surgery) or the optimal type of stents in otherwise atheroma-free vessels. (octnews.org)
  • Prolonged effectiveness of coronary artery bypass surgery versus drug-eluting stents in diabetics with multi-vessel disease: an updated systematic review and meta-analysis. (qxmd.com)
  • Complex PCI is defined as a PCI treatment developed to treat people who have complex blockages, complex arteries or those for whom bypass surgery is not recommended. (bostonscientific.com)
  • Emergency coronary artery bypass surgery was carried out. (hvt-journal.com)
  • Comparison of coronary bypass surgery with angioplasty in patients with multivessel disease. (cardiachealth.org)
  • Previous reports cite an incidence of between 0.2-0.6% 1- 6 and while some of these series were reported during the era of balloon angioplasty alone, more recent studies have referred to intervention using newer devices including stents and rotational and directional atherectomy. (bmj.com)
  • The Changing Morality of Myocardial Revascularization: Coronary Artery Bypass and Angioplasty. (ebscohost.com)
  • Discusses the abstract of the article 'The Changing Mortality of Myocardial Revascularization: Coronary Artery Bypass and Angioplasty,' by Keith S. Naunheim et al. (ebscohost.com)
  • A coronary angioplasty is a type of minimally invasive procedure to treat CAD. (bostonscientific.com)
  • However, major limitations of balloon angioplasty of coronary arteries were complications such as restenosis and abrupt vessel closure (2). (hvt-journal.com)
  • This procedure was formally called angioplasty or percutaneous transluminal coronary angioplasty. (everything2.com)
  • An interventional cardiologist is a heart doctor who specializes in minimally invasive percutaneous coronary intervention (PCI) procedures, like stenting and angioplasty. (bostonscientific.com)
  • Objectives We sought to determine the characteristics, outcomes, and temporal trends among patients undergoing percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) from a single-center registry. (onlinejacc.org)
  • These have resulted in an improvement in outcomes and the ability to treat sicker patients as well as those with complex coronary morphology ( 1 ). (onlinejacc.org)
  • Prevalence, predictors, and in-hospital outcomes of non-infarct artery intervention during primary percutaneous coronary intervention for ST-segmen. (nih.gov)
  • Prevalence, predictors, and in-hospital outcomes of non-infarct artery intervention during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (from the National Cardiovascular Data Registry). (nih.gov)
  • Long-term outcomes of percutaneous coronary intervention in grafts and native vessels in coronary artery bypass grafting patients with diabetes mellitus. (medworm.com)
  • They compare outcomes between those patients on optimal medical therapy (OMT) and non-optimal medical therapy following revascularization for complex coronary artery disease (CAD). (ctsnet.org)
  • This study demonstrated that performing percutaneous coronary intervention (PCI) for unprotected left main coronary artery (ULMCA) disease in this Chinese cohort was safe and feasible in selected patients with high procedural success and good intermediate-term outcomes. (hkmj.org)
  • However, it is unclear if revascularization with percutaneous coronary intervention (PCI) to relieve ischemia improves outcomes compared with medical therapy (MT). (nih.gov)
  • Taggart, David P. / Stroke after coronary artery bypass grafting and percutaneous coronary intervention : Incidence, pathogenesis, and outcomes . (elsevier.com)
  • Early infarct related artery (IRA) patency and prompt myocardial reperfusion are crucial for improving clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) [ 1 ], primary percutaneous coronary intervention (PPCI) is the current therapy of choice to achieve IRA patency. (biomedcentral.com)
  • Long-term outcomes of percutaneous coronary intervention for unprotected left main coronary artery disease. (nihr.ac.uk)
  • Comparison on the long-term outcomes post percutaneous coronary intervention or coronary artery bypass grafting for bifurcation lesions in unprotected left main coronary artery]. (qxmd.com)
  • Long-term outcomes after stenting versus coronary artery bypass grafting for unprotected left main coronary artery disease: 10-year results of bare-metal stents and 5-year results of drug-eluting stents from the ASAN-MAIN (ASAN Medical Center-Left MAIN Revascularization) Registry. (qxmd.com)
  • Methods: The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, double-blinded, placebo-controlled trial, done in 1315 sites in 42 countries. (elsevier.com)
  • Elderly patients with unstable coronary artery disease (CAD) have better outcomes with coronary revascularization than conservative treatment. (opencardiovascularmedicinejournal.com)
  • Patients Patients with unprotected left main coronary artery disease undergoing stenting with bare-metal stents or drug-eluting stents between January 2008 and September 2011. (hkmj.org)
  • Compared with bare-metal stents, drug-eluting stents were associated with a lower need for repeating revascularisation without increasing the risk of death or myocardial infarction in patients with unprotected left main coronary artery disease. (hkmj.org)
  • With the introduction of drug-eluting stents (DES), the percentage of patients with multivessel coronary artery disease (CAD) in whom percutaneous coronary intervention (PCI) is performed, has increased ( 1 ). (onlinejacc.org)
  • And we successfully deployed two drug-eluting stents by crossing over the posterior-descending artery. (biomedcentral.com)
  • OBJECTIVES: The aim of this study was to investigate the clinical correlates and prognostic impact of coronary artery calcification (CAC) in women undergoing percutaneous coronary intervention with drug-eluting stents (DES). (elsevier.com)
  • While drug-eluting stents are the current standard for percutaneous coronary intervention, these stents necessitate longer durations of dual antiplatelet therapy (DAPT), potentially increasing bleeding in patients predisposed to these complications. (nyp.org)
  • A patient with unstable angina and two-vessel disease underwent drug eluting stents implantation in proximal left anterior descending artery and distal left circumflex artery. (hvt-journal.com)
  • Newer alternative modalities such as hybrid coronary revascularization (HCR) are gaining prominence, this approach utilizes left internal mammary artery (LIMA) to the left anterior descending artery (LAD) and drug eluting stents for non-LAD lesions. (ismics.org)
  • With the improvement in percutaneous coronary intervention (PCI) techniques using drug eluting-stents, this became an attractive option in elderly. (opencardiovascularmedicinejournal.com)
  • Relation of multivessel primary percutaneous coronary intervention for ST-elevation myocardial infarction to outcome and/or non-infarct artery intervention of a chronic total occlusion. (nih.gov)
  • Spontaneous reperfusion (SR) and early infarct related artery (IRA) patency before primary percutaneous coronary intervention (PPCI) might bring extra benefit for patients with ST-segment elevation myocardial infarction (STEMI). (biomedcentral.com)
  • 357 patients who received successful primary percutaneous coronary intervention from January 2008 to March 2011 in Peking University Third Hospital were included in this study. (hindawi.com)
  • Evidence from clinical studies revealed that 600 mg loading dose of clopidogrel compared with 300 mg resulted in decreased 30-day ischemic adverse event and death rates in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) [ 7 , 8 ]. (hindawi.com)
  • While prompt surgical intervention may be life saving, expertise in the use of covered stents may provide a valuable rescue option for this serious complication. (bmj.com)
  • Randomized clinical trials of PCI and MT vs MT alone for stable coronary artery disease in which stents and statins were used in more than 50% of patients. (nih.gov)
  • Rate of complications was significantly reduced with the introduction of coronary stents (3). (hvt-journal.com)
  • Coronary stents act as scaffolds to prevent elastic recoil and to prevent the spreading of intimal dissection (4), which frequently occurs after balloon inflation. (hvt-journal.com)
  • The SYNTAX score (SS) is an angiographic tool to help cardiologists, interventionalists and surgeons grade coronary artery lesion complexity. (benthamopen.com)
  • Study lesion is a single de novo native coronary artery lesion. (clinicaltrials.gov)
  • Coronary angiogram showed occluded proximal left anterior descending (LAD) coronary artery including the previously stented segment, a discrete 75% ostial first obtuse marginal (OM) lesion, and extravasation of contrast into a large pseudoaneurysm. (openaccessjournals.com)
  • We are still in the middle of a long and rocky road before we master the treatment of calcified lesion(s)-one of the last remaining challenges in coronary intervention. (medscape.com)
  • This trial randomized 2,201 stable patients with infarct-related artery total occlusion >24 hours after myocardial infarction to PCI or medical therapy. (acc.org)
  • Furthermore, the occlusion rate at the access point is considered to be higher in the distal radial artery than in the forearm radial artery access, because of its relatively small caliber. (cathlabdigest.com)
  • To avoid radial artery occlusion, patent hemostasis is achieved using the Barbeau test, in which the ulnar artery is occluded during radial artery compression. (cathlabdigest.com)
  • The initial size of the radial artery was 2.3 mm, and it was 2.5 mm 24 hours after PCI without radial occlusion. (cathlabdigest.com)
  • For conventional radial access, patent hemostasis with the Barbeau test is recommended to prevent the radial artery occlusion. (cathlabdigest.com)
  • Therefore, patency of the radial artery can be evaluated by occlusion of the ulnar artery. (cathlabdigest.com)
  • Therefore, during evaluation of patent hemostasis in the access site by occlusion of the ulnar artery, the superficial palmar arch artery can provide blood to the hand and may cause false positive results. (cathlabdigest.com)
  • detection of the blood flow in the current study is considered a contributing factor for the prevention of radial artery occlusion. (cathlabdigest.com)
  • The hemostatic method described in the current study is feasible and may contribute to preventing radial artery occlusion by detecting blood flow during compression with sonography. (cathlabdigest.com)
  • An ad hoc PCI was attempted to recanalize the proximal RCA occlusion via the right femoral artery. (invasivecardiology.com)
  • Despite the initial success of the repeated intervention, total occlusion of left main coronary artery occurred with unsuccessful reopening in catheterization laboratory. (hvt-journal.com)
  • however, the actual trauma of complete coronary artery occlusion is the result of a ruptured plaque deposit which in turn triggers the immune response . (everything2.com)
  • Platelets and other immune products form a clot which is actually the cause of artery occlusion. (everything2.com)
  • abstract = "Coronary artery (CA) aneurysms are serious complications of Kawasaki disease (KD) responsible for ischemic events. (elsevier.com)
  • Despite the increasing role of coronary revascularization in patients with acute coronary syndromes, stable CAD remains one of the most common indications for referral to the cardiac catheterization laboratory ( 2 ). (onlinejacc.org)
  • Excluding patients without adequate data, we retrospectively compared clinical background, coronary risk factors, angiographic findings, acute results of primary PCI and in-hospital prognosis between patients undergoing primary PCI in hospitals without on-site cardiac surgery (without surgery group, n=792) and those in hospitals with (with surgery group, n=993). (go.jp)
  • Conclusions: In this observational study of adult with cardiac arrest undergoing coronary angiogram, gender was not independently predictive of obstructive CAD or mortality. (ovid.com)
  • The European registry of cardiac catheter interventions 1996. (springermedizin.at)
  • The interventional cardiologists and cardiac surgeons at NewYork-Presbyterian offer the most advanced percutaneous coronary interventions and coronary bypass programs in the world. (nyp.org)
  • Cardiac catheterization checks your arteries for flow and blockage. (familydoctor.org)
  • Cardiac computed tomography (CT) scan produces an image of your heart and arteries. (familydoctor.org)
  • Cardiac catheterization of the left or the right heart can be used to do various tests, and it also can be used to determine appropriate therapeutic interventions. (merckmanuals.com)
  • Clinical presentations include silent ischemia, angina pectoris , acute coronary syndromes ( unstable angina , myocardial infarction ), and sudden cardiac death . (merckmanuals.com)
  • The Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Sugery (SYNTAX) scores were measured to assess the coronary vasculature. (inpharmd.com)
  • A cardiac interventionalist enters the body through an artery either of the arm or leg (most commonly, through the right femoral artery) and moves through the circulatory system (generally straight up the abdominal aorta and into the coronary arteries). (everything2.com)
  • The SYNTAX (Synergy between PCI with taxus and cardiac surgery) trail, conducted in United States and several countries in Europe, involved 1800 patients with previously untreated triple vessel disease or left main coronary artery disease. (emedicinelive.com)
  • Of the 11 centres contributing data, six were metropolitan centres, five had provision for 24-hour percutaneous coronary intervention (PCI) and four had onsite cardiac surgery. (mja.com.au)
  • This strategy optimizes revascularization when patients are unstable or present very severe coronary lesions, which requiring rapid treatment and are not ideally suitable for PCI management alone. (biomedsearch.com)
  • 1 Coronary heart disease affects 30%-60% of patients with ESRD, and it usually involves multiple vessels, proximal lesions, heavy calcifications, or diffuse disease. (asnjournals.org)
  • The optimal revascularization strategy in patients with acute coronary syndrome (ACS) and proximal left anterior descending (pLAD) coronary artery lesions is not well defined. (unboundmedicine.com)
  • 1,2,6 It has also been shown to be more frequent in the left circumflex and right coronary arteries, in long, and eccentric lesions. (invasivecardiology.com)
  • GuideLiner is a monorail-type "child" support catheter that facilitates coaxial guiding catheter engagement and an appropriate back-up force, achieving successful device delivery to target lesions in this kind of complex percutaneous coronary intervention. (biomedcentral.com)
  • There were no visible lesions in the left main coronary artery (LMCA). (hvt-journal.com)
  • Spontaneous coronary artery dissection (SCAD) is a rare, life-threatening condition that usually manifests as an acute myocardial infarction. (biomedsearch.com)
  • Percutaneous Coronary Intervention in Spontaneous Coronary Artery Dissection: Role of Intravascular Ultrasound. (biomedsearch.com)
  • Spontaneous coronary artery dissection (SCAD) is an infrequent cause of acute coronary syndromes but is represented disproportionately in young female patients. (octnews.org)
  • Spontaneous Coronary Artery Dissection (SCAD) is an unusual but important cause of acute coronary syndromes. (ircrj.com)
  • We describe a case of guiding catheter-induced dissection of left main coronary artery and ascending aorta. (hvt-journal.com)
  • Six hours after the procedure of acute occlusive dissection of left main coronary artery with spreading to ascending aorta developed, it was required to do stenting of the left anterior descending and left main coronary arteries and balloon dilatation of left circumflex artery. (hvt-journal.com)
  • In this report, we describe a case of dissection of left main coronary artery and aortic root after "routine" PCI. (hvt-journal.com)
  • Spontaneous coronary artery dissection (SCAD) is a non-iatrogenic non-traumatic separation of the coronary arterial wall. (wikidoc.org)
  • On June 22, 2020, the first case of COVID-19 with spontaneous coronary artery dissection was reported. (wikidoc.org)
  • Coronary artery dissection may be related to intraplaque hemorrhage resulting in an intra-adventitial hematoma , which can spread longitudinally along the coronary artery, dissecting the tunicae. (wikidoc.org)
  • This can lead to the development of sudden coronary artery dissection in a susceptible patient with underlying cardiovascular disease . (wikidoc.org)
  • At present the pathophysiology of non-atherosclerotic spontaneous coronary artery dissection (NA-SCAD) continues to be poorly understood due to the rarity of this condition and its heterogeneous pathology. (wikidoc.org)
  • To read more about the pathophysiology of Spontaneous Coronary Artery Dissection , Click here . (wikidoc.org)
  • COVID‐19 associated spontaneous coronary artery dissection is caused by Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS‐CoV‐2 ). (wikidoc.org)
  • For other causes of spontaneous coronary artery dissection, Click here . (wikidoc.org)
  • To examine the clinical outcome of percutaneous coronary intervention where the procedure was complicated by vessel perforation. (bmj.com)
  • Surgical and percutaneous revascularization strategies have different strengths and weaknesses, and neither strategy is superior in all patients, clinical presentations, or anatomical subgroups. (dovepress.com)
  • The best revascularization strategy for an individual patient must take into account clinical presentation, comorbidities, the extent and complexity of the coronary artery disease, and data from trials reflecting contemporary practice. (dovepress.com)
  • The relative merits of medical therapy versus percutaneous coronary intervention (PCI) for stable CAD have been investigated in numerous clinical trials ( 3-6 ). (onlinejacc.org)
  • 2 - 4 Because of the high burden and poor prognosis of coronary disease in this patient population, optimal management of coronary heart disease-particularly the choice of revascularization modality-is a critical clinical issue. (asnjournals.org)
  • The authors concluded that late PCI (more than 24 hours) of a totally occluded infarct-related artery is not associated with any clinical benefit. (acc.org)
  • This follow-up analysis from OAT clearly establishes the lack of clinical benefit of routine PCI for patients with an occluded infarct-related artery late after a myocardial infarction. (acc.org)
  • Acute coronary syndromes (ACS) represent the clinical manifestations of sudden flow limiting coronary artery disease leading to acute myocardial ischemia or necrosis. (minervamedica.it)
  • BACKGROUND: The clinical correlates and the prognostic significance of CAC in women undergoing percutaneous coronary intervention with DES remain unclear. (elsevier.com)
  • Such coronary microvascular impairment, indicated by increased microvascular resistance, may contribute to the pathogenesis of myocardial ischemia and is an independent predictor of poor clinical outcome in patients with cardiovascular disease ( 13 , 20 ). (physiology.org)
  • It can be argued that severe left main coronary artery (LMCA) disease represents the only anatomic subtype of coronary artery disease for which there is clear and unequivocal prognostic evidence in favor of coronary revascularization across the spectrum of clinical presentation-from stable ischemic heart disease to acute coronary syndrome. (jamanetwork.com)
  • 2 Randomised clinical trials have demonstrated the mortality benefit of pharmacological and procedural interventions for this condition, and cross-sectional studies have shown that better adherence to these therapies is effective in reducing mortality and morbidity. (mja.com.au)
  • Then the sonography probe was applied at the balloon surface, and the radial artery was detected. (cathlabdigest.com)
  • To report on the feasibility and technical differences between coronary procedures performed before and after TAVR with the balloon-expandable Edwards-SAPIEN or the SAPIEN XT valves. (hindawi.com)
  • Transcatheter heart valves (THV) can be broadly divided into balloon-, self- or mechanically expanding in nature [ 4 ], with each prosthetic class possessing unique characteristics pertaining to their design, material, annuloaortic orientation, and anatomic relation to the native coronary tree. (hindawi.com)
  • Despite various reports describing technical differences and potential challenges of CA and PCI in TAVR recipients [ 5 ], the nuances and technicalities for catheterizing and effectively accessing the native epicardial coronary vasculature in the presence of in situ THV are yet to be systematically reported in the presence of a balloon-expandable valve system. (hindawi.com)
  • A balloon-like catheter is inflated which reopens the artery. (everything2.com)
  • Patient was hemodynamically unstable and underwent percutaneous balloon mitral valvotomy (PBMV) and percutaneous coronary intervention (PCI) simultaneously. (who.int)
  • The demand for performing post-TAVR coronary angiograms (CAs) and percutaneous coronary interventions (PCIs) will thus increase, posing new technical challenges. (hindawi.com)
  • Neither CAs‐nor PCIs‐performed after valve implantation revealed significant differences regarding arterial access site, catheter diameter, number of diagnostic or guiding catheters used, procedural duration, fluoroscopy time, or achievement of selective coronary injection. (hindawi.com)
  • Background: Several patients with successful percutaneous coronary interventions (PCIs) show evidence of coronary microvascular dysfunction (CMVD), which can be responsible for persistent positivity of electrocardiographic exercise stress test (EST). (unicatt.it)
  • 7 On the other hand, as calcified, tortuous, and occluded vessels are increasingly treated by percutaneous means, vessel perforation is likely to persist. (bmj.com)
  • Disease progression to the native vessels (NV) or failure of grafts due to similar mechanisms with NV atherosclerosis usually lead to repeat coronary revascularizations ( 5 ). (onlinejacc.org)
  • What is the long-term impact of percutaneous coronary intervention (PCI) performed on totally occluded vessels in patients with recent myocardial infarction (days 3-28)? (acc.org)
  • Coronary atherosclerosis is often irregularly distributed in different vessels but typically occurs at points of turbulence (eg, vessel bifurcations). (merckmanuals.com)
  • Percutaneous coronary intervention (PCI) is indicated for treating partially and completely occluded coronary vessels. (inpharmd.com)
  • As the range of equipment available to the interventional cardiologist evolves, together with necessary operator expertise, more complex coronary anatomy is being treated percutaneously. (bmj.com)
  • Recent advancements in PCI have given doctors tools and techniques to be able to successfully treat more people considered to have complex coronary artery disease, or high risk, than ever before. (bostonscientific.com)
  • Higher scores indicated a more complex coronary structure. (inpharmd.com)
  • Background: Remodeling of the radial artery (RA) after transradial percutaneous coronary intervention (TRI) is under studied. (visualsonics.com)
  • Radial artery perforation is one of the major complications of transradial percutaneous coronary intervention (PCI). (bvsalud.org)
  • Objectives To assess the perceptions of patients with stable coronary artery disease of the urgency and benefits of elective percutaneous coronary intervention and to examine how they vary across centers and by providers. (bmj.com)
  • Participants 991 patients with stable coronary artery disease undergoing elective percutaneous coronary intervention. (bmj.com)
  • Although elective percutaneous coronary intervention can alleviate the symptoms of angina in patients with stable coronary artery disease, numerous studies and meta-analyses have shown that it does not prevent myocardial infarction or death, as compared with optimal medical treatment alone. (bmj.com)
  • Patients' with a better understanding about treatments may be more involved in shared decision making, thus being more likely to receive care that is aligned with their goals and ensuring that practice variations in treatment for stable coronary artery disease result from patients' rather than from physicians' preferences. (bmj.com)
  • 6 7 8 9 10 11 For patients to meaningfully participate in decision making about treatment for their stable coronary artery disease, a sound understanding of the benefits, risks, and alternatives of elective percutaneous coronary intervention is essential. (bmj.com)
  • Who should have percutaneous coronary intervention in stable coronary artery disease? (bmj.com)
  • Importantly, the pathological substrate of the treated coronary artery segment in patients with ACS differs significantly from coronary artery segments in patients with stable coronary artery disease. (minervamedica.it)
  • Myocardial ischemia in patients with stable coronary artery disease (CAD) has been repeatedly associated with impaired survival. (nih.gov)
  • Background: Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. (elsevier.com)
  • Interpretation: In patients with diabetes, stable coronary artery disease, and previous PCI, ticagrelor added to aspirin reduced cardiovascular death, myocardial infarction, and stroke, although with increased major bleeding. (elsevier.com)
  • Early CAC is associated with a risk of acute coronary syndrome, whereas advanced CAC is a passive, degenerative, and stable phenomenon, characteristic of the ageing process. (medscape.com)
  • Maier W, Windecker S, Lablanche JM, Mühlberger V, Wijns W, Meier B (on behalf of the working group Coronary Circulation of the European Society of Cardiology). (springermedizin.at)
  • Rupture exposes collagen and other thrombogenic material, which activate platelets and the coagulation cascade, resulting in an acute thrombus, which interrupts coronary blood flow and causes some degree of myocardial ischemia. (merckmanuals.com)
  • A 78-year-old man with effort angina underwent percutaneous coronary intervention (PCI) of the left anterior descending artery and the right distal radial artery using a 6 French (Fr) Glidesheath Slender introducer sheath (Terumo). (cathlabdigest.com)
  • There are anatomical differences between the forearm radial artery and distal radial artery. (cathlabdigest.com)
  • However, in the distal part of the wrist, there are two palmar arch arteries originating from the forearm radial artery, i.e., the superficial and deep palmar arch arteries. (cathlabdigest.com)
  • Our case highlights the challenges in performing successful percutaneous coronary intervention (PCI) in patients with SCAD. (biomedsearch.com)
  • The use of intravascular ultrasound enabled identification of the extent of the disease and served as an important adjunct to successful percutaneous interventional treatment. (ircrj.com)
  • He attended Creighton University School of Medicine and obtained specialty training in internal medicine, cardiology, interventional cardiology and advanced structural interventions at Mayo Clinic. (mayoclinic.org)
  • Pathological examination of atherosclerotic coronary arteries after PCI treatment has been shown to be very helpful in providing insights in this iatrogenic pathology. (minervamedica.it)
  • Coronary atherosclerotic disease is highly prevalent in chronic kidney disease (CKD). (bris.ac.uk)
  • The amount of embolic material seems to be related to the atherosclerotic burden of the vessel and to the early timing of the procedure as related to acute coronary syndrome. (euc.ac.cy)
  • It is the principal cause of coronary artery disease (CAD), in which atherosclerotic changes are present within the walls of the coronary arteries. (medscape.com)
  • Objectives The purpose of this study was to investigate the 2-year outcome of percutaneous coronary intervention (PCI) guided by fractional flow reserve (FFR) in patients with multivessel coronary artery disease (CAD). (onlinejacc.org)
  • Main outcome measures Patients' perceptions of the urgency and benefits of percutaneous coronary intervention, assessed by interview. (bmj.com)
  • JACC: Cardiovascular Interventions , 9 (18), 1890-901. (elsevier.com)
  • 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). (inpharmd.com)
  • Although percutaneous coronary intervention (PCI) is a clearly established approach for coronary artery disease (CAD) but repeat revascularization is a frequent complication. (ismics.org)
  • Conclusion Patients have a poor understanding of the benefits of elective percutaneous coronary intervention, with significant variation across sites. (bmj.com)
  • This study investigates whether hyperemic microvascular resistance (MR) is influenced by elective percutaneous coronary intervention (PCI) by using the index of microcirculatory resistance (IMR). (physiology.org)
  • Patients with End Stage Renal Disease on dialysis have an increased risk for cardiovascular mortality secondary to occlusive coronary artery disease. (ahajournals.org)
  • Coronary artery disease (CAD) involving the LM is associated with high morbidity and mortality. (medworm.com)
  • The article reports on a study in the U.S., which shows that heart surgery or percutaneous revascularisation cuts mortality in patients with severe heart disease by 50 per cent compared with drug therapy alone. (ebscohost.com)
  • Patients with unprotected left main coronary artery (ULMCA) disease treated medically have a three-year mortality rate of approximately 50% ( 3,4 ). (onlinejacc.org)
  • Left Main Revascularization in 2017: Coronary Artery Bypass Grafting or Percutaneous Coronary Intervention? (jamanetwork.com)
  • These THV design differences may thus impact on how coronary interventionalists access the native coronary vasculature. (hindawi.com)
  • In vivo characterisation of coronary plaques with conventional grey-scale intravascular ultrasound: correlation with optical coherence tomography. (octnews.org)
  • The treatment of coronary artery disease, initially by medical and surgical and subsequently using percutaneous interventions, has evolved rapidly over the last 50 years. (ebscohost.com)
  • Because of the unusual anatomy, such as the anomalous position of the RCA ostium within the left aortic sinus, a slit-like orifice or atypical angulation, seen in this type of anomalous RCA, selective cannulation of the guiding catheter in percutaneous coronary intervention (PCI) for these cases is always challenging. (biomedcentral.com)
  • 1,2,6 The management of coronary artery perforation varies with type and the mechanism of perforation. (invasivecardiology.com)
  • Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. (benthamopen.com)
  • No studies have examined impact of gender on presence of obstructive coronary artery disease (CAD) in adults with CA. (ovid.com)
  • Figure 2 Aortography (left anterior oblique view) reveals a blunt right and noncoronary sinus without coronary origin. (wjgnet.com)
  • Conclusions Performing percutaneous coronary intervention for unprotected left main coronary artery disease was safe and feasible in selected patients with high procedural success rate. (hkmj.org)
  • Prespecified subgroup analyses were performed according to the presence or absence of left main coronary artery disease and diabetes, and according to coronary complexity defined by core laboratory SYNTAX score tertiles. (eur.nl)
  • The optimal revascularization technique in patients with left main coronary artery disease (CAD) remains controversial. (biomedcentral.com)
  • The left internal thoracic artery (LITA) was sequentially grafted from the high lateral branch to the LCX posterolateral branch, and the gastroepiploic artery (GEA) was grafted to the right postero-descending (PD) artery. (biomedcentral.com)
  • BACKGROUND: This study evaluates the in-hospital, 30 day and long-term results of stenting for unprotected left main coronary artery disease in our institution. (nihr.ac.uk)
  • This technique brings the mammary artery to the left anterior descending artery without the need for cardiopulmonary bypass or sternotomy. (nyp.org)
  • However, despite the patent anastomosis from left mammary to left anterior descending artery, the patient died. (hvt-journal.com)
  • Echocardiographic Evaluation of Left Ventricular Diastolic Function after Percutaneous Coronary Intervention in Patients with Coronary Artery Disease. (bvsalud.org)
  • Because of the high prevalence of left ventricular diastolic dysfunction in coronary artery disease patients and its probable progression to heart failure , an evaluation of the role of PCI in improving diastolic function is required. (bvsalud.org)
  • Objective of the study was to evaluate the impact of percutaneous coronary intervention on left ventricular diastolic dysfunction by Doppler echocardiography in patients with coronary artery disease . (bvsalud.org)
  • Spontaneous giant coronary artery pseudoaneurysms have been reported following inflammatory disease [ 2 , 3 ] and blunt trauma [ 4 ]. (openaccessjournals.com)