Radiography of the vascular system of the heart muscle after injection of a contrast medium.
The veins and arteries of the HEART.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Radiography of blood vessels after injection of a contrast medium.
Narrowing or constriction of a coronary artery.
The circulation of blood through the CORONARY VESSELS of the HEART.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Radiography of the vascular system of the brain after injection of a contrast medium.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Spasm of the large- or medium-sized coronary arteries.
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Substances used to allow enhanced visualization of tissues.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.
Pressure, burning, or numbness in the chest.
Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
The creation and display of functional images showing where the blood is flowing into the MYOCARDIUM by following over time the distribution of tracers injected into the blood stream.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.
Elements of limited time intervals, contributing to particular results or situations.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Pathologic deposition of calcium salts in tissues.
The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.
Computer systems or networks designed to provide radiographic interpretive information.
Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
Malformations of CORONARY VESSELS, either arteries or veins. Included are anomalous origins of coronary arteries; ARTERIOVENOUS FISTULA; CORONARY ANEURYSM; MYOCARDIAL BRIDGING; and others.
An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Motion pictures of the passage of contrast medium through blood vessels.
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
Triiodo-substituted derivatives of BENZOIC ACID.
Drugs used to cause dilation of the blood vessels.
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes.
The measurement of visualization by radiation of any organ after a radionuclide has been injected into its blood supply. It is used to diagnose heart, liver, lung, and other diseases and to measure the function of those organs, except renography, for which RADIOISOTOPE RENOGRAPHY is available.
A malformation that is characterized by a muscle bridge over a segment of the CORONARY ARTERIES. Systolic contractions of the muscle bridge can lead to narrowing of coronary artery; coronary compression; MYOCARDIAL ISCHEMIA; MYOCARDIAL INFARCTION; and SUDDEN CARDIAC DEATH.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Radiography of the heart and great vessels after injection of a contrast medium.
The hospital unit in which patients with acute cardiac disorders receive intensive care.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
A method of recording heart motion and internal structures by combining ultrasonic imaging with exercise testing (EXERCISE TEST) or pharmacologic stress.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Persistent and reproducible chest discomfort usually precipitated by a physical exertion that dissipates upon cessation of such an activity. The symptoms are manifestations of MYOCARDIAL ISCHEMIA.
A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
The condition of an anatomical structure's being constricted beyond normal dimensions.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Obstruction of flow in biological or prosthetic vascular grafts.
Timing the acquisition of imaging data to specific points in the cardiac cycle to minimize image blurring and other motion artifacts.
The return of a sign, symptom, or disease after a remission.
The hollow, muscular organ that maintains the circulation of the blood.
Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
The degree to which BLOOD VESSELS are not blocked or obstructed.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
A clinical syndrome characterized by the development of CHEST PAIN at rest with concomitant transient ST segment elevation in the ELECTROCARDIOGRAM, but with preserved exercise capacity.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
A low-osmolar, ionic contrast medium used in various radiographic procedures.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.
The study of the heart, its physiology, and its functions.
An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
Lesions formed within the walls of ARTERIES.
Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.
Abnormal communication between two ARTERIES that may result from injury or occur as a congenital abnormality.
Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
The dilatation of the aortic wall behind each of the cusps of the aortic valve.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Disease having a short and relatively severe course.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Endoscopic examination, therapy or surgery performed on the interior of blood vessels.
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.
An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
The main artery of the thigh, a continuation of the external iliac artery.
Delivery of drugs into an artery.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The hospital department responsible for the administration and provision of diagnostic and therapeutic services for the cardiac patient.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A flexible, tubular device that is used to carry fluids into or from a blood vessel, hollow organ, or body cavity.
A characteristic symptom complex.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Pathological conditions involving the HEART including its structural and functional abnormalities.
Congenital vascular anomalies in the brain characterized by direct communication between an artery and a vein without passing through the CAPILLARIES. The locations and size of the shunts determine the symptoms including HEADACHES; SEIZURES; STROKE; INTRACRANIAL HEMORRHAGES; mass effect; and vascular steal effect.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
The vessels carrying blood away from the heart.
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.
The condition of an anatomical structure's being dilated beyond normal dimensions.
The transference of a heart from one human or animal to another.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.
Diagnostic, therapeutic, and investigative procedures prescribed and performed by health professionals, the results of which do not justify the benefits or hazards and costs to the patient.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.
The larger of the two terminal branches of the brachial artery, beginning about one centimeter distal to the bend of the elbow. Like the RADIAL ARTERY, its branches may be divided into three groups corresponding to their locations in the forearm, wrist, and hand.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
ANGINA PECTORIS or angina-like chest pain with a normal coronary arteriogram and positive EXERCISE TEST. The cause of the syndrome is unknown. While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). It is different from METABOLIC SYNDROME X, a syndrome characterized by INSULIN RESISTANCE and HYPERINSULINEMIA, that has increased risk for cardiovascular disease.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Methods of creating machines and devices.
A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.
Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body.
A commonly used x-ray contrast medium. As DIATRIZOATE MEGLUMINE and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
The vein which drains the foot and leg.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Visualization of the heart structure and cardiac blood flow for diagnostic evaluation or to guide cardiac procedures via techniques including ENDOSCOPY (cardiac endoscopy, sometimes refered to as cardioscopy), RADIONUCLIDE IMAGING; MAGNETIC RESONANCE IMAGING; TOMOGRAPHY; or ULTRASONOGRAPHY.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
An abnormal passage between two or more BLOOD VESSELS, between ARTERIES; VEINS; or between an artery and a vein.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.
A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.
Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.
Contractile activity of the MYOCARDIUM.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.
The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.
Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (VENTRICULOGRAPHY, FIRST-PASS).
Diseases that do not exhibit symptoms.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
The flow of BLOOD through or around an organ or region of the body.
Formation and development of a thrombus or blood clot in the blood vessel.
Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.
Motion picture study of successive images appearing on a fluoroscopic screen.
A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.
Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
MYOCARDIAL INFARCTION in which the inferior wall of the heart is involved. It is often caused by occlusion of the right coronary artery.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.

Geographic, demographic, and socioeconomic variations in the investigation and management of coronary heart disease in Scotland. (1/8209)

OBJECTIVE: To determine whether age, sex, level of deprivation, and area of residence affect the likelihood of investigation and treatment of patients with coronary heart disease. DESIGN, PATIENTS, AND INTERVENTIONS: Routine discharge data were used to identify patients admitted with acute myocardial infarction (AMI) between 1991 and 1993 inclusive. Record linkage provided the proportion undergoing angiography, percutaneous transluminal coronary angioplasty (PTCA), and coronary artery bypass grafting (CABG) over the following two years. Multiple logistic regression analysis was used to determine whether age, sex, deprivation, and area of residence were independently associated with progression to investigation and revascularisation. SETTING: Mainland Scotland 1991 to 1995 inclusive. MAIN OUTCOME MEASURES: Two year incidence of angiography, PTCA, and CABG. Results-36 838 patients were admitted with AMI. 4831 (13%) underwent angiography, 587 (2%) PTCA, and 1825 (5%) CABG. Women were significantly less likely to undergo angiography (p < 0.001) and CABG (p < 0.001) but more likely to undergo PTCA (p < 0.05). Older patients were less likely to undergo all three procedures (p < 0.001). Socioeconomic deprivation was associated with a reduced likelihood of both angiography and CABG (p < 0.001). There were significant geographic variations in all three modalities (p < 0.001). CONCLUSION: Variations in investigation and management were demonstrated by age, sex, geography, and socioeconomic deprivation. These are unlikely to be accounted for by differences in need; differences in clinical practice are, therefore, likely.  (+info)

Chronic radiodermatitis following cardiac catheterisation: a report of two cases and a brief review of the literature. (2/8209)

Cardiac angiography produces one of the highest radiation exposures of any commonly used diagnostic x ray procedure. Recently, serious radiation induced skin injuries have been reported after repeated therapeutic interventional procedures using prolonged fluoroscopic imaging. Two male patients, aged 62 and 71 years, in whom chronic radiodermatitis developed one to two years after two consecutive cardiac catheterisation procedures are reported. Both patients had undergone lengthy procedures using prolonged fluoroscopic guidance in a limited number of projections. The resulting skin lesions were preceded, in one case, by an acute erythema and took the form of a delayed pigmented telangiectatic, indurated, or ulcerated plaque in the upper back or below the axilla whose site corresponded to the location of the x ray tube during cardiac catheterisation. Cutaneous side effects of radiation exposure result from direct damage to the irradiated tissue and have known thresholds. The diagnosis of radiation induced skin injury relies essentially on clinical and histopathological findings, location of skin lesions, and careful medical history. Interventional cardiologists should be aware of this complication, because chronic radiodermatitis may result in painful and resistant ulceration and eventually in squamous cell carcinoma.  (+info)

Recurring myocardial infarction in a 35 year old woman. (3/8209)

A 35 year old woman presented with acute myocardial infarction without any of the usual risk factors: she had never smoked; she had normal blood pressure; she did not have diabetes; plasma concentrations of total cholesterol and high and low density lipoprotein cholesterol, fibrinogen, homocysteine, and Lp(a) lipoprotein were normal. She was not taking oral contraceptives or any other medication. Coronary angiography showed occlusion of the left anterior descending coronary artery but no evidence of arteriosclerosis. Medical history disclosed a previous leg vein thrombosis with pulmonary embolism. Coagulation analysis revealed protein C deficiency. The recognition of protein C deficiency as a risk factor for myocardial infarction is important as anticoagulation prevents further thrombotic events, whereas inhibitors of platelet aggregation are ineffective.  (+info)

One-year survival among patients with acute myocardial infarction complicated by cardiogenic shock, and its relation to early revascularization: results from the GUSTO-I trial. (4/8209)

BACKGROUND: Although 30-day survival is increased in patients with acute myocardial infarction complicated by cardiogenic shock who undergo coronary revascularization, the longer-term outcome in such patients and the duration of benefit from revascularization are unknown. METHODS AND RESULTS: We analyzed 30-day survivors of acute myocardial infarction in the Global Utilization of Streptokinase and Tissue-Plasminogen Activator for Occluded Coronary Arteries (GUSTO-I) trial and identified 36 333 who had not had cardiogenic shock (systolic blood pressure <90 mm Hg for >/=1 hour, group 1) and 1321 patients who had shock (group 2). Group 2 patients were older and sicker. At 1 year, 97.4% of group 1 patients were alive versus 88.0% of group 2 (P=0.0001). Among group 2 patients, 578 (44%) had undergone revascularization within 30 days (group 2A) and 728 (56%) had not (group 2B). Revascularization was not required by protocol but was selected by the attending physicians. At 1 year, 91.7% of group 2A patients were alive versus 85.3% of group 2B (P=0.0003). With the use of multivariable logistic regression analysis to adjust for differences in baseline characteristics of shock patients alive at 30 days, revascularization within 30 days was independently associated with reduced 1-year mortality (odds ratio 0.6, [95% confidence interval 0.4, 0.9], P=0.007). CONCLUSIONS: Most patients (88%) with acute myocardial infarction complicated by cardiogenic shock who are alive at 30 days survived at least 1 year. Shock patients who underwent revascularization within 30 days had improved survival at 1 year compared with shock patients who did not receive revascularization, even after adjustment for differences in baseline characteristics between the 2 groups.  (+info)

Usefulness of fractional flow reserve to predict clinical outcome after balloon angioplasty. (5/8209)

BACKGROUND: After regular coronary balloon angioplasty, it would be helpful to identify those patients who have a low cardiac event rate. Coronary angiography alone is not sensitive enough for that purpose, but it has been suggested that the combination of optimal angiographic and optimal functional results indicates a low restenosis chance. Pressure-derived myocardial fractional flow reserve (FFR) is an index of the functional severity of the residual epicardial lesion and could be useful for that purpose. METHODS AND RESULTS: In 60 consecutive patients with single-vessel disease, balloon angioplasty was performed by use of a pressure instead of a regular guide wire. Both quantitative coronary angiography (QCA) and measurement of FFR were performed 15 minutes after the procedure. A successful angioplasty result, defined as a residual diameter stenosis (DS) <50%, was achieved in 58 patients. In these patients, DS and FFR, measured 15 minutes after PTCA, were analyzed in relation to clinical outcome. In those 26 patients with both optimal angiographic (residual DS by QCA /=0.90) results, event-free survival rates at 6, 12, and 24 months were 92+/-5%, 92+/-5%, and 88+/-6%, respectively, versus 72+/-8%, 69+/-8%, and 59+/-9%, respectively, in the remaining 32 patients in whom the angiographic or functional result or both were suboptimal (P=0.047, P=0.028, and P=0.014, respectively). CONCLUSIONS: In patients with a residual DS /=0.90, clinical outcome up to 2 years is excellent. Therefore, there is a complementary value of coronary angiography and coronary pressure measurement in the evaluation of PTCA result.  (+info)

New-onset sustained ventricular tachycardia after cardiac surgery. (6/8209)

BACKGROUND: The de novo occurrence of sustained ventricular tachycardia (VT) after CABG has been described, but the incidence, mortality rate, long-term follow-up, and mechanism are not well defined. METHODS AND RESULTS: This prospective study enrolled consecutive patients undergoing CABG at a single institution. Patients were followed up for the development of sustained VT, and a detailed analysis of clinical, angiographic, and surgical variables associated with the occurrence of VT was performed. A total of 382 patients participated, and 12 patients (3.1%) experienced >/=1 episode of sustained VT 4.1+/-4.8 days after CABG. In 11 of 12 patients, no postoperative complication explained the VT; 1 patient had a perioperative myocardial infarction. The in-hospital mortality rate was 25%. Patients with VT were more likely to have prior myocardial infarction (92% versus 50%, P<0.01), severe congestive heart failure (56% versus 21%, P<0.01), and ejection fraction <0.40 (70% versus 29%, P<0.01). When all 3 factors were present, the risk of VT was 30%, a 14-fold increase. Patients with VT had more noncollateralized totally occluded vessels on angiogram (1.4+/-0.97 versus 0.54+/-0.7, P<0.01), a bypass graft across a noncollateralized occluded vessel (1.50+/-1.0 versus 0.42+/-0.62, P<0.01), and a bypass graft across a noncollateralized occluded vessel to an infarct zone (1.50+/-1.0 versus 0.17+/-0.38, P<0.01). By multivariate analysis, the number of bypass grafts across a noncollateralized occluded vessel to an infarct zone was the only independent factor predicting VT. CONCLUSIONS: The first presentation of sustained monomorphic VT in the recovery period after CABG is uncommon, but the incidence is high in specific clinical subsets. Placement of a bypass graft across a noncollateralized total occlusion in a vessel supplying an infarct zone was strongly and independently associated with the development of VT.  (+info)

Comparison of quantitative coronary angiography, intravascular ultrasound, and coronary pressure measurement to assess optimum stent deployment. (7/8209)

BACKGROUND: Although intravascular ultrasound (IVUS) is the present standard for the evaluation of optimum stent deployment, this technique is expensive and not routinely feasible in most catheterization laboratories. Coronary pressure-derived myocardial fractional flow reserve (FFRmyo) is an easy, cheap, and rapidly obtainable index that is specific for the conductance of the epicardial coronary artery. In this study, we investigated the usefulness of coronary pressure measurement to predict optimum and suboptimum stent deployment. METHODS AND RESULTS: In 30 patients, a Wiktor-i stent was implanted at different inflation pressures, starting at 6 atm and increasing step by step to 8, 10, 12, and 14 atm, if necessary. After every step, stent deployment was evaluated by quantitative coronary angiography (QCA), IVUS, and coronary pressure measurement. If any of the 3 techniques did not yield an optimum result, the next inflation was performed, and all 3 investigational modalities were repeated until optimum stent deployment was present by all of them or until the treating physician decided to accept the result. Optimum deployment according to QCA was finally achieved in 24 patients, according to IVUS in 17 patients, and also according to coronary pressure measurement in 17 patients. During the step-up, a total of 81 paired IVUS and coronary pressure measurements were performed, of which 91% yielded concordant results (ie, either an optimum or a suboptimum expansion of the stent by both techniques, P<0.00001). On the contrary, QCA showed a low concordance rate with IVUS and FFRmyo (48% and 46%, respectively). CONCLUSIONS: In this study, using a coil stent, both IVUS and coronary pressure measurement were of similar value with respect to the assessment of optimum stent deployment. Therefore, coronary pressure measurement can be used as a cheap and rapid alternative to IVUS for that purpose.  (+info)

A randomized placebo-controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty; final results of the fluvastatin angiographic restenosis (FLARE) trial. (8/8209)

BACKGROUND: The 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors competitively inhibit biosynthesis of mevalonate, a precursor of non-sterol compounds involved in cell proliferation. Experimental evidence suggests that fluvastatin may, independent of any lipid lowering action, exert a greater direct inhibitory effect on proliferating vascular myocytes than other statins. The FLARE (Fluvastatin Angioplasty Restenosis) Trial was conceived to evaluate the ability of fluvastatin 40 mg twice daily to reduce restenosis after successful coronary balloon angioplasty (PTCA). METHODS: Patients were randomized to either placebo or fluvastatin 40 mg twice daily beginning 2-4 weeks prior to planned PTCA and continuing after a successful PTCA (without the use of a stent), to follow-up angiography at 26+/-2 weeks. Clinical follow-up was completed at 40 weeks. The primary end-point was angiographic restenosis, measured by quantitative coronary angiography at a core laboratory, as the loss in minimal luminal diameter during follow-up. Clinical end-points were death, myocardial infarction, coronary artery bypass graft surgery or re-intervention, up to 40 weeks after PTCA. RESULTS: Of 1054 patients randomized, 526 were allocated to fluvastatin and 528 to placebo. Among these, 409 in the fluvastatin group and 427 in the placebo group were included in the intention-to-treat analysis, having undergone a successful PTCA after a minimum of 2 weeks of pre-treatment. At the time of PTCA, fluvastatin had reduced LDL cholesterol by 37% and this was maintained at 33% at 26 weeks. There was no difference in the primary end-point between the treatment groups (fluvastatin 0.23+/-0.49 mm vs placebo 0.23+/-0.52 mm, P=0.95) or in the angiographic restenosis rate (fluvastatin 28%, placebo 31%, chi-square P=0.42), or in the incidence of the composite clinical end-point at 40 weeks (22.4% vs 23.3%; logrank P=0.74). However, a significantly lower incidence of total death and myocardial infarction was observed in six patients (1.4%) in the fluvastatin group and 17 (4.0%) in the placebo group (log rank P=0.025). CONCLUSION: Treatment with fluvastatin 80 mg daily did not affect the process of restenosis and is therefore not indicated for this purpose. However, the observed reduction in mortality and myocardial infarction 40 weeks after PTCA in the fluvastatin treated group has not been previously reported with statin therapy. Accordingly, a priori investigation of this finding is indicated and a new clinical trial with this intention is already underway.  (+info)

TY - JOUR. T1 - Discrepancy between computed tomography coronary angiography and selective coronary angiography in the pre-stenting assessment of coronary lesion length. AU - Soon, K. H.. AU - Farouque, H. M.O.. AU - Chaitowitz, I.. AU - Cox, N.. AU - Selvanayagam, J. B.. AU - Zakhem, B.. AU - Bell, K. W.. AU - Lim, Y. L.. PY - 2007/10/1. Y1 - 2007/10/1. N2 - We aimed to compare the lesion length measured on computed tomography coronary angiography (CT-CA) with the selective coronary angiography (SCA) lesion length measured on quantitative coronary angiography (QCA). Compared with SCA, CT-CA has the advantage of showing the lumen and the atherosclerotic plaque in the arterial wall. This prospective observational study involved 44 coronary lesions. Computed tomography coronary angiography was carried out with an electrocardiogram-gated 16-slice CT before percutaneous coronary intervention. A cardiologist and a radiologist measured CT lesion lengths in consensus, whereas an interventional ...
TY - JOUR. T1 - Positive predictive value of computed tomography coronary angiography in clinical practice. AU - Groothuis, J.G.J.. AU - Beek, A.M.. AU - Meijerink, M.R.. AU - Brinckman, S.L.. AU - Heijmans, M.W.. AU - van Kuijk, C.. AU - van Rossum, A.C.. PY - 2012. Y1 - 2012. N2 - Background: Several studies have investigated the diagnostic performance of computed tomography coronary angiography (CTCA) for the detection of significant coronary artery disease (CAD). These studies were performed in patients that were already referred for invasive coronary angiography (ICA) and prevalence of significant CAD was high. Although the negative predictive value of CTCA was consistently high, a wide range of positive predictive values (PPVs) was reported. Thus, the PPV of CTCA in patients that undergo CTCA as part of a clinical diagnostic evaluation remains unclear. This study investigated the PPV of CTCA for the detection of significant CAD in clinical practice. Methods: A total of 181 patients with ...
BACKGROUND: Quantitative flow ratio (QFR) is a novel diagnostic modality for functional testing of coronary artery stenosis without the use of pressure wires and induction of hyperemia. QFR is based on computation of standard invasive coronary angiographic imaging. The purpose of WIFI II (Wire-Free Functional Imaging II) was to evaluate the feasibility and diagnostic performance of QFR in unselected consecutive patients.. METHODS AND RESULTS: WIFI II was a predefined substudy to the Dan-NICAD study (Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease), referring 362 consecutive patients with suspected coronary artery disease on coronary computed tomographic angiography for diagnostic invasive coronary angiography. Fractional flow reserve (FFR) was measured in all segments with 30% to 90% diameter stenosis. Blinded observers calculated QFR (Medis Medical Imaging bv, The Netherlands) for comparison with FFR. FFR was measured in 292 lesions from 191 patients. Ten (5%) and 9 ...
Computed tomography coronary angiography (CTCA) has evolved as a non-invasive imaging technology that can be used as an alternative first-line diagnostic test in symptomatic patients with low to intermediate likelihood of coronary artery disease (CAD).1 Nevertheless, it has not (yet) fulfilled initial expectations that it would be able to replace conventional invasive coronary angiography because CTCA tends to overestimate the severity of the coronary stenosis, resulting in a number of patients with false-positive outcomes that is too high. This is mainly caused by the blooming effect of calcified lesions in combination with the still too limited spatial resolution of CTCA as compared with invasive coronary angiography. CTCA provides, additional to luminography, comprehensive assessment of the anatomical manifestations of coronary atherosclerosis, including the distribution (proximal, mid and distal) and extent (one-, two-, three-vessel disease, left main disease) of CAD, the presence of ...
Coronary angiography is a key diagnostic tool in the management of patients with coronary artery disease. Coronary angiography is used to identify narrowing in coronary arteries and is used for decision support to ascertain the need for revascularization to minimize the risk of myocardial infarction. Various research studies have evaluated trends in the use and results of coronary angiography as key contributory factors to the variations seen in rates for coronary revascularization across the US. For example, a large study by Chan, et al. highlighted that inappropriate revascularization rates ranged from 0% to 55% in different facilities[i]. The use of diagnostic angiography has been advocated in different guidelines to ensure that the revascularization is warranted, however, this approach does not address inappropriate selection of patients for a diagnostic angiography.. According to the American Heart Association (AHA), coronary angiography is not recommended in patients who are at low risk ...
The Combined Coronary angiography and myocardial perfusion imaging using 320 detectors computed tomography (CORE-320) was designed as a prospective, multi-center, international, blinded study designed to evaluate the diagnostic accuracy of multi-detector computed tomography using 320 detectors for identifying coronary artery luminal stenosis and corresponding myocardium perfusion defects in patients with suspected coronary artery disease. The primary analysis will be a comparison of the diagnostic capability of the combination of quantitative 320-MDCT angiography and quantitative perfusion imaging to the combination of conventional coronary angiography and SPECT myocardial perfusion imaging at the patient level. A positive patient will be defined as having at least one vessel with a ≥ 50% diameter stenosis defined by quantitative coronary angiography and a corresponding positive SPECT territorial myocardial perfusion defect ...
Coronary angiography remains the gold standard for imaging coronary anatomy and defining the extent and precise location of coronary artery disease. Optimal coronary angiography is dependent on a thorough knowledge of coronary anatomy and a systematic imaging sequence protocol that enables visualization of all coronary segments, particularly areas of vessel overlap, bifurcations, or tortuous anatomy. A basic map of the coronary anatomy is delineated in Figure 69-1, and the optimal views for imaging each coronary segment are summarized in Table 69-1 (Figs. 69-2, 69-3, 69-4, 69-5). Although standard views are generally consistent from one patient to the next, the precise angulations tend to vary based on the variations in anatomic orientations. A number of coronary segment numbering systems have been established; the most commonly used is the Coronary Artery Surgery Study (CASS) numbering system derived from the Bypass Angioplasty Revascularization Investigation (BARI) study,1 which assigns a ...
2020 Singapore Medical Association. All rights reserved. Computed tomography coronary angiography (CTCA) is a robust and reliable non-invasive alternative imaging modality to invasive coronary angiography, which is the reference standard in evaluating the degree of coronary artery stenosis. CTCA has high negative predictive value and can confidently exclude significant coronary artery disease (CAD) in low to intermediate risk patients. Over the years, substantial effort has been made to reduce the radiation dose and increase the cost efficiency of CTCA. In this review, we present the evolution of computed tomography scanners in the context of coronary artery imaging as well as its clinical applications and limitations. We also highlight the future directions of CTCA as a one-stop non-invasive imaging modality for anatomic and functional assessment of CAD ...
INTRODUCTION. Over the past few years, multidetector computed tomography (MDCT) has been demonstrated as a feasible alternative to invasive coronary angiography (ICA), allowing noninvasive evaluation of the coronary arteries.1-4 However, contradictory results have been reported regarding the effect of coronary artery calcium score (CS) on the diagnostic accuracy of MDCT.5,6 With the first generations of MDCT scanners, severe coronary calcifications were recognized as an important factor hampering precise evaluation of coronary artery stenosis, thereby limiting diagnostic accuracy. Calcified plaques produce artifacts (blooming) which may affect the evaluation of luminal obstruction.7 At the same time, more extensive coronary calcification increases the likelihood that the patient has obstructive coronary artery disease,8,9 and ICA is usually required for definitive diagnosis and treatment. Advances in temporal and spatial resolution, especially the introduction of 64-detector rows, and growing ...
TY - JOUR. T1 - Recent progress in quantitative coronary angiography. AU - Ozaki, Y.. AU - Keane, D.. AU - Serruys, P. W.. PY - 1995/1/1. Y1 - 1995/1/1. N2 - The recent progress of quantitative coronary angiography (QCA) has paralleled our advances in interventional cardiology and has contributed significantly to our current understanding of coronary artery disease. QCA offers a scientific medium for the study of acute procedural results and serial changes over long term follow up. Changes in the absolute minimal luminal diameter (MLD) have been utilized for the study of acute luminal gain and subsequent restenosis following coronary interventional procedures and changes in both the minimal and the mean luminal diameter (MEAN) have been utilized for the study of progression/regression of coronary artery disease. While there has been a growth in the deployment of videotape as a recording medium ml account of the recent development of digital acquisition systems, the suitability of video ...
Coronary angiography (an-jee-OG-ra-fee) is a test that uses dye and special x rays to show the inside of your coronary arteries. The coronary arteries supply blood and oxygen to your heart. A material called plaque can build up on the inside walls of the coronary arteries and cause them to narrow. When this happens, its called coronary artery disease (CAD). This can prevent enough blood from flowing to your heart and can lead to angina (an-JI-nuh or AN-juh-nuh) (chest discomfort or pain) and heart attack. Coronary angiography shows if you have CAD. Most of the time, the coronary arteries cant be seen on an x ray. During coronary angiography, a special dye is injected into the bloodstream to make the coronary arteries show up on an x ray. To deliver the dye to your coronary arteries, a procedure called cardiac catheterization (KATH-e-ter-i-ZA-shun) is used. A long, thin, flexible tube called a catheter is put into a blood vessel in your arm, groin (upper thigh), or neck. The tube is then ...
Dual imaging stress echocardiography, combining the evaluation of wall motion and coronary flow reserve (CFR) on the left anterior descending artery (LAD), and computed tomography coronary angiography (CTCA) are established techniques for assessing prognosis in chest pain patients. In this study we compared the prognostic value of the two methods in a cohort of patients with chest pain having suspected coronary artery disease (CAD). A total of 131 patients (76 men; age 68 ± 9 years) with chest pain of unknown origin underwent dipyridamole (up to 0.84 mg/kg over 6 min) stress echo with CFR assessment of LAD by Doppler and CTCA. A CFR ≤ 1.9 was considered abnormal, while | 50% lumen diameter reduction was the criterion for significant CAD at CTCA. Of 131 patients, 34 (26%) had ischemia at stress echo (new wall motion abnormalities), and 56 (43%) had reduced CFR on LAD. Significant coronary stenosis at CTCA was found in 69 (53%) patients. Forty-six patients (84%) with abnormal CFR on LAD showed
A look at the following clinical trial: Prevalence Of Internal Pudendal Artery Disease In Patients With Erectile Dysfunction Undergoing Diagnostic Coronary Angiography.
A 34-year-old Coloured man had typical angina pectoris which was unresponsive to medical therapy. There was no history of factors predisposing to atherosclerosis apart from moderate cigarette smoking. A resting ECG suggested a previous nontransmural anterolateral myocardial infarction, and a submaximal effort test was strongly positive for myocardial ischaemia. Serological investigation for syphilis was positive, and initially the possibility that coronary ostial stenosis was the cause of his symptoms was strongly considered. Cardiac catheterization and selective coronary angiography showed evidence of an anterolateral myocardial infarction and that there was no coronary ostial stenosis, but total occlusion of the left anterior descending coronary artery (LAD) proximally with retrograde filling from the right coronary artery was revealed. The left circumflex coronary artery also showed some insignificant internal luminal irregularities. The patient was subjected to coronary artery bypass graft ...
TY - JOUR. T1 - Rapid disappearance of an endothelial ulceration in the left main coronary artery. AU - Bokhari, Ismail A H. AU - Bokhari, Ravia. AU - Alpert, Joseph S. PY - 2007/3. Y1 - 2007/3. N2 - A case is presented of a 65-year-old male who presented with an acute anterior wall myocardial infarction. An initial coronary angiogram demonstrated an ulcerated atherosclerotic plaque in the left main coronary artery. After 48 h of aggressive medical therapy including a 2b3a glycoprotein blocking agent, repeat angiography demonstrated resolution of the ulcerated plaque. The process of atherosclerotic plaque rupture is of dynamic nature.. AB - A case is presented of a 65-year-old male who presented with an acute anterior wall myocardial infarction. An initial coronary angiogram demonstrated an ulcerated atherosclerotic plaque in the left main coronary artery. After 48 h of aggressive medical therapy including a 2b3a glycoprotein blocking agent, repeat angiography demonstrated resolution of the ...
Learn more about Coronary Artery Angiography (Cardiac Catheterization) at Memorial Hospital function replaceEmbed(anmationName, embedContainerName) { var...
TY - JOUR. T1 - Contemporary trends in coronary intervention. T2 - A report from the registry of the society for cardiac angiography and interventions. AU - Laskey, Warren K.. AU - Kimmel, Steven. AU - Krone, Ronald J.. PY - 2000/1/17. Y1 - 2000/1/17. N2 - This report of the Registry for the Society for Cardiac Angiography and Interventions provides data on the trends in coronary interventional procedures from the time period June 1966 through December 1998. A total of 19,510 consecutive coronary interventional procedures were recorded. Over this time period, significant trends in coronary stent implantation were recorded along with a decreasing reliance on balloon angioplasty as sole therapy. Patients with acute myocardial infarction comprised an increased fraction of all procedures. Almost half of all interventions were performed in patients with multivessel disease. Finally, decreasing rates of in- hospital death and emergent bypass surgery compared to prior reports from the registry ...
TY - JOUR. T1 - Anthropometric and bioclinical parameters in patients of coronary artery disease. AU - Venugopal, D.. AU - Vishesh, K.. AU - Shyamala, K. V.. PY - 2012/7/1. Y1 - 2012/7/1. N2 - The economic burden of CAD on any country is tremendous. It is expected that the rate of CAD will accelerate in the next decade. The obstructive impairment and number of vessels affected can interfere with the therapeutic strategy. Selective coronary angiography is the clinical diagnostic test for evaluating the coronary anatomy. Therefore, we can presume that if anthropometric values and biochemical parameters are predictive of the degree of anatomical impairment on coronary angiography, it will potentially be able to influence the decision of a strategy on invasive investigation in patients with ACS. Our project is hence an Endeavour to study the anthropometric and bioclinical profile of the patients with coronary artery disease and assessing them in relation to their angiographic severity. Methods: 100 ...
To study the role of 320-detector coronary computed tomography angiography (CTA) in assessing native coronary arteries in patients treated with coronary stents. 123 patients with coronary stenting received both CTA and conventional coronary angiography (CCA) within 1 day. The clinical parameters, coronary calcium scoring, CTA and CCA were analyzed to determine the prevalence of significant stenosis of native coronary arteries (SSNCA), the predictive value of CTA and the factors correlating with SSNCA and newly developed SSNCA after stenting (NDSSNCAS), with CCA as the standard of reference, using both vessel-based analysis (VBA) and patient-based analysis (PBA). Both the source and the reconstructed images were analyzed by CTA. All native coronary arteries were interpretable independent of cardiac motion. CTA showed a sensitivity/specificity of 93.5 %/97.3 % and 92.5 %/92.5 % in diagnosing SSNCA in VBA and PBA, respectively. The significant factors related to SSNCA were higher calcium scores (P ...
TY - JOUR. T1 - Automated Interpretation and Reporting of Coronary CT Coronary Angiography. AU - Rajiah, Prabhakar. AU - Schoenhagen, Paul. PY - 2013/6. Y1 - 2013/6. N2 - Coronary CT angiography (CTA) has become a well-accepted imaging modality in the evaluation of coronary artery disease (CAD) due to its high negative predictive value. The ability to exclude CAD in patients presenting with chest pain in a low to intermediate risk population makes it very useful in emergency departments for optimizing resource utilization and reducing expenditure. The limited availability of trained cardiac imagers is a potential obstacle in implementing this strategy. Towards the goal of prompt and accurate interpretation of coronary CTA, there has been a recent interest in the development of automated coronary CTA interpretation and reporting. This article aims to review the current applications and scientific evidence on the utility of automated techniques for interpretation and reporting of coronary ...
Acute coronary obstruction occurred in two patients during coronary angiography. In one case the obstruction was in the left main coronary artery; in the other it was close to the origin of the left anterior descending artery. In both cases acute cardiac ischaemia ensued, with electromechanical dissociation and collapse, which was not reversible by resuscitation. Rapid disobliteration of the occluded coronary artery was done with a guide-wire pushed through the obstruction via the coronary catheter. The recanalisation was completed by an intracoronary perfusion of streptokinase in one case. In both cases recovery was rapid and spectacular. The occurrence of acute ischaemia during coronary angiography should suggest accidental coronary occlusion. If a thromboembolic origin is suspected, transluminal disobliteration should be attempted. It is simple and can reverse a dangerous condition ...
When coronary artery disease is extensive and of relatively uniform severity, regional myocardial hypoperfusion may be balanced during stress, precluding development of spatially relative perfusion defects. Assessment of the washout of thallium-201 from myocardial regions may provide diagnostic assistance in these cases because washout analysis is spatially nonrelative and hypoperfused myocardial regions manifest a slow thallium-201 washout rate. In 1,265 consecutive patients having quantitatively analyzed stress-redistribution scintigraphy, 46 had a diffuse slow washout pattern with no or a maximum of one regional perfusion defect. Thirty-two underwent clinically indicated coronary angiography, and 23 (72%) of these were found to have three vessel or left main disease. Of 30 similar patients without a diffuse slow washout pattern and with no or a maximum of one perfusion defect, only 5 (17%) had extensive coronary disease. An independent relation between diffuse slow washout and extensive ...
Have we then found the holy grail of non-invasive coronary imaging?. The ability to visualise coronary arteries directly, assess cardiac function, and detect subclinical disease from a 20 second scan make MDCT more attractive than conventional stress testing. However, the significant radiation exposure makes it unattractive to screen the low risk population. Similarly, there is no justification for imaging high risk patients who clearly require coronary angiography and percutaneous intervention, without additional radiation exposure. It is unlikely that the financially constrained UK health system will adopt routine MDCT in the accident and emergency department to triage chest pain patients for rule out of pulmonary embolism, aortic dissection, and coronary disease.. The present niche of MDCT should be as an adjunct to coronary catheterisation in the assessment of patients and a useful gatekeeper ensuring appropriate triage of patients for catheterisation. This is especially true in the ...
Subjects in this study have recently had or are scheduled for a coronary angiography as part of their normal, routine medical care. This procedure uses x-ray imaging to see the inside of the hearts blood vessels.. This research study will evaluate the possible relationship between erectile dysfunction and vascular disease (diseases of the veins). In order to look at this possible relationship, subjects will complete a questionnaire which will ask questions regarding their sexual activity. Additionally, we will gather information from their medical records and take extra images during the coronary angiography procedure. ...
AIMS: To evaluate the diagnostic power of integrating the results of computed tomography angiography (CTA) and CT myocardial perfusion (CTP) to identify coronary artery disease (CAD) defined as a flow limiting coronary artery stenosis causing a perfusion defect by single photon emission computed tomography (SPECT). METHODS AND RESULTS: We conducted a multicentre study to evaluate the accuracy of integrated CTA-CTP for the identification of patients with flow-limiting CAD defined by ≥50% stenosis by invasive coronary angiography (ICA) with a corresponding perfusion deficit on stress single photon emission computed tomography (SPECT/MPI). Sixteen centres enroled 381 patients who underwent combined CTA-CTP and SPECT/MPI prior to conventional coronary angiography. All four image modalities were analysed in blinded independent core laboratories. The prevalence of obstructive CAD defined by combined ICA-SPECT/MPI and ICA alone was 38 and 59%, respectively. The patient-based diagnostic accuracy ...
Coronary calcium predicts the angiographic extent of CAD in symptomatic patients and provides independent and incremental information to the more conventional clinical parameters derived from SPECT or risk assessment.
Results of the ReACT Trial Presented at TCT 2016 and Published Simultaneously in JACC: Cardiovascular Interventions. WASHINGTON - November 1, 2016 - A randomized evaluation of routine follow-up coronary angiography after percutaneous coronary intervention (PCI) found that there was no long-term clinical benefit compared to clinical follow-up alone among unselected patients following PCI.. Findings from the ReACT trial were reported today at the 28th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the worlds premier educational meeting specializing in interventional cardiovascular medicine. The study was also simultaneously published in JACC: Cardiovascular Interventions.. In this prospective, multicenter, open label, randomized study, patients who underwent successful PCI without planned staged PCI were randomly assigned to the routine angiographic follow-up (AF) group, in which they received coronary ...
TY - JOUR. T1 - Impact of contrast agent type (ionic versus nonionic) used for coronary angiography on angiographic, electrocardiographic, and clinical outcomes following thrombolytic administration in acute myocardial infarction. AU - Michael Gibson, C.. AU - Kirtane, Ajay J.. AU - Murphy, Sabina A.. AU - Marble, Susan J.. AU - de Lemos, James A. AU - Antman, Elliot M.. AU - Braunwald, Eugene. PY - 2001/5/16. Y1 - 2001/5/16. N2 - The goal of this study was to examine the relationship between contrast agent type (ionic vs. nonionic) and angiographic, electrocardiographic, and clinical outcomes after thrombolytic administration. Ionic or nonionic contrast agents were selected in a nonrandomized fashion for 90-min angiography and percutaneous coronary intervention (PCI) following thrombolytic administration in the TIMI 14 trial [tissue plasminogen activator (tPA) or reteplase (rPA) vs. low-dose lytic + abciximab]. There was no relationship between contrast agent type and overall patency, rate of ...
High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis Jae-Beom Lee,1 Yun-Seok Choi,2 Woo-Baek Chung,2 Ami Kwon,2 Chul-Soo Park,2 Man-Young Lee2 1Anyang Sam Hospital, 2Division of Cardiology, Department of Internal Medicine, Youido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Purpose: High coronary calcium score (CCS) and post-procedural cardiac enzyme may be related with poor outcomes in patients with coronary stent implantation. Methods: A total of 1,072 patients (63.2% male, mean age: 61.7±10.3 years) who underwent coronary multi-detect computed tomography at index procedure and follow-up coronary angiography (CAG) after drug-eluting stent (DES) were divided into two groups: those with and without target lesion revascularization (TLR; >50% reduction in luminal stent diameter or angina symptoms on follow-up CAG). The CCSs for predicting stent revascularization were elucidated. Results:
Anomalous coronary arteries: Location, degree of atherosclerosis and effect on survival-a report from the Coronary Artery Surgery Study. J Am Coll Cardiol, 1989, 12, 531- 7. 27. , et al. Coronary anatomy in congenitally corrected transposition of the great arteries. Int J Cardiol, 2002, 86, 207-16. 28. B. Congenital heart defects and coronary anatomy. Tex Heart Inst J, 2002, 29, 279-89. 29. , et al. Influence of coronary anatomy on the anatomic repair of transposition of great arteries. Rev Esp Cardiol, 1996, 49, 451-6. Clinical importance of intramural blood vessels in the sino-atrial segment of the conducting system of the heart. Surg Radiol Anat, 1997, 19, 359-63. 17. , et al. A clinical angiographic study of the arterial blood supply to the sinus node. Chest, 1988, 94, 1054-7. 18. Gorlin, R. Coronary anatomy. Major Probl Intern Med, 1976, 11, 40-58. 19. , P. D. Leachman. Variations in coronary artery anatomy: Normal versus abnormal. Cardiovasc Dis, 1980, 7, 357- 70. 20. Angelini, P. Normal ...
Early identification of vulnerable plaques by remodeling index prior to rupture and development of acute event is of considerable importance especially by a reliable non-invasive method as CT coronary angiography (CTA), so we aim to evaluate coronary artery remodeling index in patients with low- to intermediate-risk stable angina by CTA. This single-center, cross-sectional, observational study included 150 patients with stable angina with normal resting ECG, negative markers, normal systolic function by 2D echocardiography (EF | 50%), and without regional wall motion abnormality at rest who were referred to MSCT evaluation of the coronary artery tree; the mean age was 56.8 ± 6.4 years, 83.3% had one-vessel disease, and 16.7% had two-vessel diseases. The mean remodeling index (RI) was 1.04 ± 0.28, 38% had significant positive remodeling, LAD was the most affected vessel (55.3), and proximal lesions were predominant in 48.5%; there was a statistically significant positive correlation between RI and
Routinely measuring fractional flow reserve (FFR) with pressure wire assessment during coronary angiography for diagnosis of chest pain leads to significan
PURPOSE: To evaluate the performance of a computer aided algorithm for automated stenosis detection at coronary CT angiography (cCTA) using quantitative coronary angiography (QCA) as the reference standard.. METHODS: 59 patients (38 men, mean age 58±12y) underwent cCTA and QCA. In 29 patients cCTA was performed using dual-source CT (Definition™, Siemens, Forchheim, Germany) and in 30 patients using 64-slice CT (Sensation 64™, Siemens). All cCTA data sets were analyzed using a software algorithm (COR Analyzer™, Rcadia, Haifa, Israel) aimed at automated detection of coronary artery stenosis. The performance of the automated algorithm for detection of significant (≥50%) stenosis was compared with QCA based on a 10-segment coronary model. Performance of the automated algorithm was determined on a per-vessel and per-patient basis.. RESULTS: All cCTA data sets were successfully processed by the automated algorithm. QCA revealed a total of 40 stenoses ≥50% of which the software application ...
Measuring fractional flow reserve (FFR) during coronary angiography for diagnosis of chest pain can provide significant changes in the management of almost quarter of the patients.
TY - GEN. T1 - Feature-based non-rigid volume registration of serial coronary CT angiography. AU - Woo, Jonghye. AU - Hong, Byung Woo. AU - Dey, Damini. AU - Cheng, Victor. AU - Ramesh, Amit. AU - Sundaramoorthi, Ganesh. AU - Kuo, C. C.Jay. AU - Berman, Daniel S.. AU - Germano, Guido. AU - Slomka, Piotr J.. PY - 2009/12/15. Y1 - 2009/12/15. N2 - Coronary CT angiography (CTA) with multi-slice helical scanners is becoming the integral part of major diagnostic pathways for coronary artery disease. In addition, coronary CTA has demonstrated substantial potential in quantitative coronary plaque characterization. If serial comparisons of plaque progression or regression are to be made, accurate 3D volume registration of these volumes would be particularly useful. In this work, we propose a coronary CTA volume registration of the paired coronary CTA scans using feature-based non-rigid volume registration. We achieve this with a combined registration strategy, which uses the global rigid registration as ...
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TY - JOUR. T1 - Long-term prognostic utility of computed tomography coronary angiography in older populations. AU - Gnanenthiran, Sonali R.. AU - Naoum, Christopher. AU - Leipsic, Jonathon A.. AU - Achenbach, Stephan. AU - Al-Mallah, Mouaz H.. AU - Andreini, Daniele. AU - Bax, Jeroen J.. AU - Berman, Daniel S.. AU - Budoff, Matthew J.. AU - Cademartiri, Filippo. AU - Callister, Tracy Q.. AU - Chang, Hyuk Jae. AU - Chinnaiyan, Kavitha. AU - Chow, Benjamin J.W.. AU - Cury, Ricardo C.. AU - Delago, Augustin. AU - Feuchtner, Gudrun. AU - Hadamitzky, Martin. AU - Hausleiter, Joerg. AU - Kaufman, Philipp A.. AU - Kim, Yong Jin. AU - Maffei, Erica. AU - Marques, Hugo. AU - De Araújo Goncalves, Pedro. AU - Pontone, Gianluca. AU - Raff, Gilbert L.. AU - Rubinshtein, Ronen. AU - Shaw, Leslee J.. AU - Villines, Todd C.. AU - Gransar, Heidi. AU - Lu, Yao. AU - Jones, Erica C.. AU - Penã, Jessica M.. AU - Lin, Fay Y.. AU - Kritharides, Leonard. AU - Min, James K.. PY - 2019/11/1. Y1 - 2019/11/1. N2 - Aims: ...
Evidence-based recommendations on QAngio XA 3D QFR and CAAS vFFR imaging software for assessing coronary stenosis during invasive coronary angiography
Pre-operative assessment of coronary artery disease with conventional coronary angiography has been recommended in the guidelines of the American College of Cardiology/American Heart Association for selected patients scheduled for cardiac valve surgery (15). Recently introduced multislice CT allows noninvasive coronary artery imaging and has been shown to reliably exclude significant coronary artery stenosis (8,9). The major advantage of multislice CT over conventional coronary angiography in patients with acute IE is its noninvasiveness and thus avoidance of the high embolization risk of valvular vegetations during catheter manipulation. Once spread into the systemic arterial circulation, those vegetations can cause severe complications such as cerebral or peripheral embolization (17).. In this study, multislice CT showed an excellent diagnostic performance in assessing morphologic abnormalities commonly seen in patients with IE. Accuracy of vegetation, abscess, and pseudoaneurysm detection ...
Introduction: Coronary CT angiography (CCTA) is an accurate and emerging diagnostic tool for evaluation of patients suspected of having coronary artery disease (CAD). Data on downstream testing, patient management and prognosis are important to further delineate the role of CCTA in clinical practice.. Hypothesis: We hypothesized that a normal CCTA in symptomatic patients does not lead to multiple diagnostic testing, influences patient management and indicates a favorable prognosis.. Methods: Prospective observational investigation of consecutive chest pain patients (without known CAD) having a normal 64-slice dual source CCTA study (no coronary plaques) from February 2007 to April 2009. Patient use of anitplatelet and lipid lowering therapy before and after the index CCTA, the use of additional downstream diagnostic testing (stress testing, myocardial perfusion imaging and invasive coronary angiography), and the occurrence of all-cause death or non-fatal myocardial infarction was recorded from ...
Objectives: To evaluate the diagnostic and prognostic benefits of CT coronary angiography (CTCA) using the 2016 National Institute for Health and Care Excellence (NICE) guidelines for the assessment of suspected stable angina. Methods: Post hoc analysis of the Scottish COmputed Tomography of the HEART (SCOT-HEART) trial of 4146 participants with suspected angina randomised to CTCA. Patients were dichotomised into NICE guideline-defined possible angina and non-anginal presentations. Primary (diagnostic) endpoint was diagnostic certainty of angina at 6 weeks and prognostic endpoint comprised fatal and non-fatal myocardial infarction (MI). Results: In 3770 eligible participants, CTCA increased diagnostic certainty more in those with possible angina (relative risk (RR) 2.22 (95% CI 1.91 to 2.60), p,0.001) than those with non-anginal symptoms (RR 1.30 (1.11 to 1.53), p=0.002; pinteraction ,0.001). In the possible angina cohort, CTCA did not change rates of invasive angiography (p=0.481) but markedly ...
About Coronary Angiography Coronary Angiography, or Angiogram, is a minimally invasive procedure which is done to show the amount of coronary artery disease in the blood vessels that supply the heart. Coronary arteries can become clogged from a build-up of cholesterol, cells or other substances (plaque). This can reduce the flow of blood to your heart, causing chest pain,
TY - JOUR. T1 - Likelihood of obstructive coronary disease in metabolic syndrome patients with abnormal stress echocardiography. AU - Al Badarin, Firas J.. AU - From, Aaron M.. AU - McCully, Robert B.. AU - Lopez-Jimenez, Francisco. PY - 2011/10/20. Y1 - 2011/10/20. N2 - Background: Metabolic syndrome (MetSx) encompasses several risk factors for macrovascular coronary artery disease. An association between MetSx and coronary syndrome X has also been reported, suggesting that patients with MetSx are more likely to have endothelial dysfunction in the setting of angiographically normal coronary arteries. It remains unknown whether MetSx patients with abnormal stress echocardiography (SE) are more likely to have obstructive coronary disease (CAD) compared to patients without MetSx. Methods: We identified symptomatic patients without known CAD and abnormal SE who underwent coronary angiography within 4 weeks after the SE. Patients were grouped according to their MetSx and impaired fasting glucose ...
TY - JOUR. T1 - Metabolic syndrome and angiographic coronary artery disease prevalence in association with the framingham risk score. AU - Konstantinou, Dimitris M.. AU - Chatzizisis, Yiannis S.. AU - Louridas, George E.. AU - Giannoglou, George D.. PY - 2010/6/1. Y1 - 2010/6/1. N2 - Background: The association of metabolic syndrome with coronary artery disease (CAD) has been studied extensively. However, little is known about the effect of Framingham risk score (FRS) and metabolic syndrome components on the association of metabolic syndrome with angiographically significant CAD. Our aim was to investigate whether that relationship is influenced by individuals 10-year CAD risk profile as assessed by FRS. Furthermore, we sought to elucidate whether metabolic syndrome is associated with angiographically significant CAD independently of its individual components. Methods: We studied a consecutive sample of 150 patients undergoing coronary angiography for the evaluation of chest pain. Metabolic ...
TY - JOUR. T1 - Internal pudendal artery stenoses and erectile dysfunction. T2 - Correlation with angiographic coronary artery disease. AU - Rogers, Jason H. AU - Karimi, Houshang. AU - Kao, John. AU - Link, Daniel P. AU - Javidan, Javid. AU - Yamasaki, Dwayne S.. AU - Dolan, Mark. AU - Laird, John R.. AU - Low, Reginald. PY - 2010/11/15. Y1 - 2010/11/15. N2 - Objectives: To describe the angiographic characteristics of pelvic arterial disease in patients with erectile dysfunction (ED) nonresponsive to phosphodiesterase-5 inhibitors (PDE5i) and suspected coronary artery disease (CAD). Background: ED and CAD share common risk factors which can result in endothelial dysfunction, atherosclerosis and flow-limiting stenoses in the coronary and internal pudendal arteries. Methods: Ten patients undergoing cardiac catheterization with ED and a history of unsatisfactory response to a PDE5i were studied. ED severity was quantified using the International Index of ED scoring system. We performed angiography ...
OBJECTIVES: This study sought to ascertain the relationship of 9p21 locus with: 1) angiographic coronary artery disease (CAD) burden; and 2) myocardial infarction (MI) in individuals with underlying CAD. BACKGROUND: Chromosome 9p21 variants have been robustly associated with coronary heart disease, but questions remain on the mechanism of risk, specifically whether the locus contributes to coronary atheroma burden or plaque instability. METHODS: We established a collaboration of 21 studies consisting of 33,673 subjects with information on both CAD (clinical or angiographic) and MI status along with 9p21 genotype. Tabular data are provided for each cohort on the presence and burden of angiographic CAD, MI cases with underlying CAD, and the diabetic status of all subjects. RESULTS: We first confirmed an association between 9p21 and CAD with angiographically defined cases and control subjects (pooled odds ratio [OR]: 1.31, 95% confidence interval [CI]: 1.20 to 1.43). Among subjects with angiographic CAD (n
BACKGROUND: Patients with obstructive left main coronary artery disease are usually treated with coronary-artery bypass grafting (CABG). Randomized trials have suggested that drug-eluting stents may be an acceptable alternative to CABG in selected patients with left main coronary disease. METHODS: We randomly assigned 1905 eligible patients with left main coronary artery disease of low or intermediate anatomical complexity to undergo either percutaneous coronary intervention (PCI) with fluoropolymer-based cobalt-chromium everolimus-eluting stents (PCI group, 948 patients) or CABG (CABG group, 957 patients). Anatomic complexity was assessed at the sites and defined by a Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score of 32 or lower (the SYNTAX score reflects a comprehensive angiographic assessment of the coronary vasculature, with 0 as the lowest score and higher scores [no upper limit] indicating more complex coronary anatomy). The primary end point was
We have developed a novel approach that allows rapid computation of FFR during diagnostic coronary angiography. In the study population of 73 patients with intermediate coronary lesions in 84 vessels, the QFR showed good agreement with the pressure wire-determined standard FFR measurements. The agreement was particularly favorable with QFR derived from contrast-flow (cQFR) and adenosine-flow models (aQFR), which both incorporated patient-specific flow by frame count analysis. Positive and negative likelihood ratios were of diagnostic value for use in the individual patient with cQFR and aQFR, although the positive likelihood ratio was of insufficient diagnostic value to be clinically useful with fQFR and a DS% of ≥50% (21).. In this study, the vessel-based diagnostic accuracy for determining the functional significance of an intermediate stenosis (i.e., FFR ≤ 0.80) was only 65%, if based on a single 3D QCA anatomic parameter of diameter stenosis of ≥50%. This is in line with a recent study ...
TY - JOUR. T1 - Noninvasive visualization of the left main coronary artery by cross sectional echocardiography. AU - Weyman, A. E.. AU - Feigenbaum, Harvey. AU - Dillon, J. C.. AU - Johnston, K. W.. AU - Eggleton, R. C.. PY - 1976. Y1 - 1976. N2 - Real time cross sectional echocardiographic studies of the left main coronary artery (LMCA) were performed in 15 normal patients, 15 patients with angiographically proven coronary artery disease but normal left main coronary segments, three patients with greater than 75% obstruction of the left main coronary artery, and one patient with a large aneurysm of the left main coronary artery. In normal subjects the LMCA evaginates from the inferolateral wall of the aorta. The artery appears as two dominant parallel linear echoes separated by a clear space representing the lumen of the vessel. The LMCA courses beneath the right ventricular outflow tract and can generally be followed to its expected point of bifurcation. Confirmation that this structure was in ...
BACKGROUND: In patients with non-ST-segment elevation acute coronary syndrome (NSTEACS), coronary pathology may range from structurally normal vessels to severe coronary artery disease.. OBJECTIVES: The purpose of this study was to test if coronary computed tomography angiography (CTA) may be used to exclude coronary artery stenosis ≥50% in patients with NSTEACS.. METHODS: The VERDICT (Very Early Versus Deferred Invasive Evaluation Using Computerized Tomography in Patients With Acute Coronary Syndromes) trial (NCT02061891) evaluated the outcome of patients with confirmed NSTEACS randomized 1:1 to very early (within 12 h) or standard (48 to 72 h) invasive coronary angiography (ICA). As an observational component of the trial, a clinically blinded coronary CTA was conducted prior to ICA in both groups. The primary endpoint was the ability of coronary CTA to rule out coronary artery stenosis (≥50% stenosis) in the entire population, expressed as the negative predictive value (NPV), using ICA as ...
BACKGROUND: In patients with non-ST-segment elevation acute coronary syndrome (NSTEACS), coronary pathology may range from structurally normal vessels to severe coronary artery disease.. OBJECTIVES: The purpose of this study was to test if coronary computed tomography angiography (CTA) may be used to exclude coronary artery stenosis ≥50% in patients with NSTEACS.. METHODS: The VERDICT (Very Early Versus Deferred Invasive Evaluation Using Computerized Tomography in Patients With Acute Coronary Syndromes) trial (NCT02061891) evaluated the outcome of patients with confirmed NSTEACS randomized 1:1 to very early (within 12 h) or standard (48 to 72 h) invasive coronary angiography (ICA). As an observational component of the trial, a clinically blinded coronary CTA was conducted prior to ICA in both groups. The primary endpoint was the ability of coronary CTA to rule out coronary artery stenosis (≥50% stenosis) in the entire population, expressed as the negative predictive value (NPV), using ICA as ...
Background: Coronary artery disease is sometimes associated with chronic conduction block. Our aim is to correlate between chronic conduction block and coronary artery disease. We performed ECG and coronary angiography of all patients who were admitted for permanent pacemaker implantation to find correlation between them. Methods: Coronary angiography was performed in all 160 patients of chronic conduction block during twenty four months of study period who were admitted for pacemaker implantation. We compared the coronary artery disease in different types of conduction block. Results: Among the study population 35(22%) patients are of single vessel coronary artery disease (CAD),13 (8%) patients had double vessel coronary artery disease, 6 (4%) patients had triple vessel coronary artery disease, 2 (1%) patients had left main disease and 104 (65%) patients had normal or insignificant coronary anatomy. Conclusion: Coronary artery disease is quite common in chronic conduction disorder. So there ...
Endogenous oxidative DNA damage is caused by multiple endogenous and exogenous factors. It is not completely known whether coronary angiography has an effect on DNA damage. The aim of this study was to investigate whether coronary angiography causes oxidative DNA damage. Fifty-four patients who underwent elective coronary angiography for diagnostic purpose were enrolled to the study. For each subject, the frequency of oxidative DNA damage was analyzed by using the comet assay, which is a sensitive biomarker of DNA damage, before and after diagnostic procedures. A highly significant increase of DNA damage mean score was observed in all patients after the coronary angiography procedure (p < 0.001). No significant associations were found between the change in oxidative DNA damage and dose of contrast media and radiation exposure time. A significant correlation was observed between the change of DNA damage and age, hyperlipidemia, hypertension, smoking, Gensini score index, and vitamin B,2 (r = ...
Background and Purpose: Acute myocardial infarction(AMI) occurs in 1-2% of patients treated with carotid artery stenting(CAS), and is considered as one of the most serious perioperative complication. We assessed coronary artery stenosis in patients treated with CAS using coronary CTA or coronary angiography.. Methods: Consecutive sixty-two patients (47 men, mean age 73.4 years) treated with CAS were examined by coronary CTA or angiography within 3 months before CAS between January 2010 and August 2012. In patients suspected coronary artery stenosis by coronary CTA, coronary angiography was performed. Significantly coronary artery stenosis was defined as that greater than 75%.. Results: CAS was performed in 62 patients, and coronary artery was evaluated in 57 patients. Patients with allergic reaction for contrast agents, renal failure, and poor general condition were excluded from this study. Thirty-eight patients had significant coronary artery stenosis. Twenty-nine of them had any history of ...
Definition of Left main coronary artery in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Left main coronary artery? Meaning of Left main coronary artery as a legal term. What does Left main coronary artery mean in law?
The role of vaspin in the pathogenesis of stable coronary artery disease (SCAD) have been repeatedly addressed in clinical studies. However, from the point of view of clinical practice, the results of earlier studies are still inconclusive. The data of 106 SCAD patients who received coronary angiography and 85 coronary artery disease-free controls were collected and analysed. The patients were divided into subgroups according to their pre-test probability (PTP) and according to the result of coronary angiography. Fasting vaspin concentrations were compared between subgroups of SCAD patients and between target group and controls. The effect of age and smoking on the result of coronary angiography was compared to the effect of vaspin using the binomial regression. We did not find significant difference in vaspin level between target group and controls. Unless the pre-test probability was taken into account, we did not find vaspin difference in the target group, when dividing patients on the basis of
Background: Although a shorter hemostasis duration would be expected when compared with the conventional radial approach as the diameter of the distal radial artery is smaller than that of the conventional radial artery, the optimal duration of hemostasis in diagnostic coronary angiography (CAG) via the distal radial approach, termed the snuffbox approach, has not been well investigated. Methods: Data from 171 patients were retrospectively collected (55 and 116 patients in the 4-French [Fr] and 5-Fr sheath groups, respectively). The patients had suspected myocardial ischemia and were undergoing diagnostic CAG via the snuffbox approach at a single center between January 2019 and August 2019. Results: The mean age of the study population was 67.6 ± 11.0 years, and 69% were male. The left snuffbox approach was performed in 146 (85.4%) patients. The mean snuffbox puncture time, defined as the time interval between local anesthesia and sheath cannulation, was 145.1 ± 120.8 s. The hemostasis ...
Background The dimensions of the coronary arteries have been shown to vary among ethnic groups. There are no data available regarding the normal size of coronary arteries in Iranians. This study aimed to investigate normal coronary artery dimensions in a Northwestern Iranian population and to compare it with pooled data of Indo-Asians and Caucasians in previous studies. Methods The study included 200 adults with suspected coronary disease who were referred for elective coronary angiography between June 2012 and March 2013 and were found to have normal epicardial flow in the coronary arteries. Quantitative coronary angiography was carried out on the longest atheroma-free part of the proximal segment of each coronary artery in all patients. Two Indo-Asian and Caucasian groups were selected and pooled for comparison with the available reports on individuals without coronary artery disease. Results The mean diameters of the left main coronary artery, proximal left anterior descending artery, ...
BACKGROUND: Adverse cardiac event rates are higher for percutaneous coronary intervention (PCI) of bifurcation lesions. Currently, provisional stenting or a simple stenting strategy is the standard treatment for bifurcated lesions, but its performance remains limited because of a risk of side-branch (SB) closure and a higher rate of target lesion revascularization (TLR). We report a new provisional side-branch stenting strategy to treat coronary bifurcation lesions using a balloon-stent kissing technique (BSKT).. METHODS: From January 2011 to December 2012, a total of 60 patients with 60 bifurcation lesions underwent PCI using BSKT. Baseline and postprocedural quantitative coronary angiography (QCA) analyses were performed. Procedural and immediate clinical outcomes were reviewed.. RESULTS: The majority of patients presented with acute coronary syndrome (98%) and had true bifurcation lesions (98%). TIMI-3 flow was established in 100% of the main branch and SB lesions. QCA revealed preservation ...
Background: The aim of our study is to determine the incidence of single coronary artery (SCA). SCA is a rarely seen coronary anomaly in which the right coronary artery and the left main coronary artery arise from single aortic sinus. Although SCA has a benign course in most cases and its clinical significance is unknown, in some autopsy studies it was shown to be related to sudden cardiac death.. Materials and methods: SCA patients detected among 215,140 coronary angiographies (CAG) performed between 1998 and 2013 in SANKO Hospital were included in our study. The classification of CAG was made according to the two different classifications defined by Smith and Lipton and colleagues.. Results: A total number of 215,140 patients who underwent routine CAG were included in the study, and SCA was detected in 67 (0.031%) patients. There were 6 (9%) type R-I, 23 (34%) type R-II, 10 (15%) type R-III, 16 (24%) type L-I and 12 (18%) type L-II patients according to the angiographic ...
TY - JOUR. T1 - Variation among cardiologists in the utilization of right heart catheterization at time of coronary angiography. AU - Malone, Michael L.. AU - Bajwa, Tanvir K.. AU - Battiola, Richard J.. AU - Fortsas, Michael. AU - Aman, Saleem. AU - Solomon, David J.. AU - Goodwin, James S.. PY - 1996/2. Y1 - 1996/2. N2 - To describe how often a right heart catheterization was performed at the time of coronary angiography, the patient characteristics that predicted the use of this procedure, and the variation among cardiologists in the use of this test, we reviewed all cases of coronary angiography (n = 1,282) during the first 2 mo of 1993 at two large community hospitals. Fifty-two percent of the cases received a right heart catheterization at the time of their coronary angiography. The following characteristics were associated with the receipt of a right heart catheterization in a logistic regression analysis: cardiomyopathy (odds ratio = 2.59, 95% Cl = 1.01, 6.62), congestive heart failure ...
LMT compression may occur in patients with PAH with severely dilated PAs and can be identified with either computed tomographic coronary angiography or selective coronary angiography (1). There are several reports of the safety of stent implantation and resolution of typical angina in such patients (1,2). In patients with LMT compression, atypical symptoms, and no evidence of rest ischemia, further testing is warranted to assess the physiological significance of the stenosis. This is relevant in this context because coronary blood flow and subendocardial perfusion are diastolic events (3,4), and LMT compression from an enlarged PA is a systolic event; hence, not all such lesions lead to ischemia. Exercise stress testing is relatively contraindicated in patients with severe PAH, and vasodilator stress nuclear testing may miss global ischemia in patients with left main disease. Thus, instantaneous wave-free ratio and fractional flow reserve are best suited for evaluating stenosis significance in ...
BACKGROUND: Conventional coronary angiography (CA) is still recommended before valvular surgery. Preliminary studies suggest that multislice spiral computed tomography coronary angiography (MSCT-CA) can be used to rule out coronary artery disease (CAD). AIM: To assess prospectively the safety of ruling out CAD before surgery solely on the basis of normal MSCT-CA in patients with severe aortic valve disease. METHODS: We included all consecutive patients scheduled for aortic valve surgery. We first estimated the calcium score (Agatston score equivalent [ASE]). Patients underwent injected MSCT if the ASE was|1000. CA was cancelled when MSCT-CA quality was sufficient and showed no significant CAD. Our primary endpoint was the occurrence of perioperative myocardial infarction in patients who underwent surgery with no prior CA. RESULTS: Between 1st July 2005 and 30th June 2008, we included 199 patients with severe aortic valve disease: 118 men (59%); mean age 69+/-12 years; 63 patients (32%) underwent CA
TY - JOUR. T1 - Sequential follow-up results of catheter intervention for coronary artery lesions after Kawasaki disease. T2 - Quantitative coronary artery angiography and intravascular ultrasound imaging study. AU - Ishii, Masahiro. AU - Ueno, Takafumi. AU - Ikeda, Hisao. AU - Iemura, Motofumi. AU - Sugimura, Tetsu. AU - Furui, Jun. AU - Sugahara, Yoko. AU - Muta, Hiromi. AU - Akagi, Teiji. AU - Nomura, Yuichi. AU - Homma, Tomoki. AU - Yokoi, Hiroyoshi. AU - Nobuyoshi, Masakiyo. AU - Matsuishi, Toyojiro. AU - Kato, Hirohisa. PY - 2002/6/25. Y1 - 2002/6/25. N2 - Background - The purpose of this study was to assess the sequential follow-up results of catheter intervention in Kawasaki disease by use of quantitative coronary angiography (QCA) and intravascular ultrasound imaging. Methods and Results - Catheter intervention was performed on 23 stenotic lesions in 22 patients (aged 2 to 24 years). Percutaneous balloon angioplasty (PBA) was performed in 4 patients, stent implantation in 7, ...
Quantitation of coronary luminal diameter with a 20 MHz mechanically rotating intravascular ultrasound (IVUS) catheter was compared with orthogonal-view cineangiography by use of a semiautomated edge-detection algorithm in 48 patients undergoing coronary angioplasty. Quantitative comparison of 196 matched segments was attempted, but in only 174 (88.8%) was a direct comparison of the two techniques possible. In angiographically normal coronary arteries (46 segments) the correlation between the values obtained by quantitative coronary angiography (QCA) and those achieved by IVUS was excellent (r = 0.92, p , 0.0001). For mild stenoses (80 segments) the correlation coefficient was only fair (r = 0.467, p , 0.001). After percutaneous transluminal coronary angioplasty the correlation coefficient between IVUS and QCA data (48 segments) was very weak (r = 0.282, p , 0.05). In conclusion, coronary IVUS is feasible and safe and even for a limited range of coronary arterial narrowing, significant ...
AIMS:. To investigate whether the use of intravascular ultrasound virtual histology (IVUS-VH) leads to any improvements in stent deployment, when performed in patients considered to have had an optimal percutaneous coronary intervention (PCI) by quantitative coronary angiography (QCA).. METHODS AND RESULTS:. After optimal PCI result (residual stenosis by QCA,30%), IVUS-VH was performed in 100 patients by protocol, with the option to use the information left to the discretion of the operators. Patients were categorised as: Group1 (n=54), where the IVUS-VH findings were used to evaluate the need for further optimisation of the stent deployment; and Group2 (n=46), where the IVUS-VH was documentary such that the stenting results were considered optimal according to QCA. Optimal stent deployment on IVUS-VH was defined as: normal stent expansion, absence of stent malapposition, complete lesion coverage as indicated by a plaque burden (PB%) between 30-40% and necrotic core confluent to the lumen,10% or ...
Unhealthy lifestyle factors such as smoking, obesity, inactivity and type 2 diabetes are endemic in the Middle East. The public health consequences might be detrimental; however, local studies on risk factors for coronary artery disease (CAD) are scarce. Patients referred for coronary angiography at a tertiary hospital in Amman, Jordan, between January and December 2015, were included in this study. Risk factors for CAD were assessed in a multivariate logistic regression model, and presented as odds ratio (OR) with 95% confidence interval (CI). Among 557 participants, 356 (63.9%) had CAD and 201 (36.1%) had a normal cardiogram. The majority (n = 395, 70.9%) were male, and median age was 55 years (interquartile range 47-64). Two-hundred-and-fifteen (38.6%) individuals reported previous diabetes, and 287 (51.5%) were current or previous smokers. In multivariate analysis, male gender (OR 3.7, 95% CI 2.3-6.0), age (45-54 years: OR 4.8, 95% CI 2.7-8.5; 55-64 years: OR 6.0, 95% CI 3.2-11.4; ≥65 years: OR 15
OBJECTIVES: The aim of the present study was to evaluate, in low-to-intermediate pre-test probability patients who were referred for coronary computed tomography angiography (CTA) and did not show obstructive coronary artery disease (CAD), whether an intramural course of a coronary artery is associated with worse outcome compared with patients without an intramural course of the coronary arteries. BACKGROUND: The prognostic value of an intramural course of the coronary arteries on coronary CTA in patients without obstructive CAD is not well-known. METHODS: The study population consisted of 947 patients with a low-to-intermediate pre-test probability who were referred for coronary CTA and who did not have obstructive CAD. During follow-up, the occurrence of unstable angina pectoris that required hospitalization, nonfatal myocardial infarction, and all-cause mortality was evaluated. Results : On coronary CTA, 210 patients (22%) had an intramural course of a coronary artery. The median depth of the ...
Background: Renal insufficiency plays a critical role in the pathogenesis of ischemic heart disease. The aim of the present study was to investigate the prevalence of renal dysfunction and its impact on prognosis in patients with left main coronary artery disease (LMCAD) and stable angina pectoris. Methods and Results: A total of 626 consecutive patients with significant coronary artery stenosis were enrolled. Renal insufficiency was graded using estimated glomerular filtration rate (eGFR) before coronary angiography. Chronic kidney disease (CKD) was defined as eGFR ...
Blockages prevent your heart from getting oxygen and important nutrients. This procedure is used to diagnose coronary heart disease and coronary microvascular disease after chest pain, sudden cardiac arrest, or abnormal results from tests such as an electrocardiogram (EKG) of the heart or an exercise stress test. It is important to detect blockages because over time they can cause chest pain, especially with physical activity or stress, or a heart attack. If you are having a heart attack, coronary angiography can help your doctors plan your treatment.. Cardiologists, or doctors who specialize in the heart, will perform coronary angiography in a hospital or specialized laboratory. You will stay awake so you can follow your doctors instructions, but you will get medicine to relax you during the procedure. You will lie on your back on a movable table. Often, coronary angiography is done with a cardiac catheterization procedure. For this, your doctor will clean and numb an area on the arm, groin or ...
CT Coronary Angiography Test Cost in Hyderabad. Packages starting for Angiogram test from Rs.12,500 at top hospitals. Compare quotes and book appointments online to avail discounts on Credihealth.
TY - JOUR. T1 - Feasibility of an automatic computer-assisted algorithm for the detection of significant coronary artery disease in patients presenting with acute chest pain. AU - Kang, Ki Woon. AU - Chang, Hyuk Jae. AU - Shim, Hackjoon. AU - Kim, Young Jin. AU - Choi, Byoung Wook. AU - Yang, Woo In. AU - Shim, Jee Young. AU - Ha, Jongwon. AU - Chung, Namsik. N1 - Funding Information: This work was supported by Industrial Strategic Technology Development Program, 10038419, Intelligent Image Diagnosis and Therapy-support System funded by the Ministry of Knowledge Economy (MKE, Republic of Korea).. PY - 2012/4. Y1 - 2012/4. N2 - Automatic computer-assisted detection (auto-CAD) of significant coronary artery disease (CAD) in coronary computed tomography angiography (cCTA) has been shown to have relatively high accuracy. However, to date, scarce data are available regarding the performance of auto-CAD in the setting of acute chest pain. This study sought to demonstrate the feasibility of an auto-CAD ...
In the past, two reliable methods leading to improvements in the accuracy of coronary angiography have been introduced. Interestingly, we demonstrated the first practical experience with intracoronary ultrasound more than a decade ago [5]. Since that time, virtual histology and optical coherence tomography have significantly improved our options for evaluation of coronary anatomy. Moreover, several studies have demonstrated that intravascular ultrasound guided interventions resulted in a reduced incidence of adverse clinical outcomes, especially in patients with proximal stenoses (left main coronary artery or proximal bifurcation lesions) [6]. On the other hand, evaluation of coronary anatomy and accurate morphology of coronary lesions have certain limitations, both with regard to hemodynamic significance and assessing the extent of ischemic myocardium, which is probably the key to choosing an optimal therapy. The only way currently to easily establish the hemodynamic significance of a ...
TY - JOUR. T1 - Usefulness of myocardial perfusion echocardiography to identify obstructive coronary artery disease in patients with abnormal ventricular septal motion. AU - Spevack, Daniel M.. AU - Shoyeb, Abu. AU - Yoon, Andrew J.. AU - Gordon, Garet M.. AU - Matros, Todd. AU - Reynolds, Harmony A.. AU - Shah, Alan. AU - Tunick, Paul A.. AU - Kronzon, Itzhak. PY - 2005/4/1. Y1 - 2005/4/1. N2 - Twenty-three patients who had septal wall motion abnormalities and who underwent angiography within 2 weeks were evaluated by myocardial perfusion echocardiography. Mean perfusion score (plateau video intensity times the wash-in rate) was lower in segments that were supplied by obstructed coronary arteries in real time (7.5 vs 22.6 dB/s, p ,0.005) and with end-systolic triggering (8.6 vs 20.9 dB/s, p ,0.001). Lower mean septal perfusion scores (,12 dB/s) were seen in 14 of 16 patients who had obstructive septal coronary artery disease, and normal mean septal perfusion scores were seen in 6 of 7 patients ...
Recent evidence suggests that higher restenosis rate is observed after coronary angioplasty of an infarct-related artery. Furthermore, angiographic restenosis seems associated with a deterioration of left ventricular function at follow-up. The aim of this study was to assess the acute results and angiographic restenosis following coronary artery stenting of infarct-related (Group 1) and non infarct-related coronary arteries (Group 2). We retrospectively analyzed the results of 381 consecutive patients treated with Palmaz-Schatz coronary stent implantation between May 1992 and January 1996. Stenting of the infarct-related artery was performed in 154 patients (Group 1), while 227 patients (Group 2) received stenting of the non infarct-related artery. Both groups had similar age, gender, clinical conditions and coronary angiographic pattern. There were no significant differences between groups, concerning type of stented coronary vessel (left anterior descending-LAD 52.4% vs non-LAD 47.6%, Group 1, ...
Health, ...23 May 2013 Paris France: Routinely measuring fractional flow reserv...The RIPCORD (Does routine pressure wire assessment influence managemen... Angiographic assessment of chest pain is flawed because it doesn...He explained that ischaemia is the most important determinant of clini...,Diagnostic,coronary,angiography:,Functional,flow,reserve,changes,decisions,in,25,percent,of,cases,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Objectives Our aim was to compare the effectiveness between right radial approach (RRA) and left radial approach (LRA) by means of a randomized study in a large unselected patient population undergoing diagnostic coronary angiography. Methods Totally, 1,000 patients were randomized to undergo to RRA (n = 500) or LRA (n = 500). Procedure success was defined as coronary angiography completed with the initial radial artery approach without changing to another route. Performance of the procedure: Total procedural duration, the number of catheters and guidewires used were recorded. Safety of the procedure: The parameters collected for radiation exposure were dose area product (DAP) and fluoroscopy time. Results The percentage of success was not different between the two aproaches (LRA, 94.0%; RRA,93.8%; P = 0.96). The crossover rate to femoral was low, accounting for 38 cases (3.8%), without differences between RRA and LRA (20 and 18 cases, respectively, P > 0.05). An almost triple incidence of ...
Hazy filling defect on coronary angiography: insights from optical coherence tomography Other Refereed Contribution to Refereed Journals ...
TY - JOUR. T1 - Prognostic value of combined CT angiography and myocardial perfusion imaging versus invasive coronary angiography and nuclear stress perfusion imaging in the prediction of major adverse cardiovascular events. T2 - The CORE320 multicenter study. AU - CORE320 Investigators. AU - Chen, Marcus Y.. AU - Rochitte, Carlos E.. AU - Arbab-Zadeh, Armin. AU - Dewey, Marc. AU - George, Richard T.. AU - Miller, Julie M.. AU - Niinuma, Hiroyuki. AU - Yoshioka, Kunihiro. AU - Kitagawa, Kakuya. AU - Sakuma, Hajime. AU - Laham, Roger. AU - Vavere, Andrea L.. AU - Cerci, Rodrigo J.. AU - Mehra, Vishal C.. AU - Nomura, Cesar. AU - Kofoed, Klaus F.. AU - Jinzaki, Masahiro. AU - Kuribayashi, Sachio. AU - Scholte, Arthur J.. AU - Laule, Michael. AU - Tan, Swee Yaw. AU - Hoe, John. AU - Paul, Narinder. AU - Rybicki, Frank J.. AU - Brinker, Jeffrey A.. AU - Arai, Andrew E.. AU - Matheson, Matthew B.. AU - Cox, Christopher. AU - Clouse, Melvin E.. AU - Di Carli, Marcelo F.. AU - Lima, João A.C.. N1 - ...
Lopid Coronary Angiography Trial". Atherosclerosis. 139 (1): 49-56. doi:10.1016/S0021-9150(98)00053-7. PMID 9699891. de Maat MP ... Ye S, Eriksson P, Hamsten A, Kurkinen M, Humphries SE, Henney AM (May 1996). "Progression of coronary atherosclerosis is ... such as progressive coronary atherosclerosis. The -1171 5A/6A variant has also been associated with congenital anomalies such ... "Effect of the stromelysin-1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis". The American ...
Leopold, Jane A.; Faxon, David P. (2018). "Diagnostic Cardiac Catheterization and Coronary Angiography". In Jameson, J. Larry; ... angiography or magnetic resonance (MR) angiography. After the catheter is removed, some pressure is applied to the incision ... Angiography is a medical imaging technique used to visualize the lumen of blood vessels. A catheter, which is a long and thin ... Angioplasty is a procedure used to widen narrowed blood vessels, especially in coronary arteries. A long and thin tube called ...
A comparison with thallium-201 and coronary angiography". Giornale Italiano di Cardiologia. 22 (7): 795-805. PMID 1473653. ... Gorlin R, Brachfeld N, MacLeod C. and Bopp P. Effect of nitroglycerin on the coronary circulation in patients with coronary ... If one is to evaluate ischemia (reductions in coronary blood flow resulting from coronary artery disease) then individuals must ... coronary aneurysm, wall motion abnormalities). Assessment of viable myocardium in particular coronary artery territory ...
"Transvenous Coronary Angiography in Humans using Synchrotron Radiation". Proc Natl Acad Sci USA. 83 (24): 9724-9728. Bibcode: ... including intravenous coronary arteriography. They devised a synchrotron radiation based imaging system which has been used ...
ISBN 978-0-7817-4524-6. Chassin MR, Kosecoff J, Solomon DH, Brook RH (1987). "How Coronary Angiography Is Used: Clinical ...
F. Mason Sones, (1943), cardiologist, inventor of coronary angiography. Enrique Pérez Santiago, first Puerto Rican hematologist ...
Chassin, M.R.; Kosecoff J.; Solomon D.H.; Brook R.H. (1987). "How Coronary Angiography Is Used: Clinical Determinants of ...
... such as coronary angiography, intravascular ultrasound or CT coronary angiography. For example, FFR takes into account ... The decision to perform a percutaneous coronary intervention (PCI) is usually based on angiographic results alone. Angiography ... January 2009). "Fractional flow reserve versus angiography for guiding percutaneous coronary intervention". N. Engl. J. Med. ... Fractional flow reserve (FFR) is a technique used in coronary catheterization to measure pressure differences across a coronary ...
"Urinary Bisphenol A Concentration and Angiography-Defined Coronary Artery Stenosis". PLOS ONE. 7 (8): e43378. Bibcode:2012PLoSO ... "Urinary Bisphenol A Concentration and Risk of Future Coronary Artery Disease in Apparently Healthy Men and Women". Circulation ...
CAST system is available for the detection of significant (>50%) coronary stenosis in coronary CT angiography (cCTA) studies. ... Halpern, EJ; Halpern, DJ (March 2011). "Diagnosis of coronary stenosis with CT angiography comparison of automated computer ... May 2010). "Automated computer-aided stenosis detection at coronary CT angiography: initial experience". Eur Radiol. 20 (5): ... of a computer-aided simple triage system for coronary CT angiography in patients with intermediate risk for acute coronary ...
Visipaque is commonly used as a contrast agent during coronary angiography. It is the only iso-osmolar contrast agent, with an ...
Coronary angiography is used to determine the patency and configuration of the coronary artery lumens. ... "Assessment of Agatston Coronary Artery Calcium Score Using Contrast-Enhanced CT Coronary Angiography". American Journal of ... Coronary CT calcium scanEdit. A coronary CT calcium scan is a computed tomography (CT) scan of the heart for the assessment of ... "Heart scan (coronary calcium scan)". Mayo Clinic. Retrieved 9 August 2015.. *^ a b Neves, Priscilla Ornellas; Andrade, Joalbo; ...
A Cath lab from Philips (Allura FC) provides coronary catheterization and angiography. Logistics and training were provided ... The University raised the number of beds to 700 and added a coronary care unit and intensive care unit facilities, as well as a ...
Also, ST elevation on EKG (see below) is more common in those patients with a cTnI > 1.5 µg/L. Coronary angiography in those ... The preferred NSAID is ibuprofen because of rare side effects, better effect on coronary flow, and larger dose range. Depending ...
Cardiac catheterization and coronary angiography are often performed to exclude ischemic heart disease.[citation needed] ... Coronary artery disease and high blood pressure may play a role, but are not the primary cause. In many cases the cause remains ...
According to Bokeria, the necessary medical procedures (coronary angiography and stenting) were "elementary". Bokeria said he ... Milošević should have been considered for a coronary bypass or angioplasty; while these operations might be rendered impossible ...
"NT-ProBNP independently predicts long-term mortality in patients admitted for coronary angiography". Angiology. 65 (1): 31-6. ... "Incremental prognostic value of C-reactive protein and N-terminal proB-type natriuretic peptide in acute coronary syndrome". ... typically increased in patients with asymptomatic or symptomatic left ventricular dysfunction and is associated with coronary ...
"Coronary Computed Tomography Angiography as a Screening Tool for the Detection of Occult Coronary Artery Disease in ... Coronary computed tomography angiography should not be used to screen people who are asymptomatic. Additionally, this test ... Coronary artery calcium scoring is a diagnostic test in the field of cardiovascular x-ray computed tomography. It is used to ... Asymptomatic people who have low risk, including a lack of family history of premature coronary artery disease, should not be ...
"Associations of Thyroid Hormones and Resting Heart Rate in Patients Referred to Coronary Angiography". Hormone and Metabolic ...
He died on 20 September 2015 after he had also undergone a coronary angiography. The cause of death was reported to be ...
... range independently predicts mortality in patients undergoing coronary angiography". Heart. 93 (4): 491-494. doi:10.1136/hrt. ... Coronary bypass surgery: If an enlarged heart is related to coronary artery disease, one may opt to have coronary artery bypass ... Many times this condition results from high blood pressure (hypertension) or coronary artery disease. An enlarged heart may not ... Non-lifestyle risk factors include a family history of cardiomegaly, coronary artery disease (CAD), congenital heart failure, ...
... range independently predicts mortality in patients undergoing coronary angiography". Heart. 93 (4): 491-494. doi:10.1136/hrt. ... Tracy, Richard Everett (2011). "Association of Cardiomegaly with Coronary Artery Histopathology and its Relationship to ...
Coronary Angiography, Interventional Cardiology and Cardiac surgery amongst other facilities are on the horizon. Encouraged by ...
Coronary artery bypass graft patency was studied through computed tomography angiography. 92% of patients were free from angina ... Hybrid coronary revascularization is a common procedure that takes advantage of coronary stenting in combination with CABG. ... Hybrid coronary bypass is a relatively new procedure and alternative to traditional bypass surgery that is defined by the ... Ruel M, Shariff M, Lapierre H, Goyal N, Sohmer B, McGinn J. Final Results of the Minimally Invasive Coronary Artery Bypass ...
A Clinical Study of Gadoteric Acid in Non-Coronary Magnetic Resonance (MR) Angiography Knör, S; Modlinger, A; Poethko, T; ...
... s on Coronary Computed Tomography Angiography-- Correlation with Intravascular Ultrasound and Fractional Flow ... of coronary blood flow occurs during systole and because myocardial bridging is a systolic event on angiography, its clinical ... Cardiac CT Angiography "Why Does Kyle Watson Keep Running? If He Stops, He'll Die". Runner's World. 5 September 2018. Rogers, ... A myocardial bridge (MB) is a congenital heart defect in which one of the coronary arteries tunnels through the heart muscle ...
"Normal and variant coronary arterial and venous anatomy on high-resolution CT angiography". AJR. American Journal of ... Heart attack Cardiac vessels Human heart with coronary arteries Heart coronary territories This article incorporates text in ... The name widow maker may also apply to the left coronary artery or severe occlusions to that artery. This term is used because ... Coronary arteries (labeled in red text) The arch of the aorta, and its branches. ...
He was taken to a hospital in Cayenne, French Guiana, where he received a coronary angiography. He was transferred to Fort de ...
The initiation of prasugrel before coronary angiography outside the context of primary PCI is not recommended. The drug was ... in people with acute coronary syndrome (ACS) who are to be managed with percutaneous coronary intervention (PCI). Prasugrel is ... Baker WL, White CM (2009). "Role of prasugrel, a novel P2Y(12) receptor antagonist, in the management of acute coronary ... November 2007). "Prasugrel versus clopidogrel in patients with acute coronary syndromes". The New England Journal of Medicine. ...
The main forms of cardiac CT scanning are: Coronary CT angiography (CCTA): the use of CT to assess the coronary arteries of the ... "Coronary Computed Tomography Angiography (CCTA)". Retrieved 2021-03-19. "Heart scan (coronary calcium ... "Assessment of Agatston Coronary Artery Calcium Score Using Contrast-Enhanced CT Coronary Angiography". American Journal of ... usually to diagnose coronary artery disease. Coronary CT calcium scan: also used for the assessment of severity of coronary ...
Main article: Angiography. Angiography is the use of fluoroscopy to view the cardiovascular system. An iodine-based contrast is ... Angiography is used to find aneurysms, leaks, blockages (thromboses), new vessel growth, and placement of catheters and stents ... It is also used in CT pulmonary angiography to decrease the required dose of iodinated contrast.[23] ... Contrast agents are required in conventional angiography, and can be used in both projectional radiography and computed ...
CT angiography. *Abdominal and pelvic CT *Virtual colonoscopy. *CT angiography *Coronary CT ...
Magnetic resonance angiography and duplex ultrasonography appear to be slightly more cost-effective in diagnosing peripheral ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... artery disease among people with intermittent claudication than projectional angiography.[3] Treatment[edit]. Exercise can ...
Coronary artery angioscopy, which first was used to reveal the presence of a blood clot in the coronary arteries of patients ... Angiography. *Digital subtraction angiography *Cerebral angiography. *Aortography. *Fluorescein angiography. *Radionuclide ... Forrester JS, Litvack F, Grundfest W, Hickey A (1987). "A perspective of coronary disease seen through the arteries of living ...
Multidetector coronary CT angiography has been indicated as a single competent diagnostic imaging tool capable of delineating ... a b Douglas, H., Moore, M., & Purvis, J. (2012). Comprehensive assessment of a quadricuspid aortic valve and coronary arteries ... and abnormal displacement of the ostium in the right coronary artery in association with QAV.[4][6] Some research has shown ... valvular anatomy, severity of regurgitation, and high risk coronary problems.[6] Classification[edit]. There have been seven ...
CT angiography. *Abdominal and pelvic CT *Virtual colonoscopy. *CT angiography *Coronary CT ...
CT angiography. *Abdominal and pelvic CT *Virtual colonoscopy. *CT angiography *Coronary CT ...
CT angiography *Coronary. *Pulmonary. *Computed tomography of the head. *Quantitative computed tomography ...
"How Coronary Angiography Is Used: Clinical Determinants of Appropriateness". JAMA. 258 (18): 2543-47. doi:10.1001/jama.258.18. ...
Computed tomography angiography, magnetic resonance angiography, invasive angiography. Treatment. Anticoagulation, angioplasty ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... MR angiography). They use smaller amounts of contrast and are not invasive. CT angiography and MR angiography are more or less ... The gold standard is cerebral angiography (with or without digital subtraction angiography).[3][14][15] This involves puncture ...
Chandra P, Cribier A, Seth A (1995). "Utility of Pilot wire in angioplasty of tortuous and highly angulated coronary arteries ... "Society of the Cardiac Angiographies and Intervention". 2015. Retrieved 3 February 2015.. ... Chandra P, Cribier A, Seth A (1995). "Utility of Pilot wire in angioplasty of tortuous and highly angulated coronary arteries ... Percutaneous Coronary Interventions Without On-Site Surgical Backup.[2] He is a member of the expert committee of the ...
CT angiography. *Abdominal and pelvic CT *Virtual colonoscopy. *CT angiography *Coronary CT ...
Comparison of computed tomography angiography with digital subtraction angiography in the assessment of clipped intracranial ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... CT Angiography and MR Angiography for Detection-Prospective Blinded Comparison in a Large Patient Cohort". Radiology. 219 (3): ... Once suspected, intracranial aneurysms can be diagnosed radiologically using magnetic resonance or CT angiography.[16] But ...
After percutaneous coronary interventions (PCIs), such as the placement of a coronary artery stent, a U.S. Agency for ... Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and ... Hall SL, Lorenc T (February 2010). "Secondary prevention of coronary artery disease". American Family Physician. 81 (3): 289-96 ... March 2009 recommendations from the USPSTF on the use of aspirin for the primary prevention of coronary heart disease encourage ...
Coronary CT angiography (CTA): the use of CT to assess the coronary arteries of the heart. The subject receives an intravenous ... "Assessment of Agatston Coronary Artery Calcium Score Using Contrast-Enhanced CT Coronary Angiography". American Journal of ... Coronary CT calcium scan: also used for the assessment of severity of coronary artery disease. Specifically, it looks for ... Main article: Computed tomography angiography. Computed tomography angiography (CTA) is contrast CT to visualize arterial and ...
However, in Takayasu's arteritis, where the aorta may be involved, it is unlikely a biopsy will be successful and angiography ... Usually in children(age,4), it affects large, medium, and small vessels, prominently the coronary arteries. Associated with a ... Patients have CNS symptoms as well as cerebral vasculitis by angiography and leptomeningeal biopsy. ...
venae cavae, coronary sinus) → right atrium (atrial appendage, fossa ovalis, limbus of fossa ovalis, crista terminalis, valve ... "Characterisation of the normal right ventricular pressure-volume relation by biplane angiography and simultaneous ... of inferior vena cava, valve of coronary sinus) → tricuspid valve → right ventricle (infundibulum, moderator band/septomarginal ...
... low-dose coronary CT angiography, nuclear imaging, and X-ray angiography), differences in the mechanism by which this damage ...
Hall, SL; Lorenc, T. Secondary prevention of coronary artery disease. American family physician. 2010-02-01, 81 (3): 289-96. ... Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and ... Aspirin Resistance in Patients with Stable Coronary Artery Disease with and without a History of Myocardial Infarction. Annals ... National Guideline Clearinghouse (NGC). 2011 ACCF/AHA/SCAI guideline for percutaneous coronary artery intervention. A report of ...
If unmatched perfusion defects are found, further evaluation by CT pulmonary angiography, right heart catheterization, and ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ...
... coronary computed tomographic angiography(英语:coronary computed tomographic angiography), coronary angiogram(英语:Coronary ... Coronary heart disease. NIH. [15 September 2013].. *^ 4.0 4.1 4.2 4.3 4.4 What Are the Signs and Symptoms of Coronary Heart ... 冠狀動脈疾病(英语:coronary artery disease, CAD)又稱為缺血性心臟病或簡稱冠心病(英语:ischemic heart disease, IHD)[13]、冠狀動脈粥狀硬化心臟病[14]、冠狀動脈粥狀硬化心血管疾病(英语: ... coronary atherosclerotic heart disease, CAHD)[
CT angiography. *Abdominal and pelvic CT *Virtual colonoscopy. *CT angiography *Coronary CT ... Redistribution indicates the existence of coronary steal and the presence of ischemic coronary artery disease.[5] ... Exercise or dipyridamole induces widening (vasodilation) of normal coronary arteries. This produces coronary steal from areas ...
CT angiography *Coronary. *Pulmonary. *Computed tomography of the head. *Quantitative computed tomography ...
To generate an image of the cardiovascular system, including the arteries and veins (angiography) an initial image is taken of ... Examples include cardiac catheterization (to examine for coronary artery blockages) and barium swallow (to examine for ... Roobottom CA, Mitchell G, Morgan-Hughes G (2010). "Radiation-reduction strategies in cardiac computed tomographic angiography ...
... especially when given via the arteries prior to studies such as catheter coronary angiography. Non-ionic contrast agents, which ...
2007). "Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary ... Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ...
Angiography[mag-edit , alilan ya ing pikuwanan]. Angiogram of the coronary arteries. ... Coronary artery bypass surgery[mag-edit , alilan ya ing pikuwanan]. Pun bulung: Coronary artery bypass graft surgery ... Coronary artery bypass surgery during mobilization (freeing) of the right coronary artery from its surrounding tissue, adipose ... Thrombus material (in a cup, upper left corner) removed from a coronary artery during a percutaneous coronary intervention to ...
Fluoroscopy and angiography are special applications of X-ray imaging, in which a fluorescent screen and image intensifier tube ... coronary or other arteries. ...
CT angiography. *Abdominal and pelvic CT *Virtual colonoscopy. *CT angiography *Coronary CT ...
Fluoroscopy and angiography are special applications of X-ray imaging, in which a fluorescent screen and image intensifier tube ... coronary or other arteries. ...
... coronary Coronary angiography is an X-ray of the heart and blood vessels of a living patient. The X-ray is taken with a moving ... camera, which produces a very detailed and accurate picture of the condition of the coronary arteries. ... Angiography, Coronary Medical Discoveries COPYRIGHT 1997 Thomson Gale. Angiography, coronary. Coronary angiography is an X-ray ... coronary angiography (ko-rŏn-er-i) n. see angiography. Cite this article Pick a style below, and copy the text for your ...
Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the ... Cardiac angiography; Angiography - heart; Angiogram - coronary; Coronary artery disease - angiography; CAD - angiography; ... Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the ... Coronary angiography is often done along with cardiac catheterization. This is a procedure that measures pressures in the heart ...
Interventional X-ray coronary angiography is a primary tool to guide catheter-based coronary interventions. High-quality images ... Interventional X-ray coronary angiography is a primary tool to guide catheter-based coronary interventions. High-quality images ... Committee on Coronary Angiography). Developed in collaboration with the Society for Cardiac Angiography and Interventions. J Am ... ACC/AHA guidelines for coronary angiography. A report of the American College of Cardiology/American Heart Association Task ...
Find out why coronary angiography is used. What happens during coronary angiography?. During the procedure a long, thin, ... After coronary angiography. Youll usually be able to leave hospital on the same day you have a coronary angiography, after a ... The resulting images are known as coronary angiograms or arteriograms.. Why do I need coronary angiography?. Coronary ... Coronary angiography is also considered to be the best method of diagnosing coronary heart disease, where a build-up of fatty ...
NICE guideline 95 proposes using CT coronary angiography (CTCA) in patients at low predicted risk of coronary artery disease ... CT coronary angiography leads to more accurate detection of coronary artery disease, fewer second-line investigations and more ... CT coronary angiography (CTCA) is a highly effective first-line investigation in those patients assessed to be at low- ... CT coronary angiography (CTCA) outperformed exercise tolerance testing (ETT) for each of the comparative measures described ...
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CORONARY ANGIOGRAPHY venothini My mother has small pain in below chest and back of chest, then doctor advise to go for an ... CORONARY ANGIOGRAPHY. My mother has small pain in below chest and back of chest, then doctor advise to go for an angiogram, ...
Coronary angiography shows if you have CAD. Most of the time, the coronary arteries cant be seen on an x ray. During coronary ... Coronary angiography (an-jee-OG-ra-fee) is a test that uses dye and special x rays to show the inside of your coronary arteries ... The coronary arteries supply blood and oxygen to your heart. A material called plaque can build up on the inside walls of the ... angiography, a special dye is injected into the bloodstream to make the coronary arteries show up on an x ray. ...
Coronary Angiography. Its Role in the Management of the Patient with Angina Pectoris. HAROLD A. BALTAXE, DAVID C. LEVIN ... The history, technic, and complications of coronary angiography have been discussed. Myocardial infarction caused by the ...
coronary angiography Also called coronary angiogram, coronary angiography is an X-ray test to diagnose diseases of the arteries ... Coronary angiography can detect weakened blood vessel walls and narrowed or blocked vessels. X-rays are taken after a special ...
... Coronary CT Angiography Dobutamine Echocardiogram Doppler Ultrasound Echocardiogram in Congestive Heart ... These images are a random sampling from a Bing search on the term "Coronary Angiography." Click on the image (or right click) ... Diastolic Heart Failure Kawasaki Disease Coronary CT Angiography Cardiac Imaging Cancer Risk due to Diagnostic Radiology Post- ... Angioplasty Aortic Angiography Apical Four Chamber Echocardiogram View Cardiac CT Calcium Scoring Cardiac Imaging Cardiac MRI ...
RCA: right coronary artery.. b: Conventional selective coronary angiography of the same patient, in the LAO orientation, ... 2 Dill T, Dix WR, Hamm CW, Jung M, Kupper W, Lohman M, Reime B, and Ventura R 1998 Intravenous coronary angiography with ... 8 Ohtsuka S, Sugishita Y, Takeda T, Itai Y, Tada J, and Hyodo K, 1999 Dynamic intravenous coronary angiography using 2D ... 11 Thomlinson W 1995 Transvenous Coronary Angiography in Humans Biomedical Applications of Synchrotron Radiation (E Burattini ...
... compared favorably with conventional angiography in predicting probable coronary disease -- but its accuracy varied widely ... CT coronary angiography (CTCA) compared favorably with conventional angiography in predicting probable coronary disease -- but ... stenosis by conventional coronary angiography.. As compared with conventional angiography, CTCA had a PPV of 91.6% and NPV of ... Source Reference: Diamond GA, Kaul S "Gone fishing! On the real-world accuracy of computed tomography coronary angiography" ...
Coronary Computed Tomographic Angiography: A Rapid Alternative to Usual Care. Coronary computed tomographic (CT) angiography ( ... Coronary artery disease detected by coronary CT angiography is associated with intensification of preventive medical therapy ... Coronary computed tomographic angiography (CTA) demonstrating nonobstructive coronary artery disease. Top row, Three- ... Prognostic value of nonobstructive and obstructive coronary artery disease detected by coronary computed tomography angiography ...
... , CT Coronary Angiogram, CT Angiography of Coronary Vessels, Coronary CT Angiogram, CCTA, Computed ... Tomographic Angiography of Coronary Arteries, CT Angiography of Coronary Arteries. ... Coronary CT Angiography. Aka: Coronary CT Angiography, CT Coronary Angiogram, CT Angiography of Coronary Vessels, Coronary CT ... Coronary CT Angiography (CCTA) Image quality compared with Angiography. *Standard angiography (gold standard). *Temporal ...
118 Repeat Coronary Angiography in Patients with Previously Normal Coronary Arteries Vitaliy Androshchuk, Majd Protty, Phillip ... 28 Complication rate of coronary angiography in patients with prior coronary artery bypass grafting Perin Celebi, Mohamad Fahed ... 133 Although CT Coronary Angiography in the West of Scotland is Used in a Higher Risk Population than Recommended by Nice, The ... Coronary angiography in worsening heart failure: determinants, findings and prognostic implications João Pedro Ferreira, ...
... is a noninvasive method to image the coronary arteries. Applications include the following: Diagnosis of coronary artery ... Gorenoi V, Schönermark MP, Hagen A. CT coronary angiography vs. invasive coronary angiography in CHD. GMS Health Technol Assess ... Coronary CT Angiography Q&A What are the applications of coronary computed tomography angiography (CCTA)?. Updated: Dec 21, ... Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. J Am ...
Gorenoi V, Schönermark MP, Hagen A. CT coronary angiography vs. invasive coronary angiography in CHD. GMS Health Technol Assess ... Coronary CT Angiography Q&A How are patients prepared for coronary computed tomography angiography (CCTA)?. Updated: Dec 21, ... Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. J Am ... Next generation coronary CT angiography: in vitro evaluation of 27 coronary stents. Eur Radiol. 2014 Nov. 24(11):2953-61. [ ...
The appropriateness of coronary angiography and coronary artery bypass surgery in the Trent regional health authority was ... The appropriateness of coronary angiography and coronary artery bypass surgery in the Trent regional health authority was ... Audit of Coronary Angiography and Bypass Surgery. by D. Gray, John R. Hampton, Steven J. Bernstein, Jacqueline Kosecoff, Robert ... Forty-nine percent of coronary angiographies were considered to be entirely appropriate in relation to the patients clinical ...
Intravascular Contrast-Enhanced Coronary MR Angiography: Relationship Between Coronary Artery Delineation and Blood T1, J. ... Evaluation of 3D Magnetic Resonance Coronary Angiography with Clariscan in Humans: Correlation with X-Ray Angiography, R.M. ... Coronary MR Angiography. Hall C. Thursday: 13:30 15:30. 1624. A Computationally Efficient Algorithm for Accurate Detection of ... Spiral Coronary Angiography Using the Intravascular Contrast Agent NC100150 Injection, E.M. Pedersen, M. Pedersen, J. Rickers, ...
Left heart cath or Coronary angiography only?. By rap55 in forum Cardiology ... Left heart catheterization with coronary angiography, left ventriculography, angioplasty, carotid arch and four vessels, ... LT Heart Cat and Coronary LT Angiography. By Trendale in forum Cardiology ... L heart cath w/ r coronary angio???. By sholland1 in forum Cardiology ...
4. RIGH CORONARY ARTERY: The right coronary artery is a large, dominant vessel. The distal right coronary artery has a discrete ... We used a JR4 catheter to cannulate the right coronary artery.. RESULTS OF SELECTIVE CORONARY ANGIOGRAM:. 1. LEFT MAIN: The ... LT Heart Cat and Coronary LT Angiography. By Trendale in forum Cardiology ... RESULTS OF ANGIPLASTY AND STENTING OF THE RIGHT CORONARY ARTERY:. EQUIPMENT USED:. 1. 6-French JR4 guider.. 2. Cougar wire.. 3 ...
... coronary CT angiography constructs a 3-D picture of the arteries which can show the if any material such as plaque has built up ... Coronary CT Angiography (CCTA). UPMC Content 2. Coronary CT angiography imaging uses computed tomography (CT) to look at the ... What Is Coronary CT Angiography (CCTA)?. Coronary CT angiography uses a special computer to take multiple pictures of the heart ... Coronary CT Angiography Results. Common results of a coronary CT include:. *Normal results typically mean that the arteries ...
Contrast-media induced nephropathy in patients undergoing coronary angiography.. Gomes VO1, Blaya P, Poli de Figueiredo CE, ...
... including coronary artery disease (CAD), plaque buildup, and consequent narrowing of the coronary arteries. CCTA is not ... Coronary computerized tomography angiography (CCTA) is a heart scan or imaging test that helps diagnose heart conditions, ... Coronary computerized tomography angiography (CCTA) is a heart scan or imaging test that helps diagnose plaque buildup and ... home/heart center/ heart a-z list/ how is a ct coronary angiography done center ...
Coronary arteries were cannulated, namely the anterior interventricular artery, the circumflex branch of the left coronary ... These steps were repeated for each coronary vessel and under experimentally simulated coronary heart disease. Thermal imaging ... Detection of coronary thrombosis after multi-phase postmortem CT-angiography. Leg Med (Tokyo) 15:12-18CrossRefGoogle Scholar ... allowed a clear representation of the morphology and course of the coronary vessels and of experimentally simulated coronary ...
Although the rates of invasive coronary angiography and coronary revascularization were higher in the CTA group than in the ... without resulting in a significantly higher rate of coronary angiography or coronary revascularization. (Funded by the Scottish ... Coronary CT Angiography and 5-Year Risk of Myocardial Infarction.. SCOT-HEART Investigators, Newby DE, Adamson PD, Berry C, ... Coronary CT Angiography and Subsequent Risk of Myocardial Infarction. [N Engl J Med. 2019] ...
Coronary angiography revealed neither spastic occlusion nor significant narrowing of coronary arteries. ... Conventional Coronary Angiography Induced Takotsubo Cardiomyopathy Complicated with Cardiac Tamponade. Min Gyu Kang,1 Kye-Hwan ... We hereby report the case of a 70-year-old woman who underwent coronary angiography with an ergonovine provocation test to ... Figure 1: (a) Coronary angiography showed atherosclerotic change with mild stenosis in the left anterior descending artery. (b ...
If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patients written consent to publication and send them to the editorial office before submitting your response [Patient consent forms] ...
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  • What are the applications of coronary computed tomography angiography (CCTA)? (
  • Coronary computed tomography angiography (CCTA) is a noninvasive method to image the coronary arteries. (
  • How are patients prepared for coronary computed tomography angiography (CCTA)? (
  • Coronary computerized tomography angiography (CCTA) is a heart scan or imaging test that helps diagnose plaque buildup and consequent narrowing of the coronary arteries. (
  • Coronary CT angiography (CTA or CCTA) is the use of computed tomography (CT) angiography to assess the coronary arteries of the heart. (
  • Coronary CT angiography (CCTA) may resolve the spotty accuracy in. (
  • The coronary CT angiography (CCTA) takes 64-cross-section images of the heart with each rotation and is fast enough to take motion-free images that are sharper and more detailed than ever before. (
  • The CCTA is consistently able to rule out significant narrowing of the major coronary arteries, and can also non-invasively detect "soft plaque," or fatty matter, in the artery walls that has not yet hardened but that may lead to future problems. (
  • Recently conducted clinical studies prove the utility of Coronary Computed Tomography Angiography (CCTA) as a viable alternative to invasive angiography for the detection of Coronary Artery Disease (CAD). (
  • In this paper, we propose a fast and fully automatic system that is capable of detecting, grading and classifying coronary stenoses in CCTA caused by all types of plaques. (
  • Coronary CT Angiography (CCTA) is a new exam that creates detailed 3-D images of the heart and arteries in a matter of just seconds. (
  • AbstractPurpose of ReviewTo provide an overview of recent studies of coronary computed tomography angiography (CCTA) and how it has helped to improve clinical outcomes for patients presenting with chest pain.Recent FindingsRandomised controlled trials have uniformly demonstrated that the use of CCTA is associated with improvements in patient diagnosis, management and treatments as well as the avoidance of unnecessary invasive coronary angiography. (
  • CCTA might be considered to be the first test of choice for the investigation of coronary heart disease. (
  • Coronary computed tomographic angiography (CCTA) is a rapidly evolving test for diagnosis of coronary artery disease. (
  • Although invasive coronary angiography is the gold standard for coronary artery disease (CAD), CCTA is an excellent noninvasive tool for evaluation of chest pain. (
  • CCTA is also helpful in the detection of subclinical and vulnerable coronary plaques. (
  • HealthDay)-Noninvasive coronary computed tomography angiography (CCTA) is a reliable alternative to coronary angiography for detection of cardiac allograft vasculopathy (CAV), according to a meta-analysis published online March 26 in the Journal of the American College of Cardiology . (
  • Omar Wever-Pinzon, M.D., from the University of Utah Health Sciences Center in Salt Lake City, and colleagues compared the diagnostic accuracy of CCTA with conventional coronary angiography (CCAG) alone or with intravascular ultrasound (IVUS) for detecting CAV. (
  • CCTA using currently available technology is a reliable noninvasive imaging alternative to coronary angiography with an excellent sensitivity, specificity, and negative predictive value for the detection of CAV," the authors write. (
  • We assessed the ability of coronary computed tomography angiography (CCTA) to detect CAD in diabetic patients and to predict subsequent cardiac events. (
  • By virtue of its ability to detect both coronary stenoses and calcified and noncalcified plaques, coronary computed tomography angiography (CCTA) may be a reasonable option to close this diagnostic gap. (
  • During the last few years, CCTA has emerged as a widely used imaging modality for detection or exclusion of obstructive CAD, replacing invasive coronary angiography in certain conditions ( 5 ). (
  • It is unclear whether an evaluation incorporating coronary computed tomographic angiography (CCTA) is more effective than standard evaluation in the emergency department in patients with symptoms suggestive of acute coronary syndromes. (
  • In this multicenter trial, we randomly assigned patients 40 to 74 years of age with symptoms suggestive of acute coronary syndromes but without ischemic electrocardiographic changes or an initial positive troponin test to early CCTA or to standard evaluation in the emergency department on weekdays during daylight hours between April 2010 and January 2012. (
  • In patients in the emergency department with symptoms suggestive of acute coronary syndromes, incorporating CCTA into a triage strategy improved the efficiency of clinical decision making, as compared with a standard evaluation in the emergency department, but it resulted in an increase in downstream testing and radiation exposure with no decrease in the overall costs of care. (
  • The use of CCTA led to the diagnosis of coronary artery disease - a radiologic diagnosis of unclear value - in 1 of 20 additional patients. (
  • In patients with acute chest pain deemed at low to intermediate risk of acute coronary syndrome, CCTA has been shown by several randomized, controlled trials to be efficacious and cost-effective, demonstrating high sensitivity and high negative predictive value. (
  • In the present case, CCTA enabled rapid diagnosis of coronary artery disease, and showed that the extent of disease was limited to a single vessel not readily amenable to percutaneous intervention. (
  • What is the impact of coronary computed tomography (CCTA) on utilization of invasive coronary angiography, institution of preventive medication, and clinical outcomes? (
  • CCTA revealed normal coronary arteries in 654 (37%), mild nonobstructive disease in 372 (21%), intermediate nonobstructive in 300 (17%), and obstructive in 452 (25%) of study subjects. (
  • A strategy of early CCTA leads to more appropriate use of invasive angiography, modification of preventive medical therapy, and a reduction in fatal and nonfatal myocardial infarction compared to standard care. (
  • The results of this study confirm a role for CCTA in the early initial evaluation of patients presenting with angina and suspected coronary artery disease. (
  • A major conclusion from this study is that early CCTA results in a more appropriate utilization of invasive coronary arteriography and a more aggressive approach to medical management of patients with angina, presumably because of demonstration of a significant atherosclerotic burden on CCTA. (
  • Single-center studies have yielded good results, leading to increased referrals for patients who otherwise would have undergone invasive angiography, the authors noted. (
  • Visual and automatic grading of coronary artery stenoses with 64-slice CT angiography in reference to invasive angiography. (
  • In some cases, CTA can replace invasive angiography done by cardiac catheterization, particularly in those patients who are at low to moderate risk for CAD. (
  • The test is somewhat less specific, however, so a positive result is less conclusive and may need to be confirmed by subsequent invasive angiography. (
  • Both coronary CT angiography and invasive angiography via cardiac catheterization yield similar diagnostic accuracy when both are being compared to a third reference standard such as intravascular ultrasound or fractional flow reserve. (
  • For all scanner generations, the spatial resolution is lower than that of invasive angiography, making analysis of smaller side branches and distal vessel segments impossible--in most studies, analysis was limited to segments of ≥1.5 mm in diameter. (
  • While invasive angiography will remain the clinical gold standard for coronary artery visualization for the foreseeable future, CT imaging has some potential advantages over invasive angiography. (
  • and many issues--such as the patient's heart rate, body weight, or ability to perform a breath-hold, as well as contraindications to contrast or problems with vascular access (which may make invasive angiography more prone to complication)--will play a role in the decision-making process. (
  • If the suspicion of disease requiring intervention is high then invasive angiography is preferred at present because angioplasty if indicated can be done in the same sitting and an angiogram will not have to be repeated. (
  • When cardiologists talk about coronary angiography, they usually mean conventional invasive angiography. (
  • Coronary angiography is often done along with cardiac catheterization . (
  • Developed in collaboration with the Society for Cardiac Angiography and Interventions. (
  • Cardiac catheterisation and coronary angiography are usually very safe. (
  • If used appropriately it can lead to rapid rule-out of coronary artery disease in patients with non-cardiac chest pain, fewer second-line investigation and overall reduced cost to reach diagnosis. (
  • To deliver the dye to your coronary arteries, a procedure called cardiac catheterization (KATH-e-ter-i-ZA-shun) is used. (
  • 102 Early Angiography and Coronary Intervention in Comatose Survivors of Out of Hospital Cardiac: Can the 12-lead ECG be Gatekeeper? (
  • 1625. Selected the Optimal Period of Diastole for Eliminating Cardiac Motion in Coronary MRA by the Use of an ECG-Triggered Navigator Echo Technique, Y. Wang, R. Watts, J. Bezenson, I. Mitchell, T. Ngyen and M. Prince, Weill Medical College of Cornell University, New York, NY, USA. (
  • CTA is superior to coronary CT calcium scan in determining the risk of Major Adverse Cardiac Events (MACE). (
  • It may be useful in the diagnosis of suspected coronary heart disease, for follow-up of a coronary artery bypass, for the evaluation of valvular heart disease and for the evaluation of cardiac masses. (
  • At present, it appears that the greatest utility of cardiac CT lies in ruling out coronary artery disease rather than ruling it in. (
  • This means for every 100 patients who appear to have coronary artery disease after CT angiography, 18 of them actually won't have it, and that for every 100 patients who have a negative CT angio test result (i.e. the test says they do not have coronary artery disease), 7 will actually have the disease as defined by the reference standard of invasive coronary angiography via cardiac catheterization. (
  • Because the heart is effectively imaged more than once (described above), cardiac CT angiography can result in a relatively high radiation exposure (around 12 millisievert), although newer acquisition protocols, have recently been developed which drastically reduce this exposure to around 1 mSv (cfr. (
  • Cardiac arrhythmias, coronary artery stents and tachycardia may result in a reduced image quality. (
  • With the advent of subsecond rotation combined with multi-slice CT (up to 320 slices), high resolution and high speed can be obtained at the same time, allowing excellent imaging of the coronary arteries (cardiac CT angiography). (
  • We hereby report the case of a 70-year-old woman who underwent coronary angiography with an ergonovine provocation test to evaluate recurrent chest pain and was readmitted 7 days later presenting with TCM, followed by left ventricular outflow tract obstruction and cardiac tamponade. (
  • In this report, we present an unusual case of TCM induced by coronary angiography (CAG) with an ergonovine provocation test that was complicated with cardiac tamponade. (
  • The patient was transferred to a cardiac catheter laboratory, but there was neither occlusion nor significant narrowing on coronary arteries (Figure 2 ). (
  • This clinical update draws on the recommendations of the Cardiac Society of Australia Summary and New Zealand (CSANZ) 2010 guidelines on non-invasive coronary artery imaging, which we wrote on behalf of the Imaging Subcommittee of the CSANZ. (
  • The study population consisted of 539 consecutive patients with diabetes who presented to our outpatient clinic or were admitted to our hospital for cardiac evaluation (exercise electrocardiogram, stress echocardiography, or invasive coronary angiography) because of suspected CAD (new-onset chest pain, abnormal stress test, multiple cardiovascular risk factors including diabetes) between January 2006 and September 2007. (
  • Coronary CTA may be appropriate for patients with atypical symptoms and an intermediate risk for CAD, those with inconclusive stress test results, or those who are considering cardiac catheterization. (
  • The gold standard test for the diagnosis of coronary artery disease (CAD) is cardiac catheterization. (
  • According to 1990 registry data from the Society for Cardiovascular Angiography and Interventions, the total rate of complications during diagnostic cardiac catheterization was 1.77%, including death, myocardial infarction, arrhythmia, neurological complications, vascular complications, and adverse reactions to contrast medium. (
  • If the heart muscle has been damaged, then a cardiac ultrasound (echocardiograph) is of great help in diagnosing coronary heart disease along with MSCT (multi-slice computed tomography) of the coronary arteries. (
  • Cardiac CT Angiography can detect blockages even before symptoms occur. (
  • Cardiac CT Angiography takes pictures of the heart and its arteries to help determine if there are blockages, which - If left untreated - can lead to fatigue, shortness of breath, chest pain and even heart attack. (
  • In the past, the only way to make similar diagnoses was to perform a cardiac catheterization, an invasive procedure that requires a catheter, or small tube, to be threaded into the coronary arteries. (
  • Factors including gender, age, height, weight, transversal cardiac diameter (TCD), transversal thoracic diameter (TTD), heart rate (HR), body surface area (BSA = [weight × height/3600](1/2)) and cardiothoracic ratio (CTR = TCD/TTD) were recorded, measured and calculated before administration of contrast media during coronary CT angiography. (
  • If the coronary artery is blocked or narrowed using a cardiac angiography, it is also important to figure out how much percent blocked or narrowed that artery is. (
  • The same preps apply for thoracic aorta with coronary angiography, pulmonary vein mapping, cardiac anatomic structure studies and valve replacement planning imaging. (
  • COACT Trial: Does Immediate Coronary Angiography After Cardiac Arrest Improve Survival? (
  • A total of 61.4% of patients in the immediate angiography group and 64.0% of patients in the delayed group were alive 1 year post-cardiac arrest. (
  • Immediate coronary angiography after cardiac arrest did not improve survival at 1 year compared with a strategy of delayed procedure in patients successfully resuscitated from out of hospital cardiac arrest (OHCA) in the absence of ST segment elevation (STE), investigators in the Netherlands reported at the American Heart Association (AHA) 2019 Scientific Sessions in Philadelphia. (
  • Towards transparency in cardiac radiology: should CT coronary angiography radiation doses be published? (
  • Coronary ischemia, myocardial ischemia, or cardiac ischemia, is a medical term for a reduced blood flow in the coronary circulation through the coronary arteries. (
  • If blood flow through the coronary arteries is stopped completely, cardiac muscle cells may die, known as a myocardial infarction, or heart attack. (
  • Plaques in the walls of the coronary arteries can rupture, resulting in occlusion of the artery and deprivation of blood flow and oxygen to the heart muscle, resulting in cardiac cell death. (
  • Watch this video to find out what to expect when having a coronary angiogram. (
  • Also called coronary angiogram, coronary angiography is an X-ray test to diagnose diseases of the arteries that supply blood to the heart. (
  • How Much Does a Coronary CT Angiogram Cost? (
  • These findings are in excellent agreement with the conventional selective coronary angiogram performed a few hours later in the hospital cardiology unit ( Figure 9b ). (
  • A CT coronary angiogram is a test used to measure the blood flow through the coronary arteries, where an iodine-based dye is injected into the bloodstream to highlight the vessels. (
  • D espite the various functional tests and biomarkers available for evaluation of patients with coronary artery disease (CAD), we sometimes look for the reassurance of anatomical information by way of a coronary angiogram. (
  • The detailed description and angiographic presentation of coronary atherosclerosis and collateral pathways, as well as their effect on the left ventricular angiogram, are highlights of the book. (
  • The purpose of this study is to test the ability of a new X-ray technique called CT angiography to identify significant narrowing of the coronary arteries compared to traditional coronary angiogram. (
  • In patients with a high pretest likelihood of disease, performing an invasive, catheter-based coronary angiogram will often be much more appropriate because it offers the option of immediate treatment. (
  • In this way, atherosclerotic plaque can become visible, which is undetectable in the invasive coronary angiogram (Figure 1). (
  • 2,11,12 The aim is to avoid an otherwise necessary invasive coronary angiogram if CT shows the absence of clinically relevant CAS. (
  • FFR led to a change in the judgement of whether a coronary artery had a 'significant' lesion in 64 patients (32%) compared to angiogram alone. (
  • When the dye flows from the aorta to the coronary arteries, an x-ray, or angiogram, is obtained. (
  • Patients should always consult their family doctor first before considering whether a Coronary CT angiogram is right for them. (
  • Angiogram procedures are the "golden standard" for evaluating if someone has Coronary Heart Disease (CAD). (
  • In a coronary angiogram, which is generally done by a cardiologist, a catheter is placed into an artery in the groin or wrist. (
  • We used a JL4 catheter to cannulate the left main coronary artery. (
  • Multivariate analysis showed that predictors of hard and all events were obstructive CAD, three-vessel CAD, and left main coronary artery (LMCA) disease. (
  • Recommended indications include significant left main coronary artery stenosis, stenosis ≥70% in the proximal left anterior descending (LAD) and proximal left circum﫿ex artery, and 3-vessel coronary artery disease. (
  • Sakhuja R, Gandhi S. Diagnostic coronary angiography. (
  • Guidelines for percutaneous transluminal coronary angioplasty: a report of the American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures. (
  • In an effort to help clarify the potential diagnostic role of CTCA in "real-world" practice, investigators at four Canadian centers participated in a multivendor field evaluation of 64-slice CTCA and comparison with conventional coronary angiography. (
  • Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. (
  • den Dekker MA, de Smet K, de Bock GH, Tio RA, Oudkerk M, Vliegenthart R. Diagnostic performance of coronary CT angiography for stenosis detection according to calcium score: systematic review and meta-analysis. (
  • Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown. (
  • Coronary arteriography, also called coronary angiography , is the standard diagnostic test for coronary artery. (
  • Multidetector computed tomography coronary angiography (MDCT-CA) is a reliable imaging modality with high diagnostic performance for the detection of obstructive coronary lesions in patients with suspected CAD ( 3 ). (
  • Dual-source computed tomography (DSCT) allows to study coronary arteries with excellent diagnostic quality in all subjects independent of the heart rate, thus avoiding the use of beta-blockers. (
  • Background - Coronary angiograms are important in the diagnostic workup of patients with suspected coronary artery disease. (
  • The purpose of this study is to compare the difference of diagnostic efficiency between coronary CT angiography and myocardial perfusion single photon emission computerized tomography in asymptomatic patients with type 2 diabetes mellitus. (
  • Therefore in our study, we compare the difference of diagnostic efficiency between coronary CT angiography and myocardial perfusion single photon emission computerized tomography in asymptomatic patients with type 2 diabetes mellitus. (
  • The diagnostic evaluation of a non-ST elevation acute coronary syndrome and the general management of these patients are presented elsewhere. (
  • The RIPCORD (Does routine pressure wire assessment influence management strategy at coronary angiography for diagnosis of chest pain) study was designed to assess whether routine assessment of FFR in all the main coronary branches would significantly change the management strategy derived from diagnostic angiography alone. (
  • They all underwent diagnostic coronary angiography carried out by one cardiologist who used the results to develop a treatment plan (plan 1) giving recommendations for medical treatment, percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG) or to request more information. (
  • Routine use of FFR at diagnostic coronary angiography resulted in a significant change in management in 26% of patients," Curzen reported. (
  • He suggested that RIPCORD has provided proof of principle and that a large-scale randomised trial comparing angiographic- with FFR-guided assessment and management of patients with stable angina undergoing diagnostic angiography is now warranted. (
  • Diagnostic Accuracy of Myocardial Perfusion Imaging With CZT Technology: Systemic Review and Meta-Analysis of Comparison With Invasive Coronary Angiography. (
  • Diagnostic performance of coronary angiography by 64-row CT. (
  • Nonoperative dilatation of coronary-artery stenosis: percutaneous transluminal coronary angioplasty. (
  • The authors reported that 53% of the entire cohort had clinically significant disease, defined as ≥50% stenosis by conventional coronary angiography. (
  • The distal right coronary artery has a discrete calcified 70% stenosis. (
  • Stenosis severity and extent of coronary artery disease are important prognostic indicators. (
  • Provocation test (60 μ g of ergonovine in physiological saline into the left coronary artery over a period of 3 minutes) showed coronary spasm in the mid-LAD causing up to 70% stenosis by quantitative coronary analysis (Figure 1(b) ). (
  • a) Coronary angiography showed atherosclerotic change with mild stenosis in the left anterior descending artery. (
  • b) Ergonovine provocation induced coronary spasm in the mid-left anterior descending artery (arrows), causing up to 70% stenosis as demonstrated by quantitative coronary analysis. (
  • If a re-stenosis is suspected, the patient is imaged at the ESRF in orientations that allow visualisation of the right coronary artery, and within the next few days with the conventional technique at the hospital. (
  • The synchrotron method is a very efficient minimally-invasive technique to visualise and quantify coronary stenosis. (
  • The authors determined predictors of normal coronary angiograms (0% coronary stenosis) and compared rates of patients with normal catheterizations across centers. (
  • Researchers used 16-row CT to evaluate stenosis in 22 patients who then received conventional angiography. (
  • Successful delivery and deployment of the study scaffold/stent at the intended target lesion and successful withdrawal of the delivery system with attainment of final in-scaffold/stent residual stenosis of less than 30% by quantitative coronary angiography (QCA). (
  • Researchers had tried since the 1930s to develop a technique for viewing coronary arteries, which is considered necessary for diagnosing and treating coronary artery disease . (
  • Considered the "gold standard" for diagnosing coronary artery disease , angiography is now done so frequently that it is almost commonplace. (
  • You are going to have surgery on your heart and you are at high risk for coronary artery disease. (
  • 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. (
  • The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. (
  • Coronary angiography is also considered to be the best method of diagnosing coronary heart disease , where a build-up of fatty substances in the coronary arteries affects the heart's blood supply. (
  • In patients presenting with stable chest pain with low to intermediate predicted risk of coronary artery disease, CT coronary angiography leads to more accurate detection of coronary artery disease, fewer second-line investigations and more definitive rule out of coronary artery disease with lower cost to reach diagnosis compared with exercise tolerance testing. (
  • NICE guideline 95 proposes using CT coronary angiography (CTCA) in patients at low predicted risk of coronary artery disease only. (
  • We designed this audit to compare the performance of CT coronary angiography versus exercise tolerance testing (ETT) in patients presenting with stable chest pain and low AND intermediate predicted risk of coronary artery disease. (
  • To determine whether CT coronary angiography can outperform exercise tolerance testing in patients presenting with stable chest pain at higher predicted risk of coronary artery disease (i.e. not just low risk, as recommended by NICE clinical guideline 95, but also intermediate risk). (
  • The majority of patients presenting with stable chest pain ultimately have coronary artery disease excluded and CTCA is known to have excellent negative predictive value. (
  • We compared the performance of each test in terms of ability to exclude coronary artery disease, requirement for second-line investigations and total cost per patient to reach diagnosis. (
  • CT coronary angiography (CTCA) is a highly effective first-line investigation in those patients assessed to be at low-intermediate predicted risk of coronary artery disease. (
  • However, it is much less effective in patients with extensive coronary artery disease (due to coronary artery calcification degrading image quality) and alternative investigations such as functional testing or invasive coronary angiography are more appropriate. (
  • When this happens, it's called coronary artery disease (CAD). (
  • CT coronary angiography (CTCA) compared favorably with conventional angiography in predicting probable coronary disease -- but its accuracy varied widely across institutions, researchers found. (
  • Overall, CTCA had a sensitivity of 81.3% and a specificity of 93.3% in 169 patients who had low to intermediate pretest probability of coronary artery disease (CAD), according to a study reported online in Archives of Internal Medicine . (
  • In the other group, dyspnea (68.6%) and valvular heart disease (88.5%) constituted the most common indications for angiography. (
  • He has a history of hypertension and no known coronary artery disease (CAD). (
  • Contraindications to computed tomographic angiography (CTA) include renal disease, severe allergy to iodine contrast, inability to follow breath-hold instructions, and pregnancy. (
  • CAD indicates coronary artery disease. (
  • Noninvasive coronary artery imaging: magnetic resonance angiography and multidetector computed tomography angiography: a scientific statement from the american heart association committee on cardiovascular imaging and intervention of the council on cardiovascular radiology and intervention, and the councils on clinical cardiology and cardiovascular disease in the young. (
  • The procedure is performed to diagnose many heart conditions, including coronary artery disease (CAD), narrowing of the existing stent, and evaluation of coronary bypass graft patency. (
  • Coronary CT angiography , or coronary computed tomographic angiography, is an advanced non-invasive test for coronary artery disease (CAD). (
  • Coronary artery disease is the leading cause of death in the United States. (
  • The subject receives an intravenous injection of radiocontrast and then the heart is scanned using a high speed CT scanner, allowing physicians to assess the extent of occlusion in the coronary arteries, usually in order to diagnose coronary artery disease. (
  • This is because the test is highly sensitive (over 90% detection rate), so a negative test result largely rules out coronary artery disease (i.e. the test has a high negative predictive value). (
  • Therefore, the technique is able to identify characteristics of coronary artery disease that are associated to the development of acute coronary syndrome. (
  • This potential risk must be weighed against the competing risk of not diagnosing a significant health problem in a particular individual, such as coronary artery disease. (
  • These steps were repeated for each coronary vessel and under experimentally simulated coronary heart disease. (
  • Thermal imaging coronarography (TIC) allowed a clear representation of the morphology and course of the coronary vessels and of experimentally simulated coronary heart disease, moreover, demonstrated to be easy to perform during or after autopsies on ex situ hearts, non-destructive, reproducible, and cheap. (
  • On the basis of these preliminary results, TIC might allow a subsequent more focused and comprehensive cardiopathological examination of the heart, which remains mandatory for the definitive diagnosis of coronary heart disease. (
  • The primary end point was death from coronary heart disease or nonfatal myocardial infarction at 5 years. (
  • In this trial, the use of CTA in addition to standard care in patients with stable chest pain resulted in a significantly lower rate of death from coronary heart disease or nonfatal myocardial infarction at 5 years than standard care alone, without resulting in a significantly higher rate of coronary angiography or coronary revascularization. (
  • obvious sign of coronary artery disease and their. (
  • Of the 226, angiography showed that 28.3 percent had severe enough coronary artery disease to also require bypass surgery, in addition to valve surgery. (
  • Computerized tomography angiography and magnetic resonance angiography are rapidly positioning themselves as the emerging imaging technology for diagnosing coronary artery disease. (
  • OBJECTIVE To assess the prognostic role of multidetector computed tomography coronary angiography (MDCT-CA) in patients with diabetes with suspected coronary artery disease (CAD). (
  • RESEARCH DESIGN AND METHODS Between January 2006 and September 2007, 429 consecutive diabetic patients were prospectively studied with MDCT-CA for detecting the presence and assessing the extent of CAD (disease extension and coronary plaque scores). (
  • Diabetes is associated with premature atherosclerosis ( 1 ) and increased risk of coronary artery disease (CAD), which is the most common cause of death in patients with diabetes ( 1 ). (
  • They can quickly evaluate the heart and coronary arteries for plaque, a blockage or heart disease. (
  • In addition, atypical ischemic symptoms or no symptoms, the absence of diabetes, hyperlipidemia, smoking history, peripheral vascular disease, and angiography performed at a nonteaching site were associated with higher rates of normal catheterization. (
  • Of the lives lost to cardiovascular disease, coronary heart disease claims 53%, making it the leading cause of cardiovascular death. (
  • In fact, in 2002, nearly a half-million Americans died of coronary heart disease. (
  • Thought you might appreciate this item(s) I saw at Coronary Artery Disease. (
  • Coronary Angiography in Patients with Chronic Kidney Disease, Advances in the Diagnosis of Coronary Atherosclerosis Suna F. Kiraç, IntechOpen, DOI: 10.5772/21032. (
  • Coronary artery disease (CAD) is the leading cause of death in patients with diabetes. (
  • The goal of this study is to compare non-invasive computed tomography (CT) angiography with traditional coronary angiography to identify proximal, and hence revascularizable, coronary artery disease in patients with cardiomyopathy. (
  • Results of the CT angiography will be analyzed to determine sensitivity and specificity for identifying revascularizable coronary artery disease, compared to coronary angiography as the gold standard. (
  • Coronary angiography is standard in diagnosing coronary artery disease including: unstable angina, valvular heart disease, acute myocardial infarction, cardiomyopathy, or heart failure. (
  • Acute Coronary Syndromes (ACS) Blood Cardiovascular Dialysis Hypertension Stent Stroke Vascular Cardiovascular disease (CVD) includes all the diseases of the heart and circulation including coronary heart disease (angina. (
  • In some cases, the diagnosis of coronary heart disease (CHD) can be assumed with a high degree of probability after a careful study of the patient's complaints and his lifestyle. (
  • However, the "gold standard" study for diagnosing this disease is coronary angiography . (
  • 1,2 According to the American College of Cardiology/American Heart Association guidelines, CABG surgery is the standard of care in the treatment of advanced coronary artery disease. (
  • 4 The long-term clinical outcome after surgery is dependent on the patency of the bypass grafts and the progression of native coronary artery disease. (
  • Part I: Stress echocardiography in coronary heart disease. (
  • The technique is a well-recognized, safe and widely available stress test used for the diagnosis and assessment of prognosis in coronary heart disease, but may also prove valuable in valvular heart disease. (
  • How often should you empty your bowels every day, and when could you be at risk of coronary heart disease? (
  • According to the statistical data from the World Health Organization (WHO), coronary artery disease is one of the top causes of death. (
  • Nowadays, there are two main methods to diagnose coronary artery disease. (
  • It delivers a high accuracy of over 90% in detecting coronary artery disease. (
  • 3. Patients who have been treated for coronary artery disease by balloon angioplasty (PTCA) or percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG) , and need to see the result for further treatment. (
  • The purpose of this study is to compare clinical outcomes between QCA(quantitative coronary angiography)-guided and imaging-guided strategy in patients with native coronary artery disease undergoing Bioresorbable Vascular Scaffold implantation. (
  • Angiographic assessment of chest pain is flawed because it doesn't assess the functional significance of coronary artery disease," said the lead author of the study Nick Curzen, Professor of Interventional Cardiology, University Hospital Southampton NHS Foundation Trust and Faculty of Medicine, University of Southampton, Southampton, UK. (
  • He explained that ischaemia is the most important determinant of clinical outcome in coronary artery disease. (
  • The algorithm on the following page gives a scheme for the noninvasive evaluation of a patient with suspected coronary artery disease. (
  • Patients with angina and suspected coronary disease who, because of disability, illness or physical challenge, cannot be adequately risk-stratified by other means. (
  • An asymptomatic man or postmenopausal woman without known coronary heart disease with two or more major clinical risk factors and abnormal but not high-risk criteria on noninvasive testing (performed for indications stated in the ACC/AHA noninvasive testing guidelines). (
  • As a screening test for coronary artery disease in asymptomatic patients. (
  • OBJECTIVE Diabetic patients have a high prevalence of coronary artery disease (CAD), but timely diagnosis of CAD remains challenging. (
  • Diabetes is associated with a markedly increased risk for coronary artery disease (CAD), and CAD is the most common cause of death in diabetic adults ( 1 ). (
  • People who stand to benefit from Coronary CTAs are those who have no symptoms of heart disease or chest pain but who are in a "high-risk" category. (
  • Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? (
  • Background CT angiography (CTA) plays an important role in diagnosing coronary arterial disease. (
  • 12 Prognostic studies of patients early in the course of chronic coronary disease are lacking. (
  • Use of Coronary Computed Tomographic Angiography to Guide Management of Patients With Coronary Disease. (
  • It is considered the gold standard for diagnosing coronary artery disease, and is especially useful in higher-risk patients who are likely to need a procedure to open clogged coronary arteries. (
  • Coronary ischemia is linked to heart disease, and heart attacks. (
  • Coronary artery disease (CAD) is the most common cause of coronary ischemia. (
  • Coronary ischemia and coronary artery disease are contributors to the development of heart failure over time. (
  • Coronary artery disease (CAD) occurs when fatty substances, known as plaques, adhere to the walls of coronary arteries supplying the heart, narrowing them and constricting blood flow, a process known as atherosclerosis, the most common cause of coronary ischemia. (
  • Coronary ischemia resulting from coronary artery disease also increases the risk of developing heart failure. (
  • Most cases of heart failure result from underlying coronary artery disease. (
  • But the procedure is very expensive (one 1995 analysis priced angiography at $5,500 per procedure). (
  • Other studies reveal that physicians are not as likely to recommend angiography for their female patients, even when they exhibit the same symptoms as male patients who receive the procedure. (
  • Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the arteries in your heart. (
  • traditional procedure called coronary angiography . (
  • In 10 chapters the authors focus on subjects such as the technique of selective coronary angiography, anatomy of the normal and abnormal coronary artery tree, congenital anomalies of the coronary vessels, as well as indications, contraindications, complications, and side effects of the procedure. (
  • A coronary angiography is a fairly common procedure. (
  • Learn percutaneous coronary intervention advantages and disadvantage and view an animation of the procedure. (
  • Invasive, catheter-based coronary angiography is the clinical standard tool for assessment of the coronary arteries, but it has several shortcomings: First of all, it is an invasive procedure and, as such, is associated with a certain morbidity and mortality, which in most cases is a consequence of the required arterial access. (
  • Coronary balloon angioplasty is an interventional procedure wherein blood flow is restored in a blocked blood artery supplying the heart. (
  • This volume contains a literature review of coronary angiography, a comprehensive set of indications for performing this procedure, ratings of the appropriateness for each indication, and a medical record abstraction form and guidelines for its use. (
  • This 3D medical animation depicts a coronary angiography procedure. (
  • 6. Angioplasty and stenting of the right coronary artery. (
  • 4. RIGH CORONARY ARTERY: The right coronary artery is a large, dominant vessel. (
  • After informed consent, we cannulated the right coronary artery with a JR4 guider and crossed the lesion with a Cougar wire. (
  • Coronary arteries were cannulated, namely the anterior interventricular artery, the circumflex branch of the left coronary artery, and the right coronary artery. (
  • The excellent visualisation of the distal part of the right coronary artery (RCA) should be noted. (
  • Coronary arterial density was measured at the mid portion of the right coronary artery. (
  • Images revealed a 7cm segment total occlusion of the dominant right coronary artery, with distal reconstitution via collaterals. (
  • Double-oblique long-axis maximum intensity projection (MIP) image of the right coronary artery demonstrates a partially calcified plaque (white arrow) and a long segment, 7-centimeter occlusion of the RCA, with filling of the distal vessel via collaterals. (
  • Cumulative event-free survival was 100% for hard and all events in patients with normal coronary arteries, 78% for hard events and 56% for all events in patients with nonobstructive CAD, and 60% for hard events and 16% for all events in patients with obstructive CAD. (
  • 2 A noninvasive test that could identify patients with normal coronary arteries would be expected to reduce the number of invasive procedures. (
  • Coronary computed tomographic (CT) angiography (CTA) is a high-resolution, noninvasive technique to image the coronary arteries and to detect the presence, severity, and extent of CAD. (
  • Noninvasive CT angiography and stress tests can help predict which patients are likely to suffer a heart attack or other adverse cardiovascular event, according to a new study appearing online in the journal Radiology. (
  • In addition to being noninvasive, its tomographic nature allows for easier and unambiguous identification of the 3D anatomy of the coronary vessels, which can be useful in cases of coronary anomalies. (
  • CT angiography is considered noninvasive, since the only puncture comes from the small needle used for placing an intravenous line in the hand or arm. (
  • Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. (
  • Since the advent of coronary angioplasty more than 3 decades ago, the volume of percutaneous coronary interventions (PCI) has been rising progressively, with relative decrease in amount of coronary artery bypass graft (CABG) surgery. (
  • Proper treatment can be immediately performed by balloon angioplasty or percutaneous coronary intervention (PCI). (
  • IDR was any refractory ischemia-driven repeat percutaneous intervention or bypass graft surgery involving any native coronary or pre-existing bypass graft vessel. (
  • Fifteen randomly selected hospitals in New York State that provide coronary artery bypass graft surgery. (
  • Random sample of 1338 patients undergoing isolated coronary artery bypass graft surgery in New York State in 1990. (
  • The rates of inappropriate and uncertain use of coronary artery bypass graft surgery in New York State were very low. (
  • Cine coronary arteriography. (
  • Selective coronary arteriography. (
  • It usually involves taking X-rays of the heart's arteries (coronary arteries) using a technique called coronary angiography or arteriography. (
  • Compared to other non-invasive tests typically used to diagnose CAD, CTA has a number of advantages, including quicker diagnosis, increased patient comfort and convenience, and direct visualization of the coronary arteries. (
  • A new study presented at the EuroPCR 2013 reveals that measuring fractional flow reserve (FFR) with the help of pressure wire assessment during coronary angiography for diagnosis of chest pain can provide significant changes in the management of almost quarter of the patients. (
  • 23 May 2013, Paris, France: Routinely measuring fractional flow reserve (FFR) using pressure wire assessment during coronary angiography for diagnosis of chest pain leads to significant changes in the management of one in four patients, according to results from a study reported at EuroPCR 2013. (
  • Diagnosis of coronary ischemia is achieved by a attaining a medical history and physical examination in addition to other tests such as electrocardiography (EKG), stress testing, and coronary angiography. (
  • Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. (
  • Coronary CT Angiography and Subsequent Risk of Myocardial Infarction. (
  • This study shows that although acute myocardial infarction increases the risk of coronary angiography, it is justifiable if surgical therapy is contemplated. (
  • Most patients with a non-ST elevation acute coronary syndrome (unstable angina and non-ST elevation myocardial infarction) undergo coronary angiography and revascularization during the index hospitalization. (
  • See 'Initial evaluation and management of suspected acute coronary syndrome (myocardial infarction, unstable angina) in the emergency department' and 'Overview of the acute management of non-ST elevation acute coronary syndromes' . (
  • Unstable angina (UA) and non-ST elevation myocardial infarction (NSTEMI) are part of the continuum of acute coronary syndrome (ACS), which also includes ST-elevation myocardial infarction (STEMI). (
  • These changes have been associated with consistent reductions in long-term rates of fatal or non-fatal myocardial infarction.SummaryMajor beneficial effects in clinical management and patient outcomes are seen with the use of coronary computed tomography angiography. (
  • Exclusion criteria were 1 ) typical angina pectoris, 2 ) a history of myocardial infarction including electrocardiographic signs of a silent myocardial infarction, 3 ) a history of coronary revascularization, either by percutaneous coronary intervention or bypass or otherwise known CAD, 4 ) absence of stable sinus rhythm during the investigation, and 5 ) a life-threatening conditions. (
  • Visualization techniques in computed tomographic coronary angiography. (
  • Assessment by Coronary Computed Tomographic Angiography of. (
  • Angina in patients who are not candidates for coronary revascularization or in whom revascularization is not likely to improve the quality or duration of life. (
  • you'll probably have to undergo coronary angiography , in which. (
  • ROCHESTER, Minn. -- Mayo Clinic researchers discovered it is safe -- and much more convenient and less costly -- for many patients to undergo coronary angiography and elective valve surgery on the same day, it is reported in the current issue of Mayo Clinic Proceedings. (
  • When patients had positive result in either study, they will undergo coronary angiography for confirmation. (
  • We compared two cohorts of patients pre-and post introduction of CT coronary angiography (CTCA) in our hospital presenting with stable chest pain to the Rapid Access Chest Pain Clinic. (
  • Among symptomatic patients, chest pain (87.2%) and dyspnea (52.1%) were the only indications for coronary angiography. (
  • A 70-year-old woman, presenting with vague chest pain that she had been experiencing for the past year, was admitted for coronary angiography. (
  • Memisoglu and colleagues at Test Cardiovascular Imaging and the Siyami Ersek Heart Surgery Center in Istanbul enrolled 28 adult patients who previously had undergone conventional angiography: three for stable angina, three for atypical angina, six for chest pain, and two for shortness of breath. (
  • If a patient develops heart-related symptoms, such as chest pain, dizziness or light-headedness, a coronary angiography may be performed to test for the presence of plaque in the coronary arteries. (
  • When oxygen supply to the heart is unable to keep up with oxygen demand from the muscle, the result is the characteristic symptoms of coronary ischemia, the most common of which is chest pain. (
  • Chest pain due to coronary ischemia commonly radiates to the arm or neck. (
  • A key symptom of coronary ischemia is chest pain or pressure, known as angina pectoris. (
  • Interventional X-ray coronary angiography is a primary tool to guide catheter-based coronary interventions. (
  • Using X-ray images as a guide, the tip of the catheter is passed up to the heart and coronary arteries. (
  • Electron-beam CT angiography topped catheter angiography in determining the most at-risk adult patients with congenital coronary artery defects. (
  • For the most part, information obtained from catheter angiography is sufficient to diagnose coronary abnormalities. (
  • For catheter angiography, it's 2.5 mSv, provided the exam is done quickly and in good hands. (
  • Cardiologists sent the patients to be imaged by EBCT angiography (C-150 XP, GE Healthcare), where radiologists were blinded to the catheter angiographic results. (
  • It poses some risk for complications, e.g. dissection, because the catheter has to be inserted into an artery from a patient's groin or arm or wrist to be carefully threaded to coronary arteries. (
  • Following the angiography, the catheter and guide wire are removed. (
  • Commenting on the implications of the study findings, Kari Niemela, Medical Director and founder of the Heart Center Co., Tampere University Hospital, Tampere, Finland, said, "The RIPCORD trial demonstrated that routine measurement of FFR in patients with stable angina pectoris changes treatment plan in one out of four patients as compared to visual evaluation with coronary angiography alone. (
  • Objectives To determine whether coronary angiography for suspected stable angina pectoris is underused in older patients, women, south Asian patients, and those from socioeconomically deprived areas, and, if it is, whether this is associated with higher coronary event rates. (
  • The update provides additional pointers for medical practitioners who are considering computed tomography coronary angiography for their patients. (
  • The general prerequisites for patients undergoing computed tomography coronary angiography (CTCA) in order to achieve optimum image quality are set out in Box 1 . (
  • Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. (
  • Thermal imaging recognizes simulated occlusion/sub-occlusion of coronary arteries. (
  • Coronary angiography is performed to detect obstruction in the coronary arteries of the heart. (
  • Coronary angiography creates a digital image of the arteries of the heart, which is received after filling them with a radioopaque substance. (
  • In any event, the American College of Cardiology (ACC) and the American Heart Association (AHA) have joined to create specifications on how angiography should be used. (
  • A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Coronary Angiography). (
  • The American College of Cardiology (ACC) and the American Heart Association (AHA) have updated their guidelines for coronary angiography. (
  • CT angiography has made huge strides in recent years and, in some cardiology practices, is taking the place of nuclear stress testing for the initial evaluation of low- or intermediate-risk patients. (
  • The program addresses the fundamental concerns associated with conventional angiography, which requires the injection of a contrast agent directely into the coronary arteries by the mean of arterial cathetherization. (
  • 1998) are promising, but despite an active research in these domains, the conventional coronary angiography remains the gold standard technique. (
  • Point out that in this study across four centers attempting a real-world evaluation, CTCA appeared to have good accuracy when compared with conventional angiography. (
  • The popularity of CTCA as a less invasive alternative to conventional angiography has grown rapidly in recent years. (
  • Each patient underwent conventional angiography and CTCA, performed no more than 10 days apart. (
  • As compared with conventional angiography, CTCA had a PPV of 91.6% and NPV of 84.7%, in addition to the 81.3% sensitivity and 93.3% specificity. (
  • The programme addresses the fundamental concerns associated with conventional angiography, which requires the injection of a contrast agent directly into the coronary arteries by means of arterial catheterisation. (
  • Dutch researchers suggest it may be able to replace conventional angiography in some patients by dictating appropriate treatment without additional invasive imaging. (
  • 5-7 Conventional coronary angiography is traditionally used to assess the status of bypass grafts, but technical advances in multidetector computed tomography (MDCT) have given the radiologist the ability to evaluate bypass grafts noninvasively. (
  • What is the difference between conventional and CT coronary angiography? (
  • In addition to reviewing the previous guidelines, the 12-member ACC/AHA Committee on Coronary Angiography also conducted a search of the pertinent literature for the previous 10 years. (
  • In about five seconds, CTA provides your doctor with very clear and detailed pictures of your coronary arteries and heart, allowing for highly accurate detection of early CAD and narrowing of the arteries. (
  • This has lead to the development of several algorithms for automatic detection and grading of coronary stenoses. (
  • A recent meta-analysis showed high accuracies for the detection of coronary artery stenoses (CAS) by 64slice CT 2 (Table 1). (
  • FFR provides an accurate and reproducible method for detection of ischaemia by measuring the pressure drop across a lesion and previous studies have shown better clinical outcomes of FFR-guided treatment compared to angiography alone. (
  • Coronary angiography is an X-ray of the heart and blood vessels of a living patient. (
  • Coronary angiography can detect weakened blood vessel walls and narrowed or blocked vessels. (
  • Coronary CT angiography imaging uses computed tomography (CT) to look at the blood vessels (coronary arteries) that provide blood to the heart muscle. (
  • Coronary CT angiography uses a special computer to take multiple pictures of the heart and blood vessels using X-rays, and constructs a 3D picture of the arteries which can show the whether any material such as plaque has built up to cause a blockage. (
  • Thermal imaging allows the clear imaging of swine coronary vessels. (
  • The angiographies were taken during the examination of the vessels with an uncalibrated camera. (
  • Three-dimensional rotational coronary angiography (3DRCA) is a new technique for imaging coronary vessels in the human body. (
  • An angiography is an examination via X-Ray to study one's blood or lymph vessels. (
  • CT angiography provides your physicians with more-precise images of your blood vessels than either MRI or ultrasound technology. (
  • Not receiving appropriate angiography was associated with a higher risk of coronary events in all groups. (
  • The appropriateness of coronary angiography and coronary artery bypass surgery in the Trent regional health authority was assessed by comparison with predetermined consensus criteria. (
  • Finally, most previous studies have not taken account of the appropriateness of coronary angiography 15 or the confounding of comorbidity in decisions about investigations. (
  • Previously, with single-, 4-, and 8-row scanners, coronary CTA demonstrated variable degrees of success in detecting critical stenoses, and, as a result, was not considered robust enough for everyday clinical use. (
  • They found that coronary CTA had a sensitivity of 95% for detecting critical stenoses and a negative predictive value of 86% among the evaluable coronary artery segments. (
  • Imaging of the coronary arteries requires high temporal and spatial resolution. (
  • CT coronary angiography (CTCA) outperformed exercise tolerance testing (ETT) for each of the comparative measures described above (see supporting document for full results). (
  • Univariate analysis of potential predictors of false CTCA results (positive or negative) yielded pretest probability of CAD (OR 1.02, P =0.005) and presence of coronary calcification (OR 1.09, P =0.03). (
  • Designed for programs in transvenous coronary angiography, cerebral computed tomography (Dilmanian et al. (
  • One of the primary programs is the development of dual-energy transvenous coronary angiography for in vivo human research protocols. (
  • Although CTA avoids the inherent risks of stress testing in patients with suspected acute coronary syndrome (ACS), there are several strengths and limitations to consider ( Table 1). (
  • Safety end points were undetected acute coronary syndromes. (
  • There were no undetected acute coronary syndromes and no significant differences in major adverse cardiovascular events at 28 days. (
  • Left ventriculography with selective coronary angiography was performed on 13 patients with acute myocardial infarcts complicated by cardiogenic shock of left ventricular failure and hypotension. (
  • For smooth and safe conduct of coronary interventions, mastery of all steps of image acquisition and interpretation is mandatory. (
  • 1 Most 2 3 4 but not all 5 6 studies suggest that older people, 7 women, 8 ethnic minorities, 9 and those who are socioeconomically deprived 10 have less access to effective interventions for stable angina or acute coronary events. (
  • The history, technic, and complications of coronary angiography have been discussed. (
  • Addressing clinical needs of the aortic root and coronary arteries through the use of computational fluid dynamics and computed tomography. (
  • Forty-nine percent of coronary angiographies were considered to be entirely appropriate in relation to the patient's clinical condition, but 21 percent were deemed inappropriate. (
  • The CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) Registry, a large international multicenter study, strengthened the prognostic value of MDCT-CA still further and showed that patient risk for all-cause mortality differs with age and sex ( 8 ). (
  • Given rapid advances in technology, coronary CT angiography (CTA) may soon become a routine part of clinical practice. (
  • However, these studies do not yet provide enough information to determine the role of coronary CTA in clinical practice. (
  • For potential clinical applications, the advantages and diasdvantages of CTA must be weighed against those of invasive coronary angiography. (
  • In a consensus document, a group of experts from various professional societies have listed "appropriate" clinical indications for coronary CTA, based mostly on the considerations outlined above (Table 2). (
  • In the following section, potential clinical indications for the use of coronary CTA are outlined as a "Top Ten" list, from the clearest to the least robust and frequent indications. (
  • However if the clinical picture suggests a low probability of significant problem then it is reasonable to have CT angiography. (
  • Multidetector computed tomography (MDCT) has been demonstrated to be a very useful technique to non-invasively study coronary arteries. (
  • Landmarks in the development of coronary artery bypass surgery. (
  • Coronary artery bypass surgery was considered appropriate in 55 percent of patients, but inappropriate in 16 percent. (
  • Despite of the power of detecting myocardial ischemia functionally, there are limitations of SPECT in diagnosing subclinical coronary atherosclerosis anatomically. (
  • In recent advance in technology, coronary CT angiography (CTA) could detect subclinical coronary atherosclerosis. (
  • Angina can also occur due to spasm of the coronary arteries, even in individuals without atherosclerosis. (