Corneal Wavefront Aberration: Asymmetries in the topography and refractive index of the corneal surface that affect visual acuity.Corneal Topography: The measurement of curvature and shape of the anterior surface of the cornea using techniques such as keratometry, keratoscopy, photokeratoscopy, profile photography, computer-assisted image processing and videokeratography. This measurement is often applied in the fitting of contact lenses and in diagnosing corneal diseases or corneal changes including keratoconus, which occur after keratotomy and keratoplasty.Aberrometry: The use of an aberrometer to measure eye tissue imperfections or abnormalities based on the way light passes through the eye which affects the ability of the eye to focus properly.Refraction, Ocular: Refraction of LIGHT effected by the media of the EYE.Refractive Errors: Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.Accommodation, Ocular: The dioptric adjustment of the EYE (to attain maximal sharpness of retinal imagery for an object of regard) referring to the ability, to the mechanism, or to the process. Ocular accommodation is the effecting of refractive changes by changes in the shape of the CRYSTALLINE LENS. Loosely, it refers to ocular adjustments for VISION, OCULAR at various distances. (Cline et al., Dictionary of Visual Science, 4th ed)Pupil: The aperture in the iris through which light passes.Astigmatism: Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed)Lenses: Pieces of glass or other transparent materials used for magnification or increased visual acuity.Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.Keratomileusis, Laser In Situ: A surgical procedure to correct MYOPIA by CORNEAL STROMA subtraction. It involves the use of a microkeratome to make a lamellar dissection of the CORNEA creating a flap with intact CORNEAL EPITHELIUM. After the flap is lifted, the underlying midstroma is reshaped with an EXCIMER LASER and the flap is returned to its original position.Retinoscopes: Instruments for RETINOSCOPY that determines the refractive state of the EYE, such as the degree of NEARSIGHTEDNESS; FARSIGHTEDNESS; or ASTIGMATISM. In principle, a retinoscope provides a light source to illuminate the RETINA, and then locates the aerial image of the retina in space to obtain an index of the refractive quality of the patient's lens system.Cornea: The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)Diagnostic Techniques, Ophthalmological: Methods and procedures for the diagnosis of diseases of the eye or of vision disorders.Lasers, Excimer: Gas lasers with excited dimers (i.e., excimers) as the active medium. The most commonly used are rare gas monohalides (e.g., argon fluoride, xenon chloride). Their principal emission wavelengths are in the ultraviolet range and depend on the monohalide used (e.g., 193 nm for ArF, 308 nm for Xe Cl). These lasers are operated in pulsed and Q-switched modes and used in photoablative decomposition involving actual removal of tissue. (UMDNS, 2005)Chromosome Aberrations: Abnormal number or structure of chromosomes. Chromosome aberrations may result in CHROMOSOME DISORDERS.Visual Acuity: Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.Optics and Photonics: A specialized field of physics and engineering involved in studying the behavior and properties of light and the technology of analyzing, generating, transmitting, and manipulating ELECTROMAGNETIC RADIATION in the visible, infrared, and ultraviolet range.Keratoplasty, Penetrating: Partial or total replacement of all layers of a central portion of the cornea.Keratoconus: A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)Equipment Design: Methods of creating machines and devices.Lasers: An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.Hyperopia: A refractive error in which rays of light entering the eye parallel to the optic axis are brought to a focus behind the retina, as a result of the eyeball being too short from front to back. It is also called farsightedness because the near point is more distant than it is in emmetropia with an equal amplitude of accommodation. (Dorland, 27th ed)Eye: The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.Optometry: The professional practice of primary eye and vision care that includes the measurement of visual refractive power and the correction of visual defects with lenses or glasses.Presbyopia: The normal decreasing elasticity of the crystalline lens that leads to loss of accommodation.Cathode Ray Tube: A vacuum tube equipped with an electron emitting CATHODE and a fluorescent screen which emits visible light when excited by the cathode ray. Cathode ray tubes are used as imaging devises for TELEVISIONS; COMPUTER TERMINALS; TEXT TELECOMMUNICATION DEVICES; oscilloscopes; and other DATA DISPLAY devices.Privacy: The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)Confidentiality: The privacy of information and its protection against unauthorized disclosure.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Informed Consent: Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.Genetic Privacy: The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Corneal Surgery, Laser: Surgical techniques on the CORNEA employing LASERS, especially for reshaping the CORNEA to correct REFRACTIVE ERRORS.Epithelium, Corneal: Stratified squamous epithelium that covers the outer surface of the CORNEA. It is smooth and contains many free nerve endings.Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Postural Balance: A POSTURE in which an ideal body mass distribution is achieved. Postural balance provides the body carriage stability and conditions for normal functions in stationary position or in movement, such as sitting, standing, or walking.Posture: The position or attitude of the body.Cataract Extraction: The removal of a cataractous CRYSTALLINE LENS from the eye.Burning Mouth Syndrome: A group of painful oral symptoms associated with a burning or similar sensation. There is usually a significant organic component with a degree of functional overlay; it is not limited to the psychophysiologic group of disorders.Ophthalmic Solutions: Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.Lens Implantation, Intraocular: Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.Phacoemulsification: A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)Carboxypeptidases A: Carboxypeptidases that are primarily found the DIGESTIVE SYSTEM that catalyze the release of C-terminal amino acids. Carboxypeptidases A have little or no activity for hydrolysis of C-terminal ASPARTIC ACID; GLUTAMIC ACID; ARGININE; LYSINE; or PROLINE. This enzyme requires ZINC as a cofactor and was formerly listed as EC 3.4.2.1 and EC 3.4.12.2.Arecaceae: The palm family of order Arecales, subclass Arecidae, class Liliopsida.Combretum: A plant genus of the family COMBRETACEAE. Triterpenes and combretastatin have been identified in members of this genus.Eichhornia: A plant genus of the family PONTEDERIACEAE that is used as a biological filter for treating wastewater.Paullinia: A plant genus of the family SAPINDACEAE. The seed of P. cupana is the source of guarana powder which contains 4% CAFFEINE.Maytenus: A plant genus of the family CELASTRACEAE.MART-1 Antigen: A melanosome-specific protein that plays a role in the expression, stability, trafficking, and processing of GP100 MELANOMA ANTIGEN, which is critical to the formation of Stage II MELANOSOMES. The protein is used as an antigen marker for MELANOMA cells.

Ocular wavefront aberrations in patients with macular diseases. (1/53)

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Aberration control and vision training as an effective means of improving accommodation in individuals with myopia. (2/53)

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Study of ocular aberrations with age. (3/53)

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The effect of the asphericity of myopic laser ablation profiles on the induction of wavefront aberrations. (4/53)

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Measurement of the time course of optical quality and visual deterioration during tear break-up. (5/53)

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Detection of subclinical keratoconus by using corneal anterior and posterior surface aberrations and thickness spatial profiles. (6/53)

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Corneal aberrations and visual acuity after laser in situ keratomileusis: femtosecond laser versus mechanical microkeratome. (7/53)

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Estimation of the depth of focus from wavefront measurements. (8/53)

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  • There are also many related questions that need to be answered regarding the natural stimulus for focusing, the patients' perception of the aberrations and their correction, and vision simulation with computational technologies that allow us to anticipate and interpret the outcomes for the patient. (lww.com)
  • The results were fascinating in that primary topography-guided procedures provided better outcomes for these primary eyes than routine wavefront-optimised procedures for visual quality including night driving. (springer.com)
  • At my practice, we have achieved superb outcomes in these patients using ORange intraoperative wavefront aberrometer (WaveTec Vision, Aliso Viejo, CA). If this technology is not available, I recommend printing a topographic map and drawing a line through the middle of the skewed axes to use as a landmark. (crstoday.com)
  • We have designed and built a binocular Hartmann-Shack wave-front sensor using a single microlens array and camera for real-time aberration measurement of both eyes in an open-view configuration. (um.es)
  • There, he encountered several corneal transplant patients who had vision issues after their operation that could not be explained using conventional measurement systems. (rochester.edu)
  • The majority of ophthalmologists who perform refractive surgery use this preoperative measurement, often as part of their planning for wavefront-optimized or wavefront-guided surgical treatments. (medscape.com)
  • 19,20 Recent technologies, such as the Amaris Total- Tech laser (Schwind eye-tech-solutions, Kleinostheim, Germany), can facilitate measurement of and potentially compensate for static cyclotorsion that occurs when the patient moves from the upright to the supine position during the procedure 21 by quantifying the cyclorotation occurring between wavefront measurement and laser refractive surgery 22 and compensating for it. (crstodayeurope.com)
  • 8 ‐ 10 ] It follows that the analysis of the total wavefront aberrations of the eye would provide the most direct and complete measurement of retinal image quality and therefore can be directly related to visual performance. (pubmedcentralcanada.ca)
  • Following the introduction, chapters are divided into the following sections: � Wavefront Measurement and Correction � Retinal Imaging Applications � Vision Correction Applications � Design Examples Readers will discover the remarkable proliferation of new applications of wavefront-related technologies developed for the human eye. (whsmith.co.uk)
  • Each technique focuses on creating an epithelial flap under which an excimer laser is used to sculpt the corneal tissue. (medscape.com)
  • Elevation data were imported into VolPro (Sarver & Assoc.) to calculate the AW and SW aberrations for a 6mm analysis zone. (escrs.org)
  • Despite the large inter-subject variability, the population average of the root mean square for all aberrations (excluding defocus) remained constant for accommodative levels up to 3.0 D. Even though aberrations change with accommodation, the magnitude of the aberration change remains less than the magnitude of the uncorrected aberrations, even at high accommodative levels. (arvojournals.org)
  • There are three principal factors that limit the finest details an eye can see: optical (due to scattering, diffraction, chromatic and monochromatic aberration), retinal and neural factors (limiting visual acui (mais) ty to an approximate maximum of 20/10 or 2.0). (worldwidescience.org)
  • Pubmed ID: 14691158 To investigate the effects of alcohol and mitomycin C (MMC) on cultured corneal fibroblast of the rabbit to determine the safety of this compound for clinical use. (jove.com)
  • The next article will deal with the peculiarities of the wavefront analysis, as well as with some of the clinical and surgical applications to the day-to-day ophthalmic practice. (worldwidescience.org)