Corneal perforation. Medical search

A puncture or hole through the CORNEAL STROMA resulting from various diseases or trauma.

Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.

Deeply perforating or puncturing type intraocular injuries.

Opening or penetration through the wall of the INTESTINES.

Infections in the inner or external eye caused by microorganisms belonging to several families of bacteria. Some of the more common genera found are Haemophilus, Neisseria, Staphylococcus, Streptococcus, and Chlamydia.

Diseases of the cornea.

Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.

Inflammation of the cornea.

Partial or total replacement of all layers of a central portion of the cornea.

Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.

The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)

An opening or hole in the ESOPHAGUS that is caused by TRAUMA, injury, or pathological process.

Infection, moderate to severe, caused by bacteria, fungi, or viruses, which occurs either on the external surface of the eye or intraocularly with probable inflammation, visual impairment, or blindness.

Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)

Infections with bacteria of the genus SERRATIA.

Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.

Infections with bacteria of the genus PSEUDOMONAS.

A temporary or persistent opening in the eardrum (TYMPANIC MEMBRANE). Clinical signs depend on the size, location, and associated pathological condition.

A hole or break through the wall of the UTERUS, usually made by the placement of an instrument or INTRAUTERINE DEVICES.

Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.

Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.

The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.

A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.

A condition with trapped gas or air in the PERITONEAL CAVITY, usually secondary to perforation of the internal organs such as the LUNG and the GASTROINTESTINAL TRACT, or to recent surgery. Pneumoperitoneum may be purposely introduced to aid radiological examination.

Bursting of the STOMACH.

Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)

A group of compounds having the general formula CH2=C(CN)-COOR; it polymerizes on contact with moisture; used as tissue adhesive; higher homologs have hemostatic and antibacterial properties.

A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental.

An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.

A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.

Partial or total replacement of the CORNEA from one human or animal to another.

Purulent infections of the conjunctiva by several species of gram-negative, gram-positive, or acid-fast organisms. Some of the more commonly found genera causing conjunctival infections are Haemophilus, Streptococcus, Neisseria, and Chlamydia.

A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA.

Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.

Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)

The turning inward (inversion) of the edge of the eyelid, with the tarsal cartilage turned inward toward the eyeball. (Dorland, 27th ed)

Inflammation of the retinal vasculature with various causes including infectious disease; LUPUS ERYTHEMATOSUS, SYSTEMIC; MULTIPLE SCLEROSIS; BEHCET SYNDROME; and CHORIORETINITIS.

Inflammation of the lacrimal sac. (Dorland, 27th ed)

A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.

Green dyes containing ammonium and aryl sulfonate moieties that facilitate the visualization of tissues, if given intravenously. They have mostly been used in the study of kidney physiology.

Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.

A plant family of the order Eucommiales, subclass Hamamelidae, class Magnoliopsida (some botanists have classified this in the order Hamamelidales or Urticales). Eucomia is an elmlike tree of central and eastern China. Leaves are alternate; deciduous flowers are solitary and unisexual and lack petals and sepals. The male flowers have 6 to 10 stamens and female flowers have one ovary of two carpels, one of which aborts during development so the fruit (a dry, winged structure) contains only one seed. The latex is a source of RUBBER. Tochu tea is an aqueous extract of Eucommia ulmoides leaves and a popular beverage in Japan. (Mutat Res 1997 Jan 15;388(1):7-20).

Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

A plant genus of the family AQUIFOLIACEAE. The common name of 'holly' usually refers to this genus but may sometimes refer to similar looking plants of the MAHONIA or QUERCUS genus.

Enhancing effects of sericin on corneal wound healing in Otsuka Long-Evans Tokushima fatty rats as a model of human type 2 diabetes. (1/15)

The protein sericin is the main constituent of silk. We investigated the effects of sericin on corneal wound healing in Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model for human type 2 diabetes. Corneal wounds were prepared by removal of the corneal epithelium, and documented using a TRC-50X equipped with a digital camera. Sericin solutions were instilled into the eyes of rats five times a day following corneal abrasion. Plasma glucose and triglycerides were determined using an Accutrend GCT. Cholesterol and insulin were measured using a Cholesterol E-Test Kit and ELISA Insulin Kit, respectively. The plasma levels of glucose, triglycerides, cholesterol and insulin in 38-week-old OLETF rats were significantly higher than in Long-Evans Tokushima Otsuka (LETO) rats used as normal controls, and the rate of corneal wound healing in OLETF rats was slower than in LETO rats. The corneal wounds of rats instilled with saline showed almost complete healing by 72 h after corneal epithelial abrasion. On the other hand, the corneal healing rate of OLETF rats instilled with 10% sericin solution was significantly higher than that of LETO rats instilled with saline, and the wounds showed almost complete healing at 48 h after abrasion. The corneal healing rate increased with increasing sericin concentration. The present study demonstrates that the corneal wound healing rate in OLETF rat is slower than in LETO rats, and the instillation of sericin solution has a potent effect in promoting wound healing and wound-size reduction in LETO and OLETF rats. (+info)

Corneal perforation with preseptal cellulitis in a patient with acute lymphocytic leukemia. (2/15)

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One cornea for two patients: case report. (3/15)

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Four cases of corneal perforation in patients with chronic graft-versus-host disease. (4/15)

PURPOSE: To report the clinical features and investigate the underlying pathological processes of spontaneous corneal perforation in patients with ocular chronic graft-versus-host disease (cGVHD). METHODS: A full ophthalmological evaluation of corneal perforation in four patients with cGVHD was performed. Three of them underwent deep anterior lamellar keratoplasty and samples from two of three patients were used for histopathological analyses. RESULTS: Three patients were successfully treated by corneal transplantation. One patient was treated with a therapeutic soft contact lens, and the wound healed within 2 days. The common clinical features of these patients were (1) the presence of definite dry eye related to cGVHD in 3 of 4 patients and probable dry eye in one patient, (2) a central or paracentral site of corneal ulceration and perforation, with no sign of infection, and (3) prior use of a topical or systemic corticosteroid, and/or topical non-steroidal anti-inflammatory drugs. Immunohistochemical findings revealed an increased number of cluster of differentiation 68(+) (CD68(+)) macrophages and matrix metalloproteinase 9 (MMP-9) expression in the tissue surrounding the perforation. CONCLUSIONS: Our report extends current information on the clinical features and pathological processes of corneal perforation in cGVHD by showing increased MMP-9 expression and the accumulation of CD68(+) positive macrophages in the affected areas. (+info)

Tectonic deep anterior lamellar keratoplasty in impending corneal perforation using cryopreserved cornea. (5/15)

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VIP and growth factors in the infected cornea. (6/15)

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Synthetic fiber from a teddy bear causing keratitis and conjunctival granuloma: case report. (7/15)

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Superimposed fungal ulcer after fibrin glue sealant in infectious corneal ulcer. (8/15)

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serious or fatal gastrointestinal tract perforations. *skin toxicity *bullous, blistering, and exfoliative skin conditions ( ... corneal lesions. *Pulmonary toxicity *interstitial pneumonitis. *bronchiolitis obliterans with organizing pneumonia (BOOP) ...

https://en.wikipedia.org/wiki/Erlotinib

Neurotrophic: corneal nerve damage causes persistent epithelial defect, thinning and even perforation. Cornea becomes ... Uncommon Necrotising interstitial keratitis: Characterised by stromal infiltrates, corneal thinning and possibly perforation. ... "Herpetic Corneal Infections: Herpes Zoster Ophthalmicus". www.aao.org. Retrieved 21 December 2019. Khurana AK (2008). ... Disciform Keratitis (Disciform Endotheliitis): a disc of corneal oedema, folds in Descemet's membrane, mild inflammation ...

https://en.wikipedia.org/wiki/Herpes_zoster_ophthalmicus

More severe exposures can result in keratitis, iritis, corneal perforation, and blindness. Respiratory: Irritation of the ...

https://en.wikipedia.org/wiki/Phosgene_oxime

The eye infection can lead to corneal scarring or perforation, ultimately resulting in blindness. If the newborn is exposed ...

https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae

In cases of corneal ulceration or perforation, or if corneal scarring is severe, corneal transplant may be required. This ... Corneal ulceration, or in severe cases, perforation, can also occur and may be accompanied by hypopyon. In cases of keratitis, ... Soft contact lenses are more adherent to the corneal surface than hard lenses, which allows the Acanthamoeba organism to bind ... AK should be considered in all patients who use contact lenses, and following corneal abrasions or trauma. A thorough history ...

https://en.wikipedia.org/wiki/Acanthamoeba_keratitis

PMD lacks apical corneal scarring, Rizutti's phenomenon, Munson's sign, and the central corneal thickness is usually normal. ... Rarely, it may cause acute vision loss with severe pain due to perforation of the cornea. It is typically characterized by a ... Intacs implants, corneal collagen cross-linking, and corneal transplant surgery are additional options. Surgery is reserved for ... The gold standard diagnostic test for PMD is corneal topography. However, it may not be as specific as corneal pachymetry, ...

https://en.wikipedia.org/wiki/Pellucid_marginal_degeneration

Besides, reduced tearing with erosion and neovascularization of the cornea leads to corneal opacification and perforation. ...

https://en.wikipedia.org/wiki/Pemphigoid

It is used as a screening test for many corneal disorders including corneal post-trauma, corneal perforation and corneal ... If the fluorescein strip turns pale upon application to the corneal surface, the person tests positive for the corneal ... Any changes in color or surface of the fluorescence area indicate the presence of corneal leakage. ...

https://en.wikipedia.org/wiki/Seidel_test

If corneal ulcer is detected, it may be treated medically with antibiotics. If corneal perforation has occurred, immediate ... It can lead to corneal ulceration and permanent loss of vision due to corneal opacity. Normally, corneal surface is kept moist ... This will lead to corneal epithelial damage. Both tear film and corneal epithelium play significant role in corneal protective ... Fluorescein staining may be used to detect for epithelial defects, corneal infection or perforation of the cornea. Tear break- ...

https://en.wikipedia.org/wiki/Exposure_keratopathy

Surgery may be indicated if scleral perforation or excessive scleral thinning is present. Bandage contact lens or corneal glue ... may be used to repair damaged corneal tissue in the eye and preserve the patient's vision. If not treated, scleritis can cause ...

https://en.wikipedia.org/wiki/Scleritis

Corneal perforation can occur in patients with untreated or partially treated infectious keratitis and requires surgical ... It is a dry looking corneal ulcer with satellite lesions in the surrounding cornea. Usually associated with fungal ulcer is ... from the corneal scraping. Recent advances have been made in PCR ref 3./immunologic tests which can give a much quicker result ... intervention in the form of corneal transplantation. This disease is quite common in the tropics and with large agrarian ...

https://en.wikipedia.org/wiki/Fungal_keratitis

Serious side effects such as corneal perforation were not reported in studies but only during post-marketing in less than one ...

https://en.wikipedia.org/wiki/Bromfenac

Lin is then restrained by the neck with an animal control pole, threatened by Renhao with corneal perforation from a wall dart ...

https://en.wikipedia.org/wiki/Mon_Mon_Mon_Monsters

Application of the Seidel Test in Zone I will rule out seepage of the anterior chamber through a corneal perforation, while ... thereby determining the presence of corneal perforation and pathological anterior chamber leakage. Zone II: region designated ... Globe perforation, oculoplastic intervention, and neuro-ophthalmic injuries contribute significantly to reported poor visual ... the conjunctiva and corneal surface; the most common injuries seen in this zone are foreign debris retention by the conjunctiva ...

https://en.wikipedia.org/wiki/Blast-related_ocular_trauma

... spontaneous corneal epithelium breakdown, poor corneal healing and development of corneal ulceration, melting and perforation. ... In the most severe forms (stage III), it is necessary to stop the progression towards corneal perforation: in these cases, a ... Corneal contact lenses can also be used in this stage of the disease, for their protective action to improve corneal healing. ... Corneal sensitivity test: performed by placing a cotton wad or cotton thread in contact with the corneal surface: this only ...

https://en.wikipedia.org/wiki/Neurotrophic_keratitis

... after corneal perforation. Therapeutic: To remove inflamed corneal tissue unresponsive to treatment by antibiotics or anti- ... Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced ... In corneal disorders where vision correction is not possible by using contact lenses, intrastromal corneal ring segments may be ... Corneal collagen cross-linking may delay or eliminate the need for corneal transplantation in keratoconus and post-LASIK ...

https://en.wikipedia.org/wiki/Corneal_transplantation

By using the corneal pachymetry the surgeon will reduce the chances of perforation of the eye and improves surgical outcome. ... Corneal pachymetry is essential for other corneal surgeries such as Limbal Relaxing Incisions. LRI is used to reduce corneal ... think of it as a corneal A-scan. Pachymetry using the corneal waveform allows the user to more accurately measure the corneal ... Pachymetry using the corneal waveform process allows the user to more accurately measure the corneal thickness, verify the ...

https://en.wikipedia.org/wiki/Corneal_pachymetry

This is because contact lens wearers are often colonized with Pseudomonas aeruginosa, which may cause corneal perforations and ... Corneal abrasions are also a common and recurrent feature in people who suffer specific types of corneal dystrophy, such as ... Fowler GC (2011), "Corneal Abrasions and Removal of Corneal or Conjunctival Foreign Bodies", Pfenninger and Fowler's Procedures ... Ahmed F, House RJ, Feldman BH (September 2015). "Corneal Abrasions and Corneal Foreign Bodies". Primary Care. 42 (3): 363-75. ...

https://en.wikipedia.org/wiki/Corneal_abrasion

This type of ulcer is especially dangerous and can rapidly result in corneal perforation, if not treated in time. The location ... Deep ulcers extend into or through the stroma and can result in severe scarring and corneal perforation. Descemetoceles occur ... In ophthalmology, a corneal ulcer usually refers to having an infectious cause while the term corneal abrasion refers more to ... Fungal corneal ulcers require intensive application of topical anti-fungal agents. Viral corneal ulceration caused by herpes ...

https://en.wikipedia.org/wiki/Corneal_ulcer

It results when healing occurs after perforation of cornea with incarceration of iris. The iris is adherent to the back of a ... Corneal transplantation Corneal ulcer Corneal button "WHO -Priority eye diseases". www.who.int. J Alroy , M Haskins, D E Birk ( ... The word 'Corneal blindness' is commonly used to describe blindness due to corneal opacity. Depending on the density, corneal ... Femtosecond laser-assisted corneal tattooing: Femtosecond laser-assisted corneal tattooing is a new corneal tattooing technique ...

https://en.wikipedia.org/wiki/Corneal_opacity

Corneal perforation Eardrum perforation Esophageal perforation Gastrointestinal perforation Nasal septum perforation Stercoral ... A perforation is a small hole in a thin material or web. Perforation may also refer to: A leaf feature Perforation (oil well), ... perforation Uterine perforation This disambiguation page lists articles associated with the title Perforation. If an internal ... a term used in philately Postage stamp perforation, used to separate postage stamps Film perforations, the holes placed in the ...

https://en.wikipedia.org/wiki/Perforation_(disambiguation)

... is an anomaly in the cornea resulting from damage to the corneal surface. A corneal perforation means that ... Non infected corneal perforation generally heals when a pressure bandage is used. For certain types of corneal perforations, ... Damage to the cornea due to corneal perforation can cause decreased visual acuity. Corneal perforation may cause difficulty in ... Pellucid marginal degeneration may cause corneal thinning, leading to perforation. Corneal perforation can be diagnosed by ...

https://en.wikipedia.org/wiki/Corneal_perforation

Deep ulcers extend into or through the stroma and can result in severe scarring and corneal perforation. Descemetoceles occur ... Other eye conditions can cause corneal ulcers, such as entropion, distichiae, corneal dystrophy, and keratoconjunctivitis sicca ... or corneal transplant. Topical corticosteroids and anesthetics should not be used on any type of corneal ulcer because they ... as disruption of the corneal epithelium allows attachment and colonisation of the underlying tissues by normal corneal ...

https://en.wikipedia.org/wiki/Corneal_ulcers_in_animals

This type of ulcer is especially dangerous and can rapidly result in corneal perforation, if not treated in time. ... Refractory corneal ulcersEdit. Main article: Recurrent corneal erosion. Refractory corneal ulcers are superficial ulcers that ... Superficial and deep corneal ulcersEdit. Corneal ulcers are a common human eye disease. They are caused by trauma, particularly ... Seasonal corneal ulcerEdit. *Christmas Eye, a seasonal epidemic of corneal ulceration which predominantly occurs only within a ...

https://en.m.wikipedia.org/wiki/Corneal_ulcer

This is because contact lens wearers are often colonized with Pseudomonas aeruginosa, which may cause corneal perforations and ... Corneal abrasions are also a common and recurrent feature in people who suffer specific types of corneal dystrophy, such as ... Fowler, Grant C. (2011), "Corneal Abrasions and Removal of Corneal or Conjunctival Foreign Bodies", Pfenninger and Fowler's ... Ahmed, Faheem; House, Robert James; Feldman, Brad Hal (1 September 2015). "Corneal Abrasions and Corneal Foreign Bodies". ...

https://en.m.wikipedia.org/wiki/Corneal_abrasion

... for corneal ectasias involving corneal periphery". Br J Ophthalmol. 92 (2): 286-90. doi:10.1136/bjo.2007.124628. PMID 18227208 ... The patient is at risk for globe perforation because the thinned out cornea is extremely weak. It is a much rarer condition ... It causes corneal thinning, primarily at the margins, resulting in a spherical, slightly enlarged eye. It is sometimes equated ... Further progression of the disease usually leads to a need for corneal transplantation because of extreme thinning of the ...

https://en.wikipedia.org/wiki/Keratoglobus

In a model of cecum perforation-induced sepsis, ALOX5 gene knockout mice exhibited a decrease in the number of neutrophils and ... and corneal injury. These studies indicate that Alox5 can serve a protective function presumably by generating metabolites such ...

https://en.m.wikipedia.org/wiki/5-Lipoxygenase

Topical antibiotics without steroids for chronically discharging ears with underlying eardrum perforations PMID 16235370 https ... Toric intraocular lens versus limbal relaxing incisions for corneal astigmatism after phacoemulsification PMID 31845757 https ... Done Oral antivirals for preventing recurrent herpes simplex keratitis in people with corneal grafts PMID 27902849 https://doi. ... Done Immunosuppressants for the prophylaxis of corneal graft rejection after penetrating keratoplasty PMID 26313245 https://doi ...

https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Medicine/Cochrane/Cochrane_Review_List/Musculoskeletal,_Oral,_Skin_and_Sensory

Nasal septum perforation. Nasal septal hematoma. tonsil. Tonsillitis. Adenoid hypertrophy. Peritonsillar abscess. ... or perforation of thoracic organs (i.e. chylothorax, esophageal rupture). ...

https://en.wikipedia.org/wiki/Pleural_disease

... after corneal perforation.. *Therapeutic: To remove inflamed corneal tissue unresponsive to treatment by antibiotics or anti- ... Corneal collagen cross-linking[edit]. Corneal collagen cross-linking may delay or eliminate the need for corneal ... Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced ... Intrastromal corneal ring segments[edit]. In corneal disorders where vision correction is not possible by using contact lenses ...

https://en.wikipedia.org/wiki/Keratoplasty

... where a mandible dated to approximately 2650 BC shows two perforations just below the root of the first molar, indicating the ... Corneal transplantation. *Photorefractive keratectomy. *Intrastromal corneal ring segment. *Corneal collagen cross-linking ...

https://en.wikipedia.org/wiki/Resection_

Ahmed, Faheem; House, Robert James; Feldman, Brad Hal (1 September 2015). "Corneal Abrasions and Corneal Foreign Bodies". ... perforation, intestinal fistulas, volvulus, and obstruction.[3] ...

https://en.wikipedia.org/wiki/Airway_foreign_body

Lenses were hexagonally close packed, touching each other, with a single corneal membrane covering all lenses. Each lens was in ... ridging and perforations. The exact purpose of the prosopon is not resolved but suggestions include structural strengthening, ...

https://en.wikipedia.org/wiki/Trilobite

Others may result in perforation of the cornea, endophthalmitis (an infection inside the eye), or even loss of the eye. With ... Facts About the Cornea and Corneal Disease The National Eye Institute (NEI) Filimentary keratitis. ... Acanthamoebic keratitis Amoebic infection of the cornea is a serious corneal infection, often affecting contact lens wearers. ... A Pseudomonas Protease Capable of Mediating Corneal Erosions". Invest Ophthalmol Vis Sci. 50 (8): 3794-801. doi:10.1167/iovs.08 ...

https://en.wikipedia.org/wiki/Keratitis

The perforations were found with the growth of fine bone spurs, which indicate that trepanation had been carried out on live ... In modern eye surgery, a trephine instrument is used in corneal transplant surgery. The procedure of drilling a hole through a ... The intentional perforation of the cranium exposes the dura mater to treat health problems related to intracranial diseases or ...

https://en.wikipedia.org/wiki/Trepanning

... cornea 371.0 Corneal scars and opacities 371.1 Corneal pigmentations and deposits 371.2 Corneal oedema 371.3 Changes of corneal ... Acute myringitis without mention of otitis media 384.1 Chronic myringitis without mention of otitis media 384.2 Perforation of ... membranes 371.4 Corneal degenerations 371.5 Hereditary corneal dystrophies 371.6 Keratoconus 371.7 Other corneal deformities ... Interstitial and deep keratitis 370.6 Corneal neovascularization 370.8 Other forms of keratitis 370.9 Unspecified 371 Corneal ...

https://en.wikipedia.org/wiki/List_of_ICD-9_codes_320–389:_diseases_of_the_nervous_system_and_sense_organs

Contact with the eyes may result in irritation, corneal burns, and eye damage. Persons with pre-existing skin, eye, or central ... At the molecular level, amatoxins cause damage to cells of these organs by causing perforations in the plasma membranes ...

https://en.wikipedia.org/wiki/Amatoxin

This is significant for example if the patient requires anaesthesia for a trauma and has sustained an eye (globe) perforation. ... Grieshaber MC, Schoetzau A, Zawinka C, Flammer J, Orgul S (June 2007). "Effect of central corneal thickness on dynamic contour ... A newer transpalpebral and transscleral tonometry method is not influenced by corneal biomechanics and does not need to be ... Measured values of intraocular pressure are influenced by corneal thickness and rigidity. As a result, some forms of refractive ...

https://en.wikipedia.org/wiki/Intraocular_pressure

The inner third joins with some choroidal tissue to form a plate (lamina cribrosa) across the optic nerve with perforations ... as opposed to the near-uniform thickness and parallel arrangement of the corneal collagen. Moreover, the cornea bears more ...

https://en.wikipedia.org/wiki/Sclera

Corneal perforation is an anomaly in the cornea resulting from damage to the corneal surface. A corneal perforation means that ... Corneal perforation can be diagnosed by using the Seidel test. Any aqueous leakage is revealed during the Seidel test confirms ... If the clear aqueous humor from the eye runs through the yellow stain, the patient tests positive for corneal perforation. ... The treatment of corneal perforation depends on the location, severity and the cause of damage ...

https://en.wikipedia.org/wiki/Corneal_perforation

... of an autologous fibrin membrane and platelet-rich plasma clot appears to be safe and effective for treating perforated corneal ... Corneal perforations can be caused by trauma or ulcerative disease and "constitute a major ophthalmic emergency necessitating ... The clot was then placed over the corneal perforation underneath the fibrin membrane, after which the membrane was attached to ... The procedure "is a safe and effective surgical alternative for the closure of corneal perforations," they wrote. "This ...

https://www.medpagetoday.com/ophthalmology/generalophthalmology/38285

... at the site of corneal perforation. After 36 hours of occlusion, a layer of fibrin covered the perforation, closing the defect ... Sterile non-traumatic corneal perforation treated with Tachosil®].. [R Cañones-Zafra, J Benítez-Herreros, K Kubiak, M A Montes- ... Successful healing of the corneal perforation was observed in the follow-up, with no recurrences of the process. Tachosil(®) is ... The slit-lamp examination showed a central corneal perforation of 1mm in diameter, with no associated infection or inflammatory ...

https://www.sigmaaldrich.com/catalog/papers/21821194

... and complications in the group of patients with corneal perforation. Materials and Methods. 247 eyes with corneal perforation ... the surgical treatment of corneal perforations show that there is no one-size-fits-all surgical approach to corneal perforation ... In peripheral corneal perforations and descemetoceles and when the perforation is relatively small (i.e., it does not require ... and in corneal perforations. The advantage of this method is lower risk of corneal rejection [17, 18]. ...

https://www.hindawi.com/journals/joph/2017/1582532/

... Katarzyna Krysik,1 Dariusz Dobrowolski,1,2 ... "Differences in Surgical Management of Corneal Perforations, Measured over Six Years," Journal of Ophthalmology, vol. 2017, ...

https://www.hindawi.com/journals/joph/2017/1582532/cta/

Fibrin glue provides faster healing and induces significantly less corneal vascularization, but it requires a significantly ... Fibrin glue and cyanoacrylate tissue adhesive are both effective in the closure of corneal perforations up to 3 mm in diameter ... Fibrin glue versus N-butyl-2-cyanoacrylate in corneal perforations Ophthalmology. 2003 Feb;110(2):291-8. doi: 10.1016/S0161- ... Participants: Forty-one patients (41 eyes) with corneal perforations up to 3 mm in diameter with a positive Seidels test were ...

https://pubmed.ncbi.nlm.nih.gov/12578769/?dopt=Abstract

PubMed journal article Penetrating keratoplasty with small-diameter and glycerin-cryopreserved grafts for eccentric corneal ... perforation were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad. ... AdolescentAdultAstigmatismChildCorneaCorneal DiseasesCorneal InjuriesCorneal UlcerCryopreservationCryoprotective AgentsEye ... Penetrating keratoplasty for corneal perforations in fungal keratitis.. *Shortterm and longterm visual and astigmatic results ...

https://www.unboundmedicine.com/medline/citation/19512909/Penetrating_keratoplasty_with_small_diameter_and_glycerin_cryopreserved_grafts_for_eccentric_corneal_perforations_

The usefulness of Pentacam in the diagnosis and management of Descemets membrane perforation during deep anterior lamellar ... Corneal Imaging with Pentacam After Descemets Membrane Perforation During Deep Anterior Lamellar Keratoplasty. Ma Teresa ... Corneal Imaging with Pentacam After Descemets Membrane Perforation During Deep Anterior Lamellar Keratoplasty. ... A) Severe Corneal Edema and Double Anterior Chamber Seen in Slit Lamp Examination. (B) Scheimpflug Images (pentacam): ...

https://www.healio.com/ophthalmology/journals/osli/2011-11-42-6/%7B35599ce0-7290-440d-9f23-b18979b7c4d6%7D/corneal-imaging-with-pentacam-after-descemets-membrane-perforation-during-deep-anterior-lamellar-keratoplasty

Corneal scrapings were performed where relevant.. Results: The characteristics associated with corneal perforation in microbial ... Conclusions: This study characterises microbial keratitis cases at increased risk of corneal perforation and reinforces the ... Aim: To identify predisposing factors leading to corneal perforation in patients with microbial keratitis. ... Method: Two groups of 60 patients each, with perforated corneal ulcers and healed/healing corneal ulcers, respectively, were ...

https://bjo.bmj.com/content/90/6/686

Impaired functionality of desmosomes of the corneal epithelium caused the recurrent corneal ulcerations with perforation. ... A corneal perforation at the peripheral 6 oclock position was closed by an incarceration of the iris. The anterior chamber was ... Descemetocele without corneal perforation or intraocular inflammation. (B) Right eye, May 2001: conjunctival injection, ... We describe the first case of recurrent severe bilateral corneal ulcerations with perforation in a female patient with ...

https://bjo.bmj.com/content/86/10/1192

Corneal perforation requiring corneal grafting: a rare complication of gonococcal eye infection ... Corneal perforation requiring corneal grafting: a rare complication of gonococcal eye infection ... The authors present a case of severe gonococcal conjunctivitis associated with corneal perforation of the right eye in a 25- ... Inpatient management and corneal grafting were required. The authors demonstrate that Neisseria gonorrhoea should be considered ...

https://sti.bmj.com/content/86/6/447

Methods: A retrospective review of all corneal perforations from 2009 through 2014 was performed. Corneal perforations managed ... Surgical Management of Corneal Perforations: Primary Patch Graft versus Penetrating Keratoplasty Jeanie Y Paik; Emily Waisbren ... Surgical Management of Corneal Perforations: Primary Patch Graft versus Penetrating Keratoplasty You will receive an email ... Purpose: The purpose of our study is to review cases of corneal perforations and to compare surgical outcomes of primary ...

http://iovs.arvojournals.org/article.aspx?articleid=2331265

Eyes with corneal perforations generally have significant underlying pathology, such as corneal ulcers, trauma, serious ... Does my Surgery Class 1 rating cover me for sealing corneal perforations with tissue adhesive?. Although the act of gluing a ... For these reasons, coverage for sealing corneal perforations with tissue adhesive is not included within the Surgery Class 1 ... corneal perforation is not technically difficult, the risks associated with this activity warrant Surgery Class 2 rating. ...

https://www.omic.com/policyholder/does-my-surgery-class-1-rating-cover-me-for-sealing-corneal-perforations-with-tissue-adhesive/

This rapidly progressed to severe infectious keratitis and corneal perforation in both eyes, despite intensive antibiotics to ... Nosocomial Klebsiella pneumoniae conjunctivitis resulting in infectious keratitis and bilateral corneal perforation. ... pneumoniae conjunctivitis complicated by infectious keratitis and corneal perforation in both eyes. Methods. An 83-year-old ... Nosocomial Klebsiella pneumoniae conjunctivitis resulting in infectious keratitis and bilateral corneal perforation. Cornea 17 ...

http://scholarbank.nus.edu.sg/handle/10635/131074

"Corneal Perforation" by people in this website by year, and whether "Corneal Perforation" was a major or minor topic of these ... "Corneal Perforation" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Corneal Perforation" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Corneal Perforation". ...

https://profiles.uchicago.edu/profiles/display/28882

Corneal Perforation. Can be caused by:. *Progressive corneal thinning due to ectatic degeneration, Terriens degeneration, ...

https://www.columbiaeye.org/education/digital-reference-of-ophthalmology/cornea-external-diseases/surgery-complications/corneal-perforation

... Abstract. Reliable closure of the cornea wounds after trauma or ... using the corneal injury model in rabbits); evaluated the capacity of the corneal cells to integrate into produced gel to ... This originates from the crucial role of the corneal structure and curvature in the eyes overall function, as the improper ... Reliable closure of the cornea wounds after trauma or disease as well as incisions for cataract, LASIK, corneal transplant, and ...

https://programme.exordo.com/nanop2016/delegates/presentation/168/

Corneal Ulcer Impending Perforation Disease Astaxanthin Lyme Symptoms are coughing a runny nose sore throat and The eye feels ... Night blindness caused Corneal Ulcer Impending Perforation Disease Astaxanthin Lyme by Vitamin A Deficiency is due to ... Corneal Ulcer Impending Perforation Disease Astaxanthin Lyme. Taken as a whole these pictures convey more ... Corneal Ulcer Impending Perforation Disease Astaxanthin Lyme unexplained repetitive serious injuries such as dental injuries ( ...

http://www.bass2014.eu/eyes-bass2014/corneal-ulcer-impending-perforation-disease-astaxanthin-lyme/

Given the severity of the clinic, a penetrating keratoplasty is conducted two days after admission and the corneal button was ... peripheral infiltration and nasal perforation in the right eye after a not affiliated case of urethritis is reported. Methods: ... A 40-year-old male with a severe corneal melting, ... The diagnosis of corneal perforation was then confirmed as a ... Corneal Perforation in a Patient with History of Unidentified Urethritis. Author(s) Glenda Espinosa-Barberi1*, Sara Miranda ...

https://m.scirp.org/papers/82311

Vargas-Villanueva, A., Carvajal-Saiz, N., Muñoz-Ortiz, J. et al. Bilateral corneal perforation and iris prolapse as a ... Bilateral corneal perforation and iris prolapse as a complication non-peripheral ulcerative keratitis in a patient with ... Intraocular pressure (IOP) was not measured due to the presence of corneal perforation and indirect ophthalmoscopy evaluation ... Bilateral corneal ulcers, in OD inferior-paracentral located (white arrow) with iris exposure and in OS centrally located ( ...

https://joii-journal.springeropen.com/articles/10.1186/s12348-020-0195-6

... as manifested by the development of bilateral corneal ulceration with corneal perforation in the right eye. The oral ... as manifested by the development of bilateral corneal ulceration with corneal perforation in the right eye. The oral ... as manifested by the development of bilateral corneal ulceration with corneal perforation in the right eye. The oral ... as manifested by the development of bilateral corneal ulceration with corneal perforation in the right eye. The oral ...

https://kyushu-u.pure.elsevier.com/en/publications/spontaneous-healing-of-corneal-perforation-after-temporary-discon

Spontaneous corneal perforation in a patient with unusual unilateral pellucid marginal degeneration ... examination demonstrated peripheral corneal edema extending between the 2 and 6 oclock positions as well as a perforation ... This case represents an unusual, unilateral corneal ectatic disorder, most likely pellucid marginal degeneration. (C) 2001 ...

https://avesis.acibadem.edu.tr/yayin/f9e5dd8e-406c-45ca-bb4e-e2c07b5c767d/spontaneous-corneal-perforation-in-a-patient-with-unusual-unilateral-pellucid-marginal-degeneration

Corneal perforation during laser in situ keratomileusis. Joo, Choun-Ki; Kim, Tae-Gyung ... Corneal shape changes after temporal and superolateral 3.0 mm clear corneal incisions. Rainer, Georg; Menapace, Rupert; Vass, ... Corneal flap thickness in laser in situ keratomileusis using an SCMD manual microkeratome. Yi, Won-Mo; Joo, Choun-Ki ... Corneal topography classification in myopic eyes based on axial, instantaneous, refractive, and profile difference maps. Budak ...

https://journals.lww.com/jcrs/toc/1999/08000

Terrien Marginal Degeneration Presenting With Spontaneous Corneal Perforation. Srinivasan, Sathish; Murphy, Conor C; Fisher, ... Effects of Corneal Neovascularization on the Manifestations of Avellino Corneal Dystrophy (Granular Corneal Dystrophy Type II) ... Corneal Staining After Treatment With Topical Tetracycline. Lapid-Gortzak, Ruth; Nieuwendaal, Carla P; Slomovic, Allan R; More ... Analysis of Corneal Surface Evolution After Moderate Alkaline Burns by Using Impression Cytology. López-García, J S; Rivas, L; ...

https://journals.lww.com/corneajrnl/toc/2006/09000

To show the utility of intracameral fibrin glue in corneal perforation. Setting: La Mancha-Centro Hospital, Alcázar de San Juan ... The use of these adhesives in the anterior chamber is an useful and easily solution for treating small corneal perforation. ... We present four cases with corneal perforation. In all of them we introduced the fibrin tissue adhesive (Tissucol®, Baxter Labs ... Intracameral fibrin glue in corneal perforation. Poster Details. First Author: M. Pradas González SPAIN ...

http://www.escrs.org/Copenhagen2016/programme/posters-details.asp?id=25873

Corneal perforation from phlyctenular keratoconjunctivitis is rarely reported worldwide and no case has been reported in Korea ... We report a case of corneal perforation in a patient with phlyctenular keratoconjunctivitis along with a literature review. ... Slit-lamp examination revealed a corneal perforation at the center of the thinned cornea. Hence, we performed an emergent ... Adolescent , Erlotinib Hydrochloride , Blepharitis , Cornea , Corneal Perforation , Diagnosis , Female , Humans , Keratitis , ...

https://search.bvsalud.org/gim/resource/en/wpr-90220

Corneal Perforation. 8. 8. Hypersensitivity/Allergic reaction. 7. 7. Corneal Infiltrates. 7. 7. ...

https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfTPLC/tplc.cfm?id=5818

Full text: Available Index: IMSEAR (South-East Asia) Main subject: Humans / Corneal Diseases Language: English Journal: Indian ... Full text: Available Index: IMSEAR (South-East Asia) Main subject: Humans / Corneal Diseases Language: English Journal: Indian ... Management of corneal thinning and perforation. Management of corneal thinning and perforation. ...

https://search.bvsalud.org/gim/resource/en/sea-72588

Nontraumatic corneal perforation. Cornea. 2000;19:313-9.CrossRefPubMedGoogle Scholar ... Open globe Corneal patch graft Corneal glue Corneal necrosis Intracameral antibiotics This is a preview of subscription content ... Cyanoacrylate glue for corneal perforations: a description of a surgical technique and a review of the literature. Clin Exp ... Management of nontraumatic corneal perforation with tectonic drape patch and cyanoacrylate glue. Cornea. 2010;29:1173-5. ...

https://link.springer.com/chapter/10.1007%2F978-3-319-72410-2_33

His corneal epithelial disorders initially improved, but subsequently worsened, as manifested by the development of bilateral corneal ulceration with corneal perforation in the right eye. (elsevier.com)
To describe bilateral corneal perforation secondary to severe peripheral corneal ulceration in a male patient without ocular infection or systemic rheumatological diseases. (escrs.org)
A 27-year-old male patient presented with bilateral peripheral corneal ulceration following a 10-month history of ocular discomfort and redness. (escrs.org)
Animal studies suggest that these acute injuries can be followed by recurrent or delayed symptoms, including ulceration, inflammation, and corneal erosion. (nap.edu)
Corneal ulceration leading to perforation is associated with infectious and non-infectious destructive conditions in the cornea. (biomedcentral.com)
u-PA and u-PAR co-localization was seen in the corneal ulceration area. (biomedcentral.com)
Discontinue TARCEVA for corneal perforation, ulceration or persistent severe keratitis. (nih.gov)
Fracture of the orbit may result in damage to the nerve that provides vision and cornea, resulting in corneal ulceration or blindness. (acvs.org)
Most foreign bodies affect the cornea either by mechanical irritation, resulting in a painful corneal ulceration, or by puncturing the cornea. (acvs.org)
Dryness severity, corneal ulceration and scarring, cataract and glaucoma were also associated with a greater likelihood of severe visual impairment (SVI), Dr. Sayan Basu and colleagues from the LV Prasad Eye Institute in Hyderabad, India, report in the American Journal of Ophthalmology. (medscape.com)
Corneal ulceration and melting are the most frequent vision-threatening complications of SS, occurring in up to 4% of patients, the authors note. (medscape.com)
At presentation, 29 patients had corneal ulceration and 17 had perforation. (medscape.com)
Anti-collagenase medications have been successfully used to treat corneal ulceration (keratocele). (news-medical.net)
Peripheral corneal ulceration is another manifestation of rheumatoid arthritis that may result in ocular perforation. (aao.org)
Patients with rheumatoid arthritis who develop peripheral corneal ulceration or scleritis have an associated risk for developing potentially lethal systemic vasculitis. (aao.org)
GI bleeding, ulceration or perforation. (mims.com)
Ulcerative keratitis (corneal ulceration) occurs very commonly in dogs. (akcchf.org)
While corneal ulcers occur in all breeds of dogs, brachycephalic breeds such as Pekingese, Lhasa Apsos and Shih Tzus, have a higher incidence of ulceration. (akcchf.org)
It usually is caused by chronic corneal ulceration, trauma, or corneal exposure. (petmd.com)
Called corneal ulceration, the condition will become progressively more severe as the cell loss outpaces the generation of new epithelial cells. (cornell.edu)

Corneal perforation is an anomaly in the cornea resulting from damage to the corneal surface. (wikipedia.org)
A corneal perforation means that the cornea has been penetrated, thus leaving the cornea damaged. (wikipedia.org)
Damage to the cornea due to corneal perforation can cause decreased visual acuity. (wikipedia.org)
Perforation of the cornea may occur due to diseases of the cornea, injury during eye surgery, or infection of the eye, which may occur after surgery or procedures. (wikipedia.org)
Reliable closure of the cornea wounds after trauma or disease as well as incisions for cataract, LASIK, corneal transplant, and other ophthalmic surgeries needs special care and immediate treatment, yet remains one of the key. (exordo.com)
The treatment was restarted and the symptoms improved but the corneal lesion continuously progressed towards the center, thinning the central cornea . (bvsalud.org)
Slit-lamp examination revealed a corneal perforation at the center of the thinned cornea . (bvsalud.org)
However, occasionally phlyctenular keratoconjunctivitis may not respond to treatment and may spread to the central cornea causing loss of visual acuity and even corneal perforation in rare occasions. (bvsalud.org)
The corneal epithelium is derived from a specific group of stem cells, encircling the cornea, that multiply and ultimately form mature corneal cells. (nap.edu)
Corneal nutrition is supplied almost exclusively by the aqueous humor circulating behind the cornea in the front of the eye. (nap.edu)
In these processes, inflammatory cells such as macrophages and activated corneal fibroblasts persist in the cornea, causing an imbalance between tissue degradation and remodeling, and eventually worsening the pathological condition. (biomedcentral.com)
In the current investigation, we observed expressions of u-PA, u-PAR, CD68, α-smooth muscle actin (α-SMA) and α2AP using the cornea of a patient with a corneal perforation. (biomedcentral.com)
The center of the cornea was perforated ( A ) and corneal stromal opacity with fibrosis was seen surrounding the perforation area ( B ). (biomedcentral.com)
The most feared complication of this condition is thinning of the cornea, secondary descemetocele, and eventual perforation of the cornea that may result in endophthalmitis and loss of the eye. (medscape.com)
There was no increase in cornea perforations in our patient population," Acharya said. (ucsf.edu)
A full thickness hole in the cornea may be the result of traumatic injury to the eye or progression of a melting corneal ulcer. (acvs.org)
A foreign body containing iron that embeds in the cornea can create a defect in corneal epithelium known as a rust ring. (aafp.org)
Perforation of the globe is a full-thickness laceration of the cornea or sclera caused by trauma, often a penetrating foreign body. (aafp.org)
Our preliminary research showed that in corneal alkali injury rabbits, the UC-MSCs can accelerated the cornea repair, inhibited angiogenesis. (clinicaltrials.gov)
This usually happens as a result of a disruption to the cornea, such as in the presence of a corneal ulcer or perforation. (news-medical.net)
Other surgical methods include a partial or full corneal transplant, if the cornea is severely damaged, with little chance of natural or medicated recovery. (news-medical.net)
CONCLUSION: The oil red O positive deposits and their variation in density in the subepithelial area of the cornea may have caused the characteristic whorl-like corneal opacity in this woman who was heterozygous for Fabry's disease. (biomedsearch.com)
In this study, we demonstrate that after corneal P. aeruginosa infection, both Th1 and Th17 cells infiltrate the cornea with increased representation of Th17 cells. (jimmunol.org)
In addition to Th1 and Th17 cells, regulatory T cells also migrate into the cornea during early as well as late stages of corneal pathology. (jimmunol.org)
The inflammatory response in the cornea is mainly initiated and maintained by sequential migration and activation of proinflammatory cells from both innate and adaptive immune response against invading corneal P. aeruginosa infection ( 4 ). (jimmunol.org)
Corneal sequestrum occurs when the cat has dead corneal tissue (or dark spots in the cornea). (petmd.com)

This study characterises microbial keratitis cases at increased risk of corneal perforation and reinforces the need for standardised referral and treatment protocols for patients with corneal ulcer on their first contact at primary care level in the developing world. (bmj.com)
Corneal Ulcer Impending Perforation Disease Astaxanthin Lyme unexplained repetitive serious injuries such as dental injuries (like oken teeth) Black eyes in both eyes at the same time swelling or tenderness in the. (bass2014.eu)
Night blindness caused Corneal Ulcer Impending Perforation Disease Astaxanthin Lyme by Vitamin A Deficiency is due to Malnutrition. (bass2014.eu)
The patient underwent extensive medical and laboratory testing to rule out an infectious or systemic cause of his corneal ulcer. (escrs.org)
To determine the localization of urokinase-type plasminogen activator (u-PA), u-PA receptor (u-PAR) and α2-antiplasmin (α2AP) in the tissue of a corneal perforation, we investigated immunohistochemical expressions of u-PA, u-PAR, α2AP, CD68, and α-smooth muscle actin (α-SMA) in a patient with corneal perforation that developed from an ulcer of no clear cause. (biomedcentral.com)
The patient was a 77-year-old woman who presented with a perforated corneal ulcer in her right eye. (biomedcentral.com)
The cause of her corneal ulcer was unknown. (biomedcentral.com)
We identified expression of the u-PA/u-PAR complex and α2AP in a patient with a corneal ulcer. (biomedcentral.com)
The detailed time line of corneal ulcer development was unknown. (biomedcentral.com)
Superficial changes such as corneal erosion or deeper structural defects such as a corneal ulcer can often be discerned with the naked eye. (aerzteblatt.de)
Lesions in dogs were four perforations, three descemetoceles, two limbal melanocytomas and one deep corneal ulcer. (unboundmedicine.com)
Active or history of peptic ulcer/haemorrhage, history of GI bleeding or perforation related to previous NSAID therapy, blood formation disorder of unclear etiology, nasal polyps (associated w/ angioneurotic oedema), severe heart failure. (mims.com)
Postoperative corneal ulcer management with a broad-spectrum topical antibiotic, atropine ointment, and a tear supplement. (petmd.com)
Personally I have not seen a corneal ulcer in any patient, from all walks of life, when they are diligent about not sleeping in their contacts overnight (and of course they also practice other good hygiene habits with contacts). (iwindsurf.com)
Since self-trauma may aggravate a corneal ulcer and interfere with the healing process, an affected cat may be required to wear an Elizabethan collar until the ulcer is completely healed. (cornell.edu)
If we think that the corneal ulcer is probably caused by the herpesvirus," says Dr. Kern, "we'll prescribe a drug called cidofovir, which is given twice daily to prevent viral cells from replicating. (cornell.edu)

For certain types of corneal perforations, lamellar keratoplasty is used as treatment. (wikipedia.org)
The three surgical procedures, dependent on size and location of perforation, were performed: full-sized penetrating keratoplasty, corneoscleral patch graft, and anterior lamellar keratoplasty. (hindawi.com)
This procedure includes full-thickness penetrating keratoplasty, anterior lamellar keratoplasty (ALK), and corneal patch grafts. (hindawi.com)
Penetrating keratoplasty (PK) is limited to large perforations with extensive necrosis [ 2 - 5 , 13 , 14 ]. (hindawi.com)
To report the outcome of penetrating keratoplasty with small-diameter and glycerin-cryopreserved grafts for eccentric corneal perforation. (unboundmedicine.com)
Small-diameter penetrating keratoplasty seems to be effective in treating various eccentric corneal perforations. (unboundmedicine.com)
The usefulness of Pentacam in the diagnosis and management of Descemet's membrane perforation during deep anterior lamellar keratoplasty (DALK) was described and reported. (healio.com)
Deep anterior lamellar keratoplasty (DALK) is a partial thickness corneal graft, which replaces the affected stroma and retains the corneal endothelium. (healio.com)
The purpose of our study is to review cases of corneal perforations and to compare surgical outcomes of primary penetrating keratoplasty (PK) versus repair with a small diameter lamellar or full-thickness patch graft. (arvojournals.org)
Given the severity of the clinic, a penetrating keratoplasty is conducted two days after admission and the corneal button was sent to microbiology, which polymerase chain reaction was positive for Neisseria gonorrhoeae . (scirp.org)
The oral administration of erlotinib was interrupted in preparation for tectonic keratoplasty, but 2 days later the corneal perforation of the right eye and the bilateral epithelial defects had healed spontaneously. (elsevier.com)
The use of cyanoacrylate tissue adhesive offers to the clinician a safe technique for healing corneal wounds that avoids tectonic penetrating keratoplasty with its associated complications. (springer.com)
Hydrops after corneal perforation during manual deep anterior lamellar keratoplasty for keratoconus. (nih.gov)
Since lamellar keratoplasty has developed for replacing only a diseased corneal layer, new advantages and challenges showed up [ 1 , 2 , 3 , 4 ]. (intechopen.com)
The anterior layer of corneal pathologies may be treated by deep anterior lamellar keratoplasty (DALK), and endothelial dysfunctions can be managed by posterior lamellar procedures such as Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) [ 6 , 7 , 8 ]. (intechopen.com)
To describe the results of therapeutic penetrating keratoplasty in patients with impending perforation or perforated infectious keratitis. (scielo.br)
In infectious keratitis with perforation or impending perforation that did not respond to conservative clinical therapy, therapeutic penetrating keratoplasty must be considered an alternative to erradicate infection and restore the ocular integrity. (scielo.br)
Descemet's stripping automated endothelial keratoplasty (DSAEK) using corneal donor tissue not acceptable for use in penetrating keratoplasty as a result of anterior stromal scars, pterygia, and previous corneal refractive surgical procedures. (biomedsearch.com)
PURPOSE: The purpose of this study was to evaluate outcomes of Descemet's stripping automated endothelial keratoplasty (DSAEK) using anterior stromal flawed (ASF) donor corneas that were unsuitable for use in full-thickness penetrating keratoplasty as a result of stromal scars, pterygia, or previous corneal refractive surgery and to compare results with DSAEK using standard tissue. (biomedsearch.com)
Femtosecond laser-assisted lamellar keratoplasty (FSLK) for anterior corneal stromal diseases. (centreforsight.com)
Intraocular pressure control and corneal graft survival after implantation of Ahmed valve device in high-risk penetrating keratoplasty. (centreforsight.com)
Compressive Cshaped lamelar keratoplasty: a surgical alternative for the management of severe astigmatism from peripheral corneal degeneration. (medigraphic.com)

Possible corneal manifestations are peripheral arcus lipoides-like opacifications, asymptomatic nebular dot-like opacities of the peripheral corneal epithelium, and central epithelial surface irregularities. (bmj.com)
Discussion: Erlotinib may be secreted into tear fluid and thereby adversely affect the corneal epithelium. (elsevier.com)
Underlying the corneal epithelium is a specialized region of collagen tissue. (nap.edu)
Any factor or agent that creates a breakdown of the corneal epithelium is a potential cause or risk factor for bacterial keratitis. (medscape.com)
By far the most common cause of trauma to the corneal epithelium and the main risk factor for bacterial keratitis is the use of contact lenses, particularly extended-wear contact lenses. (medscape.com)
Herpetic keratitis is inflammation of the corneal epithelium caused by herpes simplex virus infection. (aafp.org)
A keratocele, or descemetocele, is a herniation (perforation) of the Descemet membrane through the overlying corneal epithelium and supporting stroma. (news-medical.net)
this organism can pass through intact corneal epithelium. (college-optometrists.org)
Three weeks after NP-AMT, a rapid regression of the external inflammatory signs, progressive clearing of the membrane, and a closed corneal epithelium were noted in the right eye. (springer.com)
The corneas SHOW peripheral corneal thinning OU with an intact epithelium. (harvard.edu)
This condition is characterized by bilateral and symmetric corneal thinning with an intact epithelium. (harvard.edu)

Uncommon Necrotising interstitial keratitis: Characterised by stromal infiltrates, corneal thinning and possibly perforation. (wikipedia.org)
Our initial ocular examination showed bilateral intense conjunctival injection, corneal edema, diffuse corneal vascularization, and ring shaped stromal infiltration. (springer.com)
The Effect of Sodium Iodide on Stromal Loading, Distribution and Degradation of Riboflavin in a Rabbit Model of Transepithelial Corneal Crosslinking. (harvard.edu)
Quantitative analysis of corneal stromal riboflavin concentration without epithelial removal. (harvard.edu)
It can cause corneal epithelial defects, stromal thinning, and perforation. (harvard.edu)
Infected corneal ulcers can develop rapid stromal dissolution leading to globe perforation and iris prolapse. (akcchf.org)

56-year-old man was referred to the clinic for deep corneal scarring and vascularisation after a long history of neurotrophic keratitis, related with herpes infection in his right eye. (healio.com)
To identify predisposing factors leading to corneal perforation in patients with microbial keratitis. (bmj.com)
Eyes with corneal perforations generally have significant underlying pathology, such as corneal ulcers, trauma, serious infectious keratitis, or wound leaks, and are at high risk of further complications. (omic.com)
We report a fulminant case of nosocomial K. pneumoniae conjunctivitis complicated by infectious keratitis and corneal perforation in both eyes. (nus.edu.sg)
This rapidly progressed to severe infectious keratitis and corneal perforation in both eyes, despite intensive antibiotics to which the organism was susceptible. (nus.edu.sg)
Hence, topical steroid was applied on suspicion of phlyctenular keratitis and the patient 's symptoms and corneal lesion improved. (bvsalud.org)
Disciform Keratitis (Disciform Endotheliitis): a disc of corneal oedema, folds in Descemet's membrane, mild inflammation evident within the anterior chamber and fine keratic precipitates. (wikipedia.org)
As Aspergillus and Fusarium species are also major causes of corneal infection and blindness worldwide ( 6 ), the current study examined the role of hydrophobins in a murine model of fungal keratitis ( 7 , 8 ). (jimmunol.org)
Collectively, our results indicate that corneal P. aeruginosa infection induces a strong Th17-mediated corneal pathology, and treatment with endogenously derived protein such as Gal-1 may be of therapeutic value for the management of bacterial keratitis, a prevalent cause of vision loss and blindness in humans worldwide. (jimmunol.org)
Corneal infection with Pseudomonas aeruginosa is a leading cause of infectious microbial keratitis and associated vision impairment in humans worldwide ( 1 - 3 ). (jimmunol.org)
This bacterial keratitis is characterized by rapid inflammatory response with suppurative coagulative necrosis, often irreversibly damaging corneal tissue architecture, leading to vision loss ( 4 ). (jimmunol.org)

In this chapter, we discuss the role of AS-OCT on the basis of different corneal lamellar procedures such as DALK, DSAEK, and DMEK. (intechopen.com)
Severe astigmatism, impending perforation, or perforation may be treated with lamellar or eccentric penetrating corneal grafts. (harvard.edu)
Lamellar keratectomy, which removes thin layers of the corneal tissue. (petmd.com)
Management of Descemet Detachment following Crescentic Lamellar Excision with Autolamellar Dissection for Pellucid Marginal Corneal Degeneration. (centreforsight.com)
Lamellar crescentic resection for pellucid marginal corneal degeneration. (medigraphic.com)

And at the end of follow-up 90 days after the procedure, there were no relapses or additional perforations, the researchers reported online in JAMA Ophthalmology . (medpagetoday.com)
We present the first indication in ophthalmology of Tachosil(®) as an effective alternative in the treatment of sterile non-traumatic corneal perforations less than 1.5 mm in size. (sigmaaldrich.com)
METHOD: A 67-year-old woman was found to have a whorl-like corneal opacity on her visit to the Department of Ophthalmology. (biomedsearch.com)

In this case, despite the clinical treatment, the patient rapidly progressed into a bilateral corneal perforation. (escrs.org)

The treatment of corneal perforation depends on the location, severity and the cause of damage Tissue adhesive can be used to seal small perforation, but this method cannot be used to treat perforations larger than 1 mm. (wikipedia.org)
Golubovic S, Parunovic A. Cyanoacrylate glue in the treatment of corneal ulcerations. (springer.com)
Non-fixated amniotic patch within a flexible ring that is inserted like a contact lens has more recently been investigated for the treatment of corneal and ocular surface disorders. (wellmark.com)
The aim of this study is to access the efficacy and safety of UC-MSCs in the treatment of corneal burn in human. (clinicaltrials.gov)

To report the surgical approach, anatomical and functional results, and complications in the group of patients with corneal perforation. (hindawi.com)
The primary goal in repairing the corneal perforation is to achieve a watertight globe with structural integrity in order to prevent severe complications such as globe tissue prolapse, endophthalmitis, and glaucoma [ 1 , 3 ]. (hindawi.com)
Number of eyes with successful healing, time required for healing, status of corneal vascularization, and complications were compared in the two groups. (nih.gov)
Complications from contact lens use are the most common culprit in corneal ulcers in the United States, while agriculture-related injuries are the most common in India. (ucsf.edu)
NEW YORK (Reuters Health) - Patients with secondary Sjogren's syndrome (SS) are at increased risk of corneal complications compared to those with primary SS, and eyes with scleritis are at especially high risk of vision-threatening complications, according to new findings. (medscape.com)
Ten percent of the 1,838 eyes in the study had SVI, and 2.5% presented with corneal complications. (medscape.com)
Scleritis (OR, 8.86) and secondary SS (OR, 2.94) were independently associated with corneal complications. (medscape.com)
Patients with secondary SS and patients with scleritis "have a greater risk of developing sight-threatening corneal complications and therefore should be followed-up closely," they conclude. (medscape.com)
Its configuration creates an excluded gastric remnant, which is subject to potential acute complications such as bleeding, perforation, and necrosis. (springermedizin.de)
Complications included: 2 rejections, 6 recurrences, 13 glaucomas and 1 perforation. (scielo.br)

The patient presented acutely with corneal perforation in the left eye and, shortly thereafter, with corneal perforation with iris prolapse in the right eye. (escrs.org)

The approach sealed the perforations in all 11 patients included in the study, without any signs of inflammation or infection, according to Jorge Alió, MD, PhD, of Vissum Corporación Oftalmológica in Alicante, Spain, and colleagues. (medpagetoday.com)
Corneal perforations can be caused by trauma or ulcerative disease and "constitute a major ophthalmic emergency necessitating the intervention of corneal surgeons because of the severity and major consequences, such as infection, severe anatomic distortion of the anterior segment of the eye, retinal detachment, phthisis bulbi, and total blindness," according to the researchers. (medpagetoday.com)
The slit-lamp examination showed a central corneal perforation of 1mm in diameter, with no associated infection or inflammatory process. (sigmaaldrich.com)
The mechanisms of perforation included infection (n=17), trauma (n=1), autoimmune (n=6), ocular surface (n=5), surgical (n=4), and corneal ectasia (n=2). (arvojournals.org)
Even in desperate cases with corneal perforation greater than 3 mm and ocular infection, enucleation was avoided. (springer.com)
Identifying and treating the infection are important because gonococcal ophthalmia neonatorum can result in corneal scarring, ocular perforation, and blindness. (aafp.org)
To illustrate their serious health implications, six cases of contact lens-related corneal infection, in which sleeping in lenses was reported as the main risk factor, are presented. (cdc.gov)
Among the many behaviors that increase the risk for a contact lens-related corneal infection, sleeping in lenses is one of the riskiest and one of the most commonly reported behaviors among adolescent and adult contact lens wearers ( 3 ). (cdc.gov)
Using a murine model of A. fumigatus corneal infection, we showed that Δ rodA conidia induced significantly higher cytokine production, neutrophil infiltration, and more rapid fungal clearance from C57BL/6 corneas compared with the parent G10 strain, which was dependent on Dectin-1 and Dectin-2. (jimmunol.org)
Using a murine model of Aspergillus corneal infection, we also demonstrate that in the absence of RodA, A. fumigatus induces Dectin-1- and Dectin-2-dependent neutrophil recruitment to the corneal stroma and enhanced fungal killing. (jimmunol.org)
Corneal infection with Pseudomonas aeruginosa leads to a severe immunoinflammatory lesion, often causing vision impairment and blindness. (jimmunol.org)
Therefore, understanding the pathogenesis of P. aeruginosa corneal infection, particularly the different factors and cells that either contribute to or inhibit the corneal pathology, would reveal significant information to design novel therapeutics. (jimmunol.org)

Primary or secondary epithelial defects facilitate the development of corneal inflammation with subsequent perforation [ 1 , 2 ]. (hindawi.com)
In the left eye there was a descemetocele without corneal perforation or intraocular inflammation (Fig 1A). (bmj.com)
Descemetocele without corneal perforation or intraocular inflammation. (bmj.com)
During follow up the corneal infiltration and intraocular inflammation in the right eye slowly reduced. (bmj.com)
Furthermore, anti-inflammatory medications are successfully used to treat corneal ulcers that have produced inflammation. (news-medical.net)
We demonstrate in this study that local recombinant Gal-1 (rGal-1) treatment by subconjunctival injections significantly diminishes P. aeruginosa -mediated corneal inflammation through multiple mechanisms. (jimmunol.org)

Corneal transplantation combined with immuno-suppression led to a favorable outcome. (escrs.org)
Anterior segment optical coherence tomography (AS-OCT) is a valuable tool in corneal transplantation surgery. (intechopen.com)
Treatments of corneal disorders include medicines, corneal transplantation, and corneal laser surgery. (patientsville.com)
Nonpreserved amniotic membrane transplantation may be useful in relieving pain and improving corneal surface in anesthetic agent abusers. (springer.com)

Such eyes often require urgent corneal transplant surgery or other intraocular surgery, and treatment involves complex decision making. (omic.com)
Corneal Collagen Crosslinking which halts the progression of keratoconus and post-refractive surgery ectasia to help prevent worsening of vision and prevent the need for a corneal transplant in the future. (wakehealth.edu)
The following Dexagel Corneal Transplant side effect reports were submitted by healthcare professionals and consumers. (patientsville.com)
This information will help you understand how side effects, such as Corneal Transplant, can occur, and what you can do about them. (patientsville.com)
This Corneal Transplant side effect was reported by a consumer or non-health professional from GERMANY. (patientsville.com)
Use of human fibrin glue and amniotic membrane transplant in corneal perforation. (biomedsearch.com)

Various methods are used to treat them, including ocular adhesives, conjunctival flaps, heterologous amniotic membrane transplants, and corneal grafting. (medpagetoday.com)
The examination of the anterior segment showed a conjunctival chemosis, a diffuse and severe corneal thinning, dense annular infiltration and nasal microperforations occluded by the iris ( Figure 1 ). (scirp.org)
Foreign bodies and abrasions are the most common conjunctival and corneal injuries. (merckmanuals.com)

Pellucid marginal degeneration may cause corneal thinning, leading to perforation. (wikipedia.org)
Other conditions such as xerosis, exposure, neurotrophic disorders, corneal degeneration, and ectasia and surgical and toxic/keratolytic treatment can lead to corneal perforation. (hindawi.com)
This case represents an unusual, unilateral corneal ectatic disorder, most likely pellucid marginal degeneration. (acibadem.edu.tr)
Terrien's marginal corneal degeneration. (harvard.edu)
retinal pigment degeneration, corneal opacity. (mims.com)
Neurotrophic keratopathy (NK) is a corneal degeneration associated with corneal nerve dysfunction. (harvard.edu)
two cases reported presented corneal topography with peripheral inferior corneal slimming (pachymetry), flattening of superior and central meridian, high stigmatism against the rule, corroborating clinical pellucid marginal degeneration prognosis. (medigraphic.com)
In the cases studied, the pellucid marginal degeneration was presented with inferior corneal slimming, progressive irregular astigmatism and decreased visual acuity. (medigraphic.com)
Management of pellucid marginal corneal degeneration. (medigraphic.com)
Early pellucid marginal corneal degeneration: case reports of two refractive surgery candidates. (medigraphic.com)
Spontaneus corneal hydrops and perforation in keratoconus and pellucid marginal degeneration. (medigraphic.com)

Neurotrophic: corneal nerve damage causes persistent epithelial defect, thinning and even perforation. (wikipedia.org)
Owing to the pain in the right eye of our patient and persistent corneal epithelial defect decreased during the follow-up period, we performed NP-AMT on the left eye from another donor. (springer.com)

The authors present a case of severe gonococcal conjunctivitis associated with corneal perforation of the right eye in a 25-year-old homosexual man. (bmj.com)
The diagnosis of corneal perforation was then confirmed as a complication of conjunctivitis of gonococcal origin. (scirp.org)
Subsequently the conjunctivitis not being treated correctly resulted in the corneal perforation thanks to the proteolytic activity of the bacterium. (scirp.org)
Dacryoadenitis due to gonococcal conjunctivitis complicated by corneal perforation. (bioportfolio.com)

Success was determined by graft clarity at longest follow up or at last follow up prior to further corneal surgery. (arvojournals.org)
Multivariate regression was performed relating graft clarity to age, gender, etiology, time from perforation to surgery, use of glue, and surgical management (PK versus patch graft). (arvojournals.org)
Our study suggests that patients with corneal perforations who received patch grafts were more likely to maintain graft clarity at final follow up compared to those who underwent PKs. (arvojournals.org)
Hence, we performed an emergent tectonic corneal patch graft . (bvsalud.org)
Lin M., Talcott K.E., Lorch A.C. (2018) Case 28: Zone I/II Open Globe Injury with Corneal Patch Graft and Corneal Glue. (springer.com)
HAM graft that is fixated by sutures or glue or secured under a bandage contact lens is an established treatment for disorders for the corneal surface. (wellmark.com)
10 dogs and 3 cats with deep or full thickness corneal defects were treated surgically with BioSIS plus graft. (unboundmedicine.com)
Four-layer porcine SIS graft was successfully used for surgical treatment of deep corneal lesions in selected corneal diseases in a small series of dogs and cats, with good results in terms of mechanic support and corneal transparency. (unboundmedicine.com)

The primary aim of the study is to evaluate the clinical response of ST266 treated subjects with persistent corneal epithelial defects during 28 days of therapy. (clinicaltrials.gov)
Clinicians should diligently assess the corneal status in eyes with scleritis of SS patients such as the progression of SPKs on follow-up or development of small epithelial defects," Dr. Basu and colleagues state. (medscape.com)
The outcome is often poor, leading to persistent epithelial defects, corneal scarring, and perforations. (springer.com)

The procedure "is a safe and effective surgical alternative for the closure of corneal perforations," they wrote. (medpagetoday.com)
There is no one general-purpose surgical technique to treat corneal perforations. (hindawi.com)
A diagnosis of corneal perforation does not always require immediate surgical treatment. (hindawi.com)
Cyanoacrylate glue for corneal perforations: a description of a surgical technique and a review of the literature. (springer.com)
Perforating (full thickness) corneal lacerations are surgical emergencies. (acvs.org)
Disruption of the corneal membrane could also occur because of penetrating injury, surgical trauma or chemical injuries. (news-medical.net)
If the keratocele is associated with trauma, surgical techniques are more suitable, as also for those perforations that are very small or which do not heal despite medication. (news-medical.net)
This report of six contact lens-related corneal infections associated with sleeping in lenses demonstrates that corneal infections might require surgical intervention and result in corneal damage and possible permanent vision loss. (cdc.gov)

The initial ophthalmologic evaluation revealed visual acuity of hand movement in OU, and external examination allowed the evaluation of iridian herniation through the corneal melting (Fig. 2 ). (springeropen.com)
Researchers checked participants three months after the start of the trial, testing for visual acuity and corneal perforations. (ucsf.edu)
A perforation is suggested on examination by a Seidel test demonstrating an ocular leak, decreased visual acuity, decreased intraocular pressure, flattening of the anterior chamber, or changes in the contour of the iris or pupil. (aafp.org)

If the pain persists for months, however, it could lead to corneal perforation. (petmd.com)

We present four cases with corneal perforation. (escrs.org)
Our experience from the use of cyanoacrylate tissue adhesive in cases with corneal perforation greater than 3 mm is very encouraging. (springer.com)

Fibrin glue and cyanoacrylate tissue adhesive are both effective in the closure of corneal perforations up to 3 mm in diameter. (nih.gov)
Webster RG, Slansky HH, Refojo MF, Boruchoff SA, Dohlman CH. The use of adhesive for closure of corneal perforations. (springer.com)

Diagnosis of corneal perforation was made by slit-lamp examination in combination with the Seidel test. (biomedcentral.com)

Corneal perforation can be diagnosed by using the Seidel test . (wikipedia.org)
Any aqueous leakage is revealed during the Seidel test confirms corneal perforation. (wikipedia.org)
Apply fluorescein and examine the eye for the Seidel sign (disturbance of the surface fluorescein by a dark streaming of aqueous humor through a corneal or scleral perforation). (merckmanuals.com)

A UCSF study gives hope to those suffering from severe cases of bacterial corneal ulcers, which can lead to blindness if left untreated. (ucsf.edu)

Diseases that cause progressive corneal thinning. (wikipedia.org)
The patients, ranging in age from 23 to 82, had perforations stemming from severe corneal ulcerative diseases. (medpagetoday.com)
A puncture or hole through the CORNEAL STROMA resulting from various diseases or trauma. (uchicago.edu)

Preoperative AS-OCT imaging of recipient stroma can also predict Descemet membrane perforation during big bubble induction. (intechopen.com)

She had no history of rheumatoid arthritis, dry eyes, eye trauma, corneal surgery or neurotrophic keratopathy. (biomedcentral.com)

A 40-year-old male with a severe corneal melting, peripheral infiltration and nasal perforation in the right eye after a not affiliated case of urethritis is reported. (scirp.org)
Building on their findings, Acharya and her colleagues intend to continue their work, studying patients with even more severe corneal ulcers. (ucsf.edu)

After 36 hours of occlusion, a layer of fibrin covered the perforation, closing the defect. (sigmaaldrich.com)
If your cat undergoes the keratectomy procedure, its eye should be re-evaluated every seven to ten days, or until the corneal defect has healed. (petmd.com)

We describe the first case of recurrent severe bilateral corneal ulcerations with perforation in a female patient with keratosis follicularis. (bmj.com)
Ocular involvement is frequent, typically in the form of necrotizing nodular episcleritis, peripheral corneal ulcerations, and retinal vasculitis. (springeropen.com)
Pseudomonal eye infections can lead to corneal perforations and ulcerations, endophthalmitis, and orbital cellulitis. (medscape.com)

Although not previously reported, K. pneumoniae can cause devastating keratoconjunctivitis resulting in corneal melt, perforation, and uncontrolled endophthalmitis. (nus.edu.sg)

In the immediate post-surgery period, the amniotic membrane remained in position and the chamber was reshaped with the tissue adhesive covering the perforation on its endothelial side. (escrs.org)

Spontaneous perforation or perforation due to minor trauma occurs in approximately 15% of patients. (harvard.edu)
Corneal ulcers usually occur secondary to trauma, but may also occur secondary to lack of tear production, eyelid abnormalities or nerve damage. (akcchf.org)

Examination of the left eye revealed corneal staining and thinning at the 6 o'clock position. (bmj.com)
Slitlamp examination demonstrated peripheral corneal edema extending between the 2 and 6 o'clock positions as well as a perforation located inferiorly. (acibadem.edu.tr)

Limitations of the study include inherent selection bias of a retrospective review and lack of clinical documentation of perforation measurement. (arvojournals.org)
This report is important to gain more information about corneal perforation clinical presentation in neonates, Investigation, and management. (medworm.com)

To describe the efficacy of four-layer porcine small intestinal submucosa (Vetrix BioSIS plus+) as single scaffold for the treatment of deep corneal lesions in dogs and cats. (unboundmedicine.com)

Biomicroscopy assessment showed bilateral corneal ulcers, in OD inferior-paracentral located with iris exposure and in OS centrally located with iris exposure, mild corneal edema and athalamia (Fig. 3 ), non-reactive pupils, and nuclear lens sclerosis in both eyes. (springeropen.com)
1991). When doses exceed 200 mg·min/m 3 , however, corneal edema or swelling occurs. (nap.edu)

Purpose: To report a case of corneal perforation associated with oral administration of erlotinib and its spontaneous healing after temporary discontinuation of drug treatment. (elsevier.com)
Spontaneous corneal perforation in a pat. (acibadem.edu.tr)

In this retrospective consecutive case series, 15 eyes of 15 patients with eccentric corneal perforations underwent small-diameter penetrating keratoplasties with glycerin-cryopreserved grafts. (unboundmedicine.com)
The corneal grafts used in this study were 2.5-4.5 mm in size and preserved at -20 degrees C in pure glycerin for 6 months to 5 years. (unboundmedicine.com)

247 eyes with corneal perforation were operated on between January 2010 and July 2016. (hindawi.com)

Various factors cause prolonged degradation of the ECM, which sometimes leads to corneal perforation. (biomedcentral.com)
The anatomy of brachycephalic dogs with prominent, frontally placed globes leads to corneal exposure. (akcchf.org)

Management of nontraumatic corneal perforation with tectonic drape patch and cyanoacrylate glue. (springer.com)

Seven patients were included, including 3 hemorrhages, two of which were treated with double-balloon enteroscopy, as well as 3 perforations and 1 necrosis, all of which required emergent surgery. (springermedizin.de)

Tissue adhesive can be used to seal small perforation, but this method cannot be used to treat perforations larger than 1 mm. (wikipedia.org)
Does my Surgery Class 1 rating cover me for sealing corneal perforations with tissue adhesive? (omic.com)
For these reasons, coverage for sealing corneal perforations with tissue adhesive is not included within the Surgery Class 1 rate. (omic.com)
After 3-4 weeks, the tissue adhesive had dissolved completely and the perforation had sealed. (escrs.org)
de Juan E. Sodium hyalouronate and tissue adhesive in treating corneal perforations. (springer.com)

It allows visualizing the shape and depth of corneal lesions such as scarring, measuring central corneal thickness, and lesion size [ 11 , 12 ]. (intechopen.com)
Central corneal thickness measurements should be performed before cutting to avoid tissue perforation. (biomedsearch.com)

Fibrin glue provides faster healing and induces significantly less corneal vascularization, but it requires a significantly longer time for adhesive plug formation. (nih.gov)

The incidence of Descemet's membrane perforation during DALK varies from 4% to 40%, and depends on the technique and the programmed depth. (healio.com)

A. Ocular perforation. (aafp.org)

The attempt to bare DM can be complicated by its perforation which can cause collection of aqueous at the recipient-donor interface (double anterior chamber) 1 . (healio.com)
2-4 When a DM perforation occurs during surgery, air injection into the anterior chamber should be performed at the end of the procedure. (healio.com)
We report a case of a DM perforation during DALK, detected on the first-postoperative day as a double anterior chamber which was successfully treated with an intracameral injection of sulphur hexafluoride (SF 6 ) in isoexpansile concentration. (healio.com)
The use of these adhesives in the anterior chamber is an useful and easily solution for treating small corneal perforation. (escrs.org)
Complication were partial collagenolysis in three cases (25 per cent), which resolved with medical therapy, mild corneal pigmentation in one case (8.4 per cent) and anterior synechia in one case (8.4 per cent). (unboundmedicine.com)

The perforations were sealed in all patients, with the fibrin membrane disappearing after the first 3 to 5 days. (medpagetoday.com)
Seven of the patients ultimately underwent definite corneal grafting. (medpagetoday.com)
Forty-one patients (41 eyes) with corneal perforations up to 3 mm in diameter with a positive Seidel's test were randomly assigned to two groups (1 and 2). (nih.gov)
Two groups of 60 patients each, with perforated corneal ulcers and healed/healing corneal ulcers, respectively, were recruited in a case-control study conducted in northern India. (bmj.com)
The development of corneal epithelial disorders in patients receiving this drug may be reversed by reducing its dose. (elsevier.com)
However, it helped patients who had more serious forms of bacterial corneal ulcers, according to UCSF researchers. (ucsf.edu)
Intraoperative OCT pachymetry in patients undergoing dextran-free riboflavin UVA accelerated corneal collagen crosslinking. (centreforsight.com)
Corneal topographic and pachymetric screening of keratorefractive patients. (medigraphic.com)

To compare the efficacy of fibrin glue and N-butyl-2-cyanoacrylate in corneal perforations. (nih.gov)
Corneal perforations managed non-surgically with glue, and cases of primary closure were excluded. (arvojournals.org)
To show the utility of intracameral fibrin glue in corneal perforation. (escrs.org)
In these cases a running 10.0 nylon suture was used to create a reticulum over the space of the corneal perforation upon which the glue was applied. (springer.com)
A common method for treating small perforations with certain specific features is through the application of glue. (news-medical.net)

Anatomy1

Organisms4

Diseases27

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Psychiatry and Psychology2

Phenomena and Processes1

Technology, Industry, Agriculture3

Humanities1

Information Science1

Enhancing effects of sericin on corneal wound healing in Otsuka Long-Evans Tokushima fatty rats as a model of human type 2 diabetes. (1/15)

Corneal perforation with preseptal cellulitis in a patient with acute lymphocytic leukemia. (2/15)

One cornea for two patients: case report. (3/15)

Four cases of corneal perforation in patients with chronic graft-versus-host disease. (4/15)

Tectonic deep anterior lamellar keratoplasty in impending corneal perforation using cryopreserved cornea. (5/15)

VIP and growth factors in the infected cornea. (6/15)

Synthetic fiber from a teddy bear causing keratitis and conjunctival granuloma: case report. (7/15)

Superimposed fungal ulcer after fibrin glue sealant in infectious corneal ulcer. (8/15)

Corneal Perforation

Corneal Ulcer

Eye Injuries, Penetrating

Intestinal Perforation

Eye Infections, Bacterial

Corneal Diseases

Eye Infections, Fungal

Keratitis

Keratoplasty, Penetrating

Rupture, Spontaneous

Cornea

Esophageal Perforation

Eye Infections

Contact Lenses

Serratia Infections

Tissue Adhesives

Pseudomonas Infections

Tympanic Membrane Perforation

Uterine Perforation

Peptic Ulcer Perforation

Visual Acuity

Administration, Topical

Pseudomonas aeruginosa

Pneumoperitoneum

Stomach Rupture

Encyclopedias as Topic

Cyanoacrylates

Enbucrilate

Fibrin Tissue Adhesive

Fibrin

Corneal Transplantation

Conjunctivitis, Bacterial

Neisseria gonorrhoeae

Scleritis

Optic Neuropathy, Ischemic

Entropion

Retinal Vasculitis

Dacryocystitis

Restless Legs Syndrome

Lissamine Green Dyes

Dry Eye Syndromes

Literature, Modern

Eucommiaceae

Stevens-Johnson Syndrome

Ilex

Enhancing effects of sericin on corneal wound healing in Otsuka Long-Evans Tokushima fatty rats as a model of human type 2 diabetes. (1/15)

Corneal perforation with preseptal cellulitis in a patient with acute lymphocytic leukemia. (2/15)

One cornea for two patients: case report. (3/15)

Four cases of corneal perforation in patients with chronic graft-versus-host disease. (4/15)

Tectonic deep anterior lamellar keratoplasty in impending corneal perforation using cryopreserved cornea. (5/15)

VIP and growth factors in the infected cornea. (6/15)

Synthetic fiber from a teddy bear causing keratitis and conjunctival granuloma: case report. (7/15)

Superimposed fungal ulcer after fibrin glue sealant in infectious corneal ulcer. (8/15)

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