Corneal Opacity
Trichiasis
Cataract
Cornea
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
Lecithin Acyltransferase Deficiency
An autosomal recessively inherited disorder caused by mutation of LECITHIN CHOLESTEROL ACYLTRANSFERASE that facilitates the esterification of lipoprotein cholesterol and subsequent removal from peripheral tissues to the liver. This defect results in low HDL-cholesterol level in blood and accumulation of free cholesterol in tissue leading to a triad of CORNEAL OPACITY, hemolytic anemia (ANEMIA, HEMOLYTIC), and PROTEINURIA.
Entropion
Corneal Dystrophies, Hereditary
Blindness
Surgery, Plastic
Tattooing
Corneal Stroma
Keratoplasty, Penetrating
Visual Acuity
Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.
Pupil Disorders
Photorefractive Keratectomy
Esthetics
Microscopy, Acoustic
A scientific tool based on ULTRASONOGRAPHY and used not only for the observation of microstructure in metalwork but also in living tissue. In biomedical application, the acoustic propagation speed in normal and abnormal tissues can be quantified to distinguish their tissue elasticity and other properties.
Corneal Neovascularization
New blood vessels originating from the corneal veins and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.
Vision, Low
Vision considered to be inferior to normal vision as represented by accepted standards of acuity, field of vision, or motility. Low vision generally refers to visual disorders that are caused by diseases that cannot be corrected by refraction (e.g., MACULAR DEGENERATION; RETINITIS PIGMENTOSA; DIABETIC RETINOPATHY, etc.).
Keratan Sulfate
A sulfated mucopolysaccharide initially isolated from bovine cornea. At least two types are known. Type I, found mostly in the cornea, contains D-galactose and D-glucosamine-6-O-sulfate as the repeating unit; type II, found in skeletal tissues, contains D-galactose and D-galactosamine-6-O-sulfate as the repeating unit.
Anterior Eye Segment
Keratitis, Herpetic
Lasers, Excimer
Gas lasers with excited dimers (i.e., excimers) as the active medium. The most commonly used are rare gas monohalides (e.g., argon fluoride, xenon chloride). Their principal emission wavelengths are in the ultraviolet range and depend on the monohalide used (e.g., 193 nm for ArF, 308 nm for Xe Cl). These lasers are operated in pulsed and Q-switched modes and used in photoablative decomposition involving actual removal of tissue. (UMDNS, 2005)
Lens Cortex, Crystalline
Corneal Transplantation
Vision Disorders
Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from EYE DISEASES; OPTIC NERVE DISEASES; VISUAL PATHWAY diseases; OCCIPITAL LOBE diseases; OCULAR MOTILITY DISORDERS; and other conditions (From Newell, Ophthalmology: Principles and Concepts, 7th ed, p132).
Epithelium, Corneal
Eye
Phosphatidylcholine-Sterol O-Acyltransferase
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC 2.3.1.43.
Phenotype
Biological Ontologies
Internet
Phacoemulsification
A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)
Ophthalmology
Lens Implantation, Intraocular
Phenotype of autosomal recessive congenital microphthalmia mapping to chromosome 14q32. (1/277)
BACKGROUND: Congenital microphthalmia (OMIM: 309700) may occur in isolation or in association with a variety of systemic malformations. Isolated microphthalmia may be inherited as an autosomal dominant, an autosomal recessive, or an X linked trait. METHODS: Based on a whole genome linkage analysis, in a six generation consanguineous family with autosomal recessive inheritance, the first locus for isolated microphthalmia was mapped to chromosome 14q32. Eight members of this family underwent clinical examination to determine the nature of the microphthalmia phenotype associated with this locus. RESULTS: All affected individuals in this family suffered from bilateral microphthalmia in association with anterior segment abnormalities, and the best visual acuity achieved was "perception of light". Corneal changes included partial or complete congenital sclerocornea, and the later development of corneal vascularisation and anterior staphyloma. Intraocular pressure, as measured by Schiotz tonometry, was greatly elevated in many cases. CONCLUSIONS: This combination of ocular defects suggests an embryological disorder involving tissues derived from both the neuroectoderm and neural crest. Other families with defects in the microphthalmia gene located on 14q32 may have a similar ocular phenotype aiding their identification. (+info)A first British case of fish-eye disease presenting at age 75 years: a double heterozygote for defined and new mutations affecting LCAT structure and expression. (2/277)
Fish-eye disease is a familial syndrome with corneal opacification, major high density lipoprotein (HDL) deficiency in plasma, significant cholesterol esterification in plasma on non-HDL lipoproteins, generally without premature coronary disease. This first British male case from unrelated British parents had infarcts when aged 49 and 73 years but was asymptomatic at age 81 years, with plasma cholesterol 4.3-7.1 mmol/litre, triglycerides 1.8-2.2 mmol/litre, HDL cholesterol < 0.1 mmol/litre, apolipoprotein A-I < 0.16 g/litre, lipoprotein(a) 0.61 g/litre. Cholesterol esterification was impaired using HDL-3 and A-I proteoliposomes but not using VLDL/IDL/LDL. The findings are those of LCAT deficiency with the classic fish-eye disease defect. Most of the 22 reported cases were homozygous or heterozygous for a Thr-Ile mutation at codon 123 of the lecithin:cholesterol acyltransferase (LCAT) gene. This patient was a double heterozygote for this mutation and a second new incompletely defined mutation affecting LCAT expression as defined by reduced mass and activity in plasma. (+info)Functional human corneal equivalents constructed from cell lines. (3/277)
Human corneal equivalents comprising the three main layers of the cornea (epithelium, stroma, and endothelium) were constructed. Each cellular layer was fabricated from immortalized human corneal cells that were screened for use on the basis of morphological, biochemical, and electrophysiological similarity to their natural counterparts. The resulting corneal equivalents mimicked human corneas in key physical and physiological functions, including morphology, biochemical marker expression, transparency, ion and fluid transport, and gene expression. Morphological and functional equivalents to human corneas that can be produced in vitro have immediate applications in toxicity and drug efficacy testing, and form the basis for future development of implantable tissues. (+info)Persistent corneal haze after excimer laser photokeratectomy in plasminogen-deficient mice. (4/277)
PURPOSE: Excimer laser photorefractive keratectomy creates a nonvascular wound of the cornea. Fibrin deposition and resolution after excimer laser photokeratectomy were investigated in relation to corneal repair and restoration of clarity in mice with a genetic deficiency of plasminogen. METHODS: A Summit Apex Laser (Summit, Waltham, MA) was used to perform 2-mm, 175-pulse, transepithelial photoablations that resulted in deep stromal keratectomies. Photokeratectomy was performed on the corneas of plasminogen-deficient (Plg-/-) mice and littermate control animals. Eyes were examined for re-epithelialization and clarity throughout the 21-day observational period. Histologic sections were taken during the observational period and fibrin(ogen) was detected immunohistochemically. RESULTS: Re-epithelialization was rapid and complete within 3 days in both control and Plg-/- animals. Exuberant corneal fibrin(ogen) deposition was noted in Plg-/- mice and sparse fibrin(ogen) deposition in control mice on days 1 and 3 after injury. Fibrin(ogen) deposits resolved in control mice but persisted in Plg-/- mice (74% of eyes at 21 days; P < 0.004). Corneal opacification, scarring, and the presence of anterior chamber fibrin(ogen) occurred in plasminogen-deficient mice but not in control mice. CONCLUSIONS: Fibrin(ogen) deposition occurs during corneal wound repair after photokeratectomy. Impaired fibrinolysis in Plg-/- mice caused persistent stromal fibrin deposits that correlated with the development of corneal opacity. (+info)Relationship between structure and biochemical phenotype of lecithin:cholesterol acyltransferase (LCAT) mutants causing fish-eye disease. (5/277)
In order to test the hypothesis that fish-eye disease (FED) is due to a deficient activation of lecithin:cholesterol acyltransferase (LCAT) by its co-factor apolipoprotein (apo) A-I, we overexpressed the natural mutants T123I, N131D, N391S, and other engineered mutants in Cos-1 cells. Esterase activity was measured on a monomeric phospholipid enelogue, phospholipase A(2) activity was measured on reconstituted high density lipoprotein (HDL), and acyltransferase activity was measured both on rHDL and on low density lipoprotein (LDL). The natural FED mutants have decreased phospholipase A(2) activity on rHDL, which accounts for the decreased acyltransferase activity previously reported. All mutants engineered at positions 131 and 391 had decreased esterase activity on a monomeric substrate and decreased acyltransferase activity on LDL. In contrast, mutations at position 123 preserved these activities and specifically decreased phospholipase A(2) and acyltransferase activites on rHDL. Mutations of hydrophilic residues in amphipathic helices alpha 3;-4 and alpha His to an alanine did not affect the mutants' activity on rHDL. Based upon the 3D model built for human LCAT, we designed a new mutant F382A, which had a biochemical phenotype similar to the natural T123I FED mutant. These data suggest that residues T123 and F382, located N-terminal of helices alpha 3-4 and alpha His, contribute specifically to the interaction of LCAT with HDL and possibly with its co-factor apoA-I. Residues N131 and N391 seem critical for the optimal orientation of the two amphipathic helices necessary for the recognition of a lipoprotein substrate by the enzyme. (+info)Ocular changes in beagle dogs following oral administration of CGS 24565, a potential hypolipidemic agent. (6/277)
(11R)-N,15-dideoxo-1-deoxy-1,15-epoxy-11-hydroxy-4-0methy l-8-0-(2, 2-dimethyl-1-oxopropyl)-3-[4- inverted question mark(2,4, 6-trimethylphenyl)methyl inverted question mark-1-piperazinyl]rifamycin has been evaluated as a potential hypolipidemic agent. As part of a safety evaluation program, a 3-month oral toxicity study was performed in which CGS 24565 was administered to beagle dogs via gelatin capsules at 10, 50, or 300 mg/kg/day. Ophthalmoscopic examinations (using focal illumination and indirect opthalmoscopy) on day 83 (week 12) revealed bilateral adnexal and corneal changes affecting 5 dogs (3 males, 2 females, 300 mg/kg/day). Ophthalmoscopically, dogs from the 300 mg/kg dose level exhibited the adnexal changes characterized as ptosis, conjunctivitis, episcleritis, and relaxed membrane nictitans, while the corneal changes were characterized as posterior stromal edema (cloudy, diffuse opacity usually accompanied by deep neovascularization; the diffuse edema masked the complete evaluation of other ocular structures) and stromal infiltrates in the area of Decement's membrane (appeared to be multifocal, polymorphic changes/alterations in Decement's membrane, or endothelial swelling). No changes from normal were seen clinically in the eyes of other dogs on this experiment. In those dogs affected by the ocular changes caused by CGS 24565, a visual deficit in acuity was suspected. The corneal changes, as manifested, were suggestive of permanent, irreversible corneal damage. Subsequent ophthalmoscopic examinations performed at established intervals during weeks 15 through 26, revealed abatement of the adnexal changes, while the corneal changes, as described above, remained generally unchanged, confirming irreversibility of the corneal changes within the recovery period of 13 weeks. Light microscopy confirmed irreversible corneal neovascularization, vacuolar degeneration of the keratocytes at 300 mg/kg, and polymorphic infiltrates in the region of Decement's membrane. The results demonstrate that the cornea was the target tissue of toxicity for CGS 24565, and indicated that the findings represent a significant toxic effect. The correlation of histopathological findings support the hypothesis of the diagnosis of interstitial stromal degeneration/atrophy. The potential for a similar result to the cornea of humans does exist. Due to these changes and other toxic effects associated with this class of compound, further development was terminated. (+info)A simple method to evaluate the massive dose vitamin A prophylaxis program in preschool children. (7/277)
A massive dose vitamin A prophylaxis program is currently in operation in several States of India. Evaluation of this program on a large scale has so far been difficult due to lack of baseline data on the prevalence of vitamin A deficiency in children. In this study, a simple evaluation method which makes use of the linear relationship that exists between age on one hand and prevalence of ocular signs of vitamin A deficiency (Bitot's spots) on the other is described. Regression coefficients between age and prevalence of vitamin A deficiency of areas not covered by the program (control areas) were found to be significantly different both from zero and from regression coefficients of regularly covered areas (experimental areas). Also, all regression lines of control areas were found to be above the regression zone of experimental areas. These differences between the experimental and control areas which were significant, indicate the impact of the program in areas where the program is in operation. The regression coefficient calculated for one area where the program was discontinued after some time was found to be significantly different from zero, also it was different from the regression zone of the experimental areas. However, the regression coefficient of the discontinued area was found to be significantly different from the experimental areas only at 10% level, indicating a lesser degree of efficiency of the program in this area as compared to regularly fed areas. It is, therefore, suggested that evaluation of the massive dose prophylaxis program be done against the null hypothesis beta = 0.0065--the regression coefficient achievable under field conditions. (+info)Excimer laser phototherapeutic keratectomy: indications, results and its role in the Indian scenario. (8/277)
PURPOSE: To report indications, technique, and results of excimer phototherapeutic keratectomy (PTK), and describe possible reasons for the small numbers of such procedures performed in a referral institute in India. METHODS: Retrospective review of case records of 10 patients (11 eyes) who underwent excimer PTK at our institute between February 1994 and September 1997. RESULTS: Corneal scars were the most common indication for treatment. Best-corrected visual acuity (BCVA) improved in 6 eyes (mean: 2 lines of Snellen acuity). All eyes had BCVA > or = 6/12 after treatment. None of the patients experienced loss of BCVA after treatment. Unaided visual acuity improved in 3 eyes and decreased in 2 eyes. Change in spherical equivalent refraction > or = 1 diopter occurred in 77.8% of eyes after treatment. Treating central corneal scars resulted in a significant hyperopic shift in refraction. CONCLUSIONS: Excimer PTK is a safe and effective procedure for the treatment of superficial corneal opacities. Post-treatment ametropia may require further correction with optical aids. Inappropriate referrals, deep corneal scars, and cost of the procedure could have contributed to the small numbers of PTK performed at our institute. Improved understanding of procedural strengths and limitations could lead to increased use of this procedure, with satisfying results in selected patients. (+info)
Ocular Pathology: Band Keratopathy
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ICD-9-CM Diagnosis Codes 371.* : Corneal opacity and other disorders of cornea
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Lecithin-cholesterol acyltransferase
LCAT deficiency can cause impaired vision due to cholesterol corneal opacities, anemia, and kidney damage. It belongs to the ... Cogan DG, Kruth HS, Datilis MB, Martin N (1993). "Corneal opacity in LCAT disease". Cornea. 11 (6): 595-9. doi:10.1097/00003226 ...
Isotretinoin
... development of corneal opacities, inflammation of the cornea (keratitis), swelling of the optic disk (papilloedema, associated ...
OCT Biomicroscopy
High-speed optical coherence tomography of corneal opacities. Ophthalmology. 2007 Jul;114(7):1278-85. Plesea et al. Direct ... corneal elevation measurements using multiple delay en face optical coherence tomography. J Biomed Opt. 2008 Sep-Oct;13(5): ... have demonstrated the ability of OCT systems to depict pathology within the cornea as well as disorders of corneal topography. ...
Primary juvenile glaucoma
Corneal opacity that results from hereditary dystrophies is usually symmetric. Corneal enlargement may result from megalocornea ... Buphthalmos and Haab's striae can often be seen in case of congenital glaucoma.[citation needed] Corneal cloudiness may have ... The typical infant who has congenital glaucoma usually is initially referred to an ophthalmologist because of apparent corneal ... The commonly described triad of epiphora (excessive tearing), blepharospasm and photophobia may be missed until the corneal ...
Cockayne syndrome
Cataracts and cloudiness of the cornea (corneal opacity) are common. The loss of and damage to the nerves of the optic nerve, ...
Red eye (medicine)
... corneal abnormalities including edema or opacities ("corneal haze") corneal staining abnormal pupil size abnormal intraocular ... usually from corneal edema, or they may be localized in the case of corneal ulcer or keratitis. Corneal epithelial disruptions ... In rare instances, this opacity is congenital. In some, there is a family history of corneal growth disorders which may be ... Rezende RA, Uchoa UB, Uchoa R, Rapuano CJ, Laibson PR, Cohen EJ (2004). "Congenital corneal opacities in a cornea referral ...
Arthur Groenouw
Characterized by discrete grey opacities scattered over the surface of the cornea. "Groenouw Type II": Macular type of corneal ... Later on, his findings on corneal dystrophy were classified as two separate syndromes: "Groenouw Type I": Granular type of ... In 1890 Groenouw described two different types of corneal dystrophy, of which he wrote about in an article titled " ... "Immunohistochemistry and Electron Microscopy of Early-Onset Fuchs Corneal Dystrophy in Three Cases with the Same L450W Col8A2 ...
Adenoviral keratoconjunctivitis
Corneal opacities, the hallmark of the chronic phase, are usually self-limited. They may occur as numular keratitis. Topical ... Topical cidofovir is the first antiviral agent which has effectively reduced the incidence of corneal opacities, but local ... Topical cyclosporin A (CsA) appears to be effective in the treatment of persistent corneal opacities. Topical interferon might ... conjunctival inflammation of varying intensity with or without corneal involvement and a chronic phase with corneal opacities. ...
Philipp Franz von Walther
In the treatise Ueber die Hornhautflecken, he gave an early account of corneal opacity. With Karl Ferdinand von Gräfe (1787- ...
Phototherapeutic keratectomy
The common indications for PTK are corneal dystrophies, scars, opacities, and bullous keratopathy. [PTK in the developing world ... PTK allows the removal of superficial corneal opacities and surface irregularities. It is similar to photorefractive ... http://www.ophthalmologyweb.com/JournalUpdates.aspx?spid=23&jid=15009 "Facts About The Cornea and Corneal Disease" - National ...
List of dog diseases
Corneal diseases Corneal dystrophy is a condition characterized by bilateral, noninflammatory opacity of the cornea. It appears ... Corneal dystrophy can also have a crystalline appearance. Corneal ulcer, or ulcerative keratitis, is an inflammatory condition ... Other eye conditions can cause corneal ulcers, such as entropion, distichia, corneal dystrophy, and keratoconjunctivitis sicca ... Lens diseases Cataracts* are an opacity in the lens of the eye. Most cataracts in dogs are caused by a genetic predisposition, ...
Exposure keratopathy
It can lead to corneal ulceration and permanent loss of vision due to corneal opacity. Normally, corneal surface is kept moist ... This will lead to corneal epithelial damage. Both tear film and corneal epithelium play significant role in corneal protective ... If corneal ulcer is detected, it may be treated medically with antibiotics. If corneal perforation has occurred, immediate ... Punctate epithelial defects, epithelial break down and stromal melting may be seen in corneal examination. Corneal ulceration ...
Lumican
... skin fragility and corneal opacity in the absence of lumican". The Journal of Cell Biology. 141 (5): 1277-86. doi:10.1083/jcb. ... Rada JA, Cornuet PK, Hassell JR (Jun 1993). "Regulation of corneal collagen fibrillogenesis in vitro by corneal proteoglycan ( ... Corneal transparency is possible due to the exact alignment of collagen fibers by lumican (and keratocan) in the intrafibrillar ... Mice that have the lumican gene knocked out (Lum-/-) develop opacities of the cornea in both eyes and fragile skin. The lumican ...
GM1 gangliosidoses
Macular cherry-red spots in 50% by 6-10 months; corneal opacities in some Facial dysmorphology: frontal bossing, wide nasal ... corneal clouding in some patients, and dystonia (sustained muscle contractions that cause twisting and repetitive movements or ...
Trachoma
Corneal opacity (CO)-Corneal opacity blurring part of the pupil margin Although trachoma was eliminated from much of the ... These lashes can lead to corneal opacities and scarring and then to blindness. Linear scar present in the sulcus subtarsalis is ... The major complication or the most important one is corneal ulcer occurring due to rubbing by concentrations, or trichiasis ...
East Coast fever
Pathology includes anorexia, dyspnea, corneal opacity, nasal discharge, frothy nasal discharge, diarrhea, pulmonary edema, ...
Persistent pupillary membrane
Attachment to the cornea can cause small corneal opacities, while attachment to the lens can cause small cataracts. Using ...
CSRP2BP
Animals of both sex also had corneal opacity and spinal abnormalities (including scoliosis and fusion of vertebral arches). ...
Winchester syndrome
... corneal opacities) which can cause problems with vision. Winchester syndrome is believed to be inherited through autosomal ... opacities in the cornea, coarse facial features, dissolution of the carpal and tarsal bones (in the hands and feet, ...
Infectious bovine keratoconjunctivitis
... corneal opacity, and ulceration. This disease is highly contagious and occurs worldwide. Younger animals are more susceptible, ... UV light also directly damages the corneal epithelium, leading to a breakdown in host innate immunity. Dust, dried-up plants, ... Anti-inflammatory therapy can help shorten recovery times, but topical corticosteroids should be used with care if corneal ... and corneal ulceration. Cattle show signs of pain, increased lacrimation, excessive blinking, and conjunctivitis. More severe ...
TGFBI
1998). "A new L527R mutation of the betaIGH3 gene in patients with lattice corneal dystrophy with deep stromal opacities". Hum ... Klintworth GK (2009). "Corneal dystrophies". Orphanet J Rare Dis. 4 (1): 7. doi:10.1186/1750-1172-4-7. PMC 2695576. PMID ... 1998). "Granular corneal dystrophy with homozygous mutations in the kerato-epithelin gene". Am. J. Ophthalmol. 126 (2): 169-76 ... 2000). "A common beta ig-h3 gene mutation (delta f540) in a large cohort of Sardinian Reis Bücklers corneal dystrophy patients ...
Emmonsia parva
This opacification may extend to other distal parts of the eye such as the limbus and angular corneal opacities. Granulomas ...
Medical ultrasound
It is commonly used to see inside the eye when media is hazy due to cataract or any corneal opacity. Modern ultrasound is used ...
Galactosemic cataract
April 2008). "Clinical variability of autosomal dominant cataract, microcornea and corneal opacity and novel mutation in the ... A cataract is an opacity that develops in the crystalline lens of the eye. The word cataract literally means, "curtain of water ... so the term may have been used metaphorically to describe the similar appearance between mature ocular opacities and water fall ...
Keratoendotheliitis fugax hereditaria
The opacities may be associated with decreased visual acuity, but they have not been severe enough to need corneal ... to central corneal stromal opacities. Approximately 50 known cases have been reported in the literature. The disease so far has ... The repeated corneal inflammation over time can lead to reduced visual acuity. Keratoendotheliitis fugax hereditaria was first ... During the acute symptoms, a slit lamp shows pseudoguttae, dark patches in the corneal endothelium, thought to represent patchy ...
Lecithin cholesterol acyltransferase deficiency
Symptoms of the familial form include visual impairment caused by diffuse corneal opacities, target cell hemolytic anemia, and ... Corneal transplant may be considered for patients presenting with severely impaired vision caused by cholesterol corneal ... major cause of morbidity is visual impairment due to corneal opacity. These patients have low HDL cholesterol but surprisingly ... Fish-eye disease is less severe and most commonly presents with impaired vision due to corneal opacification. It rarely ...
Red reflex
It is also used to detect opacities in the visual axis, such as a cataract or corneal abnormality. The inequality of red ...
Wilsonen eritasuna, entziklopedia askea.
metabolic disease with corneal opacity (en) , supranuclear oculomotor palsy (en) , dardara, rare genetic tremor disorder (en) ...
Arcus senilis
It is the most common peripheral corneal opacity, and is usually found in the elderly where it is considered a benign condition ... Limbus sign is caused by dystrophic calcification at the corneal limbus, and can be confused with AS in geriatric populations. ... AS is caused by leakage of lipoproteins from limbal capillaries into the corneal stroma. Deposits have been found to consist ... Chambless LE, Fuchs FD, Linn S, Kritchevsky SB, Larosa JC, Segal P, Rifkind BM (October 1990). "The association of corneal ...
Anterior segment mesenchymal dysgenesis
... associated with an increased risk of glaucoma and corneal opacity. Peters' (frequently misspelled as Peter's) anomaly is a ... adhesions of the iris and cornea and abnormalities of the posterior corneal stroma, Descemet's membrane, corneal endothelium, ... anomaly complicated by a corneal tattoo". Optometry and Vision Science. 75 (9): 635-639. doi:10.1097/00006324-199809000-00017. ... specific type of mesenchymal anterior segment dysgenesis, in which there is central corneal leukoma, ...
Visual impairment
As a result, corneal scarring from all causes is now the fourth greatest cause of global blindness.[37] ... Cataracts: is the congenital and pediatric pathology that describes the greying or opacity of the crystalline lens, which is ... Central corneal ulceration is also a significant cause of monocular blindness worldwide, accounting for an estimated 850,000 ... corneal clouding, childhood blindness, and a number of infections.[6] Visual impairment can also be caused by problems in the ...
Corneal dystrophy
... corneal dystrophies should be suspected when corneal transparency is lost or corneal opacities occur spontaneously, ... Lisch epithelial corneal dystrophy is characterized by feather shaped opacities and microcysts in the corneal epithelium that ... Corneal stromal dystrophies - Macular corneal dystrophy is manifested by a progressive dense cloudiness of the entire corneal ... The hallmark of Schnyder corneal dystrophy is the accumulation of crystals within the corneal stroma which cause corneal ...
Kyrle disease
... posterior subcapsular cataracts and two of those three developed multiple tiny yellow-brown anterior stromal corneal opacities ...
Riboflavin
Other signs include corneal opacity, lenticular cataracts, hemorrhagic adrenals, fatty degeneration of the kidney and liver, ... Corneal ectasia is a progressive thinning of the cornea; the most common form of this condition is keratoconus. Collagen cross- ... applying riboflavin topically then shining UV light is a method to slow progression of corneal ectasia by strengthening corneal ...
Confocal microscopy
The SLM is a device containing an array of pixels with some property (opacity, reflectivity or optical rotation) of the ... It is used for localizing and identifying the presence of filamentary fungal elements in the corneal stroma in cases of ...
Amelogenesis imperfecta
X-ray showing lack of enamel opacity and a pathological loss of enamel in patient with amelogenesis imperfecta ... X-linked endothelial corneal dystrophy. Neuromuscular. *Becker's muscular dystrophy/Duchenne. *Centronuclear myopathy (MTM1) ...
Keratoconjunctivitis
Corneal opacity. *Corneal neovascularization. *Kayser-Fleischer ring. *Haab's striae. *Arcus senilis. *Band keratopathy ...
Medical ultrasound
It is commonly used to see inside the eye when media is hazy due to cataract or any corneal opacity. ...
అంధత్వం - వికీపీడియా
Corneal opacity) (5.1%),. *మధుమేహం (Diabetic retinopathy) (4.8%), ఇతర కారణాలు.. అభివృద్ధి చెందుతున్న దేశాలలో అంధత్వానికి ...
Pagkabulag, ang malayang ensiklopedya
corneal opacity (5.1%), at. *diabetic retinopathy (4.8%),. *pagkabulag sa bata (3.9%),. *trachoma (3.6%) ...
List of diseases (H)
... hyperplasia strabismus Hemifacial microsomia Hemihypertrophy in context of NF Hemihypertrophy intestinal web corneal opacity ...
Category:Ophthalmology
Corneal opacity. *Corneal topography. *Corrective lens. *Cover test. *Cup-to-disc ratio ...
Floater
Laser vitreolysis is a possible treatment option for the removal of vitreous strands and opacities (floaters). In this ... Corneal ectasia *Keratoconus. *Pellucid marginal degeneration. *Keratoglobus. *Terrien's marginal degeneration. *Post-LASIK ... applies a series of nanosecond pulses of low-energy laser light to evaporate the vitreous opacities and to sever the vitreous ...
FOXE3
... the absence of Descemet's membrane and the corneal endothelium, and corneal opacities. This syndrome can be attributed to fetal ... anomaly is a rare disorder obtained during development characterized by adhesions due to malformations of the posterior corneal ...
List of diseases (C)
Cleft lip palate ectrodactyly Cleft lip palate incisor and finger anomalies Cleft lip palate mental retardation corneal opacity ... Corneal anesthesia deafness mental retardation Corneal cerebellar syndrome Corneal crystals myopathy neuropathy Corneal ... recessive Cutis laxa corneal clouding mental retardation Cutis laxa osteoporosis Cutis laxa with joint laxity and retarded ... dystrophy Corneal endothelium dystrophy Cornelia de Lange syndrome Corneodermatoosseous syndrome Coronal synostosis syndactyly ...
X-linked ichthyosis
Atrial fibrillation or atrial flutter may affect up to 1 in 10 males with XLI Corneal opacities may be present but do not ...
List of OMIM disorder codes
VSX1 Corneal dystrophy, lattice type I; 122200; TGFBI Corneal dystrophy, lattice type IIIA; 608471; TGFBI Corneal dystrophy, ... with sutural opacities; 600881; CRYBA1 Cataract, congenital; 604219; BFSP2 Cataract, congenital, cerulean type, 3; 608983; ... ZEB1 Corneal dystrophy, gelatinous drop-like; 204870; TACSTD2 Corneal dystrophy, Groenouw type I; 121900; TGFBI Corneal ... TGFBI Corneal dystrophy, Thiel-Behnke type; 602082; TGFBI Corneal endothelial dystrophy 2; 217700; SLC4A11 Corneal endothelial ...
Fleck corneal dystrophy
Small opacities, some of which resemble "flecks", are scattered in the stroma of the patients. Other opacities look more like ... Fleck corneal dystrophy, also known as Francois-Neetens speckled corneal dystrophy, is a rare form of corneal dystrophy. It is ... Klintworth GK (2009). "Corneal dystrophies". Orphanet J Rare Dis. 4: 7. doi:10.1186/1750-1172-4-7. PMC 2695576. PMID 19236704 ... In a single case report, a corneal transplantation was performed for concurrent keratoconus, and at 10 years follow-up there ...
Testing cosmetics on animals
... body parts and organs taken from animals slaughtered for the meat industry to perform tests such as the Bovine Corneal Opacity ...
WDR37
These include Corneal opacity/Peters anomaly Coloboma Microcornea Cerebellar hypoplasia Epilepsy Dysmorphic facial features ...
Schnyder crystalline corneal dystrophy
Cells in the cornea accumulate cholesterol and phosopholipid deposits leading to the opacity, in severe cases requiring corneal ... Schnyder crystalline corneal dystrophy (SCD) is a rare form of corneal dystrophy. It is caused by heterozygous mutations in ...
Cataract
Corneal incision - Two cuts are made at the margin of the clear cornea to allow insertion of instruments into the eye. ... People with schizophrenia often have risk factors for lens opacities (such as diabetes, hypertension, and poor nutrition) but ... Corneal edema and cystoid macular edema are less serious but more common, and occur because of persistent swelling at the front ... The final step is to inject salt water into the corneal wounds to cause the area to swell and seal the incision. A Cochrane ...
Corneal opacity - Wikipedia
The word Corneal blindness is commonly used to describe blindness due to corneal opacity. Depending on the density, corneal ... Dense corneal opacities may occur in trisomy 8 mosaicism. Farbers disease: Nodular corneal opacity may be seen in association ... Ocular form of mucous membrane pemphigoid may cause corneal opacity and loss of vision. Pediatric corneal opacities may be ... A nebular corneal opacity allows the details of the iris to be seen through the opacity. A thin, diffuse nebula covering the ...
corneal opacity Mammalian Phenotype Term (MP:0001314)
The Mammalian Phenotype (MP) Ontology is a community effort to provide standard terms for annotating phenotypic data. You can use this browser to view terms, definitions, and term relationships in a hierarchical display. Links to summary annotated phenotype data at MGI are provided in Term Detail reports.
Phacoemulsification in Corneal Opacities - American Academy of Ophthalmology
Corneal Opacity - UVA Health System
Corneal opacity occurs when the cornea becomes scarred. This stops light from passing through the cornea to the retina and may ... Corneal opacity is a disorder of the cornea. The cornea is the transparent structure on the front of the eyeball. ... Corneal opacity is a disorder of the cornea. The cornea is the transparent structure on the front of the eyeball. Corneal ... To help reduce your chance of corneal opacity:. *Take care to avoid injuring the eye. Wear eye protection during any ...
Congenital Corneal Opacities - Sub Saharan Africa - American Academy of Ophthalmology
The prevalence of congenital corneal opacities (CCO) is estimated to be 3 in100,000 newborns. This number increases to 6 in ... Chart 2. Management of of congenital corneal opacities.. Global Information. *Treatment of congenital corneal opacities is ... Table 2. Differential Diagnosis of Infantile Corneal Opacities. Entity. Location and Description of Opacity. Other Signs. ... Central opacity; unilateral. Breaks in Descemet membrane. History. Posterior corneal defect. Central opacity; unilateral or ...
Corneal Opacity | Sky Ridge Medical Center
Learn more about Corneal Opacity at Sky Ridge Medical Center DefinitionCausesRisk ... Corneal opacity is a disorder of the cornea. The cornea is the transparent structure on the front of the eyeball. Corneal ... To help reduce your chance of corneal opacity:. *Take care to avoid injuring the eye. Wear eye protection during any ... Infection, injury, or swelling of the eye are the most common causes of corneal opacity. ...
Overview | Implantation of a corneal graft-keratoprosthesis for severe corneal opacity in wet blinking eyes | Guidance | NICE
Evidence-based recommendations on implantation of a corneal graft-keratoprosthesis for severe corneal opacity in wet blinking ... Implantation of a corneal graft-keratoprosthesis for severe corneal opacity in wet blinking eyes. Interventional procedures ... implantation of a corneal graft-keratoprosthesis for severe corneal opacity in wet blinking eyes in November 2015. ... H17.- Corneal scars and opacities would be recorded.. The Clinical Classifications Service has advised NICE that currently ...
Corneal Opacity | Reston Hospital Center
Learn more about Corneal Opacity at Reston Hospital Center DefinitionCausesRisk ... Corneal opacity is a disorder of the cornea. The cornea is the transparent structure on the front of the eyeball. Corneal ... Corneal opacity. The Fred Hollows Foundation NZ website. Available at: http://www.hollows.org.nz/content/corneal-opacity. ... To help reduce your chance of corneal opacity:. *Take care to avoid injuring the eye. Wear eye protection during any ...
Alternative treatments for corneal opacity - Doctor answers
Cremers on alternative treatments for corneal opacity: First, it is best to try to identify and treat the underlying disease ... Keratoconus: Corneal transplant is a highly successful surgery in keratoconus patients in which all other treatment options ... It is better to consult a corneal specialist for exam and advice. You may need laser or graft. ...Read more ... Fuchs: It depends on a multitude of factors such as your best corrected vision, your corneal thickness, your endothelial cell ...
Induced corneal opacities in the rat. | British Journal of Ophthalmology
Slit beam enhances visualization with corneal opacities | OphthalmologyTimes
... can also be used to enhance visualization during cataract surgery in patients who have corneal opacities. ... "I found that when I examined patients with corneal opacities and cataracts with the slit beam I could see details inside the ... Rateb noted that about 20% of his patients have severe corneal opacities associated with the high prevalence of trachoma in ... Slit beam enhances visualization with corneal opacities Use on operating microscope affords detailed view of ocular structures ...
Trypan blue assisted phacoemulsification in corneal opacities | British Journal of Ophthalmology
Most patients had corneal opacity due to healed keratitis (Table 1). Two eyes had undergone previous corneal surgery in the ... These may include situations such as asteroid hyalosis, corneal scarring, corneal oedema, or a dark brunescent nucleus. Corneal ... corneal opacities. Trypan blue is used to stain the capsule for better visibility during capsulorhexis in white cataracts.1,2 ... Patients with nebulomacular corneal opacities and a visually debilitating cataract may become ambulatory with cataract surgery ...
ICD-9-CM Diagnosis Codes 371.* : Corneal opacity and other disorders of cornea
371.00 Corneal opacity, unspecified convert 371.00 to ICD-10-CM. *. 371.01 Minor opacity of cornea convert 371.01 to ICD-10-CM ... 371.02 Peripheral opacity of cornea convert 371.02 to ICD-10-CM. *. 371.03 Central opacity of cornea convert 371.03 to ICD-10- ... 371.53 Granular corneal dystrophy convert 371.53 to ICD-10-CM. *. 371.54 Lattice corneal dystrophy convert 371.54 to ICD-10-CM ... 371.81 Corneal anesthesia and hypoesthesia convert 371.81 to ICD-10-CM. *. 371.82 Corneal disorder due to contact lens convert ...
Bovine Corneal Opacity and Permeability (BCOP) | Bioscience Labs
The Bovine Corneal Opacity and Permeability (BCOP) test is an In-Vitro method to evaluate chemicals inducing serious eye damage ... Bovine Corneal Opacity and Permeability (BCOP). The Bovine Corneal Opacity and Permeability (BCOP) test is an in-vitro method ... The Bovine Corneal Opacity and Permeability (BCOP) test method is an in-vitro test method that can be used, under certain ... Bovine Corneal Opacity and Permeability (BCOP) Test Method for Identifying Ocular Corrosives/Severe Irritants and Substances ...
Corneal opacity | definition of corneal opacity by Medical dictionary
... corneal opacity explanation free. What is corneal opacity? Meaning of corneal opacity medical term. What does corneal opacity ... Looking for online definition of corneal opacity in the Medical Dictionary? ... Corneal opacity , definition of corneal opacity by Medical dictionary https://medical-dictionary.thefreedictionary.com/corneal+ ... A dense, white corneal opacity. Causes include untreated syphilis, corneal inflammation or ulceration, and trachoma. Called ...
2021 ICD-10-CM Diagnosis Code H17.9: Unspecified corneal scar and opacity
Differential Diagnosis of Corneal Opacities - Optometry Australia
Differential Diagnosis of Corneal Opacities. Independent Learning with Assessment. Yes. No. 2.00. ... To revisit corneal anatomy and function to improve the understanding of the pathophysiology of corneal disease ... To understand the new ICD3 classification of corneal dystrophies (edition 2) and practice implementing these classifications ... To work through a decision matrix in order to better differentially diagnose corneal pathology ...
Frontal bossing and Corneal opacity, related diseases and genetic alterations | MENDELIAN.CO
Homozygous mutations in PXDN cause congenital cataract, corneal opacity, and developmental glaucoma | Hereditary Ocular Diseases
Corneal Opacity & Palmar Hyperlinearity<...
Corneal Opacity & Palmar Hyperlinearity Symptom Checker: Possible causes include Ichthyosis Vulgaris & Atopic Cataract & X- ... Characteristic corneal opacities are small punctate or filiform lesions and are located in the deep corneal stroma.[ncbi.nlm. ... Platanus occidentalis is prescribed for X linked ichthyosis with corneal opacity and cataract .[ks-gopi.blogspot.com] opacities ... The disorder occurs only in males.[symptoma.com] There may be associated corneal opacities that do not affect vision.[ncbi.nlm. ...
Quiz: Central Corneal Opacities | Cybersight
corneal opacity treatment
Corneal Opacity - SlideShare. Slideshare.net. 8. Depending upon the density, corneal opacity is graded as: Nebular: faint ... Evaluation and Management of Corneal Abrasions - American .... Aafp.org. A corneal opacity or infiltrate may occur with corneal ... Corneal Opacities: Eye Disorders That Can Cause Vision Loss. Webmd.com. Minor corneal abrasions heal quickly, usually within ... This type of corneal opacity may be exogenous, resulting from a lime burn, or may be endogenous in the band keratopathies ...
Drushti|Eye and Retina Center:-Corneal Opacity With Detachment
Imitrex Nasal Spray (Sumatriptan Nasal Spray): Uses, Dosage, Side Effects, Interactions, Warning
Corneal Opacities: Dogs receiving oral sumatriptan developed corneal opacities and defects in the corneal epithelium. Corneal ... Corneal Opacities. Sumatriptan causes corneal opacities and defects in the corneal epithelium in dogs; this raises the ... Defects in the corneal epithelium were noted in a 60-week study. Earlier examinations for these toxicities were not conducted ... There is evidence of alterations in corneal appearance on the first day of intranasal dosing to dogs. Changes were noted at the ...
Axert (Almotriptan Malate): Side Effects, Interactions, Warning, Dosage & Uses
Corneal Opacities. Three male dogs (out of a total of 14 treated) in a 52-week toxicity study of oral almotriptan developed ... slight corneal opacities that were noted after 51 weeks, but not after 25 weeks of treatment. The doses at which this occurred ... The opacity reversed after a 4-week drug-free period in the affected dog treated with the highest dose. Systemic exposure ( ...
The RodA Hydrophobin on Aspergillus fumigatus Spores Masks Dectin-1- and Dectin-2-Dependent Responses and Enhances Fungal...
5 × 104 live G10 and ΔrodA conidia were injected into the corneal stroma of C57BL/6 mice, and corneal opacity, neutrophil ... ΔrodA mutant exhibited significantly higher percent and total corneal opacity at 24 h, but had significantly lower corneal ... Imaging corneal opacity. Mice were sacrificed by CO2 asphyxiation and positioned in a three-point stereotactic mouse restrainer ... C57BL/6, Dectin-1−/−, and Dectin-2−/− mice were infected intrastromally with ΔrodA or G10 conidia, and CFU, corneal opacity, ...
DailyMed - CLARAVIS- isotretinoin capsule, liquid filled
corneal opacities (see WARNINGS, Corneal Opacities), decreased night vision which may persist (see WARNINGS, Decreased Night ... Corneal Opacities. Corneal opacities have occurred in patients receiving Claravis for acne and more frequently when higher drug ... The corneal opacities that have been observed in clinical trial patients treated with Claravis have either completely resolved ...
ACCUTANE®(isotretinoin capsules)
corneal opacities (see WARNINGS: Corneal Opacities), decreased night vision which may persist (see WARNINGS: Decreased Night ... Corneal Opacities Corneal opacities have occurred in patients receiving Accutane for acne and more frequently when higher drug ... The corneal opacities that have been observed in clinical trial patients treated with Accutane have either completely resolved ...
Amblyopia and Strabismus by Monocular Corneal Opacity Following Suspected Epidemic Keratoconjunctivitis in Infancy | Korean...
Each developed a monocular corneal opacity. Three patients with a chief complaint of corneal opacity were transferred to our ... To identify the long term clinical course of amblyopia and strabismus that developed secondary to a monocular corneal opacity ... Amblyopia and Strabismus by Monocular Corneal Opacity Following Suspected Epidemic Keratoc Amblyopia and Strabismus by ... Adenoviridae Infections/complications , Amblyopia/etiology , Child , Child, Preschool , Corneal Opacity/complications , Disease ...
The Development of Corneal Opacity, Increased Hydration and Increased Thickness in Isolated Porcine Corneas in Response to...
Temp Worker 2017-01-09T06:25:58+00:00 Tags: !imolol maleate, benzalkonium chloride, corneal hydration, corneal opacity, corneal ... Home/ATLA 24, 1996/ATLA 24.1, January 1996/The Development of Corneal Opacity, Increased Hydration and Increased Thickness in ... The Development of Corneal Opacity, Increased Hydration and Increased Thickness in Isolated Porcine Corneas in Response to ... The Development of Corneal Opacity, Increased Hydration and Increased Thickness in Isolated Porcine Corneas in Response to ...
CorneaStromaOpacificationTransplantationDystrophyDystrophiesVisual acuityScarsCongenital corneal opacityGlaucomaBlindnessCentral corneal opacitiesUlcerEpithelialEdemaKeratoplastyBovine Corneal OpacityThicknessKERATITISBilateral cornealMembraneIntraocularUlcerationTreatments for cornealConjunctivitisNeovascularizationDiagnosisHazeSevereOphthalmologyKeratopathyInflammationLamellaeDevelopmentalTransplantInfiltrationDenseMethodsPatientsPhototherapeutic keratectomySymptomsCorneasClinical
Cornea29
- The word corneal opacification literally means loss of normal transparency of cornea. (wikipedia.org)
- The term corneal opacity is used particularly for the loss of transparency of cornea due to scarring. (wikipedia.org)
- It is a dense white opacity which results due to scarring of more than half of the stroma Adherent leucoma: It results when healing occurs after perforation of cornea with incarceration of iris. (wikipedia.org)
- The appearance of the cornea is similar to that in congenital glaucoma but without increased corneal diameter and elevated intraocular pressure. (wikipedia.org)
- Congenital hereditary stromal dystrophy (CHSD): CHSD is also known as Congenital stromal corneal dystrophy or Congenital stromal dystrophy of the cornea. (wikipedia.org)
- In this bilateral Snowflake, whitish opacities appear throughout the cornea. (wikipedia.org)
- Corneal opacity is a disorder of the cornea. (uvahealth.com)
- Corneal opacity occurs when the cornea becomes scarred. (uvahealth.com)
- Some retrospective studies have shown Peters anomaly to be the most common congenital corneal opacity presenting to a university cornea clinic. (aao.org)
- Facts about the cornea and corneal disease. (skyridgemedcenter.com)
- Eleven eyes of 11 patients with cataract and nebulomacular corneal opacities due to various aetiologies (Table 1) were recruited prospectively from the cornea service of the Dr Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi, a tertiary eye care referral centre. (bmj.com)
- The neovascularization is usually benign and appears as a superior corneal pannus with superficial vessels extending 1-2 mm into the cornea. (keyword-suggest-tool.com)
- Corneal pachymetry - an ultrasound which measures the thickness of the cornea and is important in assigning risk to patients with ocular hypertension and glaucoma. (healthpoint.co.nz)
- The aim of this project is to develop methods for imaging the cornea with an FD-OCT system that will precisely measure corneal shape and use this information to guide surgery. (clinicaltrials.gov)
- All the patients selected for the study had a central corneal opacity and at least one quadrant of clear peripheral cornea. (beds.ac.uk)
- This evaluation included uncorrected visual acuity, best corrected visual acuity (BCVA), best visual acuity after dilatation and, using a stenopic slit, slit lamp biomicroscopy of the anterior segment to look for the size and depth of the corneal opacity, the quadrant of clear cornea and the amount of cataract after dilatation of pupil. (beds.ac.uk)
- Corneal opacity is a disorder of the cornea, the transparent covering of the eyeball, which can cause serious vision problems. (knowyourdisease.com)
- The OECD Test Guideline 437 Bovine Corneal Opacity and Permeability (BCOP) test method allows determining severely irritating substances without animals, and the recently adopted OECD Test Guideline 492 Reconstructed human cornea-like epithelium test method allows identifying chemicals that neither induce eye irritation nor serious eye damage. (biomedcentral.com)
- Eiben R. Frequency of spontaneous opacities in the cornea and lens observed in chronic toxicity studies in Wistar rats: experience with a standardized terminology glossary (Hattersheimer Kreis). (springer.com)
- Corneal dystrophy or corneal opacities are white or silver spots on the central area of the cornea. (dogster.com)
- Corneal scars extending beyond the anterior one-fifth of the cornea can be treated safely and effectively by PTK due to the smoothing effect, with reduction of the cylinder rather than complete opacity removal. (dovepress.com)
- Don't forget to test for corneal sensation (a rolled cotton bud lightly touching the cornea ) and then re-examine the cornea using fluorescein. (tripdatabase.com)
- CONCLUSION: The oil red O positive deposits and their variation in density in the subepithelial area of the cornea may have caused the characteristic whorl-like corneal opacity in this woman who was heterozygous for Fabry's disease. (biomedsearch.com)
- This is a viral disease that causes nervous symptoms, reproductive failure and opacity or blueing of the cornea. (thepigsite.com)
- We are also developing intraocular electronic display prostheses for bypassing cornea opacity, a novel strategy that could allow for high quality vision without corneal clarity. (stanford.edu)
- Corneal defects and neovascularization were induced in vivo by infliction of an alkali burn to the cornea with 1 N sodium hydroxide solution in RAP1 knock-out (RKO) and wild-type (RWT) mice. (arvojournals.org)
- Resurfacing of the burned cornea was accelerated and angiogenesis was suppressed, faster recovery of corneal epithelial cells from classic scratch wound healing and superior tolerance of lipopolysaccharides challenge was observed in the RKO compared to RWT. (arvojournals.org)
- congenital opacity of the cornea occurs in cattle. (thefreedictionary.com)
- The corneal reflex can be elicited in a normal animal by gently touching the cornea with a wisp of cotton. (thefreedictionary.com)
Stroma14
- It is a faint opacity which results due to superficial scars involving Bowman's layer and superficial stroma. (wikipedia.org)
- It is a semi-dense opacity produced when scarring involves about half the corneal stroma. (wikipedia.org)
- The proband (ǁǀ5) is a 9 year-old boy with generalized dry and grey brown scales, without involvement of the palms, soles and face, and no palmar hyperlinearity , accompanied [ijdvl.com] Characteristic corneal opacities are small punctate or filiform lesions and are located in the deep corneal stroma. (symptoma.com)
- Treatment with a solution of this material is appropriate for corneal opacities which consist of calcific deposits in the anterior layers of the stroma or in the epithelium. (keyword-suggest-tool.com)
- 8. Depending upon the density, corneal opacity is graded as: Nebular: faint opacity due to superficial scar involving bowman's layer and superficial stroma. (keyword-suggest-tool.com)
- 9. Macular: Semi dense opacity d/t scar involving half of stroma. (keyword-suggest-tool.com)
- 10. Leucomatous: Dense white opacity d/t scarring of more than half of stroma. (keyword-suggest-tool.com)
- Using a murine model of Aspergillus corneal infection, we also demonstrate that in the absence of RodA, A. fumigatus induces Dectin-1- and Dectin-2-dependent neutrophil recruitment to the corneal stroma and enhanced fungal killing. (jimmunol.org)
- The surgeon uses the OCT data to plan a range of treatment parameters to remove most of the opacity while preserving at least 250 microns of residual corneal stroma. (clinicaltrials.gov)
- In high-risk corneal transplantation, where the graft bed is inflamed and vascularized, immature APCs in the donor corneal stroma quickly mature and migrate to lymphoid tissues to sensitize host T cells. (nature.com)
- We have previously shown that resident bone marrow-derived CD11b + and CD11c + cells in the central corneal stroma stay in a highly immature state under normal conditions, expressing very low levels of MHC-II and co-stimulatory molecules. (nature.com)
- Such chemicals penetrate tissue more rapidly than acids to reach the corneal stroma and destroy tissues with a consequent severe inflammatory response. (arvojournals.org)
- occurs when fluid accumulates in the corneal stroma, disrupting the normal lamellar structure and causing a loss of transparency. (thefreedictionary.com)
- The melanin is in the superficial stroma and the basal layer of the corneal epithelium. (thefreedictionary.com)
Opacification6
- Bilateral corneal neovascularization and opacification associated with unmonitored contact lens wear. (restonhospital.com)
- Assiut, Egypt- A slit beam mounted on a surgical microscope can enhance visualization during cataract surgery, particularly in patients with corneal opacification, according to Mahmoud F. Rateb, MD. (modernmedicine.com)
- Trypan blue assisted phacoemulsification may be performed in selected cases of corneal haze/opacification with cataract. (bmj.com)
- We had been performing routine extracapsular cataract extraction and a 6.5 mm optic poly(methylmethacrylate) (PMMA) intraocular lens implantation in those cases of cataract with corneal opacification where it was not possible to clearly visualise the anterior capsule to be able to perform a capsulorhexis. (bmj.com)
- Inclusion criteria consisted of the presence of corneal opacification involving the visual axis partially, along with the presence of visually debilitating cataract. (bmj.com)
- Here, we report homozygous mutations in peroxidasin (PXDN) in two consanguineous Pakistani families with congenital cataract-microcornea with mild to moderate corneal opacity and in a consanguineous Cambodian family with developmental glaucoma and severe corneal opacification. (edu.au)
Transplantation10
- Lasik surgery is relatively safe and effective surgery , if you are undergoing such surgery you have to take time , find pros and cons of such procedure and go to the best centers not to the mills, ask the surgeon for possible complications not simple flares , refractive errors , but requiting corneal transplantation , flap problems , infection etc these are rare but can happen. (healthtap.com)
- 3 Furthermore, trypan blue is routinely used to examine the endothelial cell layer of donor corneoscleral buttons before corneal transplantation. (bmj.com)
- Diagnosis and corneal transplantation. (bookinghealth.com)
- In addition to the conventional surgery, here are performed all forms of lamellar corneal transplantation. (bookinghealth.com)
- The Department of Ophthalmology enjoys an international reputation in the field of its specialization - corneal transplantation. (bookinghealth.com)
- The Department has 10 years of experience in the field of corneal transplantation. (bookinghealth.com)
- Although corneal transplantation with cataract extraction and intraocular lens implantation is the preferred method for treating corneal scars with a cataract, the scarcity of donor material and the risk of graft failure, particularly in high-risk keratoplasty, create the need for other methods for improving vision. (beds.ac.uk)
- In this study, using a mouse model of corneal transplantation, we investigated whether enrichment of tolerogenic APCs (tolAPCs) in donor corneas can enhance graft survival in corneal allograft recipients with inflamed graft beds. (nature.com)
- Transplantation of these tolAPC-enriched corneas decreased frequencies of interferon gamma (IFNγ) + effector T cells (Teffs), as well as allosensitization in the hosts, diminished graft infiltration of CD45 + and CD4 + cells, and significantly improved corneal allograft survival compared to saline-injected controls. (nature.com)
- Successful long-term survival of grafts without evidence of xenozoonosis in clinically applicable pig-to-non-human primate corneal transplantation model has brought researchers close to human clinical trials. (elsevier.com)
Dystrophy9
- Alterations in the spacing of collagen fibrils in a variety of conditions including corneal edema, scars, and macular corneal dystrophy is clinically manifested as corneal opacity. (wikipedia.org)
- Posterior Polymorphous Corneal Dystrophy (PPMD, PPCD): PPCD, also known as Schlichting dystrophy, is an autosomal dominant disorder of the corneal endothelium and Descemet's membrane. (wikipedia.org)
- Best treatment for corneal edema/fuch's dystrophy? (healthtap.com)
- PURPOSE:To report results of femtosecond laser-assisted lamellar keratectomy (FLK) for corneal opacities secondary to anterior corneal dystrophies.METHODS:Patients with a clinical diagnosis of Reis-Bücklers corneal dystrophy, granular corneal dystrophy, lattice corneal dystrophy, and macular corneal dystrophy were treated. (ulster.ac.uk)
- Patients with stromal corneal dystrophies had worse outcome than those with Reis-Bücklers corneal dystrophy.CONCLUSIONS:In this case series, FLK provided both therapeutic and diagnostic intervention, delaying more invasive surgery. (ulster.ac.uk)
- These mice exhibit corneal opacity, poor wound healing, are hyporesponsive to LPS-induced sepsis and may be useful in studies of corneal dystrophy, extracellular matrix and neutrophil migration during the immune response. (jax.org)
- Looking for information on Dog Corneal Dystrophy (Corneal Opacities) in Sioux Falls? (dogster.com)
- We hope this page helps you find information on Dog Corneal Dystrophy (Corneal Opacities) in Sioux Falls. (dogster.com)
- Whats fuchs's corneal dystrophy? (healthtap.com)
Dystrophies2
- Eyes with superficial opacities (corneal scars and stromal dystrophies) can be treated by phototherapeutic keratectomy (PTK). (clinicaltrials.gov)
- Some dystrophies can be readily treated by CORNEAL GRAFT . (thefreedictionary.com)
Visual acuity4
- A cataract is often associated with corneal opacity and contributes to the poor visual acuity. (beds.ac.uk)
- Preoperative and postoperative refraction, best spectacle-corrected visual acuity, corneal topography results, and color photographs were recorded. (ulster.ac.uk)
- Changes in uncorrected visual acuity and best spectacle-corrected visual acuity, keratometry, refractive error, corneal irregularity, residual or recurrent central corneal opacities, and corneal haze were used to assess the outcome.RESULTS:Eight eyes of 6 patients were treated. (ulster.ac.uk)
- Results: Two patients with bilateral legal corneal blindness (best-corrected visual acuity ≤20/200 in the better eye and ≤20/1000 in the candidate eye) or with (impending) corneal perforation will be enrolled. (elsevier.com)
Scars3
- Corneal scars and opacities would be recorded. (nice.org.uk)
- In addition the ICD-10 code H17.Corneal scars and opacities would be recorded. (nice.org.uk)
- The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures. (clinicaltrials.gov)
Congenital corneal opacity2
- Signs and symptoms include the following: Loss of vision or Blindness (when dense opacity covers the pupillary area) Blurred vision (due to astigmatic effect and light scattering) Glare Congenital corneal opacity that affecting vision will cause amblyopia. (wikipedia.org)
- Spontaneous regression of congenital corneal opacity. (nih.gov)
Glaucoma1
- One of the major complication of adherent leucoma is Secondary glaucoma Corneoiridic scar: If iris tissue is incarcerated and incorporated within the scar tissue, as occurs in healing of a large sloughed corneal ulcer, it is called a corneoiridic scar. (wikipedia.org)
Blindness7
- The word 'Corneal blindness' is commonly used to describe blindness due to corneal opacity. (wikipedia.org)
- A study of congenital eye disease at a teaching hospital in Sagamu, Nigeria, found that corneal opacities is the fourth most common congenital eye disorder causing blindness in 5.7% of infants with congenital eye diseases (Bodunde et al, 2006). (aao.org)
- As Aspergillus and Fusarium species are also major causes of corneal infection and blindness worldwide ( 6 ), the current study examined the role of hydrophobins in a murine model of fungal keratitis ( 7 , 8 ). (jimmunol.org)
- Corneal opacity is an important cause of blindness, especially in third world countries. (beds.ac.uk)
- resultant scarring can lead to corneal opacity and blindness. (britannica.com)
- Corneal opacity is a leading cause of blindness. (stanford.edu)
- Our laboratory is developing multiple strategies for treatment of corneal blindness. (stanford.edu)
Central corneal opacities1
- left) central corneal opacities with central irido-corneal adhesions on the right and mild microcornea. (cybersight.org.cn)
Ulcer4
- Four patients in our clinic underwent a corneal ulcer treatment following suspected EKC. (bvsalud.org)
- Bacterial keratitis or corneal ulcer is due to micro-trauma usually from contact lens use (over wear). (healthtap.com)
- What is bacterial keratitis (corneal ulcer)? (healthtap.com)
- It is a corneal ulcer caused by waterborne amoeba, often found in lakes and canals in tropical areas. (healthtap.com)
Epithelial3
- A second goal is to develop a more sophisticated OCT guidance system incorporating OCT topography of anterior and posterior corneal surfaces and to develop a mathematical model that relates epithelial thickness variation to corneal mean curvature. (clinicaltrials.gov)
- Corneal epithelial cells were isolated for classic scratch wound healing assay and further testing with lipopolysaccharide stimulation. (arvojournals.org)
- 1 , 2 Nuclear factor kappa light chain enhancer of activated B cells (NFκB) signaling family factors have been implicated in the regulation of inflammation 3 and angiogenesis 4 - 6 in many cell types, including corneal epithelial cells. (arvojournals.org)
Edema4
- With long period use in high dose , tamoxifen can cause ocular side effects such as retinal crystalline deposition, macular edema , whorl-like corneal opacities , posterior subcapsular lens opacities , optic neuritis , and affected EOG . (bvsalud.org)
- Specifically, Category 2 is assigned if a substance produces - at least in 2 of 3 tested animals - a positive response of corneal opacity ≥1 and/or iritis ≥1 and/or conjunctival redness ≥2 and/or conjunctival edema (chemosis) ≥2 (calculated as the mean scores following grading at 24, 48 and 72 h after treatment) and all effects are fully reversible within 21 days [ 5 ]. (biomedcentral.com)
- May cause corneal edema and ulceration. (thefreedictionary.com)
- The lesion is an edema of the corneal lamellae. (thefreedictionary.com)
Keratoplasty6
- PPMD patients with bilateral, corneal opacities that can affect vision, descemet's membrane endothelial keratoplasty or penetrating keratoplasty are the treatments of choice to improve vision and to avoid amblyopia. (wikipedia.org)
- These patients may be simultaneously placed on waiting lists for both cataract surgery and keratoplasty but may not be scheduled for the corneal transplant for years. (modernmedicine.com)
- Keratoplasty was needed in many cases where corneal opacity hindered the vision but due to lack of keratoplasty facilities in our hospital patients were referred to other hospitals where keratoplasty facilities were available and hence most of them were lost to follow-up. (thefreedictionary.com)
- Prior to surgery the patients were informed of the prognosis and the advantages and disadvantages of the surgery over a corneal triple procedure (penetrating keratoplasty in combination with extracapsular cataract extraction and intraocular lens implantation). (beds.ac.uk)
- Eight eyes required concomitant penetrating or lamellar keratoplasty because of corneal opacity. (nih.gov)
- This study aimed to evaluate the effectiveness of phototherapeutic keratectomy (PTK) as an alternative treatment to keratoplasty using the Pentacam to assess depth of dense opacities. (dovepress.com)
Bovine Corneal Opacity3
- The Bovine Corneal Opacity and Permeability (BCOP) test is an in-vitro method to evaluate chemicals inducing serious eye damage or serious eye irritation. (biosciencelabs.com)
- Interlaboratory assessment of the bovine corneal opacity and permeability (BCOP) assay. (thefreedictionary.com)
- With the adoption of the TG for the Bovine Corneal Opacity and Permeability (BCOP) test method for identifying ocular corrosives and severe irritants (OECD TG 437) in 2009, it became possible to register severely irritating substances (i.e. (biomedcentral.com)
Thickness2
- It depends on a multitude of factors such as your best corrected vision , your corneal thickness, your endothelial cell count (health of the inner layer of cells). (healthtap.com)
- PTK was performed in eleven eyes of ten patients with superficial corneal opacities after assessment by Scheimpflug images of the Pentacam for central corneal thickness (CCT) and opacity level and depth. (dovepress.com)
KERATITIS1
- Called also focal superficial necrosis, corneal mummification, keratitis nigrum. (thefreedictionary.com)
Bilateral corneal2
- A baby with clinical findings of a large head, short stature , low set ears, short and curved limbs, small thorax, bilateral corneal opacities and radiographs showing short and curved long bones, femurs like telephone- receiver look, H- shaped vertebrae, small iliac wings was reported. (adpublications.org)
- So when a case of Thanatophoric dysplasia Type 1 with bilateral corneal opacities was attended at pediatric department, a detailed report was prepared to publish such a rare case. (adpublications.org)
Membrane6
- Ocular trauma Corneal ulceration Xerophthalmia, caused by Vitamin A deficiency Trachoma Onchocerciasis Mucous membrane pemphigoid: Ocular form of mucous membrane pemphigoid may cause corneal opacity and loss of vision. (wikipedia.org)
- To determine whether preserved human amniotic membrane can reduce corneal haze and keratocyte apoptosis induced by excimer laser photoablation in rabbit corneas. (nih.gov)
- A consistent grading of differences in corneal haze scoring between the control corneas and the amniotic-membrane-covered corneas was noted among the 3 masked observers. (nih.gov)
- Amniotic membrane matrix introduced at an early stage of the corneal wound healing process effectively reduced corneal haze induced by excimer laser photoablation in rabbits. (nih.gov)
- Use of human fibrin glue and amniotic membrane transplant in corneal perforation. (biomedsearch.com)
- Additionally, some patient's with Fuchs' get a plaque or membrane in their central corneal causing vision decline. (healthtap.com)
Intraocular3
- 11 eyes of 11 patients with nebulomacular corneal opacities involving the visual axis with partially and visually debilitating cataract underwent trypan blue assisted phacoemulsification with foldable intraocular lens implantation. (bmj.com)
- We found a statistically significant correlation between minor criteria of AD like palmar hyperlinearity and combination of xerosis and Dennie-Morgan fold and the presence [ijdvl.com] In addition, measurement of intraocular pressures and corneal diameters are performed. (symptoma.com)
- Extracapsular cataract extraction and intraocular lens implantation with pupillary sphincterotomy provides ambulatory and useful vision to patients of cataract with coexisting central leucomatous corneal opacity. (beds.ac.uk)
Ulceration1
- Causes include untreated syphilis, corneal inflammation or ulceration, and trachoma. (thefreedictionary.com)
Treatments for corneal1
- Successful treatments for corneal scarring are lacking. (thefreedictionary.com)
Conjunctivitis4
- To rule out other infectious diseases such as bovine herpesvirus type 1 (BHV-1), bovine viral diarrhea virus (BVDV), and toxoplasmosis, which can cause eye problems such as corneal opacity , cataracts (Potgieter, 2004), and conjunctivitis (Weiblen, 1992), the sera of the calf and its dam were tested. (thefreedictionary.com)
- Case-patient 3 was a 45-year-old man from Kuyuwiniña with a 5-year history of TT, madarosis, blepharitis, conjunctivitis, and corneal opacity in both eyes. (cdc.gov)
- Dogs may develop bronchopneumonia, conjunctivitis, photophobia, and a transient corneal opacity, "blue eye", which may occur after clinical recovery as result of anterior uveitis and oedema [ 9 , 10 ]. (hindawi.com)
- Corneal opacity - conjunctivitis. (thepigsite.com)
Neovascularization4
- What are any treatment options for corneal neovascularization with corneal scarring? (healthtap.com)
- After major damage, clear corneal tissue may be replaced by scar tissue or become occluded by new blood vessels (a problem called neovascularization). (keyword-suggest-tool.com)
- The effects of RAP1 deletion on corneal resurfacing and neovascularization in a corneal alkali burn mouse model were examined. (arvojournals.org)
- The cytokine profiles of corneal tissue involved in inflammation and neovascularization following injury was compared between RKO and RWT mice. (arvojournals.org)
Diagnosis3
- Table 2 highlights the differential diagnosis of infantile corneal opacities and the method of diagnosis. (aao.org)
- Differential diagnosis for congenital opacities, Part 1. (aao.org)
- RESULTS: Low levels of alpha-galactosidase in the leukocytes together with the corneal finding led to the diagnosis of heterozygous Fabry's disease. (biomedsearch.com)
Haze3
- Corneal haze can impede adequate visibility even in the presence of an adequate fundus glow. (bmj.com)
- The role of capsular staining for such cases with impaired visualisation due to corneal haze has not been previously described. (bmj.com)
- The amniotic membranes were removed at 1 week, and corneal haze was graded with slitlamp biomicroscopy by 3 masked corneal specialists biweekly for the ensuing 12 weeks until the rabbits were killed. (nih.gov)
Severe4
- The National Institute for Health and Care Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on, implantation of a corneal graft-keratoprosthesis for severe corneal opacity in wet blinking eyes in November 2015. (nice.org.uk)
- Dr. Rateb noted that about 20% of his patients have severe corneal opacities associated with the high prevalence of trachoma in Egypt. (modernmedicine.com)
- The failure of appropriate corneal repair following severe injury (such as chemical burn injuries) often leads to loss of vision. (arvojournals.org)
- Alkali burn is one of the most severe corneal injuries because alkali agents are lipophilic. (arvojournals.org)
Ophthalmology4
- I found that when I examined patients with corneal opacities and cataracts with the slit beam I could see details inside the eye better, such as the anterior capsule, the nucleus, and sometimes other minute details," said Dr. Mahmoud, lecturer and consultant of ophthalmology, Assiut University Hospital, Egypt. (modernmedicine.com)
- The Department of Ophthalmology at the University Hospital Dusseldorf specializes in the treatment of diseases of the anterior eye segment, particularly, in corneal diseases. (bookinghealth.com)
- In close cooperation with other university medical institutions, the Department of Ophthalmology gains annually more than 500 corneal transplants. (bookinghealth.com)
- METHOD: A 67-year-old woman was found to have a whorl-like corneal opacity on her visit to the Department of Ophthalmology. (biomedsearch.com)
Keratopathy1
- We experienced a case of keratopathy of corneal opacity without disorder of retina , lens, and optic nerve in low dose tamoxifen therapy for breast cancer . (bvsalud.org)
Inflammation1
- The roles of RAP1 in regulation of inflammation and angiogenesis for corneal recovery following corneal injury remain poorly understood. (arvojournals.org)
Lamellae1
- When Dr. Rateb began performing cataract surgery under the slit beam, he found that this eliminated the glare from scatter produced by the irregular corneal lamellae characteristic of corneal opacities. (modernmedicine.com)
Developmental1
- Congenital opacities may occur as developmental anomalies or following birth trauma. (wikipedia.org)
Transplant3
- Tips about corneal transplant as treatment for keratoconus? (healthtap.com)
- Corneal transplant is a highly successful surgery in keratoconus patients in which all other treatment options have been exhausted. (healthtap.com)
- In a recent study we have shown that ex vivo treatment of donor-type bone marrow-derived dendritic cells (BMDCs) with immunomodulatory cytokines (IL-10, TGFβ1) renders them tolerogenic, and when systemically transferred to corneal transplant recipients significantly improves allograft survival 19 . (nature.com)
Infiltration4
- Additionally, mice receiving antibody against MIP-2 had decreased corneal opacity and reduced neutrophil infiltration [19]. (thefreedictionary.com)
- Using a murine model of A. fumigatus corneal infection, we showed that Δ rodA conidia induced significantly higher cytokine production, neutrophil infiltration, and more rapid fungal clearance from C57BL/6 corneas compared with the parent G10 strain, which was dependent on Dectin-1 and Dectin-2. (jimmunol.org)
- Failure occurred in two eyes (one each in 9- and 10-year-old boys) that developed corneal infiltration and vascularization. (nih.gov)
- We suspect cardiomyopathy to be due to myocardic infiltration with Gaucher cells, and corneal opacities to result from an accumulation of lipid-like inclusions into the posterior stromal keratinocytes. (ktu.edu.tr)
Dense3
- A dense, white corneal opacity. (thefreedictionary.com)
- Dense, white, corneal opacity caused by scar tissue. (thefreedictionary.com)
- All the eyes had a dense central leucomatous corneal opacity. (beds.ac.uk)
Methods2
- Scientists in our In-Vitro testing labs are well trained on ASTM, AATCC, AOAC, CLSI and EN standard methods. (biosciencelabs.com)
- Methods: We developed the clinical trial protocol based on international consensus statement on conditions for undertaking clinical trials of corneal xenotransplantation developed by the International Xenotransplantation Society. (elsevier.com)
Patients5
- In this video, Dr. Rushad Shroff and colleagues from India detail their approach for performing phacoemulsification in patients with corneal opacities. (aao.org)
- Treatment Options Although eye patches, topical antibiotics, and mydriatic agents traditionally have been used in patients with corneal abrasions, treatment recommendations recently have evolved. (keyword-suggest-tool.com)
- Three patients with a chief complaint of corneal opacity were transferred to our clinic from other clinics. (bvsalud.org)
- Patients with leucomatous corneal opacity with significant cataract were enrolled for the study. (beds.ac.uk)
- A prospective clinical trial was conducted at the Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, in which patients with leucomatous corneal opacity with a significant cataract were enrolled for the study. (beds.ac.uk)
Phototherapeutic keratectomy1
- The surgery may be performed using a laser, called phototherapeutic keratectomy (PTK), if the scarring is close to the corneal surface. (uvahealth.com)
Symptoms1
- If you experience any of these symptoms, do not assume it is due to corneal opacity. (knowyourdisease.com)
Corneas2
- The long-term goal of this project is to utilize newly available very high-speed OCT technology to guide surgical treatments of corneas with superficial opacities and irregularities. (clinicaltrials.gov)
- Each patient will undergo corneal xenotransplantation using fresh corneas from Seoul National University miniature pigs. (elsevier.com)
Clinical6
- To identify the long term clinical course of amblyopia and strabismus that developed secondary to a monocular corneal opacity following suspected epidemic keratoconjunctivitis (EKC) in infancy. (bvsalud.org)
- Accordingly, we aimed to prepare a clinical trial protocol to conduct the first corneal xenotransplantation. (elsevier.com)
- Conclusions: A detailed clinical trial protocol for the first corneal xenotransplantation reflecting the global guidelines is provided. (elsevier.com)
- Studies linking suppression of apoptosis in the acute wound-healing process with reduction of subsequent corneal scarring may have useful clinical applications. (nih.gov)
- Chalazion needs to be an important distinct regulatory mechanism for skeletal resistance in athymic mice lacking normal t lymphocytes.194 the htlv-infected, transformed cells is complexed to each detail of the lens 219 central opacities is of clinical oncology, cookridge hospital, leeds patient conformal therapy research radiographer, clatterbridge centre for oncology consultant radiologist, kingston hospital, surrey chief medical officers of england and the tip of the. (buffalo.edu)
- Wegener A, Jochims K. Clinical, histological and ultrastructural characteristics of a spontaneous corneal opacity in Sprague-Dawley rats. (springer.com)