AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesAnthropology, Education, Sociology and Social Phenomena
Corneal DiseasesNostrumsCorneaKeratitisKeratitis, HerpeticKeratitis, DendriticCorneal UlcerEye Infections, BacterialEpithelium, CornealCorneal TransplantationKeratoconusCorneal StromaCorneal Dystrophies, HereditaryKeratoplasty, PenetratingTearsMedicine, African TraditionalAcanthamoeba KeratitisBlindnessCorneal NeovascularizationContact LensesEndothelium, CornealHerpesvirus 1, HumanPseudomonas InfectionsConjunctivaVisual AcuityRabbitsMice, Inbred C57BLMice, Inbred BALB C
Corneal Diseases
Diseases of the cornea.
Nostrums
Medicines whose effectiveness is unproven and whose ingredients are often secret.
Cornea
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
Keratitis
Inflammation of the cornea.
Keratitis, Herpetic
A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed)
Keratitis, Dendritic
A form of herpetic keratitis characterized by the formation of small vesicles which break down and coalesce to form recurring dendritic ulcers, characteristically irregular, linear, branching, and ending in knoblike extremities. (Dictionary of Visual Science, 3d ed)
Corneal Ulcer
Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
Eye Infections, Bacterial
Infections in the inner or external eye caused by microorganisms belonging to several families of bacteria. Some of the more common genera found are Haemophilus, Neisseria, Staphylococcus, Streptococcus, and Chlamydia.
Epithelium, Corneal
Stratified squamous epithelium that covers the outer surface of the CORNEA. It is smooth and contains many free nerve endings.
Corneal Transplantation
Partial or total replacement of the CORNEA from one human or animal to another.
Keratoconus
A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)
Corneal Stroma
The lamellated connective tissue constituting the thickest layer of the cornea between the Bowman and Descemet membranes.
Corneal Dystrophies, Hereditary
Bilateral hereditary disorders of the cornea, usually autosomal dominant, which may be present at birth but more frequently develop during adolescence and progress slowly throughout life. Central macular dystrophy is transmitted as an autosomal recessive defect.
Keratoplasty, Penetrating
Partial or total replacement of all layers of a central portion of the cornea.
Tears
The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.
Medicine, African Traditional
A system of traditional medicine which is based on the beliefs and practices of the African peoples. It includes treatment by medicinal plants and other materia medica as well as by the ministrations of diviners, medicine men, witch doctors, and sorcerers.
Acanthamoeba Keratitis
Infection of the cornea by an ameboid protozoan which may cause corneal ulceration leading to blindness.
Blindness
The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.
Corneal Neovascularization
New blood vessels originating from the corneal veins and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.
Contact Lenses
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
Endothelium, Corneal
Single layer of large flattened cells covering the surface of the cornea.
Herpesvirus 1, Human
The type species of SIMPLEXVIRUS causing most forms of non-genital herpes simplex in humans. Primary infection occurs mainly in infants and young children and then the virus becomes latent in the dorsal root ganglion. It then is periodically reactivated throughout life causing mostly benign conditions.
Pseudomonas Infections
Infections with bacteria of the genus PSEUDOMONAS.
Conjunctiva
The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball.
Visual Acuity
Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.
Rabbits
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Mice, Inbred C57BL
Mice, Inbred BALB C

Causes of corneal graft failure in India. (1/900)

The success of corneal grafting in visual rehabilitation of the corneal blind in India depends on survival of the grafts. Understanding the causes of graft failure may help reduce the risk of failure. We studied these causes in a series of 638 graft failures at our institution. Multivariate logistic regression analysis was used to evaluate the association of particular causes of graft failure with indications for grafting, socioeconomic status, age, sex, host corneal vascularization, donor corneal quality, and experience of surgeon. The major causes of graft failure were allograft rejection (29.2%), increased intraocular pressure (16.9%), infection excluding endophthalmitis (15.4%), and surface problems (12.7%). The odds of infection causing graft failure were significantly higher in patients of lower socioeconomic status (odds ratio 2.45, 95% CI 1.45-4.15). Surface problems as a cause of graft failure was significantly associated with grafts done for corneal scarring or for regrafts (odds ratio 3.36, 95% CI 1.80-6.30). Increased intraocular pressure as a cause of graft failure had significant association with grafts done for aphakic or pseudophakic bullous keratopathy, congenital conditions or glaucoma, or regrafts (odds ratio 2.19, 95% CI 1.25-3.84). Corneal dystrophy was the indication for grafting in 12 of the 13 cases of graft failure due to recurrence of host disease. Surface problems, increased intraocular pressure, and infection are modifiable risk factors that are more likely to cause graft failure in certain categories of patients in India. Knowledge about these associations can be helpful in looking for and aggressively treating these modifiable risk factors in the at-risk categories of corneal graft patients. This can possibly reduce the chance of graft failure.  (+info)

Excimer laser ophthalmic surgery: evaluation of a new technology. (2/900)

The aim of this article is to provide information and an overview of the potential risks and benefits of excimer laser surgery, a new and promising technique in ophthalmic surgery. Although this review concentrates on the use of the laser for refractive purposes, novel therapeutic techniques are also discussed. It is hoped that this will enable general practitioners, optometrists and physicians to provide appropriate advice and counselling for patients.  (+info)

TNF-alpha production in the cornea in response to Pseudomonas aeruginosa challenge. (3/900)

Pseudomonas aeruginosa can cause ulcerative bacterial keratitis or contact lens-induced acute red eye (CLARE) in humans. The present study used a mouse model of ocular infection and inflammation to examine the relationship between TNF-alpha and inflammation in the cornea in response to challenge with either a strain of P. aeruginosa causing keratitis or a CLARE strain. Constitutive TNF-alpha mRNA was detected in the epithelium, mainly towards the periphery. After infection with the keratitis-inducing strain (6294), TNF-alpha expression was elevated four-fold by 24 h post-challenge. No detectable induction of TNF-alpha mRNA was seen with CLARE strain (Paer1) challenge at any time point. The TNF-alpha protein production detected by ELISA showed a corresponding pattern to the mRNA expression, which also correlated with pathological changes. These results suggest that invasive strains of P. aeruginosa create greater pathological changes as a result of elevated TNF-alpha production, which contributes to inflammation during keratitis in vivo.  (+info)

Matrix metalloproteinases in epithelia from human recurrent corneal erosion. (4/900)

PURPOSE: To assay for the presence of matrix metalloproteinases (MMPs) in human corneal epithelium affected by recurrent erosion compared with that in normal corneal epithelium. METHODS: Corneal epithelial debridement samples were obtained from 13 patients with recurrent epithelial erosion. For control specimens, epithelia were obtained from healthy patients undergoing photorefractive keratectomy. Zymography was performed on all samples to identify MMPs. Immunolocalization of MMP-2, laminin, and collagen type VII was determined in two samples with human recurrent epithelial erosion and compared with that in control epithelium. RESULTS: Twelve of 13 erosion samples showed MMP-2 enzymatic activity; one of the 12 also showed MMP-9 activity. Only one erosion sample showed no MMP enzymatic activity. All normal control specimens were negative for MMP. Immunohistochemical analysis of two recurrent erosion samples showed MMP-2 presence in basal cells, whereas, in normal epithelium it was not detected. One sample with epithelial erosion showed laminin localization in basal epithelial cells and basal lamina. Type VII collagen localized in basal epithelial cells only in this sample. A second erosion sample showed localization of laminin and type VII collagen in basal epithelial cells only. Normal corneal epithelium showed presence of laminin and type VII collagen in basal epithelium and basal lamina. CONCLUSIONS: Matrix metalloproteinase-2 expression is upregulated in human epithelia affected by recurrent erosion compared with that in normal control samples. Immunolocalization studies suggest that this enzyme is concentrated in basal epithelial cells where it may play an important role in degradation of the epithelial anchoring system and the recurrent epithelial slippage and erosion observed in these patients.  (+info)

Ocular ochronosis in alkaptonuria patients carrying mutations in the homogentisate 1,2-dioxygenase gene. (5/900)

AIMS: To assess the involvement of the recently identified human homogentisate 1,2-dioxygenase gene (HGO) in alkaptonuria (AKU) in two unrelated patients with ochronosis of the conjunctiva, sclera, and cornea. METHODS: A mutation screen of the entire coding region of the HGO gene was performed using single stranded conformational analysis after polymerase chain reaction with oligonucleotide primers flanking all 14 exons of the HGO gene. Fragments showing aberrant mobility were directly sequenced. RESULTS: Two homozygous missense mutations, L25P and M368V, were identified, each of which leads to the replacement of a highly conserved amino acid in the HGO protein. CONCLUSIONS: The authors describe a novel mutation, L25P, in the German population and bring to 18 the total number of known HGO mutations.  (+info)

Confocal microscopy in the iridocorneal endothelial syndrome. (6/900)

AIMS: To report the appearances of iridocorneal endothelial (ICE) syndrome from real time, white light confocal microscopy. METHODS: Three consecutive patients, each with ICE syndrome, were examined prospectively. Corneal specular and confocal microscopic examinations were performed in all three patients. In the first patient, a penetrating keratoplasty was performed and the cornea was examined by light and scanning electron microscopy. No surgery was performed in the remaining two patients. RESULTS: In the first patient corneal oedema prevented endothelial specular microscopy. Confocal microscopy performed before penetrating keratoplasty successfully revealed abnormal epithelial-like endothelial cells. Histological examinations of the cornea following penetrating keratoplasty revealed the presence of multilayered endothelial cells with epithelial features (microvilli). In the remaining two patients, specular microscopy showed the presence of ICE cells with typical dark/light reversal. Confocal microscopy demonstrated groups of endothelial cells with epitheloid appearances. In all three patients, the contralateral endothelial appearance was normal by specular and confocal microscopy, except for moderate endothelial polymegathism in one patient. Epithelial-like endothelial cells were characterised by prominent nuclei on confocal microscopy. CONCLUSIONS: The application of confocal microscopy indicates that the ICE syndrome is characterised by epitheloid changes in the endothelium. Confocal microscopy may be used to diagnose the ICE syndrome by demonstrating epithelial-like endothelial cells with hyperreflective nuclei. This technique is especially of value in cases of corneal oedema, since specular microscopy may fail to image the endothelium in such cases.  (+info)

Treatment of severe ocular-surface disorders with corneal epithelial stem-cell transplantation. (7/900)

BACKGROUND: Conditions that destroy the limbal area of the peripheral cornea, such as the Stevens-Johnson syndrome, ocular pemphigoid, and chemical and thermal injuries, can deplete stem cells of the corneal epithelium. The result is scarring and opacification of the normally clear cornea. Standard corneal transplantation cannot treat this form of functional blindness. METHODS: We performed and evaluated 70 transplantations of corneal epithelial stem cells from cadaveric eyes into 43 eyes of 39 patients with severe ocular-surface disorders and limbal dysfunction. Medical treatment had failed in all patients. The patients had a mean preoperative visual acuity of 0.004 (only being able to count the number of fingers presented by the examiner) in the affected eyes, which satisfies the criteria for legal blindness in most countries. In 28 eyes, we also performed standard corneal transplantation. Stem-cell transplantations were performed as many as four times on 1 eye if the initial results were not satisfactory; 19 eyes had multiple transplantations. Patients were followed for at least one year after transplantation. RESULTS: A mean of 1163 days after stem-cell transplantation, 22 of the 43 eyes (51 percent) had corneal epithelialization; of the 22 eyes, 7 eyes had corneal stromal edema and 15 eyes had clear corneas. Mean visual acuity improved from 0.004 to 0.02 (vision sufficient to distinguish the largest symbol on the visual-acuity chart from a distance of 1 m) (P<0.001). The 15 eyes in which the cornea remained clear had a final mean visual acuity of 0.11 (the ability to distinguish the largest symbol from a distance of 5 m). Complications of the first transplantation included persistent defects in the corneal epithelium in 26 eyes, ocular hypertension in 16 eyes, and rejection of the corneal graft in 13 of 28 eyes. The epithelial defects eventually healed in all but two of the eyes. CONCLUSIONS: Transplantation of corneal epithelial stem cells can restore useful vision in some patients with severe ocular-surface disorders.  (+info)

The p53 tumor suppressor gene of the marsupial Monodelphis domestica: cloning of exons 4-11 and mutations in exons 5-8 in ultraviolet radiation-induced corneal sarcomas. (8/900)

Inactivating p53 mutations are found in many ultraviolet radiation (UVR)-induced skin tumors. We examined 12 UVR-induced corneal tumors of the marsupial Monodelphis domestica for mutations in exons 5-8 of p53 and compared their mutational spectrum with that of UVR-induced skin tumors of other species. First we cloned and characterized a cDNA extending from the middle of exon 4 through exon 11 of the Monodelphis p53 gene. Based on the sequence information obtained, primers were designed to amplify introns 4-9 of the gene; intron primers to amplify individually exons 5-8 were subsequently developed. 'Cold' single strand conformational polymorphism analysis followed by reamplification of DNA with altered mobility and cycle sequencing revealed single p53 mutations in four of 12 tumors (33%), including one mutation in exon 5, two identical mutations in exon 7 and one mutation in exon 8. All mutations were at dipyrimidine sites and occurred on the non-transcribed strand. Three of the four were hallmark UVR-induced C-->T alterations. Three of the mutations were found at sites corresponding to human codons 248 and 273, which are mutational hotspots in human and murine UVR-induced squamous cell carcinomas. Our findings suggest that UVR-induced corneal sarcomas in Monodelphis will be valuable in studying mechanisms of p53 mutation in UVR-induced tumors.  (+info)

Recurrent Erosion Syndrome - New York CorneaRecurrent Erosion Syndrome - New York Cornea
Recurrent Erosion Syndrome (RES) is a spontaneous breakdown of the corneal epithelium (the outermost layer of the cornea). This occurs because the outer layer is weakly attached to the underlying membrane. The most common cause of Recurrent Erosion Syndrome is an initial minor corneal injury or abrasion, such as that caused by a fingernail. Other disease processes that can elicit Recurrent Erosion Syndrome include dystrophies, infections, diabetes, and dry eyes.. ...
http://newyorkcornea.com/recurrent-erosion-syndrome/
Study of DE-105 Ophthalmic Solution in Patients With Persistent Corneal Epithelial Defect - AdisInsightStudy of DE-105 Ophthalmic Solution in Patients With Persistent Corneal Epithelial Defect - AdisInsight
This study investigated DE-105 in patients with persistent corneal epithelial defect. The primary endpoint was restoration of corneal epithelial defect assessed
http://adisinsight.springer.com/trials/700244155?error=cookies_not_supported&code=9ecbda7f-2ab1-4864-a188-c48629f1bd61
Corneal Pathogenesis of Staphylococcus aureus Strain Newman | IOVS | ARVO JournalsCorneal Pathogenesis of Staphylococcus aureus Strain Newman | IOVS | ARVO Journals
This study also suggests that α-toxin is active in producing ocular changes in eyes infected with strain Newman. All the Newman strains, except the one deficient in α-toxin, produced corneal epithelial erosions that were readily visible on gross examination and in histologic sections of corneas. Corneal erosions produced by the γ-toxin-deficient Newman strain, but not the α-toxin-deficient mutant, are evidence for a role for α-toxin in corneal epithelial erosion produced by strain Newman. Also, supporting a role for α-toxin in the corneal virulence of strain Newman was the protection against corneal damage, especially epithelial erosion, afforded by either active or passive immunization to α-toxin. The epithelial erosions caused by Newman strains developed more slowly and were smaller throughout the 25 hours of infection than those caused by strain 8325-4, a strain in which α-toxin is the key hemolytic toxin. This difference in the rate of erosion formation correlates with the relatively ...
http://iovs.arvojournals.org/article.aspx?articleid=2200172
Common Genetic Variants near the Brittle Cornea Syndrome Locus ZNF469 Influence the Blinding Disease Risk Factor...Common Genetic Variants near the Brittle Cornea Syndrome Locus ZNF469 Influence the Blinding Disease Risk Factor...
Terri L. Young, M.D., M.B.A. is a board-certified clinician-scientist ophthalmologist. She is a Professor of Ophthalmology, Pediatrics, and Medicine at Duke University School of Medicine. She is a Professor of Neuroscience at the Duke- National University of Singapore Graduate Medical School, with adjunct appointments at the Singapore Eye Research Institute and the Saw Swee Hock School of Public Health, National University of Singapore. She is the founding Director of the Duke ...
https://dukespace.lib.duke.edu/dspace/handle/10161/4467
SOPHiA GENETICS - Bruchs membrane abnormalities in PRDM5-related brittle cornea syndrome
For Research Use Only. Not for Use in Diagnostic Procedures. The information included has been prepared for and is intended for viewing by a global audience. Information about products which may or may not be available in different countries and if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please consult local sales representatives.. © 2021 SOPHiA GENETICS. All rights reserved. All trademarks are the property of SOPHiA GENETICS and/or its affiliate(s) in the U.S. and/or other countries. All other names, logos, and other trademarks are the property of their respective owners. ...
https://www.interactive-biosoftware.com/media-center/literature/bruchs-membrane-abnormalities-in-prdm5-related-brittle-cornea-syndrome/
Dystrophia Smolandiensis - recurrent corneal erosions with a novel morphological pictureDystrophia Smolandiensis - recurrent corneal erosions with a novel morphological picture
Recurrent corneal erosions are a common complication of superficial corneal wounds. They most commonly arise following a trauma, in association with various corneal dystrophies, or are idiopathic.. The main aim of this thesis was to investigate two hereditary corneal diseases with recurrent erosions in order to find out if they had been described before, and more specifically to describe the clinical picture and the morphological changes, differentiate them from other known autosomal dominant corneal dystrophies with a clinical resemblance, and to exclude genetic linkage to known corneal dystrophies with autosomal-dominant inheritance and a clinical resemblance.. The thesis is based on two families of subjects belonging to different phenotypes. The subjects from Småland (Dystrophia Smolandiensis) belonged to a six-generation family, which included 171 individuals of whom 44 were affected individuals, and the family from Hälsingland (Dystrophia Helsinglandica) included sevengenerations of 342 ...
http://liu.diva-portal.org/smash/record.jsf?pid=diva2:209704
Prevalence of corneal diseases in the rural Indian population: the Corneal Opacity Rural Epidemiological (CORE) study | British...Prevalence of corneal diseases in the rural Indian population: the Corneal Opacity Rural Epidemiological (CORE) study | British...
Results Overall, 12 113 of 12 899 people (93.9% response rate) were examined during the household visits. Prevalence of corneal disease was 3.7% (95% CI 3.4% to 4.1%) and that of corneal blindness was 0.12% (95% CI 0.05% to 0.17%). Multivariable analysis demonstrated that corneal disease was significantly higher in the elderly (p,0.0001) and illiterates (p,0.0001). Common causes of corneal opacity in the study population were pterygium (34.5%), ocular trauma (22.3%) and infectious keratitis (14.9%). Corneal diseases contributing to blindness were post-surgical bullous keratopathy (46.2%) and corneal degenerations (23.1%).. ...
https://bjo.bmj.com/content/99/2/147
Combined PRK and PTK in myopic patients with recurrent corneal erosion | British Journal of OphthalmologyCombined PRK and PTK in myopic patients with recurrent corneal erosion | British Journal of Ophthalmology
There are several reports on the treatment of recalcitrant recurrent corneal erosion syndrome by excimer laser PTK.23-31 The reported rate of success, regarding alleviation of symptoms and prevention of recurrence of epithelial erosion, ranges between 74.4% and 100%.23-31 Dauschet al 23 reported a success rate of 74.4% in 74 eyes treated by PTK. OBrart et al 27reported that four out of 17 eyes (23.5%) experienced recurrent episodes 3-6 months after PTK and two have subsequently been retreated, one of whom has been symptom free for 12 months following retreatment. Postoperative BVA was unaltered in nine eyes and improved by at least one Snellen line in eight eyes. Both Forster et al 31 and Algawi et al 24 reported that none of their treated patients had experienced recurrence of corneal erosion. However, Algawi et al24 reported that two of 14 patients still complained of transient, recurrent foreign body sensation following PTK, although none of their patients developed recurrence of the ...
http://bjo.bmj.com/content/81/7/551
New approaches to the diagnosis and management of important corneal disorders in the cataract and refractive surgery patient |...New approaches to the diagnosis and management of important corneal disorders in the cataract and refractive surgery patient |...
Enjoy this 7-page print monograph focused on the importance of and best practices for diagnosis and management of important corneal disorders in the cataract and refractive surgery patient ...
https://ascrs.org/clinical-education/earn-and-claim-cme/earn-cme/2020ewsuppjano-new-approaches-to-the-diagnosis-and-management-of-important-corneal-disorders-in
Role of bandage contact lens in corneal disorders: A review-IJOOO-IP Innovative Publication Pvt. LtdRole of bandage contact lens in corneal disorders: A review-IJOOO-IP Innovative Publication Pvt. Ltd
Role of bandage contact lens in corneal disorders: A review-IJOOO-Print ISSN No:-2581-5024 Online ISSN No:-2581-5016Article DOI No:-10.18231/j.ijooo.2019.060,IP International Journal of Ocular Oncology and Oculoplasty-IP Innovative Publication Pvt Limited, Medical Journals Publication, Open Access Journals, Print Jou
https://www.ipinnovative.com/journals/IJOOO/article-details/10385/volume/244/issue/804
Cooper Eye Care | Corneal Disorders - Cooper Eye CareCooper Eye Care | Corneal Disorders - Cooper Eye Care
CORNEAL ABRASION Corneal abrasions, a cut or scratch of the clear window of the eye, are associated with light sensitivity, pain, and tearing. Corneal abrasions may cause mild discomfort or severe pain, depending on the size of the abrasion. Treatment may include lubrication, bandage contact lens, eye patching and/or preventative antibiotic ointment. The cornea is the fastest healing tissue in the human body, thus, most corneal abrasions will heal within 24-36 hours.. BAND KERATOPATHY Band keratopathy is a calcium deposit at the 3-9 oclock positions in the front layer of the cornea. This deposit of calcium may spread across the cornea in band like appearance. The condition is caused by inflammations, trauma, chronic ocular disease, or even systemic diseases.. Treatment is necessary when the deposits affect vision. If the band of calcium deposits affect visions, chemical removal can be considered. Usually, vision improves following the removal of calcium from the cornea.. CORNEAL DELLEN Dellen ...
http://coopereyecare.com/eye-problems/corneal-disorders/
Recurrent Erosion Syndrome and Epithelial Edema - In Vivo | Helena M. Tabery | SpringerRecurrent Erosion Syndrome and Epithelial Edema - In Vivo | Helena M. Tabery | Springer
Presents high-magnification in vivo images of the morphology of recurrent corneal erosions and epithelial edema as captured by non-contact
http://www.springer.com/us/book/9783319065441
Corneal Disorders | Optometrist in Media, PA | Vision Care of Media
Corneal Disorders in Media, PA. Vision Care of Media is your local Optometrist in Media serving all of your needs. Call us today at (610) 566-2744 for an appointment.
https://www.visioncareofmedia.com/articles/general/category/39805
Corneal Disorders | Optometrist in Milwaukee, WI | Design Vision OpticalCorneal Disorders | Optometrist in Milwaukee, WI | Design Vision Optical
Corneal Disorders in Milwaukee, WI. Design Vision Optical is your local Optometrist in Milwaukee serving all of your needs. Call us today at (414) 774-0200 for an appointment.
https://designvisionoptical.com/articles/general/category/39805
Introduction to Corneal Disorders - Eye Disorders - Merck Manuals Consumer VersionIntroduction to Corneal Disorders - Eye Disorders - Merck Manuals Consumer Version
Introduction to Corneal Disorders - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version.
https://www.merckmanuals.com/en-ca/home/eye-disorders/corneal-disorders/introduction-to-corneal-disorders
Introduction to Corneal Disorders - Eye Disorders - MSD Manual Consumer VersionIntroduction to Corneal Disorders - Eye Disorders - MSD Manual Consumer Version
Introduction to Corneal Disorders - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version.
https://www.msdmanuals.com/en-nz/home/eye-disorders/corneal-disorders/introduction-to-corneal-disorders
Corneal Disorders: Clinical Diagnosis and ManagementCorneal Disorders: Clinical Diagnosis and Management
Find all books from Howard M. Leibowitz, Waring Leibowitz, Richard Lampert - Corneal Disorders: Clinical Diagnosis and Management. At find-more-books.com you can find used, antique and new books, COMPARE results and immediately PURCHASE your selection at the best price. 9780721658674
https://www.find-more-books.com/book/isbn/9780721658674.html
Corneal Disorders | Optometrist in Aurora, Colorado | Burcham Eyecare Center
Corneal Disorders in Aurora, Colorado. Burcham Eyecare Center is your local Optometrist in Aurora serving all of your needs. Call us today at 3033404600 for an appointment.
https://denver-eye.com/articles/general/category/39805
Corneal Disorders | Optometrist in Emory, TX | Emory EyecareCorneal Disorders | Optometrist in Emory, TX | Emory Eyecare
Corneal Disorders in Emory, TX. Emory Eyecare is your local Optometrist in Emory serving all of your needs. Call us today at (903) 474-9090 for an appointment.
https://emoryeyecare.com/articles/general/category/39805
Recurrent Corneal Erosion in Adults: Condition, Treatments, and Pictures - Overview | skinsightRecurrent Corneal Erosion in Adults: Condition, Treatments, and Pictures - Overview | skinsight
The treatment for recurrent corneal erosion is very similar to that for corneal abrasion. Patching is often very helpful, usually after the instillation of an antibiotic ointment. The doctor may teach you how to open your eye carefully and remind you never to rub the eye. If there is an underlying corneal disease requiring treatment, that too will be addressed. Often, you will be given a salt-like drop for day use and salt-like ointment for nighttime use. The salt pulls fluid out of the corneal epithelium, allowing it to lay down tighter to the underlying basement membrane and, hence, heal better. Map-dot fingerprint dystrophy, which most patients dont know they have, usually resolves over several years on its own without treatment. Some patients may also be taught how to apply a tight patch that restricts eye movement at night and upon waking so there is less likelihood of recurrence. If these rather simple procedures are not successful, the eye care professional may re-scrape the area to ...
https://www.skinsight.com/skin-conditions/adult/recurrent-corneal-erosion
Recurrent corneal erosion - Alex Shortt | London Eye SurgeonRecurrent corneal erosion - Alex Shortt | London Eye Surgeon
Recurrent corneal erosion (RCE) is a repeated breakdown on the surface of the eye causing severe eye pain, light-sensitivity, tearing, and corneal scarring leading to visual changes...
https://www.alexshortt.co.uk/recurrent-corneal-erosion/
ICD-10 Diagnosis Code H18.832 Recurrent erosion of cornea, left eyeICD-10 Diagnosis Code H18.832 Recurrent erosion of cornea, left eye
Diagnosis Code H18.832 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
https://icdlist.com/icd-10/h18832
Corneal Changes in Diabetes Mellitus | Bentham ScienceCorneal Changes in Diabetes Mellitus | Bentham Science
Title:Corneal Changes in Diabetes Mellitus. VOLUME: 8 ISSUE: 4. Author(s):Guzel Bikbova, Toshiyuki Oshitari, Ayako Tawada and Shuichi Yamamoto. Affiliation:Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Inohana 1-8-1, Chuo-ku, Chiba 260-8670, Chiba, Japan.. Keywords:Advanced glycation end-products, corneal wound healing, diabetes mellitus, endothelial cell dysfunction, epithelial defect, growth factors, neurotrophic keratopathy, vitrectomy, keratopathy, diabetic polyneuropathy. Abstract:Diabetes mellitus is a major disease worldwide, and the prevalence of diabetes has risen significantly in the past several decades. Although one of the major complications of diabetic eyes is diabetic retinopathy (DR), corneal diseases can not only develop in diabetic patients but are also difficult to manage. Diabetic neurotrophic keratopathy is a component of diabetic polyneuropathy and is recognized to be the cause of the morbidity of the cornea in diabetic ...
http://www.eurekaselect.com/99387/article?tracking-code=4
Genetic Evidence for Differential Regulation of Corneal Epithelial and Stromal Thickness | IOVS | ARVO JournalsGenetic Evidence for Differential Regulation of Corneal Epithelial and Stromal Thickness | IOVS | ARVO Journals
To date, GWAS in humans have identified 27 CCT-associated loci,13,16,23-25 and QTL analysis in mice has identified 6 CCT-associated loci. Some of the genes identified in GWAS were independently identified as CCT regulators because of their association with rare connective tissue disorders (i.e., brittle cornea syndrome and osteogenesis imperfecta).11,12,15 The genes identified by GWAS show an enrichment of pathways involving collagen and extracellular matrix (ECM), which might be expected since the cornea is composed largely of an ECM-rich stroma. Other CCT-influencing genes (e.g., Twist2, Bnc1, Bcl-2, and Bax) have been identified through studies that used candidate-driven approaches.44-46 A comparison of the syntenic regions of Cctq4 indicated that this locus overlaps partially with Tiparp, a locus previously reported to be associated with CCT in humans based on a meta-analysis by Lu et al.16 However, Tiparp is unlikely to be the gene underlying the association between Cctq4 and CCT because it ...
http://iovs.arvojournals.org/article.aspx?articleid=2430903
Corneal Disorders - Merck Manuals Consumer VersionCorneal Disorders - Merck Manuals Consumer Version
Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Manual was first published in 1899 as a service to the community. The legacy of this great resource continues as the Merck Manual in the US and Canada and the MSD Manual outside of North America. Learn more about our commitment to Global Medical Knowledge.. ...
http://www.merckmanuals.com/en-pr/home/eye-disorders/corneal-disorders
What is congenital corneal disease and what is congenital corneal disease treatment? | Samer Hamada | Eye Clinic LondonWhat is congenital corneal disease and what is congenital corneal disease treatment? | Samer Hamada | Eye Clinic London
When your child was born, you may have been told by the nurse that there is something wrong with their eyes. They may have advised you to see a specialist.
https://eyecliniclondon.com/what-is-congenital-corneal-disease-and-what-is-congenital-corneal-disease-treatment/
Corneal DiseasesCorneal Diseases
Cornerstone Eye Associates provides several effective treatments for corneal diseases in Rochester, NY. Call today to schedule your appointment!
http://www.cornerstoneeye.com/eye-conditions/corneal-diseases/
Lasik Eye Surgery • View topic - extreme pain, red eye, blurriness:recurrent corneal erosion?
The corneal epithelial cells are the fastest reproducing cells in the human body, but it will take time for them to cover the area, thicken, and smooth. You will undoubtedly have some corneal edema (inflammation) from the insult, which will cause fluctuations in your refractive error and likely an uneven healing pattern until things settle down. Your poor vision will wax and wane and change over the next 2-3 weeks. You will likely not get the really good vision you want until 4-6 weeks or even a bit longer. You will undoubtedly have functional vision within a week, but you wont be threading any needles with that eye ...
http://www.usaeyes.org/ask-lasik-expert/viewtopic.php?p=9728
Diabetic corneal neuropathy: clinical perspectives | OPTHDiabetic corneal neuropathy: clinical perspectives | OPTH
Diabetic corneal neuropathy: clinical perspectives Guzel Bikbova,1,2 Toshiyuki Oshitari,1 Takayuki Baba,1 Mukharram Bikbov,2 Shuichi Yamamoto1 1Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan; 2Cornea and Refractive Surgery Department, Ufa Eye Research Institute, Ufa, Russia Abstract: Diabetic keratopathy is characterized by impaired innervation of the cornea that leads to decreased sensitivity, with resultant difficulties with epithelial wound healing. These difficulties in wound healing put patients at risk for ocular complications such as surface irregularities, corneal infections, and stromal opacification. Pathological changes in corneal innervations in diabetic patients are an important early indicator of diabetic neuropathy. The decrease in corneal sensitivity is strongly correlated with the duration of diabetes as well as the severity of the neuropathy. This review presents recent findings in assessing the ocular surface as well as the
https://www.dovepress.com/diabetic-corneal-neuropathy-clinical-perspectives-peer-reviewed-article-OPTH
Lasik Eye Surgery • View topic - extreme pain, red eye, blurriness:recurrent corneal erosion?
I took my defect a little longer to heal, (I dont know if it was because the flap was lifted before it healed) ,it healed rapidly and then slowed. But it closed Yesterday, and that was my worse vision day thus far. It was so so blurry it made my head swim. However I still have some DLK inflammation that has persisted around the edge of my flap and he has increased my steroid drops and oral steroids a little. But other that that my vision isnt as bad today. But it is still a blurry mess overall ...
http://www.usaeyes.org/ask-lasik-expert/viewtopic.php?p=10142
recurrent corneal erosion syndrome | Eye Problems | Forums | Patientrecurrent corneal erosion syndrome | Eye Problems | Forums | Patient
I had this condition un-diagnosed for many years its frequency has increased from once a year to twice a month or so. Eye drops such as...
https://patient.info/forums/discuss/recurrent-corneal-erosion-syndrome-34735
Most recent papers with the keyword Cornea pannus | Read by QxMDMost recent papers with the keyword Cornea pannus | Read by QxMD
Purpose. To report a case of a patient with rheumatoid arthritis (RA) treated with tofacitinib citrate. Methods. Observational case report. Results. A 59-year-old patient, with a history of rheumatoid arthritis, on methotrexate 10 mg PO qwk and IV abatacept 750 mg/month, presented with photosensitivity, foreign body sensation, pain, redness, and blurry vision of her right eye (RE). Visual acuity of the RE was 20/200 and 20/20 of the left eye (LE). The slit lamp examination of the RE revealed dryness, 2+ injection of the conjunctiva, and pericentral ulceration of the cornea with 20-30% stromal thinning, pannus, and diffuse punctate epithelial erosions ...
https://www.readbyqxmd.com/keyword/83464
A Clinical Case from the Archives : 09/01/2011 | Veterinary ophthalmologyA Clinical Case from the Archives : 09/01/2011 | Veterinary ophthalmology
This is lipid deposition with associated blood vessels probably after a corneal ulcer. Wed call this a lipid keratopathy, though Ive never seen one in a cat before and cant find a report of it in the literature. Not enough money, or a calm enough cat, to take a blood sample for lipid analysis Im afraid, but as the cat is happy no treatment is needed. If it were maybe the driver of this truck I passed on the way home from the consultation would be able to help! ...
http://davidlwilliams.org.uk/?p=1286
Ocular Diagnostic Preparations. Ocular Diagnostic Info | PatientOcular Diagnostic Preparations. Ocular Diagnostic Info | Patient
read Ocular Diagnostic Preparations for- tear film assessment, identification of corneal epithelial defects/corneal disease and more about Ocular Diagnostic Preparations
https://patient.info/doctor/ocular-diagnostic-preparations
Band Shaped Keratopathy<...Band Shaped Keratopathy<...
Find information on Band Shaped Keratopathy : Introduction, Symptoms, Causes, Diagnosis, Management , Prevention - www.genericdrugscan.com
http://www.genericdrugscan.com/disease/band-shaped-keratopathy
Corneal Disease: Explanation, Symptoms, and Treatment | Anne Arundel Eye CenterCorneal Disease: Explanation, Symptoms, and Treatment | Anne Arundel Eye Center
Your cornea - the clear, protective outer layer of the eye - not only protects your eye from dirt and germs, but also plays a key role in your vision. As light
https://annearundeleyecenter.com/2017/10/corneal-disease-explanation-symptoms-and-treatment/
FrumSupport Forums - Corneal Diseases
The information in this site is not intended to replace the advice of a doctor. FrumSupport disclaims any liability for the decisions you, the User, makes based on information on this site. By using this site, reading, viewing, posting or otherwise, you signify your assent to the Terms and Conditions of Use. If you do not agree to all these Terms and Conditions of Use, please do not use this site. FrumSupport may revise and update these Terms and Conditions of Use at anytime. Your continued usage of FrumSupport will mean you accept those changes. If you think you or someone you know has a medical emergency, call your doctor, Hatzolah or 911 immediately. FrumSupport cannot and does not monitor forums and postings and cannot and will not pro-actively obtain help for users in need as FrumSupport does not have the funds or people power to accomplish such tasks and it will infringe on the anonymity of each user. Therefore, FrumSupports liability is limited by this paragraph and as further set forth ...
http://www.frumsupport.com/forums/categories.cfm?FTVAR_SUBCAT=135&catid=137&subcatname=Ophthalmology
Ocular Pathology: Band Keratopathy
Etiology: Band keratopathy derives its name from the distinctive appearance of calcium deposition in a band across the central cornea. Band keratopathy can occur from a variety of causes, both systemic and local. Bank keratopathy is associated with chronic corneal edema (perhaps the most common treatable cause accounting for over 1/4 of cases in one series), phthisis bulbi, chronic iridocyclitis, severe glaucoma, hyperparathyroidism, vitamin D excess, sarcoidosis or renal disease. The latter 4 are related to abnormal calcium metabolism. Severe dry eye may also precede band keratopathy. Herpes keratitis may predispose to band keratopathy. The use of phosphate salts in steroid preparations may precipitate calcium in patients with epithelial defects ...
http://www.images.missionforvisionusa.org/anatomy/2007/02/band-keratopathy.html
Limits of immunohistochemistry in the diagnosis of epithelial downgrowth<...Limits of immunohistochemistry in the diagnosis of epithelial downgrowth<...
TY - JOUR. T1 - Limits of immunohistochemistry in the diagnosis of epithelial downgrowth. AU - Bergwerk, K. L.. AU - Rosenbaum, P. S.. AU - Tanaka, K. E.. AU - Udeil, I. J.. PY - 1996/2/15. Y1 - 1996/2/15. N2 - Purpose: The immunohistochemical staining characteristics of corneal endothelium was studied to clarify the usefulness of these stains in the pathologic diagnosis of epithelial downgrowth. Methods: Tissue sections of formalin-fixed, paraffin-embedded corneal specimens (keratoconus, pseudophakic bullous keratopathy, epithelial downgrowth, failed corneal grafts with retrocorneal fibrous membranes, and postmortem control corneas) were immunostained with a panel of corneal epithelial and endothelial markers (EMA, KAE 1/3, CAM5.2, Factor VIII, CD-34, CD-31) and with Vimentin using the Strept-Avidin technique (Dako). Results: Corneal endothelium is immunonegative for endothelial cell markers (CD-34,CD-31, and Factor VIII) and displays immunopositivity for epithelial markers (KAE 1/3, CAM 5.2). ...
https://einstein.pure.elsevier.com/en/publications/limits-of-immunohistochemistry-in-the-diagnosis-of-epithelial-dow-2
Manual Intracorneal Silicone Oil Insertion for Symptomatic Treatment of Bullous Keratopathy in a Patient with Corneal ScarringManual Intracorneal Silicone Oil Insertion for Symptomatic Treatment of Bullous Keratopathy in a Patient with Corneal Scarring
Case Report DOI:10.14744/bej.2019.79553 Beyoglu Eye J 2019; 4(2): 126-129 Manual Intracorneal Silicone Oil Insertion for Symptomatic Treatment of Bullous Keratopathy in a Patient with Corneal Scarring Selim Genc, Semih Cakmak, Yusuf Yildirim Department of Ophthalmology, University of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey Abstract Bullous keratopathy is a result of endothelial loss and the failure of the remaining corneal epithelium to pump leaking water molecules away from the corneal tissue, causing overhydration. In eyes with good visual potential, keratoplasty is the primary treatment. There are also several other approaches to provide temporary improvement until a permanent solution with keratoplasty can be achieved. These alternatives include hypertonic topical sodium chloride (5%) drops, bandage contact lenses, anterior stromal puncture, phototherapeutic keratectomy, amniotic membrane transplantation, conjunctival flaps, and collagen crosslinking. ...
https://studylibtr.com/doc/5903459/manual-intracorneal-silicone-oil-insertion-for-symptomati.
Autologous cultivated limbal stem cell transplantation after failed previous limbal graft<...
TY - JOUR. T1 - Autologous cultivated limbal stem cell transplantation after failed previous limbal graft. AU - Knutsson, KA. AU - Matuska, S. AU - Rama, P. PY - 2017. Y1 - 2017. N2 - Purpose: To describe a case of unilateral limbal stem cell deficiency (LSCD) with previously failed autologous graft, resolved by ocular surface reconstruction using cultured autologous limbal stem cells from the contralateral eye. Case report: A 35-year-old patient presented to our clinic with LSCD due to a unilateral alkali burn. The patient had received a previous limbal graft from the contralateral eye that had failed to impede corneal conjunctivalization. We decided to repeat limbal stem cell transplantation using an ex vivo cultivation procedure to reduce the risk of tissue harvesting on the healthy fellow eye. A small limbal biopsy (1.5 × 1.5 mm) near the previously excised limbus was performed. Stem cells were then isolated and cultured on fibrin and a 3T3 feeder cell layer using a standard protocol. Four ...
https://moh-it.pure.elsevier.com/en/publications/autologous-cultivated-limbal-stem-cell-transplantation-after-fail
Most recent papers with the keyword examination of cranial nerv | Read by QxMDMost recent papers with the keyword examination of cranial nerv | Read by QxMD
PURPOSE: We report our experience with the use of maternally derived serum eye drops as adjunctive treatment in the management of pediatric persistent corneal epithelial defects. METHODS: Five eyes of 4 patients were identified in a retrospective review of pediatric patients with persistent corneal epithelial defects who received maternal serum drops. Diagnoses associated with the defects comprised pontine tegmental cap dysplasia with bilateral cranial nerve V1, V2, V3, and VII palsies; pontine tegmental cap dysplasia with left cranial nerve V1, VII, and VIII palsies; traumatic left cranial nerve II, V1, V2, and VI palsies due to a basilar skull fracture; and Stevens-Johnson syndrome with ocular involvement ...
https://www.readbyqxmd.com/keyword/21464
Treatment of ocular surface diseases with limbal and conjunctival stem cells
Abstract Objective: A population of stem cells (SCs) is responsible for maintenance and repair of the ocular surface. These stem cells can become deficient as a result of various diseases affecting the ocular surface. Depending on the extent of damage, the clinical features can vary from mild discomfort to substantial pain and/or blindness. The growing field of tissue engineering and advances in stem cell research offer promising new alternatives for these disorders. This student thesis will provide an overview of the human ocular surface (cornea, limbus, and conjunctiva), ocular surface stem cell deficiency, and treatment possibilities. Methods: This student thesis is based on a number of review articles and original articles on PubMed using the search words limbal, limbal stem cell deficiency, conjunctival and/or ocular surface reconstruction. Only papers written in English were considered. Findings: There are different possible methods for treating ocular surface stem cell deficiency by ...
https://www.duo.uio.no/handle/10852/38925
Altered Signaling Pathways in Aniridia-Related KeratopathyAltered Signaling Pathways in Aniridia-Related Keratopathy
Aniridia is a congenital autosomal dominant, bilateral, panocular condition, caused by haploinsufficiency of the Pax6 transcription factor. Aniridia-related keratopathy (ARK) significantly affects vision and quality of life in these patients. ARK is a chronic progressive keratopathy comprising limbal stem cell deficiency associated with impaired epithelial cell adhesion, corneal conjunctivalization, epithelial erosions and corneal vascular pannus that typically only appear after childhood.. The aims were i) to evaluate the structural changes and ii) cell signaling pathways, including the Notch1, Sonic Hedgehog (SHH), mTOR and Wnt/beta-catenin cell signaling pathways in naïve and surgically treated corneas of aniridia cases with advanced ARK and comparing with normal human adult and fetal corneas and iii) to develop a corneal cell culture model of aniridia.. Naïve ARK corneas removed at the time of the first transplantation and ARK corneal buttons removed after a failed keratolimbal allograft ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2%3A1276576&c=12&searchType=SIMPLE&language=en&query=&af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22authority-person%3A65169%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
Band Keratopathy: Background, Etiology, PrognosisBand Keratopathy: Background, Etiology, Prognosis
Band keratopathy is characterized by the appearance of a band across the central cornea, formed by the precipitation of calcium salts on the corneal surface (directly under the epithelium). This form of corneal degeneration can result from a variety of causes, either systemic or local, with visual acuity decreasing in proportion to the densit...
https://emedicine.medscape.com/article/1194813-overview
Cornea Transplant Surgery - New York CorneaCornea Transplant Surgery - New York Cornea
Corneal transplant surgery is the most commonly performed of all transplant operations, with approximately 45,000 corneal transplant procedures being performed in the Unites States each year. The indications for corneal transplant surgery have changed through the years. Pseudophakic bullous keratopathy and aphakic bullous keratopathy (corneal edema secondary to cataract surgery) accounted for 80% of corneal transplants in the 1980s. However, with the improvement of cataract surgery techniques, conditions such as Fuchs Dystrophy, Keratoconus, and other corneal dystrophies are now more commonly transplanted.. In 1933, corneal transplants were performed using two razor blades to make a square graft. Patients were hospitalized for two weeks with sand bags on either side of their head to prevent undesirable movement and possible leakage from the wound sites. Since then, there have been major advances in surgical technique including the introduction of the operating microscope (1970s) and better ...
http://newyorkcornea.com/cornea-transplant-surgery/
Corneal Disorders | Optometrist in Rochelle, IL | Family Vision Center Family Vision Center - Optometry in Rochelle, IL USCorneal Disorders | Optometrist in Rochelle, IL | Family Vision Center Family Vision Center - Optometry in Rochelle, IL US
Corneal Disorders in Rochelle, IL. Family Vision Center is your local Optometrist in Rochelle serving all of your needs. Call us today at (815) 562-7077 for an appointment.
https://www.fvcrochelle.com/articles/general/category/39805
Corneal Disorders | Optometrist in Fort Smith, AR | Arkansas Vision Development Center Arkansas Vision Development Center -...Corneal Disorders | Optometrist in Fort Smith, AR | Arkansas Vision Development Center Arkansas Vision Development Center -...
Corneal Disorders in Fort Smith, AR. Arkansas Vision Development Center is your local Optometrist in Fort Smith serving all of your needs. Call us today at (479) 478-8860 for an appointment.
https://www.arkansasvision.com/articles/general/category/39805
Corneal Disorders | Optometrist in McAllen, TX | Roberto Olivarez Jr., ODCorneal Disorders | Optometrist in McAllen, TX | Roberto Olivarez Jr., OD
Corneal Disorders in McAllen, TX. Roberto Olivarez Jr., OD is your local Optometrist in McAllen serving all of your needs. Call us today at (956) 664-0240 for an appointment.
https://www.northmcallenoptometry.com/community-content/general/category/39805
Kyoto Prefectural University reports clinical study on corneal endothelial cell transplantation against bullous keratopathy |...Kyoto Prefectural University reports clinical study on corneal endothelial cell transplantation against bullous keratopathy |...
Bullous keratopathy is a condition where corneal endothelial cells, which do not normally proliferate in vivo, are extensively impaired by trauma, disease, surgery or the like and do not longer maintain the transparency of the cornea, leading to edema and turbidity. Kyoto Prefectural University of Medicine and Doshisha University jointly expanded corneal endothelial cells derived from donors and injected them into the anterior chamber of patients with keratopathy. 11 cases of a clinical study now confirmed effectiveness and safety of this treatment.. AMED news release, March 15, 2018. ...
https://window-to-japan.eu/2018/03/15/kyoto-prefectural-university-reports-clinical-study-on-corneal-endothelial-cell-transplantation-against-bullous-keratopathy/
Morselized Amniotic Membrane Tissue for Refractory Corneal Epithelial Defects in Cicatricial Ocular Surface Diseases | TVST |...Morselized Amniotic Membrane Tissue for Refractory Corneal Epithelial Defects in Cicatricial Ocular Surface Diseases | TVST |...
The Table summarizes the patients demographics, ocular comorbidity, concomitant treatment, and clinical manifestations including symptoms and signs at the presentation. Conjunctival inflammation was graded according to the conjunctival injection as none (0), mild (1), moderate (2), and severe (3). The corneal surface integrity was scored as clear (0), scattered superficial punctuate keratitis (SPK; 1+), moderate SPK (2+), and diffuse SPK with or without corneal epithelial defects (3+). The tear function was assessed by the fluorescein clearance test as reported28 using the Schirmer paper strip following topical application of 5 μL of Fluroress (Akorn Inc., Abita Springs, LA). The diagnosis of dry eye disease (DED) was based on the wetting length of less than 3 mm at the 10th and 20th minute. For Case #2 who presented with epithelial basement membrane dystrophy (EBMD), the diagnosis was confirmed by observing corneal epithelial wrinkles or breaks by the screwdriver test, which applies a dry ...
http://tvst.arvojournals.org/article.aspx?articleid=2524682
Recurrent Corneal Erosion - EyeWikiRecurrent Corneal Erosion - EyeWiki
Recurrent Corneal Erosion (RCE) syndrome is a common, recurrent condition caused by abnormal epithelial adhesion to the underlying basal lamina. The spontaneous breakdown of the corneal epithelium can lead to the sudden onset of ocular pain, blurred vision, tearing, and photophobia, typically upon awakening.[1][2][3]
https://eyewiki.org/Recurrent_Corneal_Erosion
Cultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell Deficiency - Full Text View - ClinicalTrials.govCultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell Deficiency - Full Text View - ClinicalTrials.gov
A limbal biopsy taken from the contralateral good eye in cases of unilateral disease or from a living related or cadaveric donor in cases of bilateral disease. The limbal stem cells from the biopsy are cultivated until a sheet of cells measuring approximately 12mm in diameter is obtained. This is then ready for transplantation onto the diseased eye ...
https://clinicaltrials.gov/ct2/show/NCT00845117?recr=Open&cond=%22Stem+Cells%22&rank=16
Corneal erosion syndrome | definition of corneal erosion syndrome by Medical dictionaryCorneal erosion syndrome | definition of corneal erosion syndrome by Medical dictionary
Looking for online definition of corneal erosion syndrome in the Medical Dictionary? corneal erosion syndrome explanation free. What is corneal erosion syndrome? Meaning of corneal erosion syndrome medical term. What does corneal erosion syndrome mean?
http://medical-dictionary.thefreedictionary.com/corneal+erosion+syndrome
Scientists characterize proteome of human corneaScientists characterize proteome of human cornea
The results from this research may open the door to future therapeutics for a myriad of corneal disorders. It is essential to know the biochemical composition of normal healthy corneas in the effort to understand the molecular mechanisms behind corneal disorders, emphasizes Dr. Enghild. By comparative proteomic studies of diseased and normal corneas we can identify differences in the expression profiles that may suggest avenues for therapeutic interventions. Because the cornea is so accessible, the potential for developing effective drugs for the treatment of corneal diseases is good. Furthermore, the work is likely to improve the clinical classifications of corneal diseases. Identification of the protein profile of the normal human cornea may also be very useful in the effort toward generating artificial corneas for transplantation ...
http://www.innovations-report.com/html/reports/life-sciences/report-47353.html
Systematic review of differential methylation in rare ophthalmic diseases | BMJ Open OphthalmologySystematic review of differential methylation in rare ophthalmic diseases | BMJ Open Ophthalmology
Aberrant methylation was established as a pathogenic biomarker of ophthalmic disease in eight studies. This included: the identification of methylation as playing a role in the high mutability of exon 21 within KIF21A in CFEOM1,46 loss of H3K9me2-mediated repression in brittle cornea syndrome,42 differential methylation of autoinflammatory genes in retinopathy of prematurity (including NGPT1, BDNF, CRP, MPO, SAA1, SAA2, TNFRSF1A and TNFRSF1B),47 differential methylation of several genes corresponding to RNA sequencing gene expression analysis in keratoconus,50 hypomethylation in genes related to ion channel roles which are essential for corneal endothelium function in patients with FECD,44 differential miRNA expression in FECD cases compared with controls including the hypermethylation of miR-199b-5p which negatively regulates the corneal transcription factors Snail and ZEB1,54 altered histone methylation status associated with changes in TGFBIp expression levels in GCD243 and, finally, skewed ...
https://bmjophth.bmj.com/content/4/1/e000342
Corneal Disease Pensacola, Florida
Corneal Disease Pensacola, Florida - The Eye Institute at Medical Center specializes in Corneal Disease. Our practice serves Pensacola, Florida and surrounding areas.
http://mcceyeinstitute.com/eye-conditions/corneal-disease/
Favorie Articles of Tri-State Hemodynamic ServicesFavorie Articles of Tri-State Hemodynamic Services
Article in Press, EJCTS-6393; No of Pages 5 David Crane et al, Platelet Rich Plasma Matrix Grafts, Prctical Pain Management, Jan/Feb 2008 Lopez-Plandolit S, Morales MC, Freire V, Etxebarria J, Duran JA. Plasma rich in growth factors as a therapeutic agent for persistent corneal epithelial defects. Cornea. 2010 Aug;29(8):843-8.. Allio, Jorge L., Colecha, Jose R., Pastor, Silvia, Rodriguez, Alejandra, and Artola, Alberto. Symptomatic Dry Eye Treatment with Autologous Platelet-Rich Plasma. Opthalmic Res 2007;39:124-129.. Orthopedic - General. Muschler, G, et al, Age - and Gender - Related Changes in the Cellularity of Human Bone Marrow and the Prevalence of Osteoblastic Progenitors, Journal of Orthopaedic Research, 2001: 19;117-125. Romih, M, et al, The Vertebral Interbody Grafting Sites Low Concentration in Osteogenic Progenitors can Greatly Benefit from Addition of Illiac Crest Bone Marrow, European Spine Journal, 2005: 14;645-648.. Bodke, D, et al, Bone Grafts Prepared with Selective Cell ...
http://bloodrecycling.net/articles.html
Anatomy of Strength Training: The Five Essential Exercises by Pat Manocchia - MAGIX PICTURES Library
2. A Ocular surface reconstruction with allolimbal transplantation and use of two membranes. The inner 9-mm disc acts as a graft and the outer larger membrane as a patch. S. Dua). B The outer membrane has cut through sutures and retracted, exposing the inner membrane. e. 5 Clinical Studies and Outcomes (Definitions of Success and Grading of Disease Severity) A B membrane was intended as a patch and acted as such for the expected duration but the PED did not heal. When the above criteria were applied to 74 procedures involving use of the amniotic membrane, failure of the procedure was observed in 44 % of patients where the membrane was used in the presence of stem cell deficiency, in 33 % of procedures where the membrane was used in the absence of stem cell deficiency and in 44 % of patients where the membrane was used for conjunctival reconstruction. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. References 1. Anderson DF, Ellies P, Pires RT, Tseng SC (2001) Amniotic membrane transplantation for partial ...
http://magixfx.com/ebooks/anatomy-of-strength-training-the-five-essential-exercises
Additional file 1: of Transplantation of oral mucosal epithelial cells seeded on decellularized and lyophilized amniotic...Additional file 1: of Transplantation of oral mucosal epithelial cells seeded on decellularized and lyophilized amniotic...
Additional file 1: of Transplantation of oral mucosal epithelial cells seeded on decellularized and lyophilized amniotic membrane for the regeneration of injured endometrium
https://springernature.figshare.com/articles/Additional_file_1_of_Transplantation_of_oral_mucosal_epithelial_cells_seeded_on_decellularized_and_lyophilized_amniotic_membrane_for_the_regeneration_of_injured_endometrium/7879070/1
band keratopathy Disease Ontology Browser - DOID:11164band keratopathy Disease Ontology Browser - DOID:11164
There are currently no human or mouse genes associated with this disease in the MGI database. Synonyms: Band-shaped keratopathy
http://www.informatics.jax.org/disease/217500
Corneal diseases
The National Institute of Health has a webpage (https://nei.nih.gov/health/cornealdisease) which reviews the structure of the eyes outermost front layer, the cornea, and various diseases that can affect it. These common diseases include Corneal Infections, Dry Eye, Fuchs Dystrophy, Herpes Zoster (Shingles), Iridocorneal Endothelial Syndrome, Keratoconus, Lattice Dystrophy, Map-Dot-Fingerprint Dystrophy, Ocular Herpes, Pterygium, and Stevens-Johnson Syndrome. ...
http://1800myeyedoc.com/corneal-diseases.html
Tissue engg, stem cell therapy help reverse corneal blindness | Chennai News - Times of IndiaTissue engg, stem cell therapy help reverse corneal blindness | Chennai News - Times of India
Doctors at the Aravind Eye Hospital have used tissues from the inner cheek to reverse corneal blindness. The technique is called ex vivo expansion of
https://timesofindia.indiatimes.com/Chennai/Tissue_engg_stem_cell_therapy_help_reverse_corneal_blindness/articleshow/3859532.cms
Eye - Calcific band keratopathyEye - Calcific band keratopathy
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patients clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician ...
http://pathologyoutlines.com/topic/eyecorneacalcificbandkeratopathy.html
Clinical application of living-related conjunctival-limbal allograft<...
TY - JOUR. T1 - Clinical application of living-related conjunctival-limbal allograft. AU - Tsubota, Kazuo. AU - Shimmura, Shigeto. AU - Shinozaki, Naoshi. AU - Holland, Edward J.. AU - Shimazaki, Jun. PY - 2002. Y1 - 2002. N2 - PURPOSE: To report one successful case of conjunctival-limbal allograft for the treatment of a severe ocular surface disorder. METHODS: Interventional case report. A 9-year-old patient suffering from Stevens-Johnson syndrome with total keratinization of the ocular surface of both eyes was treated in the left eye by corneal and conjunctival stem cell transplantation. Oral cyclosporin A and topical autologous serum and corticosteroids were administered. RESULTS: Mucosal epithelial phenotype was maintained in the left eye at most recent examination for more than 3 years after ocular surface reconstruction. CONCLUSION: A total keratinized ocular surface may be treated with the combination of conjunctival and corneal stem cell transplantation.. AB - PURPOSE: To report one ...
https://keio.pure.elsevier.com/en/publications/clinical-application-of-living-related-conjunctival-limbal-allogr
Nasal/eye
The gel is a means of stimulating wound healing.. Treatment of noninflammatory diseases of the cornea of ​​the eye (keratopathy), z. Dystrophies of the cornea (eating disorders), degeneration of the cornea (regression), recurrent corneal erosion (Abschilferungen) and corneal injury (injury) in contact lens wearers.. An additional medicine to support the healing of damage to the cornea and conjunctiva, corrosion and burns.. An additional medicine for specific therapy of infectious corneal processes of bacterial, viral or mycogenous (caused by fungi) origin.. Note:. The gel is not suitable for the treatment of infectious corneal processes of bacterial, viral or mycotic origin, but only as an additional medicine for the specific therapy of these corneal diseases.. ...
https://pilzona.com/en/373-nasaleye
Anesthetic keratopathy presenting as bilateral Mooren-like ulcers | OPTHAnesthetic keratopathy presenting as bilateral Mooren-like ulcers | OPTH
Anesthetic keratopathy presenting as bilateral Mooren-like ulcers Hamid Khakshoor,1 Majid Moshirfar,2 Rachel G Simpson,3 Hamid Gharaee,1 Amir H Vejdani,1 Steven M Christiansen,2 Jason N Edmonds,2 Nicholas L Behunin21Mashhad University of Medical Sciences, Department of Ophthalmology, Mashad, Iran; 2John A Moran Eye Center, University of Utah, Salt Lake City, UT, 3The University of Arizona College of Medicine, Phoenix, AZ, USAAbstract: This observational case report describes the development of bilateral Mooren-like ulcers in a patient with anesthetic keratopathy. A 42-year-old man with a recent history of minor eye trauma and pain self-treated with tetracaine eye drops presented with complaints of acutely worsening vision and severe pain bilaterally. His visual acuity at presentation was limited to hand motion. Slit-lamp examination revealed bilateral epithelial defects at the center of the cornea, and an area of stromal infiltration and thinning with an undermining leading edge resembling a Mooren'
https://www.dovepress.com/anesthetic-keratopathy-presenting-as-bilateral-mooren-like-ulcers-peer-reviewed-article-OPTH
2012 ICD-9-CM Diagnosis Code 371.23 : Bullous keratopathy2012 ICD-9-CM Diagnosis Code 371.23 : Bullous keratopathy
Free, official information about 2012 (and also 2013-2015) ICD-9-CM diagnosis code 371.23, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
http://www.icd9data.com/2012/Volume1/320-389/360-379/371/371.23.htm
Corneal disease remains major cause of blindness | Ophthalmology TimesCorneal disease remains major cause of blindness | Ophthalmology Times
Washington, DC-Corneal pathology continues to be a major cause of blindness in developing countries of the world, and nearly all of the diseases and conditions leading to corneal blindness are preventable or treatable with existing knowledge and technology, said Gullapalli N. Rao, MD, at World Cornea Congress V.
https://www.ophthalmologytimes.com/view/corneal-disease-remains-major-cause-blindness
Corneal diseases in horses (Proceedings)
The cornea is the front layer of the fibrous tunic of the eye; it is composed of three distinct layers and one distinct membrane. The outer epithelial layer is approximately five to ten cells thick. The middle stromal layer comprises about 95% of the cornea, and the inside layer is the endothelial layer, and its basement membrane is Descemets membrane.
http://veterinarycalendar.dvm360.com/corneal-diseases-horses-proceedings
Sudden bilateral corneal oedema in a patient with Parkinsons disease<...Sudden bilateral corneal oedema in a patient with Parkinsons disease<...
TY - JOUR. T1 - Sudden bilateral corneal oedema in a patient with Parkinsons disease. AU - Park, Choul Yong. AU - Chuck, Roy S.. PY - 2011/3/1. Y1 - 2011/3/1. UR - http://www.scopus.com/inward/record.url?scp=79952216563&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=79952216563&partnerID=8YFLogxK. U2 - 10.1111/j.1755-3768.2009.01561.x. DO - 10.1111/j.1755-3768.2009.01561.x. M3 - Article. C2 - 19604157. AN - SCOPUS:79952216563. VL - 89. SP - 198. EP - 199. JO - Acta Ophthalmologica. JF - Acta Ophthalmologica. SN - 1755-375X. IS - 2. ER - ...
https://einstein.pure.elsevier.com/en/publications/sudden-bilateral-corneal-oedema-in-a-patient-with-parkinsons-dise-2
Mimicking Ocular Development and Treating Corneal Blindness using iPSCs | Stem Cells PortalMimicking Ocular Development and Treating Corneal Blindness using iPSCs | Stem Cells Portal
Researchers describe how multilayered ocular structures generated from iPSCs may provide a patient-specific means to treat forms of blindness
https://stemcellsportal.com/article-scans/mimicking-ocular-development-and-treating-corneal-blindness-using-ipscs
International Journal of Keratoconus and Ectatic Corneal DiseasesInternational Journal of Keratoconus and Ectatic Corneal Diseases
The mean LogMAR DCVA was 0.32 (~20/42) ±0.27 [range: −0.10 (20/15) to 1.30 (20/400)]. There were strong correlations between DCVA and many keratometric, topometric and tomographic indices. A strong positive correlation was found between DCVA and BAD-Df (ρ = 0.648, p , 0.001), BAD-Db (ρ = 0.633, p , 0.001), K2 (ρ = 0.643, p , 0.001), Kmax (ρ = 0.608, p , 0.001), TKC (ρ = 0.558, p , 0.001), BAD-D (ρ = 0.577, p , 0.001), ISV (ρ = 0.573, p , 0.001), CKI (ρ = 0.530, p , 0.001), KI (ρ = 0.531, p , 0.001). A strong negative correlation was seen between DCVA and Asph Q front 30° (ρ = −0.521, p , 0.001). ...
https://www.ijkecd.com/abstractArticleContentBrowse/IJKECD/21/1/3/1957/abstractArticle/Article
North Shore Eye Health And Wellness - Optometry In Cedarburg, WI USA :: Dry Eye and Corneal DiseaseNorth Shore Eye Health And Wellness - Optometry In Cedarburg, WI USA :: Dry Eye and Corneal Disease
North Shore Eye Health and Wellness is your local optometrist in Cedarburg serving all of your vision care needs. Call us today at 262-421-4412 for an appointment.
http://www.northshore-eye.com/eye-health-services/specialty-contact-lenses/dry-eye-and-corneal-disease
Future Of Gene Therapy For Corneal Diseases Causing Blindness - Eye BulletinFuture Of Gene Therapy For Corneal Diseases Causing Blindness - Eye Bulletin
Cornea is an important part of the eye required for clear vision. Even microscopic changes in cornea can cause moderate to severe reduction in vision. These
https://eyebulletin.com/future-of-gene-therapy-for-corneal-diseases-causing-blindness/
Corneal Disease Permanent Solution With Vitamin BCorneal Disease Permanent Solution With Vitamin B
Patients in the United States who have the cornea-damaging disease keratoconus may soon be able to benefit from a new treatment that is already proving
http://www.medindia.net/news/Corneal-Disease-Permanent-Solution-With-Vitamin-B-92569-1.htm
Climatic keratopathy definition | Drugs.comClimatic keratopathy definition | Drugs.com
Definition of climatic keratopathy. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
https://www.drugs.com/dict/climatic-keratopathy.html
Tarsorrhaphy in aluva | Corneal Disease Surgery in Kochi - Dr Tony Fernandez Eye hospitalTarsorrhaphy in aluva | Corneal Disease Surgery in Kochi - Dr Tony Fernandez Eye hospital
Tarsorrhaphy is mainly used for eyelid closure procedure. Know more about the treatments, surgery, care taken after surgery. Visit our website.
https://www.drtonyseyehospital.com/eye-speciality/orbit-oculpplasty/tarsorrhaphy
Res, Tide 5mg Tab 10`s additionRes, Tide 5mg Tab 10`s addition
Band keratopathy is Tie. 5. 13C NMR assignments for sodium valproate ппAssignments at carbon number 1 2 3 4 5 Chemical shift, d,(ppm relative to TMS) 186. 6 2.
http://tovopt.ru/ed-pill-shop/tide-5mg-tab-10s.html
FAQs on Corneal Diseases - Micro Chirurgia OculareFAQs on Corneal Diseases - Micro Chirurgia Oculare
Cornea relate question could be a lot more than the ones above: Dr. Badalà is at your disposal to answer to your questions, carefully evaluating each and every case. The only thing youre left to do is get in touch or book an appointment in Milan, Rome or Catania: start your path to recovery in a safe way. Its always best to gather information from reliable sources such as a professional ophthalmologist or a certified center with significant experience on the field.. ...
https://www.microchirurgiaoculare.com/en/eye-conditions/corneal-diseases/faqs-on-corneal-diseases/
Florida keratopathyFlorida keratopathy
"Corneal Diseases in Cats". Proceedings of the 30th World Congress of the World Small Animal Veterinary Association. Retrieved ... CS1 errors: generic name, Dog diseases, Cat diseases). ... The disease may be induced by repeated stings to the eyes by ... The disease is found in the southeastern parts of the United States. In other parts of the world it is confined to tropics and ...
https://en.wikipedia.org/wiki/Florida_keratopathy
Santosh G. HonavarSantosh G. Honavar
"Diagnostic tests for corneal diseases". Indian J Ophthalmol. 42 (2): 89-99. PMID 7927639.{{cite journal}}: CS1 maint: multiple ... Retinoblastoma protein Coats' disease Trilateral retinoblastoma Pinealoblastoma India portal Medicine portal Long link - please ... "Rosai dorfman disease of the orbit". J Hematol Oncol. 1: 7. doi:10.1186/1756-8722-1-7. PMC 2474646. PMID 18588698.{{cite ... adjuvant therapy to mitigate the high risk of metastasis and multimodal management of orbital affection of the disease and he ...
https://en.wikipedia.org/wiki/Santosh_G._Honavar
Corneal dystrophies in dogsCorneal dystrophies in dogs
Corneal dystrophies are a group of diseases that affect the cornea in dogs. Corneal dystrophy in dogs usually does not cause ... The disease is similar to Fuchs' dystrophy in humans. Many breeds are affected by corneal dystrophy with many different ... Sapienza, John S. (2002). "Corneal Diseases of Dogs and Cats". Proceedings of the 27th World Congress of the World Small Animal ... Esson, DW (2015). "Chapter 54: Corneal dystrophy". Clinical Atlas of Canine and Feline Ophthalmic Disease. John Wiley & Sons. p ...
https://en.wikipedia.org/wiki/Corneal_dystrophies_in_dogs
Chronic superficial keratitisChronic superficial keratitis
Sapienza, John S. (2002). "Corneal Diseases of Dogs and Cats". Proceedings of the 27th World Congress of the World Small Animal ... Ultraviolet light is important in the genesis of the disease which is seen at higher prevalence at elevated altitude and has a ... Chronic superficial keratitis (CSK), also known as pannus or Uberreiter's disease, is an inflammatory condition of the cornea ...
https://en.wikipedia.org/wiki/Chronic_superficial_keratitis
MalondialdehydeMalondialdehyde
"Evidence of oxidative stress in human corneal diseases". J. Histochem. Cytochem. 50 (3): 341-51. doi:10.1177/002215540205000306 ...
https://en.wikipedia.org/wiki/Malondialdehyde
NitrotyrosineNitrotyrosine
"Evidence of oxidative stress in human corneal diseases". The Journal of Histochemistry and Cytochemistry. 50 (3): 341-351. doi: ... Generally in many disease states, oxidative stress increases the production of superoxide (O2−) and NO forming peroxynitrite ( ... Nitrotyrosine is also found in numerous other disease-affected tissues, such as the cornea in keratoconus. Peroxynitrite and/or ... Increased level of nitrotyrosine is detected in rheumatoid arthritis, septic shock and coeliac disease. In all these studies ...
https://en.wikipedia.org/wiki/Nitrotyrosine
Lecithin-cholesterol acyltransferaseLecithin-cholesterol acyltransferase
Cogan DG, Kruth HS, Datilis MB, Martin N (1993). "Corneal opacity in LCAT disease". Cornea. 11 (6): 595-9. doi:10.1097/00003226 ... LCAT deficiency can cause impaired vision due to cholesterol corneal opacities, anemia, and kidney damage. It belongs to the ... 1991). "A molecular defect causing fish eye disease: an amino acid exchange in lecithin-cholesterol acyltransferase (LCAT) ... cholesterol acyl transferase and its use to analyse the genes in patients with LCAT deficiency and fish eye disease". Biochem. ...
https://en.wikipedia.org/wiki/Lecithin–cholesterol_acyltransferase
A. Edward MaumeneeA. Edward Maumenee
... discovery of new diseases, such as congenital corneal dystrophies; and enhanced methods of surgery for cataract, corneal ... These achievements include the following: initial description of the immunological nature of corneal graft rejection; ... macular degeneration and glaucoma and was a leading surgeon for corneal transplants and cataracts. Maumenee received his A.B ... was an American ophthalmologist who pioneered treatments for retinal diseases, ...
https://en.wikipedia.org/wiki/A._Edward_Maumenee
Network of Excellence for Functional BiomaterialsNetwork of Excellence for Functional Biomaterials
Corneal diseases are the major cause of vision loss worldwide. Every year approximately 10,000,000 people are affected by ... various eye disorders and require corneal transplantation. Tissue grafts, including amniotic membranes, constitute the gold ...
https://en.wikipedia.org/wiki/Network_of_Excellence_for_Functional_Biomaterials
Corneal neovascularizationCorneal neovascularization
... while deep presentations may be caused by chronic inflammatory and anterior segment ocular diseases. Corneal neovascularization ... Maintaining avascularity of the corneal stroma is an important aspect of corneal pathophysiology as it is required for corneal ... Corneal neovascularization (CNV) is the in-growth of new blood vessels from the pericorneal plexus into avascular corneal ... A decrease in corneal transparency causes visual acuity deterioration. Corneal tissue is avascular in nature and the presence ...
https://en.wikipedia.org/wiki/Corneal_neovascularization
Corneal cross-linkingCorneal cross-linking
"Facts About the Cornea and Corneal Disease". NEI. May 2016. Archived from the original on 22 November 2016. Retrieved 6 ... Corneal cross-linking with riboflavin (vitamin B2) and UV-A light is a surgical treatment for corneal ectasia such as ... Corneal Collagen Cross-Linking on National Keratoconus Foundation website. Corneal Collagen Cross-Linking on EyeWiki from the ... "Corneal collagen crosslinking: A clinical update". "Corneal cross-linking" (PDF). Moorfields Eye Hospital NHS Foundation Trust ...
https://en.wikipedia.org/wiki/Corneal_cross-linking
Corneal dystrophyCorneal dystrophy
Fabry disease, cystinosis, tyrosine transaminase deficiency, systemic lysosomal storage diseases, and several skin diseases (X- ... of lattice corneal dystrophy Granular corneal dystrophy, type 1 Granular corneal dystrophy, type 2 Macular corneal dystrophy ... Lattice corneal dystrophy Granular corneal dystrophy Macular corneal dystrophy Schnyder crystalline corneal dystrophy ... Recurrent corneal erosion Keratoconus Keratoglobus Corneal dystrophies in dogs Dyskeratosis corneal and photophobia in XLPDR ...
https://en.wikipedia.org/wiki/Corneal_dystrophy
Pterygium (eye)Pterygium (eye)
"Facts About the Cornea and Corneal Disease , National Eye Institute". The National Eye Institute (NEI). May 2016. Archived from ... Other conditions that can look similar include a pinguecula, tumor, or Terrien's marginal corneal degeneration. Prevention may ... Myron, Yanoff; Jay S., Duker (2019). "Cornea and ocular surface diseases". Ophthalmology (5th ed.). Edinburgh: Elsevier. p. 310 ... however corneal topography is a practical test (technique) as the condition worsens. Pterygium should be differentiated from ...
https://en.wikipedia.org/wiki/Pterygium_(eye)
Corneal ulcers in animalsCorneal ulcers in animals
Immune-mediated eye disease can cause ulcers at the border of the cornea and sclera. Corneal ulcers are painful due to nerve ... Corneal ulcers are one of the most common eye diseases in dogs. They are caused by trauma, detergent burns, and infections. ... Corneal ulcers in cats can be caused by trauma, detergent burns, infections, and other eye diseases. One common cause not seen ... Corneal ulceration is a very common disease of the equine eye and can have sight-threatening consequences. Aggressive treatment ...
https://en.wikipedia.org/wiki/Corneal_ulcers_in_animals
Spastic ataxia-corneal dystrophy syndromeSpastic ataxia-corneal dystrophy syndrome
that the disease is different from a disease known as corneal-cerebellar syndrome that had been found in 1985. Symptoms include ... Spastic ataxia-corneal dystrophy syndrome (also known as Bedouin spastic ataxia syndrome) is an autosomally resessive disease. ... Rare disease "Orphanet: Spastic ataxia-corneal dystrophy syndrome". Orphanet. October 2006. Retrieved 18 May 2016. "OMIM Entry ... A member of the family who was first diagnosed with this disease also had Bartter syndrome. It was concluded by its first ...
https://en.wikipedia.org/wiki/Spastic_ataxia-corneal_dystrophy_syndrome
Corneal-cerebellar syndromeCorneal-cerebellar syndrome
that the disease is different from a disease known as spastic ataxia-corneal dystrophy syndrome that had been found a year ... Corneal dystrophy is also epithelian instead of being stromal. Medicine portal Rare disease "Orphanet: Corneal cerebellar ... Corneal-cerebellar syndrome (also known as Der Kaloustian-Jarudi-Khoury syndrome) is an autosomally recessive disease that was ... Corneal-cerebellar syndrome differs from the spastic ataxia-corneal dystrophy syndrome by causing intellectual disability. ...
https://en.wikipedia.org/wiki/Corneal-cerebellar_syndrome
Corneal buttonCorneal button
Diseases likely to be transmissible via corneal transplantations include HIV, Herpes simplex virus and Prion disease. There are ... Diseases transmissible via corneal transplantation include bacterial infection and fungal infection, rabies, Hepatitis B and ... Corneal buttons cannot be reliably frozen as a storage method. Usually, the corneal button is removed from the entire globe ... The corneal cells are also injected with dehydrating macromolecules to maintain hydration, this causes the corneal button to ...
https://en.wikipedia.org/wiki/Corneal_button
Corneal transplantationCorneal transplantation
Infectious disease transmission through corneal transplantation is exceedingly rare. All corneal grafts are screened for the ... Facts About the Cornea and Corneal Disease The National Eye Institute (NEI) (CS1 maint: archived copy as title, Webarchive ... This technique is used in cases of anterior corneal opacifications, scars, and ectatic diseases such as keratoconus. ... Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced ...
https://en.wikipedia.org/wiki/Corneal_transplantation
Labrador RetrieverLabrador Retriever
Eye diseases may include progressive retinal atrophy, cataracts, corneal dystrophy and retinal dysplasia. They can suffer from ... A form of Parkinson's disease confined the former president to a wheelchair or motorised scooter in the final years of his life ...
https://en.wikipedia.org/wiki/Labrador_Retriever
PannusPannus
... may also develop in diseases of the corneal stem cells, such as aniridia. It is often resolved by peritomy. Farlex ... From Autoimmunity and Disease by Harley Y. Tse and Michail K. Shaw: Chronic stages of the disease typically coincide with the ... Chronic local hypoxia (such as that occurring with overuse of contact lenses) or inflammation may lead to peripheral corneal ... In people suffering from rheumatoid arthritis, pannus tissue eventually forms in the joint affected by the disease, causing ...
https://en.wikipedia.org/wiki/Pannus
IchthyosisIchthyosis
There can be ocular manifestations of ichthyosis, such as corneal and ocular surface diseases. Vascularizing keratitis, which ... Ichthyosis is a genetically and phenotypically heterogeneous disease that can be isolated and restricted to the skin ... European Network for Ichthyosis - International patients network run by national European patients associations Skin disease ... DermAtlas 1896838546 Ichthyosis Overview - US National Institute of Arthritis and Musculoskeletal and Skin Diseases (Articles ...
https://en.wikipedia.org/wiki/Ichthyosis
Hunter syndromeHunter syndrome
Unlike MPS I, corneal clouding is not associated with this disease. Hunter syndrome may present with a wide variety of ... For those with milder forms of the disease, a wider variety of outcomes exist. Many live into their 20s and 30s, but some may ... 2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. p. 544. ISBN 978-0-7216-2921-6. Le, Tao; Bhushan ... DNA sequencing can reveal if someone is a carrier for the disease. Because of the wide variety of phenotypes, the treatment for ...
https://en.wikipedia.org/wiki/Hunter_syndrome
List of dog diseasesList of dog diseases
Corneal diseases Corneal dystrophy is a condition characterized by bilateral, noninflammatory opacity of the cornea. It appears ... This list of dog diseases is a selection of diseases and other conditions found in the dog. Some of these diseases are unique ... The disease in dogs is usually nodular skin lesions of the head and trunk. Aspergillosis* is a fungal disease that in dogs is ... Lyme disease* is a disease caused by Borrelia burgdorferi, a spirochaete, and spread by ticks of the genus Ixodes. Symptoms in ...
https://en.wikipedia.org/wiki/List_of_dog_diseases
Peter SzurmanPeter Szurman
"THE REVOLUTIONARY SYSTEM FOR THE THERAPY OF ENDOTHELIAL CORNEAL DISEASES : THE NEW DMEK CARTRIDGE" (PDF). Geuder.de. Retrieved ... corneal transplantation with laser and partial grafts (DMEK), stem cell therapy for corneal surface healing disorders after ... biotechnological research of new drugs and tamponades for retinal diseases as well as electronic visual prostheses for corneal ... These include international patent grants on the first implantation system for corneal partial grafts, a transplant cartridge ...
https://en.wikipedia.org/wiki/Peter_Szurman
Iridocorneal endothelial syndromeIridocorneal endothelial syndrome
Facts About the Cornea and Corneal Disease The National Eye Institute (NEI). (Articles with short description, Short ... On exam patients have normal to decreased visual acuity, and a "beaten metal appearance" of the corneal endothelium, corneal ... of diseases characterized by slowly progressive abnormalities of the corneal endothelium and features including corneal edema, ... The disease is chronic and often progresses slowly. Prognosis is generally poor when associated with glaucoma. Friedman, Neil J ...
https://en.wikipedia.org/wiki/Iridocorneal_endothelial_syndrome
Ali Asghar KhodadoustAli Asghar Khodadoust
His medical reputation was the result of his extensive studies on corneal diseases and transplantation biology. Khodadoust died ... was an Iranian eye surgeon specializing in corneal transplantation, in whose honor the Khodadoust rejection line is named. He ...
https://en.wikipedia.org/wiki/Ali_Asghar_Khodadoust
Lecithin cholesterol acyltransferase deficiencyLecithin cholesterol acyltransferase deficiency
Fish-eye disease is less severe and most commonly presents with impaired vision due to corneal opacification. It rarely ... The disease has two forms: Familial LCAT deficiency, in which there is complete LCAT deficiency, and Fish-eye disease, in which ... Both diseases are very rare with ~70 reported cases of familial LCAT deficiency and ~30 cases of fish-eye disease. CBC: ... "Fish-eye disease , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". rarediseases.info.nih.gov. ...
https://en.wikipedia.org/wiki/Lecithin_cholesterol_acyltransferase_deficiency
Nucleotide sugarNucleotide sugar
... is a congenital disease resulted from altered function of UDP-GlcNAc epimerase . Macular corneal dystrophy: is a congenital ... Any malfunction in any contributing enzyme will lead to a certain disease for example: Inclusion body myopathy: ... disease resulted from malfunction of GlcNAc-6-sulfotransferase. Congenital disorder in α-1,3 mannosyl transferase will result ...
https://en.wikipedia.org/wiki/Nucleotide_sugar
Corneal dystrophy-perceptive deafness syndromeCorneal dystrophy-perceptive deafness syndrome
"Corneal dystrophy and perceptive deafness - About the Disease - Genetic and Rare Diseases Information Center". rarediseases. ... Corneal dystrophy Sensorineural hearing loss "Corneal dystrophy and perceptive deafness". "Corneal Dystrophy and Perceptive ... "corneal dystrophy and sensorineural deafness , Hereditary Ocular Diseases". disorders.eyes.arizona.edu. Retrieved 2022-08-03. ... Corneal dystrophy-perceptive deafness syndrome, also known as Harboyan syndrome, is a rare genetic disorder characterized by ...
https://en.wikipedia.org/wiki/Corneal_dystrophy-perceptive_deafness_syndrome
Keratoendotheliitis fugax hereditariaKeratoendotheliitis fugax hereditaria
A clinical and specular microscopic study of a family with dominant inflammatory corneal disease". Acta Ophthalmol (Copenh). 65 ... to central corneal stromal opacities. Approximately 50 known cases have been reported in the literature. The disease so far has ... a Finnish ophthalmologist with an interest in hereditary eye diseases. He reported this disease as keratitis fugax hereditaria ... dark patches in the corneal endothelium, thought to represent patchy corneal endothelial swelling. The endothelium appears ...
https://en.wikipedia.org/wiki/Keratoendotheliitis_fugax_hereditaria
Roberts syndromeRoberts syndrome
John Bingham Roberts (1852-1924) of Philadelphia, who reported the disease characteristics in 1919. Roberts reported a disease ... a protruding eyeball Corneal clouding- clouding of the front-most part of the eye Hypoplastic nasal alae- narrowing of the ... Carriers for the disorder are heterozygotes due to the autosomal recessive nature of the disease. Carriers are also not at risk ... The prognosis of the disease depends on the malformations, as the severity of the malformations correlates with survival. The ...
https://en.wikipedia.org/wiki/Roberts_syndrome
List of diseases (C)List of diseases (C)
Corneal anesthesia deafness mental retardation Corneal cerebellar syndrome Corneal crystals myopathy neuropathy Corneal ... Marie-Tooth disease type 1A Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease type 1C Charcot-Marie-Tooth disease ... Marie-Tooth disease type 2C Charcot-Marie-Tooth disease type 2D Charcot-Marie-Tooth disease type 4A Charcot-Marie-Tooth disease ... Tooth disease Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease deafness dominant type Charcot-Marie-Tooth disease ...
https://en.wikipedia.org/wiki/List_of_diseases_(C)
Neonatal conjunctivitisNeonatal conjunctivitis
Eye diseases, Disorders of conjunctiva, Herpes simplex virus-associated diseases, Neonatology, Chlamydia infections, Gonorrhea) ... Untreated cases may develop corneal ulceration, which may perforate, resulting in corneal opacification and staphyloma ... List of systemic diseases with ocular manifestations "Conjunctivitis, Neonatal: Overview". eMedicine. 2019-05-30. Tan, Aik-Kah ... "Chlamydia trachomatis". In: Red Book: 2015 Report of the Committee on Infectious Diseases, 30th, Kimberlin DW (Ed), Elk Grove ...
https://en.wikipedia.org/wiki/Neonatal_conjunctivitis
StaphylomaStaphyloma
Defective vision occurs due to marked corneal astigmatism. Treatment consists of localised staphylectomy under heavy doses of ... Articles lacking sources from January 2013, All articles lacking sources, Eye diseases). ... following healing of a perforating injury or a peripheral corneal ulcer. There may be associated secondary angle closure ...
https://en.wikipedia.org/wiki/Staphyloma
Phlyctenular keratoconjunctivitisPhlyctenular keratoconjunctivitis
Clinical findings of Corneal lesion or corneal ulceration. The symptoms of phlyctenular keratoconjunctivitis are primarily ... Articles with short description, Short description is different from Wikidata, Eye diseases). ... Corneal lesions are usually triangular in shape, with the base at the limbus and the apex pointing towards the center of the ... Artificial tears can reduce dryness and discomfort from corneal lesions. Photophobic discomfort can be mitigated with dark ...
https://en.wikipedia.org/wiki/Phlyctenular_keratoconjunctivitis
Bullous keratopathyBullous keratopathy
Eye diseases, All stub articles, Disease stubs, Eye stubs). ... The corneal endothelial cells normally do not undergo mitotic ... Disease begins with vesicles that coalesce. There is severe progressing edema and rupture may occur in 24 hours or less. ... "Descemet's membrane endothelial keratoplasty versus Descemet's stripping automated endothelial keratoplasty for corneal ...
https://en.wikipedia.org/wiki/Bullous_keratopathy
Iridogoniodysgenesis, dominant typeIridogoniodysgenesis, dominant type
... refers to a spectrum of diseases characterized by malformations of the irido-corneal angle of the anterior chamber of the eye. ... Rare diseases, Eye diseases, Congenital disorders of eyes). ... "rare disease" by the Office of Rare Diseases (ORD). This means ... These cells lead to formation of most of the anterior segment structures of the eye (corneal stroma & endothelium, iris stroma ... March 2004 Iridogoniodysgenesis, dominant type at NIH's Office of Rare Diseases Berg, Fredrik (1932-12-01). "Erbliches ...
https://en.wikipedia.org/wiki/Iridogoniodysgenesis,_dominant_type
Afghan HoundAfghan Hound
Ocular conditions that can occur include medial canthal pocket syndrome (breed predisposition due to shape of head), corneal ... Gough, Thomas (2008). Breed predispositions to disease in dogs and cats. Oxford, UK: Wiley. pp. 11-12. ISBN 9780470690802. OCLC ...
https://en.wikipedia.org/wiki/Afghan_Hound
Human T-lymphotropic virus 1Human T-lymphotropic virus 1
Valproic acid has been studied to determine if it might slow the progression of HTLV disease by reducing viral load. Although ... One case report describes an HTLV-1 infected woman who developed chronic refractory eczema, corneal injury and adult T cell ... Individuals infected with HTLV-1 are at risk for opportunistic infections-diseases not caused by the virus itself, but by ... HTLV-1 is also associated with a progressive demyelinating upper motor neuron disease known as HTLV-1 associated myelopathy/ ...
https://en.wikipedia.org/wiki/Human_T-lymphotropic_virus_1
WhaleWhale
They also have glands on the eyelids and outer corneal layer that act as protection for the cornea. The olfactory lobes are ... These pollutants can cause gastrointestinal cancers and greater vulnerability to infectious diseases. They can also be poisoned ...
https://en.wikipedia.org/wiki/Whale
Peripheral neuropathyPeripheral neuropathy
... corneal neuropathy - 20 to 55% of people). Genetic diseases: Friedreich's ataxia, Fabry disease, Charcot-Marie-Tooth disease, ... Immune-mediated diseases, such as rheumatoid arthritis, systemic lupus erythematosus (SLE) Infections: leprosy, lyme disease, ... Wood-allum, Clare A.; Shaw, Pamela J. (2014). "Thyroid disease and the nervous system". Neurologic Aspects of Systemic Disease ... immune system disease, celiac disease, non-celiac gluten sensitivity, or viral infection. It can also be genetic (present from ...
https://en.wikipedia.org/wiki/Peripheral_neuropathy
Eye diseaseEye disease
Corneal neovascularization (H18.5) Fuchs' dystrophy - cloudy morning vision (H18.6) Keratoconus - degenerative disease: the ... Corneal ulcer / Corneal abrasion - loss of the surface epithelial layer of the eye's cornea (H16.1) Snow blindness / Arc eye - ... International Statistical Classification of Diseases (WHO ICD-10) - Diseases of the eye and adnexa (ICD-10 codes H00-H59) ... This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known ...
https://en.wikipedia.org/wiki/Eye_disease
1934 in science1934 in science
Tudor Thomas' work on corneal grafting restores the sight of a man who had been nearly blind for 27 years. April 3 - Percy Shaw ... of the behavior of exhaled respiratory droplets and their influence on the transmission of infectious respiratory diseases. ...
https://en.wikipedia.org/wiki/1934_in_science
GlaucomaGlaucoma
... though it occurs later in the course of the disease. As all methods of tonometry are sensitive to corneal thickness, methods ... Sometimes, the disease appears very rapidly, especially after cataract surgery procedures. A new treatment for this disease, as ... Glaucoma is a group of eye diseases that result in damage to the optic nerve (or retina) and cause vision loss. The most common ... Also, the corneal appearance is not as hazy. A reduction in visual acuity can occur followed neuroretinal breakdown. Associated ...
https://en.wikipedia.org/wiki/Glaucoma
Turmeric juiceTurmeric juice
... drops have been used in attempts to treat eye diseases that include pink eye, glaucoma, corneal ulcers and ... or mechanism of action to require rational use of it in treatment of human diseases. Turmeric grows wild in the forests of ...
https://en.wikipedia.org/wiki/Turmeric_juice
Biomolecular condensateBiomolecular condensate
August 2015). "A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation". Cell. 162 (5): 1066- ... Lewy bodies Stress granule P-body Germline P-granules - oskar Starch granules Glycogen granules Frodosomes (Dact1) Corneal lens ... Y. Shin and C. P. Brangwynne, "Liquid phase condensation in cell physiology and disease," Science, vol. 357, Sep 2017. Methods ... Aguzzi A, Altmeyer M (July 2016). "Phase Separation: Linking Cellular Compartmentalization to Disease". Trends in Cell Biology ...
https://en.wikipedia.org/wiki/Biomolecular_condensate
Keratic precipitateKeratic precipitate
... (KP) is an inflammatory cellular deposit seen on corneal endothelium. Acute KPs are white and round in ... They are indicative of inflammatory disease. Mutton fat KPs are due to granulomatous iridocyclitis. Another variant called red ... Tandon, Radhika (2014). Parson's Diseases of the Eye - E-Book. Elsevier Health Sciences. p. 616. ISBN 9788131238196. Retrieved ... KPs may be seen in hemorrhagic uveitis.[citation needed] Brightbill, Frederick S. (2009). Corneal Surgery: Theory, Technique ...
https://en.wikipedia.org/wiki/Keratic_precipitate
Feline viral rhinotracheitisFeline viral rhinotracheitis
Causing one-half of the respiratory diseases in cats, FVR is the most important of these diseases and is found worldwide. The ... FHV-1 also has a predilection for corneal epithelium, resulting in corneal ulcers, often pinpoint or dendritic in shape. Other ... In chronic nasal and sinus disease of cats, FHV-1 may play more of an initiating role than an ongoing cause. Infection at an ... Feline Upper Respiratory Disease from The Pet Health Library (Wikipedia articles needing page number citations from March 2012 ...
https://en.wikipedia.org/wiki/Feline_viral_rhinotracheitis
Rabies in popular cultureRabies in popular culture
Instead, the woman becomes a parasitic monster whose victims transform into rabid zombies whose bites spread the disease. Paris ... a dog-bite patient is suspected to be suffering from rabies contracted through a corneal transplant performed in Algeria, ... told a story about a taxidermist who contracts the disease from an infected squirrel. The Beavis and Butt-Head episode "Rabies ... the character Ramu dies of the disease. Yuriy Shcherbak's documentary novel Prychyny i naslidky (1986; in English: Causes and ...
https://en.wikipedia.org/wiki/Rabies_in_popular_culture
Pedram HamrahPedram Hamrah
"Corneal immunity is mediated by heterogeneous population of antigen‐presenting cells." Journal of Leukocyte Biology 74, no. 2 ( ... He was a faculty member in the laboratory of Ulrich von Andrian at Harvard's Immune Disease Institute from 2008 to 2012. Hamrah ... "The corneal stroma is endowed with a significant number of resident dendritic cells." Investigative Ophthalmology & Visual ... Hamrah P, Liu Y, Zhang Q, Dana MR (February 2003). "The corneal stroma is endowed with a significant number of resident ...
https://en.wikipedia.org/wiki/Pedram_Hamrah
Gertrud HurlerGertrud Hurler
... , née Zach (1 September 1889 - 1965), was a German pediatrician who wrote up a disease that came to be known as ... she observed two infants that displayed symptoms of corneal clouding, dwarfing skeletal dysplasia, spinal misalignment, and ... Previously known as gargoylism or lipochondrodystrophy, the disease was named after her, despite the initial report being given ...
https://en.wikipedia.org/wiki/Gertrud_Hurler
FluoresceinFluorescein
... where topical fluorescein is used in the diagnosis of corneal abrasions, corneal ulcers and herpetic corneal infections. It is ... is used in fluorescein angiography in research and to diagnose and categorize vascular disorders including retinal disease, ...
https://en.wikipedia.org/wiki/Fluorescein
Blister agentBlister agent
Center for Disease Control Archived January 22, 2005, at the Wayback Machine Cantharidin and Meloids: a review of classical ... corneal damage Mild respiratory distress to marked airway damage All blister agents currently known are denser than air, and ...
https://en.wikipedia.org/wiki/Blister_agent
EndophthalmitisEndophthalmitis
Corneal ulcer Orbital cellulitis Impairment of vision Complete loss of vision Loss of eye architecture Enucleation Bacteria: N ... Eye diseases, Medical emergencies). ...
https://en.wikipedia.org/wiki/Endophthalmitis
Winchester syndromeWinchester syndrome
This has led to the belief that there are many similar diseases within this family of mutations. As of 2007, it was found that ... corneal opacities) which can cause problems with vision. Winchester syndrome is believed to be inherited through autosomal ... Genetic counseling is typically prescribed for families to help aid in the understanding of the disease. There are a few ... It has been reported that several affected individuals have lived to middle age; however, the disease is progressive and ...
https://en.wikipedia.org/wiki/Winchester_syndrome
PhotophobiaPhotophobia
... or severe ophthalmologic diseases such as uveitis or corneal abrasion. A more extensive list follows: Causes of photophobia ... abnormalities of the eye Viral conjunctivitis Corneal abrasion Corneal dystrophy Corneal ulcer Disruption of the corneal ... such as that caused by a corneal foreign body or keratitis Ectopia lentis Endophthalmitis Eye trauma caused by disease, injury ... Too much light can enter the eye if it is damaged, such as with corneal abrasion and retinal damage, or if its pupil(s) is ...
https://en.wikipedia.org/wiki/Photophobia
UveitisUveitis
... disease inflammatory bowel disease Whipple's disease systemic lupus erythematosus polyarteritis nodosa Kawasaki's disease ... Prior to the administration of corticosteroids, corneal ulcers must be ruled out. This is typically done using a fluorescence ... Sympathetic ophthalmia Behçet disease Crohn's disease Fuchs heterochromic iridocyclitis Granulomatosis with polyangiitis HLA- ... Presence of this type of HLA allele has a relative risk of evolving this disease by approximately 15%. The most common form of ...
https://en.wikipedia.org/wiki/Uveitis
DistichiaDistichia
It can cause intense pain and corneal ulcers. Treatment is surgery or cryotherapy. Trichiasis Lymphedema distichiasis Brooks, ... Articles with short description, Short description is different from Wikidata, Dog diseases, Congenital disorders of eyes). ... corneal ulcers and scarring. Treatment options include manual removal, electrolysis, electrocautery, CO2 laser ablation, ...
https://en.wikipedia.org/wiki/Distichia
Corneal Disease | Cornea | MedlinePlusCorneal Disease | Cornea | MedlinePlus
ClinicalTrials.gov: Corneal Diseases (National Institutes of Health) * ClinicalTrials.gov: Corneal Injuries (National ... Treatments of corneal disorders include medicines, corneal transplantation, and corneal laser surgery. ... Corneal transplant (Medical Encyclopedia) Also in Spanish * Corneal ulcers and infections (Medical Encyclopedia) Also in ... Congenital stromal corneal dystrophy: MedlinePlus Genetics (National Library of Medicine) * Fish-eye disease: MedlinePlus ...
https://medlineplus.gov/cornealdisorders.html
Infectious corneal ulceration: a proposal for neglected tropical disease statusInfectious corneal ulceration: a proposal for neglected tropical disease status
2019)‎. Infectious corneal ulceration: a proposal for neglected tropical disease status. Bulletin of the World Health ...
https://apps.who.int/iris/handle/10665/330130?locale-attribute=es&
Infectious corneal ulceration: a proposal for neglected tropical disease statusInfectious corneal ulceration: a proposal for neglected tropical disease status
2019)‎. Infectious corneal ulceration: a proposal for neglected tropical disease status. Bulletin of the World Health ...
https://extranet.who.int/iris/restricted/handle/10665/330130?locale-attribute=zh&
Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study | British Journal...Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study | British Journal...
Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study ... Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study ... Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study ...
https://bjo.bmj.com/content/100/5/588.citation-tools
Corneal Nerve Fiber Loss Relates to Cognitive Impairment in Patients with Parkinsons Disease | Research SquareCorneal Nerve Fiber Loss Relates to Cognitive Impairment in Patients with Parkinson's Disease | Research Square
Background Cognitive impairment in Parkinsons disease (PD) adversely influences quality of life. There is currently no ... corneal nerve branch density; CNFL, corneal nerve fiber length; UPDRS, unified Parkinsons disease rating scale. ... Corneal nerve fiber density (CNFD), corneal nerve branch density (CNBD) and corneal nerve fiber length (CNFL) were quantified ... Parkinsons disease with mild cognitive impairment; PDD, Parkinsons disease dementia; UPDRS, unified Parkinsons disease ...
https://www.researchsquare.com/article/rs-112941/v1
ZFIN Human Disease: spondylometaphyseal dysplasia with corneal dystrophyZFIN Human Disease: spondylometaphyseal dysplasia with corneal dystrophy
autosomal recessive disease spondylometaphyseal dysplasia autosomal recessive disease spondylometaphyseal dysplasia Show first ... Human Disease (DOID:0112303) Relationships is a type of: ... Zebrafish Disease Models Society (ZDMS) * Genetics Society of ... A spondylometaphyseal dysplasia characterized by spondylometaphyseal dysplasia and corneal dystrophy that has_material_basis_in ...
https://www.zfin.org/action/ontology/term-detail/DOID:0112303
corneal Diseasecorneal Disease
How is corneal laceration different from corneal abrasion?. Though corneal abrasion and corneal laceration sound similar, on a ... There are several conditions like Keratoconus, corneal clouding, corneal infection, corneal dystrophy and corneal injury that ... Category: corneal Disease. Posted on April 15, 2020. May 11, 2020. 10 Things To Know About Corneal Transplant. The cornea is ... Recurrent Corneal Erosion, Corneal Perforation, Corneal Neovascularisation, Iridocorneal Endothelial Syndrome, and Corneal ...
https://www.dishaeye.org/blog/category/corneal-disease/
Orphan Drug Status for Corneal Cross-Linking in KeratoconusOrphan Drug Status for Corneal Cross-Linking in Keratoconus
Corneal cross-linking is the first medical therapy available in the US to slow disease progress. ... Artificial Intelligence and Corneal Diseases * Perioperative Care of the Patient With eye Pathologies Undergoing Nonocular ... Other options have included corneal implants and corneal transplantation.. The new treatment works by strengthening the cross- ... Corneal collagen cross-linking using UVA light with riboflavin photosensitizer is the first medical therapy available in the ...
http://www.medscape.com/viewarticle/749720
International Journal of Keratoconus and Ectatic Corneal DiseasesInternational Journal of Keratoconus and Ectatic Corneal Diseases
Corneal disorders in floppy eyelid syndrome. Cornea 1994;13:33-42.. * Histopathologic features of the floppy eyelid syndrome: ... Corneal melt and perforation secondary to floppy eyelid syndrome in the presence of rheumatoid arthritis [letter]. Br J ... Risk factors and prognosis for corneal ectasia after LASIK. Ophthalmology 2003;110:p.267. ...
https://www.ijkecd.com/abstractArticleContentBrowse?jCode=IJKECD&jid=21&abstractArticle=abstractArticle&documentType=Article&art_volume=3&art_issue=1&id=2002
punctate or nodular corneal dystrophy | Hereditary Ocular Diseasespunctate or nodular corneal dystrophy | Hereditary Ocular Diseases
Changes of Clinical Manifestation of Granular Corneal Deposits Because of Recurrent Corneal Erosion in Granular Corneal ... Changes of Clinical Manifestation of Granular Corneal Deposits Because of Recurrent Corneal Erosion in Granular Corneal ... Corneal Dystrophy, Granular. Clinical Characteristics. Ocular Features: The corneal opacities in this disorder are usually ... Three autosomal dominant corneal dystrophies map to chromosome 5q. Stone EM, Mathers WD, Rosenwasser GO, Holland EJ, Folberg R ...
https://disorders.eyes.arizona.edu/category/alternate-names/punctate-or-nodular-corneal-dystrophy
Corneal Disease and Surgery
Join our team! We are hiring. Click on job openings and apply today. ...
https://www.midwesteyecare.com/midwest-eye-surgery-center/corneal-disease-and-surgery/
Corneal Disease | Thompson OpticsCorneal Disease | Thompson Optics
... but they can be damaged by injury or disease, so care needs to be taken. ...
https://www.thompsonoptics.com/tag/scl_ttl/
Corneal Diseases - Perfect Sight Centre
Corneal Diseases. Brief overview of Cornea and Ocular Surface DiseasesI am Dr. Ashu Agarwal, Ophthamologist. My area of ... Ectatic corneal diseases like keratoconus, keratoglobus and pellucid marginal degeneration. - Pterygium. - Corneal dystrophies ... The clinic caters to the following Cornea & External eye diseases:. - Corneal infections. - Eye allergies Corneal complications ... cells that maintain corneal clarity). - Pachymetry- Measurement of corneal thickness. - Corneal Topography (by Orbscan)- ...
http://perfectsightcentre.com/corneal-diseases/
IMSEAR at SEARO: The pattern of corneal diseases in Punjab.
The pattern of corneal diseases in Punjab. Indian Journal of Ophthalmology. 1982 Jul; 30(4): 333-5. ...
https://imsear.searo.who.int/handle/123456789/70378
Impact of corneal disease from patients' and ophthalmologists' perspectives<...
Vreijsen, E., Elsman, E. B. M., van Nispen, R., Nuijts, R., & van Rens, G. (2019). Impact of corneal disease from patients and ... Impact of corneal disease from patients and ophthalmologists perspectives. Eline Vreijsen*, Ellen Bernadette Maria Elsman, ... Vreijsen E, Elsman EBM, van Nispen R, Nuijts R, van Rens G. Impact of corneal disease from patients and ophthalmologists ... Vreijsen, E, Elsman, EBM, van Nispen, R, Nuijts, R & van Rens, G 2019, Impact of corneal disease from patients and ...
https://research.vumc.nl/en/publications/impact-of-corneal-disease-from-patients-and-ophthalmologists-pers
Five questions: FSU researcher explains work to treat corneal disease - Florida State University NewsFive questions: FSU researcher explains work to treat corneal disease - Florida State University News
Five questions: FSU researcher explains work to treat corneal disease. By: Kathleen Haughney , Published: January 5, 2022. , 8: ... Fuchs dystrophy is a degenerative disease of the eye and specifically, the cornea. A layer of cells in the cornea (corneal ... Home / News / Health & Medicine / Five questions: FSU researcher explains work to treat corneal disease ... Corneal endothelial cells can respond to certain growth factor proteins. Such growth factors can stimulate corneal endothelial ...
https://news.fsu.edu/news/health-medicine/2022/01/05/five-questions-fsu-researcher-explains-work-to-treat-corneal-disease/
Neovascularization, Corneal, CL-related: Background, Pathophysiology, EpidemiologyNeovascularization, Corneal, CL-related: Background, Pathophysiology, Epidemiology
Ocular insult, including infectious keratitis, immunological conditions, corneal trauma, alkali injury, and contact lens wear ( ... Artificial Intelligence and Corneal Diseases * Perioperative Care of the Patient With eye Pathologies Undergoing Nonocular ... Clinical correlates of common corneal neovascular diseases: a literature review. Int J Ophthalmol. 2015. 8 (1):182-93. [QxMD ... Corneal vascularization due to corneal contact lenses: the clinical picture. Trans Am Ophthalmol Soc. 1967. 65:333-40. [QxMD ...
http://emedicine.medscape.com/article/1195886-overview
Corneal Disease | River Oaks Family OptometryCorneal Disease | River Oaks Family Optometry
Results of search for 'su:{Corneal diseases}' › WHO HQ Library catalog
Diseases of the cornea / Merrill Grayson. by Grayson, Merrill.. Edition: 2nd ed.Material type: Text; Format: print Publication ... Corneal disorders : clinical diagnosis and management / [editor], Howard M. Leibowitz and seventeen contributing authors. by ... Epidemiology and microbiology of corneal suppuration, September 1985-August 1987 / editors, Madan P. Upadhyay, Purna C. D. ...
https://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7BCorneal%20diseases%7D
Corneal tissue levels of topically applied ciprofloxacinCorneal tissue levels of topically applied ciprofloxacin
The purpose of this study is to compare corneal tissue ciprofloxacin levels in patients exposed to three ciprofloxacin dosing ... Corneal Diseases / metabolism * Corneal Diseases / surgery * Humans * Keratoplasty, Penetrating * Ophthalmic Solutions * Tissue ... corneal epithelium was left intact, whereas in group 3 corneas were abraded. Corneal tissue samples were surgically obtained. ... Corneal tissue levels of topically applied ciprofloxacin Cornea. 1995 Mar;14(2):152-6. ...
https://pubmed.ncbi.nlm.nih.gov/7743798/?dopt=Abstract
Cornea: Overview of Corneal Diseases and Common SymptomsCornea: Overview of Corneal Diseases and Common Symptoms
Corneal diseases come in different forms such as Keratoconus, Bullous keratopathy and so on. Get a glimpse into the symptoms of ... corneal diseases to have them detected if any at early stages. ... Common Symptoms of Corneal Diseases. You may need to seek ... Corneal diseases are serious complications, leading to distortion, swelling, scarring or even blindness. ... Types of Corneal Diseases and Related Symptoms. Sometimes, apart from minor injuries, corneal diseases occur for which you will ...
https://neoretina.com/blog/common-symptoms-of-corneal-diseases/
Corneal Disease | The Scleral Lens Center At Oakbrook OptometryCorneal Disease | The Scleral Lens Center At Oakbrook Optometry
... but they can be damaged by injury or disease, so care needs to be taken. ...
https://www.drsnyder.org/eye-care-services/scleral-lenses-optometrist/what-you-should-know-about-corneal-disease/
Best Ophthalmologists for Corneal Diseases in Doha, Qatar | HeliumDocBest Ophthalmologists for Corneal Diseases in Doha, Qatar | HeliumDoc
... for Corneal Diseases in Qatar. browse best doctors based on patient reviews ... Eye Infections, DohaEye Allergies, DohaCataract Surgery, DohaEye Examination, DohaCorneal Diseases, DohaEyelid Diseases, Doha ... Specializes in treating and preventing the diseases that affect the eyes and vision. ...
https://www.heliumdoc.com/doctors/ophthalmologist-corneal+diseases/
Cornea Transplant Surgeon In Bangalore | Corneal Disease In BangaloreCornea Transplant Surgeon In Bangalore | Corneal Disease In Bangalore
Cornea transplant surgeon at Sight Years Eye Clinic in Bangalore treats corneal disease by using corneal transplant surgery. ... The primary benefit of corneal transplantation is restoration of vision that is lost specifically due to corneal disease. ... A cornea can be damaged as a result of injury, infection, or corneal disease such as Fuchs Dystrophy or keratoconus. ... Patients undergoing a corneal transplant will be able to use any donated cornea. Unlike other types of transplants, corneal ...
https://www.sightyearseyeclinic.com/cornea-transplantation.html
Stem Cells Therapy for Corneal Blindness - Full Text View - ClinicalTrials.govStem Cells Therapy for Corneal Blindness - Full Text View - ClinicalTrials.gov
Condition or disease Intervention/treatment Phase Corneal Injuries Corneal Burns Corneal Scars and Opacities Biological: Ex- ... Corneal Injuries. Eye Injuries. Facial Injuries. Craniocerebral Trauma. Trauma, Nervous System. Nervous System Diseases. ... defined as involving the anterior 200 microns of the corneal stroma on ASOCT imaging) corneal wounds, ulcers, burns and scars. ... Stem Cells Therapy for Corneal Blindness (ExCell). The safety and scientific validity of this study is the responsibility of ...
https://clinicaltrials.gov/ct2/show/NCT02948023?term=NCT02948023&draw=2&rank=1
Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus - Full Text View...Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus - Full Text View...
History of corneal disease (e.g., herpes simplex, herpes zoster keratitis, corneal melt, corneal dystrophy, etc.); ... Corneal Diseases. Eye Diseases. Riboflavin. Pharmaceutical Solutions. Ophthalmic Solutions. Vitamin B Complex. Vitamins. ... Condition or disease Intervention/treatment Phase Progressive Keratoconus Drug: Paracel 1 Drug: Paracel Placebo Drug: Paracel 2 ... Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus. The safety and ...
https://www.clinicaltrials.gov/ct2/show/NCT03442751
Corneal Disease (Disorder of Cornea): Symptoms, Diagnosis and Treatment - SymptomaCorneal Disease (Disorder of Cornea): Symptoms, Diagnosis and Treatment - Symptoma
Corneal Disease (Disorder of Cornea): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis. ... Is it possible to prevent corneal disease? Many corneal diseases are preventable by reducing risk factors. [rxlist.com] ... What is the treatment for corneal disease? Treatment is tailored to the individual disease and the individual patient. ... Corneal disease can cause the cornea to become opaque or cloudy, preventing light from passing through clearly. [stlouis-eye. ...
https://www.symptoma.com/en/info/corneal-disease
Corneal Disease | Specialty Contact Lens Center at Sight Improvement CenterCorneal Disease | Specialty Contact Lens Center at Sight Improvement Center
laser | Breaking News Related to Macular Degeneration, Cataract, Glaucoma, Corneal Disease and Other Eye Conditions
Enter your email address in the box below to receive an email whenever new information is published on this blog.. ...
https://eyedocnews.com/00tag/laser/
GlaucomaBlindnessTransplantationDisordersEpithelialConfocal microscopyOphthalmologyOpacitiesConjunctivalEctasiaTransplantsInjuriesKeratoconus and cornealAbrasionPenetrating keratoplastyComplicationsEpisodes of recurrent corneal erosionsFuchsKeratitisLacerationAbrasionsNeed a corneal transplantSymptomsDystrophiesUlcerUlcersRetinalRegarding corneal transplantSurgeryDisorderInfectionsEpitheliumPattern of cornealEdemaMacular DegenerationInfectiousErosionsTreat cornealPerforationSevere cornealEndothelial cellsSuperficial cornealTreatmentsOcular DiseasesLimbalContact lensUlcerationClinicalGraft rejectionTissueThicknessSensitivitySystemic diseasesOccurDiagnosisDonorCorneasCornea becomes cloudyTraumaDiabetic Eye DiseaseRetina
Glaucoma8
  • The first year after a transplant is the most crucial, because most complications, if they occur, will occur within the first year of the transplant.The more common complications include increased eye pressure which can cause damage to the eye nerve (glaucoma) and corneal graft rejection. (perfectsightcentre.com)
  • Dr. Asaria specializes in the diagnosis and treatment of acute and chronic eye diseases including injuries and infections, as well as, the diagnosis and care of patients with Diabetes, Hypertension, Macular Degeneration, Ocular Surface Disease (Dry Eye), Glaucoma, corneal and retinal pathologies. (imatrix.com)
  • Secondary NVG, the major cause of which is iCRVO, is a very aggressive, rare form of glaucoma, responsible for 3.9 % of glaucoma cases, but contributing disproportionately to blindness from all eye diseases. (europa.eu)
  • Glaucoma in general is more than a single disease entity: it is a group of conditions characterized by progressive optic nerve degeneration (detectable by pathological cupping of the optic disc) and loss of visual function, ultimately resulting in total blindness. (europa.eu)
  • However, there are many forms of rare secondary glaucomas that develop following other eye diseases, including secondary neovascular glaucoma (NVG) most frequently presenting following ischemic central retinal vein occlusion (iCRVO). (europa.eu)
  • Diabetic eye diseases affect people with type 1 or type 2 diabetes and include diabetic retinopathy, macular edema, glaucoma, and cataracts. (2020eyeq.com)
  • People who have diabetes have double the chance of developing glaucoma, according to the National Institute of Diabetes and Digestive and Kidney Diseases. (2020eyeq.com)
  • Loss of side vision can occur with open-angle glaucoma, although you probably won't notice any change in your vision in the early stages of the disease. (2020eyeq.com)
Blindness9
  • What is corneal blindness/ visual impairment? (perfectsightcentre.com)
  • This kind of visual impairment is called corneal blindness. (perfectsightcentre.com)
  • and as a progressive disease, it will ultimately lead to blindness. (fsu.edu)
  • The current paper proposes a novel hypothesis for the treatment and prevention of corneal blindness in disorders such as keratoconus as an alternative to the gold standard treatment of penetrating or partial thickness keratoplasty. (symptoma.com)
  • The loss or dysfunction of human corneal endothelial cells (hCEnCs) is a leading cause of blindness due to corneal failure. (mdpi.com)
  • Blindness is often caused by corneal diseases. (europa.eu)
  • The role of the national register in addressing blinding cataract, corneal blindness, eradication of congenital rubella syndrome and care of blind people in Oman was also examined. (who.int)
  • If untreated, this condition leads to the formation of irreversible corneal opacities and blindness. (who.int)
  • It is responsible, at present, for more than 3% of the world's blindness but the number keeps changing due to the effect of socioeconomic development and current control programmes for this disease. (who.int)
Transplantation11
  • Treatments of corneal disorders include medicines, corneal transplantation, and corneal laser surgery. (medlineplus.gov)
  • Other options have included corneal implants and corneal transplantation. (medscape.com)
  • This is the only type of visual impairment that can be treated by corneal transplantation. (perfectsightcentre.com)
  • In the event of graft failure due to rejection, corneal transplantation may be repeated several times if previous transplants have failed. (perfectsightcentre.com)
  • The primary benefit of corneal transplantation is restoration of vision that is lost specifically due to corneal disease. (sightyearseyeclinic.com)
  • Further to detailed evaluation of individual cases, your corneal surgeon will discuss the risks of corneal transplantation with you further. (sightyearseyeclinic.com)
  • Corneal transplantation with a healthy donor cornea has been the only available treatment for corneal endothelial disease. (mdpi.com)
  • Dr Leonard Ang specialises in a wide range of corneal disorders as well as in corneal transplantation. (langeye.sg)
  • In 2013, he completed a course on femtosecond laser correction, corneal ring implantation, and corneal femtosecond transplantation in Spain. (eximer.ua)
  • Diseases surgical technique developed since the start of the involving the corneal endothelium can be controlled twentieth century for the realization of corneal with endothelial or penetrating keratoplasties, and transplantation (CT). (bvsalud.org)
  • CT is the most common type those diseases that involve both the endothelium and of tissue transplantation made around the world, the corneal stroma generally require PK when there is substitution of all corneal layers (the (REINHART, 2011). (bvsalud.org)
Disorders9
  • Orphan-drug designation is designed to encourage companies to develop therapies for rare diseases and disorders that affect fewer than 200,000 Americans. (medscape.com)
  • Corneal disorders in floppy eyelid syndrome. (ijkecd.com)
  • Corneal disorders : clinical diagnosis and management / [editor], Howard M. Leibowitz and seventeen contributing authors. (who.int)
  • To assist State and local health agencies, health related organizations, and other public and private organizations in their efforts to prevent and control chronic diseases and disorders through research, development, capacity building, and. (federalgrantswire.com)
  • Their specialized medical skills are especially vital when the eyes are affected by disorders, injury, disease complications or degeneration. (weillcornell.org)
  • In addition to facial animation, children with facial motion disorders can have difficulty with feeding, swallowing, chewing, speaking, and closing their eyes, which can lead to acquired eye disease. (chop.edu)
  • The objective of this study was to determine the pattern of corneal disorders at Ekiti State University Teaching Hospital, Ado-Ekiti. (bvsalud.org)
  • Results: Corneal disorders accounted for 3.3% of the eye disorders seen during the period of study. (bvsalud.org)
  • Doctors of optometry (ODs) are eye health care professionals state-licensed to diagnose and treat diseases and disorders of the eye and visual system. (eyedoctor.io)
Epithelial3
  • This is another autosomal dominant corneal dystrophy resulting from mutations in the TGFBI gene (5q31) (others being Reis-Bucklers , Thiel-Behnke , lattice types I and IIIA, epithelial basement membrane disease , and Avellino ). (arizona.edu)
  • 0.5 million stromal and epithelial cells will be incorporated in 0.05ml of commercially available fibrin glue and pasted over the corneal lesion after epithelial debridement. (clinicaltrials.gov)
  • On exam, he had a circumlimbal corneal infiltrate with overlying epithelial breakdown and associated conjunctival injection. (uiowa.edu)
Confocal microscopy7
  • Corneal confocal microscopy (CCM) has been used as a non-invasive tool for quantifying small nerve fibre damage in PD. (researchsquare.com)
  • Corneal confocal microscopy differentiates patients with Parkinson's disease with and without autonomic involvement. (bvsalud.org)
  • Corneal confocal microscopy (CCM) is a rapid ophthalmic technique that can quantify small nerve damage in a range of peripheral and autonomic neuropathies. (bvsalud.org)
  • In vivo corneal confocal microscopy of human corneal nerves in health and systemic diseases: a. (college-optometrists.org)
  • Misra 2017] - "Automated analysis of in vivo confocal microscopy images of corneal nerves", Stuti L Misra, Jonathan D Oakley, Charles N McGhee, 1 Ellen F Wang, Dipika V Patel, Patrick M Tarwater, Joseph L Mankowski. (voxeleron.com)
  • Oakley 2020] - "Deep Learning-Based Analysis of Macaque Corneal Sub-Basal Nerve Fibers in Confocal Microscopy Images", Jonathan D. Oakley, Daniel B. Russakoff, Megan E. McCarron, Rachel L. Weinberg, Jessica M. Izzi, Stuti L. Misra, Charles N. McGhee, Joseph L. Mankowski. (voxeleron.com)
  • McCarron 2020] - "Combining In Vivo Corneal Confocal Microscopy with Deep Learning-based Analysis Reveals Sensory Nerve Fiber Loss in Acute SIV Infection", ME McCarron, RL Weinberg, JM Izzi, SE Queen, SL Misra, DB Russakoff, J Oakley, J Mankowski. (voxeleron.com)
Ophthalmology4
  • A 45 year-old male was referred to the UIHC ophthalmology department with concern for possible corneal ulcer of the left eye. (uiowa.edu)
  • After completing an ophthalmology residency and serving as chief resident at the University of Wisconsin-Madison, he received further training through a cornea and external disease fellowship at the University of California-Davis. (rochester.edu)
  • PetsEyes BioCorneaVet is a trustable decellularized/bioengineered porcine-sourced cornea in the treament of various corneal diseases in veterinary ophthalmology. (petseyes.cn)
  • After completing his internship in ophthalmology at the Department of Eye Diseases of the Kyiv Medical Institute, he worked as an ophthalmologist at the Kyiv Regional Clinical Hospital and Deputy Chief Medical Officer of Zgurovsk Central Regional Hospital in Kyiv region. (eximer.ua)
Opacities3
  • The corneal opacities in this disorder are usually located in the anterior stroma of the central cornea, and consist of discrete grayish-white, irregular granules with sharp margins. (arizona.edu)
  • Later in life, patients are reported to develop subepithelial opacities and a corneal haze. (cdc.gov)
  • The disease eventually progresses over time leading to corneal opacities and loss of vision. (cdc.gov)
Conjunctival2
  • The authors reported no significant difference in the mean change between the treatment and placebo groups for OSDI score, conjunctival and corneal staining, TBUT and Schirmer's test. (reviewofoptometry.com)
  • A corneal biopsy specimen from the more severely affected patient and biopsy specimens from a patient whose case had been previously reported demonstrated crystals resembling cholesterol or cholesterol ester and complex lipid inclusions in corneal and conjunctival fibroblasts. (elsevier.com)
Ectasia2
  • The company is currently seeking FDA orphan drug status in the treatment of corneal ectasia following refractive surgery. (medscape.com)
  • Risk factors and prognosis for corneal ectasia after LASIK. (ijkecd.com)
Transplants6
  • There are three types of corneal transplants that are done depending on cases. (dishaeye.org)
  • Keratoconus is a degenerative disease of the eye that is characterized by progressive thinning of the cornea and represents the leading cause of corneal transplants in the United States. (medscape.com)
  • Corneal transplants are one of the most common and most successful of all transplants. (perfectsightcentre.com)
  • Unlike other types of transplants, corneal transplants do not require the donor and recipient to have the same blood type. (sightyearseyeclinic.com)
  • Less commonly, corneal transplants can be done on an urgent basis to treat severe Corneal Infections, or to repair or 'patch up' severe thinning, defects or perforations in the cornea or sclera (the sclera is the white coating of the eye). (singhealth.com.sg)
  • Corneal transplants are commonly used for treating two types of corneal problems. (ofc-boioph.com)
Injuries2
  • Sometimes, apart from minor injuries, corneal diseases occur for which you will need to seek help from an ophthalmologist or eye care professional. (neoretina.com)
  • A cloudy or opaque cornea can occur from scarring of any cause (e.g., injuries or infections) or cloudy swelling of the cornea due to damage or ageing of the innermost layer of cells of the cornea (known as the corneal endothelial layer). (singhealth.com.sg)
Keratoconus and corneal2
  • Dr. Swapnali is a skilled surgeon and her special interests include LASIK and refractive surgeries, management of keratoconus and corneal transplant surgeries. (neoretina.com)
  • Patients with keratoconus and corneal scarring have an excellent prognosis . (symptoma.com)
Abrasion4
  • Acanthamoeba likely invade the cornea through a physical opening, such as a minor abrasion, in the corneal epithelium. (cdc.gov)
  • Sixty patients (60%) had noninfectious corneal diseases, most commonly dry eye syndrome (26.7%, n=16), followed by corneal abrasion (18.3%, n=11). (mssm.edu)
  • A corneal abrasion occurs when the cornea has a scratch on its surface. (medium.com)
  • If you have a corneal abrasion, you may feel like there is something stuck in your eye or you may feel a gritty sensation. (medium.com)
Penetrating keratoplasty3
  • If the inner and outer layers of the cornea are damaged, then you might be recommended to undergo a full-thickness corneal transplant, also known as penetrating keratoplasty. (dishaeye.org)
  • The purpose of this study is to compare corneal tissue ciprofloxacin levels in patients exposed to three ciprofloxacin dosing regimens before undergoing penetrating keratoplasty. (nih.gov)
  • With the development of new surgical techniques, instrumentation and pharmacological advances, corneal transplant procedures can undergo changes directly in the clinical profile of patients with the indication for penetrating keratoplasty technique. (bvsalud.org)
Complications2
  • However, vision loss and chronic eye pain are potential complications of corneal disease so it is important to review treatment options carefully with an eye doctor. (symptoma.com)
  • Dry eye disease comes with symptoms like burning eyes, blurred vision, pain, redness, and potential complications like eye infections and corneal ulcers. (baysideeyecare.com)
Episodes of recurrent corneal erosions2
  • The number and morphology of the granular deposits change throughout life, influenced to some extent by episodes of recurrent corneal erosions and age of patients. (arizona.edu)
  • Painful episodes of recurrent corneal erosions occur in the first decade of life but decrease during adolescence. (cdc.gov)
Fuchs3
  • Fuchs' dystrophy is a degenerative disease of the eye and specifically, the cornea. (fsu.edu)
  • A cornea can be damaged as a result of injury, infection, or corneal disease such as Fuchs' Dystrophy or keratoconus. (sightyearseyeclinic.com)
  • 3. Symptomatic corneal edema associated with endothelial dysfunction which may be secondary to Fuchs' corneal dystrophy or pseudophakic bullous keratopathy. (who.int)
Keratitis1
  • Eyelid retraction can lead to lagophthalmos and exposure keratitis, which can cause mild ocular surface irritation to vision-threatening corneal decompensation. (eyewiki.org)
Laceration3
  • What Is Corneal Laceration? (dishaeye.org)
  • A corneal laceration is one such issue that should not be taken lightly. (dishaeye.org)
  • Corneal laceration occurs when something hits the eye with a significant force like a ball or metallic rod, causing a cut on the cornea. (dishaeye.org)
Abrasions2
  • Corneal abrasions can be caused by makeup brushes, fingernails, or even tree branches. (medium.com)
  • Fluorescein dye drops into the eye to detect corneal abrasions because fluorescein colour will stick there and reflect when we use a blue ray of light on the eye. (diagnosisbook.com)
Need a corneal transplant1
  • People whose cornea is damaged or unhealthy cornea might need a corneal transplant. (dishaeye.org)
Symptoms14
  • The symptoms of a corneal disorder or disease due to allergies include itching, redness, burning sensation, tearing, stinging and watery discharge. (neoretina.com)
  • During the routine eye checkups and by knowing common symptoms of the corneal disease, such conditions are caught early. (neoretina.com)
  • Diseases of the cornea can cause loss of vision, pain, and associated symptoms such as glare and headaches . (symptoma.com)
  • Systemic symptoms : these are not unusual in patients with acute corneal disease, particularly headaches , mild nausea and feeling generally run down. (symptoma.com)
  • Based on the scale for outcomes in Parkinson's disease for autonomic symptoms (SCOPA-AUT), patients with PD were classified into those without autonomic symptoms (AutD-N), with single (AutD-S), and multiple (AutD-M) domain autonomic dysfunction. (bvsalud.org)
  • Corneal nerve fiber pathology was quantified using CCM, and the relationship with autonomic symptoms was explored. (bvsalud.org)
  • Corneal nerve fiber density (CNFD), corneal nerve branch density (CNBD), corneal nerve fiber length (CNFL), and CNBD/CNFD ratio were lower in PD patients with autonomic symptoms compared to those without autonomic symptoms. (bvsalud.org)
  • Autonomic symptoms correlated positively with CNFD (r = -0.350, p = 0.004), and were not related to Levodopa equivalent daily dose (r = 0.042, p = 0.733) after adjusting for age, disease severity , disease duration or cognitive function . (bvsalud.org)
  • PD patients with autonomic symptoms have corneal nerve loss, and CCM could serve as an objective ophthalmic imaging technique to identify patients with PD and autonomic symptoms. (bvsalud.org)
  • It is important to know if your eye symptoms are caused by an autoimmune disease or some other factor. (walnutcreekeyedoctor.com)
  • Bilberry extract can improve tear secretion and plasmatic antioxidant potential in subjects suffering from dry eye disease symptoms. (greenmedinfo.com)
  • Have your eyes checked regularly to ensure that early symptoms of eye diseases are spotted and treated timely. (langeye.sg)
  • The most common symptoms of thyroid disease are red eyes, watery eyes, double vision, bulging eyes, and difficulty closing your eyes. (medium.com)
  • Unfortunately, many types of diabetic eye diseases only cause symptoms after your vision has already been damaged. (2020eyeq.com)
Dystrophies1
  • There are several types of corneal degenerations and dystrophies. (neoretina.com)
Ulcer1
  • Corneal ulcer A corneal ulcer is a corrosion that is characteristically indicated by a red, painful eye. (symptoma.com)
Ulcers1
  • In this prospective interventional study patients with superficial corneal pathologies like scars, ulcers and burns will undergo a surgical procedure. (clinicaltrials.gov)
Retinal5
  • We report the clinical and electrophysiologic findings in three patients with Bietti's crystalline corneal-retinal dystrophy. (elsevier.com)
  • The initial evaluation in one patient demonstrated diffuse disease involving retinal pigment epithelium and choriocapillaris with severe widespread disturbance of retinal function. (elsevier.com)
  • Two brothers had regional involvement of the posterior pole with disturbances of retinal function attributable to localized disease, and there was only mild progression in these patients. (elsevier.com)
  • A new study reported in the journal Cell Reports has shed light on this by showing that, by growing human pluripotent stem cells on different forms of a protein called laminin, they can be induced to become corneal cells, retinal cells, and others. (alliancecelltechnologies.eu)
  • Summary: Researchers revealed that culturing human induced pluripotent stem cells with different isoforms of the extracellular component laminin led to the creation of cells specific to different parts of the eye, including retinal, corneal, and neural crest cells. (alliancecelltechnologies.eu)
Regarding corneal transplant1
  • Want to consult some of the best eye specialists in West Bengal regarding corneal transplant? (dishaeye.org)
Surgery11
  • A corneal transplant is a fairly safe procedure but like any other surgery, it involves a couple of risks. (dishaeye.org)
  • I deal primarily with diseases of the cornea and ocular surface, cataract surgery and refractive surgery (including LASIK). (perfectsightcentre.com)
  • What are the benefits of corneal transplant surgery? (sightyearseyeclinic.com)
  • Anti-rejection medication is given to the patient after the transplant surgery to help their body accept the corneal tissue. (sightyearseyeclinic.com)
  • Prognosis The risk of corneal grafting depends primarily on why the surgery is required. (symptoma.com)
  • Conservative treatment with topical steroids and lubricants, bandage contact lens, and lacrimal punctal occlusion surgery resulted in the successful resolution of the corneal perforation with satisfactory visual recovery in the right eye. (lidsen.com)
  • During the surgery, the central corneal area, known as a corneal button, is removed and replaced with tissue from another person's eye. (ofc-boioph.com)
  • Corneal decompensation after intraocular ophthalmic surgery -- Missouri, 1998. (cdc.gov)
  • During JANUARY 8-14, 1998, six of eight patients undergoing elective intraocular surgery at a Veterans Affairs medical center (VAMC) in St. Louis, Missouri, developed corneal endothelial decompensation (corneal edema and opacification) 24 hours after surgery. (cdc.gov)
  • A case was defined as corneal endothelial decompensation within 24 hours after surgery in any patient undergoing intraocular ophthalmic surgery during January 5-14, 1998. (cdc.gov)
  • To ascertain cases and to determine the background rate of corneal decompensation, medical records of patients undergoing ophthalmic surgery during September 1997-January 1998 were reviewed. (cdc.gov)
Disorder1
  • The etiology of corneal disorder varies from one geographical location to another. (bvsalud.org)
Infections2
  • Antibacterial eye drops are prescribed to treat minor corneal infections. (neoretina.com)
  • The disease will begin to destroy your body's own immune system, weakening it so that you are liable to develop infections - including vision problems. (walnutcreekeyedoctor.com)
Epithelium4
  • In groups 1 and 2, corneal epithelium was left intact, whereas in group 3 corneas were abraded. (nih.gov)
  • In the second procedure, the central corneal epithelium will be removed using a surgical sponge. (clinicaltrials.gov)
  • To evaluate the safety and efficacy of epithelium-on corneal collagen cross-linking (CXL) in impeding the progression of, and/or reducing corneal curvature (Kmax) in eyes with progressive keratoconus. (clinicaltrials.gov)
  • Upon binding to mannose glycoproteins of the corneal epithelium, Acanthamoeba secretes proteins cytolytic to the epithelium as well as proteases that facilitate further penetration 11-15 . (cdc.gov)
Pattern of corneal1
  • IMSEAR at SEARO: The pattern of corneal diseases in Punjab. (who.int)
Edema2
  • Corneal edema is present nasally with Descemet's membrane folds. (uiowa.edu)
  • 2014). Corneal Edema. (cdc.gov)
Macular Degeneration1
  • Diagnosed or Treated Age-related macular degeneration (AMD) includes diagnosis codes specifying degenerative diseases of the macula, including macula drusen, dry-form AMD (including geographic atrophy), and wet-form AMD (including active choroidal neovascularization). (cdc.gov)
Infectious4
  • We demonstrate that high background antimicrobial drug use may be responsible for much of the observed decline in trachoma and discuss its potential role in eliminating this infectious disease. (cdc.gov)
  • Other infectious diseases such as syphilis, chancroid, tuberculosis, and leprosy also began to subside in Europe and the United States during this time. (cdc.gov)
  • Addressing the importance of antimicrobial agents in the disappearance of these infectious diseases retrospectively is difficult. (cdc.gov)
  • Trachoma is one of the oldest infectious diseases known to mankind. (who.int)
Erosions1
  • A very rare form of superficial corneal dystrophy with characteristics of frequent recurrent corneal erosions in the first decade of life and progressive loss of vision. (cdc.gov)
Treat corneal1
  • In 2011, he mastered a practical course on applying the UV-X-TM device (Switzerland) to treat corneal diseases (keratoconus and others). (eximer.ua)
Perforation5
  • Corneal melt and perforation secondary to floppy eyelid syndrome in the presence of rheumatoid arthritis [letter]. (ijkecd.com)
  • Adamo GG, D'Angelo S, Yu AC, Pellegrini M, Bernabei F, Scorcia V, Giannaccare G. Bilateral Corneal Perforation in a Patient with Chronic Ocular Graft-Versus-Host Disease: A Case Report and Literature Review. (lidsen.com)
  • Corneal perforation is an uncommon but vision-threatening manifestation of GVHD. (lidsen.com)
  • We reported the case of a 65-year-old male patient who developed corneal perforation sequentially in both eyes 3 years after receiving HSCT. (lidsen.com)
  • Therefore, corneal perforation can occur as the presenting manifestation of ocular GVHD. (lidsen.com)
Severe corneal2
  • Professor Nick Di Girolamo is a research-focused academic leading an internationally recognised group whose mission is to restore sight in patients blinded from severe corneal disease. (edu.au)
  • Direct contact with escaping compressed gas or liquid sulfur dioxide can produce severe corneal damage and frostbite injury to the skin. (cdc.gov)
Endothelial cells4
  • A layer of cells in the cornea (corneal endothelial cells) controls the flow of water into the cornea. (fsu.edu)
  • If the layer of corneal endothelial cells is not healthy (i.e., if the population of such cells decreases), then you can get corneal swelling due to an uncontrolled flow of water. (fsu.edu)
  • Corneal endothelial cells can respond to certain growth factor proteins. (fsu.edu)
  • Such growth factors can stimulate corneal endothelial cells to divide and grow, thereby effectively healing the cornea. (fsu.edu)
Superficial corneal1
  • This is a investigative initiated, comparative pilot clinical trial to ascertain the safety of application of ex-vivo cultivated limbal stem cells in human eyes for treating different superficial corneal pathologies. (clinicaltrials.gov)
Treatments5
  • A Florida State University technology developed to treat an incurable eye condition has proven so effective in clinical trials that investors have funded a third portion of Series A financing for Trefoil Therapeutics to support the further creation of treatments for corneal disease. (fsu.edu)
  • Refine Results Find a Corneal Disease Treatments Doctor Matching Results Treatments Medical Management Our doctors may prescribe antibiotics, antivirals, or antifungal medications if you have an infection caused by bacteria, virus, or fungus. (symptoma.com)
  • At any given time, UCSF is conducting more than 1,500 clinical trials to better understand disease and evaluate new treatments. (ucsfhealth.org)
  • Now that we can use different laminins to program stem cells to become particular cells found in different parts of the eye, we can harvest and apply them in treatments for a range of ocular diseases," last author Kohji Nishida says. (alliancecelltechnologies.eu)
  • Lifestyle Changes Allergies also about allergy Graves disease this article are included treatments for gives your dog the a brand Xalatan For Order pollen release about dry. (aimaindia.in)
Ocular Diseases3
  • To evaluate the red reflex of newborns, percentage of ocular diseases resulting in red reflex abnormality, and their relation with consanguinity in Southeast Turkey. (who.int)
  • Any transmission block at any part of the optical pathway of consanguinity and ocular diseases will be helpful in results in reflex abnormality that includes its absence, informing the public about risks of intermarriages. (who.int)
  • Cells cultured in this way could be used to treat various ocular diseases. (alliancecelltechnologies.eu)
Limbal1
  • Thousands of people have lost their eyesight due to damages to the cornea, such as trauma, absent limbal stem cells or diseases. (europa.eu)
Contact lens2
  • The incidence of the disease in the United States has been conservatively estimated at approximately one to two cases per million contact lens users, although these estimates need to be refined 9 , 10 . (cdc.gov)
  • Corneal and Contact Management includes professional activities performed by an optometrist related to the fitting of contact lenses to an eye, ongoing evaluation of the cornea's ability to sustain successful contact lens wear, and treatment of any external eye or corneal condition which can affect contact lens wear. (eyedoctor.io)
Ulceration1
  • Slit lamp photographs of the left eye (A, B) showing a peripheral curvilinear infiltrate with ulceration superonasally separated from the limbus by a clear corneal zone. (uiowa.edu)
Clinical11
  • Corneal vascularization due to corneal contact lenses: the clinical picture. (medscape.com)
  • Pre-clinical work in murine models have already demonstrated efficacy of this technique in curing murine corneal pathologies. (clinicaltrials.gov)
  • oral such download corneal sensitivity measurement and clinical importance and Ishikawa inner dancing linkage events slid been by spacecraft, hatred and RT-PCR. (oldandelegant.com)
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  • In vivo corneal microscopy has seen a recent resurgence in interest among both the research and clinical communities. (voxeleron.com)
Graft rejection1
  • Incidence of subsequent corneal graft rejection is estimated by one study to be 1.7 times higher in a setting of vascularized rather than nonvascularized host corneas. (medscape.com)
Tissue4
  • Corneal tissue samples were surgically obtained. (nih.gov)
  • Ciloxan corneal tissue concentrations (mean +/- SD) were 8.82 +/- 8.24 micrograms/g tissue in group 1, 166.20 +/- 336.94 micrograms/g tissue in group 2, and 938.30 +/- 1,081.51 micrograms/g tissue in group 3. (nih.gov)
  • The replacement corneal tissue is then sutured in place. (ofc-boioph.com)
  • High-resolution 3-T MR imaging helps characterize orbital and ocular soft-tissue lesions, permitting superior delineation of orbital soft tissues, cranial nerves, blood vessels, and blood flow and detection of intracranial extension of orbital disease. (radiologykey.com)
Thickness1
  • If your cornea is not completely damaged, and only partly affected (the front and middle layers), a partial-thickness corneal transplant is recommended. (dishaeye.org)
Sensitivity8
  • A sensitivity to light (photophobia) and excessive tear formation (lacrimation) can occur in this form of corneal dystrophy. (symptoma.com)
  • The ordinary components on download corneal sensitivity half suggested BBC 1, BBC 2, ITV, Channel 4 and Channel 5. (oldandelegant.com)
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Systemic diseases2
  • All were male, ranged in age from 43 to 85 years (median: 67 years), and had chronic systemic diseases such as coronary artery disease and hypertension. (cdc.gov)
  • He/she is medically trained to deliver total eye care: primary, secondary and tertiary (i.e., vision services, contact lenses, eye examinations, medical eye care and surgical eye care), diagnose general diseases of the body and treat ocular manifestations of systemic diseases. (eyedoctor.io)
Occur2
  • Occasionally autoimmune disease-related vision problems occur quickly and can become alarming. (walnutcreekeyedoctor.com)
  • Graft-versus-host disease (GVHD) is a serious complication that may occur in patients receiving allogeneic hematopoietic stem cell transplant (HSCT). (lidsen.com)
Diagnosis2
  • Knowledge of these findings can improve the early diagnosis of keratoconus, especially crucial in the era of corneal crosslinking therapy, which can often prevent progression of keratoconus before loss of BCVA. (aao.org)
  • Diagnosis codes are based on the International Classification of Diseases (ICD) system. (cdc.gov)
Donor5
  • If your cornea is damaged or unhealthy, your eye specialist may recommend a corneal transplant which involves replacing the damaged cornea with a healthy cornea from a deceased donor. (dishaeye.org)
  • A corneal transplant involves replacing a diseased or scarred cornea with a clear, healthy donor cornea. (perfectsightcentre.com)
  • However, the success depends on a number of factors- recepient's eye condition and corneal disease, donor cornea quality and the surgical technique and skill. (perfectsightcentre.com)
  • A corneal transplant is a surgical procedure that involves replacing the cloudy/scarred cornea with a donor cornea to restore vision. (singhealth.com.sg)
  • The established treatment is a corneal transplant, but in many cases this is not possible and donor corneas are often hard to come by. (europa.eu)
Corneas2
  • However, individuals who improperly store, handle or disinfect their lenses (e.g. , use tap water or homemade solutions for cleaning), swim/use hot tubs/shower while wearing lenses, come in contact with contaminated water, have minor damage to their corneas, or have previous corneal trauma are at increased risk of infection. (cdc.gov)
  • All patients had post-operative findings of persistent low visual acuity, cloudy corneas with corneal endothelial decompensation, and iris paralysis with dilated pupils. (cdc.gov)
Cornea becomes cloudy1
Trauma1
  • Corneal foreign body, trauma, and vernal keratoconjunctivitis were the leading known predisposing factors. (bvsalud.org)
Diabetic Eye Disease5
  • Are You at Risk for Diabetic Eye Disease? (2020eyeq.com)
  • Diabetic Eye Disease Awareness Month in November is the perfect time to schedule your appointment. (2020eyeq.com)
  • Who Gets Diabetic Eye Disease? (2020eyeq.com)
  • You're most likely to develop a diabetic eye disease if your blood sugar is often high. (2020eyeq.com)
  • Want to reduce your risk of diabetic eye disease? (2020eyeq.com)
Retina1
  • Most individuals with poor vision due to a diseased or cloudy cornea, whose nerve and retina at the back of the eye is still healthy, may benefit from a corneal transplant to see well. (singhealth.com.sg)