Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals.
Any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol (see GLYCERIDES), a sphingoid, a ceramide (CERAMIDES) (N-acylsphingoid) or a prenyl phosphate. (From IUPAC's webpage)
Trehalose is a non-reducing disaccharide composed of two glucose molecules linked by an alpha, alpha-1,1-glycosidic bond, naturally found in some plants and microorganisms, serving as a cryoprotectant and providing cellular protection against various stress conditions.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
The bovine variety of the tubercle bacillus. It is called also Mycobacterium tuberculosis var. bovis.
A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
Granulomatous disorders affecting one or more sites in the respiratory tract.
A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.
Inorganic and organic derivatives of sulfuric acid (H2SO4). The salts and esters of sulfuric acid are known as SULFATES and SULFURIC ACID ESTERS respectively.
Oligosaccharides containing two monosaccharide units linked by a glycosidic bond.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds.
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.
An increase in MITOCHONDRIAL VOLUME due to an influx of fluid; it occurs in hypotonic solutions due to osmotic pressure and in isotonic solutions as a result of altered permeability of the membranes of respiring mitochondria.
A genus of gram-positive, aerobic bacteria. Most species are free-living in soil and water, but the major habitat for some is the diseased tissue of warm-blooded hosts.
Mycolic acids are complex, long-chain fatty acids that are a major component of the cell wall of Mycobacterium species, including the causative agents of tuberculosis and leprosy, providing them with unique characteristics such as resistance to acid-alkali stability, pigmentation, and protection against host immune responses.
So-called atypical species of the genus MYCOBACTERIUM that do not cause tuberculosis. They are also called tuberculoid bacilli, i.e.: M. buruli, M. chelonae, M. duvalii, M. flavescens, M. fortuitum, M. gilvum, M. gordonae, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. kansasii, M. marinum, M. obuense, M. scrofulaceum, M. szulgai, M. terrae, M. ulcerans, M. xenopi.
Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)
Mitochondria in hepatocytes. As in all mitochondria, there are an outer membrane and an inner membrane, together creating two separate mitochondrial compartments: the internal matrix space and a much narrower intermembrane space. In the liver mitochondrion, an estimated 67% of the total mitochondrial proteins is located in the matrix. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p343-4)
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
Activities or games, usually involving physical effort or skill. Reasons for engagement in sports include pleasure, competition, and/or financial reward.
The field of medicine concerned with physical fitness and the diagnosis and treatment of injuries sustained in exercise and sports activities.
Illegitimate use of substances for a desired effect in competitive sports. It includes humans and animals.
Injuries incurred during participation in competitive or non-competitive sports.
Facilities having programs intended to promote and maintain a state of physical well-being for optimal performance and health.
Equipment required for engaging in a sport (such as balls, bats, rackets, skis, skates, ropes, weights) and devices for the protection of athletes during their performance (such as masks, gloves, mouth pieces).

Cord formation in MB/BacT medium is a reliable criterion for presumptive identification of Mycobacterium tuberculosis complex in laboratories with high prevalence of M. tuberculosis. (1/135)

We evaluated cord formation in MB/BacT broth as a rapid method for presumptive identification of the Mycobacterium tuberculosis complex. Kinyoun acid-fast-stained smears from 370 positive MB/BacT bottles were examined for the presence of serpentine cording. The smears were examined independently by two observers. Observer 1 (the supervisor of the mycobacteriology laboratory) examined all of the smears while observer 2 (a clinical microbiologist not familiar with acid-fast bacillus [AFB] microscopy) examined 148 randomly chosen smears that were read by observer 1 without knowledge of which smear was which. The sensitivity, specificity, and positive and negative predictive values of cording for the presumptive identification of M. tuberculosis read by observer 1 were 88.2, 97.4, 99.2, and 69.7%, respectively. These values were reported at 90.6, 52.3, 82.8, and 69. 7%, respectively, by observer 2. Our laboratory prevalence of M. tuberculosis among positive cultures was 78% during the time this study was conducted. At the time of positive signal of the MB/BacT bottles, the broth of the bottles had sufficient cell mass to allow for observation of the presence or absence of serpentine cording. The presence of cords in MB/BacT broth is a reliable criterion for rapid, predictive identification of the M. tuberculosis complex for laboratories with a high proportion of the M. tuberculosis complex when the smears are examined by a microbiologist who has experience with AFB staining.  (+info)

Trehalose 6,6'-dimycolate (Cord factor) enhances neovascularization through vascular endothelial growth factor production by neutrophils and macrophages. (2/135)

Trehalose 6,6'-dimycolate (TDM) plays important roles in the development of granulomatous inflammation during infection with Mycobacterium spp., Rhodococcus spp., etc. To reveal the augmenting effect of TDM on vascular endothelial growth factor (VEGF) production and neovascularization, we investigated murine granulomatous tissue air pouches induced by Rhodococcus sp. strain 4306 TDM dissolved in Freund's incomplete adjuvant (FIA), comparing them to pouches treated with FIA alone. Histologically, granulomatous tissue and new vessel formation, which reached a maximum at day 7, was greatly enhanced by treatment with TDM. At day 1, VEGF-positive neutrophils accumulated in the pouch wall with frequency of 95% of total infiltrating cells, adhering to TDM-containing micelles. By day 3, granulomatous tissue and new vessels started to develop, and VEGF-positive macrophages appeared in a small number and gradually increased in number thereafter. The pouch contents of VEGF, interleukin-1beta, tumor necrosis factor alpha, and transforming growth factor beta were significantly elevated in TDM-treated pouches, with peaks at days 1, 0.5, 1, and 3, respectively, compared to those of control pouches, while that of basic fibroblast growth factor showed no significant increase. Treatment with anti-VEGF antibody inhibited TDM-induced granulomatous tissue formation and neovascularization, and administration of recombinant VEGF into pouches treated with FIA alone induced neovascularization comparable to that in the TDM-treated pouches. Incubation of neutrophils and macrophages on TDM-coated plastic dishes increased the VEGF release. The present results indicate that TDM augments VEGF production by neutrophils and macrophages and induces neovascularization in the granulomatous tissue.  (+info)

Assessment of morphology for rapid presumptive identification of Mycobacterium tuberculosis and Mycobacterium kansasii. (3/135)

Mycobacterium tuberculosis often exhibits serpentine cording when grown in liquid medium, whereas Mycobacterium kansasii can be larger and cross-barred. We assessed the use of these morphologic characteristics as a cost-effective method for rapid presumptive identification of isolates from BACTEC bottles. Without specific training, using the Kinyoun acid-fast stain, definitive cording was found in 237 of 373 specimens positive for M. tuberculosis (64%) and cross-barring was recognized within 63 of 76 (83%) of the specimens positive for M. kansasii, giving sensitivities specificities, positive predictive values, and negative predictive values of 63.5, 96, 92, and 79%, respectively, for M. tuberculosis and 83, 95, 59, and 98%, respectively, for M. kansasii. With training and experience, these results improved to 74.5, 98, 96, and 84% and 93, 98, 79, and 98%, respectively. The major improvements were in distinguishing the pseudocording, or loose aggregation of Mycobacterium avium complex from M. tuberculosis and the long beaded forms of Mycobacterium gordonae from M. kansasii. Mycobacterium asiaticum and Mycobacterium szulgai, which rarely occur, are genetically related to M. kansasii and morphologically difficult to distinguish. In defined circumstances, serpentine cording and cross-barring can be used for rapid presumptive identification of M. tuberculosis and M. kansasii, respectively, and as guides for initial probe selection to reduce costs.  (+info)

In vivo administration of mycobacterial cord factor (Trehalose 6, 6'-dimycolate) can induce lung and liver granulomas and thymic atrophy in rabbits. (4/135)

Trehalose 6,6'-dimycolate (TDM) is a cell surface molecule of Mycobacterium tuberculosis. TDM induced a loss of body weight and prominent granulomas in the liver and lungs by the intravenous injection of TDM into rabbits. TDM also induced atrophy of the thymus and spleen due to apoptosis. By contrast, sulfolipid (2,3,6, 6'-tetraacyl trehalose 2'-sulfate) induced neither toxicity, nor granuloma formation, nor atrophy of the thymus and spleen. In rabbits the histopathological changes were more dramatic than in mice. The rabbit model may be more sensitive and may provide more information on the beneficial or pathological effects of TDM.  (+info)

How to establish a lasting relationship with your host: lessons learned from Mycobacterium spp. (5/135)

Mycobacterium spp. enjoy an intracellular lifestyle that is fatal to most microorganisms. Bacilli persist and multiply within mononuclear phagocytes in the face of defences ranging from toxic oxygen and nitrogen radicals, acidic proteases and bactericidal peptides. Uptake of Mycobacterium by phagocytes results in the de novo formation of a phagosome, which is manipulated by the pathogen to accommodate its needs for intracellular survival and replication. The present review describes the intracellular compartment occupied by Mycobacterium spp. and presents current ideas on how mycobacteria may establish this niche, placing special emphasis on the involvement of mycobacterial cell wall lipids.  (+info)

Trehalose 6,6'-dimycolate (cord factor) of Mycobacterium tuberculosis induces corneal angiogenesis in rats. (6/135)

Neovascularization or angiogenesis is required for the progression of chronic inflammation. The mechanism of inflammatory neovascularization in tuberculosis remains unknown. Trehalose 6, 6'-dimycolate (TDM) purified from Mycobacterium tuberculosis was injected into rat corneas. TDM challenge provoked a local granulomatous response in association with neovascularization. Neovascularization was seen within a few days after the challenge, with the extent of neovascularization being dose dependent, although granulomatous lesions developed 14 days after the challenge. Cytokines, including tumor necrosis factor alpha (TNF-alpha), interleukin-8 (IL-8), IL-1beta, and vascular endothelial growth factor (VEGF), were found in lesions at the early stage (within a few days after the challenge) and were detectable until day 21. Neovascularization was inhibited substantially by neutralizing antibodies to VEGF and IL-8 but not IL-1beta. Treatment with anti-TNF-alpha antibodies resulted in partial inhibition. TDM possesses pleiotropic activities, and the cytokine network plays an important role in the process of neovascularization.  (+info)

New diagnostic approach for ocular tuberculosis by ELISA using the cord factor as antigen. (7/135)

BACKGROUND/AIMS: Diagnosis of ocular tuberculosis is difficult, particularly the retinal vasculitis type, because most cases occur without concurrent active pulmonary tuberculosis. Recently, it has been reported that detection of antibodies against purified cord factor (trehalose-6,6'-dimycolate, TDM), the best studied, most antigenic, and most abundant cell wall component of tubercule bacilli, is very useful for rapid serodiagnosis of pulmonary tuberculosis. In this study, an attempt was made to evaluate whether the detection of anticord factor antibody is also useful for diagnosis of ocular tuberculosis and the necessity of antituberculous therapy for tuberculous retinochoroiditis was discussed. METHODS: Cases consisted of 15 patients with uveitis and retinal vasculitis, nine patients with presumed ocular tuberculosis, three patients with sarcoidosis, and three patients with Behcet's disease. IgG antibodies against purified cord factor prepared from Mycobacterium tuberculosis H37Rv were detected by enzyme linked immunosorbent assay. RESULTS: All cases of clinically presumed ocular tuberculosis were positive, whereas all of the cases of sarcoidosis or Behcet's disease were negative for anticord factor antibodies. When the anticord factor antibody titres were compared on the basis of the presence or absence of previous antituberculosis chemotherapy, the mean anticord factor antibody titre of the untreated group showed a tendency to be higher than in the treated group, but not significantly (p=0.07). CONCLUSIONS: The detection of anticord factor antibody may be useful to support the diagnosis of ocular tuberculosis. Additionally, a positive result for anticord factor antibody may indicate that tubercule bacilli are present in some organ(s) of the patient even in the absence of active systemic disease.  (+info)

Trehalose 6,6'-dimycolate (cord factor) of Mycobacterium tuberculosis induces foreign-body- and hypersensitivity-type granulomas in mice. (8/135)

Granulomatous inflammation is characterized morphologically by a compact organized collection of macrophages and their derivatives. It is classified as either a hypersensitivity type or a foreign-body type. Lipid components of the Mycobacterium tuberculosis cell wall participate in the pathogenesis of infection. Strains of M. tuberculosis have cord factor (trehalose 6,6'-dimycolate [TDM]) on their surface. To clarify host responses to TDM, including immunogenicity and pathogenicity, we have analyzed the footpad reaction, histopathology, and cytokine profiles of experimental granulomatous lesions in immunized and unimmunized mice challenged with TDM. In the present study, we have demonstrated for the first time that TDM can induce both foreign-body-type (nonimmune) and hypersensitivity-type (immune) granulomas by acting as a nonspecific irritant and T-cell-dependent antigen. Immunized mice challenged with TDM developed more severe lesions than unimmunized mice. At the active lesion, we found monocyte chemotactic, proinflammatory, and immunoregulatory cytokines. The level was enhanced in immunized mice challenged with TDM. This result implies that both nonimmune and immune mechanisms participate in granulomatous inflammation induced by mycobacterial infection. Taken together with a previous report, this study shows that TDM is a pleiotropic molecule against the host and plays an important role in the pathogenesis of tuberculosis.  (+info)

Cord factors are a group of glycolipids that are found on the surface of mycobacteria, including Mycobacterium tuberculosis, which is the bacterium that causes tuberculosis. These cord factors are called "cord factors" because they help to form characteristic "cords" or cable-like structures when mycobacteria grow in clumps.

Cord factors contribute to the virulence of mycobacteria by inhibiting the ability of certain immune cells, such as macrophages, to destroy the bacteria. They do this by preventing the fusion of lysosomes (which contain enzymes that can break down and kill the bacteria) with phagosomes (the compartments in which the bacteria are contained within the macrophage). This allows the mycobacteria to survive and replicate inside the host cells, leading to the development of tuberculosis.

Cord factors have also been shown to induce the production of pro-inflammatory cytokines, which can contribute to tissue damage and the pathogenesis of tuberculosis. Therefore, cord factors are an important target for the development of new therapies and vaccines against tuberculosis.

Glycolipids are a type of lipid (fat) molecule that contain one or more sugar molecules attached to them. They are important components of cell membranes, where they play a role in cell recognition and signaling. Glycolipids are also found on the surface of some viruses and bacteria, where they can be recognized by the immune system as foreign invaders.

There are several different types of glycolipids, including cerebrosides, gangliosides, and globosides. These molecules differ in the number and type of sugar molecules they contain, as well as the structure of their lipid tails. Glycolipids are synthesized in the endoplasmic reticulum and Golgi apparatus of cells, and they are transported to the cell membrane through vesicles.

Abnormalities in glycolipid metabolism or structure have been implicated in a number of diseases, including certain types of cancer, neurological disorders, and autoimmune diseases. For example, mutations in genes involved in the synthesis of glycolipids can lead to conditions such as Tay-Sachs disease and Gaucher's disease, which are characterized by the accumulation of abnormal glycolipids in cells.

Trehalose is a type of disaccharide, which is a sugar made up of two monosaccharides. It consists of two glucose molecules joined together in a way that makes it more stable and resistant to breakdown by enzymes and heat. This property allows trehalose to be used as a protectant for biological materials during freeze-drying and storage, as well as a food additive as a sweetener and preservative.

Trehalose is found naturally in some plants, fungi, insects, and microorganisms, where it serves as a source of energy and protection against environmental stresses such as drought, heat, and cold. In recent years, there has been interest in the potential therapeutic uses of trehalose for various medical conditions, including neurodegenerative diseases, diabetes, and cancer.

Medically speaking, trehalose may be used in some pharmaceutical formulations as an excipient or stabilizer, and it is also being investigated as a potential therapeutic agent for various diseases. However, its use as a medical treatment is still not widely established, and further research is needed to determine its safety and efficacy.

The spinal cord is a major part of the nervous system, extending from the brainstem and continuing down to the lower back. It is a slender, tubular bundle of nerve fibers (axons) and support cells (glial cells) that carries signals between the brain and the rest of the body. The spinal cord primarily serves as a conduit for motor information, which travels from the brain to the muscles, and sensory information, which travels from the body to the brain. It also contains neurons that can independently process and respond to information within the spinal cord without direct input from the brain.

The spinal cord is protected by the bony vertebral column (spine) and is divided into 31 segments: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each segment corresponds to a specific region of the body and gives rise to pairs of spinal nerves that exit through the intervertebral foramina at each level.

The spinal cord is responsible for several vital functions, including:

1. Reflexes: Simple reflex actions, such as the withdrawal reflex when touching a hot surface, are mediated by the spinal cord without involving the brain.
2. Muscle control: The spinal cord carries motor signals from the brain to the muscles, enabling voluntary movement and muscle tone regulation.
3. Sensory perception: The spinal cord transmits sensory information, such as touch, temperature, pain, and vibration, from the body to the brain for processing and awareness.
4. Autonomic functions: The sympathetic and parasympathetic divisions of the autonomic nervous system originate in the thoracolumbar and sacral regions of the spinal cord, respectively, controlling involuntary physiological responses like heart rate, blood pressure, digestion, and respiration.

Damage to the spinal cord can result in various degrees of paralysis or loss of sensation below the level of injury, depending on the severity and location of the damage.

"Mycobacterium bovis" is a species of slow-growing, aerobic, gram-positive bacteria in the family Mycobacteriaceae. It is the causative agent of tuberculosis in cattle and other animals, and can also cause tuberculosis in humans, particularly in those who come into contact with infected animals or consume unpasteurized dairy products from infected cows. The bacteria are resistant to many common disinfectants and survive for long periods in a dormant state, making them difficult to eradicate from the environment. "Mycobacterium bovis" is closely related to "Mycobacterium tuberculosis," the bacterium that causes tuberculosis in humans, and both species share many genetic and biochemical characteristics.

A granuloma is a small, nodular inflammatory lesion that occurs in various tissues in response to chronic infection, foreign body reaction, or autoimmune conditions. Histologically, it is characterized by the presence of epithelioid macrophages, which are specialized immune cells with enlarged nuclei and abundant cytoplasm, often arranged in a palisading pattern around a central area containing necrotic debris, microorganisms, or foreign material.

Granulomas can be found in various medical conditions such as tuberculosis, sarcoidosis, fungal infections, and certain autoimmune disorders like Crohn's disease. The formation of granulomas is a complex process involving both innate and adaptive immune responses, which aim to contain and eliminate the offending agent while minimizing tissue damage.

A granuloma in the respiratory tract refers to a small nodular lesion that forms in the lung tissue due to an ongoing immune response. It is typically composed of macrophages, lymphocytes, and other inflammatory cells that cluster together around a foreign substance or organism that the body cannot eliminate.

Granulomas can form in response to various stimuli, including infectious agents such as mycobacteria (tuberculosis, nontuberculous mycobacteria), fungi, and parasites, as well as non-infectious causes like inhaled particles (e.g., silica, beryllium) or autoimmune diseases (e.g., sarcoidosis).

These lesions can cause damage to the lung tissue over time, leading to symptoms such as cough, shortness of breath, chest pain, and fatigue. Diagnosis often involves imaging studies like chest X-rays or CT scans, followed by biopsy and microscopic examination to confirm the presence of granulomas and identify the underlying cause. Treatment depends on the underlying cause but may include antibiotics, corticosteroids, or other immunosuppressive medications.

'Mycobacterium tuberculosis' is a species of slow-growing, aerobic, gram-positive bacteria that demonstrates acid-fastness. It is the primary causative agent of tuberculosis (TB) in humans. This bacterium has a complex cell wall rich in lipids, including mycolic acids, which provides a hydrophobic barrier and makes it resistant to many conventional antibiotics. The ability of M. tuberculosis to survive within host macrophages and resist the immune response contributes to its pathogenicity and the difficulty in treating TB infections.

M. tuberculosis is typically transmitted through inhalation of infectious droplets containing the bacteria, which primarily targets the lungs but can spread to other parts of the body (extrapulmonary TB). The infection may result in a spectrum of clinical manifestations, ranging from latent TB infection (LTBI) to active disease. LTBI represents a dormant state where individuals are infected with M. tuberculosis but do not show symptoms and cannot transmit the bacteria. However, they remain at risk of developing active TB throughout their lifetime, especially if their immune system becomes compromised.

Effective prevention and control strategies for TB rely on early detection, treatment, and public health interventions to limit transmission. The current first-line treatments for drug-susceptible TB include a combination of isoniazid, rifampin, ethambutol, and pyrazinamide for at least six months. Multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of M. tuberculosis present significant challenges in TB control and require more complex treatment regimens.

I believe there might be a slight confusion in your question. Sulfuric acid is not a medical term, but instead a chemical compound with the formula H2SO4. It's one of the most important industrial chemicals, being a strong mineral acid with numerous applications.

If you are asking for a definition related to human health or medicine, I can tell you that sulfuric acid has no physiological role in humans. Exposure to sulfuric acid can cause irritation and burns to the skin, eyes, and respiratory tract. Prolonged exposure may lead to more severe health issues. However, it is not a term typically used in medical diagnoses or treatments.

Disaccharides are a type of carbohydrate that is made up of two monosaccharide units bonded together. Monosaccharides are simple sugars, such as glucose, fructose, or galactose. When two monosaccharides are joined together through a condensation reaction, they form a disaccharide.

The most common disaccharides include:

* Sucrose (table sugar), which is composed of one glucose molecule and one fructose molecule.
* Lactose (milk sugar), which is composed of one glucose molecule and one galactose molecule.
* Maltose (malt sugar), which is composed of two glucose molecules.

Disaccharides are broken down into their component monosaccharides during digestion by enzymes called disaccharidases, which are located in the brush border of the small intestine. These enzymes catalyze the hydrolysis of the glycosidic bond that links the two monosaccharides together, releasing them to be absorbed into the bloodstream and used for energy.

Disorders of disaccharide digestion and absorption can lead to various symptoms, such as bloating, diarrhea, and abdominal pain. For example, lactose intolerance is a common condition in which individuals lack sufficient levels of the enzyme lactase, leading to an inability to properly digest lactose and resulting in gastrointestinal symptoms.

Spinal cord injuries (SCI) refer to damage to the spinal cord that results in a loss of function, such as mobility or feeling. This injury can be caused by direct trauma to the spine or by indirect damage resulting from disease or degeneration of surrounding bones, tissues, or blood vessels. The location and severity of the injury on the spinal cord will determine which parts of the body are affected and to what extent.

The effects of SCI can range from mild sensory changes to severe paralysis, including loss of motor function, autonomic dysfunction, and possible changes in sensation, strength, and reflexes below the level of injury. These injuries are typically classified as complete or incomplete, depending on whether there is any remaining function below the level of injury.

Immediate medical attention is crucial for spinal cord injuries to prevent further damage and improve the chances of recovery. Treatment usually involves immobilization of the spine, medications to reduce swelling and pressure, surgery to stabilize the spine, and rehabilitation to help regain lost function. Despite advances in treatment, SCI can have a significant impact on a person's quality of life and ability to perform daily activities.

Oxidative phosphorylation is the metabolic process by which cells use enzymes to generate energy in the form of adenosine triphosphate (ATP) from the oxidation of nutrients, such as glucose or fatty acids. This process occurs in the inner mitochondrial membrane of eukaryotic cells and is facilitated by the electron transport chain, which consists of a series of protein complexes that transfer electrons from donor molecules to acceptor molecules. As the electrons are passed along the chain, they release energy that is used to pump protons across the membrane, creating a gradient. The ATP synthase enzyme then uses the flow of protons back across the membrane to generate ATP, which serves as the main energy currency for cellular processes.

Immunologic adjuvants are substances that are added to a vaccine to enhance the body's immune response to the antigens contained in the vaccine. They work by stimulating the immune system and promoting the production of antibodies and activating immune cells, such as T-cells and macrophages, which help to provide a stronger and more sustained immune response to the vaccine.

Immunologic adjuvants can be derived from various sources, including bacteria, viruses, and chemicals. Some common examples include aluminum salts (alum), oil-in-water emulsions (such as MF59), and bacterial components (such as lipopolysaccharide or LPS).

The use of immunologic adjuvants in vaccines can help to improve the efficacy of the vaccine, particularly for vaccines that contain weak or poorly immunogenic antigens. They can also help to reduce the amount of antigen needed in a vaccine, which can be beneficial for vaccines that are difficult or expensive to produce.

It's important to note that while adjuvants can enhance the immune response to a vaccine, they can also increase the risk of adverse reactions, such as inflammation and pain at the injection site. Therefore, the use of immunologic adjuvants must be carefully balanced against their potential benefits and risks.

Gamma-globulins are a type of protein found in the blood serum, specifically a class of immunoglobulins (antibodies) known as IgG. They are the most abundant type of antibody and provide long-term defense against bacterial and viral infections. Gamma-globulins can also be referred to as "gamma globulin" or "gamma immune globulins."

These proteins are produced by B cells, a type of white blood cell, in response to an antigen (a foreign substance that triggers an immune response). IgG gamma-globulins have the ability to cross the placenta and provide passive immunity to the fetus. They can be measured through various medical tests such as serum protein electrophoresis (SPEP) or immunoelectrophoresis, which are used to diagnose and monitor conditions related to immune system disorders, such as multiple myeloma or primary immunodeficiency diseases.

In addition, gamma-globulins can be administered therapeutically in the form of intravenous immunoglobulin (IVIG) to provide passive immunity for patients with immunodeficiencies, autoimmune disorders, or infectious diseases.

Mitochondrial swelling is a pathological change in the structure of mitochondria, which are the energy-producing organelles found in cells. This condition is characterized by an increase in the volume of the mitochondrial matrix, which is the space inside the mitochondrion that contains enzymes and other molecules involved in energy production.

Mitochondrial swelling can occur as a result of various cellular stressors, such as oxidative damage, calcium overload, or decreased levels of adenosine triphosphate (ATP), which is the primary energy currency of the cell. This swelling can lead to disruption of the mitochondrial membrane and release of cytochrome c, a protein involved in apoptosis or programmed cell death.

Mitochondrial swelling has been implicated in several diseases, including neurodegenerative disorders, ischemia-reperfusion injury, and drug toxicity. It can be observed under an electron microscope as part of an ultrastructural analysis of tissue samples or detected through biochemical assays that measure changes in mitochondrial membrane potential or matrix volume.

"Mycobacterium" is a genus of gram-positive, aerobic, rod-shaped bacteria that are characterized by their complex cell walls containing large amounts of lipids. This genus includes several species that are significant in human and animal health, most notably Mycobacterium tuberculosis, which causes tuberculosis, and Mycobacterium leprae, which causes leprosy. Other species of Mycobacterium can cause various diseases in humans, including skin and soft tissue infections, lung infections, and disseminated disease in immunocompromised individuals. These bacteria are often resistant to common disinfectants and antibiotics, making them difficult to treat.

Mycolic acids are complex, long-chain fatty acids that are a major component of the cell wall in mycobacteria, including the bacteria responsible for tuberculosis and leprosy. These acids contribute to the impermeability and resistance to chemical agents of the mycobacterial cell wall, making these organisms difficult to eradicate. Mycolic acids are unique to mycobacteria and some related actinomycetes, and their analysis can be useful in the identification and classification of these bacteria.

Nontuberculous mycobacteria (NTM) are a group of environmental mycobacteria that do not cause tuberculosis or leprosy. They can be found in water, soil, and other natural environments. Some people may become infected with NTM, leading to various diseases depending on the site of infection, such as lung disease (most common), skin and soft tissue infections, lymphadenitis, and disseminated disease.

The clinical significance of NTM isolation is not always clear, as colonization without active infection can occur. Diagnosis typically requires a combination of clinical, radiological, microbiological, and sometimes molecular evidence to confirm the presence of active infection. Treatment usually involves multiple antibiotics for an extended period, depending on the species involved and the severity of disease.

Bovine Serum Albumin (BSA) is not a medical term per se, but a biochemical term. It is widely used in medical and biological research. Here's the definition:

Bovine Serum Albumin is a serum albumin protein derived from cows. It is often used as a stabilizer, an emulsifier, or a protein source in various laboratory and industrial applications, including biochemical experiments, cell culture media, and diagnostic kits. BSA has a high solubility in water and can bind to many different types of molecules, making it useful for preventing unwanted interactions between components in a solution. It also has a consistent composition and is relatively inexpensive compared to human serum albumin, which are factors that contribute to its widespread use.

I'd be happy to help! However, I believe there might be a slight misunderstanding in your question. Mitochondria are organelles found in the cells of all complex living organisms, including humans, while the liver is a large, solid organ located in the upper right portion of the abdomen. They don't have a medical definition together. I can certainly provide you with separate definitions for each:

1. Mitochondria: These are double-membrane-bound cellular organelles that generate most of the chemical energy needed to power the cell's biochemical reactions. Commonly known as the "powerhouse of the cell," mitochondria convert organic substrates, such as glucose, fatty acids, and amino acids, into adenosine triphosphate (ATP) through a process called oxidative phosphorylation. Mitochondria are dynamic structures that can change their shape, size, and number through fission (division) and fusion (merging) processes. They play essential roles in various cellular functions, including calcium signaling, apoptosis (programmed cell death), and the regulation of cellular metabolism.

2. Liver: The liver is a large, lobulated organ that lies mainly in the upper right portion of the abdominal cavity, just below the diaphragm. It plays a crucial role in various physiological functions, such as detoxification, protein synthesis, metabolism, and nutrient storage. The liver is responsible for removing toxins from the bloodstream, producing bile to aid in digestion, regulating glucose levels, synthesizing plasma proteins, and storing glycogen, vitamins, and minerals. It also contributes to the metabolism of carbohydrates, lipids, and amino acids, helping maintain energy homeostasis in the body.

I hope this clarifies any confusion! If you have any further questions or need more information, please don't hesitate to ask.

Paraplegia is a medical condition characterized by partial or complete loss of motor function and sensation in the lower extremities, typically affecting both legs. This results from damage to the spinal cord, often due to trauma such as accidents, falls, or gunshot wounds, or from diseases like spina bifida, polio, or tumors. The specific area and extent of the injury on the spinal cord determine the severity and location of paralysis. Individuals with paraplegia may require assistive devices for mobility, such as wheelchairs, and may face various health challenges, including pressure sores, urinary tract infections, and chronic pain.

I'm sorry for any confusion, but "Sports" is not a medical term. It refers to physical activities that are governed by a set of rules and often engaged in competitively. However, there are fields such as Sports Medicine and Exercise Science that deal with various aspects of physical activity, fitness, and sports-related injuries or conditions. If you have any questions related to these areas, I'd be happy to try to help!

Sports medicine is a branch of healthcare that deals with the prevention, diagnosis, treatment, and rehabilitation of injuries and illnesses related to sports and exercise. It involves a multidisciplinary approach, including medical doctors, orthopedic surgeons, physical therapists, athletic trainers, and other healthcare professionals who work together to help athletes and active individuals return to their desired level of activity as quickly and safely as possible.

The scope of sports medicine includes the management of acute injuries such as sprains, strains, fractures, and dislocations, as well as chronic overuse injuries like tendinitis, stress fractures, and bursitis. It also addresses medical conditions that can affect athletic performance or overall health, including concussions, asthma, diabetes, and cardiovascular disease.

Preventive care is an essential component of sports medicine, with healthcare providers educating athletes on proper warm-up and cool-down techniques, nutrition, hydration, and injury prevention strategies to reduce the risk of future injuries. Additionally, sports medicine professionals may work with coaches, trainers, and athletes to develop safe training programs that promote optimal performance while minimizing the risk of injury.

Doping in sports is the use of prohibited substances or methods to improve athletic performance. The World Anti-Doping Agency (WADA) defines doping as "the occurrence of one or more of the following anti-doping rule violations":

1. Presence of a prohibited substance in an athlete's sample
2. Use or attempted use of a prohibited substance or method
3. Evading, refusing, or failing to submit to sample collection
4. Whereabouts failures (three missed tests or filing failures within a 12-month period)
5. Tampering or attempted tampering with any part of the doping control process
6. Possession, trafficking, or administration of a prohibited substance or method
7. Complicity in an anti-doping rule violation
8. Prohibited association with a person who has been serving a period of ineligibility for an anti-doping rule violation

Doping is considered unethical and harmful to the integrity of sports, as it provides an unfair advantage to those who engage in it. It can also have serious health consequences for athletes. Various international and national organizations, including WADA and the United States Anti-Doping Agency (USADA), work to prevent doping in sports through education, testing, and enforcement of anti-doping rules.

Athletic injuries are damages or injuries to the body that occur while participating in sports, physical activities, or exercise. These injuries can be caused by a variety of factors, including:

1. Trauma: Direct blows, falls, collisions, or crushing injuries can cause fractures, dislocations, contusions, lacerations, or concussions.
2. Overuse: Repetitive motions or stress on a particular body part can lead to injuries such as tendonitis, stress fractures, or muscle strains.
3. Poor technique: Using incorrect form or technique during exercise or sports can put additional stress on muscles, joints, and ligaments, leading to injury.
4. Inadequate warm-up or cool-down: Failing to properly prepare the body for physical activity or neglecting to cool down afterwards can increase the risk of injury.
5. Lack of fitness or flexibility: Insufficient strength, endurance, or flexibility can make individuals more susceptible to injuries during sports and exercise.
6. Environmental factors: Extreme weather conditions, poor field or court surfaces, or inadequate equipment can contribute to the risk of athletic injuries.

Common athletic injuries include ankle sprains, knee injuries, shoulder dislocations, tennis elbow, shin splints, and concussions. Proper training, warm-up and cool-down routines, use of appropriate protective gear, and attention to technique can help prevent many athletic injuries.

I'm sorry for any confusion, but "Fitness Centers" is not a term that has a specific medical definition. It generally refers to facilities where people go to engage in physical activity and exercise, such as gyms, health clubs, or fitness studios. However, the term itself is not a medical concept. If you have any questions related to health, fitness, or exercise that do have a medical context, I'd be happy to try to help answer those!

I'm sorry for any confusion, but "Sports Equipment" is not a term that typically has a medical definition. It generally refers to the physical items or gear used in sports and athletic activities, such as balls, bats, helmets, protective pads, etc. If you're looking for a term related to sports that has a medical definition, I'd be happy to help with that!

The chord factor called the "fifth" (pitch name "G") is represented in voice 2 (shown in red). The chord factor that is in the ... In music, a factor or chord factor is a member or component of a chord. These are named root, third, fifth, sixth, seventh, ... Chord factors are taken into consideration in voicing and voice leading. A chord contains exactly as many factors as it ... The illustration shows the theoretical construction of a C13 chord having seven chord factors, with the "extended" chord ...
In music, the third factor of a chord is the note or pitch two scale degrees above the root or tonal center. When the third is ... In jazz chords and theory, the third is required due to it determining chord quality. The third in both major and augmented ... chords is major (E♮ in C) and the third in both minor and diminished chords is minor (E♭ in C). In music and music theory, a ... tenth is the note ten scale degrees from the root of a chord and also the interval between the root and the tenth. Since there ...
ISBN 978-0-07-310188-0. (Pages using the Phonos extension, Chord factors, Eleventh chords). ... also known as the jazz sus chord). Elektra chord Jazz chord Bridge chord Smith, Johnny (1980). Mel Bay's Complete Johnny Smith ... an eleventh chord is a chord that contains the tertian extension of the eleventh. Typically found in jazz, an eleventh chord ... In the common practice period, the root, 7th, 9th, and 11th are the most common factors present in the V11 chord, with the 3rd ...
93 Conference on Human Factors in Computing Systems: 88-94. Lytton, Charlotte (11 January 2022). "This could help you type at ... A keyset or chorded keyboard (also called a chorded keyset, chord keyboard or chording keyboard) is a computer input device ... "Chorded keyboard , Art of Chording". "PIC-Key chorded keyboard". Cuddlepuddle. Retrieved 2011-10-24. "Spiffchorder Project". ... Unlike pressing a chord on a piano, the chord is recognized only after all the keys or mouse buttons are released. Since ...
Yerlikaya G, Pils S, Springer S, Chalubinski K, Ott J (2015). "Velamentous cord insertion as a risk factor for obstetric ... The exact cause of velamentous cord insertion is unknown, although risk factors include nulliparity, the use of assisted ... The following have been identified as risk factors for velamentous cord insertion: Nulliparity History of infertility The use ... Velamentous cord insertion is a complication of pregnancy where the umbilical cord is inserted in the fetal membranes. It is a ...
Prevention and treatment of these modifiable risk factors could reduce the likelihood of spinal cord stroke. As the high ... Unlike anterior spinal cord stroke, motor functions are not handicapped in posterior spinal cord stroke. In central spinal cord ... Spinal cord stroke is a rare type of stroke with compromised blood flow to any region of spinal cord owing to occlusion or ... Preventions of the disease include decreasing the risk factors and maintaining enough spinal cord perfusion pressure during and ...
A review of the factors influencing walking recovery after spinal cord injury". Frontiers in Human Neuroscience. 8: 141. doi: ... A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function. Symptoms ... Thus it is not a true spinal cord syndrome since it is nerve roots that are damaged and not the cord itself; however, it is ... Central cord syndrome, almost always resulting from damage to the cervical spinal cord, is characterized by weakness in the ...
... and inflammatory factors may also act as predisposing or aggravating factors. Inflammatory factors may include allergies, ... Predisposing factors include profession, gender, dehydration, respiratory infection, and other inflammatory factors. For ... Vocal cord nodules are bilaterally symmetrical benign white masses that form at the midpoint of the vocal folds. Although ... There are several factors that may predispose an individual to vocal fold nodules. Activities or professions that may ...
When stem cells are injected in the area of damage in the spinal cord, they secrete neurotrophic factors, and these factors ... Spinal cord injury research seeks new ways to cure or treat spinal cord injury in order to lessen the debilitating effects of ... Spinal cord implants, such as e-dura implants, designed for implantation on the surface of the spinal cord, are being studied ... The theory behind the new spinal cord stimulator is that in certain cases of spinal cord injury the spinal nerves between the ...
Because the disruption of the BSCB is a major exacerbating factor in SCIs, reestablishment of normal function is critical to ... Blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced MRI. NMR Biomed 2009;22: ... Because of its function as a protective barrier for the spinal cord, disruption of the BSCB exposes spinal cord tissue to ... The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord ...
Martin Popoff (2021). Power Chord Press (ed.). Wheels of Steel - the explosive early years of the NWOBHM p.193. Canada. ISBN ... 978-1912782185.{{cite book}}: CS1 maint: location missing publisher (link) Dome, Malcolm (2014). "The Ex-Factor". Classic Rock ...
However, factors such as age, preexisting conditions, and extent of injury will affect the recovery process. CCS is ... Spinal cord injury Anterior cord syndrome Posterior cord syndrome Brown-Séquard syndrome Quencer RM, Bunge RP, Egnor M, Green ... Central cord syndrome (CCS) is the most common form of cervical spinal cord injury. It is characterized by loss of power and ... Historically, spinal cord damage was believed to originate from concussion or contusion of the cord with stasis of axoplasmic ...
"Prognostic factors responsible for survival in sex cord stromal tumors of the ovary?A multivariate analysis". Gynecologic ... Sex cord-gonadal stromal tumour is a group of tumors derived from the stromal component of the ovary and testis, which ... Sex cord tumour with annular tubules, abbreviated SCTAT. These are rare tumours that may be sporadic or associated with Peutz- ... Sex cord Stroma of ovary Maoz, Asaf; Matsuo, Koji; Ciccone, Marcia A.; Matsuzaki, Shinya; Klar, Maximilian; Roman, Lynda D.; ...
In modern popular music, a sixth chord is any triad with an added sixth above the root as a chord factor. This was ... considers this chord to be the utonality to the dominant seventh chord. The minor flat sixth chord is a minor triad and the ... one would have an added sixth chord (C-E-G-B♭-D′-F′-A′ minus B♭-D′-F′ = C-E-G-A). 6/9 chord thirteenth chord Music: The ... These are the same notes as those of an A minor seventh chord - whether such a chord should be regarded as an added sixth chord ...
"Risk Factors for Brain and Spinal Cord Tumors". www.cancer.org. Retrieved 2019-06-28. "Signs and Symptoms of Adult Brain and ... A central nervous system tumor (CNS tumor) is an abnormal growth of cells from the tissues of the brain or spinal cord. CNS ... A few risk factors are known, including radiation exposure, genetic disorder, a family history of CNS tumors, immunodeficiency ... Tumors located in the spinal cord usually have symptoms that start with back pain that spreads towards the arms or legs. These ...
Magnetic Resonance Imaging Prognostic Factors". World Neurosurgery. 99: 192-199. doi:10.1016/j.wneu.2016.12.005. PMID 27979630 ... Spinal cord injury without radiographic abnormality (SCIWORA) is symptoms of a spinal cord injury (SCI) with no evidence of ... A number of underlying mechanisms are proposed including spinal cord contusion, injury to the blood supply to the spinal cord, ... Historical literature regarding spinal cord concussion, spinal cord contusion and hyperextension/hyperflexion injuries to the ...
The seventh factor helps to define the chord as an extended chord (and not an added note chord), and also adds to the texture. ... Added tone chord Elektra chord Hendrix chord Tristan chord Upper structure triad for an examination of extended harmony with ... Extended Chords on Guitar by fretjam Extended Chords on Piano by pianogroove Chord Construction by guiterthinker (Pages using ... Technically a fifteenth chord "Chord Extensions 9ths, 11ths & 13ths , Extended Jazz Piano Chords". PianoGroove.com. Retrieved ...
... and other sex cord-stromal tumors Mixed sex cord-stromal tumor Signet ring stromal tumor Myoid gonadal stromal tumor Sex cord- ... Risk factors include an undescended testis, family history of the disease, and previous history of testicular cancer. More than ... A major risk factor for the development of testis cancer is cryptorchidism (undescended testicles). It is generally believed ... Other risk factors include inguinal hernias, Klinefelter syndrome, and mumps orchitis. Physical activity is associated with ...
"On Top of the World Chords". ultimate-guitar.com. Retrieved 3 April 2013. "- Watch The X-Factor Clips - Official site". "'On ... The song incorporates the chord progression of C-F-C-Dm in the verses, and F-C-G-Dm in the chorus and bridge, with the pre- ... Imagine Dragons performed the song live on the Australian version of The X Factor in 2013. "On Top of the World" was licensed ...
For instance a minor chord that includes a major second factor holds a great deal more dramatic tension due to the very close ... An added tone chord, or added note chord, is a non-tertian chord composed of a triad and an extra "added" note. Any tone that ... Songs with a 7♯9 chord include "Purple Haze" and "Boogie Nights". Examples of the added-second chord or added-ninth chord ( ... Igor Stravinsky's polytonal Symphony of Psalms contains many added tone chords. A mixed third chord, also split-third chord, ...
As the neural tube begins to develop, the notochord begins to secrete a factor known as Sonic hedgehog (SHH). As a result, the ... Spinal Cord Sectional Anatomy. Animation in the reference. Diagrams of the spinal cord. Cross-section through the spinal cord ... The spinal cord is also covered by meninges and enclosed by the neural arches. Together, the brain and spinal cord make up the ... The spinal cord is made from part of the neural tube during development. There are four stages of the spinal cord that arises ...
1955-56 spinal cord injury information network - info sheet 12 Simonsen, L.L., Sonne-Holm, S., Krasheninnikoff, M., Engberg, A. ... Incidence and risk factors". Injury, Int. J. Care Injured 38: 1146-1150. Cipriano, C.A., Pill, S.G., Keenan, M.A. (2009). " ... uptake around the knees or the ankles in a patient with a very recent spinal cord injury. It is not clear exactly what this ... jaw or in patients after spinal cord trauma. Single dose radiation therapy is well tolerated and is cost effective, without an ...
Prolapsed cord can only happen after the membranes have ruptured. The umbilical cord delivers before the presenting part of the ... Some unknown factors cause vascular damage in the endothelium, causing hypertension. If severe, it progresses to eclampsia, ... If the foetus is not delivered within minutes, or the pressure taken off the cord, the foetus dies. Obstetrical hemorrhage may ... "Umbilical Cord Prolapse: Causes, Diagnosis & Management". Cleveland Clinic. Retrieved 2022-04-30. Smith JR (2022-04-01). " ...
Former member of X-Factor on Krakoa. Currently deceased. Radian (Christian Cord) - Depowered as a result of M-Day. Redneck ( ... Tattoo (Christine Cord) - Depowered as a result of M-Day. Currently deceased. Mentored by Rogue. Boggart (Robin Wise) - ... Current member of X-Factor on Krakoa. Vulcan (Gabriel Summers) - Omega-level mutant. Trained to rescue the original X-Men team ... Later murdered but resurrected on Krakoa, serving with X-Factor. Elixir (Josh Foley) - Omega-level mutant; current member of ...
Additionally, genetic factors cause variations between members of the same sex, with males' and females' voices being ... contemporary writers opt for the nonstandard chords instead of cords 49% of the time. The cords spelling is also standard in ... The human vocal cords are roughly 12 - 24 mm in length, and 3-5 mm thick. Histologically, the human vocal cords are a laminated ... The vocal folds are commonly referred to as vocal cords, and less commonly as vocal flaps or vocal bands. The term vocal cords ...
The fact that the staff was used more as a defensive weapon was a determining factor in the tests, and the taiaha was given the ... The bat broke a pig's spine with a single swing, which was clocked at over 100 mph, breaking five segments of the spinal cord. ... A second strike broke the spinal cord and a third completely shattered the skull, removing all brain matter from the brainpan. ... The iklwa pierced a lung and severed the carcase's spinal cord. The weapon also penetrated a sample of unriveted chainmail and ...
Mendell discovered the property of windup pain in the spinal cord. Windup is the property of C-fibres in the peripheral nerves ... Within this, there was also a focus in brain-derived neurotrophic factor (BDNF) and their sensitizing effect on specific ... He has been a part of the search for novel treatments for spinal cord injuries and continues to study neurotrophins to ... In more recent times, Mendell's research has been focused partly on spinal cord injury and the use of neurotophins as a ...
The inextensible belt and the radial casing cords were the combined factors which gave the Cinturato tyre its special ... The tread and belt are in effect the rim; the 90-degree or radial cord plies are the spokes; and the bead is the hub. ... the tyre was composed of two or three carcass plies of cords laid at an angle of 90 degrees to the beads, and a belt of several ...
Equivalent activity limitation to person with complete cord injury at cord level C7-8" The International Paralympic Committee ... Sportspeople with muscular dystrophy in this class have a number of factors that can make sports participation difficult. This ... People with spinal cord injuries compete in this class, including F2 sportspeople. This is wheelchair sport classification that ... The Australian Paralympic Committee defines this classification as being for people with "Damage to spinal cord in the higher ...
... (vascular disease of the spinal cord) refers to an abnormality of the spinal cord in regard to its blood ... Other factors such as thrombosis or arachnoiditis can be involved. A bruit (unusual blood sounds) may be heard overlying the ... Sensory loss to pain and temperature also occurs up to the level of damage on the spinal cord, as damage to different areas ... Myelography is used to confirm the diagnosis of AVMs and it shows 'snake-like' vessels on the cord's surface. If the myelogram ...
The chord factor called the "fifth" (pitch name "G") is represented in voice 2 (shown in red). The chord factor that is in the ... In music, a factor or chord factor is a member or component of a chord. These are named root, third, fifth, sixth, seventh, ... Chord factors are taken into consideration in voicing and voice leading. A chord contains exactly as many factors as it ... The illustration shows the theoretical construction of a C13 chord having seven chord factors, with the "extended" chord ...
Cardiovascular risk factors. One study showed significant association between cardiovascular risk factors and fitness, similar ... Sports Participation by Individuals With Spinal Cord Injury * Sections Sports Participation by Individuals With Spinal Cord ... lipid profile and insulin sensitivity in early rehabilitation of spinal cord injured individuals. Spinal Cord. 2003 Dec. 41(12 ... An additional factor for the rapid growth of participation in sporting activities by those with paraplegia is the improvement ...
It may result from direct injury to the cord itself or indirectly from disease of the nearby bones, tissues, or blood vessels. ... It may result from direct injury to the cord itself or indirectly from disease of the nearby bones, tissues, or blood vessels. ... Spinal cord trauma is damage to the spinal cord. ... Spinal cord trauma is damage to the spinal cord. ... Risk factors include:. *Participating in risky physical activities. *Riding in or on high-speed vehicles ...
Letter: Charting a Path Forward: Factors Influencing Gender and Racial Disparities in Spinal Cord Injury Trials. Neurosurgery. ... Letter: Charting a Path Forward: Factors Influencing Gender and Racial Disparities in Spinal Cord Injury Trials. / Naik, Anant ... Letter : Charting a Path Forward: Factors Influencing Gender and Racial Disparities in Spinal Cord Injury Trials. In: ... title = "Letter: Charting a Path Forward: Factors Influencing Gender and Racial Disparities in Spinal Cord Injury Trials", ...
... and life satisfaction between admission to spinal cord injury inpatient rehabilitation and discharge; and to identify factors ... Biopsychosocial factors were examined as covariates of change. Results: On average, depressive symptoms, anxiety symptoms, and ... Longitudinal changes in psychological adaptation outcomes during spinal cord injury inpatient rehabilitation Rehabil Psychol. ...
In music, the third factor of a chord is the note or pitch two scale degrees above the root or tonal center. When the third is ... In jazz chords and theory, the third is required due to it determining chord quality. The third in both major and augmented ... chords is major (E♮ in C) and the third in both minor and diminished chords is minor (E♭ in C). In music and music theory, a ... tenth is the note ten scale degrees from the root of a chord and also the interval between the root and the tenth. Since there ...
... and dispenses extension cords and hoses without the use of springs, ratchets, or motorized mechanisms. It can hold a 100-foot ... 3 Factors To Consider When Mounting A Mini-Split Condenser. Popular Stories. ... It can hold a 100-foot length of cord and stores and protects the ends of cords when not in use, the company says. As the user ... As the user moves, the reel will travel behind the user and continue to dole out the exact amount of cord needed, states the ...
3m Cord - Available at Comms Express, Networking Reseller - Free Next Day Delivery ... The 2.8" color LCD with touchscreen provides a sharp and highly visible display of kWh, kW, Power Factor, Volt, Amp, ... The 2.8" color LCD with touchscreen provides a sharp and highly visible display of kWh, kW, Power Factor, Volt, Amp, ... Austin Hughes 1 Phase Intelligent W Series Horizontal PDU, C13/C19 Mixed Socket, 230V, 3m Cord. ...
We developed simple sign-based definitions of omphalitis and estimated incidence and risk factors for infection over a range of ... RESULTS: Nine thousand five hundred fifty cord assessments (in 1653 infants) were conducted. The proportion of affected infants ... Two definitions were examined for associations between infection and selected potential risk factors using multivariate ... Few community-based data exist on the frequency of cord infection signs in low resource settings, especially in Sub-Saharan ...
... vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord ... vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord ... vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord ...
Gy for metastatic epidural spinal cord compression (MESCC) in patients with poor, intermediate and favorable survival prognoses ... Prognostic factors for local control and survival after radiotherapy of metastatic spinal cord compression. J Clin Oncol. 2006; ... Rades, D., Conde-Moreno, A.J., Cacicedo, J. et al. 1x8 Gy versus 5x4 Gy for metastatic epidural spinal cord compression: a ... Metastatic epidural spinal cord compression (MESCC) is an oncologic emergency that is most often treated with radiotherapy (RT ...
Factor II deficiency is a very rare blood clotting disorder. It results in excessive or prolonged bleeding after an injury or ... In cases of severe factor II deficiency, symptoms may include:. *umbilical cord bleeding at birth ... Factor assays: These tests check the performance of specific factors to identify missing or poorly performing factors. ... factor IIa (thrombin). Factor IIa causes factor I (fibrinogen) to make the stringy protein fibrin. ...
Other risk factors for CP include low birthweight and prematurity. Thanks to modern medical advances, babies born prematurely ... Brain and Spinal Cord Injury Rehabilitation puts most families in crushing debt. Often, a lawsuit is the only way to finance it ... In addition, a condition known as Rh incompatibility is an increased risk factor for spastic diplegia and other forms of ...
Prevalence and risk factors of depressive symptoms in children and adolescents with juvenile idiopathic arthritis. ... HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop. ... Spinal Cord Stimulation Increases Chemoefficacy and Prevents Paclitaxel-Induced Pain via CX3CL1. ... Unrelieved chronic pain is considered a key factor contributing to the maintenance of alcohol use disorder (AUD). The ...
Accumulated chord length (mm). Voids counted. Mean chord length (mm). Voids per m. Specific surface (mm2/mm3). Spacing factor ( ... Accumulated chord length (mm). Voids counted. Mean chord length (mm). Voids per m. Specific surface (mm2/mm3). Spacing factor ( ... Figure 2. Relationship between the durability factor and spacing factor of mixes with Vinsol resin admixture (Set 1) or ... Table 2. The durability factor results for Set 1 (VR AEA) sorted by percent of fresh air content. Mix. Fresh air (%). ...
... small tears of the outer membrane of the spinal cord -- are a common occurrence in spinal surgery, and may lead to litigation. ... Cat Locomotion Could Unlock Better Human Spinal Cord Injury Treatment. Jan. 9, 2023 Cats always land on their feet, but what ... Research Brings Hope for Spinal Cord Injury Treatment. May 20, 2022 Scientists have shown an existing drug may reduce damage ... Durotomy: Common complication of spinal surgery, and an important factor in some malpractice cases. Date:. December 4, 2017. ...
Add in cord-cutting, which remains a big factor. In turn, media companies have started more direct-to-consumer streaming ...
... cruzi infection to their babies is considered key to accomplishing these factors. The evidence base to support screening ... Cord Blood Sample Screening for Evidence of Maternal Chagas Disease. Emerging Infectious Diseases. 2017;23(4):722-723. doi: ... Cord Blood Sample Screening for Evidence of Maternal Chagas Disease On This Page ... We do not know whether testing of cord blood samples was performed by another laboratory; only the ARC NTL was described in the ...
Cord factor bertanggung jawab atas serpentine cording. Cord factor bersifat toksik bagi sel mamalia dan penghambat migrasi ... Cord factor banyak diproduksi pada strain virulen M. tuberculosis. Wax-D dalam selubung sel adalah komponen utama dari Freunds ... Fraksi lipid dinding sel M. tuberculosis terdiri dari tiga komponen utama yaitu asam mikolat, cord factor dan wax-D. Asam ...
Other factors. Other causes of priapism include:. *A spider bite, scorpion sting or other toxic infections ... Neurogenic disorders, such as a spinal cord injury or syphilis. *Cancers involving the penis ...
Input Cord Location:. Horizontal. Outlet Form Factor:. Conventional Total Outlets:. 12. NEMA 5-20R Count:. 12. ...
There are many different factors in choosing an extension cord. You may need one for length or one to use with multiple devices ... Posted in Extension Cords, Wiring , Tagged extension cords, revisit. Are Extension Cords Safe For Permanent Use. Posted on ... This extension cord is potentially the best extension cord on the market today. It has a long and heavy duty cord to handle ... Purchase an extension cord identified as an outdoor extension cord.. Also, note that even outdoor extension cords built for use ...
Human-factors-engineering; Musculoskeletal-system; Overloading; Cumulative-trauma; Spinal-cord; Back-injuries; Pain-tolerance; ... Background: Cumulative spine loading has been a suspected risk factor for low back pain for many years, yet the measures that ... Biomechanics; Epidemiology; Surveillance-programs; Risk-analysis; Exposure-assessment; Body-mechanics; Risk-factors; Clinical- ...
A-5 Polynomials: Factoring A-6 Rational Expressions: Basic Operations Appendix A Review Appendix A Group Activity: Rational ... Chapter 8 Group Activity: Focal Chords Cumulative Review Exercise for Chapters 7 and 8 Appendix A BASIC ALGEBRA REVIEW A-1 ... The estimated amount of time this product will be on the market is based on a number of factors, including faculty input to ...
Differential ability of tissue factor antibody clones on detection of tissue factor in blood cells and microparticles ... Spinal Cord 2015 ARKIV / DOI. * Anne Landsem, Hilde Fure, Dorte Christiansen, Erik Waage Nielsen, Bjarne Østerud, Tom Eirik ... C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression ... Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood Springer Science+Business Media B ...
Spinal cord injury; SONs: Supraoptic nuclei; TSH: Thyrotropin; NT: Tissues of normal thyroid; TGF-β: Transforming growth factor ... Vascular endothelial growth factor A (VEGFA) acts as an important growth factor to contribute to angiogenesis. CREB3L1 can ... CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a ... Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis. FASEB J. 2021;35: ...
Prevention of Venous Thromboembolism in Individuals With Spinal Cord Injury (3rd Edition) ... These guidelines focus on stroke risk factors unique to or more common in women, as well as stroke prevention in women. ... Examines changes to the cardiovascular and coagulation system caused by acute spinal cord injury (SCI) and provides ... Prevention of Venous Thromboembolism in Individuals With Spinal Cord Injury (3rd Edition). CPG ...
29] confirmed that influenza is a risk factor for developing cleft palate like other lifestyle factors (gender, birthweight and ... Neural tube defects are congenital brain, spine, or spinal cord abnormalities. Many studies [44,45,46] have investigated the ... As the prognostic factor measurement was not carried out with PCR and the chances of recall bias were high, the overall risk of ... Risk factors of different congenital heart defects in Guangdong, China. Pediatr. Res. 2016, 79, 549-558. [Google Scholar] [ ...
Spinal Cord Stimulators segment to record considerable revenue. The brain implants market size from spinal cord stimulators may ... The surging popularity of neural implants to treat multiple sclerosis is another major factor driving the industry evolution. ... The robust adoption of spinal cord stimulators for significantly improving the quality of lives of patients by reducing pain ...
  • EBNA-LP-mutant EBVs established lymphoblastoid cell lines (LCLs) from adult B cells at reduced efficiency, but not from umbilical cord B cells, which died approximately two weeks after infection. (plos.org)
  • Incidence and Risk Factors for Newborn Umbilical Cord Infections on Pe" by Luke C. Mullany, Silvana Faillace et al. (gwu.edu)
  • For example, the figure to the right shows a four-note voicing of a C Major triad, which has three chord factors. (wikipedia.org)
  • Degree (music) Sixth chord Triad (music) O'Toole, Patricia (2003). (wikipedia.org)
  • When the third is the bass note, or lowest note, of the expressed triad, the chord is in first inversion. (wikipedia.org)
  • Injury can also occur if the spinal canal protecting the spinal cord has become too narrow ( spinal stenosis ). (medlineplus.gov)
  • Other risk factors include exposure to secondhand smoke, excessive alcohol consumption, and a weakened immune system. (fitfreshlife.com)
  • Vocal cord cancer is often associated with smoking and exposure to certain risk factors, making it crucial to adopt a healthy lifestyle and avoid harmful substances. (fitfreshlife.com)
  • Other risk factors for CP include low birthweight and prematurity. (brainandspinalcord.org)
  • These guidelines focus on stroke risk factors unique to or more common in women, as well as stroke prevention in women. (apta.org)
  • ABSTRACT In view of the widespread use of pesticides in Egypt and the increasing incidence of leukaemia and lymphoma we aimed to assess pesticide exposure and other selected variables as risk factors for lymphoproliferative disorders (leukaemia and non-Hodgkin lymphoma). (who.int)
  • Family history of cancer, exposure to X-rays, smoking and use of hair dyes were not risk factors for lymphoproliferative disorders in univariate analysis. (who.int)
  • Medical risk factors 225-241 c. (cdc.gov)
  • Other risk factors Tobacco 242-245 Alcohol 246-249 Weight gain during pregnancy 250-252 d. (cdc.gov)
  • P = .04) were independent risk factors for OS. (bvsalud.org)
  • Spinal Cord Stimulation Increases Chemoefficacy and Prevents Paclitaxel-Induced Pain via CX3CL1. (iasp-pain.org)
  • Despite increasing utilization of spinal cord stimulation (SCS), its effects on chemoefficacy, cancer progression, and chemotherapy-induced peripheral neuropathy (CIPN) pain remain unclear. (iasp-pain.org)
  • Although the action of spinal cord stimulation (SCS) is ascribed to the direct inhibition of pain transmission in the dorsal horn, these theories do not fully explain the mechanisms by which SCS reduces pain. (medscape.com)
  • The researchers evaluated the outcomes of malpractice cases involving incidental durotomy, and factors associated with which way the case was decided. (sciencedaily.com)
  • The ability to control your arms or legs after a spinal cord injury depends on two factors. (mayoclinic.org)
  • The severity of the symptoms depends on whether the entire cord is injured (complete) or only partially injured (incomplete). (medlineplus.gov)
  • The treatment of vocal cord cancer depends on various factors, such as the stage of the cancer, the patient's overall health, and their preferences. (fitfreshlife.com)
  • Running power outside depends on a few factors starting from what you need power for, or rather the duration of use. (theelectricconnection.com)
  • The chord factor that is in the bass determines the inversion of the chord. (wikipedia.org)
  • For example, if the third is in the bass it is a first inversion chord (figured bass: 6 3) while if the seventh is in the bass the chord is in third inversion (4 2). (wikipedia.org)
  • The illustration shows one possible four-note voicing of a G7 third-inversion chord (written G7/F in lead-sheet chord-symbol notation), with every chord factor being represented once by a voice in the voicing. (wikipedia.org)
  • When spinal cord injuries are in the neck area, symptoms can affect the arms, legs, and middle of the body. (medlineplus.gov)
  • It is important to recognize the signs and symptoms of vocal cord cancer and seek early evaluation to improve the chances of successful treatment. (fitfreshlife.com)
  • Recognizing the symptoms of vocal cord cancer is key to early detection and treatment. (fitfreshlife.com)
  • It is crucial to recognize the symptoms of vocal cord cancer and seek evaluation promptly. (fitfreshlife.com)
  • By educating ourselves about vocal cord cancer and its symptoms, we can increase awareness and promote early intervention, ultimately improving the prognosis for individuals affected by this disease. (fitfreshlife.com)
  • What are the symptoms of Factor II deficiency? (healthline.com)
  • It also can include damage to nerves at the end of the spinal cord, known as the cauda equina. (mayoclinic.org)
  • Many spinal cord injuries and cauda equina syndrome cases are medical emergencies and need surgery right away. (medlineplus.gov)
  • Spine injuries can damage the spinal cord if they are at the upper portion of the lumbar spine or the lumbar and sacral nerve roots (cauda equina) if they are at the lower lumbar spine. (medlineplus.gov)
  • The authors state, "The incidence of confirmed Chagas disease among mothers who donated their neonate's cord blood varied over time," "The incidence of Chagas disease varied over time," and "A strength of this study is its large sample size, particularly because the incidence of this disease is low. (cdc.gov)
  • Conditions such as rheumatoid arthritis , infection, cancer, or osteoporosis can weaken the spine, which normally protects the spinal cord. (medlineplus.gov)
  • The spinal cord sends and receives signals between the brain and the rest of the body. (mayoclinic.org)
  • Pain or an intense stinging sensation caused by damage to the nerve fibers in the spinal cord. (mayoclinic.org)
  • The spinal cord contains nerve fibers and cells. (medlineplus.gov)
  • This type of cancer develops when abnormal cells in the vocal cords multiply and form tumors. (fitfreshlife.com)
  • Vocal cord cancer typically starts with the development of abnormal cells in the vocal cords. (fitfreshlife.com)
  • A chord contains exactly as many factors as it contains unique pitch names (octaves don't matter), while a voicing can have any number of voices that draw from and represent some or all the factors of a chord in various octaves. (wikipedia.org)
  • Thus, a chord with three unique pitch names always has three factors, even if some of those pitches are doubled or omitted in a particular voicing. (wikipedia.org)
  • The "root" chord factor (pitch name "C"), is represented twice in the voicing by voices 1 and 4 in different octaves. (wikipedia.org)
  • The chord factor called the "fifth" (pitch name "G") is represented in voice 2 (shown in red). (wikipedia.org)
  • In music, the third factor of a chord is the note or pitch two scale degrees above the root or tonal center. (wikipedia.org)
  • Vocal cord cancer is a serious medical condition that affects the vocal cords, which are essential for speech and communication. (fitfreshlife.com)
  • Hill, M 2023, ' Cardiopulmonary Health in Middle-aged People with Long-term Cervical and Upper Thoracic Spinal Cord Injuries ', Doctor, Department of Health Sciences, Lund. (lu.se)
  • See also the articles Spinal Cord Injury: Definition, Epidemiology, Pathophysiology in the Physical Medicine and Rehabilitation section of this site, and Spinal Cord Injuries in the Emergency Medicine section. (medscape.com)
  • It can hold a 100-foot length of cord and stores and protects the ends of cords when not in use, the company says. (achrnews.com)
  • [ 3 ] Now called the Paralympics, these games occur every 4 years for persons who fall within 1 of 6 disability groups, including spinal cord injury (SCI). (medscape.com)
  • Factor II deficiency is a very rare blood clotting disorder. (healthline.com)
  • Hemophilia A is an X-linked, recessive disorder caused by deficiency of functional plasma clotting factor VIII (FVIII), which may be inherited or arise from spontaneous mutation. (medscape.com)
  • Testing for inhibitors is indicated when bleeding is not controlled after infusion of adequate amounts of factor concentrate during a bleeding episode. (medscape.com)
  • HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop. (iasp-pain.org)
  • In the meantime, treatments and rehabilitation allow many people with spinal cord injuries to lead productive, independent lives. (mayoclinic.org)
  • Like PT, this measures levels of factors VIII, IX, XI, XII, and von Willebrand factors based on how quickly your blood clots. (healthline.com)
  • Traumatic spinal cord injury (SCI) means there is damage to spinal cord or nerves that run through the backbone (spine). (aapmr.org)
  • Chromatin immunoprecipitation revealed that EBNA2 and the host transcription factors EBF1 and RBPJ were delayed in their recruitment to all viral latency promoters tested, whereas these same factors were recruited efficiently to several host genes, which exhibited increased EBNA2 recruitment. (plos.org)
  • We conclude that EBNA-LP does not simply co-operate with EBNA2 in activating gene transcription, but rather facilitates the recruitment of several transcription factors to the viral genome, to enable transcription of virus latency genes. (plos.org)
  • Normally they are located on the endoplasmic reticulum (ER) membranes and proteolytically activated through RIP (regulated intramembrane proteolysis) on Golgi apparatus to liberate the N-terminus to serve as transcription factors. (medsci.org)
  • The cAMP responsive element (CRE) binding protein 3 (CREB3) family belongs to the bZIP transcription factors. (medsci.org)
  • In the absence of ER stress, these transcription factors are localized in ER membranes. (medsci.org)
  • Then the released N-terminal domains translocate to the nuclei and serve as transcription factors to bind to the CRE sequence to regulate the transcription of target genes, thus functioning in diverse physiological and pathological conditions. (medsci.org)
  • In this section, we will explore the diagnostic procedures for vocal cord cancer and the treatment options that can help manage this condition effectively. (fitfreshlife.com)
  • Before you know how to effectively store your extension cords to prevent safety risks, below are safety tips you should consider while using an extension cord. (theelectricconnection.com)
  • Examines changes to the cardiovascular and coagulation system caused by acute spinal cord injury (SCI) and provides recommendations for preventative measures. (apta.org)
  • The paper determines that while taxation has been a factor in Ireland's successful attraction of investment it cannot be attributed to this factor alone. (lu.se)
  • Vocal cord cancer is more prevalent in individuals who smoke or use tobacco products. (fitfreshlife.com)
  • The spinal cord is located in the spinal canal of your spine in your neck, chest, and back down to the first lumbar vertebra. (medlineplus.gov)
  • Background: Cumulative spine loading has been a suspected risk factor for low back pain for many years, yet the measures that characterize risk have not been well delineated. (cdc.gov)
  • Many scientists are optimistic that advances in research will someday make repair of spinal cord injuries possible. (mayoclinic.org)
  • When it comes to treating vocal cord cancer, early detection and diagnosis play a vital role. (fitfreshlife.com)
  • Diagnosis of factor II deficiency is based on your medical history, any family history of bleeding problems, and lab tests. (healthline.com)
  • It may result from direct injury to the cord itself or indirectly from disease of the nearby bones, tissues, or blood vessels. (medlineplus.gov)
  • It's one of about 13 clotting factors involved in the proper formation of blood clots. (healthline.com)
  • What role does Factor II play in normal blood clotting? (healthline.com)
  • To understand factor II deficiency, it helps to understand the role of factor II (prothrombin) and its activated version, factor IIa (thrombin), in normal blood clotting. (healthline.com)
  • They signal the blood platelets and clotting factors circulating in your bloodstream to come to the wound site. (healthline.com)
  • Once the platelets form a temporary plug, blood-clotting factor II (prothrombin) changes to its activated version, factor IIa (thrombin). (healthline.com)
  • These measure the levels of factor II in your blood. (healthline.com)
  • PT measures the levels of factors I, II, V, VII, and X based on how quickly your blood clots. (healthline.com)
  • The authors incorrectly described the testing performed for the cord blood samples. (cdc.gov)
  • Reviewing the ARC NTL testing results for the Carolinas Cord Blood Bank facility codes, we found that 34 unique samples tested repeat reactive from October 9, 2007, through October 13, 2014. (cdc.gov)
  • results: Geometric mean cord blood MeHg was 0.94 g/L (95% CI: 0.84, 1.07). (cdc.gov)
  • Optimizing selection of double cord blood units for transplantation of adult patients with malignant diseases. (bvsalud.org)
  • Double-unit unrelated cord blood transplantation (DUCBT) is an option in patients for whom a single unit is not sufficient to provide an adequate number of cells . (bvsalud.org)
  • A spinal cord injury involves damage to any part of the spinal cord. (mayoclinic.org)
  • Identifying vocal cord cancer involves several diagnostic procedures. (fitfreshlife.com)
  • Trouble swallowing, unexplained weight loss, trouble breathing, a sensation of something stuck in the throat, and lumps in the neck are also potential signs of vocal cord cancer. (fitfreshlife.com)
  • Factor II deficiency may be inherited. (healthline.com)
  • Hereditary factor II deficiency is extremely rare. (healthline.com)
  • There are currently only 26 documented cases of inherited factor II deficiency in the world. (healthline.com)
  • How is Factor II deficiency diagnosed? (healthline.com)
  • Treatment of factor II deficiency focuses on controlling bleeds, treating underlying conditions, and taking preventive steps before surgeries or invasive dental procedures. (healthline.com)
  • Detection of tissue factor in platelets: why is it so troublesome? (uit.no)
  • A central issue in the adoption of these processes is the transfer of knowledge to the practitioners in the field, whether academic or community, and to recognize the multiple factors that influence adoption and implementation of these processes in all settings and stages (13). (cdc.gov)
  • Treatment for bleeding episodes may include infusions of prothrombin complex, a mixture of factor II (prothrombin) and other clotting factors, to boost your clotting ability. (healthline.com)
  • These factors include the dose (how much), the duration (how long), and how you come in contact with it. (cdc.gov)
  • 4. Binding of EBNA2 and various cellular factors to these genes is delayed. (plos.org)
  • CREB3 (also referred to as LZIP or Luman) was first identified as an interacting protein associated with herpes simplex virus VP16 associated host cellular factor (HCF) by a yeast two hybrid system, it expresses and functions in various adult and fetal tissues [ 4 ]. (medsci.org)
  • Durotomy in Malpractice Cases -- What Factors Affect the Verdict? (sciencedaily.com)
  • Cordpro® is a flexible, yellow, doughnut-shaped reel that divides, stores, and dispenses extension cords and hoses without the use of springs, ratchets, or motorized mechanisms. (achrnews.com)
  • As the user pulls an extension cord from the reel, Cordpro rotates, dispensing only the amount of extension cord needed, leaving the rest inside the reel. (achrnews.com)
  • It may seem ridiculous to give safety reminders on how to store extension cords but lots of hazards have occurred because of the lack of extension cord storage. (theelectricconnection.com)
  • Think about it for a minute, do you own an extension cord? (theelectricconnection.com)
  • Do you want to learn storage tips for extension cords? (theelectricconnection.com)
  • Are you willing to learn safety tips for extension cords? (theelectricconnection.com)
  • We hope the answers in this article help you to stop underrating the importance of safety measures for your extension cord. (theelectricconnection.com)
  • Avoid wet surfaces: Never use wet hands to handle an extension cord or plug in one on wet surfaces. (theelectricconnection.com)
  • You should also be wary of plugging in a wet extension cord to avoid electric shocks. (theelectricconnection.com)
  • Pull the plug: While unplugging your extension cord, do not pull the cord rather pull the plug connected to the cord. (theelectricconnection.com)
  • Avoid use on foot traffic areas: people can easily trip on extension cords so it is advisable not to be used on where there is a lot of foot traffic. (theelectricconnection.com)
  • Use good extension cord: You may be tempted to use damaged, frayed extension cords but don't. (theelectricconnection.com)
  • Below are some simple extension cord storage ideas you can try out in minutes with little or no cost. (theelectricconnection.com)
  • This is the method of looping your extension cords and then hanging them on a hook in your storage closet or garage. (theelectricconnection.com)
  • Also, ensure you use a sturdy hook so it can support the weight of your extension cords. (theelectricconnection.com)
  • All you have to do is spool your extension cords around it in the same direction and you are good to go.Ensure it is not too tight or loose so it is not damaged or loose. (theelectricconnection.com)
  • All you have to do is hang the extension cords like you would hand a tie or belt on the hanger and you are good to go. (theelectricconnection.com)
  • Did you find the safety and storage tips useful in helping you keep your extension cords safe and accessible? (theelectricconnection.com)
  • You can reach out to us at The Electric Connection for inquiries and questions concerning extension cords or any other electric concerns. (theelectricconnection.com)
  • Can I use an extension cord to run power outside? (theelectricconnection.com)
  • Yes, you can use an extension cord to run power outside if you only need power for a short time. (theelectricconnection.com)
  • An extension cord built for outdoor use has you covered from hours to up to two days outside. (theelectricconnection.com)
  • Purchase an extension cord identified as an outdoor extension cord. (theelectricconnection.com)
  • Also, note that even outdoor extension cords built for use outside should not exceed more than a day or two in use. (theelectricconnection.com)
  • After ensuring you use an outdoor extension cord, verify the wattage before purchasing it. (theelectricconnection.com)
  • During this procedure, a small piece of tissue is removed from the vocal cord and examined under a microscope for any signs of cancer. (fitfreshlife.com)
  • Metastatic epidural spinal cord compression (MESCC) is an oncologic emergency that is most often treated with radiotherapy (RT) alone [ 1 , 2 ]. (springer.com)
  • Early evaluation is crucial in identifying vocal cord cancer and initiating appropriate treatment. (fitfreshlife.com)
  • People who have had a spinal cord injury also may experience mental, emotional and social side effects. (mayoclinic.org)
  • The third in both major and augmented chords is major (E♮ in C) and the third in both minor and diminished chords is minor (E♭ in C). In music and music theory, a tenth is the note ten scale degrees from the root of a chord and also the interval between the root and the tenth. (wikipedia.org)
  • In Tertian harmony, chords are made more complex, or "extended", by introducing additional chord factors stacked in thirds. (wikipedia.org)
  • An additional factor for the rapid growth of participation in sporting activities by those with paraplegia is the improvement in accessibility, as well as the improved designs of sporting facilities and wheelchairs, which allow for meaningful athletic competition. (medscape.com)
  • It is vital to detect vocal cord cancer in its early stages to improve the chances of successful treatment. (fitfreshlife.com)
  • The lowest part of the spinal cord not damaged after an injury is known as the neurological level of the injury. (mayoclinic.org)