Substances used to allow enhanced visualization of tissues.
Triiodo-substituted derivatives of BENZOIC ACID.
An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
A non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures.
A low-osmolar, ionic contrast medium used in various radiographic procedures.
A commonly used x-ray contrast medium. As DIATRIZOATE MEGLUMINE and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
A versatile contrast medium used for DIAGNOSTIC X-RAY RADIOLOGY.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Inorganic compounds that contain iodine as an integral part of the molecule.
A radiopaque medium used for urography, angiography, venography, and myelography. It is highly viscous and binds to plasma proteins.
The escape of diagnostic or therapeutic material from the vessel into which it is introduced into the surrounding tissue or body cavity.
Radiography of any part of the urinary tract.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Gadolinium. An element of the rare earth family of metals. It has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
Radiography of the uterus and fallopian tubes after the injection of a contrast medium.
A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
A preparation of oil that contains covalently bound IODINE. It is commonly used as a RADIOCONTRAST AGENT and as a suspension medium for CHEMOTHERAPEUTIC AGENTS.
Radiography of blood vessels after injection of a contrast medium.
The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.
Radiography of the heart and great vessels after injection of a contrast medium.
Iodinated pyridine derivatives that are often used as contrast media.
A contrast medium in diagnostic radiology with properties similar to those of diatrizoic acid. It is used primarily as its sodium and meglumine (IOTHALAMATE MEGLUMINE) salts.
Methods for assessing the patency of the fallopian tubes.
Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
Pathological processes of the KIDNEY or its component tissues.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.
Benzoic acid esters or salts substituted with one or more iodine atoms.
Delivery of drugs into an artery.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Thorium oxide (ThO2). A radiographic contrast agent that was used in the early 1930s through about 1954. High rates of mortality have been linked to its use and it has been shown to cause liver cancer.
Injections made into a vein for therapeutic or experimental purposes.
A chronic, acquired, idiopathic, progressive eruption of the skin that occurs in the context of RENAL FAILURE. It is sometimes accompanied by systemic fibrosis. The pathogenesis seems to be multifactorial, with postulated involvement of circulating fibrocytes. There is a strong association between this disorder and the use of gadolinium-based contrast agents.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Instruments or technological means of communication that reach large numbers of people with a common message: press, radio, television, etc.
An inert iodine-containing agent which is opaque to X-RAYS. It is used mainly for BRAIN and SPINAL CORD visualization.
Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
Radiography of the vascular system of the brain after injection of a contrast medium.
A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
Inorganic compounds that contain tungsten as an integral part of the molecule.
Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.
Medical and skilled nursing services provided to patients who are not in an acute phase of an illness but who require a level of care higher than that provided in a long-term care setting. (JCAHO, Lexikon, 1994)
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.
The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.
Culture media containing biologically active components obtained from previously cultured cells or tissues that have released into the media substances affecting certain cell functions (e.g., growth, lysis).
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
X-ray visualization of the spinal cord following injection of contrast medium into the spinal arachnoid space.
Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.
The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
Elements of limited time intervals, contributing to particular results or situations.
Radiography of the gallbladder after ingestion of a contrast medium.
A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Production of an image when x-rays strike a fluorescent screen.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
An imaging test of the BILIARY TRACT in which a contrast dye (RADIOPAQUE MEDIA) is injected into the BILE DUCT and x-ray pictures are taken.
An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Space between the dura mater and the walls of the vertebral canal.
The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
Used in copolymerization reactions, in the Diels-Alder(diene)synthesis, in the preparation of resins, pharmaceuticals and agricultural chemicals. It is a powerful irritant and causes burns.
Radiographic study of the lymphatic system following injection of dye or contrast medium.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS.
An INTERVERTEBRAL DISC in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Economic aspects related to the management and operation of a hospital.
A vascular anomaly that is a collection of tortuous BLOOD VESSELS and connective tissue. This tumor-like mass with the large vascular space is filled with blood and usually appears as a strawberry-like lesion in the subcutaneous areas of the face, extremities, or other regions of the body including the central nervous system.
Motion pictures of the passage of contrast medium through blood vessels.
Small encapsulated gas bubbles (diameters of micrometers) that can be used as CONTRAST MEDIA, and in other diagnostic and therapeutic applications. Upon exposure to sufficiently intense ultrasound, microbubbles will cavitate, rupture, disappear, release gas content. Such characteristics of the microbubbles can be used to enhance diagnostic tests, dissolve blood clots, and deliver drugs or genes for therapy.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)
A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.
Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)
A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
Sulfur hexafluoride. An inert gas used mainly as a test gas in respiratory physiology. Other uses include its injection in vitreoretinal surgery to restore the vitreous chamber and as a tracer in monitoring the dispersion and deposition of air pollutants.
1-Deoxy-1-(methylamino)-D-glucitol. A derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. Often used in conjunction with iodinated organic compounds as contrast medium.
Radiography of the ventricular system of the brain after injection of air or other contrast medium directly into the cerebral ventricles. It is used also for x-ray computed tomography of the cerebral ventricles.
Computer systems or networks designed to provide radiographic interpretive information.
Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight.
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
Radiographic visualization or recording of a vein after the injection of contrast medium.
The presence of chyle in the thoracic cavity. (Dorland, 27th ed)
The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance.
A ubiquitous sodium salt that is commonly used to season food.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.
Introduction of substances into the body using a needle and syringe.
Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
Detection and counting of scintillations produced in a fluorescent material by ionizing radiation.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Platforms that provide the ability and tools to create and publish information accessed via the INTERNET. Generally these platforms have three characteristics with content user generated, high degree of interaction between creator and viewer, and easily integrated with other sites.
Pathological processes consisting of the union of the opposing surfaces of a wound.
A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Congenital vascular anomalies in the brain characterized by direct communication between an artery and a vein without passing through the CAPILLARIES. The locations and size of the shunts determine the symptoms including HEADACHES; SEIZURES; STROKE; INTRACRANIAL HEMORRHAGES; mass effect; and vascular steal effect.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
The combination of hemodialysis and hemofiltration either simultaneously or sequentially. Convective transport (hemofiltration) may be better for removal of larger molecular weight substances and diffusive transport (hemodialysis) for smaller molecular weight solutes.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
CULTURE MEDIA free of serum proteins but including the minimal essential substances required for cell growth. This type of medium avoids the presence of extraneous substances that may affect cell proliferation or unwanted activation of cells.
Roentgenography of a joint, usually after injection of either positive or negative contrast medium.
A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.
Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
Tumors or cancer of the LIVER.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
The means of interchanging or transmitting and receiving information. Historically the media were written: books, journals, newspapers, and other publications; in the modern age the media include, in addition, radio, television, computers, and information networks.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Diminished or absent ability of a female to achieve conception.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.
Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.
Disease having a short and relatively severe course.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.
A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
The veins and arteries of the HEART.
The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
The study of MAGNETIC PHENOMENA.
The circulation of the BLOOD through the vessels of the KIDNEY.
Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
Methods of creating machines and devices.
The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.
Techniques used in studying bacteria.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
The return of a sign, symptom, or disease after a remission.
Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.
Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.
The outer zone of the KIDNEY, beneath the capsule, consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The condition of an anatomical structure's being constricted beyond normal dimensions.
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Regional patterns of myocardial sympathetic denervation in dilated cardiomyopathy: an analysis using carbon-11 hydroxyephedrine and positron emission tomography. (1/6913)

OBJECTIVE: To assess presynaptic function of cardiac autonomic innervation in patients with advanced congestive heart failure using positron emission tomography (PET) and the recently developed radiolabelled catecholamine analogue carbon-11 hydroxyephedrine (HED) as a marker for neuronal catecholamine uptake function. DESIGN AND PATIENTS: 29 patients suffering from dilated cardiomyopathy with moderate to severe heart failure were compared with eight healthy controls. Perfusion scan was followed by HED dynamic PET imaging of cardiac sympathetic innervation. The scintigraphic results were compared with markers of disease severity and the degree of sympathetic dysfunction assessed by means of heart rate variability. RESULTS: In contrast to nearly normal perfusions, mean (SD) HED retention in dilated cardiomyopathy patients was abnormal in 64 (32)% of the left ventricle. Absolute myocardial HED retention was 10.7 (1.0)%/min in controls v 6.2 (1.6)%/min in dilated cardiomyopathy patients (p < 0.001). Moreover, significant regional reduction of HED retention was demonstrated in apical and inferoapical segments. HED retention was significantly correlated with New York Heart Association functional class (r = -0.55, p = 0. 002) and ejection fraction (r = 0.63, p < 0.001), but not, however, with plasma noradrenaline concentrations as well as parameters of heart rate variability. CONCLUSIONS: In this study, using PET in combination with HED in patients with dilated cardiomyopathy, not only global reduction but also regional abnormalities of cardiac sympathetic tracer uptake were demonstrated. The degree of abnormality was positively correlated to markers of severity of heart failure. The pathogenetic mechanisms leading to the regional differences of neuronal damage as well as the prognostic significance of these findings remain to be defined.  (+info)

3D angiography. Clinical interest. First applications in interventional neuroradiology. (2/6913)

3D angiography is a true technical revolution that allows improvement in the quality and safety of diagnostic and endovascular treatment procedures. 3D angiography images are obtained by reconstruction of a rotational angiography acquisition done on a C-arm (GE Medical Systems) spinning at 40 degrees per second. The carotid or vertebral selective injection of a total of 15 ml of non-ionic contrast media at 3 ml/sec over 5 seconds allows the selection of the "arterial phase". Four hundred sixty 3D angiographic studies were performed from December 1996 to September 1998 on 260 patients and have been analyzed in MIP (Maximum Intensity Projection) and SSD (Shaded Surface Display) views. The exploration of intracranial aneurysms is simplified and only requires, for each vascular axis, a biplane PA and Lateral run followed by a single rotational angiography run. The 3D angiography image is available on the workstation's screen (Advantage Workstation 3.1, GE Medical Systems) in less than 10 minutes after the acquisition of the rotational run. It therefore allows one to analyze, during the intervention, the aneurysm's angioarchitecture, in particular the neck, and select the best therapeutic technique. When endovascular treatment is the best indication, 3D angiography allows one to define the optimal angle of view and accurately select the microcoils dimensions. 3D angiography replaces the multiple oblique views that used to be required to analyze the complex aneurysms and therefore allows a reduction of the total contrast medium quantity, the patient X-ray dose and the length of the intervention time which is a safety factor. Also, in particular for complex cases, it brings additional elements complementing the results of standard 2D DSA and rotational angiograms. In the cervical vascular pathology, 3D angiography allows for a better assessment of the stenosis level and of dissection lesions. Our current research activities focus on the matching without stereotactic frame between 3D X-ray angiography and volumetric MR acquisition, which should allow us to improve the treatment of intracerebral arterio-venous malformations (AVMs).  (+info)

3D MRI of the membranous labyrinth. An age related comparison of MR findings in patients with labyrinthine fibrosis and in persons without inner ear symptoms. (3/6913)

PURPOSE: We compared MRI of the membranous labyrinth in patients with chronic non-neoplastic inner ear disease and MR signs of labyrinthine fibrosis and controls depending on their age, in order to establish whether there were any MR differences regarding patient age groups, control age groups and between the patients and controls themselves. MATERIALS AND METHODS: Clinical ENT examinations as well as a T2* weighted 3D CISS (Constructive Interference in Steady State) sequence with a slice thickness of 0.7 mm were performed. Our collective was subdivided as follows: 0-19 years (10 controls, 3 patients with chronic non-neoplastic inner ear disease), 20-49 years (55 controls, 8 patients), 50 years and older (40 controls, 22 patients). Detectability of labyrinthine structures (e.g. cochlea, vestibule, semicircular canals) and filling defects were evaluated. RESULTS: In the 3 age-groups of the control collective no significant differences were observed in the membranous labyrinth. However differences concerning labyrinthine detectability emerged between controls and patients in both the 20-49 years and 50 years and older age groups. In the patient collective the 3 age groups showed no significant discrepancy in the mean number of lesions. CONCLUSION: Filling defects of the membranous labyrinth on 3D CISS MR images are pathological even in older persons. We would therefore recommend high resolution T2* weighted MRI in the case of suspected labyrinthine fibrosis.  (+info)

Angiographical extravasation of contrast medium in hemorrhagic infarction. Case report. (4/6913)

Leakage of the contrast medium was noted on angiograms of a patient whose autopsied brain disclosed typical pathological findings of hemorrhagic infarction. The case was a 63-year old woman with mitral valve failure, who suddenly had loss of consciousness and right-sided hemiplegia. The left carotid angiography performed six hours after onset demonstrated middle cerebral arterial axis occlusion, and the second angiography performed three days after onset displayed recanalization of the initially occluded artery as well as extravasation of the contrast medium. Fourteen days after onset the patient died and an autopsy was performed. The brain demonstrated perivascular punctate hemorrhages in the area supplied by the middle cerebral artery, and neither hematoma nor microaneurysm was disclosed pathologically. A short discussion is given on the possible relationship between recanalization and hemorrhagic infarction. The clinical assessment of hemorrhagic infarction has not been established successfully.  (+info)

Comparative cytotoxicity of ionic and non-ionic radiocontrast agents on MDCK cell monolayers in vitro. (5/6913)

BACKGROUND: Intravascular radiocontrast agents may cause acute renal failure, particularly in patients with pre-existing renal insufficiency. Direct cytotoxic effects of radiocontrast agents on renal tubular cells may contribute to the pathogenesis of radiocontrast-induced nephropathy. METHODS: We analysed the cytotoxicity of the ionic radiocontrast agents diatrizoate (monomeric) and ioxaglate (dimeric), as well as of the non-ionic radiocontrast agents iohexol (monomeric) and iodixanol (dimeric) on the renal epithelial Madin Darby Canine Kidney (MDCK) cell line grown on permeable supports. The toxicity assays assessed cell viability, transmonolayer resistance and inulin permeability between the apical and basal cell culture compartment. In addition, the distribution of the tight-junction-associated membrane proteins ZO-1 and occludin was analysed using immunofluorescence microscopy. RESULTS: In all assays the high osmolal ionic compound diatrizoate had significant cytotoxic effects that included the partial redistribution of the tight-junction-associated membrane proteins into a cytoplasmic compartment. To a lesser extent this redistribution also occurred with the dimeric ionic compound ioxaglate, but not with the non-ionic radiocontrast agents. With regards to cell viability, transmonolayer resistance and inulin permeability the radiocontrast agents with reduced osmolality were significantly less toxic than diatrizoate, independent of their ionic strength. CONCLUSIONS: Physicochemical factors contribute to the cytotoxicity of radiocontrast agents in vitro. The redistribution of tight-junction-associated membrane proteins by the ionic radiocontrast agents corresponds with the loss of the barrier function of the epithelial cell monolayer, which is a major pathophysiological mechanism in acute renal failure. The radiocontrast agents with reduced osmolality are less cytotoxic than diatrizoate, independent of their ionicity. Hyperosmolality appears to be a more important determinant of the cytotoxicity of diatrizoate than ionic strength.  (+info)

Enhancement of endocytosis due to aminophospholipid transport across the plasma membrane of living cells. (6/6913)

Formation of intracellular vesicles is initiated by membrane budding. Here we test the hypothesis that the plasma membrane surface area asymmetry could be a driving force for vesicle formation during endocytosis. The inner layer phospholipid number was therefore increased by adding exogenous aminophospholipids to living cells, which were then translocated from the outer to the inner layer of the membrane by the ubiquitous flippase. Addition of either phosphatidylserine or phosphatidylethanolamine led to an enhancement of endocytosis, showing that the observed acceleration does not depend on the lipid polar head group. Conversely, a closely related aminophospholipid that is not recognized by the flippase, lyso-alpha-phosphatidylserine, inhibited endocytosis, and similar results were obtained with a cholesterol derivative that also remains in the plasma membrane outer layer. Thus an increase of lipid concentration in the inner layer enhanced internalization, whereas an increase of the lipid concentration in the outer layer inhibited internalization. These experiments suggest that transient asymmetries in lipid concentration might contribute to the formation of endocytic vesicles.  (+info)

Thorotrast associated nodular regenerative hyperplasia of the liver. (7/6913)

A case of nodular regenerative hyperplasia (NRH) of the liver is described in association with exposure to the radiographic contrast medium Thorotrast. This is the first case in which the pathological findings have been fully documented. It is suggested that NRH may have developed through Thorotrast induced damage to portal vein radicles.  (+info)

Intravaginal saline as a contrast agent for cervical sonography in the obstetric patient. (8/6913)

OBJECTIVE: To determine whether intravaginal saline alters visualization of the cervix during endovaginal sonographic examinations. DESIGN: A prospective trial with comparison of sonographic measurements of cervical length prior to and after administration of an intravaginal contrast agent. SUBJECTS: Patients with an indication for endovaginal ultrasonographic assessment of the cervix were considered as candidates for the study. METHODS: After assessment of cervical dimensions and contour of the internal cervical os, 10 ml of normal saline was placed intravaginally via a needleless syringe. Pre- and post-contrast sonographic examinations of the cervix were compared. RESULTS: Twenty-six patients were enrolled. No differences were observed in the identification of funnelling (37% in each group, p = 1.0) or the quantification of cervical length for the entire cohort (p = 0.95). However, in a subset of patients in whom the external os was not satisfactorily visualized (23%), intravaginal contrast resulted in a mean difference in cervical length pre- and post-saline infusion of 6.4 mm compared to 1.4 mm in patients in whom the external os could be easily identified (p < 0.001). No patient expressed undue discomfort related to the administration of contrast. CONCLUSION: Intravaginal saline assists in visualization of the cervix during endovaginal sonography for selected patients in whom precise identification of the external os is difficult.  (+info)

TY - JOUR. T1 - A fundamental study for quantitative measurement of ultrasound contrast concentration by low mechanical index contrast ultrasonography. AU - Yamada, Satoshi. AU - Komuro, Kaoru. AU - Taniguchi, Mariko. AU - Uranishi, Ayumi. AU - Komatsu, Hiroshi. AU - Asanuma, Toshihiko. AU - Ishikura, Fuminobu. AU - Onozuka, Hisao. AU - Mikami, Taisei. AU - Tsutsui, Hiroyuki. AU - Beppu, Shintaro. PY - 2006/6. Y1 - 2006/6. N2 - Purpose. In high mechanical index (MI) contrast ultrasonography it has been shown that the power of contrast signal intensity (CI) has a strong linear correlation with the concentration of the ultrasound contrast agent under conditions of constant applied acoustic pressure. However, it is unclear whether the linearity is preserved in low-MI contrast ultrasonography. Thus, we investigated the relationship between ultrasound contrast concentration and CI in vitro. Methods. Solutions of the ultrasound contrast agents Definity and Imagent were prepared at concentrations of ...
PURPOSE:. To investigate the possibility of detecting cardiac transplant rejection and determining its degree of severity with magnetic resonance (MR) imaging with a blood pool contrast agent.. MATERIALS AND METHODS:. Rat allogeneic (PVG to Wistar/Kyoto, n = 9) and syngeneic (Wistar/Kyoto to Wistar/Kyoto, n = 6) heterotopic heart transplantations were performed. On the 2nd and 6th postoperative days, an ultrasmall superparamagnetic iron oxide, or USPIO, contrast agent was injected intravenously at a dose of 2 mg of iron per kilogram of body weight. The injection was followed by three-dimensional T1-weighted MR imaging of the heart grafts with an imaging time of approximately 2 minutes for each image for 44 minutes. The signal intensity (SI) was measured in the myocardium over time, and the relative enhancement was calculated. After the 6th day, the rats were sacrificed, and the morphology of the transplanted hearts was assessed histologically. The CIs for the difference of the means on day 2 and ...
TY - JOUR. T1 - Liver perfusion changes occurring during pancreatic islet engraftment. T2 - A dynamic contrast-enhanced magnetic resonance study. AU - Esposito, A.. AU - Palmisano, A.. AU - Maffi, P.. AU - Malosio, M. L.. AU - Nano, R.. AU - Canu, T.. AU - De Cobelli, F.. AU - Piemonti, L.. AU - Ironi, G.. AU - Secchi, A.. AU - Del Maschio, A.. PY - 2014/1. Y1 - 2014/1. N2 - The aim of this study was to investigate liver microvascular adaptation following the intraportal infusion of pancreatic islets (pancreatic islet transplantation [islet-tx]) in diabetic patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). DCE-MRI was performed before and 7 days after islet-tx in six diabetic patients. Initial area under curve (AUC60) and volume transfer coefficient (Ktrans) were assessed as markers of liver perfusion. Clinical and metabolic monthly follow-up was performed in all patients, considering fasting C-peptide and β-score as main indices of graft function. High variability ...
TY - JOUR. T1 - Antiangiogenic therapy for primary liver cancer. T2 - Correlation of changes in dynamic contrast-enhanced magnetic resonance imaging with tissue hypoxia markers and clinical response. AU - Yopp, Adam C.. AU - Schwartz, Lawrence H.. AU - Kemeny, Nancy. AU - Gultekin, David H.. AU - Gönen, Mithat. AU - Bamboat, Zubin. AU - Shia, Jinru. AU - Haviland, Dana. AU - DAngelica, Michael I.. AU - Fong, Yuman. AU - Dematteo, Ronald P.. AU - Allen, Peter J.. AU - Jarnagin, William R.. PY - 2011/8/1. Y1 - 2011/8/1. N2 - Background: This study utilized the imaging data of primary liver cancer (PLC) treated with floxuridine (FUDR) and bevacizumab to test the hypothesis that dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters correlate with tissue hypoxia markers and treatment outcome. Methods: Seventeen patients with PLC were treated with hepatic artery infusional (HAI) FUDR for 14 days followed by systemic bevacizumab therapy. DCE-MRI images were obtained at baseline ...
Some patients will experience stinging or burning, but other patients will have little to no immediate discomfort. Clinical risk associated with contrast angiography in metformin treated patients: a clinical review. The Iodinated Contrast Media Guideline is intended to assist RANZCR, its staff, Fellows, members and other individuals involved in the administration of iodinated contrast media to patients undergoing medical imaging procedures. The aim of the Part 1 of Safe Use of Iodine-containing Contrast Media guidelines is to critically review the present recent evidence with the above trend in mind, and try to formulate new practical guidelines for all hospital physicians to provide the safe use of contrast media in diagnostic and interventional studies. These revised guidelines are necessary because of the ever-changing literature about both iodinated contrast media and gadolinium-based contrast agents (GBCAs). Metformin and contrast media: where is the conflict? Henrik S. Thomsen. All those ...
RISKS OF GADOLINIUM-BASED MRI INTRAVENOUS CONTRAST AGENTS answers are found in the Guide to Diagnostic Tests powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
This study intends to assess the ability of contrast-enhanced ultrasound in the detection of benign and malignant ovarian masses compared to unenhanced ultrasound.. By using an intravascular contrast agent, this noninvasive and feasible imaging technique will allow the investigators to define specific microcirculation patterns in 100 women with ovarian lesions.. The intravascular contrast agent properties will be compared between benign and malignant adnexal masses.. The final purpose of this ultrasonography is to allow the early detection of tumors and to improve the characterization between benign and malignant lesions. ...
TY - JOUR. T1 - Reactions to intravenous contrast media. T2 - Part I: Severe and fatal cardiovascular reactions in a canine dehydration model. AU - Katzberg, Richard W. AU - Morris, T. W.. AU - Schulman, G.. AU - Faillace, R. T.. AU - Boylan, L. M.. AU - Foley, M. J.. AU - Spataro, R. F.. AU - Fischer, H. W.. PY - 1983. Y1 - 1983. N2 - Investigations into the nature of severe and fatal reactions to contrast media have been severely limited by their unpredictable occurrence in the clinical setting and the absence of suitable laboratory models. The authors report their experience with a canine dehydration model. Intravenous administration of 2 ml/kg of 76% sodium methylglucamine diatrizoate resulted in vomiting, shock, inappropriate slowing of the heart rate, and death. ECG findings indicated suppression of sinoatrial node automaticity, a decrease in the rate of atrioventricular conduction, and depression of myocardial contractility. These results suggest two possible mechanisms: (a) enhanced ...
RISKS OF IODINATED CT INTRAVENOUS CONTRAST AGENTS answers are found in the Guide to Diagnostic Tests powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Differential MR delayed enhancement patterns of chronic myocardial infarction between extracellular and intravascular contrast media
TY - GEN. T1 - Segmentation and classification of breast tumor using dynamic contrast-enhanced MR images. AU - Zheng, Yuanjie. AU - Baloch, Sajjad. AU - Englander, Sarah. AU - Schnall, Mitchell D.. AU - Shen, Dinggang. PY - 2007/12/1. Y1 - 2007/12/1. N2 - Accuracy of automatic cancer diagnosis is largely determined by two factors, namely, the precision of tumor segmentation, and the suitability of extracted features for discrimination between malignancy and benignancy. In this paper, we propose a new framework for accurate characterization of tumors in contrast enhanced MR images. First, a new graph cut based segmentation algorithm is developed for refining coarse manual segmentation, which allows precise identification of tumor regions. Second, by considering serial contrast-enhanced images as a single spatio-temporal image, a spatio-temporal model of segmented tumor is constructed to extract Spatio-Temporal Enhancement Patterns (STEPs). STEPs are designed to capture not only dynamic ...
TY - JOUR. T1 - Quantitative parameters in dynamic contrast-enhanced magnetic resonance imaging for the detection and characterization of prostate cancer. AU - Wei, Cheng. AU - Jin, Bowen. AU - Szewczyk-Bieda, Magdalena. AU - Gandy, Stephen. AU - Lang, Stephen. AU - Zhang, Yilong. AU - Huang, Zhihong. AU - Nabi, Ghulam. PY - 2018/3/23. Y1 - 2018/3/23. N2 - Objectives: to assess the diagnostic accuracy of quantitative parameters of DCE-MRI in multi-parametric MRI (mpMRI) in comparison to the histopathology (including Gleason grade) of prostate cancer.Patients and methods: 150 men with suspected prostate cancer (abnormal digital rectum examination and or elevated prostate-specific antigen) received pre-biopsy 3T mpMRI and were recruited into peer-reviewed, protocol-based prospective study. The DCE-MRI quantitative parameters (Ktrans (influx transfer constant) and kep (efflux rate constant)) of the cancerous and normal areas were recorded using four different kinetic models employing Olea Sphere ...
Summary:Intravenous contrast media, specifically the gadolinium chelates, are well accepted for use in the clinical practice of magnetic resonance imaging. The gadolinium chelates are considered to be very safe and lack (in intravenous use) the nephrotoxicity found with iodinated contrast media. Min
North America, Europe, Asia-Pacific, and Rest of the World (RoW) are the regions considered for a geographic analysis of the global contrast media/contrast agents market. North American contrast media/contrast agents market is expected to account for the largest share of the global contrast media/contrast agents market. However, the Asia Pacific contrast media/contrast agents market is expected to grow at the highest CAGR in the forecast period. This growth can be attributed to the increasing R&D investments and favorable demographic scenario in China, rising aging population and cancer incidence in Japan, growing investments in the Indian radiology market, and growing focus of market players & increasing government support in other APAC countries.. The prominent players in the global contrast media/contrast agents market include GE Healthcare (US), Bracco Imaging S.p.A. (Bracco) (Italy), Bayer HealthCare (Bayer) (Germany), and Guerbet Group (Guerbet) (France).. Don t miss out on business ...
The clinical pattern of diagnostic radiology has been made possible by progresss by diagnostic equipment and fact-finding techniques, as in the contrast media that permit visual image of the inside informations in the internal construction or variety meats that would non otherwise be incontrovertible. Contrast media can be categorized as drug because the can absorb into the systemic circulation and may impact a physiologic response.. When an anatomical country is filled or outlined by contrast media. The image appears to be white ( positive contrast ) but if it is a negative contrast it makes the organ appear darker. Contrast media are solution or either gasses introduced it to the organic structure to supply contrast between an anatomical organ and its environing tissues.. To increase the visibleness of the construction, Ba sulphate is used as a substance. The pick of contrast media is ever been debate affair but it is ever the duty of the radiotherapist to do a rational determination on choice ...
Antivascular treatments can either be antiangiogenic or targeting established tumour vasculature. These treatments affect the tumour microvasculature and microenvironment but may not change clinical measures like tumour volume and growth. In research on antivascular treatments, information on the tumour vasculature is therefore essential. Preclinical research is often used for optimization of antivascular drugs alone or in combined treatments. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an in vivo imaging method providing vascular information, which has become an important tool in both preclinical and clinical research. This review discusses common DCE-MRI imaging protocols and analysis methods and provides an overview of preclinical research on antivascular treatments utilizing DCE-MRI.
Currently there are no approved biomarkers for the pre-symptomatic diagnosis of Alzheimers disease (AD). Cathepsin-D (Cat-D) is a lysosomal protease that is present at elevated levels in amyloid plaques and neurons in patients with AD and is also elevated in some cancers. We have developed a magnetic resonance imaging (MRI)/fluorescent contrast agent to detect Cat-D enzymatic activity. The purpose of this study was to investigate the cellular and tissue uptake of this MRI/fluorescent contrast agent. The agent consists of an MRI probe [DOTA-caged metal ion (Gd3+ or Tm3+)] and a fluorescent probe coupled to a cell-penetrating-peptide sequence by a Cat-D recognition site. The relaxivity of Gd3+-DOTA-CAT(cleaved) was measured in 10% heat-treated bovine serum albumin (BSA) phantoms to assess contrast efficacy at magnetic fields ranging from 0.24 mT to 9.4 T. In vitro, Tm3+-DOTA-CAT was added to neuronal SN56 cells over-expressing Cat-D and live-cell confocal microscropy was performed at 30 min. ...
Heterogeneity is a common finding within tumours. We evaluated the imaging features of tumours based on the decomposition of tumoural dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data to identify their prognostic value for breast cancer survival and to explore their biological importance. Imaging features (n = 14), such as texture, histogram distribution and morphological features, were extracted to determine their associations with recurrence-free survival (RFS) in patients in the training cohort (n = 61) from The Cancer Imaging Archive (TCIA). The prognostic value of the features was evaluated in an independent dataset of 173 patients (i.e. the reproducibility cohort) from the TCIA I-SPY 1 TRIAL dataset. Radiogenomic analysis was performed in an additional cohort, the radiogenomic cohort (n = 87), using DCE-MRI from TCGA-BRCA and corresponding gene expression data from The Cancer Genome Atlas (TCGA). The MRI tumour area was decomposed by convex analysis of mixtures (CAM), resulting
TY - JOUR. T1 - Glomerular filtration rate estimated after multiple injections of contrast medium during angiography. AU - Boijsen, M.. AU - Granerus, G.. AU - Jacobsson, L.. AU - Björneld, L.. AU - Aurell, M.. AU - Tylen, Ulf. PY - 1988. Y1 - 1988. N2 - In twenty-six patients referred for angiography, clearance of contrast medium was determined with x-ray fluorescence analysis after multiple injections of contrast medium. A formula for correction of the injected amount, which takes into consideration the different times of contrast medium injections, approximating the total injected amount into one injection, was used. A single injection clearance of 51Cr-EDTA was determined at the same time. the results showed a good correlation between the clearance of contrast medium after multiple injections and the 51Cr-EDTA clearance after a single injection (r=0.945). the correlation between contrast medium clearance calculated without correction for the different injection times, and 51Cr-EDTA ...
Abstract: Significant progress has been made in recent years in the development of effective ultrasonic contrast agents for inducing better image contrast of certain anatomic structures in the body for diagnostic purposes. An ideal ultrasonic contrast agent should have the following characteristics: (1) be nontoxic, (2) be capable of producing sufficient contrast via intravenous injection, and (3) have a long persistence time. Gaseous contrast agents such as Albunex[sup (registered)] (Molecular Biosystems), Echovist[sup (registered)] and Levovist[sup (registered)] (Schering), and EchoGen[sup (registered)] (Sonus) have been shown to satisfy a majority of these requirements. Albunex[sup (registered)] was approved in 1994 by the FDA for clinical use. The most intriguing application of these contrast agents is in harmonic pulse-echo and Doppler imaging since nonlinear resonance of microairbubbles would yield echoes at the harmonics of the incident frequency. If detection is made at one of these ...
Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Biomarker for the Pharmacological Response of PTK787/ZK 222584, an Inhibitor of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, in Patients With Advanced Colorectal Cancer and Liver Metastases: Results From Two Phase I ...
Optimized Fast Dynamic Contrast-Enhanced Magnetic Resonance Imaging of the Prostate Effect of Sampling Duration on Pharmacokinetic ...
Acute adverse reactions to contrast media will occur at a certain rate. Non-ionic iodinated contrast is said to have an adverse reaction rate of about 0.6 to 3.1% [6-10]. This rate is said to be about 0.07 to 0.67% for gadolinium contrast media [6-9].. The ACR Manual on Contrast Media [1] and EUSR Guidelines on Contrast Media [2] recommend premedication for patients at risk for adverse reactions to contrast, but the definition of at-risk has some variation among protocols and studies. The ACR Manual states patients with a history of adverse reactions should be premedicated, but does not elaborate on the degree of the reaction. The ESUR Guidelines, on the other hand, includes patients with a history of moderate or severe reactions. When following the ESUR Guidelines, patients with history of mild reactions to contrast undergo contrast enhanced examinations without premedication. (We chose to follow and reference the older versions of the ACR Manual and ESUR Guidelines, as these were the ones ...
The Global Contrast Media Market is going to continue with the same trends of growth during the forecast period. The major factors influencing the growth of the market include increasing technology advancement in contrast medium, increasing prevalence of cancer and cardiac diseases, growth in emerging markets for imaging technology, increasing demand for diagnostics, and image guide procedures and various others. Whereas, the risk of side effects and adverse effects of the contrast media may hamper the growth of the market. Exclusive Sample Copy @https://www.marketresearchfuture.com/sample_request/1284 .. Contrast media are substances which are utilized to improve the contrast of fluids in the body during medical imaging. It is basically used to enhance the visibility of blood vessels and GI tract. The global contrast media market is growing with the steady pace; mainly due to the increasing prevalence of different diseases such as GIT diseases and cardiac diseases. According to a recent study ...
Dynamic contrast-enhanced (DCE)-MRI is useful to assess the early effects of drugs acting on tumor vasculature, namely anti-angiogenic and vascular disrupting agents. Ultra-high-field MRI allows higher-resolution scanning for DCE-MRI while maintaining an adequate signal-to-noise ratio. However, increases in susceptibility effects, combined with decreases in longitudinal relaxivity of gadolinium-based contrast agents (GdCAs), make DCE-MRI more challenging at high field. The aim of this work was to explore the feasibility of using DCE-MRI at 11.7 T to assess the tumor hemodynamics of mice. Three GdCAs possessing different molecular weights (gadoterate: 560 Da, 0.29 mmol Gd/kg; p846: 3.5 kDa, 0.10 mmol Gd/kg; and p792: 6.47 kDa, 0.15 mmol Gd/kg) were compared to see the influence of the molecular weight in the highlight of the biologic effects induced by combretastatin A4 (CA4). Mice bearing transplantable liver tumor (TLT) hepatocarcinoma were divided into two groups (n = 5-6 per group and per ...
Envision uses non-ionic contrast media. This is the safest intravenous contrast media available.. Sometimes an injection of contrast media is indicated to enhance diagnostic accuracy of the examination and enhance the quality. Following an injection of contrast media, you may experience a sensation of heat, an unusual taste or smell and a tingling sensation in the pelvic area. These symptoms are common and very transient. The contrast is eliminated from the body by the kidneys and is excreted in the urine within hours of the initial injection. Patients are encouraged to drink additional clear fluids following their examination to assist in the filtration of the kidneys.. Occasionally, patients can experience minor allergic reactions such as hives. In rare cases, a major allergic reaction can occur. Envision staff are trained in the management of allergic reactions and all sites that administer intravenous contrast media are equipped with emergency medications and equipment, should a patient ...
Although effective in promoting the prevention of SCD, current risk stratification strategies in HCM patients do not identify all at-risk patients, largely as a result of the substantial heterogeneity in clinical and phenotypic expression of this genetic disease.2,3,5,8,42 Because SCD can occur in HCM patients considered to be at low risk, identification of additional markers to allow more precise selection of those patients who may benefit from primary prevention ICD therapy represents a major clinical aspiration.3,28 Recently, considerable interest in using contrast-enhanced CMR to improve the risk stratification model has emerged.43-48 However, available data on the prognostic value of CMR do not provide an opportunity to specifically predict SCD risk for individual HCM patients.28,29 In the present large, multicenter HCM cohort, we have investigated LGE as a predictor of SCD and other adverse disease consequences among a predominantly lower-risk cohort of HCM patients.. Our data show that in ...
Contrast Media Injectors (Diagnostic Imaging) - Global Market Analysis and Forecast Model has complete details about market of Contrast Media Injectors (Diagnostic Imaging) industry, Contrast Media Injectors (Diagnostic Imaging) analysis and current trends. Contrast Media Injectors (Diagnostic Imaging) - Global Market Analysis and Forecast Model Summary Contrast Media Injectors (Diagnostic Imaging) - Global Market Analysis and Forecast Model is built to visualize quantitative market trends within Diagnostic Imaging therapeutic area. Contrast Media Injectors are devices used to inject contrast medi.
Early buyers will receive 10% customization on reports.. This report studies the global contrast media/contrast agentsmarket for the forecast period of 2016 to 2021. This market is expected to reach a value of USD 5.44 Billion by 2021, from an estimated value of USD 4.46 Billion in 2016, at a CAGR of 4.1%.. The prominent players in the global contrast media/contrast agents market include Bayer HealthCare (Germany), GE Healthcare (U.S.), Guerbet Group (France), and Bracco Imaging S.p.A. (Italy). These companies hold a dominant position in the contrast media/contrast agents market mainly due to their well-established presence in the field of genomics, presence in over 50 countries, high R&D investments, and strong sales and distribution force. Other players operating in this market include Lantheus Medical Imaging (U.S.), nanoPET Pharma GmbH (Germany), CMC Contrast AB (Sweden), Daiichi Sankyo (Japan), and Subhra Pharma Private Limited (India).. The global contrast media/contrast agentsmarket has ...
Dynamic susceptibility contrast (DSC) perfusion imaging has been in clinical use for various indications, including characterization and grading of intracranial neoplasms. However, several technical factors can lead to pitfalls in image interpretation. This review discusses the extraction of T1 and T2* information from mean curve analysis of DSC perfusion imaging of various brain tumors, which provides further insights into tumor biology and, thus, may be useful in the differential diagnosis of such tumors. Indeed, by looking at the mean time-signal intensity curve from the tumor bed in addition to the rCBV maps, it is possible to obtain further inferences of capillary density and lesion leakiness. When dynamic contrast enhanced (DCE) T1 perfusion is not available, DSC perfusion with mean curve analysis appears to be a valid alternative for characterizing various brain neoplasms in a routine clinical setting.. El texto completo de este artículo está disponible en PDF ...
A method was devised for obtaining dynamic contrast-enhanced T1-weighted and relaxation rate (delta R2*) images simultaneously to evaluate regional hemodynamics of the brain tumors. On a 1.5-T MR system, dual dynamic contrast-enhanced images were obtained using a gradient echo (dual echo fast field …
Many CT studies require intravenous contrast agent. This is a special fluid containing iodine that enhances the blood vessels and certain organs and allows them to be better visualised, highlighting any abnormalities. If your examination requires an intravenous contrast injection, you will be asked whether you have a history of allergies or asthma; and whether you are on diabetic medication. Oral contrast media are not usually required for CT studies of the brain and spine. ...
Pathologic hyperpermeability exists in the spectrum of disease states, including neuro-ischemic, neuro-inflammatory and neuro-oncological. To-date the characterization of disease pathology with T 1 -weighted quantitative dynamic contrast-enhanced magnetic resonance imaging has relied on the study of modeled microvascular parameters such as diseased tissue transvascular flow rates of small molecule paramagnetic imaging agents with short plasma half-lives, based on which it is difficult to assess the specific nature of the disease state. Another type of T 1 -weighted quantitative dynamic contrast-enhanced magnetic resonance imaging involves the use of paramagnetic heavy metal-chelated dendrimer nanoparticles that possess longer plasma half-lives with pre-determined molar relaxivities to quantitatively image concentration of macromolecular contrast agent accumulation over time in hyperpermeable pathology such as solid tumor tissue with the
OBJECTIVES The aim of this study was to investigate the feasibility of using contrast-enhanced ultrasound (CEUS) in experimental breast cancer bone metastases and its utilization for assessment of early antiangiogenic treatment response in these lesions. MATERIALS AND METHODS Nude rats bearing bone metastases (n = 20) were treated with the antiangiogenic tyrosine kinase inhibitor sunitinib daily from days 30 to 35 after MDA-MB-231 tumor cell inoculation (n = 10) and compared with sham-treated controls (n = 10). Imaging with ultrasound (US) and magnetic resonance imaging (MRI) was performed on days 30, 32, and 35 after tumor cell inoculation to determine tumor volume and parameters of vascularization in bone metastases. Contrast-enhanced US images were used to calculate wash-in and wash-out values, peak enhancement, and area under the curve from time intensity curves. In addition, a quantitative analysis software was used to determine regional blood volume and flow as well as filling times within bone
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ECCO - European Crohn´s and Colitis Organisation. The European Crohn\s and Colitis Organisation is a highly active non-profit association focusing on Inflammatory Bowel Diseases (IBD).
CMR adenosine first pass perfusion yields excellent results for the detection of significant coronary artery disease. As in patients after coronary artery bypass grafts (CABG) myocardial perfusion is more complex and additionally the kinetic of a first pass bolus may by altered due to different distances through the bypasses and/or native vessels, this patient group has been excluded from most published studies. Parameters like speed of contrast wash-in (upslope, time to 50% or peak enhancement) and peak enhancement are indirectly used for visual analysis and may be altered post CABG imitating perfusion defects without significant stenosis. In this case, adenosine perfusion would be an inadequate diagnostic test. ...
Microparticles which are less than 12 μm in size and are formed of or comprise a solid lipophilic group-containing compound having an HLB value less than about 20 produce a long lived ultrasonically echogenic entity in aqueous liquid and are useful as left heart ultrasonic contrast image enhancing agents. Contrast media for ultrasonic diagnostics comprising a liquid vehicle containing (a) suspended therein microparticles of a mixture of at least one (C8 -C20)-fatty acid and at least one solid that is not a surfactant and (b) microbubbles, are especially effective upon ultrasonic imaging after intravenous administration, for the contrasting of both the right heart and left heart, of the myocardium, as well as other organs, such as liver, spleen, and kidneys.
Absolute cerebral perfusion parameters were obtained by dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) carried out using different contrast-agent administration protocols. Sixteen healthy volunteers underwent three separate DSC-
Contrast-enhanced magnetic resonance angiography (MRA) employs the use of blood pool contrast agents (CA) such as gadolinium (Gd3+) complexes that allow for delayed phase arterial
ESUR GUIDELINES ON CONTRAST MEDIA 7.0 PDF - ESUR GUIDELINE*: GADOLINIUM BASED. CONTRAST MEDIA AND NEPHROGENIC. SYSTEMIC Incidence of NSF: % in at-risk subjects. Contrast media · › Contrast media · ›
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Image acquisition strategies. Principal contrast mechanisms in MRI emerge from the relaxation properties of tissue water (or fat) hydrogen nuclei in the scanner magnetic field after undergoing radiofrequency excitation. These properties can be manipulated to reflect features of the molecular and physiologic environment of a tissue. T1-weighted images emphasize the rate (different for different tissue types) at which energy is redistributed between these nuclei and the tissue as a whole. T2*-weighted images emphasize the different rates at which the same nuclei lose phase coherence with one another and the way that this process is affected by local variations in field strength due to differences in magnetic susceptibility between tissues. Conventional gadolinium chelate-based contrast media affect T1-weighted images causing a signal increase, and T2*-weighted images causing a signal decrease.. Nearly all clinical DCE-MRI is done at 1.5 T. The data have a typical spatial resolution of a few ...
Dynamic Contrast-Enhanced Magnetic is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. The method assists
Contrast-induced nephropathy (CIN) is defined as the impairment of renal function and is measured as either a 25% increase in serum creatinine (SCr) from baseline or 0.5 mg/dL (44 µmol/L) increase in absolute value, within 48-72 hours of intravenous contrast administration.
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We describe here in a large group of patients qualitative and semiquantitative DCE-MRI parameters that distinguish sMM from normal controls. We also provide evidence that this technique can identify a distinct patient population in NRC that presents with a pathologic DCE-MRI. Referring to this, pathologic findings according to our analysis were defined by a pattern of strongly increased microcirculation (diffuse variant), focal hotspots in the investigated area (focal pattern), or by an amplitude A above the upper limit of normal controls. It has to be mentioned that a diffuse variant pattern cannot be distinguished from a focal pattern affecting the whole vertebra, which may explain in part why those two patterns seem to seem exclusively in the same, namely the symptomatic patient group.. Different patterns of bone marrow involvement of MM in conventional as well as DCE-MRI have been described concordantly by different authors (14, 23, 29, 30). Diffuse distribution of microcirculation was found ...
We read with great interest the article by Jablonowski et al. (1) showing that contrast-enhanced cardiac magnetic resonance (ce-CMR) overestimates infarct size at 6 h post-reperfusion compared with pathology and that infarct imaging timing by ce-CMR is critical. Although this is not an entirely new finding, the careful and meticulous work performed by the authors demonstrates the rapidly changing nature of acute infarction and reperfused myocardial tissue (2). If this experimental work focuses precisely on infarct sizing, the reader is left with several open questions.. On observation of the different figures from this article (Figures 3 and 6), there is a 50% reduction of infarct size by ce-CMR, whereas there is a 26% increase in myocardial salvage and a 30% reduction in extracellular volume by pathology in the infarcted myocardium and adjacent areas between day 0 and day 7. In this rapid series of myocardial tissue changes, it is hard for the reader to understand that the same changes do not ...
Objective. We aimed to determine whether contrast-enhanced ultrasonography can predict the effects of neoadjuvant chemotherapy on breast cancer.. Methods. The clinical responses of 63 consecutive patients with breast cancer (T1-4, N0-1, M0) to neoadjuvant chemotherapy between October 2012 and May 2015 were assessed using contrast-enhanced magnetic resonance imaging, positron emission tomography/computed tomography and contrast-enhanced ultrasonography. Perfusion parameters for contrast-enhanced ultrasonography were created from time-intensity curves based on enhancement intensity and temporal changes to objectively evaluate contrast-enhanced ultrasonography findings. The sensitivity, specificity and accuracy of contrast-enhanced ultrasonography, magnetic resonance imaging and positron emission tomography/computed tomography to predict a pathological complete response were compared after confirming the pathological findings of surgical specimens.. Results. Twenty-three (36.5%) of the 63 patients ...
Looking for online definition of negative contrast in the Medical Dictionary? negative contrast explanation free. What is negative contrast? Meaning of negative contrast medical term. What does negative contrast mean?
Contrast-induced acute kidney injury (CI-AKI), also known as contrast-induced nephropathy, is a common complication of intra-arterial administration of iodinated radiographic contrast medium (IRCM) that may prolong the duration of hospitalization and increase the risk of death (1,2). CI-AKI is characterized by an increase in serum creatinine beginning within the first 24 h of IRCM exposure and peaking at up to 5 days after exposure. CI-AKI is defined most commonly as a rise in serum creatinine concentration ≥0.5 mg/dl or 25% above baseline assessed 48 to 72 h after exposure to contrast (1,2). More recently, the Acute Kidney Injury Network defined CI-AKI as a rise in serum creatinine of ≥0.3 mg/dl above baseline with oliguria (1).. Patients with chronic kidney disease (CKD) are vulnerable to CI-AKI, particularly in the presence of risk factors such as diabetes mellitus and clinical states associated with decreased renal perfusion (1,2). McCullough (1) proposed a pathophysiologic sequence for ...
Hilmi Umut nal, Yal n Ba aran, Hadim Ako lu. Contrast-induced acute kidney injury/contrast-induced nephropathy may be related to additional risk factors. Anatol J Cardiol. 2018; 19(2): 155- ...
TY - JOUR. T1 - CT colonography with intravenous contrast material. T2 - Varied appearances of colorectal carcinoma. AU - Silva, Alvin C. AU - Hara, Amy K.. AU - Leighton, Jonathan A. AU - Heppell, Jacques P.. PY - 2005/9. Y1 - 2005/9. N2 - Computed tomographic (CT) colonography is a noninvasive, rapidly evolving technique that has been shown in some studies to be comparable with conventional colonoscopy for the screening of colorectal cancer. Because colorectal cancer has a widely varying appearance at both endoscopy and CT colonography, familiarity with the gamut of morphologic appearances can help improve interpretation of the results. The addition of intravenous contrast material to CT colonography can aid differentiation of true colonic masses from pseudolesions such as residual stool and improves the depiction of enhancing masses that might otherwise be obscured by residual colonic fluid. In contrast to staging of most other tumors, staging of colorectal carcinoma depends more on the depth ...
TY - JOUR. T1 - Measuring tumor perfusion in control and treated murine tumors. T2 - Correlation of microbubble contrast-enhanced sonography to dynamic contrast-enhanced magnetic resonance imaging and fluorodeoxyglucose positron emission tomography. AU - Niermann, Kenneth J.. AU - Fleischer, Arthur C.. AU - Huamani, Jessica. AU - Yankeelov, Thomas E.. AU - Kim, Dong W.. AU - Wilson, Wendy D.. AU - Hallahan, Dennis E.. PY - 2007/6. Y1 - 2007/6. N2 - Objective. The purpose of this study was to evaluate the ability of dynamic microbubble contrast-enhanced sonography (MCES), in comparison with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and fluorodeoxyglucose positron emission tomography (FDG-PET), to quantitatively characterize tumor perfusion in implanted murine tumors before and after treatment with a variety of regimens. Methods. Seventeen mice with Lewis lung carcinoma implants were categorized to control, radiation therapy alone, antiangiogenic chemotherapy alone, and ...
Adverse reactions to intravenous iodinated contrast media may be classified as general and organ-specific, such as contrast-induced nephrotoxicity. General adverse reactions may be subclassified into acute and delayed types. Acute general adverse reactions can range from transient minor reactions to life-threatening severe reactions. Non-ionic contrast media have lower risk of mild and moderate adverse reactions. However, the risk of fatal reactions is similar for ionic and non-ionic contrast media. Adequate preprocedure evaluation should be performed to identify predisposing risk factors. Prompt recognition and treatment of acute adverse reactions is crucial. Risk of contrast induced nephrotoxicity can be reduced by use of non-ionic contrast media, less volume of contrast, and adequate hydration. The radiologist can play a pivotal role by being aware of predisposing factors, clinical presentation, and management of adverse reactions to contrast media.
TY - JOUR. T1 - Intravenous contrast material exposure is not an independent risk factor for dialysis or mortality. AU - McDonald, Robert. AU - McDonald, Jennifer S. AU - Carter, Rickey E.. AU - Hartman, Robert P.. AU - Katzberg, Richard W.. AU - Kallmes, David F. AU - Williamson, Eric E.. PY - 2014/12/1. Y1 - 2014/12/1. N2 - Purpose: To determine the risk of emergent dialysis and short-term mortality following intravenous iodinated contrast material exposure.Materials and Methods: This single-center retrospective study was HIPAA compliant and institutional review board approved. All contrast material-enhanced (contrast group) and unenhanced (noncontrast group) abdominal, pelvic, and thoracic computed tomography scans from 2000-2010 were identified. Patients in the contrast and noncontrast groups were compared following propensity score-based 1:1 matching to reduce intergroup selection bias. Patients with preexisting diabetes mellitus, congestive heart failure, or chronic or acute renal failure ...
Barium Sulfate - solvaySolvay Fluorides, LLC does not sell barium sulfate directly to consumers. . odorless powder. . Exposure can occur at either a barium sulfate manufacturing facility, or . personal protective equipment such as gloves and boots, respiratory.barium sulfate powder production equipment barium sulfate powder production,Patent US4588574 - Process for the preparation of barium sulfate of .May 13, 1986 . Barium sulfate suitable for the preparation of radiographic contrast agents of . Try the new Google Patents, with machine-classified Google Scholar .. More specifically, the inventive process for producing barium sulfate which . Barium sulfate powder of a particle size of 1 to 3 μm is heated for 90 minutes ...
The iodine atom, with its relatively high atomic weight, attenuates x-rays and is used in most intravascular contrast agents today. Iodines K shell binding energy of 33.2 keV is ideal for x-ray photon absorption. Covalent bonding of 3 iodine atoms to a benzene ring at the 2, 4, and 6 position-the basic structure of all iodinated contrast agents (Fig. 18-1)-allows iodine to be delivered intravascularly, free of the side effects of free iodine, and also increases the effective molecular concentration of iodine, improving the ability to attenuate x-rays.1 An iodine concentration of 320 to 370 mg/mL is optimal for angiographic studies. Although all iodinated contrast agents use this basic benzene ring structure, the number of rings per molecule (monomers or dimers) and the side chains at the 1, 3, and 5 positions give each of them unique chemical properties.2 ...
Background: Efficacy of intravenous (IV) volume expansion in preventing contrast-induced acute kidney injury (CI-AKI) is well known. However, the role of oral hydration has not been well established. The aim of this work was to evaluate the efficacy of oral hydration in preventing CI-AKI. Methods: We prospectively randomized 225 patients undergoing coronary angiography and/or percutaneous coronary intervention in either oral hydration or IV hydration groups. Patients who have at least one of the high-risk factors for developing CI-AKI (advanced age, type 2 diabetes mellitus, anemia, hyperuricemia, a history of cardiac failure or systolic dysfunction) were included in the study. All patients had normal renal function or stage 1-2 chronic kidney disease. Patients in the oral hydration group were encouraged to drink unrestricted amounts of fluids freely whereas isotonic saline infusion was performed by the standard protocol in the IV hydration group. Results: CI-AKI occurred in 8/116 patients ...
Pharmacological interventions for the prevention of contrast-induced acute kidney injury in high-risk adult patients undergoing coronary angiography: a systematic review and meta-analysis of randomised controlled trials ...
TY - JOUR. T1 - Peripheral contrast-enhanced MR angiography at 3.0T, improved spatial resolution and low dose contrast. T2 - Initial clinical experience. AU - Nael, Kambiz. AU - Krishnam, Mayil. AU - Nael, Ali. AU - Ton, Anthony. AU - Ruehm, Stefan G.. AU - Finn, J. Paul. PY - 2008/7/14. Y1 - 2008/7/14. N2 - To investigate a high spatial resolution peripheral contrast-enhanced MR angiography (CE-MRA) protocol, applying a dedicated multi-channel array coil and accelerated parallel acquisition at 3.0T in evaluation of patients with peripheral vascular disease. Twenty patients with peripheral vascular disease underwent multi-station high spatial resolution peripheral CE-MRA at 3T. The image quality, presence of venous contamination, image noise, and artifact were evaluated by 2 radiologists independently. Assessment of arterial disease for 540 arterial segments was performed, and findings were correlated with conventional catheter angiography in 10 patients. All studies were yielded high diagnostic ...
Background: Myocardial late gadolinium enhancement (LGE) on Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) of patients (pts) with hypertrophic cardiomyopathy (HCM) may indicate intra-myocardial fibrosis. We explored whether the presence and extent of LGE on CE-MRI among pts with HCM predicted ventricular arrhythmogenicity, and decreased survival.. Methods: 424 HCM pts [age = 55 ± 16 years (range 2 - 90), 41% females], without prior history of septal ablation/myectomy, underwent CE-MRI (GE 1.5T) during a 6-year period. We compared the presence and amount of LGE with degree of ventricular ectopy on Holter ECG (available in 220 pts) recorded during the same time period of the CE-MRI. All cause death and appropriate, VF-terminating ICD therapies were then recorded during a mean follow-up of 34 ± 14 months (range 7 - 85).. Results: 239 pts (56%) had LGE ranging from 0.4 - 65% of the myocardium. LGE -positive pts were more likely to have non-sustained ventricular tachycardia on Holter ECG ...
Researchers examined iodinated contrast media use and allergic reactions in almost 200,000 patients. Family history as well as previous individual history of reaction to iodinated contrast agents suggests a genetic predisposition. Half of the approximately 88 million CT scans conducted each year in the U.S. include the use of iodinated contrast media.
The objective of our study was to investigate whether dynamic contrast-enhanced MRI (DCE-MRI) can detect differences and potential adaption in single-kidney parenchymal volume, blood flow, glomerular filtration rate (GFR), and filtration fraction in the remaining kidney of healthy donors compared with nondonors. Further, we evaluated the agreement in donor GFRs measured using DCE-MRI versus serum clearance of iohexol.. Twenty living kidney donors and 20 healthy control subjects underwent DCE-MRI and iohexol GFR. Renal parenchymal volume was assessed from maximum-signal-intensity maps. Single-kidney MRI measurements of blood flow and GFR were derived from parenchymal signal intensity-time curves fitted to a two-compartment filtration model. The Student t test, Pearson correlation coefficient, mean differences, and limits of agreement were applied to analyze MRI measurements between groups and agreement with iohexol GFR.. MRI findings showed significantly higher blood flow (difference in mean ...
Recent studies have suggested a low potential risk for contrast medium-induced kidney injury in patients with relatively normal renal function. However, whether contrast media cause additional deterioration of renal function in patients with acute kidney injury (AKI), including those with sepsis-associated AKI, remains unclear. This study aimed to evaluate the effect of contrast media on renal function and mortality in patients with sepsis who already had AKI. We performed a propensity score-matched historical cohort study in the medico-surgical intensive care unit of Jichi Medical University Hospital. Adult patients who were diagnosed with sepsis and AKI were enrolled. Records from our sepsis database from 2011 to 2017 were examined. Septic patients with AKI who received contrast media within 24 h of admission (C group) were matched 1:1 with septic patients who did not receive contrast media (NC group). The primary outcome was deterioration of kidney function (DRF), which was defined as an elevation of
T1 mapping of the myocardium: intra-individual assessment of post-contrast T1 time evolution and extracellular volume fraction at 3T for Gd-DTPA and Gd-BOPTA : Purpose Myocardial T1 relaxation time (T1 time) and extracellular volume fraction (ECV) are altered in patients with diffuse myocardial fibrosis. The purpose of this study was to perform an intra-individual assessment of normal T1 time and ECV for two different contrast agents. Methods A modified Look-Locker Inversion Recovery (MOLLI) sequence was acquired at 3 T in 24 healthy subjects (8 men; 28
The global Microbubbles/Ultrasound Contrast Agents Market will grow at a CAGR of 25.2% from 2018 to 2024 to reach USD 1,584.5 million by 2024, according to the latest publication from Meticulous Research®. The global microbubbles/ultrasound contrast agents market is driven by various factors such as advancement in...
is able to provide quantitative data regarding the anatomical and physiological features of each specific organ. Magnetic resonance imaging is a non-invasive method, but contrast agents are necessary to enhance the visualization of inaccessible organs in some organs such as gastrointestinal [GI] imaging. Various types of contrast agents have been used in studies including intravascular administration and oral materials. Oral contrast agents can be the artificial materials or natural factors. Natural contrast agents consist of fruit juice or pulps. Some advantages have been reported regarding the natural types of contrast agents over the artificial agents including better taste and tolerability. We briefly reviewed the different types of contrast agents and focused on the studies in which natural oral contrast agents used to investigate their efficacy in increasing the gastrointestinal magnetic resonance imaging clarity ...
TY - JOUR. T1 - Gastric cancer with synchronous and metachronous hepatic metastasis predicted by enhancement pattern on multiphasic contrast-enhanced CT. AU - Tsurumaru, Daisuke. AU - Nishimuta, Yusuke. AU - Muraki, Toshio. AU - Asayama, Yoshiki. AU - Nishie, Akihiro. AU - Oki, Eiji. AU - Honda, Hiroshi. PY - 2018/11. Y1 - 2018/11. N2 - Objective: The purpose of this study was to examine the relationship between the CT features of the primary-site gastric cancer and the concurrent existence or postoperative recurrence of hepatic metastasis. Materials and methods: From January 2013 to July 2016, 125 patients with advanced gastric cancer who were evaluated by gastroscopy and contrast-enhanced CT at our institution were included. Eleven patients had hepatic metastasis at the time of diagnosis (synchronous hepatic metastasis). Five patients had hepatic recurrence after surgery (metachronous hepatic metastasis, median follow-up period of 313 days), and another 56 patients had no hepatic recurrence ...
Ultrasound contrast agents (UCAs) have been in the echocardiographic toolbox for many years. Two such agents (Definity [Lantheus Medical Imaging, North Billerica, Massachusetts] and Optison [GE Healthcare, Princeton, New Jersey]) are approved by the U.S. Food and Drug Administration (FDA) and are commercially available for left ventricular cavity opacification in patients with technically difficult echocardiograms. The greater, still unrealized value of these unique erythrocyte tracers, however, resides in their ability to depict the spatial distribution of myocardial perfusion and to quantify intramyocardial blood volume, properties that render UCAs ideal for the detection and localization of coronary artery disease (CAD).. UCAs have had a checkered history, particularly with respect to myocardial perfusion imaging. The literature is replete with studies showing the promise of myocardial contrast echocardiography (MCE) for CAD detection (1,2). Studies in dogs dating back to the early 1980s ...
Magnetic Resonance Angiography (MRA) of the peripheral arteries has become essential in the diagnosis and follow-up of peripheral arterial disease.. In clinical routine, the acquisition uses intravenous injection of a Gadolinium based contrast agent (gadolinium chelates).. Initially, contrast enhanced MR angiography (CE-MRA) was recommended for diabetic patients, elderly patients and\or patients with chronic renal insufficiency presenting a contraindication to CT angiography using iodized contrast agent injection.. However, the increase in nephrogenic systematic fibrosis clinical cases, which would be secondary to gadolinium chelates injection, in patients with chronic renal insufficiency has restricted the use of CE-MRA. More than 500 cases were described to date in the world.. Its occurrence is currently estimated around 4 % for patients in terminal chronic renal insufficiency and its mortality around 30 %.. According to the recommendations of AFSSAPS from August, 2007, two gadolinium contrast ...
Dr. Songping Huang: Synthesis of Nanoparticle-Based MRI/CT Contrast Agents and Gallium-Based Anticancer Drugs Chemistry & Biochemistry | The current research interests of Huang Group include development of nanoparticle-based contrast agents and molecular probes for in vivo imaging using MRI, CT and PET modalities and synthesis of novel biocompatible inorganic nanomaterials as
Patients receiving dialysis are also at theoretical risk from the osmotic load imposed by intravascular iodinated contrast medium because they cannot clear the excess intravascular volume. This osmotic load can theoretically result in pulmonary edema and anasarca. To mitigate this possible risk, contrast medium dosing should be as low as necessary to achieve a diagnostic result (as in all patients). However, complications were not observed in a study of dialysis patients who received intravascular nonionic iodinated contrast medium, though the number of patients was small. ...
Background: Coronary angiography is associated with a 4-15% chance of contrast-induced nephropathy (CIN). While the cause of CIN is still not understood, renal ischemia and free radical effects on tubular epithelial cells are thought to be responsible. In addition to increased hydration, the antioxidant properties of sodium bicarbonate are thought to decrease the direct toxic effects seen in CIN. The question of this treatments efficacy has been asked since its inception, and no definitive conclusion has been reached. The purpose of this systematic review is to compare and contrast the most current randomized trials, assessing the quality of the studies involved, and to give a practicing clinician a more complete understanding of the outcomes. Methods: Exhaustive search of available medical literature from 2006 to the present for randomized control trials regarding contrast-induced nephropathy in patients undergoing non-emergent coronary angiography. The reviewed studies examined the significance of
Compared to commercially available contrast agents under the same experimental conditions, these new cationic agents are three times more sensitive for imaging cartilage, said Mark W. Grinstaff, Boston University Professor of Chemistry and Biomedical Engineering who led the team with Brian D. Snyder, MD, Ph.D. an orthopedic surgeon at Childrens Hospital and Harvard Medical School. Snyder noted that the ability to acquire information about localized GAG content, morphology and cartilage thickness on tissue samples will, in the future, aid in the diagnosis and treatment of osteoarthritis. And while the data presented a compelling case for continued development of cationic CT contrast agents, the research team cautioned that the suitability for in vivo applications remains to be determined, adding that toxicity levels and radiation dosage will be the focus of future studies. However, the ability to characterize ex vivo cartilage samples is clearly evident, the study concludes. Currently ...
TY - JOUR. T1 - Brain gadolinium deposition, hyperintense MRI signals, and resonance contrast agents. AU - Costa, A.. AU - Ronchi, A.. AU - Pigatto, P.D.. AU - Guzzi, G.. N1 - Cited By :1 Export Date: 11 January 2019. PY - 2018. Y1 - 2018. U2 - 10.1016/j.mri.2018.06.001. DO - 10.1016/j.mri.2018.06.001. M3 - Article. VL - 52. SP - 137. EP - 138. JO - Magnetic Resonance Imaging. JF - Magnetic Resonance Imaging. SN - 0730-725X. ER - ...
Todays pearl reviews some of the literature and recommendations regarding the use of iodinated contrast in patients with kidney disease Will it cause an acute-on-chronic injury? Is it safe? Its long been debated what role, if any, iodinated contrast agents play in causing acute kidney injury (AKI). In the largest ED study to date, there…
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Targeted contrast-enhanced ultrasound (TCEUS) is an innovative method of molecular imaging used for detection of inflammatory biomarkers in vivo. By targeting ultrasound contrast to cell adhesion molecules (CAMs), which are known inflammatory markers within neural tissue, a more direct evaluation of neural inflammation can be made. Due to the novel nature of TCEUS, standardized methods of image analysis do not yet exist. Time intensity curve (TIC) shape analysis is currently used in magnetic resonance contrast imaging to determine temporal behavior of perfusion.
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Objectives The purpose of this study was to compare sulfur hexafluoride microbubble (SonoVue)-enhanced myocardial contrast echocardiography (MCE) with single-photon emission computed tomography (SPECT) relative to coronary angiography (CA) for assessment of coronary artery disease (CAD). Background Small-scale studies have shown that myocardial perfusion assessed by SonoVue-enhanced MCE is a viable alternative to SPECT for CAD assessment. However, large multicenter studies are lacking. Methods Patients referred for myocardial ischemia testing at 34 centers underwent rest/vasodilator SonoVue-enhanced flash-replenishment MCE, standard Tc-99m-labeled electrocardiography-gated SPECT, and quantitative CA within 1 month. Myocardial ischemia assessments by 3 independent, blinded readers for MCE and 3 readers for SPECT were collapsed into 1 diagnosis per patient per technique and were compared to CA (reference standard) read by 1 independent blinded reader. Results Of 628 enrolled patients who received ...
OBJECTIVE: For minimal invasive treatment of small renal masses, cryoablation has gained popularity. Treatment success is defined as absence of contrast enhancement on postoperative imaging of the cryoablated lesion, but contrast enhancement does not necessary equal treatment failure. This present study investigates the proportion of spontaneous resolutions after initial contrast enhancement in relation to cryoablation.. PATIENTS AND METHODS: Data were collected from a prospectively maintained clinical database containing all patients treated with primary laparoscopic and percutaneous cryoablation between August 2005 and December 2013. All images were evaluated with regard to PADUA-score, cryolesion size, contrast enhancement pattern and tissue density.. RESULTS: A total of 107 patients with a biopsy verified malignant tumor were included in the study. On postoperative imaging 33 (31%) patients presented with contrast enhancement. Spontaneous resolution was observed in 15 (45%) patients after a ...
PubMed journal article The impact of iodinated contrast agent administered during preoperative computed tomography scan on body iodine pool in patients with differentiated thyroid cancer preparing for radioactive iodine treatmen were found in PRIME PubMed. Download Prime PubMed App to iPhone, iPad, or Android
We read with great interest the article by Arevalo-Perez et al, describing the potential value of T1-weighted dynamic contrast-enhanced MR imaging (DCE-MR imaging) as a biomarker for epidermal growth factor receptor variant III (EGFRvIII) mutation in patients with glioblastoma (GBM).
Computed tomography (CT) scans are an imaging method that use x-rays to create pictures of cross-sections of the body. Many CT scans involve intravenously injected iodinated contrast agents - but they have drawbacks such as fast clearance and side effects. Due to these limitations, nano-sized iodinated CT contrast agents have been developed that can increase the circulation time and decrease the adverse effects. In addition to iodine, nanoparticles based on heavy atoms such as gold, lanthanides, and tantalum are used as more efficient CT contrast agents.
As gadolinium contrast dye lawsuits mount, a new study warns that children can experience allergic like reactions from side effects of MRI contrast agents.
P3T PA (pulmonary angiography), from Medrad, is a personalized contrast-dosing software that increases the percentage of diagnostic-quality CT pulmonary angiography (CTPA) studies to rule out pulmonary embolism (PE).. Researchers have concluded that suboptimal CTPA interpretations to rule out PE can substantially impact healthcare resource utilization and increase healthcare costs. With 30 percent of their CTPA studies showing suboptimal results, these patients were subjected to additional imaging studies and/or received medical therapy. Some patients were admitted to the hospital for further PE diagnosis considerations. None of the additional treatments or imaging modalities yielded a diagnosis of PE.. P3T PA fits into the established workflow and offers flexibility and efficiency in optimizing each patients contrast dose -- especially when operating higher-speed scanners. The P3T algorithm tailors each patients contrast protocol based on technologists touch-screen responses to unique ...
Of the 3 parameters studied, Vp was the most significant measure of tumor response. Differences in Vp mean and Vp maximum values pre- and posttreatment were significant. On average, Vp max values were approximately 1.6 times greater before treatment, which is concordant with previous work demonstrating the significantly higher vascularization of chordoma in comparison with that of adjacent normal tissues.17 Chordoma has been shown to express elevated vascular endothelial growth factor and matrix metalloproteinase-9, which may work in concert to increase angiogenesis and invasiveness and promote recurrence of chordoma and other bone cancers.18⇓-20. Ktrans was also a positive indicator of tumor response to therapy. A measure of vascular permeability, Ktrans represents the rate at which blood is transferred from the vascular compartment to the extravascular extracellular space. Therefore, unlike Vp, Ktrans is a marker of tumor leakiness rather than actual tumor vascularity. On receiving RT, ...
An 80 year old man with a history of abdominal aortic aneurysm, repaired 10 years previously, presented to the emergency room with a four hour history of severe epigastric pain. Examination demonstrated a distended, tender, but non-rigid abdomen. ECG was unremarkable. Shortly after arrival the patient suffered a sudden onset of massive haematemesis requiring replacement of large volumes of intravenous colloid and blood. Following successful resuscitation urgent endoscopy was undertaken, but failed to demonstrate a bleeding point because of large amounts of fresh blood in the stomach. Abdominal multidetector computed tomography (CT) (Siemens Forchheim, Somatom plus 4) was then performed. Axial images of the abdomen (panel A), at a level just inferior to the renal arteries, showed intravenous contrast medium in a slightly aneurysmal abdominal aorta (black solid arrow). Intravenous contrast medium is also seen outlining the inner wall of the third part of the duodenum (white arrow). An aortoenteric ...
Barium sulfate, used as a radio-opaque marker in some orthopedic bone cements, has been shown to escape into the surrounding tissues. This may present a potential hazard. In particular, phagocytic cells may be exposed to relatively high internal levels of barium once the particles have been phagocytosed. Mouse peritoneal macrophages exposed to barium sulfate for periods up to 144 hr showed a marked cytoplasmic vacuolization from which they recovered only partially. Barium sulfate did not appear to damage the cell membrane as judged by lactice dehydrogenase release. In the relatively low doses and with the periods of exposure described here, barium sulfate does not appear to present a serious toxic hazard in the short term. It is possible, however, that longer exposures and larger doses may result in the death of phagocytic cells which have ingested barium sulfate. ...
0042] Unfortunately, there are two key challenges in determining a water exchange rate that significantly limit these approaches. First, Eqn. (11) includes four parameters that determine the tissue longitudinal relaxation time, T1,tissue: T1,v, T1,ev, PS, and fv. This is partially addressed by measuring T1 in a region-of-interest (ROI) that contains only blood and in an ROI of tissue, such as gray matter, before and after administration of a contrast agent. T1,ev can be estimated from the T1 of the tissue measured before addition of a contrast agent. T1,v is the T1 determined in the blood ROI. This leaves two parameters, PS and fv, that contribute to T1,tissue in the presence of a contrast agent. Donahue and Schwarzbauer, working in animal models, addressed this problem by administering an intravascular contrast agent with a very long blood half-life. The long blood half-life allowed for a relatively unchanging steady-state T1,v. They determined T1,v and T1,tissue and then gave more contrast ...
TY - GEN. T1 - Does contrast ultrasound dispersion imaging reveal changes in tortuosity? : a comparison with acoustic angiography. AU - Panfilova, A.. AU - Mischi, M.. AU - Wijkstra, H.. AU - van Sloun, R.J.G.. AU - Demi, L.. AU - Shelton, S.. AU - Dayton, P.. PY - 2016. Y1 - 2016. N2 - Higher microvascular density with tortuous and irregular vessels are hallmarks of cancer vasculature. These alterations can be captured by contrast ultrasound dispersion imaging (CUDI) and acoustic angiography (AA) at different scales: CUDI aims at obtaining an implicit measure of structural alteration by determining the dispersion kinetics of contrast agents. At a smaller scale, AA images the vascular architecture by detecting the high-frequency components generated with ultrasound contrast agents (UCA). This work shows the performance of these techniques by imaging cancerous and control regions in 3 rat xenograft models. Furthermore, it investigates the diagnostic value of the vascular features extracted using ...
In most cases, shortly after infusion, iodinated contrast media cause a warming sensation throughout the body. In certain areas of the body this feeling is more pronounced. Patients receiving contrast media via IV typically experience a hot feeling around the throat, and this hot sensation gradually moves down to the pelvic area.. Reactions to IV dye are observed in 5% to 8% of patients who receive them. Mild reactions include a feeling of warmth, nausea, and vomiting. Generally, these symptoms occur only for a short period of time and do not require treatment. Moderate reactions, including severe vomiting, hives, and swelling, occur in 1% of patients receiving contrast media and frequently require treatment. Severe, life-threatening reactions, including anaphylaxis, occur in 0.1% of people receiving contrast media, with an expected death rate of one person in every 75,000. The most severe reactions, including death, have been reported to occur at similar rates with both types of contrast ...
MRI contrast agent and imaging of a breast cancer xenograft model". Contrast Media & Molecular Imaging. 9 (4): 313-322. doi: ...
ACR Manual on Contrast Media v10.3. 2017 (PDF). American College of Radiology. 2017. p. 6. ISBN 9781559030120. Archived (PDF) ... "Nycodenz®: A universal density gradient medium" Archived 2015-02-26 at the Wayback Machine, Axis-Shield Density Gradient Media ... Springer Science & Business Media. p. 235. ISBN 9781447117551. Archived from the original on 1 January 2017. Broe, Marc E. de; ... Iohexol, sold under the trade name Omnipaque among others, is a contrast agent used for X-ray imaging. This includes when ...
"Cholegraphic contrast medium". Medcyclopaedia. GE. Duncan, C; Riall, T (2012). "Evidence-Based Current Surgical Practice: ... A radiopaque cholegraphic (contrast) agent, usually iopanoic acid (Telepaque) or its sodium or calcium salt, is orally ... This excreted material will collect in the gallbladder, where reabsorption of water concentrates the excreted contrast. Since ...
Local news media drew attention to the contrast in enforcement. The Greensboro Police Department arrested and charged several ...
Yıldız, Sema; Kuşkonmaz, Şerife Mehlika (2016). "Effect of iodinated contrast media on thyroid: a brief review". Journal of ... The source of iodine may be from the diet, administration of the iodinated contrast for medical imaging, or amiodarone (an ... Dunne P, Kaimal N, MacDonald J, Syed AA (2013). "Iodinated contrast-induced thyrotoxicosis". CMAJ. 185 (2): 144-7. doi:10.1503/ ... In iodinated contrast administration for medical imaging, monitoring is indicated in people with thyroid disease, such as toxic ...
Gd-DTPA is classed as an acyclic, ionic gadolinium contrast medium. Its paramagnetic property reduces the T1 relaxation time ( ... "Is there a causal relation between the administration of gadolinium-based contrast media and the development of nephrogenic ... "Adverse reactions to gadolinium contrast media: a review of 36 cases". American Journal of Roentgenology. 167 (4): 847-849. doi ... Gadopentetic acid is one of the trade names for a gadolinium-based MRI contrast agent, usually administered as a salt of a ...
... an iodide based contrast medium for CT scans, and Optimark (gadoversetamide injection) a Gadolinium-Based Contrast Agent used ... for $2.3 billion 2015 - Mallinckrodt acquired Therakos for $1.325 billion 2015 - Mallinckrodt sold the Contrast Media and ... Medical Imaging products include contrast media and radiopharmaceuticals for medical imaging applications. In the fourth ... "Guerbet completes acquisition of Mallinckrodt's Contrast Media and Delivery Systems business (CMDS)". www.guerbet.com. ...
ISBN 978-0-8153-3642-6. Böhm I, Speck U, Schild HH (April 2011). "Pilot study on basophil activation induced by contrast medium ... induced by contrast medium), the BAT is of great impact. Basopenia (a low basophil count) is difficult to demonstrate as the ...
In contrast with other international media reports, Peruvian health officials downplayed the incident. Jorge López Tejada, the ...
Images are produced using contrast medium by subtracting a "pre-contrast image" or mask from subsequent images, once the ... The radiologist controls how much contrast media is injected and for how long. Smaller structures require less contrast to fill ... which avoids X-rays and nephrotoxic contrast agents. Angiography Computed tomography angiography (CTA) Contrast medium ... images are acquired by exposing an area of interest with time-controlled x-rays while injecting contrast medium into the blood ...
"The developmental history of the gadolinium chelates as intravenous contrast media for magnetic resonance". Investigative ... Common contrast agents are administered into a peripheral vein from which they are distributed throughout the circulation to ... Rawson, JV; Pelletier, AL (1 September 2013). "When to Order a Contrast-Enhanced CT". American Family Physician. 88 (5): 312-6 ... The specific imaging technique being employed will determine the characteristics of an appropriate contrast agent to increase ...
Through a catheter in the ascending aorta contrast media is injected and the resulting aortography may be used to delineate the ... Computed tomography (CT): Computed tomography after application of contrast media is usually diagnostically accurate. It shows ...
Cysteinyl leukotrienes may also play a role in adverse drug reactions in general and in contrast medium induced adverse ... Böhm, Ingrid; Speck, Ulrich; Schild, Hans (2005). "A possible role for cysteinyl-leukotrienes in non-ionic contrast media ...
In contrast the National Radio and Television Administration regulates radio and other media content. Amateur radio licensing ...
contrast media For euthanasia[edit]. See also: Barbiturate § Other non-therapeutical uses ...
contrast media For euthanasia[edit]. See also: Barbiturate. A euthanaticum is used for euthanasia and physician-assisted ...
... contrasts with the "stickiness" of aggregating media in centralized places. The original copy of the (textual, ... Digital media Internet meme New media Social media Jenkins, Ford & Green (2013). "Henry Jenkins on 'Spreadable Media,' why fans ... for media studies and marketing was Spreadable Media (2013) by media academics and industry experts Henry Jenkins, Sam Ford, ... A "medium" is any tool that can be used by anybody to deliver various forms of media (any information, a picture, etc.) to an ...
In radiological units latex allergy may mimic contrast medium allergy Type IV allergy, also known as allergic contact ... Böhm, Ingrid (2010). "Latex allergy in patients suspected for contrast medium hypersensitivity: A neglected differential ...
Contrast mediums such as ioversol increases the nephrotoxicity and otoxicity caused by amikacin. Amikacin can decrease the ...
The media quickly dubbed the bloc the "COPE Light" councillors (in contrast to the "COPE Classic" councillors). In 2005, the ...
The alluring result is cool, reloaded." By contrast, Derek Miller of Pitchfork Media noted that "some of Kittin's lyrical ... Zinc Media, Inc. Retrieved 2011-04-12. CS1 maint: discouraged parameter (link) Chart Log UK : M - My Vitriol Zobbel. Retrieved ... Pitchfork Media review Archived 2008-03-14 at the Wayback Machine "PopMatters review". Archived from the original on 2009-10-10 ... Zinc Media, Inc. Retrieved 2011-04-12. CS1 maint: discouraged parameter (link) Miss Kittin - Reqiem for a Hit Ultratop. ...
These investigations may be used with contrast media (barium enema) which may show the associated mucosal abnormalities. This ... Rectal intussusception by contrast is not life-threatening. Intussusceptum refers to the proximal section of rectal wall, which ... In contrast to other methods, STARR does not correct the descent of the rectum, it removes the redundant tissue. The technique ...
See chiaroscuro for a discussion of the uses of such contrasts in visual media. Color paints are mixed together to create ... Artists use darkness to emphasize and contrast the presence of light. Darkness can be used as a counterpoint to areas of ... The dictionary definition of darkness at Wiktionary Quotations related to Darkness at Wikiquote Media related to Darkness at ...
... (INN; trade name Optiray) is an organoiodine compound that is used as a contrast medium. It features both a high ...
... Synthesis provides intermediates for non-ionic X-ray contrast media, and has dedicated plants for this market. The ...
Contrast radiography uses a radiocontrast agent, a type of contrast medium, to make the structures of interest stand out ... Yu SB, Watson AD (September 1999). "Metal-Based X-ray Contrast Media". Chemical Reviews. 99 (9): 2353-78. doi:10.1021/cr980441p ... An iodine-based contrast is injected into the bloodstream and watched as it travels around. Since liquid blood and the vessels ... Contrast agents are required in conventional angiography, and can be used in both projectional radiography and computed ...
Media in category "Medical imaging". This category contains only the following file. ... Contrast-enhanced. *3D ultrasound. *Endoscopic ultrasound. *Emergency ultrasound *FAST. *Pre-hospital ultrasound ...
In contrast to the heated debate in the media, players and administrators refrained from publicly questioning or condemning ... By contrast to the strident condemnation of Meckiff in the English press, Australian opinion was mixed. The former Test opener ... At the time, players were not allowed to talk to the media during the season, and Meckiff was upset because he could not rebut ... During the late 1950s and early 1960s, there had been a media frenzy about the perceived prevalence of illegal bowling actions ...
In this case the gas is referred to as the negative contrast medium. Traditionally the images produced with barium contrast are ... Barium meal examination showing the stomach and duodenum in double contrast technique with CO2 as negative contrast medium ... A contrast medium, usually a radiocontrast agent such as barium sulfate mixed with water, is ingested or instilled into the ... Barium sulfate as a contrast medium in medical practice was introduced largely as a result of the works of Krause a director of ...
The contrast medium is injected into a vein, and images are acquired both pre-contrast and during the first pass of the agent ... Whereas most of techniques in MRA rely on contrast agents or flow into blood to generate contrast (Contrast Enhanced techniques ... Also, contrast media used for MRI tend to be less toxic than those used for CT angiography and catheter angiography, with fewer ... Unfortunately, the use of gadolinium-based contrast media can be dangerous if patients suffer from poor renal function. To ...
This is in contrast to type 1 diabetes in which there is an absolute insulin deficiency due to destruction of islet cells in ... Media from Wikimedia Commons *. News from Wikinews *. Quotations from Wikiquote *. Texts from Wikisource ...
However, in contrast to the countries in the Anglo-Saxon system category, this is a much more widespread network of collective ... Wikimedia Commons has media related to Trade union.. Wikiquote has quotations related to: Trade union. ... In contrast, in several European countries (e.g. Belgium, Denmark, the Netherlands and Switzerland), religious unions have ... Ireland and the UK belong to this category, and in contrast to the EU core countries above, these countries first joined the EU ...
In contrast, convolutional codes are typically decoded using soft-decision algorithms like the Viterbi, MAP or BCJR algorithms ... Sphere Packings, Lattices and Groups, By J.H. Conway, N.J.A. Sloane, Springer Science & Business Media, 9 Mar 2013 - ... In contrast to classical block codes that often specify an error-detecting or error-correcting ability, many modern block codes ...
In contrast, other approaches may be partially recognized and others have no regulation at all.[152] In some cases, promotion ... This fact is often overlooked by media or intentionally kept hidden, with alternative practice being portrayed positively when ... Traditional medicine refers to the pre-scientific practices of a certain culture, in contrast to what is typically practiced in ... In addition, in most countries, alternative therapies (in contrast to pharmaceuticals) can be marketed without any proof of ...
In contrast, a French braid starts with three small sections of hair near the crown of the head, which are then braided ...
In contrast to Khrushchev's interpretation of Marxism-Leninism, Sâr and his comrades sought to develop their own, explicitly ... Media from Wikimedia Commons *. Quotations from Wikiquote *. Data from Wikidata *A meeting with Pol Pot. Elizabeth Becker of ...
is different from the average dielectric constant of the medium ϵ. ¯. {\displaystyle {\bar {\epsilon }}}. , then any incident ... An example is the strong optical scattering by nanoporous materials.[21] The strong contrast in refractive index between pores ... Wikimedia Commons has media related to Atmospheric Rayleigh scattering.. Further reading[edit]. .mw-parser-output .refbegin{ ... Rayleigh scattering is a good approximation of the manner in which light scattering occurs within various media for which ...
2007). Na nosa lyngoage galega: a emerxencia do galego como lingua escrita na Idade Media (PDF). Santiago de Compostela: ... These contrasting attitudes have distinct political implications. Considering Galician as an independent language reduces ... Problems playing this file? See media help.. Galician-Portuguese lost its political unity when the County of Portugal obtained ... Lapesa Melgar, Rafael, El dialecto asturiano occidental en la Edad Media, Universidad de Sevilla, 1998, ...
"X-ray-Computed Tomography Contrast Agents". Chemical Reviews. 113 (3): 1641. doi:10.1021/cr200358s. PMC 3878741 . PMID ... Wikimedia Commons memiliki media mengenai Litium iodida.. *. "Webelements - Lithium Iodide". Diakses tanggal 2005-09-16.. --, ...
Wikimedia Commons has media related to Positron emission tomography.. *. Hofman, Michael S.; Hicks, Rodney J. (18 October 2016 ... Three different PET contrast agents have been developed to image bacterial infections in vivo: [18F]maltose,[19] [18F] ... PET/CT-System with 16-slice CT; the ceiling mounted device is an injection pump for CT contrast agent ...
Anatomy (medium and small scale)Edit. Medium-scale featuresEdit. Leaves are normally extensively vascularized and typically ... In contrast, many other non-seasonal plants, such as palms and conifers, retain their leaves for long periods; Welwitschia ... Berg, Linda (23 March 2007). Introductory Botany: Plants, People, and the Environment, Media Edition. Cengage Learning. ISBN ... Minor veins are more typical of angiosperms, which may have as many as four higher orders.[25] In contrast, leaves with ...
International Publications Media Group. ISBN 978-1-63267-011-3. .. *. Ebola Virus: New Insights for the Healthcare Professional ... By contrast, humans and other primates accumulate the virus throughout their body and specifically in their blood, but not very ... "North Korean state media has suggested the disease was created by the U.S. military as a biological weapon."[230] ...
However, the absence of a Bronze Age in South India, contrasted with the knowledge of bronze making techniques in the Indus ... Wikimedia Commons has media related to Harappa.. *Harappa.com. *Harappa.info. *"Harappa Town Planning"-article by Dr S. ...
White cauliflower is the most common color of cauliflower having a contrasting white head (also called "curd") surrounded by ... Wikimedia Commons has media related to Cauliflower.. *PROTAbase on Brassica oleracea (cauliflower and broccoli) ...
While, as of 2004[update], most German print media followed the reform, some newspapers, such as Die Zeit, Neue Zürcher Zeitung ... contrasts with Low German spoken in the lowlands stretching towards the North Sea. To avoid this confusion, some refer to ... The fairly common aspect of dialect use in Swiss media (both radio, internet, and television), which ranges from uncommon to ... Adherence to those standards by private individuals and companies, including the print and audio-visual media, is voluntary but ...
... in contrast to high performers, "poor performers do not learn from feedback suggesting a need to improve".[11] ...
Eubanks, Virginia, Automating Inequality: How high-tech tools profile, police, and punish the poor, Tantor Media, ISBN ... The Medicaid eligibility policy contrasts with the Journal of the American Medical Association (JAMA) guidelines which ...
Springer Science & Business Media. ISBN 9789400959316. .. *^ admin. "Raising Mallard Ducks: How to Raise Mallards In Your ... with each individual feather showing sharp contrast from buff to very dark brown, a coloration shared by most female dabbling ... The mallard is a medium-sized waterfowl species that is often slightly heavier than most other dabbling ducks. It is 50-65 cm ( ... attracted media attention in 2018 when it turned up on the island of Niue, an atypical location for mallards.[56][57] ...
... while in contrast, the leucocyte count is low at birth and falls throughout the animal's life. The neutrophil count is high at ... South Africa: Jacana Media. pp. 116-8. ISBN 978-1-4314-0871-9. .. ...
... a dictionary of discriminated synonyms with antonyms and analogous and contrasted words.. Springfield, Mass: Merriam-Webster, ... Springer Science & Business Media. p. 110. ISBN 978-3-540-44253-0. .. .mw-parser-output cite.citation{font-style:inherit}.mw- ...
Springer Science & Business Media. p. 231. ISBN 978-3-662-07677-4. . Archived from the original on 6 September 2017.. ... In contrast, if the microcomedone occurs deep within the hair follicle, this causes the formation of a whitehead (known as a ... Media related to Acne at Wikimedia Commons. *Questions and Answers about Acne - US National Institute of Arthritis and ... Medium-strength and deep-strength chemical peels are more effective for deeper atrophic scars but are more likely to cause side ...
In contrast, when the B cell lacked this asymmetric protein cluster, it was killed only 40% of the time.[36][37] ... Springer Science & Business Media. pp. 1-4. ISBN 9783034807067. Archived from the original on 2017-11-05.. ...
... medium),amount(lactose,medium). code(lac(y),permease). code(lac(z),galactosidase). temperature(low):-amount(glucose,low). ... Structured (contrast: Non-structured) *Block-structured. *Object-oriented *Actor-based. *Class-based ... amount(lactose, medium), amount(glucose, medium). }. {\displaystyle {\begin{cases}\Delta _{1}=\{{\text{amount(lactose, hi), ... amount(glucose, low)}}\}\\\Delta _{2}=\{{\text{amount(lactose, medium), amount(glucose, medium)}}\}\end{cases}}}. The decision ...
Wikimedia Commons has media related to Abortion.. *↑ Petrozza, John C (August 29 2006). "Early Pregnancy Loss". eMedicine. ... "In contrast, abortion is associated with increased risk of carcinomas of the breast. The explanation for these epidemiologic ... The person who oversaw the study later told media that given these results it would be very hard to say that having an abortion ...
One might compare and contrast trigonometry, which is really about plane trigonometry, with spherical trigonometry, hyperbolic ... Why don't math pages rely more on helpful YouTube videos and media coverage of mathematical issues? ... Media reports are typically sensationalistic. This is why they are generally avoided. ...
Media organizations[edit]. According to Media Matters for America, the "ungrammatical" and "partisan" use of the phrase ... which contrasted with his predecessor, Meade Alcorn, and with National Republican Senatorial Committee chairman Barry Goldwater ... "GOP Strategists Christen 'Democrat [sic] Party' - and the Media Comply". MediaMatters.org. Retrieved April 12, 2017 ...
Comics As a Nexus of Cultures: Essays on the Interplay of Media, Disciplines. McFarland. p. 203. ISBN 978-0-7864-3987-4.. ... turns bright brownish red with oval white spots all over in a high contrast display.[97] Displays are often reinforced by ... Springer Science & Business Media. ISBN 978-94-017-2470-8.. *. Courage, K. H. (2013). Octopus!, The Most Mysterious Creature in ...
In contrast, members of the free-software community maintain the vision that all software is a part of freedom of speech[3] and ... Patches don't have gender': What is not open in open source software." New Media & Society 14, no. 4 (2012): 669-683. ... by linking the programmer's GitHub account to their other social media accounts.[43] Between male and female programmers, the ...
Wikimedia Commons has media related to Category:Centro direzionale (Naples).. The Centro Direzionale (Naples) is a service ... In contrast to the green lawns and red bricks in their Shanghai abode, the Tange family took up residence in a thatched roof ... It was designed for three media companies: a newspaper printing plant, a radio station and a television studio. To allow for ... London, United Kingdom: Guardian News and Media Limited. ISSN 0261-3077. Retrieved 15 June 2010.. ...
... consumption continued to go down while, in contrast, the quality of sake steadily improved. ... Wikimedia Commons has media related to Sake.. Look up sake in Wiktionary, the free dictionary. ...
Safety of magnetic resonance contrast media.. Runge VM1.. Author information. 1. Department of Radiology, Scott and White ... Intravenous contrast media, specifically the gadolinium chelates, are well accepted for use in the clinical practice of ... the nephrotoxicity found with iodinated contrast media. Minor adverse reactions, including nausea and hives, occur in a low ...
... , provides key ... ... Italy Contrast Media Injectors Market Outlook to 2022 Summary GlobalDatas new report, ... Italy Contrast Media Injectors Market Outlook to 2022. Summary. GlobalDatas new report, "Italy Contrast Media Injectors Market ... Contrast Media Injectors Market Report Overview Contrast Media Injectors market size outlook report provides comprehensive ...
... the contrast media/contrast agents market is segmented into iodinated contrast media, gadolinium-based contrast media, barium- ... Contrast Media/Contrast Agents Market worth $8.68 billion by 2027 Contrast Media/Contrast Agents Market worth $8.68 billion by ... based contrast media, and microbubble contrast media. In 2017, the iodinated contrast media segment is estimated to account for ... North American contrast media/contrast agents market is expected to account for the largest share of the global contrast media/ ...
A contrast medium injector for injecting a patient with contrast medium for a CT scan is programmed to provide an injection ... A contrast medium injector for injecting a patient with contrast medium for a CT scan is programmed to provide an injection ... A contrast medium injector for injecting a patient with contrast medium for a CT scan is programmed to provide an injection ... Thus, when the outflow rate of contrast medium is balanced by the infusion rate of contrast medium by a multiphasic exponential ...
... contrast media options available to patients and radiologists, GE Healthcare today announced the ... GE Healthcare expands MRI contrast media product range in Europe with launch of macrocyclic agent ClariscanTM Clariscan builds ... GE contrast media products are used in more than 70 million procedures per year, equivalent to injection in two patients per ... Demand for contrast media has significantly increased over the past decade due to rapid procedural advancements in MR imaging, ...
Contrast media for ultrasonic diagnostics comprising a liquid vehicle containing (a) suspended therein microparticles of a ... for the contrasting of both the right heart and left heart, of the myocardium, as well as other organs, such as liver, spleen, ... 20 produce a long lived ultrasonically echogenic entity in aqueous liquid and are useful as left heart ultrasonic contrast ... Ultrasound contrast media, contrast agents containing the media and method. US20040208826 *. 26 Mar 2004. 21 Oct 2004. Bracco ...
... provider of premium market research reports announces the addition of France Contrast Media Injectors Market Outlook to 2020 ... market report to its offering France Contrast Media Injectors Market Outlook to 2020 ... France Contrast Media Injectors Market Outlook to 2020. Summary. new report, "France Contrast Media Injectors Market Outlook to ... Market size for Contrast Media Injectors market categories CT Injectors, Interventional Cardiology/Angio Injectors and MRI ...
... provides key market data on the BRIC Contrast Media Injectors market. The report provides value, in millions of US dollars, and ... MarketResearchReports.Biz announces addition of new reportBRIC Contrast Media Injectors Market Outlook to 2020to its database ... 3 Contrast Media Injectors Market, BRIC 8. 3.1 Contrast Media Injectors Market, BRIC, Revenue ($m), 2005-2020 8. 3.2 Contrast ... BRIC Contrast Media Injectors Market Outlook to 2020, provides key market data on the BRIC Contrast Media Injectors market. ...
... the nephrotoxicity found with iodinated contrast media. Min ... the nephrotoxicity found with iodinated contrast media. Minor ... Intravenous contrast media, specifically the gadolinium chelates, are well accepted for use in the clinical practice of ... Summary:Intravenous contrast media, specifically the gadolinium chelates, are well accepted for use in the clinical practice of ...
media screen and (-ms-high-contrast: active) { /* All high contrast styling rules */ } @media screen and (-ms-high-contrast: ... ms-high-contrast media feature. Describes whether the application is being displayed in high contrast mode, and with what color ... The -ms-high-contrast media feature works with the -ms-high-contrast-adjust property. ... The -ms-high-contrast media feature was introduced in Windows 8.. Examples. The following declarations will match applications ...
Water soluble iodine-based contrast media may increase the airway resistance, the pulmonary vascular resistance (PVR), and also ... Morcos S.K. (2014) Pulmonary Effects of Iodine-Based Contrast Media. In: Thomsen H., Webb J. (eds) Contrast Media. Medical ... Central venous injection of large amounts of contrast media-advantages of low osmolar contrast medium in experimentally induced ... Morcos SK (2003) Effects of radiographic contrast media on the lung. Br J Radiol 76:290-295PubMedCrossRefGoogle Scholar ...
Contrast media appear to be just as safe in children as they are in adults. The risk factors are the same and the same ... Riccabona M. (2014) Contrast Media Use in Pediatrics: Safety Issues. In: Thomsen H., Webb J. (eds) Contrast Media. Medical ... ACR Manual on Contrast Media, version 8 (2012a) Contrast media in children, p 47-52 and p 79 http://www.acr.org/~/media/ACR/ ... Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Media Safety Committee guidelines. Eur ...
... an inlet port for connection with a container of a contrast agent or saline and for receiving the contrast agent or saline; and ... The general strategy in designing any contrast media relies upon exploiting the differences in contrast media distribution so ... An ideal contrast medium has innumerable criteria to meet before it is suitable for administration in the body. Since contrast ... With a new setup for each patient the unused contrast is discarded. This proves to be very costly as the contrast media is very ...
An exciting journal in the area of contrast agents and molecular imaging, covering all areas of imaging technologies with a ... Contrast Media articles will cover innovative work on all aspects of this field, such as the development of more sensitive ... Contrast Media & Molecular Imaging is included in many leading abstracting and indexing databases. For a complete list, click ... Contrast Media & Molecular Imaging is archived in Portico, which provides permanent archiving for electronic scholarly journals ...
An exciting journal in the area of contrast agents and molecular imaging, covering all areas of imaging technologies with a ... To receive news and publication updates for Contrast Media & Molecular Imaging, enter your email address in the box below. ... and reproduction in any medium, provided that the original work is properly cited. ...
Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media. ... Either allergic-type reactions or contrast-induced nephropathy may occur after administration of radiographic contrast media. ... Manual on contrast media. 6th ed. Reston (VA): The College; 2008. Available: www.acr.org/SecondaryMainMenuCategories/quality_ ... In patients who have had a previous allergic-type reaction to contrast media, premedication may be helpful. One example of a ...
... organic radiographic iodinated contrast media (ICM) have been among the most commonly prescribed drugs in the history of modern ... encoded search term (Contrast Medium Reactions) and Contrast Medium Reactions What to Read Next on Medscape. Related Conditions ... High-osmolality contrast media. High-osmolality contrast media consist of a tri-iodinated benzene ring with 2 organic side ... Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media. ...
Contrast-media induced nephropathy in patients undergoing coronary angiography.. Gomes VO1, Blaya P, Poli de Figueiredo CE, ... Contrast-medium induced nephropathy (CIN) in patients undergoing cardiac catheterization has an extremely variable incidence, ...
Global Contrast Media Injectors Market was valued at USD 630.1 million in 2013 and is estimated to reach a market worth USD ... Contrast media injectors are systems that inject contrast media into the body in order to enhance the quality of medical ... associated with the usage of contrast media or agents are also projected to negatively impact the application of contrast media ... Increasing Need for Contrast Scanning to Stimulate Demand for Contrast Media Injectors ...
The Report United States Contrast Media Injectors Market Outlook to 2022 provides information on pricing, market analysis, ... medical sciencechemicalsequipmentcontrast mediainjectorsmediamedia injectorscontrastcontrast media injectorscontrast media ... 3 Contrast Media Injectors Market, United States 6. 3.1 Contrast Media Injectors Market, United States, Revenue ($m), 2008-2015 ... "United States Contrast Media Injectors Market Outlook to 2022", provides key market data on the United States Contrast Media ...
Media Literacy Activity. Individual Exercise. Grades 9-12 In this exercise students will compare articles in order to hone ... Then compare and contrast the different articles considering, among other things (a) the assumptions they make (b) the tone ... their media literacy skills. This exercise can be done by using at least two articles on Worldpress.org. ...
The Hardcover of the Contrast Media in Magnetic Resonance Imaging by Val M. Runge at Barnes & Noble. FREE Shipping on $25.0 or ...
... using laser speckle contrast imaging. Computational imaging is used to reject sub-surface scattering and eliminates erroneous ...
This chapter from Transnational Leadership Development introduces leaders to the contrasts that exist between those raised in ... Contrasting Cultures. I-Centric and We-Centric. By Beth D., Ph. GELLER ... 2017 OReilly Media, Inc. All trademarks and registered trademarks appearing on oreilly.com are the property of their ... This chapter from Transnational Leadership Development introduces leaders to the contrasts that exist between those raised in ...
CMR 2005: 5.02: Nephrotoxicity of iodine contrast media, iso-osmolar to plasma, in comparison with gadolinium contrast media ... Current Awareness in Contrast Media and Molecular Imaging (pages 93-100). Version of Record online: 19 APR 2006 , DOI: 10.1002/ ... International Contrast Media Research Symposium-Program (pages 49-51). Version of Record online: 19 APR 2006 , DOI: 10.1002/ ... CMR 2005: 14.04: Oral manganese as contrast medium in detecting liver metastases with MR imaging at 1.5 and 3 T (pages 90-91). ...
ISRRTs Position Statment Supply and Administration of Contrast Agents - including Oral and Intravascular Administration to ... Usage of Contrast Media. ISRRTs Position Statment. Supply and Administration of Contrast Agents - including Oral and ... media/ACR/Documents/PDF/QualitySafety/Resources/Contrast%20Manual/2015_Contrast_Media.pdf ... The ISRRT Board promotes the scope of practice for the administration of oral and intravenous contrast agents by Radiographers ...
... conducted with no contrast media exceeded those conducted with contrast. Lorna Young explains why. ... CT contrast media suppliers, CT power injector manufacturers, and the IT integration of contrast media utilization reporting. ... IMV: CT contrast media reaches a crossroads as use dips. By Lorna Young, AuntMinnie.com contributing writer. April 2, 2020 -- ... without contrast, with contrast, and without and with contrast -- the latter is considered to be the most extensive exam. One ...
... approval of contrast agents for various indications, expanding indications of contrast agents, increasing number of contrast ... approval of contrast agents for various indications, expanding indications of contrast agents, increasing number of contrast ... Based on ionicity, the Iodine-based contrast agent is segmented into ionic and non-ionic. Non-Ionic Iodine-based contrast ... Based on ionicity, the Iodine-based contrast agent is segmented into ionic and non-ionic. Non-Ionic Iodine-based contrast ...
This article is published in Contrast Media and Molecular Imaging as part of the special issue on Photoacoustic Imaging, edited ... Previous article in issue: Emerging contrast agents for photoacoustic imaging Previous article in issue: Emerging contrast ... Because of this high scalability and its unique optical absorption contrast, PAT is capable of performing anatomical, ... Next article in issue: Advanced contrast nanoagents for photoacoustic molecular imaging, cytometry, blood test and photothermal ...
... contrast media include Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance ... MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent, Magnetically-Assisted ... Contrast Media: Substances used to allow enhanced visualization of tissues. .article_summary_container button.expand{ display: ... MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent. Xueming Wu1, Daniel ...
General principles of X-ray contrast media 10 13 Structure and properties of X-ray contrast media Barium sulfate 13 ... Contrast media in diagnostic imaging 8 Visualization of functions 8 • Morphology 9 • ... Nonionic contrast media 16 Osmolality and side effects caused by hypertonicity 18 Ionic contrast media 20 21 Contrast media for ... of X-ray contrast media 10 13 Structure and properties of X-ray contrast media Barium sulfate 13 Water-soluble contrast media ...
For use as a contrast medium [L1597].. DB09347. Acetrizoic acid. Acetrizoic acid indication was to be used as a contrast agent ... Iophendylate is used as a contrast agent to locate spinal tumors.. DB01249. Iodixanol. Iodixanol is a contrast agent during ... The use of contrast agents will provoke a contrast enhancement or opacification and it will improve the differentiation of ... Iopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial ...
... medium contrast fonts to offer for direct downloading · 1001 Fonts is your favorite site for free fonts since 2001 ... Hairline · Thin · Light · Regular · Medium · Bold · Heavy · Black · Fat. Width. Monospaced · Ultra Narrow · Extra Narrow · ... Handwritten, Medium Contrast Fonts. Fonts 1 - 10 of 129. *handwrittenx. *medium contrastx ...
... , provides key market data on the United Kingdom Contrast Media ... United Kingdom Contrast Agents Market Outlook to 2022. -Brazil Contrast Media Injectors Market Outlook to 2022. -Japan Contrast ... United States Contrast Media Injectors Market Outlook to 2022. -MediPoint: Contrast Media Injectors - Global Analysis and ... "United Kingdom Contrast Media Injectors Market Outlook to 2022", provides key market data on the United Kingdom Contrast Media ...
Gallstones from 100 patients were tested for buoyancy in four concentrations of contrast materials commonly used in the biliary ... Contrast Media / administration & dosage*. Diatrizoate Meglumine / administration & dosage. Humans. Specific Gravity. Chemical ... Gallstones from 100 patients were tested for buoyancy in four concentrations of contrast materials commonly used in the biliary ... substitution of the most dilute contrast material visible and the use of very low kilovoltage should help in one-fourth of ...
Though the frequency of side effects has fallen significantly since the introduction of nonionic, monomeric contrast agents,1 ... Low-osmolality contrast media (LOCM) are two to three times more osmolar than plasma, and iso-osmolar contrast media has the ... Iso-osmolar contrast media are increasingly used. The incidence of mild and moderate contrast reactions is higher for HOCM (6% ... The parent molecule from which the contrast agents are derived is benzene. Iodine is the element used in contrast media because ...
All classes of iodinated radiographic contrast media are vasoactive, with iso-osmolar dimers inducing the smallest changes in ... Routinely used iodinated contrast media have complex vasomotor effects on several arterial districts. ... Routinely used iodinated contrast media have complex vasomotor effects on several arterial districts. All classes of iodinated ... Contrast Media / adverse effects*, chemistry. Coronary Artery Disease / complications, physiopathology. Coronary Circulation / ...
... which are reflected in contrasting approaches to the media. Neither view is right or wrong. But the differing approaches help ... Chip Kelly, Herm Edwards and the media: Different styles, same goal, one fascinating contrast. ... The contrast, though, is fascinating. Why we need your support: Like so many other providers of local journalism across the ... More than half have been arranged through official channels, but many are simply the result of Edwards years in the media. He ...
PRNewswire/ -- The contrast media injectors market shall expand at a CAGR of 4.9% through 2030, but gains in 2020 will be ... Contrast Media Injectors Market- Competitive Landscape. The contrast media injectors market is characterized by several notable ... Contrast media injectors have been extensively utilized to introduce contrast agents in human tissues to enhance blood flow, ... Increasing demand for minimally invasive procedures is pushing manufacturers to fast track the production of contrast media ...
  • Market size and company share data for Contrast Media Injectors market segements - Angiographic Injectors, Computed Tomography (CT) Injectors and Magnetic Resonance Imaging (MRI) Injectors. (reportlinker.com)
  • Contrast Media Injectors are devices used to inject contrast media agents into the bloodstream of patients, to enable visualization of various pathologies through X-ray, computed tomography, magnetic resonance, or other medical imaging devices. (reportsandmarkets.com)
  • Two of the most common intravenous contrast media are iodinated contrast media for computed tomography (CT) and angiography, and gadolinium contrast media for magnetic resonance imaging (MRI). (biomedcentral.com)
  • Clinical risk associated with contrast angiography in metformin treated patients: a clinical review. (foreverframe.net)
  • In twenty-six patients referred for angiography, clearance of contrast medium was determined with x-ray fluorescence analysis after multiple injections of contrast medium. (elsevier.com)
  • the correlation between contrast medium clearance calculated without correction for the different injection times, and 51 Cr-EDTA clearance was the same (r=0.946), due to short angiography time and rather low clearance values in our patients. (elsevier.com)
  • VIENNA--( BUSINESS WIRE )--Growing its range of magnetic resonance imaging (MRI) contrast media options available to patients and radiologists, GE Healthcare today announced the launch of Clariscan™ (gadoteric acid) at the European Congress of Radiology (ECR) 2017 meeting. (businesswire.com)
  • It is the latest in a line of products and services provided by GE Healthcare to the radiology community, which include a wide range of contrast media as well as a portfolio of systems and products across MRI, X-ray/CT and ultrasound modalities. (businesswire.com)
  • Contrast media · › Contrast media · › Prostate MRI · › NSF · › NSF Endometrial Cancer MRI Staging: Updated Guidelines of the European European Society of Urogenital Radiology (ESUR) Guidelines: MR Imaging of Leiomyomas. (epsscentral.info)
  • Iodinated and gadolinium-based contrast media are used on a daily basis in most radiology practices. (foreverframe.net)
  • Contrast Media Safety Committee Of The European Society Of Urogenital Radiology. (foreverframe.net)
  • The Radiologist may suggest you have another radiology examination that doesn't require contrast media, or suggest you take something (eg antihistamine) prior to your appointment. (mokoiaradiology.co.nz)
  • The clinical pattern of diagnostic radiology has been made possible by progresss by diagnostic equipment and fact-finding techniques, as in the contrast media that permit visual image of the inside informations in the internal construction or variety meats that would non otherwise be incontrovertible. (niagarafallshypnosiscenter.com)
  • Growth in the ultrasound segment can largely be attributed to several advantages offered by ultrasound contrast agents over other contrast agents and the rising number of approvals for ultrasound contrast agents in the US, Europe, and Japan. (marketsandmarkets.com)
  • The same reactions are seen after iodine- and gadolinium-based contrast agents and after ultrasound contrast agents. (epsscentral.info)
  • All contrast media are referred to by generic Key words: Contrast media-Adverse reactions-Safety names, except when the generic name is confusing issues-Guidelines (ultrasound contrast agents). (foreverframe.net)
  • The major factors driving the growth of the contrast media/contrast agents market include increasing number of research and funding activities for research of contrast agents and their applications. (marketsandmarkets.com)
  • On the basis of type, the contrast media/contrast agents market is segmented into iodinated contrast media, gadolinium-based contrast media, barium-based contrast media, and microbubble contrast media. (marketsandmarkets.com)
  • North America, Europe, Asia-Pacific, and Rest of the World (RoW) are the regions considered for a geographic analysis of the global contrast media/contrast agents market. (marketsandmarkets.com)
  • North American contrast media/contrast agents market is expected to account for the largest share of the global contrast media/contrast agents market. (marketsandmarkets.com)
  • However, the Asia Pacific contrast media/contrast agents market is expected to grow at the highest CAGR in the forecast period. (marketsandmarkets.com)
  • The prominent players in the global contrast media/contrast agents market include GE Healthcare (US), Bracco Imaging S.p.A. (Bracco) (Italy), Bayer HealthCare (Bayer) (Germany), and Guerbet Group (Guerbet) (France). (marketsandmarkets.com)
  • Don t miss out on business opportunities in Contrast Media/Contrast Agents Market. (marketsandmarkets.com)
  • Emmanuel Ligner, General Manager of Core Imaging for GE Healthcare Life Sciences, said: "Gadolinium-based agents are known to be a gold-standard detection tool in MR imaging, offering improved contrast between normal and pathological tissue to enable rapid detection of abnormalities. (businesswire.com)
  • Do not administer gadolinium-based contrast agents. (epsscentral.info)
  • The incidence is highest after iodine-based contrast agents and lowest after ultrasound agents. (epsscentral.info)
  • When there is a very strong indication for enhanced MR, the smallest possible dose of one of the most stable gadolinium contrast agents see Contrast agents: Gadolinium- containing contrast media for radiographic examinations: Contrast induced nephropathy CIN is a condition in which a decrease in renal function occurs within 3 days of the intravascular administration of a CM in the absence of an alternative aetiology. (epsscentral.info)
  • Breast feeding should be avoided for 24 hours after contrast medium if high risk agents are used. (epsscentral.info)
  • These revised guidelines are necessary because of the ever-changing literature about both iodinated contrast media and gadolinium-based contrast agents (GBCAs). (foreverframe.net)
  • Iodinated contrast media guideline pdf guidelines on the use of in patients with kidney disease 2012: digest version semantic scholar safe part 1 name policy: intravenous agents policy number: 3364 135 131 responsible agent: direct. (foreverframe.net)
  • though there are several but most common contrast agents work on X-ray attenuation and magnetic resonance signal improvement. (whatech.com)
  • On the other manus another positive contrast media is iodine based and they are categorized as ionic H2O soluble, non-ionic H2O soluble, greasy agents and agents excreted in the gall. (niagarafallshypnosiscenter.com)
  • Contrast agents with more protein binding capacity, illustration meglumine, ioglycomate are besides excreted in the bilious system. (niagarafallshypnosiscenter.com)
  • Current recommendations and guidelines for administration of radiologic contrast media are reviewed, as well as management of adverse reactions. (foreverframe.net)
  • Adverse reactions to iodinated and gadolinium contrast media are an important clinical issue. (biomedcentral.com)
  • Of these, 152 were for prior acute adverse reactions to contrast media, 85 were for a history of bronchial asthma, and 15 were for other reasons. (biomedcentral.com)
  • This study by no means proves the efficacy of premedication, but provides some support for following a premedication protocol to improve safety of contrast-enhanced examinations when prior adverse reactions are mild, or when there is a history of asthma. (biomedcentral.com)
  • These contrast media are relatively safe, but adverse reactions to contrast media are still an important clinical issue. (biomedcentral.com)
  • In our institution, as a general rule, patients with a history of severe or moderate adverse reactions to contrast do not undergo contrast-enhanced examinations. (biomedcentral.com)
  • Patients' demographic data, history of adverse reactions (type and severity) to contrast media, history of asthma, history of other allergic reactions, reason for adopting premedication protocol, contrast media used, amount of contrast media, and type, severity, treatment and outcomes of BTR (if any) were collected. (biomedcentral.com)
  • However, the microbubble contrast media segment is expected to grow at the highest CAGR during the forecast period. (marketsandmarkets.com)
  • Patients undergoing therapy with radioactive iodine should not have received iodine-based contrast media for at least two months before treatment. (epsscentral.info)
  • In 2017, X-ray/CT procedures are expected to command the largest share of the global contrast media market. (marketsandmarkets.com)
  • Particular attention is drawn to the risks of contrast induced nephropathy (CIN), and the reduction of those risks wherever possible. (foreverframe.net)
  • abstract = "The effects of intravenous contrast media (CM) on renal excretory function and subcellular morphology are examined in this animal investigation. (elsevier.com)
  • The report " Global Contrast Media Market - Size, Outlook, Trends, and Forecasts (2018 - 2024)" the Global Contrast Media Market expected to reach USD X Million by the year 2024, at a CAGR of 5.3% during forecast period. (whatech.com)
  • The Asia Pacific Contrast Media market is expected to expand at a promising CAGR during the forecast period. (sciencenewspress.com)
  • The model discusses in detail the impact of COVID-19 on Contrast Media Injectors market for the year 2020 and beyond. (reportsnreports.com)
  • and in a small number of people, certain side effects can occur following an injection of contrast agent. (mokoiaradiology.co.nz)
  • A formula for correction of the injected amount, which takes into consideration the different times of contrast medium injections, approximating the total injected amount into one injection, was used. (elsevier.com)
  • the results showed a good correlation between the clearance of contrast medium after multiple injections and the 51 Cr-EDTA clearance after a single injection (r=0.945). (elsevier.com)
  • It is concluded that total plasma clearance of contrast medium can easily be estimated after multiple injections. (elsevier.com)
  • Contrast medium extravasation injury: Gadolinium-based contrast medium Hemodialysis to remove the contrast medium is unnecessary for iodine-based contrast medium, but for gadolinium- based contrast medium. (epsscentral.info)
  • Contrast medium extravasation injury: guidelines for prevention and management. (foreverframe.net)
  • ORIGINAL RESEARCH STATEMENTS AND GUIDELINES Introduction and Background Intravenous iodinated contrast media are commonly used with CT to evaluate disease and to determine treatment response. (foreverframe.net)
  • Fischer, Harry W. / Effects of contrast media on renal function and subcellular morphology in the dog . (elsevier.com)
  • However, high cost associated with the devices and lack of skilled professional to operate the system are a few factors that may hamper the growth in the Contrast Media industry. (sciencenewspress.com)
  • Objectives: Because the distribution volume and mechanism of extracellular and intravascular MR contrast media differ considerably, the enhancement pattern of chronic myocardial infarction with extracellular or intravascular media might also be different. (canada.ca)
  • This study aims to investigate the differences in MR enhancement patterns of chronic myocardial infarction between extracellular and intravascular contrast media. (canada.ca)
  • Materials and Methods: Twenty pigs with myocardial infarction underwent cine MRI, first pass perfusion MRI and delayed enhancement MRI with extracellular or intravascular media at four weeks after coronary occlusion. (canada.ca)
  • At the following delayed enhancement phase, extracellular media-enhanced signal intensity was significantly higher in chronic infarction than in normal myocardium. (canada.ca)
  • nonetheless, intravascular media didn't provide delayed enhancement. (canada.ca)
  • Clariscan is a gadolinium-based contrast agent (GBCA) designed to support effective visualisation of abnormalities in the brain, spine and associated tissues, and will be provided alongside GE Healthcare's comprehensive support services and solutions to healthcare practitioners worldwide. (businesswire.com)
  • We are therefore pleased to add Clariscan to the family of GE contrast media and imaging products alongside our existing linear agent for MRI, Omniscan, which has been used in routine diagnostic practice for over 25 years with over 80 million administrations. (businesswire.com)
  • The risk of an acute reaction to a gadolinium-based contrast agent is lower than the risk with an iodine-based contrast agent, but severe reactions to gadolinium-based contrast media may occur. (epsscentral.info)
  • This contrast agent causes no complication in the vast majority of people who have it. (mokoiaradiology.co.nz)
  • The medical contrast medium is additionally named as a contrast agent. (whatech.com)
  • The contrast agent may be a substance used to increase the contrast of structures or fluids at intervals the body in medical imaging. (whatech.com)
  • In positive contrast media there are besides two types of contrast agent which are iodine based and Ba based. (niagarafallshypnosiscenter.com)
  • GlobalData's new report, "Italy Contrast Media Injectors Market Outlook to 2022", provides key market data on the Italy Contrast Media Injectors market. (reportlinker.com)
  • Global corporate-level profiles of key companies operating within the Italy Contrast Media Injectors market. (reportlinker.com)
  • Contrast Media Injectors (Diagnostic Imaging) - Global Market Analysis and Forecast Model (COVID-19 market impact) is built to visualize quantitative market trends within Diagnostic Imaging therapeutic area. (reportsnreports.com)
  • The market for contrast media injectors is driven by sales of diagnostic imaging systems such as MRI and CT scanners, which have been experiencing growth due to aging global populations and the rising prevalence of chronic diseases. (reportsnreports.com)
  • The market for contrast media injectors is experiencing stable growth globally and high growth in emerging economies like China and India whose health sectors are booming. (reportsnreports.com)
  • Annualized total Contrast Media Injectors market revenue by segment and market outlooks from 2015-2030. (reportsnreports.com)
  • SWOT analysis for Contrast Media Injectors market. (reportsnreports.com)
  • Competitive dynamics insights and trends provided for Contrast Media Injectors market. (reportsnreports.com)
  • Develop business strategies by understanding the trends shaping and driving the Contrast Media Injectors market. (reportsandmarkets.com)
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the Contrast Media Injectors market in the future. (reportsandmarkets.com)
  • The Global contrast Media Market share would possibly develop to X Million at a CAGR of 5.3% from 2018-2024. (whatech.com)
  • The Contrast Media Market to gain from rapid technological advancements taking place in the market. (sciencenewspress.com)
  • As per the report in 2019 the industry market was valued at US$ Contrast Media. (sciencenewspress.com)
  • Owing to increasing competition frequent innovations are taking place in the Contrast Media market. (sciencenewspress.com)
  • Rapid adoption of digitalization among practitioners and patients is likely to fuel the demand in the Contrast Media market. (sciencenewspress.com)
  • Contrast media injectors can be categorized as manual, automatic, syringeless, dual or single headed. (reportsnreports.com)
  • As part of a number of examinations, you may need to have an injection of Radiographic Contrast Medium. (mokoiaradiology.co.nz)
  • All iodinated and gadolinium contrast-enhanced radiologic examinations between August 2011 and February 2013 for which the premedication protocol was applied in our institution were assessed for BTRs. (biomedcentral.com)
  • Those with a history of mild reactions or a history of bronchial asthma will undergo contrast-enhanced examinations only when they have received oral premedication. (biomedcentral.com)
  • All patients who underwent contrast-enhanced examinations using iodinated and gadolinium contrast media between August 2011 and February 2013 while following our institution's premedication protocol were evaluated by retrospective chart review. (biomedcentral.com)