Contrast Media: Substances used to allow enhanced visualization of tissues.Triiodobenzoic Acids: Triiodo-substituted derivatives of BENZOIC ACID.Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.Iopamidol: A non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures.Ioxaglic Acid: A low-osmolar, ionic contrast medium used in various radiographic procedures.Diatrizoate: A commonly used x-ray contrast medium. As DIATRIZOATE MEGLUMINE and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.Diatrizoate Meglumine: A versatile contrast medium used for DIAGNOSTIC X-RAY RADIOLOGY.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Iodine Compounds: Inorganic compounds that contain iodine as an integral part of the molecule.Iothalamate Meglumine: A radiopaque medium used for urography, angiography, venography, and myelography. It is highly viscous and binds to plasma proteins.Extravasation of Diagnostic and Therapeutic Materials: The escape of diagnostic or therapeutic material from the vessel into which it is introduced into the surrounding tissue or body cavity.Urography: Radiography of any part of the urinary tract.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Gadolinium DTPA: A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)Gadolinium: Gadolinium. An element of the rare earth family of metals. It has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.Hysterosalpingography: Radiography of the uterus and fallopian tubes after the injection of a contrast medium.Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.Iodized Oil: A preparation of oil that contains covalently bound IODINE. It is commonly used as a RADIOCONTRAST AGENT and as a suspension medium for CHEMOTHERAPEUTIC AGENTS.Angiography: Radiography of blood vessels after injection of a contrast medium.Osmolar Concentration: The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.Angiocardiography: Radiography of the heart and great vessels after injection of a contrast medium.Iodopyridones: Iodinated pyridine derivatives that are often used as contrast media.Iothalamic Acid: A contrast medium in diagnostic radiology with properties similar to those of diatrizoic acid. It is used primarily as its sodium and meglumine (IOTHALAMATE MEGLUMINE) salts.Fallopian Tube Patency Tests: Methods for assessing the patency of the fallopian tubes.Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Radiography, Interventional: Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.Iodobenzoates: Benzoic acid esters or salts substituted with one or more iodine atoms.Injections, Intra-Arterial: Delivery of drugs into an artery.Coronary Angiography: Radiography of the vascular system of the heart muscle after injection of a contrast medium.CreatinineThorium Dioxide: Thorium oxide (ThO2). A radiographic contrast agent that was used in the early 1930s through about 1954. High rates of mortality have been linked to its use and it has been shown to cause liver cancer.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Nephrogenic Fibrosing Dermopathy: A chronic, acquired, idiopathic, progressive eruption of the skin that occurs in the context of RENAL FAILURE. It is sometimes accompanied by systemic fibrosis. The pathogenesis seems to be multifactorial, with postulated involvement of circulating fibrocytes. There is a strong association between this disorder and the use of gadolinium-based contrast agents.Angiography, Digital Subtraction: A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.Mass Media: Instruments or technological means of communication that reach large numbers of people with a common message: press, radio, television, etc.Iophendylate: An inert iodine-containing agent which is opaque to X-RAYS. It is used mainly for BRAIN and SPINAL CORD visualization.Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.Cerebral Angiography: Radiography of the vascular system of the brain after injection of a contrast medium.Sodium Bicarbonate: A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.Organometallic Compounds: A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)Tungsten Compounds: Inorganic compounds that contain tungsten as an integral part of the molecule.Multidetector Computed Tomography: Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.Subacute Care: Medical and skilled nursing services provided to patients who are not in an acute phase of an illness but who require a level of care higher than that provided in a long-term care setting. (JCAHO, Lexikon, 1994)Image Enhancement: Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.Endolymphatic Hydrops: An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.Acetylcysteine: The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.Culture Media, Conditioned: Culture media containing biologically active components obtained from previously cultured cells or tissues that have released into the media substances affecting certain cell functions (e.g., growth, lysis).Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Myelography: X-ray visualization of the spinal cord following injection of contrast medium into the spinal arachnoid space.Radiographic Image Enhancement: Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Cholecystography: Radiography of the gallbladder after ingestion of a contrast medium.Diverticulosis, Colonic: A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Fluoroscopy: Production of an image when x-rays strike a fluorescent screen.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Imaging, Three-Dimensional: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.Embolization, Therapeutic: A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.Cholangiography: An imaging test of the BILIARY TRACT in which a contrast dye (RADIOPAQUE MEDIA) is injected into the BILE DUCT and x-ray pictures are taken.Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Epidural Space: Space between the dura mater and the walls of the vertebral canal.Ultrasonography: The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.Tomography, Spiral Computed: Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.Maleic Anhydrides: Used in copolymerization reactions, in the Diels-Alder(diene)synthesis, in the preparation of resins, pharmaceuticals and agricultural chemicals. It is a powerful irritant and causes burns.Lymphography: Radiographic study of the lymphatic system following injection of dye or contrast medium.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Fluid Therapy: Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS.Intervertebral Disc Displacement: An INTERVERTEBRAL DISC in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.Angioplasty, Balloon, Coronary: Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.Economics, Hospital: Economic aspects related to the management and operation of a hospital.Hemangioma, Cavernous: A vascular anomaly that is a collection of tortuous BLOOD VESSELS and connective tissue. This tumor-like mass with the large vascular space is filled with blood and usually appears as a strawberry-like lesion in the subcutaneous areas of the face, extremities, or other regions of the body including the central nervous system.Cineangiography: Motion pictures of the passage of contrast medium through blood vessels.Microbubbles: Small encapsulated gas bubbles (diameters of micrometers) that can be used as CONTRAST MEDIA, and in other diagnostic and therapeutic applications. Upon exposure to sufficiently intense ultrasound, microbubbles will cavitate, rupture, disappear, release gas content. Such characteristics of the microbubbles can be used to enhance diagnostic tests, dissolve blood clots, and deliver drugs or genes for therapy.Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.Ultrasonography, Doppler, Color: Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.Heterocyclic Compounds: Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)Fallopian Tubes: A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.Arachnoiditis: Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)Meniere Disease: A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Sulfur Hexafluoride: Sulfur hexafluoride. An inert gas used mainly as a test gas in respiratory physiology. Other uses include its injection in vitreoretinal surgery to restore the vitreous chamber and as a tracer in monitoring the dispersion and deposition of air pollutants.Meglumine: 1-Deoxy-1-(methylamino)-D-glucitol. A derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. Often used in conjunction with iodinated organic compounds as contrast medium.Cerebral Ventriculography: Radiography of the ventricular system of the brain after injection of air or other contrast medium directly into the cerebral ventricles. It is used also for x-ray computed tomography of the cerebral ventricles.Radiographic Image Interpretation, Computer-Assisted: Computer systems or networks designed to provide radiographic interpretive information.Blood Volume Determination: Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight.Coronary Thrombosis: Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Phlebography: Radiographic visualization or recording of a vein after the injection of contrast medium.Chylothorax: The presence of chyle in the thoracic cavity. (Dorland, 27th ed)Glomerular Filtration Rate: The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance.Sodium Chloride: A ubiquitous sodium salt that is commonly used to season food.Radiation Dosage: The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).Ions: An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.Injections: Introduction of substances into the body using a needle and syringe.Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Phantoms, Imaging: Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)Scintillation Counting: Detection and counting of scintillations produced in a fluorescent material by ionizing radiation.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.Social Media: Platforms that provide the ability and tools to create and publish information accessed via the INTERNET. Generally these platforms have three characteristics with content user generated, high degree of interaction between creator and viewer, and easily integrated with other sites.Tissue Adhesions: Pathological processes consisting of the union of the opposing surfaces of a wound.Lipoma: A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.Renal Artery: A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.Intracranial Arteriovenous Malformations: Congenital vascular anomalies in the brain characterized by direct communication between an artery and a vein without passing through the CAPILLARIES. The locations and size of the shunts determine the symptoms including HEADACHES; SEIZURES; STROKE; INTRACRANIAL HEMORRHAGES; mass effect; and vascular steal effect.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Evaluation Studies as Topic: Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.Hemodiafiltration: The combination of hemodialysis and hemofiltration either simultaneously or sequentially. Convective transport (hemofiltration) may be better for removal of larger molecular weight substances and diffusive transport (hemodialysis) for smaller molecular weight solutes.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Culture Media, Serum-Free: CULTURE MEDIA free of serum proteins but including the minimal essential substances required for cell growth. This type of medium avoids the presence of extraneous substances that may affect cell proliferation or unwanted activation of cells.Arthrography: Roentgenography of a joint, usually after injection of either positive or negative contrast medium.Agar: A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.Artifacts: Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.Iatrogenic Disease: Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.Liver Neoplasms: Tumors or cancer of the LIVER.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Communications Media: The means of interchanging or transmitting and receiving information. Historically the media were written: books, journals, newspapers, and other publications; in the modern age the media include, in addition, radio, television, computers, and information networks.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Aortography: Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.Infertility, Female: Diminished or absent ability of a female to achieve conception.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Diagnostic Imaging: Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.Kidney Function Tests: Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.Acute Disease: Disease having a short and relatively severe course.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Bismuth: A metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.Dextrans: A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.Coronary Vessels: The veins and arteries of the HEART.Spinal DiseasesSalicylates: The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.Ultrasonography, Interventional: The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.Magnetics: The study of MAGNETIC PHENOMENA.Renal Circulation: The circulation of the BLOOD through the vessels of the KIDNEY.Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Equipment Design: Methods of creating machines and devices.Blood Urea Nitrogen: The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)Heart Septal Defects, Atrial: Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.Bacteriological Techniques: Techniques used in studying bacteria.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.PolysaccharidesEndoscopy: Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.Recurrence: The return of a sign, symptom, or disease after a remission.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Free Radical Scavengers: Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.Ultrasonography, Doppler, Duplex: Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.Kidney Cortex: The outer zone of the KIDNEY, beneath the capsule, consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Histamine Release: The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Iodine Radioisotopes: Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Regional patterns of myocardial sympathetic denervation in dilated cardiomyopathy: an analysis using carbon-11 hydroxyephedrine and positron emission tomography. (1/6913)

OBJECTIVE: To assess presynaptic function of cardiac autonomic innervation in patients with advanced congestive heart failure using positron emission tomography (PET) and the recently developed radiolabelled catecholamine analogue carbon-11 hydroxyephedrine (HED) as a marker for neuronal catecholamine uptake function. DESIGN AND PATIENTS: 29 patients suffering from dilated cardiomyopathy with moderate to severe heart failure were compared with eight healthy controls. Perfusion scan was followed by HED dynamic PET imaging of cardiac sympathetic innervation. The scintigraphic results were compared with markers of disease severity and the degree of sympathetic dysfunction assessed by means of heart rate variability. RESULTS: In contrast to nearly normal perfusions, mean (SD) HED retention in dilated cardiomyopathy patients was abnormal in 64 (32)% of the left ventricle. Absolute myocardial HED retention was 10.7 (1.0)%/min in controls v 6.2 (1.6)%/min in dilated cardiomyopathy patients (p < 0.001). Moreover, significant regional reduction of HED retention was demonstrated in apical and inferoapical segments. HED retention was significantly correlated with New York Heart Association functional class (r = -0.55, p = 0. 002) and ejection fraction (r = 0.63, p < 0.001), but not, however, with plasma noradrenaline concentrations as well as parameters of heart rate variability. CONCLUSIONS: In this study, using PET in combination with HED in patients with dilated cardiomyopathy, not only global reduction but also regional abnormalities of cardiac sympathetic tracer uptake were demonstrated. The degree of abnormality was positively correlated to markers of severity of heart failure. The pathogenetic mechanisms leading to the regional differences of neuronal damage as well as the prognostic significance of these findings remain to be defined.  (+info)

3D angiography. Clinical interest. First applications in interventional neuroradiology. (2/6913)

3D angiography is a true technical revolution that allows improvement in the quality and safety of diagnostic and endovascular treatment procedures. 3D angiography images are obtained by reconstruction of a rotational angiography acquisition done on a C-arm (GE Medical Systems) spinning at 40 degrees per second. The carotid or vertebral selective injection of a total of 15 ml of non-ionic contrast media at 3 ml/sec over 5 seconds allows the selection of the "arterial phase". Four hundred sixty 3D angiographic studies were performed from December 1996 to September 1998 on 260 patients and have been analyzed in MIP (Maximum Intensity Projection) and SSD (Shaded Surface Display) views. The exploration of intracranial aneurysms is simplified and only requires, for each vascular axis, a biplane PA and Lateral run followed by a single rotational angiography run. The 3D angiography image is available on the workstation's screen (Advantage Workstation 3.1, GE Medical Systems) in less than 10 minutes after the acquisition of the rotational run. It therefore allows one to analyze, during the intervention, the aneurysm's angioarchitecture, in particular the neck, and select the best therapeutic technique. When endovascular treatment is the best indication, 3D angiography allows one to define the optimal angle of view and accurately select the microcoils dimensions. 3D angiography replaces the multiple oblique views that used to be required to analyze the complex aneurysms and therefore allows a reduction of the total contrast medium quantity, the patient X-ray dose and the length of the intervention time which is a safety factor. Also, in particular for complex cases, it brings additional elements complementing the results of standard 2D DSA and rotational angiograms. In the cervical vascular pathology, 3D angiography allows for a better assessment of the stenosis level and of dissection lesions. Our current research activities focus on the matching without stereotactic frame between 3D X-ray angiography and volumetric MR acquisition, which should allow us to improve the treatment of intracerebral arterio-venous malformations (AVMs).  (+info)

3D MRI of the membranous labyrinth. An age related comparison of MR findings in patients with labyrinthine fibrosis and in persons without inner ear symptoms. (3/6913)

PURPOSE: We compared MRI of the membranous labyrinth in patients with chronic non-neoplastic inner ear disease and MR signs of labyrinthine fibrosis and controls depending on their age, in order to establish whether there were any MR differences regarding patient age groups, control age groups and between the patients and controls themselves. MATERIALS AND METHODS: Clinical ENT examinations as well as a T2* weighted 3D CISS (Constructive Interference in Steady State) sequence with a slice thickness of 0.7 mm were performed. Our collective was subdivided as follows: 0-19 years (10 controls, 3 patients with chronic non-neoplastic inner ear disease), 20-49 years (55 controls, 8 patients), 50 years and older (40 controls, 22 patients). Detectability of labyrinthine structures (e.g. cochlea, vestibule, semicircular canals) and filling defects were evaluated. RESULTS: In the 3 age-groups of the control collective no significant differences were observed in the membranous labyrinth. However differences concerning labyrinthine detectability emerged between controls and patients in both the 20-49 years and 50 years and older age groups. In the patient collective the 3 age groups showed no significant discrepancy in the mean number of lesions. CONCLUSION: Filling defects of the membranous labyrinth on 3D CISS MR images are pathological even in older persons. We would therefore recommend high resolution T2* weighted MRI in the case of suspected labyrinthine fibrosis.  (+info)

Angiographical extravasation of contrast medium in hemorrhagic infarction. Case report. (4/6913)

Leakage of the contrast medium was noted on angiograms of a patient whose autopsied brain disclosed typical pathological findings of hemorrhagic infarction. The case was a 63-year old woman with mitral valve failure, who suddenly had loss of consciousness and right-sided hemiplegia. The left carotid angiography performed six hours after onset demonstrated middle cerebral arterial axis occlusion, and the second angiography performed three days after onset displayed recanalization of the initially occluded artery as well as extravasation of the contrast medium. Fourteen days after onset the patient died and an autopsy was performed. The brain demonstrated perivascular punctate hemorrhages in the area supplied by the middle cerebral artery, and neither hematoma nor microaneurysm was disclosed pathologically. A short discussion is given on the possible relationship between recanalization and hemorrhagic infarction. The clinical assessment of hemorrhagic infarction has not been established successfully.  (+info)

Comparative cytotoxicity of ionic and non-ionic radiocontrast agents on MDCK cell monolayers in vitro. (5/6913)

BACKGROUND: Intravascular radiocontrast agents may cause acute renal failure, particularly in patients with pre-existing renal insufficiency. Direct cytotoxic effects of radiocontrast agents on renal tubular cells may contribute to the pathogenesis of radiocontrast-induced nephropathy. METHODS: We analysed the cytotoxicity of the ionic radiocontrast agents diatrizoate (monomeric) and ioxaglate (dimeric), as well as of the non-ionic radiocontrast agents iohexol (monomeric) and iodixanol (dimeric) on the renal epithelial Madin Darby Canine Kidney (MDCK) cell line grown on permeable supports. The toxicity assays assessed cell viability, transmonolayer resistance and inulin permeability between the apical and basal cell culture compartment. In addition, the distribution of the tight-junction-associated membrane proteins ZO-1 and occludin was analysed using immunofluorescence microscopy. RESULTS: In all assays the high osmolal ionic compound diatrizoate had significant cytotoxic effects that included the partial redistribution of the tight-junction-associated membrane proteins into a cytoplasmic compartment. To a lesser extent this redistribution also occurred with the dimeric ionic compound ioxaglate, but not with the non-ionic radiocontrast agents. With regards to cell viability, transmonolayer resistance and inulin permeability the radiocontrast agents with reduced osmolality were significantly less toxic than diatrizoate, independent of their ionic strength. CONCLUSIONS: Physicochemical factors contribute to the cytotoxicity of radiocontrast agents in vitro. The redistribution of tight-junction-associated membrane proteins by the ionic radiocontrast agents corresponds with the loss of the barrier function of the epithelial cell monolayer, which is a major pathophysiological mechanism in acute renal failure. The radiocontrast agents with reduced osmolality are less cytotoxic than diatrizoate, independent of their ionicity. Hyperosmolality appears to be a more important determinant of the cytotoxicity of diatrizoate than ionic strength.  (+info)

Enhancement of endocytosis due to aminophospholipid transport across the plasma membrane of living cells. (6/6913)

Formation of intracellular vesicles is initiated by membrane budding. Here we test the hypothesis that the plasma membrane surface area asymmetry could be a driving force for vesicle formation during endocytosis. The inner layer phospholipid number was therefore increased by adding exogenous aminophospholipids to living cells, which were then translocated from the outer to the inner layer of the membrane by the ubiquitous flippase. Addition of either phosphatidylserine or phosphatidylethanolamine led to an enhancement of endocytosis, showing that the observed acceleration does not depend on the lipid polar head group. Conversely, a closely related aminophospholipid that is not recognized by the flippase, lyso-alpha-phosphatidylserine, inhibited endocytosis, and similar results were obtained with a cholesterol derivative that also remains in the plasma membrane outer layer. Thus an increase of lipid concentration in the inner layer enhanced internalization, whereas an increase of the lipid concentration in the outer layer inhibited internalization. These experiments suggest that transient asymmetries in lipid concentration might contribute to the formation of endocytic vesicles.  (+info)

Thorotrast associated nodular regenerative hyperplasia of the liver. (7/6913)

A case of nodular regenerative hyperplasia (NRH) of the liver is described in association with exposure to the radiographic contrast medium Thorotrast. This is the first case in which the pathological findings have been fully documented. It is suggested that NRH may have developed through Thorotrast induced damage to portal vein radicles.  (+info)

Intravaginal saline as a contrast agent for cervical sonography in the obstetric patient. (8/6913)

OBJECTIVE: To determine whether intravaginal saline alters visualization of the cervix during endovaginal sonographic examinations. DESIGN: A prospective trial with comparison of sonographic measurements of cervical length prior to and after administration of an intravaginal contrast agent. SUBJECTS: Patients with an indication for endovaginal ultrasonographic assessment of the cervix were considered as candidates for the study. METHODS: After assessment of cervical dimensions and contour of the internal cervical os, 10 ml of normal saline was placed intravaginally via a needleless syringe. Pre- and post-contrast sonographic examinations of the cervix were compared. RESULTS: Twenty-six patients were enrolled. No differences were observed in the identification of funnelling (37% in each group, p = 1.0) or the quantification of cervical length for the entire cohort (p = 0.95). However, in a subset of patients in whom the external os was not satisfactorily visualized (23%), intravaginal contrast resulted in a mean difference in cervical length pre- and post-saline infusion of 6.4 mm compared to 1.4 mm in patients in whom the external os could be easily identified (p < 0.001). No patient expressed undue discomfort related to the administration of contrast. CONCLUSION: Intravaginal saline assists in visualization of the cervix during endovaginal sonography for selected patients in whom precise identification of the external os is difficult.  (+info)

*Medication

contrast media For euthanasia[edit]. See also: Barbiturate § Other non-therapeutical uses ...

*Medication

contrast media For euthanasia[edit]. See also: Barbiturate § Other non-therapeutical uses ...

*Medication

contrast media For euthanasia[edit]. See also: Barbiturate. A euthanaticum is used for euthanasia and physician-assisted ...

*Category:Medical imaging

Media in category "Medical imaging". This category contains only the following file. ... Contrast-enhanced. *3D ultrasound. *Endoscopic ultrasound. *Emergency ultrasound *FAST. *Pre-hospital ultrasound ...

*Upper gastrointestinal series

In this case the gas is referred to as the negative contrast medium. Traditionally the images produced with barium contrast are ... Barium meal examination showing the stomach and duodenum in double contrast technique with CO2 as negative contrast medium ... A contrast medium, usually a radiocontrast agent such as barium sulfate mixed with water, is ingested or instilled into the ... Barium sulfate as a contrast medium in medical practice was introduced largely as a result of the works of Krause a director of ...

*Renal cortical necrosis

Drug-induced toxicity (e.g. NSAIDs, Contrast Media, Quinine,[13] or ATRA[14]) ... Alternatively, it is diagnosed clinically, or at autopsy, with some authors suggesting diagnosis by contrast enhanced CT.[17] ...

*Gadobenic acid

2009). "Contrast Media". Martindale: The Complete Drug Reference (36th ed.). London: Pharmaceutical Press. p. 1478. ISBN 978-0- ... it is used as a gadolinium-based MRI contrast medium. BOPTA is a derivative of DTPA in which one terminal carboxyl group, -C(O) ... "Novel contrast agents for magnetic resonance imaging. Synthesis and characterization of the ligand BOPTA and its Ln(III) ... providing a mechanism for MRI contrast enhancement. 139La NMR studies on the diamagnetic La-BOPTA2− complex suggest that the Gd ...

*Cholecystography

"Cholegraphic contrast medium". Medcyclopaedia. GE. Duncan, C; Riall, T (2012). "Evidence-Based Current Surgical Practice: ... A radiopaque cholegraphic (contrast) agent, usually iopanoic acid (Telepaque) or its sodium or calcium salt, is orally ... This excreted material will collect in the gallbladder, where reabsorption of water concentrates the excreted contrast. Since ...

*Hyperpolarized carbon-13 MRI

Contrast Media & Molecular Imaging. 8 (1): 57-62. doi:10.1002/cmmi.1494. Yen, Yi-Fen; Le Roux, Patrick; Mayer, Dirk; King, ... In contrast with conventional MRI, hyperpolarized experiments are inherently dynamic as images must be acquired as the injected ... In contrast with other metabolic imaging methods such as positron emission tomography, hyperpolarized carbon-13 MRI provides ...

*Bernard Fantus

"X‐Ray Contrast Media*." The Journal of the American Pharmaceutical Association (1912) The Journal of the American ... Ray Contrast Media* Fantus, Bernard. Collection, [Box 1, Folders 13, 14, 15, 16], Special Collections Research Center, ...

*Diatrizoate

Thomsen, Henrik; Muller, Robert N.; Mattrey, Robert F. (2012). Trends in Contrast Media. Springer Science & Business Media. p. ... It is given intravenously to enhance contrast in computed tomography, to image the kidneys and related structures, and to image ... Diatrizoate, also known as amidotrizoate, is a contrast agent used during X-rays. This includes when visualizing veins, the ... Diatrizoate is considered a high-osmolality contrast agent. Its osmolality ranges from approximately 1500 mOsm/kg (50% solution ...

*Superparamagnetic relaxometry

Contrast Media & Molecular Imaging. 7 (3): 308-319. doi:10.1002/cmmi.499. PMID 22539401. De Haro, Leyma P.; Karaulanov, Todor; ... Contrast media & molecular imaging. 7 (3). doi:10.1002/cmmi.499. ISSN 1555-4309. PMC 3883306 . PMID 22539401. Hathaway, HJ; ... Since only NP that are bound to cells are measured by the SPMR process, high contrast is achieved between targeted cells in the ...

*Olfactory ensheathing glia

Contrast Media & Molecular Imaging. 7 (4): 403-410. doi:10.1002/cmmi.1465. Honore, Axel; Le Corre, Stéphanie; Derambure, Céline ...

*Medication

contrast media For euthanasiaEdit. See also: Barbiturate § Other non-therapeutical uses ...

*Medication

contrast media For euthanasiaEdit. See also: Barbiturate § Other non-therapeutical uses ...

*Medication

contrast media. For euthanasiaEdit. See also: Barbiturate § Other non-therapeutical uses ...

*Beta blocker

Contrast media are not contraindicated in patients receiving beta blockers.[55] Diabetes mellitus[edit]. Beta-blockers can ... Guardian News and Media Limited. Retrieved March 7, 2018.. *^ Elman MJ, Sugar J, Fiscella R, Deutsch TA, Noth J, Nyberg M, ... "Beta blockers and intravenous roentgen contrast materials: Which risks do exist?" (PDF). European Journal of Internal Medicine ...

*Agfa-Gevaert

Acquisition of Insight Agents, a European developer and producer of contrast media. ... By contrast, Agfaphoto branded photographic films are not made by Agfa-Gevaert at all, originally having been made by the now ... Agfaphoto films are now produced by Fujifilm in Japan for Lupus Imaging Media. ...

*Poppyseed oil

A new contrast medium emulsion for lymphography (author's transl)]". RöFo : Fortschritte Auf Dem Gebiete Der Röntgenstrahlen ... In contrast, pharmaceutical uses of poppyseed oil began in the 20th century. Iodized poppyseed oil was the subject of a 1959 ... In 1976 a contrast agent for imaging the liver and spleen using computed tomography was proposed: AG 60.99, an emulsion of ... Some users consider "sun-thickened" poppyseed oil to be the best painting medium. Poppyseed oil has been used for painting for ...

*Basophil

Böhm I, Speck U, Schild HH (April 2011). "Pilot study on basophil activation induced by contrast medium". Fundamental & ... induced by contrast medium), the BAT is of great impact.[14] Basopenia (a low basophil count) is difficult to demonstrate as ...

*Iohexol

ACR Manual on Contrast Media v10.3. 2017 (PDF). American College of Radiology. 2017. p. 6. ISBN 9781559030120. Archived (PDF) ... "Nycodenz®: A universal density gradient medium" Archived 2015-02-26 at the Wayback Machine., Axis-Shield Density Gradient Media ... Springer Science & Business Media. p. 235. ISBN 9781447117551. Archived from the original on 2017-01-01. Broe, Marc E. de; ... Springer Science & Business Media. p. 325. ISBN 9789401590884. Archived from the original on 2017-01-01. "WHO Model List of ...

*Poverty in Japan

However several media reports contrast this. In Japan, relative poverty is defined as a state at which the income of a ...

*Line drawing algorithm

On continuous media, by contrast, no algorithm is necessary to draw a line. For example, oscilloscopes use natural phenomena to ... On discrete media, such as pixel-based displays and printers, line drawing requires such an approximation (in nontrivial cases ... A line drawing algorithm is a graphical algorithm for approximating a line segment on discrete graphical media. ...

*Multiple sclerosis

Ferré JC, Shiroishi MS, Law M (November 2012). "Advanced techniques using contrast media in neuroimaging". Magn Reson Imaging ... Play media A person with MS can have almost any neurological symptom or sign, with autonomic, visual, motor, and sensory ... Pullman D, Zarzeczny A, Picard A (2013). "Media, politics and science policy: MS and evidence from the CCSVI Trenches". BMC Med ... This theory received significant attention in the media and among those with MS, especially in Canada. Concerns have been ...

*Barium sulfate suspension

It is a non-iodinated contrast media. Barium sulfate has been known since the Middle Ages. In the United States it had come ... Barium sulfate suspension, often simply called barium, is a contrast agent used during X-rays. Specifically it is used to ...

*Radiocontrast agent

Contrast media are primarily used to visualize vessels and changes in tissues on radiography and CT. Contrast media can also be ... "Adverse Reactions to Ionic and Nonionic Contrast Media. A Report from the Japanese Committee on the Safety of Contrast Media". ... Iodine-based contrast media are water-soluble. These contrast agents are sold as clear, colorless water solutions, with the ... Iodine-based contrast media are usually classified as ionic or non-ionic. Both types are used most commonly in radiology due to ...

*Error correction code

In contrast, convolutional codes are typically decoded using soft-decision algorithms like the Viterbi, MAP or BCJR algorithms ... Sphere Packings, Lattices and Groups, By J.H. Conway, N.J.A. Sloane, Springer Science & Business Media, 9 Mar 2013 - ... In contrast to classical block codes that often specify an error-detecting or error-correcting ability, many modern block codes ...

*Safety of magnetic resonance imaging

Iodinated contrast medium is routinely used in CT and the main adverse events are anaphylactoid reactions and nephrotoxicity. ... The use of gadolinium-based contrast media in pregnancy is an off-label indication and may be administered only in the lowest ... Webb JA; Thomsen HS (2013). "Gadolinium contrast media during pregnancy and lactation". Acta Radiol. 54 (6): 599-600. doi: ... MRI without contrast agents is the imaging mode of choice for pre-surgical, in-utero diagnosis and evaluation of fetal tumors, ...
PURPOSE:. To investigate the possibility of detecting cardiac transplant rejection and determining its degree of severity with magnetic resonance (MR) imaging with a blood pool contrast agent.. MATERIALS AND METHODS:. Rat allogeneic (PVG to Wistar/Kyoto, n = 9) and syngeneic (Wistar/Kyoto to Wistar/Kyoto, n = 6) heterotopic heart transplantations were performed. On the 2nd and 6th postoperative days, an ultrasmall superparamagnetic iron oxide, or USPIO, contrast agent was injected intravenously at a dose of 2 mg of iron per kilogram of body weight. The injection was followed by three-dimensional T1-weighted MR imaging of the heart grafts with an imaging time of approximately 2 minutes for each image for 44 minutes. The signal intensity (SI) was measured in the myocardium over time, and the relative enhancement was calculated. After the 6th day, the rats were sacrificed, and the morphology of the transplanted hearts was assessed histologically. The CIs for the difference of the means on day 2 and ...
TY - JOUR. T1 - Liver perfusion changes occurring during pancreatic islet engraftment. T2 - A dynamic contrast-enhanced magnetic resonance study. AU - Esposito, A.. AU - Palmisano, A.. AU - Maffi, P.. AU - Malosio, M. L.. AU - Nano, R.. AU - Canu, T.. AU - De Cobelli, F.. AU - Piemonti, L.. AU - Ironi, G.. AU - Secchi, A.. AU - Del Maschio, A.. PY - 2014/1. Y1 - 2014/1. N2 - The aim of this study was to investigate liver microvascular adaptation following the intraportal infusion of pancreatic islets (pancreatic islet transplantation [islet-tx]) in diabetic patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). DCE-MRI was performed before and 7 days after islet-tx in six diabetic patients. Initial area under curve (AUC60) and volume transfer coefficient (Ktrans) were assessed as markers of liver perfusion. Clinical and metabolic monthly follow-up was performed in all patients, considering fasting C-peptide and β-score as main indices of graft function. High variability ...
This study intends to assess the ability of contrast-enhanced ultrasound in the detection of benign and malignant ovarian masses compared to unenhanced ultrasound.. By using an intravascular contrast agent, this noninvasive and feasible imaging technique will allow the investigators to define specific microcirculation patterns in 100 women with ovarian lesions.. The intravascular contrast agent properties will be compared between benign and malignant adnexal masses.. The final purpose of this ultrasonography is to allow the early detection of tumors and to improve the characterization between benign and malignant lesions. ...
TY - GEN. T1 - Segmentation and classification of breast tumor using dynamic contrast-enhanced MR images. AU - Zheng, Yuanjie. AU - Baloch, Sajjad. AU - Englander, Sarah. AU - Schnall, Mitchell D.. AU - Shen, Dinggang. PY - 2007/12/1. Y1 - 2007/12/1. N2 - Accuracy of automatic cancer diagnosis is largely determined by two factors, namely, the precision of tumor segmentation, and the suitability of extracted features for discrimination between malignancy and benignancy. In this paper, we propose a new framework for accurate characterization of tumors in contrast enhanced MR images. First, a new graph cut based segmentation algorithm is developed for refining coarse manual segmentation, which allows precise identification of tumor regions. Second, by considering serial contrast-enhanced images as a single spatio-temporal image, a spatio-temporal model of segmented tumor is constructed to extract Spatio-Temporal Enhancement Patterns (STEPs). STEPs are designed to capture not only dynamic ...
Summary:Intravenous contrast media, specifically the gadolinium chelates, are well accepted for use in the clinical practice of magnetic resonance imaging. The gadolinium chelates are considered to be very safe and lack (in intravenous use) the nephrotoxicity found with iodinated contrast media. Min
North America, Europe, Asia-Pacific, and Rest of the World (RoW) are the regions considered for a geographic analysis of the global contrast media/contrast agents market. North American contrast media/contrast agents market is expected to account for the largest share of the global contrast media/contrast agents market. However, the Asia Pacific contrast media/contrast agents market is expected to grow at the highest CAGR in the forecast period. This growth can be attributed to the increasing R&D investments and favorable demographic scenario in China, rising aging population and cancer incidence in Japan, growing investments in the Indian radiology market, and growing focus of market players & increasing government support in other APAC countries.. The prominent players in the global contrast media/contrast agents market include GE Healthcare (US), Bracco Imaging S.p.A. (Bracco) (Italy), Bayer HealthCare (Bayer) (Germany), and Guerbet Group (Guerbet) (France).. Don t miss out on business ...
Antivascular treatments can either be antiangiogenic or targeting established tumour vasculature. These treatments affect the tumour microvasculature and microenvironment but may not change clinical measures like tumour volume and growth. In research on antivascular treatments, information on the tumour vasculature is therefore essential. Preclinical research is often used for optimization of antivascular drugs alone or in combined treatments. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an in vivo imaging method providing vascular information, which has become an important tool in both preclinical and clinical research. This review discusses common DCE-MRI imaging protocols and analysis methods and provides an overview of preclinical research on antivascular treatments utilizing DCE-MRI.
Currently there are no approved biomarkers for the pre-symptomatic diagnosis of Alzheimers disease (AD). Cathepsin-D (Cat-D) is a lysosomal protease that is present at elevated levels in amyloid plaques and neurons in patients with AD and is also elevated in some cancers. We have developed a magnetic resonance imaging (MRI)/fluorescent contrast agent to detect Cat-D enzymatic activity. The purpose of this study was to investigate the cellular and tissue uptake of this MRI/fluorescent contrast agent. The agent consists of an MRI probe [DOTA-caged metal ion (Gd3+ or Tm3+)] and a fluorescent probe coupled to a cell-penetrating-peptide sequence by a Cat-D recognition site. The relaxivity of Gd3+-DOTA-CAT(cleaved) was measured in 10% heat-treated bovine serum albumin (BSA) phantoms to assess contrast efficacy at magnetic fields ranging from 0.24 mT to 9.4 T. In vitro, Tm3+-DOTA-CAT was added to neuronal SN56 cells over-expressing Cat-D and live-cell confocal microscropy was performed at 30 min. ...
Heterogeneity is a common finding within tumours. We evaluated the imaging features of tumours based on the decomposition of tumoural dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data to identify their prognostic value for breast cancer survival and to explore their biological importance. Imaging features (n = 14), such as texture, histogram distribution and morphological features, were extracted to determine their associations with recurrence-free survival (RFS) in patients in the training cohort (n = 61) from The Cancer Imaging Archive (TCIA). The prognostic value of the features was evaluated in an independent dataset of 173 patients (i.e. the reproducibility cohort) from the TCIA I-SPY 1 TRIAL dataset. Radiogenomic analysis was performed in an additional cohort, the radiogenomic cohort (n = 87), using DCE-MRI from TCGA-BRCA and corresponding gene expression data from The Cancer Genome Atlas (TCGA). The MRI tumour area was decomposed by convex analysis of mixtures (CAM), resulting
TY - JOUR. T1 - Glomerular filtration rate estimated after multiple injections of contrast medium during angiography. AU - Boijsen, M.. AU - Granerus, G.. AU - Jacobsson, L.. AU - Björneld, L.. AU - Aurell, M.. AU - Tylen, Ulf. PY - 1988. Y1 - 1988. N2 - In twenty-six patients referred for angiography, clearance of contrast medium was determined with x-ray fluorescence analysis after multiple injections of contrast medium. A formula for correction of the injected amount, which takes into consideration the different times of contrast medium injections, approximating the total injected amount into one injection, was used. A single injection clearance of 51Cr-EDTA was determined at the same time. the results showed a good correlation between the clearance of contrast medium after multiple injections and the 51Cr-EDTA clearance after a single injection (r=0.945). the correlation between contrast medium clearance calculated without correction for the different injection times, and 51Cr-EDTA ...
Abstract: Significant progress has been made in recent years in the development of effective ultrasonic contrast agents for inducing better image contrast of certain anatomic structures in the body for diagnostic purposes. An ideal ultrasonic contrast agent should have the following characteristics: (1) be nontoxic, (2) be capable of producing sufficient contrast via intravenous injection, and (3) have a long persistence time. Gaseous contrast agents such as Albunex[sup (registered)] (Molecular Biosystems), Echovist[sup (registered)] and Levovist[sup (registered)] (Schering), and EchoGen[sup (registered)] (Sonus) have been shown to satisfy a majority of these requirements. Albunex[sup (registered)] was approved in 1994 by the FDA for clinical use. The most intriguing application of these contrast agents is in harmonic pulse-echo and Doppler imaging since nonlinear resonance of microairbubbles would yield echoes at the harmonics of the incident frequency. If detection is made at one of these ...
Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Biomarker for the Pharmacological Response of PTK787/ZK 222584, an Inhibitor of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, in Patients With Advanced Colorectal Cancer and Liver Metastases: Results From Two Phase I ...
Acute adverse reactions to contrast media will occur at a certain rate. Non-ionic iodinated contrast is said to have an adverse reaction rate of about 0.6 to 3.1% [6-10]. This rate is said to be about 0.07 to 0.67% for gadolinium contrast media [6-9].. The ACR Manual on Contrast Media [1] and EUSR Guidelines on Contrast Media [2] recommend premedication for patients at risk for adverse reactions to contrast, but the definition of at-risk has some variation among protocols and studies. The ACR Manual states patients with a history of adverse reactions should be premedicated, but does not elaborate on the degree of the reaction. The ESUR Guidelines, on the other hand, includes patients with a history of moderate or severe reactions. When following the ESUR Guidelines, patients with history of mild reactions to contrast undergo contrast enhanced examinations without premedication. (We chose to follow and reference the older versions of the ACR Manual and ESUR Guidelines, as these were the ones ...
The Global Contrast Media Market is going to continue with the same trends of growth during the forecast period. The major factors influencing the growth of the market include increasing technology advancement in contrast medium, increasing prevalence of cancer and cardiac diseases, growth in emerging markets for imaging technology, increasing demand for diagnostics, and image guide procedures and various others. Whereas, the risk of side effects and adverse effects of the contrast media may hamper the growth of the market. Exclusive Sample Copy @https://www.marketresearchfuture.com/sample_request/1284 .. Contrast media are substances which are utilized to improve the contrast of fluids in the body during medical imaging. It is basically used to enhance the visibility of blood vessels and GI tract. The global contrast media market is growing with the steady pace; mainly due to the increasing prevalence of different diseases such as GIT diseases and cardiac diseases. According to a recent study ...
Dynamic contrast-enhanced (DCE)-MRI is useful to assess the early effects of drugs acting on tumor vasculature, namely anti-angiogenic and vascular disrupting agents. Ultra-high-field MRI allows higher-resolution scanning for DCE-MRI while maintaining an adequate signal-to-noise ratio. However, increases in susceptibility effects, combined with decreases in longitudinal relaxivity of gadolinium-based contrast agents (GdCAs), make DCE-MRI more challenging at high field. The aim of this work was to explore the feasibility of using DCE-MRI at 11.7 T to assess the tumor hemodynamics of mice. Three GdCAs possessing different molecular weights (gadoterate: 560 Da, 0.29 mmol Gd/kg; p846: 3.5 kDa, 0.10 mmol Gd/kg; and p792: 6.47 kDa, 0.15 mmol Gd/kg) were compared to see the influence of the molecular weight in the highlight of the biologic effects induced by combretastatin A4 (CA4). Mice bearing transplantable liver tumor (TLT) hepatocarcinoma were divided into two groups (n = 5-6 per group and per ...
Envision uses non-ionic contrast media. This is the safest intravenous contrast media available.. Sometimes an injection of contrast media is indicated to enhance diagnostic accuracy of the examination and enhance the quality. Following an injection of contrast media, you may experience a sensation of heat, an unusual taste or smell and a tingling sensation in the pelvic area. These symptoms are common and very transient. The contrast is eliminated from the body by the kidneys and is excreted in the urine within hours of the initial injection. Patients are encouraged to drink additional clear fluids following their examination to assist in the filtration of the kidneys.. Occasionally, patients can experience minor allergic reactions such as hives. In rare cases, a major allergic reaction can occur. Envision staff are trained in the management of allergic reactions and all sites that administer intravenous contrast media are equipped with emergency medications and equipment, should a patient ...
Although effective in promoting the prevention of SCD, current risk stratification strategies in HCM patients do not identify all at-risk patients, largely as a result of the substantial heterogeneity in clinical and phenotypic expression of this genetic disease.2,3,5,8,42 Because SCD can occur in HCM patients considered to be at low risk, identification of additional markers to allow more precise selection of those patients who may benefit from primary prevention ICD therapy represents a major clinical aspiration.3,28 Recently, considerable interest in using contrast-enhanced CMR to improve the risk stratification model has emerged.43-48 However, available data on the prognostic value of CMR do not provide an opportunity to specifically predict SCD risk for individual HCM patients.28,29 In the present large, multicenter HCM cohort, we have investigated LGE as a predictor of SCD and other adverse disease consequences among a predominantly lower-risk cohort of HCM patients.. Our data show that in ...
Contrast Media Injectors (Diagnostic Imaging) - Global Market Analysis and Forecast Model has complete details about market of Contrast Media Injectors (Diagnostic Imaging) industry, Contrast Media Injectors (Diagnostic Imaging) analysis and current trends. Contrast Media Injectors (Diagnostic Imaging) - Global Market Analysis and Forecast Model Summary Contrast Media Injectors (Diagnostic Imaging) - Global Market Analysis and Forecast Model is built to visualize quantitative market trends within Diagnostic Imaging therapeutic area. Contrast Media Injectors are devices used to inject contrast medi.
Early buyers will receive 10% customization on reports.. This report studies the global contrast media/contrast agentsmarket for the forecast period of 2016 to 2021. This market is expected to reach a value of USD 5.44 Billion by 2021, from an estimated value of USD 4.46 Billion in 2016, at a CAGR of 4.1%.. The prominent players in the global contrast media/contrast agents market include Bayer HealthCare (Germany), GE Healthcare (U.S.), Guerbet Group (France), and Bracco Imaging S.p.A. (Italy). These companies hold a dominant position in the contrast media/contrast agents market mainly due to their well-established presence in the field of genomics, presence in over 50 countries, high R&D investments, and strong sales and distribution force. Other players operating in this market include Lantheus Medical Imaging (U.S.), nanoPET Pharma GmbH (Germany), CMC Contrast AB (Sweden), Daiichi Sankyo (Japan), and Subhra Pharma Private Limited (India).. The global contrast media/contrast agentsmarket has ...
Many CT studies require intravenous contrast agent. This is a special fluid containing iodine that enhances the blood vessels and certain organs and allows them to be better visualised, highlighting any abnormalities. If your examination requires an intravenous contrast injection, you will be asked whether you have a history of allergies or asthma; and whether you are on diabetic medication. Oral contrast media are not usually required for CT studies of the brain and spine. ...
TY - JOUR. T1 - Effects of contrast media on renal function and subcellular morphology in the dog. AU - Katzberg, Richard W. AU - Pabico, Rufino C.. AU - Morris, Thomas W.. AU - Hayakawa, Katsumi. AU - McKenna, Barbara A.. AU - Panner, Bernard J.. AU - Ventur, Janine A.. AU - Fischer, Harry W.. PY - 1986. Y1 - 1986. N2 - The effects of intravenous contrast media (CM) on renal excretory function and subcellular morphology are examined in this animal investigation. A decrease in GFR (12.0 ±1.6 vs. control 30.2 ± 2.S ml/min) was observed when renal function was evaluated by means of the artero-venous extraction method with Tc99m DTP A and the anticipated inverse relationship to urinary flow (Vml/min) noted. An artifactual increase in GFR (43.S ± 10.0 vs. control 39.1 ± 3.8 ml/min) was observed using the timed urinary clearance of inulin. V(ml/min) increased four-fold (0.6 ± 0.16 control vs. 2.7 ± 0.7 ml/min; P ,.05) over the first five minutes after injection of CM. Urine osmolality initially ...
OBJECTIVES The aim of this study was to investigate the feasibility of using contrast-enhanced ultrasound (CEUS) in experimental breast cancer bone metastases and its utilization for assessment of early antiangiogenic treatment response in these lesions. MATERIALS AND METHODS Nude rats bearing bone metastases (n = 20) were treated with the antiangiogenic tyrosine kinase inhibitor sunitinib daily from days 30 to 35 after MDA-MB-231 tumor cell inoculation (n = 10) and compared with sham-treated controls (n = 10). Imaging with ultrasound (US) and magnetic resonance imaging (MRI) was performed on days 30, 32, and 35 after tumor cell inoculation to determine tumor volume and parameters of vascularization in bone metastases. Contrast-enhanced US images were used to calculate wash-in and wash-out values, peak enhancement, and area under the curve from time intensity curves. In addition, a quantitative analysis software was used to determine regional blood volume and flow as well as filling times within bone
CMR adenosine first pass perfusion yields excellent results for the detection of significant coronary artery disease. As in patients after coronary artery bypass grafts (CABG) myocardial perfusion is more complex and additionally the kinetic of a first pass bolus may by altered due to different distances through the bypasses and/or native vessels, this patient group has been excluded from most published studies. Parameters like speed of contrast wash-in (upslope, time to 50% or peak enhancement) and peak enhancement are indirectly used for visual analysis and may be altered post CABG imitating perfusion defects without significant stenosis. In this case, adenosine perfusion would be an inadequate diagnostic test. ...
Microparticles which are less than 12 μm in size and are formed of or comprise a solid lipophilic group-containing compound having an HLB value less than about 20 produce a long lived ultrasonically echogenic entity in aqueous liquid and are useful as left heart ultrasonic contrast image enhancing agents. Contrast media for ultrasonic diagnostics comprising a liquid vehicle containing (a) suspended therein microparticles of a mixture of at least one (C8 -C20)-fatty acid and at least one solid that is not a surfactant and (b) microbubbles, are especially effective upon ultrasonic imaging after intravenous administration, for the contrasting of both the right heart and left heart, of the myocardium, as well as other organs, such as liver, spleen, and kidneys.
Absolute cerebral perfusion parameters were obtained by dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) carried out using different contrast-agent administration protocols. Sixteen healthy volunteers underwent three separate DSC-
Contrast-enhanced magnetic resonance angiography (MRA) employs the use of blood pool contrast agents (CA) such as gadolinium (Gd3+) complexes that allow for delayed phase arterial
Image acquisition strategies. Principal contrast mechanisms in MRI emerge from the relaxation properties of tissue water (or fat) hydrogen nuclei in the scanner magnetic field after undergoing radiofrequency excitation. These properties can be manipulated to reflect features of the molecular and physiologic environment of a tissue. T1-weighted images emphasize the rate (different for different tissue types) at which energy is redistributed between these nuclei and the tissue as a whole. T2*-weighted images emphasize the different rates at which the same nuclei lose phase coherence with one another and the way that this process is affected by local variations in field strength due to differences in magnetic susceptibility between tissues. Conventional gadolinium chelate-based contrast media affect T1-weighted images causing a signal increase, and T2*-weighted images causing a signal decrease.. Nearly all clinical DCE-MRI is done at 1.5 T. The data have a typical spatial resolution of a few ...
Dynamic Contrast-Enhanced Magnetic is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. The method assists
We describe here in a large group of patients qualitative and semiquantitative DCE-MRI parameters that distinguish sMM from normal controls. We also provide evidence that this technique can identify a distinct patient population in NRC that presents with a pathologic DCE-MRI. Referring to this, pathologic findings according to our analysis were defined by a pattern of strongly increased microcirculation (diffuse variant), focal hotspots in the investigated area (focal pattern), or by an amplitude A above the upper limit of normal controls. It has to be mentioned that a diffuse variant pattern cannot be distinguished from a focal pattern affecting the whole vertebra, which may explain in part why those two patterns seem to seem exclusively in the same, namely the symptomatic patient group.. Different patterns of bone marrow involvement of MM in conventional as well as DCE-MRI have been described concordantly by different authors (14, 23, 29, 30). Diffuse distribution of microcirculation was found ...
We read with great interest the article by Jablonowski et al. (1) showing that contrast-enhanced cardiac magnetic resonance (ce-CMR) overestimates infarct size at 6 h post-reperfusion compared with pathology and that infarct imaging timing by ce-CMR is critical. Although this is not an entirely new finding, the careful and meticulous work performed by the authors demonstrates the rapidly changing nature of acute infarction and reperfused myocardial tissue (2). If this experimental work focuses precisely on infarct sizing, the reader is left with several open questions.. On observation of the different figures from this article (Figures 3 and 6), there is a 50% reduction of infarct size by ce-CMR, whereas there is a 26% increase in myocardial salvage and a 30% reduction in extracellular volume by pathology in the infarcted myocardium and adjacent areas between day 0 and day 7. In this rapid series of myocardial tissue changes, it is hard for the reader to understand that the same changes do not ...
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A contrast medium injector for injecting a patient with contrast medium for a CT scan is programmed to provide an injection protocol that is a representation of an ideally defined exponential curve with an initial injection rate decaying at an exponential rate. This has been found to produce a uniform vascular enhancement for the scanning of a patients blood vessels. The particular exponential decay coefficient which has been found to be optimal is directly proportional to the cardiac output divided by the patients weight and is approximated at 0.01 for a typical human.
Purpose To evaluate the feasibility of ultrafast dynamic contrast-enhanced (UF-DCE) magnetic resonance imaging (MRI) with compressed sensing (CS) for the separate identification of breast arteries/veins and perform temporal evaluations of breast arteries and veins with a focus on the association with ipsilateral cancers. Materials and Methods Our Institutional Review Board approved this study with retrospective…
Following administration of Gadolinium there can be three possible enhancement kinetic curves for a lesion on breast MRI (these are also applied in other organs such as prostate MRI). These are sometimes termed the Kuhl enhancement curves. type ...
The invention relates to ultrasonic contrast agents composed of microparticles which contain a gas and polyamino-dicarboxylic acid-co-imide derivatives, to processes for their preparation and to their use as diagnostic and therapeutic agents.
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
This group comprises X-ray, MRI and Ultrasound contrast media. The X-ray contrast media are subdivided into iodinated and non-iodinated compounds, and are further classified according to water solubility, osmolarity and nephrotropic/hepatotropic properties. High osmolar substances correspond mainly to ionic substances, except from ioxaglic acid, which is classified together with the non-ionic substances. MRI contrast media are subdivided according to magnetic properties. ...
Introduction: Contrast-induced nephropathy (CIN) is an important adverse outcome of coronary angiography/intervention. The role of pre-procedural statins in preventing CIN is unclear. Furthermore, the relative efficacy of different statins is unknown. Accordingly, we sought to perform a network meta-analysis to address this question.. Methods: We performed a Bayesian network meta-analysis of randomized controlled trials that evaluated the impact of statin therapy prior to coronary angiography/intervention on post-procedure outcomes. The primary outcome was the incidence of CIN assessed as an increase in serum creatinine ,0.5 mg/dl or , 25% from baseline at 48-72 hours; need for hemodialysis (HD) at 30 days was the secondary outcome. Different types and doses of statins were pooled and compared with Bayesian random-effects models, calculating pooled odds ratios (OR) and associated 95% credible intervals (95% CrI) for the Bayesian analysis.. Results: A total of 14 studies (9 statin vs. placebo; 5 ...
In medicine, every detail counts - we make it visible.. Organs and tissues of the body are very difficult to differentiate from one another in radiological diagnostics. Differentiation is frequently only possible with the use of contrast media.. With contrast media injectors for use in computed tomography (CT), magnetic resonance imaging (MRI) and angiography, ulrich medical® offers a complete product portfolio.. Our contrast media injectors have already been successfully used for more than 30 years in radiology practices and hospitals. They offer users unique solutions which are only available from ulrich medical®. Their user-friendly handling, superior "Made in Germany" quality and proven hygiene safety make these products indispensable in everyday practice.. ...
MarketResearchReports.Biz announces addition of new reportBRIC Contrast Media Injectors Market Outlook to 2020to its database BRIC Contrast Media Injectors Market Outlook to 2020, provides key market data on the BRIC Contrast Media Injectors market. The report provides value, in millions of US dollars, and volume (in units) and average price data (in US dollars), within market categories CT Injectors, Interventional Cardiology/Angio Injectors and MRI Injectors. View Full Report at http://www.marketresearchreports.biz/analysis/195610 The report also provides company shares and distribution shares data for each of these market categories, and global corporatelevel profiles of the key market participants, pipeline ...
Perfusion data characterize the regional blood flow in human tissue. In the diagnosis of the Coronary Heart Disease, they are acquired to detect hypoperfused regions of the myocardium (heart muscle) at an early stage or to evaluate the hemodynamical relevance of a known pathologic vessel narrowing. For each voxel in the data, a time-intensity curve describes the enhancement of a contrast agent. Parameters derived from these curves characterize the regional perfusion and have to be integrated for diagnosis. The diagnostic evaluation of this multi-field data is challenging and time-consuming due to its complexity. We tackle this problem by developing a glyph-based integrated visualization of perfusion parameters in 3D-space with the patient-individual ventricular anatomy as context information. Besides the assessment of myocardial perfusion, current cardiac imaging technology allows for the investigation of myocardial contractility as well as for the detection of non-viable tissue. The combined ...
... This study covers the world outlook for contrast media injectors - Market research report and industry analysis - 12882381
Adverse reactions to contrast agents range from a mild inconvenience, such as itching associated with hives, to a life-threatening emergency. Renal toxicity is a well known adverse reaction associated with the use of intravenous contrast material. Other forms of adverse reactions include delayed allergic reactions, anaphylactic reactions, and local tissue damage. Previous allergic reactions to contrast material, asthma, and allergies are factors associated with an increased risk of developing an adverse reaction. Pretreatment of patients who have such risk factors with a corticosteroid and diphenhydramine decreases the chance of allergic reactions, including anaphylaxis, renal failure, or a possible life-threatening emergency. Awareness of the different types of risk factors and prescreening for their presence allows for early recognition and prompt treatment. Prophylactic treatment before administration of contrast material can prevent potential adverse reactions. If such reactions do occur, prompt
Nough, H., Eghbal, F., Soltani, M., et al. (2013) Incidence and main determinants of contrast-induced nephropathy following coronary angiography or subsequent balloon angioplasty. CardioRenal Medicine, 3, 128-135.
The report Global Contrast Media Market - Size, Outlook, Trends, and Forecasts (2018 - 2024) the Global Contrast Media Market expected to reach USD X Million by the year 2024, at a CAGR of 5.3% during forecast period. The contrast media market has onlooker various plans in products and their concurrence to meet the needs of patients and radiologists worldwide
A new imaging technology may hold the key to not only stopping heart attacks in their tracks but also preventing them for ever occurring.
As part of a number of examinations, you may need to have an injection of Radiographic Contrast Medium. This is a colourless dye that shows up on x-ray pictures and scans, and is used to highlight structures in the body that cant be seen without it. This contrast agent causes no complication in the vast majority of people who have it.. There are risks involved with any medical procedure; and in a small number of people, certain side effects can occur following an injection of contrast agent.. Many people describe a feeling of warmth around their body and an unusual taste in the mouth. This is normal and lasts for a minute or two. Brief nausea may occur. Some people develop minor allergic symptoms such as hives, itchiness or a stuffy nose or eyes.. Your doctor (who requested this test) is aware of the risks, and has recommended the test knowing the benefits of the examination far outweigh the tiny risk involved.. ...
We tested the hypothesis that differences in proximal and distal contrast bolus arrival times may result in insufficient vascular signal in the distal part of the aortoiliofemoral territory with routinely used timing techniques. The difference in arrival time of the contrast medium bolus between the aorta and the common femoral arteries was measured in 14 patients undergoing magnetic resonance angiography of the aortoiliac arteries. A dual-station test bolus technique adjusting for this difference was evaluated. The variation coefficient of the signal intensity in six defined locations and signal intensities (SI) normalised to fat were calculated. Comparisons were made with findings in 13 patients examined with a fluoroscopically triggered timing technique (BolusTrak, Philips Medical Systems, Best, The Netherlands). The difference in bolus arrival time between proximal and distal vessels was 0-7 s. In 3 of 14 patients it was 5.6-7 s. There was a tendency towards a lower mean variation ...
Molecular Imaging (MI) and Magnetic Resonance (MR) contrast agents are at the forefront of medical research and drug discovery.. Current research in MI focusses on e.g. simultaneous microscopy and whole body imaging, so-called "multimodal" imaging. MR enables high spatial resolution and the ability to simultaneously obtain physiological and anatomical information, whereas optical (fluorescence) imaging allows for rapid screening.. Combining the advantages of both imaging modalities allows: e.g. co-validation of the accumulation of targeted MR contrast agents at a target site. We are combining components of both imaging modalities in the same compound.. ...
Purpose Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) provides an advantage over conventional MRI in that DCE-MRI provides anatomical, physiological, and hemodynamic information about neoplastic lesions. Our aim in this study was to evaluate spinal metastases from hypervascular renal cell carcinoma (RCC) and hypovascular prostate carcinoma (PC) using a T1 DCE-MRI perfusion technique and to assess the sensitivity and specificity of the perfusion parameters obtained. Materials & Methods A total of 40 patients with spinal metastases and either PC or RCC as the primary tumor were studied. DCE perfusion parameters-vascular permeability (Ktrans), plasma volume (Vp), wash-in, and peak-enhancement were measured to assess their potential as discriminators of tumor histology. A Mann-Whitney U test, at a significance level of p≤0.01, was performed to quantify and compare the significances of the perfusion parameters of PC and those of RCC. Results Of the four perfusion parameters ...
Fluorescent molecules targeted to reveal information on tissue function have been used as research tools in ex vivo and subsurface characterization of diseased tissue for years. Exploiting this specificity for in vivo imaging through centimeters of tissue is a challenging problem due to high signal attenuation from light absorption and elastic scattering. Therefore, diagnostic imaging of exogenous contrast agents through tissue requires model-based techniques which even under the best of circumstances suffer from relatively poor spatial-resolution and non-uniform sensitivity throughout the imaging field. These challenges are addressed by incorporating tissue structural information derived from a highly resolved clinical imaging modality into diffuse fluorescence and spectrally-constrained absorption tomographic image reconstruction routines. A multichannel spectroscopic molecular imaging system capable of collecting spectrally-resolved near-infrared transmission and luminescent data from within ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Abstract- Medical imaging is one of the most important application areas of digital image processing. Processing of various medical images is very much helpful to visualize and extract more details from the image. Many techniques are available for enhancing the quality of medical image. For enhancement of medical images, Contrast Enhancement is one of the most acceptable methods. Different contrast enhancement techniques i.e. Linear Stretch, Histogram Equalization, Region based enhancement, Adaptive enhancement are already available. Choice of Method depends on characteristics of image. This paper deals with contrast enhancement of MRI images and presents here a new approach for contrast enhancement based upon Adaptive Neighborhood technique. A hybrid methodology for enhancement has been presented. Comparative analysis of proposed technique against the existing major contrast enhancement techniques has been performed and results of proposed technique are promising. Keywords: Histogram Equalization,
TY - JOUR. T1 - Endoluminal contrast for abdomen and pelvis magnetic resonance imaging. AU - Gupta, Mohit K.. AU - Khatri, Gaurav. AU - Bailey, April. AU - Pinho, Daniella F.. AU - Costa, Daniel. AU - Pedrosa, Ivan. PY - 2016/7/1. Y1 - 2016/7/1. N2 - Magnetic resonance (MR) imaging of the abdomen and pelvis can be limited for assessment of different conditions when imaging inadequately distended hollow organs. Endoluminal contrast agents may provide improved anatomic definition and detection of subtle pathology in such scenarios. The available routes of administration for endoluminal contrast agents include oral, endorectal, endovaginal, intravesicular, and through non-physiologic accesses. Appropriate use of endoluminal contrast agents requires a thorough understanding of the clinical indications, available contrast agents, patient preparation, and interaction of the contrast agent with the desired MR imaging protocol. For example, biphasic oral enteric contrast agents are preferred in MR ...
150ml 200ml 60ml DSA High Pressure Contrast Media Injector for Bayer Medrad Mark V Provis(id:9741514). View product details of 150ml 200ml 60ml DSA High Pressure Contrast Media Injector for Bayer Medrad Mark V Provis from Shenzhen X-Way Medical Technology Co.,Ltd manufacturer in EC21
At the Institute for Basic Science (IBS) in South Korea, researchers have developed a new type of MRI contrast agent that only lights up when near a target
Press Release issued Mar 26, 2014: Reportstack, provider of premium market research reports announces the addition of France Contrast Media Injectors Market Outlook to 2020 market report to its offering France Contrast Media Injectors Market Outlook to 2020
As stated in the report North America holds a significant share in the market. The trend is unlikely to change and North America may continue holding its position. The growth witnessed is attributable to high presence of key developers in nations such as Canada and U.S.. The Asia Pacific Contrast Media market is expected to expand at a promising CAGR during the forecast period. The constantly improving healthcare infrastructure in the region is expected to contribute to Asia Pacific market expansion.. The analysis conducted in the report is based on industry leading tools and techniques. The report prepared by Fortune Business Insights, offers innovative strategies based on various analysis. The information offered is collected from reliable primary and secondary sources. The report also provides information about key companies operating in the market.. Major Table of Content For Contrast Media Market: ...
By observing the real-time behavior of focal liver lesions at three vascular phases (arterial, portal-venous, and late), contrast-enhanced ultrasound (CEUS) has been successfully applied to differentiate benign from malignant hepatic nodules. In recent years, numerous studies highlighted the usefulness of CEUS also for other applications such as abdominal trauma, renal, pancreatic, thyroid, and inflammatory bowel diseases, supporting its role even in differentiating benign from malignant splenic nodules. Therefore, the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) recently updated the guidelines for the use of ultrasound contrast agents in clinical practice, pointing out the indication to characterize splenic parenchymal inhomogeneity or suspected lesions found on conventional ultrasound (BUS ...
OBJECTIVE The purpose of this study was to compare two time delays between injection of contrast material and helical CT scanning to determine relative conspicuity of hepatic metastases. SUBJECTS AND METHODS Twenty-five patients with hepatic metastases were examined with helical CT. The first imaging phase was initiated at 50 sec and the second 75 sec after the start of contrast material injection (3 ml/sec, 150 ml). Differences in lesion and liver attenuation were measured quantitatively. Four radiologists used a 5-point scale to assess lesion conspicuity subjectively. RESULTS Mean differences in enhancement between liver and lesion were 41 H during the first phase and 59 H for the second phase (p = .0001). Radiologists conspicuity score averaged 2.4 for lesions in the first phase versus 3.3 for lesions in the second phase (p = .0001). In 56 (88%) of 64 lesions, objective measurements showed greater enhancement of lesions during the later phase. Radiologists found 60 (94%) of 64 lesions to be more
Celera Genomics saw its share price take a small hike yesterday after inking a deal with Schering AG - soon to be merged with Bayer - for its cathepsin S inhibitor programme in autoimmune disease. It comes with potential milestones worth up to $360 million and double-digit royalties, on top of a $5 million upfront payment, half of which will be paid now and the remainder after the rights are transferred, which is forecast to be in the next four months. - News - PharmaTimes
Adaptive Contrast Agent Medical Imaging - System parameters for contrast agent medical imaging are conveniently set. A simplified contrast agent configuration is provided where an appropriate contrast agent detection technique and/or contrast agent imaging parameters are achieved consistently and more often then exists with current methods. Examination workflow is improved for contrast agent studies by offering one contrast agent imaging mode or configuration that is dynamically determined and optimized based on the users selected transmit level and/or a real-time measurement of the contrast agent signals. A simplified user interface provides one contrast agent imaging mode without a need to switch between multiple modes or contrast agent detection techniques and associated contrast agent imaging parameters. The contrast agent detection technique and imaging parameters are adjusting or selected based on changes in the transmit levels for contrast agent imaging. Either a single user input ...
Contrast-induced nephropathy (CIN) is a significant problem resulting from the use of iodine contrast agents in computed tomography (CT) scans and cath lab angiography. It can have a negative.... ...
Contrast media, also called contrast agents, are used to enhance the blood and perfusion in tissues.This includes iodine based contrast for on computed tomography (CT), gadolinium based agents for MRI and lipid bubble contrast agents used in ultrasound.
This report analyzes the worldwide markets for Imaging Agents in Millions of US$. The major product segments analyzed are Contrast Media (X-Ray, MRI, & Ultrasound), and Diagnostic Radiopharmaceuticals. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Middle East, and Latin America. Annual forecasts are provided for each region for the period of 2000 through 2015. The report profiles 67 companies including many key and niche players worldwide such as AMAG Pharmaceuticals Inc., Amersham Plc, Bayer Schering Pharma AG, Bayer HealthCare Pharmaceuticals, Bracco Group, E-Z-EM Inc., Covidien, Cytogen Corp., Daiichi Sankyo Company Limited, Eisai Co., Ltd, EPIX Pharmaceutical Inc., Guerbet Group, and Lantheus Medical Imaging. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources ...
TY - JOUR. T1 - Non-contrast-enhanced computerized tomography and analgesic-related kidney disease. T2 - Report of the National Analgesic Nephropathy Study. AU - Henrich, William L.. AU - Clark, Richard L.. AU - Kelly, Judith P.. AU - Buckalew, Vardaman M.. AU - Fenves, Andrew. AU - Finn, William F.. AU - Shapiro, Joseph I.. AU - Kimmel, Paul L.. AU - Eggers, Paul. AU - Agodoa, Larry E.. AU - Porter, George A.. AU - Shapiro, Samuel. AU - Toto, Robert. AU - Anderson, Theresa. AU - Cupples, L. Adrienne. AU - Kaufman, David W.. PY - 2006/5. Y1 - 2006/5. N2 - Previous studies suggested that the non-contrast-enhanced computerized tomography (CT) scan is a highly reliable tool for the diagnosis of analgesic-associated renal disease. However, this issue has not been addressed in the US population. A total of 221 incident patients with ESRD from different regions of the United States underwent a helical CT scan and detailed questioning about drug history. Specific renal anatomic criteria were developed ...
Contrast-enhanced CT studies are highly diagnostic and involve little physiological stress. To obtain the best results, protocols for contrast enhancement must take into consideration the patient...
This study was conducted to compare the effects of different doses of gadodiamide during serial MR imaging on rCBV maps. The double dose of gadodiamide injection (0.2 mmol/kg) was superior to the 0.1 mmol/kg dose in terms of CNR, image quality, contrast effect, sensitivity, and specificity. Even though the 0.3 mmol/kg dose was slightly better than the 0.2 mmol/kg dose with respect to CNR, image quality and contrast effects were less favorably rated, and sensitivity and specificity were also lower. These results are in agreement with preliminary results of testing doses of 0.1 and 0.2 mmol/kg (22, 29, 30).. The higher doses of gadodiamide (0.2 and 0.3 mmol/kg) gave superior results with respect to CNR. We hypothesize that the 0.1 mmol/kg dose was too small to induce a sufficient susceptibility effect with the sequences and field strength used. Possibly, a change in the injection protocol with bolus injection rates exceeding 5 mL/s would result in a more compact bolus formation and subsequently in ...
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Medical Radiology. Linköping University, Center for Medical Image Science and Visualization, CMIV.ORCID iD: 0000-0002-2167-2450 ...
Results: The CT dose index volume decreased by 23.68% and 23.57% and the dose length product dropped by 25.59% and 18.45% in the arterial and portal venous phases, respectively, in the experiment than control group. The contrast dose was reduced by 16.86% in the experiment group. In the 70keV+30% IR group, the noise of liver, pancreas and sacrospinal muscle were significantly (P,0.05) lower in both phases than the control group, and the score was higher than in the control group (P,0.05). In the 55keV+ 50% IR group, the arterial contrast-to-noise ratio and scores were significantly (P,0.05) higher in the arterial phase but the sacrospinal muscle noise was significantly (P,0.05) lower than in the control group. ...
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Kelm, B M, Müller, N, Menze, B H and Hamprecht, F A (2006). Bayesian Estimation of Smooth Parameter Maps for Dynamic Contrast-Enhanced MR Images with Block-ICM. Proc Computer Vision and Pattern Recognition Workshop (Mathematical Methods in Biomedical Image Analysis). IEEE Computer Society. 96-103 ...
Within the lipoprotein family, historically LDL has been most exploited as an imaging agent. The idea of HDL as an imaging agent is relatively new, and only a limited number of HDL-based nanoparticles for imaging have been reported. Even so, there are already examples of HDL imaging particles of very sophisticated design.. Our own work has focused primarily on the development of HDL-based contrast agent for the detection of macrophages in atherosclerotic plaques with MRI as well as with CT and optical techniques. To improve detectability and to allow a lower dose to be injected, several modifications have been introduced to enhance the contrast generating properties. For example, the nanocrystal HDL platform allows the inclusion of nanoparticulate diagnostically active materials. In addition, amphiphilic Gd chelates can be used that exhibit improved relaxivity (eg, by including a so-called q=2 MRI contrast agent as reported by Briley-Saebo et al69).. In addition to the potential imaging of the ...
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In the Global Contrast Media Injectors Industry Market Analysis & Forecast 2018-2023, the revenue is valued at USD XX million in 2017 and is expected to reach USD XX million by the end of 2023, growing at a CAGR of XX% between 2018 and 2023. The production is estimated at XX million in 2017 and is forecasted to reach XX million by the end of 2023, growing at a CAGR of XX% between 2018 and 2023.
The Global report entails the overall and all-encompassing study of the "Contrast Media Injector Market" with all its relevant factors that might have an influence…. ...
... by Ruth Dennis http://i.imgur.com/33EI1C8.png Pages: 38 slices Publisher: -- Edition: 2002, WSAVA, FECAVA, AVEPA Language: English
Free shipping and guaranteed authenticity on Design History Ink Spot / Pink Chiffon Contrast - Medium Tank Top Size 8 (M)This gorgeous, unique, elegant, sweeping Chiffon T...
Researchers of Vrije Universiteit Brussel developed a new type of fluorescent contrast liquid for use in cancer surgery. This allows the surgeon to carry out operations in a more precise and accurate way. Both patients survival rates and quality of life should improve significantly as a result of the new technique.
زمینه و هدف: استفاده از مادۀ حاجب در تصویربرداری، کلیه-ها را در معرض آسیب قرار داده که به آن نفروپاتی ناشی از کنتراست یاContrast-Induced Nephropathy (CIN) گفته می‌شود. این اصطلاح زمانی به-کار برده می‌شود که افزایش کراتینین سرم بیش از 25% از سطح پایه یا بیش از 5/0 میلی-گرم در دسی-لیتر طی 3-2 روز بعد از تجویز کنتراست، بدون حضور بیماری-های دیگر کلیوی رخ دهد. بروز CIN در جمعیت بزرگ‌سالانی که آنژیوگرافی قلبی شده-اند، حدود 20-10% است، ولی مطالعات در این زمینه در کودکان بسیار محدود است. هدف از این مطالعه بررسی بروز این عارضه در کودکان مبتلا به بیماری مادرزادی قلبی بود. روش بررسی: در این
Prevention centers around avoiding volume depletion. This has led to trials and practices using oral hydration, volume expansion with IV fluids and bicarbonate, and both holding and using diuretics. O... more
the abdominal aorta and its main vessels." - CEUS (11/19/2009): " Complete portal vein thrombosis extended to the ... with contrast medium, Abdominal MR with contrast medium, CEUS, Chest CAT scan with contrast medium, Esophagogastroduodenoscopy, Total .... ...
The browser does not support JavaScript. The calculations created using SpreadsheetConverter will not work. Please access the web page using another browser.. ...
At the recent AACR-NCI-EORTC meeting (October-November 2001) in Miami, FL, Pat Price from the University of Manchester, Manchester, United Kingdom (18), reviewed the most reliable methods to assess the efficacy of antiangiogenic compounds using either functional computed tomography, dynamic contrast-enhanced MRI, ultrasound, or 15O-positron emission tomography scanning techniques. Emphasis was on the complexity of the measurement and the need to validate these techniques as potential early surrogate end points for a variety of cancer treatments. The availability of an imaging tool combining either MRI, positron emission tomography, or ultrasound scanning with a biological readout system, which is able to correlate or even predict a successful tumor immune response, would greatly facilitate future clinical designs. Nevertheless, these are measurements of the "nonimmune" parameters. In immunotherapy it is important to be able to measure an "effective," tumor-specific immune response.. If the ...
Schering Corp. said that My-K Laboratories Inc. of Skokie agreed to a permanent injunction prohibiting My-K from making or selling products similar to Schering`s ``Afrin`` nasal decongestant. My-K
CT contrast is associated with many harms that we overlook in medicine. Might its cardiovascular effects be related to patients crashing in CT?
Contrast enhancement has an important role in image processing applications. Conventional contrast enhancement techniques either often fail to produce sati
Low-biofouling membrane: We aim at investigating the polymer/additives couples that would possibly lead to best low-biofouling properties. The preparation method is the blending method coupled to a phase inversion process. This technique does not involve any other unit operation in the membrane preparation process, compared to surface modification processes, and is believed to enhance hydration and low-biofouling properties of the whole membrane ...
Even in patients at low risk for contrast-induced nephropathy, the choice of contrast medium for CT scans can have a big impact on safety.
While there has been considerable interest in the development of imaging biomarkers for use in clinical trials, most DCE-MR imaging studies have focused on identifying correlates of vascularity and angiogenesis.41 This study identified an unexpected positive correlation between ve, a parameter thought to reflect extravascular extracellular space volume, and mitotic activity. No relationships were identified among the previously described DCE-MR imaging prognosticators, Ktrans and vp, and mitotic activity or between vascular patterns and DCE-MR imaging measures.. The parameter ve is often overlooked in DCE-MR imaging studies. In cerebral tumors, it has the potential to distinguish intra- from extra-axial tumors42,43 and exhibits increased values with increasing tumor grade.33,34,42,44 It has also demonstrated sensitivity in identifying changes in response to treatment with corticosteroids, with decreases in ve presumably reflecting a reduction in interstitial edema.45,46 In a study of vestibular ...
The purpose of this study is to see if dynamic contrast enhanced (DCE) MRI imaging makes it possible to distinguish benign conditions of the breast from
NBPA Dir of Security & Agent Administration ROBERT GADSON yesterday confirmed that RICH PAUL , longtime friend of Heat F LEBRON JAMES , has been certified by the NBPA to represent players in contract talks with clubs. Paul recently left CAA with James to start a new NBA player representation fir
In many clinical situations, contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) is the best option for achieving a timely and acc...
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Amersham Health is applying Big Pharma marketing and R&D strategies to the traditionally stodgy, highly price-sensitive field of diagnostic imaging contrast agents. It has been far more aggressive than competitors in working to make innovation the basis of competition. But some analysts question whether the company can maintain near-to-mid-term growth as it awaits results of its risky, long-term effort in molecular imaging.. ...
The AR analysis used the mean of the values for the 3 blinded readers. The 3 BRs evaluated the images from the unenhanced MRI in one session and the images from the combined unenhanced and gadobutrol-enhanced MRIs in another. Contrast enhancement was scored on a 4-point scale where 1 = no enhancement and 4 = excellent enhancement. Border delineation was scored on a 4-point scale where 1 = no or unclear delineation and 4 = excellent delineation. Internal morphology was scored on a 3-point scale where 1 = poorly visible and 3 = sufficiently visible ...
Objective. We aimed to determine whether contrast-enhanced ultrasonography can predict the effects of neoadjuvant chemotherapy on breast cancer.. Methods. The clinical responses of 63 consecutive patients with breast cancer (T1-4, N0-1, M0) to neoadjuvant chemotherapy between October 2012 and May 2015 were assessed using contrast-enhanced magnetic resonance imaging, positron emission tomography/computed tomography and contrast-enhanced ultrasonography. Perfusion parameters for contrast-enhanced ultrasonography were created from time-intensity curves based on enhancement intensity and temporal changes to objectively evaluate contrast-enhanced ultrasonography findings. The sensitivity, specificity and accuracy of contrast-enhanced ultrasonography, magnetic resonance imaging and positron emission tomography/computed tomography to predict a pathological complete response were compared after confirming the pathological findings of surgical specimens.. Results. Twenty-three (36.5%) of the 63 patients ...
Until recently, it was believed that MRI contrast agents were some of the safest solutions used on humans. Very few side effects and adverse reactions were reported and many of those issues were very mild. Then, in 2006 researchers discovered a plausible link between the use of Gadolinium based MRI contrast agents and the development of a debilitating condition called Nephrogenic Systemic Fibrosis. The condition reportedly developed when patients with impaired renal function received an injection of a Gadolinium based MRI contrast agent prior to an MRI procedure. Out of the cases reviewed by the US Food and Drug Administration, all patients had impaired renal function or renal failure and all received a Gadolinium based MRI contrast agent injection prior an MRI. The cases all developed within two days to eighteen months of receiving the initial injection.. The first cases of Nephrogenic Systemic Fibrosis were discovered in 1997 and the first medical references about the condition were written in ...
How is T1-weighted, gadolinium-enhanced magnetic resonance Imaging abbreviated? T1-MRI stands for T1-weighted, gadolinium-enhanced magnetic resonance Imaging. T1-MRI is defined as T1-weighted, gadolinium-enhanced magnetic resonance Imaging rarely.
The aim of this study was to compare the enhancement pattern of intrahepatic cholangiocarcinoma (ICC) on contrast-enhanced ultrasound (CEUS) with that on contrast-enhanced computed tomography (CECT). 40 pathologically proven ICC lesions in 40 patients were evaluated retrospectively with both CEUS and CECT. The enhancement level and pattern in the dynamic phases on both CEUS and CECT were analysed. The diagnostic results of CEUS and CECT before pathological examination were also recorded. During arterial phases, the number of lesions that appeared as (i) peripheral irregular rim-like hyperenhancement, (ii) diffuse heterogeneous hyperenhancement, (iii) diffuse homogeneous hyperenhancement and (iv) diffuse heterogeneous hypoenhancement were 19 (47.5%), 9 (22.5%), 5 (12.5%) and 7 (17.5%), respectively, on CEUS, and 22 (55.0%), 3 (7.5%), 2 (5.0%) and 13 (32.5%), respectively, on CECT (p = 0.125). In the portal phase, the number of lesions showing hyperenhancement and hypoenhancement were 1 (2.5%) and ...
RESULTS. There were 27 patients (14 male, 13 female) with a mean age of 62 (range, 44-77) years. There were 10 patients with renal transplants; their native renal arteries were not evaluated. Each of the two experienced interventional and body magnetic resonance radiologists, who were blinded to the results, reviewed the digital subtraction angiography and magnetic resonance angiography images respectively. Digital subtraction angiography was used as the standard of reference. A total of 39 renal arteries from these 27 patients were evaluated. One of the arteries was previously stented and could not be assessed with magnetic resonance angiography due to severe artefacts. Of the remaining 38 renal arteries, two were graded as normal, seven as having mild stenosis (=50% but =75%). Magnetic resonance angiography and digital subtraction angiography were concordant in 89% of the arteries; magnetic resonance angiography overestimated the degree of stenosis in 8% and underestimated it in 3% of them. In ...
We demonstrate that fatty acid modified iron oxide prolonged retention of the contrast agent in the polymer matrix during degradative release of drug. Antibody-fatty acid surface modification facilitated cellular targeting and subsequent internalization in cells while inducing clustering of encapsulated fatty-acid modified superparamagnetic iron oxide during particle formulation. This induced clustered confinement led to an aggregation within the nanoparticle and, hence, higher transverse relaxivity, r2, (294 mM−1 s−1) compared with nanoparticles without fatty-acid ligands (160 mM−1 s−1) and higher than commercially available superparamagnetic iron oxide nanoparticles (89 mM−1 s−1). ...
Page contains details about c-erbB2 antisense probe labeled with superparamagnetic iron oxide nanoparticles . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
In recent years, nanotechnology has emerged as one of the most promising fields for biomedical applications and healthcare. The use of nanoparticles has earned much attention due to their small size, high surface area to volume ratio along with surface charge, and their optical and semiconducting properties. Superparamagnetic iron oxide nanoparticles (SPIONs), which show superparmagnetism, have been reported to be reliable and safe for many biological applications.In the present study, 10nm SPION were loaded with anticancer drug, Docetaxel. Docetaxel conjugation to SPION was confirmed by FTIR, UV-vis spectroscopy and gel electrophoresis. SPIONs uptake by cells was investigated using Prussian blue dye staining.In vitro drug release was studied which showed 55% drug release in 24 h. Drug loaded SPION were then tested on Mammary tumor cells (4T1) and showed 40% cell viability with 0.1M Docetaxel conjugated to SPION. Our results shows that Docetaxel-SPIONs can reduce the amount of required anticancer drug
Contrast echocardiography was used before cardiac catheterisation in 37 patients with atrial septal defect and a left-to-right shunt and in 18 patients with a raised right atrial and ventricular pressure to assess the contrast echo effect in the inferior vena cava. Using two dimensional contrast apical echocardiography we found a negative contrast echo effect within the right atrium in many but not all patients with atrial defect. Contrast echoes entering the inferior vena cava during presystole or early to mid-diastole were detected in patients with heart disease causing raised right atrial and ventricular pressures and also in all patients with atrial septal defect. No contrast echo effect in the inferior vena cava was detected in 10 normal subjects. The sensitivity of this contrast pattern in the inferior vena cava in diagnosing atrial septal defect was 100%. When other conditions causing raised right atrial pressure were excluded, the specificity and predictive accuracy were 100% for both. ...

The iodinated radiographic contrast medium iohexol mimics the vasodilator effect seen with small increases in extracellular K+...The iodinated radiographic contrast medium iohexol mimics the vasodilator effect seen with small increases in extracellular K+...

The iodinated radiographic contrast medium iohexol mimics the vasodilator effect seen with small increases in extracellular K+ ... Purpose: To investigate whether iodinated radiographic contrast media (IRCM) mimic the hyperpolarizing and vasodilator effects ... Barium, Endothelium, Hyperpolarization, Iodinated radiographic contrast media, Iohexol, Ouabain, Potassium, Vascular smooth ...
more infohttp://liu.diva-portal.org/smash/record.jsf?pid=diva2:271039

Are marketers spending wisely on social media? - Are marketers spending wisely on social media? | The Economic TimesAre marketers spending wisely on social media? - Are marketers spending wisely on social media? | The Economic Times

New research commissioned by Pitney Bowes Software looks at the behaviours and attitudes towards social media from both a ... Social media is everywhere and marketers are planning to take full advantage by pledging more budget than ever to the plethora ... By contrast, after Facebook, consumers spend most of their time on YouTube - rated only fifth in the pecking order by marketers ... Are marketers spending wisely on social media?. Social media is everywhere and marketers are planning to take full advantage by ...
more infohttps://economictimes.indiatimes.com/advertising-marketing/are-marketers-spending-wisely-on-social-media/slideshow/17956181.cms

ms-high-contrast media feature (Internet Explorer)ms-high-contrast media feature (Internet Explorer)

media screen and (-ms-high-contrast: active) { /* All high contrast styling rules */ } @media screen and (-ms-high-contrast: ... ms-high-contrast media feature. Describes whether the application is being displayed in high contrast mode, and with what color ... The -ms-high-contrast media feature works with the -ms-high-contrast-adjust property. ... The -ms-high-contrast media feature was introduced in Windows 8.. Examples. The following declarations will match applications ...
more infohttps://msdn.microsoft.com/library/hh771830

Pulmonary Effects of Iodine-Based Contrast Media | SpringerLinkPulmonary Effects of Iodine-Based Contrast Media | SpringerLink

Water soluble iodine-based contrast media may increase the airway resistance, the pulmonary vascular resistance (PVR), and also ... Morcos S.K. (2014) Pulmonary Effects of Iodine-Based Contrast Media. In: Thomsen H., Webb J. (eds) Contrast Media. Medical ... Central venous injection of large amounts of contrast media-advantages of low osmolar contrast medium in experimentally induced ... Morcos SK (2003) Effects of radiographic contrast media on the lung. Br J Radiol 76:290-295PubMedCrossRefGoogle Scholar ...
more infohttps://link.springer.com/chapter/10.1007/174_2013_893

Contrast Media Use in Pediatrics: Safety Issues | SpringerLinkContrast Media Use in Pediatrics: Safety Issues | SpringerLink

Contrast media appear to be just as safe in children as they are in adults. The risk factors are the same and the same ... Riccabona M. (2014) Contrast Media Use in Pediatrics: Safety Issues. In: Thomsen H., Webb J. (eds) Contrast Media. Medical ... ACR Manual on Contrast Media, version 8 (2012a) Contrast media in children, p 47-52 and p 79 http://www.acr.org/~/media/ACR/ ... Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Media Safety Committee guidelines. Eur ...
more infohttps://link.springer.com/chapter/10.1007/174_2013_901

Patent US20090275829 - Contrast media injector kit - Google PatentsPatent US20090275829 - Contrast media injector kit - Google Patents

... an inlet port for connection with a container of a contrast agent or saline and for receiving the contrast agent or saline; and ... The general strategy in designing any contrast media relies upon exploiting the differences in contrast media distribution so ... An ideal contrast medium has innumerable criteria to meet before it is suitable for administration in the body. Since contrast ... With a new setup for each patient the unused contrast is discarded. This proves to be very costly as the contrast media is very ...
more infohttp://www.google.ca/patents/US20090275829

Contrast Media & Molecular Imaging - An Open Access JournalContrast Media & Molecular Imaging - An Open Access Journal

An exciting journal in the area of contrast agents and molecular imaging, covering all areas of imaging technologies with a ... Contrast Media articles will cover innovative work on all aspects of this field, such as the development of more sensitive ... Contrast Media & Molecular Imaging is included in many leading abstracting and indexing databases. For a complete list, click ... Contrast Media & Molecular Imaging is archived in Portico, which provides permanent archiving for electronic scholarly journals ...
more infohttps://www.hindawi.com/journals/cmmi/

Safety of magnetic resonance contrast media.  - PubMed - NCBISafety of magnetic resonance contrast media. - PubMed - NCBI

Safety of magnetic resonance contrast media.. Runge VM1.. Author information. 1. Department of Radiology, Scott and White ... Intravenous contrast media, specifically the gadolinium chelates, are well accepted for use in the clinical practice of ... the nephrotoxicity found with iodinated contrast media. Minor adverse reactions, including nausea and hives, occur in a low ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/11687717?dopt=Abstract

Contrast Media & Molecular Imaging - An Open Access JournalContrast Media & Molecular Imaging - An Open Access Journal

An exciting journal in the area of contrast agents and molecular imaging, covering all areas of imaging technologies with a ... To receive news and publication updates for Contrast Media & Molecular Imaging, enter your email address in the box below. ... and reproduction in any medium, provided that the original work is properly cited. ...
more infohttps://www.hindawi.com/journals/cmmi/guidelines/

Contrast Medium Reactions: Practice EssentialsContrast Medium Reactions: Practice Essentials

... organic radiographic iodinated contrast media (ICM) have been among the most commonly prescribed drugs in the history of modern ... encoded search term (Contrast Medium Reactions) and Contrast Medium Reactions What to Read Next on Medscape. Related Conditions ... High-osmolality contrast media. High-osmolality contrast media consist of a tri-iodinated benzene ring with 2 organic side ... Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media. ...
more infohttps://emedicine.medscape.com/article/422855-overview

Contrast-media induced nephropathy in patients undergoing coronary angiography.  - PubMed - NCBIContrast-media induced nephropathy in patients undergoing coronary angiography. - PubMed - NCBI

Contrast-media induced nephropathy in patients undergoing coronary angiography.. Gomes VO1, Blaya P, Poli de Figueiredo CE, ... Contrast-medium induced nephropathy (CIN) in patients undergoing cardiac catheterization has an extremely variable incidence, ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/12777666?dopt=Abstract

Contrast Media Injectors Market Maintain Its Fastest Growing... - TMRContrast Media Injectors Market Maintain Its Fastest Growing... - TMR

Global Contrast Media Injectors Market was valued at USD 630.1 million in 2013 and is estimated to reach a market worth USD ... Contrast media injectors are systems that inject contrast media into the body in order to enhance the quality of medical ... associated with the usage of contrast media or agents are also projected to negatively impact the application of contrast media ... Increasing Need for Contrast Scanning to Stimulate Demand for Contrast Media Injectors ...
more infohttp://www.mynewsdesk.com/us/pressreleases/contrast-media-injectors-market-maintain-its-fastest-growing-economy-title-till-2020-1746021

United States Contrast Media Injectors Market Analysis, Size,... - Knowledge HubUnited States Contrast Media Injectors Market Analysis, Size,... - Knowledge Hub

The Report United States Contrast Media Injectors Market Outlook to 2022 provides information on pricing, market analysis, ... medical sciencechemicalsequipmentcontrast mediainjectorsmediamedia injectorscontrastcontrast media injectorscontrast media ... 3 Contrast Media Injectors Market, United States 6. 3.1 Contrast Media Injectors Market, United States, Revenue ($m), 2008-2015 ... "United States Contrast Media Injectors Market Outlook to 2022", provides key market data on the United States Contrast Media ...
more infohttp://www.mynewsdesk.com/us/pressreleases/united-states-contrast-media-injectors-market-analysis-size-share-trends-estimates-and-forecasts-to-2022-1774915

Contrast Media in Magnetic Resonance Imaging by Val M. Runge, Hardcover | Barnes & Noble®Contrast Media in Magnetic Resonance Imaging by Val M. Runge, Hardcover | Barnes & Noble®

The Hardcover of the Contrast Media in Magnetic Resonance Imaging by Val M. Runge at Barnes & Noble. FREE Shipping on $25.0 or ...
more infohttps://www.barnesandnoble.com/w/contrast-media-in-magnetic-resonance-imaging-val-m-runge/1000987831

Computational Laser Speckle Contrast Imaging in Endoscopic System - MIT Media LabComputational Laser Speckle Contrast Imaging in Endoscopic System - MIT Media Lab

... using laser speckle contrast imaging. Computational imaging is used to reject sub-surface scattering and eliminates erroneous ...
more infohttps://www.media.mit.edu/publications/computational-laser-speckle-contrast-imaging-in-endoscopic-system/

Contrasting Cultures - OReilly MediaContrasting Cultures - O'Reilly Media

This chapter from Transnational Leadership Development introduces leaders to the contrasts that exist between those raised in ... Contrasting Cultures. I-Centric and We-Centric. By Beth D., Ph. GELLER ... 2017 OReilly Media, Inc. All trademarks and registered trademarks appearing on oreilly.com are the property of their ... This chapter from Transnational Leadership Development introduces leaders to the contrasts that exist between those raised in ...
more infohttp://shop.oreilly.com/product/9780814432570.do

Contrast Media & Molecular Imaging - Volume 1, Issue 2 - March/April 2006 - Wiley Online LibraryContrast Media & Molecular Imaging - Volume 1, Issue 2 - March/April 2006 - Wiley Online Library

CMR 2005: 5.02: Nephrotoxicity of iodine contrast media, iso-osmolar to plasma, in comparison with gadolinium contrast media ... Current Awareness in Contrast Media and Molecular Imaging (pages 93-100). Version of Record online: 19 APR 2006 , DOI: 10.1002/ ... International Contrast Media Research Symposium-Program (pages 49-51). Version of Record online: 19 APR 2006 , DOI: 10.1002/ ... CMR 2005: 14.04: Oral manganese as contrast medium in detecting liver metastases with MR imaging at 1.5 and 3 T (pages 90-91). ...
more infohttp://onlinelibrary.wiley.com/doi/10.1002/cmmi.v1:2/issuetoc

Usage of Contrast Media | ISRRTUsage of Contrast Media | ISRRT

ISRRTs Position Statment Supply and Administration of Contrast Agents - including Oral and Intravascular Administration to ... Usage of Contrast Media. ISRRTs Position Statment. Supply and Administration of Contrast Agents - including Oral and ... media/ACR/Documents/PDF/QualitySafety/Resources/Contrast%20Manual/2015_Contrast_Media.pdf ... The ISRRT Board promotes the scope of practice for the administration of oral and intravenous contrast agents by Radiographers ...
more infohttps://www.isrrt.org/usage-contrast-media

Photoacoustic tomography: fundamentals, advances and prospects - Yao - 2011 - Contrast Media & Molecular Imaging - Wiley Online...Photoacoustic tomography: fundamentals, advances and prospects - Yao - 2011 - Contrast Media & Molecular Imaging - Wiley Online...

This article is published in Contrast Media and Molecular Imaging as part of the special issue on Photoacoustic Imaging, edited ... Previous article in issue: Emerging contrast agents for photoacoustic imaging Previous article in issue: Emerging contrast ... Because of this high scalability and its unique optical absorption contrast, PAT is capable of performing anatomical, ... Next article in issue: Advanced contrast nanoagents for photoacoustic molecular imaging, cytometry, blood test and photothermal ...
more infohttp://onlinelibrary.wiley.com/doi/10.1002/cmmi.443/abstract

contrast media Protocols and Video...'contrast media' Protocols and Video...

... contrast media include Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance ... MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent, Magnetically-Assisted ... Contrast Media: Substances used to allow enhanced visualization of tissues. .article_summary_container button.expand{ display: ... MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent. Xueming Wu1, Daniel ...
more infohttps://www.jove.com/keyword/contrast+media

Contrast Media | Springer for Research & DevelopmentContrast Media | Springer for Research & Development

General principles of X-ray contrast media 10 13 Structure and properties of X-ray contrast media Barium sulfate 13 ... Contrast media in diagnostic imaging 8 Visualization of functions 8 • Morphology 9 • ... Nonionic contrast media 16 Osmolality and side effects caused by hypertonicity 18 Ionic contrast media 20 21 Contrast media for ... of X-ray contrast media 10 13 Structure and properties of X-ray contrast media Barium sulfate 13 Water-soluble contrast media ...
more infohttps://rd.springer.com/book/10.1007%2F978-3-642-85995-3

X-Ray Contrast Media, Iodinated - DrugBankX-Ray Contrast Media, Iodinated - DrugBank

For use as a contrast medium [L1597].. DB09347. Acetrizoic acid. Acetrizoic acid indication was to be used as a contrast agent ... Iophendylate is used as a contrast agent to locate spinal tumors.. DB01249. Iodixanol. Iodixanol is a contrast agent during ... The use of contrast agents will provoke a contrast enhancement or opacification and it will improve the differentiation of ... Iopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial ...
more infohttps://www.drugbank.ca/categories/DBCAT002273

Buoyancy of gallstones in varying concentrations of contrast media.Buoyancy of gallstones in varying concentrations of contrast media.

Gallstones from 100 patients were tested for buoyancy in four concentrations of contrast materials commonly used in the biliary ... Contrast Media / administration & dosage*. Diatrizoate Meglumine / administration & dosage. Humans. Specific Gravity. Chemical ... Gallstones from 100 patients were tested for buoyancy in four concentrations of contrast materials commonly used in the biliary ... substitution of the most dilute contrast material visible and the use of very low kilovoltage should help in one-fourth of ...
more infohttp://www.biomedsearch.com/nih/Buoyancy-gallstones-in-varying-concentrations/6610336.html

Vasomotor effects of iodinated contrast media: just side effects?Vasomotor effects of iodinated contrast media: just side effects?

All classes of iodinated radiographic contrast media are vasoactive, with iso-osmolar dimers inducing the smallest changes in ... Routinely used iodinated contrast media have complex vasomotor effects on several arterial districts. ... Routinely used iodinated contrast media have complex vasomotor effects on several arterial districts. All classes of iodinated ... Contrast Media / adverse effects*, chemistry. Coronary Artery Disease / complications, physiopathology. Coronary Circulation / ...
more infohttp://www.biomedsearch.com/nih/Vasomotor-effects-iodinated-contrast-media/15320478.html

Chip Kelly, Herm Edwards and the media: Different styles, same goal, one fascinating contrastChip Kelly, Herm Edwards and the media: Different styles, same goal, one fascinating contrast

... which are reflected in contrasting approaches to the media. Neither view is right or wrong. But the differing approaches help ... Chip Kelly, Herm Edwards and the media: Different styles, same goal, one fascinating contrast. ... The contrast, though, is fascinating. Why we need your support: Like so many other providers of local journalism across the ... More than half have been arranged through official channels, but many are simply the result of Edwards years in the media. He ...
more infohttp://www.santacruzsentinel.com/sports/20180313/chip-kelly-herm-edwards-and-the-media-different-styles-same-goal-one-fascinating-contrast
  • Benyon HLC, Walport MJ, Dawson P (1994) Vascular endothelial injury by intravascular contrast agents. (springer.com)
  • Radiographers, Medical Radiation Technologists and Radiation Therapists following their training will obtain a thorough understanding and knowledge of the identification, preparation, calculation, documentation, administration and patient monitoring related to the administration of oral and intravascular contrast agents. (isrrt.org)
  • 2 . The integrated contrast injector kit of claim 1 , wherein the first input arm of the Y-tubing comprises a first back check valve and the second input arm of the Y-tubing comprises a second back check valve. (google.ca)
  • 3 . The integrated contrast injector kit of claim 2 , wherein the first and second back check valves are located at the beginning of the first and second input arms and each is integrally connected with the output port of the first and second fluid control valves. (google.ca)
  • 5 . The integrated contrast injector kit of claim 4 , wherein the back check valve is located at the end of the output arm of the Y-tubing and is for releasable connection with the patient line. (google.ca)
  • 6 . The integrated contrast injector kit of claim 1 , wherein the inlet port of at least one of the first and second fluid control valves is integrally connected to tubing that ends in a vented spike that is for releasable connection with the contrast agent or saline container. (google.ca)
  • 7 . The integrated contrast injector kit of claim 1 , wherein the syringe port of at least one of the first and second fluid control valves are integrally connected with tubing that ends in a female luer port that is for connection with the syringe. (google.ca)
  • 8 . The integrated contrast injector kit of claim 1 , wherein the syringe port or the tubing extending therefrom is for releasable connection with the syringe. (google.ca)
  • 9 . The integrated contrast injector kit of claim 1 , further comprising the syringe integrally connected to the syringe port, or tubing extending therefrom, of at least one of the first and second fluid control valves. (google.ca)
  • 10 . The integrated contrast injector kit of claim 1 , wherein the fluid control valve is a 3-port manual or automatic fluid control valve. (google.ca)
  • 11 . The integrated contrast injector kit of claim 1 , wherein the fluid control valve is an automatic dual check valve. (google.ca)
  • 12 . The integrated contrast injector kit of claim 1 , wherein the fluid control valve is a stopcock. (google.ca)
  • 13 . The integrated contrast injector kit of claim 1 , wherein integrally connected components are bonded using a medical grade solvent and/or using a welding technique. (google.ca)
  • CT contrast injectors will remain the most preferred injector across the world throughout the forecast period, states the report. (mynewsdesk.com)
  • A contrast medium injector for injecting a patient with contrast medium for a CT scan is programmed to provide an injection protocol that is a representation of an ideally defined exponential curve with an initial injection rate decaying at an exponential rate. (google.ca)
  • Use of saline with this innovative contrast medium injector allows multi-dosing from a saline container. (prnewswire.com)
  • This report focuses on the Contrast Media Injector in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. (rnrmarketresearch.com)
  • There are 15 Chapters to deeply display the global Contrast Media Injector market. (rnrmarketresearch.com)
  • Clariscan is a gadolinium-based contrast agent (GBCA) designed to support effective visualisation of abnormalities in the brain, spine and associated tissues, and will be provided alongside GE Healthcare's comprehensive support services and solutions to healthcare practitioners worldwide. (businesswire.com)
  • CMC Contrast AB (Sweden), Daiichi Sankyo (Japan), Bayer HealthCare (Germany), GE Healthcare (U.S.), Guerbet Group (France), Bracco Imaging S.p.A. (Italy) in 2015. (emailwire.com)
  • However, a few pivotal factors affecting the growth of this market are major economies of the world undergoing healthcare reforms, thereby affecting contrast media sales and the economic slowdown restricting the overall growth of this market. (prnewswire.co.uk)
  • The "Global Contrast Media/Agent Market Analysis to 2025" is a specialized and in-depth study of the healthcare industry with a focused global market trend. (medgadget.com)
  • Owing to technical advancements, the burgeoning healthcare industry is expected to largely influence the contrast media market. (medgadget.com)
  • The contrast media market in the Asia Pacific region, led by the rapidly proliferating healthcare sector and developing economy, has emerged as a promising market, globally. (medgadget.com)
  • The rapidly growing healthcare industry and emerging economies like India, Japan, and China in the Asia Pacific region, a huge population, and increase in awareness towards benefits of contrast media are market dynamics expected to drive the regional market growth. (medgadget.com)
  • High-osmolality contrast media consist of a tri-iodinated benzene ring with 2 organic side chains and a carboxyl group. (medscape.com)
  • The osmolality is related to some of the adverse events of these contrast media. (medscape.com)
  • It is important to obtain a detailed allergic history, e.g., which contrast agent was used, nonionic versus ionic, high-osmolality versus low-osmolality, procedure, route of administration, the nature of the reaction, and the treatment for the reaction. (asahq.org)
  • Patients were matched for age (± 5 y) and sex, type and osmolality of contrast medium, and date (± 4 d) of procedure. (annals.org)
  • In our view, Figures 1E ⇓ and 1F ⇓ of the above-mentioned article not only show leptomeningeal contrast enhancement but also indicate extravasation of contrast medium into the cerebrospinal fluid (CSF) space. (ahajournals.org)
  • North America Contrast Media Market is worth USD 1.51 Billion in 2016 and estimated to grow at a CAGR of 5.5%, to reach USD 1.97 billion by 2021. (emailwire.com)
  • The North America Contrast Media market is rising at an exceptionally quick speed. (emailwire.com)
  • Lantheus Medical Imaging (U.S.), nanoPET Pharma GmbH (Germany), and Subhra Pharma Private Limited (India).are the leaders in the North America Contrast Media market. (emailwire.com)
  • Based on the region, the contrast media market is segmented into Asia Pacific, North America, Europe, and the Rest-of-the-World (RoW). (medgadget.com)
  • Chapters on the topics of nephrogenic systemic fibrosis and the administration of contrast media to pregnant or potentially pregnant patients have also been updated. (appliedradiology.com)
  • Laude EA, Emery CJ, Suvarna SK, Morcos SK (1999) The effect of antihistamine, endothelin antagonist and corticosteroid prophylaxis on contrast media induced bronchospasm. (springer.com)
  • The patient was reported to be allergic to contrast media. (asahq.org)
  • You should not receive it if you had an allergic reaction to any contrast dye. (baptistjax.com)
  • We found that atherosclerosis has an impact on the type of the contrast-induced coronary vasomotor reaction. (biomedsearch.com)
  • These findings have potential clinical implications, since the analysis of contrast-induced coronary vasomotion might result in a new test capable of evaluating vascular functional integrity. (biomedsearch.com)
  • This device is not intended for injection of contrast media for coronary arteriography, or for any other use for which the device is not indicated. (prnewswire.com)
  • Apart from this, the rising incidence of cancer, hemorrhage, complex fractures, cardiovascular disorders, and bone trauma are also projected to increase the need for contrast scanning to identify the tissues that differ in physical density, leading to a surge in the demand for contrast media injectors in the near future. (mynewsdesk.com)
  • The primary endpoint was the incidence of contrast-medium-induced kidney injury, defined as an increase of serum creatinine ≥ 25 % and/or ≥ 0.5 mg/dL above baseline at 48 hours after contrast-medium exposure. (ahajournals.org)
  • However, the microbubble contrast media segment is expected to grow at the highest CAGR during the forecast period. (marketsandmarkets.com)
  • MRFR's regional analysis of the Contrast Media Market gives a holistic approach towards the demographic progress of the market in the forecast years. (medgadget.com)
  • While this region presently dominates the market for contrast media injectors, analysts estimate the APAC region to show the highest growth during the forecast period as a result of its large population base. (rnrmarketresearch.com)
  • Dawson P, Harrison MJ, Weisblatt E (1983b) Effects of contrast media on red cell filterability and morphology. (springer.com)
  • Using species of contrasting taxonomy, morphology and physiology ( E. globulus and E. cladocalyx ), this study combines physiological characterizations with 'second-generation' sequencing to identify key genes involved in eucalypt responses to medium-term water limitation. (biomedcentral.com)
  • The most common contrast reaction is hives, which typically present as raised red wheels that may or may not be associated with pruritus. (appliedradiology.com)
  • The gadolinium chelates are considered to be very safe and lack (in intravenous use) the nephrotoxicity found with iodinated contrast media. (nih.gov)
  • Compared with saline, intravenous SB pretreatment significantly attenuated elevations in serum creatinine and the histological changes of renal tubular injuries, reduced the number of apoptosis-positive tubular cells, activated Nrf2, and lowered the levels of renal oxidative stress induced by iodinated contrast media. (pubmedcentralcanada.ca)
  • Visualization of intravenously administered contrast material in the CSF on fluid-attenuated inversion-recovery MR images: an in vitro and animal-model investigation. (ahajournals.org)
  • Barium sulfate forms the basis for a range of contrast media used in fluoroscopic examinations of the gastrointestinal tract . (radiopaedia.org)
  • The studies were restricted to examinations with intravenous application of contrast media A total of 352, 817 cases were collected. (nii.ac.jp)
  • To receive news and publication updates for Contrast Media & Molecular Imaging, enter your email address in the box below. (hindawi.com)
  • Contrast Media & Molecular Imaging (CMMI) provides an international forum for the expeditious publication of research articles, reviews, clinical studies, and letters to the editors in the booming areas of contrast media & molecular imaging. (hindawi.com)
  • Contrast Media & Molecular Imaging is archived in Portico , which provides permanent archiving for electronic scholarly journals, as well as via the LOCKSS initiative. (hindawi.com)
  • Contrast Media & Molecular Imaging is included in many leading abstracting and indexing databases. (hindawi.com)
  • Contrast Media & Molecular Imaging is a bimonthly peer-reviewed scientific journal published by John Wiley & Sons since 2006. (wikipedia.org)
  • This article is published in Contrast Media and Molecular Imaging as part of the special issue on Photoacoustic Imaging, edited by Dr. Gregory Lanza, Department of Medicine, Washington University Medical Hospital. (wiley.com)
  • Because of this high scalability and its unique optical absorption contrast, PAT is capable of performing anatomical, functional, molecular and fluid-dynamic imaging at various system levels, and is playing an increasingly important role in fundamental biological research and clinical practice. (wiley.com)
  • Contrast media of high and low molecular weights in the detection of recurrent herniated disks. (ajnr.org)
  • CONCLUSION Greater contrast is achieved between scar and recurrent herniated disk with a higher-molecular-weight contrast medium than with one of lower molecular weight. (ajnr.org)
  • The difference between the high- and low-molecular-weight contrast media increases with maturation of the scar tissue. (ajnr.org)
  • Gallstones from 100 patients were tested for buoyancy in four concentrations of contrast materials commonly used in the biliary tree. (biomedsearch.com)
  • It is important that radiologists are able to make a contrast media selection dependent on the needs of individual patients. (businesswire.com)
  • Demand for contrast media has significantly increased over the past decade due to rapid procedural advancements in MR imaging, elevating the importance of uninterrupted and sustainable product supply, as well as meeting the individual needs of patients undergoing diagnostic procedures. (businesswire.com)
  • GE contrast media products are used in more than 70 million procedures per year, equivalent to injection in two patients per second. (businesswire.com)
  • Increase in medical tourism, rise in the number of cancer patients and patients suffering from chronic disorders, and market players likely to deliver cost-competitive contrast media products are factors which are predicted to fuel the regional market growth. (medgadget.com)
  • 3 During the last 10 years we have found extravasation of contrast medium into the CSF space in 11 patients, who suffered from cardiovascular and cerebrovascular arteriosclerosis often associated with severe hypoxemic brain damage (Figures 1 ⇓ and 2). (ahajournals.org)
  • Of these patients, 188 were found to have brain metastases, and it is estimated that for this subgroup prophylactic diazepam reduces the risk of contrast-associated seizure by a factor of 0.26. (ajnr.org)
  • Out of 10,472 contrast-enhanced CTs performed, 3,945 carried out on 1,878 patients were considered for the study. (biomedcentral.com)
  • In order to determine the risk/benefit ratio on the time of evaluation of the disease and to evaluate if the risk may be time-dependent, we analysed the time elapsing between the contrast-enhanced CT scan, the most recent chemotherapy administration and the onset time of the ICM-related ARs in a consecutive cohort of cancer patients. (biomedcentral.com)
  • We provide targeted screening questions that can help to identify high-risk pediatric patients for both iodine-based and gadolinium-based intravenous contrast media administration. (springermedizin.de)