Contraceptives, Oral
Contraceptives, Oral, Combined
Contraceptives, Oral, Hormonal
Contraceptive Agents, Female
Contraceptives, Oral, Synthetic
Contraceptive Devices
Contraception
Contraceptive Agents, Male
Family Planning Services
Ethinyl Estradiol
Desogestrel
Norgestrel
Levonorgestrel
Contraceptives, Postcoital
Mestranol
Norethindrone
Pregnancy, Unplanned
Sterilization, Reproductive
Medroxyprogesterone Acetate
Spermatocidal Agents
Contraception, Postcoital
Intrauterine Devices, Copper
Menstruation
Norethynodrel
Ethynodiol Diacetate
Pregnancy
Abortion, Induced
Contraception, Immunologic
Norpregnenes
Ethinyl Estradiol-Norgestrel Combination
Progestins
Contraceptives, Oral, Sequential
Contraceptives, Postcoital, Hormonal
Sterilization, Tubal
Androstenes
Menstrual Cycle
Progesterone Congeners
Parity
Health Knowledge, Attitudes, Practice
Megestrol
Contraceptives, Postcoital, Synthetic
Drug Implants
Sex Education
Spermatogenesis-Blocking Agents
Ovulation Inhibition
Medroxyprogesterone
Fertility
Condoms
Norpregnadienes
Transdermal Patch
Ethisterone
Uterine Hemorrhage
Estradiol Congeners
Metrorrhagia
Risk Factors
Estrogens
Nonoxynol
Abortion, Legal
Reproductive Health Services
Age Factors
Marriage
Case-Control Studies
Reproductive History
Questionnaires
Coitus Interruptus
Logistic Models
Chlormadinone Acetate
Socioeconomic Factors
Family Planning Policy
Norprogesterones
Vasectomy
Cross-Sectional Studies
Delayed-Action Preparations
Natural Family Planning Methods
Thromboembolism
Reproductive Medicine
Women's Health Services
Menopause
Choice Behavior
Cohort Studies
Acne Vulgaris
Health Services Accessibility
Drug Interactions
Odds Ratio
Pyridoxine
Ethiopia
Risk
Premenopause
Marital Status
Indians, Central American
Endometrium
Ambulatory Care Facilities
Spermatozoa
Antispermatogenic Agents
Administration, Cutaneous
Hormone Replacement Therapy
Cyproterone Acetate
Gonadal Steroid Hormones
Health Surveys
Interviews as Topic
Vaginal Creams, Foams, and Jellies
Prospective Studies
Estrogen Replacement Therapy
Contraception, Barrier
Danazol
Nandrolone
Data Collection
Cervix Uteri
Abnormalities, Drug-Induced
Population Control
Progesterone
Uterine Perforation
Spermatogenesis
Mifepristone
Gynecology
Pregnanediol
Megaloblasts
Pregnancy Rate
Nigeria
Ovarian Neoplasms
Follicular Phase
Intrauterine Device Migration
Administration, Intravaginal
Student Health Services
Rwanda
Estradiol
Attitude
Vaginal Smears
Factor V
Multivariate Analysis
Paternalism
Premenstrual Syndrome
Developing Countries
Luteal Phase
Zambia
Libido
Madagascar
Sex
Confidence Intervals
Venous Thromboembolism
Pelvic Inflammatory Disease
Injections, Intramuscular
Gossypol
Risk Assessment
Department of health changes advice on third generation pills.(1/254)
(+info)Altered reflex control of cutaneous circulation by female sex steroids is independent of prostaglandins. (2/254)
We tested the hypothesis that the shift in the cutaneous vasodilator response to hyperthermia seen with elevated female reproductive hormones is a prostaglandin-dependent resetting of thermoregulation to higher internal temperatures, similar to that seen in the febrile response to bacterial infection. Using water-perfused suits to control body temperature, we conducted heat stress experiments in resting women under conditions of low and high progesterone and estrogen and repeated these experiments after an acute dose of ibuprofen (800 mg). In six women the hormones were exogenous (oral contraceptives); three women had regular menstrual cycles and were tested in the early follicular and midluteal phases. Resting oral temperature (Tor) was significantly elevated with high hormone status (P < 0.05); this was not affected by ibuprofen treatment (P > 0.2). The Tor threshold for cutaneous vasodilation was significantly increased by high hormone status (+0.27 +/- 0.07 degrees C, P < 0. 02); the shift was not affected by ibuprofen treatment (with ibuprofen: +0.29 +/- 0.08 degrees C, P > 0.2 vs. control experiments). The Tor threshold for sweating was similarly increased by high hormone status (+0.22 +/- 0.05 degrees C, P < 0.05); this shift was not influenced by ibuprofen (with ibuprofen: +0.35 +/- 0. 05, P > 0.1 vs. control experiments). Thus the shift in thermoregulatory control of skin blood flow and sweating mediated by female reproductive steroids is not sensitive to ibuprofen; it therefore appears that this shift is independent of prostaglandins. (+info)Venous thromboembolic disease and combined oral contraceptives: A re-analysis of the MediPlus database. (3/254)
In October 1995 the Committee on Safety of Medicines advised UK doctors and pharmacists that oral contraceptives containing desogestrel and gestodene were associated with double the risk of venous thromboembolic events (VTE) compared to pills containing other progestogens. In 1997 data was analysed from the MediPlus database of UK general practitioner records, which reported odds ratios for desogestrel and gestodene lower than that for levonorgestrel. Here the results of a more stringent nested case control analysis on the MediPlus database are reported. The study was larger and cases were verified. A crude incidence of idiopathic VTE was found amongst users of combined oral contraceptives of 4.6 per 10 000 exposed women years. Using levonorgestrel 150 microg + ethinyloestradiol 30 microg as reference, non-significant odds ratios of 1.1 (0.5-2.6) for desogestrel 150 microg + ethinyloestradiol 30 microg and 1.1 (0.5-2.4) for gestodene 75 microg + ethinyloestradiol 30 microg were found. The results of this study show no significant difference in risk between different formulations of combined oral contraceptive. (+info)Oral contraceptives and myocardial infarction: results of the MICA case-control study. (4/254)
OBJECTIVES: To determine the association between myocardial infarction and use of different types of oral contraception in young women. DESIGN: Community based case-control study. Data from interviews and general practice records. SETTING: England, Scotland, and Wales. PARTICIPANTS: Cases (n=448) were recruited from women aged between 16 and 44 who had suffered an incident myocardial infarction between 1 October 1993 and 16 October 1995. Controls (n=1728) were women without a diagnosis of myocardial infarction matched for age and general practice. MAIN OUTCOME MEASURES: Odds ratios for myocardial infarction in current users of all combined oral contraceptives stratified by their progestagen content compared with non-users; current users of third generation versus second generation oral contraceptives. RESULTS: The adjusted odds ratio for myocardial infarction was 1.40 (95% confidence interval 0.78 to 2. 52) for all combined oral contraceptive users, 1.10 (0.52 to 2.30) for second generation users, and 1.96 (0.87 to 4.39) for third generation users. Subgroup analysis by progestagen content did not show any significant difference from 1, and there was no effect of duration of use. The adjusted odds ratio for third generation users versus second generation users was 1.78 (0.66 to 4.83). 87% of cases were not exposed to an oral contraceptive, and 88% had clinical cardiovascular risk factors or were smokers, or both. Smoking was strongly associated with myocardial infarction: adjusted odds ratio 12.5 (7.29 to 21.5) for smoking 20 or more cigarettes a day. CONCLUSIONS: There was no significant association between the use of oral contraceptives and myocardial infarction. The modest and non-significant point estimates for this association have wide confidence intervals. There was no significant difference between second and third generation products. (+info)Combined oral contraceptives, smoking, and cardiovascular risk. (5/254)
STUDY OBJECTIVE: To assess age specific incidence and mortality of stroke, acute myocardial infarction (AMI), and idiopathic venous thromboembolism (VTE) associated with use of modern low dose combined oral contraceptives (OCs) and the interaction with smoking. DESIGN: Hospital-based case-control study. SETTING: Hospitals in Oxford region in the United Kingdom, which covered a defined population, during the period 1989-1993. METHODS: Relative risk estimates from the WHO Collaborative Study and observed incidence rates from the Oxford region were used to estimate age specific incidence of each disease among women without cardiovascular risk factors and model total cardiovascular incidence and mortality. RESULTS: Among women who did not use OCs, smoke nor had any other cardiovascular risk factors, total incidence of stroke and AMI were less than 2 events per 100,000 woman years in those aged 20-24 years and rose exponentially with age to 8 events per 100,000 among women aged 40-44 years. Incidence of idiopathic VTE among women who did not use OCs rose linearly with age (from 3.3 per 100,000 at ages 20-24 years to 5.8 per 100,000 at ages 40-44 years). The increased risk of idiopathic VTE associated with OC use among non-smokers constituted over 90% of all cardiovascular events for women aged 20-24 years and more than 60% in those aged 40-44 years. Fatal cardiovascular events were dominated by haemorrhagic stroke and AMI, and among OC users who smoked these two diseases accounted for 80% of cardiovascular deaths among women aged 20-24 years, rising to 97% among those aged 40-44 years. Cardiovascular mortality associated with smoking was greater than that associated with OC use at all ages. Attributable risk associated with OC use was 1 death per 370,000 users annually among women aged 20-24 years, 1 per 170,000 at ages 30-34 years, and 1 per 37,000 at ages 40-44 years. Among smokers, the cardiovascular mortality attributable to OC use was estimated to be about 1 per 100,000 users annually among women aged less than 35 years, and about 1 per 10,000 users annually among those above the age of 35 years. CONCLUSION: The incidence of fatal cardiovascular events among women aged less than 35 years is low. The VTE risk associated with OC use is the largest contributor to OC induced adverse effects. The potentially avoidable excess VTE risk associated with the newer progestogens desogestrel and gestodene would account for a substantial proportion of total cardiovascular morbidity in this age group. For women over age 35 years the absolute risks associated with OC use and smoking are greater because of the steeply rising incidence of arterial diseases. The combination of smoking and OC use among such women is associated with particularly increased risks. Any potential reduction in AMI or stroke risk with use of third generation OCs would be a more important consideration among older compared with younger women, particularly if they smoke. However, the mortality associated with smoking is far greater than that associated with OC use (of any type) at all ages. (+info)Oral contraceptives and oral antibiotics: interactions and advice in an accident and emergency setting. (6/254)
OBJECTIVE: (1) To determine what advice, if any, would be given by accident and emergency (A&E) doctors to women who were taking the combined oral contraceptive pill (OCP) if they had been issued with broad spectrum antibiotics and (2) after an audit programme had been instigated, whether appropriate advice was given to such women. METHODS: A questionnaire was circulated to 12 doctors working in the Exeter A&E department to assess their level of knowledge in prescribing antibiotics to women taking the OCP. Notes of women aged 15-50 who had been prescribed broad spectrum antibiotics were examined to see if a contraceptive history had been taken. If the patient was found to be taking the combined OCP it was noted whether documented advice had been given about using an additional form of contraception. Six months later after two education sessions had been held, prescriptions and notes were examined. A patient education leaflet was produced to be given to these women, indicating what additional precautions should be taken after having been prescribed antibiotics. SETTING: The A&E department of a busy district general hospital. SUBJECTS: Women aged 15-50 who had been issued with broad spectrum antibiotics. RESULTS: The level of knowledge in regard to contraceptive advice given to women taking the OCP among doctors working in an A&E department was poor. However, after educational sessions and the production of a patient information leaflet, there was an improvement in women receiving correct advice. CONCLUSIONS: The clinical significance of drug interactions between oral contraceptives and antibiotics indicates the importance of asking a full contraceptive drug history of any woman of childbearing age and documenting this in the notes. Regular audit of this topic is needed to keep it at the front of doctors' minds. (+info)Antibiotics, the pill, and pregnancy. (7/254)
OBJECTIVES: To establish if advice concerning risks of pregnancy when taking oral contraceptive pill and antibiotics is being offered. METHOD: A retrospective audit of notes of 100 female patients aged 15-39 who were prescribed antibiotics. RESULTS: Documentation of use of contraception was noted in 3% of patients. Advice concerning risks and further precautions was noted in this 3% but not in any other records. CONCLUSION: The audit identified a gap in documentation and/or clinical practice in advising women of childbearing age of the risk of conceiving when using oral contraceptive pill and antibiotics. Recommendations are given as to how this may be addressed. (+info)Effects of progestins on cardiovascular diseases: the haemostatic system. (8/254)
The effect of progestin-only therapy on the haemostatic system has mainly been studied in premenopausal women. Although these studies are difficult to compare, most authors agree that there is no consistent pattern of effects on haemostasis. Oestrogen-progestin combinations have been extensively studied in pre- (combined oral contraceptives) and postmenopausal women (sequential and continuous combined hormone replacement therapy), but mostly with emphasis on the effects of oestrogens. Comparative studies into the differential effects of progestins in combined preparations are scarce. Based on these studies, there is evidence for modifying effects of progestins on oestrogen-induced changes, particularly on fibrinogen, factor VII and the fibrinolytic system. The modifying effects appear to vary among certain progestins, the variation being most likely due to differential effects on lipid metabolism. The clinical interpretation of steroid-induced effects on the haemostatic system is difficult. Retrospective analyses linking certain patterns of haemostatic regulation to the risk of venous or arterial vascular diseases are subject to bias, and no interventional studies are yet available. In the absence of such prospective studies and well-designed comparative studies, the available data do not support the notion of a superiority of certain progestins with regard to cardiovascular risks of combined preparations. (+info)Also known as: Menstrual Disorders, Menstrual Abnormalities, Dysmenorrhea, Amenorrhea, Oligomenorrhea, Polymenorrhea.
Symptoms of a uterine hemorrhage may include:
* Vaginal bleeding that may be heavy or light in flow
* Pain in the lower abdomen
* Pain during sexual activity
* Spotting or bleeding between menstrual periods
* Unusual discharge from the vagina
If you experience any of these symptoms, it is important to seek medical attention as soon as possible. Uterine hemorrhages can be diagnosed through a physical examination and imaging tests such as ultrasound or MRI. Treatment depends on the underlying cause of the bleeding, but may include medications to control bleeding, surgery to remove fibroids or polyps, or hysterectomy in severe cases.
It is important to note that while uterine hemorrhages can be managed with appropriate medical care, they can also be life-threatening if left untreated. Seeking prompt medical attention and following the advice of your healthcare provider are crucial to preventing complications and ensuring a successful outcome.
Metrorrhagia can be diagnosed through a pelvic exam, ultrasound or hysteroscopy. Treatment options depend on the underlying cause of the condition, and may include medications to regulate hormones or shrink fibroids, or surgery to remove polyps or fibroids. It is important for women who experience metrorrhagia to consult a healthcare provider for proper diagnosis and treatment to rule out any serious underlying conditions such as endometrial cancer.
Word origin: Greek "metro" meaning month + "rhagia" meaning flow.
STDs can cause a range of symptoms, including genital itching, burning during urination, unusual discharge, and painful sex. Some STDs can also lead to long-term health problems, such as infertility, chronic pain, and an increased risk of certain types of cancer.
STDs are usually diagnosed through a physical exam, blood tests, or other diagnostic tests. Treatment for STDs varies depending on the specific infection and can include antibiotics, antiviral medication, or other therapies. It's important to practice safe sex, such as using condoms, to reduce the risk of getting an STD.
Some of the most common STDs include:
* Chlamydia: A bacterial infection that can cause genital itching, burning during urination, and unusual discharge.
* Gonorrhea: A bacterial infection that can cause similar symptoms to chlamydia.
* Syphilis: A bacterial infection that can cause a painless sore on the genitals, followed by a rash and other symptoms.
* Herpes: A viral infection that can cause genital itching, burning during urination, and painful sex.
* HPV: A viral infection that can cause genital warts and increase the risk of cervical cancer.
* HIV/AIDS: A viral infection that can cause a range of symptoms, including fever, fatigue, and weight loss, and can lead to AIDS if left untreated.
It's important to note that some STDs can be spread through non-sexual contact, such as sharing needles or mother-to-child transmission during childbirth. It's also important to know that many STDs can be asymptomatic, meaning you may not have any symptoms even if you are infected.
If you think you may have been exposed to an STD, it's important to get tested as soon as possible. Many STDs can be easily treated with antibiotics or other medications, but if left untreated, they can lead to serious complications and long-term health problems.
It's also important to practice safe sex to reduce the risk of getting an STD. This includes using condoms, as well as getting vaccinated against HPV and Hepatitis B, which are both common causes of STDs.
In addition to getting tested and practicing safe sex, it's important to be aware of your sexual health and the risks associated with sex. This includes being aware of any symptoms you may experience, as well as being aware of your partner's sexual history and any STDs they may have. By being informed and proactive about your sexual health, you can help reduce the risk of getting an STD and maintain good sexual health.
Causes:
There are several possible causes of amenorrhea, including:
1. Hormonal Imbalance: Imbalance of hormones can prevent the uterus from preparing for menstruation.
2. Pregnancy: Pregnancy is one of the most common causes of amenorrhea.
3. Menopause: Women going through menopause may experience amenorrhea due to the decreased levels of estrogen and progesterone.
4. Polycystic Ovary Syndrome (PCOS): PCOS is a hormonal disorder that can cause irregular periods or amenorrhea.
5. Thyroid Disorders: Both hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) can cause amenorrhea.
6. Obesity: Women who are significantly overweight may experience amenorrhea due to the hormonal imbalance caused by excess body fat.
7. Stress: Chronic stress can disrupt hormone levels and cause amenorrhea.
8. Surgery or Trauma: Certain surgeries, such as hysterectomy or removal of the ovaries, can cause amenorrhea. Trauma, such as a severe injury or infection, can also cause amenorrhea.
9. Medications: Certain medications, such as steroids and chemotherapy drugs, can cause amenorrhea as a side effect.
10. Endocrine Disorders: Disorders such as hypogonadotropic hypogonadism, hyperprolactinemia, and hypothyroidism can cause amenorrhea.
Symptoms:
Amenorrhea can cause a range of symptoms, including:
1. No menstrual period
2. Difficulty getting pregnant (infertility)
3. Abnormal vaginal bleeding or spotting
4. Painful intercourse
5. Weight gain or loss
6. Mood changes, such as anxiety or depression
7. Fatigue
8. Headaches
9. Insomnia
10. Hot flashes
Diagnosis:
Amenorrhea is typically diagnosed based on a patient's medical history and physical examination. Additional tests may be ordered to determine the underlying cause of amenorrhea, such as:
1. Blood tests to measure hormone levels, including estrogen, progesterone, and thyroid-stimulating hormone (TSH)
2. Imaging tests, such as ultrasound or MRI, to evaluate the ovaries and uterus
3. Laparoscopy, a minimally invasive procedure that allows the doctor to visually examine the ovaries and fallopian tubes
4. Hysteroscopy, a procedure that allows the doctor to examine the inside of the uterus
Treatment:
The treatment of amenorrhea depends on the underlying cause. Some common treatments include:
1. Hormone replacement therapy (HRT) to restore hormone balance and promote menstruation
2. Medications to stimulate ovulation, such as clomiphene citrate or letrozole
3. Surgery to remove fibroids, cysts, or other structural abnormalities that may be contributing to amenorrhea
4. Infertility treatments, such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI), if the patient is experiencing difficulty getting pregnant
5. Lifestyle changes, such as weight loss or exercise, to improve overall health and promote menstruation
Prevention:
There is no specific way to prevent amenorrhea, but maintaining a healthy lifestyle and managing any underlying medical conditions can help reduce the risk of developing the condition. Some tips for prevention include:
1. Eating a balanced diet that includes plenty of fruits, vegetables, whole grains, and lean protein sources
2. Exercising regularly to maintain a healthy weight and improve overall health
3. Managing stress through relaxation techniques, such as yoga or meditation
4. Getting enough sleep each night
5. Avoiding excessive alcohol consumption and smoking
6. Maintaining a healthy body mass index (BMI) to reduce the risk of developing hormonal imbalances
7. Managing any underlying medical conditions, such as polycystic ovary syndrome (PCOS), thyroid disorders, or adrenal gland disorders
8. Avoiding exposure to harmful chemicals and toxins that can disrupt hormone balance.
Thromboembolism can be caused by a variety of factors, such as injury, surgery, cancer, and certain medical conditions like atrial fibrillation. It can also be inherited or acquired through genetic mutations.
The symptoms of thromboembolism depend on the location of the clot and the severity of the blockage. They may include:
* Swelling or redness in the affected limb
* Pain or tenderness in the affected area
* Weakness or numbness in the affected limb
* Shortness of breath or chest pain if the clot has traveled to the lungs (pulmonary embolism)
* Dizziness, lightheadedness, or fainting
Thromboembolism can be diagnosed through a variety of tests, such as ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and blood tests. Treatment typically involves anticoagulant medications to prevent the clot from growing and to prevent new clots from forming. In some cases, thrombolysis or clot-busting drugs may be used to dissolve the clot. Filters can also be placed in the vena cava to prevent clots from traveling to the lungs.
Prevention of thromboembolism includes:
* Moving around regularly to improve blood flow
* Avoiding long periods of immobility, such as during long-distance travel
* Elevating the affected limb to reduce swelling
* Compression stockings to improve blood flow
* Avoiding smoking and managing weight
* Taking anticoagulant medications if recommended by a healthcare provider.
There are two main types of dysmenorrhea: primary and secondary. Primary dysmenorrhea is caused by uterine muscle contractions that occur during menstruation, while secondary dysmenorrhea is caused by an underlying medical condition such as endometriosis, fibroids, or pelvic inflammatory disease.
Symptoms of dysmenorrhea may include:
* Cramping pain in the lower abdomen, usually beginning before or at the onset of menstruation and lasting for 1-3 days
* Pain that can be sharp, dull, or throbbing
* Pelvic discomfort or heaviness
* Nausea and vomiting
* Diarrhea or constipation
* Headache
* Fatigue
* Mild fever
While dysmenorrhea is not a life-threatening condition, it can significantly impact a woman's quality of life, particularly during her reproductive years. The exact cause of primary dysmenorrhea is not fully understood, but it is believed to be related to the production of prostaglandins, hormone-like substances that cause uterine muscle contractions and increased blood flow to the pelvis.
Treatment for dysmenorrhea may include over-the-counter pain relievers such as ibuprofen or naproxen, as well as home remedies such as heat application, exercise, and relaxation techniques. In some cases, prescription medications or surgery may be necessary to address underlying conditions that are contributing to the dysmenorrhea.
It's important for women who experience severe or persistent dysmenorrhea to seek medical attention to rule out any underlying conditions that may need treatment. With proper diagnosis and management, most women with dysmenorrhea can find relief from their symptoms and lead normal, active lives.
Symptoms of venous thrombosis may include pain, swelling, warmth, and redness in the affected limb. In some cases, the clot can break loose and travel to the lungs, causing a potentially life-threatening condition called Pulmonary Embolism (PE).
Treatment for venous thrombosis typically involves anticoagulant medications to prevent the clot from growing and to prevent new clots from forming. In some cases, a filter may be placed in the vena cava, the large vein that carries blood from the lower body to the heart, to prevent clots from traveling to the lungs.
Prevention of venous thrombosis includes encouraging movement and exercise, avoiding long periods of immobility, and wearing compression stockings or sleeves to compress the veins and improve blood flow.
There are several types of acne, including:
1. Comedonal acne: characterized by blackheads and whiteheads.
2. Inflammatory acne: characterized by papules, pustules, and nodules.
3. Cystic acne: characterized by large, painful cysts that can cause scarring.
4. Acne rosacea: a type of acne that occurs in adults, characterized by redness, flushing, and telangiectasias (small blood vessels).
There are several treatment options for acne vulgaris, including:
1. Topical treatments: such as benzoyl peroxide, salicylic acid, and sulfur.
2. Oral antibiotics: such as doxycycline and minocycline.
3. Retinoids: derived from vitamin A, used to unclog pores and reduce inflammation.
4. Hormonal therapies: such as birth control pills, used to regulate hormones that can contribute to acne.
5. Isotretinoin: a powerful oral medication used for severe cases of cystic acne that have not responded to other treatments.
6. Laser and light therapy: such as blue light therapy and photodynamic therapy, used to reduce inflammation and kill bacteria.
7. Lifestyle modifications: such as using non-comedogenic products, wearing sunscreen, and avoiding picking or popping pimples.
It is important to note that acne can be a persistent condition, and it may take time and experimentation to find the right treatment approach. It's best to consult with a dermatologist for personalized advice on treating acne vulgaris.
Causes of Menorrhagia
-------------------
There are several potential causes of menorrhagia, including:
1. Hormonal imbalance: Hormonal changes can lead to an imbalance in the uterus, causing excessive bleeding.
2. Uterine fibroids: These noncancerous growths in the uterus can cause heavy bleeding during menstruation.
3. Adenomyosis: This condition occurs when tissue similar to the lining of the uterus grows into the muscle of the uterus, leading to heavy bleeding.
4. Endometrial polyps: These are growths that can develop on the lining of the uterus and cause heavy bleeding.
5. Thyroid disorders: Both hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) can cause menorrhagia.
6. Pelvic inflammatory disease (PID): This is an infection of the reproductive organs that can cause scarring and lead to heavy bleeding.
7. IUDs: Intrauterine devices (IUDs) can cause heavy bleeding, especially during the first few months after insertion.
8. Medications: Certain medications such as anticoagulants and anti-inflammatory drugs can increase the risk of menorrhagia.
9. Bleeding disorders: Women with bleeding disorders, such as von Willebrand disease or platelet dysfunction, may experience heavy menstrual bleeding.
10. Cancer: In rare cases, menorrhagia can be a symptom of uterine cancer.
Symptoms of Menorrhagia
-------------------------
The primary symptom of menorrhagia is heavy menstrual bleeding that lasts for more than 7 days or bleeds that are heavier than usual. Other symptoms may include:
1. Soaking through sanitary products every hour or two
2. Using double sanitary products (e.g., a pad and a tampon) to control bleeding
3. Bleeding that lasts for more than 7 days
4. Menstrual blood clots larger than a quarter
5. Painful menstruation (dysmenorrhea)
6. Passing large blood clots during bowel movements or urination
7. Fatigue, dizziness, or fainting due to anemia
8. Weakness or shortness of breath
Diagnosis and Treatment of Menorrhagia
-------------------------------------
If you experience any of the symptoms of menorrhagia, it is important to see a healthcare provider for proper diagnosis and treatment. The healthcare provider will perform a physical examination and may order one or more of the following tests to determine the cause of heavy menstrual bleeding:
1. Complete Blood Count (CBC) to check for anemia and other blood abnormalities
2. Blood smear examination to look for abnormal cells or blood clotting disorders
3. Ultrasound to evaluate the uterus and ovaries
4. Endometrial biopsy to examine the lining of the uterus
5. Hysteroscopy to visualize the inside of the uterus
6. Laparoscopy to evaluate the pelvic organs
Treatment for menorrhagia depends on the underlying cause and may include:
1. Medications such as hormonal contraceptives, nonsteroidal anti-inflammatory drugs (NSAIDs), or iron supplements to control bleeding and anemia
2. Surgical procedures such as endometrial ablation or hysterectomy in severe cases that do not respond to other treatments
3. Lifestyle changes such as avoiding caffeine, alcohol, and spicy foods, as well as taking regular exercise and maintaining a healthy diet
4. Hormone replacement therapy (HRT) to regulate hormonal imbalances
5. Platelet transfusions or blood transfusions in cases of severe bleeding
It's important to note that menorrhagia can be a symptom of a more serious underlying condition, so it's essential to seek medical attention if you experience any of the following:
1. Prolonged or heavy menstrual bleeding (more than 7 days)
2. Bleeding between periods or after sex
3. Painful periods or difficulty using tampons
4. Fever, chills, or vomiting during menstruation
5. Unusual vaginal discharge or odor
6. Abdominal pain or bloating
Early diagnosis and treatment can help manage symptoms and prevent complications of menorrhagia, such as anemia, fatigue, and infertility.
There are two main types of thrombophlebitis:
1. Superficial thrombophlebitis: This type of thrombophlebitis affects the superficial veins, which are located just under the skin. It is often caused by injury or trauma to the vein, and it can cause redness, swelling, and pain in the affected area.
2. Deep vein thrombophlebitis: This type of thrombophlebitis affects the deep veins, which are located deeper in the body. It is often caused by blood clots that form in the legs or arms, and it can cause symptoms such as pain, swelling, and warmth in the affected limb.
Thrombophlebitis can be caused by a variety of factors, including:
1. Injury or trauma to the vein
2. Blood clotting disorders
3. Prolonged bed rest or immobility
4. Surgery or medical procedures
5. Certain medications, such as hormone replacement therapy or chemotherapy
6. Age, as the risk of developing thrombophlebitis increases with age
7. Family history of blood clotting disorders
8. Increased pressure on the veins, such as during pregnancy or obesity
Thrombophlebitis can be diagnosed through a variety of tests, including:
1. Ultrasound: This test uses sound waves to create images of the veins and can help identify blood clots or inflammation.
2. Venography: This test involves injecting a dye into the vein to make it visible under X-ray imaging.
3. Blood tests: These can be used to check for signs of blood clotting disorders or other underlying conditions that may be contributing to the development of thrombophlebitis.
Treatment for thrombophlebitis typically involves anticoagulation therapy, which is designed to prevent the blood clot from growing larger and to prevent new clots from forming. This can involve medications such as heparin or warfarin, or other drugs that work by blocking the production of clots. In some cases, a filter may be placed in the vena cava, the large vein that carries blood from the lower body to the heart, to prevent clots from traveling to the lungs.
In addition to anticoagulation therapy, treatment for thrombophlebitis may also include:
1. Elevation of the affected limb to reduce swelling
2. Compression stockings to help reduce swelling and improve blood flow
3. Pain management with medication or heat or cold applications
4. Antibiotics if there is an infection
5. Rest and avoiding strenuous activities until the symptoms resolve.
In some cases, surgery may be necessary to remove the clot or repair the affected vein.
It's important to note that early diagnosis and treatment of thrombophlebitis can help prevent complications such as infection, inflammation, or damage to the valves in the affected vein. If you suspect you or someone else may have thrombophlebitis, it is important to seek medical attention promptly.
Precancerous changes in the uterine cervix are called dysplasias, and they can be detected by a Pap smear, which is a routine screening test for women. If dysplasia is found, it can be treated with cryotherapy (freezing), laser therapy, or cone biopsy, which removes the affected cells.
Cervical cancer is rare in developed countries where Pap screening is widely available, but it remains a common cancer in developing countries where access to healthcare and screening is limited. The human papillomavirus (HPV) vaccine has been shown to be effective in preventing cervical precancerous changes and cancer.
Cervical cancer can be treated with surgery, radiation therapy, or chemotherapy, depending on the stage and location of the cancer. The prognosis for early-stage cervical cancer is good, but advanced-stage cancer can be difficult to treat and may have a poor prognosis.
The following are some types of uterine cervical neoplasms:
1. Adenocarcinoma in situ (AIS): This is a precancerous condition that occurs when glandular cells on the surface of the cervix become abnormal and grow out of control.
2. Cervical intraepithelial neoplasia (CIN): This is a precancerous condition that occurs when abnormal cells are found on the surface of the cervix. There are several types of CIN, ranging from mild to severe.
3. Squamous cell carcinoma: This is the most common type of cervical cancer and arises from the squamous cells that line the cervix.
4. Adnexal carcinoma: This is a rare type of cervical cancer that arises from the glands or ducts near the cervix.
5. Small cell carcinoma: This is a rare and aggressive type of cervical cancer that grows rapidly and can spread quickly to other parts of the body.
6. Micropapillary uterine carcinoma: This is a rare type of cervical cancer that grows in a finger-like shape and can be difficult to diagnose.
7. Clear cell carcinoma: This is a rare type of cervical cancer that arises from clear cells and can be more aggressive than other types of cervical cancer.
8. Adenocarcinoma: This is a type of cervical cancer that arises from glandular cells and can be less aggressive than squamous cell carcinoma.
9. Sarcoma: This is a rare type of cervical cancer that arises from the connective tissue of the cervix.
The treatment options for uterine cervical neoplasms depend on the stage and location of the cancer, as well as the patient's overall health and preferences. The following are some common treatments for uterine cervical neoplasms:
1. Hysterectomy: This is a surgical procedure to remove the uterus and may be recommended for early-stage cancers or precancerous changes.
2. Cryotherapy: This is a minimally invasive procedure that uses liquid nitrogen to freeze and destroy abnormal cells in the cervix.
3. Laser therapy: This is a minimally invasive procedure that uses a laser to remove or destroy abnormal cells in the cervix.
4. Cone biopsy: This is a surgical procedure to remove a small cone-shaped sample of tissue from the cervix to diagnose and treat early-stage cancers or precancerous changes.
5. Radiation therapy: This is a non-surgical treatment that uses high-energy rays to kill cancer cells and may be recommended for more advanced cancers or when the cancer has spread to other parts of the body.
6. Chemotherapy: This is a non-surgical treatment that uses drugs to kill cancer cells and may be recommended for more advanced cancers or when the cancer has spread to other parts of the body.
7. Immunotherapy: This is a non-surgical treatment that uses drugs to stimulate the immune system to fight cancer cells and may be recommended for more advanced cancers or when other treatments have failed.
8. Targeted therapy: This is a non-surgical treatment that uses drugs to target specific genes or proteins that contribute to cancer growth and development and may be recommended for more advanced cancers or when other treatments have failed.
It is important to note that the choice of treatment will depend on the stage and location of the cancer, as well as the patient's overall health and preferences. Patients should discuss their treatment options with their doctor and develop a personalized plan that is right for them.
There are different types of Breast Neoplasms such as:
1. Fibroadenomas: These are benign tumors that are made up of glandular and fibrous tissues. They are usually small and round, with a smooth surface, and can be moved easily under the skin.
2. Cysts: These are fluid-filled sacs that can develop in both breast tissue and milk ducts. They are usually benign and can disappear on their own or be drained surgically.
3. Ductal Carcinoma In Situ (DCIS): This is a precancerous condition where abnormal cells grow inside the milk ducts. If left untreated, it can progress to invasive breast cancer.
4. Invasive Ductal Carcinoma (IDC): This is the most common type of breast cancer and starts in the milk ducts but grows out of them and invades surrounding tissue.
5. Invasive Lobular Carcinoma (ILC): It originates in the milk-producing glands (lobules) and grows out of them, invading nearby tissue.
Breast Neoplasms can cause various symptoms such as a lump or thickening in the breast or underarm area, skin changes like redness or dimpling, change in size or shape of one or both breasts, discharge from the nipple, and changes in the texture or color of the skin.
Treatment options for Breast Neoplasms may include surgery such as lumpectomy, mastectomy, or breast-conserving surgery, radiation therapy which uses high-energy beams to kill cancer cells, chemotherapy using drugs to kill cancer cells, targeted therapy which uses drugs or other substances to identify and attack cancer cells while minimizing harm to normal cells, hormone therapy, immunotherapy, and clinical trials.
It is important to note that not all Breast Neoplasms are cancerous; some are benign (non-cancerous) tumors that do not spread or grow.
Some common examples of drug-induced abnormalities include:
1. Allergic reactions: Some drugs can cause an allergic reaction, which can lead to symptoms such as hives, itching, swelling, and difficulty breathing.
2. Side effects: Many drugs can cause side effects, such as nausea, dizziness, and fatigue, which can be mild or severe.
3. Toxic reactions: Some drugs can cause toxic reactions, which can damage the body's organs and tissues.
4. Autoimmune disorders: Certain drugs can trigger autoimmune disorders, such as lupus or rheumatoid arthritis, which can cause a range of symptoms including joint pain, fatigue, and skin rashes.
5. Gastrointestinal problems: Some drugs can cause gastrointestinal problems, such as stomach ulcers, diarrhea, or constipation.
6. Neurological disorders: Certain drugs can cause neurological disorders, such as seizures, tremors, and changes in mood or behavior.
7. Cardiovascular problems: Some drugs can increase the risk of cardiovascular problems, such as heart attack or stroke.
8. Metabolic changes: Certain drugs can cause metabolic changes, such as weight gain or loss, and changes in blood sugar levels.
9. Endocrine disorders: Some drugs can affect the body's endocrine system, leading to hormonal imbalances and a range of symptoms including changes in mood, energy levels, and sexual function.
10. Kidney damage: Certain drugs can cause kidney damage or failure, especially in people with pre-existing kidney problems.
It's important to note that not all drugs will cause side effects, and the severity of side effects can vary depending on the individual and the specific drug being taken. However, it's important to be aware of the potential risks associated with any medication you are taking, and to discuss any concerns or questions you have with your healthcare provider.
There are different types of uterine perforation, including:
1. Cervical perforation: A tear in the cervix, which is the lower part of the uterus that opens into the vagina.
2. Uterine wall perforation: A tear or hole in the muscular wall of the uterus, which can be caused by instruments used during surgery or delivery.
3. Endometrial perforation: A tear in the lining of the uterus (endometrium), which is more common during invasive procedures such as hysteroscopy or endometrial ablation.
Symptoms of uterine perforation may include:
* Severe abdominal pain
* Heavy vaginal bleeding
* Fever
* Nausea and vomiting
If you suspect that you have a uterine perforation, it is essential to seek medical attention immediately. Your healthcare provider will perform a physical examination and order imaging tests such as ultrasound or CT scan to confirm the diagnosis and determine the extent of the damage. Treatment options may include:
1. Observation: In mild cases, the body may be able to heal on its own without any intervention.
2. Surgery: Depending on the severity of the perforation, surgical repair or removal of the damaged tissue may be necessary.
3. Antibiotics: If there is an infection, antibiotics will be prescribed to treat it.
4. Blood transfusions: In cases where there is significant bleeding, blood transfusions may be required.
Prevention of uterine perforation is crucial, and it involves proper training and use of instruments during surgery or delivery, as well as careful monitoring of the patient's condition during these procedures.
Benign ovarian neoplasms include:
1. Serous cystadenoma: A fluid-filled sac that develops on the surface of the ovary.
2. Mucinous cystadenoma: A tumor that is filled with mucin, a type of protein.
3. Endometrioid tumors: Tumors that are similar to endometrial tissue (the lining of the uterus).
4. Theca cell tumors: Tumors that develop in the supportive tissue of the ovary called theca cells.
Malignant ovarian neoplasms include:
1. Epithelial ovarian cancer (EOC): The most common type of ovarian cancer, which arises from the surface epithelium of the ovary.
2. Germ cell tumors: Tumors that develop from germ cells, which are the cells that give rise to eggs.
3. Stromal sarcomas: Tumors that develop in the supportive tissue of the ovary.
Ovarian neoplasms can cause symptoms such as pelvic pain, abnormal bleeding, and abdominal swelling. They can also be detected through pelvic examination, imaging tests such as ultrasound and CT scan, and biopsy. Treatment options for ovarian neoplasms depend on the type, stage, and location of the tumor, and may include surgery, chemotherapy, and radiation therapy.
The symptoms of intrauterine device migration can vary depending on the location and size of the migrated IUD. Some common symptoms include:
* Abnormal bleeding or spotting
* Painful menstrual cramps
* Difficulty inserting or removing the IUD during routine check-ups
* Fever, chills, or other signs of infection
If intrauterine device migration is suspected, a healthcare provider will typically perform a physical examination and order imaging tests, such as an ultrasound or X-ray, to confirm the location and size of the migrated IUD. Treatment options for intrauterine device migration depend on the severity of the complication and can include:
* Removal of the migrated IUD
* Insertion of a new IUD in a different location
* Antibiotics to treat any underlying infections
* Surgical intervention to repair any damage caused by the migrated IUD.
It is important for women who use intrauterine devices (IUDs) as a form of birth control to be aware of the risk of migration and seek medical attention if they experience any symptoms that may indicate a problem with their IUD. Regular check-ups with a healthcare provider can help detect any issues early on and prevent complications associated with intrauterine device migration.
The exact cause of PMS is not known, but it is thought to be related to changes in hormone levels, particularly estrogen and progesterone, which can affect the brain and body. Some women may be more susceptible to PMS due to factors such as stress, genetics, or other medical conditions.
Common symptoms of PMS include:
1. Mood changes: anxiety, irritability, sadness, and mood swings
2. Physical symptoms: breast tenderness, bloating, cramps, headaches, and fatigue
3. Behavioral changes: changes in appetite, sleep patterns, and social withdrawal
4. Cognitive changes: difficulty concentrating, memory problems, and confusion
There is no single test for PMS, and diagnosis is based on a combination of symptoms, medical history, and ruling out other conditions that may cause similar symptoms. Treatment for PMS usually involves a combination of lifestyle changes, over-the-counter medications, and prescription medications, depending on the severity of symptoms.
Some common lifestyle changes that can help manage PMS include:
1. Exercise regularly: regular physical activity can help reduce symptoms of PMS
2. Eat a balanced diet: a healthy, nutrient-rich diet can help alleviate symptoms
3. Get enough sleep: adequate rest and relaxation can help improve mood and reduce fatigue
4. Reduce stress: stress management techniques such as meditation, yoga, or deep breathing can help reduce the impact of PMS
Over-the-counter medications that may be used to treat PMS include:
1. Nonsteroidal anti-inflammatory drugs (NSAIDs): these medications can help reduce cramps, bloating, and breast tenderness
2. Antihistamines: these medications can help with sleep disturbances and mood changes
3. Acetaminophen: this medication can help with headaches and other painful symptoms
Prescription medications that may be used to treat PMS include:
1. Hormonal birth control: oral contraceptives can help regulate hormones and reduce symptoms of PMS
2. Selective serotonin reuptake inhibitors (SSRIs): these medications can help with mood changes, anxiety, and depression associated with PMS
3. Gabapentin: this medication can help with painful symptoms such as cramps and breast tenderness
It's important to note that the specific treatment plan for PMS will depend on the severity of symptoms and individual factors such as medical history, age, and other health conditions. It's best to consult a healthcare provider to determine the most appropriate course of treatment.
Deep Vein Thrombosis (DVT): DVT occurs when a blood clot forms in the deep veins of the body, usually in the legs. This can cause swelling, pain, and warmth in the affected area.
Pulmonary Embolism (PE): PE occurs when a blood clot from the deep veins of the body travels to the lungs, causing shortness of breath, chest pain, and coughing up bloody mucus.
The risk factors for VTE include:
* Prolonged immobility (e.g., long-distance travel or bed rest)
* Injury or surgery
* Age > 60 years
* Family history of VTE
* Cancer and its treatment
* Hormone replacement therapy or birth control pills
* Inherited blood-clotting disorders
* Inflammatory bowel disease
Prevention methods include:
* Moving around regularly during long-distance travel or bed rest
* Avoiding crossing your legs or ankles, which can restrict blood flow
* Wearing compression stockings during travel or when advised by a healthcare professional
* Elevating the affected leg when sitting or lying down
* Taking blood-thinning medication as prescribed by a healthcare professional
Early diagnosis and treatment of VTE can help prevent serious complications such as PE. Treatment options include anticoagulant medications, thrombolysis (dissolving the clot), and filtration devices.
Symptoms of PID may include:
* Abdominal pain
* Fever
* Heavy vaginal discharge with a strong odor
* Pain during sex
* Painful urination
PID can be diagnosed through a combination of physical examination, medical history, and diagnostic tests such as pelvic exams, ultrasound, or blood tests. Treatment typically involves antibiotics to clear the infection, and may also involve hospitalization for severe cases. In some cases, surgery may be necessary to repair any damage caused by the infection.
Preventive measures for PID include:
* Safe sexual practices, such as using condoms and avoiding sexual intercourse during outbreaks of STIs
* Regular gynecological exams and screening for STIs
* Avoiding the use of douches or other products that can disrupt the natural balance of bacteria in the vagina.
* Rashes, lesions, or sores
* Redness, swelling, or inflammation
* Skin thickening or thinning
* Pigmentation changes
* Growths or tumors
* Ulcers or wounds that do not heal properly
Skin manifestations can be a symptom of a wide range of medical conditions, including:
* Infections such as bacterial, fungal, or viral infections
* Autoimmune disorders such as psoriasis, eczema, or lupus
* Cancer such as melanoma, squamous cell carcinoma, or basal cell carcinoma
* Genetic conditions such as ichthyosis or epidermolysis bullosa
* Metabolic disorders such as diabetes or kidney disease
* Nutritional deficiencies such as vitamin deficiency or malnutrition
Skin manifestations can be diagnosed through a combination of physical examination, medical history, and diagnostic tests such as biopsy, blood tests, or imaging studies. Treatment options vary depending on the underlying condition and may include topical medications, systemic medications, surgery, or lifestyle changes.
In some cases, skin manifestations can be a sign of a more serious underlying condition that requires prompt medical attention. It is important to seek medical advice if you notice any unusual changes in your skin or if you experience any symptoms such as pain, itching, or bleeding.
Some of the symptoms of hirsutism include:
* Thick, dark hair on the face, chest, back, and buttocks
* Hair growth on the arms, legs, and other areas of the body
* Thinning or loss of hair on the head
* Acne and oily skin
Hirsutism can be caused by a variety of factors, including:
* Hormonal imbalances: Excessive levels of androgens, such as testosterone, can cause hirsutism.
* Genetics: Inheritance plays a role in the development of hirsutism.
* Medications: Certain medications, such as anabolic steroids and certain antidepressants, can cause hirsutism as a side effect.
* Other medical conditions: Polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia (CAH), and other endocrine disorders can also cause hirsutism.
There are several treatment options for hirsutism, including:
* Medications such as anti-androgens and retinoids to reduce hair growth and improve skin texture
* Electrolysis and laser therapy to remove unwanted hair
* Hormonal therapies such as birth control pills and spironolactone to regulate hormone levels and reduce hair growth
* Plastic surgery to remove excess hair-bearing skin.
It is important for individuals with hirsutism to seek medical attention if they experience any of the following symptoms:
* Sudden or excessive hair growth
* Hair growth on the face, chest, back, or buttocks
* Thinning or loss of hair on the head
* Acne and oily skin.
Early diagnosis and treatment can help manage the symptoms of hirsutism and improve quality of life for individuals affected by this condition.
1. Atrial fibrillation (a type of irregular heartbeat)
2. Heart disease or valve problems
3. Blood clots in the legs or lungs
4. Infective endocarditis (an infection of the heart valves)
5. Cancer and its treatment
6. Trauma to the head or neck
7. High blood pressure
8. Atherosclerosis (the buildup of plaque in the arteries)
When a blockage occurs in one of the blood vessels of the brain, it can deprive the brain of oxygen and nutrients, leading to cell death and potentially causing a range of symptoms including:
1. Sudden weakness or numbness in the face, arm, or leg
2. Sudden confusion or trouble speaking or understanding speech
3. Sudden trouble seeing in one or both eyes
4. Sudden severe headache
5. Dizziness or loss of balance
6. Fainting or falling
Intracranial embolism and thrombosis can be diagnosed through a variety of imaging tests, including:
1. Computed tomography (CT) scan
2. Magnetic resonance imaging (MRI)
3. Magnetic resonance angiography (MRA)
4. Cerebral angiography
5. Doppler ultrasound
Treatment options for intracranial embolism and thrombosis depend on the underlying cause of the blockage, but may include:
1. Medications to dissolve blood clots or prevent further clotting
2. Surgery to remove the blockage or repair the affected blood vessel
3. Endovascular procedures, such as angioplasty and stenting, to open up narrowed or blocked blood vessels
4. Supportive care, such as oxygen therapy and pain management, to help manage symptoms and prevent complications.
There are several types of thrombophilia, including:
1. Factor V Leiden: This is the most common inherited thrombophilia and is caused by a mutation in the Factor V gene.
2. Prothrombin G20210A: This is another inherited thrombophilia that is caused by a mutation in the Prothrombin gene.
3. Protein C and S deficiency: These are acquired deficiencies of protein C and S, which are important proteins that help to prevent blood clots.
4. Antiphospholipid syndrome: This is an autoimmune disorder that causes the body to produce antibodies against phospholipids, which can lead to blood clots.
5. Cancer-associated thrombophilia: This is a condition where cancer patients are at a higher risk of developing blood clots due to their cancer and its treatment.
6. Hormone-related thrombophilia: This is a condition where hormonal changes, such as those that occur during pregnancy or with the use of hormone replacement therapy, increase the risk of blood clots.
7. Inherited platelet disorders: These are rare conditions that affect the way platelets function and can increase the risk of blood clots.
8. Anti-cardiolipin antibodies: These are autoantibodies that can cause blood clots.
9. Lupus anticoagulant: This is an autoantibody that can cause blood clots.
10. Combined genetic and acquired risk factors: Some people may have a combination of inherited and acquired risk factors for thrombophilia.
Thrombophilia can be diagnosed through various tests, including:
1. Blood tests: These tests measure the levels of certain proteins in the blood that are associated with an increased risk of blood clots.
2. Genetic testing: This can help identify inherited risk factors for thrombophilia.
3. Imaging tests: These tests, such as ultrasound and venography, can help doctors visualize the blood vessels and look for signs of blood clots.
4. Thrombin generation assay: This test measures the body's ability to produce thrombin, a protein that helps form blood clots.
5. Platelet function tests: These tests assess how well platelets work and whether they are contributing to the development of blood clots.
Treatment for thrombophilia usually involves medications to prevent or dissolve blood clots, as well as measures to reduce the risk of developing new clots. These may include:
1. Anticoagulant drugs: These medications, such as warfarin and heparin, are used to prevent blood clots from forming.
2. Thrombolytic drugs: These medications are used to dissolve blood clots that have already formed.
3. Compression stockings: These stockings can help reduce swelling and improve blood flow in the affected limb.
4. Elevating the affected limb: This can help reduce swelling and improve blood flow.
5. Avoiding long periods of immobility: This can help reduce the risk of developing blood clots.
In some cases, surgery may be necessary to remove a blood clot or repair a damaged blood vessel. In addition, people with thrombophilia may need to make lifestyle changes, such as avoiding long periods of immobility and taking regular breaks to move around, to reduce their risk of developing blood clots.
Overall, the prognosis for thrombophilia is generally good if the condition is properly diagnosed and treated. However, if left untreated, thrombophilia can lead to serious complications, such as pulmonary embolism or stroke, which can be life-threatening. It is important for people with thrombophilia to work closely with their healthcare provider to manage the condition and reduce the risk of complications.
Teratogens can include drugs, alcohol, certain chemicals, and even some viral infections. Exposure to these substances during pregnancy can interfere with normal fetal development, leading to a wide range of birth defects, including physical abnormalities such as heart defects or facial deformities, as well as cognitive and behavioral disorders such as autism or learning disabilities.
The study of teratogenesis is known as teratology, and it plays an important role in helping healthcare providers understand the causes of birth defects and develop strategies for preventing them. By identifying and avoiding teratogens during pregnancy, women can help ensure a healthy and normal fetal development.
HIV (human immunodeficiency virus) infection is a condition in which the body is infected with HIV, a type of retrovirus that attacks the body's immune system. HIV infection can lead to AIDS (acquired immunodeficiency syndrome), a condition in which the immune system is severely damaged and the body is unable to fight off infections and diseases.
There are several ways that HIV can be transmitted, including:
1. Sexual contact with an infected person
2. Sharing of needles or other drug paraphernalia with an infected person
3. Mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Blood transfusions ( although this is rare in developed countries due to screening processes)
5. Organ transplantation (again, rare)
The symptoms of HIV infection can be mild at first and may not appear until several years after infection. These symptoms can include:
1. Fever
2. Fatigue
3. Swollen glands in the neck, armpits, and groin
4. Rash
5. Muscle aches and joint pain
6. Night sweats
7. Diarrhea
8. Weight loss
If left untreated, HIV infection can progress to AIDS, which is a life-threatening condition that can cause a wide range of symptoms, including:
1. Opportunistic infections (such as pneumocystis pneumonia)
2. Cancer (such as Kaposi's sarcoma)
3. Wasting syndrome
4. Neurological problems (such as dementia and seizures)
HIV infection is diagnosed through a combination of blood tests and physical examination. Treatment typically involves antiretroviral therapy (ART), which is a combination of medications that work together to suppress the virus and slow the progression of the disease.
Prevention methods for HIV infection include:
1. Safe sex practices, such as using condoms and dental dams
2. Avoiding sharing needles or other drug-injecting equipment
3. Avoiding mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Post-exposure prophylaxis (PEP), which is a short-term treatment that can prevent infection after potential exposure to the virus
5. Pre-exposure prophylaxis (PrEP), which is a daily medication that can prevent infection in people who are at high risk of being exposed to the virus.
It's important to note that HIV infection is manageable with proper treatment and care, and that people living with HIV can lead long and healthy lives. However, it's important to be aware of the risks and take steps to prevent transmission.
A vitamin B6 deficiency happens when the body does not get enough of this essential nutrient. Vitamin B6 is needed for many bodily functions, such as making new blood cells, keeping the nervous system healthy, and helping to convert food into energy.
The symptoms of a vitamin B6 deficiency can range from mild to severe and may include:
1. Fatigue or weakness: A lack of vitamin B6 can cause tiredness, weakness, and a general feeling of being unwell.
2. Irritability or depression: Vitamin B6 plays a role in the production of neurotransmitters, such as serotonin and dopamine, which are important for mood regulation. A deficiency can lead to feelings of irritability, anxiety, and depression.
3. Nausea and vomiting: Vitamin B6 helps with the absorption of nutrients from food, so a deficiency can cause nausea and vomiting.
4. Skin problems: Vitamin B6 is important for the health of the skin, and a deficiency can lead to conditions such as acne, eczema, and dermatitis.
5. Weight loss: A vitamin B6 deficiency can make it harder to gain weight or maintain weight loss.
Causes of Vitamin B6 Deficiency:
1. Poor diet: A diet that is low in vitamin B6 can lead to a deficiency. Foods rich in vitamin B6 include meat, fish, poultry, whole grains, and leafy green vegetables.
2. Malabsorption: Certain medical conditions, such as celiac disease or inflammatory bowel disease, can make it harder for the body to absorb vitamin B6 from food.
3. Pregnancy and breastfeeding: Women who are pregnant or breastfeeding have a higher need for vitamin B6 and may be more likely to develop a deficiency if they do not consume enough of this nutrient.
4. Alcoholism: Heavy alcohol consumption can interfere with the absorption of vitamin B6, leading to a deficiency.
5. Certain medications: Some medications, such as antidepressants and anti-inflammatory drugs, can interfere with the absorption of vitamin B6.
Signs and Symptoms of Vitamin B6 Deficiency:
1. Depression or anxiety
2. Fatigue or weakness
3. Irritability or mood swings
4. Skin problems, such as acne or eczema
5. Nausea and vomiting
6. Weight loss or difficulty gaining weight
7. Difficulty walking or maintaining balance
8. Headaches or migraines
9. Muscle weakness or cramps
10. Seizures or convulsions (in severe cases)
Treatment of Vitamin B6 Deficiency:
1. Dietary changes: Increasing the intake of vitamin B6-rich foods, such as lean meats, whole grains, and vegetables, can help treat a deficiency.
2. Supplements: Taking a vitamin B6 supplement can help treat a deficiency. The recommended daily dose is 1.3-2.0 mg per day for adults.
3. Addressing underlying causes: If the deficiency is caused by an underlying medical condition, such as celiac disease or alcoholism, treating the condition can help resolve the deficiency.
4. Vitamin B complex supplements: Taking a vitamin B complex supplement that contains all eight B vitamins can help ensure that the body is getting enough of this essential nutrient.
In conclusion, vitamin B6 is an essential nutrient that plays a crucial role in many bodily functions. Deficiency in this vitamin can lead to a range of health problems, from mild discomforts like fatigue and nausea to more severe conditions like seizures and convulsions. Treatment of a deficiency typically involves dietary changes, supplements, and addressing any underlying medical conditions. It is important to seek medical advice if symptoms persist or worsen over time.
1. Irregular menstrual cycles, or amenorrhea (the absence of periods).
2. Cysts on the ovaries, which are fluid-filled sacs that can be detected by ultrasound.
3. Elevated levels of androgens (male hormones) in the body, which can cause a range of symptoms including acne, excessive hair growth, and male pattern baldness.
4. Insulin resistance, which is a condition in which the body's cells do not respond properly to insulin, leading to high blood sugar levels.
PCOS is a complex disorder, and there is no single cause. However, genetics, hormonal imbalances, and insulin resistance are thought to play a role in its development. It is estimated that 5-10% of women of childbearing age have PCOS, making it one of the most common endocrine disorders affecting women.
There are several symptoms of PCOS, including:
1. Irregular menstrual cycles or amenorrhea
2. Weight gain or obesity
3. Acne
4. Excessive hair growth on the face, chest, and back
5. Male pattern baldness
6. Infertility or difficulty getting pregnant
7. Mood changes, such as depression and anxiety
8. Sleep apnea
PCOS can be diagnosed through a combination of physical examination, medical history, and laboratory tests, including:
1. Pelvic exam: A doctor will examine the ovaries and uterus to look for cysts or other abnormalities.
2. Ultrasound: An ultrasound can be used to detect cysts on the ovaries and to evaluate the thickness of the uterine lining.
3. Hormone testing: Blood tests can be used to measure levels of androgens, estrogen, and progesterone.
4. Glucose tolerance test: This test is used to check for insulin resistance, which is a common finding in women with PCOS.
5. Laparoscopy: A small camera inserted through a small incision in the abdomen can be used to visualize the ovaries and uterus and to diagnose PCOS.
There is no cure for PCOS, but it can be managed with lifestyle changes and medication. Treatment options include:
1. Weight loss: Losing weight can improve insulin sensitivity and reduce androgen levels.
2. Hormonal birth control: Birth control pills or other hormonal contraceptives can help regulate menstrual cycles and reduce androgen levels.
3. Fertility medications: Clomiphene citrate and letrozole are commonly used to stimulate ovulation in women with PCOS.
4. Injectable fertility medications: Gonadotropins, such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH), can be used to stimulate ovulation.
5. Surgery: Laparoscopic ovarian drilling or laser surgery can improve ovulation and fertility in women with PCOS.
6. Assisted reproductive technology (ART): In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) can be used to help women with PCOS conceive.
7. Alternative therapies: Some complementary and alternative therapies, such as acupuncture and herbal supplements, may be helpful in managing symptoms of PCOS.
It is important for women with PCOS to work closely with their healthcare provider to develop a treatment plan that meets their individual needs and goals. With appropriate treatment, many women with PCOS can improve their menstrual regularity, fertility, and overall health.
Combined oral contraceptive pill
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Contraceptive rights in New Zealand
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Contraceptives, Oral, Combined - PubMed
Combined oral contraceptive pill eases painful periods
Use of combined oral contraceptives: retrospective study in Isfahan, Islamic Republic of Iran
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COCs8
- Combined oral contraceptives (COCs) are widely used in women of reproductive age in the United States. (aspetjournals.org)
- We carried out a retrospective cross-sectional study on 500 women in Isfahan who started taking combined oral contraceptives [āCOCs]ā during the period 21 March 1995-20 March 1997. (who.int)
- It has been recognized for over 50 years that combined oral contraceptives (COCs) are also capable of offering health benefits beyond contraception through the treatment and prevention of several gynaecological and medical disorders. (minervamedica.it)
- During the last years a constant attention was given to the adverse effects of COCs, whereas their non-contraceptive benefits were underestimated. (minervamedica.it)
- Using COCs specifically for non-contraceptive indications is still outside the product licence in the majority of cases. (minervamedica.it)
- Although considerable work has been done on contraceptives in the Islamic Republic of Iran, little is known about the continuation rate of combined oral contraceptives (COCs) and problems concerning their use. (who.int)
- Do combined oral contraceptives (COCs) affect breastfeeding or infant outcomes? (cfpclearn.ca)
- The use of combined oral contraceptives (COCs) is associated with approximately 2-fold and over 4-fold increased relative risks. (nel.edu)
Hormonal contraceptives3
- To date, most women are still unaware of the therapeutic uses of hormonal contraceptives, while on the contrary there is an extensive and constantly increasing of these non-contraceptive health benefits. (minervamedica.it)
- Family medical history, genetics, weight, high blood pressure and cholesterol levels , and chemical imbalances from use of hormonal contraceptives are among the possible explanations for these associations, according to study author Krishnarajah Nirantharakumar, a senior clinical lecturer at the University of Birmingham in the United Kingdom, and colleagues. (medicinenet.com)
- This type of medication is widely used, with more than 3 million women currently using hormonal contraceptives in the UK alone. (121doc.com)
Estrogen5
- Or combined pills with both progestin and estrogen. (feministpeacenetwork.org)
- The most common type of BCP combines the hormones estrogen and progestin . (medlineplus.gov)
- The World Health Organization listed combined (estrogen plus progestin) oral contraceptives and combined hormone replacement therapy as "Group 1 carcinogens" in July 2005. (conservapedia.com)
- A combined oral contraceptive pill contains a formulation of the hormones progesterone and estrogen. (asu.edu)
- the consumption of animal fat and protein (7) and alcohol (8), nonbreastfeeding (9), and use of oral contraceptives (10) and estrogen replacement therapy (11) have all been suggested. (cdc.gov)
Contraception4
- Women who discontinue oral contraception often substitute a less reliable method or no method at all, often leading to unintended pregnancy. (who.int)
- If you take your first Femodette pill between day two and day five of your period, you will need to use an alternative contraceptive method for seven days (such as barrier contraception). (121doc.com)
- In recent years, a growing number of companies providing contraception through online platforms ("telecontraception") have entered the market and are providing a new option for people to conveniently obtain contraceptive supplies that need a prescription without the need for an in-person visit. (kff.org)
- Organization (WHO)1 emphasized the importance freely distributed inclusive among the of the emergency contraception in the prevention adolescents3, once this public group shows of unplanned pregnancies and therefore abortions, maturity, evolution of psychological patterns, as the only contraceptive method for post-coital use. (bvsalud.org)
Vaginal contraceptive2
- NuvaRing is a vaginal contraceptive ring. (healthline.com)
- The authors enrolled patients in the study who were new users of either a vaginal contraceptive ring known as NuvaRing or a combined oral contraceptive pill. (asu.edu)
Pregnancy5
- It is important to know that pregnancy also increases the risk for blood clots, and much more significantly than any hormonal contraceptive. (mountsinai.org)
- Contraceptives are devices, drugs, or methods for preventing pregnancy either by preventing the fertilization of the female egg by the male sperm or by preventing implantation of the fertilized egg. (mountsinai.org)
- To systematically review, summarize and assess all relevant evidence on whether the provision of a wide choice of modern contraceptive methods is associated with improved health outcomes (intermediate and ultimate) including: uptake, acceptability, adherence, continuation, satisfaction, reduction of unintended pregnancy, improved maternal health and wellbeing. (who.int)
- Femodette is a contraceptive pill that is almost 100% effective at preventing pregnancy. (121doc.com)
- This contraceptive, popularly known as "the from the dependent child life to the adult morning-after pill," is effective in preventing independence4, factors that often lead to the pregnancy in 98% of the cases (if used within 24 practice of unprotected sex5. (bvsalud.org)
Intrauterine2
- The American Academy of Pediatrics and the American College of Obstetricians and Gynecologists (ACOG) recommend intrauterine devices (IUDs) and contraceptive implants (Nexplanon) as first-line contraceptive options for sexually active teens based on the effectiveness of these contraceptives and high rates of patient satisfaction. (mountsinai.org)
- Intrauterine contraceptive device: these are also called "coils" and are inserted into the womb, usually at the time of a smear. (rbht.nhs.uk)
Pill11
- Washington, Jan 18 (ANI): After a 30-year-long study, scientist have finally provided convincing evidence that the combined oral contraceptive pill does, indeed, alleviate the symptoms of painful menstrual periods - dysmenorrhoea. (newstrackindia.com)
- Although some previous studies and anecdotal evidence have suggested that the combined oral contraceptive pill could have an impact on painful periods, a 2009 review of all the available research by the prestigious Cochrane Collaboration concluded that there was limited evidence for pain improvement. (newstrackindia.com)
- Now, Dr Ingela Lindh and her colleagues at the Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University, Sweden, found that women who used the combined oral contraceptive pill suffered less severe pain compared with women who did not use it. (newstrackindia.com)
- If you are extra cautious, taking an oral contraceptive pill daily should be included in your routine. (feministpeacenetwork.org)
- Women of all ages can now get the levonorgestrel emergency contraceptive pill Plan B One-Step and its generic versions without a prescription. (mountsinai.org)
- BCPs are also called oral contraceptives or just "the pill. (medlineplus.gov)
- The presence of both these female sex hormones make Femodette a combined contraceptive pill. (121doc.com)
- Femodette is suitable for women who are over the age of 18 and who want to use a combined contraceptive pill to prevent conception. (121doc.com)
- This makes the contraceptive pill one of the safest and most researched prescription treatments available. (121doc.com)
- This is a monophasic contraceptive treatment, meaning that each individual Femodette pill contains the same combination of hormones. (121doc.com)
- Femodette is a popular contraceptive pill that is both well researched and widely used. (121doc.com)
Venous thromboembolism2
- However, some WHO recommendations were modified for use in the United States, including recommendations about contraceptive use for women with venous thromboembolism, valvular heart disease, ovarian cancer, and uterine fibroids and for postpartum and breastfeeding women. (cdc.gov)
- Venous thromboembolism (VTE) is a multifactorial disease driven by environmental/acquired risk factors such as age, obesity, oral contraceptives, and immobility, as well as inherited risk factors such as genetic polymorphisms. (medscape.com)
Pills1
- They can be found in several female contraceptive pills, specifically to reduce hirstuitism, which may result from medical conditions such as hormone imbalance or Polycystic Ovary syndrome. (susans.org)
World Health Organ2
- CDC created U.S. Medical Eligibility Criteria for Contraceptive Use, 2010, from guidance developed by the World Health Organization (WHO) and finalized the recommendations after consultation with a group of health professionals who met in Atlanta, Georgia, during February 2009. (cdc.gov)
- In 1996, the World Health Organization (WHO) published the first edition of the Medical Eligibility Criteria for Contraceptive Use (MEC), which gave evidence-based guidance on the safety of contraceptive method use for women and men worldwide who had specific characteristics and medical conditions. (cdc.gov)
Hormone2
- Potential non-surgical therapies include pain medication combined with hormone therapy, as noted by Mayo Clinic . (thelist.com)
- One example of a hormone therapy for endometriosis is oral contraceptives, which have been shown to be effective for some women at helping with pain symptoms. (thelist.com)
Discontinuation1
- Side-effects of oral contraceptives were the most frequent reasons given by women for discontinuation of use [6]. (who.int)
Progesterone2
- There was no association between heart disease risk and current use of progesterone -only contraceptives, use of non-oral hormonal contraceptive agents or fertility treatment, the study authors noted. (medicinenet.com)
- The patient was diagnosed after a positive response to an intradermal test with progesterone and was successfully treated with combined oral contraceptives. (thieme-connect.com)
Adolescents1
- Cases of sexual violence are fundamentally attended to, but excluding these cases, there is a drop of 10 to 30 percentage points in the distribution of emergency contraceptive to adolescents in cases of the failure or non-use of the regular contraceptive. (bvsalud.org)
Women10
- Each group included approximately 400 to 520 women, who provided information on their height, weight, reproductive history, pattern of menstruation and menstrual pain, and contraceptive use. (newstrackindia.com)
- We found there was a significant difference in the severity of dysmenorrhoea depending on whether or not the women used combined oral contraceptives," said Dr Lindh, who is also a registered nurse and midwife. (newstrackindia.com)
- This guidance comprises recommendations for the use of specific contraceptive methods by women and men who have certain characteristics or medical conditions. (cdc.gov)
- The recommendations in this document are intended to assist health-care providers when they counsel women, men, and couples about contraceptive method choice. (cdc.gov)
- This document contains recommendations for health-care providers for the safe use of contraceptive methods by women and men with various characteristics and medical conditions. (cdc.gov)
- Consider an alternate contraceptive method for women with uncontrolled dyslipidemia. (nih.gov)
- This three-stage approach makes Femodette one of the most effective contraceptive methods available to women. (121doc.com)
- It is estimated that over 100 million women are currently using oral contraceptive medication in the world today. (121doc.com)
- One study focused on characteristics of patients seeking services through one telecontraception platform and found that women ages 18-24 and 25-34 make up the majority of telecontraception users and that combined oral contraceptives were the most dispensed contraceptives. (kff.org)
- The share of women nationally that relies on these companies to obtain contraceptives is still relatively small. (kff.org)
Implant1
- Just like a contraceptive implant, IUD is reversible. (feministpeacenetwork.org)
Methods10
- However, several changes have been made, including adaptations of selected WHO recommendations, addition of recommendations for new medical conditions, and removal of recommendations for contraceptive methods not currently available in the United States ( Appendix A ). (cdc.gov)
- As well as being able to tell you how your condition can affect the contraceptive you take, they can advise you what methods are most suited to you. (rbht.nhs.uk)
- The suitability of different contraceptive methods may depend on other illnesses that you have, the medicines that you are taking, and your own personal preference. (rbht.nhs.uk)
- 5.1 Does a policy of providing a wide range of contraceptive methods, as opposed to the provision of a limited range, improve contraceptive uptake? (who.int)
- 5.2 Does a policy of providing a wide range of contraceptive methods, as opposed to the provision of a limited range, improve contraceptive acceptability/satisfaction, and hence adherence/continuation? (who.int)
- 5.3 Does a policy of providing a wide range of contraceptive methods, as opposed to the provision of a limited range, improve maternal health and well-being (including the reduction of unintended pregnancies)? (who.int)
- To identify a minimum optimal range of contraceptive methods to be made available. (who.int)
- Head-to-head randomised and non-randomised comparison studies on the effectiveness, safety, uptake, acceptability, adherence and continuation of different contraceptive methods. (who.int)
- Over the past year, companies have expanded to offer the newest contraceptive methods like Annovera, the one-year ring, and services like acne treatment and anxiety medication. (kff.org)
- 9. Consent of study participants to use effective contraceptive methods throughout their participation in the study. (who.int)
Cardiovascular4
- Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. (nih.gov)
- Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC) use. (nih.gov)
- Cardiovascular risk and the use of oral contraceptives. (nel.edu)
- Kaminski P, Szpotanska-Sikorska M, Wielgos M. Cardiovascular risk and the use of oral contraceptives. (nel.edu)
Method1
- Continuation rates are reliable indicators of the overall use of a contraceptive method. (who.int)
Outcomes1
- Observational studies on the introduction of a variety of contraceptives which measure health outcomes and/or uptake, acceptability, adherence and continuation or similar parameters. (who.int)
Choosing1
- Choosing the appropriate contraceptive is a personal decision. (mountsinai.org)
Reversible1
- The effects are reversible and there are many non-contraceptive health benefits, some of which last for years [3]. (who.int)
Sexually1
- Some of these companies specialize in contraceptive care and others have expanded services into sexually transmitted infection (STI) testing and treatment, as well as other primary healthcare services. (kff.org)
Cholera vaccine4
- Do not administer cholera vaccine to patients who have received oral or parenteral antibiotics within 14 days prior to vaccination. (medscape.com)
- Data from an older formulation of the CVD 103-HgR oral cholera vaccine suggest that the immune response to the vaccine might be diminished when given concomitantly with chloroquine. (cdc.gov)
- Administer live attenuated oral cholera vaccine ā„10 days before beginning antimalarial prophylaxis with chloroquine. (cdc.gov)
- A study in children using oral cholera vaccine suggested no decrease in immunogenicity when given with atovaquone-proguanil. (cdc.gov)
Reproductive1
- This position is due in part to health care professionals not being up to date on the laws and federal norms concerning Sexual and Reproductive Health, and also to the lack of knowledge of the method's mechanism action (sometimes identified as dangerous or abortive), as well as the prejudice towards adolescent sexual practices- leading to the purchasing of emergency contraceptive in drugstores and its incorrect use. (bvsalud.org)
Risk2
- Describe the effects of oral contraceptives on the risk for ovarian cancer. (medscape.com)
- Risk conferred by genetic variants may be magnified when combined with acquired risk factors. (medscape.com)
Effective1
- Is ritonavir-boosted nirmatrelvir (PaxlovidĀ®) a safe and effective oral therapy for the treatment of COVID-19? (cfpclearn.ca)
Genetic1
- Use of combined oral contraceptives alters metabolic determinants and genetic regulation of C-reactive protein. (bvsalud.org)
Efficacy1
- To assess the efficacy of combined mammography and physical breast examination in reducing breast cancer mortality, a large randomized clinical trial was conducted at the Health Insurance Plan in New York City in the mid-1960s (14). (cdc.gov)
Parenteral1
- Parenteral typhoid vaccine is an alternative to the oral typhoid vaccine for travelers who have recently received antibiotics. (cdc.gov)
Found1
- We found that combined oral contraceptive use reduced dysmenorrhoea by 0.3 units, which means that every third woman went one step down on the VMS scale, for instance from severe pain to moderate pain, and which meant that they suffered less pain, improved their working ability and there was a decrease in the need for analgesics. (newstrackindia.com)
Recommendations2
- CDC, through close collaboration with WHO, has contributed substantially during the last 15 years to creation of WHO's global family planning guidance, which includes four documents: the medical eligibility criteria for contraceptive use, the selected practice recommendations for contraceptive use, a decision-making tool for clients and providers, and a global family planning handbook. (cdc.gov)
- Recommendations for updating selected practices in contraceptive use : results of a technical meeting / editors, Kathryn M. Curtis and Patricia L. Bright. (who.int)
Agents1
- Antimicrobial agents can be active against the vaccine strains in the oral typhoid and cholera vaccines and might prevent adequate immune response to these vaccines. (cdc.gov)
Product2
- Reports, opinion papers and position papers from contraceptive service suppliers/product distributors. (who.int)
- The hydrogen peroxide combines with 4-chlorophenol under the action of peroxidase to produce an oxidation product that that does not react with the colorometric component of reagent 2. (cdc.gov)
Alternative1
- The use of novel oral anticoagulants, including dabigatran, rivaroxaban, and apixaban, is not expected to cause significant interactions, and their use has been suggested as an alternative for patients in need of anticoagulation. (cdc.gov)
ADMINISTRATION1
- Ibrutinib will be supplied by Pharmacyclics as 140 mg hard gelatin capsules for oral (PO) administration. (clinicaltrials.gov)