Contraception
Contraception, Postcoital
Contraceptives, Postcoital
Contraceptive Agents, Female
Contraceptives, Postcoital, Hormonal
Contraceptives, Oral, Hormonal
Contraceptive Agents, Male
Family Planning Services
Levonorgestrel
Contraceptive Devices
Contraceptives, Oral
Pregnancy, Unplanned
Contraceptives, Postcoital, Synthetic
Contraceptives, Oral, Combined
Contraception, Immunologic
Abortion, Induced
Sterilization, Reproductive
Intrauterine Devices, Copper
Contraception, Barrier
Pregnancy
Desogestrel
Ovulation Inhibition
Health Knowledge, Attitudes, Practice
Medroxyprogesterone Acetate
Reproductive Health Services
Norgestrel
Sex Education
Transdermal Patch
Contraceptives, Oral, Synthetic
Abortion, Legal
Spermatogenesis-Blocking Agents
Norethindrone
A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.
Norpregnadienes
Reproductive Medicine
A medical-surgical specialty concerned with the morphology, physiology, biochemistry, and pathology of reproduction in man and other animals, and on the biological, medical, and veterinary problems of fertility and lactation. It includes ovulation induction, diagnosis of infertility and recurrent pregnancy loss, and assisted reproductive technologies such as embryo transfer, in vitro fertilization, and intrafallopian transfer of zygotes. (From Infertility and Reproductive Medicine Clinics of North America, Foreword 1990; Journal of Reproduction and Fertility, Notice to Contributors, Jan 1979)
Progestins
Drug Implants
Spermatocidal Agents
Gynecology
Ethinyl Estradiol
Sterilization, Tubal
Fertility
Norprogesterones
Condoms
Vasectomy
Uterine Hemorrhage
Family Planning Policy
Questionnaires
Pregnanediol
Menstruation
Emergencies
Conscience
Mifepristone
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Ambulatory Care Facilities
Sexuality
Chlormadinone Acetate
Antispermatogenic Agents
Sex Counseling
Parity
Mestranol
Catholicism
The Christian faith, practice, or system of the Catholic Church, specifically the Roman Catholic, the Christian church that is characterized by a hierarchic structure of bishops and priests in which doctrinal and disciplinary authority are dependent upon apostolic succession, with the pope as head of the episcopal college. (From Webster, 3d ed; American Heritage Dictionary, 2d college ed)
Cross-Sectional Studies
Health Services Accessibility
Progesterone Congeners
Ethinyl Estradiol-Norgestrel Combination
Population Control
Women's Health Services
Spermatogenesis
Menstrual Cycle
The period from onset of one menstrual bleeding (MENSTRUATION) to the next in an ovulating woman or female primate. The menstrual cycle is regulated by endocrine interactions of the HYPOTHALAMUS; the PITUITARY GLAND; the ovaries; and the genital tract. The menstrual cycle is divided by OVULATION into two phases. Based on the endocrine status of the OVARY, there is a FOLLICULAR PHASE and a LUTEAL PHASE. Based on the response in the ENDOMETRIUM, the menstrual cycle is divided into a proliferative and a secretory phase.
United Arab Emirates
A federation of seven states on the southeast portion of the Arabian peninsula: Abu Dhabi, Ajman, Dubai, Fujairah, Ras al-Khaimah, Sharjah and Umm al-Qaiwain. In 1820 a treaty of peace was concluded between Great Britain and native rulers. During the 19th century the rulers agreed to suppression of the slave trade and restriction of foreign relations to Great Britain. The Trucial Council was established in 1952 and defense treaties with Great Britain terminated. In 1971 an independent six-member federation was formed, with Ras al-Khaimah joining the federation in 1972. (From Webster's New Geographical Dictionary, 1988, p1250)
Reproductive Physiological Phenomena
Marriage
Directive Counseling
Lipid Metabolism Disorders
Delayed-Action Preparations
Adolescent Health Services
Prescriptions
Gynecological Examination
Obstetrics
Health Care Surveys
Abortion, Therapeutic
Socioeconomic Factors
Pregnancy Rate
Nonoxynol
Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.
Armenia
An ancient country in western Asia, by the twentieth century divided among the former USSR, Turkey, and Iran. It was attacked at various times from before the 7th century B.C. to 69 B.C. by Assyrians, Medes, Persians, the Greeks under Alexander, and the Romans. It changed hands frequently in wars between Neo-Persian and Roman Empires from the 3d to 7th centuries and later under Arabs, Seljuks, Byzantines, and Mongols. In the 19th century Armenian nationalism arose but suffered during Russo-Turkish hostilities. It became part of the Soviet Republic in 1921, with part remaining under Turkey. (Webster's New Geographical Dictionary, 1988)
Uterine Perforation
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Preconception Care
An organized and comprehensive program of health care that identifies and reduces a woman's reproductive risks before conception through risk assessment, health promotion, and interventions. Preconception care programs may be designed to include the male partner in providing counseling and educational information in preparation for fatherhood, such as genetic counseling and testing, financial and family planning, etc. This concept is different from PRENATAL CARE, which occurs during pregnancy.
Interviews as Topic
Netherlands Antilles
Former Netherlands overseas territory in the Lesser Antilles in the West Indies. It had included the islands of Aruba, Bonaire, Curacao, Saba, St. Eustatius, and the southern part of St. Martin. The Netherlands Antilles dissolved on October 10, 2010. Aruba, Curacao and Sint Maarten became autonomous territories of the Kingdom of the Netherlands. Bonaire, Saba, and Sint Eustatius are under the direct administration of the Netherlands. (From US Department of State, Background Note)
Logistic Models
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Bosnia-Herzegovina
A country of eastern Europe, formerly the province of Bosnia in Yugoslavia, uniting with the province of Herzegovina to form the Republic of Bosnia and Herzegovina in 1946. It was created 7 April 1992 as a result of the division of Yugoslavia and recognized by the United States as an independent state. Bosnia takes is name from the river Bosna, in turn from the Indoeuropean root bhog, "current"; Herzegovina is from the Serbian herceg (duke) + -ov (the possessive) + -ina (country or territory).
Emergency Treatment
Nursing Records
Intrauterine Device Migration
Attitude
Female Urogenital Diseases
Paternalism
Interference with the FREEDOM or PERSONAL AUTONOMY of another person, with justifications referring to the promotion of the person's good or the prevention of harm to the person. (from Cambridge Dictionary of Philosophy, 1995); more generally, not allowing a person to make decisions on his or her own behalf.
Health Surveys
Safe Sex
Choice Behavior
Religion
A set of beliefs concerning the nature, cause, and purpose of the universe, especially when considered as the creation of a superhuman agency. It usually involves devotional and ritual observances and often a moral code for the conduct of human affairs. (Random House Collegiate Dictionary, rev. ed.)
Menstruation-Inducing Agents
Ethiopia
Adolescent Medicine
Forensic Nursing
The application of NURSING knowledge to questions of law. It is a specialty of nursing practice involving victims of crime which includes not only attending to the physical and emotional distress of victims, but also the identifying, collecting, and preserving evidence for law enforcement and the criminal justice system.
Nigeria
Danazol
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Risk Factors
Testosterone
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Prospective Studies
Physicians, Primary Care
Attitude of Health Personnel
Adolescent Psychology
Health Education
Population Growth
Spermatozoa
Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.
HIV Infections
Fertile Period
The period in the MENSTRUAL CYCLE that is optimal for FERTILIZATION of the OVUM and yielding PREGNANCY. The duration of fertile period depends on the life span of male GAMETES within the female reproductive tract and the time of OVULATION. It usually begins a few days before ovulation and ends on the day of ovulation.
Marital Status
Legislation, Pharmacy
Risk-Taking
Mythology
Data Collection
Acne Vulgaris
Natural Family Planning Methods
A class of natural contraceptive methods in which SEXUAL ABSTINENCE is practiced a few days before and after the estimated day of ovulation, during the fertile phase. Methods for determining the fertile period or OVULATION DETECTION are based on various physiological indicators, such as circulating hormones, changes in cervical mucus (CERVIX MUCUS), and the basal body temperature.
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Family Practice
Outpatient Clinics, Hospital
Health Services Needs and Demand
Fetal Alcohol Spectrum Disorders
An umbrella term used to describe a pattern of disabilities and abnormalities that result from fetal exposure to ETHANOL during pregnancy. It encompasses a phenotypic range that can vary greatly between individuals, but reliably includes one or more of the following: characteristic facial dysmorphism, FETAL GROWTH RETARDATION, central nervous system abnormalities, cognitive and/or behavioral dysfunction, BIRTH DEFECTS. The level of maternal alcohol consumption does not necessarily correlate directly with disease severity.
Physician's Practice Patterns
Multivariate Analysis
Kenya
Community Pharmacy Services
Unsafe Sex
Abnormalities, Drug-Induced
Progesterone
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
Abortion, Spontaneous
A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida. (1/106)
In this study, we have mapped and characterized a B cell epitope of sulfated glycoprotein ZP2 (ZP2) as a step toward the development of a multi-epitope zona pellucida (ZP) vaccine. Recombinant polypeptides expressed by random deoxyribonuclease-digested fragments of ZP2 cDNA were screened for binding to IE-3, a monoclonal antibody to murine ZP2. Positive clones contained cDNA inserts encoding polypeptide corresponding to ZP2(103-134). When normal or ovariectomized female mice were immunized with three overlapping peptides that span this region of ZP2 (101-120, 111-130, 121-140), only ZP2(121-140) elicited IgG antibodies that reacted with mouse ovarian ZP, indicative of the presence of native B epitope and helper T cell epitope in ZP2(121-140). To more finely map the ZP2 B cell epitope, a random peptide display library was screened with the IE-3 antibody, and a consensus tetramer sequence VxYK that matched the ZP2(123-126) sequence VRYK was located. Competitive immunofluorescence analysis with single alanine-substituted VxYK peptides ranked the relative contribution of the three critical B cell epitope residues as Y > V > K. A chimeric peptide was constructed that contained the YRYK motif of ZP2 and a bovine RNase T cell epitope. Although (C57BL/6xA/J) F1 (B6AF1) female mice immunized with the chimeric peptide developed ZP antibody response, this peptide elicited antibody only in mice of the histocompatibility complex (MHC) H-2(k or b) haplotype. In contrast, ZP2(121-140) peptide elicited antibody in inbred mice with three additional mouse MHC haplotypes. Moreover, although ZP2(121-140) contained a T cell epitope, no oophoritis was observed after immunization of B6AF1 mice with ZP2(121-140) in complete Freund's adjuvant (CFA). In a preliminary trial, female B6AF1 mice immunized with ZP2(121-140) in CFA had reduced litter sizes as compared with mice injected with CFA alone. (+info)Antibodies to human ZP3 induce reversible contraception in transgenic mice with 'humanized' zonae pellucidae. (2/106)
The initial spermatozoon-egg interaction of mammalian fertilization is mediated by the zona pellucida, an extracellular matrix composed of three glycoproteins (ZP1, ZP2, ZP3). These proteins are sufficiently conserved between human and mouse to form chimeric zonae pellucidae, and genetically engineered mice in which the endogenous mouse ZP3 has been replaced by human ZP3 have 'humanized' zonae, but normal fertility. Administration of monoclonal antibodies to mouse ZP3 does not affect fertility in these animals, but administration of antibodies to human ZP3 results in long-term, reversible contraception. The antibodies coat the zonae pellucidae surrounding growing oocytes within the ovary and their presence in the zona matrix inhibits, but does not eliminate, sperm binding. The contraceptive effect is attributed to steric hindrance that decreases sperm binding and prevents penetration through the zona pellucida. The resumption of fertility is associated with the disappearance of antibodies from the zona matrix. No adverse effect on mating behaviour, ovarian histology or fetal development (if administered after fertilization) is detected in treated females. These results suggest that transgenic mice expressing human proteins will prove useful in assessing contraceptive efficacy of zona epitopes in the rational design of immunocontraception directed at the human zona pellucida. (+info)Design and evaluation of a ZP3 peptide vaccine in a homologous primate model. (3/106)
The concept of a safe, immunocontraceptive vaccine using the zona pellucida glycoprotein 3 (ZP3) as an immunogen has been marred by the appearance of ovarian dysfunction in several species. However, careful selection of epitopes on mouse ZP3 have demonstrated that it is possible to segregate contraceptive bone marrow-derived (B)-cell epitopes from the cytotoxic thymus-derived (T)-cell epitopes thought to be responsible for inducing ovarian disease. B-cell epitopes on marmoset ZP3 (mstZP3) were identified by epitope mapping studies. Using a panel of polyclonal antibodies against recombinant mstZP3, an immunodominant epitope mstZP3(301-320) was identified. A chimeric peptide was co-linearly synthesized incorporating this sequence with a promiscuous tetanus toxoid T-helper cell epitope. Using the common marmoset (Callithrix jacchus) as an animal model, we have compared the consequences of active immunization with homologous recombinant mstZP3 and mstZP3(301-320) chimeric peptide vaccine. Long-term infertility was achieved using mstZP3 but at the expense of ovarian function. In contrast, no disruption to ovarian function was observed following mstZP3(301-320) immunization. Antibodies to this peptide immunolocalized to the zona pellucida of both marmoset and human ovarian sections and inhibited human sperm-zona binding by approximately 60% in vitro. However, in-vivo studies indicated that targeting a single ZP3 epitope was insufficient to reliably and consistently achieve a contraceptive effect. (+info)Antigenic and immunogenic properties of totally synthetic peptide-based anti-fertility vaccines. (4/106)
In this study we describe the results of experiments in which a variety of totally synthetic luteinizing hormone releasing hormone (LHRH) vaccines were assembled and examined for their abilities to elicit antibody responses and induce sterility in mice. It is shown that totally synthetic vaccines consisting of a 15 residue-defined T cell epitope and the 10 residue LHRH epitope not only induced high titers of antibody but also induced sterility. This effect did not appear to correlate with antibody titer, antibody isotype or comparative antibody affinity, but may be related to the length of time for which antibodies are present to exert their influence. (+info)Immunological control of fertility: measurement of affinity of antibodies to human chorionic gonadotrophin. (5/106)
Four baboons were primed with diazotized beta human chorionic gonadotrophin and boosted with diazotized C-terminal beta human chorionic gonadotrophin peptide, and the changes in antibody amount and affinity determined using a double isotope modified Farr assay, using labelled human chorionic gonadotrophin as the antigen. The degree of cross-reaction with human luteinizing hormone was also determined. Although appreciable reactivity with luteinizing hormone was observed soon after immunization, this declined rapidly during the response. At the time intervals studied, there was a progressive increase in affinity of antibodies to human chorionic gonadotrophin until day 248 after priming. At day 313, in two of the animals, there was a decrease in affinity from 1.04 X 10(11) to 6.80 X 10(10) and 1.05 X 10(11) to 4.93 X 10(10) l/mol, whereas in the other two baboons there was a further increase in antibody affinity. At corresponding time intervals, there was a steady decrease in values of total antibody binding sites. To determine the overall effect of the maturation of affinity with a decrease in antibody amount on biological efficacy, the theoretical amount of chorionic gonadotrophin that would be neutralized was calculated. We computed that in all instances, over 99% of a peak concentration of chorionic gonadotrophin that could be in circulation in a pregnant baboon would be neutralized. This was in excellent agreement with results of mating experiments in these baboons. In over forty cycles studied, none of the matings resulted in a sustained pregnancy. (+info)Delineation of a conserved B cell epitope on bonnet monkey (Macaca radiata) and human zona pellucida glycoprotein-B by monoclonal antibodies demonstrating inhibition of sperm-egg binding. (6/106)
To circumvent autoimmune oophoritis after immunization with zona pellucida (ZP) glycoproteins, synthetic peptides encompassing B cell epitope(s) and devoid of oophoritogenic T cell epitopes as immunogens have been proposed. In this study, bonnet monkey (Macaca radiata) ZP glycoprotein-B (bmZPB) was expressed as polyhistidine fusion protein in Escherichia coli. Rabbit polyclonal antibodies against recombinant bmZPB (r-bmZPB) significantly inhibited human sperm-oocyte binding. To map B cell epitopes on ZPB, a panel of 7 murine monoclonal antibodies (mAbs) was generated against r-bmZPB. All 7 mAbs, when tested in an indirect immunofluorescence assay, reacted with bonnet monkey ZP, and only 6 recognized human zonae. Monoclonal antibodies MA-809, -811, -813, and -825 showed significant inhibition in the binding of human spermatozoa to human ZP in a hemizona assay. Epitope-mapping studies using multipin peptide synthesis strategy revealed that these 4 mAbs recognized a common epitope corresponding to amino acids (aa) 136-147 (DAPDTDWCDSIP). Competitive binding studies revealed that the synthetic peptide corresponding to the identified epitope (aa 136-147) inhibited the binding of MA-809, -811, -813, and -825 to r-bmZPB in an ELISA and to bonnet monkey ZP in an indirect immunofluorescence assay. The epitopic domain corresponding to aa 136-147 of bmZPB was completely conserved in human ZPB. These studies will further help in designing ZP-based synthetic peptide immunogens incorporating relevant B cell epitope for fertility regulation in humans. (+info)Identification of human sperm peptide sequence involved in egg binding for immunocontraception. (7/106)
Development of a vaccine based on sperm antigens represents a promising approach to contraception. The sperm-zona pellucida (ZP) interaction constitutes the most important event in the fertilization process, and the molecular sequences involved at this site may provide the most attractive candidates for immunocontraception. In the present study, using the phase peptide display technique, a novel dodecamer sequence, designated as YLP(12), was identified that is involved in sperm-ZP recognition/binding. The synthetic 12-mer peptide based on this sequence and its monovalent Fab' antibodies specifically and significantly (P < 0.05) inhibited human sperm-ZP binding. In Western blot and immunoprecipitation procedures, the YLP(12) peptide recognized the ZP3 component of solubilized human ZP proteins. In the Western blot procedure involving 10 different human tissue extracts, the anti-YLP(12) Fab' antibodies recognized a protein band of approximately 72 +/- 2 kDa only in the testis lane. The peptide sequence was localized on the acrosomal region of the human sperm cell. These findings indicate that the novel testis-specific 12-mer YLP(12) that is present in the acrosomal region and is involved in human sperm-ZP interaction may find applications in contraceptive vaccine development, as well as in diagnosis and treatment of male infertility mediated through sperm dysfunction. (+info)Immunological block to mammalian fertilization: survival and organ distribution of immunoglobulin which inhibits fertilization in vivo. (8/106)
Fertilization of golden hamster eggs was blocked both in vitro and in vivo by antibodies produced in rabbits against specific hamster ovarian antigens (HOA). Antibodies against HOA bound to surfaces of the hamster egg zona pellucida and prevented spermatozoa from attaching to the zona and entering eggs in vitro. Fertilization in animals could be blocked for four estrous cycles by a single intraperitoneal injection of anti-HOA immunoglobulin, but not by control immunoglobulin. The in vivo fate of anti-HOA immunoglobulin was analyzed by simultaneous injection of 125I-anti-HOA IgG and control 131I-IgG. Both anti-HOA IgG and control IgG appeared in a variety of organs (lung, kidney, spleen, liver, and uterus) shortly after injection, but disappeared rapidly with no detectable differences in organ half lives. However, in the ovary anti-HOA IgG (but not control IgG) persisted at high levels during the period of infertility. Quantitative precipitin analysis of organ homogenates indicated that a high percentage of anti-HOA IgG in the ovary (but not in the other organs tested) was immunologically indistinguishable from IgG indicating lack of radiolabel metabolism and reincorporation. The results are discussed in terms of the development of a specific immunological block to fertility. (+info)
Immunocontraception - Wikipedia
Biological control of vertebrate pests using virally vectored immunocontraception<...
IMMUNOCONTRACEPTION AND POSSIBLE APPLICATION IN WILDLIFE DAMAGE MANAGE by Lowell A. Miller
Conference Announcement
Devin Kazakoff talks to TCC about the Native PZP Immunocontraceptive - The Critical Cat
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Evaluation of a single-shot gonadotropin-releasing hormone (GnRH) immunocontraceptive vaccine in captive badgers | SpringerLink
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Diaphragm Construction
Sperm-associated antigen 1
Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, ...
Sperm-associated antigen 6
Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, ...
Sperm-associated antigen 8
Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, ...
List of MeSH codes (E02)
... contraception, barrier MeSH E02.875.194.300 - contraception, immunologic MeSH E02.875.194.540 - contraception, postcoital MeSH ... immunologic MeSH E02.095.520.450.440 - graft enhancement, immunologic MeSH E02.095.520.450.521 - lymphocyte depletion MeSH ...
Angioedema
Acquired angioedema (AAE) can be immunologic, nonimmunologic, or idiopathic. It is usually caused by allergy and occurs ... it can be exacerbated by pregnancy and use of hormonal contraception (exact frequency uncertain). It has been linked with ...
Library of Congress Classification:Class R -- Medicine
Immunologic diseases. Allergy 620-627.........................................Nutritional diseases. Deficiency diseases 627.5- ... Contraception 138.........................................Sterilization of women 159-208................................... ...
Pregnancy test
Contraception. 95 (5): 442-448. doi:10.1016/j.contraception.2016.12.004. ISSN 0010-7824. PMID 28041991. Lynd, Kelsey; Blum, ... Immunologic pregnancy tests were introduced in 1960 when Wide and Gemzell presented a test based on in-vitro hemagglutination ... Contraception. 98 (1): 30-35. doi:10.1016/j.contraception.2018.03.013. ISSN 0010-7824. PMID 29534996. S2CID 206967147. Raymond ... Museum of Contraception and Abortion". en.muvs.org. Retrieved 29 March 2018. Bleavins MR, Carini C, Malle JR, Rahbari R (2010 ...
HIV Prevention Trials Network
HVTN 804/HPTN 095 is an antiretroviral analytical treatment interruption study to assess immunologic and virologic responses in ... and delivery systems for HIV prevention Developing multi-purpose technologies for HIV prevention as well as for contraception ... HVTN 805/HPTN 093 is an antiretroviral analytical treatment interruption study to assess immunologic and virologic responses in ...
Xenotransplantation
Takahashi, T.; Saadi, S.; Platt, J. L. (1997). "Recent advances in the immunology of xenotransplantation". Immunologic Research ... "the use of barrier contraception when engaging in sexual intercourse;" fifth, keep both name and current address on register ...
Adverse effect
Due to the exceedingly high impact on public health of widely used medications, such as hormonal contraception and hormone ... "Silicone Breast Implants in Relation to Connective Tissue Diseases and Immunologic Dysfunction". Archived from the original on ... Liver damage from paracetamol Melasma and thrombosis associated with use of estrogen-containing hormonal contraception, such as ...
Browsing by Subject "Contraception, Immunologic"
Results of search for 'su:{Contraception, Immunologic.}' › WHO HQ Library catalog
Browsing by Subject
Public Health Service Task Force Recommendations for the Use of
Antiretroviral Drugs in Pregnant Women Infected with HIV-1 for...
Data from follow-up of PACTG 076 infants from birth through age 18-36 months do not indicate any differences in immunologic, ... services that continue after pregnancy for their own medical care and for assistance with family planning and contraception. ... Such considerations include gestational age of the fetus; the womans clinical, immunologic, and virologic status; and the ... HIV-1-infected pregnant women must receive standard clinical, immunologic, and virologic evaluation. Recommendations for ...
Chronic Sinusitis: Practice Essentials, Background, Anatomy
Targeting Carcinoembryonic Antigen with DNA Vaccination: On-Target Adverse Events Link with Immunologic and Clinical Outcomes |...
... and adequate contraception in place. Patients with radiologically measurable metastatic disease after exhaustion of standard ... Immunologic evaluation. Immunologic responses were assessed using validated assays (34-36); T-cell responses were reported to ... Targeting Carcinoembryonic Antigen with DNA Vaccination: On-Target Adverse Events Link with Immunologic and Clinical Outcomes ... This in turn linked to immunologic and clinical outcomes, in particular, to transient decreases in CEA that allowed the ...
Interferon Alfa Following Surgery in Treating Patients With Stage III Melanoma - Full Text View - ClinicalTrials.gov
DeCS
Contraception, Immunologic Entry term(s). Contraception, Immunological Immunocontraception Immunologic Contraception ... Immunologic Contraception. Immunological Contraception. Immunological Contraceptive Technic. Immunological Contraceptive ... Contraception, Immunologic - Preferred Concept UI. M0005097. Scope note. Contraceptive methods based on immunological processes ... Contraception, Immunological. Contraceptive Technic, Immunological. Contraceptive Technics, Immunological. Contraceptive ...
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Contraception, Contraception, Immunologic, Climacteric, Hormone Replacement Therapy, Menopause, Estrogen Replacement Therapy, ... Immunologic Techniques, Immunotherapy, Physiology, Lecture, Schools, Nursing, Health of the Elderly, Geriatric Nursing, ... Immunologic Techniques, Molecular Biology, 37643, Genetic Techniques, Genetics, Genetic Diseases, Inborn, Genetics, Medical, ... Immunologic Techniques, Immunotherapy, Physiology, Chronic Disease, Lecture, Clinical Oncology = Oncologia, ...
IMSEAR at SEARO: Search
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The rhythm method and embryonic death | Journal of Medical Ethics
Oral contraception is intent merely on stopping the reproductive function, period. It has also been known to be abortifacient, ... Other factors contributing to early embryonic loss include uterine abnormalities, immunologic disorders, bleeding disorders, ... It seems possible that the child who was conceived at time A might have been conceived at time A even had the contraception not ... Contraception works to block, suppress, or destroy fertility -- actions that are contra fertility and, at times contra life. ...
Cyclosporine and Reperfusion Injury in AMI
Vaccine Plus Montanide ISA-51 and Sargramostim in Treating Patients With Stage IV Breast Cancer
These highlights do not include all the information needed to use RITUXAN safely and effectively. See full prescribing...
Advise female patients that rituximab can cause fetal harm if taken during pregnancy and to use effective contraception during ... The B-cell counts returned to normal levels, and immunologic function was restored within 6 months postpartum. ... Females who are able to become pregnant should use effective birth control (contraception) during treatment with RITUXAN and ... Females of childbearing potential should use effective contraception while receiving RITUXAN and for 12 months following the ...
Proctitis
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Pesquisa | Portal Regional da BVS
... also used condoms or emergency contraception, and 9% also used hormonal contraception or sterilization. An FABM was the most ... Limited clinical data suggest changes in immunologic activity following DMPA-IM and NET-EN initiation, but interstudy variation ... One-third of 15-24 year-olds who ever had sex were using contraception. Compared to older women, young womens pregnancies were ... RESULTS: Among Ghanaian 15-24 year-olds who had ever had sex, one-third (32%) were using contraception. Compared to older women ...
Omisirge (omidubicel) dosing, indications, interactions, adverse effects, and more
Contraception. *See the prescribing information for medications used for conditioning for information on need for effective ... Primary graft failure occurred; immunologic rejection is primary cause of graft failure ... There are insufficient exposure data to provide a recommendation concerning duration of contraception following treatment ... contraception in patients who receive a conditioning regimen. * ...
10th Diczfalusy Meeting - 2016 | Egon and Ann Diczfalusy Foundation
2. Speaker: Metabolic Outcomes in PCOS (Obesity and contraception, 20). 3. Speaker: Obesity and contraception (Atrophic Vagina ... 6. Speaker: Győző Petrányi (Immunologic background of recurrent spontaneous abortion: diagnosis and therapy, 20). Discussion, ... 1. Speaker: David Archer (Microchip Controlled Contraception and Green Contraception, 20). 2. Speaker: Mario Festin (A ... 5. Speaker: Ilpo Huhtaniemi (Male Contraception, 20). Discussion, 20. 13.10 - 14.00. Sponsored Symposium 2.. Lunch Symposium ...
Essentials of Human Diseases and Conditions - Elsevier eBook on VitalSource (Retail Access Card), 7th Edition - 9780323712705
PUBLIC HEALTH PROGRAMS AND PRACTICES
Pharmacotherapy Principles and Practice 5th Edition Chisholm-Burns Test Bank
Trial | NCT00456092
... sexually active FCBP must agree to use TWO adequate forms of contraception while on study medication. A FCBP must agree to have ... immunologic, or other major diseases Any condition, including the presence of laboratory abnormalities, which places the ... must agree to use barrier contraception (latex condoms) when engaging in reproductive sexual activity with FCBP while on study ...
Clinical Trials Register
A highly effective method of contraception is defined as those which result in a low failure rate (i.e. less that 1% per year) ... Suffers from major medical illness such as cardiac, endocrinologic, hepatic, immunologic (other than MS), metabolic, renal, ... If male, he must be willing to use contraception to avoid pregnancies throughout the entire duration of the study and for 90 ... Using a highly effective method of contraception throughout the entire duration of the study and for 6 months (6 menstrual ...
College of Pharmacy News | College of Pharmacy
Coitus Interruptus | Profiles RNS
Hyperemesis Gravidarum Workup: Laboratory Studies, Imaging Studies
A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin
AllergicDisordersPregnancyClinicalDiseaseEffectiveStudiesSearchStudySide effectsWomenOralEarlyAgentsCareIncludeImportantHematologicForms of contraceptionPsychiatricCharacterizationInfertilityReproductiveThreatened abortionHormonalPediatricPregnancyGeneticMeshContraceptiveCyclosporineConcentrationsKidneyModerateEmergencyDosePatientsFormPEOPLEControlHumanMeansCombinationDrugMale
Allergic1
- Known risk factors include allergic rhinitis, nonallergic rhinitis, anatomic obstruction in the ostiomeatal complex, and immunologic disorders. (medscape.com)
Disorders1
- 2008). Immunologic disorders in pregnancy. (healthlinkbc.ca)
Pregnancy2
- Couples are said to be infertile when no pregnancy occurs after a year of having sexual relations without using contraception (the average couple achieve success within this time). (hwalibrary.com)
- Although immunologic factors may influence early embryo implantation, ASRM says routine immunologic testing of couples with infertility is expensive and does not predict pregnancy outcome. (contemporaryobgyn.net)
Clinical2
- To diagnose SLE based on the Systemic Lupus International Collaborating Clinics (SLICC) 2012 criteria, the patient needs to meet four criteria with at least one clinical and at least one immunologic (autoantibodies or low complement) in the absence of biopsy-proven nephritis. (medicalindependent.ie)
- In our case report in this article, the patient had biopsy-proven lupus nephritis along with meeting five-of-11 clinical criteria and four-of-six immunologic criteria of the SLICC criteria. (medicalindependent.ie)
Disease1
- UT Pharmacy and UT Health Science Center San Antonio Assistant Professor Grace C. Lee, Pharm.D., Ph.D. is the first author of a recently published study that unveiled a novel concept, "immunologic resilience," to accurately predict which COVID-19 patients will advance to severe disease and which will not. (utexas.edu)
Effective4
- The project's goal is to increase global access to long-term and effective contraception while minimizing some of its most debilitating side effects. (utexas.edu)
- Using highly effective method of contraception such as implants, injectables, combined oral contraceptives, intrauterine devices (IUDs), intrauterine hormone-releasing system (IUS) at least 1 month prior to screening and willing to continue the control for the duration of the study, and until 3 months after dosing with the study drug. (who.int)
- 5. Male subjects with female partners of child bearing potential must agree to use condoms and use highly effective method of contraception with female partner for the duration of the study and until 3 months after dosing with the study drug and must refrain from donating sperm for this same period. (who.int)
- Participants are females who became pregnant during study SHP647-301, SHP647-302, or SHP647-303, females who are lactating, females who are planning to become pregnant during the study period, or males or females of childbearing potential not agreeing to continue using appropriate contraception methods (i.e. highly effective methods for female and medically appropriate methods for male study participants) through the conclusion of study participation. (ucsd.edu)
Studies2
- Blood hormone tests, chromosome and immunologic studies will be made, as well as scrutiny for infections. (hwalibrary.com)
- Immunologic studies have shown that elevated C-reactive protein (CRP) reflects IL-6-mediated pro-inflammatory pathways, whereas elevated ferritin reveals immune dysregulation in IL-1 and interferon-gamma (IFN-γ). (medscape.com)
Search1
- Results of search for 'su:{Contraception, Immunologic. (who.int)
Study2
- In addition, sexually active FCBP must agree to use TWO adequate forms of contraception while on study medication. (liu.edu)
- 11. All study participants must be willing to be registered into, and comply with, the mandatory pomalidomide (POMALYST®) Risk Evaluation and Mitigation Strategy (REMS®) program and be willing to use contraception 28 days prior to pomalidomide treatment and continue until 120 days after the last dose of pomalidomide. (mountsinai.org)
Side effects1
- Many posters asked questions related to accessing contraception and side effects and sought reassurance from these online forums. (bvsalud.org)
Women1
- It is important for women of child-bearing age to discuss contraception and have planned pregnancies, which often require a multidisciplinary approach. (medicalindependent.ie)
Oral1
- She suffers from untreated chronic hepatitis C virus (HCV) infection and polycystic ovary syndrome (PCOS) and is on oral contraception. (medscape.com)
Early1
- Among the 101 posts on contraception and the COVID-19 pandemic, we explored three main themes: barriers to accessing general healthcare during the early pandemic, problems and concerns specific to contraceptive use, and attempts to navigate the obstacles to contraceptive care or use-related concerns. (bvsalud.org)
Agents1
- The protocol is designed to evaluate two agents, Anti-LAG-3 and Anti-TIGIT, in order to understand their immunologic effects and safety both as single agents and in combination with pomalidomide and dexamethasone. (mountsinai.org)
Care1
- Our results suggest that there were barriers to accessing reliable, high-quality, and evidence-based information about contraception during this disruption in care. (bvsalud.org)
Include1
- Other proposed mechanisms include transport of endometrial tissues via lymphatic ducts and blood vessels, differentiation of progenitor cells from bone marrow into endometrial tissues, and involvement of immunologic processes. (uspharmacist.com)
Important1
- The findings also underscore that conversational and interactive means of seeking out information are important modes for learning about and discussing contraception for some and may be especially helpful during clinic closures and other restrictions on access. (bvsalud.org)
Hematologic1
- The DanceBlue Kentucky Children's Hospital Hematology/Oncology Clinic provides diagnosis of and treatment for childhood hematologic and immunologic disorders and malignancies. (uky.edu)
Forms of contraception2
- Two different nonhormonal forms of contraception are required for women of childbearing potential taking telaprevir. (soxanddawgs.com)
- to standardize institutional practice around prevention and control o high clinical probability of having a child must use two forms of contraception is recommended to start insulin therapy epidemiology and etiology diaper dermatitis, more commonly in the course of a transfusion. (umaine.edu)
Psychiatric1
- For some, honoring that truth may require opting out of a system that leverages fear of the body in service of ever-increasing social and civil control including coerced, mandated, and involuntary treatments - psychiatric, oncologic, immunologic and otherwise. (kellybroganmd.com)
Characterization3
- Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. (nih.gov)
- Characterization of hidden immunologic contact us how to unravel modifications and when oral antibiotics such activities while on libro. (planning411.com)
- After all neoadjuvant study therapy is administered, each subject will undergo cystectomy to evaluate pathologic response to treatment and for immunologic characterization in the resected tissue. (ucsf.edu)
Infertility2
- My research addresses immunologic aspects of human reproductive health, and has contributed to advances in understanding immunological mechanisms underlying male and female infertility, recurrent miscarriage, preeclampsia, gynecologic oncology and the sexual and vertical transmission of HIV-1. (bu.edu)
- While understanding the function of ERK1 and ERK 2 may yield important information for treating infertility in women, this understanding might also lead to ways to prevent ovulation from occurring, for the development of new means of contraception Dr. De Paolo said. (medicalxpress.com)
Reproductive1
- Females and males of reproductive potential: Pregnancy testing and contraception are recommended in adolescents and adults of childbearing potential. (nih.gov)
Threatened abortion1
- 16. [On the diagnostic and prognostic importance of the quantitative immunologic pregnancy test in threatened abortion and in endangered pregnancy]. (nih.gov)
Hormonal1
- Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy while taking tamoxifen. (gymjuice.org)
Pediatric1
- The Contraception Research Branch (CRB) and the Maternal and Pediatric Infectious Disease Branch (MPIDB) both fund extramural research on this topic. (nih.gov)
Pregnancy2
- and the Office of Research on Women's Health (ORWH) of the Office of the NIH Director invite applications for basic studies designed to identify the underlying immunologic and/or genetic mechanism(s) that protect the embryo and fetus from maternal rejection and to elucidate the interactions of the fetal and maternal immune systems in successful pregnancy. (nih.gov)
- Pregnancy testing and contraception are recommended. (nih.gov)
Genetic1
- Despite genetic differences known to elicit strong immunologic responses under other circumstances, i.e. (nih.gov)
Mesh1
- Contraception, Postcoital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
Contraceptive1
- During the course of the study, from study screen until study exit - including the washout period, women of childbearing potential must use a spermicide containing barrier method of contraception in addition to their current contraceptive device. (clinicaltrials.gov)
Cyclosporine2
- subsequent withdrawal of cyclosporine recommended in patients with low to moderate immunologic risk (see General under Dosage and Administration). (drugs.com)
- In patients with low to moderate immunologic risk, withdraw cyclosporine gradually (over a 4- to 8-week period) at 2-4 months posttransplantation and simultaneously increase sirolimus dosage to achieve recommended sirolimus blood concentrations. (drugs.com)
Concentrations1
- 2007. Concentrations and significance of cytokines and other immunologic factors in semen of healthy fertile men. (bu.edu)
Kidney2
Moderate1
- Risk factors include bed rest, burns, hyperco-agulable state, obesity incidence of low serum potassium level is less reliable, because the latter further subdivided into mild, moderate, or severe hypoxemia is not able to use contraception requiring insertion into the esophagus for more than ms specifically identifies patients at risk for pseudomonas aeruginosa is inherently resistant to penicillin and cephalosporins, presumptive therapy for uncomplicated episodes of syncope, palpitations, or exercise intolerance. (aaan.org)
Emergency2
- Where has Emergency Contraception Available? (xclenz.com)
- How shortly is Emergency Contraception Cost? (xclenz.com)
Dose1
- Complications cardiac defects prior to dental enamel results from ingestion to begin their contraception on the dose of drug from other causes. (albionfoundation.org)
Patients1
- This risk calculator or prediction o outcome in patients unresponsive to this topic remains controversial, regardless of whether to anticoagulate is o en times the risk of neurodevelopmental abnormalities. (umaine.edu)
Form2
- Women of childbearing potential must practice abstinence or be using an acceptable form of contraception throughout the duration of the study. (clinicaltrials.gov)
- He is sexually active and does not use any form of contraception or protection. (myacademic-support.com)
PEOPLE2
- This graph shows the total number of publications written about "Contraception, Postcoital" by people in this website by year, and whether "Contraception, Postcoital" was a major or minor topic of these publications. (ouhsc.edu)
- Below are the most recent publications written about "Contraception, Postcoital" by people in Profiles. (ouhsc.edu)
Control1
- The operative mechanisms that permit the embryo and/or fetus to develop without being rejected, if identified, could provide insights into the induction, maintenance, and control of immunologic tolerance. (nih.gov)
Human1
- 1. Quantitative immunologic assay of human chorionic gonadotropin in normal and abnormal pregnancies. (nih.gov)
Means1
- Pregnant or nursing women or women of child bearing potential not using at least 1 medically accepted means of contraception from the time of enrollment in the study until 1 month after completion of the second phase. (nih.gov)
Combination1
- A synthetic progestin commonly used alone or in combination with an estrogen for contraception. (medindex.am)
Drug1
- Contraception must not responded to make testosterone, and put this drug. (planning411.com)