evolving all we are: 十月 2013

Our People | Land Conservation Assistance Network

Ultraconserved Elements in the Human Genome - NASA/ADS

Distribution of gene conservation across the Parcubacte | Open-i

Genomic Data Analysis Using DNA Structure: An Analysis of Conserved Nongenic Sequences and Ultraconserved Elements

Interpreting Structure Conservation Analysis

Concentrating on conservation in 2015: Organizations encourage residents to get involved - News - The Independent - Massillon,...

Converting endangered species categories to probabilities of extinction for phylogenetic conservation prioritization

AllPage.PageTitle; : Wildlife conservation in a changing climate

Conservation Lands & Trails | Weston, MA

Department of Ecology and Evolutionary Biology | indivfaculty

April « 2013 « The League of Reason Blog

VENN, a tool for titrating sequence conservation onto protein structur by Jay Vyas, Michael R. Gryk et al.

140 Water conservation ideas | water conservation, conservation, conservation activities

Evaluating conservation spending for species return: A retrospective analysis in California, Conservation Letters | 10.1111/j...

Functional Sequences For Imaging Cancer In The Prostate | 3303

Association for Rivers and Coastal-Ecosystems Conservation Volunteer Opportunities - VolunteerMatch

Quantitative Conservation of Vertebrates | Download ebooks online

The Institute for Regional Conservation

The Institute for Regional Conservation

Parity conservation and bootstraps - CaltechAUTHORS

14 Days Environment Conservation Volunteering Project Uganda - Idealist

Middlesex County College conservation

Volunteering<...

Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia<...

G-protein coupled receptors (GPCRs) belong to biologically important and functionally diverse | Application of Computational...

Gene - wikidoc

polychromy - Conservation & Collections Care blog

Family turtle conservation holidays

Notch Signaling | www.antibodies-online.com

M.S. Conservation Leadership

Pathway expression conservation and divergence. (a) Top | Open-i

Kaiserstuhl Conservation Park

Conservation & Green News | The Nature Conservancy

Upcoming Events | SHAKE in Conservation

South Central College conservation

Campaigns for protection and conservation · Causes

Architectural design, development, research and conservation on Sint Maarten - DAM Caribbean

Dasuquin® is Something to Howl About!

A Phylogeny of Birds Based on Over 1,500 Loci Collected by Target Enrichment and High-Throughput Sequencing

eCite - The zinc transporter SLC39A7 (ZIP7) harbours a highly-conserved histidinerich N-terminal region that potentially...

Conservation Awards & Grants

Webcam: Ambassador Wolves Zephyr, Alawa, and Nikai | Wolf Conservation Center

Biodiversity and Conservation | Prospects.ac.uk

AcylCoA Binding Protein (thing) by BioTech - Everything2.com

Ocean Conservation Projects - The Ocean Foundation

Anthony Ochieng Archives - Conservation Careers

Conservation of Energy

Math.Content.4.MD.A.1 Standards | Common Core Lesson Plans | Share My Lesson

ELA-Literacy.W.8.3.a Standards | Common Core Lesson Plans | Share My Lesson

PCDHB13 - ويكيبيديا

Elephant Conservation Center Review - Eternal Expat

Human-Nature Escapes CIC | Nature Conservation go green

Ecology and Society: Efficient Conservation in a Utility-Maximization Framework

California Nature Conservation, Environment Issues | The Nature Conservancy

Map turtle status and conservation by Greg George - CTTC

A look back at some of the biggest bird conservation stories of 2019 | BirdLife

Wildlife Ecology and Conservation

Butterleaf State Conservation Area

Geocaching - Toronto and Region Conservation Authority (TRCA)

The Savannah Process

Conserved sequence

Conserved non-coding sequence

NAPP (database)

MMP3

Conserved signature indels

RVxP motif

EF-4

Piscine orthoreovirus

STIM2

C1orf94

Blueberry mosaic associated ophiovirus

SRNA-Xcc1

Respiratory syncytial virus

XMAP215-Dis1 family

Sequence homology

NTP binding site

Aminoacyl tRNA synthetase

FluChip

MADS-box

Mathieu Blanchette (computational biologist)

C1orf68

C1orf122

Bacterial transcription

GvpA

Ultra-conserved element

HCONDELs

Histone H2B

ATG3

Cytokine-like protein 1

FNDC5

Phyllanthaceae

Uridine monophosphate synthase

NFIX

HOXD8

Nonviolent video game

Coronavirus nucleocapsid protein

Sequence motif

Dietrich von Schlechtendal

DDX46

Prokaryotic DNA replication

Ribeira Grande City Hall

TENM3

Beulah Garner

Cordon-bleu protein-like 1

WIPI2

Genomic imprinting

Endless Forms Most Beautiful (book)

PIR (gene)

NXPH1

TIMM10

Cooma Cottage

Very long-chain acyl-CoA synthetase

Interferon

Sulfolobus

MiR-137

PhotoRC RNA motifs

PARC (gene)

FLVCR2

Prunus × nudiflora

Voltage-gated ion channel

Genomes11

• The mechanisms are so similar, in fact, that a genetic element called an enhancer from the sea sponge Amphimedon queenslandica can drive transcription in specific cell types in mice and zebrafish, despite the fact that the genomes of these animals don't normally include a similar sequence, according to a study published late last year in Science . (the-scientist.com)
• Mammalian genomes contain highly conserved sequences that are not functionally transcribed. (unige.ch)
• In silico identification of conserved intercoding sequences in Leishmania genomes: unraveling putative cis-regulatory elements. (fiocruz.br)
• To identify the elements involved in the control of gene expression, we conducted an in silico investigation to find conserved intercoding sequences (CICS) in the genomes of L. major, L. infantum, and L. braziliensis. (fiocruz.br)
• The sequencing of the genomes from extinct hominins has revealed that changes in some brain-related genes have been selected after the split between anatomically-modern humans and Neanderthals/Denisovans. (frontiersin.org)
• 2017 ). A high percentage of prokaryotic genomes (83%) contain two or more copies of 16S rRNA genes, and the sequences are nearly identical among the copies of 16S rRNA genes (Sun et al. (springer.com)
• 2013 ). In particular, halophilic archaea of the genus Haloarcula have long been known to harbour significantly different sequences of 16S rRNA genes in their genomes (Mevarech et al. (springer.com)
• Although, providing the massive amount of data by recent genome sequencing projects but many of these genomes are still not fully annotated as well as consist of genes/proteins with unknown function and structure. (avensonline.org)
• When analyzing the polyketide gene clusters from the sequenced dermatophyte genomes 1 , 8 , we found an orthologous gene cluster, which is also conserved in pathogenic fungi Aspergillus fumigatus and Neosartorya fischeri 10 , 11 ( Figure 1 ). (cdc.gov)
• In addition to these four well-conserved "core PKS genes", the neighboring regions encode additional genes, some of which are highly syntenic and conserved between genomes ( Figure 1 ). (cdc.gov)
• Cardiocondyla obscurior has the smallest of the sequenced ant genomes and its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution. (wurmlab.com)

Genes16

• Molecular characterization of the virus was done by using polymerase chain reaction amplification, cloning, and DNA sequencing of conserved orthopoxvirus genes such as the vaccinia growth factor (VGF), thymidine kinase (TK), and hemagglutinin. (cdc.gov)
• Gene sequences showed 99% homology with vaccinia virus genes and were clustered together with the isolated virus in the phylogenetic tree. (cdc.gov)
• The arrangement of these genes and the major noncoding region is relatively conserved through evolution although gene rearrangements have been described for diverse lineages. (biomedcentral.com)
• In addition, most vertebrate mitogenomes conserve a characteristic stem-and-loop structure between tRNA Asn and tRNA Cys genes that acts as the putative origin of light-strand replication (O L ) [ 5 ]. (biomedcentral.com)
• The organization of the 37 genes and the major noncoding region varies considerably between metazoan classes but is relatively conserved within Vertebrata [ 2 ]. (biomedcentral.com)
• The de novo appearance of genes from random non-coding sequence has also never been observed. (creation.com)
• The same, or very similar, sequences of mutations would have had to occur in different DNA sequences in two different branches of the evolutionary tree to produce two genes that are very homologous to one another. (creation.com)
• Prokaryotes harbour 16S rRNA genes encoding rRNA in the small subunit of the prokaryotic ribosome, and the sequences are highly conserved. (springer.com)
• 2017 ). The different sequences of 16S rRNA genes were first reported in Haloarcula marismortui (Mevarech et al. (springer.com)
• Current diagnostic PCR assays target a variety of SARS CoV-2 genes and the vast majority target sequences in regions of the SARS CoV-2 genome that are highly conserved. (who.int)
• EST dataset, RNA sequences, or conserved genes can be used to evaluate the completeness of genome assembly. (cd-genomics.com)
• 90% identity between them) ( Table S3, Supplementary Information ), and the lower sequence homology to those in A. fumigatus and N. fischeri (~70% identity, Table S3 ), raise an interesting question as to whether these fungi produce similar compounds, and whether the presence of additional conserved genes may lead to further tailoring of the neosartoricin scaffold. (cdc.gov)
• To examine the activities of the conserved core PKS genes from dermatophytes, we cloned the clusters using yeast recombination 12 followed by expression in Aspergillus nidulans ( Figure S1, Supplementary Information ). (cdc.gov)
• These transcriptomic data of A. davidianus should open the door to molecular evolution studies based on the entire transcriptome or targeted genes of interest to sequence. (rna-seqblog.com)
• The expressed sequence tags (ESTs), hormones and genes responsible for regulating wood formation were identified in Populu s increasingly [7, 8, 9]. (researchsquare.com)
• In addition, IGS sequencing (e.g., sequencing of intergenic regions between the 16S and 23S rRNA genes) has been used to taxonomy studies, while partial sequencing of the gene gtfB , which encodes the enzyme glucosyltransferase B, has been used to investigate enzymatic activity and virulence 11-12 . (bvsalud.org)

Genomic4

• It is likely that genomic variation in conserved non-genic sequences is associated with phenotypic variability and human disorders. (unige.ch)
• He thanked CDC and KTL for their support in providing accurate genomic sequencing results of polioviruses in a timely manner, as this greatly facilitated planning and targeting the polio eradication activities. (who.int)
• The software tools CHAOS and DIALIGN are used to align a pair of syntenic genomic sequences, e.g. from human and mouse. (uni-bielefeld.de)
• The Human Genome Variation Society (HGVS) has established a sequence variant nomenclature , an international standard used to report variation in genomic, transcript and protein sequences. (ucsc.edu)

Next-Generation Sequencing4

• The evolution of Next-Generation Sequencing (NGS) has considerably reduced the cost per sequenced-base, allowing a significant rise of sequencing projects, mainly in prokaryotes. (biomedcentral.com)
• followed by next-generation sequencing and virus isolation. (cdc.gov)
• The study of microbial communities from environment- and human-derived samples through Next Generation Sequencing (NGS) methods has revealed a vast complexity in those ecological niches where hundreds or thousands of microbial species co-inhabit and functionally interact. (biomedcentral.com)
• Further study with advanced tools such as next-generation sequencing is required to elucidate the nature of the observed variation within clones. (iita.org)

Proteins7

• The rules underlying how enhancer sequences interact with these proteins to modulate transcription remain murky, and scientists are still sorting out the details of enhancer biology and trying to understand how function is conserved even as the DNA code mutates. (the-scientist.com)
• To identify amino acid residues responsible for the tRNA recognition, we have carried out the alanine substitution mutagenesis of the basic amino acid residues that are conserved only in TrmH enzymes and not in the other SpoU proteins. (nih.gov)
• However, when coupled with alternative splicing, there appears to be an exponential increase in the diversity of proteins encoded, which display novel functions and are conserved by natural selection. (cell.com)
• These proteins contain a hydrophobic signal sequence at their N-terminus which tells the signal recognition particle (SRP) complex to translocate them into the ER. (creation.com)
• The members of this family have been characterized according to their sequence or structure, including a large number of proteins. (scirp.org)
• Although they have 20 to 70% amino acid sequence identity, these proteins share a conserved tertiary structure comprised of ten beta sheets and two alpha helixes. (nottingham.ac.uk)
• ps_scan will be run with your sequence against profiles specific for Proteins described elsewhere . (inra.fr)

Including the highly-conserved1

• bp construct of the upstream region, including the highly-conserved regions Reg I and Reg II, increased expression 100-fold, and successive 5' deletions reduced expression relative to the full 4.5. (mssm.edu)

20172

• 2017) Sequencing and de novo transcriptome assembly of the Chinese giant salamander (Andrias davidianus) . (rna-seqblog.com)
• When a new sub-group of Asian A(H7N9) viruses emerged in China in 2017, Chinese public health officials posted the genetic sequence of the virus and CDC was able to make a virus based on that genetic sequence. (cdc.gov)

Highly23

• The high degree of synteny among Leishmania species is accompanied by highly conserved coding sequences (CDS) and poorly conserved intercoding untranslated sequences. (fiocruz.br)
• IMSEAR at SEARO: Highly conserved D-loop-like nuclear mitochondrial sequences (Numts) in tiger (Panthera tigris). (who.int)
• Zhang W, Zhang Z, Shen F, Hou R, Lv X, Yue B. Highly conserved D-loop-like nuclear mitochondrial sequences (Numts) in tiger (Panthera tigris). (who.int)
• We observed that many aptamers have a conserved hairpin, yet the sequence of the hairpin can be highly variable. (bvsalud.org)
• We previously identified two highly conserved regions upstream of the long-wave sensitive opsin (LWS) gene cluster in teleosts. (mssm.edu)
• In order to further investigate how elements in this region control opsin gene expression, we tested constructs encompassing the highly conserved regions and the less conserved portions upstream of the coding sequences in a promoter-less luciferase expression system. (mssm.edu)
• Two Factors that Bind to Highly Conserved Sequences in Mammalian Type " by Nancy R. Manley, Mary M. O'Connell et al. (dartmouth.edu)
• Two Factors that Bind to Highly Conserved Sequences in Mammalian Type C Retroviral Enhancers. (dartmouth.edu)
• We used electrophoretic mobility shift and methylation interference assays to study nuclear factors which bind to a region of these enhancers whose sequence is identical between Moloney and Friend viruses and particularly highly conserved among 35 mammalian type C retroviruses whose enhancer sequences have been aligned (E. Golemis, N. A. Speck, and N. Hopkins, J. Virol. (dartmouth.edu)
• Manley NR, O'Connell M, Sun W, Speck NA, Hopkins N. Two factors that bind to highly conserved sequences in mammalian type C retroviral enhancers. (dartmouth.edu)
• They share highly conserved linear sequence regions or similar 3D structures, and are therefore considered as panallergens. (medscape.com)
• MicroRNAs are small, highly conserved, non-coding RNAs that regulate gene expression of target mRNAs through cleavage or translational inhibition. (usda.gov)
• The FOXP2 protein sequence is highly conserved. (bionity.com)
• Furthermore, some usually highly conserved residues are not conserved (for a comparison of atypical homeodomains see Ref. 4). (wormbase.org)
• Mycobacterium genus-specific primers derived from highly conserved sequences in the ITS region and the flanking 16S rRNA gene were used. (cdc.gov)
• with have amino acid sequences that are highly conserved in mammalian species. (kenyon.edu)
• Highly conserved regions are less likely to mutate, therefore there is a high likelihood that the diagnostic test will remain accurate in the presence of variants. (who.int)
• The Us9 gene is highly conserved among the alphaherpesviruses sequenced to date, yet its function remains unknown. (vetres.org)
• Viral mutants lacking the highly conserved Us9 acidic motif required for endocytosis and trans -Golgi network targeting are defective for directional spread in the rat visual system. (vetres.org)
• CYP20A1s share a highly conserved N-terminal region and unusual sequences in the I-helix and the heme-binding CYP signature motifs. (oregonstate.edu)
• A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. (ensembl.org)
• We conclude that sequence analysis of the two repetitive loci introduced here may be highly useful for routine typing of C. difficile . (biomedcentral.com)
• In particular, LRRearch uses matrix library derived from 11 residue stretch LRR-Highly Conserved Segments and therefore provides the possibility to search for a great variety of different LRR sites. (lrrsearch.com)

Residues that are conserved1

• In order to make the profiles more specific, residues that are conserved in the whole family are lightened and residues specific to each subfamily are emphasized. (inra.fr)

Untranslated Regions1

• 2006) RNA "A conserved sequence motif in 3' untranslated regions of ribosomal protein mRNAs in nematodes. (wormbase.org)

Viral4

• Patient A had no identified risk factor for HIV infection and was infected with a strain of HIV closely related to that of her dentist as determined by viral DNA sequencing. (cdc.gov)
• In contrast to 2002/2003, during the outbreak of the SARS-CoV virus, we now have a new tool with single cell RNA-Sequencing that allows us to understand the heterogeneity of viral infections at an unprecedented level. (dolomite-bio.com)
• It includes many viruses that probably do not meet the notability criteria of Wikipedia (ex Myotis ricketti alphacoronavirus Sax-2011, Myotis ricketti alphacoronavirus Sax-2011 etc, which are merely viral sequences detected in samples from some large-scale survey studies), but miss many that do qualify an article (However, I guess the inclusion criteria is up to en-wikipedians to decide. (wikizero.com)
• Purified DNA will be analyzed for 37 types of HPV by means of a multiplex polymerase-chain-reaction (PCR) assay targeted to the conserved L1 region of the viral genome, using PGYM09/11 primer pools and primers for ß-globin (33). (cdc.gov)

Mammalian1

• Here we describe the further characterization of this binding activity, termed MCREF-1 (for mammalian type C retrovirus enhancer factor 1), and the identification of a consensus sequence for its binding, GGN8GG. (dartmouth.edu)

Variation4

• Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy. (uchicago.edu)
• Donfack J, Schneider DH, Tan Z, Kurz T, Dubchak I, Frazer KA, Ober C. Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy. (uchicago.edu)
• Although, the polymorphisms are generally thought to be a variation in the gene sequence, histopathologicai studies suggest that the aggressiveness of tumour progress, histological type and survival rate may be related to the host variation. (bl.uk)
• We describe two tandem repeat loci, designated 'TR6' and 'TR10', which display extensive sequence variation that may be useful for sequence-based strain typing. (biomedcentral.com)

Variants6

• In particular, the NS5B region contained long stem-loop structures of up to 38 internally paired nucleotides which were evolutionarily conserved between human and chimpanzee HGV/GBV-C variants. (ox.ac.uk)
• Screening for sequence variants in the glucokinase gene was performed by denaturing gradient gel electrophoresis and direct sequencing in 132 children with maturity onset diabetes of the young (MODY) and in 9 children with chronic fasting hyperglycaemia but without laboratory evidence for Type I (insulin-dependent) diabetes mellitus and with normoglycaemic parents ("non-classical" MODY). (nih.gov)
• See 10 reference mRNA sequence splice variants for the RHD gene. (nih.gov)
• What's more, whole genome re-sequencing is an indispensable part of genome-wide association study (GWAS), where common genetic variants in different individuals are assessed to determine if a variant is associated with a particular phenotype. (cd-genomics.com)
• Belted mice have sequence variants in the Adamts20 gene encoding a secreted metalloprotease [ 16 ], which was shown to be required for melanoblast survival [ 17 ]. (plos.org)
• To determine the likely pathogenic gene variants in the family pedigree, we performed whole-exome sequencing in this study. (biomedcentral.com)

Motif4

• Computer -aided prediction of aptamer sequences has been focused on primary sequence alignment and motif comparison. (bvsalud.org)
• Analysis of the region around the polyadenylation signal in many ribosomal protein mRNAs indicates the conservation of a sequence motif UUGUU occurring both before and immediately after the polyadenylation signal. (wormbase.org)
• The Drosophila gene prospero (pros) encodes a sequence motif with similarity to homeodomains. (wormbase.org)
• The structure of BRCA1 is not strikingly homologous to other known molecules apart from the presence of a ring zinc finger domain and a 10 amino acid granin motif which are thought to be significant due to fact that they both are conserved in humans and other species studied. (bl.uk)

Species15

• By using cross-species comparative sequence analyses, we have identified conserved noncoding sequences (CNSs) upstream of the Ifng gene, one of which, located -22 kb from the transcriptional start site, contains clustered consensus binding sequences of transcription factors that function in T cell differentiation. (wustl.edu)
• We developed a sensitive sequence alignment pipeline to identify conserved noncoding sequences (CNSs) in the Andropogoneae tribe (multiple crop species descended from a common ancestor ∼18 million years ago). (zhangtaolab.org)
• The rainbow trout genome sequence is not available yet, which does not allow microRNAs prediction for this important aquaculture and biomedical research species. (usda.gov)
• But then we looked at the gene sequence, and it was conserved across species. (innovations-report.com)
• Evolution cannot explain why this isoform is conserved throughout the alleged evolutionary tree, yet two structurally significantly different isoforms occur in one species. (creation.com)
• Sequencing of the approximately 250-bp-long ITS amplicons of the three MCC member species showed differences in 24 to 34 bases, thereby yielding variable deduced restriction maps. (cdc.gov)
• ITS PCR-restriction analysis using the in silico-selected restriction enzyme MaeII or HphI differentiated the three MCC members from one another and from other RGM and SGM species without sequencing. (cdc.gov)
• A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. (bvsalud.org)
• De novo sequencing generates the first genome map for a species, thus providing a valuable reference sequence for re-sequencing. (cd-genomics.com)
• Oxford Nanopore and PacBio sequencing systems enable a faster and more accurate characterization of any species at the nucleotide level. (cd-genomics.com)
• Whole genome resequencing can identify DNA biomarkers such as single nucleotide polymorphism (SNPs), insertions and deletions (indels), structure variations (SVs), copy number variations (CNVs) and other genetic changes of the sequenced species with high accuracy. (cd-genomics.com)
• CD Genomics combines both Illumina HiSeq and PacBio systems to provide a fast and accurate whole genome sequencing and bioinformatics analysis for any species. (cd-genomics.com)
• Repetitive sequences are abundant in a wide range of species, from microbes to mammals. (cd-genomics.com)
• AGenDA is a gene-prediction tool that is based on cross-species sequence comparison. (uni-bielefeld.de)
• By sequencing the 16S-23S intergenic region, it was found that all of the isolates belonged to the species S. mutans . (bvsalud.org)

FASTA2

• The data may be either a list of database accession numbers, NCBI gi numbers, or sequences in FASTA format. (nih.gov)
• The Input data for PeroxiScan are Protein sequences in fasta format. (inra.fr)

Putative cis-regulatory1

• More than half of putative cis-regulatory sequences (identified via other methods) overlapped with CNSs detected in this study. (zhangtaolab.org)

Transcript3

• Illuminating enhancer transcription at nucleotide resolution with native elongating transcript sequencing (NET-Seq). (mpg.de)
• Genome-wide profiling of RNA polymerase transcription at nucleotide resolution in human cells with native elongating transcript sequencing. (mpg.de)
• Native elongating transcript sequencing reveals human transcriptional activity at nucleotide resolution. (mpg.de)

Protein sequences2

• The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. (nih.gov)
• LRRsearch is a service-based application for prediction of leucine-rich repeats (LRRs) in protein sequences. (lrrsearch.com)

Nucleotide2

• We used VGF-homologous and TK gene nucleotide sequences to construct a phylogenetic tree for comparison with other poxviruses. (cdc.gov)
• Whole genome sequencing data and RNA-seq data from this study have been submitted to the European Nucleotide Archive under accessions PRJEB14604 and PRJEB14606. (plos.org)

Upstream2

• In this study we have carried out a detailed comparison of the structure of the 3'untranslated region (3'UTR) of HGV/GBV-C with that of the upstream NS5B coding sequence. (ox.ac.uk)
• The belt-associated variant was a copy number variant (CNV) involving the quadruplication of a 6 kb non-coding sequence located approximately 16 kb upstream of the TWIST2 gene. (plos.org)

Evolutionary3

• The results serve as an extreme example of what scientists are now recognizing as trends among enhancers-that activity can be conserved over long evolutionary timescales and that such conserved activity doesn't require DNA sequences to match perfectly. (the-scientist.com)
• Sequence similarity was brought in through Protein Data Bank and non-redundant database using BLASTp program of NCBI and a search for templates revealed that yjaB shares 97% homology to a protein of Escherichia coli, indicating this protein is evolutionary conserved and was found with acetyltransfarase. (avensonline.org)
• Moreover, tandem repeat sequences enabled the reconstruction of the isolates' largely clonal population structure and evolutionary history. (biomedcentral.com)

Bioinformatics2

• In this study, soybean miRNAs associated with stress responses (drought, salinity, and alkalinity) have been identified and analyzed in combination with deep sequencing technology and in-depth bioinformatics analysis. (biomedcentral.com)
• In recent years, it has been possible to identify miRNAs through either bioinformatics or sequencing. (biomedcentral.com)

Illumina2

• Genome sequencing on the Illumina platform was performed as previously described [ 8 ]. (jgenomics.com)
• We combine both Illumina (short reads) and PacBio (long reads) platforms to achieve whole genome de novo assemblies and re-sequencing for viruses, microbes , plants, animals and humans . (cd-genomics.com)

Whole genome5

• CD Genomics has been providing the accurate and affordable whole genome sequencing service for couple of years. (cd-genomics.com)
• Whole genome sequencing represents the determination of the complete DNA sequence of an organism's genome at a single time, which entails chromosomal DNA as well as DNA contained in mitochondria and chloroplasts. (cd-genomics.com)
• Whole genome sequencing provides a powerful tool for both de novo sequencing and re-sequencing. (cd-genomics.com)
• The general workflow for whole genome sequencing is outlined below. (cd-genomics.com)
• Whole genome sequence data of 2 belted and 130 control cattle yielded only one private genetic variant in the critical interval in the two belted animals. (plos.org)

Primary sequences2

• Machine Learning Directed Aptamer Search from Conserved Primary Sequences and Secondary Structures. (bvsalud.org)
• Taking such secondary structure information into consideration, a new algorithm combining conserved primary sequences and secondary structures is developed, which combines three scores based on sequence abundance, stability, and structure, respectively. (bvsalud.org)

Enhancer sequences1

• In an alternative "billboard" model, TF binding to enhancer sequences doesn't rely on grammar: the order, number, and spacing can vary and still influence gene expression, sometimes in different ways. (the-scientist.com)

Isolates6

• Here, we report and compare the complete genome sequence of four recent isolates of L . borgpetersenii serovar Hardjo designated strain TC112, TC147, TC129, and TC273. (jgenomics.com)
• Four isolates (designated strains TC112, TC129, TC147, and TC273) cultured from bovine urine during that study have now been fully sequenced and are compared herein. (jgenomics.com)
• Based on an investigation of 154 C. difficile isolates comprising 75 ribotypes, tandem repeat sequencing demonstrated excellent concordance with widely used PCR ribotyping and equal discriminatory power. (biomedcentral.com)
• Isolates from this patient, sequenced by the state laboratory, demonstrated genotypic changes in F13L associated with tecovirimat resistance. (cdc.gov)
• Next, the isolates were differentiated by sequencing a specific region of the gene encoding the enzyme glucosyltransferase B ( gtfB ). (bvsalud.org)
• Based on the genetic similarity of the isolates and pattern of amino acid variations identified by partial sequencing of the gtfB gene, base-pair changes were identified and correlated with different virulence patterns among the isolates. (bvsalud.org)

Structures1

• Evolutionarily conserved RNA secondary structures in coding and non-coding sequences at the 3' end of the hepatitis G virus/GB-virus C genome. (ox.ac.uk)

Eukaryotes1

• Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. (nih.gov)

Similarity1

• Find regions of similarity between this sequence and other sequences using BLAST. (nih.gov)

Humans2

• While there are some examples of "ultraconserved" enhancer elements that are identical in rodents and humans, increased genome sequencing has revealed that enhancers often evolve rapidly, accumulating substantial sequence changes over relatively short periods. (the-scientist.com)
• The Ruvkun lab identified a second microRNA, let-7 , which also regulates translation of its target gene via imperfect base pairing to the 3' untranslated region of that mRNA, and showed that the sequence and regulation of the let-7 microRNA is conserved across animal phylogeny including humans. (thevalleefoundation.org)

Genome assembly2

• We combine the data from HiSeq, PacBio, and Sanger sequencing to ensure the accuracy of genome assembly in hyper repetitive and heterozygous regions. (cd-genomics.com)
• Genome survey provides an initial view of a genome, and develop strategies for deep sequencing and genome assembly. (cd-genomics.com)

Amino acids1

• Sequences longer than 2'000 amino acids will be truncated. (inra.fr)

Genetic4

• In vitro germplasm conservation is a very useful tool in yam improvement strategies but very little is known about the genetic integrity and stability of in-vitro conserved yam plants. (iita.org)
• More than 6,000 flu viruses undergo full genetic sequencing as a first step after they arrive at CDC. (cdc.gov)
• Genetic sequencing can give us information about each virus based on decades of other laboratory work. (cdc.gov)
• If we have the genetic sequence information, we can actually build the same virus in our labs and use it to make a CVV. (cdc.gov)

Secondary structure1

• Has a conserved secondary structure or a structured region. (rnacentral.org)

CDNA2

• 4, 5 Complex cDNA probes can cross-hybridize to related sequences, and low-intensity hybridization indicators are challenging to interpret. (irjs.info)
• Zebrafish CYP20A1 cDNA was cloned, sequenced, and aligned with cloned human CYP20A1 and predicted vertebrate orthologs. (oregonstate.edu)

RRNA gene3

• To verify the hypothesis, we performed sequence analyses and expression surveys of each 16S rRNA gene in eight Haloarcula strains. (springer.com)
• The 5S rRNA gene sequences are almost identical among the rRNA operons. (springer.com)
• For 16S rRNA gene sequences, rrsB and rrsC ( rrsBC ) show almost identical sequences, whereas rrsA shows different sequences (4-6%) from rrsBC (Mevarech et al. (springer.com)

Phylogenetic4

• Thus, such sequences represent molecular 'fossils' that can shed light on evolution of the mitochondrial genome and may be the most appropriate outgroup for phylogenetic analysis. (who.int)
• This is also proved by comparing the phylogenetic trees reconstructed using the D-loop sequence of snow leopard and the 287-bp Numts as outgroup. (who.int)
• The amino acid sequences of several lipocalins from different domestic animals (mouse, dog, cat, bull, hamster, horse and pig) were used to determine the degree of kinship by phylogenetic studies. (scirp.org)
• Tandem repeat sequence typing resolves phylogenetic diversity to a level equivalent to PCR ribotypes. (biomedcentral.com)

Region5

• Links in the FEATURES table will also highlight the corresponding region of the sequence. (nih.gov)
• Finds sub-sequence or patterns in the sequence and highlights the matching region. (nih.gov)
• DNA sequence analysis of the conserved region around the SOD1 gene locus in recessively inherited ALS. (cdc.gov)
• Profiles are built on the whole conserved region of each subfamily. (inra.fr)
• Methods: S. mutans samples were isolated from the saliva of 30 children with varying histories of dental caries, and they were characterized according to morphological and biochemical markers and the sequences of their 16S-23S intergenic spacer region. (bvsalud.org)

Regulatory2

• Clone REA516 recognizes the human and mouse interferon regulatory factor 8 (IRF-8) antigen, a 50 kDa transcription factor, which is also known as interferon consensus sequence-binding protein (ICSBP). (miltenyibiotec.com)
• IRF-8 belongs to the family of interferon regulatory transcription factors, which consists of nine members in both human and mice and is characterized by a conserved N-terminal DNA-binding domain with a unique tryptophan pentad repeat. (miltenyibiotec.com)

Different sequences1

• They are thought to arise via convergent evolution, although it is difficult to understand how completely different sequences can give shape to the same structure. (creation.com)

20201

• 2020. A conserved sequence signature is essential for robust plant miRNA biogenesis. . (ncbs.res.in)

Nucleotides1

• This rRNA sequence is 116 nucleotides long and is found in [Eubacterium] siraeum V10Sc8a. (rnacentral.org)

Alignment2

• Multiple sequence alignment (MSA) was used to locate the conserved residues. (avensonline.org)
• Repeats have always presented technical challenges for sequence alignment and assembly. (cd-genomics.com)

Analyses1

• Sequence analyses indicated that the sequence of 287 bp was a D-loop-like nuclear mitochondrial sequence (Numts), indicating a nuclear transfer that occurred approximately 4.8-17 million years ago in the tiger and 4.6-16 million years ago in the leopard. (who.int)

Prediction1

• MicroRNAs are most often identified through computational prediction from genome sequences. (usda.gov)