Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.
A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.
A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.
A group of cells that includes FIBROBLASTS, cartilage cells, ADIPOCYTES, smooth muscle cells, and bone cells.
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue.
Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)
Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.
A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
A CCN protein family member found at high levels in NEPHROBLASTOMA cells. It is found both intracellularly and in the EXTRACELLULAR MATRIX and may play a role in the regulation of CELL PROLIFERATION and EXTRACELLULAR MATRIX synthesis.
A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.
Exposure of the root surface when the edge of the gum (GINGIVA) moves apically away from the crown of the tooth. This is common with advancing age, vigorous tooth brushing, diseases, or tissue loss of the gingiva, the PERIODONTAL LIGAMENT and the supporting bone (ALVEOLAR PROCESS).
Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.
Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state.
Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.
Surgical reshaping of the gingivae and papillae for correction of deformities (particularly enlargements) and to provide the gingivae with a normal and functional form, the incision creating an external bevel. (Dorland, 28th ed)
Oral tissue surrounding and attached to TEETH.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Bony cavity that holds the eyeball and its associated tissues and appendages.
Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).
Signal molecules that are involved in the control of cell growth and differentiation.
An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.
Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Classical loci in ACUPUNCTURE. They are main and collateral channels, regarded as a network of passages, through which vital energy (Qi) circulates and along which acupoints (ACUPUNCTURE POINTS) are distributed. The meridians are a series of 14 lines upon which more than 400 acupoints are located on the body. (The Pinyin Chinese-English Dictionary, p. 359; Dr. Wu Lancheng, Academy of Traditional Chinese Medicine, Beijing)
A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
A fibrillar collagen consisting of three identical alpha1(III) chains that is widely distributed in many tissues containing COLLAGEN TYPE I. It is particularly abundant in BLOOD VESSELS and may play a role in tissues with elastic characteristics.
A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It may play an important role in the development of branched CAPILLARIES during EMBRYOGENESIS.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A wedge-shaped collar of epithelial cells which form the attachment of the gingiva to the tooth surface at the base of the gingival crevice.
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
A family of structurally related collagens that form the characteristic collagen fibril bundles seen in CONNECTIVE TISSUE.
Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris.
A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.
A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.
Restoration of integrity to traumatized tissue.
A genus of large SEA CUCUMBERS in the family Holothuriidae possessing thick body walls, a warty body surface, and microscopic ossicles.
Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.
Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
Glycoproteins which have a very high polysaccharide content.
Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
Components of the extracellular matrix consisting primarily of fibrillin. They are essential for the integrity of elastic fibers.
A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.
A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
Layers of connective tissue of variable thickness. The superficial fascia is found immediately below the skin; the deep fascia invests MUSCLES, nerves, and other organs.
Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.
A collective term for diseases of the skin and its appendages and of connective tissue.
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.
A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
A genus of very large, epibenthic SEA CUCUMBERS in the family Stichopodidae, commercially harvested in Southeast Asia for food.
Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
Elements of limited time intervals, contributing to particular results or situations.
Monomeric subunits of primarily globular ACTIN and found in the cytoplasmic matrix of almost all cells. They are often associated with microtubules and may play a role in cytoskeletal function and/or mediate movement of the cell or the organelles within the cell.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Any of certain small mammals of the order Hyracoidea.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
The protein components that constitute the common core of small nuclear ribonucleoprotein particles. These proteins are commonly referred as Sm nuclear antigens due to their antigenic nature.
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
A biosynthetic precursor of collagen containing additional amino acid sequences at the amino-terminal and carboxyl-terminal ends of the polypeptide chains.
The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.
The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).
Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN TYPE I and COLLAGEN TYPE III. It is a heterotrimeric molecule composed of alpha1(V), alpha2(V) and alpha3(V) subunits. Several forms of collagen type V exist depending upon the composition of the subunits that form the trimer.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Enzymes that catalyze the degradation of collagen by acting on the peptide bonds.
A class of Echinodermata characterized by long, slender bodies.
A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.
The anteriorly located rigid section of the PALATE.
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and often re-expressed in tumors. It is present in the central and peripheral nervous systems as well as in smooth muscle and tendons. (From Kreis & Vale, Guidebook to the Extracellular Matrix and Adhesion Proteins, 1993, p93)
Inflammation of a muscle or muscle tissue.
A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Fleshy and reddish outgrowth of skin tissue found on top of the head, attached to the sides of the head, and hanging from the mandible of birds such as turkeys and chickens.
Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
The region corresponding to the human WRIST in non-human ANIMALS.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.
A scleroprotein fibril consisting mostly of type III collagen. Reticulin fibrils are extremely thin, with a diameter of between 0.5 and 2 um. They are involved in maintaining the structural integrity in a variety of organs.
Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
A small leucine-rich proteoglycan found in a variety of tissues including CAPILLARY ENDOTHELIUM; SKELETAL MUSCLE; CARTILAGE; BONE; and TENDONS. The protein contains two glycosaminoglycan chains and is similar in structure to DECORIN.
Generalized or localized diffuse fibrous overgrowth of the gingival tissue, usually transmitted as an autosomal dominant trait, but some cases are idiopathic and others produced by drugs. The enlarged gingiva is pink, firm, and has a leather-like consistency with a minutely pebbled surface and in severe cases the teeth are almost completely covered and the enlargement projects into the oral vestibule. (Dorland, 28th ed)
Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
ENDOPEPTIDASES which use a metal such as ZINC in the catalytic mechanism.
A phylum of the most familiar marine invertebrates. Its class Stelleroidea contains two subclasses, the Asteroidea (the STARFISH or sea stars) and the Ophiuroidea (the brittle stars, also called basket stars and serpent stars). There are 1500 described species of STARFISH found throughout the world. The second class, Echinoidea, contains about 950 species of SEA URCHINS, heart urchins, and sand dollars. A third class, Holothuroidea, comprises about 900 echinoderms known as SEA CUCUMBERS. Echinoderms are used extensively in biological research. (From Barnes, Invertebrate Zoology, 5th ed, pp773-826)
A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.
The minute vessels that connect the arterioles and venules.
Contractile tissue that produces movement in animals.
The process of bone formation. Histogenesis of bone including ossification.
The farthest or outermost projections of the body, such as the HAND and FOOT.
Resistance and recovery from distortion of shape.
The occupational discipline of the traditional Chinese methods of ACUPUNCTURE THERAPY for treating disease by inserting needles along specific pathways or meridians.
COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I.
Fibroblasts which occur in the CORNEAL STROMA.
Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
A salt-soluble precursor of elastin. Lysyl oxidase is instrumental in converting it to elastin in connective tissue.
The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
The middle germ layer of an embryo derived from three paired mesenchymal aggregates along the neural tube.
A mucopolysaccharide constituent of chondrin. (Grant & Hackh's Chemical Dictionary, 5th ed)
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.
The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
An enzyme oxidizing peptidyl-lysyl-peptide in the presence of water & molecular oxygen to yield peptidyl-allysyl-peptide plus ammonia & hydrogen peroxide. EC
A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.
The application of knowledge to the food industry.
Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)
An extracellular endopeptidase of vertebrate tissues similar to MATRIX METALLOPROTEINASE 1. It digests PROTEOGLYCAN; FIBRONECTIN; COLLAGEN types III, IV, V, and IX, and activates procollagenase. (Enzyme Nomenclature, 1992)
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
Proteins prepared by recombinant DNA technology.
High molecular weight insoluble polymers which contain functional anionic groups that are capable of undergoing exchange reactions with cations.
The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)
Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.
A non-fibrillar collagen that forms a network of MICROFIBRILS within the EXTRACELLULAR MATRIX of CONNECTIVE TISSUE. The alpha subunits of collagen type VI assemble into antiparallel, overlapping dimers which then align to form tetramers.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Methods of preparing tissue for examination and study of the origin, structure, function, or pathology.
Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.
The least progressive form of SYSTEMIC SCLERODERMA with skin thickening restricted to the face, neck and areas distal to the elbows and/or knees, sparing the trunk. The CREST SYNDROME is a form of limited scleroderma.
High molecular weight, insoluble polymers which contain functional groups that are capable of undergoing exchange reactions (ION EXCHANGE) with either cations or anions.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.
A sulfated mucopolysaccharide initially isolated from bovine cornea. At least two types are known. Type I, found mostly in the cornea, contains D-galactose and D-glucosamine-6-O-sulfate as the repeating unit; type II, found in skeletal tissues, contains D-galactose and D-galactosamine-6-O-sulfate as the repeating unit.
Chronic inflammation and granuloma formation around irritating foreign bodies.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.
A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
The restriction of the MOVEMENT of whole or part of the body by physical means (RESTRAINT, PHYSICAL) or chemically by ANALGESIA, or the use of TRANQUILIZING AGENTS or NEUROMUSCULAR NONDEPOLARIZING AGENTS. It includes experimental protocols used to evaluate the physiologic effects of immobility.
Established cell cultures that have the potential to propagate indefinitely.
Proteoglycans consisting of proteins linked to one or more CHONDROITIN SULFATE-containing oligosaccharide chains.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)
An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS.
A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. It regulates TRANSFORMING GROWTH FACTOR BETA and ACTIVIN signaling.
A fibrous cord that connects the muscles in the back of the calf to the HEEL BONE.
A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
A disease characterized by bony deposits or the ossification of muscle tissue.
The part of the membranous labyrinth that traverses the bony vestibular aqueduct and emerges through the bone of posterior cranial fossa (CRANIAL FOSSA, POSTERIOR) where it expands into a blind pouch called the endolymphatic sac.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
A porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates to the canal of Schlemm.
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
A member of the metalloproteinase family of enzymes that is principally responsible for cleaving FIBRILLAR COLLAGEN. It can degrade interstitial collagens, types I, II and III.
The physiological renewal, repair, or replacement of tissue.
The forces and principles of action of matter and energy.
A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (From Dorland, 27th ed)

Destruction of hyaline cartilage in the sigmoid notch of the human ulna. (1/1596)

In an ulna from an adolescent a fossa nudata divided the articular surface of the sigmoid notch into olecranon and coronoid areas. In the floor of the fossa a layer of loose avascular pannus covered a thin layer of articular cartilage. The pannus appeared to have been formed by removal of chondroitin from the cartilage, freeing the cells and unmasking the fibres. Probably the change followed loss of contact between the articular cartilages of the sigmoid notch and trochlea during postnatal growth.  (+info)

Structural changes in intramuscular connective tissue during the fattening of Japanese black cattle: effect of marbling on beef tenderization. (2/1596)

We investigated changes in structures and mechanical properties of the intramuscular connective tissue during the fattening of Japanese Black steers, using the cell maceration method for scanning electron microscopy. During the early fattening period, from 9 to 20 mo of age, collagen fibrils of the endomysium in longissimus muscle associated more closely with each other, and collagen fibers in the perimysium increased in thickness and their wavy pattern became more regular. These changes were closely related to the increase in mechanical strength of the intramuscular connective tissue and resulted in a toughening of the beef during the period. The shear force value of longissimus muscle decreased after 20 mo of age, concomitantly with the rapid increase in the crude fat content. Scanning electron micrographs of the longissimus muscle dissected from 32-mo-old steers clearly showed that the adipose tissues were formed between muscle fiber bundles, that the honeycomb structure of endomysia was partially broken, and that the perimysium separated into thinner collagen fibers. In semitendinosus muscle, in which the crude fat content was lower (P<.05) than that in longissimus muscle, the structure of the intramuscular connective tissue remained rigid at 32 mo of age. The shear force value of the muscle increased even in the late fattening period, from 20 to 32 mo of age. Thus, the development of adipose tissues in longissimus muscle appears to disorganize the structure of the intramuscular connective tissue and contributes to tenderization of highly marbled beef from Japanese Black cattle during the late fattening period.  (+info)

Relationship between development of intramuscular connective tissue and toughness of pork during growth of pigs. (3/1596)

We investigated changes in structures and properties of the endomysium and perimysium during development of semitendinosus muscle in relation to the increase in toughness of pork using samples from neonates to 55-mo-old pigs. The shear force value of pork increased linearly until 6 mo of age, and the rate of increase slowed down thereafter. The secondary perimysium thickened owing to an increase in the number and thickness of perimysial sheets consisting of collagen fibers, which became thicker and wavy with the growth of the pigs. This increase in thickness of the secondary perimysium was correlated significantly with the increase in the shear force value (r = .98). The endomysial sheaths became thicker and denser in the muscle of 6-mo-old pigs. Maturation of the endomysium was accompanied by hypertrophy of muscle fibers. The amount of heat-soluble collagen decreased almost linearly, indicating that nonreducible cross-links between collagen molecules were formed throughout chronological aging. We conclude that thickening of the perimysium is closely related to an increase in the toughness of pork during growth of pigs.  (+info)

Interaction of Borrelia burgdorferi with peripheral blood fibrocytes, antigen-presenting cells with the potential for connective tissue targeting. (4/1596)

BACKGROUND: Borrelia Burgdorferi has a predilection for collagenous tissue and can interact with fibronectin and cellular collagens. While the molecular mechanisms of how B. burgdorferi targets connective tissues and causes arthritis are not understood, the spirochetes can bind to a number of different cell types, including fibroblasts. A novel circulating fibroblast-like cell called the peripheral blood fibrocyte has recently been described. Fibrocytes express collagen types I and III as well as fibronectin. Besides playing a role in wound healing, fibrocytes have the potential to target to connective tissue and the functional capacity to recruit, activate, and present antigen to CD4(+) T cells. MATERIALS AND METHODS: Rhesus monkey fibrocytes were isolated and characterized by flow cytometry. B. burgdorferi were incubated with human or monkey fibrocyte cultures in vitro and the cellular interactions analyzed by light and electron microscopy. The two strains of B. burgdorferi studied included JD1, which is highly pathogenic for monkeys, and M297, which lacks the cell surface OspA and OspB proteins. RESULTS: In this study, we demonstrate that B. burgdorferi binds to both human and monkey (rhesus) fibrocytes in vitro. This process does not require OspA or OspB. In addition, the spirochetes are not phagocytosed but are taken into deep recesses of the cell membrane, a process that may protect them from the immune system. CONCLUSIONS: This interaction between B. burgdorferi and peripheral blood fibrocytes provides a potential explanation for the targeting of spirochetes to joint connective tissue and may contribute to the inflammatory process in Lyme arthritis.  (+info)

Connective tissues: matrix composition and its relevance to physical therapy. (5/1596)

In the last 2 decades, the understanding of CT structure and function has increased enormously. It is now clear that the cells of the various CTs synthesize a variety of ECM components that act not only to underpin the specific biomechanical and functional properties of tissues, but also to regulate a variety of cellular functions. Importantly for the physical therapist, and as discussed above, CTs are responsive to changes in the mechanical environment, both naturally occurring and applied. The relative proportions of collagens and PGs largely determine the mechanical properties of CTs. The relationship between the fibril-forming collagens and PG concentration is reciprocal. Connective tissues designed to resist high tensile forces are high in collagen and low in total PG content (mostly dermatan sulphate PGs), whereas CTs subjected to compressive forces have a greater PG content (mostly chondroitin sulphate PGs). Hyaluronan has multiple roles and not only provides tissue hydration and facilitation of gliding and sliding movements but also forms an integral component of large PG aggregates in pressure-resisting tissues. The smaller glycoproteins help to stabilize and link collagens and PGs to the cell surface. The result is a complex interacting network of matrix molecules, which determines both the mechanical properties and the metabolic responses of tissues. Patients with CT problems affecting movement are frequently examined and treated by physical therapists. A knowledge of the CT matrix composition and its relationship to the biomechanical properties of these tissues, particularly the predictable responses to changing mechanical forces, offers an opportunity to provide a rational basis for treatments. The complexity of the interplay among the components, however, requires that further research be undertaken to determine more precisely the effects of treatments on the structure and function of CTs.  (+info)

Recombinant human type II collagens with low and high levels of hydroxylysine and its glycosylated forms show marked differences in fibrillogenesis in vitro. (6/1596)

Type II collagen is the main structural component of hyaline cartilages where it forms networks of thin fibrils that differ in morphology from the much thicker fibrils of type I collagen. We studied here in vitro the formation of fibrils of pepsin-treated recombinant human type II collagen produced in insect cells. Two kinds of type II collagen preparation were used: low hydroxylysine collagen having 2.0 hydroxylysine residues/1,000 amino acids, including 1.3 glycosylated hydroxylysines; and high hydroxylysine collagen having 19 hydroxylysines/1,000 amino acids, including 8.9 glycosylated hydroxylysines. A marked difference in fibril formation was found between these two kinds of collagen preparation, in that the maximal turbidity of the former was reached within 5 min under the standard assay conditions, whereas the absorbance of the latter increased until about 600 min. The critical concentration with the latter was about 10-fold, and the absorbance/microgram collagen incorporated into the fibrils was about one-sixth. The morphology of the fibrils was also different, in that the high hydroxylysine collagen formed thin fibrils with essentially no interfibril interaction or aggregation, whereas the low hydroxylysine collagen formed thick fibrils on a background of thin ones. The data thus indicate that regulation of the extents of lysine hydroxylation and hydroxylysine glycosylation may play a major role in the regulation of collagen fibril formation and the morphology of the fibrils.  (+info)

Altered connective tissue in children with congenital dislocation of the hip. (7/1596)

The umbilical cord was employed as a source of collagen in 10 children with congenital dislocation of hip. The amount of collagen and its solubility were measured in slices of the cords and in the umbilical veins and compared with the values in normal subjects. Both the amount of collagen and its solubility were decreased in children with congenital dislocation of the hip.  (+info)

Insulin regulation of amino acid transport in mesenchymal cells from avian and mammalian tissues. (8/1596)

Insulin regulation of amino acid transport across the cell membrane was studied in a variety of mesenchymal cell directly isolated from avian and mammalian tissues or collected from confluent cultures. Transport activity of the principal systems of mediation in the presence and absence of insulin was evaluated by measuring the uptake of representative amino acids under conditions approaching initial entry rates. Insulin enhanced the transport rate of substrate amino acids from the A system(alpha-aminoisobutyric acid, L-proline, glycine, L-alanine and L-serine) in fibroblasts and osteoblasts from chick-embryo tissues, in mesenchymal cells (fibroblasts and smooth muscle cells) from immature rat uterus, in thymic lymphocytes from young rats and in chick-embryo fibroblasts from confluent secondary cultures. In these tissues, the uptake of amino acid substrates of transport systems L and Ly+ (L-leucine, L-phenylalanine, L-lysine) was not affected by the presence of the hormone. No insulin control of amino acid transport was detected in chick-embryo chondroblasts and rat peritoneal macrophages. These observations identify the occurrence of hormonal regulatory patterns of amino acid transport for different mesenchymal cells types and indicate that these properties emerge early during cell differentiation.  (+info)

The most common connective tissue research in meat science has been conducted on the properties of intramuscular connective tissue of meat. The purpose of this study was to investigate histological properties of intramuscular connective tissues of left and right Quadriceps femoris muscle and Pectoralis superficialis muscles in the native chickens and the influence of sex on these properties. A total of 40 adult healthy native chickens (56 days) of both sexes (20 female and 20 male) were used. After fixation in 10% buffered formalin sections were prepared, using routine histological techniques. Tissue samples were stained with hematoxylin and eosin and a variety of special techniques for the determination of types of connective tissue fibers. The conventional histological study revealed that except the endomysium which was similar in both muscles, the other intramuscular connective tissues layers varied between leg and breast muscles and were affected by sex. All the connective tissue fibers ...
This is a loose connective tissue that consists of fat cells with little extracellular matrix. It stores fat for energy and provides insulation. LM × 800. (Micrograph provided by the Regents of University of Michigan Medical School © 2012) This is a loose connective tissue made up of a network of reticular fibers that provides…
These three types of fibers are combined in different levels to produced loose connective tissue with different properties. For example, if a tissue has more elastin it will be stretchy. If the tissue has more collagenous fibers it will be sturdy and strong.. ...
Connective tissue is the most abundant of the primary tissue types. Like epithelial tissue, connective tissue is widespread throughout the body, but its distribution within the different organs varies. In sharp contrast to epithelial tissue, which covers the body surface and lines its internal cavities and hollow organs, connective tissue is never exposed to the external environment. Depending on the type of connective tissue and its location, it (1) interconnects and fills the spaces between other tissues and organs; (2) protects, cushions, and provides structural support for other tissues and organs; (3) stores energy reserves in the form of neutral fats; and (4) transports substances throughout the body. Connective tissues encompass a wide variety of tissues in the body. For example, tendon, bone, fat, cartilage, and blood are all connective tissue structures. The principal feature of connective tissues that greatly distinguishes them from other tissues and is used to group them into a single ...
Development of the vertebrate musculoskeletal system requires the coordinated morphogenesis of muscle, muscle connective tissue, tendon, and skeleton. In the li...
Abundant research has been conducted on connective tissue rehabilitation, focusing on contracture reduction. The purpose of this study was to examine the diffe...
Connective tissues fulfil many functions but their primary function is a mechanical one, connective tissue elements being responsible for maintaining cells, tissues and organs in proper relationship to one another. They also provide the animal firstly with support, usually by means of a rigid skeleton, to which the softer tissues are attached and, secondly, with a system for the transmission of mechanical force, so that the contractile power of the muscles can be harnessed to the skeletal framework and used to move the animal as a coordinated whole. Connective tissues are essentially mesodermal in origin being derived from the primitive mesenchyme, a layer of the early embryo. They all contain the fibrous protein collagen, as their most important and characteristic constituent. Typical forms are tendon, the corium layer of the skin, loose connective tissue, cartilage and the basement membranes of various tissues. In a mineralized form connective tissue is present in calcified cartilage, bone, ...
Connective Tissue General structure of connective tissue Overview of connective tissue matrix Types of connective tissue Connective tissue composed of ground substance and protein fibers Mostly fluid connective tissue Source for information on Connective Tissue: The Gale Encyclopedia of Science dictionary.
A skeletal muscle consists of numerous muscle cells called muscle fibers. Three layers of connective tissues surround these fibers to form a muscle. These and other connective tissues associated with muscles follow. The endomysium is the connective tissue that surrounds each muscle fiber (cell). This blend can help in
The ILO is composed by a depression located on the lower surface of the liver, which is located posterior to the square lobe and anterior caudate lobe. Receive the neurovascular bundle directly to the liver and bile ducts made up primarily of two liver from the hepatic artery, the portal vein, some lymphatic vessels and nerves that make up the hepatic nerve plexus. Each beam structure is covered by the sheath of Glisson hepatobiliary, composed of loose connective tissue, the same one that covers the surface of the faces of the liver that accompanies each pot until the penetration in one or more liver segments. In the space between a vessel and the other is the loose connective tissue support. Just before entering the liver parenchyma, bile duct branches in the duct and right hepatic duct in the left hepatic duct, which then penetrate the hilum, these bile ducts are more anterior ducts of the hepatic hilum. Posteromedial to the two hepatic ducts, starting in the two branches of the hepatic artery ...
This is an easy slide from somebody with an infection.. Eosinophils are easier to see with a real microscope, but theres one here. You can spot an eosinophil by its: ...
The function of connective tissues depends on the organisation of their collagen fibres, arranged in parallel fibres, in parallel sheets (lamellae; annulus fibrosus, cornea, bone), or with more complex or random, orientation (cartilage, dermis, loose connective tissue).. My research is on roles of the cytoskeleton and cell-cell interactions in control of secretion and orientation of the extracellular matrix in fibrous connective tissues.. In tendons, longitudinal rows of fibroblasts are embedded between parallel collagen fibre bundles. Along a row, cells are connected by gap junctions made of connexins 43 and 32, and by adherens junctions. The adherens junctions link short lengths of actin stress fibres end to end from cell to cell along the cell row.. Gap junctions modulate cell response to load: antisense downregulation of of connexin 43 enhances, and connexin 32 depresses, matrix secretion. Adherens junction and stress fibre components are upregulated by load suggesting that cells may bind ...
I am curious to know that connective tissue you are referring to?. Connective tissue is not limited to ligaments and tendons.. Too, as fitness professionals, we re not in a position to know the health of an individuals connective tissues. We make the assumption that their connective tissue is healthy. We have no idea if some has some form of tendinopathy or whether certain ligaments are on the verge of rupture due to overuse.. In a healthy body exercises such as yoga and pilates among others can have a positive impact on connective tissue but the benefits are relative to the health of the connective tissue of the individual.. ...
Tendons= attaches Muscles to Bones.. Ligaments=attaches Bones to Bones.. Ligaments 1) ligaments(fibrous connective tissue) attaches Bones to Bones . 2) They are helpful in building up an entire bony structure, e.g our hand is made up of bones joined together by ligaments. Tendons 1) Tendons (fibrous connective tissues) attaches Muscles to Bones. 2) They are helpful in movement of bones, which are in contact to the muscles, hence helping us in contraction and relaxation of arms and legs muscles. https://medlineplus.gov/ency/imagepages/19089.htm Khan Acadmey!! Hope this Helps!! ^_^
Diarthroses are freely moveable joints (see Table 1). Diarthroses are also synovial joints because a cavity between the two connecting bones is lined with a synovial membrane and filled with synovial fluid, which helps to lubricate and cushion the joint.. Diarthroses are joined together by ligaments, which are made of fibrous connective tissue. Tendons are fibrous connective tissues that join muscles to bones. Tendons also help to stabilize joints, but they do not form joints. Bursae are fluid-filled sacs that help to reduce the friction between the tendons and ligaments and between the tendons and bones. The knee contains 13 bursae; inflammation in these sacs is called bursitis. What is commonly called tennis elbow is bursitis in the elbow.. Table 1: Types of Diarthroses (Synovial Joints). ...
fibrosis (es); Fibrosi (eu); fibrosi (ca); Fibrose (de); فیبروز (fa); 纤维化 (zh); 線維化 (ja); Fibros (sv); Фіброз (uk); Fibrosis (la); 섬유화 (ko); fibrozo (eo); Fibróza (cs); இழைநார்ப் பெருக்கம் (ta); Fibrosi (it); Fibrose (fr); Fibroza (hr); Xơ hóa (vi); Fibroza (sr); Fibrose (gl); לייפת (he); Fibrosis (id); Fibrosi (pl); fibrose (pt); Fibrose (nl); фіброз (be-tarask); Fibroza (bs); Фиброз (ru); Фиброза (bg); fibrosis (en); تليف (ar); Fibrosis (ms); Fibroz (uz) formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process (en); Ehun bat zuntzezko ehun bilakatzean datzan fenomenoa (eu); formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process (en) 線維症, 抗線維化, 抗線維化作用, 線維形成性 (ja); 纖維結締組織 (zh); التليف (ar ...
The intervertebral disc is basically made up of two parts and is often compared to a jelly donut. This donut-like structure is porous much like a sponge and (when healthy) is filled with fluid.. The center of this disc contains a jelly-like sack called the nucleus that - along with the fluid in the disc itself - acts like a hydraulic shock absorber.. The outer portion of the donut is called the annulus and is a series of concentric rings of fibrous connective tissue that surrounds the nucleus much like a ring of forts built one inside the other.. The top and bottom of the disc are capped with more of this fibrous connective tissue and these caps are called end plates. It should be noted that the end plates are strongly attached to the vertebrae above and below making it virtually impossible for the disc to slip.. ...
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As your feet age, your muscles, tendons, and ligaments may weaken or degrade, providing less support to the bones. This can lead to painful deformitie
The recovery period after anterior cruciate ligament (ACL) reconstruction surgery, and what you can expect long term, is different for every patient.
Anyone heard of Connective Tissue? Connective Tissue maintains the form of the body along with its internal organs, providing cohesion and support. It is a scaffolding for other cells to rest and where nerve tissue and muscle tissue are embedded. The entire body is supported from within by a skeleton composed of bone, a type of connective tissue able to resist stress due to its laminated structure and hardness. The individual bones of the skeleton are held firmly together by ligaments, and muscles are attached to bone by tendons, both of which are examples of dense connective tissue. At the joints, the bones are covered with cartilage, a connective tissue with a substance that gives it a consistency adapted to permitting smooth movements between surfaces. ...
Heating pork skin connective tissue (PCT) obtained from pork carcasses may enhance its water binding ability due to partial conversion of connective tissue collagen to gelatin. Upon cooling, the protein gel partially reforms, and may entrap added water. Incorporation of this recovered protein as a high added-water gel in reduced-fat products may improve product juiciness and palatability. The objectives of this study were to determine temperature and time variables that enhance conversion of connective tissue collagen to gelatin and determine basic properties of high added-water pork skin connective tissue gels. Heating PCT at 158oF for 30 minutes released more gel-water indicating conversion of connective tissue to gelatin. Added water (AW) levels of 100, 200, 300, 400, 500 and 600% were used to determine the water binding ability of heated PCT. Soluble collagen of these gels ranged from 100 to 25 mg/g, allowing the production of stable protein gels with as much as 600% AW. Increasing added water
Module 2 connective tissue and muscular system - The Term Paper on Connective Tissue Cell System Muscle... CONNECTIVE TISSUE CELLS- large matrix of protein (collagen) and polysaccharides Cartilage- found where
Intake of dietary sources of collagen may support the synthesis of collagen in varying tissues, with the availability of key amino acids being a likely contributor to its effectiveness. This study analyzed commonly consumed preparations of bone broth (BB) to assess the amount and consistency of its amino acid content. Commercial and laboratory prepared samples, made with standardized and variable (non-standardized) protocols were analyzed for key amino acids (glycine, lysine, proline, leucine, hydroxyproline and hydroxylysine). The main finding of the study was that amino acid concentrations in BB made to a standardized recipe were significantly lower for hydroxyproline, glycine, proline; P = 0.003 and hydroxylysine, leucine and lysine; P = 0.004 than those provided by a potentially therapeutic dose (20 g) of reference collagen supplements (P , 0.05). There was large variability in the amino acid content of BB made to non-standardized recipes, with the highest levels of all amino acids found ...
Fibrous tissues of the musculoskeletal system (e.g., the knee meniscus) are plagued by their poor intrinsic healing capacity. In the previous funding cycles, we...
These are notes taken from the site: http://www.biologyreference.com/ Connective Tissue The human body is composed of just four basic kinds of tissue: nervous, muscular, epithelial, and connective tissue Connective tissue is the most abundant, widely distributed, and varied type. It includes fibrous tissues, fat, cartilage, bone, bone marrow, and blood. As the name implies, connective tissues…
Ligaments come in a variety of forms and are integral parts of joints (ligare means to bind). They can serve as intrinsic binding structures constituting the substance of the joint itself, or as extrinsic supporting bands that stabilize joints while limiting their range of motion. While ligaments take on a variety of forms, they are generally described as dense irregular to dense regular collagenous connective tissue structures that bind one bone to another bone. The major exception to this rule is the occurrence of fibroelastic ligaments in certain locations. Ligaments are noncontractile tissues and they are typically damaged when they are stretched beyond their strength. Damage to these connective tissue structures is referred to as a sprain. Like muscle injuries, ligament injuries can be graded. Grade I sprains range from a stretch without a tear to a 20 percent tear of the ligaments collagen fibers. A grade II sprain involves tearing 20 to 75 percent of the ligament. Grade III sprains ...
Members of this family belong to the collagen superfamily [(PUBMED:8240831)]. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The sequence is predominantly repeats of the G-X-Y and the polypeptide chains form a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxyproline. Collagens are post-translationally modified by proline hydroxylase to form the hydroxyproline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure.. ...
Members of this family belong to the collagen superfamily [(PUBMED:8240831)]. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The sequence is predominantly repeats of the G-X-Y and the polypeptide chains form a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxyproline. Collagens are post-translationally modified by proline hydroxylase to form the hydroxyproline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure.. ...
Stromal cells are connective tissue cells of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa, prostate, bone marrow precursor cells, and the ovary as well as the hematopoietic system and elsewhere. These are the cells which make up the support structure of biological tissues and support the parenchymal cells.. Cadherin- ...
Connective tissues are main components of the animal body. Under the name of connective there is a wide variety of tissues (Figure 1), but sharing some common features. One of them is that connective tissues differentiated from mesenchyma (mostly coming from the embryo mesoderm). In addition, they show a remarkable extracellular matrix, which is a scaffolding made up of collagen and elastic fibers, glycoproteins, proteoglycans, glycosaminoglycans, and other molecules. The type and proportion of these components in the extracellular matrix set the structural, mechanical and biochemical properties of the different connective tissues. Extracellular matrix features and cell types define the variety of connective tissues. Connective tissues have been regarded as a supporting tissue because they connect and keep together many organs of the body, they provide mechanical support to different parts of the body and to the whole body as well, and protect and isolate many organs. Furthermore, they allow ...
The walls of all blood vessels, except the smallest, have three layers, or tunics, that surround a central blood-containing space, the vessel lumen.. The innermost tunic is the tunica intima. The tunica intima contains the endothelium, the simple squamous epithelium that lines the lumen of all vessels. The endothelium is continuous with the endocardial lining of the heart, and its flat cells fit closely together, forming a slippery surface that minimizes friction so blood moves smoothly through the lumen. In vessels larger than 1 mm in diameter, a subendothelial layer, consisting of a basement membrane and loose connective tissue, supports the endothelium.. The middle tunic, the tunica media, is mostly circularly arranged smooth muscle cells and sheets of elastin. The activity of the smooth muscle is regulated by sympathetic vasomotor nerve fibers of the autonomic nervous system and chemicals. Depending on the bodys needs at any given moment, regulation causes either vasoconstriction (lumen ...
treat varying depths of soft tissue. The purpose of the technique is to break up abnormalities within the muscles and ligaments such as excessive or problematic scar tissue that restricts motion. Loose connective tissue beneath the deep fascia, containing hyaluronic acid molecules, can become restricted following musculoskeletal injuries. The friction and temperature increase of IASTM helps normalize the hyaluronic acid and allow the fascial layers to glide freely. Immediate benefits may be noted after treatment such as reduction of pain and stiffness, and reduction of pain sensitivity. The benefits of IASTM are thought to be due to increases in circulation, removal of lymph congestion, modification of pain perception in the brain due to deep pressure application, and reduction of sensitivity in the treated area due to local release of platelet-derived growth factor.. A three-step approach used in IASTM:. ...
The disorganised scar tissue of fats cells, fibroblasts, inflammatory cells and loose connective tissue should be at the stage where it has been coaxed along to become something more functional. My ankle ligaments feel much stronger than they did a week ago. Its now at that stage that defines whether it stays as a mess that holds together, but without most of the elastic qualities a good a ligament has, or it becomes a functional ligament again. So this means training to encourage the remodelling process. There should be plenty of collagen now, and after the week and a bit of basic movement exercises most of it should be aligned in the right direction. The fibres will be type 3 collagen which are significantly thinner than the dense type 1 fibres which make up the majority of a healthy ligament. Into my fourth week post injury and I am running on the assumption the strength of my ligaments is at best 10-20%. Its a dangerous time. Without loading it will stagnate, but load al ...
Loose connective tissue, a. Photomicrograph of a mesentery spread stained with Verhoeff s hematoxylin to show nuclei and elastic fibers, counterstained with
The eyeball is almost spherical, but not perfectly so, mainly because its anterior, clear, or corneal segment has a greater curvature than the rest of the eye. Considering it as a globe, it has an anterior pole and a posterior pole; the former corresponding to the center of the front of the cornea, the latter to the center of the posterior curvature. An imaginary straight line joining, the two poles is called the axis of the eyeball. The equator of the eye is that part of its surface which lies midway between the two poles. The optic nerve joins the globe three or four mm to the nasal side of the posterior pole. The shape of the eye depends on, and is preserved by, the outermost tunic, formed conjointly by the cornea and sclera. All around the cornea there remains a little adherent conjunctiva; elsewhere, the sclera is directly exposed, except for some loose connective tissue which adheres to it, especially around the optic nerve entrance. In front of the equator we see the tendinous insertions ...
One or more tissue bulking devices are implanted to bulk a structure within a patient. The tissue bulking devices may be implanted between the structure and an adventitial layer that at least partially covers the structure, or within the adventitial layer. In some embodiments, the structure is a luminal wall that defines an inner lumen, and the bulking devices are implanted endoscopically via the lumen. In such embodiments, the tissue bulking devices may be implanted between a muscular layer of the luminal wall and an adventitial layer that at least partially covers the luminal wall, or within the adventitial layer. In exemplary embodiments, the luminal wall is the wall of the esophagus of the patient, and the tissue bulking devices are implanted proximate to the lower esophageal sphincter (LES) of the patient to treat gastroesophageal reflux disease (GERD).
Internal layer. This is vaginal mucosa. It is covered with stratified squamous epithelium, which forms many folds in the vagina (look at the picture, vagina seems tubular). When necessary vagina can change its size and stretch due to these folds.. Middle layer. This is smooth muscle layer of the vagina. Muscles are mostly longitudinal, but can have also circular direction. In its upper part, vaginal muscles transform into the uterine musculature. In the lower part of the vagina it becomes more durable, gradually connecting with the muscles of perineum.. Outer, or adventive layer. It is composed of loose connective tissue and components of muscle fibers.. Vaginal walls are divided into front and rear, connected one with another. The upper end of the vaginal wall covers the cervix, separating the vaginal part and forming so-called vaginal vault in the area around.. The lower end wall opens into the vagina threshold. Threshold of virgins is closed by hymen.. As we said before, the vagina is ...
Endocardium Myocardium Pericardium (or epicardium). The heart is a muscular organ that contracts rhythmically pumping the blood through the . Its walls consist of of three tunics or layers : the internal or endocardium , the middle or myocardium and the external or pericardium . The endocardium is homologous with the intima of the blood vessels. It consists of a single layer of squamous endothelial cells resting on a thin subendothelial layer of loose connective tissue. The myocardium is the thickest of the three tunics. It consists of cardiac muscle tissue. ...
which are usually attached to the basement membrane, and the food they provide more underlying loose connective tissue with blood vessels and nerves.All ions and energy substrates are held in the epithelial cells by diffusion through a thin-walled capillaries.. Classification and function According to the morphology and structural features to distinguish between epithelium is flat, cubic, cylindrical, multilayered, ciliary (ciliary) and gland.. In turn, all subtypes, except for the last, form a common group such as a coating, as delimit the body from the surrounding environment and carry out metabolism between them by suction and discharge.Also epithelium, including flat, protects all underlying layers from various damages: mechanical, chemical, physical, and others. In this regard, it has the high ability to regenerate in comparison to other body tissues.Especially great for the value of the skin and the respiratory tract because they are directly in contact with the external environment.Also, ...
Intestinal epithelial cells (IECs) overlying the villi play a prominent role in absorption of digested nutrients and establish a barrier that separates the internal milieu from potentially harmful microbial antigens. Several mechanisms by which antigens of dietary and microbial origin enter the body have been identified; however whether IECs play a role in antigen uptake is not known. Using in vivo imaging of the mouse small intestine, we investigated whether epithelial cells (enterocytes) play an active role in the uptake (sampling) of lumen antigens. We found that small molecular weight antigens such as chicken ovalbumin, dextran, and bacterial LPS enter the lamina propria, the loose connective tissue which lies beneath the epithelium via goblet cell associated passageways. However, epithelial cells overlying the villi can internalize particulate antigens such as bacterial cell debris and inert nanoparticles (NPs), which are then found co-localizing with the CD11c+ dendritic cells in the lamina
The stomach is the hollow organ that helps along digestion after mastication (chewing). It is the next step after the esophagus and before the small intestines.. Formation and Orientation. The stomach is composed of four parts. The cardia is the first part of the stomach in the digestive tract. It is the part of the stomach that allows the food to empty from the esophagus. The most northern part of the stomach is the Fundus. This section is the part that creates the curved part of the stomach. Next, the corpus or body is the piece of the stomach that holds most food as the stomach works to break it down. The last part is the Pylorus which is the passage that leads from the lower portion of the stomach to the small intestine.. The stomach is also made of many layers. The mucosa is comprised of the epithelium, loose connective tissues called the lamina propria, and the muscularis mucosae which is a thin layer of smooth muscle. The submucosa is beneath the mucosa. The Meissners plexus is in the ...
Structure. The glandular structure of the testis consists of numerous lobules. Their number, in a single testis, is estimated by Berres at 250, and by Krause at 400. They differ in size according to their position, those in the middle of the gland being larger and longer. The lobules (Fig. 91149) are conical in shape, the base being directed toward the circumference of the organ, the apex toward the mediastinum. Each lobule is contained in one of the intervals between the fibrous septa which extend between the mediastinum testis and the tunica albuginea, and consists of from one to three, or more, minute convoluted tubes, the tubuli seminiferi. The tubules may be separately unravelled, by careful dissection under water, and may be seen to commence either by free cecal ends or by anastomotic loops. They are supported by loose connective tissue which contains here and there groups of interstitial cells containing yellow pigment granules. The total number of tubules is estimated by Lauth at 840, ...
Allergic reactions with immediate effects are the result of antibody-antigen responses (i.e., they are the products of B-cell stimulation). These can be divided into three basic types.. Type I reactions, which include hay fever, insect venom allergy, and asthma, involve the class of antibodies known as immunoglobulin E (IgE). IgE molecules are bound to mast cells, which are found in loose connective tissue. When enough antigen has bound with the IgE antibodies, the mast cells release granules of histamine and heparin and produce other agents such as the leukotrienes. These potent chemicals dilate blood vessels and constrict bronchial air passages. Histamine is responsible for the visible symptoms of an allergic attack, such as running nose, wheezing, and tissue swelling. A severe, often fatal, type I allergic reaction is known as anaphylaxis. The predisposition of a person to type I allergic reactions is genetically determined. The best protection against such allergies is avoidance of the ...
see also pathophysiology topic 10. Pathophysiology of the lymphatic circulation). 1. Cardiac oedema. Often due to congestive heart failure.. This often leads to a type of subcutaneous oedema called pitting oedema. Pitting oedema is when you press on the oedema with one finger and there will be a finger-shaped depression. Another subcutaneous oedema is anasarca. However, cardiac condition can also lead to pleural effusions, ascites and pulmonary oedema. The latter one is often due to left ventricular failure but can also occur in renal failure.. 2. Pulmonary oedema. Lungs fills up with fluid causing them to be 2-3 heavier than their normal weight.. 3. Renal oedema. Like in nephrotic syndrome, there will be a loss to proteins because of proteinuria, as discussed earlier. This type of oedema manifests first in loose connective tissue, like the eyelids, giving preorbital oedema.. 4. Hepatic oedema. As discussed earlier, hypoproteinaemia due to impaired albumin synthesis. Also, hepatic hypertension ...
TY - JOUR. T1 - Finite element model of subsynovial connective tissue deformation due to tendon excursion in the human carpal tunnel. AU - Henderson, Jacqueline. AU - Thoreson, Andrew. AU - Yoshii, Yuichi. AU - Zhao, Kristin D. AU - Amadio, Peter C. AU - An, Kai Nan. PY - 2011/1/4. Y1 - 2011/1/4. N2 - Carpal tunnel syndrome (CTS) is a nerve entrapment disease, which has been extensively studied by the engineering and medical community. Although the direct cause is unknown, in vivo and in vitro medical research has shown that tendon excursion creates microtears in the subsynovial connective tissue (SSCT) surrounding the tendon in the carpal tunnel. One proposed mechanism for the SSCT injury is shearing, which is believed to cause fibrosis of the SSCT. Few studies have reported quantitative observations of SSCT response to mechanical loading. Our proposed model is a 2-D section that consists of an FDS tendon, interstitial SSCT and adjacent stationary tendons. We believe that developing this model ...
If bones are the steel frame of the body and cartilage forms the rubber shock absorbers between your bones, what name do we give for all the nuts, bolts, stitches, pulleys, cords, housings, laces, bindings, springs and bungees that connect our parts together?. These tough, durable attachment structures are provided by the dense connective tissues of the body. Like connective tissues in general, these tissues have few living cells (here, fibroblasts, shown traveling among the fibers). But in contrast to other connective tissues, the word dense here refers to an especially high density of collagen fibers. Collagen fibers provide a strong steel cable that is difficult to tear apart, and thus is used to provide tension resistance in body tissues. Collagen is such an important structural component that it makes up 25% of body protein - your most abundant protein of all.. There are three types of dense connective tissue:. ...
ObjectiveTo investigate pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans.Design and methodsSeventeen human hearts were studied. Group 1 consisted of control hearts (four hearts, weighing 280 ± 40 g each), from subjects wh
This is a study to determine how vaginal estrogen cream given for several weeks before pelvic reconstructive therapy will effect elastic fiber assembly in the muscularis layer of the vaginal wall. Postmenopausal women with at least Stage 2 pelvic organ prolapse will receive either estrogen vaginal cream or placebo cream 6-8 weeks prior to reconstructive surgery. At time of surgery, full thickness biopsies will be obtained from a standardized location at the top of vagina. The investigators will measure the thickness of the vaginal muscularis, elastic fiber number and morphology, and analyze if elastic fiber synthesis or degradation is affected by estrogen therapy. The results will provide important data to support a larger clinical trial to determine if preoperative and maintenance estrogen therapy alter long-term success rates of pelvic reconstructive surgery for pelvic organ prolapse ...
The development of complex musculoskeletal system requires essential interaction between muscles, bone, cartilage, soft connective tissue which includes tendons and ligaments and innervation of muscle by motor neurons. Tendon is a fibrous connective tissue that connects bone to muscle and bone to bone. Axial tendon progenitors arise from the syndetome in somites while limb tendons arise from lateral plate mesoderm. Scleraxis, a bHLH transcription factor is expressed in tendon cells. Meox2 has been shown to express in the limb mesoderm. In this study, we found that Meox2 is also necessary for the normal development of tendons and soft connective tissue. Meox2-/- neonatal mice had brittle, pale and thin tendons. Histological analysis showed mispatterned tendon tissue and reduced tendon mass. Using the Scleraxis-GFP reporter transgene, we found decreased expression of GFP in Meox2-/- in postnatal limb and tail tendons. In situ analysis of Scx RNA expression in Meox2-/- embryos confirmed the ...
Part I: Basic Concepts and Techniques Chapter 1: Properties of Dense Connective Tissue Chapter 2: Wound Healing: Injury and Repair of Dense Connective Tissue Chapter 3: Arthrology Chapter 4: Chronic Pain Management in the Adult Chapter 5: Assessment of Musculoskeletal Disorders and Concepts of Management Chapter 6: Introduction to Manual Therapy Chapter 7: Myofascial Considerations and Evaluation in Somatic Dysfunction Chapter 8: Soft Tissue Manipulations Chapter 9: Relaxation and Related Techniques Chapter 10: Functional Exercise Part II: Clinical Applications-Peripheral Joints Chapter 11: The Shoulder and Shoulder Girdle Chapter 12: The Elbow and Forearm Chapter 13: The Wrist and Hand Complex Chapter 14: The Hip Chapter 15: The Knee Chapter 16: The Lower Leg, Ankle and Foot Chapter 17: The Temporomandibular Joint Part III: Clinical-The Spine Chapter 18: The Spine-General Structure and Biomechanical Considerations Chapter 19: The Cervical Spine Chapter 20: The Thoracic Spine Chapter 21: The ...
You say skin rolling. I say connective tissue manipulation. Tomato…tomahto; semantics aside, lets talk about what it is and what it has to do with pelvic pain.. Skin rolling or connective tissue manipulation as Ill be referring to it throughout this post, is a major component of our pelvic pain treatment technique here at PHRC. Thats because in our experience treating pelvic pain patients-both male and female-more often than not, when there is pelvic pain, there will be some level of connective tissue restriction.. Before we delve into the connection (wink) between connective tissue restriction and pelvic pain, lets first explore exactly what connective tissue is.. Connective tissue is one of the four general classes of biological tissues-the others being epithelial, muscular, and nervous tissues. The job of connective tissue is to support, connect, or separate different types of tissue and organs.. Bones, ligaments, tendons, and cartilage are all considered connective tissue. ...
Heritable disorders of connective tissue are a heterogenous group of genetic conditions caused by defects of extracellular matrix elements such as collagen, elastin, mucopolysaccharides or related biomolecules. The genetic cause of many connective tissue disorders has been elucidated, while others are yet to be discovered or further defined. While clinical diagnostic criteria have been established for several of the connective tissue syndromes, many share features that overlap the known descriptions of other connective tissue disorders. Therefore, further characterization and phenotype/genotype correlation is needed to adequately diagnose and find treatments for these yet-to-be genotyped disorders.. An aim of this work is the examination of the cardiovascular, musculoskeletal and neurological complications of heritable connective tissue disorders (HDCT) and the natural history of these complications. Through mutational analysis for genes known to cause the HDCT, as well as identification of new ...
This human anatomy ClipArt gallery offers 54 illustrations of human connective tissues, including fibrous connective tissue (e.g., ligaments, tendons), cartilage, osseous tissue, and adipose tissue.. ...
Elements of any germinal layer may be present: Squamous epithelium or fibrous connective tissue covers the translucent dome of the myelomeningocele, which contains the neural placode. Meninges, blood vessels, and hyalinized connective tissue are found in the myelomeningocele, as well. On rare occasion, striated muscle, islands of cartilage, or epidermal cysts are included. Leptomeninges beneath the dermis typically have an alveolar rather than a membranous appearance (21).. ...
Fungiform papillae: Mushroom-like. Larger but much less frequent than filiform papillae. Has a stratified squamous non-cornified epithelial covering and a highly vascularized connective tissue core giving it a red hue in the living state. Although not seen here, the epithelium may contain taste buds. Small secondary papillae are formed beneath the superficial epithelial cover of the primary connective tissue papillae. Filiform papillae: Threadlike. Smaller and much more numerous than the fungiform variety. Epithelial lining is keratinized stratified squamous and is devoid of taste buds. Thin connective tissue core. Nerve fibers: Thinly myelinated sensory fibers that arborize under the epithelium. Fat cells: Part of the fatty (adipose) tissue underlying the lamina propria. Collagenous connective tissue: A fibrofatty connective tissue, which forms a bed for glands and skeletal muscle fibers and serves to anchor them. Serous gland acini: Mixed serous and mucous glands are scattered among the ...
The present study was conducted on five healthy indigenous male turkeys at the first year of their age and live weight was (4715 ± 43.3 gm) collected from the center of Diwanyia city, our need to have a base line data on the respiratory system of this abundant species of bird in Iraq. It is expected that this work will provide a pivot for future research and subsequent clinical application as regards the biology of the turkey.After birds preparation the trachea dissected out and washing by normal saline solution (0.9% Nacl), then were fixed immediately in 10% formalin, then get ready for routine histological processing.Trachea was lined by respiratory epithelium (ciliated, pseudostratified columnar epithelium) with simple branched tubular mucous glands and goblet cells. Laminapropria-submucosa of the trachea was supported by hyaline cartilages and comprised of loose connective tissue, with large bundles of collagen fibers.
Introduction: Long-term survival after heart transplantation (HTx) is hampered by cardiac allograft vasculopathy (CAV). Better understanding of the pathophysiological mechanisms of CAV might have considerable consequences for therapeutic approaches in the future. The aim of the present study was to investigate the histological phenotypes of CAV in relation with clinical ... read more patient characteristics. Methods and results: Coronary cross-sections from 51 HTx patients were obtained at autopsy. CAV was observed in 42 patients (82%). Three histological CAV phenotypes were identified (H-CAV 1-3). No CAV (H-CAV 0) is as seen in normal coronary arteries; intimal thickening consisting of a layer of longitudinal oriented smooth muscle cells. In H-CAV 1 to 3 a second intimal layer is formed, on top of the longitudinal oriented smooth muscle cell layer, with predominantly mononuclear inflammatory infiltrate in loose connective tissue (H-CAV 1), smooth muscle cells in different orientation (H-CAV 2), ...
Threaded io cialis levitra viagra free sample needles fig. Int j clin lab invest suppl, grace rf pulse oximetry spo, and vital organs is not associated with measles vaccine. Morton dr, klassen kp, curtis gm. Based on all continents and in so doing i found rigid and loose connective tissue and follow the instructions, or hides the true extent of infection can be diagnosed within months after the onset and diagnosis palpation of a large disc herniation facet joint cc. The lengthening shadow of andrew taylor still. Hypertensive encephalopathy is more apparent in the apophyseal joints due to being an osteopathic institution. Her body was found in patients with cardiac monitoring because of the data. An accurate history this information with or without electrical stimulation, local, systemic degenerative inflammatory immunologic respiratory, circulatory energy, metabolic endocrine infection somatic dysfunction lumbar somatic dysfunction.. real viagra cheap online If blinding of the presence of many ...
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Marian Blanca Ramírez from the CSIC in Spain has been studying the effects of LRRK2, a protein associated with Parkinsons disease, on cell motility. A Travelling Fellowship from Journal of Cell Science allowed her to spend time in Prof Maddy Parsons lab at Kings College London, learning new cell migration assays and analysing fibroblasts cultured from individuals with Parkinsons. Read more on her story here. Where could your research take you? The deadline to apply for the current round of Travelling Fellowships is 23rd Feburary 2018. Apply now!. ...
Looking for meniscofemoral ligaments? Find out information about meniscofemoral ligaments. strong band of white fibrous connective tissue connective tissue, supportive tissue widely distributed in the body, characterized by large amounts of... Explanation of meniscofemoral ligaments
Effects of massage unfortunately are usually short-term. We need to be careful to not oversell the benefits. That said it is generally agreed the most people benefit from massage. Blood flow is increased due to pressure and long rhythmic strokes. Increased circulation aides in the delivery of nutrients and oxygen to cells and tissues. It also aides in the excretion of metabolic wastes Blood pressure is decreased. In the same way the lymph flow is increased, reducing swelling and increasing the lymphocyte count which supports the immune system. Muscle tension is decreased because of increased blood supply and muscle stretching. Massage on connective tissue can prevent excessive scar formation, decrease adhesion formation and can release fascial restrictions. It can promote fracture healing and improves connective tissue healing. As result of the relaxing effect of massage sleep patterns are improved and digestion maybe stimulated. My last client (personal communication, April 1, 2009) commented ...
Connective tissue is the soft tissue that surrounds, supports, protects, and connects each and every structure in the body. A body contains a continuous sheath of connective tissue, which is called fascia. This sheath provides the structural support for the skeleton and soft tissues (muscles, tendons, etc.).. Gravity, injury, illness, emotional trauma, and other stress factors affect the fascia, causing an imbalance in the connective tissue network. Fascia imbalance usually manifests itself as tightening, or shortening of the connective tissue sheath (which makes your body feel as though because the muscles are extremely tight). This is often experienced as pain, stiffness, discomfort, or decreased flexibility anywhere in the body.. When the fascia becomes chronically shortened, it loses flexibility and resilience so your body cant relax completely, even when its at rest.. Connective tissue massage is the most direct way to restore length and flexibility throughout the entire muscular ...
Fibrosarcoma (fibroblastic sarcoma) is a malignant mesenchymal tumour derived from fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. It is usually found in males aged 30 to 40 .[citation needed] It originates in fibrous tissues of the bone and invades long or flat bones such as femur, tibia, and mandible. It also involves periosteum and overlying muscle. The tumor may present different degrees of differentiation: low grade (differentiated), intermediate malignancy and high malignancy (anaplastic). Depending on this differentiation, tumour cells may resemble mature fibroblasts (spindle-shaped), secreting collagen, with rare mitoses. These cells are arranged in short fascicles which split and merge, giving the appearance of fish bone known as a herringbone pattern. Poorly differentiated tumors consist in more atypical cells, pleomorphic, giant cells, multinucleated, numerous ...
We read, with much interest, the recent Research Article by Järvinen et al. (Järvinen et al., 2003), in which the authors show that, after removing the cast from an immobilized rat hind leg, within 8 weeks tenascin-C (TN-C) expression is increased in tendon and the myotendinous junction, but there is no de novo appearance of TN-C in skeletal muscle connective tissue. The authors extensively criticize our earlier paper (Flück et al., 2000), in which we concluded that loading of the chicken ALD muscle was sufficient to induce rapid ectopic TN-C expression in endomysial fibroblasts of skeletal muscle. Järvinen at al. argue that our results are merely caused by a response to muscle injury and the subsequent inflammatory reaction.. We would like to respond to these statements because the experiment by Järvinen et al. is so vastly different from ours that the conclusion, `Mechanical loading... does not induce de novo synthesis in the skeletal muscle, as stated in the title of their paper, is not ...
Osteoarthritis of the ankle usually occurs in ankles that have experienced trauma, infection, or injury. A smooth, slippery, fibrous connective tissue, called articular cartilage, acts as a protective cushion between bones. Arthritis develops as the cartilage begins to deteriorate or is lost. As the articular cartilage is lost, the joint space between the bones narrows. This is an early symptom of osteoarthritis of the ankle and is easily seen on X-rays.. As the disease progresses, the cartilage thins, becoming grooved and fragmented. The surrounding bones react by becoming thicker. They start to grow outward and form spurs. The synovium (a membrane that produces a thick fluid that helps nourish the cartilage and keep it slippery) becomes inflamed and thickened. It may produce extra fluid, which causes additional swelling.. As an alternative to surgery, fusion or replacement, Regenexx Procedures may help alleviate pain with a non-surgical injection procedure. Patients are often encouraged to ...
The superficial dermis in each of the skin sections on this slide is expanded by similar, unencapsulated, well-demarcated, collagenous masses that elevate the epidermis and widely separate hair follicles and adnexal glands. A small number of small arthropods are attached to the surface of the haired skin adjacent to the masses, and the superficial dermis is infiltrated by moderate numbers of inflammatory cells. The fibrous connective tissue of both masses consists of a regular arrangement of interlacing bundles that separate a moderate number of uniformly dispersed fibrocytes or small fibroblasts. The deep margin of one masses is infiltrated by a band of lymphocytes with a few plasma cells and macrophages. The lymphocytes are scattered within the deep portions of the mass, but they do aggregate more densely around a few veins and small arteries. Inflammatory ifiltrates in the other mass are loosely aggregated in the deep portions of the nodule, but also infiltrate the superficial portions of the ...
One of the most common consequences of the musculoskeletal disorder caused by pregnancy in the abdominal wall is the diastasis.. The abdominal diastasis (or diastasis of the rectums) is the separation of the rectus abdominis muscles (better known as those of the chocolate bar) due to stretching and consequent damage to the alba line, which is the fibrous connective tissue that joins the two rectus abdominis, which gives way to allow the growth of the fetus, leaving the abdomen looking flaccid.. The increase in this distance between these muscles can appear during the second trimester, but it is especially during the third trimester of pregnancy when the incidence is total.[1]. Natural recovery and the greatest decrease in diastasis occurs between the first day and the 8th week after delivery. When there is no decrease in the distance between the rectus abdominis in a natural way, we have to put ourselves in the hands of specialists to provide a solution since it is not just an aesthetic issue, ...
JPC SYSTEMIC PATHOLOGY. RESPIRATORY SYSTEM. August 2017. P-B10. Signalment ( #87-650): Rhesus monkey. HISTORY: This monkey was found dead in its cage.. HISTOPATHOLOGIC DESCRIPTION: SLIDE A: Lung: Up to 75% percent of the parenchyma is replaced by multifocal to coalescing granulomas composed of necrotic centers with occasional mineralization surrounded by numerous epithelioid macrophages, multinucleated giant cells (Langhans and foreign body type), and more peripherally by lymphocytes and plasma cells. Some granulomas are circumscribed by a thin fibrous connective tissue capsule. Multifocally, remaining alveolar septa are lined by hyperplastic type II pneumocytes. Alveolar spaces contain eosinophilic proteinaceous material (edema) admixed with numerous foamy alveolar macrophages, fewer lymphocytes, and scattered hemorrhage and fibrin. Multifocally, aggregates of lymphocytes and plasma cells surround blood vessels, which occasionally contain fibrin thrombi. Diffusely, the pleura is thickened to up ...
POTGIETER, N; ROBINSON, L e MIDDLETON, I. Hamartomas in the opercula of four unerupted primary molars. S. Afr. dent. j. [online]. 2018, vol.73, n.9, pp.577-579. ISSN 0375-1562. http://dx.doi.org/10.17159/2519-0105/2018/v73no9a7.. Odontogenic lesions in the opercula may result in delayed eruption of primary molars. CASE REPORT: This case presents a rare occurrence of delayed eruption of four primary molars causing interference with normal function. The lesions were surgically excised to expose the underlying first deciduous molars. Histopathological analysis of the excised tissue revealed hamartomatous lesions. These lesions appeared histologically identical to those of an odontogenic giant cell fibroma, consisting of odontogenic epithelial islands with scattered giant cells and histiocytes in a surrounding dense fibrous connective tissue stroma. Occasional dyskeratotic cells were also noted with an intermixed mild, chronic inflammatory cell infiltrate CONCLUSION: Eruption cysts are traditionally ...
Connective Tissue Disorder Site, info about Conditions and Diseases: Musculoskeletal Disorders: Connective Tissue: Connective Tissue Disorder Site
You may have a fibroid-or fibroids-and not even know it. They often dont cause symptoms. Many women have them sometime during their lives. And theyre surprised when their doctor discovers them during a routine exam.. Uterine fibroids are noncancerous growths. Theyre firm, compact tumors that are made of smooth muscle cells and fibrous connective tissue. They may be inside the uterus, on its outer surface, within its wall or attached to it by a stem-like structure. They range in size from undetectable to the eye to masses that can enlarge the uterus. They may grow slowly or quickly or remain the same size. Some go through growth spurts and some shrink on their own. You can have one fibroid or many. They arent associated with an increased risk of uterine cancer and never develop into cancer. Leiomyosarcoma, a rare form of cancer that most can affect the soft tissue of the uterus, starts as a single mutated muscle cell that is distinctly different from the mutations associated with fibroids. ...
Header}} {{Ref-Nonidez1941}} {, class=wikitable mw-collapsible mw-collapsed ! Online Editor  ,- , [[File:Mark_Hill.jpg,90px,left]] This historic 1941 textbook by Nonidez describes both embryology and histology. ,br> {{History Links}} ,br> Modern Notes: ,br> {{Histology_Links}} ,br> ,} {{Historic Disclaimer}} {{Nonidez1941 TOC}} =Part Three - The Organs= ==The Blood Vascular System== The tubular portions of the system (arteries, veins and capillaries) as well as the heart have a common and continuous lining of endothelium. In the thinnest vessels (capillaries) endothelium forms the entire wall. As the vessels become larger two more layers are added, namely: a middle muscular coat and an outer layer of fibrous connective tissue. The same three layers are found in the heart, in which the muscular coat is the most developed. ===I. The Blood Vessels=== A. Capillaries. Their diameter varies between 7 and iop. They form extensive networks whose meshes vary in size in the different organs. ...
Pain is the most prominent symptom of Fibromyalgia. It usually affects the entire body, although it may start in one area, such as the neck and shoulders, and spread to other areas over a period of time. Fibromyalgia is a form of generalized muscular pain and fatigue. The name, Fibromyalgia, means pain in the muscles and the fibrous connective tissues (the ligaments and tendons).. You (or someone you know) may be experiencing moderate or severe fatigue with a lack of energy, decreased exercise endurance, or the kind of exhaustion that results from the flu or lack of sleep. Sometimes the fatigue is more of a problem than the pain. Headaches, especially tension and migraine headaches, are common in Fibromyalgia. Abdominal pain, bloating, alternating constipation, bladder spasms, and irritability may cause urinary urgency or frequency. Your skin and blood circulation can be sensitive to temperature changes, resulting in temporary changes in skin color.. Have you suffered with for a few months, a ...
INTRODUCTION. Muscle fibers and extracellular intramuscular connective tissue are the main components of skeletal striated muscle. In order to identify types of fibers, the enzymatic activity is one of the characteristics that had permitted to classify myocytes according to their metabolism (oxidative, intermediate and glycolytic), velocity of contraction (slow twitch fibers, intermediate fibers and fast twitch fibers) and to molecular level, isoforms of myosin heavy chain (MHC-1, MHC-IIA, MCHIIB) (Purslow, 2010; de Freitas et al., 2009; Scott et al., 2001). Enzyme histochemistry techniques such as mATPase (myosin adenosine triphosphatase) and NADH-TR (nicotinamide adenine dinucleotide tetrazolium reductase), indicate in striated skeletal muscle tissue, fast twitch fibers that are associated with glycolytic and glycolytic-intermediate metabolism, while slow twitch fibers with oxidative metabolism (Vivo et al., 2004; Hebling et al., 2006; Carmo-Araújo et al., 2007; de Freitas et al.).. Modern ...
Fibrosarcoma (fibroblastic sarcoma) is a malignant mesenchymal tumour derived from fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. It is usually found in males aged 30 to 40. It ori
This medical illustration depicts cirrhosis of the liver. It emphasizes the increase in development of excess fibrous connective tissue in the liver.
Not to be confused with Granuloma. Proud flesh redirects here. For other uses, see Proud Flesh (disambiguation). Granulation tissue is the perfused, fibrous connective tissue that replaces a fibrin clot in healing wounds. Granulation tissue…
Granulation tissue Granulation tissue is the perfused, fibrous connective tissue that replaces a fibrin clot in healing wounds. Granulation tissue typically
People often make a mistake and believe that over shampooing or over ushing the hair can remedy the dandruff but it can actually be damaging to the hair. Does Dry Scalp Go Away On Its Own Dry Oily Roots Scalp and also hair falling. Acne dry skin hair that is pulled back into a For bacterial infections your physician may prescribe an antibiotic cream or pill. You can apply gram flour and curd as a home remedy to treat dandruff at home. There are many tried and tested psoriasis home remedies which one should try before even jumping to highly expensive medications. Goldwell Dualsenses Scalp Specialist Anti Dandruff 250 ml.. Inflammation of the outer skin and middle (muscle connective tissue and glands) portions of the eyelids is medically referred to as blepharitis. 1000s of Toy drones in stock. T Gel Daily curd and egg for dandruff zinc anti shampoo pureology scalpcure pyrithione Control 2 in 1 Dandruff Shampoo Plus Conditioner See ingredient review and recommendation. If so its likely not ...
Administration of triamcinolone diacetate to rats results in a decrease of prolyl hydroxylase activity in organs from animals of different ages. The response of the enzyme activity is dose-dependent, reversible, independent of endocrine function (except for the response of the liver enzyme in hypophysectomized rats), and dependent on the number of daily injections. The decrease in enzyme activity is paralleled by a decrease in the amount of enzyme protein as measured by immunoassay. These results indicate that prolyl hydroxylase is decreased in a wide spectrum of tissues following administration of anti-inflammatory steroids. Furthermore, these findings suggest that one of the effects of this class of therapeutically used drugs on connective tissue metabolism may be mediated by a decrease in the prolyl hydroxylation step of collagen biosynthesis.. ...
Men and women possess a different connective tissue structure at the first layer of subcutaneous fat. The adipose tissue in females is contained in chamber-like structures that supports the expansion of the adipose tissue into the dermis. On the contrary, mens connective tissue architecture is criss-cross which allow for the subcutaneous fat to expand laterally and internally with little to no protrusion into the dermis. Men also have a thicker epidermis and dermis tissue layers in the thighs and buttocks. Hormone variations can differ between genders and according to some researchers, can cause subcutaneous fat cell appearance similar to females in men who are born deficient in male hormones. See more on The Cellulite Solution: A Doctors Program for Losing Lumps, Bumps, Dimples, and Stretch Marks.. ...
The following is taken verbatim from a hand-out at the World Conference on Breast Cancer.. Breast Cancer: Prevent and Survive it with Iodine. Presentation by David M. Derry, MD, PhD. Dr. Derry believes that breast cancer can be treated effectively. He will discuss:. What causes breast cancer. How cancer spreads. How thyroid hormones strengthen the connective tissue cancer barrier. How adequate iodine intake can reduce breast cancer to a controllable chronic disease of little significance. Hypothesis:. Cancer development has two phases - one controlled by iodine, and the other by thyroid hormone. Using this two-phase hypothesis, we can better understand fibrocystic disease and breast cancer. Supplemental iodine in correct doses triggers apoptosis or natural cell death, which destroys abnormal cells that are in the process of becoming cancer cells, and even kills some early cancer cells. Adequate thyroid hormone blocks cancer cells from spreading through connective tissue.. With optimum amounts ...
When people hear about the idea of stressing joints, their hackles go up. They worry about overstretching dense connective tissues and ligaments. Ive noticed that this fear often comes from confusing stress with stretch. Stressis force applied to something, in this case our joint tissue. Stretch is the subsequent lengthening that occurs due to the stress placed on that tissue. But not all stress causes stretch. And in Yin Yoga, the intention is to safely and moderately stress our joints to promote the health of the tissues in and around our joints - not to overly lengthen these tissues. In Yin Yoga, great care is given to observing the kinds of sensations one experiences, emphasizing the mild end of the sensation spectrum - not pushing, pulling, or striving to go deeper, and always avoiding any signal of pain. Practiced intelligently, Yin Yoga is a tissue-specific exercise, and shouldnt be approached with the mindset of more is better. Of course, as with any yoga style, people might ...
Terminal pad - Lies at anterior end of club (i.e., distal to the dactylus (when present)); consists of 1-20 or so, smooth ringed suckers. All suckers are often tightly packed together in an oval or slightly elongate shape and have short, approximately equal-sized stalks. A flap of skin curves over the distal edges of the pad. The aboral side of the pad contains what appears to be a thick dermis of dense connective tissue not found elsewhere on the club. The function of the terminal pad as a distal locking-mechanism is known, from experimental evidence, only in loliginids (loliginids lack a carpus): As the tentacles elongate, they twist so that the suckers face outward and the tips of the clubs remain attached (Keir and van Leeuwen, 1997, an experimental analysis of Loligo pealei attacking a tethered shrimp). In oegopsids the terminal pad seems to act as a distal locking-mechanism to help hold the clubs together, at least, when not in use (see photographs below). The locking mechanism differs ...
Parasitol, foxia Dense connective tissue plate in each eyelid Contains meibomian glands 29 mm long and 1 augmentin allergy ancef thick; tapered at ends Rigid attachments to eriosteummediall laterally пппFigure 6-14.
Connective tissue is the material that supports the organs in your body. It gives your tissues shape and strength. There are over 200 disorders that affect connective tissue. Together, they are known as connective tissue disorders, or CTDs.
Collagens are the fundamental structural proteins in vertebrates, where they fulfill a variety of critical roles in connective tissue structure and mechanics. As such, alterations in collagens composition, resulting from genetic modifications, aging, and diabetes, have been identified with an extensive list of diseases [1, 2]. Additionally, due to their natural role as the structural component in the extracellular matrix, collagens have found widespread use in biomaterials, used for cellular and tissue engineering, drug delivery, and a wide range of other applications [3-5].. Most studies on collagens use protein extracted from animal tissues. While this provides a large-scale supply of the protein, the lack of control over protein composition has its drawbacks. For example, there is minimal ability to select protein sequence, since generally type I collagen is most easy to extract and its sequence varies little among different animal species. Furthermore, because posttranslational ...
Tendinitis Tendinitis is inflammation of a tendon-the flexible connective tissue structures that connect your muscles to your bones. Inflammation is the localized response by your body to injury or damage caused by chemical, physical, or biological agents. Most tendinitis treated by podiatrists and other healthcare providers is caused by tendon overuse, most commonly associated with athletic endeavors. Tendinitis in your feet and lower extremities can significantly impair your ability to perform your activities of daily living ...
A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis. - National Library of Medicine Medical Subject Headings 2000
Although a few pathogens cause most surgical infections, many organisms are capable of doing so. Among the aerobic organisms, streptococci may invade even minor breaks in the skin and spread through connective tissue planes and lymphatics. Staphylococcus aureus is the most common pathogen in wound infections and around foreign bodies. Klebsiella often invades the inner ear and enteric tissues as well as the lung. Enteric organisms, especially the Enterobacteriaceae and enterococci, are often found together with anaerobes. Among the anaerobes, bacteroides species and Peptostreptococci are often present in surgical infections, and clostridium species are major pathogens in ischemic tissue. ...
... can be broadly classified into connective tissue proper, and special connective tissue. Connective tissue ... Connective tissue is one of the four primary types of animal tissue, along with epithelial tissue, muscle tissue, and nervous ... Fibromuscular tissue is made up of fibrous tissue and muscular tissue. New vascularised connective tissue that forms in the ... Other kinds of connective tissues include fibrous, elastic, and lymphoid connective tissues. Fibroareolar tissue is a mix of ...
A connective tissue nevus may be present at birth or appear within the first few years, is elevated, soft to firm, varying from ...
Mixed connective tissue disease - Mixed connective-tissue disease (MCTD) is a disorder in which features of various connective- ... A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology ... Merck Manual: Musculoskeletal and connective tissue disorders Merck Manual: Inherited connective tissue disorders Arthritis ... Undifferentiated connective tissue disease (UCTD) is a disease in which the body mistakenly attacks its own tissues. It is ...
A connective tissue neoplasm or connective tissue tumor is a neoplasm arising from the tissues of the connective tissue. (Not ... all tumors in the connective tissue are of the connective tissue.) Zelger, Bernhard (2002). "Connective tissue tumors". Recent ... Tissues (biology), Connective and soft tissue neoplasms). ...
It is classified as either dense regular connective tissue or dense irregular connective tissue. Loose connective tissue "Blue ... Dense connective tissue, also called dense fibrous tissue, is a type of connective tissue with fibers as its main matrix ... TermsCells&Tissues/connective/dense/dense1 - Comparative Organology at University of California, Davis - "Connective tissue, ... Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets. ...
... is a subset of connective tissue proper. Furthermore, areolar tissue is the same as loose connective ... Loose connective tissue, sometimes called areolar tissue, is a cellular connective tissue with thin and relatively sparse ... They join connective tissues to other tissues. Areolar tissue (/əˈriːələr/ or /ˌɛəriˈoʊlər, ˌær-/) is a common type of loose ... Areolar connective tissue holds organs in place and attaches epithelial tissue to other underlying tissues. It also serves as a ...
... is a type of connective tissue with a network of reticular fibers, made of type III collagen ( ... Reticular connective tissue resembles areolar connective tissue, but the only fibers in its matrix are reticular fibers, which ... "Connective tissue, reticular (LM, Medium)" Histology at uwa.edu.au (Connective tissue). ... Reticular connective tissue is found around the kidney, liver, the spleen, and lymph nodes, Peyer' patches as well as in bone ...
... (also called mutable collagenous tissue) is a kind of connective tissue found in echinoderms (such as ... Connective tissue, including dermis, tendons and ligaments, is one of four main animal tissues. Usual connective tissue does ... This connective tissue is specific to echinoderms in which it works in posture maintenance and mechanical defense with low ... Catch connective tissue is found in all the extant classes of echinoderms. Sea lilies and feather stars: ligaments connecting ...
DRCT is divided into white fibrous connective tissue and yellow fibrous connective tissue, both of which occur in two forms: ... Dense regular connective tissue (DRCT) provides connection between different tissues in the human body. The collagen fibers in ... "Dense regular connective tissue". www.pc.ctc.edu. Archived from the original on 2009-09-25. Retrieved 2009-10-16. "What Are ... Dense regular connective tissue has great tensile strength that resists pulling forces especially well in one direction. DRCT ...
... (UCTD) is a disease in which the body mistakenly attacks its own tissues. It is ... Connective tissue diseases, Systemic connective tissue disorders). ... August 2009). "Undifferentiated connective tissue disease: a seven-center cross-sectional study of 184 patients". Clinical ... June 2011). "Undifferentiated connective tissue disease presenting with prevalent interstitial lung disease: Case report and ...
... has fibers that are not arranged in parallel bundles as in dense regular connective tissue. ... Dense irregular connective tissue consists of mostly collagen fibers. It has less ground substance than loose connective tissue ... "Connective Tissue". Archived from the original on 2008-11-07. Retrieved 2008-11-27. "Dense irregular connective tissue". ... Fibroblasts are the predominant cell type, scattered sparsely across the tissue. This type of connective tissue is found mostly ...
In dentistry, the subepithelial connective tissue graft (SECT graft, and sometimes referred to simply as a connective tissue ( ... describes how the individual who receives the graft is the same individual who provides the donor tissue. The connective tissue ... Because the connective tissue for the graft is transplanted without the superficial epithelium from the donor site, it is ... At the donor site, Edel described three methods for choosing and preparing the donor site to obtain connective tissue for the ...
... is a rare condition, and often occurs on the upper or lower extremities. Involutional ...
"Mixed Connective Tissue Disease, MCTD". The Free Dictionary by Farlex. Nevares AM, Larner R. "Mixed Connective Tissue Disease ( ... "Definition and diagnosis of mixed connective tissue disease". Alves, Marta (2020). ""Mixed connective tissue disease": a ... "Mixed Connective Tissue Disease (MCTD)". MedicineNet.com. Nevares AM, Larner R. "Mixed Connective Tissue Disease (MCTD): ... Connective tissue diseases, Disorders of fascia, Systemic connective tissue disorders, Autoimmune diseases). ...
710 Diffuse diseases of connective tissue 710.0 Systemic lupus erythematosus 710.2 Sjögren's syndrome 710.3 Dermatomyositis ... Diseases of the Musculoskeletal System and Connective Tissue. It covers ICD codes 710 to 739. The full chapter can be found on ... 710.4 Polymyositis 710.5 Eosinophilia myalgia syndrome 710.9 Connective tissue disease, unspec. 711 Arthropathy associated with ... unspecified 729.3 Panniculitis unspecified 729.4 Fasciitis unspecified 729.5 Pain in limb 729.6 Foreign body in soft tissue ...
Rubbelke DL (1999). "Connective Tissue Proper". Tissues of the Human Body: An Introduction. McGraw-Hill Companies. v t e (CS1 ... ISBN 978-1-118-34500-9. "Connective Tissue". Self Study Unit of the Basic Tissues. University of Ottawa. Archived from the ... Dense connective tissue has a smaller amount of ground substance compared to the fibrous material. The meaning of the term has ... Loose connective tissue is characterized by few fibers and cells, and a relatively large amount of ground substance. ...
"Connective Tissue". Art Practical. Retrieved 2021-06-05.{{cite journal}}: CS1 maint: url-status (link) Mukherjee, Ranu (2019-07 ...
Connective Tissue Research. 25 (2): 103-119. doi:10.3109/03008209009006985. ISSN 0300-8207. PMID 2175692. Wikidata Q43601010. ...
Connective Tissue Research. 44 (1): 20-25. doi:10.1080/713713602. PMID 12952169. Pyura pachydermatina discussed in RNZ Critter ... Connective Tissue Research. 34 (4): 263-269. doi:10.3109/03008209609005270. PMID 9084635. "Pyura". Biosecurity in New Zealand. ... The tissues of this tunicate are strengthened by the presence of two types of spicules. In the blood vessels in the tunic there ... Aizenberg, J.; Weiner, S.; Addadi, L. (2003). "Coexistence of amorphous and crystalline calcium carbonate in skeletal tissues ...
Connective Tissue Research. 20 (1-4): 313-9. doi:10.3109/03008208909023902. PMID 2612162. Wozney JM, Rosen V, Celeste AJ, ... It is highly expressed in fractured tissues. BMP3 is hypermethylated in many cases of colorectal cancer (CRC) and hence along ... and tissue inhibitors in human fetal, adult, and osteoarthritic articular cartilage". Journal of Orthopaedic Research. 22 (6): ...
Okamoto O, Fujiwara S (2006). "Dermatopontin, a novel player in the biology of the extracellular matrix". Connective Tissue ... The extracellular matrix (ECM) is known as a non-cellular component that is found in all organs and tissues. The ECM provides ... The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is a component of the ... while in tissues, Fn perform as an activated and collected into the Fn matrix (a fibrillar structure) that discovered during ...
McKee MD, Nanci A (1996). "Osteopontin: an interfacial extracellular matrix protein in mineralized tissues". Connective Tissue ... Connective Tissue Research. 44 (Suppl 1): 33-40. doi:10.1080/03008200390152061. PMID 12952171. S2CID 29910722. Christensen B, ... The prefix osteo- indicates that the protein is expressed in bone, although it is also expressed in other tissues. The suffix - ... Da Silva AP, Pollett A, Rittling SR, Denhardt DT, Sodek J, Zohar R (September 2006). "Exacerbated tissue destruction in DSS- ...
... and connective tissue (bone fibers). Scrutiny under the microscope further revealed that the putative dinosaur soft tissue had ... 2003). "Identification of Proteinaceous Material in the Bone of the Dinosaur Iguanodon". Connective Tissue Research. Milton ... After recovery, the tissue was rehydrated by the science team. When the fossilized bone was treated over several weeks to ... This included even more detailed tissue, down to preserved bone cells that seem to have visible remnants of nuclei and what ...
Connective Tissue Research. 41 (1): 29-36. doi:10.3109/03008200009005639. ISSN 0300-8207. PMID 10826706. S2CID 34511081. ... This phenomenon was discovered in 1912, and the terminology was introduced in 1945, but it is with the development of tissue ... Weiss, Paul (December 1945). "Experiments on cell and axon orientation in vitro: The role of colloidal exudates in tissue ... Similarly, the collagen fibers present in collagen gels and soft tissues can influence cell alignment, providing the most ...
Boskey AL (2003). "Biomineralization: an overview". Connective Tissue Research. 44 (Supplement 1): 5-9. doi:10.1080/713713622. ... often to harden or stiffen existing tissues. Such tissues are called mineralized tissues. It is an extremely widespread ... Currey JD (December 1999). "The design of mineralised hard tissues for their mechanical functions". The Journal of Experimental ... Murdock DJ, Donoghue PC (2011). "Evolutionary origins of animal skeletal biomineralization". Cells Tissues Organs. 194 (2-4): ...
C: Connective tissue. A dense subcutaneous layer of fat and fibrous tissue that lies beneath the skin, containing the nerves ... The 'danger area of the scalp' is the area of loose connective tissue. This is because pus and blood spread easily within it, ... L: The loose areolar connective tissue layer provides an easy plane of separation between the upper three layers and the ... A knife with multiple blades is used to remove tissue from donor areas. The removed tissue is then fragmented into smaller ...
... with a specific interest in how the connective tissue of blood vessel walls changes with age. She carried out seminal work on ... Connective Tissue Research. 15 (1-2): 3-7. doi:10.3109/03008208609001966. ISSN 0300-8207. PMID 2944699. Rall, Jack A. (2018-04- ... an enzyme capable of degrading the protein elastin which gives tissues like veins their flexibility. She also contributed to ...
Connective Tissue Research. 40 (1): 1-11. doi:10.3109/03008209909005273. PMID 10770646. Strober, Warren; Fuss, Ivan J. (May ... Both CD4+ and CD8 IL-17 producing T cells have been shown to cause aTH1, causing tissue inflammation and resulting in severe ... Cytokines derived from adipose tissue serve as remote regulators such as hormones. Studies have shown that TNF-α and IL-6 ... A proinflammatory cytokine causes hyperinflammation, the leading cause of lung tissue destruction in cystic fibrosis. With such ...
Boskey AL (2003). "Biomineralization: an overview". Connective Tissue Research. 44 Suppl 1 (1): 5-9. doi:10.1080/713713622. ... produced by epithelial tissues in most animals. Mucins' key characteristic is their ability to form gels; therefore they are a ... colon and other tissues. Mucins are also overexpressed in lung diseases such as asthma, bronchitis, chronic obstructive ...
Connective Tissue Research. 44 (Suppl. 1): 41-46. doi:10.1080/03008200390152070. PMID 12952172. S2CID 2249126. Paul, Gregory S ... only noting on page 69 that there is no hard-tissue evidence for venom in stingray tails and platypus spurs. Elting and Goodman ...
Together, they published a monograph on the vital staining of connective tissue cells. The discovery of Vitamin E came as a ... On the differential reaction to vital dyes exhibited by the two groups of connective-tissue cells. Washington, D.C.: Carnegie ... Herbert Mclean On the differential reactions to vital dyes exhibited by the two great groups of connective-tissue cells. ...
Development proceeds and the oogonia become fully surrounded by a layer of connective tissue cells (pre-granulosa cells). In ... There are also developments of other tissues from the mesonephric duct that persist, e.g. the development of the suspensory ... and the corpus spongiosum penis arise from the mesodermal tissue in the phallus; they are at first dense structures, but later ...
... can also present in the setting of nontraumatic inflammatory injury of auricular connective tissue such as in ... Consequently, the concave pinna fills with disorganized connective tissue. The cartilage then deforms and kinks, resulting in ... Risk of necrotic tissue is greatest when both posterior and anterior surfaces are involved, although posterior surface ... causing it to die and resulting in the formation of fibrous tissue in the overlying skin. As a result, the outer ear becomes ...
Peritendinous tissues become macroscopically thickened and new connective tissue adhesions occur. In paratenonitis, ... Soft tissue, Skeletal system, Tendons, All stub articles, Musculoskeletal disease stubs). ...
Sjorgen's syndrome not associated with other health problems or connective tissue diseases) is hyper-methylated at its CpG ... Studies have reported that: 1) the levels of CMTM5-v1 in the malignant tissues of patients with prostate cancer are lower than ... the levels in their nearby normal prostate gland tissues as well as in the tissues of patients with benign prostate hyperplasia ... 2) patients with lower prostate cancer tissue levels of CMTM5-v1 have higher prostate cancer Gleason scores and therefore ...
... the connective tissue, blood and other non-fat content must be removed. It then must be coarsely grated. It must be ...
... are infections of skin and associated soft tissues (such as loose connective tissue and mucous membranes).[citation needed] ... Skin and skin structure infections (SSSIs), also referred to as skin and soft tissue infections (SSTIs), or acute bacterial ... microbiologic evaluation using tissue culture has been demonstrated to have high utility in guiding management decisions. There ... "Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases ...
As tendons develop they lay down collagen, which is the main structural protein of connective tissue. As tendons pass near bony ... Tendons are cords of connective tissue attaching muscle to bone, cartilage or other tendons. They are a major contributor to ... In equine ovaries, unlike in humans, the vascular tissue is cortical to follicular tissue, so ovulation can only occur at an ... Scar tissue within the tendon decreases the overall elasticity in the damaged section of the tendon as well, causing an ...
Connective/soft tissue tumors and sarcomas, All stub articles, Neoplasm stubs, Pathology stubs, Oncology stubs). ... They consist of epithelial tissue, and stromal or mesenchymal tissue. They may be benign or malignant. Examples include: ...
... poses apply moderate stress to the connective tissues of the body-the tendons, fasciae, and ligaments-with the aim of ... These areas are especially rich in connective tissues, the "loading" of which (Yin Yoga teachers avoid the word "stretching") ... In the body, the relatively stiff connective tissues (tendons, ligaments, fascia) are considered yin, while the more mobile and ... Taoist-based practice targets the connective tissues, ligaments, joints and synovial fluid". Los Angeles Times. Pizer, Ann (17 ...
... also known as hexabrachion-like protein is a glycoprotein that is expressed in connective tissues including skin, joints and ... miR-137 is epigenetically silenced in colorectal adenomatous tissues to the same extent as in colorectal cancer tissues, ...
... connective tissues in fishes and theropods or insect wings). Most of the osteological features of the holotype became apparent ... stagnation and the action of microbial mats in the locality that have yielded a wide variety of examples of soft-tissue ... "The mineralization of dinosaur soft tissue in the Lower Cretaceous of Las Hoyas, Spain", Journal of the Geological Society, vol ...
Occasionally, this inflammation can cause scar tissue to form on Glisson's capsule, a thin layer of connective tissue ...
Myofascial pain is pain in muscles or fascia (a type of connective tissue that surrounds muscles). It can occur in distinct, ... connective tissue) constrictions. It can appear in any body part. Symptoms of a myofascial trigger points include: focal point ... such as connective tissue disease, can cause MPS. Poor posture and emotional disturbance might also instigate or contribute to ... Soft tissue disorders, Ailments of unknown cause, Disorders of fascia, Pain, Chronic pain syndromes, Rheumatology, Urologic ...
The connective tissue between the lobes of the anthers extends upward to form a disc-shaped cap. Its flowers have 2-7 carpels ...
... syndrome Congestive heart failure Conjunctivitis ligneous Conjunctivitis with pseudomembrane Conjunctivitis Connective tissue ... Cohen syndrome Camfak syndrome Campomelia Cumming type Camptobrachydactyly Camptocormism Camptodactyly fibrous tissue ...
Connective tissue: The term used by Kornheiser to describe the robust community and connections created by the show in an ...
... mixed connective tissue disease, poststreptococcal glomerulonephritis, rheumatoid arthritis, and systemic sclerosis. Less ...
... is an association between familial thoracic aortic aneurysm and Marfan syndrome as well as other hereditary connective tissue ...
The sponge body is mostly a connective tissue; the mesohyl, over which are applied epithelioid monolayers of cells, the outer ...
... spindle-shaped or star-shaped fibroblasts and ectatic blood vessels in a dense collagen fiber connective tissue background. In ... Sobanko JF, Dagum AB, Davis IC, Kriegel DA (June 2007). "Soft tissue tumors of the hand. 1. Benign". Dermatologic Surgery. 33 ( ... The treatment of KTs has varied depending on their size, numbers, locations, symptoms, damage to tissues, and disfiguring ... Paral KM, Petronic-Rosic V (2017). "Acral manifestations of soft tissue tumors". Clinics in Dermatology. 35 (1): 85-98. doi: ...
As well as glands, the seminal vesicles contain smooth muscle and connective tissue. This fibrous and muscular tissue surrounds ... They do not cause elevation of tumour markers, and are usually diagnosed based examination of tissue that has been removed ... Adenocarcinomata are usually diagnosed after they are excised, based on tissue diagnosis. Some produce the tumour marker Ca-125 ... The tissue of the seminal vesicles is full of glands, spaced irregularly. ...
The segments are separated from each other by layers of connective tissue that forms them into discrete anatomical and ...
Skeletal muscle includes skeletal muscle fibers, blood vessels, nerve fibers, and connective tissue. Skeletal muscle is wrapped ... Striated muscle tissue is a muscle tissue that features repeating functional units called sarcomeres. The presence of ... Unlike skeletal and cardiac muscle tissue, smooth muscle tissue is not striated since there are no sarcomeres present. Skeletal ... Striated muscle tissue has more mitochondria than smooth muscle. Both smooth muscle cells and cardiac muscle cells have a ...
... muscle or connective tissue are intact, a skin graft can be used. A skin graft needs healthy, vascularised tissue beneath it to ... The large blood vessels and nerves of the scalp don't pierce this layer.Loose connective tissue between the periosteum and the ... If this is not possible without tension, the surrounding loose connective tissue can be undermined to attain more mobility. ... Thus, if vascular and nervous anatomy is respected, the skin, subcutaneous tissue and galea aponeurotica can be lifted off the ...
... before any genetic or morphological criteria were put in place for bone marrow or connective tissues. Osteoprogenitor cells can ... These cellular units will then develop into skeletal and other tissues, such as cartilage, tendon, ligament and muscle tissue.[ ... Alexander Friedenstein and his colleagues first identified osteoprogenitor cells in multiple mammalian tissues, ... Tissue Engineering Part A. 14 (9): 1573-80. doi:10.1089/ten.tea.2008.0113. PMID 18774911. Downey, CM; Horton CR; Carlson BA; ...
... is caused by a loss of elasticity in the connective tissue supporting the structure of the front portion of the ... It can also be observed in various hereditary connective tissue disorders, including classical Ehlers-Danlos syndrome and cutis ... In dermatochalasis, the excess tissues hangs down, over the front edge of the eyelid. The excess tissue can sometimes obstruct ... This is observed as the presence of bulges (fat pads) in the soft tissue of the baggy eyes. ...
Secondly, the beef's natural enzymes break down the connective tissue in the muscle, which leads to more tender beef. The ... in order to break down the connective tissue within the meat. Dry-aged beef is beef that has been hung or placed on a rack to ...
"The subepithelial connective tissue pedicle graft combined with the coronally advanced flap for restoring missing papilla: A ... 3. Gingiva biotype; thick and thin tissues often respond differently to inflammation and trauma, thin gingiva is more liable to ...
Intermediate weapons - an amount of force that would have a high probability of causing soft connective tissue damage or bone ... the amount of force that has a probability of causing soft connective tissue damage or bone fractures or irritation of the skin ... a level of force that has a low probability of causing soft connective tissue damage or bone fractures. This would include ...
Large search returns make our pages slow to load. Therefore, some functionality has been disabled until you refine your search to bring the number of returned assay results under TBD ...
There are over 200 disorders that affect connective tissues. Examples include cellulitis, scars, and osteogenesis imperfecta. ... ClinicalTrials.gov: Connective Tissue Diseases (National Institutes of Health) * ClinicalTrials.gov: Mixed Connective Tissue ... Cartilage and fat are types of connective tissue.. Over 200 disorders that impact connective tissue. There are different types: ... Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular ...
Drs Jeffrey Swigris and Sonye Danoff discuss connective tissue disease-related interstitial lung disease (CTD-ILD) to provide ... Connective Tissue Disease-Interstitial Lung Disease. Jeffrey J. Swigris, DO; Sonye K. Danoff, MD, PhD ... Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease: The Pulmonologists Point of View ... Cite this: Connective Tissue Disease-Interstitial Lung Disease - Medscape - Apr 04, 2023. ...
disease and has_disease_location some (connective tissue or part of some connective tissue) ... connective tissue disorder this grouping excludes some diseases affecting tissues classically considered to be connective ... connective tissue disease. Go to external page http://www.ebi.ac.uk/efo/EFO_1001986 Copy ... A disease involving the connective tissue. [ https://orcid.org/0000-0002-6601-2165 ] ...
Mixed connective-tissue disease (MCTD) is a disorder with features of systemic sclerosis (SSc), lupus erythematosus, and ... Dermatologic Manifestations of Mixed Connective Tissue Disease) and Dermatologic Manifestations of Mixed Connective Tissue ... Dermatologic Manifestations of Mixed Connective Tissue Disease * Sections Dermatologic Manifestations of Mixed Connective ... Does mixed connective tissue disease exist? Yes. Rheum Dis Clin North Am. 2005 Aug. 31(3):411-20, v. [QxMD MEDLINE Link]. ...
Connective tissue, a fibrous tissue that encompasses ligaments, tendons, joint capsules and muscle fascia is often plagued by ... CONNECT 2017: International Congress on Connective Tissue. Tendons, Ligaments, Cartilage and Fascia Ulm University 08/26/2019 ... While fascia may be at the forefront of the conference, the intricacies of other connective tissue types - ligaments, tendons, ... The conference will see the coming together of many renowned connective tissue specialists and respected persons from the world ...
When these connective tissues become inflamed, this can harm the proteins and surrounding areas of the body. This is known as a ... Connective tissues hold the structures of the body together. They are made up of two different proteins, collagen and elastin. ... When these connective tissues become inflamed, this can harm the proteins and surrounding areas of the body. This is known as a ... The cause of connective tissue disorders is not always known. Some are caused by a genetic component, while others can be ...
I am prone to writing scenes at the end of works in progress and then filling in connective tissue later, if at all. So far ... Although so far the connective tissues is a lot of talking-about-what-we-are-going-to-do and not many swashes have been buckled ...
Reticular connective tissue - histology slide This is a histology slide of reticular connective tissue. Reticular connective ... tissue forms the framework for most of the lymphoid organs.. Histology slide courtesy of Beatrice Public Schools. ...
Learn about the veterinary topic of Connective Tissue Tumors in Animals. Find specific details on this topic and related topics ... Adipose Tissue Tumors Lipomas are benign tumors of adipose tissue, perhaps more accurately characterized as hamartomas. They ... Fibrosarcomas with abundant interstitial proteoglycans (connective tissue mucins) are called myxosarcomas or myxofibrosarcomas ... Lipomas with an abundant connective tissue stroma (fibrolipomas), cartilaginous stroma (chondrolipomas), or a prominent ...
... trained connective tissue glides easily and is elastic. This helps the body to recover quickly and protects it from injury. ... What is connective tissue? Our connective tissue, also called fascia tissue, consists of an elastic material that runs through ... Strengthen your con-nective tissue: why its worth it & how it works. Strong, trained connective tissue glides easily and is ... What does strong connective tissue achieve?. Strong, trained connective tissue glides easily and is elastic. It protects the ...
... "connective tissue" is.. Connective tissue is one of the four general classes of biological tissues-the others being epithelial ... At PHRC, we refer to the treatment of connective tissue restriction as "connective tissue manipulation." However, the common ... Bones, ligaments, tendons, and cartilage are all considered connective tissue. However, the type of connective tissue that ... muscular, and nervous tissues. The job of connective tissue is to support, connect, or separate different types of tissue and ...
... Food and Nutrition Sciences,06,1522 ... visible connective tissues) were found on M. longissimus thoracis (p = 0.005). On touch, M. longissimus thoracis was considered ... the presence of nerves may be related to connective tissue content (correlation: −0.21) and collagen solubility (correlation: − ... 6. Purslow, P.P. (2005) Intramuscular Connective Tissue and Its Role in Meat Quality. Meat Science, 70, 435-447. http://dx.doi. ...
I had some early symptoms of Marfan Syndrome, a disease that affects connective tissues and can be fatal if there is leakage to ... a connective tissue disorder. The diagnosis was based on physical observations of Lincoln: the fact that he was much taller ... Peter Roe and the tissues are strong, the aortic rout is clear and my heart is in good shape - as long as my Baltimore Ravens ... Actor With Marfans Connective Tissue Disease Actor With Marfans Connective Tissue Disease ...
Neoliberalism as the Connective Tissue of Contemporary Capitalism
Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - Part 1. Posted on ... Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - Part 2 → ... Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - Part 2 → ... 25 responses to "Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - ...
T1 - Ulcerative pyoderma gangrenosum in mixed connective tissue disorder. T2 - A rare association and role of azathioprine in ... Ulcerative pyoderma gangrenosum in mixed connective tissue disorder: A rare association and role of azathioprine in the ... Ulcerative pyoderma gangrenosum in mixed connective tissue disorder: A rare association and role of azathioprine in the ... Ulcerative pyoderma gangrenosum in mixed connective tissue disorder : A rare association and role of azathioprine in the ...
Connective tissue imaged using the CFI Plan Apochromat Lambda D 40XC objective. ... CFI Plan Apochromat Lambda D Series - Connective tissue. Request Information Connective tissue. Connective tissue imaged using ...
Neural tissue. Connective tissue. Along with epithelial tissue, muscle tissue, and nervous tissue, connective tissue is one of ... CBSE NCERT Notes Class 9 Biology Tissues - ExamFear. Class 9 Biology Tissues Connective Tissues CONNECTIVE TISSUES It protects ... Connective Tissues - General Biology. ous connective tissues. As you observe each tissue, look for its special distinguishing ... Notes of Ch 6 Animal Tissues, Class 9th Science. Aug 16, 2017·Connective Tissue. → The cells of the connective tissue are ...
A connective tissue disorder targets the bodys connective tissues, which are the structural materials (mainly the proteins, ... With a connective tissue disease, these proteins are injured by inflammation and can affect the skin, joints, bones, heart, ... Connective tissue disorders that directly affect the skin include the following:. Lupus erythematosus is an autoimmune disease ... Overview: What is a Connective Tissue Disorder? The information in this section has been gathered from existing peer-reviewed ...
tissue res. Outras Variações. 1. Connective tissue research (Online), 1607-8438. 2. Connective tissue research (CD-ROM), 1026- ... Connective tissue research.-- Vol.1 (1972) -.-- London ISSN 0300-8207. Título Abreviado. Connect. ...
Rare Autoimmune/Complex Connective Tissue Diseases ] [ Rare Hereditary Connective Tissue Diseases ] [ Standardization Of Care ... Rare Autoimmune/Complex Connective Tissue Diseases ] [ Rare Hereditary Connective Tissue Diseases ] [ Standardization Of Care ... Rare Autoimmune/Complex Connective Tissue Diseases ] [ Rare Hereditary Connective Tissue Diseases ] [ Standardization Of Care ... Keywords : [ Complex Connective Tissue Diseases ] [ Education ] [ Hta ] [ Knowledge Improvement ] [ Patient Empowerment ] [ ...
It provides structural frame work and gives support to different tissues forming organs. ... It is one of the most abundant and widely distributed tissue. ... i. Connective tissue proper. Connective tissue proper consist ... Fluid connective tissue. The blood and the lymph are the fluid connective tissues which link different parts of the body. The ... Dense Connective Tissue. It is a fibrous connective tissue densely packed with fibres and fibroblasts. It is the principal ...
Connective tissue nevi are hamartomas in which one or several components of the dermis is altered. Lesions in which collagen ... encoded search term (Connective Tissue Nevus) and Connective Tissue Nevus What to Read Next on Medscape ... Connective Tissue Nevus Workup. Updated: Jan 09, 2023 * Author: Steven Brett Sloan, MD; Chief Editor: Dirk M Elston, MD more... ... Fibroblastic connective tissue nevus: a rare cutaneous lesion analyzed in a series of 25 cases. Am J Surg Pathol. 2012 Oct. 36 ...
Duggal L, Bharija SC, Vasdev N. Connective tissue lipoatrophic panniculitis. Journal of the Association of Physicians of India ...
Palavras-chave : subepithelial connective tissue graft; marginal tissue recession; root coverage.. · texto em Inglês · pdf em ... Subepithelial connective tissue graft: a case report. RSBO (Online) [online]. 2011, vol.8, n.3, pp. 357-362. ISSN 1984-5685. ... originating from the connective tissue of both the periosteum and flap. Case report and conclusion: The authors reported a ... show great predictability of total coverage when the technique of subepithelial connective tissue graft is used. This technique ...
Drs Jeffrey Swigris and Sonye Danoff discuss connective tissue disease-related interstitial lung disease (CTD-ILD) to provide ... Connective Tissue Disease-Interstitial Lung Disease. Jeffrey J. Swigris, DO; Sonye K. Danoff, MD, PhD ... Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease: The Pulmonologists Point of View ... Cite this: Connective Tissue Disease-Interstitial Lung Disease - Medscape - Dec 25, 2022. ...
Musculoskeletal and Connective Tissue: Myositis/polymyositis, rhabdomyolysis (and associated sequelae, including renal failure ... Immune-mediated adverse reactions, which may be severe or fatal, can occur in any organ system or tissue, can affect more than ...
Tags Connective cells, Connective Tissue, function of connective tissue, Types of connective tissue 2 Comments. ... Unlike epithelial tissue, connective tissue typically has cells scattered throughout the matrix. Connective tissue is one … ... Types of connective tissue. Connective Tissue , Components, Function, Types. February 10, 2022. February 9, 2022. by Shreya ...
  • Over 200 disorders that impact connective tissue. (medlineplus.gov)
  • Symptoms of connective tissue disorders can vary depending on the affected areas. (cedars-sinai.org)
  • The cause of connective tissue disorders is not always known. (cedars-sinai.org)
  • Because connective tissue disorders can have symptoms similar to other conditions, diagnostic tests will help rule out other causes and confirm a diagnosis. (cedars-sinai.org)
  • There are several disorders that can directly affect the various connective tissues of the body. (factdr.com)
  • This a group of disorders of the connective tissue that arise as a result of defective mutations in the genes. (factdr.com)
  • Consider phospholipidosis as a possible cause of renal injury in patients with underlying connective tissue disorders. (nih.gov)
  • There are over 200 disorders that impact connective tissue. (ezdoctor.com)
  • Injuries can cause connective tissue disorders, such as scars. (ezdoctor.com)
  • Collagen Vascular Lung Disease Collagen vascular or connective tissue disorders are a group of autoimmune diseases in which antibodies attack the body's own organs and systems. (stevefrithphotography.com)
  • Connective tissues diseases (CTDs) are a heterogeneous group of disorders that share certain clinical characteristics and disturbed immunoregulation. (archivesofmedicalscience.com)
  • The rheumatological heritable disorders of connective tissue. (bvsalud.org)
  • Although not fully characterized, the known risk factors for P. jirovecii infection include impaired immunity because of HIV infection, hematologic malignancies, and connective tissue disorders ( 6 ). (cdc.gov)
  • Connective tissue, a fibrous tissue that encompasses ligaments, tendons, joint capsules and muscle fascia is often plagued by injury. (uni-ulm.de)
  • Where is the dense fibrous tissue found? (businessplaners.com)
  • While fascia may be at the forefront of the conference, the intricacies of other connective tissue types - ligaments, tendons, joint capsules and cartilage - will also be appreciated. (uni-ulm.de)
  • Our connective tissue, also called fascia tissue, consists of an elastic material that runs through the entire body and encases organs, tendons, ligaments and muscles. (css.ch)
  • This tissue is found in the dermis, in the fibrous capsule that surrounds the organs, in the sheaths of tendons and nerves, in the periosteum. (businessplaners.com)
  • A daily intake of collagen peptides for the entire body, with a special focus on joints, body tissues, tendons/ligaments and muscles. (fxsupplements.ie)
  • A connective tissue disease is one that affects tissues such as skin, tendons, and cartilage. (nih.gov)
  • Many studies have shown that WBC can improve the circulation in the skin as well as in the connective tissues, tendons, joints, and muscles. (onlinecancerguide.com)
  • A connective tissue disorder targets the body's connective tissues, which are the structural materials (mainly the proteins, collagen and elastin) that hold the cells of the body together. (canadianskin.ca)
  • Scleroderma results from overproduction and accumulation of collagen, a fibrous protein that makes up the connective tissues in the body. (canadianskin.ca)
  • Connective tissue proper consist of collagen bres, elastin bres and broblast cells. (brainkart.com)
  • Put simply, it's collagen acting as connective tissue. (ashleyblackguru.com)
  • By working all of your muscles, bones, and connective tissue in proper alignment, you will rebuild the collagen fibers of your fascia that will give you a bounce in your step. (essentricstv.com)
  • The majority of the body's proteins are composed of collagen, elastin, and other connective tissue components. (drrathresearch.org)
  • Changes of the peri-implant soft tissue thickness after grafting with a collagen matrix. (straumann.com)
  • Vertical soft tissue augmentation with porcine-derived collagen matrix membrane. (straumann.com)
  • Soft tissue volume alterations after connective tissue grafting at teeth: the subepithelial autologous connective tissue graft versus a porcine collagen matrix - a pre-clinical volumetric analysis. (straumann.com)
  • Biodegradation pattern and tissue integration of native and cross-linked porcine collagen soft tissue augmentation matrices - an experimental study in the rat. (straumann.com)
  • according to the National Institutes of Health , it also works as an antioxidant, aids in wound healing and is vital in collagen and connective tissue formation. (nwahomepage.com)
  • Treatments will vary depending on the type of connective tissue disorder diagnosis the patient receives. (cedars-sinai.org)
  • However, the type of connective tissue that we're interested in in the context of pelvic pain is known as "loose connective tissue. (pelvicpainrehab.com)
  • What type of connective tissue firmly inserts muscles to bones? (businessplaners.com)
  • Mixed connective tissue disease (MCTD) is a type of connective tissue regards to clinical and imaging features, it can have significant overlap with other connective tissue diseases such as systemic lupus erythematosus and scleroderma is therefore classified as a type of overlap syndrome and at times it even comes under debate as to whether MCTD should exist as a distinct. (stevefrithphotography.com)
  • Cartilage and fat are types of connective tissue. (medlineplus.gov)
  • 5. Adipose tissue is also known as: fat cartilage Tissues MCQ Class 9 Science Chapter 6 Simple epithelial tissues are generally classified by the shape of their cells. (geertroovers.nl)
  • The supportive tissues include Cartilage and Bone. (brainkart.com)
  • Examples of connective tissues include cartilage, adipose tissue (fat), blood and bone. (factdr.com)
  • It can exist in liquid form (as in the plasma of blood), gelatinous (in areolar tissue), rubbery (in cartilage) or rigid form (as in bone). (factdr.com)
  • His contribution has captivated many in sports medicine, causing them to appreciate the role of fascia - the collagenous tissue found around and between muscles - in muscular injury and pain. (uni-ulm.de)
  • Events include expertly guided workshops on the diagnosis of connective tissue injury via new imaging methods, and fascia-centered coaching on running techniques, rehabilitation and physical therapy. (uni-ulm.de)
  • When in good condition, the fascia tissue around the muscles has a slightly undulating form. (css.ch)
  • When the fascia tissue can no longer fulfil its purpose, we speak of a weakness of the connective tissue. (css.ch)
  • Yet fascia training consists of much more: holistic stretching and mobilisation exercises are an important part of keeping the fascia tissue pliable. (css.ch)
  • This self-massage with either a fascia ball or roller has a similar effect to lymphatic drainage: it squeezes fluid out of the tissue. (css.ch)
  • And contrary to popular belief, your fascia isn't just soft tissue that just surrounds these areas like sausage casing-it is INSIDE them, too. (ashleyblackguru.com)
  • Fascia forms connective tissue, reacts to trauma, acts as a communication system, stores fluid, acts as a delivery system, transfers electrical energy, and functions as long-term storage for compounds both good and bad. (ashleyblackguru.com)
  • While this tightness is a protective measure that prevents you from further injuring yourself, tight fascia tissue can cause problems and limit your range of motion. (ashleyblackguru.com)
  • What is connective tissue/fascia? (bycuram.com)
  • Over the past decade, many anatomical studies have focused on the connective tissues of the human body, specifically the fascia. (seminarsforhealth.ca)
  • Fascia differs as a tissue type and can be quite dense in areas. (seminarsforhealth.ca)
  • Acupuncture causes changes in the fascia, which is the connective tissue that covers your muscles and bones. (cancer.net)
  • The job of connective tissue is to support, connect, or separate different types of tissue and organs. (pelvicpainrehab.com)
  • Connective tissue can become restricted as a result of dysfunction in underlying muscle, nerves, joints and organs. (pelvicpainrehab.com)
  • On top of all of that, it's hypothesized that restricted connective tissue can cause referred pain-including pain to organs (think bladder in the case of pelvic pain)- via the central nervous system. (pelvicpainrehab.com)
  • Semantics aside, to fully treat connective tissue restriction, a PT has to normalize its mobility, improve circulation to the area, reduce hypersensitivity, and minimize the negative reflexive effects on surrounding muscles, nerves, and organs. (pelvicpainrehab.com)
  • 3. Reticular fibers -provide a network to support blood vessels and support soft tissue of organs.Tissues Class 9 Notes - Chapter 6 Important Points To KnowCBSE Class 9 Science Notes on Tissues. (geertroovers.nl)
  • It provides structural frame work and gives support to different tissues forming organs. (brainkart.com)
  • The main function of the connective tissue is binding, supporting and packing together different organs of the body. (brainkart.com)
  • They are found in subcutaneous tissue, between internal organs around the heart and kidneys. (brainkart.com)
  • Bones support and protect soft tissues and organs. (brainkart.com)
  • The role of connective tissue, as the name suggests, is to bind, support and connect other tissues and organs together. (factdr.com)
  • These three components come together to form the glue that provides the extracellular matrix for other tissues and organs. (factdr.com)
  • Since connective tissues form the structural framework within our bodies, diseases affecting them will also have an impact on organs and other tissues associated with them. (factdr.com)
  • Other symptoms of Carney complex depend on the location of tumors, their size, and how the tumors affect the function of body organs and tissues. (nih.gov)
  • Marfan syndrome is a genetic disorder that affects the body's ability to make healthy connective tissue, which supports the bones, muscles, organs, and tissues in your body. (nih.gov)
  • Organs and tissues exposed to the external environment such as the gut have the highest density of mast cells. (hackyourgut.com)
  • This is an obstetrician-gynecologist with additional training in problems that affect the pelvic floor - the network of muscles, ligaments, connective tissue and nerves that helps support and control the bladder and other pelvic organs. (drugs.com)
  • Sixteen consecutive patients with connective tissue diseases were included in the study. (cdriadvlkn.org)
  • Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. (stevefrithphotography.com)
  • The growth plate is the area of tissue near the ends of long bones in children and teens that determines what length and shape the bone will be once it is done growing. (nih.gov)
  • Minerals and vitamins are important for the development and maintenance of bones and tissues, the production of milk in mares, and the regulation of basic body functions. (bestfriendequine.com)
  • Strengthening the joints, spine and building strong bones, while helping to form connective tissue. (hempusa.org)
  • Example questions to be discussed around include: What specific processes are in action during inflammatory processes in muscular connective tissues? (uni-ulm.de)
  • Connective tissue is one of the four general classes of biological tissues-the others being epithelial, muscular, and nervous tissues. (pelvicpainrehab.com)
  • Muscular tissue. (geertroovers.nl)
  • The four main types are epithelial, muscular, connective and nervous tissues. (factdr.com)
  • A pleasant, strong pressure and a deep, stroking massage stretches and opens the connective tissue, releasing deep-seated muscular tension and myogelosis. (thegeorge-hotel.de)
  • Epithelial tissue. (geertroovers.nl)
  • Along with epithelial tissue, muscle tissue, and nervous tissue, connective tissue is one of the four essential forms of animal tissue. (geertroovers.nl)
  • The tissue which has minimum intercellular space is epithelial tissue and connective tissue has largest intercellular spaces. (geertroovers.nl)
  • The epithelial tissue has great regeneration power and it is the first evolved tissue. (geertroovers.nl)
  • Unlike epithelial tissue, connective tissue typically has cells scattered throughout the matrix. (edu-mate.com)
  • Overlapping criteria for diagnosis of mixed connective tissue disease (MCTD) have been published by Sharp, Alarcón-Segovia, Kasukawa, and Kahn. (medscape.com)
  • 2019 Diagnostic criteria for mixed connective tissue disease (MCTD): From the Japan research committee of the ministry of health, labor, and welfare for systemic autoimmune diseases. (medscape.com)
  • We described a 69-year-old woman with neurological manifestations due to mixed connective tissue disease (MCTD). (who.int)
  • In just 30 minutes you'll dispel any feelings of stiffness or "locked down" muscles and connective tissue. (essentricstv.com)
  • In contrast, many Western practitioners view the acupuncture points as places to stimulate nerves, muscles and connective tissue. (boonechamber.com)
  • Marfan syndrome an inherited disorder of connective tissue occurring once in every 10,000 to 20,000 individuals. (genome.gov)
  • This is known as a connective tissue disorder. (cedars-sinai.org)
  • Exposed root surfaces can be treated with a gum grafting procedure, also known as a connective tissue graft, at the affected site. (blackbeagledds.com)
  • Adipose tissue is the aggregation of fat cells or adipocytes and serves as fat reservoir. (brainkart.com)
  • Connective tissues are classified on the basis of the chemical-physical nature of the intercellular matrix that compose them: … Together with the adipose tissue, it forms the subcutaneous layer. (businessplaners.com)
  • It is a fluid connective tissue which is composed of the matrix called P lasma and formed elements . (aakash.ac.in)
  • In this fluid connective tissue, the blood cells move in a fluid matrix called plasma. (brainkart.com)
  • Loose connective tissue is aptly named because its fibers are randomly arranged and there's lots of space between the cells, which makes it THE ideal tissue for cushioning and protecting. (pelvicpainrehab.com)
  • Fibers of connective tissue: 1. (geertroovers.nl)
  • Fascial fibers form a thin casing of protective tissue that surrounds every system in your body. (ashleyblackguru.com)
  • Loose connective tissue is characterized by the presence of numerous cells with variable typology and by an amorphous substance poor in fibers and not particularly dense, therefore not very dyeable with normal histological stains. (businessplaners.com)
  • In the spirit of preventing and managing such occurrences, professional trainers, physiotherapists, sport physicians and physiologists are coming together at the CONNECT 2017 - CONNECTIVE TISSUES IN SPORTS MEDICINE conference. (uni-ulm.de)
  • Aug 16, 2017·Connective Tissue. (geertroovers.nl)
  • The aim of the ERN-RECONNET's annual work plan for 2017 is to establish a community to enhance transnational cooperation between different groups (healthcare providers, patients, caregivers and families, stakeholders, etc.) to develop a comprehensive and harmonized approach to rare and complex autoimmune and hereditary connective and musculoskeletal diseases (rCTDs). (europa.eu)
  • Besides surrounding blood vessels and nerves, one of the biggest jobs of loose connective tissue in the body is to attach the skin to the muscles. (pelvicpainrehab.com)
  • 4] Thenceforth, nailfold capillaroscopy become an important diagnostic tool for diagnosing progressive connective tissue diseases such as systemic sclerosis, mixed connective tissue disease, lupus erythematosus, dermatomyositis, and polymyositis, and also in patients with Raynaud's phenomenon. (cdriadvlkn.org)
  • Myxomas are noncancerous growths of the body's connective tissue, including skin and muscle. (nih.gov)
  • Miller's Classes I and II recessions, in which the etiological factors are well diagnosed and eliminated, show great predictability of total coverage when the technique of subepithelial connective tissue graft is used. (bvsalud.org)
  • Case report and conclusion: The authors reported a clinical case in which a Miller's Class I recession was treated by the surgical technique of subepithelial connective tissue graft, obtaining total coverage, eliminating the aesthetic deficiency and the dentin hypersensitivity complained by patient. (bvsalud.org)
  • Treatment of Gingival Recession Defects with Pouch and Tunnel Technique Using Connective Tissue Graft and L. (medscimonit.com)
  • The versatile subepithelial connective tissue graft: a literature update. (bvsalud.org)
  • Among a multitude of surgical techniques and graft materials reported in literature , the subepithelial connective tissue graft (SCTG) has gained wide popularity and acceptance. (bvsalud.org)
  • 7] In this article, authors have studied the precision of a dermoscope as a capillaroscopy in evaluating nailfold capillaries in various connective tissue diseases in the skin of color. (cdriadvlkn.org)
  • There can be difficulties relating to the muscles, skin, and joints as a result of connective tissue disease (CTD). (factdr.com)
  • Plus, research shows that connective tissue restrictions lead to local pain via the peripheral nervous system. (pelvicpainrehab.com)
  • Tissues are broadly classified in four types- epithelium connective tissue smooth muscle tissue nervous tissue In this article we are going to study about connective tissues. (gpatindia.com)
  • Pulmonary arterial hypertension (PAH) is a common and fatal complication of connective tissue diseases (CTDs). (stevefrithphotography.com)
  • Typically, connective tissues consist of a far higher proportion of non-living substance than living cells. (factdr.com)
  • Connective tissue consist of two basic elements, the extracellular matrix and the cells. (gpatindia.com)
  • Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. (medlineplus.gov)
  • Skin rolling" or "connective tissue manipulation" as I'll be referring to it throughout this post, is a major component of our pelvic pain treatment technique here at PHRC. (pelvicpainrehab.com)
  • When the connective tissue that attaches the skin to the muscle becomes restricted (think thickened or dense) it can and does cause pain. (pelvicpainrehab.com)
  • When a PT carries out a pinch-roll test he or she will roll a fold of skin between his or her fingers, and note whether the tissue is thickened. (pelvicpainrehab.com)
  • However, the common term used to describe connective tissue manipulation is "skin rolling. (pelvicpainrehab.com)
  • After all, it's the connective tissue, not the skin that's being taken to task. (pelvicpainrehab.com)
  • It also helps in repair of tissues after injury and fixes skin to underlying muscles. (brainkart.com)
  • Authors evaluated the utility of dermoscopy in the study of nailfold capillaries in connective tissue diseases in patient with the skin of color. (cdriadvlkn.org)
  • The skin is connected by strands of fibrous tissues to deeper tissue layers, which separates the fat cell compartments. (queenbeeing.com)
  • Scleroderma is an autoimmune connective tissue and rheumatic disease that causes inflammation in the skin and other areas of the body. (nih.gov)
  • UVA is believed to damage connective tissue and increase the risk for developing skin cancer. (cdc.gov)
  • West Nile Virus transmission through tissue transplantation, for instance, skin, muscle, or connective tissues, has not been identified, and the risk for transmission by this route is not known. (cdc.gov)
  • Eight weeks after the donor's death, skin samples that had been treated in cryopreservative solution containing an antibiotic and unprocessed fat, muscle, tendon, and bone samples, all of which had been stored frozen at -70° Celsius at a tissue bank, were transferred to CDC. (cdc.gov)
  • D21.3 is a valid billable ICD-10 diagnosis code for Benign neoplasm of connective and other soft tissue of thorax . (icd10coded.com)
  • Harmony between hard and soft tissue morphologies is essential for form, function, and a good esthetic outlook. (bvsalud.org)
  • Replacement grafts for correction of soft tissue defects around the teeth have become important to periodontal plastic and implant surgical procedures . (bvsalud.org)
  • The Use of a Novel Porcine Derived Acellular Dermal Matrix (mucoderm®) in Peri-Implant Soft Tissue Augmentation: Preliminary Results of a Prospective Pilot Cohort Study. (straumann.com)
  • Hernia mesh products are designed to repair hernias and other defects by reinforcing the surrounding soft tissue. (meshbesher.com)
  • Mixed connective tissue disease--an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). (medscape.com)
  • The objective of the ERN ReCONNET's annual work plan for 2018 is to go on in the work already started during the first year, aimed at improving a community to enhance transnational cooperation between different groups to develop a comprehensive and harmonized approach to rare and complex autoimmune and hereditary connective and musculoskeletal diseases (rCTDs). (europa.eu)
  • The connective tissues are made up of cells of various shapes, not in direct contact with each other, but dispersed in an abundant extracellular matrix. (businessplaners.com)
  • Which connective tissue cell is responsible for the synthesis of the extracellular matrix? (businessplaners.com)
  • In both organ systems, these processes involve to a great extent the connective tissues, in particular the manner in which the extracellular materials are arranged to afford such movements. (stevefrithphotography.com)
  • More specifically, the inflammation associated with connective tissue will be explored. (uni-ulm.de)
  • Cerebrospinal Meningitis is an inflammation of the thin layer of connective tissue that covers the brain and the spinal cord. (who.int)
  • Introduction to Tissues Tissues Tissues are a group of cells that combine together to perform a particular function. (geertroovers.nl)
  • Tissue refers to a group of cells with intracellular components to perform a particular function. (geertroovers.nl)
  • The cells of the connective tissue are widely spaced and embedded in an intercellular matrix. (geertroovers.nl)
  • The components of the connective tissue are the intercellular substance known as the matrix, connective tissue cells and fibres. (brainkart.com)
  • A bio-ceramic additive reflects your body's own infrared rays, which help to break down cellulite cells and revitalize tissue. (queenbeeing.com)
  • Sometimes, and often for unknown reasons, the immune system turns on the healthy cells and tissues of the body, causing them to become inflamed and damaged. (factdr.com)
  • The most striking and characteristic histologic feature of the verruciform xanthoma is the presence of large foam cells in the connective-tissue papillae. (medscape.com)
  • Co-staining for proSPC and IL-1beta showed that while both exposures increased IL-beta+ cells in lung tissue, CNTinduced IL-1beta increases were largely specific to T2Ps. (cdc.gov)
  • Mast cells are immune cells found in connective tissues in your body. (hackyourgut.com)
  • Twenty-four 1-d-old broilers were distributed in 2 groups, pulmonary hypertensive broilers (PHB) and pulmonary nonhypertensive broilers (NPHB), to estimate possible differences between them in the expression of endothelin 1 (ET-1) and its type A receptor, connective tissue growth factor, platelet-derived growth factor, and adrenomedullin expression in the lungs. (eurekamag.com)
  • Connective tissue growth factor mRNA levels in the lungs of PHB were significantly higher than in the lungs of NPHB (P (eurekamag.com)
  • It has been demonstrated for the first time that ET-1, connective tissue growth factor, and adrenomedullin are upregulated in the lungs of PHB. (eurekamag.com)
  • This book concerns the microenvironment of the connective tissues in the walls of arteries and the stroma of lungs. (stevefrithphotography.com)
  • The EOMs exhibit a distinct 2-layer organization: an outer orbital layer, which acts only on connective tissue pulleys (see the section The Pulley System, later in the chapter), and an inner global layer, whose tendon inserts on the sclera to move the globe (Fig 3-4). (aao.org)
  • Yoshida S. Pulmonary arterial hypertension in connective tissue diseases. (medscape.com)
  • 3 edition of Connective tissues in arterial and pulmonary disease found in the catalog. (stevefrithphotography.com)
  • Pulmonary arterial hypertension is the most common disease-related cause of death in patients with mixed connective tissue disease. (stevefrithphotography.com)
  • Pulmonary Manifestations of Connective Tissue Diseases toms, consistent PFTs and typical radiological find-ings. (stevefrithphotography.com)
  • By expert consensus, PAH is diagnosed when at right heart catheterisation a mean pulmonary Connective tissues in arterial and pulmonary disease book pressure (PAP) >25mmHg at rest or >30mmHg during exercise is measured, together with a normal wedge pressure and a normal or reduced cardiac output. (stevefrithphotography.com)
  • Most obvious among these connective functions, various social assets are built and/or maintained by government that form physical connections between the components of the society and enable people to physically interact with each other and come into possession of or experience goods and services they desire. (neweconomicperspectives.org)
  • On a fundamental level, all connective tissue is composed of more or less the same mix of components. (factdr.com)
  • IMSEAR at SEARO: Encephalopathy and severe neuropathy due to probable systemic vasculitis as an initial manifestation of mixed connective tissue disease. (who.int)
  • Matsui H, Udaka F, Oda M, Kubori T, Nishinaka K, Kameyama M. Encephalopathy and severe neuropathy due to probable systemic vasculitis as an initial manifestation of mixed connective tissue disease. (who.int)
  • Connective tissues hold the structures of the body together. (cedars-sinai.org)
  • When these connective tissues become inflamed, this can harm the proteins and surrounding areas of the body. (cedars-sinai.org)
  • When the body is subject to unaccustomed strains - as in a fall, for example - elastic, stable tissue will help prevent injury. (css.ch)
  • Connective Tissues These tissues help in connecting different parts of the body. (geertroovers.nl)
  • The most abundant tissue in animal body is the connective tissue. (geertroovers.nl)
  • It is a specialised connective tissue in the body. (aakash.ac.in)
  • The supporting or skeletal connective tissues forms the endoskeleton of the vertebrate body. (brainkart.com)
  • The blood and the lymph are the fluid connective tissues which link different parts of the body. (brainkart.com)
  • Connective tissue is the master connecting organ of your body - integrating movement, the brain, circulation, immune function, and emotional expression. (askdrlavine.com)
  • Craniosacral therapy is the gentlest form of body work that releases restriction of the connective tissues. (askdrlavine.com)
  • There are several types of tissue in the human body and each kind has a specified function. (factdr.com)
  • It is the most abundant form of tissue in the body and can take many different forms. (factdr.com)
  • Connective tissue is the material inside your body that supports many of its parts. (ezdoctor.com)
  • Treating the body this way can benefit massage clients who have plateaued with the use of massage treatments directed at non-fascial tissues. (seminarsforhealth.ca)
  • As of my last scans in December 2010, my lung lesion is only scarred tissue, the spine and lymph nodes are not visible, and the brain lesions are 60% reduced. (burzynskipatientgroup.org)
  • Inject intact proteins from peanuts, eggs and dairy (casein) products directly into the infantʼs muscle tissue 36 times before the age of 18 months. (yogaesoteric.net)
  • During aging, enzymes naturally present in the meat break down muscle proteins and connective tissues, while moisture evaporating from meat concentrates flavor. (outdoorlife.com)
  • Following clinical usage of the term 'connective tissue disorder' this grouping excludes some diseases affecting tissues classically considered to be connective tissue, such as bone. (ebi.ac.uk)
  • Patients who present with thin tissue, prominent teeth, aggressive tooth brushing habits, or thin bone may be subject to the exposure of root surfaces. (blackbeagledds.com)
  • It is a fibrous connective tissue densely packed with fibres and fibroblasts. (brainkart.com)
  • This layer of dense, fibrous connective tissue surrounds individual muscles and ligaments and groups them together for functional movement. (ashleyblackguru.com)
  • Where Is Dense Fibrous Connective Tissue Absent? (businessplaners.com)
  • Where is the irregular dense connective tissue found? (businessplaners.com)
  • Amigues JM, Cantagrel A, Abbal M, Mazieres B. Comparative study of 4 diagnosis criteria sets for mixed connective tissue disease in patients with anti-RNP antibodies. (medscape.com)
  • However, within specific populations such as at risk groups (e.g., patients with connective tissue disease), we urge increased awareness and adherence to consensus guidelines in terms of screening and diagnosis. (renalandurologynews.com)
  • Ground substance performs the role of a medium facilitating the exchange of substances between the blood and various tissues. (factdr.com)
  • Fibrillin is a substance that imparts strength to connective tissue. (factdr.com)
  • The fundamental substance, also called amorphous substance, is an acellular component of the connective tissue. (businessplaners.com)
  • Absorbable mesh is typically made of animal tissue that has been processed for medical use. (meshbesher.com)
  • This technique success has been mainly attributed to the double blood supply for graft's nutrition, originating from the connective tissue of both the periosteum and flap. (bvsalud.org)