Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.
A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.
A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.
A group of cells that includes FIBROBLASTS, cartilage cells, ADIPOCYTES, smooth muscle cells, and bone cells.
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue.
Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)
Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.
A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
A CCN protein family member found at high levels in NEPHROBLASTOMA cells. It is found both intracellularly and in the EXTRACELLULAR MATRIX and may play a role in the regulation of CELL PROLIFERATION and EXTRACELLULAR MATRIX synthesis.
A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.
Exposure of the root surface when the edge of the gum (GINGIVA) moves apically away from the crown of the tooth. This is common with advancing age, vigorous tooth brushing, diseases, or tissue loss of the gingiva, the PERIODONTAL LIGAMENT and the supporting bone (ALVEOLAR PROCESS).
Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.
Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state.
Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.
Surgical reshaping of the gingivae and papillae for correction of deformities (particularly enlargements) and to provide the gingivae with a normal and functional form, the incision creating an external bevel. (Dorland, 28th ed)
Oral tissue surrounding and attached to TEETH.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Bony cavity that holds the eyeball and its associated tissues and appendages.
Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).
Signal molecules that are involved in the control of cell growth and differentiation.
An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.
Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Classical loci in ACUPUNCTURE. They are main and collateral channels, regarded as a network of passages, through which vital energy (Qi) circulates and along which acupoints (ACUPUNCTURE POINTS) are distributed. The meridians are a series of 14 lines upon which more than 400 acupoints are located on the body. (The Pinyin Chinese-English Dictionary, p. 359; Dr. Wu Lancheng, Academy of Traditional Chinese Medicine, Beijing)
A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
A fibrillar collagen consisting of three identical alpha1(III) chains that is widely distributed in many tissues containing COLLAGEN TYPE I. It is particularly abundant in BLOOD VESSELS and may play a role in tissues with elastic characteristics.
A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It may play an important role in the development of branched CAPILLARIES during EMBRYOGENESIS.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A wedge-shaped collar of epithelial cells which form the attachment of the gingiva to the tooth surface at the base of the gingival crevice.
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
A family of structurally related collagens that form the characteristic collagen fibril bundles seen in CONNECTIVE TISSUE.
Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris.
A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.
A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.
Restoration of integrity to traumatized tissue.
A genus of large SEA CUCUMBERS in the family Holothuriidae possessing thick body walls, a warty body surface, and microscopic ossicles.
Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.
Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
Glycoproteins which have a very high polysaccharide content.
Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
Components of the extracellular matrix consisting primarily of fibrillin. They are essential for the integrity of elastic fibers.
A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.
A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
Layers of connective tissue of variable thickness. The superficial fascia is found immediately below the skin; the deep fascia invests MUSCLES, nerves, and other organs.
Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.
A collective term for diseases of the skin and its appendages and of connective tissue.
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.
A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
A genus of very large, epibenthic SEA CUCUMBERS in the family Stichopodidae, commercially harvested in Southeast Asia for food.
Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
Elements of limited time intervals, contributing to particular results or situations.
Monomeric subunits of primarily globular ACTIN and found in the cytoplasmic matrix of almost all cells. They are often associated with microtubules and may play a role in cytoskeletal function and/or mediate movement of the cell or the organelles within the cell.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Any of certain small mammals of the order Hyracoidea.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
The protein components that constitute the common core of small nuclear ribonucleoprotein particles. These proteins are commonly referred as Sm nuclear antigens due to their antigenic nature.
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
A biosynthetic precursor of collagen containing additional amino acid sequences at the amino-terminal and carboxyl-terminal ends of the polypeptide chains.
The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.
The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).
Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN TYPE I and COLLAGEN TYPE III. It is a heterotrimeric molecule composed of alpha1(V), alpha2(V) and alpha3(V) subunits. Several forms of collagen type V exist depending upon the composition of the subunits that form the trimer.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Enzymes that catalyze the degradation of collagen by acting on the peptide bonds.
A class of Echinodermata characterized by long, slender bodies.
A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.
The anteriorly located rigid section of the PALATE.
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and often re-expressed in tumors. It is present in the central and peripheral nervous systems as well as in smooth muscle and tendons. (From Kreis & Vale, Guidebook to the Extracellular Matrix and Adhesion Proteins, 1993, p93)
Inflammation of a muscle or muscle tissue.
A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Fleshy and reddish outgrowth of skin tissue found on top of the head, attached to the sides of the head, and hanging from the mandible of birds such as turkeys and chickens.
Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
The region corresponding to the human WRIST in non-human ANIMALS.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.
A scleroprotein fibril consisting mostly of type III collagen. Reticulin fibrils are extremely thin, with a diameter of between 0.5 and 2 um. They are involved in maintaining the structural integrity in a variety of organs.
Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
A small leucine-rich proteoglycan found in a variety of tissues including CAPILLARY ENDOTHELIUM; SKELETAL MUSCLE; CARTILAGE; BONE; and TENDONS. The protein contains two glycosaminoglycan chains and is similar in structure to DECORIN.
Generalized or localized diffuse fibrous overgrowth of the gingival tissue, usually transmitted as an autosomal dominant trait, but some cases are idiopathic and others produced by drugs. The enlarged gingiva is pink, firm, and has a leather-like consistency with a minutely pebbled surface and in severe cases the teeth are almost completely covered and the enlargement projects into the oral vestibule. (Dorland, 28th ed)
Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
ENDOPEPTIDASES which use a metal such as ZINC in the catalytic mechanism.
A phylum of the most familiar marine invertebrates. Its class Stelleroidea contains two subclasses, the Asteroidea (the STARFISH or sea stars) and the Ophiuroidea (the brittle stars, also called basket stars and serpent stars). There are 1500 described species of STARFISH found throughout the world. The second class, Echinoidea, contains about 950 species of SEA URCHINS, heart urchins, and sand dollars. A third class, Holothuroidea, comprises about 900 echinoderms known as SEA CUCUMBERS. Echinoderms are used extensively in biological research. (From Barnes, Invertebrate Zoology, 5th ed, pp773-826)
A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.
The minute vessels that connect the arterioles and venules.
Contractile tissue that produces movement in animals.
The process of bone formation. Histogenesis of bone including ossification.
The farthest or outermost projections of the body, such as the HAND and FOOT.
Resistance and recovery from distortion of shape.
The occupational discipline of the traditional Chinese methods of ACUPUNCTURE THERAPY for treating disease by inserting needles along specific pathways or meridians.
COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I.
Fibroblasts which occur in the CORNEAL STROMA.
Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
A salt-soluble precursor of elastin. Lysyl oxidase is instrumental in converting it to elastin in connective tissue.
The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
The middle germ layer of an embryo derived from three paired mesenchymal aggregates along the neural tube.
A mucopolysaccharide constituent of chondrin. (Grant & Hackh's Chemical Dictionary, 5th ed)
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.
The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
An enzyme oxidizing peptidyl-lysyl-peptide in the presence of water & molecular oxygen to yield peptidyl-allysyl-peptide plus ammonia & hydrogen peroxide. EC
A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.
The application of knowledge to the food industry.
Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)
An extracellular endopeptidase of vertebrate tissues similar to MATRIX METALLOPROTEINASE 1. It digests PROTEOGLYCAN; FIBRONECTIN; COLLAGEN types III, IV, V, and IX, and activates procollagenase. (Enzyme Nomenclature, 1992)
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
Proteins prepared by recombinant DNA technology.
High molecular weight insoluble polymers which contain functional anionic groups that are capable of undergoing exchange reactions with cations.
The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)
Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.
A non-fibrillar collagen that forms a network of MICROFIBRILS within the EXTRACELLULAR MATRIX of CONNECTIVE TISSUE. The alpha subunits of collagen type VI assemble into antiparallel, overlapping dimers which then align to form tetramers.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Methods of preparing tissue for examination and study of the origin, structure, function, or pathology.
Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.
The least progressive form of SYSTEMIC SCLERODERMA with skin thickening restricted to the face, neck and areas distal to the elbows and/or knees, sparing the trunk. The CREST SYNDROME is a form of limited scleroderma.
High molecular weight, insoluble polymers which contain functional groups that are capable of undergoing exchange reactions (ION EXCHANGE) with either cations or anions.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.
A sulfated mucopolysaccharide initially isolated from bovine cornea. At least two types are known. Type I, found mostly in the cornea, contains D-galactose and D-glucosamine-6-O-sulfate as the repeating unit; type II, found in skeletal tissues, contains D-galactose and D-galactosamine-6-O-sulfate as the repeating unit.
Chronic inflammation and granuloma formation around irritating foreign bodies.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.
A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
The restriction of the MOVEMENT of whole or part of the body by physical means (RESTRAINT, PHYSICAL) or chemically by ANALGESIA, or the use of TRANQUILIZING AGENTS or NEUROMUSCULAR NONDEPOLARIZING AGENTS. It includes experimental protocols used to evaluate the physiologic effects of immobility.
Established cell cultures that have the potential to propagate indefinitely.
Proteoglycans consisting of proteins linked to one or more CHONDROITIN SULFATE-containing oligosaccharide chains.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)
An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS.
A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. It regulates TRANSFORMING GROWTH FACTOR BETA and ACTIVIN signaling.
A fibrous cord that connects the muscles in the back of the calf to the HEEL BONE.
A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
A disease characterized by bony deposits or the ossification of muscle tissue.
The part of the membranous labyrinth that traverses the bony vestibular aqueduct and emerges through the bone of posterior cranial fossa (CRANIAL FOSSA, POSTERIOR) where it expands into a blind pouch called the endolymphatic sac.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
A porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates to the canal of Schlemm.
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
A member of the metalloproteinase family of enzymes that is principally responsible for cleaving FIBRILLAR COLLAGEN. It can degrade interstitial collagens, types I, II and III.
The physiological renewal, repair, or replacement of tissue.
The forces and principles of action of matter and energy.
A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (From Dorland, 27th ed)

Destruction of hyaline cartilage in the sigmoid notch of the human ulna. (1/1596)

In an ulna from an adolescent a fossa nudata divided the articular surface of the sigmoid notch into olecranon and coronoid areas. In the floor of the fossa a layer of loose avascular pannus covered a thin layer of articular cartilage. The pannus appeared to have been formed by removal of chondroitin from the cartilage, freeing the cells and unmasking the fibres. Probably the change followed loss of contact between the articular cartilages of the sigmoid notch and trochlea during postnatal growth.  (+info)

Structural changes in intramuscular connective tissue during the fattening of Japanese black cattle: effect of marbling on beef tenderization. (2/1596)

We investigated changes in structures and mechanical properties of the intramuscular connective tissue during the fattening of Japanese Black steers, using the cell maceration method for scanning electron microscopy. During the early fattening period, from 9 to 20 mo of age, collagen fibrils of the endomysium in longissimus muscle associated more closely with each other, and collagen fibers in the perimysium increased in thickness and their wavy pattern became more regular. These changes were closely related to the increase in mechanical strength of the intramuscular connective tissue and resulted in a toughening of the beef during the period. The shear force value of longissimus muscle decreased after 20 mo of age, concomitantly with the rapid increase in the crude fat content. Scanning electron micrographs of the longissimus muscle dissected from 32-mo-old steers clearly showed that the adipose tissues were formed between muscle fiber bundles, that the honeycomb structure of endomysia was partially broken, and that the perimysium separated into thinner collagen fibers. In semitendinosus muscle, in which the crude fat content was lower (P<.05) than that in longissimus muscle, the structure of the intramuscular connective tissue remained rigid at 32 mo of age. The shear force value of the muscle increased even in the late fattening period, from 20 to 32 mo of age. Thus, the development of adipose tissues in longissimus muscle appears to disorganize the structure of the intramuscular connective tissue and contributes to tenderization of highly marbled beef from Japanese Black cattle during the late fattening period.  (+info)

Relationship between development of intramuscular connective tissue and toughness of pork during growth of pigs. (3/1596)

We investigated changes in structures and properties of the endomysium and perimysium during development of semitendinosus muscle in relation to the increase in toughness of pork using samples from neonates to 55-mo-old pigs. The shear force value of pork increased linearly until 6 mo of age, and the rate of increase slowed down thereafter. The secondary perimysium thickened owing to an increase in the number and thickness of perimysial sheets consisting of collagen fibers, which became thicker and wavy with the growth of the pigs. This increase in thickness of the secondary perimysium was correlated significantly with the increase in the shear force value (r = .98). The endomysial sheaths became thicker and denser in the muscle of 6-mo-old pigs. Maturation of the endomysium was accompanied by hypertrophy of muscle fibers. The amount of heat-soluble collagen decreased almost linearly, indicating that nonreducible cross-links between collagen molecules were formed throughout chronological aging. We conclude that thickening of the perimysium is closely related to an increase in the toughness of pork during growth of pigs.  (+info)

Interaction of Borrelia burgdorferi with peripheral blood fibrocytes, antigen-presenting cells with the potential for connective tissue targeting. (4/1596)

BACKGROUND: Borrelia Burgdorferi has a predilection for collagenous tissue and can interact with fibronectin and cellular collagens. While the molecular mechanisms of how B. burgdorferi targets connective tissues and causes arthritis are not understood, the spirochetes can bind to a number of different cell types, including fibroblasts. A novel circulating fibroblast-like cell called the peripheral blood fibrocyte has recently been described. Fibrocytes express collagen types I and III as well as fibronectin. Besides playing a role in wound healing, fibrocytes have the potential to target to connective tissue and the functional capacity to recruit, activate, and present antigen to CD4(+) T cells. MATERIALS AND METHODS: Rhesus monkey fibrocytes were isolated and characterized by flow cytometry. B. burgdorferi were incubated with human or monkey fibrocyte cultures in vitro and the cellular interactions analyzed by light and electron microscopy. The two strains of B. burgdorferi studied included JD1, which is highly pathogenic for monkeys, and M297, which lacks the cell surface OspA and OspB proteins. RESULTS: In this study, we demonstrate that B. burgdorferi binds to both human and monkey (rhesus) fibrocytes in vitro. This process does not require OspA or OspB. In addition, the spirochetes are not phagocytosed but are taken into deep recesses of the cell membrane, a process that may protect them from the immune system. CONCLUSIONS: This interaction between B. burgdorferi and peripheral blood fibrocytes provides a potential explanation for the targeting of spirochetes to joint connective tissue and may contribute to the inflammatory process in Lyme arthritis.  (+info)

Connective tissues: matrix composition and its relevance to physical therapy. (5/1596)

In the last 2 decades, the understanding of CT structure and function has increased enormously. It is now clear that the cells of the various CTs synthesize a variety of ECM components that act not only to underpin the specific biomechanical and functional properties of tissues, but also to regulate a variety of cellular functions. Importantly for the physical therapist, and as discussed above, CTs are responsive to changes in the mechanical environment, both naturally occurring and applied. The relative proportions of collagens and PGs largely determine the mechanical properties of CTs. The relationship between the fibril-forming collagens and PG concentration is reciprocal. Connective tissues designed to resist high tensile forces are high in collagen and low in total PG content (mostly dermatan sulphate PGs), whereas CTs subjected to compressive forces have a greater PG content (mostly chondroitin sulphate PGs). Hyaluronan has multiple roles and not only provides tissue hydration and facilitation of gliding and sliding movements but also forms an integral component of large PG aggregates in pressure-resisting tissues. The smaller glycoproteins help to stabilize and link collagens and PGs to the cell surface. The result is a complex interacting network of matrix molecules, which determines both the mechanical properties and the metabolic responses of tissues. Patients with CT problems affecting movement are frequently examined and treated by physical therapists. A knowledge of the CT matrix composition and its relationship to the biomechanical properties of these tissues, particularly the predictable responses to changing mechanical forces, offers an opportunity to provide a rational basis for treatments. The complexity of the interplay among the components, however, requires that further research be undertaken to determine more precisely the effects of treatments on the structure and function of CTs.  (+info)

Recombinant human type II collagens with low and high levels of hydroxylysine and its glycosylated forms show marked differences in fibrillogenesis in vitro. (6/1596)

Type II collagen is the main structural component of hyaline cartilages where it forms networks of thin fibrils that differ in morphology from the much thicker fibrils of type I collagen. We studied here in vitro the formation of fibrils of pepsin-treated recombinant human type II collagen produced in insect cells. Two kinds of type II collagen preparation were used: low hydroxylysine collagen having 2.0 hydroxylysine residues/1,000 amino acids, including 1.3 glycosylated hydroxylysines; and high hydroxylysine collagen having 19 hydroxylysines/1,000 amino acids, including 8.9 glycosylated hydroxylysines. A marked difference in fibril formation was found between these two kinds of collagen preparation, in that the maximal turbidity of the former was reached within 5 min under the standard assay conditions, whereas the absorbance of the latter increased until about 600 min. The critical concentration with the latter was about 10-fold, and the absorbance/microgram collagen incorporated into the fibrils was about one-sixth. The morphology of the fibrils was also different, in that the high hydroxylysine collagen formed thin fibrils with essentially no interfibril interaction or aggregation, whereas the low hydroxylysine collagen formed thick fibrils on a background of thin ones. The data thus indicate that regulation of the extents of lysine hydroxylation and hydroxylysine glycosylation may play a major role in the regulation of collagen fibril formation and the morphology of the fibrils.  (+info)

Altered connective tissue in children with congenital dislocation of the hip. (7/1596)

The umbilical cord was employed as a source of collagen in 10 children with congenital dislocation of hip. The amount of collagen and its solubility were measured in slices of the cords and in the umbilical veins and compared with the values in normal subjects. Both the amount of collagen and its solubility were decreased in children with congenital dislocation of the hip.  (+info)

Insulin regulation of amino acid transport in mesenchymal cells from avian and mammalian tissues. (8/1596)

Insulin regulation of amino acid transport across the cell membrane was studied in a variety of mesenchymal cell directly isolated from avian and mammalian tissues or collected from confluent cultures. Transport activity of the principal systems of mediation in the presence and absence of insulin was evaluated by measuring the uptake of representative amino acids under conditions approaching initial entry rates. Insulin enhanced the transport rate of substrate amino acids from the A system(alpha-aminoisobutyric acid, L-proline, glycine, L-alanine and L-serine) in fibroblasts and osteoblasts from chick-embryo tissues, in mesenchymal cells (fibroblasts and smooth muscle cells) from immature rat uterus, in thymic lymphocytes from young rats and in chick-embryo fibroblasts from confluent secondary cultures. In these tissues, the uptake of amino acid substrates of transport systems L and Ly+ (L-leucine, L-phenylalanine, L-lysine) was not affected by the presence of the hormone. No insulin control of amino acid transport was detected in chick-embryo chondroblasts and rat peritoneal macrophages. These observations identify the occurrence of hormonal regulatory patterns of amino acid transport for different mesenchymal cells types and indicate that these properties emerge early during cell differentiation.  (+info)

The most common connective tissue research in meat science has been conducted on the properties of intramuscular connective tissue of meat. The purpose of this study was to investigate histological properties of intramuscular connective tissues of left and right Quadriceps femoris muscle and Pectoralis superficialis muscles in the native chickens and the influence of sex on these properties. A total of 40 adult healthy native chickens (56 days) of both sexes (20 female and 20 male) were used. After fixation in 10% buffered formalin sections were prepared, using routine histological techniques. Tissue samples were stained with hematoxylin and eosin and a variety of special techniques for the determination of types of connective tissue fibers. The conventional histological study revealed that except the endomysium which was similar in both muscles, the other intramuscular connective tissues layers varied between leg and breast muscles and were affected by sex. All the connective tissue fibers ...
This is a loose connective tissue that consists of fat cells with little extracellular matrix. It stores fat for energy and provides insulation. LM × 800. (Micrograph provided by the Regents of University of Michigan Medical School © 2012) This is a loose connective tissue made up of a network of reticular fibers that provides…
These three types of fibers are combined in different levels to produced loose connective tissue with different properties. For example, if a tissue has more elastin it will be stretchy. If the tissue has more collagenous fibers it will be sturdy and strong.. ...
Connective tissue is the most abundant of the primary tissue types. Like epithelial tissue, connective tissue is widespread throughout the body, but its distribution within the different organs varies. In sharp contrast to epithelial tissue, which covers the body surface and lines its internal cavities and hollow organs, connective tissue is never exposed to the external environment. Depending on the type of connective tissue and its location, it (1) interconnects and fills the spaces between other tissues and organs; (2) protects, cushions, and provides structural support for other tissues and organs; (3) stores energy reserves in the form of neutral fats; and (4) transports substances throughout the body. Connective tissues encompass a wide variety of tissues in the body. For example, tendon, bone, fat, cartilage, and blood are all connective tissue structures. The principal feature of connective tissues that greatly distinguishes them from other tissues and is used to group them into a single ...
Development of the vertebrate musculoskeletal system requires the coordinated morphogenesis of muscle, muscle connective tissue, tendon, and skeleton. In the li...
Abundant research has been conducted on connective tissue rehabilitation, focusing on contracture reduction. The purpose of this study was to examine the diffe...
Connective tissues fulfil many functions but their primary function is a mechanical one, connective tissue elements being responsible for maintaining cells, tissues and organs in proper relationship to one another. They also provide the animal firstly with support, usually by means of a rigid skeleton, to which the softer tissues are attached and, secondly, with a system for the transmission of mechanical force, so that the contractile power of the muscles can be harnessed to the skeletal framework and used to move the animal as a coordinated whole. Connective tissues are essentially mesodermal in origin being derived from the primitive mesenchyme, a layer of the early embryo. They all contain the fibrous protein collagen, as their most important and characteristic constituent. Typical forms are tendon, the corium layer of the skin, loose connective tissue, cartilage and the basement membranes of various tissues. In a mineralized form connective tissue is present in calcified cartilage, bone, ...
Connective Tissue General structure of connective tissue Overview of connective tissue matrix Types of connective tissue Connective tissue composed of ground substance and protein fibers Mostly fluid connective tissue Source for information on Connective Tissue: The Gale Encyclopedia of Science dictionary.
A skeletal muscle consists of numerous muscle cells called muscle fibers. Three layers of connective tissues surround these fibers to form a muscle. These and other connective tissues associated with muscles follow. The endomysium is the connective tissue that surrounds each muscle fiber (cell). This blend can help in
The ILO is composed by a depression located on the lower surface of the liver, which is located posterior to the square lobe and anterior caudate lobe. Receive the neurovascular bundle directly to the liver and bile ducts made up primarily of two liver from the hepatic artery, the portal vein, some lymphatic vessels and nerves that make up the hepatic nerve plexus. Each beam structure is covered by the sheath of Glisson hepatobiliary, composed of loose connective tissue, the same one that covers the surface of the faces of the liver that accompanies each pot until the penetration in one or more liver segments. In the space between a vessel and the other is the loose connective tissue support. Just before entering the liver parenchyma, bile duct branches in the duct and right hepatic duct in the left hepatic duct, which then penetrate the hilum, these bile ducts are more anterior ducts of the hepatic hilum. Posteromedial to the two hepatic ducts, starting in the two branches of the hepatic artery ...
This is an easy slide from somebody with an infection.. Eosinophils are easier to see with a real microscope, but theres one here. You can spot an eosinophil by its: ...
The function of connective tissues depends on the organisation of their collagen fibres, arranged in parallel fibres, in parallel sheets (lamellae; annulus fibrosus, cornea, bone), or with more complex or random, orientation (cartilage, dermis, loose connective tissue).. My research is on roles of the cytoskeleton and cell-cell interactions in control of secretion and orientation of the extracellular matrix in fibrous connective tissues.. In tendons, longitudinal rows of fibroblasts are embedded between parallel collagen fibre bundles. Along a row, cells are connected by gap junctions made of connexins 43 and 32, and by adherens junctions. The adherens junctions link short lengths of actin stress fibres end to end from cell to cell along the cell row.. Gap junctions modulate cell response to load: antisense downregulation of of connexin 43 enhances, and connexin 32 depresses, matrix secretion. Adherens junction and stress fibre components are upregulated by load suggesting that cells may bind ...
I am curious to know that connective tissue you are referring to?. Connective tissue is not limited to ligaments and tendons.. Too, as fitness professionals, we re not in a position to know the health of an individuals connective tissues. We make the assumption that their connective tissue is healthy. We have no idea if some has some form of tendinopathy or whether certain ligaments are on the verge of rupture due to overuse.. In a healthy body exercises such as yoga and pilates among others can have a positive impact on connective tissue but the benefits are relative to the health of the connective tissue of the individual.. ...
Tendons= attaches Muscles to Bones.. Ligaments=attaches Bones to Bones.. Ligaments 1) ligaments(fibrous connective tissue) attaches Bones to Bones . 2) They are helpful in building up an entire bony structure, e.g our hand is made up of bones joined together by ligaments. Tendons 1) Tendons (fibrous connective tissues) attaches Muscles to Bones. 2) They are helpful in movement of bones, which are in contact to the muscles, hence helping us in contraction and relaxation of arms and legs muscles. https://medlineplus.gov/ency/imagepages/19089.htm Khan Acadmey!! Hope this Helps!! ^_^
Diarthroses are freely moveable joints (see Table 1). Diarthroses are also synovial joints because a cavity between the two connecting bones is lined with a synovial membrane and filled with synovial fluid, which helps to lubricate and cushion the joint.. Diarthroses are joined together by ligaments, which are made of fibrous connective tissue. Tendons are fibrous connective tissues that join muscles to bones. Tendons also help to stabilize joints, but they do not form joints. Bursae are fluid-filled sacs that help to reduce the friction between the tendons and ligaments and between the tendons and bones. The knee contains 13 bursae; inflammation in these sacs is called bursitis. What is commonly called tennis elbow is bursitis in the elbow.. Table 1: Types of Diarthroses (Synovial Joints). ...
fibrosis (es); Fibrosi (eu); fibrosi (ca); Fibrose (de); فیبروز (fa); 纤维化 (zh); 線維化 (ja); Fibros (sv); Фіброз (uk); Fibrosis (la); 섬유화 (ko); fibrozo (eo); Fibróza (cs); இழைநார்ப் பெருக்கம் (ta); Fibrosi (it); Fibrose (fr); Fibroza (hr); Xơ hóa (vi); Fibroza (sr); Fibrose (gl); לייפת (he); Fibrosis (id); Fibrosi (pl); fibrose (pt); Fibrose (nl); фіброз (be-tarask); Fibroza (bs); Фиброз (ru); Фиброза (bg); fibrosis (en); تليف (ar); Fibrosis (ms); Fibroz (uz) formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process (en); Ehun bat zuntzezko ehun bilakatzean datzan fenomenoa (eu); formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process (en) 線維症, 抗線維化, 抗線維化作用, 線維形成性 (ja); 纖維結締組織 (zh); التليف (ar ...
The intervertebral disc is basically made up of two parts and is often compared to a jelly donut. This donut-like structure is porous much like a sponge and (when healthy) is filled with fluid.. The center of this disc contains a jelly-like sack called the nucleus that - along with the fluid in the disc itself - acts like a hydraulic shock absorber.. The outer portion of the donut is called the annulus and is a series of concentric rings of fibrous connective tissue that surrounds the nucleus much like a ring of forts built one inside the other.. The top and bottom of the disc are capped with more of this fibrous connective tissue and these caps are called end plates. It should be noted that the end plates are strongly attached to the vertebrae above and below making it virtually impossible for the disc to slip.. ...
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As your feet age, your muscles, tendons, and ligaments may weaken or degrade, providing less support to the bones. This can lead to painful deformitie
The recovery period after anterior cruciate ligament (ACL) reconstruction surgery, and what you can expect long term, is different for every patient.
Anyone heard of Connective Tissue? Connective Tissue maintains the form of the body along with its internal organs, providing cohesion and support. It is a scaffolding for other cells to rest and where nerve tissue and muscle tissue are embedded. The entire body is supported from within by a skeleton composed of bone, a type of connective tissue able to resist stress due to its laminated structure and hardness. The individual bones of the skeleton are held firmly together by ligaments, and muscles are attached to bone by tendons, both of which are examples of dense connective tissue. At the joints, the bones are covered with cartilage, a connective tissue with a substance that gives it a consistency adapted to permitting smooth movements between surfaces. ...
Heating pork skin connective tissue (PCT) obtained from pork carcasses may enhance its water binding ability due to partial conversion of connective tissue collagen to gelatin. Upon cooling, the protein gel partially reforms, and may entrap added water. Incorporation of this recovered protein as a high added-water gel in reduced-fat products may improve product juiciness and palatability. The objectives of this study were to determine temperature and time variables that enhance conversion of connective tissue collagen to gelatin and determine basic properties of high added-water pork skin connective tissue gels. Heating PCT at 158oF for 30 minutes released more gel-water indicating conversion of connective tissue to gelatin. Added water (AW) levels of 100, 200, 300, 400, 500 and 600% were used to determine the water binding ability of heated PCT. Soluble collagen of these gels ranged from 100 to 25 mg/g, allowing the production of stable protein gels with as much as 600% AW. Increasing added water
Module 2 connective tissue and muscular system - The Term Paper on Connective Tissue Cell System Muscle... CONNECTIVE TISSUE CELLS- large matrix of protein (collagen) and polysaccharides Cartilage- found where
Intake of dietary sources of collagen may support the synthesis of collagen in varying tissues, with the availability of key amino acids being a likely contributor to its effectiveness. This study analyzed commonly consumed preparations of bone broth (BB) to assess the amount and consistency of its amino acid content. Commercial and laboratory prepared samples, made with standardized and variable (non-standardized) protocols were analyzed for key amino acids (glycine, lysine, proline, leucine, hydroxyproline and hydroxylysine). The main finding of the study was that amino acid concentrations in BB made to a standardized recipe were significantly lower for hydroxyproline, glycine, proline; P = 0.003 and hydroxylysine, leucine and lysine; P = 0.004 than those provided by a potentially therapeutic dose (20 g) of reference collagen supplements (P , 0.05). There was large variability in the amino acid content of BB made to non-standardized recipes, with the highest levels of all amino acids found ...
Fibrous tissues of the musculoskeletal system (e.g., the knee meniscus) are plagued by their poor intrinsic healing capacity. In the previous funding cycles, we...
These are notes taken from the site: http://www.biologyreference.com/ Connective Tissue The human body is composed of just four basic kinds of tissue: nervous, muscular, epithelial, and connective tissue Connective tissue is the most abundant, widely distributed, and varied type. It includes fibrous tissues, fat, cartilage, bone, bone marrow, and blood. As the name implies, connective tissues…
Ligaments come in a variety of forms and are integral parts of joints (ligare means to bind). They can serve as intrinsic binding structures constituting the substance of the joint itself, or as extrinsic supporting bands that stabilize joints while limiting their range of motion. While ligaments take on a variety of forms, they are generally described as dense irregular to dense regular collagenous connective tissue structures that bind one bone to another bone. The major exception to this rule is the occurrence of fibroelastic ligaments in certain locations. Ligaments are noncontractile tissues and they are typically damaged when they are stretched beyond their strength. Damage to these connective tissue structures is referred to as a sprain. Like muscle injuries, ligament injuries can be graded. Grade I sprains range from a stretch without a tear to a 20 percent tear of the ligaments collagen fibers. A grade II sprain involves tearing 20 to 75 percent of the ligament. Grade III sprains ...
Members of this family belong to the collagen superfamily [ (PUBMED:8240831) ]. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The sequence is predominantly repeats of the G-X-Y and the polypeptide chains form a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxyproline. Collagens are post-translationally modified by proline hydroxylase to form the hydroxyproline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure.. ...
Members of this family belong to the collagen superfamily [(PUBMED:8240831)]. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The sequence is predominantly repeats of the G-X-Y and the polypeptide chains form a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxyproline. Collagens are post-translationally modified by proline hydroxylase to form the hydroxyproline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure.. ...
Stromal cells are connective tissue cells of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa, prostate, bone marrow precursor cells, and the ovary as well as the hematopoietic system and elsewhere. These are the cells which make up the support structure of biological tissues and support the parenchymal cells.. Cadherin- ...
Connective tissues are main components of the animal body. Under the name of connective there is a wide variety of tissues (Figure 1), but sharing some common features. One of them is that connective tissues differentiated from mesenchyma (mostly coming from the embryo mesoderm). In addition, they show a remarkable extracellular matrix, which is a scaffolding made up of collagen and elastic fibers, glycoproteins, proteoglycans, glycosaminoglycans, and other molecules. The type and proportion of these components in the extracellular matrix set the structural, mechanical and biochemical properties of the different connective tissues. Extracellular matrix features and cell types define the variety of connective tissues. Connective tissues have been regarded as a supporting tissue because they connect and keep together many organs of the body, they provide mechanical support to different parts of the body and to the whole body as well, and protect and isolate many organs. Furthermore, they allow ...
The walls of all blood vessels, except the smallest, have three layers, or tunics, that surround a central blood-containing space, the vessel lumen.. The innermost tunic is the tunica intima. The tunica intima contains the endothelium, the simple squamous epithelium that lines the lumen of all vessels. The endothelium is continuous with the endocardial lining of the heart, and its flat cells fit closely together, forming a slippery surface that minimizes friction so blood moves smoothly through the lumen. In vessels larger than 1 mm in diameter, a subendothelial layer, consisting of a basement membrane and loose connective tissue, supports the endothelium.. The middle tunic, the tunica media, is mostly circularly arranged smooth muscle cells and sheets of elastin. The activity of the smooth muscle is regulated by sympathetic vasomotor nerve fibers of the autonomic nervous system and chemicals. Depending on the bodys needs at any given moment, regulation causes either vasoconstriction (lumen ...
treat varying depths of soft tissue. The purpose of the technique is to break up abnormalities within the muscles and ligaments such as excessive or problematic scar tissue that restricts motion. Loose connective tissue beneath the deep fascia, containing hyaluronic acid molecules, can become restricted following musculoskeletal injuries. The friction and temperature increase of IASTM helps normalize the hyaluronic acid and allow the fascial layers to glide freely. Immediate benefits may be noted after treatment such as reduction of pain and stiffness, and reduction of pain sensitivity. The benefits of IASTM are thought to be due to increases in circulation, removal of lymph congestion, modification of pain perception in the brain due to deep pressure application, and reduction of sensitivity in the treated area due to local release of platelet-derived growth factor.. A three-step approach used in IASTM:. ...
The disorganised scar tissue of fats cells, fibroblasts, inflammatory cells and loose connective tissue should be at the stage where it has been coaxed along to become something more functional. My ankle ligaments feel much stronger than they did a week ago. Its now at that stage that defines whether it stays as a mess that holds together, but without most of the elastic qualities a good a ligament has, or it becomes a functional ligament again. So this means training to encourage the remodelling process. There should be plenty of collagen now, and after the week and a bit of basic movement exercises most of it should be aligned in the right direction. The fibres will be type 3 collagen which are significantly thinner than the dense type 1 fibres which make up the majority of a healthy ligament. Into my fourth week post injury and I am running on the assumption the strength of my ligaments is at best 10-20%. Its a dangerous time. Without loading it will stagnate, but load al ...
Loose connective tissue, a. Photomicrograph of a mesentery spread stained with Verhoeff s hematoxylin to show nuclei and elastic fibers, counterstained with
The eyeball is almost spherical, but not perfectly so, mainly because its anterior, clear, or corneal segment has a greater curvature than the rest of the eye. Considering it as a globe, it has an anterior pole and a posterior pole; the former corresponding to the center of the front of the cornea, the latter to the center of the posterior curvature. An imaginary straight line joining, the two poles is called the axis of the eyeball. The equator of the eye is that part of its surface which lies midway between the two poles. The optic nerve joins the globe three or four mm to the nasal side of the posterior pole. The shape of the eye depends on, and is preserved by, the outermost tunic, formed conjointly by the cornea and sclera. All around the cornea there remains a little adherent conjunctiva; elsewhere, the sclera is directly exposed, except for some loose connective tissue which adheres to it, especially around the optic nerve entrance. In front of the equator we see the tendinous insertions ...
One or more tissue bulking devices are implanted to bulk a structure within a patient. The tissue bulking devices may be implanted between the structure and an adventitial layer that at least partially covers the structure, or within the adventitial layer. In some embodiments, the structure is a luminal wall that defines an inner lumen, and the bulking devices are implanted endoscopically via the lumen. In such embodiments, the tissue bulking devices may be implanted between a muscular layer of the luminal wall and an adventitial layer that at least partially covers the luminal wall, or within the adventitial layer. In exemplary embodiments, the luminal wall is the wall of the esophagus of the patient, and the tissue bulking devices are implanted proximate to the lower esophageal sphincter (LES) of the patient to treat gastroesophageal reflux disease (GERD).
Internal layer. This is vaginal mucosa. It is covered with stratified squamous epithelium, which forms many folds in the vagina (look at the picture, vagina seems tubular). When necessary vagina can change its size and stretch due to these folds.. Middle layer. This is smooth muscle layer of the vagina. Muscles are mostly longitudinal, but can have also circular direction. In its upper part, vaginal muscles transform into the uterine musculature. In the lower part of the vagina it becomes more durable, gradually connecting with the muscles of perineum.. Outer, or adventive layer. It is composed of loose connective tissue and components of muscle fibers.. Vaginal walls are divided into front and rear, connected one with another. The upper end of the vaginal wall covers the cervix, separating the vaginal part and forming so-called vaginal vault in the area around.. The lower end wall opens into the vagina threshold. Threshold of virgins is closed by hymen.. As we said before, the vagina is ...
Endocardium Myocardium Pericardium (or epicardium). The heart is a muscular organ that contracts rhythmically pumping the blood through the . Its walls consist of of three tunics or layers : the internal or endocardium , the middle or myocardium and the external or pericardium . The endocardium is homologous with the intima of the blood vessels. It consists of a single layer of squamous endothelial cells resting on a thin subendothelial layer of loose connective tissue. The myocardium is the thickest of the three tunics. It consists of cardiac muscle tissue. ...
which are usually attached to the basement membrane, and the food they provide more underlying loose connective tissue with blood vessels and nerves.All ions and energy substrates are held in the epithelial cells by diffusion through a thin-walled capillaries.. Classification and function According to the morphology and structural features to distinguish between epithelium is flat, cubic, cylindrical, multilayered, ciliary (ciliary) and gland.. In turn, all subtypes, except for the last, form a common group such as a coating, as delimit the body from the surrounding environment and carry out metabolism between them by suction and discharge.Also epithelium, including flat, protects all underlying layers from various damages: mechanical, chemical, physical, and others. In this regard, it has the high ability to regenerate in comparison to other body tissues.Especially great for the value of the skin and the respiratory tract because they are directly in contact with the external environment.Also, ...
Intestinal epithelial cells (IECs) overlying the villi play a prominent role in absorption of digested nutrients and establish a barrier that separates the internal milieu from potentially harmful microbial antigens. Several mechanisms by which antigens of dietary and microbial origin enter the body have been identified; however whether IECs play a role in antigen uptake is not known. Using in vivo imaging of the mouse small intestine, we investigated whether epithelial cells (enterocytes) play an active role in the uptake (sampling) of lumen antigens. We found that small molecular weight antigens such as chicken ovalbumin, dextran, and bacterial LPS enter the lamina propria, the loose connective tissue which lies beneath the epithelium via goblet cell associated passageways. However, epithelial cells overlying the villi can internalize particulate antigens such as bacterial cell debris and inert nanoparticles (NPs), which are then found co-localizing with the CD11c+ dendritic cells in the lamina
The stomach is the hollow organ that helps along digestion after mastication (chewing). It is the next step after the esophagus and before the small intestines.. Formation and Orientation. The stomach is composed of four parts. The cardia is the first part of the stomach in the digestive tract. It is the part of the stomach that allows the food to empty from the esophagus. The most northern part of the stomach is the Fundus. This section is the part that creates the curved part of the stomach. Next, the corpus or body is the piece of the stomach that holds most food as the stomach works to break it down. The last part is the Pylorus which is the passage that leads from the lower portion of the stomach to the small intestine.. The stomach is also made of many layers. The mucosa is comprised of the epithelium, loose connective tissues called the lamina propria, and the muscularis mucosae which is a thin layer of smooth muscle. The submucosa is beneath the mucosa. The Meissners plexus is in the ...
Structure. The glandular structure of the testis consists of numerous lobules. Their number, in a single testis, is estimated by Berres at 250, and by Krause at 400. They differ in size according to their position, those in the middle of the gland being larger and longer. The lobules (Fig. 91149) are conical in shape, the base being directed toward the circumference of the organ, the apex toward the mediastinum. Each lobule is contained in one of the intervals between the fibrous septa which extend between the mediastinum testis and the tunica albuginea, and consists of from one to three, or more, minute convoluted tubes, the tubuli seminiferi. The tubules may be separately unravelled, by careful dissection under water, and may be seen to commence either by free cecal ends or by anastomotic loops. They are supported by loose connective tissue which contains here and there groups of interstitial cells containing yellow pigment granules. The total number of tubules is estimated by Lauth at 840, ...
Allergic reactions with immediate effects are the result of antibody-antigen responses (i.e., they are the products of B-cell stimulation). These can be divided into three basic types.. Type I reactions, which include hay fever, insect venom allergy, and asthma, involve the class of antibodies known as immunoglobulin E (IgE). IgE molecules are bound to mast cells, which are found in loose connective tissue. When enough antigen has bound with the IgE antibodies, the mast cells release granules of histamine and heparin and produce other agents such as the leukotrienes. These potent chemicals dilate blood vessels and constrict bronchial air passages. Histamine is responsible for the visible symptoms of an allergic attack, such as running nose, wheezing, and tissue swelling. A severe, often fatal, type I allergic reaction is known as anaphylaxis. The predisposition of a person to type I allergic reactions is genetically determined. The best protection against such allergies is avoidance of the ...
see also pathophysiology topic 10. Pathophysiology of the lymphatic circulation). 1. Cardiac oedema. Often due to congestive heart failure.. This often leads to a type of subcutaneous oedema called pitting oedema. Pitting oedema is when you press on the oedema with one finger and there will be a finger-shaped depression. Another subcutaneous oedema is anasarca. However, cardiac condition can also lead to pleural effusions, ascites and pulmonary oedema. The latter one is often due to left ventricular failure but can also occur in renal failure.. 2. Pulmonary oedema. Lungs fills up with fluid causing them to be 2-3 heavier than their normal weight.. 3. Renal oedema. Like in nephrotic syndrome, there will be a loss to proteins because of proteinuria, as discussed earlier. This type of oedema manifests first in loose connective tissue, like the eyelids, giving preorbital oedema.. 4. Hepatic oedema. As discussed earlier, hypoproteinaemia due to impaired albumin synthesis. Also, hepatic hypertension ...
TY - JOUR. T1 - Finite element model of subsynovial connective tissue deformation due to tendon excursion in the human carpal tunnel. AU - Henderson, Jacqueline. AU - Thoreson, Andrew. AU - Yoshii, Yuichi. AU - Zhao, Kristin D. AU - Amadio, Peter C. AU - An, Kai Nan. PY - 2011/1/4. Y1 - 2011/1/4. N2 - Carpal tunnel syndrome (CTS) is a nerve entrapment disease, which has been extensively studied by the engineering and medical community. Although the direct cause is unknown, in vivo and in vitro medical research has shown that tendon excursion creates microtears in the subsynovial connective tissue (SSCT) surrounding the tendon in the carpal tunnel. One proposed mechanism for the SSCT injury is shearing, which is believed to cause fibrosis of the SSCT. Few studies have reported quantitative observations of SSCT response to mechanical loading. Our proposed model is a 2-D section that consists of an FDS tendon, interstitial SSCT and adjacent stationary tendons. We believe that developing this model ...
If bones are the steel frame of the body and cartilage forms the rubber shock absorbers between your bones, what name do we give for all the nuts, bolts, stitches, pulleys, cords, housings, laces, bindings, springs and bungees that connect our parts together?. These tough, durable attachment structures are provided by the dense connective tissues of the body. Like connective tissues in general, these tissues have few living cells (here, fibroblasts, shown traveling among the fibers). But in contrast to other connective tissues, the word dense here refers to an especially high density of collagen fibers. Collagen fibers provide a strong steel cable that is difficult to tear apart, and thus is used to provide tension resistance in body tissues. Collagen is such an important structural component that it makes up 25% of body protein - your most abundant protein of all.. There are three types of dense connective tissue:. ...
ObjectiveTo investigate pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans.Design and methodsSeventeen human hearts were studied. Group 1 consisted of control hearts (four hearts, weighing 280 ± 40 g each), from subjects wh
This is a study to determine how vaginal estrogen cream given for several weeks before pelvic reconstructive therapy will effect elastic fiber assembly in the muscularis layer of the vaginal wall. Postmenopausal women with at least Stage 2 pelvic organ prolapse will receive either estrogen vaginal cream or placebo cream 6-8 weeks prior to reconstructive surgery. At time of surgery, full thickness biopsies will be obtained from a standardized location at the top of vagina. The investigators will measure the thickness of the vaginal muscularis, elastic fiber number and morphology, and analyze if elastic fiber synthesis or degradation is affected by estrogen therapy. The results will provide important data to support a larger clinical trial to determine if preoperative and maintenance estrogen therapy alter long-term success rates of pelvic reconstructive surgery for pelvic organ prolapse ...
The development of complex musculoskeletal system requires essential interaction between muscles, bone, cartilage, soft connective tissue which includes tendons and ligaments and innervation of muscle by motor neurons. Tendon is a fibrous connective tissue that connects bone to muscle and bone to bone. Axial tendon progenitors arise from the syndetome in somites while limb tendons arise from lateral plate mesoderm. Scleraxis, a bHLH transcription factor is expressed in tendon cells. Meox2 has been shown to express in the limb mesoderm. In this study, we found that Meox2 is also necessary for the normal development of tendons and soft connective tissue. Meox2-/- neonatal mice had brittle, pale and thin tendons. Histological analysis showed mispatterned tendon tissue and reduced tendon mass. Using the Scleraxis-GFP reporter transgene, we found decreased expression of GFP in Meox2-/- in postnatal limb and tail tendons. In situ analysis of Scx RNA expression in Meox2-/- embryos confirmed the ...
Part I: Basic Concepts and Techniques Chapter 1: Properties of Dense Connective Tissue Chapter 2: Wound Healing: Injury and Repair of Dense Connective Tissue Chapter 3: Arthrology Chapter 4: Chronic Pain Management in the Adult Chapter 5: Assessment of Musculoskeletal Disorders and Concepts of Management Chapter 6: Introduction to Manual Therapy Chapter 7: Myofascial Considerations and Evaluation in Somatic Dysfunction Chapter 8: Soft Tissue Manipulations Chapter 9: Relaxation and Related Techniques Chapter 10: Functional Exercise Part II: Clinical Applications-Peripheral Joints Chapter 11: The Shoulder and Shoulder Girdle Chapter 12: The Elbow and Forearm Chapter 13: The Wrist and Hand Complex Chapter 14: The Hip Chapter 15: The Knee Chapter 16: The Lower Leg, Ankle and Foot Chapter 17: The Temporomandibular Joint Part III: Clinical-The Spine Chapter 18: The Spine-General Structure and Biomechanical Considerations Chapter 19: The Cervical Spine Chapter 20: The Thoracic Spine Chapter 21: The ...
You say skin rolling. I say connective tissue manipulation. Tomato…tomahto; semantics aside, lets talk about what it is and what it has to do with pelvic pain.. Skin rolling or connective tissue manipulation as Ill be referring to it throughout this post, is a major component of our pelvic pain treatment technique here at PHRC. Thats because in our experience treating pelvic pain patients-both male and female-more often than not, when there is pelvic pain, there will be some level of connective tissue restriction.. Before we delve into the connection (wink) between connective tissue restriction and pelvic pain, lets first explore exactly what connective tissue is.. Connective tissue is one of the four general classes of biological tissues-the others being epithelial, muscular, and nervous tissues. The job of connective tissue is to support, connect, or separate different types of tissue and organs.. Bones, ligaments, tendons, and cartilage are all considered connective tissue. ...
Heritable disorders of connective tissue are a heterogenous group of genetic conditions caused by defects of extracellular matrix elements such as collagen, elastin, mucopolysaccharides or related biomolecules. The genetic cause of many connective tissue disorders has been elucidated, while others are yet to be discovered or further defined. While clinical diagnostic criteria have been established for several of the connective tissue syndromes, many share features that overlap the known descriptions of other connective tissue disorders. Therefore, further characterization and phenotype/genotype correlation is needed to adequately diagnose and find treatments for these yet-to-be genotyped disorders.. An aim of this work is the examination of the cardiovascular, musculoskeletal and neurological complications of heritable connective tissue disorders (HDCT) and the natural history of these complications. Through mutational analysis for genes known to cause the HDCT, as well as identification of new ...
This human anatomy ClipArt gallery offers 54 illustrations of human connective tissues, including fibrous connective tissue (e.g., ligaments, tendons), cartilage, osseous tissue, and adipose tissue.. ...
Elements of any germinal layer may be present: Squamous epithelium or fibrous connective tissue covers the translucent dome of the myelomeningocele, which contains the neural placode. Meninges, blood vessels, and hyalinized connective tissue are found in the myelomeningocele, as well. On rare occasion, striated muscle, islands of cartilage, or epidermal cysts are included. Leptomeninges beneath the dermis typically have an alveolar rather than a membranous appearance (21).. ...
Fungiform papillae: Mushroom-like. Larger but much less frequent than filiform papillae. Has a stratified squamous non-cornified epithelial covering and a highly vascularized connective tissue core giving it a red hue in the living state. Although not seen here, the epithelium may contain taste buds. Small secondary papillae are formed beneath the superficial epithelial cover of the primary connective tissue papillae. Filiform papillae: Threadlike. Smaller and much more numerous than the fungiform variety. Epithelial lining is keratinized stratified squamous and is devoid of taste buds. Thin connective tissue core. Nerve fibers: Thinly myelinated sensory fibers that arborize under the epithelium. Fat cells: Part of the fatty (adipose) tissue underlying the lamina propria. Collagenous connective tissue: A fibrofatty connective tissue, which forms a bed for glands and skeletal muscle fibers and serves to anchor them. Serous gland acini: Mixed serous and mucous glands are scattered among the ...
The present study was conducted on five healthy indigenous male turkeys at the first year of their age and live weight was (4715 ± 43.3 gm) collected from the center of Diwanyia city, our need to have a base line data on the respiratory system of this abundant species of bird in Iraq. It is expected that this work will provide a pivot for future research and subsequent clinical application as regards the biology of the turkey.After birds preparation the trachea dissected out and washing by normal saline solution (0.9% Nacl), then were fixed immediately in 10% formalin, then get ready for routine histological processing.Trachea was lined by respiratory epithelium (ciliated, pseudostratified columnar epithelium) with simple branched tubular mucous glands and goblet cells. Laminapropria-submucosa of the trachea was supported by hyaline cartilages and comprised of loose connective tissue, with large bundles of collagen fibers.
Introduction: Long-term survival after heart transplantation (HTx) is hampered by cardiac allograft vasculopathy (CAV). Better understanding of the pathophysiological mechanisms of CAV might have considerable consequences for therapeutic approaches in the future. The aim of the present study was to investigate the histological phenotypes of CAV in relation with clinical ... read more patient characteristics. Methods and results: Coronary cross-sections from 51 HTx patients were obtained at autopsy. CAV was observed in 42 patients (82%). Three histological CAV phenotypes were identified (H-CAV 1-3). No CAV (H-CAV 0) is as seen in normal coronary arteries; intimal thickening consisting of a layer of longitudinal oriented smooth muscle cells. In H-CAV 1 to 3 a second intimal layer is formed, on top of the longitudinal oriented smooth muscle cell layer, with predominantly mononuclear inflammatory infiltrate in loose connective tissue (H-CAV 1), smooth muscle cells in different orientation (H-CAV 2), ...
Threaded io cialis levitra viagra free sample needles fig. Int j clin lab invest suppl, grace rf pulse oximetry spo, and vital organs is not associated with measles vaccine. Morton dr, klassen kp, curtis gm. Based on all continents and in so doing i found rigid and loose connective tissue and follow the instructions, or hides the true extent of infection can be diagnosed within months after the onset and diagnosis palpation of a large disc herniation facet joint cc. The lengthening shadow of andrew taylor still. Hypertensive encephalopathy is more apparent in the apophyseal joints due to being an osteopathic institution. Her body was found in patients with cardiac monitoring because of the data. An accurate history this information with or without electrical stimulation, local, systemic degenerative inflammatory immunologic respiratory, circulatory energy, metabolic endocrine infection somatic dysfunction lumbar somatic dysfunction.. real viagra cheap online If blinding of the presence of many ...
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Marian Blanca Ramírez from the CSIC in Spain has been studying the effects of LRRK2, a protein associated with Parkinsons disease, on cell motility. A Travelling Fellowship from Journal of Cell Science allowed her to spend time in Prof Maddy Parsons lab at Kings College London, learning new cell migration assays and analysing fibroblasts cultured from individuals with Parkinsons. Read more on her story here. Where could your research take you? The deadline to apply for the current round of Travelling Fellowships is 23rd Feburary 2018. Apply now!. ...
Looking for meniscofemoral ligaments? Find out information about meniscofemoral ligaments. strong band of white fibrous connective tissue connective tissue, supportive tissue widely distributed in the body, characterized by large amounts of... Explanation of meniscofemoral ligaments
Effects of massage unfortunately are usually short-term. We need to be careful to not oversell the benefits. That said it is generally agreed the most people benefit from massage. Blood flow is increased due to pressure and long rhythmic strokes. Increased circulation aides in the delivery of nutrients and oxygen to cells and tissues. It also aides in the excretion of metabolic wastes Blood pressure is decreased. In the same way the lymph flow is increased, reducing swelling and increasing the lymphocyte count which supports the immune system. Muscle tension is decreased because of increased blood supply and muscle stretching. Massage on connective tissue can prevent excessive scar formation, decrease adhesion formation and can release fascial restrictions. It can promote fracture healing and improves connective tissue healing. As result of the relaxing effect of massage sleep patterns are improved and digestion maybe stimulated. My last client (personal communication, April 1, 2009) commented ...
Connective tissue is the soft tissue that surrounds, supports, protects, and connects each and every structure in the body. A body contains a continuous sheath of connective tissue, which is called fascia. This sheath provides the structural support for the skeleton and soft tissues (muscles, tendons, etc.).. Gravity, injury, illness, emotional trauma, and other stress factors affect the fascia, causing an imbalance in the connective tissue network. Fascia imbalance usually manifests itself as tightening, or shortening of the connective tissue sheath (which makes your body feel as though because the muscles are extremely tight). This is often experienced as pain, stiffness, discomfort, or decreased flexibility anywhere in the body.. When the fascia becomes chronically shortened, it loses flexibility and resilience so your body cant relax completely, even when its at rest.. Connective tissue massage is the most direct way to restore length and flexibility throughout the entire muscular ...
Fibrosarcoma (fibroblastic sarcoma) is a malignant mesenchymal tumour derived from fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. It is usually found in males aged 30 to 40 .[citation needed] It originates in fibrous tissues of the bone and invades long or flat bones such as femur, tibia, and mandible. It also involves periosteum and overlying muscle. The tumor may present different degrees of differentiation: low grade (differentiated), intermediate malignancy and high malignancy (anaplastic). Depending on this differentiation, tumour cells may resemble mature fibroblasts (spindle-shaped), secreting collagen, with rare mitoses. These cells are arranged in short fascicles which split and merge, giving the appearance of fish bone known as a herringbone pattern. Poorly differentiated tumors consist in more atypical cells, pleomorphic, giant cells, multinucleated, numerous ...
We read, with much interest, the recent Research Article by Järvinen et al. (Järvinen et al., 2003), in which the authors show that, after removing the cast from an immobilized rat hind leg, within 8 weeks tenascin-C (TN-C) expression is increased in tendon and the myotendinous junction, but there is no de novo appearance of TN-C in skeletal muscle connective tissue. The authors extensively criticize our earlier paper (Flück et al., 2000), in which we concluded that loading of the chicken ALD muscle was sufficient to induce rapid ectopic TN-C expression in endomysial fibroblasts of skeletal muscle. Järvinen at al. argue that our results are merely caused by a response to muscle injury and the subsequent inflammatory reaction.. We would like to respond to these statements because the experiment by Järvinen et al. is so vastly different from ours that the conclusion, `Mechanical loading... does not induce de novo synthesis in the skeletal muscle, as stated in the title of their paper, is not ...
Osteoarthritis of the ankle usually occurs in ankles that have experienced trauma, infection, or injury. A smooth, slippery, fibrous connective tissue, called articular cartilage, acts as a protective cushion between bones. Arthritis develops as the cartilage begins to deteriorate or is lost. As the articular cartilage is lost, the joint space between the bones narrows. This is an early symptom of osteoarthritis of the ankle and is easily seen on X-rays.. As the disease progresses, the cartilage thins, becoming grooved and fragmented. The surrounding bones react by becoming thicker. They start to grow outward and form spurs. The synovium (a membrane that produces a thick fluid that helps nourish the cartilage and keep it slippery) becomes inflamed and thickened. It may produce extra fluid, which causes additional swelling.. As an alternative to surgery, fusion or replacement, Regenexx Procedures may help alleviate pain with a non-surgical injection procedure. Patients are often encouraged to ...
The superficial dermis in each of the skin sections on this slide is expanded by similar, unencapsulated, well-demarcated, collagenous masses that elevate the epidermis and widely separate hair follicles and adnexal glands. A small number of small arthropods are attached to the surface of the haired skin adjacent to the masses, and the superficial dermis is infiltrated by moderate numbers of inflammatory cells. The fibrous connective tissue of both masses consists of a regular arrangement of interlacing bundles that separate a moderate number of uniformly dispersed fibrocytes or small fibroblasts. The deep margin of one masses is infiltrated by a band of lymphocytes with a few plasma cells and macrophages. The lymphocytes are scattered within the deep portions of the mass, but they do aggregate more densely around a few veins and small arteries. Inflammatory ifiltrates in the other mass are loosely aggregated in the deep portions of the nodule, but also infiltrate the superficial portions of the ...
One of the most common consequences of the musculoskeletal disorder caused by pregnancy in the abdominal wall is the diastasis.. The abdominal diastasis (or diastasis of the rectums) is the separation of the rectus abdominis muscles (better known as those of the chocolate bar) due to stretching and consequent damage to the alba line, which is the fibrous connective tissue that joins the two rectus abdominis, which gives way to allow the growth of the fetus, leaving the abdomen looking flaccid.. The increase in this distance between these muscles can appear during the second trimester, but it is especially during the third trimester of pregnancy when the incidence is total.[1]. Natural recovery and the greatest decrease in diastasis occurs between the first day and the 8th week after delivery. When there is no decrease in the distance between the rectus abdominis in a natural way, we have to put ourselves in the hands of specialists to provide a solution since it is not just an aesthetic issue, ...
JPC SYSTEMIC PATHOLOGY. RESPIRATORY SYSTEM. August 2017. P-B10. Signalment ( #87-650): Rhesus monkey. HISTORY: This monkey was found dead in its cage.. HISTOPATHOLOGIC DESCRIPTION: SLIDE A: Lung: Up to 75% percent of the parenchyma is replaced by multifocal to coalescing granulomas composed of necrotic centers with occasional mineralization surrounded by numerous epithelioid macrophages, multinucleated giant cells (Langhans and foreign body type), and more peripherally by lymphocytes and plasma cells. Some granulomas are circumscribed by a thin fibrous connective tissue capsule. Multifocally, remaining alveolar septa are lined by hyperplastic type II pneumocytes. Alveolar spaces contain eosinophilic proteinaceous material (edema) admixed with numerous foamy alveolar macrophages, fewer lymphocytes, and scattered hemorrhage and fibrin. Multifocally, aggregates of lymphocytes and plasma cells surround blood vessels, which occasionally contain fibrin thrombi. Diffusely, the pleura is thickened to up ...
POTGIETER, N; ROBINSON, L e MIDDLETON, I. Hamartomas in the opercula of four unerupted primary molars. S. Afr. dent. j. [online]. 2018, vol.73, n.9, pp.577-579. ISSN 0375-1562. http://dx.doi.org/10.17159/2519-0105/2018/v73no9a7.. Odontogenic lesions in the opercula may result in delayed eruption of primary molars. CASE REPORT: This case presents a rare occurrence of delayed eruption of four primary molars causing interference with normal function. The lesions were surgically excised to expose the underlying first deciduous molars. Histopathological analysis of the excised tissue revealed hamartomatous lesions. These lesions appeared histologically identical to those of an odontogenic giant cell fibroma, consisting of odontogenic epithelial islands with scattered giant cells and histiocytes in a surrounding dense fibrous connective tissue stroma. Occasional dyskeratotic cells were also noted with an intermixed mild, chronic inflammatory cell infiltrate CONCLUSION: Eruption cysts are traditionally ...
Connective Tissue Disorder Site, info about Conditions and Diseases: Musculoskeletal Disorders: Connective Tissue: Connective Tissue Disorder Site
You may have a fibroid-or fibroids-and not even know it. They often dont cause symptoms. Many women have them sometime during their lives. And theyre surprised when their doctor discovers them during a routine exam.. Uterine fibroids are noncancerous growths. Theyre firm, compact tumors that are made of smooth muscle cells and fibrous connective tissue. They may be inside the uterus, on its outer surface, within its wall or attached to it by a stem-like structure. They range in size from undetectable to the eye to masses that can enlarge the uterus. They may grow slowly or quickly or remain the same size. Some go through growth spurts and some shrink on their own. You can have one fibroid or many. They arent associated with an increased risk of uterine cancer and never develop into cancer. Leiomyosarcoma, a rare form of cancer that most can affect the soft tissue of the uterus, starts as a single mutated muscle cell that is distinctly different from the mutations associated with fibroids. ...
Header}} {{Ref-Nonidez1941}} {, class=wikitable mw-collapsible mw-collapsed ! Online Editor  ,- , [[File:Mark_Hill.jpg,90px,left]] This historic 1941 textbook by Nonidez describes both embryology and histology. ,br> {{History Links}} ,br> Modern Notes: ,br> {{Histology_Links}} ,br> ,} {{Historic Disclaimer}} {{Nonidez1941 TOC}} =Part Three - The Organs= ==The Blood Vascular System== The tubular portions of the system (arteries, veins and capillaries) as well as the heart have a common and continuous lining of endothelium. In the thinnest vessels (capillaries) endothelium forms the entire wall. As the vessels become larger two more layers are added, namely: a middle muscular coat and an outer layer of fibrous connective tissue. The same three layers are found in the heart, in which the muscular coat is the most developed. ===I. The Blood Vessels=== A. Capillaries. Their diameter varies between 7 and iop. They form extensive networks whose meshes vary in size in the different organs. ...
Pain is the most prominent symptom of Fibromyalgia. It usually affects the entire body, although it may start in one area, such as the neck and shoulders, and spread to other areas over a period of time. Fibromyalgia is a form of generalized muscular pain and fatigue. The name, Fibromyalgia, means pain in the muscles and the fibrous connective tissues (the ligaments and tendons).. You (or someone you know) may be experiencing moderate or severe fatigue with a lack of energy, decreased exercise endurance, or the kind of exhaustion that results from the flu or lack of sleep. Sometimes the fatigue is more of a problem than the pain. Headaches, especially tension and migraine headaches, are common in Fibromyalgia. Abdominal pain, bloating, alternating constipation, bladder spasms, and irritability may cause urinary urgency or frequency. Your skin and blood circulation can be sensitive to temperature changes, resulting in temporary changes in skin color.. Have you suffered with for a few months, a ...
INTRODUCTION. Muscle fibers and extracellular intramuscular connective tissue are the main components of skeletal striated muscle. In order to identify types of fibers, the enzymatic activity is one of the characteristics that had permitted to classify myocytes according to their metabolism (oxidative, intermediate and glycolytic), velocity of contraction (slow twitch fibers, intermediate fibers and fast twitch fibers) and to molecular level, isoforms of myosin heavy chain (MHC-1, MHC-IIA, MCHIIB) (Purslow, 2010; de Freitas et al., 2009; Scott et al., 2001). Enzyme histochemistry techniques such as mATPase (myosin adenosine triphosphatase) and NADH-TR (nicotinamide adenine dinucleotide tetrazolium reductase), indicate in striated skeletal muscle tissue, fast twitch fibers that are associated with glycolytic and glycolytic-intermediate metabolism, while slow twitch fibers with oxidative metabolism (Vivo et al., 2004; Hebling et al., 2006; Carmo-Araújo et al., 2007; de Freitas et al.).. Modern ...
Fibrosarcoma (fibroblastic sarcoma) is a malignant mesenchymal tumour derived from fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. It is usually found in males aged 30 to 40. It ori
This medical illustration depicts cirrhosis of the liver. It emphasizes the increase in development of excess fibrous connective tissue in the liver.
Granulation tissue Granulation tissue is the perfused, fibrous connective tissue that replaces a fibrin clot in healing wounds. Granulation tissue typically
Not to be confused with Granuloma. Proud flesh redirects here. For other uses, see Proud Flesh (disambiguation). Granulation tissue is the perfused, fibrous connective tissue that replaces a fibrin clot in healing wounds. Granulation tissue…
People often make a mistake and believe that over shampooing or over ushing the hair can remedy the dandruff but it can actually be damaging to the hair. Does Dry Scalp Go Away On Its Own Dry Oily Roots Scalp and also hair falling. Acne dry skin hair that is pulled back into a For bacterial infections your physician may prescribe an antibiotic cream or pill. You can apply gram flour and curd as a home remedy to treat dandruff at home. There are many tried and tested psoriasis home remedies which one should try before even jumping to highly expensive medications. Goldwell Dualsenses Scalp Specialist Anti Dandruff 250 ml.. Inflammation of the outer skin and middle (muscle connective tissue and glands) portions of the eyelids is medically referred to as blepharitis. 1000s of Toy drones in stock. T Gel Daily curd and egg for dandruff zinc anti shampoo pureology scalpcure pyrithione Control 2 in 1 Dandruff Shampoo Plus Conditioner See ingredient review and recommendation. If so its likely not ...
Administration of triamcinolone diacetate to rats results in a decrease of prolyl hydroxylase activity in organs from animals of different ages. The response of the enzyme activity is dose-dependent, reversible, independent of endocrine function (except for the response of the liver enzyme in hypophysectomized rats), and dependent on the number of daily injections. The decrease in enzyme activity is paralleled by a decrease in the amount of enzyme protein as measured by immunoassay. These results indicate that prolyl hydroxylase is decreased in a wide spectrum of tissues following administration of anti-inflammatory steroids. Furthermore, these findings suggest that one of the effects of this class of therapeutically used drugs on connective tissue metabolism may be mediated by a decrease in the prolyl hydroxylation step of collagen biosynthesis.. ...
Men and women possess a different connective tissue structure at the first layer of subcutaneous fat. The adipose tissue in females is contained in chamber-like structures that supports the expansion of the adipose tissue into the dermis. On the contrary, mens connective tissue architecture is criss-cross which allow for the subcutaneous fat to expand laterally and internally with little to no protrusion into the dermis. Men also have a thicker epidermis and dermis tissue layers in the thighs and buttocks. Hormone variations can differ between genders and according to some researchers, can cause subcutaneous fat cell appearance similar to females in men who are born deficient in male hormones. See more on The Cellulite Solution: A Doctors Program for Losing Lumps, Bumps, Dimples, and Stretch Marks.. ...
The following is taken verbatim from a hand-out at the World Conference on Breast Cancer.. Breast Cancer: Prevent and Survive it with Iodine. Presentation by David M. Derry, MD, PhD. Dr. Derry believes that breast cancer can be treated effectively. He will discuss:. What causes breast cancer. How cancer spreads. How thyroid hormones strengthen the connective tissue cancer barrier. How adequate iodine intake can reduce breast cancer to a controllable chronic disease of little significance. Hypothesis:. Cancer development has two phases - one controlled by iodine, and the other by thyroid hormone. Using this two-phase hypothesis, we can better understand fibrocystic disease and breast cancer. Supplemental iodine in correct doses triggers apoptosis or natural cell death, which destroys abnormal cells that are in the process of becoming cancer cells, and even kills some early cancer cells. Adequate thyroid hormone blocks cancer cells from spreading through connective tissue.. With optimum amounts ...
When people hear about the idea of stressing joints, their hackles go up. They worry about overstretching dense connective tissues and ligaments. Ive noticed that this fear often comes from confusing stress with stretch. Stressis force applied to something, in this case our joint tissue. Stretch is the subsequent lengthening that occurs due to the stress placed on that tissue. But not all stress causes stretch. And in Yin Yoga, the intention is to safely and moderately stress our joints to promote the health of the tissues in and around our joints - not to overly lengthen these tissues. In Yin Yoga, great care is given to observing the kinds of sensations one experiences, emphasizing the mild end of the sensation spectrum - not pushing, pulling, or striving to go deeper, and always avoiding any signal of pain. Practiced intelligently, Yin Yoga is a tissue-specific exercise, and shouldnt be approached with the mindset of more is better. Of course, as with any yoga style, people might ...
Terminal pad - Lies at anterior end of club (i.e., distal to the dactylus (when present)); consists of 1-20 or so, smooth ringed suckers. All suckers are often tightly packed together in an oval or slightly elongate shape and have short, approximately equal-sized stalks. A flap of skin curves over the distal edges of the pad. The aboral side of the pad contains what appears to be a thick dermis of dense connective tissue not found elsewhere on the club. The function of the terminal pad as a distal locking-mechanism is known, from experimental evidence, only in loliginids (loliginids lack a carpus): As the tentacles elongate, they twist so that the suckers face outward and the tips of the clubs remain attached (Keir and van Leeuwen, 1997, an experimental analysis of Loligo pealei attacking a tethered shrimp). In oegopsids the terminal pad seems to act as a distal locking-mechanism to help hold the clubs together, at least, when not in use (see photographs below). The locking mechanism differs ...
Parasitol, foxia Dense connective tissue plate in each eyelid Contains meibomian glands 29 mm long and 1 augmentin allergy ancef thick; tapered at ends Rigid attachments to eriosteummediall laterally пппFigure 6-14.
Connective tissue is the material that supports the organs in your body. It gives your tissues shape and strength. There are over 200 disorders that affect connective tissue. Together, they are known as connective tissue disorders, or CTDs.
Collagens are the fundamental structural proteins in vertebrates, where they fulfill a variety of critical roles in connective tissue structure and mechanics. As such, alterations in collagens composition, resulting from genetic modifications, aging, and diabetes, have been identified with an extensive list of diseases [1, 2]. Additionally, due to their natural role as the structural component in the extracellular matrix, collagens have found widespread use in biomaterials, used for cellular and tissue engineering, drug delivery, and a wide range of other applications [3-5].. Most studies on collagens use protein extracted from animal tissues. While this provides a large-scale supply of the protein, the lack of control over protein composition has its drawbacks. For example, there is minimal ability to select protein sequence, since generally type I collagen is most easy to extract and its sequence varies little among different animal species. Furthermore, because posttranslational ...
Tendinitis Tendinitis is inflammation of a tendon-the flexible connective tissue structures that connect your muscles to your bones. Inflammation is the localized response by your body to injury or damage caused by chemical, physical, or biological agents. Most tendinitis treated by podiatrists and other healthcare providers is caused by tendon overuse, most commonly associated with athletic endeavors. Tendinitis in your feet and lower extremities can significantly impair your ability to perform your activities of daily living ...
A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis. - National Library of Medicine Medical Subject Headings 2000
Although a few pathogens cause most surgical infections, many organisms are capable of doing so. Among the aerobic organisms, streptococci may invade even minor breaks in the skin and spread through connective tissue planes and lymphatics. Staphylococcus aureus is the most common pathogen in wound infections and around foreign bodies. Klebsiella often invades the inner ear and enteric tissues as well as the lung. Enteric organisms, especially the Enterobacteriaceae and enterococci, are often found together with anaerobes. Among the anaerobes, bacteroides species and Peptostreptococci are often present in surgical infections, and clostridium species are major pathogens in ischemic tissue. ...
Connective tissue gives shape to organs and holds them in place. The main types are loose connective tissue, adipose tissue, ... Connective tissue[edit]. Connective tissues are fibrous and made up of cells scattered among inorganic material called the ... Animal tissues can be grouped into four basic types: connective, epithelial, muscle and nervous tissue. ... The most basic types of metazoan tissues are epithelium and connective tissue, both of which are present in nearly all ...
Connective tissue disorders[edit]. Arthritis[edit]. Some instance of arthritis with small bowel villous atrophy have been found ... and anti-connective tissue antibodies have been found in increased levels in celiac disease.[93] Anti-rheumatoid factor ... RCD 2 involves neoplastic tissues that the lack of surface expression of usual T-cell markers.[109] *Increased expression of: ... RCD 1 involves precancerous tissues in which transformed T-cells continue to produce a response even though gluten is no longer ...
Loose connective tissue[edit]. Loose connective tissue contains fibres, extracellular matrix, cells, nerves and blood vessels. ... dynamic group of tissues. The alveolar bone (C) is surrounded for the most part by the subepithelial connective tissue of the ... The periodontal ligament, commonly abbreviated as the PDL, is a group of specialized connective tissue fibers that essentially ... The PDL consists of principal fibres, loose connective tissue, blast and clast cells, oxytalan fibres and Cell Rest of Malassez ...
Connective tissues[edit]. OI causes very thin blood vessels and may also result in people being bruised easily. The weakening ... The underlying mechanism is usually a problem with connective tissue due to a lack of type I collagen.[1] This occurs in more ... People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of ... Grond-Ginsbach, C; Debette, S (March 2009). "The association of connective tissue disorders with cervical artery dissections". ...
M: Diseases of the musculoskeletal system and connective tissue[edit]. *(M25.1) Fistula of joint ... The tissues die and a hole forms through which urine and/or feces pass uncontrollably. Vesicovaginal and rectovaginal fistulas ... An obstetric fistula develops when blood supply to the tissues of the vagina and the bladder (and/or rectum) is cut off during ... where healthy tissue is pulled over the internal side of the fistula to keep feces or other material from reinfecting the ...
Dense irregular connective tissue *Submucosa. *Dermis. *Dense regular connective tissue *Ligament. *Tendon ...
Mesodermal tissue will continue to differentiate and/or migrate throughout the embryo to ultimately form most connective tissue ... undifferentiated tissue found in embryonic true mesoderm - entomesoderm - from which all connective tissues like blood vessels ... Mesenchyme, in vertebrate embryology, is a type of connective tissue found mostly during the development of the embryo.[1] It ... This latter system is characterized as connective tissues throughout the body, such as bone, muscle and cartilage. A malignant ...
TermsCells&Tissues/connective/elastic/elastic2 - Comparative Organology at University of California, Davis - "Connective tissue ... Elastic tissue is classified as "connective tissue proper".[2] The elastic fiber is formed from the elastic microfibril ( ... connective tissue proper, elastic cartilage, periodontal ligament, fetal tissue and other structures. Elastic fibers are absent ... Elastic fibers (or yellow fibers) are bundles of proteins (elastin) found in extracellular matrix[1] of connective tissue and ...
Each type of connective tissue in animals has a type of ECM: collagen fibers and bone mineral comprise the ECM of bone tissue; ... Fibroblasts are the most common cell type in connective tissue ECM, in which they synthesize, maintain, and provide a ... The ECM can exist in varying degrees of stiffness and elasticity, from soft brain tissues to hard bone tissues. The elasticity ... Sound Medicine - Heart Tissue Regeneration - July 19 interview discussing ECM and its uses in cardiac tissue repair (requires ...
Marfan syndrome (MFS) is an autosomal dominant disorder that affects the connective tissues of bodily systems such as the eyes ... These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. ... The fragility of the connective tissue usually results in aortic aneurysms due to the wall having the inability to withstand ... and of distinct 8-cysteine modules to make up elastic and non-elastic tissue.[14][16] These elastic and non-elastic tissues are ...
A: Mucus gland, B: Chromatophore, C: Granular poison gland, D: Connective tissue, E: Stratum corneum, F: Transition zone, G: ... Adipose tissue is another important means of storing energy and this occurs in the abdomen (in internal structures called fat ... Damage to either of these areas can reduce the fitness of the rival, either because of the need to regenerate tissue or because ... Specific events are dependent on threshold values for different tissues.[76] Because most embryonic development is outside the ...
Connective and. vascular. *see Template:Soft tissue tumors and sarcomas, Template:Vascular tumors, Template:Myeloid malignancy ... Connective/soft tissue tumors and sarcomas (ICD-O 8800-9059) (C45-C49/D17-D21, 171/214-215) ...
Connective/soft tissue tumors and sarcomas (ICD-O 8800-9059) (C45-C49/D17-D21, 171/214-215) ... In obstetrics and gynecology contexts, it is a form of adenomyosis that forms a mass or growth around the tissue of the inner ...
... adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue). Weight loss can ... Connective tissue disease. *Oral, taste or dental problems (including infections) can reduce nutrient intake leading to weight ...
Boskey, A.L. (2003). "Biomineralization: An overview". Connective Tissue Research. 44 (Supplement 1): 5-9. doi:10.1080/ ... Such tissues are called mineralized tissues. It is an extremely widespread phenomenon; all six taxonomic kingdoms contain ... Biomineralization is the process by which living organisms produce minerals,[a][2] often to harden or stiffen existing tissues ... Onozato, Hiroshi (1979). "Studies on fish scale formation and resorption". Cell and Tissue Research. 201 (3): 409-422. doi: ...
Boskey AL (2003). "Biomineralization: an overview". Connective Tissue Research. 44 Suppl 1 (1): 5-9. doi:10.1080/713713622. ... produced by epithelial tissues in most animals.[1] Mucins' key characteristic is their ability to form gels; therefore they are ... colon and other tissues. Mucins are also overexpressed in lung diseases such as asthma, bronchitis, chronic obstructive ...
Connective Tissue Research. 44 (Suppl. 1): 41-46. doi:10.1080/03008200390152070. PMID 12952172. S2CID 2249126.. ...
... body fat or adipose tissue or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue. Weight loss ...
Connective tissue research. 55 Suppl 1: 79-82. doi:10.3109/03008207.2014.923864. PMID 25158186.. .mw-parser-output cite. ... "Extracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to ...
Connective/soft tissue tumors and sarcomas (ICD-O 8800-9059) (C45-C49/D17-D21, 171/214-215) ...
... collagenous connective tissue that covers, invests, and forms the terminations of the muscles. ... using intranasal tissues to correct defects of the mucosa; cartilage battens to brace against tissue contraction and depression ... the sesamoid cartilages are adjacent to the upper lateral-cartilages in the fibroareolar connective tissue. ... usually with a regional tissue graft, harvested from either the face or the head, or with a tissue graft harvested from ...
In addition to SLE, these antibodies are highly associated with mixed connective tissue disease. Anti-nRNP antibodies recognise ... A significant number of patients are diagnosed as systemic lupus erythematosus or undifferentiated connective tissue disease ... mixed connective tissue disease,[5] polymyositis, dermatomyositis, autoimmune hepatitis[6] and drug induced lupus.[7] ... "Mixed connective tissue disease". Lupus. 15 (3): 132-7. doi:10.1191/0961203306lu2283rr. PMID 16634365. S2CID 25736411.. ...
Desmoplasia (connective tissue growth). *Atrophy (reduced functionality of an organ, with decrease in the number or volume of ... Pathologic atrophy of muscles can occur with diseases of the motor nerves or diseases of the muscle tissue itself. Examples of ... Atrophy is reduction in size of cell, organ or tissue, after attaining its normal mature growth. In contrast, hypoplasia is the ... Atrophy is the general physiological process of reabsorption and breakdown of tissues, involving apoptosis. When it occurs as a ...
It consists of loose connective tissue, adipose tissue and elastin. The main cell types are fibroblasts, macrophages and ... Oikarinen, A. (2004). "Connective tissue and aging". International Journal of Cosmetic Science. 26 (2): 107. doi:10.1111/j.1467 ... Subcutaneous tissue[edit]. The subcutaneous tissue (also hypodermis and subcutis) is not part of the skin, but lies below the ... The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and ...
Systemic connective tissue disorders. *Drug-induced diseases. Hidden categories: *All articles with unsourced statements ... Serositis-inflammation of the tissues lining the heart and lungs.. *Anti-histone antibodies in 95% of cases among those taking ...
connective tissue, lungs, eye blood (Giemsa, haematoxylin, eosin stain) rain forest of West Africa - 12-13 million people ... dead or living tissue Screwworm, Cochliomyia Cochliomyia hominivorax (family Calliphoridae) skin and wounds visual North ... Subcutaneous tissue physical examination Central and South America, Sub-Saharan Africa Human botfly Dermatobia hominis ... skin, eye, tissue bloodless skin snip Africa, Yemen, Central and South America near cool, fast flowing rivers Simulium/black ...
Mixed connective tissue disease, systemic lupus erythematosus, polymyositis, dermatomyositis[1]. Treatment. Supportive care[1] ... Group of autoimmune diseases resulting in abnormal growth of connective tissue. This article is about the disease. For the ... Eosinophilic fasciitis affects the connective tissue surrounding skeletal muscles, bones, blood vessels, and nerves in the arms ... and production of altered connective tissue.[19] Its proposed pathogenesis is the following:[20][21][22][23][24] ...
Desmoplasia (connective tissue growth). *Atrophy (reduced functionality of an organ, with decrease in the number or volume of ... Focal epithelial hyperplasia (also known as Heck's disease) - This is a wart-like growth in the mucous tissues of the mouth or ... Abiotrophy (loss in vitality of organ or tissue). *Dystrophy (any degenerative disorder resulting from improper or faulty ... is an increase in the amount of organic tissue that results from cell proliferation.[4] It may lead to the gross enlargement of ...
Desmoplasia (connective tissue growth). *Atrophy (reduced functionality of an organ, with decrease in the number or volume of ... within a breast cancer tissue sample is about 20,000.[57] In an average melanoma tissue sample (where melanomas have a higher ... Neoplasm is an abnormal growth of tissue which, if it forms a mass, is commonly referred to as a tumor.[1][2][3] This abnormal ... Volokh KY (September 2006). "Stresses in growing soft tissues". Acta Biomater. 2 (5): 493-504. doi:10.1016/j.actbio.2006.04.002 ...
Desmoplasia (connective tissue growth). *Dysplasia (change in cell or tissue phenotype). *Hyperplasia (proliferation of cells) ... The following table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the change: Tissue ... Abiotrophy (loss in vitality of organ or tissue). *Atrophy (reduced functionality of an organ, with decrease in the number or ... Hypotrophy (decrease in the volume of cells or tissues). *Dystrophy (any degenerative disorder resulting from improper or ...
Connective tissue cells. Hidden categories: *All articles with unsourced statements. *Articles with unsourced statements from ...
நார்ப்புரதம், உடல்தசைகளில் உள்ள இணைப்புத் திசுககளிலும் (connective tissues), குருத்தெலும்பிலும், எலும்பின் உள்கட்டமைப்பிலும், ...
... skin discoloration and connective tissue damage from the accumulation of homogentisic acid).[35] ... the follicle can break into the deeper layers of the dermis and subcutaneous tissue and cause the formation of deep nodules.[1] ... whereas keloid scars can form scar tissue outside of these borders.[32] Keloid scars from acne occur more often in men and ... which contribute to local tissue destruction and scar formation.[45] ...
Connective tissue disease. *Drugs-aspirin, fexofenadine, warfarin, clopidogrel, prasugrel, isotretinoin, desmopressin and ...
The skin consists of a thin outer epidermis with mucous cells and sensory cells, and a connective tissue dermis consisting ... Extensive connective tissue lattices support the respiratory muscles and allow them to expand the respiratory chamber.[37] The ... Once the shell is penetrated, the prey dies almost instantaneously, its muscles relax, and the soft tissues are easy for the ... Octopuses are mostly soft tissue, and so fossils are relatively rare. Octopuses, squids and cuttlefish belong to the clade ...
... before any genetic or morphological criteria were put in place for bone marrow or connective tissues. Osteoprogenitor cells can ... These cellular units will then develop into skeletal and other tissues, such as cartilage, tendon, ligament and muscle tissue. ... Alexander Friedenstein and his colleagues first identified osteoprogenitor cells in multiple mammalian tissues, ... Tissue Eng Part A. 14 (9): 1573-80. doi:10.1089/ten.tea.2008.0113. PMID 18774911.. ...
Connective tissue growth factor (CTGF). *Ephrins (A1, A2, A3, A4, A5, B1, B2, B3) ...
... and special connective tissue.[5][6] Connective tissue proper consists of loose connective tissue and dense connective tissue ( ... Connective tissue (CT) is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and ... Special connective tissue consists of reticular connective tissue, adipose tissue, cartilage, bone, and blood.[8] Other kinds ... Staining of connective tissueEdit. For microscopic viewing, most of the connective tissue staining-techniques, colour tissue ...
Human brains are surrounded by a system of connective tissue membranes called meninges that separate the brain from the skull. ... in the sense that the neoplasm invades the space occupied by adjacent tissue, thereby pushing the other tissue aside and ... they will expand spatially and intrude into the space occupied by other brain tissue and compress those brain tissues); however ... Living brain tissue has a pink tint in color on the outside (gray matter), and nearly complete white on the inside (white ...
... which breaks down the connective tissue fiber elastin. Like all serine protease inhibitors, A1AT has a characteristic secondary ... As a type of enzyme inhibitor, it protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has ... This causes the degradation especially of lung tissue and eventually leads to characteristic manifestations of pulmonary ... an autosomal codominant hereditary disorder in which a deficiency of alpha-1 antitrypsin leads to a chronic uninhibited tissue ...
... a major constituent of extracellular microfibrils which form connective tissues.[36] Over 1,000 different mutations in FBN1 ... which consequently relates to connective tissues elongating progressively and weakening. Because these fibers are found in ... An example is the p53 gene, which suppresses cancer but also suppresses stem cells, which replenish worn-out tissue.[13] ... those chickens who express higher levels of these two genes in bone tissue produce more eggs and display less egg incubation ...
... via connective tissue) to the rest of the viscera. By using a series of special muscles (roughly equivalent to a diaphragm), ... Morphological and cellular aspects of tail and limb regeneration in lizards a model system with implications for tissue ...
Hypermobility syndrome is genetically inherited disorder that is thought to affect the encoding of the connective tissue ... Reduction should only be performed by trained medical professionals, because it can cause injury to soft tissue and/or the ... for a more detailed inspection of the joint-supporting structures in order to assess for ligamentous and other soft tissue ...
... or other connective or supportive tissue. Low-grade refers to cancerous and precancerous growths with cells that look nearly ... The mucus may come from ruptured ovarian cysts, the appendix, or from other abdominal tissues, and mucus-secreting cells may ... Ovarian Carcinoma: Cancer that forms in tissues of the ovary. Most ovarian cancers are either ovarian epithelial carcinomas ( ...
Tunica adventitia:為疏鬆結締組織(loose connective tissue),有纖維母細胞分泌胞外基質,還有巨噬細胞在此。由
... s have a capsule of connective tissue, and run parallel to the extrafusal muscle fibers.[c] ...
... teeth and connective tissues - Aids the production of collagen which is the foundational matrix of bones, teeth, tendons, ... connective tissue and cartilage. Vitamin A ensures sufficient collagen is produced to build strong healthy bones and other ... Vitamin A assists in the maintenance and promotion of healthy growth of skin and tissues cells. Healthy growth of tissue cells ... Maintains mucous cell tissues to ensure a secure barrier against harmful bacteria's and disease (Deen & Hark, 2007) Helps ...
... connective tissue disease), ହାଇପୋଥାଇରଏଡିଜ୍ମ, ଆଓର୍ଟିକ ରପଚର (aortic rupture) ଓ ହୃତ୍‌ପିଣ୍ଡ ଅପରେଶନ (cardiac surgery) ପରେ ଏହି ରୋଗ ...
It also makes blood vessels more permeable so neutrophils and clotting proteins can get into connective tissue more easily. ... Monocytes migrate from the bloodstream to other tissues and differentiate into tissue resident macrophages, Kupffer cells in ... Some leucocytes migrate into the tissues of the body to take up a permanent residence at that location rather than remaining in ... Often these cells have specific names depending upon which tissue they settle in, such as fixed macrophages in the liver, which ...
The destruction of the connective tissue of the lungs leads to emphysema, which then contributes to the poor airflow, and ... and breakdown of the connective tissue of the lungs by proteases that are insufficiently inhibited by protease inhibitors. ... For the abnormal occurrence of gas within tissue, see pneumatosis. For the long-term productive cough, see Bronchitis § Chronic ... Micrograph showing emphysema (left - large empty spaces) and lung tissue with relative preservation of the alveoli (right) ...
The biochemistry of Hunter syndrome is related to a problem in a part of the connective tissue of the body known as the ... As a result, GAGs build up in cells throughout the body, particularly in tissues that contain large amounts of dermatan sulfate ... Prenatal diagnosis is routinely available by measuring I2S enzymatic activity in amniotic fluid or in chorionic villus tissue. ...
Systemic connective tissue disorders (M32-M36, 710). General. Systemic lupus erythematosus. *Drug-induced SLE ...
Diseases of the skin and subcutaneous tissue XIII M00-M99 Diseases of the musculoskeletal system and connective tissue ...
Connective tissue growth factor (CTGF). *Ephrins (A1, A2, A3, A4, A5, B1, B2, B3) ... Although BDNF is needed in the developmental stages, BDNF levels have been shown to decrease in tissues with aging.[90] Studies ... The Val66Met mutation results in a reduction of hippocampal tissue and has since been reported in a high number of individuals ... Post mortem analysis has shown lowered levels of BDNF in the brain tissues of people with Alzheimer's disease, although the ...
The influence of isotretinoin and 5-a reductase inhibitors in metaloproteases of connective tissue in patients with ance] (in ... the tissue inhibitors of metalloproteases).[69] It is already known that metalloproteases play an important role in the ...
Mast cells are a type of innate immune cell in connective tissue and the mucous membranes. They are intimately associated with ... It sets up a physical barrier against the spread of infection, and promotes healing of damaged tissue after the clearance of ... Dendritic cells (DC) are phagocytic cells present in tissues that are in contact with the external environment, mainly the skin ... Phagocytosis of the hosts' own cells is common as part of regular tissue development and maintenance. When host cells die, ...
Mast cells are a type of innate immune cell that reside in connective tissue and in the mucous membranes. They are intimately ... swelling of affected tissues, such as the upper throat during the common cold or joints affected by rheumatoid arthritis; ... Most leukocytes differ from other cells of the body in that they are not tightly associated with a particular organ or tissue; ... In tissues, organ-specific macrophages are differentiated from phagocytic cells present in the blood called monocytes. ...
Hence, knowledge is the catalyst and connective tissue in modern economies. With Earth's depleting natural resources, the need ...
adipose tissue. A type of loose connective tissue made of mostly adipocytes and found in human and animal tissue, where it is ... The fibrous connective tissue that connects bones to other bones and is also known as articular ligament, articular larua, ... A cell filled with basophil granules, found in numbers in connective tissue and releasing histamine and other substances during ... tissue. trait. transcription. The first step of gene expression, in which a particular segment of DNA is copied into RNA by the ...
... and special connective tissue.[6][7] Connective tissue proper consists of loose connective tissue and dense connective tissue ( ... Connective tissue (CT) is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and ... Special connective tissue consists of reticular connective tissue, adipose tissue, cartilage, bone, and blood.[9] Other kinds ... Loose and dense connective tissue are distinguished by the ratio of ground substance to fibrous tissue. Loose connective tissue ...
... cules of animal connective tissues. It attempts to answer some general questions about the biological organization of the ... In doing so, however, I have treated cursorily many important aspects of connective tissue biology that appeared to be only ... This book deals primarily with the principal extracellular macromole- cules of animal connective tissues. It attempts to answer ... Bindegewebe Molekularbiologie biology invertebrates molecular biology tissue vertebrates Authors and affiliations. *Martin B. ...
"Mixed Connective Tissue Disease, MCTD". The Free Dictionary by Farlex.. *^ Nevares AM, Larner R. "Mixed Connective Tissue ... "Mixed Connective Tissue Disease (MCTD)". MedicineNet.com.. *. Nevares AM, Larner R. "Mixed Connective Tissue Disease (MCTD): ... "Mixed Connective Tissue Disease (MCTD)". NORD (National Organization for Rare Disorders). Retrieved 2019-10-12.. ... "Prognosis and treatment of mixed connective tissue disease".. *^ Yang, Chia‐Fu; Chiu, Jih‐Yu; Su, Chang‐Wei; Chen, Chun‐Ming ( ...
Tissue General structure of connective tissue Overview of connective tissue matrix Types of connective tissue Connective tissue ... composed of ground substance and protein fibers Mostly fluid connective tissue Source for information on Connective Tissue: The ... Loose connective tissue has fewer collagen fibers than dense connective tissue; it therefore is not as tough. Loose connective ... Overview of connective tissue matrix. Of the three types of protein fibers in connective tissue, collagen is by far the most ...
Connective tissue - Cartilage: Cartilage is a form of connective tissue in which the ground substance is abundant and of a ... firmly gelated consistency that endows this tissue with unusual rigidity and resistance to compression. The cells of cartilage ... meat processing: Connective tissue. The amount of connective tissue in a muscle has a complex effect on the tenderness of the ... skeleton: Connective tissue. Below the ectoderm of many animals, connective tissue forms sheets of varying complexity, existing ...
Connective and Skeletal Tissue. Br Med J 1966; 1 doi: https://doi.org/10.1136/bmj.1.5493.968-a (Published 16 April 1966) Cite ...
Words related to connective tissue:. = 48 && event.charCode <= 57 value="Num letters..." onfocus="inputFocus(this)" onblur=" ...
Purchase International Review of Connective Tissue Research - 1st Edition. Print Book & E-Book. ISBN 9781483167510, ... Components of Connective Tissues. III. The Connective Tissues of the Reproductive Tract. IV. The Uterus. V. Connective Tissues ... Morbid Anatomy of Connective Tissue Injury. IV. An Etiological Classification of Diseases of Connective Tissue. V. Connective ... I. Constituents of Connective Tissue. II. The Concept of Collagen or Connective Tissue Disease. III. ...
Purchase International Review of Connective Tissue Research - 1st Edition. Print Book & E-Book. ISBN 9781483167541, ... The Connective Tissues in Copper Deficiency. IV. Biogenesis of Connective Tissues. V. Relation of Copper to Connective Tissue ... International Review of Connective Tissue Research covers a broad range of aspects of connective tissue metabolism and ... effect of ionizing radiation on connective tissue components; and the physical properties of connective tissue. Physiologists, ...
Get information on mixed connective tissue disease (MCTD) symptoms, types, treatment, and prognosis. MCTD is an overlap of ... Connective tissues are the framework of the cells of the body.. *Mixed connective tissue disease is considered an overlap of ... What are causes and risk factors for mixed connective tissue disease?. *What are signs and symptoms of mixed connective tissue ... Other diseases of connective tissue do not have specific gene abnormalities as their sole cause. These connective tissue ...
... and special connective tissue.[5][6] Connective tissue proper consists of loose connective tissue and dense connective tissue ( ... Connective tissue (CT) is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and ... Special connective tissue consists of reticular connective tissue, adipose tissue, cartilage, bone, and blood.[8] Other kinds ... Staining of connective tissueEdit. For microscopic viewing, most of the connective tissue staining-techniques, colour tissue ...
What do you guys know about ways to strengthen connective tissue? I have various problems, including a partially torn triceps ... Connective Tissue Strengthening What do you guys know about ways to strengthen connective tissue? I have various problems, ... Connective Tissue Strengthening. Welcome to the EliteFitness.com Bodybuilding Site! Please join this discussion about ... Excerpt: What do you guys know about ways to strengthen connective tissue? I have various problems, including a partially torn ...
Connective tissue can be broadly classified into connective tissue proper and special connective tissue.[5][6] Connective ... Connective tissue is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and nervous ... Special connective tissue consists of reticular connective tissue, adipose tissue, cartilage, bone, and blood.[8] Other kinds ... and lymphoid connective tissues.[9] Fibroareolar tissue is a mix of fibrous and areolar tissue.[10] Fibromuscular tissue is ...
... has added 12 new assays to its menu of molecular diagnostics for inherited disorders affecting connective tissues. ... Connective Tissue Gene Tests (CTGT) has added 12 new assays to its menu of molecular diagnostics for inherited disorders ... affecting connective tissues. The Allentown, Pa.-based company is now offering microarray, Sanger sequencing, and next- ... A Comprehensive Strategy for Evaluating NGS Liquid Biopsy and Tumor Tissue Assays. ...
... for repairing injured connective tissue. These systems may include, among others, a surgical stapler and staples for repairing ... The injured connective tissue may be a tendon, a ligament, and/or any other suitable type of connective tissue. The term " ... The connective tissue repair apparatus of claim 1. , the connective tissue being severed, forming first and second severed ends ... The connective tissue repair apparatus of claim 1. , further comprising a connective tissue clamp operatively connected to the ...
Age-related changes in skeletal muscle support the idea that the interaction between contractile and connective tissues is ... Mechanical adaptability of sea cucumber Cuvierian tubules involves a mutable collagenous tissue Mélanie Demeuldre, Elise ... Summary: Sea cucumber Cuvierian tubules are a remarkable defence system with characteristics of mutable collagenous tissues, ...
... the Connective Tissue Motion Measure - capable of documenting and monitoring the functional status of human connective tissues ... the Connective Tissue Motion Measure (CTMM) - quantifying the functional behavior of perimuscular connective tissues. The ... It is anticipated that this technology will establish the usefulness of connective tissue motion measurements for the diagnosis ... differential motion between specific connective tissue strata will be measured during tissue displacement (linear oscillation) ...
Connective tissue diseases are autoimmune diseases. They include systemic lupus, scleroderma, polymyositis, dermatomyositis, ... A connective tissue disease is any disease that has the connective tissues of the body as a primary target of pathology. The ... A common symptom of connective tissue (CT) disease is nonspecific fatigue. Depending on which connective tissue disease is ... These tissues form a framework, or matrix, for the body. The connective tissues are composed of two major structural protein ...
Connective tissue can be broadly classified into connective tissue proper and special connective tissue. Connective tissue ... Connective tissue is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and nervous ... Fibromuscular tissue is made up of fibrous tissue and muscular tissue. New vascularised connective tissue that forms in the ... Other kinds of connective tissues include fibrous, elastic, and lymphoid connective tissues. Fibroareolar tissue is a mix of ...
Reticular connective tissue is a type of body tissue that is supported with a branching framework of collagen fibers. It is ... The tissue is similar to connective tissue with a high amount of elastic fibers, except that in reticular connective tissue, ... Reticular connective tissue is a type of tissue found in the body that is supported with a branching framework of collagen ... These fibers are present in many types of connective tissue and are particularly heavily concentrated in this tissue. Some ...
Fibrous connective tissue is a body tissue made of high-strength, slightly stretchy fibers. The main role of fibrous connective ... they are sometimes simply referred to as dense connective tissues.. Connective tissue is one of the four main kinds of tissue ... Fibrous connective tissue, sometimes referred to as FCT, is tissue made up of high-strength, slightly stretchy fibers. These ... There are many kinds of connective tissue in the body, and many of these tissues contain the fibrous strands of the protein ...
Loose Connective Tissue and Organs (uterus, liver,spleen,kidney, lung, etc) smooth muscle, endonerium, blood vessels, and fetal ...
A connective tissue nevus may be present at birth or appear within the first few years, is elevated, soft to firm, varying from ...
This set of 4 slides is designed to aid your study of connective tissue histology. Represented are compact bone, tendon, and ... This set of 4 slides is designed to aid your study of connective tissue histology. Represented are compact bone, tendon, and ... Begin your study of connective tissues with this unique set of 4 slides with self-study cards! A representative histology slide ... Carolinas innovative, proprietary tissue fixative produces superior specimens with life-like tissue texture and color. ...
... counselling and treatment to Albertans across the lifespan who are at risk for or affected with connective tissues disorders. ... Genetic Connective Tissues Disorders Clinic. Provides genetic assessment, screening, diagnosis, counselling and treatment to ... Examples of connective tissue disorders include Marfan syndrome, Ehlers-Danlos syndrome, Stickler syndrome, and many others. ... This service is available to individuals who are affected or at moderate to high risk for inherited connective tissue disorders ...
... Aroj Bhattarai and Manfred Staat ... Aroj Bhattarai and Manfred Staat, "Modelling of Soft Connective Tissues to Investigate Female Pelvic Floor Dysfunctions," ...
... on WN Network delivers the latest Videos and Editable pages for News & Events, including Entertainment, Music ... Connective tissue can be broadly subdivided into connective tissue proper, and special connective tissue.Connective tissue ... Connective tissue can be broadly subdivided into connective tissue proper, and special connective tissue.Connective tissue ... Connective tissue. Connective tissue (CT) is one of the four types of biological tissue that support, connect, or separate ...
Connective Tissue by Medical Professionals (eBook) online at Lulu. Visit the Lulu Marketplace for product details, ratings, and ... Connective tissue is a fibrous and most diverse tissue. It is one of the four traditional classes of tissues (the others being ... form the pliable connective tissue as a whole. Connective tissue makes up a variety of physical structures including tendons ... Complete Medical Guide for Disease Volume IX: Connective Tissue By Medical Professionals & National Institute of Health ...
Tissue Vector Art, Graphics and Stock Illustrations. Download 53 Royalty Free Connective & Tissue Vector Images. ... Connective tissue vector * Connective tissue from a lymphatic gland vintage vector * Joints and connective tissues and back ... Connective tissue vintage vector * Branched connective tissue corpuscles vintage vector * Muscle innervation connective tissue ... Connective tissue cells from a frog vintage vector * ... Connective tissue vintage vector * Connective tissue icons set ...
  • Special connective tissue consists of reticular connective tissue , adipose tissue , cartilage , bone , and blood . (wikipedia.org)
  • Connective tissue is found throughout the body and includes fat, cartilage, bone, and blood. (encyclopedia.com)
  • Two main types of this kind of connective tissue are found in the body: cartilage and bone. (encyclopedia.com)
  • Cartilage is a form of connective tissue in which the ground substance is abundant and of a firmly gelated consistency that endows this tissue with unusual rigidity and resistance to compression. (britannica.com)
  • Some examples of connective tissue include the inner layers of skin, tendons , and ligaments , as well as cartilage , bone, fat tissue and even blood. (wisegeek.com)
  • Cartilage is the most commonly known form of fibrous connective tissue. (wisegeek.com)
  • The Connective Tissue Research Group, a Tennessee Center of Excellence, is a comprehensive center for basic clinical and translational research, education and training and community outreach for the State of Tennessee in diseases affecting the joints, cartilage, skeleton and connective tissues of the body. (uthsc.edu)
  • Bone & cartilage can also be grouped into supportive connective tissue. (wikipedia.org)
  • Various types of specialized tissues and cells are classified under the spectrum of connective tissue, and are as diverse as brown and white adipose tissue, blood, cartilage and bone. (wikipedia.org)
  • Connective tissue makes up a variety of physical structures including tendons and the connective framework of fibers in muscles, capsules and ligaments around joints, cartilage, bone, adipose tissue, blood and lymphatic tissue. (lulu.com)
  • This human anatomy ClipArt gallery offers 54 illustrations of human connective tissues, including fibrous connective tissue (e.g., ligaments, tendons), cartilage, osseous tissue, and adipose tissue. (usf.edu)
  • Fibrous cartilage connective tissue from the symphysis pubis, magnified. (usf.edu)
  • Bundles of white collagen fibres (containing the protein collagen ), strong and only slightly extensible, provide a supporting network in organs and tissues everywhere in the body (except the central nervous system) and in the sheaths and membranes that surround or separate them, form the basis of tendons and ligaments and are components of cartilage and bone . (thefreedictionary.com)
  • This micrograph shows hyaline cartilage, a semi-rigid connective tissue from a human trachea (windpipe). (thoughtco.com)
  • JOINT SUPPORT - Our joint support nutrition is scientifically formulated to restore flexibility and mobility while protecting and rebuilding your body's connective tissue, ligaments, cartilage, etc. (oxyfresh.com)
  • Cartilage is the soft tissue padding between all joints and bones which acts as a shock absorber. (xtend-life.com)
  • The connective tissues include several types of fibrous tissue that vary only in their density and cellularity, as well as the more specialized and recognizable variants-bone, ligaments, tendons, cartilage, and adipose (fat) tissue. (women.com)
  • Connective tissues include the bones, cartilage, tendons and fibrous tissue that support organs. (women.com)
  • Two examples of connective tissue are fat and cartilage. (opiates.com)
  • The five types of mature connective tissue are (1) loose connective tissue, (2) dense connective tissue, (3) cartilage, (4) bone tissue, and (5) liquid connective tissue. (majortests.com)
  • Heritable connective tissue disorders in humans are associated with many mutations that affect connective tissue proteins, including over 300 mutations affecting collagen, a protein substance found in skin, bone, cartilage, and all other connective tissues. (brightsurf.com)
  • Cartilage is a very rubbery tissue made by cells called chondroblasts. (sophia.org)
  • Chondroblasts are called chondrocytes after they are done producing the cartilage and are just sitting within the rubbery tissue. (sophia.org)
  • In cartilage cartilage , flexible semiopaque connective tissue without blood vessels or nerve cells. (thefreedictionary.com)
  • ligaments ligament , strong band of white fibrous connective tissue that joins bones to other bones or to cartilage in the joint areas. (thefreedictionary.com)
  • Bone and cartilage are special kinds of connective tissue. (thefreedictionary.com)
  • All connective tissue consists of three main components: fibers ( elastic and collagenous fibers ), [1] ground substance and cells . (wikipedia.org)
  • Dense regular connective tissue, found in structures such as tendons and ligaments , is characterized by collagen fibers arranged in an orderly parallel fashion, giving it tensile strength in one direction. (wikipedia.org)
  • Dense irregular connective tissue provides strength in multiple directions by its dense bundles of fibers arranged in all directions. (wikipedia.org)
  • [14] [15] Although there is no dense collagen network in adipose tissue, groups of adipose cells are kept together by collagen fibers and collagen sheets in order to keep fat tissue under compression in place (for example, the sole of the foot). (wikipedia.org)
  • Connective tissue has a wide variety of functions that depend on the types of cells and the different classes of fibers involved. (wikipedia.org)
  • Loose and dense irregular connective tissue , formed mainly by fibroblasts and collagen fibers , have an important role in providing a medium for oxygen and nutrients to diffuse from capillaries to cells, and carbon dioxide and waste substances to diffuse from cells back into circulation. (wikipedia.org)
  • Connective tissue is composed of living cells and protein fibers suspended in a gel-like material called matrix. (encyclopedia.com)
  • Depending on the type of connective tissue, the fibers are either collagen fibers, reticular fibers, elastin fibers, or a combination of two or more types. (encyclopedia.com)
  • The type and arrangement of the fibers gives each type of connective tissue its particular properties. (encyclopedia.com)
  • Of the three types of protein fibers in connective tissue, collagen is by far the most abundant, and accounts for almost one third of the total body weight of humans. (encyclopedia.com)
  • Elastin fibers have elastic properties and can stretch and be compressed, importing flexibility into the connective tissues where they are found. (encyclopedia.com)
  • In dense connective tissue, almost all the space between the cells is filled by large numbers of protein fibers. (encyclopedia.com)
  • In loose connective tissue, there are fewer fibers between the cells which imparts a more open, loose structure. (encyclopedia.com)
  • Dense connective tissue contains large numbers of collagen fibers, and so it is exceptionally tough. (encyclopedia.com)
  • Dense regular connective tissue has parallel bundles of collagen fibers and forms tendons that attach muscles to bone and ligaments that bind bone to bone. (encyclopedia.com)
  • Dense irregular connective tissue, with less orderly arranged collagen fibers, forms the tough lower layer of the skin known as the dermis and encapsulates delicate organs such as the kidneys and the spleen. (encyclopedia.com)
  • Reticular connective tissue is composed mostly of reticular fibers that form a netlike web that forms the internal framework of organs like the liver, lymph nodes, and bone marrow . (encyclopedia.com)
  • Connective tissue composed of ground substance and protein fibers differs from fibrous connective tissue in that it contains more ground substance. (encyclopedia.com)
  • Fibrocartilage contains densely packed, regularly arranged collagen fibers that impart great strength to this connective tissue. (encyclopedia.com)
  • Both the ground substance and proteins (fibers) create the matrix for connective tissue. (wikipedia.org)
  • Reticular connective tissue is a type of tissue found in the body that is supported with a branching framework of collagen fibers known as reticular fibers. (wisegeek.com)
  • These fibers are present in many types of connective tissue and are particularly heavily concentrated in this tissue. (wisegeek.com)
  • In reticular connective tissue, cells that secrete type III collagen work together to create a stable lattice of fibers. (wisegeek.com)
  • The tissue is similar to connective tissue with a high amount of elastic fibers, except that in reticular connective tissue, the collagen fibers are branched, while elastic fibers lie parallel to each other. (wisegeek.com)
  • Specialized cells are involved in the formation of new reticular fibers and the maintenance of existing fibers that are already part of the collagen lattice in the reticular connective tissue. (wisegeek.com)
  • Fibrous connective tissue , sometimes referred to as FCT, is tissue made up of high-strength, slightly stretchy fibers. (wisegeek.com)
  • As the cells and fibers in this tissue are so densely packed together, they are sometimes simply referred to as dense connective tissues. (wisegeek.com)
  • In hematopoietic and lymphatic tissues, reticular fibers made by reticular cells provide the stroma-or structural support-for the parenchyma-or functional part-of the organ. (wikipedia.org)
  • All connective tissue apart from blood and lymph consists of three main components: fibers ( elastic and collagenous fibers ), ground substance and cells . (wn.com)
  • The interaction of the fibers, the extracellular matrix and the water, together, form the pliable connective tissue as a whole. (lulu.com)
  • Connective tissue fibers form capsules and membranes which surround organs, and form ligaments and tendons which bind bones to each other or to muscles. (ubc.ca)
  • The reticular dermis is a dense irregular connective tissue with fibroblasts and densely packed collagen fibers, organized in intertwined fascicles. (shutterstock.com)
  • The primary elements of connective tissue include a ground substance, fibers, and cells. (thoughtco.com)
  • The ground substance acts as a fluid matrix that suspends the cells and fibers within the particular connective tissue type. (thoughtco.com)
  • Connective tissue fibers and matrix are synthesized by specialized cells called fibroblasts . (thoughtco.com)
  • This image of loose connective tissue shows collagenous fibers (red), elastic fibers (black), matrix, and fibroblasts (cells that produce the fibers). (thoughtco.com)
  • Loose connective tissue is named so because of the 'weave' and type of its constituent fibers. (thoughtco.com)
  • The three main types of loose connective fibers include collagenous, elastic, and reticular fibers. (thoughtco.com)
  • These fibers help to strengthen connective tissue. (thoughtco.com)
  • Reticular fibers join connective tissues to other tissues. (thoughtco.com)
  • Dense connective tissue is composed of large amounts of closely packed collagenous fibers. (thoughtco.com)
  • In comparison to loose connective tissue, dense tissue has a higher proportion of collagenous fibers to ground substance. (thoughtco.com)
  • Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. (bioontology.org)
  • Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues. (bioontology.org)
  • A nerve is made up of many nerve cell fibers (neurons) bound together by connective tissue. (majortests.com)
  • The endoneurium which consists of a thin layer of loose connective tissue surrounds the individual nerve fibers. (majortests.com)
  • The fibroblasts are cells of connective tissue that produces and secretes fibers (e.g. collagens , reticular and elastic fibers). (biology-online.org)
  • 14) During the early phase of immobilization, loss of muscle length is primarily due to shortening of muscle-associated connective tissue, which is later followed by actual shortening of muscle fibers. (chiro.org)
  • The fibers of loose connective tissue are loosely arranged between cells. (majortests.com)
  • Areolar connective tissue consists of fibers (collagen, elastic, and reticular) and several kinds of cells (fibroblasts, macrophages, plasma cells, adipocytes, and mast cells) embedded in a semifluid ground substance. (majortests.com)
  • Proteoglycans are substances found on type I collagen fibrils (minute fibers) in various tissues. (brightsurf.com)
  • Connective tissues are composed of fibers forming a network and a semi fluid intracellular matrix. (differencebetween.net)
  • In some tissues, fibers crisscross and form a mesh. (magenarquitectos.com)
  • The fibers are mainly composed of type I collagen.Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that generate the fibers.Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. (magenarquitectos.com)
  • In dense irregular connective tissue, the direction of fibers is random. (magenarquitectos.com)
  • The dense elastic tissue is the only type of dense connective tissue that is elastic and it is mainly composed of elastin fibers. (magenarquitectos.com)
  • Dense connective tissue, also called dense fibrous tissue, is a type of connective tissue with fibers as its main matrix element. (magenarquitectos.com)
  • Using two-photon imaging, we demonstrated that Hyp induced photosensitized modification of collagen fibers in native tissues. (spie.org)
  • We showed that Hyp-mediated processes in collagen tissues may be used for the selective modification of collagen fibers. (spie.org)
  • Three kinds of fibers generally form the supportive material in connective tissue proper. (thefreedictionary.com)
  • The type of connective tissue that forms tendons tendon, tough cord composed of closely packed white fibers of connective tissue that serves to attach muscles to internal structures such as bones or other muscles. (thefreedictionary.com)
  • It differs from the other three tissues in that the extracellular components (fibers and intercellular substances) are abundant. (thefreedictionary.com)
  • Some examples of structures in the body that include this type of connective tissue include the liver, spleen, and lymph nodes. (wisegeek.com)
  • Mesenchyme is a type of connective tissue found in developing organs of embryos that is capable of differentiation into all types of mature connective tissue. (wikipedia.org)
  • In vertebrates, the most common type of connective tissue is loose connective tissue . (thoughtco.com)
  • Another type of connective tissue is dense or fibrous connective tissue, which can be found in tendons and ligaments. (thoughtco.com)
  • In addition the adipose, one type of connective tissue is responsible for providing heat in the body. (differencebetween.net)
  • Dense regular connective tissue , which forms organized structures, is a major functional component of tendons , ligaments and aponeuroses , and is also found in highly specialized organs such as the cornea . (wikipedia.org)
  • Elastin is the major component of ligaments (tissues which attach bone to bone). (rxlist.com)
  • Connective tissue disease is a group of autoimmune conditions marked by inflammation of the muscle fascias, ligaments and skin . (rxlist.com)
  • Fibrous connective tissue also forms very strong, elastic structures called ligaments and tendons. (wisegeek.com)
  • Tendons and ligaments are examples of dense regular connective tissue. (thoughtco.com)
  • Connective tissue is not limited to ligaments and tendons. (ideafit.com)
  • [8] Loose and dense connective tissue are distinguished by the ratio of ground substance to fibrous tissue. (wikipedia.org)
  • Loose connective tissue has much more ground substance and a relative lack of fibrous tissue, while the reverse is true of dense connective tissue. (wikipedia.org)
  • [9] Other kinds of connective tissues include fibrous, elastic, and lymphoid connective tissues. (wikipedia.org)
  • [10] Fibroareolar tissue is a mix of fibrous and areolar tissue . (wikipedia.org)
  • Examples of non-fibrous CT include adipose tissue and blood. (wikipedia.org)
  • Two main types of fibrous connective tissue are found in the body: dense and loose. (encyclopedia.com)
  • Two other fibrous connective tissues are adipose and reticular tissue. (encyclopedia.com)
  • [10] Fibromuscular tissue is made up of fibrous tissue and muscular tissue . (wikipedia.org)
  • What is Fibrous Connective Tissue? (wisegeek.com)
  • The non-living portion of these tissues, such as that found in fibrous connective tissue, is known collectively as matrix. (wisegeek.com)
  • There are many kinds of connective tissue in the body, and many of these tissues contain the fibrous strands of the protein collagen, which adds strength. (wisegeek.com)
  • Fibrous connective tissue, however, does not contain any living cells, as its main function is support and structure throughout the body. (wisegeek.com)
  • Does repetitive motion affect fibrous connective tissue? (wisegeek.com)
  • I have a lot of pain and inflammation in my wrist, but don't know if that is from damaged fibrous tissue or something else. (wisegeek.com)
  • Connective tissue' is a fibrous and most diverse tissue. (lulu.com)
  • Fatty tissue is fibrous connective tissue unfiltrated with fat. (usf.edu)
  • Fibrous collagen is widespread in biological tissues, while elastin has only been found in animals with a backbone. (medindia.net)
  • Dense Fibrous Connective Tissue. (thoughtco.com)
  • Unlike epithelial tissue , which has cells that are closely packed together, connective tissue typically has cells scattered throughout an extracellular matrix of fibrous proteins and glycoproteins attached to a basement membrane. (thoughtco.com)
  • This image of the dermis of the skin shows dense fibrous connective tissue. (thoughtco.com)
  • Some connective tissues are not fibrous. (biology-online.org)
  • Dense irregular connective tissue also makes up submucosa of the digestive tract, fibrous capsules of joints and lymph nodes, and some types of fascia. (magenarquitectos.com)
  • and fascia fascia , fibrous tissue network located between the skin and the underlying structure of muscle and bone. (thefreedictionary.com)
  • Like other connective tissues, bone consists of cells, fibres , and ground substance, but, in addition, the extracellular components are impregnated with minute crystals of calcium phosphate in the form of the mineral hydroxyapatite . (britannica.com)
  • Systems and methods for replacing, reconstructing and/or securing synthetic or biological connective tissue to interior and/or exterior bone surfaces. (google.com)
  • 3 . A method for securing a connective tissue to a bone surface as recited in claim 2 , wherein the step for inserting the soft tissue graft further comprises a step for extending a portion of the soft tissue graft outside the bone tunnel. (google.com)
  • 5 . A method for securing a connective tissue to a bone surface as recited in claim 2 , further comprising a step for coupling the connective tissue to the anchoring device. (google.com)
  • 7 . A method for securing a connective tissue to a bone surface as recited in claim 2 , further comprising a step for placing the anchoring device within the tunnel such that the anchoring device lays substantially flush with the outside cortex of the bone tunnel. (google.com)
  • 8 . A method for securing a connective tissue to a bone surface as recited in claim 7 , wherein the step for placing the anchoring device includes a step for embedding one or more spikes in the outside cortex of the bone tunnel. (google.com)
  • 9 . A method for securing a connective tissue to a bone surface as recited in claim 2 , wherein the anchoring device pivotally connects to the head of the retention device. (google.com)
  • The center is also a hub for education and training of pre- and post-doctoral fellows in the arthritides and related diseases and has outreach programs to better educate private physicians in Tennessee and the public about arthritis, bone, joint and connective tissue diseases. (uthsc.edu)
  • Research has revealed that while a bacterial infection is responsible for the initiation of the inflammation of periodontitis, the destruction of the bone and connective tissue itself is mediated by enzymes, produced by the body in response to the bacterial infection," said Dr. (thefreedictionary.com)
  • These types of tissues do not stretch the muscles (as in the yang form of yoga) but they stretch and exercise the bone and joints areas of the body. (casapalmera.com)
  • ICD-9 code 171.6 for Malignant neoplasm of connective and other soft tissue of pelvis is a medical classification as listed by WHO under the range -MALIGNANT NEOPLASM OF BONE, CONNECTIVE TISSUE, SKIN, AND BREAST (170-176). (aapc.com)
  • The intercellular substance of bone bone, hard tissue that forms the skeleton of the body in vertebrate animals. (thefreedictionary.com)
  • Reticular connective tissue forms the bone marrow and the framework for lymphoid tissue. (thefreedictionary.com)
  • Connective tissue diseases are disorders featuring abnormalities involving the collagen and elastin. (medicinenet.com)
  • The connective tissues are composed of two major structural molecules, collagen and elastin . (rxlist.com)
  • In patients with connective tissue diseases, it is common for collagen and elastin to become injured by inflammation. (rxlist.com)
  • Based on the two major constituents of the connective tissue, collagen and elastin, these disorders can be divided into "collagenopathies" and "elastinopathies" [ 5 , 6 ]. (hindawi.com)
  • Heritable disorders of connective tissue are a heterogenous group of genetic conditions caused by defects of extracellular matrix elements such as collagen, elastin, mucopolysaccharides or related biomolecules. (clinicaltrials.gov)
  • A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides. (leo.org)
  • Only recently discovered in animal tissues, researchers have traced this property to elastin and found that when exposed to sugar, the elastin protein sometimes slows or stops its ferroelectric switching. (medindia.net)
  • The research team separated the aortic tissue into two types of proteins, collagen and elastin. (medindia.net)
  • The research team has focused solely on the aortic tissues, but this finding likely applies to other biological tissues that have the protein elastin, such as the lungs and skin. (medindia.net)
  • These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. (primidi.com)
  • Connective tissues contain mainly collagen, elastin and proteoglycan. (hubpages.com)
  • Loose connective tissue (also known as areolar connective tissue) is widely distributed throughout the body and provides the loose packing material between glands, muscles, and nerves. (encyclopedia.com)
  • The delicate and fragile areolar connective tissue forms a soft packing around organs. (ubc.ca)
  • The types of loose connective tissue are areolar connective tissue, adipose tissue, and reticular connective tissue. (majortests.com)
  • Areolar connective tissue is located in the subcutaneous layer deep to skin and around blood vessels, nerves, and body organs. (majortests.com)
  • 2) Structure of Connective tissues 3) The function of Connective tissues - Binding - Supporting - Packaging 4) Types of Connective tissues - Dense connective tissue (Bones, Tendon) - Areolar / Loose / Filler Connective tissues - Skeletal Connective Tissue (Ligament. (schooltube.com)
  • Dense Irregular Connective Tissue Stratified Squamous Epithelium Simple Squamous Epithelium Areolar And Adipose Tissue Dense Regular Connective Tissue Reset (magenarquitectos.com)
  • Areolar connective tissue 40X Areolar connective tissue has no obvious structure, like layers or rows of cells. (magenarquitectos.com)
  • Adipose tissue gives "mechanical cushioning" to the body, among other functions. (wikipedia.org)
  • Fat cells or adipose tissue, is a connective tissue which not only cushions body organs but also insulates them and provides reserve energy fuel. (ubc.ca)
  • Adipose tissue forms an insulating layer under the skin, storing energy in the form of fat. (thoughtco.com)
  • Adipose tissue is a form of loose connective tissue that stores fat . (thoughtco.com)
  • Adipose tissue also produces endocrine hormones that influence activities such as blood clotting, insulin sensitivity, and fat storage. (thoughtco.com)
  • Most adipose tissue is described as white adipose which functions in the storage of energy. (thoughtco.com)
  • Adipose tissue is a loose connective tissue in which the cells, called adipocytes, are specialized for storage of triglycerides (fats). (majortests.com)
  • It is sometimes said to be the same as undifferentiated connective tissue disease , [1] but other experts specifically reject this idea [7] because undifferentiated connective tissue disease is not necessarily associated with serum antibodies directed against the U1-RNP , and MCTD is associated with a more clearly defined set of signs/symptoms. (wikipedia.org)
  • When these conditions have not developed the classic features of a particular disease, doctors will often refer to the condition as 'undifferentiated connective tissue disease. (rxlist.com)
  • Individuals with undifferentiated connective tissue disease may never develop a fully definable condition or they may eventually develop a classic connective tissue disease. (rxlist.com)
  • Sometimes, in the early stages, doctors simply refer to the 'undifferentiated' condition as a collagen vascular disease or undifferentiated connective tissue disease (UCTD) until more defined symptoms appear. (rxlist.com)
  • The area beneath the stratified squamous epithelium shown in slide 33 is the dermis, which is composed of dense irregular connective tissue. (magenarquitectos.com)
  • Mixed connective tissue disease commonly abbreviated as MCTD , is an autoimmune disease characterized by the presence of elevated blood levels of a specific autoantibody, now called anti-U1 ribonucleoprotein (RNP) together with a mix of symptoms of systemic lupus erythematosus (SLE), scleroderma , and polymyositis . (wikipedia.org)
  • Mixed connective tissue disease is considered an 'overlap' of three connective tissue diseases, systemic lupus erythematosus , scleroderma , and polymyositis . (rxlist.com)
  • Diagnosis of mixed connective tissue disease is supported by detecting abnormal antibodies in the blood . (rxlist.com)
  • Treatment of mixed connective tissue disease is directed at suppressing immune -related inflammation of tissues. (rxlist.com)
  • This implies that the characteristic features that are used to define the classic connective tissue disease are not present, but some symptoms or signs of connective disease exist. (rxlist.com)
  • Mixed connective tissue disease, as first described in 1972, is 'classically' considered an 'overlap' of three diseases, systemic lupus erythematosus, scleroderma, and polymyositis. (rxlist.com)
  • What are causes and risk factors for mixed connective tissue disease? (rxlist.com)
  • The most significant causes and risk factors for developing mixed connective tissue disease are certain gene patterns that are inherited from ancestors. (rxlist.com)
  • There is no known environmental toxin that has been shown to cause mixed connective tissue disease. (rxlist.com)
  • What are signs and symptoms of mixed connective tissue disease? (rxlist.com)
  • The signs and symptoms of mixed connective tissue disease vary greatly from one individual affected to another. (rxlist.com)
  • A connective tissue disease is any disease that has the connective tissues of the body as a primary target of pathology . (rxlist.com)
  • Collagen vascular disease is a somewhat antiquated term used to describe diseases of the connective tissues that typically include diseases that can be (but are not necessarily) associated with blood vessel abnormalities. (rxlist.com)
  • It is likely that a combination of genetic risks and environmental factors are necessary for the development of connective tissue disease. (rxlist.com)
  • A common symptom of connective tissue (CT) disease is nonspecific fatigue . (rxlist.com)
  • Depending on which connective tissue disease is present, and how active it is, a wide variety of symptoms may occur. (rxlist.com)
  • The doctor can sometimes detect a particular connective tissue disease simply by the physical examination. (rxlist.com)
  • Frequently, blood testing, X-ray examination, and other tests can help in making a diagnosis of connective tissue disease. (rxlist.com)
  • What are genetic risk factors for developing connective tissue disease? (rxlist.com)
  • What autoimmune diseases are associated with connective tissue disease? (rxlist.com)
  • He said that these networks of reticular and other connective tissues hold many secrets about how the body works and how disease begins. (wisegeek.com)
  • Arthritis is one common disease which can affect connective tissue. (wisegeek.com)
  • Overcoming the foreign-body response to in-body monitoring for long-term use, its tissue -integrated biosensors open the door to accessing, connecting and applying body chemistry in unprecedented ways, transforming the management of personal health and disease. (wn.com)
  • Pulmonary Manifestations and Progression of Lung Disease in Juvenile-onset Mixed Connective Tissue Disease. (nih.gov)
  • Read more about Connective Tissue Disease . (primidi.com)
  • Lupus is a type of chronic inflammatory disease which occurs when the body's immune system turns against its own tissues and organs. (ihealthdirectory.com)
  • CT Features of the Usual Interstitial Pneumonia (UIP) Pattern: Differentiating Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD) From Idiopathic Pulmonary Fibrosis (IPF). (sclero.org)
  • Researchers supported by these grants will study the functions of connective tissue proteins and how mutations result in disease. (brightsurf.com)
  • Cutis laxa is a connective tissue disease characterized by sagging skin, premature wrinkling and reduced skin elasticity. (brightsurf.com)
  • Connective tissue diseases (CTDs) are a group of closely related multisystem disease conditions with many overlapping clinical features. (thermofisher.com)
  • It is a chronic, inflammatory disease that often progresses to a more complex, systemic disorder that can affect other tissues and organs in the body such as joints, skin, kidneys, lungs, nervous system, and the intestinal tract. (thermofisher.com)
  • A case of mixed connective tissue disease combined with sarcoidosis. (bmj.com)
  • The cells of connective tissue include fibroblasts , adipocytes , macrophages , mast cells and leucocytes . (wikipedia.org)
  • Fibroblasts are the cells responsible for the production of connective tissue. (lulu.com)
  • The connective tissue cells may be in the form of fibroblasts , adipocytes , and [blood cell]]s (such as macrophages , mast cells , etc. (biology-online.org)
  • Here is an article by Helene M. Langevin where she discusses her research into long held (~30 minute) stresses on connective tissues and how it can cause a remodelling of the tissue and the architecture of the fibroblasts. (yinyoga.com)
  • We also saw that the fibroblasts initiated a specific Rho-dependent cytoskeletal reorganization that was required for the tissue to fully relax. (yinyoga.com)
  • CTGF is expressed by several stromal cell types, including endothelial cells, fibroblasts, smooth muscle cells, and myofibroblasts, and some epithelial cell types in diverse tissues. (aacrjournals.org)
  • Consistent with its role in connective tissue biology, CTGF enhances stromal extracellular matrix synthesis ( 16 ) and stimulates proliferation, cell adhesion, cell spreading, and chemotaxis of fibroblasts ( 10 , 16 , 21 ). (aacrjournals.org)
  • This book deals primarily with the principal extracellular macromole- cules of animal connective tissues. (springer.com)
  • The properties of the cells and the composition and arrangement of the extracellular matrix elements vary tremendously, giving rise to an amazing diversity of connective tissues, each uniquely adapted to perform its specific function in the body. (ubc.ca)
  • Connective tissues are characterized by abundant amounts of extracellular matrix in which a variety of cell types are dispersed. (ubc.ca)
  • Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. (primidi.com)
  • MSM (Methylsulfonyl methane) - helps support the structure of connective tissues in your joints. (xtend-life.com)
  • Other tissues (epithelia, muscles, nerves) are supported, surrounded and held in place by connective tissues. (ubc.ca)
  • 8) "Abnormal movement patterns can have important influences on the connective tissues that surround and infiltrate muscles. (chiro.org)
  • The muscles are attached to the connective tissues, so, they all get stronger. (ideafit.com)
  • In addition to these structures, which are derived from the neural crest, the crest-derived connective tissues and mesodermal muscles also form different patterns in each of the branchial arches. (nih.gov)
  • In addition, anomalous first arch-type muscles were found associated with the ectopic skeletal tissues in the second arch. (nih.gov)
  • Diseases of connective tissue that are strictly inheritable (due to genetic inheritance ) include Marfan syndrome (can have tissue abnormalities in the heart , aorta , lungs , eyes, and skeleton ) and Ehlers-Danlos syndrome (may have loose, fragile skin or loose [ hyperextensible ] joints). (rxlist.com)
  • Other diseases of connective tissue do not have specific gene abnormalities as their sole cause. (rxlist.com)
  • Other diseases of connective tissue cannot be regularly defined by selected gene abnormalities, such as systemic lupus erythematosus or scleroderma . (rxlist.com)
  • Eight new research grants funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) will shed light on heritable diseases of connective tissue. (brightsurf.com)
  • The tissue can also be found between joints such as the knees to prevent the connecting bones from grinding together during movement. (wisegeek.com)
  • Delicate ingredients - Many of these nutrients can easily be destroyed by stomach acids long before they reach your joints and connective tissues. (xtend-life.com)
  • Despite the fact that our Total Balance, Green Lipped Mussel Powder and Omega 3/DHA products are excellent for supporting healthy inflammation management and the healthy function of your connective tissue and joints, many customers still need a 'booster' formulated to help people suffering from joint and connective tissue discomfort, Not Just Joints is just the boost you need. (xtend-life.com)
  • Another paper examines the importance of elastic tissues in the reactions of connective tissue including diseases of the vascular and pulmonary systems. (elsevier.com)
  • As simple as elastic tissues appear to be, these can be models in studies of the basic structure and function of other more complicated tissues. (elsevier.com)
  • The structure of the collagen lattice provides more strength and support to the underlying tissue and is less springy than elastic tissue. (wisegeek.com)
  • Dense connective tissue can be categorized into dense regular , dense irregular , and elastic connective tissues. (thoughtco.com)
  • This may be because connective tissue is usually fairly elastic and a tumor pushes out the normal tissue before it is noticed. (knowcancer.com)
  • Examples include the dense elastic connective tissue in the vocal cords. (magenarquitectos.com)
  • Therefore, the dense elastic tissue is yellow in color while other dense connective tissues are white in color. (magenarquitectos.com)
  • 9 . The connective tissue apparatus of claim 1 , wherein the connective tissue is a tendon. (google.com.au)
  • Tbx4 and tbx5 acting in connective tissue are required for limb muscle and tendon patterning. (nih.gov)
  • This set of 4 slides is designed to aid your study of connective tissue histology. (carolina.com)
  • The terms "collagen diseases" was coined originally to denote a group of disorders which showed common features such as multisystem involvement, fibrinoid degeneration of connective tissue demonstrable on histology and caused by immunological processes. (hubpages.com)
  • Histology Learning System [ Connective Tissue, dense/loose irregular connective tissue] These muscle bundles are responsible for erection of the nipples. (magenarquitectos.com)
  • This knowledge has the potential to lead to new treatments for not only patients with HDCT, but also for pathological conditions associated with the weakness of connective tissues in aging. (clinicaltrials.gov)
  • To understand the origin of tissue fluid and intercellular ground substance. (magenarquitectos.com)
  • It cannot be sharply delimited from the blood, whose cells may give rise to connective tissue cells, and whose plasma components continually interchange with and augment the ground substance of connective tissue. (thefreedictionary.com)
  • This image shows a sample of fat tissue with fat cells (adipocytes, blue) surrounded by fine strands of supportive connective tissue. (thoughtco.com)
  • 2. Supportive Connective Tissuea. (slideserve.com)
  • Other authors discuss the diseases of collagen and related tissues (rheumatic fever, rheumatoid arthritis, systemic lupus erythematous, osteoarthritis, osteoporosis), as well as the aging process. (elsevier.com)
  • Because of the wide distribution of connective tissues within the human body, diseases that affect connective tissue cells or ECM proteins often have systemic effects. (hindawi.com)
  • A total of 187 specimens from 142 subjects with rheumatoid arthritis, systemic lupus erythematosus, other connective tissue diseases, and controls were placed in cell culture. (rupress.org)
  • Connective tissue ( CT ) is one of the four basic types of animal tissue , along with epithelial tissue , muscle tissue , and nervous tissue . (wikipedia.org)
  • Ciliated epithelial tissue, which is covered with long waving hair-like projections (cilia). (usf.edu)
  • It holds organs in place and attaches epithelial tissue to other underlying tissues. (thoughtco.com)
  • Specialized epithelial tissue containing sensory nerve endings is found in the skin, eyes, ears, nose and on the tongue. (majortests.com)
  • 3. Secretion in glands: epithelial tissue is specialized to secrete specific chemical substances such as enzymes, hormones. (majortests.com)
  • Tissues Epithelial tissues Epithelial tissue covers the whole surface of the body. (majortests.com)
  • Connective Tissue Gene Tests (CTGT) has added 12 new assays to its menu of molecular diagnostics for inherited disorders affecting connective tissues. (genomeweb.com)
  • Any of a group of noninheritable diseases that affect the connective tissue, such as rheumatic fever and rheumatoid arthritis, and that are characterized by fever, pain, stiffness, and inflammation. (dictionary.com)
  • Rheumatoid arthritis is a connective tissue disorder which manifests in various clinical presentations. (hubpages.com)
  • PUBLIC HEALTH RELEVANCE: This project attempts to provide researchers and clinicians with a biomarker - the Connective Tissue Motion Measure - capable of documenting and monitoring the functional status of human connective tissues. (sbir.gov)
  • Researchers at the University of Washington and Boston University have discovered that a certain type of protein found in organs that repeatedly stretch and retract - such as the heart and lungs - is the source for a favorable electrical property that could help build and support healthy connective tissues. (medindia.net)
  • Connective tissue ( CT ) is one of the four types of biological tissue that support, connect, or separate different types of tissues and organs in the body. (wn.com)
  • Nervous tissue is specialized to react to stimuli and to conduct impulses to various organs in the body which bring about a response to the stimulus. (majortests.com)
  • The connective tissues are vital and significant component of almost all organs in the body. (differencebetween.net)
  • You just viewed M1 Cells and Tissues- Connective... . (merlot.org)
  • Connective tissues are the framework of the cells of the body. (rxlist.com)
  • The connective tissues are the structural portions of our body that essentially hold the cells of the body together. (rxlist.com)
  • It's fascinating how the cells of the human body are able to detect when body tissue is too old to function properly. (wisegeek.com)
  • Then the tissue cells break down and new ones are generated. (wisegeek.com)
  • Some of these tissues, such as blood, contain living cells that are grouped together and carry nutrients throughout the body. (wisegeek.com)
  • Its uniqueness, compared to other tissues, lies in its composition of a diverse set of constituents-cells, fibres, blood vessels-scattered around in an ECM. (hindawi.com)
  • Cells of the immune system, such as macrophages, mast cells, plasma cells and eosinophils are found scattered in loose connective tissue, providing the ground for starting inflammatory and immune responses upon the detection of antigens. (wikipedia.org)
  • the cells of the connective tissue per see which secrete the matrix or maintain it. (ubc.ca)
  • In most connective tissues, once the matrix is produced, the undifferentiated cells lose their capacity for cell division and become mature cells whose name ends in -cyste . (ubc.ca)
  • the accessory cells which are supported by the connective tissue. (ubc.ca)
  • antibody-producing plasma cells that are mobile and migrate into the connective tissue matrix from the blood stream. (ubc.ca)
  • They are involved in the body defense and in the elimination of dying or dead tissue cells. (ubc.ca)
  • Cells adhesion proteins allow the connective tissue cells to attach themselves to matrix elements. (ubc.ca)
  • Also classified as connective tissue are the various cells in the tissue interstices (e.g. macrophages) and in the blood. (thefreedictionary.com)
  • Specialized connective tissues include a number of different tissues with specialized cells and unique ground substances. (thoughtco.com)
  • a contractile tissue of the body and is derived from the MESODERMAL layer of embryonic germ cells. (majortests.com)
  • Nerve tissue ( as in the brain, spinal cord and peripheral nerves that branch throughout the body) are all made up of specialized nerve cells called neurons. (majortests.com)
  • 1. Protection: epithelial cells from the SKIN protect underlying tissue from mechanical injury, harmful chemicals, invading bacteria and from excessive water. (majortests.com)
  • Tissues are groups of similar cells working together to perform a specific function and are the living fabric that holds together the human design. (majortests.com)
  • The adipocytes are connective tissue cells that are specialised in storing fat (lipid). (biology-online.org)
  • The molecule's involvement in fibroblast shape change suggested that the cells are able to reduce the tissue tension by adjusting how strongly and where they are gripping the surrounding connective tissue or muscle. (yinyoga.com)
  • True Connective Tissue Cells. (slideserve.com)
  • 5. Name and describe the types of cells found in connective tissue. (majortests.com)
  • Disorders of connective tissue -- the material between cells that gives tissues form and strength -- include such conditions as osteogenesis imperfecta and Ehlers-Danlos syndrome, and, in total, may affect as many as a million people in the United States. (brightsurf.com)
  • The tissues around the infected area receive an increased blood supply, and the cell walls produce gaps allowing the large immune system blood cells, or macrophages, to pass through. (vitanetonline.com)
  • Cells make up all tissues, tissues make up organs, organs make up systems and systems make up organisms. (differencebetween.net)
  • Cells have different types that make up different tissues. (differencebetween.net)
  • Common sense tells us that epithelial cells make up epithelial tissues. (differencebetween.net)
  • The cells in the connective tissue are scattered in the matrix. (differencebetween.net)
  • Tissues that establish association between cells and organs of the body is termed as connective tissue. (assignmenthelp.net)
  • Connective tissues are of different types depending upon the cells, their structure and their distance. (assignmenthelp.net)
  • Differential cDNA microarray analyses showed that connective tissue growth factor (CTGF) was expressed at low levels in nontumor-promoting prostate stromal cells and was constitutively expressed in tumor-promoting prostate stromal cells. (aacrjournals.org)
  • supportive tissue widely distributed in the body, characterized by large amounts of intercellular substance and relatively few cells. (thefreedictionary.com)
  • The intercellular material, or matrix, is produced by the cells and gives the tissue its particular character. (thefreedictionary.com)
  • There are many different collagen proteins that vary in amount in each tissue of the body. (rxlist.com)
  • Hyaluronic Acid: Complex combination of polysaccharides and proteins found in "true" or proper connective tissue. (slideserve.com)
  • The six major functions of proteins are to repair and maitenance- protein is vital in the maintenance of body tissue, including development and repair. (majortests.com)
  • Liquid connective tissue also called fluid connective tissue are present in the form of liquid and hence helps in the circulation of important metabolites. (assignmenthelp.net)
  • 12) "A consistent absence of stress leads to connective tissue atrophy, architectural disorganization, fibrosis, adhesions and contractures. (chiro.org)
  • The researcher will study whether disruption of this interaction leads to connective tissue disorders. (brightsurf.com)
  • See detailed information below for a list of 8 causes of Connective tissue weakness , Symptom Checker , including diseases and drug side effect causes. (rightdiagnosis.com)
  • The following medical conditions are some of the possible causes of Connective tissue weakness. (rightdiagnosis.com)
  • How Common are these Causes of Connective tissue weakness? (rightdiagnosis.com)
  • Research more detailed information about the causes of Connective tissue disorders , other possibly hidden causes of Connective tissue disorders , or other general information about Connective tissue disorders . (cureresearch.com)
  • In doing so, however, I have treated cursorily many important aspects of connective tissue biology that appeared to be only indirectly relevant to the principal questions asked. (springer.com)
  • International Review of Connective Tissue Research covers a broad range of aspects of connective tissue metabolism and structure, and other relevant material in the field of connective tissue research. (elsevier.com)
  • Examples of connective tissue disorders include Marfan syndrome, Ehlers-Danlos syndrome, Stickler syndrome, and many others. (albertahealthservices.ca)
  • Several cellular and molecular components of connective tissue function in defense against invading bacteria or chemical substances. (ubc.ca)
  • Heritable disorders of connective tissue are genetic conditions that can affect the skin and other parts of the body. (clinicaltrials.gov)
  • To perform one-time and long-term studies of people who have heritable disorders of connective tissue. (clinicaltrials.gov)
  • Heritable disorders of connective tissue are rare diseases that result from mutations in genes responsible for building tissues. (brightsurf.com)
  • The Request for Applications (RFA) was issued in response to recommendations made at the Third Workshop on Heritable Disorders of Connective Tissue that was held at NIH in November 2001 and sponsored by NIAMS, the NIH Office of Rare Diseases, and several nonprofit organizations outside NIH. (brightsurf.com)
  • [6] [7] Connective tissue proper consists of loose connective tissue and dense connective tissue (which is further subdivided into dense regular and dense irregular connective tissues . (wikipedia.org)
  • There are three main groups of connective tissues: loose connective tissue, dense connective tissue, and specialized connective tissue. (thoughtco.com)
  • Loose connective tissues provide support, flexibility, and strength required to support internal organs and structures such as blood vessels , lymph vessels , and nerves. (thoughtco.com)
  • It is thicker and stronger than loose connective tissue and forms a protective capsule layer around organs such as the liver and kidneys . (thoughtco.com)
  • EXERCISE 6 - Loose connective tissue Step 1: Which of the labeled structures is responsible for that quality? (magenarquitectos.com)
  • In the central nervous system , the three outer membranes (the meninges ) that envelop the brain and spinal cord are composed of connective tissue. (wikipedia.org)
  • Submicroscopic Cytochemistry, Volume II: Membranes, Mitochondria, and Connective Tissues presents laboratory findings and theoretical aspects of the cytochemistry of cellular membranes, mitochondria, and connective tissues. (scribd.com)
  • Emphasis is on the molecular and macromolecular organization of cellular membranes, along with the origin and distribution of the major macromolecular aggregates of connective tissue. (scribd.com)
  • The epithelial tissues are found above the basement membranes. (differencebetween.net)
  • What diseases characteristically affect connective tissue? (rxlist.com)
  • What do you guys know about ways to strengthen connective tissue? (elitefitness.com)
  • Treatment is often directed at suppressing the inflammation present in the tissues by using anti-inflammatory and immunosuppressive medications. (medicinenet.com)
  • Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues ( autoimmunity ). (rxlist.com)
  • Damage to this tissue or degenerative diseases may cause a loss of support, grinding bones, inflammation , and pain. (wisegeek.com)
  • Inflammation is a defensive response of connective tissue at the site of infection or injury. (ubc.ca)
  • We hypothesize that pain-related fear leads to a cycle of decreased movement, connective tissue remodeling, inflammation, nervous system sensitization and further decreased mobility. (chiro.org)
  • Not all authorities include blood [2] or lymph as connective tissue because they lack the fiber component. (wikipedia.org)
  • Blood and lymph are fluid connective tissues. (wikipedia.org)
  • Not all authorities include blood or lymph as connective tissue. (wn.com)
  • Much of the dermis layer of the skin is composed of dense irregular connective tissue. (thoughtco.com)
  • Dense Irregular Connective Tissue This image of the dermis shows irregularly oriented dense connective tissue. (magenarquitectos.com)
  • The goal of the society is to advance the care of patients with connective tissue tumors and to increase knowledge of all aspects of the biology of these tumors, including basic and clinical research. (ctos.org)
  • Feb 18, 2015 - dense irregular connective tissue labeled - Google Search Each adipose cell, or adipocyte, has its cytoplasm stretched around a central globule of fat (fig. Examine the following virtual slides and identify, draw & label features and note their function. (magenarquitectos.com)
  • They are dense regular connective tissue and dense irregular connective tissue. (magenarquitectos.com)
  • Key Difference - Dense Regular vs Dense Irregular Connective Tissue. (magenarquitectos.com)
  • We identify muscle connective tissue as the site of action of these transcription factors and show that N-Cadherin and beta-Catenin are key downstream effectors acting in muscle connective tissue and regulating soft-tissue morphogenesis. (nih.gov)
  • Our results suggest that a focus on connective tissue is required to understand the etiology of diseases affecting soft tissue formation. (nih.gov)
  • Cancer of the connective, or soft tissue is known as soft-tissue sarcoma . (knowcancer.com)
  • In its early stages, soft-tissue sarcoma normally does not display any symptoms. (knowcancer.com)
  • Soft tissue engineering with micronized-gingival connective tissues. (nextbio.com)
  • Also called cerebrospinal fluid is also a liquid connective tissue found in brain and spine. (assignmenthelp.net)
  • If you are worried about the assignment and projects on liquid connective tissue, get in touch with the tutor of www.assignmenthelp.net. (assignmenthelp.net)
  • These are considered classic connective tissue diseases. (rxlist.com)