Connective tissue. Medical search

Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.

A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.

A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.

A group of cells that includes FIBROBLASTS, cartilage cells, ADIPOCYTES, smooth muscle cells, and bone cells.

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.

Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.

A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).

A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue.

Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)

Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.

An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.

An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.

A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.

The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

A CCN protein family member found at high levels in NEPHROBLASTOMA cells. It is found both intracellularly and in the EXTRACELLULAR MATRIX and may play a role in the regulation of CELL PROLIFERATION and EXTRACELLULAR MATRIX synthesis.

A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.

Exposure of the root surface when the edge of the gum (GINGIVA) moves apically away from the crown of the tooth. This is common with advancing age, vigorous tooth brushing, diseases, or tissue loss of the gingiva, the PERIODONTAL LIGAMENT and the supporting bone (ALVEOLAR PROCESS).

Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.

Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state.

Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.

Surgical reshaping of the gingivae and papillae for correction of deformities (particularly enlargements) and to provide the gingivae with a normal and functional form, the incision creating an external bevel. (Dorland, 28th ed)

Oral tissue surrounding and attached to TEETH.

A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.

Bony cavity that holds the eyeball and its associated tissues and appendages.

Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).

Signal molecules that are involved in the control of cell growth and differentiation.

An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.

Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.

Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Classical loci in ACUPUNCTURE. They are main and collateral channels, regarded as a network of passages, through which vital energy (Qi) circulates and along which acupoints (ACUPUNCTURE POINTS) are distributed. The meridians are a series of 14 lines upon which more than 400 acupoints are located on the body. (The Pinyin Chinese-English Dictionary, p. 359; Dr. Wu Lancheng, Academy of Traditional Chinese Medicine, Beijing)

A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.

A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.

A fibrillar collagen consisting of three identical alpha1(III) chains that is widely distributed in many tissues containing COLLAGEN TYPE I. It is particularly abundant in BLOOD VESSELS and may play a role in tissues with elastic characteristics.

A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It may play an important role in the development of branched CAPILLARIES during EMBRYOGENESIS.

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

A wedge-shaped collar of epithelial cells which form the attachment of the gingiva to the tooth surface at the base of the gingival crevice.

A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

A family of structurally related collagens that form the characteristic collagen fibril bundles seen in CONNECTIVE TISSUE.

Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.

A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris.

A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.

A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.

Restoration of integrity to traumatized tissue.

A genus of large SEA CUCUMBERS in the family Holothuriidae possessing thick body walls, a warty body surface, and microscopic ossicles.

Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.

Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.

A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.

Glycoproteins which have a very high polysaccharide content.

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Components of the extracellular matrix consisting primarily of fibrillin. They are essential for the integrity of elastic fibers.

A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.

A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.

Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.

One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.

Layers of connective tissue of variable thickness. The superficial fascia is found immediately below the skin; the deep fascia invests MUSCLES, nerves, and other organs.

Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.

A collective term for diseases of the skin and its appendages and of connective tissue.

Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.

A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.

A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.

A genus of very large, epibenthic SEA CUCUMBERS in the family Stichopodidae, commercially harvested in Southeast Asia for food.

Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)

A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.

The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)

Elements of limited time intervals, contributing to particular results or situations.

Monomeric subunits of primarily globular ACTIN and found in the cytoplasmic matrix of almost all cells. They are often associated with microtubules and may play a role in cytoskeletal function and/or mediate movement of the cell or the organelles within the cell.

The properties, processes, and behavior of biological systems under the action of mechanical forces.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Any of certain small mammals of the order Hyracoidea.

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

The protein components that constitute the common core of small nuclear ribonucleoprotein particles. These proteins are commonly referred as Sm nuclear antigens due to their antigenic nature.

A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.

A biosynthetic precursor of collagen containing additional amino acid sequences at the amino-terminal and carboxyl-terminal ends of the polypeptide chains.

The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.

The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).

Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.

Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.

A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.

A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN TYPE I and COLLAGEN TYPE III. It is a heterotrimeric molecule composed of alpha1(V), alpha2(V) and alpha3(V) subunits. Several forms of collagen type V exist depending upon the composition of the subunits that form the trimer.

Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.

Enzymes that catalyze the degradation of collagen by acting on the peptide bonds.

A class of Echinodermata characterized by long, slender bodies.

A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.

An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.

The anteriorly located rigid section of the PALATE.

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and often re-expressed in tumors. It is present in the central and peripheral nervous systems as well as in smooth muscle and tendons. (From Kreis & Vale, Guidebook to the Extracellular Matrix and Adhesion Proteins, 1993, p93)

Inflammation of a muscle or muscle tissue.

A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)

Fleshy and reddish outgrowth of skin tissue found on top of the head, attached to the sides of the head, and hanging from the mandible of birds such as turkeys and chickens.

Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.

A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.

Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.

The region corresponding to the human WRIST in non-human ANIMALS.

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.

A scleroprotein fibril consisting mostly of type III collagen. Reticulin fibrils are extremely thin, with a diameter of between 0.5 and 2 um. They are involved in maintaining the structural integrity in a variety of organs.

Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.

Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.

A small leucine-rich proteoglycan found in a variety of tissues including CAPILLARY ENDOTHELIUM; SKELETAL MUSCLE; CARTILAGE; BONE; and TENDONS. The protein contains two glycosaminoglycan chains and is similar in structure to DECORIN.

Generalized or localized diffuse fibrous overgrowth of the gingival tissue, usually transmitted as an autosomal dominant trait, but some cases are idiopathic and others produced by drugs. The enlarged gingiva is pink, firm, and has a leather-like consistency with a minutely pebbled surface and in severe cases the teeth are almost completely covered and the enlargement projects into the oral vestibule. (Dorland, 28th ed)

Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)

Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.

ENDOPEPTIDASES which use a metal such as ZINC in the catalytic mechanism.

A phylum of the most familiar marine invertebrates. Its class Stelleroidea contains two subclasses, the Asteroidea (the STARFISH or sea stars) and the Ophiuroidea (the brittle stars, also called basket stars and serpent stars). There are 1500 described species of STARFISH found throughout the world. The second class, Echinoidea, contains about 950 species of SEA URCHINS, heart urchins, and sand dollars. A third class, Holothuroidea, comprises about 900 echinoderms known as SEA CUCUMBERS. Echinoderms are used extensively in biological research. (From Barnes, Invertebrate Zoology, 5th ed, pp773-826)

A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.

The minute vessels that connect the arterioles and venules.

Contractile tissue that produces movement in animals.

The process of bone formation. Histogenesis of bone including ossification.

The farthest or outermost projections of the body, such as the HAND and FOOT.

Resistance and recovery from distortion of shape.

The occupational discipline of the traditional Chinese methods of ACUPUNCTURE THERAPY for treating disease by inserting needles along specific pathways or meridians.

COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I.

Fibroblasts which occur in the CORNEAL STROMA.

Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.

Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).

Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

A salt-soluble precursor of elastin. Lysyl oxidase is instrumental in converting it to elastin in connective tissue.

The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.

Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.

An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

The middle germ layer of an embryo derived from three paired mesenchymal aggregates along the neural tube.

A mucopolysaccharide constituent of chondrin. (Grant & Hackh's Chemical Dictionary, 5th ed)

Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.

A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.

The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.

An enzyme oxidizing peptidyl-lysyl-peptide in the presence of water & molecular oxygen to yield peptidyl-allysyl-peptide plus ammonia & hydrogen peroxide. EC 1.4.3.13.

A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4.

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.

The application of knowledge to the food industry.

Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.

A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)

An extracellular endopeptidase of vertebrate tissues similar to MATRIX METALLOPROTEINASE 1. It digests PROTEOGLYCAN; FIBRONECTIN; COLLAGEN types III, IV, V, and IX, and activates procollagenase. (Enzyme Nomenclature, 1992)

The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)

Proteins prepared by recombinant DNA technology.

High molecular weight insoluble polymers which contain functional anionic groups that are capable of undergoing exchange reactions with cations.

The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)

Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.

A non-fibrillar collagen that forms a network of MICROFIBRILS within the EXTRACELLULAR MATRIX of CONNECTIVE TISSUE. The alpha subunits of collagen type VI assemble into antiparallel, overlapping dimers which then align to form tetramers.

Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.

Methods of preparing tissue for examination and study of the origin, structure, function, or pathology.

Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.

The least progressive form of SYSTEMIC SCLERODERMA with skin thickening restricted to the face, neck and areas distal to the elbows and/or knees, sparing the trunk. The CREST SYNDROME is a form of limited scleroderma.

High molecular weight, insoluble polymers which contain functional groups that are capable of undergoing exchange reactions (ION EXCHANGE) with either cations or anions.

Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.

The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.

A sulfated mucopolysaccharide initially isolated from bovine cornea. At least two types are known. Type I, found mostly in the cornea, contains D-galactose and D-glucosamine-6-O-sulfate as the repeating unit; type II, found in skeletal tissues, contains D-galactose and D-galactosamine-6-O-sulfate as the repeating unit.

Chronic inflammation and granuloma formation around irritating foreign bodies.

The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.

An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.

A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.

The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.

Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.

The restriction of the MOVEMENT of whole or part of the body by physical means (RESTRAINT, PHYSICAL) or chemically by ANALGESIA, or the use of TRANQUILIZING AGENTS or NEUROMUSCULAR NONDEPOLARIZING AGENTS. It includes experimental protocols used to evaluate the physiologic effects of immobility.

Established cell cultures that have the potential to propagate indefinitely.

Proteoglycans consisting of proteins linked to one or more CHONDROITIN SULFATE-containing oligosaccharide chains.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)

An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS.

A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. It regulates TRANSFORMING GROWTH FACTOR BETA and ACTIVIN signaling.

A fibrous cord that connects the muscles in the back of the calf to the HEEL BONE.

A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.

Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)

A disease characterized by bony deposits or the ossification of muscle tissue.

The part of the membranous labyrinth that traverses the bony vestibular aqueduct and emerges through the bone of posterior cranial fossa (CRANIAL FOSSA, POSTERIOR) where it expands into a blind pouch called the endolymphatic sac.

The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.

A porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates to the canal of Schlemm.

A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.

A member of the metalloproteinase family of enzymes that is principally responsible for cleaving FIBRILLAR COLLAGEN. It can degrade interstitial collagens, types I, II and III.

The physiological renewal, repair, or replacement of tissue.

The forces and principles of action of matter and energy.

A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (From Dorland, 27th ed)

Destruction of hyaline cartilage in the sigmoid notch of the human ulna. (1/1596)

In an ulna from an adolescent a fossa nudata divided the articular surface of the sigmoid notch into olecranon and coronoid areas. In the floor of the fossa a layer of loose avascular pannus covered a thin layer of articular cartilage. The pannus appeared to have been formed by removal of chondroitin from the cartilage, freeing the cells and unmasking the fibres. Probably the change followed loss of contact between the articular cartilages of the sigmoid notch and trochlea during postnatal growth. (+info)

Structural changes in intramuscular connective tissue during the fattening of Japanese black cattle: effect of marbling on beef tenderization. (2/1596)

We investigated changes in structures and mechanical properties of the intramuscular connective tissue during the fattening of Japanese Black steers, using the cell maceration method for scanning electron microscopy. During the early fattening period, from 9 to 20 mo of age, collagen fibrils of the endomysium in longissimus muscle associated more closely with each other, and collagen fibers in the perimysium increased in thickness and their wavy pattern became more regular. These changes were closely related to the increase in mechanical strength of the intramuscular connective tissue and resulted in a toughening of the beef during the period. The shear force value of longissimus muscle decreased after 20 mo of age, concomitantly with the rapid increase in the crude fat content. Scanning electron micrographs of the longissimus muscle dissected from 32-mo-old steers clearly showed that the adipose tissues were formed between muscle fiber bundles, that the honeycomb structure of endomysia was partially broken, and that the perimysium separated into thinner collagen fibers. In semitendinosus muscle, in which the crude fat content was lower (P<.05) than that in longissimus muscle, the structure of the intramuscular connective tissue remained rigid at 32 mo of age. The shear force value of the muscle increased even in the late fattening period, from 20 to 32 mo of age. Thus, the development of adipose tissues in longissimus muscle appears to disorganize the structure of the intramuscular connective tissue and contributes to tenderization of highly marbled beef from Japanese Black cattle during the late fattening period. (+info)

Relationship between development of intramuscular connective tissue and toughness of pork during growth of pigs. (3/1596)

We investigated changes in structures and properties of the endomysium and perimysium during development of semitendinosus muscle in relation to the increase in toughness of pork using samples from neonates to 55-mo-old pigs. The shear force value of pork increased linearly until 6 mo of age, and the rate of increase slowed down thereafter. The secondary perimysium thickened owing to an increase in the number and thickness of perimysial sheets consisting of collagen fibers, which became thicker and wavy with the growth of the pigs. This increase in thickness of the secondary perimysium was correlated significantly with the increase in the shear force value (r = .98). The endomysial sheaths became thicker and denser in the muscle of 6-mo-old pigs. Maturation of the endomysium was accompanied by hypertrophy of muscle fibers. The amount of heat-soluble collagen decreased almost linearly, indicating that nonreducible cross-links between collagen molecules were formed throughout chronological aging. We conclude that thickening of the perimysium is closely related to an increase in the toughness of pork during growth of pigs. (+info)

Interaction of Borrelia burgdorferi with peripheral blood fibrocytes, antigen-presenting cells with the potential for connective tissue targeting. (4/1596)

BACKGROUND: Borrelia Burgdorferi has a predilection for collagenous tissue and can interact with fibronectin and cellular collagens. While the molecular mechanisms of how B. burgdorferi targets connective tissues and causes arthritis are not understood, the spirochetes can bind to a number of different cell types, including fibroblasts. A novel circulating fibroblast-like cell called the peripheral blood fibrocyte has recently been described. Fibrocytes express collagen types I and III as well as fibronectin. Besides playing a role in wound healing, fibrocytes have the potential to target to connective tissue and the functional capacity to recruit, activate, and present antigen to CD4(+) T cells. MATERIALS AND METHODS: Rhesus monkey fibrocytes were isolated and characterized by flow cytometry. B. burgdorferi were incubated with human or monkey fibrocyte cultures in vitro and the cellular interactions analyzed by light and electron microscopy. The two strains of B. burgdorferi studied included JD1, which is highly pathogenic for monkeys, and M297, which lacks the cell surface OspA and OspB proteins. RESULTS: In this study, we demonstrate that B. burgdorferi binds to both human and monkey (rhesus) fibrocytes in vitro. This process does not require OspA or OspB. In addition, the spirochetes are not phagocytosed but are taken into deep recesses of the cell membrane, a process that may protect them from the immune system. CONCLUSIONS: This interaction between B. burgdorferi and peripheral blood fibrocytes provides a potential explanation for the targeting of spirochetes to joint connective tissue and may contribute to the inflammatory process in Lyme arthritis. (+info)

Connective tissues: matrix composition and its relevance to physical therapy. (5/1596)

In the last 2 decades, the understanding of CT structure and function has increased enormously. It is now clear that the cells of the various CTs synthesize a variety of ECM components that act not only to underpin the specific biomechanical and functional properties of tissues, but also to regulate a variety of cellular functions. Importantly for the physical therapist, and as discussed above, CTs are responsive to changes in the mechanical environment, both naturally occurring and applied. The relative proportions of collagens and PGs largely determine the mechanical properties of CTs. The relationship between the fibril-forming collagens and PG concentration is reciprocal. Connective tissues designed to resist high tensile forces are high in collagen and low in total PG content (mostly dermatan sulphate PGs), whereas CTs subjected to compressive forces have a greater PG content (mostly chondroitin sulphate PGs). Hyaluronan has multiple roles and not only provides tissue hydration and facilitation of gliding and sliding movements but also forms an integral component of large PG aggregates in pressure-resisting tissues. The smaller glycoproteins help to stabilize and link collagens and PGs to the cell surface. The result is a complex interacting network of matrix molecules, which determines both the mechanical properties and the metabolic responses of tissues. Patients with CT problems affecting movement are frequently examined and treated by physical therapists. A knowledge of the CT matrix composition and its relationship to the biomechanical properties of these tissues, particularly the predictable responses to changing mechanical forces, offers an opportunity to provide a rational basis for treatments. The complexity of the interplay among the components, however, requires that further research be undertaken to determine more precisely the effects of treatments on the structure and function of CTs. (+info)

Recombinant human type II collagens with low and high levels of hydroxylysine and its glycosylated forms show marked differences in fibrillogenesis in vitro. (6/1596)

Type II collagen is the main structural component of hyaline cartilages where it forms networks of thin fibrils that differ in morphology from the much thicker fibrils of type I collagen. We studied here in vitro the formation of fibrils of pepsin-treated recombinant human type II collagen produced in insect cells. Two kinds of type II collagen preparation were used: low hydroxylysine collagen having 2.0 hydroxylysine residues/1,000 amino acids, including 1.3 glycosylated hydroxylysines; and high hydroxylysine collagen having 19 hydroxylysines/1,000 amino acids, including 8.9 glycosylated hydroxylysines. A marked difference in fibril formation was found between these two kinds of collagen preparation, in that the maximal turbidity of the former was reached within 5 min under the standard assay conditions, whereas the absorbance of the latter increased until about 600 min. The critical concentration with the latter was about 10-fold, and the absorbance/microgram collagen incorporated into the fibrils was about one-sixth. The morphology of the fibrils was also different, in that the high hydroxylysine collagen formed thin fibrils with essentially no interfibril interaction or aggregation, whereas the low hydroxylysine collagen formed thick fibrils on a background of thin ones. The data thus indicate that regulation of the extents of lysine hydroxylation and hydroxylysine glycosylation may play a major role in the regulation of collagen fibril formation and the morphology of the fibrils. (+info)

Altered connective tissue in children with congenital dislocation of the hip. (7/1596)

The umbilical cord was employed as a source of collagen in 10 children with congenital dislocation of hip. The amount of collagen and its solubility were measured in slices of the cords and in the umbilical veins and compared with the values in normal subjects. Both the amount of collagen and its solubility were decreased in children with congenital dislocation of the hip. (+info)

Insulin regulation of amino acid transport in mesenchymal cells from avian and mammalian tissues. (8/1596)

Insulin regulation of amino acid transport across the cell membrane was studied in a variety of mesenchymal cell directly isolated from avian and mammalian tissues or collected from confluent cultures. Transport activity of the principal systems of mediation in the presence and absence of insulin was evaluated by measuring the uptake of representative amino acids under conditions approaching initial entry rates. Insulin enhanced the transport rate of substrate amino acids from the A system(alpha-aminoisobutyric acid, L-proline, glycine, L-alanine and L-serine) in fibroblasts and osteoblasts from chick-embryo tissues, in mesenchymal cells (fibroblasts and smooth muscle cells) from immature rat uterus, in thymic lymphocytes from young rats and in chick-embryo fibroblasts from confluent secondary cultures. In these tissues, the uptake of amino acid substrates of transport systems L and Ly+ (L-leucine, L-phenylalanine, L-lysine) was not affected by the presence of the hormone. No insulin control of amino acid transport was detected in chick-embryo chondroblasts and rat peritoneal macrophages. These observations identify the occurrence of hormonal regulatory patterns of amino acid transport for different mesenchymal cells types and indicate that these properties emerge early during cell differentiation. (+info)

... can be broadly classified into connective tissue proper, and special connective tissue. Connective tissue ... Connective tissue is one of the four primary types of animal tissue, along with epithelial tissue, muscle tissue, and nervous ... Fibromuscular tissue is made up of fibrous tissue and muscular tissue. New vascularised connective tissue that forms in the ... Other kinds of connective tissues include fibrous, elastic, and lymphoid connective tissues. Fibroareolar tissue is a mix of ...

https://en.wikipedia.org/wiki/Connective_tissue

A connective tissue nevus may be present at birth or appear within the first few years, is elevated, soft to firm, varying from ...

https://en.wikipedia.org/wiki/Connective_tissue_nevus

Mixed connective tissue disease - Mixed connective-tissue disease (MCTD) is a disorder in which features of various connective- ... A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology ... Merck Manual: Musculoskeletal and connective tissue disorders Merck Manual: Inherited connective tissue disorders Arthritis ... Undifferentiated connective tissue disease (UCTD) is a disease in which the body mistakenly attacks its own tissues. It is ...

https://en.wikipedia.org/wiki/Connective_tissue_disease

A connective tissue neoplasm or connective tissue tumor is a neoplasm arising from the tissues of the connective tissue. (Not ... all tumors in the connective tissue are of the connective tissue.) Zelger, Bernhard (2002). "Connective tissue tumors". Recent ... Tissues (biology), Connective and soft tissue neoplasms). ...

https://en.wikipedia.org/wiki/Connective_tissue_neoplasm

It is classified as either dense regular connective tissue or dense irregular connective tissue. Loose connective tissue "Blue ... Dense connective tissue, also called dense fibrous tissue, is a type of connective tissue with fibers as its main matrix ... TermsCells&Tissues/connective/dense/dense1 - Comparative Organology at University of California, Davis - "Connective tissue, ... Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets. ...

https://en.wikipedia.org/wiki/Dense_connective_tissue

... is a subset of connective tissue proper. Furthermore, areolar tissue is the same as loose connective ... Loose connective tissue, sometimes called areolar tissue, is a cellular connective tissue with thin and relatively sparse ... They join connective tissues to other tissues. Areolar tissue (/əˈriːələr/ or /ˌɛəriˈoʊlər, ˌær-/) is a common type of loose ... Areolar connective tissue holds organs in place and attaches epithelial tissue to other underlying tissues. It also serves as a ...

https://en.wikipedia.org/wiki/Loose_connective_tissue

... is a type of connective tissue with a network of reticular fibers, made of type III collagen ( ... Reticular connective tissue resembles areolar connective tissue, but the only fibers in its matrix are reticular fibers, which ... "Connective tissue, reticular (LM, Medium)" Histology at uwa.edu.au (Connective tissue). ... Reticular connective tissue is found around the kidney, liver, the spleen, and lymph nodes, Peyer' patches as well as in bone ...

https://en.wikipedia.org/wiki/Reticular_connective_tissue

... (also called mutable collagenous tissue) is a kind of connective tissue found in echinoderms (such as ... Connective tissue, including dermis, tendons and ligaments, is one of four main animal tissues. Usual connective tissue does ... This connective tissue is specific to echinoderms in which it works in posture maintenance and mechanical defense with low ... Catch connective tissue is found in all the extant classes of echinoderms. Sea lilies and feather stars: ligaments connecting ...

https://en.wikipedia.org/wiki/Catch_connective_tissue

DRCT is divided into white fibrous connective tissue and yellow fibrous connective tissue, both of which occur in two forms: ... Dense regular connective tissue (DRCT) provides connection between different tissues in the human body. The collagen fibers in ... "Dense regular connective tissue". www.pc.ctc.edu. Archived from the original on 2009-09-25. Retrieved 2009-10-16. "What Are ... Dense regular connective tissue has great tensile strength that resists pulling forces especially well in one direction. DRCT ...

https://en.wikipedia.org/wiki/Dense_regular_connective_tissue

... (UCTD) is a disease in which the body mistakenly attacks its own tissues. It is ... Connective tissue diseases, Systemic connective tissue disorders). ... August 2009). "Undifferentiated connective tissue disease: a seven-center cross-sectional study of 184 patients". Clinical ... June 2011). "Undifferentiated connective tissue disease presenting with prevalent interstitial lung disease: Case report and ...

https://en.wikipedia.org/wiki/Undifferentiated_connective_tissue_disease

... has fibers that are not arranged in parallel bundles as in dense regular connective tissue. ... Dense irregular connective tissue consists of mostly collagen fibers. It has less ground substance than loose connective tissue ... "Connective Tissue". Archived from the original on 2008-11-07. Retrieved 2008-11-27. "Dense irregular connective tissue". ... Fibroblasts are the predominant cell type, scattered sparsely across the tissue. This type of connective tissue is found mostly ...

https://en.wikipedia.org/wiki/Dense_irregular_connective_tissue

In dentistry, the subepithelial connective tissue graft (SECT graft, and sometimes referred to simply as a connective tissue ( ... describes how the individual who receives the graft is the same individual who provides the donor tissue. The connective tissue ... Because the connective tissue for the graft is transplanted without the superficial epithelium from the donor site, it is ... At the donor site, Edel described three methods for choosing and preparing the donor site to obtain connective tissue for the ...

https://en.wikipedia.org/wiki/Subepithelial_connective_tissue_graft

... is a rare condition, and often occurs on the upper or lower extremities. Involutional ...

https://en.wikipedia.org/wiki/Atrophic_connective_tissue_panniculitis

"Mixed Connective Tissue Disease, MCTD". The Free Dictionary by Farlex. Nevares AM, Larner R. "Mixed Connective Tissue Disease ( ... "Definition and diagnosis of mixed connective tissue disease". Alves, Marta (2020). ""Mixed connective tissue disease": a ... "Mixed Connective Tissue Disease (MCTD)". MedicineNet.com. Nevares AM, Larner R. "Mixed Connective Tissue Disease (MCTD): ... Connective tissue diseases, Disorders of fascia, Systemic connective tissue disorders, Autoimmune diseases). ...

https://en.wikipedia.org/wiki/Mixed_connective_tissue_disease

710 Diffuse diseases of connective tissue 710.0 Systemic lupus erythematosus 710.2 Sjögren's syndrome 710.3 Dermatomyositis ... Diseases of the Musculoskeletal System and Connective Tissue. It covers ICD codes 710 to 739. The full chapter can be found on ... 710.4 Polymyositis 710.5 Eosinophilia myalgia syndrome 710.9 Connective tissue disease, unspec. 711 Arthropathy associated with ... unspecified 729.3 Panniculitis unspecified 729.4 Fasciitis unspecified 729.5 Pain in limb 729.6 Foreign body in soft tissue ...

https://en.wikipedia.org/wiki/List_of_ICD-9_codes_710–739:_diseases_of_the_musculoskeletal_system_and_connective_tissue

Rubbelke DL (1999). "Connective Tissue Proper". Tissues of the Human Body: An Introduction. McGraw-Hill Companies. v t e (CS1 ... ISBN 978-1-118-34500-9. "Connective Tissue". Self Study Unit of the Basic Tissues. University of Ottawa. Archived from the ... Dense connective tissue has a smaller amount of ground substance compared to the fibrous material. The meaning of the term has ... Loose connective tissue is characterized by few fibers and cells, and a relatively large amount of ground substance. ...

https://en.wikipedia.org/wiki/Ground_substance

"Connective Tissue". Art Practical. Retrieved 2021-06-05.{{cite journal}}: CS1 maint: url-status (link) Mukherjee, Ranu (2019-07 ...

https://en.wikipedia.org/wiki/Ranu_Mukherjee

Connective Tissue Research. 25 (2): 103-119. doi:10.3109/03008209009006985. ISSN 0300-8207. PMID 2175692. Wikidata Q43601010. ...

https://en.wikipedia.org/wiki/Brigid_Heywood

Connective Tissue Research. 44 (1): 20-25. doi:10.1080/713713602. PMID 12952169. Pyura pachydermatina discussed in RNZ Critter ... Connective Tissue Research. 34 (4): 263-269. doi:10.3109/03008209609005270. PMID 9084635. "Pyura". Biosecurity in New Zealand. ... The tissues of this tunicate are strengthened by the presence of two types of spicules. In the blood vessels in the tunic there ... Aizenberg, J.; Weiner, S.; Addadi, L. (2003). "Coexistence of amorphous and crystalline calcium carbonate in skeletal tissues ...

https://en.wikipedia.org/wiki/Pyura_pachydermatina

Connective Tissue Research. 20 (1-4): 313-9. doi:10.3109/03008208909023902. PMID 2612162. Wozney JM, Rosen V, Celeste AJ, ... It is highly expressed in fractured tissues. BMP3 is hypermethylated in many cases of colorectal cancer (CRC) and hence along ... and tissue inhibitors in human fetal, adult, and osteoarthritic articular cartilage". Journal of Orthopaedic Research. 22 (6): ...

https://en.wikipedia.org/wiki/Bone_morphogenetic_protein_3

Okamoto O, Fujiwara S (2006). "Dermatopontin, a novel player in the biology of the extracellular matrix". Connective Tissue ... The extracellular matrix (ECM) is known as a non-cellular component that is found in all organs and tissues. The ECM provides ... The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is a component of the ... while in tissues, Fn perform as an activated and collected into the Fn matrix (a fibrillar structure) that discovered during ...

https://en.wikipedia.org/wiki/Dermatopontin

McKee MD, Nanci A (1996). "Osteopontin: an interfacial extracellular matrix protein in mineralized tissues". Connective Tissue ... Connective Tissue Research. 44 (Suppl 1): 33-40. doi:10.1080/03008200390152061. PMID 12952171. S2CID 29910722. Christensen B, ... The prefix osteo- indicates that the protein is expressed in bone, although it is also expressed in other tissues. The suffix - ... Da Silva AP, Pollett A, Rittling SR, Denhardt DT, Sodek J, Zohar R (September 2006). "Exacerbated tissue destruction in DSS- ...

https://en.wikipedia.org/wiki/Osteopontin

... and connective tissue (bone fibers). Scrutiny under the microscope further revealed that the putative dinosaur soft tissue had ... 2003). "Identification of Proteinaceous Material in the Bone of the Dinosaur Iguanodon". Connective Tissue Research. Milton ... After recovery, the tissue was rehydrated by the science team. When the fossilized bone was treated over several weeks to ... This included even more detailed tissue, down to preserved bone cells that seem to have visible remnants of nuclei and what ...

https://en.wikipedia.org/wiki/Dinosaur

Connective Tissue Research. 41 (1): 29-36. doi:10.3109/03008200009005639. ISSN 0300-8207. PMID 10826706. S2CID 34511081. ... This phenomenon was discovered in 1912, and the terminology was introduced in 1945, but it is with the development of tissue ... Weiss, Paul (December 1945). "Experiments on cell and axon orientation in vitro: The role of colloidal exudates in tissue ... Similarly, the collagen fibers present in collagen gels and soft tissues can influence cell alignment, providing the most ...

https://en.wikipedia.org/wiki/Contact_guidance

Boskey AL (2003). "Biomineralization: an overview". Connective Tissue Research. 44 (Supplement 1): 5-9. doi:10.1080/713713622. ... often to harden or stiffen existing tissues. Such tissues are called mineralized tissues. It is an extremely widespread ... Currey JD (December 1999). "The design of mineralised hard tissues for their mechanical functions". The Journal of Experimental ... Murdock DJ, Donoghue PC (2011). "Evolutionary origins of animal skeletal biomineralization". Cells Tissues Organs. 194 (2-4): ...

https://en.wikipedia.org/wiki/Biomineralization

C: Connective tissue. A dense subcutaneous layer of fat and fibrous tissue that lies beneath the skin, containing the nerves ... The 'danger area of the scalp' is the area of loose connective tissue. This is because pus and blood spread easily within it, ... L: The loose areolar connective tissue layer provides an easy plane of separation between the upper three layers and the ... A knife with multiple blades is used to remove tissue from donor areas. The removed tissue is then fragmented into smaller ...

https://en.wikipedia.org/wiki/Scalp

... with a specific interest in how the connective tissue of blood vessel walls changes with age. She carried out seminal work on ... Connective Tissue Research. 15 (1-2): 3-7. doi:10.3109/03008208609001966. ISSN 0300-8207. PMID 2944699. Rall, Jack A. (2018-04- ... an enzyme capable of degrading the protein elastin which gives tissues like veins their flexibility. She also contributed to ...

https://en.wikipedia.org/wiki/Ilona_Banga

Connective Tissue Research. 40 (1): 1-11. doi:10.3109/03008209909005273. PMID 10770646. Strober, Warren; Fuss, Ivan J. (May ... Both CD4+ and CD8 IL-17 producing T cells have been shown to cause aTH1, causing tissue inflammation and resulting in severe ... Cytokines derived from adipose tissue serve as remote regulators such as hormones. Studies have shown that TNF-α and IL-6 ... A proinflammatory cytokine causes hyperinflammation, the leading cause of lung tissue destruction in cystic fibrosis. With such ...

https://en.wikipedia.org/wiki/Inflammatory_cytokine

Boskey AL (2003). "Biomineralization: an overview". Connective Tissue Research. 44 Suppl 1 (1): 5-9. doi:10.1080/713713622. ... produced by epithelial tissues in most animals. Mucins' key characteristic is their ability to form gels; therefore they are a ... colon and other tissues. Mucins are also overexpressed in lung diseases such as asthma, bronchitis, chronic obstructive ...

https://en.wikipedia.org/wiki/Mucin

Connective Tissue Research. 44 (Suppl. 1): 41-46. doi:10.1080/03008200390152070. PMID 12952172. S2CID 2249126. Paul, Gregory S ... only noting on page 69 that there is no hard-tissue evidence for venom in stingray tails and platypus spurs. Elting and Goodman ...

https://en.wikipedia.org/wiki/Iguanodon

Together, they published a monograph on the vital staining of connective tissue cells. The discovery of Vitamin E came as a ... On the differential reaction to vital dyes exhibited by the two groups of connective-tissue cells. Washington, D.C.: Carnegie ... Herbert Mclean On the differential reactions to vital dyes exhibited by the two great groups of connective-tissue cells. ...

https://en.wikipedia.org/wiki/Katharine_Bishop

Development proceeds and the oogonia become fully surrounded by a layer of connective tissue cells (pre-granulosa cells). In ... There are also developments of other tissues from the mesonephric duct that persist, e.g. the development of the suspensory ... and the corpus spongiosum penis arise from the mesodermal tissue in the phallus; they are at first dense structures, but later ...

https://en.wikipedia.org/wiki/Development_of_the_reproductive_system

... can also present in the setting of nontraumatic inflammatory injury of auricular connective tissue such as in ... Consequently, the concave pinna fills with disorganized connective tissue. The cartilage then deforms and kinks, resulting in ... Risk of necrotic tissue is greatest when both posterior and anterior surfaces are involved, although posterior surface ... causing it to die and resulting in the formation of fibrous tissue in the overlying skin. As a result, the outer ear becomes ...

https://en.wikipedia.org/wiki/Cauliflower_ear

Peritendinous tissues become macroscopically thickened and new connective tissue adhesions occur. In paratenonitis, ... Soft tissue, Skeletal system, Tendons, All stub articles, Musculoskeletal disease stubs). ...

https://en.wikipedia.org/wiki/Paratenonitis

Sjorgen's syndrome not associated with other health problems or connective tissue diseases) is hyper-methylated at its CpG ... Studies have reported that: 1) the levels of CMTM5-v1 in the malignant tissues of patients with prostate cancer are lower than ... the levels in their nearby normal prostate gland tissues as well as in the tissues of patients with benign prostate hyperplasia ... 2) patients with lower prostate cancer tissue levels of CMTM5-v1 have higher prostate cancer Gleason scores and therefore ...

https://en.wikipedia.org/wiki/CKLF-like_MARVEL_transmembrane_domain-containing_5

... the connective tissue, blood and other non-fat content must be removed. It then must be coarsely grated. It must be ...

https://en.wikipedia.org/wiki/Suet

... are infections of skin and associated soft tissues (such as loose connective tissue and mucous membranes).[citation needed] ... Skin and skin structure infections (SSSIs), also referred to as skin and soft tissue infections (SSTIs), or acute bacterial ... microbiologic evaluation using tissue culture has been demonstrated to have high utility in guiding management decisions. There ... "Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases ...

https://en.wikipedia.org/wiki/Skin_and_skin_structure_infection

As tendons develop they lay down collagen, which is the main structural protein of connective tissue. As tendons pass near bony ... Tendons are cords of connective tissue attaching muscle to bone, cartilage or other tendons. They are a major contributor to ... In equine ovaries, unlike in humans, the vascular tissue is cortical to follicular tissue, so ovulation can only occur at an ... Scar tissue within the tendon decreases the overall elasticity in the damaged section of the tendon as well, causing an ...

https://en.wikipedia.org/wiki/Equine_anatomy

Connective/soft tissue tumors and sarcomas, All stub articles, Neoplasm stubs, Pathology stubs, Oncology stubs). ... They consist of epithelial tissue, and stromal or mesenchymal tissue. They may be benign or malignant. Examples include: ...

https://en.wikipedia.org/wiki/Fibroepithelial_neoplasm

... poses apply moderate stress to the connective tissues of the body-the tendons, fasciae, and ligaments-with the aim of ... These areas are especially rich in connective tissues, the "loading" of which (Yin Yoga teachers avoid the word "stretching") ... In the body, the relatively stiff connective tissues (tendons, ligaments, fascia) are considered yin, while the more mobile and ... Taoist-based practice targets the connective tissues, ligaments, joints and synovial fluid". Los Angeles Times. Pizer, Ann (17 ...

https://en.wikipedia.org/wiki/Yin_Yoga

... also known as hexabrachion-like protein is a glycoprotein that is expressed in connective tissues including skin, joints and ... miR-137 is epigenetically silenced in colorectal adenomatous tissues to the same extent as in colorectal cancer tissues, ...

https://en.wikipedia.org/wiki/MiR-137

... connective tissues in fishes and theropods or insect wings). Most of the osteological features of the holotype became apparent ... stagnation and the action of microbial mats in the locality that have yielded a wide variety of examples of soft-tissue ... "The mineralization of dinosaur soft tissue in the Lower Cretaceous of Las Hoyas, Spain", Journal of the Geological Society, vol ...

https://en.wikipedia.org/wiki/Eoalulavis

Occasionally, this inflammation can cause scar tissue to form on Glisson's capsule, a thin layer of connective tissue ...

https://en.wikipedia.org/wiki/Fitz-Hugh–Curtis_syndrome

Myofascial pain is pain in muscles or fascia (a type of connective tissue that surrounds muscles). It can occur in distinct, ... connective tissue) constrictions. It can appear in any body part. Symptoms of a myofascial trigger points include: focal point ... such as connective tissue disease, can cause MPS. Poor posture and emotional disturbance might also instigate or contribute to ... Soft tissue disorders, Ailments of unknown cause, Disorders of fascia, Pain, Chronic pain syndromes, Rheumatology, Urologic ...

https://en.wikipedia.org/wiki/Myofascial_pain_syndrome

The connective tissue between the lobes of the anthers extends upward to form a disc-shaped cap. Its flowers have 2-7 carpels ...

https://en.wikipedia.org/wiki/Hexalobus_monopetalus

... syndrome Congestive heart failure Conjunctivitis ligneous Conjunctivitis with pseudomembrane Conjunctivitis Connective tissue ... Cohen syndrome Camfak syndrome Campomelia Cumming type Camptobrachydactyly Camptocormism Camptodactyly fibrous tissue ...

https://en.wikipedia.org/wiki/List_of_diseases_(C)

Connective tissue: The term used by Kornheiser to describe the robust community and connections created by the show in an ...

https://en.wikipedia.org/wiki/The_Tony_Kornheiser_Show

... mixed connective tissue disease, poststreptococcal glomerulonephritis, rheumatoid arthritis, and systemic sclerosis. Less ...

https://en.wikipedia.org/wiki/Pulmonary-renal_syndrome

... is an association between familial thoracic aortic aneurysm and Marfan syndrome as well as other hereditary connective tissue ...

https://en.wikipedia.org/wiki/Familial_thoracic_aortic_aneurysm

The sponge body is mostly a connective tissue; the mesohyl, over which are applied epithelioid monolayers of cells, the outer ...

https://en.wikipedia.org/wiki/Choanoderm

... spindle-shaped or star-shaped fibroblasts and ectatic blood vessels in a dense collagen fiber connective tissue background. In ... Sobanko JF, Dagum AB, Davis IC, Kriegel DA (June 2007). "Soft tissue tumors of the hand. 1. Benign". Dermatologic Surgery. 33 ( ... The treatment of KTs has varied depending on their size, numbers, locations, symptoms, damage to tissues, and disfiguring ... Paral KM, Petronic-Rosic V (2017). "Acral manifestations of soft tissue tumors". Clinics in Dermatology. 35 (1): 85-98. doi: ...

https://en.wikipedia.org/wiki/Koenen's_tumor

As well as glands, the seminal vesicles contain smooth muscle and connective tissue. This fibrous and muscular tissue surrounds ... They do not cause elevation of tumour markers, and are usually diagnosed based examination of tissue that has been removed ... Adenocarcinomata are usually diagnosed after they are excised, based on tissue diagnosis. Some produce the tumour marker Ca-125 ... The tissue of the seminal vesicles is full of glands, spaced irregularly. ...

https://en.wikipedia.org/wiki/Seminal_vesicles

The segments are separated from each other by layers of connective tissue that forms them into discrete anatomical and ...

https://en.wikipedia.org/wiki/Bronchopulmonary_segment

Skeletal muscle includes skeletal muscle fibers, blood vessels, nerve fibers, and connective tissue. Skeletal muscle is wrapped ... Striated muscle tissue is a muscle tissue that features repeating functional units called sarcomeres. The presence of ... Unlike skeletal and cardiac muscle tissue, smooth muscle tissue is not striated since there are no sarcomeres present. Skeletal ... Striated muscle tissue has more mitochondria than smooth muscle. Both smooth muscle cells and cardiac muscle cells have a ...

https://en.wikipedia.org/wiki/Striated_muscle_tissue

... muscle or connective tissue are intact, a skin graft can be used. A skin graft needs healthy, vascularised tissue beneath it to ... The large blood vessels and nerves of the scalp don't pierce this layer.Loose connective tissue between the periosteum and the ... If this is not possible without tension, the surrounding loose connective tissue can be undermined to attain more mobility. ... Thus, if vascular and nervous anatomy is respected, the skin, subcutaneous tissue and galea aponeurotica can be lifted off the ...

https://en.wikipedia.org/wiki/Scalp_reconstruction

... before any genetic or morphological criteria were put in place for bone marrow or connective tissues. Osteoprogenitor cells can ... These cellular units will then develop into skeletal and other tissues, such as cartilage, tendon, ligament and muscle tissue.[ ... Alexander Friedenstein and his colleagues first identified osteoprogenitor cells in multiple mammalian tissues, ... Tissue Engineering Part A. 14 (9): 1573-80. doi:10.1089/ten.tea.2008.0113. PMID 18774911. Downey, CM; Horton CR; Carlson BA; ...

https://en.wikipedia.org/wiki/Osteochondroprogenitor_cell

... is caused by a loss of elasticity in the connective tissue supporting the structure of the front portion of the ... It can also be observed in various hereditary connective tissue disorders, including classical Ehlers-Danlos syndrome and cutis ... In dermatochalasis, the excess tissues hangs down, over the front edge of the eyelid. The excess tissue can sometimes obstruct ... This is observed as the presence of bulges (fat pads) in the soft tissue of the baggy eyes. ...

https://en.wikipedia.org/wiki/Dermatochalasis

Secondly, the beef's natural enzymes break down the connective tissue in the muscle, which leads to more tender beef. The ... in order to break down the connective tissue within the meat. Dry-aged beef is beef that has been hung or placed on a rack to ...

https://en.wikipedia.org/wiki/Beef_aging

"The subepithelial connective tissue pedicle graft combined with the coronally advanced flap for restoring missing papilla: A ... 3. Gingiva biotype; thick and thin tissues often respond differently to inflammation and trauma, thin gingiva is more liable to ...

https://en.wikipedia.org/wiki/Angularis_nigra

Intermediate weapons - an amount of force that would have a high probability of causing soft connective tissue damage or bone ... the amount of force that has a probability of causing soft connective tissue damage or bone fractures or irritation of the skin ... a level of force that has a low probability of causing soft connective tissue damage or bone fractures. This would include ...

https://en.wikipedia.org/wiki/Use_of_force_continuum

Large search returns make our pages slow to load. Therefore, some functionality has been disabled until you refine your search to bring the number of returned assay results under TBD ...

https://www.informatics.jax.org/gxd/summary?markerMgiId=MGI:3649881&structureID=EMAPA:35251&structure=connective%20tissue&tab=stagegridtab

There are over 200 disorders that affect connective tissues. Examples include cellulitis, scars, and osteogenesis imperfecta. ... ClinicalTrials.gov: Connective Tissue Diseases (National Institutes of Health) * ClinicalTrials.gov: Mixed Connective Tissue ... Cartilage and fat are types of connective tissue.. Over 200 disorders that impact connective tissue. There are different types: ... Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular ...

https://medlineplus.gov/connectivetissuedisorders.html

Drs Jeffrey Swigris and Sonye Danoff discuss connective tissue disease-related interstitial lung disease (CTD-ILD) to provide ... Connective Tissue Disease-Interstitial Lung Disease. Jeffrey J. Swigris, DO; Sonye K. Danoff, MD, PhD ... Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease: The Pulmonologists Point of View ... Cite this: Connective Tissue Disease-Interstitial Lung Disease - Medscape - Apr 04, 2023. ...

https://www.medscape.com/viewarticle/982421

disease and has_disease_location some (connective tissue or part of some connective tissue) ... connective tissue disorder this grouping excludes some diseases affecting tissues classically considered to be connective ... connective tissue disease. Go to external page http://www.ebi.ac.uk/efo/EFO_1001986 Copy ... A disease involving the connective tissue. [ https://orcid.org/0000-0002-6601-2165 ] ...

https://www.ebi.ac.uk/ols/ontologies/efo/terms?short_form=EFO_1001986

Mixed connective-tissue disease (MCTD) is a disorder with features of systemic sclerosis (SSc), lupus erythematosus, and ... Dermatologic Manifestations of Mixed Connective Tissue Disease) and Dermatologic Manifestations of Mixed Connective Tissue ... Dermatologic Manifestations of Mixed Connective Tissue Disease * Sections Dermatologic Manifestations of Mixed Connective ... Does mixed connective tissue disease exist? Yes. Rheum Dis Clin North Am. 2005 Aug. 31(3):411-20, v. [QxMD MEDLINE Link]. ...

https://emedicine.medscape.com/article/1066445-differential

Connective tissue, a fibrous tissue that encompasses ligaments, tendons, joint capsules and muscle fascia is often plagued by ... CONNECT 2017: International Congress on Connective Tissue. Tendons, Ligaments, Cartilage and Fascia Ulm University 08/26/2019 ... While fascia may be at the forefront of the conference, the intricacies of other connective tissue types - ligaments, tendons, ... The conference will see the coming together of many renowned connective tissue specialists and respected persons from the world ...

https://www.uni-ulm.de/en/med/medical-faculty/news-detail/article/connect-2017-international-congress-on-connective-tissue-tendons-ligaments-cartilage-and-fascia/

When these connective tissues become inflamed, this can harm the proteins and surrounding areas of the body. This is known as a ... Connective tissues hold the structures of the body together. They are made up of two different proteins, collagen and elastin. ... When these connective tissues become inflamed, this can harm the proteins and surrounding areas of the body. This is known as a ... The cause of connective tissue disorders is not always known. Some are caused by a genetic component, while others can be ...

https://www.cedars-sinai.org/health-library/diseases-and-conditions/c/connective-tissue-disorders.html

I am prone to writing scenes at the end of works in progress and then filling in connective tissue later, if at all. So far ... Although so far the connective tissues is a lot of talking-about-what-we-are-going-to-do and not many swashes have been buckled ...

http://www.redwombatstudio.com/2012/11/02/connective-tissue/

Reticular connective tissue - histology slide This is a histology slide of reticular connective tissue. Reticular connective ... tissue forms the framework for most of the lymphoid organs.. Histology slide courtesy of Beatrice Public Schools. ...

https://histology-world.com/photoalbum/displayimage.php?album=topn&cat=0&pid=1536

Learn about the veterinary topic of Connective Tissue Tumors in Animals. Find specific details on this topic and related topics ... Adipose Tissue Tumors Lipomas are benign tumors of adipose tissue, perhaps more accurately characterized as hamartomas. They ... Fibrosarcomas with abundant interstitial proteoglycans (connective tissue mucins) are called myxosarcomas or myxofibrosarcomas ... Lipomas with an abundant connective tissue stroma (fibrolipomas), cartilaginous stroma (chondrolipomas), or a prominent ...

https://www.merckvetmanual.com/veterinary/integumentary-system/tumors-of-the-skin-and-soft-tissues/connective-tissue-tumors-in-animals

2022 Genetic Support Network of ...

https://www.gsnv.org.au/tags/connective-tissue-disorders/

... trained connective tissue glides easily and is elastic. This helps the body to recover quickly and protects it from injury. ... What is connective tissue? Our connective tissue, also called fascia tissue, consists of an elastic material that runs through ... Strengthen your con-nective tissue: why its worth it & how it works. Strong, trained connective tissue glides easily and is ... What does strong connective tissue achieve?. Strong, trained connective tissue glides easily and is elastic. It protects the ...

https://www.css.ch/en/private-customers/my-health/physical-health/bones-muscles/strengthen-connective-tissue.html

... "connective tissue" is.. Connective tissue is one of the four general classes of biological tissues-the others being epithelial ... At PHRC, we refer to the treatment of connective tissue restriction as "connective tissue manipulation." However, the common ... Bones, ligaments, tendons, and cartilage are all considered connective tissue. However, the type of connective tissue that ... muscular, and nervous tissues. The job of connective tissue is to support, connect, or separate different types of tissue and ...

https://pelvicpainrehab.com/female-pelvic-pain/1642/pelvic-pain-pt-the-role-of-connective-tissue-manipulation/

... Food and Nutrition Sciences,06,1522 ... visible connective tissues) were found on M. longissimus thoracis (p = 0.005). On touch, M. longissimus thoracis was considered ... the presence of nerves may be related to connective tissue content (correlation: −0.21) and collagen solubility (correlation: − ... 6. Purslow, P.P. (2005) Intramuscular Connective Tissue and Its Role in Meat Quality. Meat Science, 70, 435-447. http://dx.doi. ...

https://file.scirp.org/Html/5-2701716_61892.htm

I had some early symptoms of Marfan Syndrome, a disease that affects connective tissues and can be fatal if there is leakage to ... a connective tissue disorder. The diagnosis was based on physical observations of Lincoln: the fact that he was much taller ... Peter Roe and the tissues are strong, the aortic rout is clear and my heart is in good shape - as long as my Baltimore Ravens ... Actor With Marfans Connective Tissue Disease Actor With Marfans Connective Tissue Disease ...

https://www.dinet.org/forums/topic/11903-actor-with-marfans-connective-tissue-disease/

Neoliberalism as the Connective Tissue of Contemporary Capitalism

http://siba-ese.unisalento.it/index.php/paco/article/view/16306/14057

Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - Part 1. Posted on ... Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - Part 2 → ... Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - Part 2 → ... 25 responses to "Like a Wasting Disease, Neoliberals, Libertarians & the Right are Eating Away Societys "Connective Tissue" - ...

https://neweconomicperspectives.org/2013/05/like-a-wasting-disease-neoliberals-libertarians-the-right-are-eating-away-societys-connective-tissue-part-1.html?shared=email&msg=fail

T1 - Ulcerative pyoderma gangrenosum in mixed connective tissue disorder. T2 - A rare association and role of azathioprine in ... Ulcerative pyoderma gangrenosum in mixed connective tissue disorder: A rare association and role of azathioprine in the ... Ulcerative pyoderma gangrenosum in mixed connective tissue disorder: A rare association and role of azathioprine in the ... Ulcerative pyoderma gangrenosum in mixed connective tissue disorder : A rare association and role of azathioprine in the ...

https://mayoclinic.pure.elsevier.com/en/publications/ulcerative-pyoderma-gangrenosum-in-mixed-connective-tissue-disord

Connective tissue imaged using the CFI Plan Apochromat Lambda D 40XC objective. ... CFI Plan Apochromat Lambda D Series - Connective tissue. Request Information Connective tissue. Connective tissue imaged using ...

https://www.microscope.healthcare.nikon.com/gallery-items/cfi-plan-apochromat-lambda-d-series-connective-tissue%20.gallery-item-entry

Neural tissue. Connective tissue. Along with epithelial tissue, muscle tissue, and nervous tissue, connective tissue is one of ... CBSE NCERT Notes Class 9 Biology Tissues - ExamFear. Class 9 Biology Tissues Connective Tissues CONNECTIVE TISSUES It protects ... Connective Tissues - General Biology. ous connective tissues. As you observe each tissue, look for its special distinguishing ... Notes of Ch 6 Animal Tissues, Class 9th Science. Aug 16, 2017·Connective Tissue. → The cells of the connective tissue are ...

https://www.geertroovers.nl/tissue_en/1628.html

A connective tissue disorder targets the bodys connective tissues, which are the structural materials (mainly the proteins, ... With a connective tissue disease, these proteins are injured by inflammation and can affect the skin, joints, bones, heart, ... Connective tissue disorders that directly affect the skin include the following:. Lupus erythematosus is an autoimmune disease ... Overview: What is a Connective Tissue Disorder? The information in this section has been gathered from existing peer-reviewed ...

https://canadianskin.ca/connective-tissue-disorders

tissue res. Outras Variações. 1. Connective tissue research (Online), 1607-8438. 2. Connective tissue research (CD-ROM), 1026- ... Connective tissue research.-- Vol.1 (1972) -.-- London ISSN 0300-8207. Título Abreviado. Connect. ...

http://portalrev.enfermagem.bvs.br/index.php?mfn=13242&holding_code=398&about=collection%E2%8C%A9=es

Rare Autoimmune/Complex Connective Tissue Diseases ] [ Rare Hereditary Connective Tissue Diseases ] [ Standardization Of Care ... Rare Autoimmune/Complex Connective Tissue Diseases ] [ Rare Hereditary Connective Tissue Diseases ] [ Standardization Of Care ... Rare Autoimmune/Complex Connective Tissue Diseases ] [ Rare Hereditary Connective Tissue Diseases ] [ Standardization Of Care ... Keywords : [ Complex Connective Tissue Diseases ] [ Education ] [ Hta ] [ Knowledge Improvement ] [ Patient Empowerment ] [ ...

https://webgate.ec.europa.eu/chafea_pdb/health/projects/keyword/1868/

It provides structural frame work and gives support to different tissues forming organs. ... It is one of the most abundant and widely distributed tissue. ... i. Connective tissue proper. Connective tissue proper consist ... Fluid connective tissue. The blood and the lymph are the fluid connective tissues which link different parts of the body. The ... Dense Connective Tissue. It is a fibrous connective tissue densely packed with fibres and fibroblasts. It is the principal ...

https://www.brainkart.com/article/Connective-Tissue_39906/

Connective tissue nevi are hamartomas in which one or several components of the dermis is altered. Lesions in which collagen ... encoded search term (Connective Tissue Nevus) and Connective Tissue Nevus What to Read Next on Medscape ... Connective Tissue Nevus Workup. Updated: Jan 09, 2023 * Author: Steven Brett Sloan, MD; Chief Editor: Dirk M Elston, MD more... ... Fibroblastic connective tissue nevus: a rare cutaneous lesion analyzed in a series of 25 cases. Am J Surg Pathol. 2012 Oct. 36 ...

https://emedicine.staging.medscape.com/article/1056490-workup

Duggal L, Bharija SC, Vasdev N. Connective tissue lipoatrophic panniculitis. Journal of the Association of Physicians of India ...

https://imsear.searo.who.int/handle/123456789/91559?locale=es

Palavras-chave : subepithelial connective tissue graft; marginal tissue recession; root coverage.. · texto em Inglês · pdf em ... Subepithelial connective tissue graft: a case report. RSBO (Online) [online]. 2011, vol.8, n.3, pp. 357-362. ISSN 1984-5685. ... originating from the connective tissue of both the periosteum and flap. Case report and conclusion: The authors reported a ... show great predictability of total coverage when the technique of subepithelial connective tissue graft is used. This technique ...

http://revodonto.bvsalud.org/scielo.php?script=sci_abstract&pid=S1984-56852011000300020&lng=pt&nrm=iso&tlng=en

http://www.staging.medscape.com/viewarticle/982421

Musculoskeletal and Connective Tissue: Myositis/polymyositis, rhabdomyolysis (and associated sequelae, including renal failure ... Immune-mediated adverse reactions, which may be severe or fatal, can occur in any organ system or tissue, can affect more than ...

https://www.merck.com/news/results-from-pivotal-phase-3-keynote-775-study-309-trial-of-keytruda-pembrolizumab-plus-lenvima-lenvatinib-in-advanced-endometrial-carcinoma-published-in-the-new-england-journal-of-med/

Tags Connective cells, Connective Tissue, function of connective tissue, Types of connective tissue 2 Comments. ... Unlike epithelial tissue, connective tissue typically has cells scattered throughout the matrix. Connective tissue is one … ... Types of connective tissue. Connective Tissue , Components, Function, Types. February 10, 2022. February 9, 2022. by Shreya ...

https://biology.edu-mate.com/tag/types-of-connective-tissue/

Over 200 disorders that impact connective tissue. (medlineplus.gov)
Symptoms of connective tissue disorders can vary depending on the affected areas. (cedars-sinai.org)
The cause of connective tissue disorders is not always known. (cedars-sinai.org)
Because connective tissue disorders can have symptoms similar to other conditions, diagnostic tests will help rule out other causes and confirm a diagnosis. (cedars-sinai.org)
There are several disorders that can directly affect the various connective tissues of the body. (factdr.com)
This a group of disorders of the connective tissue that arise as a result of defective mutations in the genes. (factdr.com)
Consider phospholipidosis as a possible cause of renal injury in patients with underlying connective tissue disorders. (nih.gov)
There are over 200 disorders that impact connective tissue. (ezdoctor.com)
Injuries can cause connective tissue disorders, such as scars. (ezdoctor.com)
Collagen Vascular Lung Disease Collagen vascular or connective tissue disorders are a group of autoimmune diseases in which antibodies attack the body's own organs and systems. (stevefrithphotography.com)
Connective tissues diseases (CTDs) are a heterogeneous group of disorders that share certain clinical characteristics and disturbed immunoregulation. (archivesofmedicalscience.com)
The rheumatological heritable disorders of connective tissue. (bvsalud.org)
Although not fully characterized, the known risk factors for P. jirovecii infection include impaired immunity because of HIV infection, hematologic malignancies, and connective tissue disorders ( 6 ). (cdc.gov)

Connective tissue, a fibrous tissue that encompasses ligaments, tendons, joint capsules and muscle fascia is often plagued by injury. (uni-ulm.de)
Where is the dense fibrous tissue found? (businessplaners.com)

While fascia may be at the forefront of the conference, the intricacies of other connective tissue types - ligaments, tendons, joint capsules and cartilage - will also be appreciated. (uni-ulm.de)
Our connective tissue, also called fascia tissue, consists of an elastic material that runs through the entire body and encases organs, tendons, ligaments and muscles. (css.ch)
This tissue is found in the dermis, in the fibrous capsule that surrounds the organs, in the sheaths of tendons and nerves, in the periosteum. (businessplaners.com)
A daily intake of collagen peptides for the entire body, with a special focus on joints, body tissues, tendons/ligaments and muscles. (fxsupplements.ie)
A connective tissue disease is one that affects tissues such as skin, tendons, and cartilage. (nih.gov)
Many studies have shown that WBC can improve the circulation in the skin as well as in the connective tissues, tendons, joints, and muscles. (onlinecancerguide.com)

A connective tissue disorder targets the body's connective tissues, which are the structural materials (mainly the proteins, collagen and elastin) that hold the cells of the body together. (canadianskin.ca)
Scleroderma results from overproduction and accumulation of collagen, a fibrous protein that makes up the connective tissues in the body. (canadianskin.ca)
Connective tissue proper consist of collagen bres, elastin bres and broblast cells. (brainkart.com)
Put simply, it's collagen acting as connective tissue. (ashleyblackguru.com)
By working all of your muscles, bones, and connective tissue in proper alignment, you will rebuild the collagen fibers of your fascia that will give you a bounce in your step. (essentricstv.com)
The majority of the body's proteins are composed of collagen, elastin, and other connective tissue components. (drrathresearch.org)
Changes of the peri-implant soft tissue thickness after grafting with a collagen matrix. (straumann.com)
Vertical soft tissue augmentation with porcine-derived collagen matrix membrane. (straumann.com)
Soft tissue volume alterations after connective tissue grafting at teeth: the subepithelial autologous connective tissue graft versus a porcine collagen matrix - a pre-clinical volumetric analysis. (straumann.com)
Biodegradation pattern and tissue integration of native and cross-linked porcine collagen soft tissue augmentation matrices - an experimental study in the rat. (straumann.com)
according to the National Institutes of Health , it also works as an antioxidant, aids in wound healing and is vital in collagen and connective tissue formation. (nwahomepage.com)

Treatments will vary depending on the type of connective tissue disorder diagnosis the patient receives. (cedars-sinai.org)
However, the type of connective tissue that we're interested in in the context of pelvic pain is known as "loose connective tissue. (pelvicpainrehab.com)
What type of connective tissue firmly inserts muscles to bones? (businessplaners.com)
Mixed connective tissue disease (MCTD) is a type of connective tissue regards to clinical and imaging features, it can have significant overlap with other connective tissue diseases such as systemic lupus erythematosus and scleroderma is therefore classified as a type of overlap syndrome and at times it even comes under debate as to whether MCTD should exist as a distinct. (stevefrithphotography.com)

Cartilage and fat are types of connective tissue. (medlineplus.gov)
5. Adipose tissue is also known as: fat cartilage Tissues MCQ Class 9 Science Chapter 6 Simple epithelial tissues are generally classified by the shape of their cells. (geertroovers.nl)
The supportive tissues include Cartilage and Bone. (brainkart.com)
Examples of connective tissues include cartilage, adipose tissue (fat), blood and bone. (factdr.com)
It can exist in liquid form (as in the plasma of blood), gelatinous (in areolar tissue), rubbery (in cartilage) or rigid form (as in bone). (factdr.com)

His contribution has captivated many in sports medicine, causing them to appreciate the role of fascia - the collagenous tissue found around and between muscles - in muscular injury and pain. (uni-ulm.de)
Events include expertly guided workshops on the diagnosis of connective tissue injury via new imaging methods, and fascia-centered coaching on running techniques, rehabilitation and physical therapy. (uni-ulm.de)
When in good condition, the fascia tissue around the muscles has a slightly undulating form. (css.ch)
When the fascia tissue can no longer fulfil its purpose, we speak of a weakness of the connective tissue. (css.ch)
Yet fascia training consists of much more: holistic stretching and mobilisation exercises are an important part of keeping the fascia tissue pliable. (css.ch)
This self-massage with either a fascia ball or roller has a similar effect to lymphatic drainage: it squeezes fluid out of the tissue. (css.ch)
And contrary to popular belief, your fascia isn't just soft tissue that just surrounds these areas like sausage casing-it is INSIDE them, too. (ashleyblackguru.com)
Fascia forms connective tissue, reacts to trauma, acts as a communication system, stores fluid, acts as a delivery system, transfers electrical energy, and functions as long-term storage for compounds both good and bad. (ashleyblackguru.com)
While this tightness is a protective measure that prevents you from further injuring yourself, tight fascia tissue can cause problems and limit your range of motion. (ashleyblackguru.com)
What is connective tissue/fascia? (bycuram.com)
Over the past decade, many anatomical studies have focused on the connective tissues of the human body, specifically the fascia. (seminarsforhealth.ca)
Fascia differs as a tissue type and can be quite dense in areas. (seminarsforhealth.ca)
Acupuncture causes changes in the fascia, which is the connective tissue that covers your muscles and bones. (cancer.net)

This is a histology slide of reticular connective tissue. (histology-world.com)
Reticular connective tissue forms the framework for most of the lymphoid organs. (histology-world.com)

The job of connective tissue is to support, connect, or separate different types of tissue and organs. (pelvicpainrehab.com)
Connective tissue can become restricted as a result of dysfunction in underlying muscle, nerves, joints and organs. (pelvicpainrehab.com)
On top of all of that, it's hypothesized that restricted connective tissue can cause referred pain-including pain to organs (think bladder in the case of pelvic pain)- via the central nervous system. (pelvicpainrehab.com)
Semantics aside, to fully treat connective tissue restriction, a PT has to normalize its mobility, improve circulation to the area, reduce hypersensitivity, and minimize the negative reflexive effects on surrounding muscles, nerves, and organs. (pelvicpainrehab.com)
3. Reticular fibers -provide a network to support blood vessels and support soft tissue of organs.Tissues Class 9 Notes - Chapter 6 Important Points To KnowCBSE Class 9 Science Notes on Tissues. (geertroovers.nl)
It provides structural frame work and gives support to different tissues forming organs. (brainkart.com)
The main function of the connective tissue is binding, supporting and packing together different organs of the body. (brainkart.com)
They are found in subcutaneous tissue, between internal organs around the heart and kidneys. (brainkart.com)
Bones support and protect soft tissues and organs. (brainkart.com)
The role of connective tissue, as the name suggests, is to bind, support and connect other tissues and organs together. (factdr.com)
These three components come together to form the glue that provides the extracellular matrix for other tissues and organs. (factdr.com)
Since connective tissues form the structural framework within our bodies, diseases affecting them will also have an impact on organs and other tissues associated with them. (factdr.com)
Other symptoms of Carney complex depend on the location of tumors, their size, and how the tumors affect the function of body organs and tissues. (nih.gov)
Marfan syndrome is a genetic disorder that affects the body's ability to make healthy connective tissue, which supports the bones, muscles, organs, and tissues in your body. (nih.gov)
Organs and tissues exposed to the external environment such as the gut have the highest density of mast cells. (hackyourgut.com)
This is an obstetrician-gynecologist with additional training in problems that affect the pelvic floor - the network of muscles, ligaments, connective tissue and nerves that helps support and control the bladder and other pelvic organs. (drugs.com)

Sixteen consecutive patients with connective tissue diseases were included in the study. (cdriadvlkn.org)
Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. (stevefrithphotography.com)

The growth plate is the area of tissue near the ends of long bones in children and teens that determines what length and shape the bone will be once it is done growing. (nih.gov)
Minerals and vitamins are important for the development and maintenance of bones and tissues, the production of milk in mares, and the regulation of basic body functions. (bestfriendequine.com)
Strengthening the joints, spine and building strong bones, while helping to form connective tissue. (hempusa.org)

Example questions to be discussed around include: What specific processes are in action during inflammatory processes in muscular connective tissues? (uni-ulm.de)
Connective tissue is one of the four general classes of biological tissues-the others being epithelial, muscular, and nervous tissues. (pelvicpainrehab.com)
Muscular tissue. (geertroovers.nl)
The four main types are epithelial, muscular, connective and nervous tissues. (factdr.com)
A pleasant, strong pressure and a deep, stroking massage stretches and opens the connective tissue, releasing deep-seated muscular tension and myogelosis. (thegeorge-hotel.de)

Epithelial tissue. (geertroovers.nl)
Along with epithelial tissue, muscle tissue, and nervous tissue, connective tissue is one of the four essential forms of animal tissue. (geertroovers.nl)
The tissue which has minimum intercellular space is epithelial tissue and connective tissue has largest intercellular spaces. (geertroovers.nl)
The epithelial tissue has great regeneration power and it is the first evolved tissue. (geertroovers.nl)
Unlike epithelial tissue, connective tissue typically has cells scattered throughout the matrix. (edu-mate.com)

Overlapping criteria for diagnosis of mixed connective tissue disease (MCTD) have been published by Sharp, Alarcón-Segovia, Kasukawa, and Kahn. (medscape.com)
2019 Diagnostic criteria for mixed connective tissue disease (MCTD): From the Japan research committee of the ministry of health, labor, and welfare for systemic autoimmune diseases. (medscape.com)
We described a 69-year-old woman with neurological manifestations due to mixed connective tissue disease (MCTD). (who.int)

In just 30 minutes you'll dispel any feelings of stiffness or "locked down" muscles and connective tissue. (essentricstv.com)
In contrast, many Western practitioners view the acupuncture points as places to stimulate nerves, muscles and connective tissue. (boonechamber.com)

Marfan syndrome an inherited disorder of connective tissue occurring once in every 10,000 to 20,000 individuals. (genome.gov)

This is known as a connective tissue disorder. (cedars-sinai.org)
Exposed root surfaces can be treated with a gum grafting procedure, also known as a connective tissue graft, at the affected site. (blackbeagledds.com)

Adipose tissue is the aggregation of fat cells or adipocytes and serves as fat reservoir. (brainkart.com)
Connective tissues are classified on the basis of the chemical-physical nature of the intercellular matrix that compose them: … Together with the adipose tissue, it forms the subcutaneous layer. (businessplaners.com)

It is a fluid connective tissue which is composed of the matrix called P lasma and formed elements . (aakash.ac.in)
In this fluid connective tissue, the blood cells move in a fluid matrix called plasma. (brainkart.com)

Loose connective tissue is aptly named because its fibers are randomly arranged and there's lots of space between the cells, which makes it THE ideal tissue for cushioning and protecting. (pelvicpainrehab.com)
Fibers of connective tissue: 1. (geertroovers.nl)
Fascial fibers form a thin casing of protective tissue that surrounds every system in your body. (ashleyblackguru.com)
Loose connective tissue is characterized by the presence of numerous cells with variable typology and by an amorphous substance poor in fibers and not particularly dense, therefore not very dyeable with normal histological stains. (businessplaners.com)

In the spirit of preventing and managing such occurrences, professional trainers, physiotherapists, sport physicians and physiologists are coming together at the CONNECT 2017 - CONNECTIVE TISSUES IN SPORTS MEDICINE conference. (uni-ulm.de)
Aug 16, 2017·Connective Tissue. (geertroovers.nl)
The aim of the ERN-RECONNET's annual work plan for 2017 is to establish a community to enhance transnational cooperation between different groups (healthcare providers, patients, caregivers and families, stakeholders, etc.) to develop a comprehensive and harmonized approach to rare and complex autoimmune and hereditary connective and musculoskeletal diseases (rCTDs). (europa.eu)

Besides surrounding blood vessels and nerves, one of the biggest jobs of loose connective tissue in the body is to attach the skin to the muscles. (pelvicpainrehab.com)

4] Thenceforth, nailfold capillaroscopy become an important diagnostic tool for diagnosing progressive connective tissue diseases such as systemic sclerosis, mixed connective tissue disease, lupus erythematosus, dermatomyositis, and polymyositis, and also in patients with Raynaud's phenomenon. (cdriadvlkn.org)

Myxomas are noncancerous growths of the body's connective tissue, including skin and muscle. (nih.gov)

Miller's Classes I and II recessions, in which the etiological factors are well diagnosed and eliminated, show great predictability of total coverage when the technique of subepithelial connective tissue graft is used. (bvsalud.org)
Case report and conclusion: The authors reported a clinical case in which a Miller's Class I recession was treated by the surgical technique of subepithelial connective tissue graft, obtaining total coverage, eliminating the aesthetic deficiency and the dentin hypersensitivity complained by patient. (bvsalud.org)
Treatment of Gingival Recession Defects with Pouch and Tunnel Technique Using Connective Tissue Graft and L. (medscimonit.com)
The versatile subepithelial connective tissue graft: a literature update. (bvsalud.org)
Among a multitude of surgical techniques and graft materials reported in literature , the subepithelial connective tissue graft (SCTG) has gained wide popularity and acceptance. (bvsalud.org)

7] In this article, authors have studied the precision of a dermoscope as a capillaroscopy in evaluating nailfold capillaries in various connective tissue diseases in the skin of color. (cdriadvlkn.org)

There can be difficulties relating to the muscles, skin, and joints as a result of connective tissue disease (CTD). (factdr.com)

Plus, research shows that connective tissue restrictions lead to local pain via the peripheral nervous system. (pelvicpainrehab.com)
Tissues are broadly classified in four types- epithelium connective tissue smooth muscle tissue nervous tissue In this article we are going to study about connective tissues. (gpatindia.com)

Pulmonary arterial hypertension (PAH) is a common and fatal complication of connective tissue diseases (CTDs). (stevefrithphotography.com)

What fibres are found in areolar tissue? (sarthaks.com)

Typically, connective tissues consist of a far higher proportion of non-living substance than living cells. (factdr.com)
Connective tissue consist of two basic elements, the extracellular matrix and the cells. (gpatindia.com)

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. (medlineplus.gov)
Skin rolling" or "connective tissue manipulation" as I'll be referring to it throughout this post, is a major component of our pelvic pain treatment technique here at PHRC. (pelvicpainrehab.com)
When the connective tissue that attaches the skin to the muscle becomes restricted (think thickened or dense) it can and does cause pain. (pelvicpainrehab.com)
When a PT carries out a pinch-roll test he or she will roll a fold of skin between his or her fingers, and note whether the tissue is thickened. (pelvicpainrehab.com)
However, the common term used to describe connective tissue manipulation is "skin rolling. (pelvicpainrehab.com)
After all, it's the connective tissue, not the skin that's being taken to task. (pelvicpainrehab.com)
It also helps in repair of tissues after injury and fixes skin to underlying muscles. (brainkart.com)
Authors evaluated the utility of dermoscopy in the study of nailfold capillaries in connective tissue diseases in patient with the skin of color. (cdriadvlkn.org)
The skin is connected by strands of fibrous tissues to deeper tissue layers, which separates the fat cell compartments. (queenbeeing.com)
Scleroderma is an autoimmune connective tissue and rheumatic disease that causes inflammation in the skin and other areas of the body. (nih.gov)
UVA is believed to damage connective tissue and increase the risk for developing skin cancer. (cdc.gov)
West Nile Virus transmission through tissue transplantation, for instance, skin, muscle, or connective tissues, has not been identified, and the risk for transmission by this route is not known. (cdc.gov)
Eight weeks after the donor's death, skin samples that had been treated in cryopreservative solution containing an antibiotic and unprocessed fat, muscle, tendon, and bone samples, all of which had been stored frozen at -70° Celsius at a tissue bank, were transferred to CDC. (cdc.gov)

D21.3 is a valid billable ICD-10 diagnosis code for Benign neoplasm of connective and other soft tissue of thorax . (icd10coded.com)
Harmony between hard and soft tissue morphologies is essential for form, function, and a good esthetic outlook. (bvsalud.org)
Replacement grafts for correction of soft tissue defects around the teeth have become important to periodontal plastic and implant surgical procedures . (bvsalud.org)
The Use of a Novel Porcine Derived Acellular Dermal Matrix (mucoderm®) in Peri-Implant Soft Tissue Augmentation: Preliminary Results of a Prospective Pilot Cohort Study. (straumann.com)
Hernia mesh products are designed to repair hernias and other defects by reinforcing the surrounding soft tissue. (meshbesher.com)

Mixed connective tissue disease--an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). (medscape.com)

The objective of the ERN ReCONNET's annual work plan for 2018 is to go on in the work already started during the first year, aimed at improving a community to enhance transnational cooperation between different groups to develop a comprehensive and harmonized approach to rare and complex autoimmune and hereditary connective and musculoskeletal diseases (rCTDs). (europa.eu)

The connective tissues are made up of cells of various shapes, not in direct contact with each other, but dispersed in an abundant extracellular matrix. (businessplaners.com)
Which connective tissue cell is responsible for the synthesis of the extracellular matrix? (businessplaners.com)
In both organ systems, these processes involve to a great extent the connective tissues, in particular the manner in which the extracellular materials are arranged to afford such movements. (stevefrithphotography.com)

i) Fluid or vascular tissue. (geertroovers.nl)
benign neoplasm of vascular tissue ( D18 . (icd10coded.com)
Corneas, heart valves, and vascular tissue were not procured. (cdc.gov)

More specifically, the inflammation associated with connective tissue will be explored. (uni-ulm.de)
Cerebrospinal Meningitis is an inflammation of the thin layer of connective tissue that covers the brain and the spinal cord. (who.int)

Introduction to Tissues Tissues Tissues are a group of cells that combine together to perform a particular function. (geertroovers.nl)
Tissue refers to a group of cells with intracellular components to perform a particular function. (geertroovers.nl)
The cells of the connective tissue are widely spaced and embedded in an intercellular matrix. (geertroovers.nl)
The components of the connective tissue are the intercellular substance known as the matrix, connective tissue cells and fibres. (brainkart.com)
A bio-ceramic additive reflects your body's own infrared rays, which help to break down cellulite cells and revitalize tissue. (queenbeeing.com)
Sometimes, and often for unknown reasons, the immune system turns on the healthy cells and tissues of the body, causing them to become inflamed and damaged. (factdr.com)
The most striking and characteristic histologic feature of the verruciform xanthoma is the presence of large foam cells in the connective-tissue papillae. (medscape.com)
Co-staining for proSPC and IL-1beta showed that while both exposures increased IL-beta+ cells in lung tissue, CNTinduced IL-1beta increases were largely specific to T2Ps. (cdc.gov)
Mast cells are immune cells found in connective tissues in your body. (hackyourgut.com)

Twenty-four 1-d-old broilers were distributed in 2 groups, pulmonary hypertensive broilers (PHB) and pulmonary nonhypertensive broilers (NPHB), to estimate possible differences between them in the expression of endothelin 1 (ET-1) and its type A receptor, connective tissue growth factor, platelet-derived growth factor, and adrenomedullin expression in the lungs. (eurekamag.com)
Connective tissue growth factor mRNA levels in the lungs of PHB were significantly higher than in the lungs of NPHB (P (eurekamag.com)
It has been demonstrated for the first time that ET-1, connective tissue growth factor, and adrenomedullin are upregulated in the lungs of PHB. (eurekamag.com)
This book concerns the microenvironment of the connective tissues in the walls of arteries and the stroma of lungs. (stevefrithphotography.com)

The EOMs exhibit a distinct 2-layer organization: an outer orbital layer, which acts only on connective tissue pulleys (see the section The Pulley System, later in the chapter), and an inner global layer, whose tendon inserts on the sclera to move the globe (Fig 3-4). (aao.org)

Yoshida S. Pulmonary arterial hypertension in connective tissue diseases. (medscape.com)
3 edition of Connective tissues in arterial and pulmonary disease found in the catalog. (stevefrithphotography.com)
Pulmonary arterial hypertension is the most common disease-related cause of death in patients with mixed connective tissue disease. (stevefrithphotography.com)
Pulmonary Manifestations of Connective Tissue Diseases toms, consistent PFTs and typical radiological find-ings. (stevefrithphotography.com)
By expert consensus, PAH is diagnosed when at right heart catheterisation a mean pulmonary Connective tissues in arterial and pulmonary disease book pressure (PAP) >25mmHg at rest or >30mmHg during exercise is measured, together with a normal wedge pressure and a normal or reduced cardiac output. (stevefrithphotography.com)

Most obvious among these connective functions, various social assets are built and/or maintained by government that form physical connections between the components of the society and enable people to physically interact with each other and come into possession of or experience goods and services they desire. (neweconomicperspectives.org)
On a fundamental level, all connective tissue is composed of more or less the same mix of components. (factdr.com)

IMSEAR at SEARO: Encephalopathy and severe neuropathy due to probable systemic vasculitis as an initial manifestation of mixed connective tissue disease. (who.int)
Matsui H, Udaka F, Oda M, Kubori T, Nishinaka K, Kameyama M. Encephalopathy and severe neuropathy due to probable systemic vasculitis as an initial manifestation of mixed connective tissue disease. (who.int)

Connective tissues hold the structures of the body together. (cedars-sinai.org)
When these connective tissues become inflamed, this can harm the proteins and surrounding areas of the body. (cedars-sinai.org)
When the body is subject to unaccustomed strains - as in a fall, for example - elastic, stable tissue will help prevent injury. (css.ch)
Connective Tissues These tissues help in connecting different parts of the body. (geertroovers.nl)
The most abundant tissue in animal body is the connective tissue. (geertroovers.nl)
It is a specialised connective tissue in the body. (aakash.ac.in)
The supporting or skeletal connective tissues forms the endoskeleton of the vertebrate body. (brainkart.com)
The blood and the lymph are the fluid connective tissues which link different parts of the body. (brainkart.com)
Connective tissue is the master connecting organ of your body - integrating movement, the brain, circulation, immune function, and emotional expression. (askdrlavine.com)
Craniosacral therapy is the gentlest form of body work that releases restriction of the connective tissues. (askdrlavine.com)
There are several types of tissue in the human body and each kind has a specified function. (factdr.com)
It is the most abundant form of tissue in the body and can take many different forms. (factdr.com)
Connective tissue is the material inside your body that supports many of its parts. (ezdoctor.com)
Treating the body this way can benefit massage clients who have plateaued with the use of massage treatments directed at non-fascial tissues. (seminarsforhealth.ca)

As of my last scans in December 2010, my lung lesion is only scarred tissue, the spine and lymph nodes are not visible, and the brain lesions are 60% reduced. (burzynskipatientgroup.org)

Inject intact proteins from peanuts, eggs and dairy (casein) products directly into the infantʼs muscle tissue 36 times before the age of 18 months. (yogaesoteric.net)
During aging, enzymes naturally present in the meat break down muscle proteins and connective tissues, while moisture evaporating from meat concentrates flavor. (outdoorlife.com)

Following clinical usage of the term 'connective tissue disorder' this grouping excludes some diseases affecting tissues classically considered to be connective tissue, such as bone. (ebi.ac.uk)
Patients who present with thin tissue, prominent teeth, aggressive tooth brushing habits, or thin bone may be subject to the exposure of root surfaces. (blackbeagledds.com)

The connective tissue (and therefore all its different types) derives from the mesenchyme. (businessplaners.com)
What are the 6 types of connective? (businessplaners.com)

It is a fibrous connective tissue densely packed with fibres and fibroblasts. (brainkart.com)

This layer of dense, fibrous connective tissue surrounds individual muscles and ligaments and groups them together for functional movement. (ashleyblackguru.com)
Where Is Dense Fibrous Connective Tissue Absent? (businessplaners.com)
Where is the irregular dense connective tissue found? (businessplaners.com)

Amigues JM, Cantagrel A, Abbal M, Mazieres B. Comparative study of 4 diagnosis criteria sets for mixed connective tissue disease in patients with anti-RNP antibodies. (medscape.com)
However, within specific populations such as at risk groups (e.g., patients with connective tissue disease), we urge increased awareness and adherence to consensus guidelines in terms of screening and diagnosis. (renalandurologynews.com)

Ground substance performs the role of a medium facilitating the exchange of substances between the blood and various tissues. (factdr.com)
Fibrillin is a substance that imparts strength to connective tissue. (factdr.com)
The fundamental substance, also called amorphous substance, is an acellular component of the connective tissue. (businessplaners.com)

Absorbable mesh is typically made of animal tissue that has been processed for medical use. (meshbesher.com)

This technique success has been mainly attributed to the double blood supply for graft's nutrition, originating from the connective tissue of both the periosteum and flap. (bvsalud.org)

Anatomy56

Organisms13

Diseases51

Chemicals and Drugs63

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Phenomena and Processes24

Disciplines and Occupations4

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture4

Information Science3

Destruction of hyaline cartilage in the sigmoid notch of the human ulna. (1/1596)

Structural changes in intramuscular connective tissue during the fattening of Japanese black cattle: effect of marbling on beef tenderization. (2/1596)

Relationship between development of intramuscular connective tissue and toughness of pork during growth of pigs. (3/1596)

Interaction of Borrelia burgdorferi with peripheral blood fibrocytes, antigen-presenting cells with the potential for connective tissue targeting. (4/1596)

Connective tissues: matrix composition and its relevance to physical therapy. (5/1596)

Recombinant human type II collagens with low and high levels of hydroxylysine and its glycosylated forms show marked differences in fibrillogenesis in vitro. (6/1596)

Altered connective tissue in children with congenital dislocation of the hip. (7/1596)

Insulin regulation of amino acid transport in mesenchymal cells from avian and mammalian tissues. (8/1596)

Connective Tissue

Connective Tissue Diseases

Connective Tissue Growth Factor

Connective Tissue Cells

Mixed Connective Tissue Disease

Immediate-Early Proteins

Intercellular Signaling Peptides and Proteins

Collagen

Scleroderma, Systemic

Fibroblasts

Neoplasms, Connective Tissue

Collagen Diseases

Tendons

Marfan Syndrome

Pseudoxanthoma Elasticum

Ehlers-Danlos Syndrome

Skin

Fibrosis

Nephroblastoma Overexpressed Protein

Extracellular Matrix

Gingival Recession

Ligaments

Subcutaneous Tissue

Elastic Tissue

Gingivoplasty

Gingiva

Transforming Growth Factor beta

Orbit

Extracellular Matrix Proteins

Growth Substances

Elastin

Raynaud Disease

Antibodies, Antinuclear

Cells, Cultured

Collagen Type I

Microscopy, Electron

Microscopy, Electron, Scanning

Lupus Erythematosus, Systemic

Meridians

Granulation Tissue

Transforming Growth Factor beta1

Collagen Type III

Cysteine-Rich Protein 61

Immunohistochemistry

Epithelial Attachment

Dermatomyositis

RNA, Messenger

Fibrillar Collagens

Autoantibodies

Lung Diseases, Interstitial

Oculomotor Muscles

Dermis

Cartilage

Wound Healing

Holothuria

Histocytochemistry

Fibronectins

Hydroxyproline

Proteoglycans

Sjogren's Syndrome

Microfibrils

Tongue

Pulmonary Fibrosis

CCN Intercellular Signaling Proteins

Mast Cells

Epithelium

Fascia

Glycosaminoglycans

Skin and Connective Tissue Diseases

Fluorescent Antibody Technique

Scleroderma, Localized

Decorin

Stichopus

Polymyositis

Arthritis, Rheumatoid

Microbial Collagenase

Sclera

Time Factors

Microfilament Proteins

Biomechanical Phenomena