Conjunctival diseases refer to a broad range of disorders that affect the conjunctiva, the mucous membrane covering the inner surface of the eyelids and the outer layer of the eyeball, causing symptoms such as redness, itching, irritation, discharge, and/or inflammation.
The prevention of infection or disease following exposure to a pathogen.

Epithelial hyperproliferation and transglutaminase 1 gene expression in Stevens-Johnson syndrome conjunctiva. (1/208)

In Stevens-Johnson syndrome, pathological keratinization of the ordinarily nonkeratinized corneal and conjunctival mucosal epithelia results in severe visual loss. We examined conjunctiva covering cornea in five eyes in the chronic cicatricial phase of Stevens-Johnson syndrome. Normal conjunctiva from five age-matched individuals was studied also. The number of epithelial cells in Stevens-Johnson syndrome conjunctiva that were immunoreactive with a monoclonal antibody, Ki-67, to a nuclear antigen found only in proliferating cells was greater than normal (93.8+/-19.8 cells above 100 basal cells versus 12.8+/-0.5 cells above 100 basal cells; P = 0.009). In addition, although clinical inflammation was mild, massive lymphocytic infiltration was seen in the substantia propria of conjunctiva covering cornea. In situ hybridization documented transglutaminase 1 (keratinocyte transglutaminase) mRNA in suprabasal cells of the abnormally thickened conjunctival epithelium in all Stevens-Johnson syndrome patients. In contrast, no message was detected in normal conjunctival or corneal epithelia. Transglutaminase 1 is expressed during the terminal differentiation of keratinocytes where it helps synthesize cornified cell envelopes. We speculate that in Stevens-Johnson syndrome, epithelial hyperproliferation, and transglutaminase 1 gene expression lead to the pathological keratinization of ocular surface mucosal epithelia.  (+info)

Ocular ochronosis in alkaptonuria patients carrying mutations in the homogentisate 1,2-dioxygenase gene. (2/208)

AIMS: To assess the involvement of the recently identified human homogentisate 1,2-dioxygenase gene (HGO) in alkaptonuria (AKU) in two unrelated patients with ochronosis of the conjunctiva, sclera, and cornea. METHODS: A mutation screen of the entire coding region of the HGO gene was performed using single stranded conformational analysis after polymerase chain reaction with oligonucleotide primers flanking all 14 exons of the HGO gene. Fragments showing aberrant mobility were directly sequenced. RESULTS: Two homozygous missense mutations, L25P and M368V, were identified, each of which leads to the replacement of a highly conserved amino acid in the HGO protein. CONCLUSIONS: The authors describe a novel mutation, L25P, in the German population and bring to 18 the total number of known HGO mutations.  (+info)

Combined effect of Interceed and 5-fluorouracil on delayed adjustable strabismus surgery. (3/208)

AIMS/BACKGROUND: To discover a more reliable method of performing delayed suture adjustment as a basis to investigate whether delayed adjustment actually provides more stable results. In order to prevent the formation of postoperative adhesions and delay the time of adjustment, an animal study was performed to determine the combined effect of physical barriers, Viscoat and Interceed, and a pharmacological agent, 5-fluorouracil (5-FU). METHODS: 38 rabbit eyes were divided into three groups. After recession of the superior rectus muscle (SRM), 5-FU was applied beneath and over the SRM in group 5-FU. Group I-f had Interceed and 5-FU and group I-fv, Interceed, 5-FU, and Viscoat. Delayed adjustment was performed once on each SRM at 1, 2, and 3 weeks postoperatively. The possible length and the necessary force to adjust as well as the degree of adhesions were recorded. RESULTS: 5-FU delayed the adjustment for up to 1 week after surgery in three out of four eyes. Combined use of Interceed and 5-FU could delay the adjustment for up to 1 week after surgery in three out of five eyes. Addition of Viscoat could delay the adjustment for up to 1 week after surgery in four out of five eyes. Adjustment was possible on only one of four eyes thereafter. CONCLUSIONS: Combined use of Interceed, 5-FU, and Viscoat could delay the adjustment in rabbits until 1 week postoperatively.  (+info)

Transforming growth factor-beta1, -beta2, and -beta3 in vivo: effects on normal and mitomycin C-modulated conjunctival scarring. (4/208)

PURPOSE: To compare the effects of the three human isoforms of transforming growth factor (TGF)-beta in vivo using a mouse model of conjunctival scarring, both in normal eyes and after treatment with MMC, with a view to delineating the role of this growth factor in glaucoma filtration surgery. METHODS: Application of recombinant human TGF-beta was assessed in a prospective, randomized study of mouse conjunctival scarring, in which subconjunctival TGF-beta1, -beta2, and -beta3 (all 10(-9) M) were compared with control (phosphate-buffered saline [PBS] carrier) and mitomycin C (MMC; 0.4 mg/ml) treatment at 6 hours, and 1, 3, and 7 days after surgery (six eyes/treatment/time point). Effects of TGF-beta2 on eyes previously treated with MMC were also assessed. Histologic studies of enucleated eyes were performed to analyze development of the scarring response, extracellular matrix deposition, and the inflammatory cell profile. RESULTS: All three isoforms of TGF-beta behaved in a similar manner in vivo, being associated with a rapid-onset and exaggerated scarring response compared with control and MMC treatment. TGF-beta-treated eyes showed evidence of an earlier peak in inflammatory cell activity (P < 0.05) and increased collagen type III deposition (P < 0.05). TGF-beta2 treatment significantly stimulated scarring after MMC application (P < 0.05). CONCLUSIONS: TGF-beta1, -beta2, and -beta3 appear to have similar actions in vivo and stimulate the conjunctival scarring response. Application of TGF-beta2 modified the effects of MMC. All TGF-beta isoforms may be potent modulators of the conjunctival scarring response. These studies indicate that TGF-beta2 may naturally modify the antiscarring effects of antimetabolites such as MMC in glaucoma filtration surgery.  (+info)

Human anti-transforming growth factor-beta2 antibody: a new glaucoma anti-scarring agent. (5/208)

PURPOSE: Currently available anti-scarring regimens for glaucoma filtration surgery have potentially blinding complications and thus the need for alternative and safer agents. The effects of a new antibody to transforming growth factor (TGF)-beta2 on in vitro and in vivo conjunctival scarring and after glaucoma filtration surgery were investigated. METHODS: The activity of a novel recombinant monoclonal neutralizing antibody (mAb) to human TGF-2 (rhAnti-TGF-beta2 mAb) was studied in conjunctival fibroblast-mediated proliferation, migration, and collagen contraction. Its safety in subconjunctival administration was assessed in vivo, and, in a rabbit model of glaucoma filtration surgery, its effects on conjunctival scarring and filtration surgery outcome were investigated. RESULTS: The rhAnti-TGF-beta2 mAb effectively inhibited TGF-beta2-mediated conjunctival scarring activity in vitro, at 50% inhibitory concentrations (IC50) of less than 1 nM. It significantly improved glaucoma filtration surgery outcome in an animal model of aggressive conjunctival scarring compared with control (P = 0.0291) and was clinically safe, nontoxic, and well tolerated after subconjunctival administration. CONCLUSIONS: Subconjunctival rhAnti-TGF-beta2 mAb treatment significantly affects surgical outcome and effectively reduces conjunctival scarring both in vitro and in vivo. It appears safe for subconjunctival administration and when compared with mitomycin-C treatment histologically, much less destructive to local tissue. rhAnti-TGF-beta2 mAb may have potential as a new anti-scarring agent for use in glaucoma filtration surgery.  (+info)

Tear fluid gelatinase B activity correlates with IL-1alpha concentration and fluorescein clearance in ocular rosacea. (6/208)

PURPOSE: To correlate tear fluorescein clearance with interleukin-1alpha (IL-1alpha) concentration and gelatinase B (matrix metalloproteinase [MMP]-9) activity in the tear fluid of patients with ocular rosacea and normal control subjects. METHODS: Gelatinase activity was evaluated by gelatin zymography in tear fluid obtained from 13 patients with ocular rosacea (including 1 patient with recurrent epithelial erosion, 2 with recurrent peripheral corneal infiltrates and vascularization, and 2 patients with epithelial basement membrane dystrophy) and 13 normal subjects with normal aqueous tear production and no irritation symptoms. Tear fluorescein clearance was evaluated by measuring fluorescence in tear fluid collected from the inferior meniscus 15 minutes after instillation of 5 microl of 2% Na-fluorescein with a CytoFluor II fluorometer. Pro-MMP-9 and IL-1alpha concentrations in the tear fluid were measured by enzyme-linked immunosorbent assay (ELISA). RESULTS: Compared with normal control subjects, patients with ocular rosacea had a greater delay of tear fluorescein clearance (P < 0.001), a higher tear IL-1alpha concentration (P < 0.001), and a greater pro-gelatinase B (92 kDa) activity (P < 0.001) in their tear fluid. The 84-kDa active form of gelatinase B was observed in 46% of the rosacea tear samples and none of the controls. The zymographic results were confirmed by ELISA that showed a significantly greater concentration of pro-MMP-9 (92 kDa) in the tear fluid of rosacea patients than controls. Delayed tear clearance was correlated with elevated tear IL-1alpha concentration (p=0.67, P < 0.001) and increased tear gelatinase B activity (p=0.84, P < 0.001). Tear IL-1alpha concentration was correlated with tear gelatinase B activity (p=0.58, P < 0.002). CONCLUSIONS: Gelatinase B (MMP-9) activity is greater in patients with ocular rosacea than in normal eyes. The majority of this activity is due to 92-kDa proform of this enzyme. This activity is correlated with delayed tear clearance and tear fluid concentration of interleukin-1alpha, a proinflammatory cytokine that has been reported to stimulate gelatinase B production. Elevated gelatinase B activity in ocular rosacea may be involved in the pathogenesis of the irritation symptoms, recurrent epithelial erosions, vascularization, and epithelial basement membrane dystrophy that develops in the corneas of patients with this condition.  (+info)

Overexpression of MMP-1 and MMP-3 by cultured conjunctivochalasis fibroblasts. (7/208)

PURPOSE: To determine whether conjunctivochalasis, denoting redundant, loose, nonedematous inferior bulbar conjunctiva, is associated with increased expression and activity of matrix metalloproteinases (MMPS) over their tissue inhibitors (TIMPs). METHODS: Expression of transcripts and proteins of MMPs, TIMPs, and urokinase plasminogen activator (uPA) by cultured normal human conjunctival and conjunctivochalasis fibroblasts was determined by Northern hybridization, enzyme-linked immunosorbent assay (ELISA), and Western blot analysis, respectively. Gelatin and casein zymography and quantitative collagenase activity assay were performed in the serum-free conditioned media. RESULTS: Compared with normal conjunctival fibroblasts from six subjects, conjunctivochalasis fibroblasts from eight patients showed markedly increased transcript expression of MMP-1 (5- to 32-fold) and MMP-3 (4 to 30-fold), whereas that of MMP-2, TIMP-1, TIMP-2, and uPA was similar between the two groups. Protein levels were increased in the serum-free conditioned media of conjunctivochalasis fibroblasts for MMP-1 (3.5- to 7.6-fold) and MMP-3 (2.3- to 13-fold), determined by ELISA and Western blot analysis. There was increased caseinolytic activity of MMP-3 and collagenolytic activity of MMP-1 (2.2-fold) by conjunctivochalasis fibroblasts, whereas no difference was noted between these two types of fibroblasts in the protein and gelatinolytic activity of MMP-2 or expression of TIMP-1 and TIMP-2 proteins, although that of TIMP-1 transcript was slightly higher in some conjunctivochalasis fibroblasts. No expression of MMP-9 was detected. CONCLUSIONS: Overexpression of MMP-1 and MMP-3 mRNA by conjunctivochalasis fibroblasts is correlated with their increased protein levels and proteolytic activities. Collectively, these data help explain how conjunctivochalasis manifests excessive degradation of the conjunctival matrix and Tenon's capsule.  (+info)

Key factors in the subjective and objective assessment of conjunctival erythema. (8/208)

PURPOSE: To establish objectively measurable characteristics of the conjunctival vasculature that correspond with the judgment of erythema by human observers. METHODS: Color images of bulbar conjunctiva from 21 subjects were digitally analyzed to extract the following variables characteristic of the scene: vessel width (W), number of vessels (V), proportion of area occupied by vessels (PA), relative redness both in vessels (RRV) and in the whole image (RRI), red-green difference both in vessels (RGV) and in the whole image (RGI), red-blue difference both in vessels (RBV) and in the whole image (RBI), and red hue value (RHV). These data were compared with subjective judgments by a panel of seven trained observers who independently rated erythema in the same images, using a 0 to 4 scale with decimal interpolation between grades. RESULTS: Correlation analysis indicated significant associations (P<0.05) between the mean response of the human observers and all the objective variables except RHV. Associations with the morphometric variables PA (R2 = 0.93) and V(R2 = 0.90) were markedly stronger than for the best colorimetric variable RBV (R2 = 0.62). CONCLUSIONS: Judgments of erythema made by human observers do not rely primarily on color but can be closely approximated by a univariate, linear model involving only the proportion of the scene occupied by vessels. Under the conditions of this study, grading of erythema by trained observers can be considered to constitute measurement to at least an interval level.  (+info)

Conjunctival diseases refer to a group of medical conditions that affect the conjunctiva, which is the thin, clear mucous membrane that covers the inner surface of the eyelids and the white part of the eye (known as the sclera). The conjunctiva helps to keep the eye moist and protected from irritants.

Conjunctival diseases can cause a range of symptoms, including redness, itching, burning, discharge, grittiness, and pain. Some common conjunctival diseases include:

1. Conjunctivitis (pink eye): This is an inflammation or infection of the conjunctiva that can be caused by viruses, bacteria, or allergies. Symptoms may include redness, itching, discharge, and watery eyes.
2. Pinguecula: This is a yellowish, raised bump that forms on the conjunctiva, usually near the corner of the eye. It is caused by an overgrowth of connective tissue and may be related to sun exposure or dry eye.
3. Pterygium: This is a fleshy growth that extends from the conjunctiva onto the cornea (the clear front part of the eye). It can cause redness, irritation, and vision problems if it grows large enough to cover the pupil.
4. Allergic conjunctivitis: This is an inflammation of the conjunctiva caused by an allergic reaction to substances such as pollen, dust mites, or pet dander. Symptoms may include redness, itching, watery eyes, and swelling.
5. Chemical conjunctivitis: This is an irritation or inflammation of the conjunctiva caused by exposure to chemicals such as chlorine, smoke, or fumes. Symptoms may include redness, burning, and tearing.
6. Giant papillary conjunctivitis (GPC): This is a type of allergic reaction that occurs in response to the presence of a foreign body in the eye, such as a contact lens. Symptoms may include itching, mucus discharge, and a gritty feeling in the eye.

Treatment for conjunctival diseases depends on the underlying cause. In some cases, over-the-counter medications or home remedies may be sufficient to relieve symptoms. However, more severe cases may require prescription medication or medical intervention. It is important to consult with a healthcare provider if you experience persistent or worsening symptoms of conjunctival disease.

Post-exposure prophylaxis (PEP) is the medical practice of using antiviral medications to prevent the development of a disease after an exposure to that disease. It is most commonly used in the context of preventing HIV infection, where it involves taking a combination of antiretroviral drugs for 28 days following potential exposure to the virus, such as through sexual assault or accidental needlestick injuries.

The goal of PEP is to reduce the risk of HIV infection by stopping the virus from replicating and establishing itself in the body. However, it is not 100% effective and should be used in conjunction with other preventative measures such as safe sex practices and proper use of personal protective equipment.

It's important to note that PEP must be started as soon as possible after exposure, ideally within 72 hours, but preferably within 24 hours, for it to be most effective. The decision to initiate PEP should be made in consultation with a medical professional and will depend on various factors such as the type of exposure, the risk of transmission, and the individual's medical history.

It results either from disease (conjunctival sequelae of trachoma) or trauma. Cicatricial pemphigoid and, in severe cases, ... Ankyloblepharon Holsclaw, DS (1998). "Ocular cicatricial pemphigoid and its treatment is surgery by conjunctival rotate graft ...
... also known as Weil's disease) develop conjunctival suffusion. When it does occur, it develops towards the end of the early ... Conjunctival suffusion may also occur in patients with a Hantavirus infection. In a 1994 study of 17 patients with Hantavirus ... Conjunctival suffusion is characterized by redness of the conjunctiva that resembles conjunctivitis, but it does not involve ... Conjunctival suffusion is an eye finding occurring early in leptospirosis, which is caused by Leptospira interrogans. ...
... tacrolimus eye drops in eyes with severe allergic conjunctival diseases". Allergy, Asthma, and Clinical Immunology. 17 (1): 11 ... Contraindications and precautions include: Hepatic disease Immunosuppression Infants Infection Neoplastic disease, such as: ... exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and ... The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. ...
Conjunctival incisional biopsy is occasionally done when granulomatous diseases (e.g., sarcoidosis) or dysplasia are suspected ... 2015). Epidemiology and Prevention of Vaccine-Preventable Diseases. U.S. Dept. of Health & Human Services, Centers for Disease ... Conjunctivitis is the most common eye disease. Rates of disease is related to the underlying cause which varies by the age as ... The rapid spread of the disease led to the temporary closure of schools in the region. This event marked one of the largest ...
"Conjunctival flaps in the treatment of corneal disease with reference to a new technique of application". AMA Arch Ophthalmol. ... Cornea & External Disease Archived 2014-03-27 at the Wayback Machine, at the New York Eye and Ear Infirmary; by Mark Speaker ... A Gundersen flap, also known as Gundersen's flap, Gundersen's conjunctival flap, or conjunctivoplasty, and often misspelled ... Gunderson, is a surgical procedure for correcting corneal disease. It involves excising a damaged section of cornea, and ...
Runny eyes and other conjunctival problems can be caused by dental disease or a blockage of the tear duct. Environmental ... Rabbit hemorrhagic disease (RHD), also known as viral hemorrhagic disease (VHD) or rabbit calicivirus disease (RCD), is caused ... "Rabbit Hemorrhagic Disease: Viral Hemorrhagic Disease of Rabbits, Rabbit Calicivirus Disease" (PDF). CFSPH.IAState.edu. Iowa ... as it may hide signs of disease and is not considered a practical response for such a rapidly spreading disease. In the UK, ...
... and conjunctival cicatricial disease, with visual loss. Kohl was used not only as a cosmetic but also as a medicinal collyrium ... There are a number of endemic ocular diseases in the Nile region including trachoma - which is caused by a chlamydial bacterium ... use of kohl across the Mediterranean and the Middle East attests to its ability to protect the eye from infectious disease and ...
... further study over longer follow-up periods with somewhat better results occurring in patients with conjunctival disease; and 5 ... Disease that moves past a localized stage to become disseminated, rapidly progressive disease, and symptomatic disease have ... where the bacterium has not been associated with the disease. Treatment of Borrelia burdorferi-negative disease or disease for ... Patients with extensive disease or disease that has progressed to a higher grade lymphoma (principally diffuse B-cell lymphoma ...
... are chronic allergic diseases wherein eosinophils, conjunctival fibroblasts, epithelial cells, mast cells, and TH2 lymphocytes ... VKC is a disease of childhood and is prevalent in males living in warm climates. AKC is frequently observed in males between ... Allergic conjunctivitis is common in people who have other signs of allergic disease such as hay fever, asthma and eczema.[ ... Symptoms of the aforementioned ocular diseases include itching and pink to reddish eye(s). These two eye conditions are ...
Risk factors for the disease are exposure to sun (specifically occupational), exposure to UVB, and light-colored skin. Other ... Conjunctival squamous cell carcinoma (conjunctival SCC) and corneal intraepithelial neoplasia comprise ocular surface squamous ... Treatment of conjunctival SCC is usually surgical excision followed by cryotherapy. After this procedure, Conjunctival SCC can ... Mortality for conjunctival SCC ranges from 0-8%. Diagnosis is often made by biopsy, as well as CT (in the case of invasive SCC ...
Bilateral conjunctival inflammation has been reported to be the most common symptom after fever. It typically involves the ... Children with Kawasaki disease should be hospitalized and cared for by a physician who has experience with this disease. In an ... The disease is the leading cause of acquired heart disease in children in developed countries, which include the formation of ... Kawasaki disease is predominantly a disease of young children, with 80% of patients younger than five years of age. About 2,000 ...
Other ocular findings can include conjunctival and retinal vascular abnormalities and anterior/posterior spoke-like cataract. ... Fabry disease, also known as Anderson-Fabry disease, is a rare genetic disease that can affect many parts of the body, ... Fabry disease is one of a group of conditions known as lysosomal storage diseases. The genetic mutation that causes Fabry ... Many disease-causing mutations have been noted. Kidney biopsy may also be suggestive of Fabry disease if excessive lipid ...
Symptoms include prostration, dyspnea, edema, conjunctival injection, viral exanthema, and CNS symptoms, including encephalitis ... Center for Disease Control, Marburg Haemorrhagic Fever. Center for Disease Control, Known Cases and Outbreaks of Marburg ... MVD is clinically indistinguishable from Ebola virus disease (EVD), and it can also easily be confused with many other diseases ... Martini, G. A. (1971). "Marburg Virus Disease. Clinical Syndrome". In Martini, G. A.; Siegert, R. (eds.). Marburg Virus Disease ...
Conjunctival limbal autograft (CLAU) involves transplantation of limbal tissue from a patient's healthy eye. As the procedure ... However, further surgical intervention may be needed if these approaches are unsuccessful, or when disease is more severe. ... Types of surgeries: In the case of a partial LSCD:, a sequential sector conjunctival epitheliectomy (SSCE) can be performed to ... Additionally, these cells also prevent the conjunctival epithelial cells from migrating onto the surface of the cornea. Damage ...
... as well as through inhalation and conjunctival exposure. The rate that the virus can spread is highly influenced by its ... Pacheco's disease is a highly infectious and acute bird disease caused by a species of herpesvirus, Psittacid alphaherpesvirus ... If a bird survives Pacheco's disease, it may later develop internal papilloma disease in its gastrointestinal tract. Pacheco's ... "Hygiene Protocols for the Prevention and Control of Diseases (Particularly Beak and Feather Disease) in Australian Birds" (PDF ...
Conjunctival concretion - development of hard deposits under the eyelid (H15.0) Scleritis - a painful inflammation of the ... International Statistical Classification of Diseases (WHO ICD-10) - Diseases of the eye and adnexa (ICD-10 codes H00-H59) ... This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known ... World Health Organization ICD-10 codes: Diseases of the eye and adnexa (H00-H59). [1]. Retrieved 2010-07-28. International ...
... conjunctival injection, etc.) Class 3: Proptosis Class 4: Extraocular muscle involvement (usually with diplopia) Class 5: ... Less commonly, it has been known as Parry disease, Begbie disease, Flajan disease, Flajani-Basedow syndrome, and Marsh disease ... Graves' disease occurs in about 0.5% of people. Graves' disease data has shown that the lifetime risk for women is around 3% ... Since Graves' disease is an autoimmune disease that appears suddenly, often later in life, a viral or bacterial infection may ...
... including the conjunctival sign and iris atrophy are ocular manifestations that are strongly indicative of sickle cell disease ... Sickle cell disease is a systemic disease that affects several organs in the body. Management of the underlying disease can ... Numerous diseases that feature blood hyperviscosity similar to sickle cell disease can manifest as retinal venous tortuousity. ... Mutation at the 6th position of the beta chain is the cause of sickle cell disease. Due to sickle cell disease, vascular ...
March 2014). "Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity ... at KIR2DL2/KIR2DL3". PLOS Neglected Tropical Diseases. 8 (3): e2744. doi:10.1371/journal.pntd.0002744. PMC 3961204. PMID ...
Conjunctival biopsy may be advised if malignancy is suspected. Pingueculae may enlarge slowly over time, but it is a benign ... It may have an increased prevalence in Gaucher's disease. Diagnosis of pinguecula is usually done by an eye care professional ... A pinguecula is a common type of conjunctival stromal degeneration in the eye. It appears as an elevated yellow-white plaque in ... It is thought that the high reflectivity of the solid white scleral tissue underlying the conjunctival tissue may result in ...
He discovered this disease was caused by two bacteria. The first, and more serious strain was caused by a "gonococcus-like ... Weeks, J.E. "The bacillus of acute conjunctival catarrh, or 'pink eye'." Archive Ophthalmology 15 (1886): 441-51. Pittman, ... Sao Paulo is one of the most developed states in Brazil, which makes it easier to receive reports of outbreaks of diseases like ... Under the German Cholera Commission of Egypt, Koch studied 50 patients in Egypt who were suffering from Egyptian eye disease. ...
... conjunctivitis 372.4 Pterygium 372.5 Conjunctival degenerations and deposits 372.6 Conjunctival scars 372.7 Conjunctival ... 335 Anterior horn cell disease 335.0 Werdnig-Hoffmann disease 335.1 Spinal muscular atrophy 335.2 Motor neurone disease 335.8 ... Myelopathy in other diseases classified elsewhere 336.8 Other myelopathy 336.9 Unspecified diseases of spinal cord 337 ... Polyneuropathy in malignant disease (140-208†) 357.4* Polyneuropathy in other diseases classified elsewhere 357.5 Alcoholic ...
... and unspecified protein-calorie malnutrition 264 Vitamin A deficiency 264.0 With conjunctival xerosis 264.1 With conjunctival ... Disorders of carbohydrate transport and metabolism 271.0 Glycogenosis Von Gierke's disease McArdle's disease Pompe's disease ... 272.6 Lipodystrophy 272.7 Lipidoses Gaucher's disease Niemann-Pick disease Sea-blue histiocyte syndrome 272.8 Other disorders ... This is a shortened version of the third chapter of the ICD-9: Endocrine, Nutritional and Metabolic Diseases, and Immunity ...
James WD, Berger TG, Elston DM, Odom RB (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN ... 978-0-7216-2921-6. Shields C, Shields J (2008). Eyelid, conjunctival, and orbital tumors: atlas and textbook. Hagerstwon, MD: ... is a deposition of yellowish cholesterol-rich material that can appear anywhere in the body in various disease states. They are ... and within the same disease spectrum as eruptive xanthomata. Other types of xanthoma identified in the Medical Dictionary ...
In addition, conjunctival resection can be performed to temporarily remove local inflammatory mediators, followed by the use of ... PUK is associated with different ocular and systemic diseases. Mooren's ulcer is a common form of PUK. The majority of PUK is ... Wegner's granulomatosis: WG is a rare autoimmune disease associated with PUK. It causes vasculitis of the lower and upper ... Rheumatoid arthritis: Approximately 50% of PUK are related to collagen vascular diseases, in which RA is the most common ...
... may have potential use for the treatment of liver disease and liver cancer. Tetrandrine has potential therapeutic ... value to prevent excess scarring/fibrosis in conjunctiva following trabeculectomy or in patients with severe conjunctival ... "Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment". Science. 347 (6225): 995-998 ...
After an acute flare-up, no clinical signs of disease may be seen for a prolonged period, which can vary from a few hours to a ... Other ocular problems may also occur, including conjunctival and corneal oedema, and aqueous flare. ... If the disease is not properly treated, it will eventually lead to blindness. ERU occurs in horses worldwide, but is more ... Horses that suffer from this disease can never be considered cured, although they can be managed by careful use of the therapy ...
Farber's disease: Nodular corneal opacity may be seen in association with this rare autosomal recessive disease. Acquired ... Congenital corneal ulcers: Unilateral corneal opacity may occur in association with conjunctival injection and other signs of ... diseases of the eye (22 ed.). Elsevier India. pp. 195, 221. ISBN 978-81-312-3818-9. AK Khurana. "Diseases of the Cornea". ... It is a rare autosomal dominant disease caused by mutations in the DCN gene. In this bilateral Snowflake, whitish opacities ...
The disease was first discovered in North America and since then has been identified in almost every corner of the earth. The ... Other early symptoms may include nausea, vomiting, loss of appetite, and conjunctival injection (red eyes).[citation needed] ... Since R. rickettsii needs a moving vector to contract the disease to a viable host it is more likely that this pathogen has ... This disease is worst for elderly patients, males, African-Americans, alcoholics, and patients with G6PD deficiency. Deaths ...
Diseases caused by poxviruses have been known for much of recorded history. Smallpox in particular has been highly prominent in ... and conjunctival illnesses, but occasionally cause more severe illnesses, such as hemorrhagic cystitis, hepatitis, and ... The most notable disease-causing viruses in Varidnaviria are adenoviruses, poxviruses, and the African swine fever virus (ASFV ... Many animal viruses in the realm are associated with disease, including adenoviruses, poxviruses, and the African swine fever ...
West Nile Virus Infection and Conjunctival Exposure. Emerging Infectious Diseases. 2005;11(10):1648-1649. doi:10.3201/ ... Centers for Disease Control and Prevention. Laboratory-acquired West Nile virus infections-United States, 2002. MMWR Morb ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ...
Whereas Hodgkin lymphoma very rarely causes ocular disease, non-Hodgkin lymphoma (NHL) is the most common type of ocular ... MRI may miss the conjunctival disease. [37] Orbital lesions usually are hypointense [32] or isointense on T1-weighted MRI and ... The intracranial disease occurs in 56-85% of patients with ocular disease, and estimates suggest that 15-25% of patients who ... Advanced disease correlated with increased risk ratios of persistent disease at the final follow-up and lymphoma-related death. ...
Whereas Hodgkin lymphoma very rarely causes ocular disease, non-Hodgkin lymphoma (NHL) is the most common type of ocular ... MRI may miss the conjunctival disease. [37] Orbital lesions usually are hypointense [32] or isointense on T1-weighted MRI and ... The intracranial disease occurs in 56-85% of patients with ocular disease, and estimates suggest that 15-25% of patients who ... Advanced disease correlated with increased risk ratios of persistent disease at the final follow-up and lymphoma-related death. ...
It results either from disease (conjunctival sequelae of trachoma) or trauma. Cicatricial pemphigoid and, in severe cases, ... Ankyloblepharon Holsclaw, DS (1998). "Ocular cicatricial pemphigoid and its treatment is surgery by conjunctival rotate graft ...
Categories: Conjunctival Diseases Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ...
A specimen of conjunctival exudate also should be cultured for isolation of N. gonorrhoeae, since culture is needed for ... Severe Disease Intravenous (IV) therapy should be provided for patients with severe disease or complications necessitating ... 1993 Sexually Transmitted Diseases Treatment Guidelines SUGGESTED CITATION: Centers for Disease Control and Prevention. 1993 ... More than one of these diseases may be present among at least 3%-10% of patients with genital ulcers. Each disease has been ...
... of morphometric analysis of conjunctival blood vessel as an additional diagnostic indicator of health and vascular disease ... Is coronavirus a disease of the blood vessels?. bhf.org.uk , 4 days ago. , Article Details , Related Articles * Blood vessel ... Smorgasbord Health Column 2024 - This Years Focus - Cardiovascular Disease - The Circulatory System - Part One - How does ...
Local Renin-Angiotensin System Activation and Myofibroblast Formation in Graft Versus Host Disease-Associated Conjunctival ... TAGS: conjunctival epithelial cells, cornea, cytokine, glycocalyx, interleukin-6, mucins, tumor necrosis factors, proteins, ... TAGS: cornea, dry eye syndromes, graft-versus-host disease, mucins, rebamipide, mice, tissue transplants, tear film finding, ... TAGS: glucose, proteins, tight junctions, epithelial cells, cornea, conjunctival epithelial cells Invest. Ophthalmol. Vis. Sci ...
65 64 50 Manifestation of systemic disease, conjunctival 65 64 68 Manifestation of skin disease, conjunctival 65 65 00 Hematoma ... disease 76 27 00 Disease, Coats 76 28 00 Disease, Eales 76 28 00 Eales disease 76 30 00 Retinopathy, central serous NOS 76 ... 77 00 72 Disease, optic nerve, type not specified, associated with demyelinating disease 77 00 72 Disease, optic nerve, type ... secondary to other eye disease. /Code also precipitating disease/ 74 89 56 Opacity, lens, diabetic (snowflake) 74 99 00 Disease ...
Overt Disease. Significant Clinical Manifestations. fever (S), headache (S), prostration (S), conjunctival inflammation (S), ... Section XI - Human Disease. In Nature. Significant Residual. Reported Death. Significant Subclinical. Significant ... Human Disease. Geographic Distribution. References. Remarks. References. History. Abbreviations. Information Exchange User ... Centers for Disease Control and Prevention. 1600 Clifton Rd. Atlanta, GA 30333, USA. 800-CDC-INFO (800-232-4636). Contact CDC- ...
Kawasaki Disease - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical ... Usually within a day or two of fever onset, bilateral bulbar conjunctival injection appears without exudate. ... Kawasaki Disease (Kawasakis Disease). By Christopher P. Raab , MD, Sidney Kimmel Medical College at Thomas Jefferson ... Etiology of Kawasaki Disease The etiology of Kawasaki disease is unknown, but the epidemiology and clinical presentation ...
Corneal and conjunctival diseases Laser refractive surgery Cataract surgery Corneal transplantation Tissue Engineering Stem ...
Histoplasmosis is an infectious disease caused by inhaling the spores of a fungus called Histoplasma capsulatum. This disease ... conjunctival Newcastle infection, psittacosis, and dermatophytosis) are of concern to poultry workers. Non-zootic infectious ... Of thses diseases, histoplasmosis may be the one most likely to cause serious illness in a poultry worker. ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
Experimental Model - Conjunctival Contact-induced Diseases. None Experimental Model - Ingestion-induced Diseases. Gal d 2 (1) ... Experimental Model - Injection-induced Diseases. None Experimental Model - Skin-induced Diseases. Gal d 2 (1) Allergic Diseases ... Experimental Model - Inhalant-induced Diseases. Arm r HRP (1) Gal d 2 (11) ...
Experimental Model - Conjunctival Contact-induced Diseases. None Experimental Model - Ingestion-induced Diseases. None ... Experimental Model - Injection-induced Diseases. None Experimental Model - Skin-induced Diseases. None Allergic Diseases in ... Experimental Model - Inhalant-induced Diseases. Gal d 2 (1) ...
Experimental Model - Conjunctival Contact-induced Diseases. None Experimental Model - Ingestion-induced Diseases. Gal d 2 (2) ... Experimental Model - Skin-induced Diseases. Sta a SEA (1) Sta a SEB (1) Allergic Diseases in Animals. None Review, Editorial, ... Experimental Model - Inhalant-induced Diseases. Gal d 2 (28) Tri a Gliadin (1) Experimental Model - Injection-induced Diseases ...
Experimental Model - Conjunctival Contact-induced Diseases. None Experimental Model - Ingestion-induced Diseases. None ... Experimental Model - Injection-induced Diseases. None Experimental Model - Skin-induced Diseases. None Allergic Diseases in ... Experimental Model - Inhalant-induced Diseases. Hev b 3 (1) ...
Experimental Model - Conjunctival Contact-induced Diseases. None Experimental Model - Ingestion-induced Diseases. None ... Experimental Model - Injection-induced Diseases. None Experimental Model - Skin-induced Diseases. None Allergic Diseases in ...
Experimental Model - Conjunctival Contact-induced Diseases. None Experimental Model - Ingestion-induced Diseases. Bos d 5 (1) ... Experimental Model - Injection-induced Diseases. None Experimental Model - Skin-induced Diseases. Gal d 2 (2) Allergic Diseases ... Experimental Model - Inhalant-induced Diseases. Bos d 6 (1) Der p 1 (2) Gal d 2 (53) Meg c HC (1) Pen c 13 (1) Phl p 5 (1) ...
Experimental Model - Conjunctival Contact-induced Diseases. None Experimental Model - Ingestion-induced Diseases. Gal d 2 (1) ... Experimental Model - Skin-induced Diseases. Cry j 1 (1) Cry j 2 (1) Gal d 2 (2) Allergic Diseases in Animals. None Review, ... Experimental Model - Inhalant-induced Diseases. Bet v 1 (1) Fel d 1 (1) Gal d 2 (49) Gal d 4 (1) Phl p 1 (1) Phl p 5 (1) Sta a ...
Whereas Hodgkin lymphoma very rarely causes ocular disease, non-Hodgkin lymphoma (NHL) is the most common type of ocular ... MRI may miss conjunctival disease. [34] Orbital lesions are usually hypointense [29] or isointense on T1-weighted MRI and ... of patients with ocular disease, and estimates suggest that 15-25% of patients who present with CNS disease have ocular disease ... Advanced disease correlated with increased risk ratios of having persistent disease at the final follow-up and lymphoma-related ...
The conjunctival urate deposited in infectious diseases. Bulges seen by progesterone excursions or if the groin, although the ... Later, a cardiac disease caused by social problems.. Ovarian pain radiating down securely. Together, nexium without an rx ...
Conjunctival Goblet Cell Densities in Ocular Surface Disease. Arch Ophthalmol. 1984;102(7):1049-51. https://doi.org/10.1001/ ... G.I. Drozhzhyna, SI The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine доктор медичних наук, ... G.I. Drozhzhyna SI The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine ... L. M. Velychko SI The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine ...
Infants also can acquire conjunctival eye infections (gonococcal and chlamydial conjunctivitis) during birth when a mother has ... a sexually transmitted disease.. *. Other viral eye infections (viral keratitis). Besides common pink eye, other viral eye ...
... disease occurs when the immune system attacks the thyroid, causing it to become overactive. ... Puffy eyes (ophthalmopathy/thyroid eye disease), conjunctival irritation, lid retraction. *Enlarged and smooth thyroid gland ( ... disease and Hashimotos disease.. Treatment Graves disease is a lifelong condition that requires long-term medication to ... Graves disease is an autoimmune disorder which causes hyperthyroidism, the overproduction of thyroid hormones. The disease ...
Furthermore, some tortoises displayed physical abnormalities, including nasal discharge, wheezing, eyelid and conjunctival ... "The full effect of chronic disease on a long-lived species such as the gopher tortoise may take months to years to manifest in ... Floridas iconic gopher tortoises face serious threat from disease outbreak. The gopher tortoise may be in big trouble if ... "Long-term studies of these animals and other populations will help us to better understand the consequences of disease and ...
Corneal sequestration is an inherited disease of Persian, Himalayan and Burmese cats. Its cause is unknown. Different type of ... Application of bulbar conjunctival pedicle graft was resulted in elimination of discomfort and corneal vascularization in a ... Application of Bulbar Conjunctival Pedicle Graft in a Persian Cat with Corneal Sequestrum ... As a conclusion bulbar conjunctival pedicle graft following lamellar keratectomy can be used successfully in the treatment of ...
Conjunctival Diseases. *Contraceptives, Oral. *Cooperative Behavior. *Cornea. *Corneal Diseases. *Corneal Transplantation. * ...
BACKGROUND: Atopic keratoconjunctivitis (AKC) is a chronic allergic conjunctival disease. However, a mouse model of AKC to ... a novel biomarker for allergic conjunctival disease. METHODS: FADS mice, in which Ikk2 is deleted in dermal fibroblasts, were ... Conjunctival injection was significantly reduced in the LF group than in the placebo group (p = 0.0017, Mann-Whitney U-test). ... Tears and conjunctival fibroblasts were evaluated in order to assess allergic inflammation and the effect of specific drugs. ...
  • Corneal sequestration is an inherited disease of Persian, Himalayan and Burmese cats. (vin.com)
  • Application of bulbar conjunctival pedicle graft was resulted in elimination of discomfort and corneal vascularization in a month and there were no scar formation after 8 months. (vin.com)
  • As a conclusion bulbar conjunctival pedicle graft following lamellar keratectomy can be used successfully in the treatment of not fully effected stromal corneal necrosis in cats. (vin.com)
  • Whereas Hodgkin lymphoma rarely causes ocular disease, non-Hodgkin lymphoma (NHL) is the most common type of ocular lymphoma. (medscape.com)
  • The incidence of lymphoproliferative ocular diseases, especially malignant lymphoma, has increased over the years. (medscape.com)
  • Stevenson W, Chauhan SK, Dana R. Dry eye disease: an immune-mediated ocular surface disorder. (ozhurnal.com)
  • Conjunctival Goblet Cell Densities in Ocular Surface Disease. (ozhurnal.com)
  • OBJECTIVE: We sought to evaluate whether the ocular lesions that FADS mice spontaneously develop are similar to those of patients with AKC and to estimate the efficacy of topical treatments with tacrolimus and betamethasone for FADS mice by using tear periostin, a novel biomarker for allergic conjunctival disease. (bvsalud.org)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • SUGGESTED CITATION: Centers for Disease Control and Prevention. (cdc.gov)
  • Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)
  • Samples can be sent to the Centers for Disease Control and Prevention (CDC) for confirmatory testing (PCR and confirmatory serologic testing by the microscopic agglutination test). (cdc.gov)
  • Usually within a day or two of fever onset, bilateral bulbar conjunctival injection appears without exudate. (msdmanuals.com)
  • In this case bulbar conjunctival pedicle graft was used following lamellar keratectomy. (vin.com)
  • Different type of conjunctival graft is apply to remove the sequestrum. (vin.com)
  • In healthy people, adenovirus adeno-self-limiting disease can cause respiratory, gastrointestinal, or conjunctival inflammation. (ropecount.com)
  • Crohn disease is an idiopathic disorder that can involve the entire GI tract with transmural inflammation, noncaseating granulomas, and fissures. (medscape.com)
  • Acute and chronic inflammation, with lymphocytic and giant cell perivascular infiltrates, and lymphoid follicles are the most common histologic findings in oral and GI Crohn disease. (medscape.com)
  • Shtein RM, Sugar A. Pterygium and conjunctival degenerations. (medlineplus.gov)
  • [ 3 , 4 ] Lymphoproliferative disease of the orbit usually presents later in life and causes symptoms due to gradually increasing mass effect. (medscape.com)
  • This disease primarily affects a person's lungs, and its symptoms vary greatly. (cdc.gov)
  • Graves' disease has a wide range of symptoms and can present in varying degrees of severity in different patients. (medicalchannelasia.com)
  • 1 Clinical symptoms often present as a conjunctival hyperemia, tearing and itching. (reviewofoptometry.com)
  • Symptoms of Crohn disease include intermittent attacks of diarrhea, constipation, abdominal pain, and fever. (medscape.com)
  • Also, partial presentations (an absence of some of the following signs/symptoms) do not necessarily imply less severe disease. (cdc.gov)
  • Isabella Eckerle, head of the Center for Emerging Infectious Diseases at the University of Geneva, Switzerland, questioned that adenovirus was not detected in liver biopsies of children with acute hepatitis. (ropecount.com)
  • We describe a conjunctival exposure to WNV that occurred in the field and probably resulted in infection in the exposed person. (cdc.gov)
  • The etiology of Kawasaki disease is unknown, but the epidemiology and clinical presentation suggest an infection or, more likely, an abnormal immunologic response to an infection in genetically predisposed children. (msdmanuals.com)
  • Of approximately forty zoonotic diseases of agricultur al importance, six (Mycobacterium avium infection, erysipeloid, listerosis, conjunctival Newcastle infection, psittacosis, and dermatophytosis) are of concern to poultry workers. (cdc.gov)
  • 5 Increased hospitalization rates among patients with decompensated liver disease also predispose patients to nosocomial infections, including Clostridium difficile infection (CDI). (gastroenterologyandhepatology.net)
  • A recent study published in the journal Conservation Physiology by a team of wildlife biologists and conservationists found the tortoises are exposed to an outbreak of Mycoplasma agassizii , an infectious bacterium that causes upper respiratory tract diseases that are difficult to treat . (zmescience.com)
  • On the upside, if you can call it that way, none of the tortoises tested positive for Ranavirus or Herpesvirus, two other concerning microorganisms that are known to cause upper respiratory tract disease in gopher tortoises. (zmescience.com)
  • The study also revealed that adult tortoises were more likely than juveniles to have clinical signs of upper respiratory tract disease, and larger tortoises were more likely to have antibodies to Mycoplasma agassizii . (zmescience.com)
  • Respiratory tract infections aren't the only disease that gopher tortoises have to worry about. (zmescience.com)
  • purulent conjunctivitis, cervical lymphade- nopathy, skin rash, and oral mucosal and extremity changes characterize the disease. (who.int)
  • Infants also can acquire conjunctival eye infections (gonococcal and chlamydial conjunctivitis) during birth when a mother has a sexually transmitted disease. (allaboutvision.com)
  • The ratio of collagen fiber areas to conjunctival and scleral lesions was analyzed by Mallory-Azan staining. (molvis.org)
  • Densities of proliferative cell nuclear antigen-positive cells, chymase-positive cells, and areas of collagen fiber in conjunctival and scleral lesions were significantly decreased in MMC-treated eyes, compared with placebo-treated eyes (p=0.034, 0.034, 0.049, respectively). (molvis.org)
  • Whether patients with orofacial granulomatoses will subsequently develop intestinal manifestations of Crohn disease is uncertain, but histologic similarities between the oral lesions and the intestinal lesions are obvious. (medscape.com)
  • Tuberculosis (TB) is an infectious disease caused by the Mycobacterium tuberculosis complex. (annals.edu.sg)
  • Headache is very common in pituitary disease and is reported to be present in more than a third of all patients with pituitary adenomas. (medscape.com)
  • [ 1 ] Headaches are frequently linked to pituitary disease, and it is generally accepted that headache is a common presenting feature of pituitary adenomas and other sellar pathologies. (medscape.com)
  • However, any predisposition of a patient for primary headache will also contribute significantly to the development of headache in conjunction with pituitary disease. (medscape.com)
  • All articles reporting original data and review articles on headache and pituitary disease in peer reviewed journals were screened for inclusion into the present review. (medscape.com)
  • The diagnosis of Kawasaki disease is clini- cal and based on the presence of fever and East Mazandaran is located in the north of at least 4 of the above-mentioned clinical the Islamic Republic of Iran. (who.int)
  • Oral manifestations can prove crucial in diagnosis and usually parallel the intestinal disease course. (medscape.com)
  • [ 8 ] However, oral manifestations at follow-up once disease is controlled may not be a marker for recurring intestinal disease. (medscape.com)
  • Thyroid stimulating hormone receptor antibody ( TRAb ) is considered the gold standard in the diagnosis of Graves' disease. (medicalchannelasia.com)
  • Red Book: 2021-2024 Report of the Committee on Infectious Diseases , ed. 32, 2021. (msdmanuals.com)
  • Autoimmune disease is also a possibility. (msdmanuals.com)
  • Graves' disease is an autoimmune disorder which causes hyperthyroidism, the overproduction of thyroid hormones. (medicalchannelasia.com)
  • Her systemic disease history was positive for rheumatoid arthritis, for which she medicated with Enbrel (etanercept, Immunex) 50mg/week IM. (reviewofoptometry.com)
  • Histoplasmosis is an infectious disease caused by inhaling the spores of a fungus called Histoplasma capsulatum. (cdc.gov)
  • Humans acquire the disease through direct contact with urine from animals infected with leptospirosis or with urine-contaminated water or mud. (cdc.gov)
  • The disease usually affects young and middle-aged women who are genetically predisposed. (medicalchannelasia.com)
  • 2 Other factors known to increase the risk of infections after OLT include a pretransplant Model for End-Stage Liver Disease (MELD) score greater than 30, need for a second operation after OLT, posttransplant renal replacement therapy (RRT), and an intensive care unit (ICU) stay longer than 48 hours. (gastroenterologyandhepatology.net)
  • Is coronavirus a disease of the blood vessels? (serendeputy.com)
  • Objectives: To compare vaccinated-side axillary lymph node uptake on 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) after coronavirus disease-2019 (COVID-19) and influenza vaccination. (bvsalud.org)
  • We nistration of intravenous immunoglobulin undertook a retrospective review of the (IVIG) within the first 10 days of illness medical records of all cases with Kawasaki decreases the prevalence of coronary ar- disease referred, treated or discharged tery abnormalities (CAA) to 2%-5% [ 5-7 ]. (who.int)
  • Informa- host factors, including age, sex and race, tion concerning demographic, clinical and influence the occurrence of the disease [ 9 ]. (who.int)
  • The full effect of chronic disease on a long-lived species such as the gopher tortoise may take months to years to manifest in a population," said Annie Page-Karjian, lead author of the new study and a clinical veterinarian and an assistant research professor at FAU Harbor Branch. (zmescience.com)
  • When using these guidelines, consideration should be given to the disease prevalence and to other characteristics of the practice setting. (cdc.gov)
  • Whereas in pituitary apoplexy a mechanical component explains the almost universal association of the condition with headaches, this correlation is less clear in other forms of pituitary disease and a positive impact of surgery on headaches is not guaranteed. (medscape.com)
  • Kawasaki disease is a vasculitis, sometimes involving the coronary arteries, that tends to occur in infants and children between the ages of 1 year and 8 years. (msdmanuals.com)
  • Kawasaki disease is the leading cause of acquired heart disease in children. (msdmanuals.com)
  • Children of Japanese descent have a particularly high incidence, but Kawasaki disease occurs worldwide. (msdmanuals.com)
  • ABSTRACT We conducted a retrospective review of all cases of Kawasaki disease admitted to the major referral centres in Sari, East Mazandaran from 1 November 1997 to 30 October 2002. (who.int)
  • Fissures or fistulas may occur in persons with chronic disease. (medscape.com)
  • once the disease is diagnosed, echocardiography is done. (msdmanuals.com)
  • Rare Disease PHGKB is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other information that address the public health impact and translation of genomic and other precision health discoveries into improved health outcomes related to rare diseases. (cdc.gov)
  • Anti-thyroid peroxidase antibody ( anti-TPO ) is an autoantibody that suggests the cause of thyroid disease and is commonly found in patients with Graves' disease and Hashimoto's disease. (medicalchannelasia.com)
  • We believe this is the first reported case of apparent conjunctival transmission of WNV in an occupational setting. (cdc.gov)
  • These guidelines for the treatment of patients with sexually transmitted diseases (STDs) were developed by staff members of CDC after consultation with a group of invited experts who met in Atlanta on January 19-21, 1993. (cdc.gov)
  • Physicians and other health-care providers have a critical role in the effort to prevent and treat sexually transmitted diseases (STDs). (cdc.gov)
  • The classic presentation of markers indicative of Graves' disease include suppressed TSH and elevated T3 and T4 levels. (medicalchannelasia.com)
  • Of thses diseases, histoplasmosis may be the one most likely to cause serious illness in a poultry worker. (cdc.gov)
  • Negative serologic test results from samples collected in the first week of illness do not rule out disease. (cdc.gov)
  • The mouth is frequently involved in conditions that affect the skin or other multiorgan diseases. (medscape.com)
  • Patients with Graves' disease usually present with Graves' ophthalmopathy that causes swelling of the eyes to appear to bulge or protrude outward. (medicalchannelasia.com)
  • In patients that are untreated, Graves' disease can lead to heart rhythm disorders that can lead to heart failure. (medicalchannelasia.com)
  • Intraoral involvement in Crohn disease occurs in 8-29% of patients and may precede intestinal involvement. (medscape.com)
  • [ 9 ] Extraintestinal features are also common in persons with Crohn disease, and these may manifest systemically as arthritis, clubbing of the fingers, sacroiliitis, and erythema nodosum. (medscape.com)
  • If clinicians suspect leptospirosis in a patient, they should initiate treatment with antibiotics (e.g., doxycycline or penicillin) prior to receiving results of diagnostic tests, as earlier treatment is associated with a decrease in duration and severity of disease. (cdc.gov)
  • Proptosis and visible conjunctival mass are the common modes of presentation. (medscape.com)
  • This disease is most common in Western countries and is slightly more prevalent among white males. (medscape.com)
  • Graves' disease occurs when the immune system attacks the thyroid, causing it to become overactive. (medicalchannelasia.com)
  • This graph shows the total number of publications written about "Conjunctival Neoplasms" by people in this website by year, and whether "Conjunctival Neoplasms" was a major or minor topic of these publications. (wakehealth.edu)
  • Below are the most recent publications written about "Conjunctival Neoplasms" by people in Profiles. (wakehealth.edu)
  • The National Cancer Institute Surveillance, Epidemiology, and End Results program estimated that in 2008, 2,390 US men and women (1,340 men and 1,050 women) would be diagnosed with eye cancer and 240 people would die of this disease. (medscape.com)