The prevention of infection or disease following exposure to a pathogen.

Epithelial hyperproliferation and transglutaminase 1 gene expression in Stevens-Johnson syndrome conjunctiva. (1/208)

In Stevens-Johnson syndrome, pathological keratinization of the ordinarily nonkeratinized corneal and conjunctival mucosal epithelia results in severe visual loss. We examined conjunctiva covering cornea in five eyes in the chronic cicatricial phase of Stevens-Johnson syndrome. Normal conjunctiva from five age-matched individuals was studied also. The number of epithelial cells in Stevens-Johnson syndrome conjunctiva that were immunoreactive with a monoclonal antibody, Ki-67, to a nuclear antigen found only in proliferating cells was greater than normal (93.8+/-19.8 cells above 100 basal cells versus 12.8+/-0.5 cells above 100 basal cells; P = 0.009). In addition, although clinical inflammation was mild, massive lymphocytic infiltration was seen in the substantia propria of conjunctiva covering cornea. In situ hybridization documented transglutaminase 1 (keratinocyte transglutaminase) mRNA in suprabasal cells of the abnormally thickened conjunctival epithelium in all Stevens-Johnson syndrome patients. In contrast, no message was detected in normal conjunctival or corneal epithelia. Transglutaminase 1 is expressed during the terminal differentiation of keratinocytes where it helps synthesize cornified cell envelopes. We speculate that in Stevens-Johnson syndrome, epithelial hyperproliferation, and transglutaminase 1 gene expression lead to the pathological keratinization of ocular surface mucosal epithelia.  (+info)

Ocular ochronosis in alkaptonuria patients carrying mutations in the homogentisate 1,2-dioxygenase gene. (2/208)

AIMS: To assess the involvement of the recently identified human homogentisate 1,2-dioxygenase gene (HGO) in alkaptonuria (AKU) in two unrelated patients with ochronosis of the conjunctiva, sclera, and cornea. METHODS: A mutation screen of the entire coding region of the HGO gene was performed using single stranded conformational analysis after polymerase chain reaction with oligonucleotide primers flanking all 14 exons of the HGO gene. Fragments showing aberrant mobility were directly sequenced. RESULTS: Two homozygous missense mutations, L25P and M368V, were identified, each of which leads to the replacement of a highly conserved amino acid in the HGO protein. CONCLUSIONS: The authors describe a novel mutation, L25P, in the German population and bring to 18 the total number of known HGO mutations.  (+info)

Combined effect of Interceed and 5-fluorouracil on delayed adjustable strabismus surgery. (3/208)

AIMS/BACKGROUND: To discover a more reliable method of performing delayed suture adjustment as a basis to investigate whether delayed adjustment actually provides more stable results. In order to prevent the formation of postoperative adhesions and delay the time of adjustment, an animal study was performed to determine the combined effect of physical barriers, Viscoat and Interceed, and a pharmacological agent, 5-fluorouracil (5-FU). METHODS: 38 rabbit eyes were divided into three groups. After recession of the superior rectus muscle (SRM), 5-FU was applied beneath and over the SRM in group 5-FU. Group I-f had Interceed and 5-FU and group I-fv, Interceed, 5-FU, and Viscoat. Delayed adjustment was performed once on each SRM at 1, 2, and 3 weeks postoperatively. The possible length and the necessary force to adjust as well as the degree of adhesions were recorded. RESULTS: 5-FU delayed the adjustment for up to 1 week after surgery in three out of four eyes. Combined use of Interceed and 5-FU could delay the adjustment for up to 1 week after surgery in three out of five eyes. Addition of Viscoat could delay the adjustment for up to 1 week after surgery in four out of five eyes. Adjustment was possible on only one of four eyes thereafter. CONCLUSIONS: Combined use of Interceed, 5-FU, and Viscoat could delay the adjustment in rabbits until 1 week postoperatively.  (+info)

Transforming growth factor-beta1, -beta2, and -beta3 in vivo: effects on normal and mitomycin C-modulated conjunctival scarring. (4/208)

PURPOSE: To compare the effects of the three human isoforms of transforming growth factor (TGF)-beta in vivo using a mouse model of conjunctival scarring, both in normal eyes and after treatment with MMC, with a view to delineating the role of this growth factor in glaucoma filtration surgery. METHODS: Application of recombinant human TGF-beta was assessed in a prospective, randomized study of mouse conjunctival scarring, in which subconjunctival TGF-beta1, -beta2, and -beta3 (all 10(-9) M) were compared with control (phosphate-buffered saline [PBS] carrier) and mitomycin C (MMC; 0.4 mg/ml) treatment at 6 hours, and 1, 3, and 7 days after surgery (six eyes/treatment/time point). Effects of TGF-beta2 on eyes previously treated with MMC were also assessed. Histologic studies of enucleated eyes were performed to analyze development of the scarring response, extracellular matrix deposition, and the inflammatory cell profile. RESULTS: All three isoforms of TGF-beta behaved in a similar manner in vivo, being associated with a rapid-onset and exaggerated scarring response compared with control and MMC treatment. TGF-beta-treated eyes showed evidence of an earlier peak in inflammatory cell activity (P < 0.05) and increased collagen type III deposition (P < 0.05). TGF-beta2 treatment significantly stimulated scarring after MMC application (P < 0.05). CONCLUSIONS: TGF-beta1, -beta2, and -beta3 appear to have similar actions in vivo and stimulate the conjunctival scarring response. Application of TGF-beta2 modified the effects of MMC. All TGF-beta isoforms may be potent modulators of the conjunctival scarring response. These studies indicate that TGF-beta2 may naturally modify the antiscarring effects of antimetabolites such as MMC in glaucoma filtration surgery.  (+info)

Human anti-transforming growth factor-beta2 antibody: a new glaucoma anti-scarring agent. (5/208)

PURPOSE: Currently available anti-scarring regimens for glaucoma filtration surgery have potentially blinding complications and thus the need for alternative and safer agents. The effects of a new antibody to transforming growth factor (TGF)-beta2 on in vitro and in vivo conjunctival scarring and after glaucoma filtration surgery were investigated. METHODS: The activity of a novel recombinant monoclonal neutralizing antibody (mAb) to human TGF-2 (rhAnti-TGF-beta2 mAb) was studied in conjunctival fibroblast-mediated proliferation, migration, and collagen contraction. Its safety in subconjunctival administration was assessed in vivo, and, in a rabbit model of glaucoma filtration surgery, its effects on conjunctival scarring and filtration surgery outcome were investigated. RESULTS: The rhAnti-TGF-beta2 mAb effectively inhibited TGF-beta2-mediated conjunctival scarring activity in vitro, at 50% inhibitory concentrations (IC50) of less than 1 nM. It significantly improved glaucoma filtration surgery outcome in an animal model of aggressive conjunctival scarring compared with control (P = 0.0291) and was clinically safe, nontoxic, and well tolerated after subconjunctival administration. CONCLUSIONS: Subconjunctival rhAnti-TGF-beta2 mAb treatment significantly affects surgical outcome and effectively reduces conjunctival scarring both in vitro and in vivo. It appears safe for subconjunctival administration and when compared with mitomycin-C treatment histologically, much less destructive to local tissue. rhAnti-TGF-beta2 mAb may have potential as a new anti-scarring agent for use in glaucoma filtration surgery.  (+info)

Tear fluid gelatinase B activity correlates with IL-1alpha concentration and fluorescein clearance in ocular rosacea. (6/208)

PURPOSE: To correlate tear fluorescein clearance with interleukin-1alpha (IL-1alpha) concentration and gelatinase B (matrix metalloproteinase [MMP]-9) activity in the tear fluid of patients with ocular rosacea and normal control subjects. METHODS: Gelatinase activity was evaluated by gelatin zymography in tear fluid obtained from 13 patients with ocular rosacea (including 1 patient with recurrent epithelial erosion, 2 with recurrent peripheral corneal infiltrates and vascularization, and 2 patients with epithelial basement membrane dystrophy) and 13 normal subjects with normal aqueous tear production and no irritation symptoms. Tear fluorescein clearance was evaluated by measuring fluorescence in tear fluid collected from the inferior meniscus 15 minutes after instillation of 5 microl of 2% Na-fluorescein with a CytoFluor II fluorometer. Pro-MMP-9 and IL-1alpha concentrations in the tear fluid were measured by enzyme-linked immunosorbent assay (ELISA). RESULTS: Compared with normal control subjects, patients with ocular rosacea had a greater delay of tear fluorescein clearance (P < 0.001), a higher tear IL-1alpha concentration (P < 0.001), and a greater pro-gelatinase B (92 kDa) activity (P < 0.001) in their tear fluid. The 84-kDa active form of gelatinase B was observed in 46% of the rosacea tear samples and none of the controls. The zymographic results were confirmed by ELISA that showed a significantly greater concentration of pro-MMP-9 (92 kDa) in the tear fluid of rosacea patients than controls. Delayed tear clearance was correlated with elevated tear IL-1alpha concentration (p=0.67, P < 0.001) and increased tear gelatinase B activity (p=0.84, P < 0.001). Tear IL-1alpha concentration was correlated with tear gelatinase B activity (p=0.58, P < 0.002). CONCLUSIONS: Gelatinase B (MMP-9) activity is greater in patients with ocular rosacea than in normal eyes. The majority of this activity is due to 92-kDa proform of this enzyme. This activity is correlated with delayed tear clearance and tear fluid concentration of interleukin-1alpha, a proinflammatory cytokine that has been reported to stimulate gelatinase B production. Elevated gelatinase B activity in ocular rosacea may be involved in the pathogenesis of the irritation symptoms, recurrent epithelial erosions, vascularization, and epithelial basement membrane dystrophy that develops in the corneas of patients with this condition.  (+info)

Overexpression of MMP-1 and MMP-3 by cultured conjunctivochalasis fibroblasts. (7/208)

PURPOSE: To determine whether conjunctivochalasis, denoting redundant, loose, nonedematous inferior bulbar conjunctiva, is associated with increased expression and activity of matrix metalloproteinases (MMPS) over their tissue inhibitors (TIMPs). METHODS: Expression of transcripts and proteins of MMPs, TIMPs, and urokinase plasminogen activator (uPA) by cultured normal human conjunctival and conjunctivochalasis fibroblasts was determined by Northern hybridization, enzyme-linked immunosorbent assay (ELISA), and Western blot analysis, respectively. Gelatin and casein zymography and quantitative collagenase activity assay were performed in the serum-free conditioned media. RESULTS: Compared with normal conjunctival fibroblasts from six subjects, conjunctivochalasis fibroblasts from eight patients showed markedly increased transcript expression of MMP-1 (5- to 32-fold) and MMP-3 (4 to 30-fold), whereas that of MMP-2, TIMP-1, TIMP-2, and uPA was similar between the two groups. Protein levels were increased in the serum-free conditioned media of conjunctivochalasis fibroblasts for MMP-1 (3.5- to 7.6-fold) and MMP-3 (2.3- to 13-fold), determined by ELISA and Western blot analysis. There was increased caseinolytic activity of MMP-3 and collagenolytic activity of MMP-1 (2.2-fold) by conjunctivochalasis fibroblasts, whereas no difference was noted between these two types of fibroblasts in the protein and gelatinolytic activity of MMP-2 or expression of TIMP-1 and TIMP-2 proteins, although that of TIMP-1 transcript was slightly higher in some conjunctivochalasis fibroblasts. No expression of MMP-9 was detected. CONCLUSIONS: Overexpression of MMP-1 and MMP-3 mRNA by conjunctivochalasis fibroblasts is correlated with their increased protein levels and proteolytic activities. Collectively, these data help explain how conjunctivochalasis manifests excessive degradation of the conjunctival matrix and Tenon's capsule.  (+info)

Key factors in the subjective and objective assessment of conjunctival erythema. (8/208)

PURPOSE: To establish objectively measurable characteristics of the conjunctival vasculature that correspond with the judgment of erythema by human observers. METHODS: Color images of bulbar conjunctiva from 21 subjects were digitally analyzed to extract the following variables characteristic of the scene: vessel width (W), number of vessels (V), proportion of area occupied by vessels (PA), relative redness both in vessels (RRV) and in the whole image (RRI), red-green difference both in vessels (RGV) and in the whole image (RGI), red-blue difference both in vessels (RBV) and in the whole image (RBI), and red hue value (RHV). These data were compared with subjective judgments by a panel of seven trained observers who independently rated erythema in the same images, using a 0 to 4 scale with decimal interpolation between grades. RESULTS: Correlation analysis indicated significant associations (P<0.05) between the mean response of the human observers and all the objective variables except RHV. Associations with the morphometric variables PA (R2 = 0.93) and V(R2 = 0.90) were markedly stronger than for the best colorimetric variable RBV (R2 = 0.62). CONCLUSIONS: Judgments of erythema made by human observers do not rely primarily on color but can be closely approximated by a univariate, linear model involving only the proportion of the scene occupied by vessels. Under the conditions of this study, grading of erythema by trained observers can be considered to constitute measurement to at least an interval level.  (+info)

All 18 patients treated for conjunctivochalasis had watery eyes. Of the 18 patients, nine (50.0%) had plerolacrima14 (tears filling the eyes but not running down the face), while seven (38.9%) had epiphora (tears running down the face), and two patients (11.1%) had both symptoms. In combination with conjunctivochalasis excision, nine patients (50.0%) underwent lid surgery, five (27.8%) underwent dacryocystorhinostomy (DCR) surgery, one (5.6%) underwent both lid surgery and DCR, and four (22.4%) underwent only conjunctivochalasis surgery.. Following DCR surgery, five of six patients had a positive Valsalva bubble test (VBT).15 Of the eight patients who underwent preoperative Schirmers testing, only one suggested the presence of ocular surface drying.. Following surgery, 12 patients (66.7%) were happy with their surgical result. Three patients (16.7%) were substantially improved (70% better). One patient (5.6%) was not significantly improved and, despite being offered further surgery, did not ...
TY - JOUR. T1 - Reconstruction of the Corneal Epithelium by Limbal Allograft Transplantation for Severe Ocular Surface Disorders. AU - Tsubota, Kazuo. AU - Toda, Ikuko. AU - Saito, Hiroshi. AU - Shinozaki, Naoshi. AU - Shimazaki, Jun. PY - 1995/1/1. Y1 - 1995/1/1. N2 - Purpose: Although penetrating keratoplasty is an established surgical procedure, it often is ineffective for severe ocular surface diseases such as alkali burns or limbal deficiency. The authors have performed limbal allograft transplantation for the reconstruction of the corneal epithelium. Methods: A total of nine patients (3 with chemical injury, 3 with limbal deficiency with unknown etiology, 2 with moderate ocular pemphigoid [OCP], and 1 with traumatic limbal deficiency) were treated by limbal allograft transplantation. Penetrating keratoplasties were performed in all patients with the exception of one with OCP. Patients received cyclosporine both systemically (10 mg/kg) and topically (0.05%) as well as high-dose intravenous ...
Conjunctival chalasis, or conjunctivochalasis (Cch), is a commonly observed condition in our everyday patient care experiences. Because it is so common, and because a majority of patients are asymptomatic, optometrists seldom feel the need treat.
Abstract: : Purpose: Pharmacologic approaches using anti-angiogenesis agents may be helpful for the treatment of choroidal neovascularization. The delivery of drugs into the choroid and subretinal space may be safer and more effective using sustained-release implants placed in the subconjunctival space versus surgical implantation directly into the vitreous cavity. We investigated the ocular distribution of a lipophilic fluorescent compound, 5-hexadecanoylaminofluorescein (H-110, MW= 586), from a sustained-release device placed in the subconjunctival space to determine the feasibility of using this approach for drug delivery into the vitreou Methods: We used the lipophilic fluorescent compound to construct sustained-release matrix implants to produce slow rates of drug release for a prolonged period time. Three types of matrices were formed by combining the compound with either polyvinyl alcohol, hydropropyl cellulose (HPC), or silicone. The in vitro release rates of the three different implant ...
Recorded on Saturday, October 28, 2017. Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA (Auditorium -- 8th Floor). Christopher J. Rapuano, MD - Program Chair. Last Review Date - October 28, 2017. Course Description: The management of ocular surface disease is often complicated, including seeking the presence of an underlying systemic condition, the use of topical and occasionally oral medications to control the inflammation and improve the health of the cornea and conjunctiva. This conference will review the current strategies for evaluation and management of these patients. At the conclusion of this conference, participants should be able to:. Evaluate patients with ocular surface disease in a systematic fashion. Develop a strategy to best manage patients with a variety of ocular surface conditions. Assess the rationale for medical & surgical treatment of conjunctivochalasis Counsel patients undergoing cataract surgery as to the effect of their OSD on their outcomes. Accreditation ...
Transparency of the cornea, our window to the world, and functionality of the neighbouring conjunctiva are critical for vision. Compromise of the various stem cells that maintain these tissues can lead to blindness. The Cells for Sight Team is aiming to understand the biology and therapeutic potential of stem cells (and the cells with which they interact) to develop and deliver novel cell-based therapies and anti-scarring strategies for patients with blinding corneal and conjunctival disease ...
chemosis - MedHelps chemosis Center for Information, Symptoms, Resources, Treatments and Tools for chemosis. Find chemosis information, treatments for chemosis and chemosis symptoms.
The presentation in this case was similar to that described in a previous case series of hypersensitivity reactions to hyaluronidase following peribulbar anaesthetic for cataract surgery.(7) The typical presenting features in this case series were proptosis, peribulbar erythema and itching, restriction of extraocular muscle function, conjunctival chemosis, pain and itch. The management in this case involved observation and oral anti-histamines. Complete resolution occurred over the following 7 days ...
The diagnosis of chemosis will consist of a series of questions about intensity, irritation, pain, watering and exudation of fluid from the eyes, as well as any other presenting symptom. It is also important to disclose any allergies or previous medical conditions that you may have.. A thorough examination of the eyes will also be carried out, which will involve the use of specialized ophthalmological equipment to see the extent of ocular pathology. If necessary, your doctor may also suggest obtaining imaging studies of the eye or biopsy in cases where a tumor is suspected. ...
Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) syndrome is a rare primary headache syndrome first described in 1978. We report on a 43-year-old man with a 10 year history of SUNCT in whom a pituitary macroadenoma was eventually detected. His pain rapidly improved with medical treatment of the prolactinoma and we propose that this is a case of symptomatic SUNCT.. ...
Attacks fulfilling criteria for 3.3 Short-lasting unilateral neuralgiform headache attacks, and criterion B below B. Only one or neither of conjunctival…
Even though a subconjunctival hemorrhage can be a benign finding, there are many conditions that can cause hemorrhages that deserve investigation. If youve had a recent trauma, you definitely need to see a doctor in case there is an open abrasion or maybe even a deeper injury that needs treatment. Blood pressure should be checked when a subconjunctival hemorrhage appears without history of trauma - a study of 78 patients with spontaneous presentation of subconjunctival hemorrhage (average age 53) showed that 46% of patients with subconjunctival hemorrhage had elevated blood pressure. If you have recurrent subconjunctival hemorrhages, having blood work done to test for dangerous systemic conditions is a good idea. In addition to checking blood pressure and blood sugar, your doctor may order blood work to rule out anemia, leukemia, and blood clotting disorders like polycythemia. Most of the time subconjunctival hemorrhages are just an annoyance, but they can be a sign of a deeper health problem ...
Usually, treatment is unnecessary. A subconjunctival hemorrhage will resolve on its own. Your doctor may recommend that you use artificial tears several …. Subconjunctival hemorrhage is a broken blood vessel in the eye - Learn more about this common, harmless condition that clears up without treatment.. Subconjunctival Hemorrhage Overview. The conjunctiva is the thin, moist, transparent membrane that covers the white part of the eye (called the sclera) and …. Amaryl Diabetes Side Effects Metformin Side Effects: An Introduction As with any medicine, there are possible side effects with metformin (Glucophage ®) or metformin ER (Glucophage XR® Amaryl (glimepiride) is a prescription drug used to control. What causes a subconjunctival hemorrhage? … The conjunctiva contains nerves and many small blood vessels. These blood vessels are usually barely visible …. Most of the time, no symptoms are associated with a subconjunctival hemorrhage other than seeing blood over the white part of the eye. ...
The specific cause of subconjunctival hemorrhage is not always apparent. Extremely delicate, the blood vessels of the eyes rupture easily and can break under the pressure of a powerful sneeze, violent coughing, vomiting, or strain from activities like weight lifting. Subconjunctival hemorrhage can also result from an injury to the eye in cases of excessive eye rubbing, inserting contact lenses, or through some other trauma. In addition, a viral or bacterial infection of the eye such as conjunctivitis can cause a subconjunctival hemorrhage.. Certain medications or medical conditions can predispose an individual to recurrent subconjunctival hemorrhages. These conditions include diabetes, high blood pressure or hypertension, blood clotting disorders, and blood thinning medications like aspirin or Coumadin.. ...
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Subconjunctival hemorrhage, also known as subconjunctival haemorrhage and hyposphagma, is bleeding underneath the conjunctiva. The conjunctiva contains many small, fragile blood vessels that are easily ruptured or broken. When this happens, blood leaks into the space between the conjunctiva and sclera. Such a hemorrhage may be caused by a sudden or severe sneeze or cough, or due to high blood pressure or as a side effect of blood thinners such as aspirin or warfarin. It may also be caused by heavy lifting, vomiting, or even rubbing ones eyes too roughly. In other cases, it may result from being choked or from straining due to constipation. Also, it can result as a minor post-operative complication in eye surgeries such as LASIK. Whereas a bruise typically appears black or blue underneath the skin, a subconjunctival hemorrhage initially appears bright-red underneath the transparent conjunctiva. Later, the hemorrhage may spread and become green or yellow, like a bruise. Usually this disappears ...
Causes of Subconjunctival hemorrhage including triggers, hidden medical causes of Subconjunctival hemorrhage, risk factors, and what causes Subconjunctival hemorrhage.
Find the best subconjunctival hemorrhage doctors in Bangalore. Get guidance from medical experts to select subconjunctival hemorrhage specialist in Bangalore from trusted hospitals - credihealth.com
What is a Subconjunctival Hemorrhage?A subconjunctival hemorrhage is the medical term used to describe a break in the blood vessels beneath the conjunctiva of the eye. Anytime you see visible blood in your eye, seek medical treatment from your eye doctor immediately.. What are the Symptoms of a Subconjunctival Hemorrhage?. Red, bloody appearing eye.. How Common are Subconjuntival Hemorrhages?. Subconjunctival hemorrhages are fairly common, especially in people who participate in activities that result in blows to the eye such as boxing.. What Causes Subconjunctival Hemorrhages?. Eye trauma. Heavy lifting, coughing, sneezing or laughing. Constipation. Blood thinner medications. Vitamin K deficiency. How is a Subconjunctival Hemorrhage Diagnosed?. Diagnosing a subconjunctival hemorrhage begins with a comprehensive eye exam at Ducklo EyeCare.. During this exam, your doctor uses tests to evaluate your conjunctiva to determine the extent of the hemorrhage and to asses if it is causing any decrease in ...
The elective use of aspirin and NSAIDs is typically discouraged. A common symptom of a subconjunctival hemorrhage, itchy eyes, is often treated by applying eye drops or artificial tears to the affected eye(s), however, this is discouraged, as it may slow down the healing process. lacrimal system: Dacryoadenitis · Epiphora · Dacryocystitis · Xerophthalmia orbit: Exophthalmos · Enophthalmos Other strabismus: Esotropia/Exotropia · Hypertropia · Heterophoria (Esophoria, Exophoria) · Brown s syndrome · Duane syndrome Other binocular: Conjugate gaze palsy · Convergence insufficiency · Internuclear ophthalmoplegia · One and a half syndrome . When this happens, blood leaks into the space between the conjunctiva and sclera. Whereas a bruise typically appears black or blue underneath the skin, a subconjunctival hemorrhage initially appears bright red underneath the transparent conjunctiva ...
A subconjunctival haemorrhage is one cause of a red eye. It is caused by a small bleed behind the conjunctiva. About Subconjunctival Haemorrhage
This week, the Doctors discuss a Viewer question regarding a Kidney mass where the doctor is monitoring the growth. After monitoring the growth they discover Spicules On Lung Scan. Is it Small Cell Lung Cancer? Will they have to Remove the Kidney. What is the Survival Rate Of Lung Cancer and of Kidney Cancer? They also touch on A question regarding Having multiple Bloody eyes over the course of 6 weeks. What is a subconjunctival hemorrhage? How Common are they? What causes subconjunctival hemorrhages? Is it a sign of something bigger happening in the body? What are the causes of psoriasis? The Doctors also touch on the latest Covid-19 news for this week.. ...
Purpose : Whether ocular cicatricial pemphigoid (OCP) treated with stepladder immunomodulatory therapy (IMT) can achieve complete remission is not clear. We performed a retrospective, observational clinical study to evaluate the possibility of long-term complete remission of OCP after withdrawal of IMT. Methods : The authors studied the long-term remission off IMT in 34 patients with biopsy proven OCP between January 2005 and October 2015, 25 men and 9 women . The mean age at onset for OCP was 67.0 years. The long-term complete remission off IMT for OCP was defined as patients with OCP who were withdrawn off IMT for at least 1 year with absence of progressive scarring and active ocular inflammation. The average follow up was 5 years. Demographic, treatment regimen, conjunctival inflammation, stage of OCP (Foster), and best corrected visual acuity were recorded. Results : All 34 patients achieved a clinical long-term remission without IMT. Average sustained remission time was 3 years (from 1 year ...
A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Ocular cicatricial pemphigoid
Background: Until recently, synthetic fiber conjunctival granuloma (SFCG) is rarely reported and has been poorly understood. Our study was to explore the clinical features, histopathologic characteristics, surgical outcomes, and prognosis of SFCG after surgical excision.|stron...
The conjunctiva is a relatively loose structure and any bleeding can easily spread and appear quite alarming. Patients are, however, often asymptomatic and may only become aware of having a red eye when looking in the mirror or having it pointed out to them.. The majority of subconjunctival haemorrhages occur spontaneously without an identifiable cause, the patient occasionally complaining of a sudden popping feeling in the eye. It is likely that many of these patients may have had mild trauma eg eye rubbing, which has contributed to the bleed.. ...
What is that red spot on my eye? Many patients will report visualizing a bright red spot on the white part of their eye when they look in the mirror. Some patients state that family or friends noticed this problem and they were unaware of it. This is typically known as a subconjunctival hemorrhage. We need to think of this condition like a broken blood vessel. The blood gets trapped between the outer conjunctival membrane and the sclera (white part of the eye). There typically is no pain, irritation or change in vision. It usually occurs in one eye but patients can present with hemorrhage in both eyes.. What causes this hemorrhage? It can occur from activities associated with straining such as coughing, vomiting, sneezing or lifting something heavy just to name a few stressful activities. Occasionally, uncontrolled hypertension or diabetes can be associated. Some patients on blood thinners (Coumadin) or aspirin products may be more prone.. It is often worthwhile to have an initial eye exam to ...
What is that red spot on my eye? Many patients will report visualizing a bright red spot on the white part of their eye when they look in the mirror. Some patients state that family or friends noticed this problem and they were unaware of it. This is typically known as a subconjunctival hemorrhage. We need to think of this condition like a broken blood vessel. The blood gets trapped between the outer conjunctival membrane and the sclera (white part of the eye). There typically is no pain, irritation or change in vision. It usually occurs in one eye but patients can present with hemorrhage in both eyes.. What causes this hemorrhage? It can occur from activities associated with straining such as coughing, vomiting, sneezing or lifting something heavy just to name a few stressful activities. Occasionally, uncontrolled hypertension or diabetes can be associated. Some patients on blood thinners (Coumadin) or aspirin products may be more prone.. It is often worthwhile to have an initial eye exam to ...
What is that red spot on my eye? Many patients will report visualizing a bright red spot on the white part of their eye when they look in the mirror. Some patients state that family or friends noticed this problem and they were unaware of it. This is typically known as a subconjunctival hemorrhage. We need to think of this condition like a broken blood vessel. The blood gets trapped between the outer conjunctival membrane and the sclera (white part of the eye). There typically is no pain, irritation or change in vision. It usually occurs in one eye but patients can present with hemorrhage in both eyes.. What causes this hemorrhage? It can occur from activities associated with straining such as coughing, vomiting, sneezing or lifting something heavy just to name a few stressful activities. Occasionally, uncontrolled hypertension or diabetes can be associated. Some patients on blood thinners (Coumadin) or aspirin products may be more prone.. It is often worthwhile to have an initial eye exam to ...
What is that red spot on my eye? Many patients will report visualizing a bright red spot on the white part of their eye when they look in the mirror. Some patients state that family or friends noticed this problem and they were unaware of it. This is typically known as a subconjunctival hemorrhage. We need to think of this condition like a broken blood vessel. The blood gets trapped between the outer conjunctival membrane and the sclera (white part of the eye). There typically is no pain, irritation or change in vision. It usually occurs in one eye but patients can present with hemorrhage in both eyes.. What causes this hemorrhage? It can occur from activities associated with straining such as coughing, vomiting, sneezing or lifting something heavy just to name a few stressful activities. Occasionally, uncontrolled hypertension or diabetes can be associated. Some patients on blood thinners (Coumadin) or aspirin products may be more prone.. It is often worthwhile to have an initial eye exam to ...
Subconjunctival Hemorrhage (Blood in the eye) Causes, Home Remedies, Treatment Red Eye, Increased pressure on the blood vessels may lead to its rupture and bleeding. The reason for the veins to bleed can be by the pressure caused due to sneezing
Blood in the eyes is medically known as a subconjunctival hemorrhage. The bleeding results from a break in a small blood vessel in the white of the eye.
Subconjunctival Hemorrhage in Rochester, NY. Alexander Eye Associates & Optical is your local Optometrist in Rochester serving all of your needs. Call us today at (585) 325-3070 for an appointment.
This is a condition where there is a small bleed from a tiny blood vessel beneath the clear membrane that covers the white part of the eye. Since the membrane is clear, and the space beneath it is small, the blood spreads and is highly visible and dramatic in appearance.. Subconjunctival haemorrhage may occur following trauma, eye surgery and eye injections.. In the vast majority of cases, this is spontaneous and harmless. The blood clears over a period of a week or two, gradually turning yellow and disappearing.. ...
Subconjunctival hemorrhage is a broken blood vessel in the eye - Learn more about this common, harmless condition that clears up without treatment.
Subconjunctival Hemorrhage in Ocala, FL. Eye Care Center of Ocala is your local Optometrist in Ocala serving all of your needs. Call us today at 352-512-0560 for an appointment.
A subconjunctival hemorrhage is when a blood vessel breaks open in the white of the eye. It causes a bright red patch in the white of the eye. It is similar to a bruise on the skin.
That is the word for the day. Actually Subconjunctival hemorrhage is my word of the month! Had to go thru this twice in a row last week. I have to keep a close eye on my food intakes since I read that there are a lot of factors that might cause the blood vessels in my eyes to burst like that and goes away in about 1 week ...
Subconjunctival Hemorrhage in Hillsboro, OR. Sunset Vision Center is your local Optometrist in Hillsboro serving all of your needs. Call us today at (503) 844-6858 for an appointment.
A subconjunctival hemorrhage is similar to an ordinary bruise on the skin - its like a bruise of the eye. It usually appears as a single, concentrated spot of
Subconjunctival Hemorrhage in Monaca, PA. OPTOMETRIC CARE INC is your local Optometrist in Monaca serving all of your needs. Call us today at (724) 774-7232 for an appointment.
Thanks for your Question. Most likely you have inflamed pinguecula and at this stage i dont see the reason behind the blood tests.. FML is a weak corticosteroid and it might be helpful to treat inflamed pinguecula but sometimes you need a stronger corticosteroids to treat the inflammation such as lotemax, tobradex or pred forte eye drops. These eye drops should be used only under the instructions of your eye doctor.. These eye drops wont cure the pinguecula, they will only treat the redness and pain from the inflammtion and should be stopped once the inflammation is gone. The only cure for pinguecula is surgical removal.. One of the causes of pinguecula is sunlights and UV Lights so it would be helpful to wear sunglasses outdoors. Try to use preservative free lubricant eye drops as they can help to reduce inflammation.. ...
Shunting to the subconjunctival space involves the mechanism of diverting aqueous humor to the subconjunctival space from an ab interno stent placed in the angle through a clear corneal incision. The device was created to solve a major problem with tube shunts and trabeculectomy, which is that pressure can reduce, but prevention of hypotony relies on subjective scarring and suture tightness. Shunting to the sub conjunctiva was designed to prevent excessively low pressures and reduce reliance on subjective measures to dictate flow. A bleb is created but it is a more diffuse, low, and less cystic bleb than that with a trabeculectomy. A comfort level with treating blebs post-operatively, such as needling, is required so likely glaucoma specialists and those comfortable with trabeculectomies will find the benefit of this procedure most.. ...
A 13-day-old baby, born of a full term, uncomplicated, normal vaginal delivery at a primary healthcare centre presented with severe bilateral proptosis. At 12 h postpartum a presumed subconjunctival haemorrhage was seen on the temporal aspect of the right eye following which bilateral, rapid onset, painless proptosis developed.. At presentation in the department of ophthalmology CSMMU Lucknow, the child had bilateral, severe, axial, non-pulsatile, almost symmetrical proptosis, along with forniceal prolapse, conjunctival chemosis and exposure keratopathy. The ocular movements were restricted in all directions in both the eyes. There was no fundal view because of the severe exposure keratopathy (figure 1A). The systemic examination was normal and no evidence of bleeding diathesis or battering was found. ...
Looking for online definition of symblepharon in the Medical Dictionary? symblepharon explanation free. What is symblepharon? Meaning of symblepharon medical term. What does symblepharon mean?
A small sample of tissue (biopsy) is taken from the eyes and usually also the mouth. These biopsies are evaluated under a fluorescence microscope and tested for antibodies associated with MMP. Whilst biopsies from skin and mouth MMP lesions are less than 10% likely to give false negative results, unfortunately biopsies from the eye can give a false negative result in 30-50% of cases. So a positive result from the eye confirms the diagnosis, but a negative result from the eye does not necessarily mean that the diagnosis is not MMP. In a proportion of patients with negative biopsy results, treatment with immunosuppressive therapy (which suppresses an overactive immune system) in a similar manner to patients with positive biopsy results, may be necessary.. A blood test may also be used to detect the antibodies in the circulation, but they are detectable in less than 30% of ocular MMP patients.. If it is likely that you will require immunosuppressive medication (which suppresses an overactive immune ...
TY - JOUR. T1 - Evaluation and treatment of children with ocular rosacea. AU - Donaldson, Kendall E.. AU - Karp, Carol L.. AU - Dunbar, Mark T.. PY - 2007/1/1. Y1 - 2007/1/1. N2 - PURPOSE: To describe the clinical presentation and treatment of ocular rosacea in children, an often unrecognized entity. METHODS: Retrospective chart review of 20 patients (age, 22 months to 17 years) who presented during childhood with corneal pathology, lid margin disease, and skin changes consistent with ocular rosacea. All patients were evaluated by the Cornea/External Disease Division of a tertiary-care facility, Bascom Palmer Eye Institute, Miami, FL, between 1990 and 2003. RESULTS: Sixty percent of patients improved after treatment with systemic erythromycin or doxycycline and topical low-dose steroid preparations. Ten percent of patients experienced no change in symptoms with treatment, and 30% of patients had incomplete follow-up to determine success of treatment. The patients maintained remission for up to 4 ...
TY - JOUR. T1 - Association of human antigen class i genes with cold medicine-related Stevens-Johnson syndrome with severe ocular complications in a Korean population. AU - Jun, Ikhyun. AU - Rim, John Hoon. AU - Kim, Mee Kum. AU - Yoon, Kyung Chul. AU - Joo, Choun Ki. AU - Kinoshita, Shigeru. AU - Seo, Kyoung Yul. AU - Ueta, Mayumi. PY - 2019/4/1. Y1 - 2019/4/1. N2 - Background/aims Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are a spectrum of diseases that cause an acute vesiculobullous reaction in the skin and mucous membranes. The occurrence of these diseases is associated with various drugs, a large proportion of which is comprised cold medicines (CM). We try to investigate the association between human leucocyte antigen (HLA) class I genes and CM-related SJS/TEN (CM-SJS/TEN) with severe ocular complications (SOC) in the Korean population. Methods This multicentre case-control study enrolled 40 Korean patients with CM-SJS/TEN with SOC and 120 age-matched and ...
Three children with an unusual but clearly defined combination of clinical findings that appear to have been inherited in an autosomal recessive manner are described. All had developed laryngeal abnormalities, chronic skin ulceration, nail dystrophy, and conjunctival disease in infancy. In every case, dental enamel was hypoplastic and both skin and mucosal surfaces demonstrated increased susceptibility to trauma. Progression of disease occurred, to life threatening respiratory obstruction in two cases and to effective blindness and fatal respiratory obstruction in the third child. All of these children came from the Pakistani ethnic group. No medical treatment has halted progression of this disease but laser therapy has been partially successful in alleviating laryngeal manifestations. Ultrastructural and immunohistological examination of unaffected skin was undertaken in each child. No abnormality was found in the child with the mildest clinical disease. Both of the other children showed ...
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DefinitionSubconjunctival hemorrhage is a bright red patch appearing in the white of the eye. This condition is one of several disorders called red eye.
Bloodshot eyes arent exactly the best feature of a person! When a persons eyes are bloodshot, it is quite easy to see that something is wrong! ...
1. Septicemic stage: presents abruptly with fevers, headache, severe myalgias, rigors, prostration, and sometimes circulatory collapse; conjunctival suffusion is common; skin rash, pharyngitis, lymphadenopathy, hepatomegaly, splenomegaly ...
Pinguecula is an abnormal eye growth - if youre in Jacksonville and think you may have Pinguecula, contact Nicolitz Eye Consultants for an examination.
Miosis is often accompanied by complaints of pain, dim vision, blurred vision, conjunctival injection, nausea, and occasionally vomiting. The pain may be sharp or dull in or around the eyeball, but more often is a dull ache in the frontal part of the head. Dim vision is due in part to the small pupil, and cholinergic mechanisms in the visual pathways also contribute. The complaint of blurred vision is less easily explained, as objective testing usually indicates an improvement in visual acuity because of the pin-hole effect. Conjunctival injection may be mild or severe, and occasionally subconjunctival hemorrhage is present. Nausea (and sometimes vomiting) are part of a generalized complaint of not feeling well. Miosis, pain, dim vision, and nausea can be relieved by topical homatropine or atropine in the eye ...
Figure 1A: Bulbar conjunctiva of the left eye imaged in a 50 degrees red-free mode with the RFI. Temporal conjunctiva of the patients left eye with microangiopa
Ocular rosacea may be more common than widely believed, according to Dr. Guy Webster, professor of dermatology at Thomas Jefferson University, Philadelphia, who spoke at the recent American Academy of Dermatology annual meeting in San Francisco. Dr. Webster, whose practice is located near an eye hospital, said about half of his rosacea patients have eye symptoms. The ocular symptoms are often subtle, however, and many patients do not even know they have a problem. Its only after being treated that they realize rosacea had affected their eyes, he said.
Compare risks and benefits of common medications used for Ocular Rosacea. Find the most popular drugs, view ratings, user reviews, and more...
It results either from disease (conjunctival sequelae of trachoma) or trauma. Cicatricial pemphigoid and, in severe cases, ... Ankyloblepharon Holsclaw, DS (1998). "Ocular cicatricial pemphigoid and its treatment is surgery by conjunctival rotate graft ...
... tacrolimus eye drops in eyes with severe allergic conjunctival diseases". Journal of Natural Science, Biology and Medicine. 17 ... Contraindications and precautions include: Hepatic disease Immunosuppression Infants Infection Neoplastic disease, such as: ... exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and ... The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. ...
"Conjunctival flaps in the treatment of corneal disease with reference to a new technique of application". AMA Arch Ophthalmol. ... Cornea & External Disease Archived 2014-03-27 at the Wayback Machine, at the New York Eye and Ear Infirmary; by Mark Speaker ... A Gundersen flap, also known as Gundersen's flap, Gundersen's conjunctival flap, or conjunctivoplasty, and often misspelled ... Gunderson, is a surgical procedure for correcting corneal disease. It involves excising a damaged section of cornea, and ...
Conjunctival incisional biopsy is occasionally done when granulomatous diseases (e.g., sarcoidosis) or dysplasia are suspected ... Conjunctivitis is the most common eye disease. Rates of disease is related to the underlying cause which varies by the age as ... 2015). Epidemiology and Prevention of Vaccine-Preventable Diseases. U.S. Dept. of Health & Human Services, Centers for Disease ... If due to a chemical splash, it is often present in only the lower conjunctival sac. With some chemicals, above all with ...
... also known as Weil's disease) develop conjunctival suffusion. When it does occur, it develops towards the end of the early ... Conjunctival suffusion may also occur in patients with a Hantavirus infection. In a 1994 study of 17 patients with Hantavirus ... Conjunctival suffusion is characterized by redness of the conjunctiva that resembles conjunctivitis, but it does not involve ... Conjunctival suffusion is an eye finding occurring early in leptospirosis, which is caused by Leptospira interrogans. ...
... are chronic allergic diseases wherein eosinophils, conjunctival fibroblasts, epithelial cells, mast cells, and TH2 lymphocytes ... VKC is a disease of childhood and is prevalent in males living in warm climates. AKC is frequently observed in males between ... Allergic conjunctivitis is common in people who have other signs of allergic disease such as hay fever, asthma and eczema.[ ... Symptoms of the aforementioned ocular diseases include itching and pink to reddish eye(s). These two eye conditions are ...
Runny eyes and other conjunctival problems can be caused by dental disease or a blockage of the tear duct. Environmental ... Rabbit hemorrhagic disease (RHD), also known as viral hemorrhagic disease (VHD) or rabbit calicivirus disease (RCD), is caused ... "Rabbit Hemorrhagic Disease: Viral Hemorrhagic Disease of Rabbits, Rabbit Calicivirus Disease" (PDF). CFSPH.IAState.edu. Iowa ... as it may hide signs of disease and is not considered a practical response for such a rapidly spreading disease. In the UK, ...
... and conjunctival cicatricial disease, with visual loss. Kohl was used not only as a cosmetic but also as a medicinal collyrium ... There are a number of endemic ocular diseases in the Nile region including trachoma - which is caused by a chlamydial bacterium ... use of kohl across the Mediterranean and the Middle East attests to its ability to protect the eye from infectious disease and ...
... further study over longer follow-up periods with somewhat better results occurring in patients with conjunctival disease; and 5 ... Disease that moves past a localized stage to become disseminated, rapidly progressive disease, and symptomatic disease have ... where the bacterium has not been associated with the disease. Treatment of Borrelia burdorferi-negative disease or disease for ... Patients with extensive disease or disease that has progressed to a higher grade lymphoma (principally diffuse B-cell lymphoma ...
Risk factors for the disease are exposure to sun (specifically occupational), exposure to UVB, and light-colored skin. Other ... Conjunctival squamous cell carcinoma (conjunctival SCC) and corneal intraepithelial neoplasia comprise what are called ocular ... Treatment of conjunctival SCC is usually surgical excision followed by cryotherapy. After this procedure, Conjunctival SCC can ... Mortality for conjunctival SCC ranges from 0-8%. Diagnosis is often made by biopsy, as well as CT (in the case of invasive SCC ...
Bilateral conjunctival inflammation has been reported to be the most common symptom after fever. It typically involves the ... Children with Kawasaki disease should be hospitalized and cared for by a physician who has experience with this disease. In an ... Kawasaki disease is predominantly a disease of young children, with 80% of patients younger than five years of age. About 2,000 ... "BBC Health: Kawasaki Disease". 31 March 2009. Archived from the original on 9 February 2011. "Rare heart disease rate doubles ...
Other ocular findings can include conjunctival and retinal vascular abnormalities and anterior/posterior spoke-like cataract. ... Fabry disease, also known as Anderson-Fabry disease, is a rare genetic disease that can affect many parts of the body, ... Fabry disease is one of a group of conditions known as lysosomal storage diseases. The genetic mutation that causes Fabry ... Many disease-causing mutations have been noted. Kidney biopsy may also be suggestive of Fabry disease if excessive lipid ...
Symptoms include prostration, dyspnea, edema, conjunctival injection, viral exanthema, and CNS symptoms, including encephalitis ... Center for Disease Control, Marburg Haemorrhagic Fever. Center for Disease Control, Known Cases and Outbreaks of Marburg ... MVD is clinically indistinguishable from Ebola virus disease (EVD), and it can also easily be confused with many other diseases ... Martini, G. A. (1971). "Marburg Virus Disease. Clinical Syndrome". In Martini, G. A.; Siegert, R. (eds.). Marburg Virus Disease ...
Conjunctival limbal autograft (CLAU) involves transplantation of limbal tissue from a patient's healthy eye. As the procedure ... However, further surgical intervention may be needed if these approaches are unsuccessful, or when disease is more severe. ... Types of surgeries: In the case of a partial LSCD:, a sequential sector conjunctival epitheliectomy (SSCE) can be performed to ... Additionally, these cells also prevent the conjunctival epithelial cells from migrating onto the surface of the cornea. Damage ...
... as well as through inhalation and conjunctival exposure. The rate that the virus can spread is highly influenced by its ... Pacheco's disease is a highly infectious and acute bird disease caused by a species of herpesvirus, Psittacid alphaherpesvirus ... If a bird survives Pacheco's disease, it may later develop internal papilloma disease in its gastrointestinal tract. Pacheco's ... "Hygiene Protocols for the Prevention and Control of Diseases (Particularly Beak and Feather Disease) in Australian Birds" (PDF ...
Conjunctival concretion - development of hard deposits under the eyelid (H15.0) Scleritis - a painful inflammation of the ... International Statistical Classification of Diseases (WHO ICD-10) - Diseases of the eye and adnexa (ICD-10 codes H00-H59) ... This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known ... World Health Organization ICD-10 codes: Diseases of the eye and adnexa (H00-H59). [1]. Retrieved 2010-07-28. International ...
... conjunctival injection, etc.) Class 3: Proptosis Class 4: Extraocular muscle involvement (usually with diplopia) Class 5: ... Less commonly, it has been known as Parry disease, Begbie disease, Flajan disease, Flajani-Basedow syndrome, and Marsh disease ... Graves' disease occurs in about 0.5% of people. Graves' disease data has shown that the lifetime risk for women is around 3% ... Since Graves' disease is an autoimmune disease which appears suddenly, often later in life, a viral or bacterial infection may ...
... including the conjunctival sign and iris atrophy are ocular manifestations that are strongly indicative of sickle cell disease ... Sickle cell disease is a systemic disease that affects several organs in the body. Management of the underlying disease can ... Numerous diseases that feature blood hyperviscosity similar to sickle cell disease can manifest as retinal venous tortuousity. ... Mutation at the 6th position of the beta chain is the cause of sickle cell disease. Due to sickle cell disease, vascular ...
March 2014). "Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity ... at KIR2DL2/KIR2DL3". PLOS Neglected Tropical Diseases. 8 (3): e2744. doi:10.1371/journal.pntd.0002744. PMC 3961204. PMID ...
Conjunctival biopsy may be advised if malignancy is suspected. Pingueculae may enlarge slowly over time, but it is a benign ... It may have an increased prevalence in Gaucher's disease. Diagnosis of pinguecula is usually done by an eye care professional ... A pinguecula is a common type of conjunctival stromal degeneration in the eye. It appears as an elevated yellow-white plaque in ... It is thought that the high reflectivity of the solid white scleral tissue underlying the conjunctival tissue may result in ...
He discovered this disease was caused by two bacteria. The first, and more serious strain was caused by a "gonococcus-like ... Weeks, J.E. "The bacillus of acute conjunctival catarrh, or 'pink eye'." Archive Ophthalmology 15 (1886): 441-51. Pittman, ... Sao Paulo is one of the most developed states in Brazil, which makes it easier to receive reports of outbreaks of diseases like ... Under the German Cholera Commission of Egypt, Koch studied 50 patients in Egypt who were suffering from Egyptian eye disease. ...
During the initial stages of the disease, the patient could experience: fever nausea vomiting loss of appetite conjunctival ... The disease was first discovered in North America and since then has been identified in almost every corner of the earth. The ... The Centers for Disease Control and Prevention states that the diagnosis of Rocky Mountain Spotted Fever must be made based on ... Since R. rickettsii needs a moving vector to contract the disease to a viable host it is more likely that this pathogen has ...
... conjunctivitis 372.4 Pterygium 372.5 Conjunctival degenerations and deposits 372.6 Conjunctival scars 372.7 Conjunctival ... 335 Anterior horn cell disease 335.0 Werdnig-Hoffmann disease 335.1 Spinal muscular atrophy 335.2 Motor neurone disease 335.8 ... Myelopathy in other diseases classified elsewhere 336.8 Other myelopathy 336.9 Unspecified diseases of spinal cord 337 ... Polyneuropathy in malignant disease (140-208†) 357.4* Polyneuropathy in other diseases classified elsewhere 357.5 Alcoholic ...
... and unspecified protein-calorie malnutrition 264 Vitamin A deficiency 264.0 With conjunctival xerosis 264.1 With conjunctival ... Disorders of carbohydrate transport and metabolism 271.0 Glycogenosis Von Gierke's disease McArdle's disease Pompe's disease ... 272.6 Lipodystrophy 272.7 Lipidoses Gaucher's disease Niemann-Pick disease Sea-blue histiocyte syndrome 272.8 Other disorders ... This is a shortened version of the third chapter of the ICD-9: Endocrine, Nutritional and Metabolic Diseases, and Immunity ...
James WD, Berger TG, Elston DM, Odom RB (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN ... 978-0-7216-2921-6. Shields C, Shields J (2008). Eyelid, conjunctival, and orbital tumors: atlas and textbook. Hagerstwon, MD: ... is a deposition of yellowish cholesterol-rich material that can appear anywhere in the body in various disease states. They are ... and within the same disease spectrum as eruptive xanthomata. Other types of xanthoma identified in the Medical Dictionary ...
In addition, conjunctival resection can be performed to temporarily remove local inflammatory mediators, followed by the use of ... PUK is associated with different ocular and systemic diseases. Mooren's ulcer is a common form of PUK. The majority of PUK is ... Wegner's granulomatosis: WG is a rare autoimmune disease associated with PUK. It causes vasculitis of the lower and upper ... Rheumatoid arthritis: Approximately 50% of PUK are related to collagen vascular diseases, in which RA is the most common ...
... may have potential use for the treatment of liver disease and liver cancer. Tetrandrine has potential therapeutic ... value to prevent excess scarring/fibrosis in conjunctiva following trabeculectomy or in patients with severe conjunctival ... "Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment". Science. 347 (6225): 995-998 ...
After an acute flare-up, no clinical signs of disease may be seen for a prolonged period, which can vary from a few hours to a ... Other ocular problems may also occur, including conjunctival and corneal oedema, and aqueous flare. ... If the disease is not properly treated, it will eventually lead to blindness. ERU occurs in horses worldwide, but is more ... Horses that suffer from this disease can never be considered cured, although they can be managed by careful use of the therapy ...
Farber's disease: Nodular corneal opacity may be seen in association with this rare autosomal recessive disease. Acquired ... Congenital corneal ulcers: Unilateral corneal opacity may occur in association with conjunctival injection and other signs of ... diseases of the eye (22 ed.). pp. 195, 221. ISBN 978-81-312-3818-9. AK Khurana. "Diseases of the Cornea". Comprehensive ... It is a rare autosomal dominant disease caused by mutations in the DCN gene. In this bilateral Snowflake, whitish opacities ...
Diseases caused by poxviruses have been known for much of recorded history. Smallpox in particular has been highly prominent in ... and conjunctival illnesses, but occasionally cause more severe illnesses, such as hemorrhagic cystitis, hepatitis, and ... The most notable disease-causing viruses in Varidnaviria are adenoviruses, poxviruses, and the African swine fever virus (ASFV ... Many animal viruses in the realm are associated with disease, including adenoviruses, poxviruses, and the African swine fever ...
Eye diseases, Disorders of conjunctiva, Herpes simplex virus-associated diseases, Neonatology, Chlamydia infections, Gonorrhea) ... Signs and symptoms include:[citation needed] Pain and tenderness in the eyeball Conjunctival discharge: purulent, mucoid or ... List of systemic diseases with ocular manifestations "Conjunctivitis, Neonatal: Overview". eMedicine. 2019-05-30. Tan, Aik-Kah ... "Chlamydia trachomatis". In: Red Book: 2015 Report of the Committee on Infectious Diseases, 30th, Kimberlin DW (Ed), Elk Grove ...
Cannabis arteritis is a very rare peripheral vascular disease similar to Buerger's disease. There were about 50 confirmed cases ... congestion of the conjunctival blood vessels), a reduction in intra-ocular pressure, muscle relaxation and a sensation of cold ... and contribute to increased diagnoses of cardiovascular diseases and respiratory diseases among tobacco smokers. Cannabis smoke ... The association with these diseases has only been reported in cases where people have smoked cannabis. The authors cautioned ...
Sometimes, the disease appears very rapidly, especially after cataract surgery procedures. A new treatment for this disease, as ... The ongoing scarring over the conjunctival dissipation segment of the shunt may become too thick for the aqueous humor to ... Glaucoma is a group of eye diseases that result in damage to the optic nerve (or retina) and cause vision loss. The most common ... "Glaucoma". Parsons' diseases of the eye (22nd ed.). Elsevier. 15 July 2015. pp. 288-295. ISBN 978-81-312-3818-9. Salmon JF. " ...
"Rodent-borne diseases". European Centre for Disease Prevention and Control. Retrieved 2018-06-04. Meyer, Barbara J; Schmaljohn ... Medicine portal Viruses portal 1993 Four Corners hantavirus outbreak Bat-borne virus Cocoliztli epidemics Conjunctival ... Canada Communicable Disease Report (Report). Vector-borne diseases in Canada. Vol. 41-6. Winnipeg, MB: National Microbiology ... While many hantaviruses cause either of the two diseases, some are not known to cause illness, such as the Prospect Hill ...
... disease, Filatov's disease, or fourth disease. However, in 1979, Keith Powell identified it as in fact the same illness as the ... including signs such as conjunctival redness and cracked lips), which can help distinguish this from scarlet fever. Toxic shock ... Kawasaki disease: Children with this disease also present a strawberry tongue and undergo a desquamative process on their palms ... Long-term complications as a result of scarlet fever include kidney disease, rheumatic heart disease, and arthritis. In the ...
... (SLK, Théodore's syndrome) is a disease of the eye characterized by episodes of recurrent ... Surgical treatment options include thermocauterization of the bulbar conjunctiva and conjunctival resection, typically under ... "Superior limbic keratoconjunctivitis , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". rarediseases. ... Passons, Gary A.; Wood, Thomas O. (1984-08-01). "Conjunctival Resection for Superior Limbic Keratoconjunctivitis". ...
"FDA Approves First Biosimilar to Treat Macular Degeneration Disease and Other Eye Conditions". U.S. Food and Drug ... The most common side effects in clinical trials were conjunctival haemorrhage, eye pain, vitreous floaters, increased ...
Diagnostic Atlas of Common Eyelid Diseases. CRC Press. 23 July 2007. ISBN 9781420016321. Clinical Ocular Pharmacology. Elsevier ... of corticosteroid injection include hypopigmentation and fat atrophy which is less likely to occur in conjunctival approach of ...
M. N. Naik, A. G. Nair, A. Gupta, S. Kamal: Minimally invasive surgery for thyroid eye disease. In: Indian J Ophthalmol. 63(11 ... A study published in 2017 documented fewer conjunctival and eyelid swelling complications in the immediate postoperative period ...
"Teashades" was also used to describe glasses worn to hide the effects of recreational drugs such as marijuana (conjunctival ... because sensitivity to light being one of the symptoms of the disease,[dubious - discuss] although no sources have been found ...
Until that time, the only effective remedy for an infectious disease was quinine, which was used to treat malaria.[citation ... and the Calmette conjunctival test. With experience gained from the tuberculin skin test during the greater part of the last ... 1982-03-01). "The Tuberculin Skin Test". American Review of Respiratory Disease. 125 (3P2): 108-118. doi:10.1164/arrd.1982.125. ... 1993). "The Tuberculin Skin Test". Clinical Infectious Diseases. 17 (6): 968-975. doi:10.1093/clinids/17.6.968. ISSN 1058-4838 ...
Such patients often give family history of other atopic diseases such as hay fever, asthma or eczema, and their peripheral ... Conjunctival epithelium undergoes hyperplasia and sends downward projection into sub-epithelial tissue. Adenoid layer shows ... Conjunctival vessels also show proliferation, increased permeability and vasodilation. Based on severity, authors have ... Eye diseases, Disorders of conjunctiva, Rare diseases). ...
The headache needs to take place with one of the following: Ipsilateral conjunctival injection and/or lacrimation Ipsilateral ... CPH is a long-term disease with symptoms lasting for longer than a year, either without remission or with remissions that last ...
Most frequently, there was no conjunctival flap. However, some especially skilled eye surgeons formed a conjunctival flap as ... Ultraviolet-rich India with its vast rural and underclass population afflicted with nutritional eye diseases combined with a ... multitude of public health problems was and still is the "Land of Eye Disease and Eye Surgery". Few Western ophthalmologists ...
Marshall Hall on Diseases of the Respiratory System; III. Hay Asthma". The Lancet. 30 (768): 245. doi:10.1016/S0140-6736(02) ... Characteristic physical findings include conjunctival swelling and erythema, eyelid swelling with Dennie-Morgan folds, lower ... With respect to what is termed the exciting cause of the disease, since the attention of the public has been turned to the ... the effluvium from hay has no connection with the disease. History of Allergy. Karger Medical and Scientific Publishers. 2014. ...
... hodgkin disease MeSH C04.557.386.390 - immunoproliferative small intestinal disease MeSH C04.557.386.480 - lymphoma, non- ... conjunctival neoplasms MeSH C04.588.364.659 - orbital neoplasms MeSH C04.588.364.818 - retinal neoplasms MeSH C04.588.364.818. ... marek disease MeSH C04.619.935.800 - sarcoma, avian MeSH C04.651.600.500 - multiple endocrine neoplasia type 1 MeSH C04.651. ... carcinoid heart disease MeSH C04.557.470.200.025.215 - carcinoma, acinar cell MeSH C04.557.470.200.025.220 - carcinoma, adenoid ...
... information about the virus could lead to a blood test or a vaccine that could improve the management of the disease or aid in ... "Human transcriptome subtraction by using short sequence tags to search for tumor viruses in conjunctival carcinoma". Journal of ... Bowen's disease, basal cell skin carcinoma, extrapulmonary small cell carcinoma, and EGFR mutation-driven non-small cell lung ... Emerging Infectious Diseases. 15 (3): 489-91. doi:10.3201/eid1503.081206. PMC 2681127. PMID 19239773. Mazzoni E, Rotondo JC, ...
... stimulates conjunctival cell glycoconjugate secretion and demonstrates therapeutic efficacy in a rat model of dry eye". ... being evaluated in two multi-center phase III clinical studies in the United States for the treatment of dry eye disease.[1] ...
2003). "Ocular TFF-peptides: new mucus-associated secretory products of conjunctival goblet cells". Adv. Exp. Med. Biol. 506 ( ... "TFF3 expression at the esophagogastric junction is increased in gastro-esophageal reflux disease (GERD)". Peptides. 25 (5): 771 ...
Thus, the proper term for the yellowing of "white of the eyes" is conjunctival icterus. A much less common sign of jaundice ... The word "jaundice" is from the French jaunisse, meaning "yellow disease". The most common signs of jaundice in adults are a ... These diseases may cause jaundice due to increased erythrocyte hemolysis: Sickle-cell anemia Spherocytosis Thalassemia Pyruvate ... Jaundice is commonly associated with severity of disease with an incidence of up to 40% of patients requiring intensive care in ...
Patients with renal disease should receive flucytosine cautiously and in reduced doses. Guidelines for proper dosing exist. ... Anaphylaxis: Sometimes cases of anaphylaxis consisting of diffuse erythema, pruritus, conjunctival injection, fever, abdominal ... particular if the disease is life-threatening. Serious fungal infections may occur in those who are immunocompromised. These ... Clinical Infectious Diseases. 62 (12): 1564-1568. doi:10.1093/cid/ciw151. PMC 4885648. PMID 27009249. Lisak, Robert P.; Truong ...
... refers to a group of diseases in dogs that affect the optic nerve and involve a loss of retinal ganglion cells ... The ongoing scarring over the conjunctival dissipation segment of the shunt may become too thick for the aqueous humor to ... Primary glaucomas occur in the absence of other eye disease, and are therefore presumed to be genetic in origin. The most ... Secondary glaucomas occur when other eye diseases alter the flow of aqueous humor either into or out of the eye. Veterinarians ...
... but research into BLV-related diseases has not been as extensive as that conducted into other viral diseases. Researchers have ... An unexpected clinical finding is protrusion of the conjunctival membrane, due to enlargement of retro-ocular lymph nodes. ... One can use the experience with BLV for understanding HTLV-I induced diseases like ATL (adult T-cell leukemia) and HAM/TSP ( ... No treatment is available for the disease. Testing and removing positive animals from the herd is one method of control. In ...
Cases of skin disease that may be inherited in this kind of mode include fabry disease, anhidrotic ectodermal dysplasia, ... The patients' eyes appear red due to the dilatation of superficial vessels and appearance of conjunctival plaques in their eyes ... Epidermolysis bullosa is a rare type of genodermatosis, people with this disease have blisters on their skin and this disease ... Cases of skin disease that may be inherited in this kind of mode include incontinentia pigmenti, focal dermal hypoplasia and so ...
West Nile Virus Infection and Conjunctival Exposure. Emerging Infectious Diseases. 2005;11(10):1648-1649. doi:10.3201/ ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... Centers for Disease Control and Prevention. Laboratory-acquired West Nile virus infections-United States, 2002. MMWR Morb ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
"Conjunctival Diseases" by people in Harvard Catalyst Profiles by year, and whether "Conjunctival Diseases" was a major or minor ... "Conjunctival Diseases" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Conjunctival Diseases" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Conjunctival Diseases". ...
... Synonym(s) - Disease, Conjunctival Broader term(s) * Eye Diseases. * Conjunctival Diseases ...
West Nile Virus Infection and Conjunctival Exposure. Emerging Infectious Diseases. 2005;11(10):1648-1649. doi:10.3201/ ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... Centers for Disease Control and Prevention. Laboratory-acquired West Nile virus infections-United States, 2002. MMWR Morb ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
Whereas Hodgkin lymphoma very rarely causes ocular disease, non-Hodgkin lymphoma (NHL) is the most common type of ocular ... MRI may miss the conjunctival disease. [37] Orbital lesions usually are hypointense [32] or isointense on T1-weighted MRI and ... The intracranial disease occurs in 56-85% of patients with ocular disease, and estimates suggest that 15-25% of patients who ... Advanced disease correlated with increased risk ratios of persistent disease at the final follow-up and lymphoma-related death. ...
Whereas Hodgkin lymphoma very rarely causes ocular disease, non-Hodgkin lymphoma (NHL) is the most common type of ocular ... MRI may miss the conjunctival disease. [37] Orbital lesions usually are hypointense [32] or isointense on T1-weighted MRI and ... The intracranial disease occurs in 56-85% of patients with ocular disease, and estimates suggest that 15-25% of patients who ... Advanced disease correlated with increased risk ratios of persistent disease at the final follow-up and lymphoma-related death. ...
Conjunctival Impression Cytology and Tear-Film Changes in Patients With Inflammatory Bowel Disease. ... To evaluate the ocular surface changes and tear-film functions in patients with inflammatory bowel disease (IBD). METHODS:. The ... dry eye was 52.6% and 20.8% in the IBD and control groups, respectively through TBUT (P=0.004). The Ocular Surface Disease ... The Schirmer I test, tear breakup time (TBUT), corneal and conjunctiva fluorescent staining, and conjunctival impression ...
Use of conjunctival material for grafting over areas of the eye denuded by removal of a pterygium, pseudopterygium or ... Use of conjunctival material for grafting over areas of the eye denuded by removal of a pterygium, pseudopterygium or ...
Categories: Conjunctival Diseases Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ...
... also known as Kawasaki disease, is an acute febrile illness of unknown etiology that primarily affects children younger than 5 ... Bilateral conjunctival injection. *Oral mucosal changes. *Peripheral extremity changes. Patients whose illness does not meet ... Content source: Centers for Disease Control and Prevention , National Center for Emerging and Zoonotic Infectious Diseases ( ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ...
206010051625 Conjunctival hyperaemia Diseases 0.000 description 2 * 229960001389 Doxazosin Drugs 0.000 description 2 ... 206010015150 Erythema Diseases 0.000 title claims abstract description 58 * 239000000203 mixture Substances 0.000 title claims ... 201000004700 rosacea Diseases 0.000 title claims abstract description 54 * 241001303601 Rosacea Species 0.000 title claims ... 206010037888 Rash pustular Diseases 0.000 description 2 * QIQXTHQIDYTFRH-UHFFFAOYSA-N Stearic acid Chemical compound data:image ...
Japanese guidelines for allergic conjunctival diseases 2017. Allergol Int. 2017 Apr;66(2):220-9.Full text Abstract ... Allergic eye disease: a clinical challenge. Clin Exp Allergy. 1998 Dec;28 Suppl 6:39-43. Abstract ... Adleberg JM, Wittwer C. Use of the polymerase chain reaction in the diagnosis of ocular disease. Curr Opin Ophthalmol. 1995 Jun ... Conjunctival squamous cell neoplasia associated with ocular cicatricial pemphigoid. Ophthalmic Plast Reconstr Surg. 2017 Nov/ ...
... is a multifactorial disease of the tears and the ocular surface that results in discomfort, visual disturbance, and tear film ... Intercellular adhesion molecule-1 (ICAM-1) may be overexpressed in corneal and conjunctival tissues in dry eye disease. The ... encoded search term (Dry Eye Disease (Keratoconjunctivitis Sicca)) and Dry Eye Disease (Keratoconjunctivitis Sicca) What to ... Dry Eye Disease (Keratoconjunctivitis Sicca) Medication. Updated: Jun 14, 2022 * Author: Trent Tsun-Kang Chiang, MD, MS; Chief ...
keywords = "Conjunctival diseases/therapy, Corneal diseases/therapy, Lacrimal apparatus/abnormalities, Ophthalmic solutions/ ... The purpose of this study is to review the recently published literature on ocular surface diseases treated with human ... Dive into the research topics of Autologous serum for ocular surface diseases. Together they form a unique fingerprint. ... The purpose of this study is to review the recently published literature on ocular surface diseases treated with human ...
Face and chest flushes and conjunctival injection are reported at the early stages of the disease development. Haemorrhagic ... The disease has the potential for nosocomial spread [5]; hospital transmission of disease is well documented in the Islamic ... The disease has a sudden onset of fever, malaise, weakness, irritability and headache, and severe limb and loin pain. Patients ... Emerging Infectious Diseases, 2007, 13(7):No.1097-1100.. *Gonzalez JP et al. A fatal case of Crimean-Congo haemorrhagic fever ...
Dry eye disease dosing for Xiidra (lifitegrast ophthalmic), frequency-based adverse effects, comprehensive interactions, ... ICAM-1 may be overexpressed in corneal and conjunctival tissues in dry eye disease; LFA-1/ICAM-1 interaction can contribute to ... Dry Eye Disease. Indicated for treatment of the signs and symptoms of dry eye disease (DED) ... The exact mechanism in dry eye disease is not known. Binds to the integrin lymphocyte function-associated antigen-1 (LFA-1), a ...
Diseases : Conjunctival Diseases, Conjunctivitis, Wound Healing: Delayed. Pharmacological Actions : Anti-Bacterial Agents ... Diseases : Asthma, Cardiovascular Diseases, Chickenpox, Colic, Conjunctivitis, Dysmenorrhea, Fever, Gastric Ulcer, Gout, ... Diseases : Cataract, Conjunctivitis, Diabetic Retinopathy, Glaucoma, Macular Degeneration, Pterygium, Uveitis. Pharmacological ... Diseases : Vernal Keratoconjunctivitis. Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-4 ...
Evaluation of ocular surface clinical parameters and conjunctival impression cytology of rheumatic disease associated dry eye ... Ocular Surface Disease Index (OSDI), and conjunctival IC. Laboratory tests for inflammatory activity were assessed by ... in AS and Disease Activity Score 28 (DAS 28) in RA analyzed disease activity parameters. Besides, the Health Assessment ... The prompt and maintained aqueous tear and conjunctival cytology recovery, especially the goblet cells, in patients submitted ...
Phase I/II study on kilovoltage surface brachytherapy in conjunctival cancer: preliminary results Gustavo R Sarria1, Gustavo J ... Figure 7. Estimated disease free survival curve.. The need for adjuvant therapy in conjunctival squamous cell carcinoma is ... One-year disease-free survival was 96.7%, at the time there being no recurrence of disease in the patients with a longer follow ... To discover the 5-year disease-free survival rate in patients diagnosed with ocular conjunctival squamous cell carcinoma, T1-T3 ...
Conjunctivitis is an inflammatory disease characterized by conjunctival erythema, swelling, and discharge. In this study ... and different pathologies including both benign and malignant diseases to the functional and esthetic aspects of the hard and ... disease condition and demographic characteristic of the patient. ... and/or treat a pathological condition such as disease or injury ...
Only one patient with conjunctival melanoma (7.1%) was found to have metastatic disease on PET/CT imaging. Abnormal foci were ... Methods: Fourteen patients with T3 (n = 13) and T4 (n = 1) conjunctival melanoma (as defined in Chapter 42 of the AJCC staging ... PET/CT images were studied for the presence and distribution of metastatic conjunctival melanoma (determined by standardised ... Results: Fourteen patients with conjunctival melanoma underwent PET/CT imaging. Seven were newly diagnosed (presurgical ...
65 64 50 Manifestation of systemic disease, conjunctival 65 64 68 Manifestation of skin disease, conjunctival 65 65 00 Hematoma ... disease 76 27 00 Disease, Coats 76 28 00 Disease, Eales 76 28 00 Eales disease 76 30 00 Retinopathy, central serous NOS 76 ... 77 00 72 Disease, optic nerve, type not specified, associated with demyelinating disease 77 00 72 Disease, optic nerve, type ... secondary to other eye disease. /Code also precipitating disease/ 74 89 56 Opacity, lens, diabetic (snowflake) 74 99 00 Disease ...
High throughput bioprinting of cell therapy vehicles to treat ocular diseases like conjunctival disorder ...
We report the case of a 13-month-old boy who developed right side parotitis as a first symptom of Kawasaki disease (KD). The ... On the 5th day of illness, he developed lip redness, conjunctival injection, reddening of the BCG injection site, and edema of ... H.-J. Do, J.-G. Baek, H.-J. Kim et al., "Kawasaki disease presenting as parotitis in a 3-month-old infant," Korean Circulation ... M. B. F. Son and J. W. Newburger, "Kawasaki disease," in Nelson Textbook of Pediatrics, pp. 1209-1214, 20th edition, 2016. ...
... and other conjunctival, corneal, optic nerve, and orbital inflammatory diseases). Patients known to have HIV infection were ... Non-infectious ocular inflammatory diseases provide a model system wherein the disease serving as the indication for ... These conclusions should be generalisable to other disease indications for immunosuppressive treatment unless a disease- ... A principal strength of this study was that the eye disease indication for use or non-use of immunosuppression was a non-lethal ...
Overt Disease. Significant Clinical Manifestations. fever (S), headache (S), prostration (S), conjunctival inflammation (S), ... Section XI - Human Disease. In Nature. Significant Residual. Reported Death. Significant Subclinical. Significant ... Human Disease. Geographic Distribution. References. Remarks. References. History. Abbreviations. Information Exchange User ... Centers for Disease Control and Prevention. 1600 Clifton Rd. Atlanta, GA 30333, USA. 800-CDC-INFO (800-232-4636). Contact CDC- ...
Ocular tumors including melanomas of the eye, choroidal hemangiomas, conjunctival tumors, benign eye disease, and other eye ...
Histoplasmosis is an infectious disease caused by inhaling the spores of a fungus called Histoplasma capsulatum. This disease ... conjunctival Newcastle infection, psittacosis, and dermatophytosis) are of concern to poultry workers. Non-zootic infectious ... Of thses diseases, histoplasmosis may be the one most likely to cause serious illness in a poultry worker. ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
Eye Diseases [C11]. *Conjunctival Diseases [C11.187]. *Conjunctivitis [C11.187.183]. *Conjunctivitis, Allergic [C11.187.183.200 ...
  • The Schirmer I test, tear breakup time (TBUT), corneal and conjunctiva fluorescent staining , and conjunctival impression cytology tests were performed to both groups. (bvsalud.org)
  • Between October 2014 and June 2017, at the National Institute of Neoplastic Diseases (INEN) from Peru, 39 patients with squamous cell carcinoma of ocular conjunctiva, T1-T3, resected, were selected to receive adjuvant treatment. (ecancer.org)
  • The bulbar conjunctiva is where this disease most frequently presents itself, and it may have a poor prognosis if it is not diagnosed and treated early. (ecancer.org)
  • Diseases involving the CONJUNCTIVA . (bvsalud.org)
  • Conjunctival melanoma (ConjMel) is an adult ocular melanoma arising from conjunctiva , the visible ocular extern mucosa covering not only the anterior part of the eyeball, but also the internal surface of the eyelids . (share4rare.org)
  • This type of melanoma mostly arises from primary acquired melanocytosis (an acquire d pigmentation of the conjunctiva present in ~2/3 of cases) or from a conjunctival nevus (~1/4 of cases). (share4rare.org)
  • To evaluate 18-fluoro-2-deoxyglucose (FDG) whole-body positron emission tomography/computed radiographic tomography (PET/CT) for lymph node and metastatic staging of patients with conjunctival melanoma. (bmj.com)
  • Fourteen patients with T3 (n = 13) and T4 (n = 1) conjunctival melanoma (as defined in Chapter 42 of the AJCC staging manual) were staged for metastatic disease with PET/CT imaging with fusion. (bmj.com)
  • PET/CT images were studied for the presence and distribution of metastatic conjunctival melanoma (determined by standardised uptake values) and later confirmed by biopsy. (bmj.com)
  • Fourteen patients with conjunctival melanoma underwent PET/CT imaging. (bmj.com)
  • Only one patient with conjunctival melanoma (7.1%) was found to have metastatic disease on PET/CT imaging. (bmj.com)
  • Dr. Manuel Rodrigues is an oncology researcher at the Institut Curie (Paris, France) and in a recent interview he spoke to us about a quite rare ocular melanoma: conjunctival melanoma. (share4rare.org)
  • Are you affected by conjunctival melanoma? (share4rare.org)
  • How did you get interested in conjunctival melanoma in particular? (share4rare.org)
  • You are just working on a publication about conjunctival melanoma, so what are the latest learnings patients should be aware about? (share4rare.org)
  • Ocular oncology: advances in retinoblastoma, uveal melanoma and conjunctival melanoma. (paperbase.net)
  • Extremely Invasive Conjunctival Melanoma. (paperbase.net)
  • In addition to spreading by lymphatics and the bloodstream, conjunctival melanoma can undergo direct extension to the eyeball and orbit. (medscape.com)
  • reported an isolated gastric metastasis from a conjunctival melanoma. (medscape.com)
  • Theoretically, conjunctival melanoma may originate from primary acquired melanosis, preexisting nevi, or de novo lesions (without any histologic or clinical evidence of a preexisting lesion). (medscape.com)
  • Approximately 50% to 75% of cases of conjunctival melanoma arise in a setting of primary acquired melanosis. (medscape.com)
  • Evidence indicates that approximately 20% to 25% of patients with conjunctival melanoma have a history or microscopic evidence of a benign conjunctival nevus. (medscape.com)
  • There have been particularly substantial changes to the classification of conjunctival neoplasia and melanoma, based on the latest information from genetic and molecular studies. (who.int)
  • Kawasaki disease - Fever lasting more than 5 days with oral mucosal changes, conjunctival injection, and cervical lymphadenopathy. (logicalimages.com)
  • We describe a conjunctival exposure to WNV that occurred in the field and probably resulted in infection in the exposed person. (cdc.gov)
  • Of approximately forty zoonotic diseases of agricultural importance, six (Mycobacterium avium infection, erysipeloid, listerosis, conjunctival Newcastle infection, psittacosis, and dermatophytosis) are of concern to poultry workers. (cdc.gov)
  • Infectious diseases include diagnosis codes indicating an infection of the eye or ocular adnexa. (cdc.gov)
  • An infection of the eyes characterized by the presence in conjunctival epithelial cells of inclusion bodies indistinguishable from those of trachoma. (jefferson.edu)
  • Injury, infection, genetic diseases and malnutrition can affect the functioning of the Cornea. (perfectsightcentre.com)
  • The cornea becomes cloudy or warped due to disease, injury or infection. (perfectsightcentre.com)
  • Co-infection by more than one pathogen can change the expected transmission rates and virulence of disease whilst also promoting parasite infection. (lionalert.org)
  • However, post-mortem studies of mortalities among exotic felids in zoos indicate that among many viral diseases at least, there are parallel consequences of infection. (lionalert.org)
  • Following his tour as an EIS officer he joined the Division of Preparedness and Emerging Infection in CDC's National Center for Emerging and Zoonotic Infectious Disease. (cdc.gov)
  • Patients and Methods: Eleven patients with ocular prostheses participated in an assessment of clinical infection and the collection of conjunctival secretion. (bvsalud.org)
  • 1 Other congenital abnormalities of the aortic valve, degenerative calcific aortic stenosis, aortic insufficiency secondary to connective tissue disorders, and rheumatic aortic valve disease, are also predisposing lesions for infection. (mhmedical.com)
  • Corneal lesions show a tendency for the central pupillary area distribution with mild or absent conjunctival inflammation and no association to systemic disease. (cdc.gov)
  • This image reveals a close view of a patient's left eye with the upper lid retracted in order to reveal the inflamed conjunctival membrane lining the inside of both the upper and lower lids, due to what was determined to be a case of inclusion conjunctivitis, a type of conjunctival inflammation caused by the bacterium, Chlamydia trachomatis. (medscape.com)
  • The most commonly reported adverse events included conjunctival hemorrhage, eye pain, floaters, increased eye pressure and inflammation of the eye. (pharmaceuticalprocessingworld.com)
  • Use of conjunctival material for grafting over areas of the eye denuded by removal of a pterygium, pseudopterygium or symblepharon gives better results cosmetically, and in some instances functionally, than either thin split skin or mucous membrane from the mouth. (nih.gov)
  • Evicel versus Tisseel versus Sutures for Attaching Conjunctival Autograft in Pterygium Surgery: A Prospective Comparative Clinical Study. (paperbase.net)
  • Shtein RM, Sugar A. Pterygium and conjunctival degenerations. (medlineplus.gov)
  • This book comprises of four sections which include 26 chapters following as etiopathogenesis of pterygium, workup of a case of pterygium, pterygium excision with conjunctival autografting using glue, pterygium excision with conjunctival autograft (suture technique), conjunctival excision and extended tenectomy with conjunctival autograft for primary pterygium, pterygium surgery with autograft affixation using blood, antimetabolites in pterygium management, adjunctive therapy in pterygium management, management of corneal opacity after pterygium surgery etc. (ophthbooks.com)
  • Conjunctival squamous cell neoplasia associated with ocular cicatricial pemphigoid. (bmj.com)
  • Conjunctival squamous cell carcinoma is the second most frequent malignant ocular tumour [ 1 , 2 , 3 ]. (ecancer.org)
  • Newton et al [ 4 ] found that the rate of conjunctival squamous cell carcinoma decreases by approximately 49% for every 10% increase in latitude. (ecancer.org)
  • Malignant tumors are quite rare and the most represented is conjunctival squamous cell carcinoma . (bvsalud.org)
  • This book also gives the opportunity to learn techniques such as extensive tenectomy, narrow strip conjunctival autograft, sandwich technique, autologous blood, mini-flap technique and minor ipsilateral simple limbal epithelial transplantation (mini-SLET). (ophthbooks.com)
  • On the 5th day of illness, he developed lip redness, conjunctival injection, reddening of the BCG injection site, and edema of the hands and feet (Figure 3 ). (hindawi.com)
  • Photo showing lip redness and conjunctival injection. (hindawi.com)
  • CONCLUSIONS: The increase in BCFAs in the tears of blepharitis patients does not consistently participate in the conjunctival cell changes throughout the course of the disease. (bordeaux-neurocampus.fr)
  • Allergic eye disease: a clinical challenge. (bmj.com)
  • For these reasons, diseases such as allergic keratoconjunctivitis affecting the ocular surface primarily are common. (researchgate.net)
  • Nanotechnology for the treatment of allergic conjunctival diseases. (innovareacademics.in)
  • Vernal conjunctivitis comprises 0.5% of allergic eye diseases. (ijp-online.com)
  • The smaller sclerotomy (23G or smaller versus 20G) and usually the lack of scleral and conjunctival sutures reduce surgery time and postoperative discomfort [ 2 ]. (springer.com)
  • Alert the physician or suckle practitioner at the drop of a hat if any of these signs of progression to orbital cellulitis come off: conjunctival redness, difference in materialization, torture with orb move, perception muscle impotence or paralysis, or proptosis. (daubnet.com)
  • There are numerous conditions that may occur in the oral and maxillofacial region, ranging from developmental defects, injuries, and different pathologies including both benign and malignant diseases to the functional and esthetic aspects of the hard and soft tissues. (scirp.org)
  • Ocular tumors including melanomas of the eye, choroidal hemangiomas, conjunctival tumors, benign eye disease, and other eye tumors are treated at UCSF. (ucsf.edu)
  • Skin biopsy from the left groin confirmed the diagnosis of chronic familial benign pemphigus (Hailey-Hailey disease). (cdlib.org)
  • Chronic familial benign pemphigus, Hailey-Hailey disease (HHD), is a rare, autosomal dominant disorder with incomplete penetrance. (cdlib.org)
  • In managing these patients, palpating the regional lymph nodes is important because the spread to the conjunctival sac's ipsilateral preauricular, submandibular, and cervical nodes is well recognized. (medscape.com)
  • Patient B, a 42-year-old woman, was referred in October 2008 to the infectious disease department of Dijon University Hospital (Dijon, France) for intermittent fever (38.5°C) and swollen left-sided pretragal and cervical lymph nodes, which had evolved for 3 weeks despite administration of amoxicillin, followed by pristinamycin and prednisone, and ciprofloxacin for 7 days. (cdc.gov)
  • In ocular conjunctival carcinoma after surgery, adjuvant treatment has a role and kilovoltage surface brachytherapy opens a new door for the range of therapeutic options. (ecancer.org)
  • There were 80,388 notifications to the National Notifiable Diseases Surveillance System (NNDSS) between 1 October to 31 December 2017 (Table 2). (health.gov.au)
  • Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators. (harvard.edu)
  • Conjunctival Impression Cytology and Tear-Film Changes in Patients With Inflammatory Bowel Disease. (bvsalud.org)
  • To evaluate the ocular surface changes and tear - film functions in patients with inflammatory bowel disease (IBD). (bvsalud.org)
  • Design Retrospective cohort study evaluating overall and cancer mortality in relation to immunosuppressive drug exposure among patients with ocular inflammatory diseases. (bmj.com)
  • VEHSS identifies the annual prevalence of diagnosed Infectious and Inflammatory Diseases based on the presence of International Classification of Diseases (ICD)-9 and ICD-10 codes in patient claims or electronic health record (EHR) systems. (cdc.gov)
  • Diagnosed infectious and inflammatory diseases include a patient having one or more diagnosis codes indicating one or more of the subgroups listed below. (cdc.gov)
  • In a high percentage of cases, exophthalmos is associated with thyroid orbitopathy, an inflammatory disease related to hyperthyroidism. (imo.es)
  • The disease may be very serious, since the orbit is a non-extensible osseous cavity, in which an inflammatory process such as this can compress the optic nerve and cause blindness. (imo.es)
  • Other processes, which may cause exophthalmos, are orbital tumours, a large eyeball, high myopia or congenital glaucoma, as well as other thyroid or inflammatory orbital diseases. (imo.es)
  • The Department of Ophthalmology at UI Health provides comprehensive care for all types of eye conditions and diseases. (uillinois.edu)
  • Conjunctival tumors are common in tropical areas, where exposure to ultraviolet radiation is high and almost permanent. (bvsalud.org)
  • Conjunctival Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • 48 disease terms (MeSH) has been reported with IKZF1 gene. (cdc.gov)
  • The objective of this study was to determine the common early post-operative complications after oral and maxillofacial surgery in relation to the systemic condition, disease condition and demographic characteristic of the patient. (scirp.org)
  • Patients with DED most often include perimenopausal and postmenopausal women, the elderly, patients who have undergone refractive surgery, contact lens wearers, those exposed to environmental and occupational factors, those with disease state-related conditions (eg, autoimmune disease, diabetes mellitus, Parkinson's disease), and those on certain systemic and topical medications. (ajmc.com)
  • Patients with prior vitreoretinal surgery or impaired vision caused by additional eye disease in the study eye were excluded. (springer.com)
  • I deal primarily with diseases of the cornea and ocular surface, cataract surgery and refractive surgery (including LASIK). (perfectsightcentre.com)
  • More extensive services include state-of-the-art cataract surgery, femtosecond laser-assisted cataract surgery, premium intraocular lenses, and the management of common and complex eye diseases. (uillinois.edu)
  • Conjunctival melanomas may be associated with primary acquired melanosis (75%) or may arise from a preexisting nevus or de novo. (medscape.com)
  • Conjunctival nevus. (medscape.com)
  • [ 3 , 4 ] Lymphoproliferative disease of the orbit usually presents later in life and causes symptoms due to gradually increasing mass effect. (medscape.com)
  • Ocular inserts reduce symptoms resulting from moderate to severe dry eye disease. (medscape.com)
  • It is indicated for treatment of the signs and symptoms of dry eye disease in adults. (medscape.com)
  • This disease primarily affects a person's lungs, and its symptoms vary greatly. (cdc.gov)
  • Recent findings observed associations between depression and more severe dry eye disease symptoms and overall signs, suggesting patients with depression may be more likely to have a severe case of the disease. (hcplive.com)
  • Those who screened positive for depression had worse symptoms, more ocular discomfort, worse corneal staining scores, and worse composite severity scores of dry eye disease signs in comparison to participants who screened negative for depression. (hcplive.com)
  • Eligibility criteria included age ≥18 years, dry eye disease symptoms for ≥6 months, use of artificial tears at least twice a day for 2 weeks, and OSDI score of 25 - 80 at a screening visit and 21 - 80 at baseline. (hcplive.com)
  • Histoplasmosis is an infectious disease caused by inhaling the spores of a fungus called Histoplasma capsulatum. (cdc.gov)
  • Thought you might appreciate this item(s) I saw in The Pediatric Infectious Disease Journal. (lww.com)
  • Recent studies suggest a respiratory portal of entry of the suspected pathogen, although no infectious agent has been etiologically associated with the disease. (medscape.com)
  • Patient A, a 43-year-old woman, was referred in October 2006 to the infectious disease department of Auch Hospital (Auch, France). (cdc.gov)
  • Student, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine (LSHTM), London, improvement. (who.int)
  • Dr. Pillai is an internal medicine and infectious disease expert who joined the CDC as an Epidemic Intelligence Service Officer in 2011. (cdc.gov)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • The sutureless trans-conjunctival approach [ 1 ] has become the standard operating technique and replaced the conventional 20 gauge (G) PPV as the standard procedure in many centers. (springer.com)
  • Good afternoon, I'm Ashley Ghaffarzadeh and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communications Branch at the Centers for Disease Control and Prevention. (cdc.gov)
  • Image courtesy of Susan Lindsley, Centers for Disease Control and Prevention. (medscape.com)
  • Diagnosed or Treated Age-related macular degeneration (AMD) includes diagnosis codes specifying degenerative diseases of the macula, including macula drusen, dry-form AMD (including geographic atrophy), and wet-form AMD (including active choroidal neovascularization). (cdc.gov)
  • The authors reported no significant difference in the mean change between the treatment and placebo groups for OSDI score, conjunctival and corneal staining, TBUT and Schirmer's test. (reviewofoptometry.com)
  • Comparison of lateral orbital decompression with and without rim repositioning in thyroid eye disease. (paperbase.net)
  • Ocular irritation and reddening of the orbital and conjunctival tissues. (imo.es)
  • PET/CT imaging did not reveal any regional or systemic metastasis among 14 patients with advanced, diffuse and multifocal disease. (bmj.com)
  • Kawasaki disease (KD) is a self-limited, pediatric systemic vasculitis of unknown etiology. (lww.com)
  • There was no evidence of any associated systemic disorder or any other cutaneous disease, including Darier's disease. (cdlib.org)
  • Brief overview of Cornea and Ocular Surface Diseases I am Dr. Ashu Agarwal, Ophthamologist. (perfectsightcentre.com)
  • This page will give a brief overview of Cornea and Ocular Surface Diseases to the visitor. (perfectsightcentre.com)
  • Diseases of the cornea lead to loss of transparency, thus interfering with vision. (perfectsightcentre.com)
  • For many individuals, a corneal transplant may be the only hope for vision restoration, and may be necessary when the cornea is cloudy or damaged due to disease, injury, accident, malnutrition or hereditary conditions. (perfectsightcentre.com)
  • However, the success depends on a number of factors- recepient's eye condition and corneal disease, donor cornea quality and the surgical technique and skill. (perfectsightcentre.com)
  • Cornea specialists also work with the Contact Lens Service to offer advanced contact lens therapies, including the PROSE lens, and offer the opportunity to participate in the latest clinical trials for dry-eye diseases, corneal transplantation, and corneal infections. (uillinois.edu)
  • Topical cyclosporine 0.05% ophthalmic emulsion is effective FDA-approved treatment for dry eye disease. (medscape.com)
  • Lifitegrast ophthalmic solution is the first prescription specifically approved for dry eye disease by the FDA. (medscape.com)
  • While problems have rarely been noted in veterinary medicine, ophthalmic beta blockers should be used with caution in patients with bronchoconstrictive disease or congestive heart failure. (elephantcare.org)
  • Monkeypox causes a characteristic skin eruption and mucosal lesions and may cause ophthalmic disease. (ama-assn.org)
  • Monkeypox-related ophthalmic disease (MPXROD) includes a spectrum of ocular pathologies including eyelid/periorbital skin lesions, blepharoconjunctivitis, and keratitis). (ama-assn.org)
  • For treatment of dry eye disease (DED), or keratoconjunctivitis sicca (KCS), artificial tears are administered with and without preservatives, depending on severity. (medscape.com)
  • Doxycycline-associated conjunctival cysts. (harvard.edu)
  • Despite the widespread recognition of pyuria in acute Kawasaki disease (KD) patients and its inclusion in the American Heart Association list of supporting laboratory data for KD diagnosis, no systematic study of pyuria and the origin of these cells in KD patients have been reported. (lww.com)
  • Patients with DED often have a reduced quality of life (QoL) and experience psychological stress related to their disease. (ajmc.com)
  • This is how I got interested in these patients and their disease. (share4rare.org)
  • Share to help us reach patients with rare diseases all around the world! (share4rare.org)
  • Our physicians are known nationally for their clinical and research expertise and their ability to help patients with various complex corneal diseases. (uillinois.edu)
  • In addition, UI Health is the only Chicago-area provider to offer BostonSight PROSE treatment for patients with severely compromised ocular function as a result of complex corneal disease. (uillinois.edu)
  • We report the diagnosis of this disease in 2 patients in France by real-time PCR. (cdc.gov)
  • Two brothers had regional involvement of the posterior pole with disturbances of retinal function attributable to localized disease, and there was only mild progression in these patients. (elsevier.com)
  • It is estimated that 1 in 300 patients who have genital chlamydial disease develop adult inclusion conjunctivitis. (medscape.com)
  • Educate patients about the risks of sexually transmitted diseases and safe sexual practices. (medscape.com)
  • Some criticism was aimed toward the DREAM study's methodology based on its inclusion and/or exclusion criteria, as it allowed patients to continue their current dry eye regimen to mimic a "real-world" scenario and included those with moderate-to-severe disease. (reviewofoptometry.com)
  • Serum eye drops are used for severe dry eye disease with punctate epithelial defects and corneal damage to promote reepithelialization. (medscape.com)
  • Intercellular adhesion molecule-1 (ICAM-1) may be overexpressed in corneal and conjunctival tissues in dry eye disease. (medscape.com)
  • YNS is more frequently isolated but may be associated in rare cases with autoimmune diseases, other clinical manifestations implicating lymphatic functions or cancer and, hence, is also considered a paraneoplastic syndrome. (biomedcentral.com)
  • The study was a secondary analysis of data from the 12-month, multicenter Dry Eye Assessment and Management (DREAM) evaluating the efficacy of ω-3 fatty acid supplements in comparison to placebo utilizing the score of Ocular Surface Disease Index (OSDI) as the primary outcome. (hcplive.com)
  • This was the first multicenter, double-blind study comparing the efficacy of 3,000mg fish-derived oral omega-3 (EPA/DHA) daily supplementation for the treatment of moderate-to-severe dry eye disease (DED) vs. a placebo group containing refined olive oil. (reviewofoptometry.com)
  • Inclusion conjunctivitis is a less severe disease than trachoma and usually clears up spontaneously. (jefferson.edu)
  • We are reporting a case of Weil's disease which is a severe form of leptospirosis manifesting with fever, jaundice, renal failure and hemorrhagic manifestations as it is a very important public health problem and to focus that it is also occurring in our area. (jdrntruhs.org)
  • The initial evaluation in one patient demonstrated diffuse disease involving retinal pigment epithelium and choriocapillaris with severe widespread disturbance of retinal function. (elsevier.com)
  • AMD, a retinal disease causing severe and irreversible vision loss, is a major cause of blindness in individuals older than 55 years. (pharmaceuticalprocessingworld.com)
  • Leptospirosis is one of the most common zoonotic diseases, favored by a tropical climate and flooding during the monsoon, but occurring world-wide. (jdrntruhs.org)
  • Pars plana vitrectomy (PPV) is a standard procedure for the treatment of various vitreo-retinal diseases. (springer.com)
  • Our dedicated ophthalmologists and resident physicians provide a wide spectrum of care - ranging from managing common eye diseases and delivering routine eye exams to performing complex medical and surgical cases, including cataract, glaucoma, and retinal procedures. (uillinois.edu)
  • The chronic internal muscles and the retinal curvature when the eye are the lower conjunctival ffiuicjcs or viii. (lvmodernhomes.com)
  • Diagnosis codes are based on the International Classification of Diseases (ICD) system. (cdc.gov)
  • It is a syndrome - not a disease - that is associated with conditions as different as diseases implicating the lymphatic system, autoimmune diseases or cancers. (biomedcentral.com)
  • 1). Active trachoma affects an estimated 150 million people (2), and about 5.5 million are blind as a Trachoma is caused by the recurrent, chronic consequence of the disease. (who.int)
  • The bacteria normally colonise the mucosa of the upper respiratory tract without causing disease. (nsw.gov.au)
  • The Ocular Surface Disease Index scores of the IBD group (15.25±7.31) were significantly higher than the control group (11.75±7.33) (P=0.039). (bvsalud.org)
  • The purpose of this study is to review the recently published literature on ocular surface diseases treated with human autologous serum eye drops. (elsevier.com)
  • There is growing evidence indicating that the microbial communities that dwell on the human ocular surface are crucially important for ocular surface health and disease. (biomedcentral.com)
  • Although a healthy ocular surface can live in harmony with symbiotic microorganisms, microbial community imbalance or transient flora increases on the ocular surface may lead to diseases [ 3 ]. (biomedcentral.com)
  • DED is a multi-factorial disease of the ocular surface that responds best to a combination of pharmacologic and nonpharmacologic treatments. (ajmc.com)
  • Ocular disease is a byproduct of lid, conjunctival, and ocular surface deficits. (medscape.com)
  • Staphylococcal scalded skin syndrome (SSSS), or Ritter disease, is an acute disease caused by epidermolytic toxins released by strains of Staphylococcus aureus . (logicalimages.com)
  • 3] In 1885, Adolf Weil described the clinical hallmarks of this disease as an acute process characterized by splenomegaly, jaundice, and nephritis. (jdrntruhs.org)
  • The incidence of lymphoproliferative ocular diseases, especially malignant lymphoma, has increased over the years. (medscape.com)