Genital Diseases, Male
Genital Diseases, Female
Tumor Virus Infections
New therapies and prevention strategies for genital herpes. (1/404)Genital herpes is among the most prevalent sexually transmitted diseases. Optimal management of genital herpes includes accurate diagnosis, antiviral therapy, and counseling of patients about complications and transmission of herpes simplex virus (HSV). Antiviral therapy offers significant palliation, and the option of episodic or suppressive treatment should be offered to all patients with genital herpes. Valacyclovir and famciclovir are two newer antiviral agents that are effective and safe for the treatment of genital herpes. Prevention strategies for sexual and perinatal transmission of HSV have not been well defined. Availability of type-specific serological tests for HSV antibodies may assist in identifying persons at risk for acquiring or transmitting HSV infection. Further research is needed to define strategies to prevent the spread of this epidemic infection. (+info)
Genital warts and their treatment. (2/404)Genital warts are manifestations of a common viral sexually transmitted disease (STD) that are often diagnosed and treated with a variety of clinical specialties. Unlike for other STDs, there is a general lack of a well-established treatment algorithm for the management of external genital warts. This, coupled with a wide variety of treatments and clinical settings, makes the development of a simple algorithm virtually impossible. In this review what is known and not known about current treatments and case management will be discussed. (+info)
Risk factors for abnormal anal cytology in young heterosexual women. (3/404)Although anal cancers are up to four times more common in women than men, little is known about the natural history of anal human papillomavirus (HPV) infections and HPV-related anal lesions in women. This study reports on the prevalence of and risks for anal cytological abnormalities over a 1-year period in a cohort of young women participating in a study of the natural history of cervical HPV infection. In addition to their regularly scheduled sexual behavior interviews and cervical testing, consenting women received anal HPV DNA and cytological testing. Anal cytology smears were obtained from 410 women whose mean age was 22.5 +/- 2.5 years at the onset of the study. Sixteen women (3.9%) were found to have abnormal anal cytology: 4 women had low-grade squamous intraepithelial lesions (SILs) or condyloma; and 12 women had atypical cells of undetermined significance. Factors found to be significantly associated with abnormal anal cytology were a history of anal sex [odds ratio (OR), 6.90; 95% confidence interval (CI), 1.7-47.2], a history of cervical SILs (OR, 4.13; 95% CI, 1.3-14.9), and a current anal HPV infection (OR, 12.28; 95% CI, 3.9-43.5). The strong association between anal intercourse and the development of HPV-induced SILs supports the role of sexual transmission of HPV in anal SILs. Young women who had engaged in anal intercourse or had a history of cervical SILs were found to be at highest risk. (+info)
Tissue specific HPV expression and downregulation of local immune responses in condylomas from HIV seropositive individuals. (4/404)OBJECTIVE: To study the effect of tissue specific human papillomavirus (HPV) expression and its effect on local immunity in condylomas from HIV positive individuals. METHODS: Biopsy specimens of eight penile and eight perianal condylomas from HIV seropositive individuals were analysed. Expression of viral genes (HIV-tat and HPV E7 and L1) was determined by RT-PCR. The status of local immunity also was determined by RT-PCR by measuring CD4, CD8, CD16, CD1a, HLA-DR, and HLA-B7 mRNA levels in the tissues. Differentiation was determined by measuring involucrin, keratinocyte transglutaminase, as well as cytokeratins 10, 16, and 17. Proliferation markers such as PCNA and c-myc were also determined. RESULTS: The transcription pattern of HPV in perianal condylomas, which preferentially expressed the early (E7) gene, was different from that of penile condylomas, which primarily expressed the late (L1) gene. This transcription pattern is in good correlation with the keratinisation and differentiation patterns of the two epithelia: perianal biopsies preferentially expressed K16 and K17 while penile warts mainly expressed K10, markers of parakeratotic and orthokeratotic epithelia, respectively. Perianal biopsies also showed a higher degree of proliferation (PCNA and c-myc). Interestingly, transcription of HIV-tat was also higher in perianal than in penile biopsies. A high degree of local immunodeficiency was observed in perianal biopsies--that is, levels of CD4, CD16, and CD1a mRNAs were significantly lower. A negative correlation between CD1a (Langerhans cells) levels and HPV E7 levels was established. HPV E7 levels positively correlated with HIV-tat levels. Perianal tissues demonstrated more CD1a depression and tat associated HPV upregulation. CONCLUSION: HIV influences the expression of HPV genes resulting in local immunosuppression that might lead to an inappropriate immune surveillance of viral infection. Also, tissue type is an important factor in controlling viral transcription in a differentiation dependent manner. These findings may explain the higher rate of dysplasia and neoplasia in the perianal area. (+info)
Overriding of cyclin-dependent kinase inhibitors by high and low risk human papillomavirus types: evidence for an in vivo role in cervical lesions. (5/404)High risk types of human papillomavirus (HPV) are agents in the aetiology of cervical carcinoma. The products of two early genes, E6 and E7, appear to be the principal transforming proteins. Studies of various monolayer cell culture systems have shown that the E7 oncoprotein of human papillomavirus type 16 is able to neutralize or bypass the inhibitory effect of the cell cycle-dependent kinase (CDK) inhibitors (CKIs) p21WAF1/CIP1 and p27KIP1. To understand whether the p21WAF1/CIP1 or p27KIP1 neutralization also plays a role in vivo, we performed studies on clinical specimens. Forty-five cervical biopsies, including HPV-negative mucosa, HPV 16-positive preinvasive (low and high grade lesions) and invasive neoplasia as well as HPV 6-positive condyloma acuminatum were analysed by single and double immunohistology. We examined the positive cell cycle regulator cyclin A and the universal cell cycle marker Ki67 as well as the negative cell cycle regulators p21WAF1/CIP1 and p27KIP1. Here, we show that in a significant fraction of cells the G1 block can be overcome despite high levels of CKIs in HPV lesions. This phenomenon, which was more evident for p21WAF1/CIP1 than for p27KIP1 was most marked in low grade lesions and in condylomata acuminata, in which a high viral productivity is expected. These results indicate that the overriding of CKI inactivation by viral oncoproteins appears to be a conserved property between low and high risk HPV types. We conclude that the CKI neutralization by HPVs is likely to be required for viral DNA replication rather than for malignant transformation of the host cell. (+info)
The cost effectiveness of patient-applied versus provider-administered intervention strategies for the treatment of external genital warts. (6/404)OBJECTIVE: External genital warts are one of the fastest growing sexually transmitted diseases in the United States today. Two forms of therapy are available: provider-administered and patient-applied. In the most widely used provider-administered ablative therapies, sustained clearance rates range from 18.5% to 40.1%. With nonablative, patient-applied therapies, which are typically more acceptable to patients, sustained clearance rates range from 19.6% with podofilox gel to 44.0% with imiquimod cream. The purpose of this study, given the range of therapies available, their cost differences, and clinical trial-reported differences in rates of sustained clearance, is to determine which therapy modalities, from the providers' perspective, are the most cost effective and which are likely to be the most acceptable to the patient population. STUDY DESIGN: We consider the cost effectiveness of the two patient-applied therapies as first-line therapy followed by provider-administered ablative treatment as second-line therapy. A decision-analytic model framework is developed, with data drawn both from clinical trials and from previously published studies. RESULTS: When considering a two-stage therapy model, with an average sustained clearance rate of 30% assumed for provider-administered ablative therapies, estimated costs per sustained cleared patient are $1265 for patients initially treated with imiquimod and $1304 for patients initially treated with podofilox gel. CONCLUSIONS: Initial treatment with imiquimod is the preferred intervention option as it yields a 39% greater sustained clearance rate than podofilox gel while being 3% less costly per successful outcome. (+info)
Detection of human papillomavirus types 6 and 11 in pubic and perianal hair from patients with genital warts. (7/404)Genital human papillomavirus (HPV) types 6 and 11 are of clinical importance due to their role in the development of anogenital warts. A pilot study was performed to investigate whether DNAs from HPV types 6 and 11 are present in hairs plucked from the pubic and perianal regions and eyebrows of patients with genital warts at present and patients with a recent history of genital warts. Genital HPV DNA was detected in 9 of 25 (36%) pubic hair samples and in 11 of 22 (50%) perianal hair samples by the CPI/CPIIg PCR. After sequencing of 17 of 20 samples, HPV type 6 or 11 was detected in 6 of 25 (24%) hair samples from the pubis and 8 of 22 (36%) hair samples from the perianal region. These types were not detected in plucked eyebrow hairs. In contrast, the HPV types associated with epidermodysplasia verruciformis were detected in similar proportions (62%) in both samples of pubic and eyebrow hairs. Moreover, HPV type 6 and 11 DNAs were detected in pubic hairs plucked from two patients who had been successfully treated and who did not show any lesion at the time of hair collection; this finding is an argument that HPV DNA may persist in this region. The presence of genital HPV types in plucked pubic and perianal hair suggests that there is an endogenous reservoir for HPV which may play a role in the recurrences of genital warts. (+info)
Nucleotide sequence and characterization of human papillomavirus type 83, a novel genital papillomavirus. (8/404)Studies of human papillomaviruses (HPV) are hampered by the lack of a conventional culture system, because HPV completes its life cycle only in fully differentiated human tissue. To overcome this obstacle, the athymic mouse xenograft system has been used to study the pathogenesis of a limited number of HPV types. We recently reported the propagation of a novel HPV type in the mouse xenograft system and the cloning of its genome. Consensus primer PCR had previously identified this virus as MM7, LVX82, or PAP291. Here we report the nucleotide sequence of the 8104-bp genome of this virus, now called HPV 83. HPV 83 is most closely related to HPV 61 and HPV 72, placing it in the papillomavirus genome homology group A3. Based on limited epidemiological data, the histological appearance of infected human foreskin implants, and the structure of the predicted HPV 83 E7 protein, this virus is probably of at least intermediate cancer risk. Like other papillomaviruses, HPV 83 produces an E1 E4, E5 transcript, but the position of the splice acceptor differs from that of other HPVs. The presence of an E5 open reading frame in the HPV 83 genome is uncertain; the most likely candidate to be the HPV 83 E5 protein has some structural similarity to the bovine papillomavirus 1 E5 oncoprotein, and is unlike most other HPV E5 proteins. HPV 83 is a relatively prevalent genital papillomavirus that has the largest genome of any characterized HPV and several other novel structural features that merit further study. (+info)
Condylomata acuminata, also known as genital warts or venereal warts, are a type of sexually transmitted infection (STI) caused by the human papillomavirus (HPV). They are small, flesh-colored or pink growths that appear on the genital area, anus, or mouth of infected individuals. Condylomata acuminata are highly contagious and can be spread through sexual contact, including vaginal, anal, and oral sex. They are more common in women than men and are often asymptomatic, meaning that infected individuals may not experience any symptoms. However, they can cause discomfort, itching, and bleeding. Treatment for condylomata acuminata typically involves the use of topical creams or ointments, cryotherapy (freezing), or surgical removal. It is important to note that while treatment can remove the visible warts, it does not cure the underlying HPV infection, which can persist and potentially lead to more serious health problems, such as cervical cancer. Therefore, regular screening and vaccination against HPV are important for preventing the spread and long-term consequences of this STI.
Podophyllin is a medication that is used to treat warts, particularly plantar warts (warts on the sole of the foot) and verrucae vulgaris (warts on the hands and feet). It is a strong chemical that works by destroying the cells of the wart, causing it to fall off. Podophyllin is usually applied to the affected area using a cotton swab or applicator. The medication can cause skin irritation and redness, and it is important to follow the instructions carefully to minimize these side effects. It is also important to avoid contact with the medication on healthy skin, as it can cause burns. Podophyllin is not suitable for everyone, and it is important to consult a healthcare professional before using it. They can determine if it is the right treatment for your specific type of wart and advise you on how to use it safely and effectively.
Genital neoplasms, male refer to tumors or abnormal growths that develop in the male reproductive system, including the testes, epididymis, prostate gland, seminal vesicles, and penis. These neoplasms can be benign (non-cancerous) or malignant (cancerous) and can cause a range of symptoms, including pain, swelling, difficulty urinating, and changes in sexual function. Treatment options for genital neoplasms depend on the type, size, location, and stage of the tumor, as well as the patient's overall health and preferences. Some common treatments for genital neoplasms include surgery, radiation therapy, chemotherapy, and hormone therapy. Early detection and treatment are important for improving outcomes and reducing the risk of complications.
Genital diseases in males refer to medical conditions that affect the male reproductive system, including the testes, prostate gland, penis, and related structures. These conditions can be acute or chronic, and can range from minor infections to more serious conditions that can affect fertility and overall health. Some common examples of genital diseases in males include sexually transmitted infections (STIs) such as chlamydia, gonorrhea, and syphilis, as well as non-infectious conditions such as erectile dysfunction, prostate cancer, and varicocele (swelling of the veins in the scrotum). Diagnosis of genital diseases in males typically involves a physical examination, medical history, and laboratory tests such as blood tests, urine tests, and imaging studies. Treatment options depend on the specific condition and may include medications, surgery, or other interventions. It is important for males to seek medical attention if they experience any symptoms of a genital disease, as prompt diagnosis and treatment can help prevent complications and improve outcomes.
Anus Neoplasms refer to abnormal growths or tumors that develop in or around the anus. These growths can be either benign or malignant, and they can occur in various parts of the anal canal, including the rectum, anal verge, and anal sphincter. Benign anal neoplasms are non-cancerous growths that do not spread to other parts of the body. Examples of benign anal neoplasms include hemorrhoids, anal polyps, and skin tags. Malignant anal neoplasms, on the other hand, are cancerous growths that can spread to other parts of the body if left untreated. The most common type of malignant anal neoplasm is anal cancer, which is usually caused by the human papillomavirus (HPV) infection. Symptoms of anal neoplasms may include rectal bleeding, pain or discomfort during bowel movements, itching or discharge from the anus, and a lump or mass in the anal area. Diagnosis of anal neoplasms typically involves a physical examination, biopsy, and imaging tests such as colonoscopy or MRI. Treatment for anal neoplasms depends on the type, size, and location of the growth, as well as the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Early detection and treatment of anal neoplasms are crucial for improving the chances of a successful outcome.
Urethral neoplasms refer to abnormal growths or tumors that develop in the urethra, which is the tube that carries urine from the bladder to the outside of the body. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) in nature. Benign urethral neoplasms include urethral polyps, fibromas, and adenomas, which are usually small and do not spread to other parts of the body. Malignant urethral neoplasms, on the other hand, are more serious and can include squamous cell carcinoma, transitional cell carcinoma, and adenocarcinoma. Symptoms of urethral neoplasms may include difficulty urinating, blood in the urine, frequent urination, pain or burning during urination, and discomfort in the genital area. Diagnosis typically involves a physical examination, urine analysis, and imaging tests such as cystoscopy or biopsy. Treatment for urethral neoplasms depends on the type, size, and location of the tumor, as well as the overall health of the patient. Options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Early detection and treatment are important for improving outcomes and reducing the risk of complications.
Anus diseases refer to medical conditions that affect the anus, which is the opening at the end of the rectum through which solid and liquid waste is eliminated from the body. Some common examples of anus diseases include: 1. Hemorrhoids: Swollen veins in the anus or rectum that can cause pain, itching, and bleeding. 2. Anal fissures: Tears in the lining of the anus that can cause pain, bleeding, and difficulty passing stool. 3. Anal cancer: A rare but serious cancer that can develop in the cells lining the anus. 4. Fistulas: Abnormal connections between the anus and other organs, such as the bladder or vagina. 5. Anal abscess: A collection of pus that forms in the skin or tissue around the anus. 6. Perianal warts: Small, raised growths on the skin around the anus that are caused by a sexually transmitted infection. 7. Anal itching: A persistent or severe itching sensation around the anus that can be caused by a variety of factors, including skin conditions, infections, and allergies. These conditions can be treated with a variety of methods, including medications, lifestyle changes, and surgery, depending on the severity and underlying cause of the condition. It is important to seek medical attention if you experience any symptoms related to anus diseases, as early diagnosis and treatment can help prevent complications and improve outcomes.
Penile diseases refer to medical conditions that affect the structure or function of the penis. These conditions can range from minor to severe and can affect both the physical and sexual health of a person. Some common penile diseases include: 1. Erectile dysfunction: A condition where a person is unable to achieve or maintain an erection sufficient for sexual activity. 2. Peyronie's disease: A condition where the penis becomes curved due to the formation of scar tissue. 3. Phimosis: A condition where the foreskin of the penis is too tight to be retracted over the glans (head) of the penis. 4. Balanitis: An inflammation of the glans or foreskin of the penis. 5. Chlamydia: A sexually transmitted infection (STI) that can cause inflammation of the urethra, prostate, and other reproductive organs. 6. Gonorrhea: Another STI that can cause inflammation of the urethra, prostate, and other reproductive organs. 7. Herpes: A viral infection that can cause sores or blisters on the penis. 8. Cancer: Rarely, penile cancer can occur, which can be treated with surgery, radiation therapy, or chemotherapy. It is important to note that penile diseases can have a significant impact on a person's quality of life and should be treated promptly by a healthcare professional.
Urogenital neoplasms refer to tumors or abnormal growths that develop in the urinary and genital systems of the body. These neoplasms can occur in various parts of the urinary system, including the kidneys, ureters, bladder, and urethra, as well as in the genital system, including the prostate, testicles, ovaries, and uterus. Urogenital neoplasms can be either benign or malignant. Benign neoplasms are non-cancerous and do not spread to other parts of the body, while malignant neoplasms, also known as cancers, are cancerous and can invade nearby tissues and spread to other parts of the body through the bloodstream or lymphatic system. Some common types of urogenital neoplasms include kidney cancer, bladder cancer, prostate cancer, testicular cancer, ovarian cancer, and uterine cancer. The symptoms of urogenital neoplasms can vary depending on the location and type of the tumor, but may include pain, blood in the urine or stool, difficulty urinating, and changes in bowel or bladder habits. Treatment options for urogenital neoplasms may include surgery, radiation therapy, chemotherapy, and targeted therapy, depending on the stage and type of the tumor.
Penile neoplasms refer to abnormal growths or tumors that develop on the penis. These growths can be benign (non-cancerous) or malignant (cancerous). Benign penile neoplasms include conditions such as fibromas, papillomas, and granulomas, while malignant neoplasms include penile cancer. Penile cancer is a relatively rare type of cancer, but it can be aggressive and difficult to treat if not detected early. Treatment options for penile neoplasms depend on the type, size, and location of the growth, as well as the overall health of the patient.
Genital neoplasms, female refer to tumors or abnormal growths that develop in the female reproductive system, including the ovaries, uterus, cervix, vagina, and vulva. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and can present with a variety of symptoms, including abnormal vaginal bleeding, pain, and swelling. Treatment options for genital neoplasms depend on the type, size, and location of the tumor, as well as the patient's overall health and age. Early detection and treatment are important for improving outcomes and reducing the risk of complications.
Vulvar neoplasms refer to abnormal growths or tumors that develop on the vulva, which is the external female genitalia. These growths can be benign (non-cancerous) or malignant (cancerous). Vulvar neoplasms can occur at any age, but are more common in older women. Some common types of vulvar neoplasms include vulvar intraepithelial neoplasia (VIN), which is a precancerous condition that can progress to vulvar cancer if left untreated, and vulvar squamous cell carcinoma (VSCC), which is a type of cancer that develops in the cells that line the vulva. Symptoms of vulvar neoplasms may include itching, burning, pain, bleeding, or the appearance of a lump or mass on the vulva. Diagnosis typically involves a physical examination, biopsy, and imaging studies such as ultrasound or MRI. Treatment for vulvar neoplasms depends on the type, size, and location of the growth, as well as the patient's overall health. Options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Early detection and treatment are important for improving outcomes and reducing the risk of complications.
Genital diseases in females refer to any medical conditions that affect the female reproductive system, including the vagina, cervix, uterus, fallopian tubes, ovaries, and vulva. These diseases can be caused by a variety of factors, including infections, hormonal imbalances, genetics, and lifestyle choices. Some common genital diseases in females include: 1. Vulvovaginitis: Inflammation of the vulva and vagina, often caused by a bacterial, yeast, or viral infection. 2. Cervicitis: Inflammation of the cervix, which can be caused by sexually transmitted infections (STIs) or other factors. 3. Endometriosis: A condition in which tissue that normally lines the inside of the uterus grows outside of it, causing pain and other symptoms. 4. Ovarian cysts: Fluid-filled sacs that develop on the ovaries, which can cause pain and other symptoms. 5. Pelvic inflammatory disease (PID): An infection of the reproductive organs that can cause pain, fever, and other symptoms. 6. Polycystic ovary syndrome (PCOS): A hormonal disorder that can cause irregular periods, weight gain, and other symptoms. 7. Vulvar cancer: A rare but serious cancer that affects the vulva. Treatment for genital diseases in females depends on the specific condition and its severity. It may include medications, surgery, or other therapies. It is important for women to see a healthcare provider regularly for check-ups and to discuss any concerns about their reproductive health.
Cutaneous syphilis is a type of syphilis that affects the skin and mucous membranes. It is caused by the bacterium Treponema pallidum and is transmitted through sexual contact or from mother to child during pregnancy or childbirth. There are three stages of cutaneous syphilis: primary, secondary, and latent. In the primary stage, a single or multiple small, painless sores called chancres may appear on the genital area, mouth, anus, or other areas of the body. In the secondary stage, a rash of flat, red, or brown spots may develop on the skin and mucous membranes, accompanied by fever, swollen lymph nodes, and other symptoms. In the latent stage, there may be no symptoms, but the infection can still be transmitted to others. Cutaneous syphilis can be diagnosed through a physical examination, blood tests, or a skin biopsy. Treatment typically involves antibiotics, such as penicillin, which can cure the infection and prevent further complications.，，、。
Warts are a common skin condition caused by a virus called human papillomavirus (HPV). They are small, rough growths that appear on the skin and can be either raised or flat. Warts can occur on any part of the body, but they are most common on the hands, feet, and face. There are several types of warts, including common warts, plantar warts, genital warts, and flat warts. Common warts are the most common type and typically appear on the hands and fingers. Plantar warts are found on the sole of the foot and can be painful to walk on. Genital warts are found in the genital area and can be sexually transmitted. Flat warts are small, flat growths that can appear anywhere on the body. Warts are generally harmless and can be treated with various methods, including topical creams, cryotherapy, and surgical removal. However, some types of warts, such as genital warts, can be more difficult to treat and may require more aggressive treatment options. It is important to see a healthcare provider if you have warts, especially if they are causing discomfort or if you are concerned about their appearance.
A cicatrix, hypertrophic is a scar that has thickened and become raised above the surrounding skin due to an excessive healing response. It is typically caused by an injury or surgery that damages the dermis, the middle layer of the skin, and triggers the production of excess collagen fibers. Cicatrices can be unsightly and may cause discomfort or pain, but they are usually not a cause for concern from a medical standpoint. However, in some cases, a hypertrophic cicatrix may require treatment to reduce its size or improve its appearance. This can be done through various methods, such as corticosteroid injections, silicone gel sheets, or laser therapy.
Tumor virus infections refer to the presence of viruses that can cause cancer in infected individuals. These viruses are also known as oncoviruses or tumor-inducing viruses. They can infect various types of cells in the body and alter their normal functioning, leading to the development of tumors. There are several types of tumor viruses, including human papillomavirus (HPV), hepatitis B and C viruses (HBV and HCV), Epstein-Barr virus (EBV), and Kaposi's sarcoma-associated herpesvirus (KSHV). These viruses can cause various types of cancers, such as cervical cancer, liver cancer, nasopharyngeal cancer, and Kaposi's sarcoma, respectively. Tumor virus infections can be transmitted through various means, including sexual contact, blood transfusions, and mother-to-child transmission. Diagnosis of tumor virus infections typically involves the detection of viral antigens or antibodies in the blood or other bodily fluids. Treatment for tumor virus infections depends on the type of virus and the stage of cancer. In some cases, antiviral medications may be used to control the virus and prevent further spread. In other cases, surgery, radiation therapy, or chemotherapy may be necessary to treat the cancer. Vaccines are also available for some tumor viruses, such as HPV, to prevent infection and reduce the risk of cancer.
Vaginal neoplasms refer to abnormal growths or tumors that develop in the vaginal tissue. These growths can be benign (non-cancerous) or malignant (cancerous). Vaginal neoplasms can occur in any part of the vagina, including the vestibule, the cervix, the corpus, and the vagina itself. Some common types of vaginal neoplasms include vaginal polyps, vaginal cysts, vaginal leiomyomas (fibroids), vaginal adenosis (abnormal growth of glandular tissue), vaginal intraepithelial neoplasia (VIN), and vaginal cancer. VIN is a precancerous condition that can progress to invasive vaginal cancer if left untreated. Vaginal cancer is a rare but serious condition that can be treated with surgery, radiation therapy, chemotherapy, or a combination of these treatments. It is important for women to be aware of the signs and symptoms of vaginal neoplasms, such as abnormal vaginal bleeding, pain during intercourse, and changes in vaginal discharge, and to seek medical attention if they experience any of these symptoms. Early detection and treatment of vaginal neoplasms can improve outcomes and increase the chances of successful treatment.
Giant condyloma acuminatum
List of skin conditions
Index of oncology articles
List of MeSH codes (C02)
List of MeSH codes (C17)
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- Condylomata acuminata are benign anogenital warts most often caused by HPV types 6 and 11, as are laryngeal and oropharyngeal warts. (msdmanuals.com)
- The surgeon had treated several patients with anogenital condylomata acuminata using the Nd:YAG laser. (cdc.gov)
- the incidence of anogenital condyloma acuminata in children shows remarkable increase in the last two decades, as well as by its association with sexual abuse. (bvsalud.org)
- Genital warts, also known as condylomata acuminata or venereal warts, are a sexually transmitted infection (STI) caused by the human papillomavirus (HPV). (vumc.org)
- Also referred to as venereal warts or condylomata acuminata, genital warts are a sexually transmitted disease that a person contracts through sexual contact. (richmonddermatologist.com)
- Regardless of the mode of therapy chosen, recurrence rates are high for any patient with condylomata acuminata. (medscape.com)
- Veregen ® is a topical ointment indicated for the treatment of external genital and perianal warts (Condylomata acuminata) in immunocompetent patients 18 years and older (1.1) . (nih.gov)
- Polyphenon® E is the active agent of an ointment approved for the topical treatment of external genital and perianal warts (Condylomata acuminata) in immunocompetent patients over 18 years of age. (dermago-group.com)
- To determine which treatment modalities for condylomata acuminata are associated with the lowest direct medical costs. (nih.gov)
- Estimated direct medical costs per complete clearance associated with different treatment options for condylomata acuminata. (nih.gov)
- Surgical modalities, including excision, electrodesiccation, loop electrosurgical excision procedure, and laser, as well as podofilox are low-cost options for the treatment of condylomata acuminata. (nih.gov)