Computational Biology
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
Algorithms
Systems Biology
Sociology
Software
Physiological Phenomena
Sequence Analysis, Protein
Computer Simulation
Proteins
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Biology
Artificial Intelligence
Databases, Factual
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
Sequence Alignment
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Systems Integration
Models, Biological
Pattern Recognition, Automated
Markov Chains
Databases, Protein
Internet
User-Computer Interface
Sequence Analysis, DNA
Computer Graphics
Models, Statistical
Cluster Analysis
A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.
Information Storage and Retrieval
Gene Regulatory Networks
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
Gene Expression Profiling
Models, Genetic
Models, Molecular
Bayes Theorem
A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result.
Molecular Biology
Developmental Biology
Models, Theoretical
Oligonucleotide Array Sequence Analysis
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Amino Acid Sequence
Genome, Human
Synthetic Biology
Protein Conformation
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
Evolution, Molecular
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Protein Structure, Tertiary
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Transcription Factors
Ringo, Doty, Demeter and Simard, Cerebral Cortex 1994;4:331-343: a proof of the need for the spatial clustering of interneuronal connections to enhance cortical computation. (1/20328)
It has been argued that an important principle driving the organization of the cerebral cortex towards local processing has been the need to decrease time lost to interneuronal conduction delay. In this paper, I show for a simplified model of the cerebral cortex, using analytical means, that if interneuronal conduction time increases proportional to interneuronal distance, then the only way to increase the numbers of synaptic events occurring in a fixed finite time period is to spatially cluster interneuronal connections. (+info)The Genexpress IMAGE knowledge base of the human brain transcriptome: a prototype integrated resource for functional and computational genomics. (2/20328)
Expression profiles of 5058 human gene transcripts represented by an array of 7451 clones from the first IMAGE Consortium cDNA library from infant brain have been collected by semiquantitative hybridization of the array with complex probes derived by reverse transcription of mRNA from brain and five other human tissues. Twenty-one percent of the clones corresponded to transcripts that could be classified in general categories of low, moderate, or high abundance. These expression profiles were integrated with cDNA clone and sequence clustering and gene mapping information from an upgraded version of the Genexpress Index. For seven gene transcripts found to be transcribed preferentially or specifically in brain, the expression profiles were confirmed by Northern blot analyses of mRNA from eight adult and four fetal tissues, and 15 distinct regions of brain. In four instances, further documentation of the sites of expression was obtained by in situ hybridization of rat-brain tissue sections. A systematic effort was undertaken to further integrate available cytogenetic, genetic, physical, and genic map informations through radiation-hybrid mapping to provide a unique validated map location for each of these genes in relation to the disease map. The resulting Genexpress IMAGE Knowledge Base is illustrated by five examples presented in the printed article with additional data available on a dedicated Web site at the address http://idefix.upr420.vjf.cnrs.fr/EXPR++ +/ welcome.html. (+info)Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae. (3/20328)
Introns have typically been discovered in an ad hoc fashion: introns are found as a gene is characterized for other reasons. As complete eukaryotic genome sequences become available, better methods for predicting RNA processing signals in raw sequence will be necessary in order to discover genes and predict their expression. Here we present a catalog of 228 yeast introns, arrived at through a combination of bioinformatic and molecular analysis. Introns annotated in the Saccharomyces Genome Database (SGD) were evaluated, questionable introns were removed after failing a test for splicing in vivo, and known introns absent from the SGD annotation were added. A novel branchpoint sequence, AAUUAAC, was identified within an annotated intron that lacks a six-of-seven match to the highly conserved branchpoint consensus UACUAAC. Analysis of the database corroborates many conclusions about pre-mRNA substrate requirements for splicing derived from experimental studies, but indicates that splicing in yeast may not be as rigidly determined by splice-site conservation as had previously been thought. Using this database and a molecular technique that directly displays the lariat intron products of spliced transcripts (intron display), we suggest that the current set of 228 introns is still not complete, and that additional intron-containing genes remain to be discovered in yeast. The database can be accessed at http://www.cse.ucsc.edu/research/compbi o/yeast_introns.html. (+info)Bayesian inference on biopolymer models. (4/20328)
MOTIVATION: Most existing bioinformatics methods are limited to making point estimates of one variable, e.g. the optimal alignment, with fixed input values for all other variables, e.g. gap penalties and scoring matrices. While the requirement to specify parameters remains one of the more vexing issues in bioinformatics, it is a reflection of a larger issue: the need to broaden the view on statistical inference in bioinformatics. RESULTS: The assignment of probabilities for all possible values of all unknown variables in a problem in the form of a posterior distribution is the goal of Bayesian inference. Here we show how this goal can be achieved for most bioinformatics methods that use dynamic programming. Specifically, a tutorial style description of a Bayesian inference procedure for segmentation of a sequence based on the heterogeneity in its composition is given. In addition, full Bayesian inference algorithms for sequence alignment are described. AVAILABILITY: Software and a set of transparencies for a tutorial describing these ideas are available at http://www.wadsworth.org/res&res/bioinfo/ (+info)DNA sequence chromatogram browsing using JAVA and CORBA. (5/20328)
DNA sequence chromatograms (traces) are the primary data source for all large-scale genomic and expressed sequence tags (ESTs) sequencing projects. Access to the sequencing trace assists many later analyses, for example contig assembly and polymorphism detection, but obtaining and using traces is problematic. Traces are not collected and published centrally, they are much larger than the base calls derived from them, and viewing them requires the interactivity of a local graphical client with local data. To provide efficient global access to DNA traces, we developed a client/server system based on flexible Java components integrated into other applications including an applet for use in a WWW browser and a stand-alone trace viewer. Client/server interaction is facilitated by CORBA middleware which provides a well-defined interface, a naming service, and location independence. [The software is packaged as a Jar file available from the following URL: http://www.ebi.ac.uk/jparsons. Links to working examples of the trace viewers can be found at http://corba.ebi.ac.uk/EST. All the Washington University mouse EST traces are available for browsing at the same URL.] (+info)Detecting selective expression of genes and proteins. (6/20328)
Selective expression of a gene product (mRNA or protein) is a pattern in which the expression is markedly high, or markedly low, in one particular tissue compared with its level in other tissues or sources. We present a computational method for the identification of such patterns. The method combines assessments of the reliability of expression quantitation with a statistical test of expression distribution patterns. The method is applicable to small studies or to data mining of abundance data from expression databases, whether mRNA or protein. Though the method was developed originally for gene-expression analyses, the computational method is, in fact, rather general. It is well suited for the identification of exceptional values in many sorts of intensity data, even noisy data, for which assessments of confidences in the sources of the intensities are available. Moreover, the method is indifferent as to whether the intensities are experimentally or computationally derived. We show details of the general method and examples of computational results on gene abundance data. (+info)Protein subcellular location prediction. (7/20328)
The function of a protein is closely correlated with its subcellular location. With the rapid increase in new protein sequences entering into data banks, we are confronted with a challenge: is it possible to utilize a bioinformatic approach to help expedite the determination of protein subcellular locations? To explore this problem, proteins were classified, according to their subcellular locations, into the following 12 groups: (1) chloroplast, (2) cytoplasm, (3) cytoskeleton, (4) endoplasmic reticulum, (5) extracell, (6) Golgi apparatus, (7) lysosome, (8) mitochondria, (9) nucleus, (10) peroxisome, (11) plasma membrane and (12) vacuole. Based on the classification scheme that has covered almost all the organelles and subcellular compartments in an animal or plant cell, a covariant discriminant algorithm was proposed to predict the subcellular location of a query protein according to its amino acid composition. Results obtained through self-consistency, jackknife and independent dataset tests indicated that the rates of correct prediction by the current algorithm are significantly higher than those by the existing methods. It is anticipated that the classification scheme and concept and also the prediction algorithm can expedite the functionality determination of new proteins, which can also be of use in the prioritization of genes and proteins identified by genomic efforts as potential molecular targets for drug design. (+info)A two-dimensional model of brightness perception based on spatial filtering consistent with retinal processing. (8/20328)
We have applied a multiple scale, 2-D model of brightness perception to a broad range of brightness phenomena. The filters encapsulate only processing that is well established to occur in retinal ganglion cells. Their outputs are then combined in the simplest way compatible with the earliest levels of cortical processing. Not only essential features of a number of the phenomena but also more subtle shading effects are reproduced. Because of the retinal nature of this model, these results would appear to support previous speculation that much of the ground work for brightness perception is performed at the retinal level. (+info)
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Histone
"PLOS Computational Biology. 13 (1): e1005365. Bibcode:2017PLSCB..13E5365B. doi:10.1371/journal.pcbi.1005365. PMC 5305278. PMID ... Journal of Computational Biology. 13 (1): 102-12. doi:10.1089/cmb.2006.13.102. PMID 16472024.. ... "Molecular and Cellular Biology. 22 (5): 1298-306. doi:10.1128/MCB.22.5.1298-1306.2002. PMC 134702. PMID 11839797.. ... "Molecular and Cellular Biology. 23 (5): 1590-601. doi:10.1128/MCB.23.5.1590-1601.2003. PMC 151715. PMID 12588979.. ...
Epistasis
It was originally a concept from genetics but is now used in biochemistry, computational biology and evolutionary biology. It ... "PLoS Computational Biology. 7 (12): e1002302. arXiv:1108.3590. Bibcode:2011PLSCB...7E2302L. doi:10.1371/journal.pcbi.1002302. ... "Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. BCB '14. New York, NY, ... Computational prediction[edit]. Numerous computational methods have been developed for the detection and characterization of ...
David Eisenberg
ISCB (International Society for Computational Biology) Senior Scientist Award (2013). References[edit]. *^ Fogg, C. N.; Kovats ... "PLoS Computational Biology. 9 (6): e1003116. doi:10.1371/journal.pcbi.1003116. PMC 3681620 .. ... Member, National Academy of Sciences (1989; Biophysics & Computational Biology section). *Pierce Award of the Immunotoxin ... Eisenberg's current research focuses on the structural biology of amyloidogenic proteins, while his computational efforts ...
Dual inheritance theory
PLOS Computational Biology. 5 (8): e1000491. doi:10.1371/journal.pcbi.1000491. ISSN 1553-7358. PMC 2722739 . PMID 19714206. ... Culture is part of human biology: Why the superorganic concept serves the human sciences badly. In M. Goodman and A. S. Moffat( ... Culture is Part of Human Biology: Why the Superorganic Concept Serves the Human Sciences Badly. In Science Studies: Probing the ... Cultural drift is a process roughly analogous to genetic drift in evolutionary biology. In cultural drift, the frequency of ...
Aminoacyl tRNA synthetase
PLoS Computational Biology. 14 (4): e1006101. doi:10.1371/journal.pcbi.1006101. PMID 29659563.. ... "Microbiology and Molecular Biology Reviews. 64 (1): 202-36. doi:10.1128/MMBR.64.1.202-236.2000. PMC 98992. PMID 10704480.. ... Delarue, M (1995). "Aminoacyl-tRNA synthetases". Structural Biology. 5: 48-55.. *^ "Molecule of the Month: Aminoacyl-tRNA ... Molecular Cell Biology. 11 (9): 668-74. doi:10.1038/nrm2956. PMC 3042954. PMID 20700144.. ...
NMDA receptor
"PLOS Computational Biology. 11 (12): e1004559. Bibcode:2015PLSCB..11E4559B. doi:10.1371/journal.pcbi.1004559. PMC 4670163. PMID ... "In Van Dongen AM (ed.). Biology of the NMDA Receptor. Boca Raton, Florida: CRC Press. ISBN 978-1-4200-4414-0. . PMID 21204415. ... "The chemical biology of clinically tolerated NMDA receptor antagonists". Journal of Neurochemistry. 97 (6): 1611-1626. doi ...
Mark Miodownik
"PLoS Computational Biology. 4 (3): e1000030. Bibcode:2008PLSCB...4E0030B. doi:10.1371/journal.pcbi.1000030. PMC 2274883. PMID ... Physical Biology. 6 (1): 016010. Bibcode:2009PhBio...6a6010C. doi:10.1088/1478-3975/6/1/016010. PMID 19342769.. ...
Allosteric regulation
"PLOS Computational Biology. 7 (9): e1002148. doi:10.1371/journal.pcbi.1002148. ISSN 1553-7358. PMC 3174156 . PMID 21935347.. ... "Advances in Protein Chemistry and Structural Biology. Advances in Protein Chemistry and Structural Biology. 83: 163-221. doi: ... Nature Structural Biology. 10 (1): 59-69. doi:10.1038/nsb881. ISSN 1072-8368. PMID 12483203.. ...
Synaptic weight
"PLOS Computational Biology. 9 (10): e1003248. Bibcode:2013PLSCB...9E3248I. doi:10.1371/journal.pcbi.1003248. PMC 3808453. PMID ... In a computational neural network, a vector or set of inputs x. {\displaystyle {\textbf {x}}}. and outputs y. {\displaystyle {\ ... Biology[edit]. For biological networks, the effect of synaptic weights is not as simple as for linear neurons or Hebbian ... corresponding in biology to the amount of influence the firing of one neuron has on another. The term is typically used in ...
Peregrine falcon
"PLOS Computational Biology. 14 (4): e1006044. Bibcode:2018PLSCB..14E6044M. doi:10.1371/journal.pcbi.1006044. PMC 5896925. PMID ... "Journal of Experimental Biology. 223 (Pt 1): jeb209031. doi:10.1242/jeb.209031. PMID 31822552. S2CID 209313631. Retrieved 6 ... Blondel, J.; Aronson, J. (1999). Biology and Wildlife of the Mediterranean Region. Oxford University Press. p. 136. ISBN 978-0- ... Brown, L. (1976). Birds of Prey: Their biology and ecology. Hamlyn. p. 226. ISBN 978-0-600-31306-9. .. ...
Menopause
"PLOS Computational Biology. 9 (6): e1003092. Bibcode:2013PLSCB...9E3092M. doi:10.1371/journal.pcbi.1003092. PMC 3681637. PMID ... a b Lock, M. & Nguyen, V. (2010) An Anthropology of Biomedicine, Chapter 4 "Local Biologies and Human Difference" (pp. 84-89), ... "Biology of Reproduction. 79 (3): 398-406. doi:10.1095/biolreprod.108.068536. PMC 2553520. PMID 18495681.. ... "Current Biology. 25 (6): 746-750. doi:10.1016/j.cub.2015.01.037. PMID 25754636. S2CID 3488959.. ...
Eugene Koonin
From 1985-1991, Koonin worked as a research scientist in computational biology in the Institutes of Poliomyelitis and ... "Are There Laws of Genome Evolution?". PLOS Computational Biology. 7 (8): e1002173. doi:10.1371/journal.pcbi.1002173. Koonin, E ... Koonin gained a Master of Science in 1978 and a PhD in 1983 in molecular biology, both from the Department of Biology at Moscow ... He is a recognised expert in the field of evolutionary and computational biology. ...
Multiple sequence alignment
"PLOS Computational Biology. 3 (8): e123. doi:10.1371/journal.pcbi.0030123. PMC 1963500. PMID 17784778.. ... "European Molecular Biology Laboratory. 2007. Retrieved March 7, 2010.. *^ Castresana J (April 2000). "Selection of conserved ... Expressed with the big O notation commonly used to measure computational complexity, a naïve MSA takes O(LengthNseqs) time to ... Dynamic programming and computational complexity[edit]. A direct method for producing an MSA uses the dynamic programming ...
Herd immunity
"PLoS Computational Biology. 5 (2): e1000280. doi:10.1371/journal.pcbi.1000280. PMC 2625434. PMID 19197342.. ...
Sequence homology
"PLoS Computational Biology. 6 (3): e1000703. doi:10.1371/journal.pcbi.1000703. PMC 2845645. PMID 20361041.. ... "PLoS Computational Biology. 11 (7): e1004394. doi:10.1371/journal.pcbi.1004394. PMC 4504502. PMID 26181593.. ... "PLoS Computational Biology. 7 (6): e1002073. doi:10.1371/journal.pcbi.1002073. PMC 3111532. PMID 21695233.. ... "PLoS Computational Biology. 10 (7): e1003754. doi:10.1371/journal.pcbi.1003754. PMC 4117431. PMID 25080083.. ...
HIV/AIDS research
"PLOS Computational Biology. 11 (4): e1004179. arXiv:1503.08992. Bibcode:2015PLSCB..11E4179Z. doi:10.1371/journal.pcbi.1004179. ...
Promoter (genetics)
"PLoS Computational Biology. 3 (4): e72. Bibcode:2007PLSCB...3...72Y. doi:10.1371/journal.pcbi.0030072. PMC 1853124. PMID ... BMC Systems Biology. 5: S2. doi:10.1186/1752-0509-5-S1-S2.. ...
Enzyme promiscuity
"PLoS Computational Biology. 2 (6): e69. Bibcode:2006PLSCB...2...69W. doi:10.1371/journal.pcbi.0020069. PMC 1480538 . PMID ... "Molecular Biology and Evolution. 24 (12): 2716-22. doi:10.1093/molbev/msm204. PMC 2678898 . PMID 17884825.. ... "BMC Evolutionary Biology. 7 Suppl 2: S3. doi:10.1186/1471-2148-7-S2-S3. PMC 1963480 . PMID 17767731.. ... "PLoS Biology. 10 (12): e1001446. doi:10.1371/journal.pbio.1001446. PMC 3519909 . PMID 23239941.. ...
RNA splicing
"PLoS Computational Biology. 6 (11): e1001016. Bibcode:2010PLSCB...6E1016C. doi:10.1371/journal.pcbi.1001016. PMC 2991248. PMID ... "PLOS Computational Biology. 9 (11): e1003314. Bibcode:2013PLSCB...9E3314E. doi:10.1371/journal.pcbi.1003314. PMC 3820534. PMID ... "Nature Structural & Molecular Biology. 19 (7): 719-21. doi:10.1038/nsmb.2327. PMC 3465671. PMID 22705790.. ... "Molecular Biology of the Cell". 2012 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. 2013.. ...
Microbiota
"PLoS Computational Biology. 6 (2): e1000667. Bibcode:2010PLSCB...6E0667W. doi:10.1371/journal.pcbi.1000667. PMC 2829047 . PMID ... Current Biology. 18 (13): R567-9. doi:10.1016/j.cub.2008.05.024.. ... Current Opinion in Plant Biology. 4 (4): 343-350. doi:10.1016/S1369-5266(00)00183-7. PMID 11418345.. ... This combinatorial approach enables a systems-level understanding of microbial contributions to human biology.[27] But also ...
Tensegrity
"PLoS Computational Biology. 8 (5): e1002509. Bibcode:2012PLSCB...8E2509E. doi:10.1371/journal.pcbi.1002509. PMC 3349725. PMID ... Biology[edit]. Biotensegrity, a term coined by Dr. Stephen Levin, is the application of tensegrity principles to biologic ... Series in Mathematical Biology and Medicine. 3. doi:10.1142/2755. ISBN 978-981-02-2268-0. .. ... A theory of tensegrity in molecular biology to explain cellular structure has been developed by Harvard physician and scientist ...
rDock
"PLoS Computational Biology. 10 (4): e1003571. Bibcode:2014PLSCB..10E3571R. doi:10.1371/journal.pcbi.1003571. PMC 3983074. PMID ...
Erdős-Bacon number
"PLoS Computational Biology. 4 (5): e1000058. doi:10.1371/journal.pcbi.1000058. PMC 2275312 . PMID 18404205.. ... "PLoS Computational Biology. 1 (5): e50. doi:10.1371/journal.pcbi.0010050. PMC 1274291 . PMID 16261192.. ... "Current Biology. 21 (8): 677-80. doi:10.1016/j.cub.2011.03.017. PMC 3092984 . PMID 21474316.. ... "Discrete & Computational Geometry. 4 (1): 287-290. doi:10.1007/BF02187731. Retrieved 28 January 2016.. ...
Default mode network
"PLoS Computational Biology. 5 (5): e1000381. doi:10.1371/journal.pcbi.1000381. PMC 2671306. PMID 19412534.. ...
Ribosomal protein
"PLoS Computational Biology. 2 (2): e10. doi:10.1371/journal.pcbi.0020010. PMC 1364506 . PMID 16485038.. ... "Journal of Molecular Biology. 425 (4): 767-79. doi:10.1016/j.jmb.2012.11.040. PMC 3568210 . PMID 23228329.. ... "Current Opinion in Structural Biology. 24: 165-9. doi:10.1016/j.sbi.2014.01.002. PMC 4358319 . PMID 24524803.. ... Methods in Molecular Biology. 1279. pp. 219-33. doi:10.1007/978-1-4939-2398-4_14. ISBN 978-1-4939-2397-7. PMID 25636622.. ...
Storage (memory)
"PLoS Computational Biology. 11 (11): e1004592. doi:10.1371/journal.pcbi.1004592.. *^ a b Moore, T. (n.d.). Rehearsal. Retrieved ... Gallistel, C.R.; King (2009). Memory and the computational brain: why cognitive science will transform neuroscience. Wiley- ... computational searches for similarity against millions of traces that would be present in memory matrix to calculate similarity ... remains as one of the most influential computational models of memory. The model uses both short-term memory, termed short-term ...
Granger causality
"PLoS Computational Biology. 7 (3): e1001110. Bibcode:2011PLSCB...7E1110K. doi:10.1371/journal.pcbi.1001110. PMC 3063721. PMID ... it remains a popular method for causality analysis in time series due to its computational simplicity.[4][5] The original ...
Protein subcellular localization prediction
Computational Molecular Biology. 4 (1): 1-17. doi:10.5376/cmb.2014.04.0001.. ... Journal of Molecular Biology. 283 (4): 707-25. doi:10.1006/jmbi.1998.2144. PMID 9790834.. ... computational tools can now provide fast and accurate localization predictions for many organisms. This has resulted in ... "Assessing the precision of high-throughput computational and laboratory approaches for the genome-wide identification of ...
Talk:WormBase
Computational BiologyWikipedia:WikiProject Computational BiologyTemplate:WikiProject Computational BiologyComputational Biology ... This article is within the scope of WikiProject Computational Biology, a collaborative effort to improve the coverage of ... WikiProject Computational Biology. (Rated Start-class, Mid-importance). ... Computational Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the ...
Circadian clock
"PLoS Computational Biology. 3 (4): e68. Bibcode:2007PLSCB...3...68B. doi:10.1371/journal.pcbi.0030068. PMC 1851983. PMID ... Systems biology approaches to elucidate oscillating mechanisms[edit]. Modern experimental approaches using systems biology have ... Loudon AS (Jul 2012). "Circadian biology: a 2.5 billion year old clock". Current Biology. 22 (14): R570-1. doi:10.1016/j.cub. ... "PLoS Biology. 8 (6): e1000394. doi:10.1371/journal.pbio.1000394. PMC 2885980. PMID 20563306.. ...
Computational neuroscience
arXiv:q-bio/0512013. Bibcode:2006Natur.440.1007S. doi:10.1038/nature04701. PMC 1785327. PMID 16625187.. ... Computational clinical neuroscience[edit]. Computational Clinical Neuroscience is a field that brings together experts in ... In theory, computational neuroscience would be a sub-field of theoretical neuroscience which employs computational simulations ... Annual Computational Neuroscience Meeting (CNS)- a yearly computational neuroscience meeting.. *Neural Information Processing ...
Alternative medicine
Note that as used here, "biology" does not refer to the science of biology, but is a usage newly coined by NCCIH in the primary ... They quoted one of these scientists, Steven Salzberg, a genome researcher and computational biologist at the University of ... is that part of medical science that applies principles of biology, physiology, molecular biology, biophysics, and other ... "Biology-based" as coined by NCCIH may refer to chemicals from a nonbiological source, such as use of the poison lead in ...
QIAGEN Silicon Valley
... and is purchased by QIAGEN in May of the same year Systems biology Bioinformatics Computational genomics Computational biology ... The software has been cited in thousands of scientific molecular biology publications and is one of several tools for systems ... "Best of Show: Life Science Software & Informatics". Bio-IT World. June 13, 2007. Retrieved April 7, 2012. "Ingenuity Systems ... "Stanford University Licenses IPA, Collaborates on Systems Biology Solutions" (Press release). Ingenuity Systems. November 3, ...
Positron emission tomography
Computational Imaging VIII. 7533: 75330R. Bibcode:2010SPIE.7533E..0RH. CiteSeerX 10.1.1.175.3054. doi:10.1117/12.850771.. ... "Magnetic Resonance Materials in Physics, Biology and Medicine. 26 (1): 99-113. doi:10.1007/s10334-012-0353-4. ISSN 0968-5243. ... Qi, J.; R. Leahy (2006). "Iterative reconstruction techniques in emission computed tomography". Physics in Medicine and Biology ... PET and SPECT are capable of detecting areas of molecular biology detail (even prior to anatomic change). PET scanning does ...
Leaf
"PLoS Computational Biology. 4 (4): e1000055. arXiv:0705.0902. Bibcode:2008PLSCB...4E0055L. doi:10.1371/journal.pcbi.1000055. ... "School of Biology, Georgia Institute of Technology. Retrieved 12 March 2017.. *. Geneve, Robert. "Leaf" (PDF). PLS 220: ... "Basic Biology. Adam Purcell. Retrieved 17 February 2017.. *. Simpson, Michael G. "Plants of San Diego County, California". ... Journal of Theoretical Biology. 259 (3): 440-448. doi:10.1016/j.jtbi.2009.05.002. PMID 19446571.. ...
Octopus
"The Journal of Experimental Biology. 198: 1717-1727. PMID 9319626.. *^ a b Wells, J. (1996). "Cutaneous respiration in Octopus ... "Frontiers in Computational Neuroscience. doi:10.3389/fncom.2013.00060. PMC 3662989 . PMID 23745113.. ... Department of Biology, University of Victoria (Canada), 101 pp.. *^ Norman, M. 2000. Cephalopods: A World Guide. ConchBooks, ... "Journal of Experimental Biology. 209: 3697-3707. doi:10.1242/jeb.02435. PMID 16985187. Retrieved 4 February 2014.. ...
EA-3167
Cilj je bio da se razvije neletalno onesposobljavajuće sredstvo. EA-3167 je imao identično dejstvo kao i QNB, ali je bio ... Annual Reports in Computational Chemistry 4: 217-241. doi:10.1016/S1574-1400(08)00012-1. ... EA-3167 nije bio razvijen u oružje, niti proizvođen u velikim količinama. ...
Computer graphics (computer science)
Computational mathematics. *Computational physics. *Computational chemistry. *Computational biology. *Computational social ... It focuses on the mathematical and computational foundations of image generation and processing rather than purely aesthetic ... Computer graphics studies the manipulation of visual and geometric information using computational techniques. ...
Reptile
"Biology Letters. 8 (1): 104-107. doi:10.1098/rsbl.2011.0477. PMC 3259949. PMID 21775315.. CS1 maint: uses authors parameter ( ... a computational analysis". Canadian Journal of Zoology. 81 (8): 1346-1357. doi:10.1139/z03-122.. ... Biology Letters. 6 (4): 544-547. doi:10.1098/rsbl.2009.1024. PMC 2936204. PMID 20106856.. CS1 maint: multiple names: authors ... Goannas: The Biology of Varanid Lizards. University of New South Wales Press. ISBN 978-0-86840-456-1, p. 43. ...
List of inorganic compounds
Chemical biology. *Clinical chemistry. *Fullerene chemistry. *Medicinal chemistry. *Molecular biology. *Neurochemistry. * ...
Chemical engineering
Engineering the Future of Biology and Biotechnology, Rice University, archived from the original on 2010-07-25, retrieved 2011- ... Chemical engineering is a branch of engineering that uses principles of chemistry, physics, mathematics, biology, and economics ... Computational fluid dynamics. *Corrosion engineering. *Cost estimation. *Electrochemistry. *Electrochemical engineering. * ...
Mineralogy
Biomineralogy is a cross-over field between mineralogy, paleontology and biology. It is the study of how plants and animals ... More recently, driven by advances in experimental technique (such as neutron diffraction) and available computational power, ...
Field Museum of Natural History
"CEB, Committee on Evolutionary Biology, University of Chicago, Faculty (Field Museum)".. *^ "University of Illinois at Chicago ... "A Computational Analysis of Limb and Body Dimensions in Tyrannosaurus rex with Implications for Locomotion, Ontogeny, and ... Since its founding the Field Museum has been an international leader in evolutionary biology and paleontology, and archaeology ... environmental and evolutionary biology, anthropology, botany, geology, archaeology, museology and related subjects.[citation ...
Swarm intelligence
"Frontiers in Computational Neuroscience. 9 (90). doi:10.3389/fncom.2015.00090.. *^ a b al-Rifaie, MM; Bishop, J.M.; Caines, S ... Agent-based model in biology. *Bait ball. *Collective animal behavior. *Feeding frenzy ... "Computational Intelligence. 4: 10-19. doi:10.1109/MCI.2009.933096.. *^ du Castel, Bertrand (15 July 2015). "Pattern Activation/ ... The "computational creativity" of the above-mentioned systems are discussed in[40][44][45] through the two prerequisites of ...
Bioinformática, a enciclopedia libre
Michael S. Waterman (1995). Introduction to Computational Biology: Sequences, Maps and Genomes (en inglés). CRC Press. ISBN 0- ... redirixe ao termo Bioinformatics a definición de Computational biology. *↑ Un exemplo da utilización como sinónimos de ... Foundations of Computational and Systems Biology MIT Course. *Bioinformatics software resources. Gilbert, D. Briefings in ... Pevzner, Pavel A. (2000). Computational Molecular Biology: An Algorithmic Approach (en inglés). The MIT Press. ISBN 0-262-16197 ...
Wikipedia:WikiProject Molecular Biology/Computational Biology/ISCB competition announcement 2015
Wikipedia:WikiProject Molecular Biology , Computational Biology (Redirected from Wikipedia:WikiProject Computational Biology/ ... Articles should be chosen in the area of computational biology. The Computational Biology WikiProject have selected over 1,200 ... A list of articles within scope of Computational Biology ordered by quality is available via Category:Computational Biology ... Relatedness to Computational biology will be assumed as demonstrated *for Wikidata items *if they link to a page on the English ...
Materials science
Efforts surrounding Integrated computational materials engineering are now focusing on combining computational methods with ... Wide range, e.g., claytronics, synthetic biology Quantum dots Research, experiments, prototypes[26]. LCD, LED Quantum dot laser ... Nanoscale structure in biology is often called ultrastructure. Materials which atoms and molecules form constituents in the ... Computational materials science and engineeringEdit. With continuing increases in computing power, simulating the behavior of ...
Economics
"Agent-Based Computational Economics: Growing Economies from the Bottom Up" (PDF). Artificial Life. 8 (1): 55-82. CiteSeerX ... and evolutionary biology.[94] ... See Agent-based computational economics *^ Interest payments ...
Theodore Holmes Bullock
One reason for his move to UCSD was that he hoped to bridge the gap between Marine Biology and medicine. ... studies on nerve nets lead him to be one of the first experimentalists to understand the value and importance of computational ... During this time he also studied marine biology and other courses at the Pomona College Marine Biological Laboratory. He ... Bullock was a respected teacher who taught many courses while at UCLA, such as zoology and advanced invertebrate biology. He ...
Ron McClamrock
Existential Cognition: Computational Minds in the World. University of Chicago Press. 1995. ... However, unlike the continental philosophers, McClamrock relies upon results from modern information sciences, biology and ... His position is that the methodological individualism inherent in many contemporary forms of computational theories of the mind ...
Tyrannosaurus - Simple English Wikipedia, the free encyclopedia
Hutchinson J.R. et al (2011). "A computational analysis of limb and body dimensions in Tyrannosaurus rex with implications for ... Research is done on its biology, life history and biomechanics. The feeding habits, physiology and potential speed of ... "Historical Biology: A Journal of Paleobiology 16 (1): 1-12. doi:10.1080/0891296021000050755. http://www.ingentaconnect.com/ ...
Archaea
Madigan MT; Martino JM (2006). Brock Biology of Microorganisms (11th ed.). Pearson. p. 136. ISBN 0-13-196893-9.. ... "A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, ... Garrett RA; Klenk H (2005). Archaea: Evolution, Physiology and Molecular Biology. WileyBlackwell. ISBN 1-4051-4404-1.. ... Biology defines a species as a group of related organisms. The familiar exclusive breeding criterion (organisms that can breed ...
Cold Spring Harbor Laboratory
Cell biology and genomics. RNA interference (RNAi) and small-RNA biology; DNA replication; RNA splicing; signal transduction; ... computational genomics; cloud computing and Big Data. ... doctoral students in biology, teachers of biology in the K-12 ... Horace Freedland Judson, The Eighth Day of Creation: The Makers of the Revolution in Biology (Simon & Schuster, 1979), esp. pp ... "Plant Biology - Cold Spring Harbor Laboratory". Cold Spring Harbor Laboratory. Retrieved 2018-08-08.. ...
Mind-wandering
"PLOS Biology. 3 (5): e141. doi:10.1371/journal.pbio.0030141. PMC 1074751. PMID 15819609.. ... In addition to neural models, computational models of consciousness based on Bernard Baars' Global Workspace theory[32][page ...
Arqueas, a enciclopedia libre
2008). Archaea: New Models for Prokaryotic Biology (en inglés). Caister Academic Press. ISBN 978-1-904455-27-1.. ... "A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, ... Garrett, RA; Klenk, H (2005). Archaea: Evolution, Physiology and Molecular Biology (en inglés). WileyBlackwell. ISBN 1-4051- ... Martinko, JM; Madigan, MT (2005). Brock Biology of Microorganisms (en inglés) (11th ed.). Englewood Cliffs, N.J: Prentice Hall ...
ವಂಶವಾಹಿ - ವಿಕಿಪೀಡಿಯ
PLOS Computational Biology 8 (5): e1002514. doi:10.1371/journal.pcbi.1002514. PMID 22615551. ... Patterson, C (November 1988). "Homology in classical and molecular biology.". Molecular Biology and Evolution 5 (6): 603-25. ... A molecular biology textbook available free online through NCBI Bookshelf. *↑ Slack, J.M.W. Genes-A Very Short Introduction. ... Watson, JD, Baker TA, Bell SP, Gann A, Levine M, Losick R. (2004). "Ch9-10", Molecular Biology of the Gene, 5th ed., Peason ...
Doksazosin
Marta 2000, ALLHAT studija je zaustavila svoja ispitivanja, jer je doksazosin bio manje efektivan od jednostavnih diuretika, i ... Annual Reports in Computational Chemistry 4: 217-241. doi:10.1016/S1574-1400(08)00012-1. ...
Antonio Damasio
"Current Biology. 21 (1): 1-5. doi:10.1016/j.cub.2010.11.042. PMC 3030206. PMID 21167712.. ... Current work on the biology of moral decisions, neuro-economics, social communication, and drug-addiction, has been strongly ... In it, Damasio suggested that the philosopher Baruch Spinoza's thinking foreshadowed discoveries in biology and neuroscience ... "Investigating the biology of consciousness". Philosophical Transactions of the Royal Society of London. Series B: Biological ...
Royal Society of New South Wales
Biology and paleobiology. 2009. Professor Archer is a distinguished biologist and palaeobiologist. He was one of the key ... Computational and theoretical quantum chemistry 2010 Professor Hush was one of Australia's most distinguished and ... Professor Warren is a distinguished pathologist whose research interests concerned tumour biology and thrombosis. ... internationally renowned chemists with outstanding achievements in computational and theoretical quantum chemistry. ...
Computational biology - Wikipedia
Some notable examples include Journal of Computational Biology and PLOS Computational Biology. The PLOS computational biology ... Computational evolutionary biology[edit]. Computational biology has assisted the field of evolutionary biology in many ... Cancer computational biology[edit]. Cancer computational biology is a field that aims to determine the future mutations in ... Computational pharmacology[edit]. Computational pharmacology (from a computational biology perspective) is "the study of the ...
Computational Biology | OHSU
Computational Biology The Computational Biology program leads in the development of innovative computational approaches at OHSU ... Welcome to Computational Biology. The OHSU computational biology program leads in the development of innovative computational ... The computational biology team has advanced training in machine learning, statistical techniques, and a track record of ... Research in the computational biology program focuses on integrative analysis of high dimensional heterogeneous molecular, ...
Computational Systems Biology
Dr Philip Lewis is an Honorary Reader in the Cell and Developmental Biology department at UCL. His work focuses on mathematical ... Understand the uses of modelling in biology with reference to examples drawn across the spectrum of bioscience research. ... Research in the field of Systems Biology is highly interdisciplinary. It often involves biologists working with colleagues from ... and computational approaches to biological research. He delivers the Dynamic Biological Systems module to UCL undergraduates ...
Computational Biology
... Research. We construct computational models to improve our knowledge of biomedical processes and ... Contact Computational Biology. Postbus 513 5600 MB Eindhoven T:. +31 (0)40 247 5537. F:. +31 (0)40 243 4970. E:. r.a.v.dijck. ... The research group Computational Biology contributes to the education of the Department of Biomedical Engineering ...
Computational and Predictive Biology | ORNL
Computational and Predictive Biology Analyzing biological systems using computational techniques. The pursuit of a holistic ... The Computational and Predictive Biology Group brings together and collaborates with scientists from related experimental, ... computational, and technical disciplines to build increasingly detailed computational models of biological systems. These ... Biological research is increasingly dependent on, and driven by, evolving computational analysis and prediction. ...
Mathematical & Computational Biology | Series | Springer
Computational Biology Endorsed by the International Society for Computational Biology, the Computational Biology series ... Mathematical & Computational Biology , Series. This selection contains titles in Mathematical & Computational Biology ... Theoretical Biology Iwasa, Y. (Ed) The "Theoretical Biology" series publishes volumes on all aspects of life sciences research ... Bernstein Series in Computational Neuroscience Benda, J. (Ed) Bernstein Series in Computational Neuroscience reflects the ...
Computational & Synthetic Biology | Computer Science & Engineering
Allen School faculty and students collaborate with researchers in biology and medicine on a wide range of computational ... Biology is fast becoming an information science, with large databases and sophisticated algorithms now essential tools in the ... A team led by professor Rajesh Rao published the results of a study that employs computational methods to explain human choices ... Seelig Lab for Synthetic Biology. Members of the Seelig Lab aim to advance our understanding of how biological organisms ...
Computational biology (eBook, 2010) [WorldCat.org]
Computational biology. [David Fenyo;] -- Computational biology is an interdisciplinary field that applies mathematical, ... biology_methods> # Computational Biology--methods a schema:Intangible ;. schema:name "Computational Biology--methods"@en ;. . ... In Computational Biology, expert practitioners present a broad survey of computational biology methods by focusing on their ... In Computational Biology, expert practitioners present a broad survey of computational biology methods by focusing on their ...
Computational Methods in Systems Biology | SpringerLink
This book constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology ... Computational Methods in Systems Biology. 6th International Conference CMSB 2008, Rostock, Germany, October 12-15, 2008. ... This book constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology ... On a Continuous Degree of Satisfaction of Temporal Logic Formulae with Applications to Systems Biology ...
Computational Molecular Biology | The MIT Press
This book explains the algorithmic foundations and computational approaches underlying areas of structural biology including ... and computational biology. They can carry out such tasks as predicting a natural language sentence, or segmenting an image into ... Over the past decade, novel algorithms have been developed both for analyzing biological data and for synthetic biology ... Becoming conversant with the intricacies of molecular biology and its extensive technical vocabulary can be a challenge, though ...
Computational Molecular Biology | The MIT Press
Computational Molecular Biology Computational molecular biology brings together computational, statistical, experimental, and ... Learning and Inference in Computational Systems Biology Neil D. Lawrence, Mark Girolami, Magnus Rattray, and Guido Sanguinetti ... Current Topics in Computational Molecular Biology Tao Jiang, Ying Xu, and Michael Q. Zhang 2002. ... Kernel Methods in Computational Biology Bernhard Schölkopf, Koji Tsuda, and Jean-Philippe Vert 2004. ...
CMU SCS - Computational Molecular Biology Research
Computational Molecular Biology in the School of Computer Science Computational molecular biology is an active area of research ... Degree in Biological Sciences/Computational Biology, the Professional Masters Program in Computational Biology, and the Merck ... Graduate student applicants wishing to participate in the Merck Computational Biology and Chemistry graduate program at ... is interested in the application of artificial intelligence to problems in computational molecular biology.. ...
Journal of Computational Biology
... cutting-edge methods in computational biology and bioinformatics. ... Journal of Computational Biology. Co-Editors-in-Chief: Sorin ... Journal of Computational Biology is the leading peer-reviewed journal in computational biology and bioinformatics, publishing ... Special Issue: RECOMB/ISCB Systems Biology, Regulatory Genomics, and DREAM 2014. Journal of Computational Biology is now the ... Journal of Computational Biology is under the editorial leadership of Co-Editors-in-Chief Sorin Istrail, PhD, Brown University ...
COT 4461: Computational Biology
Journal of Computational Biology
... cutting-edge methods in computational biology and bioinformatics. ... Journal of Computational Biology. Co-Editors-in-Chief: Sorin ... Journal of Computational Biology is the leading peer-reviewed journal in computational biology and bioinformatics, publishing ... Journal of Computational Biology is under the editorial leadership of Co-Editors-in-Chief Sorin Istrail, PhD, Brown University ... DNA and Cell Biology DNA and Cell Biology. Combining mechanistic and clinical studies from multiple systems in a single ...
Computational biology
... at The University of Western Australia studies biological questions using mathematics, statistics and ... Understanding biology using computational simulation and analysis. Our research groups address fundamental and applied ... Evolutionary biology. The evolutionary biology research group studies species evolutionary processes such as sexual selection ... We use a range of computational methods and modelling to explore:. *the evolution of resistance to biocides in weeds, pathogens ...
Computational biology and bioinformatics | Cambridge University Press
Computational biology and bioinformatics. Computational biology and bioinformatics. .addthis_counter.addthis_bubble_style { ... Analyzing Network Data in Biology and Medicine An Interdisciplinary Textbook for Biological, Medical and Computational ... Receive email alerts on new books, offers and news in Computational biology and bioinformatics. ... Python Programming for Biology Bioinformatics and Beyond. Stevens, Tim J. Boucher, Wayne Published: February 2015Published: ...
Bioinformatics & Computational Biology | Academics | WPI
Computational Biology program uses cutting-edge quantitative techniques to increase our understanding of biology. ... Director, Bioinformatics & Computational Biology. We designed WPIs BCB Program to educate students to feel comfortable in the ... Bioinformatics involves the collection, management, and analysis of biological data; Computational Biology is the development ... We also have a Bioinformatics & Computational Biology Summer Research Program for High School Students. ...
Computational Genome Biology
Junior Research Group Computational Genome Biology. Dr. Bernd Fischer. Cells are automatically segmented in images from a high- ... We will develop computational methods that aim to predict the phenotypic outcome of drug treatments and combinations of drugs ... The computational methods will be instrumental for cancer proteomics in basic and biomarker research and for the construction ... We will develop computational and statistical methods required for the analysis of emerging, cutting-edge data, especially from ...
bioSyntax: syntax highlighting for computational biology. - PubMed - NCBI
bioSyntax: syntax highlighting for computational biology.. Babaian A1,2, Ebou A3, Fegen A4, Kam HY5, Novakovsky GE6, Wong J7, ... Computational biology requires the reading and comprehension of biological data files. Plain-text formats such as SAM, VCF, GTF ... bioSyntax supports computational scientists in parsing and comprehending their data efficiently and thus can accelerate ...
Computational Biology - Pre-College Programs - Carnegie Mellon University
This page details Carnegie Mellon Universitys Pre-College Computational Biology program and its associated eligibility ... What is computational biology?. Great question! The short answer is the application of high-powered computational approaches to ... Have a strong interests in math, biology, and computer science. * Previous exposure to computational biology isnt required. ... Students in the Pre-College Program in Computational Biology conduct cutting-edge experiments in molecular biology and build ...
Bioinformatics & Computational Biology Alumni Provide Mentorship
... computational biology alumni establish an alumni mentoring program to provide perspective & mentorship to students amid COVID- ... Creating a Student-Alumni Network for the Bioinformatics and Computational Biology Program ... Creating a Student-Alumni Network for the Bioinformatics and Computational Biology Program. ... Elizabeth Ryder considered how to reach out to students and alumni in her field of Bioinformatics and Computational Biology to ...
Center for Computational Biology | Scripps Research
The Center for Computational Biology provides institute-wide bioinformatics analytics for Scripps Research as well as for ... The Center for Computational Biology has wide-ranging experience in creating custom scientific software. Projects for ... Wessel GM, Brayboy L, Fresques T, Gustafson EA, Oulhen N, Ramos I, Reich A, Swartz SZ, Yajima M, Zazueta V., The biology of the ... The computational proteomics focus area provides expertise in analyzing and interpreting data generated by mass spectrometry ...
Computational and Systems Biology of Cancer
... February 8 - 11, 2015. The Fairmont San Francisco. San Francisco, California, USA. ... AACR Special Conference on Computational and Systems Biology of Cancer (B) for a keynote address and reception on Sunday, Feb. ... The field of cancer systems biology has emerged to address the increasing challenge of cancer as a complex, multifactorial ... Prepare for the conference with access to impactful genomics and systems biology articles, published across the AACR journals. ...
Computational Biology - UMMS Biochemistry & Molecular Pharmacology
Computational Biology Research Biochemistry & Molecular Pharmacology University of Massachusetts Medical School ... Computational Biology. What is Computational Biology and Bioinformatics? The goal of computational biology and bioinformatics ... Our PIs that are conducting research in the area of Computational Biology and Bioinformatics. Job Dekker ... Researchers in computational biology and bioinformatics develop algorithms that can predict the behavior of a biological system ...
MIT Department of Biology: 7.91 - Foundations of Computational andSystems Biology
Introduction to computational biology emphasizing the fundamentals of nucleic acid and protein sequence and structural analysis ... Biology at MIT , MIT Home. MIT Department of Biology 31 Ames Street Room 68-132 Cambridge MA 02139 617-253-4701. Contents of ... Subject designed for advanced undergraduates and graduate students with strong backgrounds in either molecular biology or ...
Computational Biology | BSC-CNS
Development of systems biology approaches for modeling and simulating cellular systems. Computational systems biomedicine ... Such computational methods devoted to the interpretation of protein variants will expand our knowledge on the mechanisms by ... New computational methods were developed for the integration of different epigenomic datasets, including histone modifications ... In particular, MelanomaMine detects bio-entities (genes, proteins, mutations and chemicals/drugs) that are relevant for the ...
Computational Systems Biology - WUR
Computational Systems Biology. Systems Biology is based on an integrative approach and applies various computational strategies ... A main goal of the laboratory of Systems and Synthetic Biology is to gain a systems understanding of societal relevant ... To address these questions we build Systems Biology frameworks encompassing different levels of granularity within the fields ... bioinformatics and systems-biology innovations drive algal biotechnology Trends in biotechnology 32,12,617-626 ...
Computational Biology of Transcription Factor Binding | Istvan Ladunga | Springer
Computational Biology of Transcription Factor Binding. Editors. * Istvan Ladunga Series Title. Methods in Molecular Biology. ... In Computational Biology of Transcription Factor Binding, experts in the field examine the basic principles and provide ... Authoritative and easy to use, Computational Biology of Transcription Factor Binding guides scientists working in this area and ... Through great experimental difficulty, weve witnessed rapid, crucial developments at the intersection of computational biology ...
Computational Methods in Molecular Biology, Volume 32 - 1st Edition
Purchase Computational Methods in Molecular Biology, Volume 32 - 1st Edition. Print Book & E-Book. ISBN 9780444828750, ... Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and ... Computational Methods in Molecular Biology, Volume 32 1st Edition. 0 star rating Write a review ... Software and databases for computational biology on the Internet. Appendix B: Suggestions for further reading in computational ...
GenomicsMolecularApproachesInterdisciplinaryPLOS ComputaBioinformatics and computationalAlgorithmsProteomicsApplied mathematicsStatisticalEvolutionaryBiologistsScientistsBiotechnologyJournal of CompInternational Society for Computational BiologyResearchBiological SciencesBiostatisticsComputationGeneticsStructuralExperimentalCarnegie Mellon UniSequenceDataAnalyzeGenomeHigh-throughputIntroduction to computational biologySearchComputer scienceCenter for ComFacultyContentDisciplineProteinSystemsAcademicsAdvancesTheoretical methodsAlgorithmic designProgramTechniquesMaster's
Genomics14
- [1] The field is broadly defined and includes foundations in biology , applied mathematics , statistics , biochemistry , chemistry , biophysics , molecular biology , genetics , genomics , computer science and evolution . (wikipedia.org)
- This data has now become commonplace, particularly in molecular biology and genomics . (wikipedia.org)
- Bioinformatics & Computational Biology at Princeton University includes bioinformatics, functional genomics, and immune system modeling. (princeton.edu)
- Areas of emphasis include the application of machine learning and data mining techniques to large biological knowledge bases, biological modeling, computational aspects of high-throughput laboratory methodologies for large-scale, systematic studies of protein structure and function, analysis of biological image data and computational genomics. (cmu.edu)
- Prof. Raphael research interests include computational cancer biology and the design and application of algorithms for problems in comparative genomics, regulatory genomics, and genetic variation. (brown.edu)
- Studies in computational genomics increasingly rely on analyzing huge quantity of sequences from massive sequencing experiments. (cmu.edu)
- The journal focuses on reviews on advances in computational molecular/structural biology, encompassing areas such as computing in biomedicine and genomics, computational proteomics and systems biology, and metabolic pathway engineering. (ingentaconnect.com)
- Divided into eight sections for convenient searching, the handbook covers methods and algorithms for sequence alignment, string data structures, sequence assembly and clustering, genome-scale computational methods in comparative genomics, evolutionary and phylogenetic trees, microarrays and gene expression analysis, computational methods in structural biology, and bioinformatics databases and data mining. (routledge.com)
- He is also the associate division director of the Institute for Genomics and Systems Biology at Argonne National Laboratory. (anl.gov)
- HIWI Position in Bioinformatics Single cell genomics is revolutionizing biology and medicine. (mytum.de)
- This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses. (wiley.com)
- Phil Blood, widely recognized for his contributions to national genomics and molecular dynamics communities, has been appointed senior director of PSC's Computational Biology Group. (psc.edu)
- As bioinformatics and computational biology bridges data interpretation (e.g. in genomics, transcriptomics, and proteomics) and software development, the section welcomes Original Research and Methods articles describing new analytical approaches and code - which may be as brief as required for accurate presentation. (frontiersin.org)
- CBD faculty and students conduct research in genomics, systems biology, and biological imaging. (wikipedia.org)
Molecular40
- Research in the computational biology program focuses on integrative analysis of high dimensional heterogeneous molecular, imaging, and clinical data to infer predictive models of disease-related phenotypes and functional interventions that induce desired phenotypic transitions. (ohsu.edu)
- As a volume in the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. (springer.com)
- Their work integrates the design of molecular circuity in the test tube and in the cell with the investigation of existing biology pathways. (washington.edu)
- Methods in molecular biology (Clifton, N.J.) , v. 673. (worldcat.org)
- Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. (mit.edu)
- This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. (mit.edu)
- Recent research in molecular biology has produced a remarkably detailed understanding of how living things operate. (mit.edu)
- Computational molecular biology brings together computational, statistical, experimental, and technological methods in order to further scientific discovery and develop new analytical tools for molecular biology. (mit.edu)
- The MIT Press Series on Computational Molecular Biology is intended to provide a unique and effective venue for the rapid publication of monographs, textbooks, edited collections, reference works, and lecture notes of the highest quality. (mit.edu)
- is interested in the application of artificial intelligence to problems in computational molecular biology. (cmu.edu)
- Combining mechanistic and clinical studies from multiple systems in a single resource, the Journal delivers authoritative, peer-reviewed reporting on the latest research in the field of molecular biology. (liebertpub.com)
- This course is an introduction to the study of Algorithmic and Computational problems in molecular biology. (unf.edu)
- Introduction to Computational Molecular Biology , by Setubal & Meidanis, PWS Publishing Company, ISBN 0-534-95262-3. (nyu.edu)
- Students in the Pre-College Program in Computational Biology conduct cutting-edge experiments in molecular biology and build computational approaches from the ground up to analyze the datasets that they obtain from these experiments. (cmu.edu)
- Researchers in computational biology and bioinformatics develop algorithms that can predict the behavior of a biological system and explore the molecular mechanisms of function of nucleic acids and/or proteins. (umassmed.edu)
- Subject designed for advanced undergraduates and graduate students with strong backgrounds in either molecular biology or computer science. (mit.edu)
- Recent methodological advances in the field of molecular and structural biology allow us to use evidence of strong co-evolution as a reliable marker of important evolutionary relationships at molecular level to better understand and predict fundamental aspects of the structure and function of proteins. (bsc.es)
- mputational Molecular Biology (CCMB). (brown.edu)
- The January 2007 issue of Genome Technology magazine named Center for Computational Molecular Biology Assistant Professor Ben Raphael to their annual "Tomorrow's PIs" list. (brown.edu)
- In one of the first major texts in the emerging field of computational molecular biology, Pavel Pevzner covers a broad range of algorithmic and combinatorial topics and shows how they are connected to molecular biology and to biotechnology. (mit.edu)
- Computational Molecular Biology series: computer science and mathematics are transforming molecular biology from an informational to a computational science. (mit.edu)
- Drawing on computational, statistical, experimental, and technological methods, the new discipline of computational molecular biology is dramatically increasing the discovery of new technologies and tools for molecular biology. (mit.edu)
- CALL FOR PAPERS* *3rd International Workshop on* *Biological **Knowledge Discovery and Data Mining** **(BIOKDD'12)* Held in parallel with *23rd International Conference on Database and * *Expert Systems Applications **(**DEXA'12**)* www.dexa.org Vienna, Austria *September 3 - 7, 2012* With the development of Molecular Biology during the last decades, we are witnessing an exponential growth of both the volume and the complexity of biological data. (bio.net)
- Introduction to basic computational methods used for problems arising in molecular biology. (princeton.edu)
- The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. (routledge.com)
- Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology offers comprehensive, systematic coverage of the various techniques and methodologies currently available. (routledge.com)
- The Handbook of Computational Molecular Biology is the first resource to integrate coverage of the broad spectrum of topics in computational biology and bioinformatics. (routledge.com)
- In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. (wiley.com)
- His current research interests include RNA structure and sequence evolution, molecular phylogenetics, theoretical evolutionary biology, and population genetics. (wiley.com)
- The advances in molecular biology and biochemistry that have increased our knowledge of the inner workings of microbes and the better availability of individual-based observations at cell level have brought about an increase in the application of individual-based modelling to microbes. (uea.ac.uk)
- An All-In-One Desktop AMI with hundreds of popular opensource computational molecular biology tools. (amazon.com)
- Molecular dynamics simulations capture the behavior of biological macromolecules in full atomic detail, but their computational demands, combined with the challenge of appropriately modeling the relevant physics, have historically restricted their length and accuracy. (nih.gov)
- SM] J. Setubal and J. Meidanis, Introduction to Computational Molecular Biology , PWS Publishing Co., 1997, 296 pages. (univ-mlv.fr)
- Biopython: freely available Python tools for computational molecular biology and bioinformatics. (nih.gov)
- Now hosted at the San Diego Supercomputer Center at University of California, San Diego, the Society was officially formed in 1997 as an outgrowth of the conference on Intelligent Systems for Molecular Biology (ISMB). (bioportfolio.com)
- The bioinformatics and computational biology program brings together expertise from across Saint Louis University in biology, chemistry, computer science, mathematics and statistics, biochemistry and molecular biology. (slu.edu)
- Molecular Systems Biology 1 - Transcriptional regulation - experiments and quantitative models - This course covers transcriptional regulation from a quantitative perspective. (tum.de)
- Finally, space is given to the application of design concepts towards the realization of solutions for exercises and analysis methodologies in bioinformatics and molecular biology. (unibo.it)
- This chapter elevates the researchers in what way data science play important role in Computational Biology such as Bio-molecular Computation, Computational Photonics, Medical Imaging, Scientific Computing, Structural Biology, Bioinformatics and Bio-Computing etc. (igi-global.com)
- The student should have familiarity with genetic and molecular biology concepts and should be able to work independently using python and R programming tools. (fsu.edu)
Approaches23
- The Computational Biology program leads in the development of innovative computational approaches at OHSU. (ohsu.edu)
- The OHSU computational biology program leads in the development of innovative computational approaches to a range of programs in basic and translational research throughout OHSU. (ohsu.edu)
- His work focuses on mathematical and computational approaches to biological research. (ucl.ac.uk)
- This collection describes key approaches in sparse modeling, focusing on its applications in fields including neuroscience, computational biology, and computer vision. (mit.edu)
- The premier open access, peer reviewed journal focused on interdisciplinary approaches to exploiting the power of big data by applying systems biology and network medicine. (liebertpub.com)
- Our research groups address fundamental and applied questions in biology using big data approaches, and methods and tools from mathematics, statistics and computer science. (edu.au)
- The overarching focus of our program is to provide an unparalleled learning experience for our students by helping them explore the beautiful computational approaches that can be used to analyze biological data. (cmu.edu)
- The field of cancer systems biology has emerged to address the increasing challenge of cancer as a complex, multifactorial disease using sophisticated model-based approaches, ranging from relatively coarse genome-wide regulatory and signaling networks to detailed kinetic models of key pathways. (aacr.org)
- This AACR Special Conference complements and expands the topics explored by the AACR Special Conference on Translation of the Cancer Genome , with which it shares a joint day of sessions, to focus on new innovations in the translation of genomic data using model-based and other systems biology approaches. (aacr.org)
- The Rando lab uses a variety of genome-wide methods to study chromatin structure and function, and epigenetic inheritance, and collaborates extensively with computational biologists to both implement extant analytical approaches as well as design novel types of data analysis. (umassmed.edu)
- 9. Evolutionary approaches to computational biology (R.J. Parsons). (elsevier.com)
- The Computational Biology Track curriculum is designed to help students learn how to leverage mathematical and computational approaches to understand biological and chemical processes. (utsouthwestern.edu)
- Topics include computational approaches to: sequence similarity and alignment, phylogenic inference, gene recognition, gene expression analysis, structure prediction, and whole- and cross-genome analysis. (princeton.edu)
- To study these microbial systems we implement state of the art tools including next generation DNA sequencing and computational approaches. (anl.gov)
- The rise of sound statistical and combinatorial approaches in evolutionary biology has seen considerable improvements of the original ad hoc methods and the ability of the new methods and algorithms to handle ever-larger data sets. (lirmm.fr)
- This branch supports bioinformatics and computational approaches that join biology with the computer sciences, engineering, mathematics, biostatistics and physics as well as general approaches that have the potential for broad applicability and usage by investigators with support from across NIH and other agencies. (nih.gov)
- In conclusion, computational approaches I have used have been successful in testing theories and highlighting potentially promising research directions, but much theoretical and experimental work is still needed to fully understand the evolution of sex in nature. (ens.fr)
- Complex Systems and Computational Biology Approaches to Acute Inflammation presents the current state of the art of multi-disciplinary and systems-oriented research approaches to complex diseases arising from and driven by the acute inflammatory response. (worldcat.org)
- By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation offers a window into the future of biomedical research. (worldcat.org)
- Internships in the Dennis lab will use computational approaches to facilitate an integrated analysis of dynamic nucleosome remodeling and nucleosome sensitivity. (fsu.edu)
- These studies will yield immediate and widely applicable information on the fundamental biology of complex genomes and ultimately new approaches for understanding development and disease. (fsu.edu)
- new computational and theoretical approaches are essential. (yale.edu)
- Computational Biology and Bioinformatics is a field where biological and biomedical problems are addressed using diverse data sources with novel computational, statistical, and theoretical approaches. (yale.edu)
Interdisciplinary12
- Computational biology is different from biological computing , which is a subfield of computer science and computer engineering using bioengineering and biology to build computers , but is similar to bioinformatics , which is an interdisciplinary science using computers to store and process biological data. (wikipedia.org)
- Research in the field of Systems Biology is highly interdisciplinary. (ucl.ac.uk)
- Computational biology is an interdisciplinary field that applies mathematical, statistical, and computer science methods to answer biological questions, and its importance has only increased with the introduction of high-throughput techniques such as automatic DNA sequencing, comprehensive expression analysis with microarrays, and proteome analysis with modern mass spectrometry. (springer.com)
- The only peer-reviewed interdisciplinary publication covering all "OMICS"-related science, such as integrative biology and medicine. (liebertpub.com)
- We are an interdisciplinary and experienced team of computational biologists, experimental scientists, and drug hunters. (genomeweb.com)
- The purpose of this interdisciplinary major is to provide a top-notch educational program for students interested in the areas of computational biology and bioinformatics. (fsu.edu)
- Harvey Mudd's Core curriculum provides mathematical and computational biology majors with a strong multidisciplinary foundation, and the College offers many opportunities for students to engage in interdisciplinary research in biomathematics, computational biology, and quantitative biology. (hmc.edu)
- Bioinformatics and Computational Biology are interdisciplinary fields that apply techniques of computer science, applied mathematics, statistics, and biochemistry to solve biological problems. (diku.dk)
- Our group seeks an interdisciplinary approach, bridging the traditional gaps between physics, mathematics and biology. (unil.ch)
- Data Science and Computational biology is an interdisciplinary program that brings together the domain specific knowledge of science and engineering with relevant areas of computing and bioinformatics. (igi-global.com)
- As a student in the CBB program and the Integrated Graduate Program in Physical and Engineering Biology (PEB), I have seen firsthand the interdisciplinary opportunities available at Yale. (yale.edu)
- As part of the HHMI-NIBIB Interfaces Initiative, CBD received funding from Howard Hughes Medical Institute and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) to develop an interdisciplinary Ph.D. program in computational biology with the University of Pittsburgh, which was founded as the Joint CMU-Pitt Ph.D. Program in Computational Biology in 2005. (wikipedia.org)
PLOS Computa3
- PLoS Computational Biology , an open source journal from the Public Library of Science , has been unveiled today. (medgadget.com)
- PLoS Computational Biology provides a home for important biological research driven by computation-a place where computational biologists can find the best work produced by their colleagues, and where the broader biological community can see the myriad ways computation is advancing our understanding of biological systems. (medgadget.com)
- PLOS) The second annual PLOS Computational Biology Research Prize program has awarded top prizes to three exemplary studies published in 2017. (bioportfolio.com)
Bioinformatics and computational21
- Alicia Howell-Munson has been in the WPI PhD Program for Bioinformatics and Computational Biology since the fall of 2019. (wpi.edu)
- We also developed courses that overlap two or more of these disciplines, each centered on different aspects of the theories, concepts, techniques, and tools of bioinformatics and computational biology. (wpi.edu)
- Dmitry Korkin , PhD, associate professor of computer science and director of the university's bioinformatics and computational biology program, leads the research team. (wpi.edu)
- Integrating Bioinformatics and Computational Biology: Perspective. (ingentaconnect.com)
- The Department currently has 21 faculty in the tenure and research tracks with research interests spanning traditional biostatistics, stochastic modeling, bioinformatics and computational biology. (rochester.edu)
- Bridging biology, the quantitative sciences (such as mathematics, statistics, computer science) and engineering, Bioinformatics and Computational Biology publishes works describing new methods or applications of analytical platforms for complex biological data. (frontiersin.org)
- The discipline of bioinformatics and computational biology sits at the interface between biology, the quantitative sciences (such as mathematics, statistics, computer science) and engineering, and spans levels of investigation from single genes to systems. (frontiersin.org)
- Section Bioinformatics and Computational Biology aims to rapidly publish new methods, research findings, opinions, and hypothesis articles on all aspects of the discipline. (frontiersin.org)
- As is fitting in such a fast-moving, broad discipline, we also seek attempts to connect different sub-fields of bioinformatics, as well as those that examine the history of bioinformatics and computational biology. (frontiersin.org)
- All manuscripts must be submitted directly to the section Bioinformatics and Computational Biology, where they are peer-reviewed by the Associate and Review Editors of the specialty section. (frontiersin.org)
- The Bioinformatics and Computational Biology program has transitioned from Common Fund support. (nih.gov)
- For more information, please visit the websites for the individual National Centers for Biomedical Computing posted on the Bioinformatics and Computational Biology program homepage . (nih.gov)
- Please note that since the Bioinformatics and Computational Biology program is no longer supported by the Common Fund, the program website is being maintained as an archive and will not be updated on a regular basis. (nih.gov)
- Home » Arts and Sciences » Academics » Degrees » Graduate » Bioinformatics and Computational Biology M.S. (slu.edu)
- Bioinformatics and Computational Biology, M.S. (slu.edu)
- The fields of bioinformatics and computational biology have become an important academic discipline for such breakthroughs and a critical part of success for firms in the biotechnology sector. (slu.edu)
- The 30-credit bioinformatics and computational biology program is designed for students with academic backgrounds in the life sciences, mathematics, computer science, health sciences, and statistics. (slu.edu)
- The curriculum consists of a mix of required courses that build a strong foundation in bioinformatics and computational biology and elective classes that allow students to specialize their expertise. (slu.edu)
- As a student in the bioinformatics and computational biology program, students will be required to complete either a research experience with faculty or an internship with a biotech firm in the St. Louis area, which is home to one of the largest concentrations of biotech companies in the country. (slu.edu)
- The Program in Bioinformatics and Computational Biology offers graduate study and research focused on the development and application of computational and mathematical models to biological problems, with an emphasis on the now-available, high-throughput genomic and proteomic data. (umassmed.edu)
- Students receive a rigorous training in modern bioinformatics and computational biology through integration of guided research, coursework and participation in seminar programs. (umassmed.edu)
Algorithms13
- Computational Biology, which includes many aspects of bioinformatics , is the science of using biological data to develop algorithms or models to understand biological systems and relationships. (wikipedia.org)
- Sometimes referred to as genetic algorithms , the research of this field can be applied to computational biology. (wikipedia.org)
- Biology is fast becoming an information science, with large databases and sophisticated algorithms now essential tools in the field. (washington.edu)
- develops algorithms for high-throughput structural biology, accelerating critical steps in determining and modeling protein structures and their dynamics, thereby facilitating faster and better techniques for drug design. (cmu.edu)
- develops probabilistic inference and learning algorithms for computational biology and statistical genetics, and for generic intelligent systems of a wide range of applications. (cmu.edu)
- You can do genetic data analysis, simulations, computational methods of finding new algorithms for mathematical formulas. (wpi.edu)
- This book constitutes the proceedings of the 6th InternationalConference on Algorithms for Computational Biology, AlCoB 2019, held in Berkeley, CA, USA, in May 2019. (springer.com)
- The Weng laboratory builds and applies computational algorithms to integrate deep sequencing genomic, epigenomic, and transcriptomic data to study gene regulation. (umassmed.edu)
- Mathematical and computational concepts, methods, and algorithms are being applied to all areas of basic and clinical life sciences, which results in a variety of research topics. (utsouthwestern.edu)
- Accessible to students in both biology and computer science, it strikes a unique balance between rigorous mathematics and practical techniques, emphasizing the ideas underlying algorithms rather than offering a collection of apparently unrelated problems. (indiebound.org)
- Most of our work is computational, which means we use computer algorithms to process and analyse data. (unil.ch)
- Analysis of computational complexity of algorithms. (unibo.it)
- The written part is composed of two sections: the first section concerns the design and analysis of algorithms and data structures oriented to the maximum computational and space efficiency by adopting the techniques and knowledge learnt during the classes. (unibo.it)
Proteomics4
- In Computational Biology, expert practitioners present a broad survey of computational biology methods by focusing on their applications, including primary sequence analysis, protein structure elucidation, transcriptomics and proteomics data analysis, and exploration of protein interaction networks. (springer.com)
- Specifically, the computational research in proteomics will focus on integrating individual genome sequences into the analysis of proteomic mass spectrometry data. (dkfz.de)
- The computational methods will be instrumental for cancer proteomics in basic and biomarker research and for the construction of predictive, translational platforms for the next generation of individualized, genome-informed drug therapies. (dkfz.de)
- The computational proteomics focus area provides expertise in analyzing and interpreting data generated by mass spectrometry experiments. (scripps.edu)
Applied mathematics3
- Concentration advisors are from the Department of Ecology and Evolutionary Biology, Department of Computer Science, and the Department of Applied Mathematics. (brown.edu)
- This major prepares students for graduate studies in areas including applied mathematics, bioinformatics, computational biology, genome science, mathematical biology, and diverse areas of biology, as well as employment in industry. (hmc.edu)
- The Computational Biology and Bioinformatics Track combines research training opportunities in a range of different fields within the biological sciences, in addition to the computational sciences, biostatistics, and applied mathematics. (yale.edu)
Statistical7
- The computational biology team has advanced training in machine learning, statistical techniques, and a track record of innovation in a biomedical application. (ohsu.edu)
- Journal of Computational Biology is the leading peer-reviewed journal in computational biology and bioinformatics, publishing in-depth statistical, mathematical, and computational analysis of methods, as well as their practical impact. (liebertpub.com)
- We will develop computational and statistical methods required for the analysis of emerging, cutting-edge data, especially from high-throughput functional and genetic assays, and advanced applications of spectrometry. (dkfz.de)
- The goal of computational biology and bioinformatics is to understand biology through the development of mathematical models, the use of computer simulation techniques and statistical analysis of large biological data-sets. (umassmed.edu)
- The mathematical and statistical tools that are used in Computational Biology, e.g., probabilistic models for physical maps, statistical significance of sequence alignments etc. (bio.net)
- The curriculum offers a selection of elective courses that introduce some of the computational, mathematical, and statistical foundations of these applications. (utsouthwestern.edu)
- The statistical, computational and analytical contributions of ongoing studies include microRNA and whole genome epigenetic experiments in swine and human cells. (upenn.edu)
Evolutionary8
- [4] The terms computational biology and evolutionary computation have a similar name, but are not to be confused. (wikipedia.org)
- Unlike computational biology, evolutionary computation is not concerned with modeling and analyzing biological data. (wikipedia.org)
- While evolutionary computation is not inherently a part of computational biology, Computational evolutionary biology is a subfield of it. (wikipedia.org)
- The Mathematical and Computational Evolutionary Biology meetings focus on cutting-edge methodological advances in the domain, along with their foremost applications. (lirmm.fr)
- The theme of this year's edition will be "Towards better trade-offs between speed and accuracy for the analysis of very large data sets in evolutionary biology" . (lirmm.fr)
- The focus is on the mathematical and computational tools and concepts, which form an essential basis of evolutionary studies. (lirmm.fr)
- This well-written book provides a description of modern bioinformatics methods while providing the biology and evolutionary theory necessary to understand how, why, and when these methods work. (wiley.com)
- Students should have background in genetics and preferably evolutionary biology. (fsu.edu)
Biologists2
- Computer scientists, biologists, system biologists and anyone interested in the new world of computational biology: Get together for conversations about the most fascinating topics you can think of, the new frontiers of what hackers can do in the life sciences. (meetup.com)
- The program aims to bridge the gap between wet-lab biologists and computational scientists to their mutual benefit, and prepares students for careers in cutting-edge, highly quantitative biomedical research. (umassmed.edu)
Scientists13
- Authoritative and easy to use, Computational Biology is an ideal guide for all scientists interested in quantitative biology. (springer.com)
- The Computational and Predictive Biology Group brings together and collaborates with scientists from related experimental, computational, and technical disciplines to build increasingly detailed computational models of biological systems. (ornl.gov)
- this their primary research area as well through collaborations between computational and biological scientists. (cmu.edu)
- bioSyntax supports computational scientists in parsing and comprehending their data efficiently and thus can accelerate research output. (nih.gov)
- Tomorrow's life scientists will need deep knowledge of not only the laboratory techniques for generating experimental data but also the rigorous computational techniques necessary to analyze and model these data. (cmu.edu)
- To introduce my professional work and get in touch with scientists or companies who are interested in interaction with a computational biologist. (hccnet.nl)
- As such, it will appeal to basic, translational, computational and clinical scientists from both academia and industry. (aacr.org)
- A secondary audience will be computer scientists developing techniques with applications in biology. (elsevier.com)
- Elements of Computational Systems Biology is a comprehensive reference covering the computational frameworks and techniques needed to help research scientists and professionals in computer science, biology, chemistry, pharmaceutical science, and physics solve complex biological problems. (wiley-vch.de)
- Consequently, the most effective research teams of the future will be composed of scientists who are aware of computational techniques, together with computation experts who have a basic understanding of the science behind the project. (pointloma.edu)
- Modern biology poses many challenging problems for the computer scientists. (southampton.ac.uk)
- You will work in a team of several computational scientists and experimentalists who can provide data along the full chain from material design up to in vivo data. (nature.com)
- His newest work, The Inner Workings of Life (Cambridge University Press), discusses in a casual style the new field of systems biology for interested non-scientists. (elsevier.com)
Biotechnology5
- Professor Manning is an assistant professor for the Department of Biology & Biotechnology. (wpi.edu)
- Professor Rao is the associate dean of graduate studies and a professor in the department of Biology & Biotechnology. (wpi.edu)
- so people can make changes to their yard, learn what flowers to plant, and tell us how do we conserve lands to increase bee diversity," Robert Gegear , professor of biology and biotechnology, told the T&G . (wpi.edu)
- Applicants should hold a Master of Science degree in Chemistry, Biochemistry, Biotechnology, Pharmaceutical Science, Chemical Engineering or an equivalent background that provides a strong basis of computational techniques and structural biology knowledge. (dtu.dk)
- Biotechnology, Pharma and Biopharma News - Research - Science - Lifescience ://Biotech-Biopharma-Pharma: Sr. Scientist, Computational Biology .MA-Cambridge, ROLE SUMMARY As part of t. (bioportfolio.com)
Journal of Comp1
- Journal of Computational Biology, 18(3):323 333, March 2011. (brown.edu)
International Society for Computational Biology1
- The International Society for Computational Biology (ISCB) is incorporated in the United States as a 501(c)(3) non-profit corporation, and registered in the state of California as a Charitable Trust. (bioportfolio.com)
Research15
- Understand the uses of modelling in biology with reference to examples drawn across the spectrum of bioscience research. (ucl.ac.uk)
- He delivers the Dynamic Biological Systems module to UCL undergraduates and the SysMIC eLearning course which provides training in quantitative biology aimed at the postgraduate research community. (ucl.ac.uk)
- Biological research is increasingly dependent on, and driven by, evolving computational analysis and prediction. (ornl.gov)
- The research opportunities that span across the computer science, mathematics, and biology departments are wonderful opportunities for BCB students to recognize their specific strengths over time and gives flexibility in expanding their interests. (wpi.edu)
- She looks forward to working with students both in class and in the lab to gain a better understanding of cancer cell biology and to make meaningful contributions to cancer research. (wpi.edu)
- Biological and medical research have become fully fledged computational disciplines. (cmu.edu)
- The Center for Computational Biology provides institute-wide bioinformatics analytics for Scripps Research as well as for external collaborators. (scripps.edu)
- This comprehensive reference presents cutting-edge and long-ranging research in computational system. (wiley-vch.de)
- This comprehensive reference presents cutting-edge and long-ranging research in computational systems biology. (wiley-vch.de)
- The Annual International Conference on Research in Computational Biology -- RECOMB -- is one of the top conferences in computational biology. (brown.edu)
- This work tends to be published either in methods journals that are not read by experimentalists or in one of the numerous journals reporting novel biology, each of which publishes only small amounts of computational research. (medgadget.com)
- The coursework presents computational research tools in the context of scientific problems. (pointloma.edu)
- These unique programs offer co-mentorship for portions of the dissertation research to graduate students affiliated with a life science or clinical lab in the areas of computational biology and information technology. (utsouthwestern.edu)
- In my research I have used computational and theoretical methods to test theories about the evolution of sex, predict when sex will evolve based on those theories and describe the effects of recombination on genomes' genetic architecture. (ens.fr)
- The Computational Biology Group (CBG) is a research group embedded in the Department of Computational Biology at the University of Lausanne . (unil.ch)
Biological Sciences1
- Carnegie Mellon University offers educational programs in computational biology through the undergraduate degree in Biological Sciences with a Computational Option or the B.S. Degree in Biological Sciences/Computational Biology, the Professional Masters Program in Computational Biology, and the Merck Graduate Program in Computational Biology and Chemistry . (cmu.edu)
Biostatistics2
- To support ICB3, designate an online gift to "Other" and indicate "Institute for Computational Biology, Biostatistics, and Bioinformatics" or contact us to discuss your interests. (umass.edu)
- Welcome to the home page of the Department of Biostatistics and Computational Biology, located in the School of Medicine and Dentistry at the University of Rochester! (rochester.edu)
Computation4
- The Allen School and the University of Washington are at the forefront of exciting innovations at the intersection of computation and biology to advance scientific discovery, develop new diagnostics and therapeutics, and usher in a new era of personalized medicine. (washington.edu)
- The term computational science (distinct from computer science) refers to the use of computation to solve problems in the sciences. (pointloma.edu)
- Folker Meyer is a computational biologist at Argonne National Laboratory and a senior fellow at the Computation Institute at the University of Chicago. (anl.gov)
- A basic knowledge of biology and genetics and skills of computation programing are required. (fsu.edu)
Genetics1
- Student should also have good organizational and note-taking skills along with a basic knowledge of genetics and biology. (fsu.edu)
Structural3
- Introduction to computational biology emphasizing the fundamentals of nucleic acid and protein sequence and structural analysis, also including an introduction to the analysis of complex biological systems. (mit.edu)
- 2014. Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: Role of Asn181 and Ile335 validated by spectroscopic and computational studies . (ub.edu)
- A 3-year PhD scholarship in Structural and Computational Biology is available at Department of Chemistry, Technical University of Denmark. (dtu.dk)
Experimental3
- His work addresses issues ranging from the experimental design level to the systems biology level. (cmu.edu)
- The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers with a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. (worldcat.org)
- There is a distinct lack of detailed macromolecular measurement protocols, including comparisons to alternative assays and methodologies, as well as tools to convert the experimental data into biochemical reactions for computational biology applications. (mdpi.com)
Carnegie Mellon Uni2
- Because Carnegie Mellon University is holding its summer session online this year, we are transitioning the 2020 offering of the PreCollege program in computational biology to an online format. (cmu.edu)
- The Computational Biology Department (CBD) is a division within the School of Computer Science at Carnegie Mellon University in Pittsburgh, Pennsylvania, United States. (wikipedia.org)
Sequence4
- Computational biology has been used to help sequence the human genome, create accurate models of the human brain, and assist in modeling biological systems. (wikipedia.org)
- Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and protein sequence analysis is growing every day. (elsevier.com)
- Content: Dynamic Programming techniques as they apply to problems in Computational Biology, e.g., sequence alignment, prediction of RNA Secondary Structure, comparison of philogenetic trees, etc. (bio.net)
- In biology, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and usually assumed to be related to biological function of the macromolecule. (wikipedia.org)
Data21
- Computational biology involves the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, ecological, behavioral, and social systems. (wikipedia.org)
- It involves the development and application of computational, mathematical and data-analytical methods for modeling and simulation of biological structures. (wikipedia.org)
- The introduction of high-throughput methods has transformed biology into a data-rich science. (mit.edu)
- Our contribution is the development of computational statistics for high-dimensional data, including feature selection tools, differential testing and network modeling. (dkfz.de)
- Computational biology requires the reading and comprehension of biological data files. (nih.gov)
- Pre-College Computational Biology provides extensive training in both cutting-edge laboratory experiments to generate biological data and the computational analysis of the data that these experiments generate. (cmu.edu)
- The Rhind lab predicted from computational analysis of genome-wide replication kinetics data that multiple MCM initiation complexes are loaded at each replication origin and confirmed that prediction experimentally. (umassmed.edu)
- Systems Biology is based on an integrative approach and applies various computational strategies to integrate heterogeneous data to model and discover properties of biological systems. (wur.nl)
- We have built a systems biology platform that leverages deep omics data we generate from unique human cohorts to identify drug targets that impact aging. (genomeweb.com)
- It is also accessible to undergraduate and graduate students in machine learning, data mining, bioinformatics, computational biology, and systems biology courses. (wiley-vch.de)
- Computational students increase their knowledge of a particular scientific area, and science students increase their abilities in areas like statistics, scripting, and data management. (pointloma.edu)
- In this paper we discuss how different computational tools and methods can be made to work together integrating different types of data, mining these data for biological information, and assisting in pathway reconstruction and biological hypotheses generation. (ingentaconnect.com)
- Data from biology comes in various forms: nucleotide and amino-acid sequences, macromolecular structures, measurements from high-throughput experiments and curated literature in the form of publications and functional annotations. (southampton.ac.uk)
- It is nowadays widely acknowledged that computational modelling will play a key role in extracting useful information from vast amounts of such diverse types of data. (southampton.ac.uk)
- To harness the full potential of these developments, new computational methods specifically tailored towards the analysis of single cell omics data are essential. (mytum.de)
- Job: HIWI-Position, 5h/week (more or less hours also possible, flexible, home office possible) Qualifications: Applicants should be students of bioinformatics/computational biology and be highly motivated to contribute to single-cell RNA-seq data analyses and preparation of manuscripts for publication. (mytum.de)
- The course is structured with live lessons, illustrating the theoretical aspects of the topics concerning the data structures and algorithmic design for computational biology. (unibo.it)
- After the introduction of basic definitions and concepts, the course illustrates the design of simple data structures and the relationship with the costs of execution (computational efficiency) and memory occupation (space) on the computer architecture. (unibo.it)
- Jyothi, Singaraju and Bhargavi P. "Data Science and Computational Biology. (igi-global.com)
- Data Science and Computational Biology. (igi-global.com)
- Students can participate on computational studies of genomic data sets that were generated to understand complex reproductive behaviors. (fsu.edu)
Analyze2
- This required the development of new computational methods in order to quickly analyze and interpret relevant information. (wikipedia.org)
- The Royer laboratory uses computational methods to analyze protein structures and, currently, to design inhibitors to the cancer target, C-terminal Binding Protein (CtBP), a transcriptional co-regulator involved in regulation of hundreds of genes. (umassmed.edu)
Genome6
- From sequencing the human genome to modeling living organisms, biology has gone digital, and WPI's Bioinformatics & Computational Biology (BCB) program is at the forefront of this digital revolution. (wpi.edu)
- Attendees of the AACR Special Conference on Translation of the Cancer Genome (A) will joined by the attendees of the AACR Special Conference on Computational and Systems Biology of Cancer (B) for a keynote address and reception on Sunday, Feb. 8, then for joint sessions on Monday, Feb. 9. (aacr.org)
- Computational systems biology is an emerging discipline that is evolving quickly due to recent advances in biology such as genome sequencing, high-throughput technologies, and the recent development of sophisticated computational methodologies. (wiley-vch.de)
- 13 The Impact of Whole Genome In Silico Screening for Nuclear Receptor-Binding Sites in Systems Biology (Carsten Carlberg and Merja Heinaniemi). (wiley-vch.de)
- The computational challenges faced by the human genome project and Alan Turing's contribution to morphogenesis are classic examples of such roles. (southampton.ac.uk)
- Computational biology has developed rapidly during the last two decades following the genomic revolution which culminated in the sequencing of the human genome. (routledge.com)
High-throughput1
- High-throughput sequencing and advanced imaging are moving computational biology very fast," observed Nick Nystrom, interim director of PSC. (psc.edu)
Introduction to computational biology1
- This book offers an introduction to computational biology using visual python (an extremely powerful and simple language with graphical capabilities) which focuses on a variety of different types of computer models and how they can be applied to model biological systems. (textbookrevolution.org)
Search1
- Computational gene prediction using neural networks and similarity search (Y. Xu, E.C. Uberbacher). (elsevier.com)
Computer science12
- The new field of Artificial Chemistries draws from chemistry, biology, computer science, mathematics, and other disciplines to work toward that goal. (mit.edu)
- Biology, Computer Science, and Mathematics. (wpi.edu)
- We designed WPI's BCB Program to educate students to feel comfortable in the language, concepts, and techniques of three distinct disciplines: biology, mathematics, and computer science. (wpi.edu)
- These chapters target topics and solutions in computer science, mathematics, physics, biology, and the pharmaceutical and biomedical areas. (wiley-vch.de)
- PLNU's computational science minor is offered to students who are majoring in a science (biology, chemistry, physics, psychology) or a computational field (mathematics, computer science) and who wish to become conversant in the complementary discipline. (pointloma.edu)
- Eighteen (18) hours of electives chosen from Biology, Computer Science, Math and/or Statistics. (fsu.edu)
- it is rigorous without being too formal, and has an accessible and broad coverage of topics from both a computer science and a biology perspective. (wiley.com)
- The book introduces biological and algorithmic ideas together, linking issues in computer science to biology and thus capturing the interest of students in both subjects. (indiebound.org)
- Harvey Mudd students interested in the interface between biology, mathematics, and computer science may pursue the Mathematical and Computational Biology Major, which is jointly administered by the biology, mathematics, and computer science departments. (hmc.edu)
- Students who choose this major become immersed in the scientific and intellectual cultures of biology, computer science, and mathematics, and the major is sufficiently flexible to allow students to concentrate in a particular area of interest. (hmc.edu)
- Students in this major have one advisor from the biology department and one advisor from either the mathematics or computer science departments. (hmc.edu)
- Established in 2007 by Robert F. Murphy as the Lane Center for Computational Biology with funding from Raymond J. Lane and Stephanie Lane, CBD became a department within the School of Computer Science in 2016. (wikipedia.org)
Center for Com1
- The Center for Computational Biology has wide-ranging experience in creating custom scientific software. (scripps.edu)
Faculty2
- Allen School faculty and students collaborate with researchers in biology and medicine on a wide range of computational problems that will ultimately enable us to understand complex biological systems. (washington.edu)
- Undergraduate and graduate students work alongside expert faculty researchers to use cutting-edge, quantitative techniques to increase our understanding of biology and translate this knowledge into meaningful solutions. (wpi.edu)
Content1
- Content: Basic Background material in Biology. (bio.net)
Discipline1
- Candidates should have a PhD in computational biology or a related discipline, and a strong background in bioinformatics, machine learning, and statistics, as well as an interest in the biological processes that drive aging. (genomeweb.com)
Protein2
Systems23
- Due to the availability of dense 3D measurements via technologies such as magnetic resonance imaging (MRI), computational anatomy has emerged as a subfield of medical imaging and bioengineering for extracting anatomical coordinate systems at the morphome scale in 3D. (wikipedia.org)
- Computational biomodeling is a field concerned with building computer models of biological systems. (wikipedia.org)
- Computational biomodeling aims to develop and use visual simulations in order to assess the complexity of biological systems. (wikipedia.org)
- To tackle such problems we also develop new technical methods and systems such as KBase (the Department of Energy Systems Biology Knowledgebase), and work with researchers at the Oak Ridge Leadership Computing Facility to develop exascale applications that run on some of the world's fastest supercomputers. (ornl.gov)
- The Neural Systems Laboratory aims to advance our understanding of the brain using computational models and simulations, and apply this knowledge to the task of building intelligent robotic systems and brain-computer interfaces (BCIs). (washington.edu)
- This book constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology, CMSB 2008, held in Rostock, Germany, in September 2008. (springer.com)
- Computational Biology is the development of quantitative models of biological systems. (wpi.edu)
- My name is Hans van Beek and I am a computational systems biologist at the Vrije Universiteit Amsterdam. (hccnet.nl)
- A main goal of the laboratory of Systems and Synthetic Biology is to gain a systems understanding of societal relevant microorganisms and microbial ecosystems and to translate this knowledge into applications of biotechnological, medical and environmental interest. (wur.nl)
- It is written by leading experts and covers a range of topics from modeling and learning biological systems to the impact of computational systems biology on drug design and medicine. (wiley-vch.de)
- Chapters provide a multidisciplinary approach and range from analysis, modeling, prediction, reasoning, inference, and exploration of biological systems to the applications of computational systems biology. (wiley-vch.de)
- and describes state-of-the-art software tools for systems biology. (wiley-vch.de)
- 1 Advances in Computational Systems Biology (Huma M. Lodhi). (wiley-vch.de)
- 2 Models in Systems Biology: The Parameter Problem and the Meanings of Robustness (Jeremy Gunawardena). (wiley-vch.de)
- Computational systems biology is the term that we use to describe computational methods to identify, infer, model, and store relationships between the molecules, pathways, and cells (''systems'') involved in a living organism. (google.de)
- Based on this definition, the field of computational systems biology has been in existence for some time. (google.de)
- Two events have occurred to bring the field of computational systems biology to theforefront. (google.de)
- Integration of the different datasets through computational methods is required to extract biological information that is relevant from a systems biology perspective. (ingentaconnect.com)
- The Microbial Systems and Computational Biology group aims to understand the distributions of functions that natural microbial communities exhibit at different scales. (anl.gov)
- An introduction to systems biology: design principles of biological circuits. (southampton.ac.uk)
- The burgeoning fields of complex systems analysis and computational biology offer researchers a pathway towards addressing the Translational Dilemma. (worldcat.org)
- Praise for the first edition: … superb, beautifully written and organized work that takes an engineering approach to systems biology. (routledge.com)
- Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. (routledge.com)
Academics1
- Read More at: https://www.wpi.edu/academics/departments/bioinformatics-computational-biology/m. (wpi.edu)
Advances1
- A team led by professor Rajesh Rao published the results of a study that employs computational methods to explain human choices in group decision-making in Science Advances . (washington.edu)
Theoretical methods1
- In this chapter, an overview is presented of theoretical methods used in computational enzymology to calculate potential energy profiles and barrier heights, potentials of mean force, two-dimensional free energy surfaces, minimum free energy paths or rate constants with inclusion of quantum nuclear effects. (rsc.org)
Algorithmic design2
- Computational Biology involves the analysis and discovery of biological phenomena using computational tools, and the algorithmic design and analysis of such tools. (brown.edu)
- Some programming and algorithmic design techniques are introduced and discussed in terms of computational and space complexity: iterative, recursive, divide et impera, greedy, dynamic programming. (unibo.it)
Program3
- The Pre-College Computational Biology program offers an unparalleled experience for high school students to explore this relationship in a university setting. (cmu.edu)
- The program seeks to achieve two goals: 1) to develop an understanding of the issues associated with developing biologically meaningful computational models, and 2) to give students the broad-based education that is needed to create a set of models directed towards solving a practical biomedical problem. (fsu.edu)
- The branch also collaborates with the National Science Foundation to support a program in mathematical biology. (nih.gov)
Techniques1
- It demonstrates that relatively few design techniques can be used to solve a large number of practical problems in biology, and presents this material intuitively. (indiebound.org)
Master's1
- Dr. Eberhard O. Voit studied biology and mathematics at Cologne University, Germany, where he received Master's degrees in biology and mathematics, as well as a Ph.D. in developmental and theoretical biology. (elsevier.com)