Blood Transfusion: The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)Blood Transfusion, Autologous: Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)Erythrocyte Transfusion: The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.Transplantation, Autologous: Transplantation of an individual's own tissue from one site to another site.Platelet Transfusion: The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.Exchange Transfusion, Whole Blood: Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.Blood Loss, Surgical: Loss of blood during a surgical procedure.Blood Component Transfusion: The transfer of blood components such as erythrocytes, leukocytes, platelets, and plasma from a donor to a recipient or back to the donor. This process differs from the procedures undertaken in PLASMAPHERESIS and types of CYTAPHERESIS; (PLATELETPHERESIS and LEUKAPHERESIS) where, following the removal of plasma or the specific cell components, the remainder is transfused back to the donor.Blood Transfusion, Intrauterine: In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).Blood Banks: Centers for collecting, characterizing and storing human blood.Blood DonorsBlood Grouping and Crossmatching: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.Operative Blood Salvage: Recovery of blood lost from surgical procedures for reuse by the same patient in AUTOLOGOUS BLOOD TRANSFUSIONS. It is collected during (intraoperatively) or after completion of (postoperatively) the surgical procedures.Fetofetal Transfusion: Passage of blood from one fetus to another via an arteriovenous communication or other shunt, in a monozygotic twin pregnancy. It results in anemia in one twin and polycythemia in the other. (Lee et al., Wintrobe's Clinical Hematology, 9th ed, p737-8)Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.Postoperative Hemorrhage: Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.Hemoglobins: The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Antifibrinolytic Agents: Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Jehovah's Witnesses: Members of a religious denomination founded in the United States during the late 19th century in which active evangelism is practiced, the imminent approach of the millennium is preached, and war and organized government authority in matters of conscience are strongly opposed (from American Heritage Dictionary of the English Language, 4th ed). Jehovah's Witnesses generally refuse blood transfusions and other blood-based treatments based on religious belief.Blood Preservation: The process by which blood or its components are kept viable outside of the organism from which they are derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Blood Group Incompatibility: An antigenic mismatch between donor and recipient blood. Antibodies present in the recipient's serum may be directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984).Leukocyte Transfusion: The transfer of leukocytes from a donor to a recipient or reinfusion to the donor.Hemodilution: Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.Blood Safety: The degree to which the blood supply for BLOOD TRANSFUSIONS is free of harmful substances or infectious agents, and properly typed and crossmatched (BLOOD GROUPING AND CROSSMATCHING) to insure serological compatibility between BLOOD DONORS and recipients.Anemia, Neonatal: The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation.Plateletpheresis: The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor.Perioperative Care: Interventions to provide care prior to, during, and immediately after surgery.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Hematopoietic Stem Cell Transplantation: Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.Blood Substitutes: Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.beta-Thalassemia: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.Isoantibodies: Antibodies from an individual that react with ISOANTIGENS of another individual of the same species.Erythropoietin: Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.Erythroblastosis, Fetal: A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.Bone Marrow Transplantation: The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.Hemostatics: Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.Hemorrhage: Bleeding or escape of blood from a vessel.Leukocyte Reduction Procedures: The removal of LEUKOCYTES from BLOOD to reduce BLOOD TRANSFUSION reactions and lower the chance of transmitting VIRUSES. This may be performed by FILTRATION or by CYTAPHERESIS.Hemostasis, Surgical: Control of bleeding during or after surgery.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Red Cross: International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.Surgical Procedures, Elective: Surgery which could be postponed or not done at all without danger to the patient. Elective surgery includes procedures to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risk to patients, e.g., cosmetic or contraceptive surgery.Postoperative Care: The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Fetomaternal Transfusion: Transplacental passage of fetal blood into the circulation of the maternal organism. (Dorland, 27th ed)Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Transplantation, Homologous: Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.Platelet Count: The number of PLATELETS per unit volume in a sample of venous BLOOD.Blood-Borne Pathogens: Infectious organisms in the BLOOD, of which the predominant medical interest is their contamination of blood-soiled linens, towels, gowns, BANDAGES, other items from individuals in risk categories, NEEDLES and other sharp objects, MEDICAL WASTE and DENTAL WASTE, all of which health workers are exposed to. This concept is differentiated from the clinical conditions of BACTEREMIA; VIREMIA; and FUNGEMIA where the organism is present in the blood of a patient as the result of a natural infectious process.Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.Arthroplasty, Replacement, Knee: Replacement of the knee joint.Aprotinin: A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)Rh Isoimmunization: The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.Hematinics: Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.Plasma: The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.Length of Stay: The period of confinement of a patient to a hospital or other health facility.Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.Cardiac Surgical Procedures: Surgery performed on the heart.Thrombocytopenia: A subnormal level of BLOOD PLATELETS.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Infant, Newborn: An infant during the first month after birth.Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)Chelation Therapy: Therapy of heavy metal poisoning using agents which sequester the metal from organs or tissues and bind it firmly within the ring structure of a new compound which can be eliminated from the body.Postpartum Hemorrhage: Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).Lymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.Surgical Procedures, Operative: Operations carried out for the correction of deformities and defects, repair of injuries, and diagnosis and cure of certain diseases. (Taber, 18th ed.)Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.Hepatitis C Antibodies: Antibodies to the HEPATITIS C ANTIGENS including antibodies to envelope, core, and non-structural proteins.Blood Coagulation Disorders: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.Stem Cell Transplantation: The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.Hematocrit: The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.Phlebotomy: The techniques used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders such as erythrocytosis, hemochromatosis, polycythemia vera, and porphyria cutanea tarda.Reticulocyte Count: The number of RETICULOCYTES per unit volume of BLOOD. The values are expressed as a percentage of the ERYTHROCYTE COUNT or in the form of an index ("corrected reticulocyte index"), which attempts to account for the number of circulating erythrocytes.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Graft Survival: The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.Hepatectomy: Excision of all or part of the liver. (Dorland, 28th ed)Arthroplasty, Replacement, Hip: Replacement of the hip joint.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Blood Cell Count: The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.Erythrocytes: Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Hepatitis, Viral, Human: INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).Melphalan: An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Peptic Ulcer Hemorrhage: Bleeding from a PEPTIC ULCER that can be located in any segment of the GASTROINTESTINAL TRACT.Seroepidemiologic Studies: EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.Lymphocyte Culture Test, Mixed: Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.Recurrence: The return of a sign, symptom, or disease after a remission.Fibrin Tissue Adhesive: An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.Intraoperative Period: The period during a surgical operation.Tattooing: The indelible marking of TISSUES, primarily SKIN, by pricking it with NEEDLES to imbed various COLORING AGENTS. Tattooing of the CORNEA is done to colorize LEUKOMA spots.Erythrocyte Count: The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.Rh-Hr Blood-Group System: Erythrocyte isoantigens of the Rh (Rhesus) blood group system, the most complex of all human blood groups. The major antigen Rh or D is the most common cause of erythroblastosis fetalis.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Hepatitis B: INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Iron Chelating Agents: Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.Christianity: The religion stemming from the life, teachings, and death of Jesus Christ: the religion that believes in God as the Father Almighty who works redemptively through the Holy Spirit for men's salvation and that affirms Jesus Christ as Lord and Savior who proclaimed to man the gospel of salvation. (From Webster, 3d ed)Cyclophosphamide: Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.Fetoscopy: Endoscopic examination, therapy or surgery of the fetus and amniotic cavity through abdominal or uterine entry.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Erythrocyte Aging: The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days.Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.HLA Antigens: Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Bone Marrow Purging: Techniques for the removal of subpopulations of cells (usually residual tumor cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic BONE MARROW TRANSPLANTATION.Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.Epistaxis: Bleeding from the nose.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Isotonic Solutions: Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Isoantigens: Antigens that exist in alternative (allelic) forms in a single species. When an isoantigen is encountered by species members who lack it, an immune response is induced. Typical isoantigens are the BLOOD GROUP ANTIGENS.Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.Peripheral Blood Stem Cell Transplantation: Transplantation of stem cells collected from the peripheral blood. It is a less invasive alternative to direct marrow harvesting of hematopoietic stem cells. Enrichment of stem cells in peripheral blood can be achieved by inducing mobilization of stem cells from the BONE MARROW.ABO Blood-Group System: The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.Transplantation Conditioning: Preparative treatment of transplant recipient with various conditioning regimens including radiation, immune sera, chemotherapy, and/or immunosuppressive agents, prior to transplantation. Transplantation conditioning is very common before bone marrow transplantation.Blood Group Antigens: Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties.Infant, Premature: A human infant born before 37 weeks of GESTATION.Colonialism: The aggregate of various economic, political, and social policies by which an imperial power maintains or extends its control over other areas or peoples. It includes the practice of or belief in acquiring and retaining colonies. The emphasis is less on its identity as an ideological political system than on its designation in a period of history. (Webster, 3d ed; from Dr. J. Cassedy, NLM History of Medicine Division)Splenectomy: Surgical procedure involving either partial or entire removal of the spleen.Cytotoxicity, Immunologic: The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid "killer" cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement.Plasma Substitutes: Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.Coombs Test: A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.Thrombelastography: Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Remission Induction: Therapeutic act or process that initiates a response to a complete or partial remission level.Hemosiderosis: Conditions in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the MONONUCLEAR PHAGOCYTE SYSTEM, without demonstrable tissue damage. The name refers to the presence of stainable iron in the tissue in the form of hemosiderin.Hospital Mortality: A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.T-Lymphocytes: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).Acute Disease: Disease having a short and relatively severe course.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Nephrostomy, Percutaneous: The insertion of a catheter through the skin and body wall into the kidney pelvis, mainly to provide urine drainage where the ureter is not functional. It is used also to remove or dissolve renal calculi and to diagnose ureteral obstruction.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Blood Specimen Collection: The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.Perioperative Period: The time periods immediately before, during and following a surgical operation.Trauma Centers: Specialized hospital facilities which provide diagnostic and therapeutic services for trauma patients.Antisickling Agents: Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.Vacuum: A space in which the pressure is far below atmospheric pressure so that the remaining gases do not affect processes being carried on in the space.Lymphocyte Activation: Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Blood Volume: Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.Hemoglobinometry: Measurement of hemoglobin concentration in blood.Histocompatibility Testing: Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed)Statistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)Patient Identification Systems: Organized procedures for establishing patient identity, including use of bracelets, etc.Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)T-Lymphocytes, Cytotoxic: Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.Critical Illness: A disease or state in which death is possible or imminent.Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Shock, Hemorrhagic: Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.Blood Component Removal: Any procedure in which blood is withdrawn from a donor, a portion is separated and retained and the remainder is returned to the donor.Medical Audit: A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of medical care.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.Jaundice, Neonatal: Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.Papilloma, Inverted: A mucosal tumor of the urinary bladder or nasal cavity in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded than in other papillomas. (Stedman, 25th ed)Disease-Free Survival: Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.Etoposide: A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.Blood: The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.Leukapheresis: The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor.Angiodysplasia: Acquired degenerative dilation or expansion (ectasia) of normal BLOOD VESSELS, often associated with aging. They are isolated, tortuous, thin-walled vessels and sources of bleeding. They occur most often in mucosal capillaries of the GASTROINTESTINAL TRACT leading to GASTROINTESTINAL HEMORRHAGE and ANEMIA.Babesia microti: A species of protozoa infecting humans via the intermediate tick vector IXODES scapularis. The other hosts are the mouse PEROMYSCUS leucopus and meadow vole MICROTUS pennsylvanicus, which are fed on by the tick. Other primates can be experimentally infected with Babesia microti.Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Hematopoietic Stem Cell Mobilization: The release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell transplantation. Hematopoietic growth factors or chemotherapeutic agents often are used to stimulate the mobilization.Leukocyte Count: The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.Blood Coagulation Tests: Laboratory tests for evaluating the individual's clotting mechanism.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.Iron Compounds: Organic and inorganic compounds that contain iron as an integral part of the molecule.Filtration: A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.Resuscitation: The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)Lymphocytes: White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.Clinical Protocols: Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy.Granulocyte Colony-Stimulating Factor: A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).Otorhinolaryngologic Surgical Procedures: Surgery performed on the ear and its parts, the nose and nasal cavity, or the throat, including surgery of the adenoids, tonsils, pharynx, and trachea.Melena: The black, tarry, foul-smelling FECES that contain degraded blood.Disease Transmission, Infectious: The transmission of infectious disease or pathogens. When transmission is within the same species, the mode can be horizontal or vertical (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).Safety: Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.Hepacivirus: A genus of FLAVIVIRIDAE causing parenterally-transmitted HEPATITIS C which is associated with transfusions and drug abuse. Hepatitis C virus is the type species.Kidney Transplantation: The transference of a kidney from one human or animal to another.Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
List of MeSH codes (E02)
... platelet transfusion MeSH E02.095.135.164 --- blood transfusion, autologous MeSH E02.095.135.264 --- blood transfusion, ... blood component transfusion MeSH E02.095.135.140.275 --- erythrocyte transfusion MeSH E02.095.135.140.425 --- leukocyte ... intrauterine MeSH E02.095.135.469 --- exchange transfusion, whole blood MeSH E02.095.135.750 --- plasma exchange MeSH E02.095. ... transfusion MeSH E02.095.135.140.425.445 --- lymphocyte transfusion MeSH E02.095.135.140.650 --- ...
Most blood for transfusion is collected as whole blood. Autologous donations are sometimes transfused without further ... "Circular of Information for the use of Human Blood and Blood Components" (PDF). AABB, ARC, America's Blood Centers. p. 16. ... A blood bank is a center where blood gathered as a result of blood donation is stored and preserved for later use in blood ... see List of blood donation agencies and List of blood donation agencies in the United States. Whole blood or blood with RBC, is ...
April 1998: p. 30 "Autologous (self-donated) Blood as an Alternative to Allogeneic (donor-donated) Blood Transfusion". AABB. ... separation of whole-blood components). Donation may be of whole blood (WB), or of specific components directly (the latter ... "Transfusion handbook, Summary information for Red Blood Cells". National Blood Transfusion Committee. Retrieved 2008-06-02. " ... Blood substitutes James Harrison (blood donor) List of blood donation agencies Men who have sex with men blood donor ...
Jehovah's Witnesses and blood transfusions
2.2 per cent of blood volume) is permitted. He has questioned why donating blood and storing blood for autologous transfusion ... Fractions from red blood cells: Hemoglobin, the oxygen-carrying component of red blood cells. Fractions from white blood cells: ... platelets or plasma for either allogeneic or autologous transfusion. Transfusions of autologous blood part of a "current ... Blood introduced directly into the veins circulates and functions as blood, not as nutrition. Hence, blood transfusion is a ...
Jehovah's Witnesses and blood transfusions
... platelets or plasma for either allogeneic or autologous transfusion.. *Transfusions of autologous blood part of a " ... Jehovah's Witnesses' literature teaches that their refusal of transfusions of whole blood or its four primary components-red ... Blood introduced directly into the veins circulates and functions as blood, not as nutrition. Hence, blood transfusion is a ... In 1945, the application of the doctrine on blood was expanded to prohibit blood transfusions of whole blood, whether ...
Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood ... Blood transfusions typically use sources of blood: one's own (autologous transfusion), or someone else's (allogeneic or ... American Association of Blood Banks (AABB) British Blood Transfusion Society (BBTS) International Society of Blood Transfusion ... Blood transfusions fell into obscurity for the next 150 years. The science of blood transfusion dates to the first decade of ...
Blood transfusions can be traditionally classified as autologous, where the blood donor and transfusion recipient are the same ... The blood is centrifuged, the plasma components are immediately reinfused, and the corpuscular elements, principally red blood ... Blood transfusion begins by the withdrawal of 1 to 4 units of blood (1 unit = 450 ml of blood) several weeks before competition ... Nearly 50% of autologous donations are not used by the donor and are discarded, as current standards do not allow transfusion ...
Incremental Blood Loss Possible with ANH.(BLH - BLs). BLs. Maximum blood loss without ANH before homologous blood transfusion ... To maintain the normovolemia, the withdrawal of autologous blood must be simultaneously replaced by a suitable hemodilute. ... When debating the use of colloid or crystalloid, it is imperative to think about all the components of the starling equation: Q ... Blood. Main article: Blood. Blood is a complex liquid. Blood is composed of plasma and formed elements. The plasma ...
In such a case ANH can save a maximum of 1.1 packed red blood cell unit equivalent, and homologous blood transfusion is ... See below for a glossary of the terms used.) To maintain the normovolemia, the withdrawal of autologous blood must be ... When debating the use of colloid or crystalloid, it is imperative to think about all the components of the starling equation: Q ... Diastolic blood pressure BPsys = Systolic blood pressure Differences in mean blood pressure are responsible for blood flow from ...
An exchange transfusion is a blood transfusion in which the patient's blood or components of it are exchanged with (replaced by ... the new blood or blood products come from another person or persons, via donated blood); autologous exchange transfusion is ... other blood or blood products. Most simple blood transfusions involve adding blood or blood products without removing any. In ... as most autologous transfusions involve no exchange. An exchange transfusion requires that the patient's blood can be removed ...
Improved management of blood components, leading to decreased wastage. References. *^ a b "Patient Blood Management" ... contains smaller amounts of red blood cells. The collected autologous blood product, which contains red blood cells, platelets ... "Clinical Transfusion: 2 Establishing and Implementing a PBM strategy". International Society of Blood Transfusion.. ... "Patient Blood Management". www.blood.gov.au. Retrieved 22 August 2018.. *^ "Patient Blood Management". JPAC. Retrieved 22 ...
Platelet components can have had the white blood cells partially removed (leucodepleted) which decreases the risk of having a ... However, this benefit was only seen in certain patient groups, and people undergoing an autologous stem cell transplant derived ... "Patient Blood Management Guidelines , National Blood Authority". www.blood.gov.au. Archived from the original on 2016-01-15. ... Unlike other blood products demand for platelet transfusions appears to be increasing in several countries around the world. An ...
Fresh frozen plasma
In rare instances, human immunodeficiency virus (HIV) is transmitted by blood transfusions and possibly by FFP. Allergic or ... This includes measures such as autologous donation before elective surgery, the infusion of shed blood, and the realization ... possibly including decreased availability of whole blood due to widespread acceptance of the concept of component therapy. ... is a blood product made from the liquid portion of whole blood. It is used to treat conditions in which there are low blood ...
Most blood for transfusion is collected as whole blood. Autologous donations are sometimes transfused without further ... "Circular of Information for the use of Human Blood and Blood Components" (PDF). AABB, ARC, America's Blood Centers. p. 16. ... A blood bank is a center where blood gathered as a result of blood donation is stored and preserved for later use in blood ... Insufficient transfusion efficacy can result from red blood cell (RBC) blood product units damaged by so-called storage lesion- ...
Induced stem cells
"Proof of principle for transfusion of in vitro-generated red blood cells". Blood. 118 (19): 5071-9. doi:10.1182/blood-2011-06- ... "An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state". Blood. 121 (21): 4257- ... Of concern for autologous use, in particular in the elderly most in need of tissue repair, MSCs decline in quantity and quality ... RBC transfusion is necessary for many patients. However, to date the supply of RBCs remains labile. In addition, transfusion ...
Cross match of blood is routine also, as a high percentage of patients receive a blood transfusion. Pre-operative planning ... Loosening of the components: the bond between the bone and the components or the cement may break down or fatigue. As a result ... Rheumasurgery Arthroplasty Orthopedic surgery Joint replacement registry Autologous chondrocyte implantation Microfracture ... They are also made so that if a shard were to break off of one of the two ceramic components, they would be noticeable through ...
Autolgous blood transfusion, Nurs Times, 13-19; 84(2):33-5 Jan 1988 Autologous Blood Transfusion Education Program, Training ... Blood can be drawn from the patient just prior to surgery and then separated. The separated blood components which have been ... However the first documented use of autologous blood transfusion was in 1818 when an Englishman, Rey Paul Blundell, salvaged ... This unsophisticated method resulted in a 75% mortality rate, but it marked the start of autologous blood transfusion. During ...
Platelet components can have had the white blood cells partially removed (leucodepleted) which decreases the risk of having a ... and people undergoing an autologous stem cell transplant derived no obvious benefit. Despite prophylactic platelet ... "Patient Blood Management Guidelines , National Blood Authority". www.blood.gov.au. Archived from the original on 2016-01-15. ... "Blood transfusion , Guidance and guidelines , NICE". www.nice.org.uk. Archived from the original on 2016-01-16. Retrieved 2016- ...
Further research into this technique should have potential benefits to gene therapy, blood transfusion, and topical medicine. ... Autologous stem cell based treatments for tendon injury, ligament injury, and osteoarthritis in dogs have been available to ... Scaffolds composed of natural and artificial components are seeded with mesenchymal stem cells and placed in the defect. Within ... The FDA has approved five hematopoietic stem-cell products derived from umbilical cord blood, for the treatment of blood and ...
Transplantable organs and tissues
Early transfusions used Whole Blood, but modern medical practice is to use only components of the blood. The operation is ... 1999). "Autologous haematopoietic stem cell transplants for autoimmune disease--feasibility and transplant-related mortality. ... Blood transfusion is the process of transferring blood or blood-based products from one person into the circulatory system of ... such as massive blood loss due to trauma, or can be used to replace blood lost during surgery. Blood transfusions may also be ...
... blood transfusion, and topical medicine. Regrowing teeth. In 2004, scientists at King's College London discovered a way ... June 1999). "Autologous mesenchymal stem cell-mediated repair of tendon". Tissue Eng. 5 (3): 267-77. doi:10.1089/ten.1999.5.267 ... Scaffolds composed of natural and artificial components are seeded with mesenchymal stem cells and placed in the defect. Within ... The FDA has approved five hematopoietic stem-cell products derived from umbilical cord blood, for the treatment of blood and ...
Autologous conditioned plasma
... in comparison with whole blood) and that is extracted from whole blood using a separation process. Main components of ACP ... Transfusion. 2005; 45: 1759-1767. Edwards D, et al: Transforming Growth Factor Beta Modulates the Expression of Collagenase and ... Autologous conditioned plasma (ACP) is a platelet-rich plasma that is extracted from autologous blood using centrifugation. It ... Autologous Conditioned Plasma (ACP) is an autologous blood plasma ‒ occurring naturally within the body ‒ that is conditioned ...
Fecal microbiota transplant
They have included bacterial blood infections, fever, exacerbation of IBD in people who also had that condition, and mild GI ... The introduction of normal flora results in durable implantation of these components. Another postulated mechanism entails the ... A modified form of fecal microbiota transplant (autologous restoration of gastrointestinal flora-ARG) commenced development as ... Previous terms for the procedure include fecal bacteriotherapy, fecal transfusion, fecal transplant, stool transplant, fecal ...
Induced pluripotent stem cell
In 2014, type O red blood cells were synthesized at the Scottish National Blood Transfusion Service from iPSC. The cells were ... The benefits of using autologous iPSCs are that there is theoretically no risk of rejection and that it eliminates the need to ... a necessary component in the telomerase protein complex. Pluripotency: iPSCs were capable of differentiation in a fashion ... Although a pint of donated blood contains about two trillion red blood cells and over 107 million blood donations are collected ...
Blood vessels constrict in tissue that becomes cold and dilate in warm tissue, altering blood flow to the area. Thus keeping ... Transfusion and Apheresis Science. 30 (2): 145-51. doi:10.1016/j.transci.2004.01.004. PMID 15062754. Alleva, Renata; Nasole, ... "Autologous cultured keratinocytes suspensions accelerate re-epithelialization in the diabetic pig". Journal of the American ... disintegrated bacterial biofilm as well as harmful exudate components, known to slow the healing process. The treatment also ...
Dearden C (July 2012). "How I treat prolymphocytic leukemia". Blood. 120 (3): 538-51. doi:10.1182/blood-2012-01-380139. PMID ... Adoptive T-cell therapy is a form of passive immunization by the transfusion of T-cells (adoptive cell transfer). They are ... This treatment cleans CD19 positive cells from the body (including the disease). Antibodies are a key component of the adaptive ... Gardner TA, Elzey BD, Hahn NM (April 2012). "Sipuleucel-T (Provenge) autologous vaccine approved for treatment of men with ...
Cord Blood for Neonatal Hypoxic-Ischemic Encephalopathy, Autologous Cord Blood Cells for Hypoxic Ischemic Encephalopathy Study ... better establishment of red blood cell volume, and decreased need for blood transfusion". In January 2017, a revised Committee ... Engineers sometimes use the term to describe a complex or critical cable connecting a component, especially when composed of ... 2008). "Autologous Umbilical Cord Blood Infusion for Type 1 Diabetes". Exp. Hematol. 36 (6): 710-715. doi:10.1016/j.exphem. ...
Cord Blood for Neonatal Hypoxic-Ischemic Encephalopathy Archived 2011-08-12 at Wikiwix, Autologous Cord Blood Cells for Hypoxic ... better establishment of red blood cell volume, and decreased need for blood transfusion". In January 2017, a revised Committee ... Engineers sometimes use the term to describe a complex or critical cable connecting a component, especially when composed of ... Storage of cord bloodEdit. Main article: Cord blood. The blood within the umbilical cord, known as cord blood, is a rich and ...
Autologous immune enhancement therapy
Journal of Hematology and Blood Transfusion. doi:10.1007/s12288-013-0327-3. Explore 'Killer Cell' Treatment to Cure rare ... abnormal genetic components or any other factor such as radiation or a constant irritation. Cancer is still a leading cause of ... Autologous immune enhancement therapy (AIET) is a treatment method in which immune cells are taken out from the patient's body ... "Autologous immune enhancement therapy in recurrent ovarian cancer with metastases; 18 months follow-up- A case report". " ...
Rejection of blood transfusions. Main article: Jehovah's Witnesses and blood transfusions. Jehovah's Witnesses refuse blood ... epidural blood patch, plasmapheresis, blood labeling or tagging and platelet gel (autologous) ... The Watch Tower Society provides pre-formatted durable power of attorney documents prohibiting major blood components, in which ... Though Jehovah's Witnesses do not accept blood transfusions of whole blood, they may accept some blood plasma fractions at ...
Limfocyty T regulatorowe, wolna encyklopedia
Pretransplant blood transfusion without additional immunotherapy generates CD25+CD4+ regulatory T cells: a potential ... Human T regulatory cells can use the perforin pathway to cause autologous target cell death. „Immunity". 21 (4), s. 589-601, ... Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression. „J Exp Med". 204 (6), s. 1303-1310 ... DOI: 10.1182/blood-2004-07-2583. PMID: 15572590. *↑ a b c S. Hori, T. Nomura, S. Sakaguchi. Control of regulatory T cell ...
If the procedure is expected to result in significant blood loss, an autologous blood donation may be made some weeks prior to ... In 2014, the Lancet Commission on Global Surgery was launched to examine the case for surgery as an integral component of ... Blood or blood expanders may be administered to compensate for blood lost during surgery. Once the procedure is complete, ... Blood. Triple test. Quad test. Percutaneous umbilical cord blood sampling. Apt test. Kleihauer-Betke test. Lung maturity. ...
Though Jehovah's Witnesses do not accept blood transfusions of whole blood, they may accept some blood plasma fractions at ... epidural blood patch, plasmapheresis, blood labeling or tagging and platelet gel (autologous) "Our Kingdom Ministry" (PDF). ... The Watch Tower Society provides pre-formatted durable power of attorney documents prohibiting major blood components, in which ... Members are directed to refuse blood transfusions, even in "a life-or-death situation". Jehovah's Witnesses accept non-blood ...
Autologous blood transfusion | definition of autologous blood transfusion by Medical dictionary
... autologous blood transfusion explanation free. What is autologous blood transfusion? Meaning of autologous blood transfusion ... Looking for online definition of autologous blood transfusion in the Medical Dictionary? ... See: blood doping. See also: transfusion. transfusion. the introduction of whole blood or blood components directly into the ... autologous blood transfusion. Also found in: Dictionary, Thesaurus, Encyclopedia. autologous blood transfusion. 1. The ...
Evaluation of clinical, hematological, and biochemical changes following autologous blood transfusion in goats |...
The risk of pathogen transmission can be reduced using autologous ... Blood transfusion is an important remedy to manage animals with ... Blood component transfusions. Vet Clin Food Anim 21:615-622 CrossRef Divers TJ (2005) Blood component transfusions. Vet Clin ... Collection and transfusion of blood and blood components in the United States. Transf 38:625-636 CrossRef Wallace EL, Churchill ... Collection and transfusion of blood and blood components in the United States. Transf 38:625-636 CrossRef ...
Stem Cell Oncology: Proceedings of the International Stem Cell and Oncology Conference (ISCOC, 2017), December 1-2, 2017, Medan...
Collection of stem cells in (autologous) donors by apheresis H. Vrielink. Transfusion of blood components in a stem cell ... Use of C-Reactive Protein (CRP) and haematological score to predict positive blood cultures in sepsis ... The effect of andaliman fruit extract to blood glucose levels of mice with type 1 diabetes ...
Autologous blood transfusion. Linklater. This lecture covers in detail the advantages and disadvantages of autologous blood ... 8:30-9 - Hot Topic: Whole blood or component therapy?. Linklater. Transfusion medicine has evolved over many years, and current ... storage and administration of component parts of whole blood, specifically, red blood cells, plasma and platelets. These ... 9:00-9:50 - Transfusion medicine: Year in Review???. Linklater. Transfusion medicine is a fast-growing field with new studies ...
Blood gas analysis, transcutaneous | definition of blood gas analysis, transcutaneous by Medical dictionary
What is blood gas analysis, transcutaneous? Meaning of blood gas analysis, transcutaneous medical term. What does blood gas ... Looking for online definition of blood gas analysis, transcutaneous in the Medical Dictionary? blood gas analysis, ... autologous blood transfusion.. reconstituted blood. A blood product used in transfusion therapy composed of components of blood ... Occult blood, Safe blood, Strawberry cream blood, Umbilical cord blood, Whole blood, Yellow blood. Cf Snake blood. blood (blŭd ...
Comparing Fresh Random Platelets and Autologous Cryopreserved Thrombosol Treated Autologous Platelets
Determine the corrected count increment of autologous transfused platelets that had been stored by cryopreservation with Th ... Platelets are an important component of blood. Transfusions with platelets help to control. bleeding in thrombocytopenic ... autologous platelet transfusion. After the transfusion, you will have additional blood. drawn (around 1-2 teaspoons) to check ... Before the transfusion you will have blood drawn (around 1-2 teaspoons) to check on the. number of platelets in your blood. You ...
Transfusion Options - Blood Bank/Transfusion Medicine - Clinical Laboratories - URMC Clinical Labs - University of Rochester...
Autologous blood, which is your own blood. There are two different ways in which your own blood may be used in a transfusion: * ... Allogeneic blood, which comes from an anonymous donor. *Blood components, including: *Red blood cells (RBCs) ... Blood Bank/Transfusion Medicine / Patient Blood Management / Transfusion Options ... Transfusion Options The ability to transfuse blood depends upon a safe and ready blood supply. The University of Rochester ...
Blood boosting | British Journal of Sports Medicine
In autologous transfusion, 1 to 4 units (450-1800 ml) of blood are withdrawn then centrifuged. The plasma components are ... The combination of rHuEpo and autologous blood transfusion may allow enhanced autologous transfusion,2 which may explain the ... blood transfusions and were used at the 1994 Winter Olympics.39 However, autologous RBC transfusion remains notoriously ... To detect sudden autologous transfusion requires mobile blood testing facilities at competition sites, as used at the Sydney ...
FAQ: Leucodepletion of red cells and platelets | Australian Red Cross Lifeblood
Reduction in the incidence of bacterial contamination of blood components. *Possible reduced risk of transfusion-associated ... Are autologous collections leucodepleted?. All autologous collections collected by Lifeblood are provided as leucodepleted ... from blood components using special filters.. Lifeblood performs leucodepletion during the manufacturing of blood components ... Are all blood components leucodepleted by Lifeblood?. All red cells and platelet components (both apheresis and pooled ...
Safety, Tolerability, and Immunogenicity of Zoster Vaccine Live (ZOSTAVAX™) in Healthy Adults in India (V211-025) - Full Text...
BLOOD TRANSFUSION. the infusion of blood or blood components into an individual for the treatment of a medical condition. ... the transfer of blood or blood components from one individual to another (or back to the donor, in the case of autologous ... COMPLETE BLOOD COUNT (CBC). an inventory of the cellular components of the blood, including red blood cell count, hematocrit ... Transfusions may be homologous (from a donor) or autologous (previously stored blood from the recipient). ...
Jehovah's Witnesses and blood transfusions - Wikipedia
2.2 per cent of blood volume) is permitted. He has questioned why donating blood and storing blood for autologous transfusion ... Fractions from red blood cells: Hemoglobin, the oxygen-carrying component of red blood cells. Fractions from white blood cells: ... platelets or plasma for either allogeneic or autologous transfusion. Transfusions of autologous blood part of a "current ... Blood introduced directly into the veins circulates and functions as blood, not as nutrition. Hence, blood transfusion is a ...
List of MeSH codes (E02) - Wikipedia
... platelet transfusion MeSH E02.095.135.164 --- blood transfusion, autologous MeSH E02.095.135.264 --- blood transfusion, ... blood component transfusion MeSH E02.095.135.140.275 --- erythrocyte transfusion MeSH E02.095.135.140.425 --- leukocyte ... intrauterine MeSH E02.095.135.469 --- exchange transfusion, whole blood MeSH E02.095.135.750 --- plasma exchange MeSH E02.095. ... transfusion MeSH E02.095.135.140.425.445 --- lymphocyte transfusion MeSH E02.095.135.140.650 --- ...
2020 World Transfusion Diagnostics Market for 40 Immunohematology and NAT Assays: US, Europe, Japan--Supplier Shares and...
Genetically Engineered Blood Components. 10. Blood Preservation. 11. Autologous Blood Transfusion/Freezing. VII. France Blood ... Blood Typing and Grouping Reagent Market Forecast. By Major Test. U.S.A., Military Blood Banks Blood Typing. And Grouping ... U.K., Blood Banks Blood Typing. And Grouping Test Volume Forecast. U.K., Commercial/Private Laboratories. Blood Typing and ... Italy, Hospital Laboratories Blood. Typing and Grouping Reagent Market Forecast. By Major Test. Italy, Blood Banks Blood Typing ...
Blood Donations and Blood Banking | University Hospitals
This is so that your blood is available in case you need a transfusion. Donating blood for yourself is called an autologous ... What are the components of blood?. Blood or one of its components may be transfused. Each component serves many functions. ... What is blood banking?. A blood bank is a place where blood is collected and stored before it is used for transfusions. Blood ... blood and blood products are safe before they are used. Blood banking also determines the blood type. The blood is also tested ...
Billing for Blood and Transfusion Services: Frequently Asked Questions and Answers
... can you charge 36430 for the transfusion, 86890 for the autologous blood and a P-code for the particular component (ex. RBC, ... Billing for Autologous Blood. Question: For outpatient autologous transfusions should we bill CPT 86890 at the time of ... blood components from suppliers that charge for the liquid blood or collects their own blood and charges for the liquid blood ... a blood component HCPCS code (P code) should be attached to this revenue code when billing for transfused blood components as ...
2020 Asia-Pacific Transfusion Diagnostics Market for 40 Immunohematology and NAT Assays: A 17-Country Analysis--Supplier Shares...
9. Genetically Engineered Blood Components. 10. Blood Preservation. 11. Autologous Blood Transfusion/Freezing. VII. Country ... Japan Hospital Laboratories Blood. Typing and Grouping Test Volume Forecast. Japan Blood Banks Blood Typing. And Grouping Test ... Japan Hospital Laboratories Blood. Typing and Grouping Reagent Market. Forecast by Major Test. Japan Blood Banks Blood Typing ... Total Blood Bank Test Volume and Reagent. Sales Forecast by Test Category. Hong Kong All Market Segments Blood Typing. And ...
Growth Opportunities in Transfusion Diagnostic Testing
... the transfusion diagnostics market will undergo significant transformation, which will result from the convergence of several ... Blood Preservation. 13. Autologous Blood Transfusion/Freezing. D. Worldwide Market Overview. 1. Business Environment. 2. Market ... Genetically Engineered Blood Components. a. Albumin. b. Factor VIII. c. Alpha-2 Antiplasmin. d. Antithrombin III. e. Factor IX ... U.K., Blood Banks Blood Typing And Grouping Test Volume Forecast. U.K., Commercial/Private Laboratories Blood Typing and ...
Curriculum & Graduation Career-Level Competencies - UPMC Chautauqua WCA
Topics include blood group systems, hemolytic diseases, blood donor and autologous transfusion practices. Theory, procedures ... and techniques in the cross-matching of transfused blood and in blood component therapy are covered.. ... The study of the cellular and formed elements of blood, body fluids and the blood-forming tissues and their relation to the ... IMMUNOHEMATOLOGY (BLOOD BANK). 5 Credits. Coursework emphasizes the theory, practice and diagnostic principles in antibodies ...
Jehovah's Witnesses and blood transfusions - Wikipedia
... platelets or plasma for either allogeneic or autologous transfusion.. *Transfusions of autologous blood part of a " ... Jehovahs Witnesses literature teaches that their refusal of transfusions of whole blood or its four primary components-red ... Blood introduced directly into the veins circulates and functions as blood, not as nutrition. Hence, blood transfusion is a ... In 1945, the application of the doctrine on blood was expanded to prohibit blood transfusions of whole blood, whether ...
Lymphedema People ™ • View topic - Blood Glossary
Patients who receive their own Blood receive the safest possible Blood transfusions. Reactions due to components of Blood such ... Autologous Blood - Autologous Blood (donation) is Blood drawn from one individual to be given back to that individual, or a ... Transfusion - Replacing Blood or Blood components a body has lost in surgery, through an accident, or as a result of medical ... Blood cells which comprise the minor portion of whole Blood. Blood Count - The complete Blood count, or CBC. Blood Culture - ...
Perioperative Autologous Cell Salvage (PACS) | American Red Cross
... as a key component of blood management programs and are an effective transfusion option for surgical patients who need blood ... Blood Types. Blood Components. What Happens to Donated Blood. Blood and Diversity. History of Blood Transfusion. Iron and Blood ... Blood FAQs. Blood Donor Community. Learn About Blood. Blood Facts and Statistics. ... Perioperative Autologous Cell Salvage (PACS). PACS services are recognized as a key component of blood management programs and ...
Patent US6280622 - System for using ligands in particle separation - Google Patents
To reduce risks associated with infusing blood components from a foreign donor, some of these transfusions are autologous, ... blood components, a peripheral blood cell collection, a bone marrow blood cell collection, and/or blood components removed from ... blood removed from an umbilical cord, and/or blood components, such as a peripheral blood cell collection or bone marrow blood ... blood components are separated or harvested from other blood components using a centrifuge. The centrifuge rotates a blood ...
Live Zoster Vaccine in HIV-Infected Adults on Antiretroviral Therapy - Full Text View - ClinicalTrials.gov
Receipt of immunoglobulin or any blood products, other than autologous blood transfusion, given during the 5 months prior to ... History of allergy/sensitivity, or hypersensitivity to any vaccine component, including gelatin or neomycin ... At some visits, blood and urine collection, and a clinical assessment will occur. Antiretroviral medications are not provided ... VZV-specific cellular immune responses in peripheral blood mononuclear cells (PBMC) were tested by ELISpot assay in a subset of ...
Basics of Blood Management
... is the first book dedicated to blood ... enhancing the patients own blood, effective management of ... introduces the reader to the concept of blood management and explains how to improve patient outcomes by avoiding undue blood ... Basics of Blood Management - Book Information By: Petra Seeber and Aryeh Shander Commended in the Haematology category at the ... 15 The use of autologous blood. 16 Cell salvage. 17 Blood banking. 18 Transfusions. Part I: cellular components and plasma. 19 ...
Blood System Flashcards by Kevin Hixson | Brainscape
Whole blood or cells are taken from a donor and infused into a patient. Autologous transfusion is the patients own blood. Prior ... Separation of blood into component parts and removal of a select portion from the blood. Plasmapharesis - plasma, ... Collection and later reinfusion of a patients own blood or blood components ... Antigen on red blood cells of Rh-positive individuals. The factor was first identified in the blood of a rhesus monkey ...
Clinical transfusion practice update: haemovigilance, complications, patient blood management and national standards | The...
The use of trauma transfusion pathways for blood component transfusion in the civilian population: a systematic review and meta ... Preoperative autologous blood donation is recommended only for patients with very specific transfusion needs, such as those ... Survival of trauma patients after massive red blood cell transfusion using a high or low red blood cell to plasma transfusion ... Transfusion 2011; 51: 1122-1123.. *43. Wang D, Sun J, Solomon SB, et al. Transfusion of older stored blood and risk of death: a ...
Platelet Rich Plasma (PRP) Matrix Grafts
... matrix grafts application techniques in musculoskeletal medicine utilize the concentrated healing components of a patients own ... blood-reintroduced into a specific site-to regenerate tissue and speed the healing process. ... in 1987 as an autologous transfusion component after an open heart operation to avoid homologous blood product transfusion.1 It ... Autologous PRP gel stipulates the use of autologous thrombin. The author considers a PRP Matrix Graft to include gel or no gel ...
Improving the usefulness of a laboratory tool to match donors and patients | Canadian Blood Services
Keywords: Red blood cell, transfusion, alloimmunization, laboratory, rare blood.. Want to know more? Contact Dr. Holovati at ... These blood cells can be from the patient (called "autologous" monocytes) or from someone else (called "allogeneic" monocytes ... Buffy coats are produced from whole blood donations as part of the process to make platelet components. Buffy coats from ... immune white blood cells obtained from peripheral blood mononuclear cells that are isolated from whole blood immediately before ...
US Patent # 5,795,571. Composition containing autologous thrombin blood fraction for use in a medical procedure - Patents...
... if the blood fraction is employed as a component of a fibrin sealant, then autologous fibrinogen can be utilized, thereby ... Gibble et al., "Fibrin glue: the perfect operative sealant?" Transfusion 30(8):741-747 (1990). .. Gestring et al., "Autologous ... The thrombin blood fraction can be prepared from whole blood. It is preferred that the whole blood be obtained from a single ... The thrombin blood fraction can be prepared from whole blood and is impure in that it contains blood proteins other than ...
DonationApheresisDonorsReactionsAutotransfusionPatient'sComplicationsPerioperativePlatelet TransfusionRecipientsCryoprecipitatePreoperativeAntibodiesAspects of transfusionHomologousCollection and reinfusionImmunohematologyOne'sAllogenic bloodRecombinant human erythropoietinInfectionAccept blood transfusionsAntigensDiagnostics MarketMorbidity and mortaAplastic AnemiaElectiveAdverseAllogeneic transfusionRBCsPreservationImmunePathologyAlternativesRisksPracticeProcedureSurgeryFreezingDiseasesInfectious disease
- Donating blood for yourself is called an autologous donation. (uhhospitals.org)
- Autologous Blood - Autologous Blood (donation) is Blood drawn from one individual to be given back to that individual, or a close very Blood match designee, as the need for transfusion arises. (lymphedemapeople.com)
- Blood donors are typically unpaid volunteers, but they may also be paid by commercial blood donation and processing enterprises, such as independent blood banks and donor centers. (surgeryencyclopedia.com)
- Purpose: Preoperative autologous blood donation (PAD) is important for reducing exposure to allogenic blood in cardiac surgery. (fujita-hu.ac.jp)
- The independent factors for perioperative allogenic blood transfusion in these patients included the pre-donation hemoglobin value, the preoperative platelet count, and the lowest hemoglobin value during cardiopulmonary bypass. (fujita-hu.ac.jp)
- Conclusion: Even with PAD for elective cardiac surgery, patients whose pre-donation hemoglobin value and preoperative platelet count are low may require allogenic blood transfusion. (fujita-hu.ac.jp)
- Takami, Y & Masumoto, H 2009, ' Predictors of allogenic blood transfusion in elective cardiac surgery after preoperative autologous blood donation ', Surgery Today , vol. 39, no. 4, pp. 306-309. (fujita-hu.ac.jp)
- Providing your own blood before surgery is called autologous (pronounced: aw-TAHL-uh-gus) blood donation. (kidshealth.org)
- Another option for blood transfusions is called directed donation . (kidshealth.org)
- For directed donation, the donor must have a blood type that is compatible with the recipient's. (kidshealth.org)
- In addition, the American Red Cross and other donation groups test donated blood for viruses like HIV (the virus that causes AIDS), hepatitis B, hepatitis C, syphilis, and West Nile virus. (kidshealth.org)
- 12 Unlike preoperative autologous blood donation, USB does not undergo storage, and this may result in significant differences with respect to its immunomodulatory effects. (asahq.org)
- For a safe blood service in our country, where comprehensive laboratory tests are neither possible nor pragmatic, it is best to switch over to 100% voluntary donations, as it is now established that only voluntary non-remunerated regular donation is the safest. (sbtcup.org)
- Small tokens, refreshments and reimbursement of the direct travel costs are compatible with voluntary, non-remunerated blood donation. (sbtcup.org)
- Voluntary" blood donation refers to "unpaid, non-remunerated" blood donation. (sbtcup.org)
- A voluntary non-remunerated blood donor who has donated at least three times, the last donation being within the previous year, and continues to donate regularly at least once per year. (sbtcup.org)
- The professional blood donation is banned in our country w.e.f. 1st January 1998. (sbtcup.org)
- A person who is not willing to donate blood on his/her own, but is being forced by their superiors or employer for donation. (sbtcup.org)
- When you arrive at the donation site, a nurse will check your pulse, blood pressure, temperature and hemoglobin (iron level). (uniprix.com)
- The donation itself lasts about 10 minutes, during which time 450 ml of blood is collected. (uniprix.com)
- Some basic criteria are used to ensure that blood donation is safe for recipients and donors. (cancer.ca)
- When someone donates their blood for their own use, it is called autologous blood donation or autotransfusion. (cancer.ca)
- this is called "autologous" blood donation. (nypress.com)
- autologous donation is most often employed in surgery on bones, blood vessels, the urinary tract and the heart, when the likelihood of transfusion is high. (nypress.com)
- this form of blood donation is good for the patient, but it's beneficial to society, too. (nypress.com)
- volunteers donate almost all the blood transfused in the united states using current screening and donation procedures. (nypress.com)
- A hemolytic anemia patient should seek further medical advice before making an autologous donation. (elitecme.com)
- Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. (rochester.edu)
- Circulating blood removed from the body is spun in a machine to separate the components in a process called apheresis. (memorialhospitaljax.com)
- Platelet (PLT) transfusions totaled 9,052,000 PLT concentrate equivalent units, of which 66.5 percent were PLTs from apheresis. (nih.gov)
- II-12 Growing Need for Blood Propels Demand for Blood Collection Tubes II-13 Reagents - Key to Functionality of Hematology Analyzers II-13 Increasing Cancer Incidence Drives Use of Apheresis Equipment and Supplies. (prnewswire.com)
- Transfusion-related acute lung injury (TRALI) mitigation strategies include the deferral of female donors from apheresis platelet (PLT) donations and the distribution of plasma for transfusion from male donors only. (pubmedcentralcanada.ca)
- A TRALI mitigation policy that only defers female apheresis PLT donors with previous pregnancies and HLAs would result in an approximately 5% decrease in the inventory of apheresis PLTs, but would eliminate a large proportion of components that are associated with TRALI. (pubmedcentralcanada.ca)
- The AABB also recommended mitigation steps for apheresis platelet (PLT) components. (pubmedcentralcanada.ca)
- 2. Responsibilities The Blood Bank resident is expected to attempt to problem solve all therapeutic apheresis, immunohematology, coagulation and blood component therapy problems on the blood bank core rotation in a timely fashion. (docplayer.net)
- The University of Rochester receives its supply of blood from healthy donors who give to the American Red Cross. (rochester.edu)
- We are a nonprofit hospital obtaining our blood products through another nonprofit blood bank which collects blood through volunteer donors. (aabb.org)
- About 6.8 million volunteers are blood donors each year. (uhhospitals.org)
- Who are the blood donors? (uhhospitals.org)
- Most blood donors are volunteers. (uhhospitals.org)
- Volunteer blood donors must meet certain criteria. (uhhospitals.org)
- To avoid these serious reactions, the blood and tissue type of recipients and donors is determined before transfusion or transplantation. (blood.ca)
- Blood registry refers to the collection and sharing of data about donated blood and donors. (surgeryencyclopedia.com)
- Donors who have been determined to be temporarily or permanently ineligible to donate blood are listed in a confidential national data base known as the Donor Deferral Register. (surgeryencyclopedia.com)
- Healthy donors may be called upon to donate periodically to help maintain the overall blood supply or when their specific blood type is needed. (surgeryencyclopedia.com)
- Donors are advised to give blood only once in an eight-week period to maintain the iron stores in their blood. (surgeryencyclopedia.com)
- Autologous donors may donate more often if it is determined by their physician to be to their benefit. (surgeryencyclopedia.com)
- All donors are carefully screened to make sure there is a suitable blood type match and to prevent any transmissible diseases or other complications. (surgeryencyclopedia.com)
- Living donors must be physically fit, in good general health, and have no existing disorders such as diabetes, high blood pressure, cancer, kidney disease, or heart disease. (surgeryencyclopedia.com)
- There are approximately 9.5 million volunteer blood donors (2006). (medcentral.org)
- A place where blood may be collected from donors, typed, separated into components, stored, and prepared for transfusion to recipients. (sabm.org)
- Blood banks collect blood from volunteer donors. (uwhealth.org)
- This is why blood banks are always looking for donors. (uwhealth.org)
- Donors give blood at local blood banks, at community centers during blood drives, or through the American Red Cross. (kidshealth.org)
- There is no medical or scientific evidence that blood from directed donors is safer or better than blood from volunteer donors. (kidshealth.org)
- Voluntary blood donors are the cornerstone of a safe and adequate supply of blood and blood products. (sbtcup.org)
- The safest blood donors are voluntary, non-remunerated blood donors from low-risk populations. (sbtcup.org)
- Despite this notion, family/replacement donors still provide more than 45% of the blood collected in India. (sbtcup.org)
- Such donors are supposed to be associated with a significantly higher prevalence of transfusion-transmissible infection (TTIs) including HIV, hepatitis B, hepatitis C, syphilis and malaria. (sbtcup.org)
- Thus, one of our key strategies to enhance blood safety is to focus on motivating non-remunerated blood donors and phasing out even replacement donors. (sbtcup.org)
- The key to recruiting and retaining safe blood donors is good epidemiological data on the prevalence (and incidence, where possible) of infectious markers in the general population to indentify low-risk donor populations coupled with an effective donor education, motivation and recruitment strategy to recruit new voluntary non-remunerated blood donors form these populations. (sbtcup.org)
- A pleasant environment in the blood bank, good donor care, polite and effective communication between staff and donors are all important factors for the retention of blood donors. (sbtcup.org)
- A guideline designed to assist those responsible for blood donor recruitment and implement a programme to improve communication with blood donors has been developed. (sbtcup.org)
- National Blood Donor Week, which runs every year in June, and World Blood Donor Day on June 14 provide an opportunity to celebrate the generosity of blood donors and raise awareness of the importance of giving blood, especially during the critical summer months when a shortage of blood products often occurs. (uniprix.com)
- To ensure the safety of both donors and recipients, a person may be excluded from giving blood, either temporarily or permanently. (uniprix.com)
- therefore, people with type o blood are known as "universal donors," and those with type ab blood are known as "universal recipients. (nypress.com)
- We collected data from allogeneic blood donors making whole blood and blood component donations during calendar years 2006 through 2008. (pubmedcentralcanada.ca)
- A TRALI mitigation policy that would not allow plasma from female whole blood donors to be prepared into transfusable plasma components would result in nearly a 50% reduction in the units of whole blood available for plasma manufacturing and would decrease the number of type AB plasma units that could be made from whole blood donations by the same amount. (pubmedcentralcanada.ca)
- 2 The AABB issued an association bulletin on TRALI mitigation in November 2006 recommending that member blood centers minimize the preparation of high-plasma-volume components from donors known to be white blood cell (WBC) alloimmunized or at increased risk for WBC alloimmunization. (pubmedcentralcanada.ca)
- In response to these recommendations, many blood collection agencies have restricted the distribution of plasma for transfusion to plasma that is derived from male donors as much as possible, with diversion of plasma from female donors to recovered plasma for use in manufacturing derivatives. (pubmedcentralcanada.ca)
- While this approach is practical for blood group A and O plasma products, it might be more difficult to collect sufficient group B and AB plasma products exclusively from male donors to support the need for transfusable plasma. (pubmedcentralcanada.ca)
- In response to the need for data on the prevalence of WBC alloimmunization in blood donors, the National Institutes of Health-funded Retrovirus Epidemiology Donor Study-II (REDS-II) initiated an investigation of the prevalence of antibodies to human leukocyte antigens (HLA) and/or human neutrophil antigens (HNA) among blood donors from six geographically dispersed US blood collection centers. (pubmedcentralcanada.ca)
- This may avoid the use of bank blood from unknown donors and significantly reduces the risk of acquiring transmitted diseases. (metaglossary.com)
- Nonimmunological transfusion reactions include cardiovascular overload, hypocalcemic tetany from citrate (used as the anticoagulant) overload, and disease transmission. (thefreedictionary.com)
- Allergic reactions are caused by the release of histamine by mast cells, a type of white blood cell. (hcvadvocate.org)
- The leucocytes present in donated blood play no therapeutic role in transfusion and may be a cause of adverse transfusion reactions. (transfusion.com.au)
- FNHTR are caused not only by leucocyte antigen-antibody reactions but also by the cytokines produced by leucocytes in the transfused blood component. (transfusion.com.au)
- Since Australia introduced pre-release bacterial screening in early 2008, septic transfusion reactions have greatly declined. (mja.com.au)
- They investigated the function of frozen monocytes when challenged by red blood cells that were exposed to three different antibodies previously implicated in transfusion-associated immune reactions in recipients. (blood.ca)
- Canadian Blood Services to, Blood Transfusions, Blood Alternatives and Transfusion Reactions A Guide to Transfusion Medicine blood alternatives and transfusion. (lunariusgraphics.com)
- These antibodies, with repeated transfusions, may also increase a recipient's risk of reactions to subsequent transfusions. (medcentral.org)
- If you have many blood transfusions, you are more likely to have problems from immune system reactions. (uwhealth.org)
- Caution and careful evaluation of the need for a blood transfusion is the rule, however, because of the risk for transfusion reactions and the transmission of viral diseases, particularly hepatitis. (lubopitko-bg.com)
- THE impetus for the development of transfusion-sparing pharmaceuticals or techniques has been the risks associated with transfusion (infectious disease, transfusion-associated lung injury, transfusion reactions [hemolytic, anaphylactic], immunomodulation) and the need for augmenting oxygen delivery when compatible blood is not available or cannot be used. (asahq.org)
- Antibodies to high-incidence red blood cell antigens should be considered if panagglutination reactions are noted in all panel cells, and negative reactions to autologous red blood cells are detected on antibody screening and identification tests. (bvsalud.org)
- Autologous transfusions are often considered before surgery to reduce the risk of blood-borne infections and transfusion reactions. (elitecme.com)
- Analyze the clinical and immunohematologic aspects of transfusion reactions and develop a plan for management and prevention of further transfusion reactions. (docplayer.net)
- Order necessary tests, record procedure in progress notes, order necessary replacement fluids and components, necessary pharmaceutical therapy, and direct treatment of reactions. (docplayer.net)
- 1. The collection of a patient's own blood before surgery, to be used if the patient needs a transfusion during or after the surgery, to reduce the possibility of needing banked blood, and with it the risk of having a transfusion reaction or contracting a transmissible infection. (thefreedictionary.com)
- Certain medical procedures involving blood fractions or that use a patient's own blood during the course of a medical procedure, such as hemodilution or cell salvage, are a matter of personal choice, according to what a person's conscience permits. (wikipedia.org)
- Epidural Blood Patch, consisting of a small amount of the patient's blood injected into the membrane surrounding the spinal cord. (wikipedia.org)
- PRP application techniques in musculoskeletal medicine utilize the concentrated healing components of a patient's own blood-reintroduced into a specific site-to regenerate tissue and speed the healing process. (practicalpainmanagement.com)
- This assay predicts the clinical significance of a patient's antibodies - that is, the likelihood that the patient's antibodies will cause the destruction of the transfused red cells and a serious transfusion reaction. (blood.ca)
- This number indicates whether the patient's antibodies reacted with the red blood cells, and thus whether the patient will have a serious transfusion reaction. (blood.ca)
- This unique and practical book introduces the reader to the concept of blood management and explains how to improve patient outcomes by avoiding undue blood loss, enhancing the patient's own blood, effective management of anemia and coagulopathy. (noblood.org)
- A treatment that uses healthy donor stem cells to restore a patient's marrow and blood cells. (lls.org)
- A donor who gives blood when it is required by a member of the patient's family or community. (sbtcup.org)
- 5 Recently, a more detailed analysis concluded that for ANH to be efficacious (conserve at least one unit of erythrocytes), surgical blood loss should be more than approximately 70% of the patient's blood volume. (asahq.org)
- Their findings are in accord with the prediction that more than 70% of a patient's blood volume must be lost for ANH to be efficacious, 6 and that there is a range of blood loss, above and below which ANH will not result in avoidance of allogeneic transfusion. (asahq.org)
- To confirm the patient's p phenotype, polymerase chain reaction and sequencing of the A4GALT gene were performed on her blood sample. (bvsalud.org)
- The patient's own blood. (metaglossary.com)
- This lecture covers in detail the advantages and disadvantages of autologous blood transfusions (ABT), including videos that demonstrate step-by-step instructions on how to perform ABTs, as well as indications and complications associated with ABT. (veccs.org)
- These components are administered individually as indicated to minimize unnecessary complications in our most critically ill patients. (veccs.org)
- Complications such as bradykinin-associated hypotension and transfusion related 'red eye' syndrome have been reported with particular types of filters used at the bedside. (transfusion.com.au)
- It is one of the most serious transfusion complications. (lymphedemapeople.com)
- The objective of this large population-based follow-up study was to determine whether allogeneic red blood cell transfusion was associated with increased odds of complications following THR. (biomedcentral.com)
- Therefore, perioperative infusion therapy should avoid these complications by replacing blood and fluid losses as timely and adequately as possible. (biomedcentral.com)
- After observing the negative effects of using allogenic blood transfusions, surgeons gradually adopt the auto-transfusion system in a bid to eliminate complications and the spread of diseases through cardiac surgeries. (openpr.com)
- This comprehensive booklet has been prepared jointly by the American Red Cross, the American Association of Blood Banks and America's Blood Centers to provide information about blood and blood products, donor testing, dose and administration, transfusion complications and contraindications. (wakehealth.edu)
- A subsequent hypothesis proposed that, if allogeneic blood transfusion causes immunosuppression, then recipients of perioperative allogeneic blood transfusion could be at increased risk for postoperative bacterial infection. (bloodjournal.org)
- Since 1981, more than 150 clinical studies have examined the association of perioperative allogeneic blood transfusion with cancer recurrence and/or postoperative bacterial infection. (bloodjournal.org)
- Both the earlier observational cohort studies and the recent RCTs have produced contradictory findings, and-because of the discrepancies among the published studies-the long-standing hypothesis of the potentially deleterious immunomodulatory effect of perioperative allogeneic blood transfusion remains unresolved. (bloodjournal.org)
- Background: The majority of allogeneic transfusions occur in the perioperative setting, especially during cardiac surgery. (elsevier.com)
- The secondary objectives included the need for perioperative blood transfusions during the procedure and in the intensive care unit. (elsevier.com)
- Other data collected included ANH volume, length of storage, and the quantity of all blood products given throughout the perioperative period. (elsevier.com)
- The Cell Saver 5+ system can help you realize potential cost savings by virtually eliminating unnecessary allogeneic transfusions and the associated risks of infection by returning fresh, high-quality blood throughout the perioperative care continuum. (haemonetics.com)
- When your platelet count drops below a certain level, you will be scheduled to have a platelet transfusion as part of your standard care. (knowcancer.com)
- You will then be randomly assigned (as in the toss of a coin) to either receive the standard platelet transfusion or a ThromboSol-preserved autologous platelet transfusion. (knowcancer.com)
- These procedures will be repeated each time you require a platelet transfusion. (knowcancer.com)
- Each time you receive an additional platelet transfusion, you will be assigned the group different from the one before. (knowcancer.com)
- Work done in collaboration with Dr. Rick Phipps's laboratory has shown that stored platelet transfusion supernatant promotes cellular secretion of PGE2 , IL6 and IL8 in vitro through a soluble CD40L dependent mechanism. (rochester.edu)
- Whole blood and blood components are used in various ways to meet the clinical needs of recipients. (surgeryencyclopedia.com)
- Pre-transfusion testing and issuance of blood and components to the recipients is performed by a transfusion service, which is commonly provided or supervised by a hospital blood bank. (surgeryencyclopedia.com)
- Blood transfusions are known to be broadly immunomodulatory and are associated with substantially poorer clinical outcomes in surgical and cancer patients, and better outcomes in solid organ allograft recipients. (rochester.edu)
- In their seminal study, Opelz et al 1 provided evidence, counterintuitive at the time, that recipients of allogeneic blood transfusion had improved renal allograft survival. (bloodjournal.org)
- On the basis of the immunomodulatory effect of allogeneic blood transfusion in renal allograft recipients, Gantt 14 raised the question in 1981 whether the TRIM effect might also be associated with an increased risk of cancer recurrence in patients undergoing resection of a malignancy. (bloodjournal.org)
- People who have type AB blood are called "universal recipients" because they can safely receive any type of blood. (kidshealth.org)
- Patient-specific femoral and tibial cutting blocks produced with use of data from preoperative computed tomography (CT) or magnetic resonance imaging (MRI) scans have been employed recently to optimize component alignment in total knee arthroplasty. (stanford.edu)
- Preoperative banking of the blood of patients planning total hip replacement is considered when possible. (medicinenet.com)
- In an emergency, blood cells and antibodies carried in the blood are brought to a point of infection, or blood-clotting substances are carried to a break in a blood vessel. (thefreedictionary.com)
- Coursework emphasizes the theory, practice and diagnostic principles in antibodies and red cell and tissue antigens related to transfusion medicine. (wcahospital.org)
- Screening for any unexpected red blood cell antibodies. (uhhospitals.org)
- These cells contain antibodies that can cause fevers in the person getting the transfusion. (uhhospitals.org)
- Agglutination - The clumping together of red cells in blood as a result of antibodies attaching to antigens on the surface of the cells. (lymphedemapeople.com)
- Antiserum - Human Blood serum containing antibodies that are specific for one or more antigens. (lymphedemapeople.com)
- Red blood cells are mixed with antibodies from a patient and added to the monocytes. (blood.ca)
- This 114-page report provides assessments of such technologies as molecular diagnostics, monoclonal and polyclonal antibodies, immunoassays, microtitration plates, IT, lasers, synthetic red cell substitutes, genetically engineered blood components, blood preservation, autologous blood transfusion/freezing and their potential applications for transfusion diagnostic. (researchandmarkets.com)
- Leukocyte-reduced blood" has been filtered to remove the white blood cells which contain antibodies that can cause fevers in the recipient of the transfusion. (medcentral.org)
- Therefore, additional research is needed on rare blood group antibodies and high-prevalence antigens, including anti-PP₁P(k) cases. (bvsalud.org)
- For the patients who have antibodies to high-incidence red cell antigens, it should be discussed to set up a national reference laboratory to quickly identify antibody specificities, and to consider establishing rare blood donor registry and frozen rare blood storage/supply system. (bvsalud.org)
- This article reviews characteristics of antibodies to high-incidence antigens found in Koreans and also the transfusion experiences of those patients based on literature. (bvsalud.org)
- If the patient has not been pregnant/transfused blood within 3 months and does not have history of antibodies and a negative antibody screen, the patient qualifies for delayed crossmatch. (wakehealth.edu)
- If patient has antibodies, the blood bank will have at least 2 units of blood available antigen negative or whatever the order specifies. (wakehealth.edu)
Aspects of transfusion1
- Also referred to as homologous Blood. (lymphedemapeople.com)
- in 1987 as an autologous transfusion component after an open heart operation to avoid homologous blood product transfusion. (practicalpainmanagement.com)
- It is a strategy to avoid exposure of patients to the potential hazards of homologous blood transfusions. (wikipedia.org)
- While the foregoing method may be used in a homologous blood system where the recipient is not the donor, it is especially suited for use in an autologous blood system where the blood is reinfused in the person who furnished the blood, and the identification on the bag assures the recipient that he/she is receiving his/her own blood. (google.es)
Collection and reinfusion1
- Specialists in blood bank technology perform both routine and specialized tests in blood bank immunohematology and perform transfusion services. (thefreedictionary.com)
- The laboratory provides a full array of blood components for transfusion support and an extended menu of immunohematology tests. (wakehealth.edu)
- Integrate the diagnostic test results of patients with immunohematology problems and develop a plan to further identify the antibody present and recommend the blood that would be needed for transfusion. (docplayer.net)
- Unfortunately, even after PAD, allogenic blood transfusion is not always avoided. (fujita-hu.ac.jp)
- Results: Allogenic blood transfusion was avoided during and after surgery in 107 patients (75%), whereas 36 patients required an allogenic transfusion (4.1 ± 3.8 U of packed red cells, 3.4 ± 4.1 U of fresh frozen plasma, and 5.8 ± 11.0 U of platelet concentrate). (fujita-hu.ac.jp)
Recombinant human erythropoietin1
- This is a type of white blood cell that helps fight infection. (uhhospitals.org)
- While historically the focus has been on prevention of transfusion-transmitted infection, other major hazards have been highlighted through haemovigilance programs. (mja.com.au)
- The number of neutrophils (a type of white blood cell that fights infection) that are identified in the blood count. (lls.org)
- This helps with treating anemia symptoms, and improving infection control and blood clotting. (memorialhospitaljax.com)
- Once the procedure is done, the recipient is isolated to reduce the chance of infection while the healthy stem cells repopulate the blood cell count. (memorialhospitaljax.com)
- Leal-Noval SR, Rincon-Ferrari MD, Garcia-Curiel A, Herruzo-Aviles A, Camacho-Larana P, Garnacho-Montero J, Amaya-Villar R (2001) Transfusion of blood components and postoperative infection in patients undergoing cardiac surgery. (springer.com)
- white blood cells - help to fight infection, and aid in the immune process. (medcentral.org)
- White blood cells are part of the immune system, and its main defense against infection. (kidshealth.org)
- IT is well known that general and local infection continues to be one of the main causes of morbidity and mortality associated with orthopedic and trauma surgery, with a higher incidence in patients receiving allogeneic blood transfusions (ABTs). (asahq.org)
- 1 Unilateral total knee replacement (TKR) can result in a substantial blood loss, 2,3 and 20-50% of these patients receive ABTs, which may increase the risk of postoperative infection. (asahq.org)
Accept blood transfusions1
- Antibody - Proteins that react with antigens on red Blood cells and may destroy transfused red Blood cells. (lymphedemapeople.com)
- Prevention of alloimmunization to red blood cell, platelet and leukocyte antigens. (redcrossblood.org)
- Allogeneic blood transfusion results in the infusion into the recipient of large amounts of foreign antigens in both soluble and cell-associated forms. (bloodjournal.org)
- This comprehensive seven-country report is designed to help current suppliers and potential market entrants identify and evaluate emerging opportunities in the global transfusion diagnostics market during the next ten years, and assist industry executives in developing effective business, new product development and marketing strategies. (bio-medicine.org)
- Assessment of current and emerging technologies, and their potential applications for the transfusion diagnostics market. (bio-medicine.org)
Morbidity and morta2
- In addition to the economic implications, there is emerging evidence that blood transfusion may increase both morbidity and mortality. (elsevier.com)
- Scott BH, Seifert FC, Grimson R (2008) Blood transfusion is associated with increased resource utilization, morbidity and mortality in cardiac surgery. (springer.com)
- Zurück zum Zitat Boralessa H, Goldhill DR, Tucker K, Mortimer AJ, Grant-Casey J (2009) National comparative audit of blood use in elective primary unilateral total hip replacement surgery in the UK. (springermedizin.de)
- People preparing for elective surgery may have their blood collected and held, and then returned to them if needed during their surgery. (surgeryencyclopedia.com)
- We investigated the predictors of blood component usage during elective cardiac surgery in patients prepared with PAD. (fujita-hu.ac.jp)
- A person can donate his or her own blood before undergoing elective (planned) surgery to be used during surgery if needed. (lubopitko-bg.com)
- This technique is often used prior to elective surgery if blood loss is expected to occur. (metaglossary.com)
- Exclusive or supplemental use of autologous Blood can eliminate or reduce adverse effects of transfusion. (lymphedemapeople.com)
- Participation in these systems is voluntary, but NSQHS Standards mandate that hospitals have systems in place for recognising and reporting transfusion-related incidents and adverse events. (mja.com.au)
- Estimates of infectious and non-infectious hazards are reported periodically by the Australian Red Cross Blood Service ( http://www.transfusion.com.au/adverse_events/risks/estimates ). (mja.com.au)
- Red blood cell transfusion was associated with an adverse prognosis following primary THR, in particular with increased odds of death and pneumonia. (biomedcentral.com)
- Most commonly, there is an immune-mediated hemolysis involving alloantibodies, which may be naturally occurring or the result of an earlier transfusion, in the recipient's serum and the donor's erythrocytes. (thefreedictionary.com)
- Albumin, immune globulins, and clotting-factors may also be separated and processed for transfusions. (uhhospitals.org)
- Plasma separated from the cellular elements is usually further separated by chemical means into various components, such as plasma protein fraction, serum albumin, immune serum, and clotting factors. (lubopitko-bg.com)
- It also carries other components that support the body's immune system. (cancer.ca)
- In most health agencies the blood bank is located in the pathology laboratory. (thefreedictionary.com)
- Symptomatic patients may undergo a variety of pathology tests, which may include blood tests, and a bone marrow biopsy and aspirate . (northshore.org)
- The resident is expected to develop an assessment and plan for these problems and discuss these with the senior pathology resident on the blood bank senior rotation and with the guidance, positive feedback and training provided by the transfusion medicine service attending. (docplayer.net)
- Your doctor should discuss the potential risks, benefits and alternatives with you if you are being considered for transfusion, as part of an informed consent. (rochester.edu)
- His publications have appeared in The Lancet, the journal Transfusion, and Transfusion Alternatives in Transfusion Medicine, for which he serves in Editorial and Scientific Boards. (noblood.org)
- Exploring the Transfusion Alternatives. (slideserve.com)
- What are the transfusion alternatives? (slideserve.com)
- 19 BCSH Blood Transfusion Task Force , Boulton , F.E. & James , V. ( 2007 ) Guidelines for policies on alternatives to allogeneic blood transfusion. (rmmonline.co.uk)
- Although the risks of HIV and hepatitis transmission have diminished, haemovigilance programs highlight that other significant transfusion hazards remain. (mja.com.au)
- Additionally, propensity score analysis suggested possible associations of RBC transfusion with increased risks for composite morbidity outcome and in-hospital mortality, renal morbidity, pneumonia, and mediastinitis. (springer.com)
- The theory and practice of measuring these constituents in human blood and body fluids using manual and automated methods. (wcahospital.org)
- Although these and other initiatives contribute to safer transfusion, avoidance of unnecessary transfusion is essential to ensuring safe transfusion practice. (mja.com.au)
- The quality and safety of the U.S. blood supply is governed by physician-established guidelines for the practice of blood banking as found in the Standards of the American Association of Blood Banks (AABB) and through the organization's inspection and accreditation program. (surgeryencyclopedia.com)
- Conversely, the standard practice of blood banks is to deliver the oldest RBC unit in order to decrease blood wastage. (clinicaltrials.gov)
- This procedure is similar to donating plasma to a blood bank. (knowcancer.com)
- It is normal procedure to test the recipient and give blood of the same type. (lubopitko-bg.com)
- People with cancer may donate their own blood in case they need a blood transfusion during or after surgery or an invasive procedure. (cancer.ca)
- Your own blood is returned to you after surgery. (rochester.edu)
- But you may also donate blood several weeks before having surgery. (uhhospitals.org)
- Blood replacement may be needed by people who have lost blood through accidents, burns, hemorrhage, or surgery. (surgeryencyclopedia.com)
- Vamvakas E, Carven J (2000) RBC transfusion and postoperative length of stay in the hospital or the intensive care unit among patients undergoing coronary artery bypass graft surgery: the effects of confounding factors. (springer.com)
- During surgery, blood is diverted to bags and replaced with a nonblood volume expander. (sabm.org)
- Blood transfusion is a medical treatment that replaces blood lost through injury, surgery, or disease. (uwhealth.org)
- Some people bank their own blood a few weeks before they have surgery. (uwhealth.org)
- If they need a transfusion during surgery, they can receive their own banked blood. (uwhealth.org)
- Blood Transfusions: Should I Bank Blood Before Surgery? (uwhealth.org)
- Such autologous (self-originating) blood is stored in a blood bank only until the surgery is completed. (lubopitko-bg.com)
- 3 The basis of this notion is that ANH reduces the circulating concentration of erythrocytes, thus, following ANH, the blood lost during surgery contains a lesser concentration of erythrocytes than if ANH had not been performed, resulting in a conservation of erythrocytes. (asahq.org)
- Some people may need blood if they have anemia or lose blood after surgery. (cancer.ca)
- If your blood isn't needed during or after surgery, it is thrown away. (cancer.ca)
- Autologous blood is usually collected a few weeks before surgery. (cancer.ca)
- Patients should deposit their blood up to 6 weeks prior to surgery. (elitecme.com)
- Patients should complete all autologous donations approximately one week prior to their scheduled surgery date. (wakehealth.edu)
- No other blood specimen is necessary for blood bank on day of surgery. (wakehealth.edu)
- blood that is collected from a person to use in later transfusions to that same person during surgery. (metaglossary.com)
- Topics include blood group systems, hemolytic diseases, blood donor and autologous transfusion practices. (wcahospital.org)
- The blood is also tested for infectious diseases. (uhhospitals.org)
- These components prevent the transmission of transfusion-related blood-borne diseases in patients, and they also provide more compatible blood than in the case of autologous blood transfusions. (marketsandmarkets.com)
- This segment is estimated to grow at the highest rate during the forecast period due to the high prevalence of cardiac diseases and recommendations for autologous transfusion (by entities such as the WHO) during cardiac surgeries. (marketsandmarkets.com)
- Blood banking includes typing the blood for transfusion and testing for infectious diseases. (medcentral.org)
- Donated blood is then carefully tested for certain diseases and to find out the blood type. (uwhealth.org)
- Some people worry about getting diseases from infected blood, but the United States has one of the safest blood supplies in the world. (kidshealth.org)
- Several conditions and diseases may mean a person can't donate blood, including a diagnosis or history of certain cancers. (cancer.ca)
- Sales and market share estimates for leading suppliers of blood typing, grouping and infectious disease screening tests by country and individual product. (aarkstore.com)
- Analysis of current and emerging molecular blood typing, grouping and infectious disease NAT screening assays. (aarkstore.com)
- New product development opportunities for molecular blood typing, grouping and infectious disease NAT assays and instrumentation with significant market appeal. (aarkstore.com)