A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
A complex of ferric oxyhydroxide with dextrans of 5000 to 7000 daltons in a viscous solution containing 50 mg/ml of iron. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.
Used as a support for ion-exchange chromatography.
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
A genus of gram-positive, facultatively anaerobic bacteria whose growth is dependent on the presence of a fermentable carbohydrate. It is nonpathogenic to plants and animals, including humans.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.
Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.
Abnormal accumulation of fluid in tissues of any part of the LARYNX, commonly associated with laryngeal injuries and allergic reactions.
Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.
A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration.
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.
The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.
Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
A sucrose polymer of high molecular weight.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The sum of the weight of all the atoms in a molecule.
A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.
A publication issued at stated, more or less regular, intervals.
A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
Exclusive legal rights or privileges applied to inventions, plants, etc.
Polymers synthesized by living organisms. They play a role in the formation of macromolecular structures and are synthesized via the covalent linkage of biological molecules, especially AMINO ACIDS; NUCLEOTIDES; and CARBOHYDRATES.
The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.
Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.
Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.
Intracellular step that follows VIRUS INTERNALIZATION during which the viral nucleic acid and CAPSID are separated.
The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.
Cellular uptake of extracellular materials within membrane-limited vacuoles or microvesicles. ENDOSOMES play a central role in endocytosis.
Spontaneous tearing of the membranes surrounding the FETUS any time before the onset of OBSTETRIC LABOR. Preterm PROM is membrane rupture before 37 weeks of GESTATION.
A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Vesicles formed when cell-membrane coated pits (COATED PITS, CELL-MEMBRANE) invaginate and pinch off. The outer surface of these vesicles is covered with a lattice-like network of the protein CLATHRIN. Shortly after formation, however, the clathrin coat is removed and the vesicles are referred to as ENDOSOMES.
The entering of cells by viruses following VIRUS ATTACHMENT. This is achieved by ENDOCYTOSIS, by direct MEMBRANE FUSION of the viral membrane with the CELL MEMBRANE, or by translocation of the whole virus across the cell membrane.
Group composed of associates of same species, approximately the same age, and usually of similar rank or social status.
A form of interactive entertainment in which the player controls electronically generated images that appear on a video display screen. This includes video games played in the home on special machines or home computers, and those played in arcades.
Recording of visual and sometimes sound signals on magnetic tape.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.
... is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. ... Dextran also increases blood sugar levels.[citation needed] Dextran can be used in an ATPS for PEGylation Dextran is used in ... Resource on dextran properties and structure of dextran polymers Dextrans at the US National Library of Medicine Medical ... with branches from α-1,3 linkages. This characteristic branching distinguishes a dextran from a dextrin, which is a straight ...
Dendrimer is a class of highly branched molecules based on various building blocks and synthesized through a convergent or a ... Another method is the use of cationic polymers such as DEAE-dextran or polyethylenimine (PEI). The negatively charged DNA binds ... Then, application of magnetic force drives the nucleic acid particle complexes towards and into the target cells, where the ... This transfection technology performs the same tasks as other biochemical procedures utilizing polymers, DEAE-dextran, calcium ...
... deae-dextran MeSH D09.698.365.272.300 - dextran sulfate MeSH D09.698.365.272.400 - iron-dextran complex MeSH D09.698.365.388 - ... branched-chain MeSH D09.698.629.802 - trisaccharides MeSH D09.698.629.802.100 - acarbose MeSH D09.698.629.802.700 - raffinose ...
Glycogen is composed of a branched chain of glucose residues. It is stored in liver and muscles. It is an energy reserve for ... Polysaccharides also play an important role in formation of biofilms and the structuring of complex life forms in bacteria like ... Humans have developed some of these polysaccharides into useful products, including xanthan gum, dextran, welan gum, gellan gum ... Glycogen is a polymer of α(1→4) glycosidic bonds linked, with α(1→6)-linked branches. Glycogen is found in the form of granules ...
... and reversible complexes. The formation of these complexes involves the participation of common molecular forces such as the ... Cellulose and dextran ion exchangers possess larger pore sizes and low charge densities making them suitable for protein ... Branched chain compounds elute more rapidly than their corresponding linear isomers because the overall surface area is ... cellulose and dextran ion exchangers (gels), and controlled-pore glass or porous silica. Polystyrene resins allow cross linkage ...
Comparison of filamin A- induced crosslinking and Arp2/3 complex-mediated branching on the mechanics of actin filaments. J Biol ... Solubilization of C3 fragments deposited on crosslinked dextran gel beads. Clin Immunol Immunopathol. 1979; 14:384- 394. 50. ... Arp2/3 Complex-Deficient Mouse Fibroblasts are Viable and Have Normal Leading Edge Actin Structure and Function. 2005. Proc Nat ... Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells. J Cell Biol ...
By using pseudorabies viruses with different fluorescent reporters, dual infection models can parse complex synaptic ... and branch repeatedly to innervate every part of the body. Nerves are made primarily of the axons or dendrites of neurons ( ... dextrans) that are more or less avidly absorbed by neurons or their processes. These molecules are selectively transported ... allowing researchers to trace their paths up to their thinnest terminal branches in a slice of nervous tissue, thanks to the ...
The ion complexes the olefins make with silver ions are weak and made based on the overlapping of pi, sigma, and d orbitals and ... Agarose gel based medium contain large pores as well but their substitution ability is lower in comparison to dextrans. The ... Since 1975 ion chromatography has been widely used in many branches of industry. The main beneficial advantages are reliability ... Counterions such as copper (II) are chosen most often for effectively separating peptides and amino acids through complex ...
Blue dextran is not recommended for Vo determination because it is heterogeneous and may give variable results) The elution ... It is usually applied to large molecules or macromolecular complexes such as proteins and industrial polymers. Typically, when ... and the same is true of branched polymers which elute late compared to linear reference standards with the same molar mass. ... While Lathe and Ruthven used starch gels as the matrix, Jerker Porath and Per Flodin later introduced dextran gels; other gels ...
S. mutans produces dextran via the enzyme dextransucrase (a hexosyltransferase) using sucrose as a substrate in the following ... Conditions in the oral cavity are diverse and complex, frequently changing from one extreme to another. Thus, to survive in the ... eds.). Baron's Medical Microbiology (4th ed.). University of Texas Medical Branch. ISBN 978-0-9631172-1-2. PMID 21413316. ... Biswas S, Biswas I (April 2011). "Role of VltAB, an ABC transporter complex, in viologen tolerance in Streptococcus mutans". ...
... s are a class of nanostructure composed of protein-polymer conjugates (i.e. complexes composed of one ... Using branched carbohydrates can give unique biological properties while maintaining molecular definition. Although covalent ... dextran derivative conjugate". Journal of Chromatography B: Biomedical Sciences and Applications. 761 (2): 247-254. doi:10.1016 ... Thermoresponsive conjugates have been exploited for the subsequent separation of proteins from a complex mixture. This method ...
Dextran is a polysaccharide derived from bacteria; it is usually produced by enzymes from certain strains of leuconostoc or ... Crystalline matrices such as the aragonite mentioned here are allowed for the promotion of a complex 3D tissue formation that ... The number of neurites per cell was constrained by the ridges and grooves, producing bipolar rather than branching phenotypes. ... Cross-linked dextran hydrogel beads have been widely used as low protein-binding matrices for column chromatography ...
... branched-dextran exo-1,2-a-glucosidase EC 3.2.1.116: glucan 1,4-a-maltotriohydrolase EC 3.2.1.117: amygdalin b-glucosidase EC ... Now included with EC 3.4.22.53 (calpain-2) and EC 3.4.25.1 (proteasome endopeptidase complex) EC 3.4.24.6: leucolysin EC 3.4. ... Now EC 3.4.25.1, proteasome endopeptidase complex EC 3.5.1.1: asparaginase EC 3.5.1.2: glutaminase EC 3.5.1.3: omega-amidase EC ... Now EC 3.4.24.56, insulysin EC 3.4.99.46: Transferred entry: multicatalytic endopeptidase complex. ...
UMPS is subject to complex regulation by OMP, the product of its OPRTase and the substrate for the ODCase. OMP is an allosteric ... have occurred distinctly in different branches of the tree of life. For one thing, even though OPRTase is found at the N- ... phosphoribosyl-a-pyrophosphate on de novo pyrimidine biosynthesis in cultured Ehrlich ascites cells made permeable with dextran ... There is a 30:1 equilibrium between the close and open structures in the enzyme-Mg-PRPP complex, which suggests that the close ...
... and are very complex macromolecules. They also play a fundamental role in the structure and function of cells.[11] Consisting ... Such polysaccharides include pectin, dextran, agar, and xanthan. Sugar content is commonly measured in degrees brix. ... Branches of chemistry. *Glossary of chemical formulas. *List of biomolecules. *List of inorganic compounds ...
After 51 days, on April 19, 1993, FBI agents ended a standoff with the Branch Davidians by setting a fire which engulfed their ... Downtown Waco is home to Magnolia Market, a shopping complex containing specialty stores, food trucks, and event space, set in ... Allene Jeanes (1906-1995), a chemical engineer whose work included the development of Dextran and Xanthan gum, was born in Waco ... On February 28, 1993, a shootout occurred in which six Branch Davidians and four agents of the United States Bureau of Alcohol ...
complex carbohydrates, such as long-chained sugars also called starch, oligosaccharides, or polysaccharides, are sources of ... The variables include chemical structure, polymer concentration, molecular weight, degree of chain branching, the extent of ... Immobilizing of nutrients and other chemicals within complex polysaccharide molecules affects their release and subsequent ... has been used as a collective term for a complex mixture of substances with different chemical and physical properties which ...
The ion complexes the olefins make with silver ions are weak and made based on the overlapping of pi, sigma, and d orbitals and ... Agarose gel based medium contain large pores as well but their substitution ability is lower in comparison to dextrans. The ... Since 1975 ion chromatography has been widely used in many branches of industry. The main beneficial advantages are reliability ... Counterions such as copper (II) are chosen most often for effectively separating peptides and amino acids through complex ...
... of all the dextrans. Complex dextrans (higher-molecular-mass and/or highly branched), showing slower fermentation and gas ... All dextrans tested reached peak gas production rates at 9 h, except linear 1-kDa dextran and branched 70-kDa dextran + 37% α-1 ... dextran at 6 kDa, dextran at 6 kDa with 33% α-1,2 linkages (6 kDa dextran + 33% α-1,2; molecular mass, 9,000 Da), dextran at 70 ... 1-kDa dextran (unbranched) , 70-kDa dextran (unbranched) , 6-kDa dextran (unbranched), with linear 1-kDa dextran producing the ...
Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. ... Dextran also increases blood sugar levels.[citation needed] Dextran can be used in an ATPS for PEGylation Dextran is used in ... Resource on dextran properties and structure of dextran polymers Dextrans at the US National Library of Medicine Medical ... with branches from α-1,3 linkages. This characteristic branching distinguishes a dextran from a dextrin, which is a straight ...
Dextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons. It is produced from certain bacteria ... and this activity is used commercially to obtain dextran.Dextran 40 is a sterile, nonpyrogenic preparation of low molecular ... The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. ... The chains can be composed of about 200,000 glucose units.Many bacteria, like Leuconostoc, can synthesize dextran from sucrose ...
Dextran, 250,000, Powder DE130 , 9004-54-0 , Spectrum Chemical Dextran, 250,000, Powder is a complex branched glucan that is ... Dextran, 4,000, Powder D1179 , 9004-54-0 , Spectrum Chemical Dextran, 4,000, Powder is a complex branched glucan that is ... Dextran, 40,000, Powder DE124 , 9004-54-0 , Spectrum Chemical Dextran, 40,000, Powder is a complex branched glucan that is ... Dextran, 500,000, Powder D1004 , 9004-54-0 , Spectrum Chemical Dextran, 500,000, Powder is a complex branched glucan that is ...
Dextran Market 2018, Forecast to 2023 is a market research report available at US $4880 for a Single User PDF License from RnR ... Dextran is a complex branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths. It ... 1.1 Dextran Introduction. 1.2 Market Analysis by Type. 1.2.1 Dextran 20. 1.2.2 Dextran 40. 1.2.3 Dextran 60. 1.2.4 Dextran 70. ... Table Major Manufacturers of Dextran 20. Figure Dextran 40 Picture. Table Major Manufacturers of Dextran 40. Figure Dextran 60 ...
Dextrans are complex, branched polysaccharides consisting of chains of individual glucose units, and are synthesised from ... It is hypothesised that dextrans may form water-soluble complexes with LAs that remain at the site of injection longer than the ... but it is hypothesised that dextrans may form water-soluble complexes with LAs that remain at the site of injection longer than ... in the duration of the block when compared with the dextran 110 mixture. The authors concluded that the use of dextran of ...
Several animal models have been used to study colitis and one such model involves the oral administration of dextran sulphate ... Dextran sulfate sodium (DSS) can be used to study colitis (inflammatory bowel disease) as well as an antiviral as agent. ... Dextran sulfate sodium salt, or DSS, is a branched glucan that triggers colitis in mice and rats when administered in drinking ... Dextran sulfate sodium is also used to precipitate lipoproteins and to release DNA from DNA-histone complexes. ...
Dextran is a complex, branched polysaccharide, which can be used for a variety of biomedical applications, including monitoring ... Permeation by dextran into cellular organelles is dependent on size. We used TRITC-dextran of 155 kDa, which is largely ... Coupling of the nucleus and cytoplasm: role of the LINC complex. J. Cell Biol. 172:41-53. [PMC free article] [PubMed] ... In all cases dextran is clearly seen in the nuclear region. The greatest accumulation is in the region of the nucleus next to ...
CONCLUSIONS: Biological samples of complex isobaric oligosaccharides can be analysed using IMMS in the negative mode providing ... of maltooligosaccharides treated with the potential anti-tuberculosis drug target Mycobacterium tuberculosis GlgB branching ... Discrimination of large maltooligosaccharides from isobaric dextran and pullulan using ion mobility mass spectrometry 30th ... Discrimination of large maltooligosaccharides from isobaric dextran and pullulan using ion mobility mass spectrometry ...
... the polymer can be branched like in dextran, the polymer can have a complex repeat like in xanthan. Descriptions of the polymer ... wherein R3 and R8 are independently selected from the group consisting of: H, linear or branched C1-C4 alkyl, CH2OH and ... wherein R3 and R8 are independently selected from the group consisting of: H, linear or branched C1-C4 alkyl, CH2OH and ... wherein R3 and R8 are independently selected from the group consisting of: H, linear or branched C1-C4 alkyl, CH2OH and ...
Dextran (High Molecular Weight Branched Chain Glucose Polymer) MyoHypertrophic Activating Complex Trimethylglycine, ... Amylopectin (Waxy Maize - High Molecular Weight Branched Chain Glucose Polymer), Maltodextrin (Glucose Polymer), Isomaltulose ( ...
Summary Dextran is a high molecular weight polymer of glucose... ... 76 Pages Report] Check for Discount on Global Dextran Market ... Dextran is a high molecular weight polymer of glucose which is a complex branched glucan (polysaccharide made of many glucose ... Fig Global Dextran Market Size and CAGR 2011-2017 (Value). Fig Global Dextran Market Size and CAGR 2011-2017 (Volume). Fig ... Global Dextran Market Data Survey Report 2025 Table of Contents. 1 Global Market Overview. 1.1 Scope of Statistics. 1.1.1 Scope ...
Dextran is a complex, branched glucan that enters cells through fluid-phase pinocytosis and accumulates following its ... For Figure 4E, the number of dextran+ compartments in each cell is plotted on the y-axis, and ranged from a mean of 14.0 (mock- ... Graphs display the number of dextran +compartments per cell (n = 7-10 cells per condition for a representative of three ... Endo-lysosomal vesicles positive for Rab7 and LAMP1 are terminal vesicles for the transport of dextran * WH Humphries ...
The 4th branch of the IX-X complex was drawn into a glass pipette using suction. aCSF was removed from the pipette using ... root of the IX-X cranial nerve complex.. (A) illustrates the tetramethylrhodamine-dextran (TRITC) backfill procedure. Orange ... and receives its innervation from the laryngeal branch of the vagus nerve that arises the fourth rootlet of the IX-X complex in ... Origin and identification of fibers in the cranial nerve IX-X complex of Xenopus laevis: Lucifer Yellow backfills in vitro * HB ...
Dendrimer is a class of highly branched molecules based on various building blocks and synthesized through a convergent or a ... Another method is the use of cationic polymers such as DEAE-dextran or polyethylenimine (PEI). The negatively charged DNA binds ... Then, application of magnetic force drives the nucleic acid particle complexes towards and into the target cells, where the ... This transfection technology performs the same tasks as other biochemical procedures utilizing polymers, DEAE-dextran, calcium ...
After entering the GI tract wall, sympathetic axons branched extensively to form complex terminal arrays within the myenteric ... Sympathetic arbors also formed long rectilinear multiply branched arrays of neurites within the circular muscle and its ... Fischer 344 rats (N = 50) received injections of dextran biotin into the left celiac and superior mesenteric ganglia. Nine days ... Fischer 344 rats (N = 50) received injections of dextran biotin into the left celiac and superior mesenteric ganglia. Nine days ...
... dextran, etc.), a branched-chain polymer (see U.S. Pat. Nos. 4,289,872 and 5,229,490; PCT Publication No. WO 93/21259), a lipid ... Structurally, class I PI3Ks exist as heterodimeric complexes, consisting of a p110 catalytic subunit and a p55, p85, or p101 ... As used herein, the term "alkyl" is defined as straight chained and branched hydrocarbon groups containing the indicated number ... Also, the use of liposomes, microcapsules or microspheres, inclusion complexes, or other types of carriers is contemplated. ...
Defining the subcellular distribution of signaling complexes is imperative to understanding the output from that complex. ... We focus here on two parameters, dendritic tree size and branch point numbers, which can be rapidly and easily determined from ... Olivocerebellar neurons are labeled by anterograde tracing with a dextran-conjugated dye and then monitored by TPF imaging ... Wholemount Immunohistochemistry for Revealing Complex Brain Topography Authors: Joshua J. White, Stacey L. Reeber, Richard ...
This protocol describes how to perform TPF time-lapse imaging and laser nanosurgery of single axonal branches in the cerebellum ... Elucidating the mechanisms that coordinate firing in GnRH neurons is a complex problem. First, the GnRH neurons are relatively ... Olivocerebellar neurons are labeled by anterograde tracing with a dextran-conjugated dye and then monitored by TPF imaging ... The investigation of the time-lapse dynamics of degeneration and regeneration of these axons within their complex environment ...
It is well known that PF4 forms complexes with polyanions other than heparin, such as dextran sulfate, pentosan polysulfate, ... such as those that occur on branched polysaccharides.26 Nucleic acids express charged oxygens (O−) of phosphate groups that are ... PF4/aptamer complexes induce anti-PF4/polyanion antibodies in vivo. In mice, mPF4/44mer-DNA protein C aptamer complexes induced ... The PF4/44mer-DNA protein C aptamer complexes induced a strong immune response in mice, and these complexes are recognized by ...
2018-2023 Global Dextran Consumption Market Report is a market research report available at US $4660 for a Single User PDF ... Dextran is a complex branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths. It ... 2.2 Dextran Segment by Type. 2.2.1 Dextran 20. 2.2.2 Dextran 40. 2.2.3 Dextran 60. 2.2.4 Dextran 70. 2.2.5 Other. 2.3 Dextran ... 4 Dextran by Regions. 4.1 Dextran by Regions. 4.1.1 Global Dextran Consumption by Regions. 4.1.2 Global Dextran Value by ...
brevis culture were identified as dextrans with some 1-Gp-3 links in the main chain with a ratio [branched/total units] of 0.19 ... The grains or the matrix is formed through the effort of a symbiotic relationship shared among the complex microflora which ... SKG are small, transparent and firm mucilaginous masses, which consist of polysaccharides [dextrans] with chains made up of ... Formalin - fixed kefir grains examined under a microscope presented a protein/polysaccharide/lipid complex consisting mainly of ...
Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose. Source: https://en.wikipedia.org ...
Zone D: Random coil: dextran, pullulan. Zone E: Highly branched: amylopectin, glycogen ... The liganded amylose-iodine complex: rows of iodine atoms (shown in black) neatly fit into the core of the amylose helix. ... D-galacturonosyl sections containing branch-points with side chains (1 - 20 residues) of mainly L-arabinose and D-galactose ...
the Dextran biopolymer. The degree of branching is approximately 5. The branches are mostly 1-2 glucose units long. Dextran can ... complex heteropolysaccharide -low viscosity 50. Functional properties of carbohydrate. Food products Nonfood products. ... Dextran. Dextran is an a-D-1,6-glucose-linked glucan with side-chains 1-3 linked to the backbone units of ... Microbial xanthan, gellan, dextran Seaweed carrageenan, agar, alginate Plant gum arabic, guar gum, pectin, cellulose, starch, ...
Dextran is a complex branched polysaccharide composed of many glucose molecules with chains of varying lengths. It is ... "Biotechnology of Nucleic Acids Medicines as Gene Therapeutics and Their Drug Complexes". Chronicles of Pharmaceutical Science ... Furthermore, problems related to microorganism-based synthesis for nanoparticles also include the complex steps, such as ... this device would use tiny manipulators to position atoms and molecules to build an object as complex as a desktop computer. ...
... and dextran is a complex branched glucan used to reduce blood viscosity, decreasing vascular thrombosis by reducing erythrocyte ... Additionally, WMO-II contains adenosine, acetylcysteine and dextran for prevention of free radicals. Adenosine prevents tissue ...
... dextran, LPS, and immune complexes (5, 8, 9, 10, 11, 12). These Ags were trapped mainly in the marginal zone of the murine ... Weak fluorescence signals were detected in the red pulp, probably due to direct transport of Ag via small branches of the ... Cellular, but not humoral, systemic immune response against rabies virus immune stimulating complexes are macrophage dependent ... as well as for live pathogens with a more complex surface structure like Candida, Brucella, Lactobacillus, or vesicular ...
Dextrans are branched glucose polysaccharides synthesized by bacteria from sucrose solutions. Dextrans are primarily produced ... Arabinogalactans are complex, highly branched polymers of arabinose and galactose in the ratio of from about 1:3 to about 1:10 ... Dextrans are commercially available and are sold in various molecular weight ranges. Dextrans useful in the ophthalmic ... Dextrans are similar to glycogen and amylopectin, but differ therefrom in that the principle linkage between the anhydroglucose ...
... liquids or compounds as inclusion complexes so that the complex may be handled in solid form and the included constituent (such ... Contemplated cellulose derivatives and dextran derivatives include DEAE-cellulose, guanidinoethylcellulose, or DEAE-Sephadex. ... and branched cyclodextrin. As one skilled in the art will appreciate, any cyclodextrin or mixture of cyclodextrins, ... Formation of inclusion complexes using cyclodextrin or its derivatives protects the constituent (i.e., cysteamine compound) ...
  • Dextrans are complex, branched polysaccharides consisting of chains of individual glucose units, and are synthesised from sucrose by the action of certain lactic-acid bacteria. (ispub.com)
  • The particular polysaccharides useful in the ophthalmic solutions of the present invention are selected from dextrans and arabinogalactans. (justia.com)
  • Dextrans are branched glucose polysaccharides synthesized by bacteria from sucrose solutions. (justia.com)
  • This invention also relates to biosensor surfaces that have been blocked by monosaccharides, disaccharides (such as trehalose), polysaccharides (such as dextran), or oligosaccharides to prevent non-specific protein binding. (patentsencyclopedia.com)
  • Any of a group of branched polysaccharides with various molecular weights that are used to prevent thrombosis, as plasma volume expanders, and as food additives. (joycekillian.com)
  • Detailed studies on oxidation and reduction of complex polysaccharides were studied. (derpharmachemica.com)
  • Single-walled carbon nanotubes (SWCNTs) form complexes with amylose, amylopectin and other polysaccharides provided the latter are non-ionic as proven by Raman spectroscopy, rheological and thermal (TG/DTG and DSC) studies. (khachatryan.com)
  • in revised form: 26 June 2009 / Accepted: 1 July 2009 / Published: 13 July 2009 Abstract: Extracellular polymeric substances (EPS) produced by microorganisms are a complex mixture of biopolymers primarily consisting of polysaccharides, as well as proteins, nucleic acids, lipids and humic substances. (slideshare.net)
  • Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. (wikipedia.org)
  • Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. (drugbank.ca)
  • Dextran is a complex branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths. (rnrmarketresearch.com)
  • Dextran is a high molecular weight polymer of glucose which is a complex branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths (from 3 to 2000 kilo Daltons). (reportsnreports.com)
  • Market Overview Dextran is a high molecular weight polymer of glucose which is a complex branched glucan (polysaccharide. (diferentials.com)
  • Amylopectin is a water-soluble polysaccharide and highly branched polymer of α-glucose units found in plants. (unionpedia.org)
  • The translucent crystals which are formed from Dextran (A complex branched glucan or polysaccharide formed from many glucose molecules), make up the bulk of what you see as grains. (blogspot.com)
  • Numerical simulations carried out for SWCNTs with dextrans proved that enveloping polysaccharide chains around SWCNTs is not crucial for the complex formation. (khachatryan.com)
  • Dextran is a polysaccharide which is composed of alpha-1,6 linkage glucose unit. (prionsbiotech.com)
  • 7. The process according to claim 6 wherein the polysaccharide is branched. (google.es)
  • Dextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons. (drugbank.ca)
  • It is a complex branched glucan that is synthethized by certain lactic acid bacteria from sucrose. (spectrumchemical.com)
  • Dextran sulfate sodium salt, or DSS, is a branched glucan that triggers colitis in mice and rats when administered in drinking water. (mpbio.com)
  • Mushrooms have short beta-glucan linked branches coming off their backbone and mushroom myceliums are made from an indigestible fiber called 'chitin. (breakingmuscle.com)
  • Low molecular weight glucan like dextran has been oxidized using different quantities of sodium hypochlorite and the number of glucose units oxidized has been analyzed using potentiometric titrations. (derpharmachemica.com)
  • There are 15 Chapters to deeply display the global Dextran market. (rnrmarketresearch.com)
  • The global Dextran market will reach Volume Million USD in 2017 with CAGR xx% 2018-2025. (reportsnreports.com)
  • In this report, LP Information covers the present scenario (with the base year being 2017) and the growth prospects of global Dextran market for 2018-2023. (rnrmarketresearch.com)
  • Still, no difference has been detected in antithrombotic effectiveness in comparison of intra-arterial and intravenous administration of dextran. (wikipedia.org)
  • Several animal models have been used to study colitis and one such method involves the oral administration of dextran sulfate sodium (DSS) in the drinking water of mice, leading to chronic colitis. (mpbio.com)
  • Another method is the use of cationic polymers such as DEAE-dextran or polyethylenimine (PEI). (wikipedia.org)
  • This transfection technology performs the same tasks as other biochemical procedures utilizing polymers, DEAE-dextran, calcium phosphate, and electroporation. (wikipedia.org)
  • Fructans are linear or branched polymers of mostly ß-fructosyl-fructose linkages. (powershow.com)
  • Dextran is a group of glucose polymers made by certain bacteria. (joycekillian.com)
  • Although they differ dramatically in their degree of transfection efficiency and cytotoxicity, all cationic polymers work in a similar fashion by allowing the formation of nucleic acid-polymer complexes, which adhere to the cell membrane through electrostatic interactions and are taken up by the cell via endocytosis. (thermofisher.com)
  • While cationic polymers can offer increased complex stability, more reproducible results, and higher transfection efficiencies when compared to DEAE‑dextran, their main limitations continue to be cytotoxicity and their limitation to transient transfection studies. (thermofisher.com)
  • Dextran presentation for example EP, USP, and JP Intravenous solutions with dextran function both as volume expanders and means of parenteral nutrition.Such a The hemodilution caused by volume expansion with dextran use and as a volume expander in an example is Sephadex. (joycekillian.com)
  • The hemodilution caused by volume expansion with dextran use and as a volume expander in an example is Sephadex. (joycekillian.com)
  • Dextran 70 The hemodilution caused by volume expansion with dextran an example is Sephadex. (joycekillian.com)
  • Studies were done using commercially available linear dextran and crosslinked polyols such as Sephadex gel, QAE-Sephadex anion-exchange dextran gel, and Amberlite IRA-743, a boron-selective resin which has a functional group of N-methylglucamine. (nii.ac.jp)
  • The stability constant of each complex is similar to that for the Sephadex system : the presence of the fixed cation group in the QAE-Sephadex gel phase did not promote the boron adsorption. (nii.ac.jp)
  • and in certain intravenous fluids to solubilize other factors, such as iron (in a solution known as Iron Dextran). (wikipedia.org)
  • Our results indicate that these new iron formulations have a good stability and availability in vitro and are comparable with the well-known iron dextran complexes. (tghrowbuiild31.tk)
  • The polymer main chain consists of α-1,6 glycosidic linkages between glucose monomers, with branches from α-1,3 linkages. (wikipedia.org)
  • This characteristic branching distinguishes a dextran from a dextrin, which is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages. (wikipedia.org)
  • It is produced from certain bacteria that with α-1,6 glycosidic linkages between glucose molecules and α-1,3 linkages between branches. (drugbank.ca)
  • HTAA-PR is an endo-amylase, catalyzes the release of successive glucose units from non-reducing ends of dextrin and oligosaccharide chains by hydrolyzing both linear and branched glucosidic linkages. (prionsbiotech.com)
  • Other measured bacteria were unaffected by the test substrates except for the Bacteroides-Prevotella group, the growth levels of which were increased on inulin and 6- and 70-kDa dextrans, and the Faecalibacterium prausnitzii group, the growth levels of which were decreased on inulin and 1-kDa dextrans. (asm.org)
  • Dextran was discovered by Louis Pasteur as a microbial product in wine, but mass production was only possible after the development by Allene Jeanes of a process using bacteria. (wikipedia.org)
  • Dextran is now produced from sucrose by certain lactic acid bacteria of the family lactobacillus. (wikipedia.org)
  • Some bacteria coproduce fructans, which can complicate isolation of the dextrans. (wikipedia.org)
  • [ 2 ] Many bacteria, like Leuconostoc , can synthesize dextran from sucrose, and this activity is used commercially to obtain dextran. (drugbank.ca)
  • Recently, we showed that PF4 binds to polyanions on the surface of bacteria, thereby forming multimolecular complexes that are recognized by human anti-PF4/heparin antibodies. (bloodjournal.org)
  • More specifically, we identified the PF4 binding site on gram-negative bacteria as the phosphate groups of lipid A. 7 Based on this observation, we hypothesized that nucleic acids might also form multimolecular complexes with PF4 because they also expose multiple negatively charged phosphate groups. (bloodjournal.org)
  • Microbiome: The complex communities of microorganims (i.e. microbiome)-bacteria, viruses, fungi, protozoa-that reside in and on us determine our health. (purdue.edu)
  • In this family, dextran-40 (MW: 40,000 Da), has been the most popular member for anticoagulation therapy. (wikipedia.org)
  • Bamba S, Andoh A, Ban H, et al: The severity of dextran sodium sulfate-induced colitis can differ between dextran sodium sulfate preparations of the same molecular weight range. (mpbio.com)
  • Experiments in mice showed that the severity of a dextran sodium sulfate model of colitis was much reduced when the animals were pretreated with DNA from Helicobacter pylori . (medpagetoday.com)
  • IMMS was also able to identify a product within a mixture of maltooligosaccharides treated with the potential anti-tuberculosis drug target Mycobacterium tuberculosis GlgB branching enzyme. (jic.ac.uk)
  • Aldolase C (Aldoc, also known as "zebrin II"), a brain type isozyme of a glycolysis enzyme, is expressed heterogeneously in subpopulations of cerebellar Purkinje cells (PCs) that are arranged longitudinally in a complex striped pattern in the cerebellar cortex, a pattern which is closely related to the topography of input and output axonal projections. (jove.com)
  • Moreover, heparin-induced anti-human-PF4/heparin antibodies cross-reacted with human PF4/nucleic acid and PF4/aptamer complexes, as shown by an enzyme immunoassay and a functional platelet activation assay. (bloodjournal.org)
  • Secondly, there is activation of the enzyme alliancepartners (ACAT), which atrificial free cholesterol to complex ester of cholesterol, which is a form of accumulation of cholesterol in the cell. (russianpatents.com)
  • Fusion events between OPRTase and ODCase, which have led to the formation of the bifunctional enzyme UMPS, have occurred distinctly in different branches of the tree of life. (wikipedia.org)
  • However, when enzyme concentrations are higher, these complex kinetics do not manifest. (wikipedia.org)
  • Dendrimer-like star-branched block copolymers with controlled segment sequence and their star-like dendrigraft derivatives were synthesised through anionic polymerisation and coupling reactions. (publish.csiro.au)
  • Recently, UA scientists began to work on the synthesis of branched copolymers Dextran-Poly-N-isopropyl acrylamide and the possibility to create nanocomposites into these matrices for antitumor therapy. (enterprise-europe.co.uk)
  • It is hypothesised that dextrans may form water-soluble complexes with LAs that remain at the site of injection longer than the unbound drug, dextran also alters the pH of the injected LA solution, and this alkalinisation may contribute to the prolongation of action8. (ispub.com)
  • The mechanism of action is unclear, but it is hypothesised that dextrans may form water-soluble complexes with LAs that remain at the site of injection longer than the unbound drug, due to an increase in viscosity with reduced diffusion of the complex7. (ispub.com)
  • 7. The process as claimed in claim 1, wherein the statin and the at least one further component and/or the at least one water-soluble ionic polymeric component are present in the coating as a complex or mixed salt with low solubility in water. (patentgenius.com)
  • Branched, high molecular weight PEI (˜25 kDa) is an effective polymeric carrier. (patentsencyclopedia.com)
  • Improved zinc ferrite oxidative dehydrogenation catalyst can be prepared by co-precipitating the catalysts from a solution of zinc and iron ions in the presence of a high molecular weight polyhydric material such as dextran in a 2 to 4 normal alkali metal hydroxide solution. (google.es)
  • These findings indicate that dextrans induce a selective effect on the gut flora, short-chain fatty acids, and gas production depending on their length. (asm.org)
  • Solutions of fluorescently-labelled dextran can be perfused through engineered vessels to analyze vascular permeability Dextran is used to make microcarriers for industrial cell culture Orally-administered dextran sodium sulphate is used to induce colitis in animal models of inflammatory bowel disease. (wikipedia.org)
  • PF4/aptamer complexes can induce an immune response resembling heparin-induced thrombocytopenia. (bloodjournal.org)
  • Prolongation Of Action Of Lignocaine By Addition Of Dextran 40 In Brachial Plexus Block. (ispub.com)
  • The present study is designed to asses the prolongation of action of lignocaine by addition of dextran 40 in brachial plexus block. (ispub.com)
  • In our study we used dextran 40 with lignocaine to assess the efficacy, safety and duration of brachial plexus block. (ispub.com)
  • After entering the GI tract wall, sympathetic axons branched extensively to form complex terminal arrays within the myenteric ganglia and adjacent tertiary plexus. (purdue.edu)
  • Sympathetic arbors also formed long rectilinear multiply branched arrays of neurites within the circular muscle and its associated secondary plexus. (purdue.edu)
  • Quantitative three-dimensional imaging studies revealed that a plexus of branched interconnected vessels developed in small intestinal villi during the period of postnatal development that coincides with assembly of a complex society of indigenous gut microorganisms (microbiota). (pnas.org)
  • Sprouting occurs toward the periphery in the primary plexus (P1 and P5, arrows) and subsequently into deeper layers (P8, arrows), where again branching and fusion leads to plexus formation. (nih.gov)
  • It is important to understand that starch is actually a complex sugar. (prionsbiotech.com)
  • Each starch molecule is long chain of up to a thousand glucose molecules bonded either in a straight line or branching like the leafless arm of tree. (prionsbiotech.com)
  • Close to 70% of dextran-40 is excreted in urine within the first 24 hours after intravenous infusion, while the remaining 30% are retained for several more days. (wikipedia.org)
  • Intraoperative use of dextran is associated with into clinical practice in 1947 as a colloid plasma volume expander.1 Since then, it has been noted to have multiple Dextran has traditionally been used in infusion fluid and volume expander products. (joycekillian.com)
  • Dextran is a complicating contaminant in the refining of sugar because it elevates the viscosity of sucrose solutions and fouls plumbing. (wikipedia.org)
  • CONCLUSIONS: Biological samples of complex isobaric oligosaccharides can be analysed using IMMS in the negative mode providing facile analyses and high sensitivity without the need for either derivatisation or chromatographic separation. (jic.ac.uk)
  • To study and analyze the global Dextran consumption (value & volume) by key regions/countries, product type and application, history data from 2013 to 2017, and forecast to 2023. (rnrmarketresearch.com)
  • Focuses on the key global Dextran manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years. (rnrmarketresearch.com)
  • To analyze the Dextran with respect to individual growth trends, future prospects, and their contribution to the total market. (rnrmarketresearch.com)
  • DELTAH values were comparable to those for the complex formation ob borate with monosaccharides and the borate concentration dependence of boron adsorption is a characteristic property of the crosslinked dextran. (nii.ac.jp)
  • Precursor cells of the distal nephron in the interconnection zone exhibit a characteristic morphology consisting of ill-defined epithelial junctional complexes but without expression of mesenchymal markers such as vimentin and Snai2. (asnjournals.org)
  • These data indicate that the formation of anti-PF4/heparin antibodies in postoperative patients may be augmented by PF4/nucleic acid complexes. (bloodjournal.org)
  • Transfection with PEI-nucleic acid complexes is significantly more efficient than observed with DEAE-dextran, however PEI demonstrates a dose-dependent cytotoxicity. (patentsencyclopedia.com)
  • Nucleic acid-cationic polymer complexes are formed via electrostatic interactions between the polymer and phosphate backbone of the nucleic acid. (thermofisher.com)
  • Add the nucleic acid-cationic polymer complexes to the cells. (thermofisher.com)
  • Nucleic acid-cationic polymer complexes are taken up by the cell via endocytosis and are released into the cytoplasm. (thermofisher.com)
  • Intravenous solutions with dextran function both as volume expanders and means of parenteral nutrition. (wikipedia.org)
  • Strucural Formula:, Dextrans are glucopolysaccharides used as volume expanders. (joycekillian.com)
  • Dextrans are used therapeutically as plasma volume expanders and anticoagulants. (joycekillian.com)
  • Source: Diseases Database Dextran 60 (70) has a half-life of Volume Expanders. (joycekillian.com)
  • The worldwide market for Dextran is expected to grow at a CAGR of roughly 4.2% over the next five years, will reach 220 million US$ in 2023, from 170 million US$ in 2017, according to a new GIR (Global Info Research) study. (rnrmarketresearch.com)
  • Over the next five years, LPI(LP Information) projects that Dextran will register a 4.2% CAGR in terms of revenue, reach US$ 220 million by 2023, from US$ 170 million in 2017. (rnrmarketresearch.com)
  • The invention relates to ligands, which are bicyclopentadiene acids, and their complexes and conjugates for use as contrast agents in magnetic resonance imaging (MRI). (russianpatents.com)
  • One step synthesis enzymology receptors is a major manufacture process of dextran. (rnrmarketresearch.com)
  • The University has patented a method for the synthesis of resistant nanosystems in branched polymer matrices. (enterprise-europe.co.uk)
  • Dextran chains are of varying lengths (from 3 to 2000 kilodaltons). (wikipedia.org)
  • Importantly, we found that when the anti-dextran V H CDR2 replaced CDR2 of an anti-dansyl V H , the glycosylation site was used, but H chains were withheld in the endoplasmic reticulum and did not traffic to the Golgi apparatus. (jimmunol.org)
  • Here, we summarize current knowledge of the cellular composition of the brain barriers with a specific focus on describing the molecular constituents of their junctional complexes. (nih.gov)
  • We close by providing a brief overview on experimental tools allowing for reliable in vivo visualization of the brain barriers and their junctional complexes and thus the respective CNS compartments. (nih.gov)
  • Schematic representation of the junctional complexes of the BBB. (nih.gov)
  • Type A chitinases are acidic, display partial latency, show an unusual affinity to dextran gel and act weakly on colloidal chitin. (microbiologyresearch.org)
  • The antithrombotic effect of dextran is mediated through its binding of erythrocytes, platelets, and vascular endothelium, increasing their electronegativity and thus reducing erythrocyte aggregation and platelet adhesiveness. (wikipedia.org)
  • Dextrans also reduce factor VIII-Ag Von Willebrand factor, thereby decreasing platelet function. (wikipedia.org)
  • The tight electrostatic binding of the chemokine platelet factor 4 (PF4) to polyanions induces heparin-induced thrombocytopenia, a prothrombotic adverse drug reaction caused by immunoglobulin G directed against PF4/polyanion complexes. (bloodjournal.org)
  • 4 In HIT, multimolecular complexes composed of PF4, heparin, and anti-PF4/heparin IgG cross-link platelet FcγIIa receptors, 5 triggering platelet activation, microparticle formation, and thrombin generation, with ∼50% of affected patients developing thrombosis. (bloodjournal.org)
  • Medicinally, Dextran is used as an antithrombotic (anti-platelet) in order to reduce blood viscosity and also as a volume expander for those with anemia. (blogspot.com)
  • Finally, administration of PF4/44mer-DNA protein C aptamer complexes in mice induced anti-PF4/aptamer antibodies, which cross-reacted with murine PF4/heparin complexes. (bloodjournal.org)
  • We have studied a murine anti-α(1→6) dextran V H that contains a carbohydrate in complementarity-determining region 2 (CDR2). (jimmunol.org)
  • The murine anti-α(1→6) dextran V H gene 14.6b.1, used in previous investigations of V region glycosylation, was found to contain a complex N -linked carbohydrate at Asn 58 in CDR2 ( 9 ). (jimmunol.org)
  • It has been studied dextran-polyacrylamide matrices as nanocarrier for biomedical applications. (enterprise-europe.co.uk)
  • Formation of a functional renal network requires the interconnection of two epithelial tubes: the nephron, which arises from kidney mesenchyme, and the collecting system, which originates from the branching ureteric epithelium. (asnjournals.org)
  • 2 - 5 In the formation of the primary mouth in Xenopus laevis and the foregut of C. elegans, apoptosis 6 , 7 and reorientation of epithelial junction complexes, 8 respectively, are critical cellular strategies. (asnjournals.org)
  • The negatively charged DNA binds to the polycation and the complex is taken up by the cell via endocytosis. (wikipedia.org)
  • Fischer 344 rats ( N = 50) received injections of dextran biotin into the left celiac and superior mesenteric ganglia. (purdue.edu)
  • Mice were anesthetized and unilateral injections of dextran-amine made into lumbosacral DRGs (L5-S2). (edu.au)
  • Dextran has also been used in bead form to aid in bioreactor applications. (wikipedia.org)
  • This carbohydrate remains high mannose rather than being processed to a complex form, as would be expected for glycans on exposed protein loops. (jimmunol.org)
  • the most highly conserved regions of the endotracheal tube is inflated around the bud failing to form a complex chronic condition. (junoon.com)
  • Olfactory and visual projection neurons form distinct synaptic complexes (microglomeruli, MG) with KC dendrites in the olfactory lip or visual collar of the MB calyx, respectively [ 18 , 22 , 28 - 30 ]. (royalsocietypublishing.org)
  • Dextran 40, Powder, USP is used as an antithrombotic in order to reduce blood viscosity. (spectrumchemical.com)
  • Medicinally, dextran is used as an antithrombotic (antiplatelet), to reduce blood viscosity, and as a volume expander in hypovolaemia. (joycekillian.com)
  • Linear and branched 1-kDa dextrans produced significant increases in Bifidobacterium populations. (asm.org)
  • Dextran also increases blood sugar levels. (wikipedia.org)
  • In Plasmodium falciparum, the OPRTase-OMPDCase complex increases the kinetic and thermal stability when compared to monofunctional enzymes. (wikipedia.org)
  • Dextran as well presents ophthalmic applications as solutions or ointments for the temporary relief of xerophthalmia or minor ocular irritations. (drugbank.ca)
  • Angiogenesis is a complex, multistep process in which ECs of preexisting blood vessels, challenged by appropriate biochemical and physical cues, dynamically remodel their cell-to-cell and cell-to-matrix adhesions and reorganize themselves into a mature, hierarchically organized system of hollow endothelial tubes that is eventually stabilized by interaction with pericytes. (rupress.org)
  • It controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately regulated to result in more complex morphogenetic events, such as tubular sprouting, fusion, and network formation. (nih.gov)
  • h) Dextran perfusion (false colored in red) revealing endothelial lumina. (nih.gov)
  • Outside of these features, larger dextrans, which do not pass out of the vessels, are potent osmotic agents, thus have been used urgently to treat hypovolemia. (wikipedia.org)
  • The primary afferents of the pathway reside in the trigeminal ganglion, and their axons split into a peripheral branch innervating blood vessels in the cerebral dura and pia maters and a central branch projecting to the spinal trigeminal nucleus (SpV). (jneurosci.org)
  • 4 Connexin40-null mice develop AV nodal conduction delays 5,6 and impaired conduction in the bundle branches. (ahajournals.org)
  • Dextran is also used for the prevention of profound postoperative venous thrombosis. (drugbank.ca)
  • Alternatively, the addition of dextran alters the pH of the injected LA solution, and this alkalinisation may contribute to the prolongation of action8. (ispub.com)
  • citation needed] Dextran can be used in an ATPS for PEGylation Dextran is used in the osmotic stress technique for applying osmotic pressure to biological molecules. (wikipedia.org)
  • When labelled with technetium Tc99m, dextran 75 is intravenously administered as an imaging agent to detect and diagnose conditions in the vascular compartment such as pericardial effusion or ventricular aneurysm. (drugbank.ca)
  • Dextrans are available in multiple molecular weights ranging from 3,000 Da to 2,000,000 Da. (wikipedia.org)
  • Systematic assessment of RNA and DNA constructs, as well as 4 aptamers of different lengths and secondary structures, revealed that increasing length and double-stranded segments of nucleic acids augment complex formation with PF4, while single nucleotides or single-stranded polyA or polyC constructs do not. (bloodjournal.org)
  • B NMR spectroscopy was employed to elucidate the nature of the complex formation of borate with the polyols. (nii.ac.jp)
  • Some of the ligands and complexes are also useful as a means of caring for the oral cavity and as agents for the inhibition of scale formation in water systems processing. (russianpatents.com)
  • The role of structure and molecular weight in fermentation selectivity in linear α-1,6 dextrans and dextrans with α-1,2 branching was investigated. (asm.org)
  • The linear 1-kDa dextran produced lower total gas and shorter time to attain maximal gas production compared to those of the 70-kDa dextran (branched) and inulin. (asm.org)
  • Dextran can be used as a stabilizing coating to protect metal nanoparticles from oxidation and improve biocompatibility. (wikipedia.org)
  • Red emitting europium (III) complexes Eu(TFAAN) 3 (P(Oct) 3 ) 3 (TFAAN = 2-(4,4,4-Trifluoroacetoacetyl)naphthalene, P(Oct) 3 = trioctylphosphine) chelated on carboxymethyl dextran coated superparamagnetic iron oxide nanoparticles (CMD-SPIONs) was synthesized and the step wise synthetic process was reported. (mdpi.com)
  • When harvesting sugar cane is damaged climatically or mechanically and such microorganisms will attach the damaged portion, the microorganisms will assimilate the cane sugar and produce viscous dextran. (prionsbiotech.com)
  • Most nerve endings were located in detrusor muscle where the three types could be identified as having: 'branching', 'simple', or 'complex' morphology. (edu.au)
  • 1. An antigenic product, comprising a dendritic polymer, built on a core molecule which is at least difunctional so as to provide branching and containing up to 16 terminal functional groups to which an antigenic peptide, that comprises an epitope of a deposit-forming polypeptide involved in plaque-forming disease or disorder, is joined by covalent bonds. (freepatentsonline.com)
  • They often contain terminal fucose and/or sialic acid molecules and may take one of several different structural forms: biantennary, branched, or bisected. (jimmunol.org)
  • Cm above its base and has offices in west virginia, the midfield terminal complex at the heart and mind as they move and interact with one push of a growing, progressive mile class. (sewanee.edu)
  • This report focuses on the Dextran in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. (rnrmarketresearch.com)
  • Dextran coupled with a fluorescent molecule such as fluorescein isothiocyanate can be used to create concentration gradients of diffusible molecules for imaging and allow subsequent characterization of gradient slope. (wikipedia.org)
  • 1 Chemical, physical and biochemical stimuli have been employed to control the material function in an often programmable and complex manner. (rsc.org)