Compassionate Use Trials

Treatment Outcome

Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America<...

Compassionate use policy for orphan drugs - Beyond Achondroplasia

Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome - Full...

AB Science announces that FDA approves first compassionate use of masitinib in amyotrophic lateral sclerosis

This Record Contains Information About the Mepolizumab Compassionate Use Product Activities: 104317: An Open-Label...

Compassionate Use for Public Health | Annals of Internal Medicine | American College of Physicians

Treatment patterns and clinical outcomes with pazopanib in patients with advanced soft tissue sarcomas in a compassionate use...

Compassionate use for upcoming Dr. Wise Young trial

Regenerative Medicine | EMBO Molecular Medicine

Expanded Access, Compassionate Use & Right to Try in Medicine: Amyloidosis Research Consortium Patient Webinar | Bioethics...

FDA approves humanitarian device exemption for instrument set to treat rare disorder affecting fetal twins | KARL STORZ...

Aethlon Medical Announces Initiation of Compassionate-Use Program to Treat Hepatitis C Virus (HCV)

Amprenavir expanded access program announced today

uso compassivo de medicamento orfão Archives - Beyond Achondroplasia

FDA Grants Compassionate Use Access to Drug for ALS Patient: An Overview of the Issues Surrounding Expanded Access to...

VIVUS: Pulmonary Arterial Hypertension (PAH)

Rock to the left, hard place to the right: One dilemma of compassionate use

Help Us Make FDA Live Up to Its Compassionate Use Rule! | The Alliance for Natural Health

Compassionate Use and the Animal Rule

Compassionate Use of Omegaven® in the Treatment of Parenteral Nutrition Induced Hepatic Injury

NM Compassionate Use Medical Marijuana Act

DI-fusion Compassionate use of a 5-HT3-receptor antagonist,...

Silagra wirkt nicht clofazimine compassionate use paxil neurological side effects buy cheap xanax from india

Expanded Access: Analysis of the Latest Developments - Webinar Recording/Transcript | CenterWatch

Expanded Access Program | Novelion

Humanitarian Device Exemption (HDE)

Can-Fite Gears Up to Initiate Pivotal Phase III Liver Cancer Study | The Pharmaceutical Marketing Group

Berlin heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children<...

Amifampridine - Wikipedia

REVISED: NEW EXPANDED ACCESS PROGRAM ANNOUNCED FOR IDIOPATHIC PULMONARY FIBROSIS PATIENTS

Dr. Gerald Pierone - Facial Rejuvenation FL

Arthritis in Dogs | Stem Cell Canine | Hip Elbow Dysplasia | Cat | Fat Adipose Vet Stem Veterinarian Horse Pain Tendon Ligament...

Most recent papers in the shared collection Ebola | Read by QxMD

Beyond Pesticides Daily News Blog » Blog Archive California Releases New Guidelines for Pesticide Use on Marijuana - Beyond...

Audio: Right-to-Try experimental drug bill again appears headed to Gov. Brown | 89.3 KPCC

Cannabisöl legal in new jersey

Post-Approval Studies (PAS)

SynCardia Sets New Records for Total Artificial Heart Implants, Revenue and Profit in 2012

ViiV Announces Expanded Access to Once-a-Day Integrase Inhibitor ... But Activists Are Concerned About Its Potential Misuse -...

Expanded Access to Investigational Drugs: What Physicians and the Public Need to Know about FDA and Corporate Processes, Dec 15...

Body Size | REACH

MRCT Center Bioethics Collaborative published framework and toolkit on Expanded Access - The Multi-Regional Clinical Trials...

State Right-to-Try Laws Begin to Spread, But Are They Only a Placebo? - The Forrestal Law Office Co., L.P.A.

Guidelines for Treatment With Regorafenib in Patients With Gastrointestinal Stromal Tumors (GIST) After Disease Progression on...

ORBi: Browsing ORBi

GEs Molecular Imaging Agent Gains FDA Priority Review | Imaging Technology News

JCI - In press preview

Sofosbuvir-based therapy effective for hepatitis C patients with decompensated cirrhosis | aidsmap

Xpovio Open to Advanced Myeloma Patients Outside US via Access Program - MYELOMA360

Access Program | Access Cambodia

Berlin Heart is an Effective Alternative for Children Waiting for Heart Transplant

Enterra Therapy - G-PACT

Multicenter Expanded Access Protocol of Allogeneic Epstein-Barr Virus Cytotoxic T Lymphocytes (EBV-CTLs) for Patients With EBV...

Page 10 | EIFL

CIW national report calls for upstream health promotion and expanded access to CHCs - Stonegate Community Health Centre

Ring vaccination with rVSV-ZEBOV under expanded access in response to an outbreak of Ebola virus disease in Guinea, 2016: an...

Louis B. Seltzer

Responses to the COVID-19 pandemic in June 2020

Compassionate release

Clinical trial

Anthony Casso

Catherine Nevin

Dan and Frank Carney

Epitopoietic Research Corporation

Will Matthews (rugby league)

Palliative care

Hydroxychloroquine

Chloroquine

Association of American Physicians and Surgeons

Chloroquine and hydroxychloroquine during the COVID-19 pandemic

Allan-Herndon-Dudley syndrome

Marilla Ricker

2015 Oklahoma State University homecoming parade attack

Leronlimab

Avita Medical

CCR5 receptor antagonist

Glossary of clinical research

MIS416

2009 in England

Steve Kubby

Release of Abdelbaset al-Megrahi

Lynne Stewart

2018 Équateur province Ebola outbreak

Innate Immunotherapeutics

Georg-Hans Reinhardt

Remdesivir

Universal basic income around the world

Timeline of the COVID-19 pandemic in the Philippines (2021)

Kiran Mazumdar-Shaw

Grace Hutchins

Oaxaca en la historia y en el mito

Social service agent

Stephen Ireland

Daniel Vidot

Premiership of John Major

Kraków-Płaszów concentration camp

Di-deuterated linoleic acid ethyl ester

List of Danny Phantom characters

Joe Hockey

Philip Nitschke

William K. Oh

List of The Archers characters

Attachment parenting

Autism Speaks

Matthew Shepard

The Brothers Karamazov

Left Book Club

High Sparrow

Pulitzer Prize for Editorial Writing

Ilka Gedő

Imprisonment

Saul Deeney

Doctor Who

Joe Manchin

Freedom Writers Foundation

20172

• Natasha Darcy is on trial for allegedly killing her boyfriend, Matthew Dunbar, who died on August 2, 2017. (blogspot.com)
• According to the trial reports Matthew Dunbar died on August 2, 2017 at around 2 am with an exit bag and helium, one of the suicide methods promoted by Philip Nitschke and Exit. (blogspot.com)

Exemptions1

• Since many physicians are currently using treatments that rely on compassionate-use exemptions or off-label indications to treat patients with COVID-19, it is crucial that they have access to the most up-to-date research evidence to inform their treatment decisions. (bvsalud.org)

20204

• To facilitate the implementation of the AVAREF Guidelines for Clinical Trials, a one-page document explaining the AVAREF Guideline consultation and subsequent approval process was circulated to Member States in May 2020. (who.int)
• DALLAS - Oct. 13, 2020 - The COVID-19 pandemic has led to new rules and expectations for cancer clinical trials. (newswise.com)
• In March 2020, the Food and Drug Administration issued guidance on the conduct of clinical trials during the COVID-19 pandemic. (newswise.com)
• Due to the COVID-19 pandemic, the FDA designated remdesivir for 'compassionate use' in March 2020, allowing patients with serious or life-threatening cases of the virus to have access to the drug. (pharmacytimes.com)

Merciful1

• In the name of God, the Compassionate the Merciful. (juancole.com)

Multicenter4

• This will likely change over time - the World Health Organization (WHO) is working on a randomized, multicenter adaptive trial that will cover "multiple sites," so far unspecified. (medscape.com)
• This Phase II, multicenter, randomized, double-blind, placebo-controlled trial was designed to estimate the efficacy and characterize the safety of bevacizumab when combined with carboplatin + paclitaxel chemotherapy compared with carboplatin + paclitaxel chemotherapy alone in patients with previously untreated metastatic melanoma. (stanford.edu)
• These opportunities will range from homegrown studies to multicenter trials HFH is involved in. (henryford.com)
• Survival, safety, and prognostic factors for outcome with Regorafenib in patients with metastatic colorectal cancer refractory to standard therapies: results from a multicenter study (REBECCA) nested within a compassionate use program. (cdc.gov)

Investigational8

• Four COVID-19 multinational adaptive trials are already underway, one starting with the investigational agent remdesivir, and two with the HIV drug combination of lopinavir-ritonavir. (medscape.com)
• While we do not currently offer investigational therapies outside of our clinical trials, you and your physician may determine that enrolling in a trial may be an option for you. (concertpharma.com)
• If a patient is unable to gain access to an unapproved or investigational medicine through a clinical trial , they may be able to gain access to this medicine via an early access program, if this is available. (gene.com)
• Granting access to an investigational medicine must not interfere with the completion of important clinical trials that could support the FDA approval of the medicine or otherwise compromise the potential development of the investigational medicine. (gene.com)
• Patients seeking to join an EAP must not qualify for any ongoing or upcoming clinical trials of the investigational medicine. (gene.com)
• Whenever possible, patients will be referred to ongoing clinical trials as the primary way to access investigational medicines. (gene.com)
• Providing an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. (bvsalud.org)
• Treatment of monkeypox with tecovirimat as a first-line agent is available through CDC for compassionate use through an investigational drug protocol. (cdc.gov)

Expanded Access4

• Known as compassionate use, or expanded access, the protocol was formalized in the 1980s as a response to AIDS activists who were frustrated with the pace of approval for antiretrovirals. (harpers.org)
• Early access programs can include expanded access programs (EAP) or a compassionate use (CU) program. (gene.com)
• Once the FDA approves a medicine, neither existing expanded access programs nor compassionate use are available. (gene.com)
• Also called expanded access trial. (bvsalud.org)

Programmes2

• What consequences does this refusal have for patients in clinical trials or compassionate use programmes? (europa.eu)
• The company informed the CHMP that there are no consequences for patients currently included in clinical trials or compassionate use programmes with Istodax. (europa.eu)

Efficacy6

• Walang garantiya ang FDA do'n sa quality at saka efficacy ng gamot lalo na kung clinical trial drug pa," Domingo said. (gmanetwork.com)
• The FDA does not guarantee its quality and efficacy, especially if it's a clinical trial drug. (gmanetwork.com)
• The first SIMPLE trial is evaluating the safety and efficacy of 5-day and 10-day dosing regimens of remdesivir in hospitalized patients with severe manifestations of COVID-19. (pharmacytimes.com)
• A second SIMPLE trial is evaluating the safety and efficacy of 5-day and 10-day dosing durations of remdesivir administered intravenously in patients with moderate manifestations of COVID-19, compared with standard of care. (pharmacytimes.com)
• Future efficacy trials are warranted. (jrheum.org)
• 37. Palmeira L, Pinto-Gouveia J, Cunha M. Exploring the efficacy of an acceptance, mindfulness & compassionate-based group intervention for women struggling with their weight (Kg-Free): A randomized controlled trial. (bvsalud.org)

Treatments5

• Clinical trials are the main way that doctors find better treatments. (cancer.net)
• In the United States, the Food and Drug Administration (FDA) says new drugs and other treatments must be tested in clinical trials. (cancer.net)
• The existing drug development system "has failed miserably" for people with glioblastoma brain tumors, according to Al Musella, DPM, President of the Musella Foundation for Brain Tumor Research & Information, Inc. In partnership with Cancer Commons, his organization's Brain Tumor Virtual Trial aims to speed discovery of promising new glioblastoma treatments. (cancercommons.org)
• As patients are treated, we learn how to use the treatments better, but the rigid structure of a phase 3 trial doesn't allow for modifications midstream. (cancercommons.org)
• Now that the "deconditioning" theory championed in the PACE trial has essentially been discarded, members of the CBT/GET ideological brigades have adopted other justifications for continued adherence to their favored treatments. (elsewhere.org)

Prosecutors1

• In both trials, prosecutors used most or all of their strikes to remove black jurors. (cdpl.org)

20192

• Announced today by Gilead Sciences, these topline results were culled from an open-label phase 3 SIMPLE trial evaluating 5-day and 10-day dosing durations of the antiviral in hospitalized patients with severe manifestations of the coronavirus disease 2019 (COVID-19). (pharmacytimes.com)
• She also shared her view the financier, found hanged in his cell in New York in 2019 aged 66 while he was awaiting trial for sex trafficking, was murdered behind bars. (yahoo.com)

Patients25

• Kalil emphasized there is no way to know whether patients actually benefit from a drug or are harmed by it without a randomized clinical trial - a well-established principle of evidence-based medicine that can be forgotten during a crisis. (medscape.com)
• Evaluating long-term safety of CTP-543 and to assessing long-term effects of CTP-543 in adult patients with chronic, moderate-to-severe alopecia areata who completed 24 weeks of treatment in a previous qualifying CTP-543 clinical trial. (concertpharma.com)
• These summaries (also called layperson summaries, plain language summaries, lay language summaries, simple summaries, and trial results summaries) are intended to make the clinical results of these studies understandable and accessible to patients, healthcare providers, caregivers, researchers, and a general audience. (pfizer.com)
• To protect patient safety, changes such as utilizing remote consents, conducting telehealth study visits, and shipping oral study treatment to patients' homes have streamlined the cancer clinical trial participation process. (newswise.com)
• As a result of these measures, patients no longer had to visit in person to consent to participate in a trial - a lengthy process that involves learning about the risks and benefits of participation. (newswise.com)
• For years, there have been calls to simplify trial protocols and procedures, which have become highly complex and burdensome on patients and their families. (newswise.com)
• Without such reform, trials will be accessible and relevant to a shrinking minority of patients. (newswise.com)
• So far, there are only results on 275 trial patients. (lifenews.com)
• Through the Stanford University Head and Neck Tumor Board, clinical trials are conducted which involve all aspects of care for patients with head and neck cancer. (stanford.edu)
• Stanford is currently not accepting patients for this trial. (stanford.edu)
• This was a Phase 2a trial to investigate the safety and biological activity of the RIX-2 Regimen in patients with untreated, resectable squamous cell cancer of the head and neck (HNSCC). (stanford.edu)
• Cardiology Today PRECISE is The Randomized Clinical Trial of Adipose-Derived Stem Cells in Treatment of Non Revascularizable Ischemic Myocardium, a double blind, placebo-controlled trial involving 27 patients with chronic ischemic heart disease with HF, angina or both, who were not eligible for percutaneous or surgical revascularization. (cellmedicine.com)
• As described by the FDA, EAPs and CU are only available for specific patients with no other available treatment options, including clinical trials, and are not without risks. (gene.com)
• 1 Over the last 6 years, 47 patients with SCD have been treated with LV gene therapy in two related clinical trials (ClinicalTrials.gov: NCT02140554 and NCT04293185 ) that have evolved from the use of steady-state bone marrow (BM) for collection of hematopoietic stem cells (HSCs) along with standard manufacturing techniques and supportive care to now plerixafor mobilization with refined manufacturing techniques and obligatory transfusion supportive care. (cell.com)
• Compassionate use trials allow patients to receive promising but not yet fully studied or approved therapies when no other treatment option exists. (bvsalud.org)
• This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. (clinicaltrialsgps.com)
• For arm 2 only: Male patients (regardless of age) previously treated with concizumab via compassionate use. (who.int)
• There are not enough patients for the number of trials needed. (cancercommons.org)
• About 10% of adult glioblastoma patients-about 2,000 per year-enter clinical trials. (cancercommons.org)
• There are currently 318 glioblastoma trials open for enrollment, which means only six patients are available per trial per year. (cancercommons.org)
• it takes years to accrue enough patients, and many trials never do. (cancercommons.org)
• For now, AmpliPhi is able to recruit patients under the FDA's "compassionate use" pathway, making it mostly a case-by-case situation for now when other antibiotics have failed. (vpsfoundation.org)
• Everyone who works at NIH on these trials has an ability to combine devotion to their work and passion and care of individual patients that borders on the profound. (medlineplus.gov)
• A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196. (cdc.gov)
• From clinical trials to clinical practice: predictors of response to erlotinib in advanced non-small cell lung cancer patients pretreated with chemotherapy. (cdc.gov)

Care11

• The doctor and other health care staff check your health regularly during the clinical trial. (cancer.net)
• Under the Affordable Care Act, insurers are now prohibited from dropping or limiting coverage for participants who choose to enroll in a clinical trial to treat cancer or other life-threatening disease, which could increase access to and participation in this kind of research. (prevention.com)
• However, the drug company has refused to release the drug for compassionate care because they are trying to take it to market. (harpers.org)
• In fact, he and his team are leading a clinical trial with the hope of solidifying a new standard of care. (bestcare.org)
• If you want to understand why some of us care so much about compassionate conservatism, it's that we are moved by the people. (heritage.org)
• We place particular emphasis on the compassionate delivery of care and news. (henryford.com)
• SCI offers leading edge research and compassionate care with over 250 actively recruiting clinical trials, investigating a broad spectrum of cancer conditions. (stanford.edu)
• For the first time, an unlicensed Ebola vaccine tested in clinical trials during the West African outbreak is being offered under "compassionate use" to health care workers (HCWs) and front line workers (FLWs) at health facilities and border crossings in countries bordering Ebola hotspots in the Democratic Republic of Congo (DRC). (cdc.gov)
• Support for those who wish to receive end of life care in the comfort of their own home, from a trained and compassionate carer. (berkeleyhomehealth.com)
• The NIH Accelerating Covid-19 Therapeutics Interventions and Vaccines (ACTIV) trials public-private partnership to develop a coordinated research strategy has several ongoing protocols that are adaptive to the progression of standard care. (medscape.com)
• The firm takes pride in its commitment to providing personalized attention and representation for each case, ensuring that all clients receive compassionate care, support, and guidance as well as comprehensive legal services. (lasvegasinquirer.com)

Collaborative3

• Many of the larger studies are collaborative, multinational trials linking study initiators in the United States, Canada, China, and France with clinical researchers in Southeast Asia, Australasia, and a dozen European countries. (medscape.com)
• It seems that yoga is the magic pill that might finally drive out county towards a compassionate healthy and collaborative future. (teenyoga.com)
• The mission of this program is to provide safe, compassionate, collaborative, evidence-based and cost-effective treatment to the whole patient. (asam.org)

Litigation2

• We were able to settle a highly contentious case after years of litigation just a few weeks before trial. (mccammongroup.com)
• Our lawyers have a strong reputation for effective and compassionate deportation defense litigation. (yellowbot.com)

Participation3

• Participation in our clinical trials plays a vital role in helping develop new medicines. (concertpharma.com)
• Geographic limitations to participation in a clinical trial would generally not meet this criterion. (gene.com)
• That being said, I talked to one patient who described to me how her personal doctor had actively discouraged her participation in the trials the NIH offered. (medlineplus.gov)

Guidance2

• This document provides guidance to NRAs, ECs, trial sponsors and their investigators on a joint review model for submission and review of CTAs in Africa. (who.int)
• Following guidance from federal agencies, institutions such as UT Southwestern's Harold C. Simmons Comprehensive Cancer Center led efforts to adapt clinical trial operations. (newswise.com)

Intervention2

• To conduct a proof-of-concept randomized trial of an Internal Family Systems (IFS) psychotherapeutic intervention on rheumatoid arthritis (RA) disease activity and psychological status. (jrheum.org)
• Moreover, obtaining a quick answer to the question of whether or not a particular intervention is effective can help investigators involved in the many ongoing clinical trials to change focus and pivot to more promising alternatives. (bvsalud.org)

Clinical trials work2

• How do clinical trials work? (cancer.net)
• Our goal was to get everything reactivated as quickly as possible, but we needed time to figure out how to make clinical trials work in the wake of COVID-19," says Erin Williams, MBA, administrative director of Clinical Research Operations at the Simmons Cancer Center. (newswise.com)

Experimental4

• Kalil is leading the first clinical trial in the United States of an experimental treatment for COVID-19, the National Institutes of Health (NIH)-sponsored Adaptive COVID-19 Treatment Trial (ACTT). (medscape.com)
• Because brincidofovir was still undergoing clinical trials - contrary to Aimee's post, the drug had not yet been proved safe or effective - it could be procured only through a special FDA protocol that allows doctors to prescribe experimental drugs. (harpers.org)
• The patient was approved for this experimental surgery as a one-time compassionate case. (foxla.com)
• During the NIOSH evaluation, experimental work was in the clinical trial stage, and the doses and administration method were agreed upon by the Food and Drug Administration (FDA) as part of their approval process. (cdc.gov)

Treatment12

• They also need to make sure the clinical trial treatment is right for you. (cancer.net)
• As shown in the Table (see below) of all COVID-19 randomized controlled treatment trials, almost 60 of such trials are planned, recruiting, or underway. (medscape.com)
• China is currently running more randomized treatment trials than any other country, closely followed by the United States. (medscape.com)
• The American Bar Association's Tort Trial and Insurance Practice Section's Animal Law Committee's annual Excellence in the Advancement of Animal Law Award recognizes exceptional work by an Animal Law Committee member who, through commitment and leadership, has advanced the humane treatment of animals through the law. (avvo.com)
• Mr. Trump received that antibody treatment under a compassionate use agreement with the company. (lifenews.com)
• Pimasertib, an oral chemotherapy drug, was being called 'up and coming' for ovarian cancer treatment by doctors at big-name hospitals, and had been found to be effective in Phase 1 clinical trials. (prevention.com)
• If you are in a clinical trial or compassionate use programme and need more information about your treatment, contact the doctor who is giving it to you. (europa.eu)
• And when new ideas are born, potentially life-saving clinical trials help our teams forge new paths for cancer treatment. (bestcare.org)
• Avita Medical announced the commencement of a randomized, controlled clinical trial of RECELL® in the treatment of deep partial-thickness (second-degree) burns in China. (biospace.com)
• From the moment of diagnosis, I serve as an objective and compassionate reference point for the patient and his/her loved ones during treatment and the years thereafter. (sutterhealth.org)
• Additionally, the MD Anderson researchers are developing a compassionate (home treatment) system for delivery of the anticancer treatment. (cdc.gov)
• 4 In contrast, antiviral treatment and prophylaxis are routinely recommended for ACF influenza outbreaks in Canada 5 and the United States of America 6 based mainly on the findings of observational studies 7-11 and a randomized controlled trial (RCT) of seasonal prophylaxis. (who.int)

Counsel1

• Trial Pro, P.A. delivers strategic advice and counsel to people in cities like Fruitland Park, South Apopka, Deltona, Kendall, South Fort Myers, Pelican Bay and across Florida. (trialpro.com)

Lawyer5

• Lynne Stewart, the 74-year-old veteran civil liberties lawyer serving a ten-year term on trumped up charges of aiding terrorism, was granted "compassionate release" this week and returned to her home in New York City. (wsws.org)
• Kurt D. Lloyd is a jury trial lawyer based in Chicago who represents victims of personal injury or wrongful death. (thenationaltriallawyers.org)
• At his funeral, Kurt said: 'his father's work ethic gave him the drive to succeed as a trial lawyer. (thenationaltriallawyers.org)
• Kurt has been nationally recognized as a jury trial lawyer by the American Association for Justice, which awarded him the Citation of Excellence medal. (thenationaltriallawyers.org)
• The trial judge, a senior member of the federal bench and an experienced trial lawyer himself, recognized that everyone benefits from this settlement, and that includes the taxpayers. (mysanantonio.com)

Grounds2

• Last summer, Judge Koeltl refused to set her free on compassionate grounds because the federal Bureau of Prisons had not yet agreed to the request. (wsws.org)
• Libyan Abdelbaset Ali Mohmed Al Megrahi was jailed for mass murder in 2001 but was returned to Tripoli in 2009 on compassionate grounds after doctors treating him for prostate cancer gave him an estimated three months to live. (channel4.com)

Summaries1

• Please use the search function below to find Plain Language Study Results Summaries for Pfizer-sponsored global clinical trials. (pfizer.com)

Remdesivir1

• Initiated by Gilead, the SIMPLE studies are 2 randomized, open-label, multi-center phase 3 clinical trials for remdesivir, in countries with high prevalence of COVID-19 infection. (pharmacytimes.com)

Enrolled in a clinical trial1

• Jessica Sultaire, 27, spent the past year enrolled in a clinical trial for an ovarian cancer drug. (prevention.com)

20181

• The company's aiming to start that trial in the second half of 2018, meaning it still might be a while before we start using viruses to treat our bacterial infections. (vpsfoundation.org)

Approval2

• Rush University Medical Center has submitted to the NIH to get approval to start a clinical trial in hopes this technique will be able to help people with all types of cancers. (foxla.com)
• The reports of clinical cardiac xenotransplant based on compassionate use FDA approval and renal xenotransplants to brain-dead humans have led to further considerations of clinical trials. (bvsalud.org)

Outbreak2

• With the COVID-19 outbreak, we were able to get a randomized trial up and running in a matter of weeks. (medscape.com)
• While we all are burdened by the COVID-19 outbreak, the festive season presents us with an opportunity to reflect on the blessings we all have - which always are more numerous than our trials. (who.int)

Preclinical2

• Among these, they identified 66 human proteins or host factors targeted by 69 existing FDA-approved drugs, drugs in clinical trials, and/or preclinical compounds. (medscape.com)
• RECENT FINDINGS: Long-term survival of life-supporting xenografts in preclinical models has led to discussion of clinical trials of xenotransplantation. (bvsalud.org)

Joining a clinical trial1

• If you or a loved one has cancer, you might consider joining a clinical trial. (cancer.net)

Conduct1

• As taxpayers whose money helps fund the work at NIH and the trials they conduct, we should be extremely proud. (medlineplus.gov)

Program2

• TB through a compassionate use program. (cdc.gov)
• The children were resistant to other anti-epileptic drugs and participated in this study through a compassionate use, off-label program. (nih.gov)

Researchers2

• Rather than stop a trial, discard the results and start over, researchers complete a trial anyway, knowing that there may be a better way to use the drug. (cancercommons.org)
• Doctors, or teams of researchers, can then think up the best combinations for each individual patient, and test them in small, fast, inexpensive (or free) virtual trials. (cancercommons.org)

Case6

• Attorney Jason Flores-Williams said that witnesses are scheduled to testify beginning at 9 a.m. on the days of the trial, but if the camping ban continues to be enforced, it's highly likely any witnesses who are homeless will not be able to make it - and that "makes it untenable for us to present this case at trial. (denverpost.com)
• It used to take six months to bring a case to trial in juvenile court and you just can't punish kids six months later," Early said. (masslive.com)
• Kurt believes that every client's case should be worked up as if the case will go to trial. (thenationaltriallawyers.org)
• By preparing every case for trial, the value of each client's case is maximized. (thenationaltriallawyers.org)
• for one thing, besides the PACE trial, other studies included also suffer from being open-label trials using a broad case definition and relying on subjective outcomes. (elsewhere.org)
• Great house trial lawyers got my husband the maximum amount for his case in a timely manner. (atltriallaw.com)

Advocate2

• Whether it's defending against criminal charges, or going after someone who caused you injury or monetary losses, Dan is a dedicated and compassionate advocate, former criminal prosecutor, and Top 40 Under 40 trial attorney who will do whatever it takes to get you the best results. (justia.com)
• Trial Pro P.A. is proud to advocate for workers compensation victims all over the state of Florida, including our office in Cape Coral . (trialpro.com)

Drugs7

• Doctors did clinical trials of drugs to prevent nausea and vomiting. (cancer.net)
• This is the result of clinical trials to develop anti-nausea drugs. (cancer.net)
• The problem with off-label use and compassionate use of drugs is interpretation of results. (medscape.com)
• WHO is encouraging adaptive trial designs that test candidate drugs in sequence and can be launched quickly. (medscape.com)
• Antipicornavirus compounds that reached clinical trials are scarce, and despite the fact that some of these drugs have demonstrated activity against certain picornavirus-associated conditions in humans, no specific antipicornavirus agent has yet been approved by the US Food and Drug Administration (FDA) ( 8 ). (cdc.gov)
• FDA chief Eric Domingo said a compassionate special permit (CSP) was only granted to eligible drugs -- those that had been registered in another country but not available locally or those being used in clinical trials. (gmanetwork.com)
• The Virtual Trial system should keep drug costs down, as it will take the vast majority of time and money out of the drug development process and break the monopolies currently preventing many new drugs from being developed. (cancercommons.org)

Exceptional1

• He has won by jury trial or settled exceptional cases which resulted in patient safety improvements. (thenationaltriallawyers.org)

Call3

• Call our compassionate staff today. (ehlinelaw.com)
• Call our Compassionate Use Information Line at (844) 287-3783 (CU-REQUEST) to provide preliminary information and discuss the potential options, including eligibility for any ongoing clinical trials. (gene.com)
• Luckily, the game also has an option in the settings called "Dogs Always Live", so if you want to avoid having to call into work for compassionate leave, you've got it covered. (jonhandhisdog.com)

Release4

• Josh's doctors had twice formally asked Chimerix, the North Carolina pharmaceutical company that makes brincidofovir, to release the drug under compassionate use. (harpers.org)
• let's see, if they are trying to get compassionate release or they ask about the first step back or how credits are applied to their time. (yahoo.com)
• Breaking: [Jen Shah's] judge denies compassionate release to her co-defendant. (realityblurb.com)
• And although her trial isn't for a few more months, co-defendant Derek has already been sentenced to 72 months in prison and five years of supervision upon his release, which he recently attempted to change due to his medical situation. (realityblurb.com)

Sickle1

• Recently, the largest lentiviral vector (LV)-mediated β-globin replacement gene therapy trial in sickle cell disease (SCD) was suspended due to a reported suspected unexpected serious adverse reaction (SUSAR) of acute myeloid leukemia (AML). (cell.com)

Study2

• A clinical trial is a research study that involves people. (cancer.net)
• PURPOSE OF REVIEW: The aim of this study was to highlight recent progress in xenotransplantation and discuss the remaining obstacles/steps before the FDA is likely to approve a clinical trial. (bvsalud.org)

Results1

• With COVID-19, we've seen more changes to clinical trial practices than at any other time in my career," says David Gerber, M.D. , a professor of internal medicine at UTSW, associate director of clinical research in the Simmons Cancer Center , and first author of an article on the survey results that were published online this month in the Journal of the National Comprehensive Cancer Network . (newswise.com)

Settlement6

• Our lawyers in Culver City get the best possible settlement, or we go to trial. (ehlinelaw.com)
• It would have been reckless malpractice for us as the state's lawyers to pass up this settlement opportunity and the opportunity to eliminate the uncertainty that every trial presents. (mysanantonio.com)
• In light of plaintiff's eve-of-trial settlement offer, no interest would have been served by going forward with a very expensive trial. (mysanantonio.com)
• Her privacy needs and rights make settlement a compassionate resolution, sparing her the need to reveal intimate health details at trial. (mysanantonio.com)
• The state has no interest in going to trial, at greater expense than the cost of a settlement, in order to destroy a life and lay bare a person's health records through the likely media coverage at trial. (mysanantonio.com)
• Their legal team handles all aspects of personal injury cases for its clients, from initial filing to settlement negotiations and trial proceedings. (lasvegasinquirer.com)

Jury5

• She was found guilty in February 2005 after a seven-month trial and jury deliberations that stretched over 13 days, in which a number of jurors reportedly held out for many days for acquittal. (wsws.org)
• Kurt works tirelessly to protect and advance his clients right to a trial by jury. (thenationaltriallawyers.org)
• With over 30 years of experience and 70 plus jury trials, he has won more than $355 million in jury verdicts and settlements from insurance companies and corporations to help his injured clients recover. (thenationaltriallawyers.org)
• After prosecuting 50 civil jury trials, the prestigious American Board of Trial Advocates invited Kurt to become a member. (thenationaltriallawyers.org)
• He wrote the book to help young trial lawyers representing injured clients understand how to select a jury in Illinois courts. (thenationaltriallawyers.org)

Involve1

• Clinical trials involve volunteers. (cancer.net)

Attorneys4

• The attorneys suing Denver over its sweeps of homeless encampments asked a federal judge on Monday to suspend enforcement of the city's camping ban ahead of, and during, next month's scheduled trial in the class-action lawsuit. (denverpost.com)
• The attorneys are asking for enforcement to be suspended beginning one week prior to the trial, which is scheduled for March 12 and expected to last 10 days. (denverpost.com)
• Anyone hiring our great trial attorneys will have more respect from parties and courts. (ehlinelaw.com)
• At the Amaro Law Firm, clients will benefit from experienced trial attorneys who have successfully navigated hundreds of cases over the years. (lasvegasinquirer.com)

Work2

• Plotkin had only recently heard of compassionate use, but he was so infuriated by Chimerix's refusal that he went to work instantly. (harpers.org)
• While a trial against Cardinal Joseph Zen is getting underway in China , the Holy See continues to work toward the renewal of the Sino-Vatican agreement for the appointment of bishops. (aciafrica.org)

Nurses2

• A survey of UTSW clinical cancer research professionals found that most clinical trial coordinators, managers, and nurses report positive experiences with these COVID-related adjustments. (newswise.com)
• Ninety-four responded to the survey, including administrative professionals who coordinate trial logistics and finances, research nurses, research managers and coordinators, and data specialists. (newswise.com)

Murder5

• If you want to dry the roots of aggression and murder, let's put those behind the recent wars in the Persian Gulf and the Middle East, on trial and sentence them together. (juancole.com)
• Australian murder trial - woman claims she assisted her boyfriends suicide. (blogspot.com)
• A murder trial in Australia shows how assisted suicide techniques can be a cover for murder. (blogspot.com)
• In the murder trial in the death of Dunbar, Darcy is arguing that she did not murder Dunbar, her boyfriend of three years, but admits to assisting his suicide. (blogspot.com)
• A boy's brutal murder and the public trials of his guardians and social workers prompt questions about the system's protection of vulnerable children. (sbcasa.org)

People5

• They do clinical trials to prevent and treat late effects in people with cancer. (cancer.net)
• For example, a clinical trial might be for people over 50. (cancer.net)
• Does a "compassionate city" let people sleep outside? (denverpost.com)
• We believe the trial poses an unjustifiable level of risk of serious harm and death to the most vulnerable people in our communities, which will in turn have a devastating impact on their whānau. (mentalhealth.org.nz)
• It may be years before we see this come to pass, but God will surprise us at the heart connections we will make with people facing similar trials. (specialhopemoms.com)

Therapies1

• How might your Virtual Trial approach speed the process toward either validating or invalidating potential therapies for glioblastoma? (cancercommons.org)

Time4

• Early said the trial time is now down to a few weeks in the juvenile court. (masslive.com)
• On the eve of the trial, Capps agreed the state could disclose she had pre-existing medical conditions that were being treated with medication that affected her job performance at the time of the missed appeal. (mysanantonio.com)
• A compassionate local carer will visit your loved one for a few hours at a time. (berkeleyhomehealth.com)
• You might be having a tough time sleeping, noticing some scary thoughts popping up, and just getting through each day is a trial. (counsellingbc.com)

Phase II trial1

• Phase II Trial of Trametinib and Panitumumab in RAS/RAF Wild Type Metastatic Colorectal Cancer. (cdc.gov)

Disease1

• Clinical trials also help doctors learn how to prevent disease or treat symptoms and side effects. (cancer.net)

Implementation2

• As a member of Stanford s Eastern Cooperative Oncology Group trials effort, Dr. Pinto is involved in the implementation and development of a variety of clinical trials at Stanford and the Palo Alto Veterans Affairs Medical Center. (stanford.edu)
• We feel there has been a lack of transparency from the New Zealand Police to justify the implementation of the trial and the decision-making process that led to its introduction. (mentalhealth.org.nz)

Tumors1

• The following are recent clinical trials including desmoid tumors. (dtrf.org)

Diagnosis1

• It makes the PD diagnosis small in comparison to the trials and tribulations of those I serve. (parkinson.org)

Patient2

• patient and compassionate lover of Christ Crucified! (lordcalls.com)
• So, if a patient desires entry into a formal trial, I propose they be given access to the registry to pick the most promising trials. (cancercommons.org)

Find4

• Doctors do clinical trials to find new ways to prevent cancer, reduce people's risk of cancer, or find it early. (cancer.net)
• That makes it harder to get witnesses to trial, she said, because organizers such as herself are unable to find them and to bring them to the trial to testify. (denverpost.com)
• I'm concerned that the authorities will find out new information but not tell the public because it would expose a flawed trial. (channel4.com)
• I suppose it's what everyone would hope to find in any health professional but I can't imagine one always does-this super-intelligent workhorse who is also so human and compassionate. (medlineplus.gov)

Great1

• We had a great trial team and they were ready for the trial. (mysanantonio.com)

Learn1

• Use our guide to learn which trials are right for you! (clinicaltrialsgps.com)

Research1

• The fellow will have the opportunity to develop their own research projects and/or contribute to existing trials. (henryford.com)

Make1

• My goal today is to show that compassionate conservatism is not an easy slogan, that the practice of it is very hard, that only discernment and courage will make it a reality. (heritage.org)