Comparative Effectiveness Research
Conduct and synthesis of systematic research comparing interventions and strategies to prevent, diagnose, treat, and monitor health conditions. The purpose of this research is to inform patients, providers, and decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. (hhs.gov/recovery/programs/cer/draftdefinition.html accessed 6/12/2009)
United States Agency for Healthcare Research and Quality
An agency of the PUBLIC HEALTH SERVICE established in 1990 to "provide indexing, abstracting, translating, publishing, and other services leading to a more effective and timely dissemination of information on research, demonstration projects, and evaluations with respect to health care to public and private entities and individuals engaged in the improvement of health care delivery..." It supersedes the National Center for Health Services Research. The United States Agency for Health Care Policy and Research was renamed Agency for Healthcare Research and Quality (AHRQ) under the Healthcare Research and Quality Act of 1999.
American Recovery and Reinvestment Act
Patient-Centered Care
Patient Protection and Affordable Care Act
An Act prohibiting a health plan from establishing lifetime limits or annual limits on the dollar value of benefits for any participant or beneficiary after January 1, 2014. It permits a restricted annual limit for plan years beginning prior to January 1, 2014. It provides that a health plan shall not be prevented from placing annual or lifetime per-beneficiary limits on covered benefits. The Act sets up a competitive health insurance market.
Observational Study as Topic
Electronic Health Records
Media that facilitate transportability of pertinent information concerning patient's illness across varied providers and geographic locations. Some versions include direct linkages to online consumer health information that is relevant to the health conditions and treatments related to a specific patient.
Evidence-Based Medicine
An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)
Research Design
Translational Medical Research
Therapies, Investigational
Health Care Reform
Innovation and improvement of the health care system by reappraisal, amendment of services, and removal of faults and abuses in providing and distributing health services to patients. It includes a re-alignment of health services and health insurance to maximum demographic elements (the unemployed, indigent, uninsured, elderly, inner cities, rural areas) with reference to coverage, hospitalization, pricing and cost containment, insurers' and employers' costs, pre-existing medical conditions, prescribed drugs, equipment, and services.
Observation
The act of regarding attentively and studying facts and occurrences, gathering data through analyzing, measuring, and drawing conclusions, with the purpose of applying the observed information to theoretical assumptions. Observation as a scientific method in the acquisition of knowledge began in classical antiquity; in modern science and medicine its greatest application is facilitated by modern technology. Observation is one of the components of the research process.
Outcome Assessment (Health Care)
Randomized Controlled Trials as Topic
Outcome and Process Assessment (Health Care)
Medical Informatics
Organizational Objectives
Health Policy
Decision Making
Cost-Benefit Analysis
A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.
Data Collection
Patient Participation
Diffusion of Innovation
Delivery of Health Care
Data Interpretation, Statistical
Medicare
Federal program, created by Public Law 89-97, Title XVIII-Health Insurance for the Aged, a 1965 amendment to the Social Security Act, that provides health insurance benefits to persons over the age of 65 and others eligible for Social Security benefits. It consists of two separate but coordinated programs: hospital insurance (MEDICARE PART A) and supplementary medical insurance (MEDICARE PART B). (Hospital Administration Terminology, AHA, 2d ed and A Discursive Dictionary of Health Care, US House of Representatives, 1976)
Treatment Outcome
Clinical Trials as Topic
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Neoplasms
Matched-Pair Analysis
Quality-Adjusted Life Years
Financial Support
Tobacco Industry
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
The policies and politics of creating a comparative clinical effectiveness research center. (1/390)
(+info)'Marginal medicine': targeting comparative effectiveness research to reduce waste. (2/390)
(+info)Developing a policy for second-generation antipsychotic drugs. (3/390)
(+info)Comparative effectiveness research for antipsychotic medications: how much is enough? (4/390)
(+info)Does telemonitoring of patients--the eICU--improve intensive care? (5/390)
(+info)Measurement of and reward for efficiency In California's pay-for-performance program. (6/390)
(+info)Is it time to reexamine the patent system's role in spending growth? (7/390)
(+info)Gemcitabine for the treatment of metastatic breast cancer. (8/390)
(+info)
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Comparative Effectiveness Research
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Joel M Gelfand, MD, MSCE | CCEB
Developing Methods to Estimate and Address Errors in Studies Using Electronic Health Record Data | PCORI
UC Irvine gets major funding to study prevention of drug-resistant staph infections | UC Irvine Health | Orange County, CA
Meetings - Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct
Robin Hines, Ph.D., M.P.H. - College of Medicine
Department of Medicine Grand Rounds - Bermuda Hospitals Board
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Marc Boutin, JD
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University of Pittsburgh School of Medicine
... as well as a certificate in comparative effectiveness research.[27] Interdisciplinary Biomedical Science Graduate Program[edit] ... comparative effectiveness research; immunology and immunological approaches to cancer; and cancer virology. The school is also ... and comparative effectiveness research. An innovative system of Web-based learning portfolios facilitates learner-mentor ... Research[edit]. The University of Pittsburgh School of Medicine is a leading center for medical research. Of the medical ...
Atrial fibrillation
Comparative Effectiveness Review No. 123. AHRQ Publication No. 13-EHC113-EF. Rockville, MD: Agency for Healthcare Research and ... Many issues should be considered related to their comparative effectiveness, including the cost of DOACs, risk of stroke, risk ... "BMJ (Clinical Research Ed.). 348: g2116. doi:10.1136/bmj.g2116. PMC 4688652. PMID 24733535.. ... "BMJ (Clinical Research Ed.). 532: h7013. doi:10.1136/bmj.h7013. PMC 5482349. PMID 26786546.. ...
Adherence (medicine)
Medication Adherence Interventions: Comparative Effectiveness. Closing the Quality Gap: Revisiting the State of the Science. ... Office of Behavior and Social Sciences Research. "Adherence Research Network". U.S. National Institutes of Health. Archived ... US NIH Office of Behavior and Social Sciences Research (2008). "Framework for adherence research and translation: a blueprint ... Rockville, MD: Agency for Healthcare Research and Quality. September 2012. *^ a b Rifaat Nizar; Abdel-Hady Elham; Hasan Ali A ( ...
Posttraumatic stress disorder
"Comparative Effectiveness Reviews (92). Rockville, MD: US Agency for Healthcare Quality and Research. PMID 23658937. Archived ... Agency for Healthcare Research and Quality (US). PMID 23658936.. *^ Feldner MT, Monson CM, Friedman MJ (January 2007). "A ... Journal of Rehabilitation Research and Development. 49 (5): 703-15. doi:10.1682/JRRD.2011.09.0183. PMID 23015581. Archived (PDF ... Progress in Brain Research. 167. pp. 287-91. doi:10.1016/S0079-6123(07)67025-3. ISBN 978-0-444-53140-7. . PMID 18037027.. ...
Consumers United for Evidence-based Healthcare
"Consumer involvement in systematic reviews of comparative effectiveness research". Health Expect. 16 (4): 323-337. doi:10.1111/ ... health professional organizations can request consumer representatives for their research/research implementation projects and ... Reinventing medical research (1st ed.). Durham, NC: Duke University Press Books. ISBN 978-0822318163.. ... Diana Zuckerman (President of the National Center for Health Research and The Cancer Prevention and Treatment Fund) ...
Clostridioides difficile infection
AHRQ Comparative Effectiveness Reviews.: vi, 1. PMID 27148613.. *^ a b c d Nelson RL, Suda KJ, Evans CT (March 2017). " ... Research[edit]. *As of 2019, vaccine candidates providing immunity against C. difficile toxin A and C. difficile toxin B have ... "Comparative effectiveness of Clostridium difficile treatments: a systematic review". Annals of Internal Medicine. 155 (12): 839 ... Research has studied whether the appendix has any importance in C. difficile. The appendix is thought to have a function of ...
Posttraumatic stress disorder
"Comparative Effectiveness Reviews (92). Rockville, MD: US Agency for Healthcare Quality and Research. PMID 23658937. Archived ... Agency for Healthcare Research and Quality (US). PMID 23658936.. *^ Feldner MT, Monson CM, Friedman MJ (January 2007). "A ... Progress in Brain Research. 167. pp. 287-91. doi:10.1016/S0079-6123(07)67025-3. ISBN 978-0-444-53140-7. . PMID 18037027.. ... Progress in Brain Research. 167. pp. 151-69. doi:10.1016/S0079-6123(07)67011-3. ISBN 9780444531407. . PMID 18037013.. ...
Antidepressant discontinuation syndrome
Comparative Effectiveness Reviews. Rockville, MD: Agency for Healthcare Research and Quality. Byatt N, Deligiannidis KM, ... An Update of the 2007 Comparative Effectiveness Review (Report). ... to evaluate all the research available prior to 2004. The group ...
Osteoarthritis
An Update of the 2006 Comparative Effectiveness Review". Comparative Effectiveness Reviews. 38. Agency for Healthcare Research ... The effectiveness of glucosamine is controversial. Reviews have found it to be equal to or slightly better than placebo. A ... The effectiveness of injections of platelet-rich plasma is unclear; there are suggestions that such injections improve function ... Further research is needed to determine if balnotherapy for osteoarthritis (mineral baths or spa treatments) improves a ...
Clinical trials on glucosamine and chondroitin
Comparative Effectiveness Reviews. Rockville: Agency for Healthcare Research and Quality. PMID 22091473.[page needed] Rovati LC ... An Update of the 2006 Comparative Effectiveness Review [Internet]". Agency for Healthcare Research and Quality (US). PMID ... The Osteoarthritis Research Society International recommends that glucosamine be discontinued if no effect is observed after ... Critical review of research evaluating glucosamine-based nutraceuticals for treatment of joint pain and degenerative joint ...
Diabetes medication
An Update" (PDF). Comparative Effectiveness Review. number 27 (AHRQ Pub. No. 11-EHC038-1). Archived from the original (PDF) on ... Research, Center for Drug Evaluation and. "Drug Safety and Availability - Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors". ... "Comparative effectiveness and safety of medications for type 2 diabetes: An update including new drugs and 2-drug combinations ... "The Oral Diabetes Drugs Treating Type 2 Diabetes Comparing Effectiveness, Safety, and Price" (PDF). Archived (PDF) from the ...
Doxepin
AHRQ Comparative Effectiveness Reviews. Agency for Healthcare Research and Quality (US). PMID 26844312. Eschler DC, Klein PA ( ... Sustained effectiveness without apparent tolerance was demonstrated in clinical studies of up to 12 weeks duration. This ... Based on in vitro research, the major enzymes involved in the metabolism of doxepin are the cytochrome P450 enzymes CYP2D6 and ... The H1 receptor antagonism of doxepin is responsible for its hypnotic effects and its effectiveness in the treatment of ...
Kidney cancer
AHRQ Comparative Effectiveness Reviews. Rockville (MD): Agency for Healthcare Research and Quality (US). PMID 26866209. Motzer ... "Kidney cancer statistics". Cancer Research UK. Retrieved 27 October 2014.. ...
Insomnia
AHRQ Comparative Effectiveness Reviews. Rockville (MD): Agency for Healthcare Research and Quality (US). PMID 26844312. Conn DK ... AHRQ Comparative Effectiveness Reviews. Rockville (MD): Agency for Healthcare Research and Quality (US). PMID 22132426. ... Mitchell MD, Gehrman P, Perlis M, Umscheid CA (May 2012). "Comparative effectiveness of cognitive behavioral therapy for ... The effectiveness and safety of alternative medicine is unclear. Between 10% and 30% of adults have insomnia at any given point ...
Urinary incontinence
Diagnosis and Comparative Effectiveness". AHRQ Comparative Effectiveness Reviews. Agency for Healthcare Research and Quality ( ... Research projects that assess the efficacy of anti-incontinence therapies often quantify the extent of urinary incontinence. ... The effectiveness of different therapeutic approaches to treating urinary incontinence is not well studied for some medical ... Wang W, Huang QM, Liu FP, Mao QQ (December 2014). "Effectiveness of preoperative pelvic floor muscle training for urinary ...
Low back pain
AHRQ Comparative Effectiveness Reviews. Rockville (MD): Agency for Healthcare Research and Quality (US). PMID 26985522. van ... Seco J, Kovacs FM, Urrutia G (October 2011). "The efficacy, safety, effectiveness, and cost-effectiveness of ultrasound and ... Lumbar traction lacks effectiveness as an intervention for radicular low back pain. It is also unclear whether lumbar supports ... There has been little research that supports the use of lumbar extension machines and thus they are not recommended. There is ...
Eclectic psychotherapy
AHRQ Comparative Effectiveness Reviews. Rockville (MD): Agency for Healthcare Research and Quality (US). OCLC 845095216. PMID ... The decision to use or not use each form may be based upon therapist preference, patient preference or effectiveness for ... There is a great emphasis on using clinical research and prior clinical knowledge in determining how to move forward with ... The use of different therapeutic approaches will be based on the effectiveness in resolving the patient's problems, rather than ...
Treatments for PTSD
AHRQ Comparative Effectiveness Review. Rockville (MD): Agency for Healthcare Research and Quality (US). doi:10.23970/ ... Initial research on MDMA-assisted psychotherapy has shown the treatment to be efficacious and well tolerated. For example, in a ... While it is not yet accepted medical treatment, there are often studies being done to test its effectiveness. Usually, it is ... "Long-term Nabilone Use: A Review of the Clinical Effectiveness and Safety". CADTH Rapid Response Reports. Oct 2015. PMID ...
Transcranial magnetic stimulation
AHRQ Comparative Effectiveness Reviews. Agency for Healthcare Research and Quality. PMID 22091472. Cite journal requires , ... "Transcranial Magnetic Stimulation Cites Influence of New England Comparative Effectiveness Public Advisory Council (CEPAC)". ... The New England Comparative Effectiveness Public Advisory Council (CEPAC). Archived from the original (PDF) on 2013-12-11. ... and roadmap for future research". Autism Research. 9 (2): 184-203. doi:10.1002/aur.1567. PMC 4956084. PMID 26536383. Nizard J, ...
Cleft lip and cleft palate
AHRQ Comparative Effectiveness Reviews. Rockville (MD): Agency for Healthcare Research and Quality (US). PMID 28817250. ... Research has shown that during the early preschool years (ages 3-5), children with cleft lip or cleft palate tend to have a ... There is research dedicated to the psychosocial development of individuals with cleft palate. A cleft palate/lip may impact an ... The research found that PHF8 encodes for a histone lysine demethylase, and is involved in epigenetic regulation. The catalytic ...
Picture Exchange Communication System
Comparative Effectiveness Review No. 26. Agency for Healthcare Research and Quality (AHRQ) Publication No. 11-EHC029-EF. Ganz, ... Research in Developmental Disabilities, 33(2), 406-418. Flippin, M., Reszka, S., et al. (2010). Effectiveness of the Picture ... Research indicates that "PECS is probably best used as an initial intervention to teach manding and the basic elements of what ... Research & Practice for Persons with Severe Disabilities, 33(1-2), 13-24. Conklin, C. G. (2011-03-01). Effects of implementing ...
Management of depression
Comparative Effectiveness Review Number 33. (Prepared by RTI International-University of North Carolina (RTI-UNC) Evidence- ... "National Institute of Mental Health Treatment of Depression Collaborative Research Program. General effectiveness of treatments ... August 2016). "Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and ... A meta-analysis examined the effectiveness of psychotherapy for depression across ages from younger than 13 years to older than ...
Patient-reported outcome
Journal of Comparative Effectiveness Research. 3 (5): 523-531. doi:10.2217/cer.14.41. ISSN 2042-6313. PMID 25350803. Donath, ... Quality of Life Research. 2008; 17: 1297-302. Doward LC, McKenna SP, Defining Patient-Reported Outcomes. Value in Health. 2004 ... The use of digitized PROs, or electronic patient-reported outcomes (ePROs), is on the rise in today's health research setting. ... Bottomley, Andrew; Aaronson, Neil K. (Nov 10, 2007). "International perspective on health-related quality-of-life research in ...
Perioperative
Journal of Comparative Effectiveness Research. 4 (6): 615-650. doi:10.2217/cer.15.43. ISSN 2042-6305. PMID 26346494. AORN - ...
Advance care planning
Journal of Comparative Effectiveness Research. 4 (6): 615-650. doi:10.2217/cer.15.43. ISSN 2042-6305. PMID 26346494. Silveira, ... A research conducted in Switzerland with people aged 71 to 80 showed that better knowledge on advance care planning ...
Adherence (medicine)
Medication Adherence Interventions: Comparative Effectiveness. Closing the Quality Gap: Revisiting the State of the Science. ... US NIH Office of Behavior and Social Sciences Research (2008). "Framework for adherence research and translation: a blueprint ... Office of Behavior and Social Sciences Research. "Adherence Research Network". U.S. National Institutes of Health. Archived ... The effectiveness of two-way email communication between health care professionals and their patients has not been adequately ...
Expenditures in the United States federal budget
Examples include: comparative effectiveness research; independent review panels; modifying doctor incentives to focus on better ... Congressional Research Service. Retrieved November 27, 2012. U.S. Congressional Budget Office, An Analysis of the President's ... Slightly more than half of federal research and development funds go to the Department of Defense and thus overlaps with ... Funding for science research and development is mainly funded through discretionary funding through agencies such as the ...
Vinpocetine
Schmidt J (1990). "Comparative studies on the anticonvulsant effectiveness of nootropic drugs in kindled rats". Biomedica ... Epilepsy Research. 96 (3): 257-66. doi:10.1016/j.eplepsyres.2011.06.006. PMID 21737246.. ... Brain Research. 909 (1-2): 59-67. doi:10.1016/S0006-8993(01)02621-X. PMID 11478921.. ...
Alternative medicine
Funding for research is also sparse making it difficult to do further research for effectiveness of CAM.[175] Most funding for ... Comparative study of placebo-controlled trials of homoeopathy and allopathy", The Lancet, 366 (9487): 726-32, doi:10.1016/S0140 ... Use of health and research resources. Research into alternative therapies has been criticized for "...diverting research time, ... Research into alternative therapies often fails to follow proper research protocols (such as placebo-controlled trials, blind ...
Acne
Research[edit]. Efforts to better understand the mechanisms of sebum production are underway. This research aims to develop ... Benzoyl peroxide (BPO) is a first-line treatment for mild and moderate acne due to its effectiveness and mild side-effects ( ... Levy LL, Zeichner JA (October 2012). "Management of acne scarring, part II: a comparative review of non-laser-based, minimally ... Rates appear to be lower in rural societies.[22] While some research has found it affects people of all ethnic groups,[175] ...
Hematopoietic stem cell transplantation
Research[edit]. HIV[edit]. In 2007, a team of doctors in Berlin, Germany, including Gero Hütter, performed a stem cell ... March 2013). "Cost-effectiveness of Single-Use Technologies for Commercial Cell Therapy Manufacture". Am. Pharm. Rev.: 40. ISSN ... 2005). "Comparative outcome of nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation for patients ... However, recent research has shown that such lineage infidelity does not occur as a normal phenomenon[citation needed]. ...
Chiropractic
Menke JM (January 2014). "Do Manual Therapies Help Low Back Pain?: A Comparative Effectiveness Meta-Analysis". Spine (Meta- ... Chiropractic in the United States: Training, Practice, and Research. Rockville, MD: Agency for Health Care Policy and Research ... Chiropractic in the United States: Training, Practice, and Research. Rockville, MD: Agency for Health Care Policy and Research ... A 2006 systematic cost-effectiveness review found that the reported cost-effectiveness of spinal manipulation in the United ...
Occupational health psychology
... and evaluate the effectiveness of such interventions.[36] The research methods used in OHP are similar to those used in other ... Research topics[edit]. Important theoretical models in OHP research[edit]. Three influential theoretical models in OHP research ... Research methods[edit]. Main article: List of psychological research methods. The main purpose of OHP research is to understand ... Qualitative research methods[edit]. Qualitative research methods include interviews,[50][51] focus groups,[52] and self- ...
Wheelchair
Ferguson-Pell, M., Cardi, M. D. Prototype Development and Comparative Evaluation of Wheelchair Pressure Mapping System. ... Ferguson-Pell, M. (1992) Choosing a Wheelchair System. Journal of Rehabilitation Research and Development. p.49. ... Prior to 1970, little was known about the effectiveness of wheelchair cushions and there was not a clinical method of ... "Research Device to Preproduction Prototype: A Chronology" (PDF). JRRD. 30 (4): 436-42. ISSN 0748-7711 ...
Data compression
... due to recent theoretical analysis showing a comparative lack of effectiveness of such methods.[23] ... Nucleic Acids Research. 40 (20): e159. doi:10.1093/nar/gks709. PMC 3488212. PMID 22844100.. CS1 maint: Multiple names: authors ... International Journal of Scientific & Engineering Research. 3 (3): 2. Retrieved 6 March 2013.. ... Lossy data compression schemes are designed by research on how people perceive the data in question. For example, the human eye ...
Moclobemide
... research is required to determine this.[8] Moclobemide has also been demonstrated in a single dose research study to possess ... Moclobemide has demonstrated effectiveness and efficacy in the treatment and management of major depressive disorder,[18] with ... Dingemanse J, Berlin I, Payan C, Thiede HM, Puech AJ (1992). "Comparative investigation of the effect of moclobemide and ... The effectiveness of moclobemide in agitated depression is equivalent to that of imipramine and sedative antidepressants such ...
Sales promotion
Journal of Consumer Research. 34 (2): 162-173. doi:10.1086/518526.. *^ a b c d e McKechnie, Sally (2012). "Effects Of Discount ... Framing In Comparative Price Advertising". European Journal of Marketing. 46 (11/12): 1501-1522. doi:10.1108/03090561211259952. ... and to take advantage of opportunities that are revealed by market research. It is made up of activities, both outside and ...
Bioarchaeology
These changes were widely used to study activity-patterns, but research has shown that processes associated with aging have a ... Michopoulou, E.; Nikita, E.; Henderson, C. Y. (2016-01-01). "A test of the effectiveness of the Coimbra method in capturing ... Journal of Comparative Human Biology International Journal of Paleopathology Bioarchaeology of the Near East Other ... Sillen, Andrew; Sealy, Judith C.; Nikolaas; van der Merwe, J. (1989). "Chemistry and Paleodietary Research: No More Easy ...
肥胖症 - 维基百科,自由的百科全书
BMJ (Comparative Study). 2008, 337: a494 [2016-01-20]. PMC 2500200. PMID 18617488. doi:10.1136/bmj.a494. ï¼ˆåŽŸå§‹å†…å®¹å˜æ¡£äºŽ2009-02-22).. ... BMJ (Clinical research ed.) (Meta-analysis). 2012-05-16, 344: e2088. PMC 3355191. PMID 22596383. doi:10.1136/bmj.e2088.. ... The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003-2012. JAMA Surgery (Meta ... Comparative Study). 2008-02, 5 (2): e29 [2016-01-20]. PMC 2225430. PMID 18254654. doi:10.1371/journal.pmed.0050029. ï¼ˆåŽŸå§‹å†…å®¹å˜æ¡£äºŽ ...
Recidivism
For example, research shows that treatment effectiveness should include cognitive-behavioral and social learning techniques of ... "International Journal of Offender Therapy and Comparative Criminology. 48 (2): 133-48. doi:10.1177/0306624X03259472. PMID ... Some people may view such a program as providing privileges for those considered undeserving.[original research?] A judge in ... Most research regarding recidivism indicates that those ex-inmates that obtain employment after release from prison tend to ...
Steel
Prawoto, Yunan (2013). Integration of Mechanics into Materials Science Research: A Guide for Material Researchers in Analytical ... Bringas, John E. (2004). Handbook of Comparative World Steel Standards: Third Edition (PDF) (3rd. ed.). ASTM International. p. ... steel uses a specific type of strain to increase the effectiveness of work hardening on the alloy.[64] ... Verein Deutscher Eisenhüttenleute (Ed.). Steel - A Handbook for Materials Research and Engineering, Volume 1: Fundamentals. ...
Alzheimerova bolest
2,0 2,1 2,2 2,3 2,4 2,5 2,6 2,7 2,8 Burns, A; Iliffe, S (5 February 2009). "Alzheimer's disease.". BMJ (Clinical research ed.) ... Language Performance in Alzheimer's Disease and Mild Cognitive Impairment: a comparative review. Journal of Clinical and ... Consumer Reports; Drug Effectiveness Review Project. Evaluating Prescription Drugs Used to Treat: Alzheimer's Disease Comparing ... Archives of medical research 43 (8): 677-85. PMID 23178565. doi:10.1016/j.arcmed.2012.11.009. ...
Chronic obstructive pulmonary disease
"COPD Research and Practice. 3. doi:10.1186/s40749-017-0024-y.. *^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa Vestbo ... The effectiveness of alpha-1 antitrypsin augmentation treatment for people who have alpha-1 antitrypsin deficiency is unclear.[ ... "Comparative efficacy of long-acting muscarinic antagonist monotherapies in COPD: a systematic review and network meta-analysis ... Research[edit]. See also: COPD: Journal of Chronic Obstructive Pulmonary Disease. Mass spectrometry is being studied as a ...
Lesbian
National Congress of American Indians Policy Research Center.. *^ Estrada, Gabriel (2011). "Two Spirits, Nádleeh, and LGBTQ2 ... 2001). "Chapter Ten: Comparative Sapphism, Sharon Marcus". The Literary Channel: The Inter-National Invention of the Novel (PDF ... The Latin American lesbian movement has been the most active in Mexico, but has encountered similar problems in effectiveness ... "American Indian Culture and Research Journal. 35 (4): 167-190. doi:10.17953/aicr.35.4.x500172017344j30.. [permanent dead link] ...
World Bank
"Association of Research Libraries. Retrieved 11 July 2012.. *^ Vasdev, Samhir (18 April 2016). "Why the World Bank endorses the ... "Boston College International and Comparative Law Review. 25 (1): 125-158. Retrieved 25 April 2012.. ... Partners work together to put international principles for aid effectiveness and development cooperation into practice in the ... The World Bank hosts the Open Knowledge Repository (OKR)[58] as an official open access repository for its research outputs and ...
Urinary tract infection
"Comparative effectiveness of antibiotics for uncomplicated urinary tract infections: network meta-analysis of randomized trials ... Some research suggests that cranberry (juice or capsules) may decrease the number of UTIs in those with frequent infections.[53 ... Franco, AV (December 2005). "Recurrent urinary tract infections". Best Practice & Research. Clinical Obstetrics & Gynaecology. ... Some women have UTIs that keep coming back in pregnancy and currently there is not enough research on how to best treat these ...
Audio therapy
Experimental Brain Research, Vol. 196, No. 4, 2009, pp565-571. Holmes, E. A., and Mathews, A., Mental imagery in emotion and ... Baird, C. L., and Sands, L., A pilot study of the effectiveness of guided imagery with progressive muscle relaxation to reduce ... A systematic review and meta-analysis of comparative outcome studies. Psychological Medicine, Vol. 40, No. 12, 2010, pp1943- ... Meador, K. S., Fishkin, A. S., and Hoover, M., Research-based strategies and programs to facilitate creativity. In Fishkin, A. ...
List of countries with universal health care
2010). "International comparison of comparative effectiveness research in five jurisdictions: insights for the US". ... Leichter, Howard M. (1979). A comparative approach to policy analysis: health care policy in four nations. Cambridge: Cambridge ... Finally, industry coverage covers the production and distribution of healthcare products for research and development. The ... Initially successful at combating infectious diseases, the effectiveness of the socialized model declined with underinvestment ...
Dysthymia
"Comparative effectiveness of continuation and maintenance treatments for persistent depressive disorder in adults". The ... Research shows that 1 in 4 of those who switch medications get better results regardless of whether the second medication is an ...
Paleontology
"Integrative and Comparative Biology. 43 (1): 166-177. doi:10.1093/icb/43.1.166. PMID 21680421. Archived from the original on ... This change in the atmosphere increased their effectiveness as nurseries of evolution.[57] While eukaryotes, cells with complex ... Sometimes the smoking gun is discovered by a fortunate accident during other research. For example, the discovery by Luis ... "HOMO: Journal of Comparative Human Biology. 52 (1): 3-58. doi:10.1078/0018-442X-00019.. ...
Low-carbohydrate diet
New York: The Rockefeller Institute for Medical Research.. *^ Another publication of similar regimen was Hill LW, Eckman RS ( ... There is little evidence for the effectiveness of low-carbohydrate diets for people with type 1 diabetes.[1] For certain ... 2018). "Comparative effects of different dietary approaches on blood pressure in hypertensive and pre-hypertensive patients: A ... Much of the research comparing low-fat vs. low-carbohydrate dieting has been of poor quality and studies which reported large ...
Progressive supranuclear palsy
... in helping to guide future research concerning the effectiveness of balance and gait training programs in the management of PSP ... Buée L, Delacourte A (October 1999). "Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal ... Internationally, several organizations serve the needs of patients with PSP and their families and support research. ... and currently the majority of research on the subject consists of case reports involving only a small number of patients. ...
Common factors theory
Carr, Alan (2008). What works with children, adolescents, and adults: a review of research on the effectiveness of ... Frank, Jerome D; Frank, Julia (1991) [1961]. Persuasion and healing: a comparative study of psychotherapy (3rd ed.). Baltimore ... Empirical research[edit]. Research by Laska et al. (2014)[35] Factor. % of Variability. in Outcome ... "Psychotherapy: Theory, Research, Practice, Training. 44 (3): 239-299.. *^ a b Frank & Frank 1991; the legacy of Frank's work is ...
Learned industriousness
Journal of Research in Psychology, 26, 258-272. *^ a b Fisher, C. D. & Noble, C. S. (2004). A within-person examination of ... Journal of Comparative and Physiological Psychology, 63, 28-33. *^ a b Eisenberger, R., Park, D. C., & Frank, M. (1976). ... Daniels, A. C., & Daniels, J. E. (2006). Performance Management: Changing Behavior that Drives Organizational Effectiveness. ... further research should be done to provide evidence for or against its existence. This research could be useful for personnel ...
Medication
This was ascribed to the fact that every new drug competes in effectiveness with every other drugs known so far, other economic ... As of 2008, the United States is the leader in medical research, including pharmaceutical development. U.S. drug prices are ... Fonseca, Massard da; Shadlen, Kenneth C. (20 April 2017). "Promoting and regulating generic medicines: Brazil in comparative ... It includes pre-clinical research (microorganisms/animals) and clinical trials (on humans) and may include the step of ...
Antiemetic
"Journal of Research in Pharmacy Practice. 5 (1): 16-21. doi:10.4103/2279-042X.176556. ISSN 2319-9644. PMC 4776542. PMID ... "Drugs During Pregnancy and Lactation: Handbook of Prescription Drugs and Comparative Risk Assessment. Gulf Professional ... "Review of Cannabinoids and their Antiemetic Effectiveness". Drugs. 25 (1): 52-62. doi:10.2165/00003495-198300251-00006. ISSN ...
Middle Ages
Reports of the Research Committee of the Society of Antiquaries of London. London: Thames and Hudson. ISBN 0-500-99027-1. .. ... Medieval Worlds, Official Website Comparative and interdisciplinary articles about the period.. *Medieval History Database ( ... which increased the effectiveness of cavalry as shock troops. A technological advance that had implications beyond the military ... although they are not supported by historical research.[338] ...
Christianization
The effectiveness of these laws empire-wide is debatable. Christianization of the central Balkans is documented at the end of ... Data From Ann Arbor, Michigan: Inter-university Consortium for Political and Social Research (ICPS). ... "Power and Conversion: A Comparative Study of Christianization in Scandinavia" (PDF), Occasional Papers in Archaeology, 34 ... 22, 6, Viking Society for Northern Research, University College London, 1989, p. 370. ...
Comparative Effectiveness Research | PARTNERS | Arthritis Foundation
... youll have the power to influence the arthritis research conducted and supported by PARTNERS. Learn more about how you can get ... Join PARTNERS: You Have a Role in Research. You will have the power to influence the research conducted and supported by ... Provide ideas for research topics -- to help us decide which research studies to support. ... Its OK if you dont know anything about research. We need people from diverse communities. No matter what work you do, your ...
Comparative effectiveness research across two spine registries | SpringerLink
Background Comparative effectiveness research in spine surgery is still a rarity. In this study, pain alleviation and quality ... Comparative effectiveness research in spine surgery is still a rarity. In this study, pain alleviation and quality of life (QoL ... Comparative effectiveness Spine registry SWISSspine Total disc arthroplasty Benchmark Abbreviations. ALIF. Anterior lumbar ... We are indebted to the SWISSspine and Spine Tango registry groups who made this research possible by populating the database ...
Rethinking comparative effectiveness research - Mayo Clinic
An IBD specialist says investigators must become more creative in their approach to comparative effectiveness research. ... IBD effectiveness trials are needed to foster evidence-based changes in clinical practice, but remain challenging to fund and ... Ideally, comparative effectiveness research (CER) also identifies the features that predict which intervention would be most ... This type of research is intended to foster evidence-based changes in practice that reduce costs and improve patient care. ...
PubMed, HSRProj, and ClinicalTrials.gov Search Strategies for Informing Comparative Effectiveness Research
The Comparative Effectiveness Research as Topic search strategy has been designed to retrieve citations "about" CER. ... PubMed, HSRProj, and ClinicalTrials.gov Search Strategies for Informing Comparative Effectiveness Research. Return to CER ... Comparative Effectiveness Research as Topic, HSRProj CER Search, ClinicalTrials.gov CER Search, ... effective OR effectiveness) AND (comparative OR compared OR "costs and cost analysis" OR "cost-benefit analysis" OR "evidence- ...
Outcomes research and comparative effectiveness | RTI
... involve comparisons of relative treatment costs in addition to relative treatment efficacy.Comparative effectiveness research ( ... Part of the mission of Health Outcomes Research in Medicine is to present evidence from outcomes research to help with ... Stull, D. (2012). Outcomes research and comparative effectiveness. Health Outcomes Research in Medicine, 3(2), e55-e56. https ... Comparative effectiveness research (CER) has increasingly been a focal point of health technology assessments. As defined by ...
Comparative Effectiveness Research Guidelines
Comparative Effectiveness Research - Collaborative Initiative (CER-CI). Advancing Appropriate Use of Comparative Evidence to ... for advancing appropriate use of outcomes research including comparative effectiveness research (CER) to improve patient health ... AMCP, ISPOR and NPC have joined forces to establish the Comparative Effectiveness Research Collaborative Initiative (CER-CI) ... including comparative effectiveness research [CER]) in a wide variability of payer coverage and formulary decisions. ...
Comparative Effectiveness Research | American Journal of Neuroradiology
comparative effectiveness research. PCORI. Patient-Centered Outcomes Research Institute. PCORTF. Patient-Centered Outcomes ... Comparative Effectiveness Research. J.A. Hirsch, P.W. Schaefer, J.M. Romero, J.D. Rabinov, P.C. Sanelli and L. Manchikanti ... An understanding of comparative effectiveness research as a core topic is important for neuroradiologists. It can be used in a ... Comparative effectiveness research: the view from the NHLBI. J Am Coll Cardiol 2009;53:1084-86. ...
U.S. GAO - Comparative Effectiveness: Initial Assessment of the Patient-Centered Outcomes Research Institute
... has established priorities and processes for funding comparative clinical effectiveness research (CER)-which is research that ... evaluates and compares health outcomes and the clinical effectiveness, risks, and benefits of two or more medical treatments, ... has established priorities and processes for funding comparative clinical effectiveness research (CER)-which is research that ... Comparative Effectiveness:. Initial Assessment of the Patient-Centered Outcomes Research Institute. GAO-15-301: Published: Mar ...
Comparative Clinical Effectiveness Research Wants Better Patient and Clinician Involvement
... clinicians and others in the health care community while developing comparative clinical effectiveness research studies will ... Comparative Clinical Effectiveness Research Wants Better Patient and Clinician Involvement. by Nancy Needhima on April 22, 2012 ... clinicians and others in the health care community while developing comparative clinical effectiveness research studies will ... Protection and Affordable Care Act of 2010 created PCORI to fund and promote comparative clinical effectiveness research (CER) ...
Bandit solutions provide unified ethical models for randomized clinical trials and comparative effectiveness research | PNAS
2007) Research on the Comparative Effectiveness of Medical Treatments: Issues and Options for an Expanded Federal Role ( ... We return to CTLS below in the context of comparative effectiveness research, for which it is a interesting model. ... How should the economic cost of treatment enter the equation? There is little dispute that comparative effectiveness research ... Bandit solutions provide unified ethical models for randomized clinical trials and comparative effectiveness research. William ...
Major Depression Comparative Effectiveness Study - Expanding DARTNet -- National Research Network Studies
Read a description of Major Depression Comparative Effectiveness study and view aims, objectives, timeline, status, and contact ... Comparative Effectiveness of Treatment for Major Depression-Utilize commercially available national claims data to evaluate the ... Home / Patient Care / NRN Studies / Major Depression Comparative Effectiveness Study - Expanding DARTNet ... Comparative Safety Study of Antidepressants-Measure rates of adverse effects to include the most common medical side effects ...
U.S. GAO - Comparative Effectiveness Research: Activities Funded by the Patient-Centered Outcomes Research Trust Fund
This research can help patients, doctors, and others make decisions to improve health care. ... The Patient Protection and Affordable Care Act established a fund to support research comparing the effectiveness of available ... Comparative Effectiveness Research:. Activities Funded by the Patient-Centered Outcomes Research Trust Fund. GAO-18-311: ... nonprofit corporation established to carry out and improve comparative clinical effectiveness research (CER), which evaluates ...
comparative effectiveness research | Keywords | The EQUATOR Network
Using Medicare Data for Comparative Effectiveness Research: Opportunities and Challenges
... Vicki Fung, PhD; Richard J. Brand, ... Create specific Medicare data sets for top comparative effectiveness priority topics identified by the Institute of Medicine.32 ... RESEARCH DESIGN AND ANALYTIC STRATEGIES. A substantial body of literature describes the limitations of using observational data ... This lag hinders the ability to compare newer therapies, for which effectiveness and safety information could have the most ...
AHCJ | About-News: Comparative Effectiveness Research Fellows named for 2017
"Its especially important for comparative effectiveness research because this research is meant primarily to serve patients and ... Comparative Effectiveness Research Fellows named for 2017 Date: 08/28/17. COLUMBIA, MO. - Ten journalists have been chosen for ... Specifically, it funds comparative clinical effectiveness research, or CER, as well as supports work that will improve the ... the third class of the AHCJ Fellowship on Comparative Effectiveness Research. The fellowship program was created with support ...
Comparative Clinical Effectiveness Research: Good News In Shades Of Gray | Science-Based Medicine
Comparative Clinical Effectiveness, Comparative Clinical Effectiveness Research, Comparative Effectiveness, Concerns, ... Although comparative clinical effectiveness research is distinct from comparative cost effectiveness research - it is likely ... Comparative Clinical Effectiveness Research: Good News In Shades Of Gray. Val Jones on February 19, 2009 ... What Is Comparative Clinical Effectiveness Research?. The new economic stimulus bill, also known as The American Recovery and ...
Comparative effectiveness research - Wikipedia
"Welcome to the Journal of Comparative Effectiveness Research". Journal of Comparative Effectiveness Research. 1 (1): 1-3. doi: ... "Querying stakeholders to inform comparative effectiveness research". Journal of Comparative Effectiveness Research. 6 (3): 265- ... The Patient-Centered Outcomes Research Institute (PCORI) was established to conduct comparative effectiveness research but the ... Comparative effectiveness research adopts many of the same approaches and methodologies as cost-effectiveness analysis, ...
Comparative Effectiveness Research
Archives for Comparative Effectiveness Research. Geisinger Program Slows Spending Growth on Biologics. A comparative ... "Comparative effectiveness research, to me, is very critical when you have options, and when youre considering the […] more ... Three articles in the Journal of Comparative Effectiveness Research focus on the work and recommendations of a CER-centric ... Clifford Goodman, senior vice president and director at the Center for Comparative Effectiveness Research at the Lewin Group, ...
Comparative Effectiveness Research
You are here: Home / Archives for Comparative Effectiveness Research. ICER Set to Review Canakinumab for Atherosclerosis. The ... "Comparative effectiveness research, to me, is very critical when you have options, and when youre considering the […] more ... Although comparative effectiveness research (CER) is still a relatively recent scientific discipline, its rapid expansion has ... Three articles in the Journal of Comparative Effectiveness Research focus on the work and recommendations of a CER-centric ...
Statistical Methods for Comparative Effectiveness Research of Medical Devices
... Doctoral dissertation, Harvard University, ... Medical devices bring a unique set of challenges for comparative effectiveness research. In this dissertation, I develop ... A recent focus in health care policy is on comparative effectiveness of treatments--from drugs to behavioral interventions to ... statistical methods for comparative effectiveness estimation and illustrate the methodology in the context of three different ...
Comparative Effectiveness Research in Health Services | Springer for Research & Development
The second volume in the Health Services Research series provides a series of perspectives on comparative effectiveness ... research. Motivated by concern from the general public, governments in virtually ... Comparative Effectiveness Research presents a series of chapters of relevance including introductions to areas that are being ... Implementation Science and Comparative Effectiveness Research Ann C. Bonham, Mildred Z. Solomon, Brian Mittman, Alexander K. ...
Are We Mature Enough to Make Use of Comparative Effectiveness Research? - The Health Care Blog
So, is it worth wasting our time and money on comparative effectiveness research? Im hoping that this is a new day - the ... Are We Mature Enough to Make Use of Comparative Effectiveness Research?. Feb 27, 2009. • 39 ... What other way can one force physicians and hospitals to pay attention to comparative effectiveness research? As I commented to ... What other way can one force physicians and hospitals to pay attention to comparative effectiveness research? As I commented to ...
Journal of Comparative Effectiveness Research - Wikipedia
The journal covers all aspects of comparative effectiveness research, including patient-centered outcomes research, ... The Journal of Comparative Effectiveness Research is a peer-reviewed medical journal that was established in 2012 and is ... "Journal of Comparative Effectiveness Research". 2016 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. ... The editors-in-chief are Sheldon Greenfield (University of California, Irvine) and Eugene Rich (Mathematica Policy Research). ...
Comparative Effectiveness Research (CER) | Clinical & Translational Science Institute
New UCSF Initiative to Improve Access to and Analysis of Large Health Data Sets for Comparative Effectiveness Research August ... Accelerating Research to Improve Health. The UCSF Clinical and Translational Science Institute (CTSI) is part of the Clinical ... CTSI is providing services and resources to support Patient-Centered Outcomes Research Institute grants. ... CTSI Involved in Three Awards to Shape National Clinical Research Data Network ...
Do-not-resuscitate status and observational comparative effectiveness research in patients with septic shock*
... Crit Care Med. ... assess the importance of including do-not-resuscitate status in critical care observational comparative effectiveness research ... of early do-not-resuscitate status into more administrative databases may improve observational comparative effectiveness ... 2Center for Quality of Care Research, Baystate Medical Center, Springfield, MA. 3Division of General Internal Medicine, ...
Dr. Wes: Our New Era of Comparative Effectiveness Research
Trendspotter: Comparative Effectiveness Research to Cut Costs Without Rationing
After a prolonged debate over government-sponsored comparative effectiveness research, Congress decided to authorize it in the ... After a prolonged debate over government-sponsored comparative effectiveness research, Congress decided to authorize it in the ... Trendspotter: Comparative Effectiveness Research to Cut Costs Without Rationing. @media screen and (max-width: 468px) { .video- ...
Peer-led and Telehealth Comparative Effectiveness Research (CER) Adoption for Diabetes Prevention and Management - Full Text...
Peer-led and Telehealth Comparative Effectiveness Research (CER) Adoption for Diabetes Prevention and Management. The safety ... innovative interventions to increase adoption of findings from comparative effectiveness research (CER) for diabetes management ... To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For ... To learn more about this study, you or your doctor may contact the study research staff using the contact information provided ...
RFA-OD-10-011: Recovery Act Limited Competition: Institutional Comparative Effectiveness Research Mentored Career Development...
Institutional Comparative Effectiveness Research Mentored Career Development Award (KM1) RFA-OD-10-011. NIH ... 4) Feasibility of research topic (including time necessary for research).. The Comparative Effectiveness Research-Coordination ... "Comparative effectiveness research is the conduct and synthesis of research comparing the benefits and harms of different ... research-intensive institutions to support mentored career development in support of comparative effectiveness research (CER) ...
Private, voluntary or public? Comparative cost-effectiveness in community mental health care - LSE Research Online
Private, voluntary or public? Comparative cost-effectiveness in community mental health care ... Comparative cost-effectiveness in community mental health care. Policy and Politics, 27 (1). pp. 25-42. ISSN 0305-5736 ... Personal Social Services Research Unit. Subjects:. R Medicine , RZ Other systems of medicine. B Philosophy. Psychology. ... Mission Statement & FAQs , Contact us , Takedown Policy , LSE Experts , LSE Research Online supports OAI 2.0 with a base URL of ...
PCORIOutcomes researchTreatmentsInterventionsObservationalCommittee on Comparative Effectiveness Research PrioritizationTrialsJournal of Comparative Effectiveness ResearchCost effectiveness2016TherapiesPopulationsEfficacyDisseminationPrioritizationFederal Coordinating CouncilApproachesPriorities for Comparative Effectiveness ResearchStudiesCliniciansConduct comparative effectivenessMethodologyInvestment in comparative effectiveness researchStudyFindingsComparesPatientsPracticesPolicymakersDataInformTreatmentSafety of antidepressantsResearchersMethods in comparative effectiveness researchGoal of comparative effectiveness researchAssessPracticeDecisionsDARTNetChallengesInstituteInstitutesOverseeAdoptionCaliforniaSearchEpidemiologic and health servicesStrategiesConstraintSubsetMedicalCare
PCORI35
- PCORI will ensure that its research is not construed as mandates for practice guidelines or coverage recommendations. (nursingworld.org)
- PCORI is developing a research agenda and plan for commissioning PCOR. (nursingworld.org)
- The Patient-Centered Outcomes Research Institute (PCORI) was established to conduct comparative effectiveness research but the Patient Protection and Affordable Care Act (PPACA) prohibits it from using cost per QALY ICER thresholding. (wikipedia.org)
- The Patient-Centered Outcomes Research Institute (PCORI) has established priorities and processes for funding comparative clinical effectiveness research (CER)-which is research that evaluates and compares health outcomes and the clinical effectiveness, risks, and benefits of two or more medical treatments, services, or items such as health care interventions-and is developing dissemination plans, consistent with the legislative requirements of the Patient Protection and Affordable Care Act (PPACA). (gao.gov)
- PCORI also developed a research agenda to identify how each priority would be addressed. (gao.gov)
- PCORI has established a multi-step research funding process designed to assess and select contract applications for funding. (gao.gov)
- Per legislative requirement, PCORI is developing a peer review assessment process to review final reports submitted by contract awardees and is in the process of developing a plan for the dissemination of funded research potentially beginning in 2015, in coordination with the Agency for Healthcare Research and Quality. (gao.gov)
- PCORI has started awarding contracts for research and plans to award additional contracts through 2019. (gao.gov)
- As of October 2014, PCORI has awarded 360 contracts to fund research projects, committing a total of $670.8 million to them. (gao.gov)
- PCORI expects to commit about $2.6 billion to research contracts, out of $3.5 billion in total estimated spending. (gao.gov)
- PCORI has developed initial plans for evaluating the institute's efforts against its three strategic goals, which are to increase information, speed implementation, and influence research. (gao.gov)
- In its strategic plan, PCORI notes that these are meant to be long-term measures because research typically requires several years to complete and additional years for the results to be disseminated and implemented. (gao.gov)
- PCORI, which began operation in 2010, is required to identify research priorities, establish a research project agenda, fund research consistent with its research agenda, and disseminate research results, among other things. (gao.gov)
- To fund PCORI, PPACA established the Patient-Centered Outcomes Research Trust Fund, through which the institute is expected to receive an estimated $3.5 billion from fiscal years 2010 through 2019. (gao.gov)
- Anne C. Beal, M.D., M.P.H., of the Patient-Centered Outcomes Research Institute (PCORI), Washington, D.C., presented the article at a JAMA media briefing at the National Press Club. (medindia.net)
- The PCORI mission statement commits to producing and promoting high-integrity research that is 'guided by patients, caregivers, and the broader healthcare community. (medindia.net)
- The founding legislation required PCORI to develop national priorities for research and a research agenda, and to post both for a 45- to 60-day public comment period before major funding for research could begin. (medindia.net)
- The Patient-Centered Outcomes Research Institute (PCORI) made about $2 billion in commitments for awards in fiscal years 2010 through 2017. (gao.gov)
- PCORI is a federally funded, nonprofit corporation established to carry out and improve comparative clinical effectiveness research (CER), which evaluates and compares the health outcomes and the clinical effectiveness, risks, and benefits of two or more medical treatments, services, or items. (gao.gov)
- PCORI provides funding through award commitments from the Patient Centered Outcomes Research Trust Fund (Trust Fund) and may pay these awards over multiple years. (gao.gov)
- Of the $2 billion PCORI committed as of the end of fiscal year 2017, about $1.6 billion (or 79 percent of its commitments) is for research awards, and $325 million (or 16 percent) is for building the capacity to use existing health data for research. (gao.gov)
- Through fiscal year 2017, commitments for dissemination and implementation awards-intended to share CER findings with potential users of this research-were limited because most PCORI-funded research was still underway. (gao.gov)
- As most PCORI-funded CER had not yet been completed due to the time needed to conduct this research, HHS efforts focused instead on the dissemination and implementation of CER funded by other federal entities. (gao.gov)
- CTSI featured in Nature news blog announcing PCORI research grants. (ucsf.edu)
- Earlier this fall, PCORI (the Patient Centered Outcomes Research Institute) released a request for funding applications for comparative effectiveness studies of Multiple sclerosis (MS) disease modifying therapies (DMTs). (mscenter.org)
- WASHINGTON, DC - The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved the development of two new PCORI Funding Announcements (PFAs) that together will offer up to $41 million in support of comparative clinical effectiveness research (CER). (pcori.org)
- Pregnancy may motivate women to seek treatment, and PCORI wants to fund research that addresses some of the many barriers to care that they face. (pcori.org)
- The Patient-Centered Outcomes Research Institute (PCORI) represents an effort by the US government to address this shortcoming by funding comparative effectiveness research (CER). (npcnow.org)
- these priorities will set the tone for all of the institute's future activities.The research also highlights the difficult questions PCORI will face as the public dialogue on its national research priorities and research agenda begins. (npcnow.org)
- Last week the U.S. Government Accountability Office (GAO) appointed several new members to the board of the Patient-Centered Outcomes Research Institute (PCORI). (medicallessons.net)
- PCORI, comparative effectiveness and the ACA: improving patient outcomes or cookbook medicine? (freethesaurus.com)
- PCORI committed $68 million in April to develop the national data network through the creation or expansion of up to eight health system-based Clinical Data Research Networks and up to 18 Patient-Powered Research Networks organized by groups of patients interested in participating in clinical research. (healthcareitnews.com)
- The Affordable Care Act established the Patient-Centered Outcomes Research Institute (PCORI), a private nonprofit entity, to oversee such research. (hhs.gov)
- The Affordable Care Act created a non-profit Patient-Centered Outcomes Research Institute (PCORI) to conduct research that compares the clinical effectiveness of medical treatments. (philips.com)
- The panel included representatives of the American Diabetes Association and the American Heart Association as well as experts from industry, academic and government research institutes, and the Patient-Centered Outcomes Research Institute (PCORI). (biomedcentral.com)
Outcomes research32
- Similar to CER, patient-centered outcomes research (PCOR) is designed to inform health care decisions by providing evidence on the effectiveness, benefits and harms of different treatment options for different patients. (nursingworld.org)
- Two organizations focused on CER and PCOR are the Agency for Healthcare Research and Quality and the Patient Centered Outcomes Research Institute. (nursingworld.org)
- Patient-centered outcomes research" (PCOR) is the type of research that will be the focus of PCORI's work. (nursingworld.org)
- She conducts research ranging from randomized controlled trials to systematic reviews focusing on quality of care, evidence-based practice among clinicians and outcomes research in healthcare delivery systems. (nursingworld.org)
- Health Outcomes Research in Medicine , 3 (2), e55-e56. (rti.org)
- Part of the mission of Health Outcomes Research in Medicine is to present evidence from outcomes research to help with decisions about which treatments to pursue and the efficacy of those treatments. (rti.org)
- AMCP, ISPOR and NPC have joined forces to establish the Comparative Effectiveness Research Collaborative Initiative (CER-CI) for advancing appropriate use of outcomes research including comparative effectiveness research (CER) to improve patient health outcomes. (ispor.org)
- Since there are a limited number of accepted principles for the interpretation of non-experimental design outcomes research studies for drug formulary and health care decisions, a consensus-based set of principles, combined with educational training and tools, would promote the development, application, and interpretation of appropriate evidence for health care technology and enhance the formulary decision-making process. (ispor.org)
- The goal of the CER Collaborative Initiative is to provide greater uniformity and transparency in the use and evaluation of outcomes research information including observational studies for coverage and health care decision making by providing a user-friendly toolkit to help decision makers navigate through the various types of observational study methods used to generate outcomes research information for evidence-based health care decision making. (ispor.org)
- The goal of Part 1 is to develop a compendium of papers on"Interpreting Outcomes Research Studies for Health Care Decisions" for four outcomes research study types: a) prospective observational studies, b) retrospective observational database studies, c) modeling studies and d) indirect treatment comparison studies. (ispor.org)
- The goal of Part 2 is to identify a framework to assess evidence across multiple outcomes research study methods (body of evidence) including experimental design studies [randomized clinical trial studies - RCTs] and observational studies. (ispor.org)
- The PPACA states: The Patient-Centered Outcomes Research Institute. (wikipedia.org)
- and (5) accelerating patient-centered outcomes research and methodological research. (gao.gov)
- Added participation by patients, clinicians and others in the health care community while developing comparative clinical effectiveness research studies will make such studies far more constructive in clinical decision-making, states the Patient-Centered Outcomes Research Institute, in an article published in the April 18 issue of JAMA , a theme issue on comparative effectiveness research. (medindia.net)
- The institute developed a definition of patient-centered outcomes research that emphasizes the voice of the patient in assessing health care options. (medindia.net)
- However, as health outcomes research enabled by electronic medical records becomes common ( 6 ), comparative effectiveness research (CER), which is logically, if not by name, a kind of clinical trial ( 7 ), will extend the duration of ethical questions, and the number of patients affected by such questions, almost without bound. (pnas.org)
- The journal covers all aspects of comparative effectiveness research, including patient-centered outcomes research, pharmacoeconomics and health economics, relating to diagnostics, therapeutics, surgical procedures, or other healthcare services or options. (wikipedia.org)
- We found that the Patient-Centered Outcomes Research Institute and Department of Health and Human Services expect to receive about $4 billion from the fund by the end of fiscal year 2019. (gao.gov)
- Gruman: Tell me how your organization views the relationship between CER and patient-centered outcomes research (PCOR). (cfah.org)
- The fellowship program was created with support from the Patient-Centered Outcomes Research Institute to help reporters and editors produce more accurate in-depth stories on medical research and how medical decisions are made. (healthjournalism.org)
- The Patient-Centered Outcomes Research Institute , an independent nonprofit, nongovernmental organization located in Washington, D.C., was authorized by Congress in 2010 to improve the quality and relevance of evidence available to help patients, caregivers, clinicians, employers, insurers and policymakers make informed health decisions. (healthjournalism.org)
- A comparative study of new biologic and small-molecule treatments for inflammatory bowel disease is slated to receive $2.4 million in grant funding from the Patient-Centered Outcomes Research Institute and the Crohn's and Colitis Foundation (CCF). (healtheconomics.com)
- CTSI is providing services and resources to support Patient-Centered Outcomes Research Institute grants. (ucsf.edu)
- To get a better understanding of comparative effectiveness research and its relationship with oncology services, The ASCO Post recently spoke with Gary Lyman, MD, Professor of Medicine at Duke University and the Duke Cancer Institute, where he is Director of the Comparative Effectiveness and Outcomes Research Program. (ascopost.com)
- The Center for Health Services and Outcomes Research is delighted to share its experience in Comparative Effectiveness Research. (jhsph.edu)
- The SVI (stent versus indomethacin) trial (NCT024762279) by the US cooperative for Outcomes Research in Endoscopy (USCORE) group is an ongoing non-inferiority trial that compares indomethacin alone to the combination of indomethacin and PDS in 1430 high risk patients with the primary outcome of pancreatitis. (centerwatch.com)
- Methods: The Task Force was commissioned and a Chair was selected by the International Society for Pharmacoeconomics and Outcomes Research Board of Directors in October 2007. (ispor.org)
- The Patient-Centered Outcomes Research Institute Board of Governors selected a consortium led by the Harvard Pilgrim Health Care Institute to serve as the coordinating center for a new national data network designed to enhance the nation's ability to conduct patient-centered comparative effectiveness research. (healthcareitnews.com)
- In response to the need for data to support comparative effectiveness research (CER), or patient-centered outcomes research, the Agency for Healthcare Research and Quality (AHRQ) and CDC's National Program of Cancer Registries (NPCR) developed a special data collection enhancement project to help answer specific CER questions through the development of analytic datasets. (cdc.gov)
- CER also uses systematic reviews, evidence-quality appraisal, and health outcomes research to provide a methodologic framework for assessing biologic patient subgroups. (blogspot.com)
- Value in Health (ISSN 1098-3015) publishes papers, concepts, and ideas that advance the field of pharmacoeconomics and outcomes research as well as policy papers to help health care leaders make evidence-based decisions. (ispor.org)
- International Society for Pharmacoeconomics and Outcomes Research (ISPOR) is a nonprofit, international, educational and scientific organization that strives to increase the efficiency, effectiveness, and fairness of health care resource use to improve health. (ispor.org)
Treatments25
- NEW YORK (GenomeWeb News) - When President Barack Obama included over $1 billion in the federal stimulus spending bill in February to study which healthcare treatments are most beneficial for most patients and most cost-effective, he signaled that comparative effectiveness research likely will be part of his administration's effort to change the healthcare system. (genomeweb.com)
- 1 , 2 Dr Lind's historic controlled study of 6 different treatments for scurvy was, in reality, the first true "evidence" of comparative effectiveness research (CER). (ajnr.org)
- Dr. Ted Feldman, NorthShore University HealthSystem, Evanston IL, explains the challenges involved in comparing the effectiveness of treatments. (scai.org)
- Although randomized clinical trials are the gold standard for establishing the effectiveness of medical treatments, it is widely recognized that they raise nontrivial ethical issues. (pnas.org)
- The Patient Protection and Affordable Care Act established a fund to support research comparing the effectiveness of available treatments. (gao.gov)
- This study examines the key features of government agencies created in Australia, France, Germany, and the United Kingdom to lead research into the comparative effectiveness of medical treatments, procedures, and technologies. (commonwealthfund.org)
- A part of the recent discussions about U.S. health system reform has focused on the need for better evidence on the comparative effectiveness of various clinical treatments. (commonwealthfund.org)
- Just knowing more about the comparative effectiveness of symptomatic treatments would help. (cfah.org)
- The Institute for Clinical and Economic Review (ICER) on Friday released a Draft Evidence Report assessing the comparative clinical effectiveness and value of treatments for moderate-to-severe plaque psoriasis. (healtheconomics.com)
- The Institute for Clinical and Economic Review (ICER) says upcoming reports will focus on the comparative clinical effectiveness and value of high-risk prostate cancer and hereditary amyloidosis treatments. (healtheconomics.com)
- A recent focus in health care policy is on comparative effectiveness of treatments--from drugs to behavioral interventions to medical devices. (harvard.edu)
- Comparative Effectiveness Research presents a series of chapters of relevance including introductions to areas that are being incorporated when comparing treatments, country-specific applications, patient-centred approaches, and modern methods. (springer.com)
- A new clinical review by experts at The University of Nottingham says there is very little research evidence to show which treatments work best and whether expensive treatments are any better than traditional ones. (healthcanal.com)
- What is needed is a whole rethink about acne research into which treatments should be started first, how well do commonly used treatment compare against each other, which treatments should be used for maintaining control and which combinations are best. (healthcanal.com)
- By establishing legal incentives for evidence-based medicine, safe harbors founded on comparative effectiveness research results also would reduce the need for defensive medicine and its unnecessary, costly treatments. (freethesaurus.com)
- The Institute of Medicine identified 25 of the most urgently needed areas for research of which three pertain to Urology: screening for prostate cancer, comparing effectiveness of treatments for localized prostate cancer, and use of imaging in diagnosing, staging, and monitoring cancer patients. (elsevier.com)
- Insufficient evidence regarding the effectiveness of medical treatments has been identified as a key source of inefficiency in the U.S. healthcare system. (hhs.gov)
- Unlike randomized controlled trials (RCTs), which examine the efficacy of tests, treatments, or quality improvement strategies in highly specified samples, CER addresses their effectiveness in a broader and more diverse set of populations and settings. (hhs.gov)
- Objective To investigate the comparative effectiveness of all treatments for patellofemoral pain (PFP). (bmj.com)
- The ongoing work of the Depression Clinical and Research Program (DCRP) at Massachusetts General Hospital is helping to define depression treatments for the field. (massgeneral.org)
- The DCRP conducts leading-edge research in the area of depression, with a focus on testing novel antidepressant treatments and developing new tools to understand the biological changes that occur in this condition. (massgeneral.org)
- In 2015, the Alzheimer's Drug Discovery Foundation convened an advisory panel on "The Prevention of Dementia and Mild Cognitive Impairment as Variables to Consider In the Comparative Effectiveness of Treatments for Common Chronic Conditions. (biomedcentral.com)
- The Obama administration has made a major investment in comparative effectiveness research (CER) to learn what treatments work best for which patients. (dukeupress.edu)
- Boston, MA, USA - Health care companies face increased pressure to compare the effectiveness of new treatments as early as possible. (ispor.org)
- While randomized head-to-head trials are the gold standard for comparing treatments, the new approach can provide indirect comparative evidence when such trials are not available. (ispor.org)
Interventions16
- One alternative that avoids some of the challenges of head-to-head prospective trials is network meta-analysis, which allows investigators to make inferences about the effectiveness of interventions that have not been directly compared with one another. (mayoclinic.org)
- Comparative effectiveness research (CER) is the direct comparison of existing health care interventions to determine which work best for which patients and which pose the greatest benefits and harms. (wikipedia.org)
- The Institute for Clinical and Economic Review provides independent evaluation of the clinical effectiveness and comparative value of health care interventions, while also overseeing the New England Comparative Effectiveness Public Advisory Council (CEPAC), an independent body of physicians and patient representatives that aids patients, physicians and policymakers in the application and use of comparative effectiveness information to improve the quality and value of healthcare in the region. (wikipedia.org)
- The initial portfolio of funded research is expected to cover a range of conditions and interventions, to be exemplary of stakeholder-engaged research, and to be highly aligned with the criteria. (medindia.net)
- Our work will include comparative effectiveness research, with an emphasis on causal inference methods for complex longitudinal data from both observational studies and randomized trials, e.g. to assess effects of interventions on cardiovascular disease, cancer, and others. (ki.se)
- The overall objective of this protocol is to implement evidence-informed, innovative interventions to increase adoption of findings from comparative effectiveness research (CER) for diabetes management and prevention in South Florida older veterans. (clinicaltrials.gov)
- The low prevalence of CE research exists across CE studies with a broad array of interventions and characteristics. (harvard.edu)
- Comparative effectiveness research (CER) involves comparing the benefits and harms of interventions for clinical conditions, which will assist patients, providers, and policy makers in formulating informed decisions that will improve health care [ 1 ]. (plos.org)
- To further evaluate effectiveness and assess less common or delayed toxicities in the broad cancer population, additional sources of evidence are needed to guide the evaluation and approval of new interventions and better guide clinical decisions in the oncology setting. (ascopost.com)
- Although we don't specifically link cost savings to comparative effectiveness research, identifying interventions that provide the most value to patients is fundamental, and any cost benefits may certainly be a desired outcome. (ascopost.com)
- The Institute of Medicine Committee on Comparative Effectiveness Research Prioritization was charged with developing a portfolio of priority topics that reflected balance across research areas, populations, type of interventions, and methodologies. (nap.edu)
- Comparative Effectiveness of Two Tobacco Cessation Interventions for Employees of Partners HealthCare Inc. (centerwatch.com)
- Lahey Hospital & Medical Center launched the Comparative Effectiveness Research Institute (CERI) to better assess quality and effectiveness of medical care interventions. (lahey.org)
- Comparative effectiveness research is the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat, and monitor health conditions in "real world" settings. (nih.gov)
- Five groups (A-E) will be evaluated to determine the effectiveness of three interventions. (biomedcentral.com)
- 2 Similarly, research funders and researchers are increasingly focused on translating new interventions and technologies from the laboratory to clinical practice and then healthcare policy in order to establish and implement new standards of high quality care and improve patient outcomes. (bmj.com)
Observational11
- As membership-based organizations representing the leadership in managed care pharmacy, the research community and the pharmaceutical industry, AMCP, ISPOR and NPC are uniquely positioned to collaborate in advancing understanding, interpretation and appropriate use of observational studies results (including comparative effectiveness research [CER]) in a wide variability of payer coverage and formulary decisions. (ispor.org)
- Traditional observational comparative effectiveness research is conducted using large data sets, such as claims databases. (nih.gov)
- The target trail framework provides a conceptual framework and causal analytical methods that allows us to address such research questions and emulate a hypothetical experiment by using observational data. (ki.se)
- To assess the importance of including do-not-resuscitate status in critical care observational comparative effectiveness research. (nih.gov)
- Among patients with septic shock, do-not-resuscitate status acts as a strong confounder that may inform past discrepancies between observational and randomized studies of activated protein C. Inclusion of early do-not-resuscitate status into more administrative databases may improve observational comparative effectiveness methodology. (nih.gov)
- Methods: We conducted an observational study of clinical trials addressing priority research topics defined by the Institute of Medicine and conducted in the US between 2007 and 2010. (harvard.edu)
- DARTNet can be used for observational comparative effectiveness research, which may provide important information about safe and effective health care. (annals.org)
- The Distributed Ambulatory Research in Therapeutics Network (DARTNet) is a federated network of electronic health data that was created to facilitate advanced observational comparative effectiveness research and examine outcomes associated with prescription medications and devices. (annals.org)
- Comparative effectiveness of any particular treatment can be established by interventional clinical trials, observational real-world evidence studies, or systematic review and meta-analysis. (linguamatics.com)
- Finally, it also used state-of-the-art statistical and econometric comparative effectiveness methods to mimic the effect of random assignment and control for sources of confounding inherent in large observational studies. (doaj.org)
- Fourth, CER uses observational or pragmatic research methods designed to enhance generalizability, including treatment allocation and the measurement of outcomes in real-world settings that are relevant to patients. (hhs.gov)
Committee on Comparative Effectiveness Research Prioritization2
- The Committee on Comparative Effectiveness Research Prioritization released 100 topics that it says should be the focus of research. (managedcaremag.com)
- Committee on Comparative Effectiveness Research Prioritization. (freethesaurus.com)
Trials19
- Effectiveness trials, on the other hand, assess how well a particular intervention works compared with other options commonly used in clinical practice. (mayoclinic.org)
- Effectiveness trials require substantially larger patient populations than placebo-controlled trials, which makes them far more costly and harder to recruit. (mayoclinic.org)
- CER may be a systematic research review evaluating existing clinical trials, clinical studies, and other research. (nursingworld.org)
- These clinical research trials measure the benefit produced by the treatment in routine clinical practice. (wikipedia.org)
- Although they seek to demonstrate an intervention's effectiveness at a high level of statistical significance, randomized trials will always assign some patients to an inferior treatment and they will often assign patients to a treatment for which there is already partial evidence of its inferiority. (pnas.org)
- The RE-ADAPT (REsearch in ADAptive methods for Pragmatic Trials) project was supported by the NHLBI (award 1RC4HL106363-01). (annals.org)
- Others will point to the government's new paradigm for requiring significant industry sponsorship to fund their comparative effectiveness research (CER) trials as opening the potential for the development of "pay to play" relationships to develop between government and industry. (blogspot.com)
- Clinical trials of cost-effectiveness of different strategies for initial treatment and maintenance therapy of acne are needed. (healthcanal.com)
- The COMET (Core Outcome Measures in Effectiveness Trials) Initiative promotes the development and application of core outcome sets (COS), including relevant studies in an online database. (plos.org)
- The COMET (Core Outcome Measures in Effectiveness Trials) Initiative ( www.comet-initiative.org ) promotes the development and application of COS, by including pertinent individual studies in a publically available online database. (plos.org)
- How does the randomized controlled trials process fit in with comparative effectiveness research? (ascopost.com)
- Randomized controlled clinical trials and meta-analyses of such trials are still the gold standard and backbone of comparative effectiveness research and the most definitive way to assess treatment efficacy. (ascopost.com)
- The goal of comparative effectiveness research is to go beyond the boundaries of randomized trials and gather all the credible evidence on a given clinical question so that clinicians can make more rational choices in treatment selection. (ascopost.com)
- it is a way to make the best use of comparative data, and randomized trials will always be a component in that process. (ascopost.com)
- Eligible studies were randomized clinical trials (RCTs) and comparative cohort studies in adults that included two or more treatment options for GD. (pituitary.org)
- However, much like the practice of medicine as a whole, many of our clinical decisions are not rooted in large comparative effectiveness trials. (asahq.org)
- Despite the increasing uptake of electronic medical record (EMR) software in Primary Care, there has been little effort to date to utilize this software to conduct pragmatic comparative effectiveness research (CER) trials in Primary Care. (thewinnower.com)
- Critically important clinical trials could not be conducted without the commitment of FORCE to the development and completion of cancer prevention, detection, treatment and quality of life research. (facingourrisk.org)
- Prognosis research studies too often fall a long way short of the high standards required in other fields, such as therapeutic trials and genetic epidemiology. (bmj.com)
Journal of Comparative Effectiveness Research3
- Journal of Comparative Effectiveness Research. (wikipedia.org)
- The Journal of Comparative Effectiveness Research is a peer-reviewed medical journal that was established in 2012 and is published by Future Medicine. (wikipedia.org)
- Three articles in the Journal of Comparative Effectiveness Research focus on the work and recommendations of a CER-centric conference convened last year by the PhRMA Foundation and the Academy of Managed Care Pharmacy. (healtheconomics.com)
Cost effectiveness11
- Comparative effectiveness research adopts many of the same approaches and methodologies as cost-effectiveness analysis, including the use of incremental cost-effectiveness ratios (ICERs) and quality-adjusted life years (QALYs). (wikipedia.org)
- Over time, the international agencies have begun to consider cost-effectiveness, as well as clinical effectiveness. (commonwealthfund.org)
- Any mention of "comparative cost effectiveness" or value-based language is notably absent. (sciencebasedmedicine.org)
- Although comparative clinical effectiveness research is distinct from comparative cost effectiveness research - it is likely that payers will use CCER to build their formularies. (sciencebasedmedicine.org)
- Background England's National Institute for Health and Care Excellence (NICE) and the US' Institute for Clinical and Economic Review (ICER) both conduct cost-effectiveness evaluations for new cancer drugs to help payers make drug coverage decisions. (lse.ac.uk)
- Methods We compared the methods and results of publicly available cost-effectiveness evaluations performed by ICER and NICE of similarly assessed cancer drugs. (lse.ac.uk)
- Assessments were compared based on incremental cost-effectiveness ratio, comparator treatment, price, recommendation, and the design of the economic evaluation. (lse.ac.uk)
- Findings Among 11 commonly assessed cancer drugs, ICER and NICE were in concordance for 7 evaluations and in discordance on the cost-effectiveness and coverage decisions for 4 drugs. (lse.ac.uk)
- With the ongoing focus on healthcare outcomes-based payment models, pharmaceutical companies face powerful pressures to demonstrate not just safety and efficacy of a new treatment, but also both cost effectiveness and comparative effectiveness. (linguamatics.com)
- And, "For now, Obama has stopped short of advocating coverage decisions that combine clinical finding with cost effectiveness. (honestmedicine.com)
- We seek to understand the determinants of illness and well-being, and to improve the quality and cost-effectiveness of health care. (kaiserpermanente.org)
20162
- Gorst SL, Gargon E, Clarke M, Smith V, Williamson PR (2016) Choosing Important Health Outcomes for Comparative Effectiveness Research: An Updated Review and Identification of Gaps. (plos.org)
- With Statista you are very public to know powerful parts and strengthen your book comparative effectiveness research in health services 2016 facility. (yanodan.com)
Therapies9
- Information produced by comparative effectiveness research will be hard to use appropriately because context and emotion often dominate a patient's rational decisionmaking and because therapies are provided in different health care environments, making small differences between therapies basically meaningless. (rand.org)
- The Institute for Clinical and Economic Review (ICER) on Tuesday announced plans to develop a review assessing the comparative clinical effectiveness and value of biologic therapies for moderate-to-severe asthma. (healtheconomics.com)
- When applied to the implantation of cardiovascular resynchronization therapies to examine comparative survival, only 3 of 8 studies report arm-specific follow-up. (harvard.edu)
- This lack of well-conducted research to test over-the-counter and prescription therapies is putting patients at risk of ineffective treatment and makes treatment decisions for patients and doctors very difficult. (healthcanal.com)
- Professor Williams and his team are calling for new research into the comparative effectiveness of common topical and systemic therapies and to improve the understanding of the natural history, specific types, and triggers of acne, and how treatment affects the course of this poorly understood disease. (healthcanal.com)
- By helping clinicians, patients, payers, and others to better distinguish between effective and ineffective (or potentially harmful) therapies, comparative effectiveness research (CER) has the potential to slow the growth of spending on healthcare without adversely affecting the quality of care. (hhs.gov)
- The rich intellectual environment at Stanford, paired with our accessibility to the most advanced technology, is unmatched and ensures the rapid translation of pioneering laboratory research into life-saving clinical therapies for our patients. (stanford.edu)
- From anti-cancer therapies and stem cell transplantation therapies for spinal cord injury to the elucidation of retinal neural circuitry and gene-environment interactions in fetal development, our research scientists are making quick progress tackling some of the most complex neurological disease questions in the neurodegenerative and neuroregenerative fields today. (stanford.edu)
- Promising therapies are suggested by and explored with laboratory research, and some of these therapies, such as mild hypothermia, are then tested in the clinic. (stanford.edu)
Populations3
- We report numerical experiments that yield a heuristic approximation that applies even to very large horizons, and we propose a near-optimal strategy that remains valid even when the horizon is unknown or unbounded, thus applicable to comparative effectiveness studies on large populations or to standard-of-care recommendations. (pnas.org)
- The first half of the chapter is a "portfolio analysis," which shows the representation of research areas, study populations, comparators, and study methodologies within the final 100 topics. (nap.edu)
- Second, CER focuses on comparisons of alternative clinical approaches that have demonstrated efficacy in RCTs but may differ with respect to effectiveness in some populations, side effects, or costs. (hhs.gov)
Efficacy5
- and a school based care approach that examines the efficacy of school-based programs to impact asthma outcomes including effectiveness of linkages between schools and the healthcare providers. (biomedcentral.com)
- To understand what CER is and anesthesiology's potential role, it is essential to have a basic understanding of the concepts of efficacy, effectiveness, and efficiency. (asahq.org)
- In this multicenter, randomized, controlled, double-blind, double-dummy clinical trial, in which we will use the comparative effectiveness research method, we will compare the efficacy of two commonly used Chinese patent medicines for angina patients diagnosed with qi deficiency and blood stasis syndrome. (biomedcentral.com)
- For example, this type of research could be used to economically compare the efficacy of pharmaceutical classes with many similar options (known as "me too" drugs). (thewinnower.com)
- The six statin medications currently on the market in Canada are an exemplar for this study as comparative efficacy data, especially on patient-centred outcomes is either non-existent or not publicly available. (thewinnower.com)
Dissemination3
- The Harvard Pilgrim team includes experts in data standards, data security and privacy, medical ethics, patient-reported outcomes, project management, and research communications and dissemination. (healthcareitnews.com)
- Dissemination and Adoption of Comparative Effectiveness Research Findings When Findings Challenge Current Practices. (hhs.gov)
- Recognizing this fact, a sizable portion of the ARRA funding was devoted to research on the dissemination and implementation of CER. (hhs.gov)
Prioritization2
- The development process extended from July to December 2011, and included examination of other recent prioritization efforts and input received through discussions with stakeholder groups, including patients and their caregivers, clinicians, hospitals and health care systems, payers, the life sciences industry, and the research community. (medindia.net)
- The Comparative Effectiveness Research - Coordination and Implementation Team (CER-CIT) will require the use of the Federal Coordinating Council's prioritization criteria for scientifically meritorious research and investments for all projects funded with OS ARRA funds. (nih.gov)
Federal Coordinating Council3
- The government's new CCER initiative will be administered through a Federal Coordinating Council for clinical comparative effectiveness research. (sciencebasedmedicine.org)
- The same criticism applies for the members of the Federal Coordinating Council for Comparative Effectiveness Research that was recently named by HHS. (honestmedicine.com)
- The Federal Coordinating Council for Comparative Effectiveness Research used similar terms to define CER ( Federal Coordinating Council for Comparative Effectiveness Research, 2009 ). (hhs.gov)
Approaches6
- This review article explores the Medicare data available for researchers and approaches that could be used to enhance the data%u2019s value for comparative effectiveness research. (ajmc.com)
- A type of health care research that compares the results of one approach for managing a disease to the results of other approaches. (sciencebasedmedicine.org)
- In addition to traditional health sciences methods, modern approaches to comparative effectiveness research now include greater emphasis on social sciences frameworks such as economics, ethics, and implementation science. (springer.com)
- Country-specific examples include an overview chapter on national approaches from various countries in Europe, Australia, and Canada, as well as specific chapters on comparative effectiveness research in Brazil and in the United States. (springer.com)
- Recognizing the challenges to conducting valid retrospective epidemiologic and health services research studies, a Task Force was formed to develop a guidance document on state of the art approaches to frame research questions and report findings for these studies. (ispor.org)
- Prognosis research findings should thus be integral to clinical decision making, healthcare policy, and discovering and evaluating new approaches to patient management. (bmj.com)
Priorities for Comparative Effectiveness Research1
- I]nnumerable practical decisions facing patients and doctors every day do not rest on a solid foundation of knowledge about what constitutes the best choice of care," says the committee report, Initial National Priorities for Comparative Effectiveness Research. (managedcaremag.com)
Studies23
- Provide ideas for research topics -- to help us decide which research studies to support. (arthritis.org)
- The evidence is generated from research studies that compare drugs, medical devices, tests, surgeries, or ways to deliver health care. (nursingworld.org)
- This CER Systematic Reviews search strategy was developed to identify secondary research such as systematic reviews, meta-analyses, mathematical models, simulations and related studies in PubMed. (nih.gov)
- The HSRProj search strategy includes Program Evaluation studies in addition to health services research studies focusing on CER. (nih.gov)
- Beginning with 4 of proof-of-concept retrospective CER studies on psychotropic and asthma medication use and side effects with a planned full-scale prospective CER study on treatment of pediatric hypertension, the Comparative Effectiveness Research Through Collaborative Electronic Reporting (CER 2 ) collaborators are developing a platform to advance the methodology of pediatric pharmacoepidemiology. (aappublications.org)
- While there remains a widespread lack of understanding on the potential impact of CER in the U.S. and a reluctance to fully adopt the concept as part of our healthcare system, research studies within this area continue to expand across health conditions. (wikipedia.org)
- The international agencies rely mainly on syntheses of existing studies, rather than prospective research, owing to time and resource constraints. (commonwealthfund.org)
- Conclusions: In this sample of studies examining high priority areas for CE research, less than a quarter are CE studies and the majority is supported by government and nonprofits. (harvard.edu)
- Hywel Williams, Professor of Dermato-Epidemiology and Director of the CEBD said: "The large number of products and product combinations, and the scarcity of comparative studies, has led to disparate guidelines with few recommendations being evidence-based. (healthcanal.com)
- One important element of CER is to ensure that appropriate outcomes are measured in research, so that findings can be compared and contrasted across different studies, and useful evidence can be provided to decision makers. (plos.org)
- Similarly, the priority research topics include studies examining various special population categories, including individuals with rare diseases. (nap.edu)
- Distributed health data networks are currently being planned that could cover millions of people, permitting studies of comparative clinical effectiveness, best practices, diffusion of medical technologies, and quality of care. (annals.org)
- Berger ML, Mamdani M, Atkins D, Johnson ML. Good research practices for comparative effectiveness research: defining, reporting and interpreting nonrandomized studies of treatment effects using secondary data sources: The ISPOR good research practices for retrospective database analysis task force report-Part I. Value Health 2009;12:1044-52. (ispor.org)
- Conclusions: Comparative effectiveness research in the form of nonrandomized studies using secondary databases can be designed with rigorous elements and conducted with sophisticated statistical methods to improve causal inference of treatment effects. (ispor.org)
- Read highlights of our funded research studies' results that are being published in leading medical journals and presented at major scientific meetings. (pcori.org)
- Randomized and non-randomized treatment effectiveness studies frequently include analyses to identify subgroups in which the treatment may be more or less effective. (upenn.edu)
- noteworthy book comparative effectiveness research increases the homepage of a insight to boast studies that would sign the study's chaplaincy. (yanodan.com)
- The purpose of this study was to develop a self-reflective framework to guide clinicians, researchers, and technical implementers in developing prospective CER research studies in Primary Care, and overcoming barriers to implementation and use. (thewinnower.com)
- This framework is intended to be used to develop large-scale, long-term, pragmatic comparative effectiveness studies in Family Practice in Canada. (thewinnower.com)
- Everything we understand about cancer reflects the results of thousands of research studies that provide the answers we need to make informed medical decisions. (facingourrisk.org)
- The vast majority of previous CER consists of systematic reviews of published research studies. (hhs.gov)
- We have comparative effectiveness studies out the wazoo on this issue alone and they would be too numerous to mention here. (blogspot.com)
- In the absence of RCTs, evidence generation will require well-designed cohort studies for comparative effectiveness research (CER) that link detailed clinical information to tumor biology and genomic data. (blogspot.com)
Clinicians6
- Results of its research will be provided to patients and clinicians in ways that are responsive to their needs and interests and easy to understand. (nursingworld.org)
- The Distributed Ambulatory Research in Therapeutics Network (DARTNet) is a federated network of electronic health data from 8 organizations representing more than 500 clinicians and more than 400 000 patients. (nih.gov)
- The proposition that greater involvement of patients, clinicians, and others in the research process could help reorient the clinical research enterprise, reduce clinical uncertainty, and speed adoption of meaningful findings holds great promise, but remains to be tested. (medindia.net)
- In this talk Dr Sanders will describe the overall research agenda of the U.S. Effective Healthcare Program which funds individual researchers, research centers, and academic organizations to work together with Agency for Healthcare Research and Quality (AHRQ) to produce effectiveness and comparative effectiveness research for clinicians, consumers, and policymakers. (warwick.ac.uk)
- It's especially important for comparative effectiveness research because this research is meant primarily to serve patients and their clinicians. (healthjournalism.org)
- The meeting discussions were formulated into five recommendations for researchers, clinicians, and other stakeholders to advance research on how clinical treatment options may influence long-term cognitive decline. (biomedcentral.com)
Conduct comparative effectiveness2
- The United States lacks a system to use routinely collected electronic health record (EHR) clinical data to conduct comparative effectiveness research (CER) on pediatric drug therapeutics and other child health topics. (aappublications.org)
- The National Institutes of Health (NIH) announces the opportunity for investigators and United States (U.S.) institutions/organizations with active NIH research grants to request administrative supplements for the purpose of expanding the numbers of researchers qualified to oversee or conduct comparative effectiveness research (CER). (nih.gov)
Methodology4
- In this dissertation, I develop statistical methods for comparative effectiveness estimation and illustrate the methodology in the context of three different medical devices. (harvard.edu)
- The simple definition of comparative effectiveness research is: a methodology that attempts to frame the delivery of health care by comparing the benefit and harm of available diagnostic, prognostic, and therapeutic strategies in representative patients to define the most effective, safe, and cost-effective approach. (ascopost.com)
- Research plan and methodology The investigators hypothesize that rectal administration of indomethacin is not inferior to placement of a pancreatic duct stent in the prevention of pancreatitis after ERCP in high risk patients. (centerwatch.com)
- Following the proposed research, designs for CER should be done while abiding by robust methodology, maintaining transparency, and effectively translating research into clinical practice. (elsevier.com)
Investment in comparative effectiveness research1
- Background: The $1.1 billion investment in comparative effectiveness research will reshape the evidence-base supporting decisions about treatment effectiveness, safety, and cost. (harvard.edu)
Study25
- Participate in a research study - such as an online or in-person focus group. (arthritis.org)
- The 2009 American Recovery and Reinvestment Act designated $400 million in discretionary funds to accelerate CER efforts, and among other areas of study, the Institute of Medicine prioritized research comparing different strategies of introducing biologics in the treatment algorithm for inflammatory bowel disease (IBD). (mayoclinic.org)
- Arguably the most well-known IBD effectiveness study is the landmark SONIC trial, which compared early use of infliximab plus azathioprine to monotherapy with either drug in patients naive to corticosteroids, immunomodulators and anti-tumor necrosis factor (anti-TNF) agents. (mayoclinic.org)
- The study of comparative effectiveness research (CER) is composed of measures useful in determining the value of various treatment options to help patients make more informed decisions in their own care. (wikipedia.org)
- Our ultimate goals are to develop upon what is known in the literature and identify areas where additional measures will improve the ability to study the effectiveness and safety of antidepressants in the primary care environment. (aafp.org)
- Comparative Safety Study of Antidepressants-Measure rates of adverse effects to include the most common medical side effects causing treatment discontinuation, and suicidality, including ideation and attempts. (aafp.org)
- Enhancing Electronic Health Record Measurement of Depression Severity and Suicide Ideation: A Distributed Ambulatory Research in Therapeutics Network (DARTNet) Study. (aafp.org)
- The authors drew on their experience as senior technical and administrative staff involved in creating and running comparative effectiveness research agencies in the four countries included in this study. (commonwealthfund.org)
- The study states: "To ensure research activities that truly embrace the definition of CER, the ARRA funds - and subsequent funding to support CER - should flow through a CER coordinating authority directly to grantees, through federal agencies, or both. (managedcaremag.com)
- This newly-approved study, titled "The comparative effectiveness and safety of antidepressants for the treatment of depression in nursing home residents", will apply methods from comparative effectiveness research , pharmacoepidemiology , and biomedical informatics. (pitt.edu)
- This article presents an overview of DARTNet, explains the contributions of DARTNet to the field of comparative effectiveness research, and summarizes the initial research study and lessons learned. (annals.org)
- EHR use in pharmacotherapy comparative effectiveness research creates specific challenges and study limitations. (rti.org)
- A centralized database will be created with the goal of facilitating comparative effectiveness research on asthma outcomes specifically for this study. (biomedcentral.com)
- The purpose of this study was to assess the comparative effectiveness of allopurinol versus febuxostat for preventing incident dementia in older adults. (biomedcentral.com)
- In ALI, CD4-positive to these preferences is the particular methods in comparative of differentiation cells allowed in the vomiting, study, and proliferation of crucial and crucial navigation getting to infected dependent assassination. (thw-huenfeld.de)
- ObjectiveThe ENGAGE CVD (Effectiveness of Gastric Bypass versus Gastric Sleeve for Cardiovascular Disease) cohort study aimed to provide population-based, comprehensive, rigorous evidence for clinical and policy decision making regarding the choice between gastric bypass and gastric sleeve for overall cardiovascular disease (CVD) risk reduction, risk factor remission, and safety. (doaj.org)
- Although this type of research is overall more cost-effective, there are significant upfront costs in creating the initial study infrastructure that private vendors are unlikely to bear themselves. (thewinnower.com)
- The Depression Clinical & Research Program (DCRP) at Massachusetts General Hospital is considered one of the leading centers for the study of unipolar depressive disorders worldwide. (massgeneral.org)
- The Depression Clinical and Research Program (DCRP), under the direction of David Mischoulon, MD, PhD , is a leader worldwide in the study of unipolar depressive disorders. (massgeneral.org)
- You may be eligible to participate in a research study at Mass General. (massgeneral.org)
- The objective of this study was to compare the effectiveness of vancomycin and linezolid in a national cohort of hospitalized veterans with HCAP. (biomedcentral.com)
- This study was approved by the Institutional Review Board of The University of Texas Health Science Center at San Antonio and the South Texas Veterans Health Care System Research and Development committee. (biomedcentral.com)
- In our real-world comparative effectiveness study among obese patients with suspected MRSA pneumonia, linezolid was associated with a significantly lower mortality rate as compared to the vancomycin-treated patients with lower vancomycin MICs. (omicsonline.org)
- State public health programs could screen nearly eight times as many individuals and prevent nearly twice as many CRC cases by using fecal immunochemical testing, or FIT, instead of colonoscopies, finds a new study in Health Services Research . (cfah.org)
- Neurosurgery scientists also study the presence and roles of stem-like cells in brain tumors, research that is already suggesting ways to inhibit brain tumor growth and destroy tumors. (stanford.edu)
Findings3
- and pursue transparency in our research engagements through our commitment to the open publication of our research findings and recommendations, disclosure of the source of funding of published research, and policies to ensure intellectual independence. (rand.org)
- The money has primarily funded research and helped facilitate getting findings to the patients, doctors, and others who can use them. (gao.gov)
- This Report, the first of three reported in this issue of the journal, addressed issues of framing the research question and reporting and interpreting findings. (ispor.org)
Compares2
- Comparative effectiveness usually compares two or more types of treatment, such as different drugs, for the same disease. (sciencebasedmedicine.org)
- Critics of research that ultimately compares an outcome based on a better average value in an intervention group compared to an average value in the comparison group have a point. (blogspot.com)
Patients19
- It will commission research to provide information about the best available evidence to help patients and their health care providers make more informed decisions. (nursingworld.org)
- By linking electronic health records, laboratory and imaging data, and administrative data from diverse and geographically disparate patients, DARTNet provides important new insight into the comparative effectiveness of oral diabetes medications, and it is ready for expansion to further enable effectiveness research. (nih.gov)
- New models of shared decision making promise to bring greater emphasis to informed patient choice for "preference-sensitive" care, improving quality, safety, and effectiveness of health care by providing both patients and their health care providers with the evidence to assist in informed decision making. (wikipedia.org)
- The institute's first funding announcement solicited projects focused on methods for engaging patients and other stakeholders in all aspects of the research process," Dr. Beal and colleagues write. (medindia.net)
- Applicants will be instructed to explain how their proposed research aligns with the statutory criteria and to describe how patients and other stakeholders will be engaged in and benefit from the research. (medindia.net)
- This research can help patients, doctors, and others make decisions to improve health care. (gao.gov)
- In Australia, France, Germany, and the U.K., comparative effectiveness research is driven by demand for information by those making health care policy and practice decisions, including public and private payers, patients, clinical professionals, and policymakers. (commonwealthfund.org)
- HDBuzz is a patient organization that exists solely to provide news stories about clinical and basic research in the HD field for HD patients and those at risk for HD. (cfah.org)
- The Company's novel pipeline is based on Nobel Prize winning research and includes four differentiated investigational drug candidates: TRV250 for the acute treatment of migraine, TRV734 for maintenance treatment of opioid use disorder, TRV045 for diabetic neuropathic pain and epilepsy, and TRV027 for acute respiratory distress syndrome and abnormal blood clotting in COVID-19 patients. (biospace.com)
- But do we know which subset of patients each one of those is best suited to, and what is the differential effectiveness? (managedcaremag.com)
- The Institute for Clinical and Economic Review (ICER) on Monday announced its plans to analyze the comparative clinical effectiveness and value of Novartis' canakinumab to reduce cardiovascular risk in patients diagnosed with atherosclerosis. (healtheconomics.com)
- While this will certainly delay enrollment of patients into this trial, it also serves as a harbinger for the penurious nature of future government funding for comparative effectiveness research. (blogspot.com)
- Health-care policy experts have made a strong case that comparative effectiveness research is an important instrument for comparing the value of competing strategies so that patients, providers, and policy makers can be offered appropriate recommendations for optimal care. (ascopost.com)
- Purpose - Little is known about the comparative effects of common oral antidiabetic drugs ([OADs] metformin, sulfonylureas, or thiazolidinediones [THZs]) on chronic kidney disease (CKD) outcomes in patients newly diagnosed with type 2 diabetes (T2DM) and followed in community primary care practices. (rti.org)
- Objectives: Health insurers, physicians, and patients worldwide need information on the comparative effectiveness and safety of prescription drugs in routine care. (ispor.org)
- Clinical research is based on the clustering of detectable patient outcomes around the mean, while smaller numbers of patients in both groups may get a lot better or worse. (blogspot.com)
- All of these arguments are reduced to mere chatter, though, if comparative effectiveness research doesn't result in physicians altering how they treat their individual patients. (freethesaurus.com)
- Some registries also allow researchers to contact and inform enrolled patients of new research opportunities. (facingourrisk.org)
- Methicillin-Resistant Staphylococcus aureus (MRSA) has become a leading cause of pneumonia in the United States and there is limited data on treatment outcomes in obese patients.We evaluated the effectiveness of linezolid compared to vancomycin for the treatment of MRSA pneumonia in a national cohort of obese Veterans. (omicsonline.org)
Practices2
- The purpose of the Agency is to enhance the quality, appropriateness, and effectiveness of health services, and access to such services, through the establishment of a broad base of scientific research and through the promotion of improvements in clinical and health system practices, including the prevention of diseases and other health conditions. (house.gov)
- And, although our research themes vary from lab to lab, they are all focused on aspects of disease and injury that can be investigated at the bench - and they all have clear implications for practices in the clinic and operating room. (stanford.edu)
Policymakers1
- While Australia, France, Germany, and the U.K. have developed comparative effectiveness research agencies to suit their unique circumstances, the four agencies share common features that should be carefully considered by U.S. policymakers. (commonwealthfund.org)
Data9
- This Special Article describes the creation and details of a network of EHR networks devised to use clinical data in EHRs for conducting CER, led by the American Academy of Pediatrics Pediatric Research in Office Settings (PROS). (aappublications.org)
- Approximately $106 million in commitments to date are for PCORnet, a data research network aimed at improving the capacity for and speed of conducting CER. (gao.gov)
- Comparative Effectiveness of Treatment for Major Depression-Utilize commercially available national claims data to evaluate the responsiveness and remission rates for major depression treatment and inform and expand knowledge on depression care. (aafp.org)
- and coordinate with relevant federal health programs to build data capacity for this research. (gao.gov)
- The research will mainly be based on data from Swedish population and health data registers. (ki.se)
- In other words, are we mature enough to use comparative effectiveness data to make tough decisions about what we will and won't pay for? (thehealthcareblog.com)
- The research network coordinating this project includes hospitals, urgent care centers, and outpatient clinics within Carolinas Healthcare System that share a common electronic medical record and billing system allowing for rapid collection of clinical and demographic data. (biomedcentral.com)
- In this paper we describe lessons learned from the creation of Basic Stand Alone (BSA) Public Use Files (PUFs) for the Comparative Effectiveness Research Public Use Files Data Pilot Project (CER-PUF). (uni-muenchen.de)
- A three-year $10.5 million federal grant awarded in December to help speed up mental health research will rely heavily on data from members of six Kaiser Permanente regions, including Kaiser Permanente Northern California. (kaiserpermanente.org)
Inform3
- Additionally, some health conditions, such as for prostate cancer treatment, lack patient-centered outcomes to inform comparative effectiveness research. (wikipedia.org)
- Other countries' experiences in creating and operating comparative effectiveness research agencies may provide useful lessons to inform these discussions. (commonwealthfund.org)
- The Agency for Healthcare Research and Quality funded the creation of DARTNet through its Developing Evidence to Inform Decisions about Effectiveness Network. (annals.org)
Treatment12
- Comparative effectiveness research (CER) informs health-care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options. (nursingworld.org)
- The core question of comparative effectiveness research is which treatment works best, for whom, and under what circumstances. (wikipedia.org)
- The idea of CER is that researchers and scientists gather evidence and compare surgeries, medical devices, drugs, tests, or health care services, and weigh the effectiveness, benefits, and potential harms of each of these treatment options against one another. (scai.org)
- Compare the effectiveness of treatment strategies for atrial fibrillation including surgery, catheter ablation, and pharmacologic treatment. (managedcaremag.com)
- The focus on the individual patient is described through chapters on patient-centred comparative effectiveness research, individualized treatment, the link with personalized medicine, and incorporating patient and public input for treatment. (springer.com)
- What we would like to see is a great deal more comparative effectiveness research to help reduce the plethora of current therapeutic options for initiation and maintenance treatment. (healthcanal.com)
- Many in the oncology community initially viewed comparative effectiveness research as an overarching government program that would ultimately ration oncologists' treatment options in order to save money. (ascopost.com)
- A direct comparison in the form of a RCT to compare effectiveness of both treatment modalities is required. (centerwatch.com)
- One will provide up to $16 million for research on the best ways to deliver medication-assisted treatment for opioid use disorders to pregnant women. (pcori.org)
- Effectiveness refers to the actual benefit of that treatment in usual care settings in a broad patient population. (asahq.org)
- Every advancement made in treatment, prevention or care has come from research. (facingourrisk.org)
- Fox RJ a Mellen Center for Multiple Sclerosis Treatment and Research , Cleveland Clinic , Cleveland , OH , USA. (unboundmedicine.com)
Safety of antidepressants1
- As part of his training, he is conducting research to compare the effectiveness and safety of antidepressants used to treat elderly adults residing in nursing homes. (pitt.edu)
Researchers5
- The goal of this network is to engage child health researchers from around the United States in participating in collaborative research using the CER 2 database. (aappublications.org)
- By Janet Byron, Senior Communications Specialist, Kaiser Permanente Division of Research In a new video, Kaiser Permanente researchers explain how the Walnut Creek ophthalmology department virtually eliminated a rare, surgery-related infection. (kaiserpermanente.org)
- Participants included researchers with an interest in Primary Care research, technical representatives of EMR vendors, and Family Physicians. (thewinnower.com)
- In the future, researchers will need to clearly outline the business case for vendors to participate in Primary Care research. (thewinnower.com)
- Such a process was long thought to be absent in the brain, but research in the last decade, much of it by Stanford Neurosurgery researchers, has shown neurogenesis to be robust and important to brain function and perhaps to the repair of the brain after injury. (stanford.edu)
Methods in comparative effectiveness research11
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Goal of comparative effectiveness research1
- The goal of comparative effectiveness research is to improve health care while dealing with the seemingly ever-rising cost. (ajnr.org)
Assess1
- The Institute for Clinical and Economic Review (ICER) will assess the comparative clinical effectiveness and value of elagolix (AbbVie) for management of endometriosis with associated pain. (healtheconomics.com)
Practice5
- This type of research is intended to foster evidence-based changes in practice that reduce costs and improve patient care. (mayoclinic.org)
- She will specifically focus on the comparative effectiveness research (CER) taking place at Duke University as part of the Evidence-based Practice Center. (warwick.ac.uk)
- They are optimistic it will, because there are some examples of the rapid translation of clinical research into mainstream practice. (blogspot.com)
- Understanding and improving the prognosis of a disease or health condition is a priority in clinical research and practice. (bmj.com)
- The DCRP's research has informed clinical practice and contributed to the development of new standards of care for depression. (massgeneral.org)
Decisions6
- This work aims to: (1) develop and refine topics for CERs that are informative to stakeholder decisional needs, (2) conduct CERs with systematic and transparent methods, and to (3) identify and explicate future research needs that are important to answering real-world healthcare decisions. (warwick.ac.uk)
- In the four countries, comparative effectiveness research agencies produce information that affects clinical and health policy decisions. (commonwealthfund.org)
- Blue Cross Blue Shield Association Chief Medical Office Trent Haywood discussed comparative effectiveness research and how it could facilitate personalized decisions on health care. (healtheconomics.com)
- After a prolonged debate over government-sponsored comparative effectiveness research, Congress decided to authorize it in the Affordable Care Act, but to strictly forbid CMS from considering the results in coverage decisions. (physicianspractice.com)
- NICE provides an important reminder of how much lower other countries pay for drugs when comparative effectiveness and value-based pricing are integrated into public drug coverage decisions. (lse.ac.uk)
- As more people participate in research, scientists and health care providers can develop new evidence-based guidelines to help people make health care decisions. (facingourrisk.org)
DARTNet2
- DARTNet was designed to increase knowledge of the comparative effectiveness of prescription medications and medical devices. (nih.gov)
- Key clinical information traditionally missing in comparative effectiveness research is now available through DARTNet. (annals.org)
Challenges5
- The RAND Corporation is a research organization that develops solutions to public policy challenges to help make communities throughout the world safer and more secure, healthier and more prosperous. (rand.org)
- Medical devices bring a unique set of challenges for comparative effectiveness research. (harvard.edu)
- However, while acceptance of comparative effectiveness research is growing, operational as well as political and cultural challenges remain. (ascopost.com)
- Multiple Imputation for Disclosure Limitation: Future Research Challenges. (uni-muenchen.de)
- Special series on comparative effectiveness research: challenges to real-world solutions to quality improvement in personalized medicine. (blogspot.com)
Institute9
- The National Institute for Health and Clinical Excellence of the United Kingdom is a noteworthy example of comparative effectiveness research in action. (ajnr.org)
- The Institute for Clinical and Economic Review recently released a Draft Evidence Report assessing the comparative clinical effectiveness and value of emicizumab. (healtheconomics.com)
- This has prompted the Institute of Medicine in the USA to target comparative-effectiveness research on acne therapy as one of the top 100 targets for national research. (healthcanal.com)
- This work was funded by the NIHR (National Institute for Health Research), grant number NF-SI_0513-10025. (plos.org)
- As explained in detail in Chapter 1 , the Institute of Medicine (IOM) committee's statement of task charged the committee with developing a list of priority comparative effectiveness research (CER) topics and presenting those recommendations for the Secretary to consider. (nap.edu)
- Also according to the Washington Post article, "Experts at the Institute of Medicine will spend the next several months prioritizing the research. (honestmedicine.com)
- The directors of the Coordinating Center will be Richard Platt, MD, professor and chair of the Harvard Medical School Department of Population Medicine at the Harvard Pilgrim Health Care Institute in Boston, and Robert Califf, MD, vice chancellor for clinical and translational research, director of the Duke Translational Medicine Institute, and professor of Medicine in the Division of Cardiology at the Duke University Medical Center in Durham, N.C. (healthcareitnews.com)
- Additional expertise is provided by staff from AcademyHealth, Brookings Institution, Center for Democracy and Technology, Center for Medical Technology Policy, Group Health Research Institute and Johns Hopkins University . (healthcareitnews.com)
- The California Institute for Regenerative Medicine hosts Dr. Gary Steinberg in an 'Ask the Expert' Facebook Live event about his clinical research on the use of stem cell therapy for stroke. (stanford.edu)
Institutes4
- These funds are divided among the National Institutes of Health, Department of Health and Human Services, and Agency for Healthcare Research and Quality. (asahq.org)
- He is a member of the National Institutes of Health's Comparative Effectiveness Research Steering Committee and was a previous vice chair of the Medicare Evidence Development and Coverage Advisory Committee. (freethesaurus.com)
- It has a history of managing and coordinating similar initiatives, including the U.S. Food and Drug Administration's Mini Sentinel Program and the National Institutes of Health's Health Care Systems Research Collaboratory. (healthcareitnews.com)
- 1 billion in funding for CER, channeled through the National Institutes of Health (NIH), the Department of Health and Human Services (HHS), and the Agency for Healthcare Research and Quality (AHRQ). (hhs.gov)
Oversee1
- This group will oversee the application of comparative effectiveness research in health care reform. (medicallessons.net)
Adoption1
- This follows the region-wide adoption of an integrated telemedicine program, according to new research published December 15 in the journal Stroke. (kaiserpermanente.org)
California1
- The editors-in-chief are Sheldon Greenfield (University of California, Irvine) and Eugene Rich (Mathematica Policy Research). (wikipedia.org)
Search3
- The Costs and Cost Analysis search strategy is based on the Health Services Research query on Costs (Broad scope). (nih.gov)
- The Comparative Effectiveness Research as Topic search strategy has been designed to retrieve citations "about" CER. (nih.gov)
- In 2013, the first comprehensive search for COS in health research was conducted to ensure that the database content was comprehensive and up-to-date [ 4 ]. (plos.org)
Epidemiologic and health services1
- The Kaiser Permanente Division of Research conducts, publishes, and disseminates epidemiologic and health services research to improve the health and medical care of Kaiser Permanente members and society at large. (kaiserpermanente.org)
Strategies3
- It provides general guidance and suggestions for engagement compliance and engagement strategies in the research process. (pcori.org)
- The Alzheimer's Drug Discovery Foundation convened an advisory panel to discuss the existing evidence and to recommend strategies to accelerate the development of comparative effectiveness research on how choices in the clinical care of common chronic diseases may protect from cognitive decline and dementia. (biomedcentral.com)
- Comparative analysis of proposed strategies for incorporating biologic factors into breast cancer staging. (utmb.edu)
Constraint1
- Remove constraint Titles: Comparative effectiveness: what's at stake for consumers? (nih.gov)
Subset1
- This is methods in comparative effectiveness subset( from the Latin for eosinophil correlation). (thw-huenfeld.de)
Medical7
- What this means," says I. Steven Udvarhelyi, MD, senior vice president and chief medical officer at Independence Blue Cross, "is that the experts that sat on the panel with me looking at the available research said that we do not have enough information that tells us the relative effectiveness. (managedcaremag.com)
- Comparative effectiveness also can compare types of surgery or other kinds of medical procedures and tests. (sciencebasedmedicine.org)
- The National Pharmaceutical Council (NPC) is a health policy research organization dedicated to the advancement of good evidence and science, and to fostering an environment in the United States that supports medical innovation. (npcnow.org)
- Participating in research allows people to contribute to medical knowledge and offers the opportunity to receive cutting-edge care. (facingourrisk.org)
- Experts design and conduct many different types of medical research to answer different types of questions. (facingourrisk.org)
- Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields. (omicsonline.org)
- As the number of patient centered medical homes has increased, a new report in the journal Health Services Research finds the model offers a promising option to reduce health care costs and utilization of some health care services. (cfah.org)
Care14
- This research recognizes that the patient's voice should be heard in the health care decision making process. (nursingworld.org)
- AHRQ is dedicated to improving the quality, safety, efficiency, and effectiveness of health care for all Americans. (nursingworld.org)
- The Agency for Healthcare Research and Quality (AHRQ) is a federal agency focused on health care quality. (wikipedia.org)
- By contrast, comparative effectiveness legislation under consideration in the U.S. Senate explicitly separates the generation of knowledge from health care decision-making. (commonwealthfund.org)
- Gruman: Where do you see comparative effectiveness research (CER) fitting in the effort to improve the effectiveness of health care? (cfah.org)
- First off, it is important to note that comparative effectiveness research has been applied across the spectrum of cancer needs from prevention, screening, diagnosis, all the way through supportive care and end-of-life issues. (ascopost.com)
- Linking cost savings with the central mission of comparative effectiveness research has perhaps given the impression to many in the oncology community that they are going to be overly scrutinized about the costs of the care they deliver. (ascopost.com)
- Skinner, J.A., Weinstein, M.C. "Comparative Effectiveness and Health Care Spending - Implications for Reform. (investigatorawards.org)
- The Disease Management Care Blog found three predictable articles on comparative effectiveness research (CER) in the latest [May 17 Volume 360 (19)] New England Journal of Medicine . (blogspot.com)
- Background: Comparative effectiveness research (CER) has come to remain at the forefront of political and scientific debates of health care. (elsevier.com)
- There are currently multiple barriers to conducting EMR-enabled research in Primary Care. (thewinnower.com)
- While this has resulted in improved clinical efficiencies and patient care [Canada Health Infoway (2013)], unfortunately these improvements have not been paralleled in the realm of Primary Care research. (thewinnower.com)
- The clinical program delivers care outside of the research setting to people with depressive disorders. (massgeneral.org)
- Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond. (blogspot.com)