Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.Diagnostic and Statistical Manual of Mental Disorders: Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)Anxiety Disorders: Persistent and disabling ANXIETY.Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.United StatesPrevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Diagnosis, Dual (Psychiatry): The co-existence of a substance abuse disorder with a psychiatric disorder. The diagnostic principle is based on the fact that it has been found often that chemically dependent patients also have psychiatric problems of various degrees of severity.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Risk Adjustment: The use of severity-of-illness measures, such as age, to estimate the risk (measurable or predictable chance of loss, injury or death) to which a patient is subject before receiving some health care intervention. This adjustment allows comparison of performance and quality across organizations, practitioners, and communities. (from JCAHO, Lexikon, 1994)Substance-Related Disorders: Disorders related to substance abuse.Psychiatric Status Rating Scales: Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.Phobic Disorders: Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Health Surveys: A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Depressive Disorder, Major: Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.Personality Disorders: A major deviation from normal patterns of behavior.Impulse Control Disorders: Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.Interview, Psychological: A directed conversation aimed at eliciting information for psychiatric diagnosis, evaluation, treatment planning, etc. The interview may be conducted by a social worker or psychologist.Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Depression: Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.Hospitalization: The confinement of a patient in a hospital.Stress Disorders, Post-Traumatic: A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.Veterans: Former members of the armed services.Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.Conduct Disorder: A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.Proportional Hazards Models: Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.Medicare: Federal program, created by Public Law 89-97, Title XVIII-Health Insurance for the Aged, a 1965 amendment to the Social Security Act, that provides health insurance benefits to persons over the age of 65 and others eligible for Social Security benefits. It consists of two separate but coordinated programs: hospital insurance (MEDICARE PART A) and supplementary medical insurance (MEDICARE PART B). (Hospital Administration Terminology, AHA, 2d ed and A Discursive Dictionary of Health Care, US House of Representatives, 1976)Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Age of Onset: The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.DenmarkLongitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Hospital Mortality: A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.International Classification of Diseases: A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Diseases in Twins: Disorders affecting TWINS, one or both, at any age.Health Status: The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.Anxiety: Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.Length of Stay: The period of confinement of a patient to a hospital or other health facility.Outcome Assessment (Health Care): Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).Health Status Indicators: The measurement of the health status for a given population using a variety of indices, including morbidity, mortality, and available health resources.Netherlands: Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, Sint Maarten, formerly included in the NETHERLANDS ANTILLES.Activities of Daily Living: The performance of the basic activities of self care, such as dressing, ambulation, or eating.Disability Evaluation: Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Obsessive Hoarding: Persistent difficulty discarding or parting with possessions, regardless of the value of these possessions. Epidemiological studies suggest that hoarding occurs in 2-5% of the population and can lead to substantial distress and disability, as well as serious public health consequences.Eating Disorders: A group of disorders characterized by physiological and psychological disturbances in appetite or food intake.Agoraphobia: Obsessive, persistent, intense fear of open places.Geriatric Assessment: Evaluation of the level of physical, physiological, or mental functioning in the older population group.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Somatoform Disorders: Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by a another medical condition, by the direct effects of a substance, or by another mental disorder. The symptoms must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)Attention Deficit and Disruptive Behavior Disorders: Includes two similar disorders: oppositional defiant disorder and CONDUCT DISORDERS. Symptoms occurring in children with these disorders include: defiance of authority figures, angry outbursts, and other antisocial behaviors.Peritoneal Dialysis: Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Antisocial Personality Disorder: A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994)Hypochondriasis: Preoccupation with the fear of having, or the idea that one has, a serious disease based on the person's misinterpretation of bodily symptoms. (APA, DSM-IV)SEER Program: A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From National Cancer Institute, NIH Publication No. 91-3074, October 1990)United States Department of Veterans Affairs: A cabinet department in the Executive Branch of the United States Government concerned with overall planning, promoting, and administering programs pertaining to VETERANS. It was established March 15, 1989 as a Cabinet-level position.Health Services: Services for the diagnosis and treatment of disease and the maintenance of health.Insanity Defense: A legal concept that an accused is not criminally responsible if, at the time of committing the act, the person was laboring under such a defect of reason from disease of the mind as not to know the nature and quality of the act done or if the act was known, to not have known that what was done was wrong. (From Black's Law Dictionary, 6th ed)Suicide, Attempted: The unsuccessful attempt to kill oneself.Cost of Illness: The personal cost of acute or chronic disease. The cost to the patient may be an economic, social, or psychological cost or personal loss to self, family, or immediate community. The cost of illness may be reflected in absenteeism, productivity, response to treatment, peace of mind, or QUALITY OF LIFE. It differs from HEALTH CARE COSTS, meaning the societal cost of providing services related to the delivery of health care, rather than personal impact on individuals.Patient Selection: Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Cystectomy: Used for excision of the urinary bladder.AlabamaSpain: Parliamentary democracy located between France on the northeast and Portugual on the west and bordered by the Atlantic Ocean and the Mediterranean Sea.Demography: Statistical interpretation and description of a population with reference to distribution, composition, or structure.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Medical Records: Recording of pertinent information concerning patient's illness or illnesses.Personality Assessment: The determination and evaluation of personality attributes by interviews, observations, tests, or scales. Articles concerning personality measurement are considered to be within scope of this term.Psychotropic Drugs: A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).Psychopathology: The study of significant causes and processes in the development of mental illness.Hospitals, Veterans: Hospitals providing medical care to veterans of wars.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Insurance Claim Review: Review of claims by insurance companies to determine liability and amount of payment for various services. The review may also include determination of eligibility of the claimant or beneficiary or of the provider of the benefit; determination that the benefit is covered or not payable under another policy; or determination that the service was necessary and of reasonable cost and quality.Inpatients: Persons admitted to health facilities which provide board and room, for the purpose of observation, care, diagnosis or treatment.Primary Health Care: Care which provides integrated, accessible health care services by clinicians who are accountable for addressing a large majority of personal health care needs, developing a sustained partnership with patients, and practicing in the context of family and community. (JAMA 1995;273(3):192)Age Distribution: The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Gambling: An activity distinguished primarily by an element of risk in trying to obtain a desired goal, e.g., playing a game of chance for money.Renal Replacement Therapy: Procedures which temporarily or permanently remedy insufficient cleansing of body fluids by the kidneys.Antidepressive Agents: Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Health Care Costs: The actual costs of providing services related to the delivery of health care, including the costs of procedures, therapies, and medications. It is differentiated from HEALTH EXPENDITURES, which refers to the amount of money paid for the services, and from fees, which refers to the amount charged, regardless of cost.Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.European Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Europe.Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Frail Elderly: Older adults or aged individuals who are lacking in general strength and are unusually susceptible to disease or to other infirmity.Borderline Personality Disorder: A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Alcohol-Related Disorders: Disorders related to or resulting from abuse or mis-use of alcohol.Dysthymic Disorder: Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. (DSM-IV)Headache Disorders: Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)Diagnosis-Related Groups: A system for classifying patient care by relating common characteristics such as diagnosis, treatment, and age to an expected consumption of hospital resources and length of stay. Its purpose is to provide a framework for specifying case mix and to reduce hospital costs and reimbursements and it forms the cornerstone of the prospective payment system.Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)Patient Readmission: Subsequent admissions of a patient to a hospital or other health care institution for treatment.Dyscalculia: Impaired ability in numerical concepts. These inabilities arise as a result of primary neurological lesion, are syndromic (e.g., GERSTMANN SYNDROME ) or acquired due to brain damage.Personality: Behavior-response patterns that characterize the individual.Genetics, Behavioral: The experimental study of the relationship between the genotype of an organism and its behavior. The scope includes the effects of genes on simple sensory processes to complex organization of the nervous system.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Outpatients: Persons who receive ambulatory care at an outpatient department or clinic without room and board being provided.Mental Health Services: Organized services to provide mental health care.Personality Inventory: Check list, usually to be filled out by a person about himself, consisting of many statements about personal characteristics which the subject checks.Mortality, Premature: Deaths that occur before LIFE EXPECTANCY is reached within a given population.Refusal to Treat: Refusal of the health professional to initiate or continue treatment of a patient or group of patients. The refusal can be based on any reason. The concept is differentiated from PATIENT REFUSAL OF TREATMENT see TREATMENT REFUSAL which originates with the patient and not the health professional.GermanyPolypharmacy: The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).Karnofsky Performance Status: A performance measure for rating the ability of a person to perform usual activities, evaluating a patient's progress after a therapeutic procedure, and determining a patient's suitability for therapy. It is used most commonly in the prognosis of cancer therapy, usually after chemotherapy and customarily administered before and after therapy. It was named for Dr. David A. Karnofsky, an American specialist in cancer chemotherapy.Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.Confidence Intervals: A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.Models, Psychological: Theoretical representations that simulate psychological processes and/or social processes. These include the use of mathematical equations, computers, and other electronic equipment.Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Health Services for the Aged: Services for the diagnosis and treatment of diseases in the aged and the maintenance of health in the elderly.Psychophysiologic Disorders: A group of disorders characterized by physical symptoms that are affected by emotional factors and involve a single organ system, usually under AUTONOMIC NERVOUS SYSTEM control. (American Psychiatric Glossary, 1988)Elimination Disorders: Excretory-related psychiatric disorders usually diagnosed in infancy or childhood.Life Change Events: Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living.Physician's Practice Patterns: Patterns of practice related to diagnosis and treatment as especially influenced by cost of the service requested and provided.Linear Models: Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.Psychotherapy: A generic term for the treatment of mental illness or emotional disturbances primarily by verbal or nonverbal communication.Patient Discharge: The administrative process of discharging the patient, alive or dead, from hospitals or other health facilities.Epidemiologic Methods: Research techniques that focus on study designs and data gathering methods in human and animal populations.Suicide: The act of killing oneself.Disabled Persons: Persons with physical or mental disabilities that affect or limit their activities of daily living and that may require special accommodations.Compulsive Personality Disorder: Disorder characterized by an emotionally constricted manner that is unduly conventional, serious, formal, and stingy, by preoccupation with trivial details, rules, order, organization, schedules, and lists, by stubborn insistence on having things one's own way without regard for the effects on others, by poor interpersonal relationships, and by indecisiveness due to fear of making mistakes.Prostatic Neoplasms: Tumors or cancer of the PROSTATE.Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)Lithium Compounds: Inorganic compounds that contain lithium as an integral part of the molecule.Psychometrics: Assessment of psychological variables by the application of mathematical procedures.Humeral Head: The portion of the upper rounded extremity fitting into the glenoid cavity of the SCAPULA. (from Stedman, 27th ed)Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.Tic Disorders: Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)Bulimia: Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as "ox hunger".Patient Acceptance of Health Care: The seeking and acceptance by patients of health service.Affective Symptoms: Mood or emotional responses dissonant with or inappropriate to the behavior and/or stimulus.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Croatia: Created 7 April 1992 as a result of the division of Yugoslavia.Tobacco Use Disorder: Tobacco used to the detriment of a person's health or social functioning. Tobacco dependence is included.Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Cognition Disorders: Disturbances in mental processes related to learning, thinking, reasoning, and judgment.MinnesotaCompulsive Behavior: The behavior of performing an act persistently and repetitively without it leading to reward or pleasure. The act is usually a small, circumscribed behavior, almost ritualistic, yet not pathologically disturbing. Examples of compulsive behavior include twirling of hair, checking something constantly, not wanting pennies in change, straightening tilted pictures, etc.PennsylvaniaSaskatchewan: A province of Canada, lying between the provinces of Alberta and Manitoba. Its capital is Regina. It is entirely a plains region with prairie in the south and wooded country with many lakes and swamps in the north. The name was taken from the Saskatchewan River from the Cree name Kisiskatchewani Sipi, meaning rapid-flowing river. (From Webster's New Geographical Dictionary, 1988, p1083 & Room, Brewer's Dictionary of Names, 1992, p486)Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Life Expectancy: Based on known statistical data, the number of years which any person of a given age may reasonably expected to live.Health Services Research: The integration of epidemiologic, sociological, economic, and other analytic sciences in the study of health services. Health services research is usually concerned with relationships between need, demand, supply, use, and outcome of health services. The aim of the research is evaluation, particularly in terms of structure, process, output, and outcome. (From Last, Dictionary of Epidemiology, 2d ed)Manitoba: A province of Canada, lying between the provinces of Saskatchewan and Ontario. Its capital is Winnipeg. Taking its name from Lake Manitoba, itself named for one of its islands, the name derived from Algonquian Manitou, great spirit. (From Webster's New Geographical Dictionary, 1988, p724 & Room, Brewer's Dictionary of Names, 1992, p332)Medicare Part A: The compulsory portion of Medicare that is known as the Hospital Insurance Program. All persons 65 years and older who are entitled to benefits under the Old Age, Survivors, Disability and Health Insurance Program or railroad retirement, persons under the age of 65 who have been eligible for disability for more than two years, and insured workers (and their dependents) requiring renal dialysis or kidney transplantation are automatically enrolled in Medicare Part A.Utilization Review: An organized procedure carried out through committees to review admissions, duration of stay, professional services furnished, and to evaluate the medical necessity of those services and promote their most efficient use.Referral and Consultation: The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.Neurotic Disorders: Disorders in which the symptoms are distressing to the individual and recognized by him or her as being unacceptable. Social relationships may be greatly affected but usually remain within acceptable limits. The disturbance is relatively enduring or recurrent without treatment.Self Report: Method for obtaining information through verbal responses, written or oral, from subjects.Psychoneuroimmunology: The field concerned with the interrelationship between the brain, behavior and the immune system. Neuropsychologic, neuroanatomic and psychosocial studies have demonstrated their role in accentuating or diminishing immune/allergic responses.Arthroplasty, Replacement, Hip: Replacement of the hip joint.Survivors: Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.Diabetes Complications: Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.New JerseyAfrican Americans: Persons living in the United States having origins in any of the black groups of Africa.Asperger Syndrome: A disorder beginning in childhood whose essential features are persistent impairment in reciprocal social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities. These symptoms may limit or impair everyday functioning. (From DSM-5)Hemodialysis Units, Hospital: Hospital units in which care is provided the hemodialysis patient. This includes hemodialysis centers in hospitals.Geriatrics: The branch of medicine concerned with the physiological and pathological aspects of the aged, including the clinical problems of senescence and senility.Acting Out: Expressing unconscious emotional conflicts or feelings, often of hostility or love, through overt behavior.Anxiety, Separation: Anxiety experienced by an individual upon separation from a person or object of particular significance to the individual.Practice Guidelines as Topic: Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.Clinical Coding: Process of substituting a symbol or code for a term such as a diagnosis or procedure. (from Slee's Health Care Terms, 3d ed.)Forecasting: The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.Australia: The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.Medical Record Linkage: The creation and maintenance of medical and vital records in multiple institutions in a manner that will facilitate the combined use of the records of identified individuals.

Correlates of sexually transmitted bacterial infections among U.S. women in 1995. (1/12384)

CONTEXT: Sexually transmitted diseases (STDs) of bacterial origin such as gonorrhea and chlamydial infection can lead to pelvic inflammatory disease (PID) and infertility. Identifying behaviors and characteristics associated with infection may assist in preventing these often asymptomatic diseases and their sequelae. METHODS: Data from 9,882 sexually active women who participated in the 1995 National Survey of Family Growth describe the characteristics of women who report a history of infection with a bacterial STD or of treatment for PID. Multivariate analysis is used to determine which demographic characteristics and sexual and health-related behaviors affect the likelihood of infection or the occurrence of complications. RESULTS: Overall, 6% of sexually active women reported a history of a bacterial STD, and 8% reported a history of PID. Women who first had sexual intercourse before age 15 were nearly four times as likely to report a bacterial STD, and more than twice as likely to report PID, as were women who first had sex after age 18. Having more than five lifetime sexual partners also was associated with both having an STD and having PID. PID was more common among women reporting a history of a bacterial STD (23%) than among women who reported no such history (7%). In multivariate analyses, age, race, age at first intercourse and lifetime number of sexual partners had a significant effect on the risk of a bacterial STD. Education, age, a history of IUD use, douching and a history of a bacterial STD had a significant impact on the risk of PID, but early onset of intercourse did not, and lifetime number of partners had only a marginal effect. CONCLUSIONS: The pattern of characteristics and behaviors that place women at risk of infection with bacterial STDs is not uniform among groups of women. Further, the level of self-reported PID would suggest higher rates of gonorrhea and chlamydial infection than reported.  (+info)

Prevalence and clinical outcome associated with preexisting malnutrition in acute renal failure: a prospective cohort study. (2/12384)

Malnutrition is a frequent finding in hospitalized patients and is associated with an increased risk of subsequent in-hospital morbidity and mortality. Both prevalence and prognostic relevance of preexisting malnutrition in patients referred to nephrology wards for acute renal failure (ARF) are still unknown. This study tests the hypothesis that malnutrition is frequent in such clinical setting, and is associated with excess in-hospital morbidity and mortality. A prospective cohort of 309 patients admitted to a renal intermediate care unit during a 42-mo period with ARF diagnosis was studied. Patients with malnutrition were identified at admission by the Subjective Global Assessment of nutritional status method (SGA); nutritional status was also evaluated by anthropometric, biochemical, and immunologic parameters. Outcome measures included in-hospital mortality and morbidity, and use of health care resources. In-hospital mortality was 39% (120 of 309); renal replacement therapies (hemodialysis or continuous hemofiltration) were performed in 67% of patients (206 of 309); APACHE II score was 23.1+/-8.2 (range, 10 to 52). Severe malnutrition by SGA was found in 42% of patients with ARF; anthropometric, biochemical, and immunologic nutritional indexes were significantly reduced in this group compared with patients with normal nutritional status. Severely malnourished patients, as compared to patients with normal nutritional status, had significantly increased morbidity for sepsis (odds ratio [OR] 2.88; 95% confidence interval [CI], 1.53 to 5.42, P < 0.001), septic shock (OR 4.05; 95% CI, 1.46 to 11.28, P < 0.01), hemorrhage (OR 2.98; 95% CI, 1.45 to 6.13, P < 0.01), intestinal occlusion (OR 5.57; 95% CI, 1.57 to 19.74, P < 0.01), cardiac dysrhythmia (OR 2.29; 95% CI, 1.36 to 3.85, P < 0.01), cardiogenic shock (OR 4.39; 95% CI, 1.83 to 10.55, P < .001), and acute respiratory failure with mechanical ventilation need (OR 3.35; 95% CI, 3.35 to 8.74, P < 0.05). Hospital length of stay was significantly increased (P < 0.01), and the presence of severe malnutrition was associated with a significant increase of in-hospital mortality (OR 7.21; 95% CI, 4.08 to 12.73, P < 0.001). Preexisting malnutrition was a statistically significant, independent predictor of in-hospital mortality at multivariable logistic regression analysis both with comorbidities (OR 2.02; 95% CI, 1.50 to 2.71, P < 0.001), and with comorbidities and complications (OR 2.12; 95% CI, 1.61 to 2.89, P < 0.001). Malnutrition is highly prevalent among ARF patients and increases the likelihood of in-hospital death, complications, and use of health care resources.  (+info)

Hematocrit level and associated mortality in hemodialysis patients. (3/12384)

Although a number of clinical studies have shown that increased hematocrits are associated with improved outcomes in terms of cognitive function, reduced left ventricular hypertrophy, increased exercise tolerance, and improved quality of life, the optimal hematocrit level associated with survival has yet to be determined. The association between hematocrit levels and patient mortality was retrospectively studied in a prevalent Medicare hemodialysis cohort on a national scale. All patients survived a 6-mo entry period during which their hematocrit levels were assessed, from July 1 through December 31, 1993, with follow-up from January 1 through December 31, 1994. Patient comorbid conditions relative to clinical events and severity of disease were determined from Medicare claims data and correlated with the entry period hematocrit level. After adjusting for medical diseases, our results showed that patients with hematocrit levels less than 30% had significantly higher risk of all-cause (12 to 33%) and cause-specific death, compared to patients with hematocrits in the 30% to less than 33% range. Without severity of disease adjustment, patients with hematocrit levels of 33% to less than 36% appear to have the lowest risk for all-cause and cardiac mortality. After adjusting for severity of disease, the impact of hematocrit levels of 33% to less than 36% is vulnerable to the patient sample size but also demonstrates a further 4% reduced risk of death. Overall, these findings suggest that sustained increases in hematocrit levels are associated with improved patient survival.  (+info)

A comparison of the use, effectiveness and safety of bezafibrate, gemfibrozil and simvastatin in normal clinical practice using the New Zealand Intensive Medicines Monitoring Programme (IMMP). (4/12384)

AIMS: Because of the importance of treating dyslipidaemia in the prevention of ischaemic heart disease and because patient selection criteria and outcomes in clinical trials do not necessarily reflect what happens in normal clinical practice, we compared outcomes from bezafibrate, gemfibrozil and simvastatin therapy under conditions of normal use. METHODS: A random sample of 200 patients was selected from the New Zealand Intensive Medicines Monitoring Programme's (IMMP) patient cohorts for each drug. Questionnaires sent to prescribers requested information on indications, risk factors for ischaemic heart disease, lipid profiles with changes during treatment and reasons for stopping therapy. RESULTS: 80% of prescribers replied and 83% of these contained useful information. The three groups were similar for age, sex and geographical region, but significantly more patients on bezafibrate had diabetes and/or hypertension than those on gemfibrozil or simvastatin. After treatment and taking the initial measure into account, the changes in serum lipid values were consistent with those generally observed, but with gemfibrozil being significantly less effective than expected. More patients (15.8%S) stopped gemfibrozil because of an inadequate response compared with bezafibrate (5.4%) and simvastatin (1.6%). Gemfibrozil treatment was also withdrawn significantly more frequently due to a possible adverse reaction compared with the other two drugs. CONCLUSIONS: In normal clinical practice in New Zealand gemfibrozil appears less effective and more frequently causes adverse effects leading to withdrawal of treatment than either bezafibrate or simvastatin.  (+info)

Pulmonary embolism: one-year follow-up with echocardiography doppler and five-year survival analysis. (5/12384)

BACKGROUND: The long-term prognosis for patients with pulmonary embolism (PE) is dependent on the underlying disease, degree of pulmonary hypertension (PH), and degree of right ventricular (RV) dysfunction. A precise description of the time course of pulmonary artery pressure (PAsP)/RV function is therefore of importance for the early identification of persistent PH/RV dysfunction in patients treated for acute PE. Other objectives were to identify variables associated with persistent PH/RV dysfunction and to analyze the 5-year survival rate for patients alive 1 month after inclusion. METHODS AND RESULTS: Echocardiography Doppler was performed in 78 patients with acute PE at the time of diagnosis and repeatedly during the next year. A 5-year survival analysis was made. The PAsP decreased exponentially until the beginning of a stable phase, which was 50 mm Hg at the time of diagnosis of acute PE was associated with persistent PH after 1 year. The 5-year mortality rate was associated with underlying disease. Only patients with persistent PH in the stable phase required pulmonary thromboendarterectomy within 5 years. CONCLUSIONS: An echocardiography Doppler investigation performed 6 weeks after diagnosis of acute PE can identify patients with persistent PH/RV dysfunction and may be of value in planning the follow-up and care of these patients.  (+info)

Prostatic intraepithelial neoplasia and apoptosis in benign prostatic hyperplasia before and after the Chernobyl accident in Ukraine. (6/12384)

The prevalence of prostatic intraepithelial neoplasia (PIN) in men who underwent surgery for benign prostatic hyperplasia (BPH) before and after the Chernobyl nuclear accident was studied. BPH samples were obtained by adenomectomy from 45 patients operated in 1984 before the accident (Group I), and 47 patients from the low contaminated Kiev City (Group II) and 76 from high contaminated area (Group III) operated between 1996 and 1998. Their BPH samples were examined histologically and immunohistochemically. The incidences of prostatic intraepithelial neoplasia (PIN) and high grade PIN (HGPIN) were 15.5 and 11.1% in Group I, 29.8 and 14.9% in Grpoup II, and 35. 5 and 19.7% in Group III. The difference between the incidences of PIN in Group I and III is significant (p<0.02). There was increased apoptosis in areas of PIN in Group II and III as compared to Group I (p<0.001). Since apoptosis has been shown to be associated with ionizing radiation and it is now found to be associated with PIN in patients diagnosed after the Chernobyl nuclear accident, this suggests that long-term low dose internal ionizing radiation potentially may cause prostate cancer.  (+info)

The cost of obesity in Canada. (7/12384)

BACKGROUND: Almost one-third of adult Canadians are at increased risk of disability, disease and premature death because of being obese. In order to allocate limited health care resources rationally, it is necessary to elucidate the economic burden of obesity. OBJECTIVE: To estimate the direct costs related to the treatment of and research into obesity in Canada in 1997. METHODS: The prevalence of obesity (body mass index of 27 or greater) in Canada was determined using data from the National Population Health Survey, 1994-1995. Ten comorbidities of obesity were identified from the medical literature. A population attributable fraction (PAF) was calculated for each comorbidity with data from large cohort studies to determine the extent to which each comorbidity and its management costs were attributable to obesity. The direct cost of each comorbidity was determined using data from the Canadian Institute of Health Information (for direct expenditure categories) and from Health Canada (for the proportion of expenditure category attributable to the comorbidity). This prevalence-based approach identified the direct costs of hospital care, physician services, services of other health professionals, drugs, other health care and health research. For each comorbidity, the cost attributable to obesity was determined by multiplying the PAF by the total direct cost of the comorbidity. The overall impact of obesity was estimated as the sum of the PAF-weighted costs of treating the comorbidities. A sensitivity analysis was completed on both the estimated costs and the PAFs. RESULTS: The total direct cost of obesity in Canada in 1997 was estimated to be over $1.8 billion. This corresponded to 2.4% of the total health care expenditures for all diseases in Canada in 1997. The sensitivity analysis revealed that the total cost could be as high as $3.5 billion or as low as $829.4 million; this corresponded to 4.6% and 1.1% respectively of the total health care expenditures in 1997. When the contributions of the comorbidities to the total cost were considered, the 3 largest contributors were hypertension ($656.6 million), type 2 diabetes mellitus ($423.2 million) and coronary artery disease ($346.0 million). INTERPRETATION: A considerable proportion of health care dollars is devoted to the treatment and management of obesity-related comorbidities in Canada. Further research into the therapeutic benefits and cost-effectiveness of management strategies for obesity is required. It is anticipated that the prevention and treatment of obesity will have major positive effects on the overall cost of health care.  (+info)

Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males. (8/12384)

Several recent studies evaluated a possible effect of the prothrombotic polymorphisms such as 5,10 methylenetetrahydrofolate reductase (MTHFR) nt 677C --> T, factor V (F V) nt 1691G --> A (F V Leiden), and factor II (F II) nt 20210 G --> A on the risk of myocardial infarction. In the present study, we analyzed the effect of these prothrombotic polymorphisms, as well as apolipoprotein (Apo) E4, smoking, hypertension, diabetes mellitus, and hypercholesterolemia, on the risk of myocardial infarction in young males. We conducted a case-control study of 112 young males with first acute myocardial infarction (AMI) before the age of 52 and 187 healthy controls of similar age. The prevalences of heterozygotes for F V G1691A and F II G20210A were not significantly different between cases and controls (6.3% v 6.4% and 5.9% v 3.4% among cases and controls, respectively). In contrast, the prevalence of MTHFR 677T homozygosity and the allele frequency of Apo E4 were significantly higher among patients (24.1% v 10.7% and 9.4% v 5.3% among cases and controls, respectively). Concomitant presence of hypertension, hypercholesterolemia, or diabetes and one or more of the four examined polymorphisms increased the risk by almost ninefold (odds ratio [OR] = 8.66; 95% confidence interval [CI], 3.49 to 21.5) and concomitant smoking by almost 18-fold (OR = 17.6; 95% CI, 6.30 to 48.9). When all atherogenic risk factors were analyzed simultaneously by a logistic model, the combination of prothrombotic and Apo E4 polymorphisms with current smoking increased the risk 25-fold (OR = 24.7; 95% CI, 7.17 to 84.9). The presented data suggest a synergistic effect between atherogenic and thrombogenic risk factors in the pathogenesis of AMI, as was recently found in a similar cohort of women.  (+info)

TY - JOUR. T1 - Autoimmune comorbidities are associated with brain injury in multiple sclerosis. AU - Zivadinov, R.. AU - Raj, B.. AU - Ramanathan, M.. AU - Teter, B.. AU - Durfee, J.. AU - Dwyer, M. G.. AU - Bergsland, N.. AU - Kolb, C.. AU - Hojnacki, D.. AU - Benedict, R. H.. AU - Weinstock-Guttman, B.. PY - 2016/6. Y1 - 2016/6. N2 - BACKGROUND AND PURPOSE: The effect of comorbidities on disease severity in MS has not been extensively characterized. We determined the association of comorbidities with MR imaging disease severity outcomes in MS. MATERIALS AND METHODS: Demographic and clinical history of 9 autoimmune comorbidities confirmed by retrospective chart review and quantitative MR imaging data were obtained in 815 patients with MS. The patients were categorized on the basis of the presence/ absence of total and specific comorbidities. We analyzed the MR imaging findings, adjusting for key covariates and correcting for multiple comparisons. RESULTS: Two hundred forty-one (29.6%) study ...
Health, ...Comorbidities are common among patients with chronic obstructive pulmo... We followed 1664 COPD patients recruited from five pulmonary clinic...The 12 comorbidities with the strongest association with an increased ... We used these 12 comorbidities to develop a new comorbidity risk inde...,Comorbidities,increase,risk,of,mortality,in,COPD,patients,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Two studies observed that a high comorbidity level prior to surgery has a profound impact on short-term revision risk (study II). A novel finding of this thesis was that high comorbidity also affects the long-term revision risk (study II), which has been confirmed by several recent studies. Due to the increasing burden of a variety of comorbidities in THR patients, their association with revision risk and the underlying mechanisms merit further research. To offer some possible explanations for how comorbidity affects revision risk, this thesis focused in more detail on THR patients with diabetes, which has a high and increasing prevalence in both the general population and the THR population. Diabetes increased the risk of revision due to infection, particularly in patients with diabetes for less than 5 years prior to THR, those with complications due to diabetes, and those with cardiovascular comorbidities prior to surgery (study V). These findings were also confirmed recently. However, the ...
The Elixhauser Comorbidity Index was developed using a California-based population dataset of adult, non-maternal inpatients from 438 acute care hospitals in 1992 [32]. The dataset included 1,779,167 patients and 41 comorbidities were listed. No consensus method was employed for making a list of potential candidates for the comorbidity index. Outcomes were defined as length of stay, charges and in-hospital mortality. Statistically unrelated comorbidities to the outcomes were excluded after a series of univariable and multivariable analyses, leading to a final set of 30 comorbidities (Additional file 1: Appendix D) [32]. The authors did not employ item weighting in the phases of development. The Elixhauser Comorbidity Index was developed mainly for use with administrative data. The index has good face validity as well as content validity as the items are mutually exclusive. Feasibility of using the index was not examined in maternal or related research. In the context of maternal health research, ...
We explored multimorbidity patterns and their 6-year evolution in people aged 65 years and older with multimorbidity attended in PHC. The most prevalent chronic diseases, Hypertension, uncomplicated and Lipid disorder, were represented in all clusters in all four groups (i.e., men and women aged 65-79 and ≥80 years). We found 6 clusters per group, 5 of them with a specific pattern related to an organic system: Musculoskeletal, Endocrine-metabolic, Digestive/Digestive-respiratory, Neuropsychiatric and Cardiovascular patterns. We analysed multimorbidity patterns over 6 years and found that they remained quite similar from the beginning to the end of the study period.. We observed a high prevalence of multimorbidity in our population sample, with a higher proportion for women, as in other published studies [5, 8] and described 6 patterns in each study group. In addition, the prevalence of chronic diseases and multimorbidity patterns was similar to previous studies in Catalonia [22] and in other ...
Learn more about how common certain comorbidities are in people with rheumatoid arthritis and why RA patients need health care to address them.
Ranganath VK, Maranian P, Elashoff DA, Woodworth T, Khanna D, Hahn T, Sarkisian C, Kremer JM, Furst DE, Paulus HE. Comorbidities are associated with poorer outcomes in community patients with rheumatoid arthritis.. Rheumatology (Oxford). Oct 1, 2013; 52: 10: 1809-17: PubMed PMID23813577; PubMed Central PMCID: PMC3775293 ...
Objectives - Diabetes frequently coexists with other conditions, resulting in poorer diabetes self-management and quality of life, higher risk for diabetes-related complications and higher health service use compared to those with diabetes only. Few Canadian studies have undertaken a comprehensive, population-level analysis of comorbidity and health service utilization by older adults with diabetes. This study examined comorbidity and its association with a broad range of health services in a cohort of community-dwelling older adults with diabetes in Ontario, Canada.. Methods - We linked multiple administrative databases to create a cohort of 448,736 older adults with diabetes, described their comorbidities and obtained their 1-year use of health services (physician visits, emergency department visits, inpatient hospital admissions, home care use, nursing home admissions). We examined comorbidity patterns by age and gender and estimated the prevalence of 20 comorbid conditions and the most ...
The present study showed that the mean (SD) HL score in our multimorbid primary care patient sample was 2.9 (0.5). In multimorbid patients, a high treatment burden and effects on patients quality of life due to problems with mobility and anxiety/depression were negatively associated with HL. However, our study revealed no association between HL and age. Although several studies have assessed HL, to the best of our knowledge, little is known about which factors are associated with low HL in multimorbid patients in primary care.. The present studys main finding was that the treatment burden facing multimorbid primary care patients was negatively associated with HL. In other words, the lower a multimorbid patients HL, the higher the treatment burden. This is a very interesting finding, and although the β coefficient is small, we believe that this result is clinically relevant and allows us to identify treatment burden as an element to take into account for potentially low literacy in ...
We found significantly higher rates of somatic comorbidity among migrants with PTSD and depression compared with migrants without a diagnosed psychiatric disorder. Adjusted rates were significantly higher in ten out of the fifteen diagnostic categories being especially high for infectious, neurological and pulmonary diseases. Our results further suggest difference in the rates of somatic comorbidity according to region of origin and according to the legal ground of obtaining residency.. Prior to our study, somatic comorbidity in migrants with PTSD and depression have only received scarce attention in the literature [18-21]. Albeit, diagnosis and treatment of somatic comorbidity may help improve management of mental disorders and vice versa. Further, patients with PTSD and depression suffering from somatic comorbidity will require regular treatment and check-up, such as diabetes may need tailored treatment programmes to ensure they are treated according to need. It is therefore important that ...
Background: Patients with HIV infection can present with multiple comorbidities prior to and following the initiation of antiretroviral therapy (ART) including potential risk factors for cardiovascular disease (CVD) and renal impairment and osteoporosis/fracture. Understanding these risk factors can help identify patients at high risk and help optimize HIV treatment. Methods: Adults diagnosed with HIV (ICD-9-CM code: 042.xx, 795.71, V08) in 2002-2013 were selected from MarketScan Commercial, Medicare, and Medicaid databases, which are longitudinal, allowing patients to be observed over multiple years. All patients were continuously enrolled for at least 1 calendar year during 2003-2013. Age and gender entered on the date of the first HIV diagnosis. Comorbid conditions during calendar years 2003-2013 were assessed using diagnosis and procedure codes ...
Figure 1: 7MM, Diagnosed Prevalent Cases of Type 2 Diabetes with Comorbidity, 2016, Men and Women, Ages ≥20 Years. Source: GlobalData.. Type 2 diabetes (T2D) is a chronic disorder of glucose equilibrium that results from the bodys inability to make use of available insulin along with relative insulin deficiency. Among adults only, T2D is expected to make up at least 95% of all diabetes cases.. It is one of the most common non-communicable diseases and is an escalating public health problem globally, with an estimated 415 million people afflicted. Additionally, poorly managed diabetes leads to serious complications such as heart attack, stroke, kidney failure, leg amputation, vision loss, nerve damage, and other serious complications. Figure 1 presents the most common comorbidities in persons with T2D.. GlobalData Epidemiologists forecast that there were 56,060,328 diagnosed prevalent cases of T2D in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan). Additionally, ...
Background: While research in the area of e-mental health has received considerable attention over the last decade, there are still many areas that have not been addressed. One such area is the comorbidity of psychological disorders in a Web-based sample using online assessment and diagnostic tools, and the relationships between comorbidities and psychosocial variables. Objective: We aimed to identify comorbidities of psychological disorders of an online sample using an online diagnostic tool. Based on diagnoses made by an automated online assessment and diagnostic system administered to a large group of online participants, multiple comorbidities (co-occurrences) of 21 psychological disorders for males and females were identified. We examined the relationships between dyadic comorbidities of anxiety and depressive disorders and the psychosocial variables sex, age, suicidal ideation, social support, and quality of life. Methods: An online complex algorithm based on the criteria of the Diagnostic ...
This is a non-randomized open label dose-ranging study of Bendamustine and Rituximab (BR) in patients with previously untreated or relapsed/refractory CLL who have multiple comorbidities (Cumulative Illness Rating Scale [CIRS]≥7) with or without renal insufficiency (estimated creatinine clearance [CrCL] 15-40 mL/min, but not receiving dialysis).. The study will accrue two independent patient cohorts. Both cohorts will follow a standard 3+3 Phase I design. Once the maximum tolerated dose (MTD) is determined, two expansion cohorts will be enrolled. Dose limiting toxicities (DLT) will be assessed during the 1st cycle of treatment.. Patients with CLL who have significant comorbidities (CIRS≥7; at least one category grade 3-4), with or without minor renal dysfunction (CrCL,40 mL/min) will be accrued onto Cohort 1 of the study. At dose level 1, patients will receive bendamustine 45 mg/m2 in combination with rituximab (375 mg/m2 with cycle 1 and 500 mg/m2 with subsequent cycles). If safe, the dose ...
Younger smokers are more likely to be dependent on nicotine and have psychiatric and substance use disorders than their older counterparts, new research shows ...
This is the first report of a projected series regarding the comorbidity of cardiovascular disease (CVD), diabetes and chronic kidney disease (CKD) in Australia. Comorbidity refers to any two or more of these diseases that occur in one person at the same time. The questions to be answered in this report include: 1. How many Australians have comorbidity of CVD, diabetes and CKD? 2. What is the proportion of hospitalisations with these comorbidities? 3. How much do these comorbidities contribute to deaths? 4. What is the magnitude of comorbidity in the context of each individual disease? 5. Are there differences in the distribution of these comorbidities among age groups and sexes ...
Comorbidities are additional chronic conditions that may compromise the health of people living with HIV. Some "comorbid" conditions are more common in people with HIV because they have similar risk factors or because the immune changes associated with HIV infection or the side effects of antiretroviral drugs increase a persons risk of developing them. These comorbidities are now the most common causes of death and disability in people living with HIV. Research on comorbidities aims to understand the underlying links between comorbidities and HIV, and to develop treatment strategies and guidelines to reduce their impact on the lives and well-being of people living with HIV.. ...
Особенности фармакотерапии коморбидных сердечно-сосудистых заболеваний у женщин с постменопаузальным остеопорозом
Data was collected between 2006 and 2010 from adults 18 years of age or older in Boston who have a current diagnosis of alcohol dependence and heavy drinking and/or drug dependence and recent drug use.. Specifically, the following inclusion criteria were met at study entry: (1) Male and female subjects must be 18 years of age or older; (2) Must have a current diagnosis of Alcohol dependence and heavy drinking: Alcohol dependence as determined using the (10-items if none skipped) Composite International Diagnostic Interview Short Form (CIDI-SF) that yields a DSM-IV diagnosis and heavy drinking in the past 30 days, defined as greater than or equal to 4 standard drinks for women, greater than or equal to 5 for men at least twice in the past month, or greater than or equal to 22 drinks per week for men or greater than or equal to 15 drinks per week for women in an average week in the past month and/or Drug dependence and recent drug use: Drug dependence (DD) as determined by using the Composite ...
Accountable Care Organizations, which used to be the wave of the future, are the here and now. As groups of doctors, hospitals and other healthcare providers come together to coordinate care, it is essential they include behavioral health providers in the mix. According to a recent National Comorbidity Survey, 17 percent of the adult population had comorbid mental and medical conditions within a 12-month period. Patients with comorbidities require a comprehensive treatment plan to truly bend the cost curve. For…. ...
The term "comorbidity" refers to the coexistence or presence of multiple diseases or disorders in relation to a primary disease or disorder in a patient [1]. Multimorbidity can be also defined as coexistence of two or more diseases, but no index disease is considered [2]. A comorbidity relationship between two diseases exists whenever they appear simultaneously in a patient more than chance alone. It represents the co-occurrence of diseases or presence of different medical conditions one after another in the same patient [3, 4]. Some diseases or infections can coexist in one person by coincidence, and there is no pathological association among them. However, in most of the cases, multiple diseases (acute or chronic events) occur together in a patient because of the associations among diseases. These associations can be due to direct or indirect causal relationships and the shared risk factors among diseases [5, 6]. For an instance, people with HIV-1 appear to have a markedly higher rate of ...
Background: CVD, AH and DM are common comorbidities in COPD. Their association with the new GOLD 2011 classification has not been evaluated.. Objective:To evaluate the prevalence of CVD, AH and DM in patients admitted to the hospital for COPD exacerbation (AECOPD).. Methods:609 patients admitted for AECOPD were followed-up monthly for one year.. Results:Patients classification according to GOLD 2011 and the prevalence of CVD, AH and DM are shown in Table 1. Comorbid diseases were more common in more severe COPD. Patients without comorbidities had fewer AECOPD in 1 year compared to patients with 1, 2 and 3 comorbidities (0.4±0.5, 1.9±2.5, 3.6±3.3 and 4.6±3.5 respectively, p,0.001) as well as fewer hospitalizations for AECOPD (0.1±0.3, 0.7±1.6, 1.6±1.9 and 2.0±2.6, respectively, p,0.001). Patients in group B with comorbidities had more AECOPD and hospitalizations in 1 year compared to group C (p,0.001). The presence of comorbidities was an independent predictor of AECOPD and ...
Background There has been an increasing prevalence of both depression and chronic medical conditions globally but the relationship between depression and multi-morbidity is not well understood. The...
In this analysis we demonstrate that, despite strict inclusion and exclusion criteria for eligibility to enroll in a clinical trial, there are significant differences in baseline clinical characteristics among study sites according to enrollment volume. Such variations have been previously reported related to regional differences among participants. To our knowledge, this is the first report that shows significant differences in participants baseline clinical characteristics on the basis of the number of participants enrolled by any individual clinical trial site. These differences spanned demographic and clinical characteristics, comorbidity burden, and laboratory parameters. Participants from the trial sites that enrolled fewer individuals had worse health at baseline. The less prevalent dyspnea and rales coupled with lower blood pressure and worse renal function, and higher use of inotropes all suggest that participants enrolled at lower enrolling sites likely represent a proportion of ...
This quick-reference chart names the most common comorbid conditions that come with ADHD, plus symptoms, common treatments, and recommended resources for each.
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We are looking for a PhD student! The PhD fellow will be part of a team working on several projects focused on the immunopathology of tuberculosis and testing drugs and vaccine candidates in several animal models. The PhD student will focus his/her research on understanding how comorbidities are involved in the pathogenesis of tuberculosis while being…
In a recent study to help inform future interventions for patients who have both diabetes and other comorbid conditions, Dr. Elizabeth Magnan et al. examined how 62 chronic conditions individually related to achievement of diabetes care quality goals. The authors found that the 62 conditions varied in their relationships to diabetes care goal achievement, with congestive heart failure, obesity, mental health conditions, and substance use disorders relating to a lack of achievement in at least one measure. ...
Research Hospitalization Volume, DRGs, Quality Outcomes, Top Hospitals & Physicians for DRG 374: DIGESTIVE MALIGNANCY WITH MAJOR COMPLICATION OR COMORBIDITY (MCC)
The validity of analyses testing the etiology of comorbidity between two disorders: a review of family studies Journal Article ...
comorbidity definition: the clear presence of several conditions (or conditions) as well as a primary illness or condition.; the end result of these extra problems or conditions.; The presence of more…
Study of the untoward effects associated with the comorbidity of multiple diseases on brain morphology requires identifying differences across multiple diagnostic groupings. To identify such effects...
Swendsen, Joel, Conway, Kevin P., Degenhardt, Louisa, Dierker, Lisa, Glantz, Meyer, Jin, Robert, Merikangas, Kathleen R., Sampson, Nancy, Kessler, Ronald C. Socio-demographic risk factors for alcohol and drug dependence: The 10-year follow-up of the National Comorbidity Survey ...
Hatlen, Peter; Amundsen, Tore. (2014) Lung cancer - influence of comorbidity on incidence and survival. The Nord-Trøndelag Healt study. 2014. ISBN 978-82-471-4956-0. Doktoravhandlinger ved NTNU (23). ...
Penile discharge, infected-looking glans. A 67-year-old male with multiple comorbidities with penile discharge and pale-appearing glans. It seems that the patient has had multiple catheterizations recently and has history of peripheral vascular disease.
If you have a patient whos been a heavy drinker and heavy smoker (like five 40-ouncers and a couple packs a day) since their teens, and theyre now in their 60s, and they live with family members who are unlikely to stop smoking and drinking just to keep them healthy, and they also live in a food desert and have multiple comorbidities and things generally suck, it is not a dereliction of duty not to suggest that they get their carotid arteries Roto-Rooted in order to restore blood flow to their brain after a minor stroke ...
A list of recent articles highlighting the complexity of psychiatric and systemic illness, both in terms of overlapping clinical presentation and in the degrees to which systemic illness and psychiatric illness affect each other.
Purpose: The aim of this study is to assess the effect of comorbidities on risk of readmission to an intensive care unit (ICU) and the excess hospital mortality associated with ICU readmissions.. Materials and Methods: A cohort study used clinical data from a 22-bed multidisciplinary ICU in a university hospital and comorbidity data from the Western Australian hospital morbidity database.. Results: From 16 926 consecutive ICU admissions between 1987 and 2002, and 654 (3.9%) of these patients were readmitted to ICU readmissions within the same hospitalization. Patients with readmission were older, more likely to be originally admitted from the operating theatre or hospital ward, had a higher Acute Physiology and Chronic Health Evaluation (APACHE)-predicted mortality, and had more comorbidities when compared with patients without readmission. The number of Charlson comorbidities was significantly associated with late readmission (,72 hours) but not early readmission (≤72 hours) in the ...
1. Global perspectives on mental-physical comorbidity Michael R. Von Korff; Part I. An Epidemiological Map of Mental-Physical Comorbidity: 2. The global burden of chronic physical disease Michael R. Von Korff; 3. The global burden of chronic pain Adley Tsang and Sing Lee; 4. World Mental Health Survey methods for studying mental-physical comorbidity Gemma Vilagut, Kathleen Saunders, and Jordi Alonso; 5. The pattern and nature of mental-physical comorbidity: specific or general Oye Gureje; 6. Age patterns in the prevalence of depressive and anxiety disorders by physical comorbidity status Kate M. Scott; Part II. Risk Factors for Mental-Physical Comorbidity: 7. The development of mental-physical comorbidity Kate M. Scott; 8. Childhood adversity, early-onset mental disorders and adult-onset asthma Kate M. Scott; 9. Childhood adversities, mental disorders and heart disease Huibert Burger; 10. Early childhood adversities and later hypertension Dan Stein, Kate M. Scott, and Michael R. Von Korff; 11. ...
TY - JOUR. T1 - Prevalence of Medical and Psychiatric Comorbidities Following Traumatic Brain Injury. AU - Hammond, Flora M.. AU - Corrigan, John D.. AU - Ketchum, Jessica M.. AU - Malec, James F.. AU - Dams-OConnor, Kristen. AU - Hart, Tessa. AU - Novack, Thomas A.. AU - Bogner, Jennifer. AU - Dahdah, Marie N.. AU - Whiteneck, Gale G.. PY - 2019/7/1. Y1 - 2019/7/1. N2 - Objective: To examine the prevalence of selected medical and psychiatric comorbidities that existed prior to or up to 10 years following traumatic brain injury (TBI) requiring acute rehabilitation. Design: Retrospective cohort. Setting: Six TBI Model Systems (TBIMS) centers. Participants: In total, 404 participants in the TBIMS National Database who experienced TBI 10 years prior. Interventions: Not applicable. Main Outcome Measure: Self-reported medical and psychiatric comorbidities and the onset time of each endorsed comorbidity. Results: At 10 years postinjury, the most common comorbidities developing postinjury, in order, ...
Objectives: little is known about the trends of the cardiovascular comorbidities associated with cardiac arrest in the developing countries and how they affect mortality. This was examined in this study in patients hospitalized alive after out of hospital cardiac arrest in a real-world population in a Middle-Eastern Country.. Methods: Retrospective analysis of prospective registry of all patients hospitalized alive after out of hospital cardiac arrest in Qatar from 1991 through 2010 was made. Rates and trends of cardiac comorbidities and in-hospital mortality were examined.. Results: During the 20-years period 801 patients were hospitalized alive after out of hospital cardiac arrest; 577 men and 224 women. In the latter years of the study there was increase in the prevalence of diabetes mellitus and hypertension when compared to patients hospitalized in the earlier years. Associated ischemic heart disease and heart failure were also trending higher. The study also demonstrated an increasing ...
Job: Nissenson et al: CURRENT Diagnosis & Treatment: Nephrology and Hypertension back cover copy --0071447873; 9780071447874)[title]CURRENT Diagnosis & Treatment:Nephrology and Hypertension[authors]Edgar V. Lerma, MDJeffrey S. Berns, MDAllen R. Nissenson, MD[Left column]A complete, yet clinically focused guide to managing the full spectrum of kidney diseases and hypertensionIncisive, ready-to-use management protocols and valuable therapeutic guidelines - from authors who are recognized as the fields foremost authoritiesPresented in the consistent, easy-to-follow CURRENT style[Right column][headline]Accessible, concise, and up-to-date CURRENT Diagnosis & Treatment in Nephrology and Hypertension features: One-of-a-kind clinical overview of all major diseases and disorders, from end-stage renal disease to primary and secondary hypertension A practical, learn-as-you-go approach to diagnosing and treating renal disorders and hypertension that combines disease management techniques with the latest ...
The effect of comorbidities on COPD assessment: a pilot study Ulla Møller Weinreich,1–3 Lars Pilegaard Thomsen,2 Barbara Bielaska,4 Vania Helbo Jensen,5,6 Morten Vuust,4 Stephen Edward Rees2 1Department of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark; 2Respiratory and Critical Care Group (RCARE), Centre for Model-Based Medical Decision Support Systems, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark; 3The Clinical Institute, Aalborg University Hospital, Aalborg, Denmark; 4Department of Radiology, Vendsyssel Hospital, Hjørring, Denmark; 5Department of Radiology, Horsens Regional Hospital, Horsens, Denmark; 6Department of Radiology, Aalborg University Hospital, Aalborg, Denmark Introduction: Patients with chronic obstructive pulmonary disease (COPD) frequently suffer from comorbidities. COPD severity may be evaluated by the Global initiative for chronic ­Obstructive Lung Disease (GOLD) combined risk assessment score
Erratum: The relative effect of Alzheimers disease and related dementias, disability, and comorbidities on cost of care for elderly persons (Journals of Gerontology - Series B Psychological Sciences and Social (September 2001) 56B (S285-S293))
The National Comorbidity Survey: Baseline (NCS-1) was a collaborative epidemiologic investigation designed to study the prevalence and correlates of DSM III-R disorders and patterns and correlates of service utilization for these disorders. The NCS-1 was the first survey to administer a structured psychiatric interview to a nationally representative sample. The survey was carried out in the early 1990s with a household sample of over 8,000 respondents. Subsamples of the original respondents completed the NCS-1 Part II survey and Tobacco Use Supplement. Diagnoses were based on a modified version of the Composite International Diagnostic Interview (the UM-CIDI), which was developed at the University of Michigan for the NCS-1. Drugs covered by this survey include alcohol, tobacco, sedatives, stimulants, tranquilizers, analgesics, inhalants, marijuana/hashish, cocaine, hallucinogens, heroin, nonmedical use of prescription drugs, and polysubstance use. Other items include demographic characteristics,
Results: A total of 400 isolates were obtained (93%E. coli and 7%Klebsiella spp). In 2009, 6% of cultures were ESBL-producing E. coliand 7% in 2010. 37% of patients were men and 81% were aged ≥ 60 years. CI was 2.3 ± 1.8 (high comorbidity: 42.8%). 41.5% of strains were susceptible to amoxicillin-clavulanate, 85.8% to fosfomycin and 15.5% to ciprofloxacin. The total number of ESBL E. coli positive urine cultures during hospital admission was 97 and, compared with 103 controls, risk factors for UTI caused by ESBL- E. coli strains in hospitalised patients were nursing home residence (p , 0.001), diabetes (p = 0.032), recurrent UTI (p = 0.032) and high comorbidity (p = 0.002). In addition, these infections were associated with more symptoms (p , 0.001) and longer admission (p = 0.004).. ...
Information on comorbid conditions is essential in routine clinical practice and also for research purposes. We have designed a simple, self-report questionnaire to obtain comorbidity data in patients with advanced kidney failure, receiving treatment by dialysis. The questionnaire-derived comorbidity score - the CSCS - was significantly predictive of short-term survival in this patient group and may have clinical utility.. We found almost perfect or substantial levels of agreement between the prevalence of self-reported diabetes, heart disease and cancer and the prevalence of these conditions derived from the detailed examination of the patients medical records. The level of agreement for liver disease was moderate. For arthritis, lung disease, cerebrovascular disease and depression the levels of agreement were only fair. Whilst lung disease and cerebrovascular disease were under-reported by patients, arthritis and depression were reported more frequently compared to the medical records. There ...
These data show that both functional outcome at the time of hospital discharge and 1-year mortality rates are associated independently with the number and severity of patients comorbid diseases as reflected in a modified version of the Charlson Index. This analysis specifically extends the usefulness of the Charlson Index as a measure of comorbidity for studies focused on acute ischemic stroke.. There are a variety of parameters that may reflect the validity of a scale. Content validity indicates how well a scale includes domains thought to be relevant to a condition. Convergent validity is demonstrated when scales or items that are thought to measure the same construct have high correlation coefficients. Divergent validity is demonstrated when items or scales thought to measure different constructs have low correlation coefficients. In this case, there is no "gold standard" measure of aggregate comorbidity for comparison, so these types of validity cannot be assessed. The present study does ...
Comorbidity is the rule, not the exception, in bipolar disorder. The most common mental disorders that co-occur with bipolar disorder in community studies include anxiety, substance use, and conduct disorders. Disorders of eating, sexual behavior, attention-deficit/hyperactivity, and impulse control, as well as autism spectrum disorders and Tourettes disorder, co-occur with bipolar disorder in clinical samples. The most common general medical comorbidities are migraine, thyroid illness, obesity, type II diabetes, and cardiovascular disease. Bipolarity is a marker for comorbidity, and comorbid disorders, especially multiple conditions occurring when a patient is young, may be a marker for bipolarity. Relatively few controlled clinical studies have examined the treatment of bipolar disorder in the context of comorbid conditions (i.e., complicated or comorbid bipolar disorder). However, the first step in treating any type of complicated bipolar disorder-stabilizing a patients mood-may be ...
Many breast cancer survivors have coexistent chronic diseases or comorbidities at the time of their cancer diagnosis. The purpose of the study was to evaluate the association of comorbidities on breast cancer survivors quality of life. A prospective design was used to recruit 140 women before cancer surgery, 134 women completed the study. Comorbidities were assessed using self-report and verified by medical record review and the Charlson Comorbidity Index (CCI) before and 12-month after cancer surgery. Quality of life was evaluated using Short-Form Health Survey (SF-36 v2). Descriptive statistics, chi-square tests, t-tests, Fishers exact test, and correlations were performed for data analysis. A total of 28 comorbidities were identified. Among the 134 patients, 73.8% had at least one of the comorbidities, 54.7% had 2-4, and only 7.4% had 5-8. Comorbidities did not change at 12 months after surgery. Numbers of comorbidities by patients self-report and weighted categorization of comorbidities by CCI
How do comorbid psychiatric disorders affect the treatment of OCD? Learn about adjustments in psychotherapy and pharmacotherapy to optimize treatment for your patients with OCD and comorbid depression, bipolar disorder, schizophrenia, or eating disorders.
Our study showed that comorbidities, such as heart failure, diabetes, renal disease or metastatic tumours had a major impact on outcomes in patients hospitalised with ACS and confirmed previous studies that chronic comorbidities are frequently encountered in patients admitted for ACS in daily clinical practice.. The baseline characteristics of the ACS patients differed significantly between the CCI groups and in particular between those with no comorbidities (CCI0) and those patients with CCI1-CCI≥3, as clearly demonstrated by the risk factors hypertension, dyslipidemia and obesity. However, the proportion of current smokers was highest in the CCI0 group but steadily decreased the higher the weighted CCI. The higher the CCI, the longer the delay between symptom onset and admission, symptoms were less typical, there was a higher degree of haemodynamic instability (higher Killip class) and more frequent NSTEMI/UA compared with the patients with lower rates of comorbidities. ACS patients with ...
TY - THES. T1 - The long-term impact of rheumatoid arthritis and comorbidity on functioning and mortality. AU - van den Hoek, Joëlle. PY - 2017/12/15. Y1 - 2017/12/15. M3 - Research external, graduation external. ER - ...
Methods: We conducted a nationwide population-based cohort study. Using the Danish National Registry of Patients, covering all Danish hospitals, we identified all 219,354 patients with a first-time hospitalization for stroke during 1994-2011. We computed standardized 30-day, 1-year, and 5-year mortality by sex. Comorbidity categories were defined by Charlson Comorbidity Index scores of 0 (none), 1 (moderate), 2 (severe), and 3 or more (very severe). Calendar periods of diagnosis (1994-1998, 1999-2003, 2004-2008, and 2009-2011) and comorbidity categories were compared by means of mortality rate ratios based on Cox regression. Read More. ...
We discuss comorbidity, continuity, and discontinuity of anxiety-related disorders from the perspective of a two-dimensional neuropsychology of fear (threat avoidance) and anxiety (threat approach). Pharmacological dissection of the "neurotic" disorders justifies both a categorical division between fear and anxiety and a subdivision of each mapped to a hierarchy of neural modules that process different immediacies of threat. It is critical that each module can generate normal responses, symptoms of another syndrome, or syndromal responses. We discuss the resultant possibilities for comorbid dysfunction of these modules both with each other and with some disorders not usually classified as anxiety related. The simplest case is symptomatic fear/anxiety comorbidity, where dysfunction in one module results in excess activity in a second, otherwise normal, module to generate symptoms and apparent comorbidity. More complex is syndromal fear/anxiety comorbidity, where more than one module is ...
Comorbidity is an area of increasing interest in MS and evidence has suggested comorbidity is associated with diagnostic delays, misinterpretation of relapses, disability progression, health-related quality of life, and progression of lesion burden on magnetic resonance imaging (MRI). In chronic diseases, it has been shown that comorbidities can affect multiple aspects of treatment.. The aim of this resource guide is to help clinicians recognize and differentiate comorbidities from MS symptoms, understand the impact of comorbidities on individuals, make decisions about treatment in the setting of comorbidities, and manage comorbidities in collaboration with other health care professionals. The general prevalence and impact of comorbidities in MS will be reviewed, with the greatest focus on psychiatric, vascular/metabolic, and autoimmune comorbidities. Conditions defined as comorbidities in this document are those that are chronic in nature and that originate by a mechanism that is distinct from ...
Results Mean aPWV was 10.3 (SD 2.6) m/s, AIx 27 (10)%, brachial BP 144/82 (18/11) mmHg, central BP 131/82 (18/11) mmHg, CIMT 0.86 (0.4) mm.. BODE correlated with aPWV (p , 0.0001) and this was maintained when adjusted for study site, age, supine heart rate (HR) mean arterial pressure (MAP), years smoked and cardiovascular comorbidities (MI, stroke, diabetes, peripheral vascular disease), p , 0.0001. BODE was also associated with AIx when adjusted for site, age, seated HR and MAP, years smoked and cardiovascular comorbidities, p , 0.01. The constituent variables of BODE did not have the same significant association with both aPWV and AIx, Table 1. ...
Background & Objective: Type 2 diabetes is a complex disease characterized by multiple comorbidities. Depression is one of the most common comorbidities in individuals with diabetes with prevalence rates reaching 30%. Depression complicates diabetes treatment, portends worse outcomes and increases health care costs. One novel approach to managing diabetes with co-morbid depression is a collaborative primary care model involving a multidisciplinary health care team guiding patient-centered care. This model has been tested in the US and showed a significant reduction of depressive symptoms, improved diabetes care and patient-reported outcomes, and saved money. Our aim is to evaluate the implementation of this collaborative care model for type 2 diabetes and comorbid depression within the non-metro Primary Care Network (PCN) setting in Canada.. Intervention: The intervention involves three phases: (1) improving depressive symptoms, (2) improving blood sugar, blood pressure and cholesterol, and (3) ...
Introduction: The impact of comorbidity on overall survival among older women diagnosed with breast cancer has been studied extensively. However, less is known about its impact on overall survival among women diagnosed with breast cancer before age 65 years.. Methods: We followed 4516 (1605 black, 2911 white) women ages 35 to 64 years when diagnosed with incident invasive breast cancer between 1994 and 1998. The pre-diagnosis history of 11 comorbid conditions and whether they had been treated were collected shortly after breast cancer diagnosis. Multivariate Cox regression models were used to examine the impact of these comorbidities on overall survival.. Results: During a median of 8.2 years follow-up, 1052 (524 black, 528 white) women died. The prevalence of comorbidities diagnosed before breast cancer was higher among black women than among white women (61.3% vs. 44.7%). Compared to women without any comorbidities, women were at increased risk of death if they had any treated comorbidity ...
The lifetime prevalence of DSM-III-R alcohol abuse and alcohol dependence and associated patterns of psychiatric comorbidity in the Ontario population aged 15-64 years are estimated from a survey ofa representative household sample using the University of Michigan Composite International Diagnostic Interview UM-CIDI. More than half 55% of all...
Background: Atrial fibrillation (AF) is more frequent in elderly pts and those with underlying cardiac and other comorbidities. The multicenter ENGAGE AF-TIMI 48 trial compared efficacy and safety of edoxaban vs warfarin in 21105 pts with AF over a mean follow up of 2.8 yrs. We hypothesized that despite more adverse events in pts with mod-high comorbidity, the benefits of edoxaban over warfarin would be similar to that seen in pts with less comorbidity.. Methods: Pts were classified using the Charlson Comorbidity Index (CCI) as low comorbidity (CCI ,4, n=15860 pts) or mod-high comorbidity (CCI ≥4, n=5245 pts). Outcomes included study drug discontinuation, serious (non-bleeding) adverse events (SAEs), hepatic events, new neoplasms, and all cause death.. Results: Pts with CCI ,4 were more likely male, with higher BMI, enrolled in NA, and received fewer cardiac co-medications. They had higher CHA2DS2VASc (mean 5.2 vs 4.0) and HASBLED (2.7 vs 2.4) scores, and higher median TTR with warfarin (69 vs ...
BY: Leigh Brosof DATE: 4 August 2017 Comorbidity is when two or more psychiatric disorders co-occur (or happen together) in the same individual, either at the same time or at different times (lifetime comorbidity).1 In individuals with eating disorders, comorbidity is common: with up to 97% of individuals with eating disorders also having another psychiatric…
Gron KL., Ornbjerg LM., Hetland ML., Aslam F., Khan N., Jacobs JWG., Henrohn D., Rasker H., Kauppi M., Lang HC., Mota L., Aggarwal A., Hisashi Y., Badsha H., Gossec L., Cutolo M., Ferraccioli G., Lee EB., Direskeneli H., Taylor PC., Huisman M., Alten R., Pohl C., Oyoo O., Stropuviene S., Drosos AA., Kerzberg E., Ancuta C., Mofti A., Bergman M., Detert J., Selim ZI., Abda EA., Rexhepi B., Sokka T ...
Assessment of Correlations among Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL) and Cumulative Illness Rating Index (CI) Scores in the Elderly Patients with Femur Fractures: A Prospective Study
This survey identified key areas of improvement in terms of knowledge and development of specific skills for epileptologists regarding management of the psychiatric comorbidities of epilepsy. For the first time, psychiatrists were involved in the process and it was possible to identify specific needs for adult and child neurologists treating patients with epilepsy.. Epileptologists are keen to improve their clinical skills and screening during routine clinical practice seems to be the priority. Most adult neurologists feel inadequate or not skilled enough when dealing with patients with epilepsy and ASD, ADHD, or IDs in general. Child neurologists are historically better trained in these conditions and thus, usually more adept in their management. A prospective community-based study of children and adolescents with active epilepsy showed that up to 40% of patients have IDs, one third have ADHD, and around 20% have ASD (Reilly et al., 2014). In addition, a community-based survey of more than ...
TY - JOUR. T1 - An in-depth look into PTSD-depression comorbidity. T2 - Journal of Affective Disorders. AU - Horesh,Danny. AU - Lowe,Sarah R.. AU - Galea,Sandro. AU - Aiello,Allison E.. AU - Uddin,Monica. AU - Koenen,Karestan C.. PY - 2017/1/15. Y1 - 2017/1/15. N2 - Background Although PTSD-major depressive disorder (MDD) co-morbidity is well-established, the vast majority of studies have examined comorbidity at the level of PTSD total severity, rather than at the level of specific PTSD symptom clusters. This study aimed to examine the long-term associations between MDD and PTSD symptom clusters (intrusion, avoidance, hyperarousal), and the moderating role of gender in these associations. Methods 942 residents of urban Detroit neighborhoods were interviewed at 3 waves, 1 year apart. At each wave, they were assessed for PTSD, depression, trauma exposure, and stressful life events. Results At all waves, hyperarousal was the PTSD cluster most strongly correlated with MDD. For the full sample, a ...
There is a very high comorbidity of serious depression in fibromyalgia patients, points out Michael Golinkoff, PhD, MBA, chief clinical officer at Aetna Behavioral Health. He says that Aetna routinely screens for depression in these patients.. "Even with patients who do not meet diagnostic criteria for depression, we often find that there are many psychological symptoms present," says Golinkoff. As fibromyalgia is "very stressing, very debilitating, addressing this suffering is an important part of the treatment plan." Thus it is critical to refer patients as appropriate to psychotherapy and other associated treatments, Golinkoff says.. Golinkoff recommends the meta-analysis of psychological treatments for fibromyalgia by Julia A. Glombiewski et al in the journal Pain (2010; 151: 280-295), both the text and the incorporated references. This study found cognitive-behavioral therapy was associated with the greatest effect sizes and reports that "meta-analytic integration resulted in a significant ...
The patients encountered in general practice, particularly those with multimorbidity, present a combination of interacting problems, which make adherence to clinical practice guidelines (CPG) and clinical decision making very difficult when recommendations cumulate across several conditions [1]. Nine out of ten patients seen in general practice have more than one chronic condition [2, 3]. In 2005, Cynthia Boyd and colleagues illustrated the limitations of the current type of CPGs. They aggregated recommendations from relevant clinical guidelines for a hypothetical case of a 79-year-old multimorbid woman and ended up with 12 medications, prescribed in 19 partial doses, and a complicated nonpharmacological regimen [4]. This hypothetical case shows that the current way of designing CPGs is even associated with undesirable effects for persons with several comorbidities, and that adverse interactions between drugs and diseases, conflicting management strategies, and polypharmacy might result [5]. ...
The study by Weinberger and colleagues is a well-designed randomized study of a complex intervention for patients with type 2 diabetes mellitus. Preemptive phone management by trained nurses who monitored patient symptoms, advised about dietary modifications, and facilitated access to physician care when appropriate improved glycemic control but did not affect health-related quality of life. There are 3 noteworthy aspects of this study. First, the generalizability is limited. The study included men who were military veterans, the intervention was open-ended (nurses were free to provide various medical services), the patients had high comorbidity (patients took 5 to 6 medications at baseline), and the improved access to care may have allowed more medication adjustments. Second, the effect on GHb was modest. No effect on quality of life resulted. Finally, the increased resource allocation per patient was trivial (12 min/mo); the outcome improvement came at little cost. Substantial improvement in ...
This synthesis examines the evidence on physical and mental comorbidity including its prevalence, origins and models for effective treatment.
RESULTS: Associations between comorbidities and all outcomes were comparable across the three scores. All scores added predictive ability to models including age, gender, race, current smoking status, pack-years smoked and FEV1 (p,0.001 for all comparisons). Area under the curve (AUC) was similar between all three scores across outcomes: SGRQ (range 0·7624-0·7676), MMRC (0·7590-0·7644), 6MWD (0·7531-0·7560) and exacerbation risk (0·6831-0·6919). Because of similar performance, the comorbidity count was used for external validation. In the SPIROMICS cohort, the comorbidity count performed well to predict SGRQ (AUC 0·7891), MMRC (AUC 0·7611), 6MWD (AUC 0·7086), and exacerbation risk (AUC 0·7341 ...
Introduction This concept identifies and briefly describes the measures of comorbidity investigated in the Cancer Data Linkage in Manitoba: Expanding the Infrastructure for Research deliverable by Lix et al. (2016). Some of these measures have been used extensively in MCHP research over time, and some are used for the first time in this research. The concept also provides links to more detailed information where available, as well as the relevant section in Lix et al. (2016) that describes the methodology for developing these measures of comorbidity ...
Comorbidities are the presence of one or more additional disorders or diseases co-occurring with a primary disease or disorder. The purpose of this study is to identify diseases that co-occur with HIV/AIDS and analyze the gender differences. Data was
The most common extrapulmonary problems in chronic obstructive pulmonary disease (COPD) patients are cardiovascular comorbidities, muscle weakness and dysfunction [1-3]. Indeed, the reduced peripheral muscle mass and strength increase patients symptoms during effort (fatigue and or dyspnoea) and progressively lead to disability. Furthermore, both lower and upper limb dysfunction has been shown to independently predict the long-term prognosis of COPD patients [2].. The use of arms is involved in many daily domestic tasks and activities. To date, it has been shown that daily arm activities needing elevation above the shoulders may interfere with regular breathing and are associated with dynamic hyperinflation in COPD patients [4]. The research by Meijer et al. [5], published in this issue of the European Respiratory Journal, investigated whether, and in which proportion of muscle effort, arm activities during daily life are different in COPD patients compared with matched healthy individuals. ...
Methods: We estimated (1) the association between depressive symptoms and physical diseases (N = 14,348), (2) the association between gambling and physical diseases (N = 11,385), and (3) the association of sensory responsiveness with somatic symptoms and illness anxiety (N = 205). Logistic regression analyses were conducted to estimate the associations in studies (1) and (2). To estimate the associations in study (3) we conducted a linear multiple regression model. We controlled for potential confounders in all three studies ...
Results 220 out of 592 pts (37.2%) had PsA and 372 out of 592 pts (62.8%) had PsO alone. PsA pts were older then PsO pts - 53.3±0.9 and 46.9±0.9 (p,0.001). In PsA pts CVD coding as I 00 - I 99 were found in significantly more cases than in PsO pts - in 155 out of 220 pts (70.5%)/in 200 out of 372 pts (53.5%) accordingly (p,0.05). In PsA pts AH coding as I 10 - I 15 was found in significantly more cases than in PsO pts - in 138 out of 220 pts (62.7%) and in 178 out of 372 pts (47.9%) accordingly (p,0.001). In PsA pts CVA coding as I 65 - I 66 found significantly often than in PsO pts - in 48 out of 220 pts (22%) and in 57 out of 372 pts (15.3%) accordingly (p,0.05). CHD and Atherosclerosis coding as I 70 were registered significantly often in PsA pts compared to PsO pts - in 40 out of 220 pts (18%) and in 35 out of 372 pts (9.3%) accordingly (p,0.001). ...
This article goes over how to diagnosis and assess co-occuring illnesses as well as the basics of comorbidity. If you have andy questions, call us today.
Bipolar disorder and substance abuse commonly co-occur. In fact, as many as 50% of individuals with bipolar disorder have been found to have a lifetime history of substance abuse or dependence. This article discusses the very important comorbidity of bipolar disorder as it is complicated by substanc …
Those who have comorbid conditions see themselves as much more disabled than those with a single substance use or psychiatric disorder; hence their over-representation in health services. However, as the preceding chapters have illustrated, they are usually in treatment for a single disorder, and the services are not enabled to tackle comorbidity. A frequent message throughout has been that comorbidity is common, yet insufficient research and funding have been directed towards explicating and alleviating the serious problems associated with comorbidity. A telling figure is that presented in the introductory chapter, where it was highlighted that the percentage of the health dollar allocated to mental health services in Australia is currently 5% while the burden of disease due to the mental disorders is rated world-wide at 20%. Add to this the fact that this funding is allocated in general to treatment services for single disorders, with scant regard for individuals suffering comorbid conditions, ...
Prostate Cancer Most common non cutaneous malignancy in men Second leading cancer killer of men Prostate Breast 180,400 cases/yr 182,000 cases/yr 36% of new ca cases 32% of new ca cases 40,400 deaths 46,000 deaths 1/6 chance of dvlp. 1/8 chance of dvlp. Hormone dependence hormone dependence
The most practical, up-to-date, well-referenced guide to the diagnosis and treatment of the medical problems of children - from birth to adolescence · Organized by general topics and by organ systems · Provides concise, evidence-based infor
Data were collected on women diagnosed and treated for ovarian cancer between 2004 and 2009 (pre-ACA; 35,842 patients) and between 2011 and 2014 (post-ACA; 37,145 patients). Stage at diagnosis and time to treatment were assessed for women between the ages of 21 and 64 years and compared with a group of women aged 65 and older (controls, since they had access to Medicare and were more likely to be insured pre- and post-ACA).. Difference-in-differences analysis was performed, using logistical regression to adjust for confounding factors such as race, rural location, income level, education level, Charlson comorbidity score, distance traveled for care, Census region, and care at an academic center. Changes over time were compared between the two groups.. Over time, younger women had a 1.7% gain in early-stage diagnosis (stage I or II) compared with older women. A 1.6% improvement was found for younger women being treated within 30 days of diagnosis compared with women aged 65 and over. Publicly ...
During the last years there has been a growing interest in the genetics of psychiatric disorders, leading to a concomitant increase in the number of publications that report these studies [2]. However, there is still limited understanding on the celular and molecular mechanisms leading to psychiatric diseases, which has limited the application of this wealth of data in the clinical practice. This situation also applies to psychiatric comorbidities. Some of the factors that explain the current situation is the heterogeneity of the information about psychiatric disorders and its fragmentation into knowledge silos, and the lack of resources that collect these wealth of data, integrate them, and supply the information in an intuitive, open access manner to the community. PsyGeNET has been developed to fill this gap ...
غريب يسعى الى أن يكون ممن قال فيهم الرسول صلى الله عليه وسلم: (طوبى للغرباء ...
غريب يسعى الى أن يكون ممن قال فيهم الرسول صلى الله عليه وسلم: (طوبى للغرباء ...
Calculating Measures of Comorbidity Using Administrative Data. Vicki Stagg Statistical Programmer Department of Community Health Sciences Dr. Robert Hilsden Associate Professor Departments of Medicine and Community Health Sciences Dr. Hude Quan Associate Professor Slideshow 539418 by...
Multimorbidity frequency was high. At least 4 in every 5 major adults had ≥2 morbidities and 3 in every 5 had ≥3 morbidities, thus confirming the importance of multimorbidity as a frequent problem in older adults. The elevated number of dyads (n = 22) with prevalence ≥10 % and triads (n = 35) with prevalence ≥5 % highlights implications for the adequate management of health problems in the same individual, with HBP being the problem most often associated with other morbidities.. The percentage of multimorbidity found is consistent with the range of prevalence encountered in two systematic reviews [25, 26] and recent studies [27, 28]. When considering only population-based studies, the frequency found in our analysis was at least 10 percentage points higher with regard to the occurrence of ≥2 morbidities [25]. The comparability of multimorbidity studies is hampered owing to methodological differences, mainly related to the number of conditions included and the instruments used to ...
Object of anesthetic command the worthy consider- ations are: i) MRI cover standards ii) Monitoring the patient iii) Anesthetic directing 1) MRI sanctuary: MRI cover precautions discussed above should be strictly implemented in the MRI escort and iMRI operating allowance Invasive monitoring of systemic arterial pressure should be considered in patients with skull underpinning tumors, especially if intracranial HTN, sig- nificant pump condition, or other underlying comorbidities are the hour Smoking gun in buttress of basing a nursing center on nursing theory: the Denver nursing reckon in gentle caring Uncountable agents may equip some degree of neuroprotection in contrasting studies (mostly in rodents or in vitro) under varying conditions, but there is a paucity of understanding clinical text to guide anesthetic variety in neurologically unguarded patients cheap vardenafil 10mg fast delivery. The industries of piece file acquire toxicology laboratories and researchers in an conjectural mise en ...
DISCLAIMER: This is only an Annie system; cant say it will work for anyone else. I have gone from 240 lbs to 134 lbs (as of this morning). And all my comorbidities are gone, my health is way better than since I was in my 40s, and life is good again. Hope it helps someone else or at least makes you laugh this morning! Without this community, I would not have come so far on the journey! ---------------------------TWO YEARS OUT FROM SLEEVE: Annie Green Before surgery: 240 lbs, 17
Research; Causes and patterns of. Causes and patterns of readmissions in patients with common comorbidities: retrospective cohort study. Evidence suggests that the picture has not changed much since 2011. A 2015 study of federal court employment discrimination litigation by Theodore Eisenberg found.. Dec 22, 2014 · Commercial DNA Testing May Cause Harm, Scientific Studies Show (if You Read Through to the Study Limitations at the End). Learn why the Common Core is important for your child. What parents should know; Myths vs. facts. Correspondence or distance learning courses; Independent study; Internships; Courses not providing credit toward graduation at the offering institution; Courses meeting long hours over a few days; Courses lasting less than 3 weeks; Courses that overlap a CUA session for which the student is enrolled; Study abroad.. CCSS.ELA-Literacy.L.11-12.1.a Apply the understanding that usage is a matter of convention, can change over time, and is sometimes contested.. Several ...
Y weight, ratio of underlying illness and comorbidity to PD patients. Because the risk of NODM was drastically larger in propensity score matched HD sufferers,
Consistent with previous reports that respiratory complications appear to be the most common comorbidity in young subjects with CP,7,10 ∼45% of our study population showed a high exacerbation rate (≥ 2 episodes/y). A relevant proportion of the subjects being studied (22/31, 71%) required, in addition, admission to acute care hospitals due to respiratory disorders during the year before the study. Finding a high hospitalization rate among subjects with CP, Young et al27 likewise reported that the children and young adults they were studying were admitted to acute care hospitals 7 times more often than age-matched peers. Mahon and Kibirige11 emphasized the importance of upper- and/or lower-respiratory-tract infections, which accounted in their study for up to 42% of hospital admissions.. The consequences of respiratory complications in patients with CP in terms of health status, life expectancy, and quality of life and the need for frequent, costly hospitalizations have made identifying ...
6,505 of 9142 patients with registry confirmed breast cancer were coded as primary disease with 0-IIIA stage tumors and were included for study. Approximately 90% received guideline concordant loco-regional treatment; however this outcome varied by age group as 92.9% of women , 65 years and 85.2% ≥ 65 years received standard care (p ,0.0001). Characteristics which best discriminated receipt of guideline concordant care in receiver operating curve (ROC) analyses (C-value) were receipt of BCS versus mastectomy (C = 0.70), patient age (C=0.62), greater tumor stage (C= 0.60), public insurance (C= 0.58) and presence of at least mild comorbidity (C = 0.55). RT following BCS was the most omitted treatment component causing non-concordance in the study population. In multivariable regression, effects of treatment facility, DCIS, race, and comorbidity on non-concordant care differed by age group ...
To our knowledge this is the first study to evaluate the safety of physical exercise in PR programs in patients with COPD. Although the sample size of our study was small, we observed a low incidence of complications during PR.. The most severe complications were cardiovascular and may be frequent since patients with severe COPD have usually been heavy smokers, and preexisting cardiovascular comorbidity is a normal finding and may interfere with PR programs. Our sample included patients with severe COPD with a mean age of 72 years and an elevated percentage of cardiac comorbidity, hypertension and diabetes. It is therefore important to first evaluate cardiac risk in patients with COPD who are prescribed physical exercise in a PR program by performing ergospirometry to determine the origin of limitation related to exercise, in particular in those patients at highest risk.3. The major complications observed were of cardiac origin but were not life threatening. The incidence of complications such ...
I currently work on a med/surg type ICU and have been there for almost a year. It seems recommendations for ICU experience always mention seeking out level 1 trauma centers and I work at a level 2. My unit sees a lot of vents, post surgical pts, GI bleed, ischemic strokes, DKA, severe sepsis, pts with multiple comorbidities, etc. I have not yet had a chance to participate in a code (we maybe have | 1 per week on the whole unit), no opportunity to work with IABPs, Swans, CRRT, or monitoring
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FRACALANZA, Katie A.; MCCABE, Randi E.; TAYLOR, Valerie H. and ANTONY, Martin M.. Bipolar Disorder Comorbidity in Anxiety Disorders: Relationship to demographic profile, symptom severity, and functional impairment. Eur. J. Psychiat. [online]. 2011, vol.25, n.4, pp.223-233. ISSN 0213-6163. http://dx.doi.org/10.4321/S0213-61632011000400005.. Background and Objectives: High rates of comorbidity between anxiety disorders and bipolar disorder (BD) have been reported. Studies on the impact of BD comorbidity in individuals with a principal anxiety disorder have been limited. Methods: Individuals (N = 186) seeking anxiety disorder treatment completed questionnaires and a diagnostic interview. Anxious individuals with comorbid BD were compared to anxious individuals with comorbid depression, and individuals with an anxiety disorder only. Results: Anxious individuals with BD were more likely to report being single, separated or divorced, and to present with greater substance abuse and comorbidity than ...
Dual Diagnosis and Comorbidity. Are you concerned that you, or someone you care about, may be suffering from dual diagnosis or co-existing mental health concerns & addiction issues?. What is Dual Diagnosis or Cormorbidity?. Comorbidity is the medical term used to describe the presence of two (or more) diseases in the same person at one time. Dual diagnosis is a commonly used term meaning that a person has co-existing or co-ocurring mental health and substance use disorders or problems.. Often when a person is struggling with addiction issues there may be a co-occuring mood disorder such as depression that has fueled the development of, or exacerbated, the substance use issues, or vice versa. This results in people having problems related to both their substance use issues and their mental illness.. Both clinical practice and research have established that the high prevalence of coexisting mental illness and substance use disorders is a growing concern in the mental health field in Australia and ...
Objectives:The aims of this study were to estimate the frequency and course of substances use disorders in Latino patients with schizophrenia and to ascertain risk factors associated with substance use disorders in this population. Method: We studied 518 subjects with schizophrenia recruited for a genetic study from the Southwest United States, Mexico, and Central America (Costa Rica and Guatemala). Subjects were assessed using structured interviews and a best estimate consensus process. Logistic regression, χ 2 , ttest, Fishers exact test, and Yates correction, as appropriate, were performed to assess the sociodemographic variables associated with dual diagnosis. We defined substance use disorder as either alcohol or substance abuse or dependence. Results: Out of 518 patients with schizophrenia, 121 (23.4%) had substance use disorders. Comorbid substance use disorders were associated with male gender, residence in the United States, immigration of Mexican men to the United States, history of ...
New Rochelle, NY - Senator Andrea Stewart-Cousins joined members of the Harris Project, a group committed to raising awareness about co-occurring disorders, and students at New Rochelle High School as part of Co-Occurring Disorders Awareness Day. Co-occurring disorders are described as the presence of both a mental health and a substance-use disorder.
Find Dual Diagnosis Treatment Centers in Hermosa Beach, Los Angeles County, California, get help from Hermosa Beach Dual Diagnosis Rehab for Dual Diagnosis Treatment in Hermosa Beach, get help with Co-Occurring Disorders in Hermosa Beach.
Borderline personality disorder often occurs with other illnesses. This is called co-morbidity or having co-occurring disorders. This can make it hard to diagnose, especially if symptoms of other illnesses overlap with the BPD symptoms.. According to the NIMH-funded National Comorbidity Survey Replication-the largest national study to date of mental disorders in U.S. adults-about 85 percent of people with BPD also suffer from another mental illness.5 Over half the BPD population suffers from Major Depressive Disorder. When depression and BPD co-occur, the depression often does not lift (even with medication), until the borderline personality disorder symptoms improve.. Women with BPD are more likely to have co-occurring disorders such as major depression, anxiety disorders, substance abuse or eating disorders. In men, BPD is more likely to accompany disorders such as substance abuse or antisocial personality disorder.. Most co-morbidities are listed below, followed by the estimated percent of ...
STEIN, Dan J et al. Perpetration of gross human rights violations in South Africa: association with psychiatric disorders. SAMJ, S. Afr. med. j. [online]. 2009, vol.99, n.5, pp.390-395. ISSN 2078-5135.. BACKGROUND: A nationally representative study of psychiatric disorders in South Africa provided an opportunity to study the association between perpetration of human rights violations (HRVs) during apartheid and psychiatric disorder. Prior work has suggested an association between perpetration and post-traumatic stress disorder (PTSD), but this remains controversial. METHODS: Subjects reported on their perpetration of human rights violations, purposeful injury, accidental injury and domestic violence. Lifetime and 12-month prevalence of DSM-IV (Diagnostic and Statistical Manual, 4th edition) disorders were assessed with Version 3.0 of the World Health Organization Composite International Diagnostic Interview (CIDI 3.0). Socio-demographic characteristics of these groups were calculated. Odds ...
Purpose: To investigate the clinical management and outcome of patients with muscle-invasive bladder cancer with clinical lymph node involvement, using longitudinal nationwide population-based data.. Methods: In the Bladder Cancer Data Base Sweden (BladderBaSe), treatment and survival in patients with urinary bladder cancer clinical stage T2-T4 N + M0 diagnosed between 1997 and 2014 was investigated. Patients´ characteristics were studied in relation to TNM classification, curative or palliative treatment, cancer-specific (CSS) and overall survival (OS). Age at diagnosis was categorised as ≤60, 61-70, 71-80 and ,80 years, and time periods were stratified as follows: 1997-2001, 2002-2005, 2006-2010 and 2011-2014.. Results: There were 786 patients (72% males) with a median age of 71 years (interquartile range = 64-79 years). The proportion of patients with high comorbidity increased over time. Despite similar low comorbidity, curative treatment was given to 44% and to 70% of those in older (,70 ...
Comorbidity[edit]. GAD and depression[edit]. In the National Comorbidity Survey (2005), 58 percent of patients diagnosed with ... Comorbidity and treatment[edit]. A study on comorbidity of GAD and other depressive disorders has shown that treatment is not ... and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication". Archives of General Psychiatry. ... Impact of Comorbidity on Psychotherapy Outcome and Impact of Psychotherapy on Comorbidity Diagnoses". Behavior Therapy. 41 (1 ...
Comorbidity[edit]. Anhedonia is present in several forms of psychopathology.[40] Depression[edit]. Social anhedonia is observed ... which may be due to the high comorbidity with depression.[2] ...
Comorbidities[edit]. Patient with other serious medical conditions are at greater chance for negative side effects after ... Examples of comorbidities include heart failure, COPD, neuromuscular disease. Use the ASA Classification to predict a patient's ... However, there are some things to consider when administering PSA, such as the patient's age, medical comorbidities, and ... like with older age and other medical comorbidities, but that if there is a complication, it will be hard for the physician to ...
... is a common comorbidity with autism spectrum disorders[59][60][61][62][63][64][65] and is now ... Other comorbidities[edit]. Various conditions can involve SPD, such as obsessive compulsive disorder,[73] schizophrenia,[74][75 ...
Comorbidity[edit]. ASPD commonly coexists with the following conditions:[68] *Anxiety disorders ...
Online comorbidity scoring tools. Further reading[edit]. *Comorbidity: Addiction and Other Mental Illnesses. Rockville, MD: U.S ... Comorbidity-polypharmacy score (CPS)[edit]. The comorbidity-polypharmacy score (CPS) is a simple measure that consists of the ... Elixhauser comorbidity measure[edit]. The Elixhauser comorbidity measure was developed using administrative data from a ... The comorbidities were not simplified as an index because each comorbidity affected outcomes (length of hospital stay, hospital ...
Comorbidity[edit]. Schizophrenia[edit]. Main article: Schizophrenia. Schizophrenia is a mental disorder distinguished by a loss ...
Comorbidity[edit]. The determination of the cause of ARFID has been difficult due to the lack of diagnostic criteria and ...
Co-morbidity[edit]. A large percentage of children that suffer from PEM also have other co-morbid conditions. The most common ... These co-morbidities tax already malnourished children and may prolong hospital stays initially for PEM and may increase the ... The general explanation of increased infectious comorbidity in malnourished people is that (1) the immune system is what ... co-morbidities are diarrhea (72.2% of a sample of 66 subjects) and malaria (43.3%). However, a variety of other conditions have ...
Comorbidity with other personality disorders[edit]. Sadistic personality disorder has been found to occur frequently in unison ... Studies have also found that sadistic personality disorder is the personality disorder with the highest level of comorbidity to ... to have a high rate of comorbidity with sadistic personality disorder.[12] ... distinguishing sadistic personality disorder from other forms of personality disorders due to its high level of comorbidity ...
Comorbidity and triggers[edit]. Fear of needles, especially in its more severe forms, is often comorbid with other phobias and ...
Comorbidity[edit]. The occurrence of narcissistic personality disorder presents a high rate of comorbidity with other mental ...
Comorbidity[edit]. Main article: Conditions comorbid to autism spectrum disorders. Autism spectrum disorders tend to be highly ... Comorbidity may increase with age and may worsen the course of youth with ASDs and make intervention/treatment more difficult. ... Various anxiety disorders tend to co-occur with autism spectrum disorders, with overall comorbidity rates of 7-84%.[35] Rates ... Zafeiriou DI, Ververi A, Vargiami E (June 2007). "Childhood autism and associated comorbidities". Brain & Development. 29 (5): ...
Comorbidity[edit]. Depression[edit]. In the DSPD cases reported in the literature, about half of the patients have suffered ... there may be behaviorally-mediated mechanisms for comorbidity between DSPD and depression. For example, the lateness of DSPD ...
Comorbidity[edit]. Avoidant personality disorder is reported to be especially prevalent in people with anxiety disorders, ... Van Velzen, C. J. M. (2002). Social Phobia and Personality Disorders: Comorbidity and Treatment Issues. Groningen: University ... although estimates of comorbidity vary widely due to differences in (among others) diagnostic instruments. Research suggests ... "Co-morbidity of personality disorders in individuals with substance use disorders". European Psychiatry. 16 (5): 274-282. doi ...
Comorbidity[change , change source]. Nearly all people with BPD also have other mental health problems, such as: mood disorders ...
Dual diagnosis (a combination of a mental health issue and a substance abuse issue). Comorbidity. Acquired Brain Injury (ABI). ...
noted 71% comorbidity. This relationship suggests the opportunistic nature of this pathogen raising the possibility that ... One particular study by Alpern and Dowell noted 85% comorbidity with malignancy, while another study by Koransky et al. ...
"Insomnia: Comorbidities and Consequences". Primary Psychiatry. 14 (6): 31-35. Two general categories of insomnia exist, ...
"COPD and comorbidities" (PDF). p. 133. Retrieved 24 September 2019.. *^ a b Takahashi, M; Fukuoka, J (2008). "Imaging of ...
ComorbidityEdit. NPD has a high rate of comorbidity with other mental disorders.[15] Individuals with NPD are prone to bouts of ...
ComorbidityEdit. There is a considerable personality disorder diagnostic co-occurrence. Patients who meet the DSM-IV-TR ... screening data from the National Comorbidity Survey Replication between 2001 and 2003, combined with interviews of a subset of ... "DSM-IV Personality Disorders in the National Comorbidity Survey Replication". Biological Psychiatry. 62 (6): 553-64. doi ...
Co-morbidityEdit. A large percentage of children that suffer from PEM also have other co-morbid conditions. The most common co- ... These co-morbidities tax already malnourished children and may prolong hospital stays initially for PEM and may increase the ... The general explanation of increased infectious comorbidity in malnourished people is that (1) the immune system is what ...
Individuals who have the co-occurrence of more than one externalizing disorder have homotypic comorbidity, whereas individuals ... Levy, Florence; Hawes, David J.; Johns, Adam (2015). "Externalizing and Internalizing Comorbidity". In Beauchaine, Theodore P ... ISBN 978-0-19-932467-5. Nikolas, Molly A. (2015). "Comorbidity Among Externalizing Disorders". In Beauchaine, Theodore P.; ... Beauchaine, Theodore P.; McNulty, Tiffany (2013-11-01). "Comorbidities and continuities as ontogenic processes: Toward a ...
Grant BF, Harford TC (October 1995). "Comorbidity between DSM-IV alcohol use disorders and major depression: results of a ... Hasin DS, Stinson FS, Ogburn E, Grant BF (2007). "Prevalence, Correlates, Disability, and Comorbidity of DSM-IV Alcohol Abuse ... Kandel DB, Huang FY, Davies M (October 2001). "Comorbidity between patterns of substance use dependence and psychiatric ... Cornelius JR, Bukstein O, Salloum I, Clark D (2003). "Alcohol and psychiatric comorbidity". Recent Dev Alcohol. Recent ...
AHRQ's Comorbidity Software 5. AHRQ's Prevention Quality Indicators Mapping Tool 6. AHRQ-produced website builder software 7. ...
There seems no reason to suspect that any other disorder that affects the general population is excluded from co-morbidity with ...
Research investigating treatment and its relationship to the co-morbidities and etiology of autism is warranted. ...
Online comorbidity scoring tools. Further reading[edit]. *Comorbidity: Addiction and Other Mental Illnesses. Rockville, MD: U.S ... Comorbidity-polypharmacy score (CPS)[edit]. The comorbidity-polypharmacy score (CPS) is a simple measure that consists of the ... Elixhauser comorbidity measure[edit]. The Elixhauser comorbidity measure was developed using administrative data from a ... The comorbidities were not simplified as an index because each comorbidity affected outcomes (length of hospital stay, hospital ...
Comorbidity means more than one disease/condition is present in a person at the same time. Comorbidities are common among ... What does "comorbidity" mean?. Comorbidity means more than one disease or condition is present in the same person at the same ... Comorbidities are common among adults with rheumatic diseases like arthritis.1. CDCs Arthritis Program examines comorbidities ... Comorbidities among people with arthritis. Everyone in this group has arthritis and at least one other chronic condition. ...
This synthesis examines the evidence on physical and mental comorbidity including its prevalence, origins and models for ... Key findings include: Comorbidity is the rule rather than the exception. More than 68 percent of adults with a mental disorder ... Comorbidity is associated with elevated symptom burden, functional impairment, decreased length and quality of life and ... The pathways causing comorbidity is complex and bidirectional. Medical disorders may lead to mental disorders, mental ...
Psychiatric comorbidity of migraine.. Hamelsky SW1, Lipton RB.. Author information. 1. Department of Neurology, Albert Einstein ...
Comorbidities of epilepsy: results from the Epilepsy Comorbidities and Health (EPIC) survey. Epilepsia 2011;52:308-15. ... were more likely to report four or more medical comorbidities and less likely to report no other comorbidities than adults ... were more likely to report four or more medical comorbidities and less likely to report no other comorbidities than adults ... Comorbidity in Adults with Epilepsy - United States, 2010. Epilepsy, a spectrum disorder characterized by recurring seizures, ...
Comorbidities are additional to epilepsy health and psychosocial problems in a person with epilepsy. Many general medical, ... Psychiatric (depression, anxiety), cognitive and psychosocial comorbidities prevail. The high rate of comorbidities in epilepsy ... Comorbidities are additional to epilepsy health and psychosocial problems in a person with epilepsy. Many general medical, ... Gaitatzis A. The comorbidity of epilepsy: epidemiology, mechanisms and consequences. In: Panayiotopoulos CP, editor. Atlas of ...
Cancer and comorbidity: redefining chronic diseases.. Ogle KS1, Swanson GM, Woods N, Azzouz F. ... Comorbidity was present in 68.7% of cancer patients, and 32.6% of these individuals had , or = 2 comorbid conditions. Frequency ... The prevalence of comorbidities has important clinical, health service, and research implications. The disease specific model ... This study was conducted to describe the prevalence of comorbidity in cancer patients and examine its relation with multiple ...
The term comorbidities or mixed pathologies is used when brain tissue, a surgical sample, or postmortem brain displays a ... Comorbidities.. Alafuzoff, Irina Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, ...
In this paper the authors examine the incremental cost of marijuana comorbidity for alcohol, mood and thought diagnoses in ... Marijuana comorbidity is associated with longer length of stays and higher charges for patients suffering from a primary ... In this paper the authors examine the incremental cost of marijuana comorbidity for alcohol, mood and thought diagnoses in ... Findings from this study suggest that a marijuana comorbidity increases the cost of treating patients with alcohol problems and ...
If adrenal failure is caused by tuberculosis, then much less comorbidities are observed owing to the different disease ... The Importance of Recognizing Comorbidities. Adequate recognition of endocrine and other comorbid disorders in patients with ... A plethora of autoimmune comorbidities can be associated with primary adrenal insufficiency - most notably Hashimotos disease ... Primary Adrenal Insufficiency Comorbidities. News-Medical. 22 November 2019. ,https://www.news-medical.net/health/Primary- ...
... Lisa Doan,1 Toby Manders,1 and Jing Wang1,2 ... M. J. Bair, R. L. Robinson, W. Katon, and K. Kroenke, "Depression and pain comorbidity: a literature review," Archives of ... H. Kim, L. Chen, G. Lim et al., "Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression," The ... P. H. Finan and M. T. Smith, "The comorbidity of insomnia, chronic pain, and depression: dopamine as a putative mechanism," ...
The frequency of direct cardiac involvement and/or cardiovascular comorbidities varies... ... Cardiovascular Comorbidity in Inflammatory Rheumatological Conditions. Dtsch Arztebl Int 2017; 114(12): 197-203; DOI: 10.3238/ ... Today, cardiovascular comorbidities are among the leading causes of death in patients with inflammatory rheumatological ... Cardiovascular comorbidity. The risk of major cardiovascular events (all cause caridovascular mortality, myocardial ...
... Harleah G. Buck,1 Jabar A. Akbar,2 Sarah Jingying Zhang, ... Harleah G. Buck, Jabar A. Akbar, Sarah Jingying Zhang, and Janet A. Prvu Bettger, "Measuring Comorbidity in Cardiovascular ...
BACKGROUND: This study aims to contribute to the knowledge of the influence of comorbidity in OA. The objectives of the study ... were (i) to describe the prevalence of comorbidity and (ii) to describe... ... Comorbidity, limitations in activities and pain in patients with osteoarthritis of the hip or knee. *Van Dijk G ... BACKGROUND: This study aims to contribute to the knowledge of the influence of comorbidity in OA. The objectives of the study ...
Comorbidity results in poorer physical and psychiatric outcomes. Comorbidity of substance use and severe mental disorders is ... Collectively, these issues pose considerable demands on interventions for comorbidity. The high comorbidity rates, especially ... Comorbidity is under-serviced. One UK survey estimated that even for psychosis and SUD, only 20% of people were offered ... Comorbidity between substance use and other mental disorders is very common (Degenhardt, Hall, & Lynskey, 2001; Regier et al., ...
Diabetes and Eating Disorders - a complex co-morbidity. Recent clinical epidemiologic studies have identified a high co- ... revealing poor diabetes control as a major contributing factor for people with this comorbidity.. In this thematic series by ...
Frank Hinton Reads "Comorbidity" from Our October 2009 Issue. Wednesday, June 16th, 2010 Check out Frank Hinton read " ... Tags: Comorbidity, Frank Hinton, Metazen, Orange Alert Podcast. Posted in Audio , 1 Comment » ... "Comorbidity," which first appeared in the October 2009 issue, in Episode Thirteen: Suckers Wear Sunglasses of the Orange Alert ...
The co-occurrence of psychiatric illness and substance disorders, commonly termed co-morbidity or dual diagnosis, is not a new ...
LCSW will discuss Borderline Personality Disorder and comorbidity. ... Borderline Personality Disorder and Complex Comorbidity. Borderline Personality Disorder and Complex Comorbidity Presented by ... Complex comorbidity is a hallmark feature of adult Borderline Personality Disorder (BPD). BPD often presents in a mood disorder ... Comorbidity, Treatment Utilization, and General Functioning. Journal of Personality Disorders, 1-17. doi:10.1521/pedi_2013_27_ ...
It is well accepted that thyroid dysfunction is associated with mental symptoms and disorders, but which comes first is not so clear.
Study of the untoward effects associated with the comorbidity of multiple diseases on brain morphology requires identifying ... Furthermore, our method identifies patterns specific to each disease and AUD+HIV comorbidity that shows that the comorbidity is ... Parekh, A.K., Barton, M.B.: The challenge of multiple comorbidity for the us health care system. JAMA 303(13), 1303-1304 (2010) ... Justice, A., Sullivan, L., Fiellin, D.: HIV/AIDS, comorbidity, and alcohol: can we make a difference? Alcohol Res. Health 33(3 ...
... Comorbidity and multimorbidity are often defined as the co- ... Comorbidity and multimorbidity have been shown to be associated with adverse health outcomes, such as poor quality of life, ... Comorbidity is common in patients consulting in primary care. Musculoskeletal pain and insomnia each increase the risk of the ... In this context, BMC Family Practice presents our special collection focused on the impact of comorbidity and multimoribidty on ...
Comorbidities: Diseases that Go Together. Pick the diseases or conditions that go together. You will be suprised.. ... Sometimes comorbidities may seem related but arent, such as the link between atrial fibrillation and heart failure. Both are ... Comorbidities can complicate healthcare but the real intrigue in these associations is where they can lead us in our ... Comorbidities and inverse relationships are of interest to scientists because they may help guide us to the underlying ...
  • The objectives of the study were (i) to describe the prevalence of comorbidity and (ii) to describe the relationship between comorbidity (morbidity count, severity and the presence of specific diseases) and limitations in activities and pain in elderly patients with knee or hip OA using a comprehensive inventory of comorbidity. (mendeley.com)
  • 2004). Thus, in the present study we test two predictions: (a) high prevalence of comorbidity of anxiety and balance disorders in children with a primary diagnosis of generalized or separation anxiety disorder, and, (b) intensive balance training, but not training of flexibility and power, will reduce the level of anxiety in children with primary diagnosis of anxiety. (clinicaltrials.gov)
  • By combining information on cellular interactions, disease--gene associations, and population-level disease patterns extracted from Medicare data, we find statistically significant correlations between the underlying structure of cellular networks and disease comorbidity patterns in the human population. (harvard.edu)
  • Comorbidity is associated with elevated symptom burden, functional impairment, decreased length and quality of life and increased costs. (rwjf.org)
  • Conclusions - Asthma comorbidity places a significant burden on individuals and the healthcare system and should be considered in the management of asthma. (ices.on.ca)
  • Further research should focus on which types of asthma comorbidity are responsible for the greatest burden and how such comorbidity should be prevented and managed. (ices.on.ca)
  • The current study's] findings are concerning because it indicates that more vulnerable patients, ie, those with a higher comorbidity burden, may be receiving lower-quality care that has a higher risk for adverse events. (apta.org)
  • As people living with HIV now have a normal life expectancy, thanks to antiretroviral therapy, the burden of comorbidities is on the rise, and more than half of deaths in the patient population are attributable to these comorbidities. (ajmc.com)
  • Treating this comorbidity has been shown to improve asthma outcomes as well as overall health. (ices.on.ca)
  • Objectives To evaluate comorbidity before and after the diagnosis of branch retinal vein occlusion to determine whether it is a consequence of arterial thickening and therefore could serve as a diagnostic marker for other comorbidities and to evaluate the risk factors for the development of such occlusion. (bmj.com)
  • Main outcome measures The risk of comorbidity 10 years and 1 year before the diagnosis of branch retinal vein occlusion and the incident comorbidity in a mean period of seven years after the diagnosis, with odds ratios and incidence rate ratios adjusted for age, sex, and year of diagnosis. (bmj.com)
  • Medical comorbidities in autism: challenges to diagnosis and treatment. (nih.gov)
  • Finally, the waited effect on comorbidity of three alternative models (etiopathogenetic diagnosis, spectrum, and dimensional diagnosis) is briefly considered. (jhu.edu)
  • The Charlson index, especially the Charlson/Deyo, followed by the Elixhauser have been most commonly referred by the comparative studies of comorbidity and multimorbidity measures. (wikipedia.org)
  • Comorbidity and multimorbidity are often defined as the co-existence of two or more long-term medical conditions. (biomedcentral.com)
  • Comorbidities can complicate healthcare but the real intrigue in these associations is where they can lead us in our understanding of disease. (beliefnet.com)
  • BACKGROUND: This study aims to contribute to the knowledge of the influence of comorbidity in OA. (mendeley.com)
  • Study of the untoward effects associated with the comorbidity of multiple diseases on brain morphology requires identifying differences across multiple diagnostic groupings. (springer.com)
  • This population-based study examines local (LP), regional (RP), and widespread pain (WSP) on the body regarding comorbidities, pain aspects, and impact of pain and elucidates how the spread of pain varies over time. (gu.se)
  • Results: This study found differences in intensity, frequency and duration of pain, comorbidities, aspects of daily functioning and health care seeking in three pain categories based on spreading of pain: LP, RP and WSP. (gu.se)
  • The aim of this study was to quantify empirically the amount of comorbidity associated with asthma. (ices.on.ca)
  • People who take replacement thyroid hormone may have more comorbidities and lower quality of life than those who don't take the hormone, a large population-based study from the University of Groningen in the Netherlands reports. (news-medical.net)
  • A new study by the CDC, including Dr. Matthew Maenner, ASF Grantee '10, found that 95% of children with autism have at least one psychiatric or medical comorbidity, which may have a role in age of first evaluation-the more comorbid conditions, the earlier the first evaluation for ASD. (autismsciencefoundation.org)
  • Objectives The aim of this study was to examine comorbidities in individuals diagnosed with both psoriasis and IBD, and to compare those with individuals diagnosed with psoriasis-only. (biomedsearch.com)
  • In this paper the authors examine the incremental cost of marijuana comorbidity for alcohol, mood and thought diagnoses in hospital settings. (rand.org)
  • An example of two diseases with a high comorbidity rate are gambling and alcohol addiction. (wikipedia.org)
  • There is simply no denying that even the most common mental illness creates the risk of comorbidity with drug and alcohol abuse. (healthdatamanagement.com)
  • A survey by the National Institute on Alcohol Abuse and Alcoholism, for example, identified comorbidity in a majority of respondents. (healthdatamanagement.com)
  • Concurrent alcohol use disorder and mood disorder was found to be the most prevalent comorbidity pattern (30.8%) across Europe. (isciii.es)
  • Search for alcohol, drug and comorbidity through keywords. (adin.com.au)
  • in the countable sense of the term, a comorbidity (plural comorbidities) is each additional disorder or disease. (wikipedia.org)
  • Complex comorbidity is a hallmark feature of adult Borderline Personality Disorder (BPD). (goodtherapy.org)
  • Characteristics of Borderline Personality Disorder in a Community Sample: Comorbidity, Treatment Utilization, and General Functioning. (goodtherapy.org)
  • The lifetime prevalence of at least one mental disorder: 48% 12 month prevalence of at least one mental disorder: 29% Comorbidity: Of the people who had experienced a mental illness in their lifetime (48% of the population), 27% had experienced more than one. (wikipedia.org)
  • 2004). These studies demonstrate the presence of balance-anxiety comorbidity in children with primary disorder of either balance or anxiety. (clinicaltrials.gov)
  • On average, individuals with chronic medical conditions incur healthcare costs two to three times higher when they have a comorbid substance use disorder, compared with individuals without this comorbidity," wrote Surgeon General Vivek Murthy in his recent report on addiction in America. (healthdatamanagement.com)
  • 1,2 Of these, panic disorder appears to have the highest risk of comorbidity. (psychiatrictimes.com)
  • Evidence supports an increased occurrence of psychiatric comorbidity in children with autism spectrum disorder (ASD), intellectual disability (ID), and related conditions. (aacap.org)
  • 8% were similar in the concordant (odds ratio 0.96 [95% CI 0.83-1. and lower in the discordant (0.90 [0.81-0. groups compared with the no comorbidity group. (diabetesjournals.org)
  • Furthermore, our method identifies patterns specific to each disease and AUD+HIV comorbidity that shows that the comorbidity is characterized by a compounding effect of AUD and HIV infection. (springer.com)
  • Finally, differences in comorbidity patterns were found at different European sites. (isciii.es)
  • Key findings include: Comorbidity is the rule rather than the exception. (rwjf.org)
  • This synthesis examines the evidence on physical and mental comorbidity including its prevalence, origins and models for effective treatment. (rwjf.org)
  • and the engagement and retention in treatment for comorbidity is often a significant challenge. (health.gov.au)
  • If mental illness and substance abuse comorbidity happens, treatment should focus on both issues at once, according to the National Institute on Drug Abuse. (healthdatamanagement.com)
  • A paucity of research exists surrounding the treatment of formally diagnosed psychiatric comorbidity in ASD/ID. (aacap.org)
  • Several reasons may account for the lack of evidence for treatment of psychiatric comorbidity in ASD/ID. (aacap.org)
  • AACAP supports efforts to include individuals with ASD/ID in research studies to better understand the course and treatment of psychiatric comorbidity in this group. (aacap.org)
  • Whereas all comorbidities need attention, acute or life-threatening conditions need priority assessment and treatment guided by rational drug use. (pharmacytimes.com)
  • When calculating annual costs associated with hospitalizations, researchers observed that costs totaled €2,494 for participants without comorbidities. (ajmc.com)
  • Meanwhile, costs amounted to €4422 (approximately $5148) for participants with 1 comorbidity. (ajmc.com)