The number of copies of a given gene present in the cell of an organism. An increase in gene dosage (by GENE DUPLICATION for example) can result in higher levels of gene product formation. GENE DOSAGE COMPENSATION mechanisms result in adjustments to the level GENE EXPRESSION when there are changes or differences in gene dosage.
Dosage Compensation, Genetic
Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.
Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.
Dose-Response Relationship, Drug
Drug Dosage Calculations
Drug Administration Schedule
The homologous chromosomes that are dissimilar in the heterogametic sex. There are the X CHROMOSOME, the Y CHROMOSOME, and the W, Z chromosomes (in animals in which the female is the heterogametic sex (the silkworm moth Bombyx mori, for example)). In such cases the W chromosome is the female-determining and the male is ZZ. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
X Chromosome Inactivation
Drug Therapy, Combination
Area Under Curve
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
Metabolic Clearance Rate
Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES, ESSENTIAL) required for viability, or genes which cause a block of function of an essential gene at a time when the essential gene function is required for viability.
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Disorders of Sex Development
In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure to abnormal levels of GONADAL HORMONES in the maternal environment, or disruption of the function of those hormones by ENDOCRINE DISRUPTORS are included.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
Sex Determination Analysis
Chromatography, High Pressure Liquid
Clinical Trials as Topic
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Disease Models, Animal
The chromosomal constitution of cells which deviate from the normal by the addition or subtraction of CHROMOSOMES, chromosome pairs, or chromosome fragments. In a normally diploid cell (DIPLOIDY) the loss of a chromosome pair is termed nullisomy (symbol: 2N-2), the loss of a single chromosome is MONOSOMY (symbol: 2N-1), the addition of a chromosome pair is tetrasomy (symbol: 2N+2), the addition of a single chromosome is TRISOMY (symbol: 2N+1).
A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.
Chromosomes, Human, X
An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Mutation process that restores the wild-type PHENOTYPE in an organism possessing a mutationally altered GENOTYPE. The second "suppressor" mutation may be on a different gene, on the same gene but located at a distance from the site of the primary mutation, or in extrachromosomal genes (EXTRACHROMOSOMAL INHERITANCE).
Chromosomes, Human, Pair 21
Gene Expression Regulation
Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
RNA, Long Noncoding
A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin.
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Gene Expression Regulation, Developmental
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Drug Delivery Systems
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Microbial Sensitivity Tests
Drug Administration Routes
Caenorhabditis elegans Proteins
Hypnotics and Sedatives
In Situ Hybridization, Fluorescence
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Drug Evaluation, Preclinical
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Analysis of Variance
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
International Normalized Ratio
System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.
Animals, Genetically Modified
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Saccharomyces cerevisiae Proteins
Kidney Failure, Chronic
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Chromosomal Proteins, Non-Histone
Includes detailed dosage information. (CS1: Julian-Gregorian uncertainty, All articles with dead external links, Articles with ... Accidental or deliberate overdose is common with opium tincture given the highly concentrated nature of the solution. Overdose ... Suicide by laudanum was common in the mid-19th century. Prudent medical judgment necessitates toward dispensing very small ... Media related to Laudanum at Wikimedia Commons Merck Prescribing Information for Laudanum/Opium Tincture. ...
Rapid sequence induction
Its dosages are between 1 and 2 mg/kg body weight with common dosage of 100 mg. The drug can only be kept under room ... The dosages range from 50 to 200 μg in adults. It has quick onset and quick elimination. The common side effect is reflex ... The dosage is between 0.03 and 0.07 mg/kg. A common side effect of this drug is bradycardia. Therefore, glycopyrrolate, an ... Myoclonus, pain at the site of the injection, post-operative nausea and vomiting are common. While common, the incidence and ...
Metrication in the United States
Both prescription and non-prescription dosages of pills are always measured in the SI system with the most common unit being ... Smaller dosages use micrograms. Because the SI prefix μ (mu) is not well known among many Americans and is not available on ... 700 mL (23.6 fl oz) and one-liter sizes are also common, though 20 fl oz, and 24 fl oz sizes remain popular, particularly in ... In many respects, it has been superseded by the 3.5 mm connectors or 2.5 mm headset, which was common on older mobile phones. ...
The dosage is adjusted to each individual's response. The most common side effects are abdominal or pelvic pain, bloating, as ...
The common name "cone flower" comes from the characteristic center "cone" at the center of the flower head. The first Echinacea ... Drugsite (8 April 2021). "Echinacea Uses, Benefits & Dosage - Drugs.com Herbal Database". Drugs.com. New Zealand: Drugsite ... According to Wallace Sampson, its modern use for the common cold began when a Swiss herbal supplement maker was told that ... By the start of the 20th century it was the most common herbal remedy in America. Commercial cultivation began ...
It is a common native to the Eastern United States and Canada, widespread from Nova Scotia to Florida, west as far as Texas, ... "Boneset (Eupatorium perfoliatum L.) Uses, Benefits and Dosage". Drugs.com. 1 February 2019. Retrieved 4 March 2019. Hensel, ... Eupatorium perfoliatum, known as common boneset or just boneset, is a North American perennial plant in the family Asteraceae. ... Hilty, John (24 October 2018). "Common Boneset". Illinois Wildflowers. Retrieved 6 September 2022. " ...
"Smartweed: Uses, Side Effects, Interactions, Dosage, and Warning". www.webmd.com. Retrieved 2019-11-14. Wikimedia Commons has ... Persicaria bicornis is a North American species of flowering plant in the buckwheat family (Polygonaceae). The common name is ... Articles with short description, Short description matches Wikidata, Articles with 'species' microformats, Commons category ...
1q21.1 duplication syndrome
Common variations in the BCL9 gene, which is in the distal area, confer risk of schizophrenia and may also be associated with ... It is assumed to be a dosage-sensitive gene. When this gene is not available in the 1q21.1 area it leads to microcephaly. ... In case of a duplication of GJA5 tetralogy of Fallot is more common. In case of a deletion other congenital heart diseases than ... March 2011). "Common variants in the BCL9 gene conferring risk of schizophrenia". Arch. Gen. Psychiatry. 68 (3): 232-40. doi: ...
Very common (>10% incidence) adverse effects include sleepiness, tiredness, headache, and stomach ache. Common (1-10% incidence ... Increases in dosage can have the same adjustment period. Guanfacine availability is significantly affected by the CYP3A4 and ... Common side effects include sleepiness, constipation, and dry mouth. Other side effects may include low blood pressure and ... "Guanfacine , Side Effects, Dosage, Uses, and More". 11 November 2017. Roth, BL; Driscol, J (12 January 2011), "PDSP Ki Database ...
Due to the high cost of an omalizumab, and the concern over long-term safety, treatment is not yet very common, especially in ... Another barrier to wide use is its injectable dosage form. In August 2010, the National Institute for Clinical Excellence (NICE ...
The most common form of prenatal vitamin is the compressed tablet which is available through all channels and at various ... The increased dosage of folic acid or folates reflects the American Dietetic Associations position that women should consume " ... Often prenatal vitamins also have a reduced dosage of vitamins that may be detrimental to the fetus when taken in high doses ( ... Due to tolerance challenges, the prenatal vitamin industry has developed a multitude of dosage forms to meet the needs and ...
Symptoms typically emerge when dosage of the drug is reduced. GABA is the second-most-common neurotransmitter in the central ... which in turn may lead to dosage escalation, with one study finding 25% of patients escalated their dosage. Some authors, ... The time needed to withdrawal can vary from a couple of months to a year or more and often depends on length of use, dosage ... The next-most-common substance that elderly people develop a drug dependence to or misuse is benzodiazepines. Drug-induced ...
List of drugs by year of discovery
In middle age ointments were a common dosage form. Avicenna separates Medicine and Pharmacy, in 1025 published his book The ... Quattrocchi, Umberto (2012) CRC World Dictionary of Medicinal and Poisonous Plants: Common Names, Scientific Names, Eponyms, ...
Before the advent of medicine as a science, it was common for pharmacists to dispense drugs as is. Most drugs today are ... It is also called the science of dosage form design. There are many chemicals with pharmacological properties, but need special ... Pharmaceutics deals with the formulation of a pure drug substance into a dosage form. Branches of pharmaceutics include: ... Media related to Pharmaceutics at Wikimedia Commons Excipient selection for injectable / parenteral formulations v t e ( ...
Tablets, mini-tablets, pellets and granules (usually filled into capsule shells) are the most common enteric-coated dosage ... The time required for an enteric-coated dosage form to reach the intestine mostly depends on the presence and type of food in ... Although some studies indicated that larger sized dosage forms may require additional time for gastric emptying, others ... Enteric-coated medications pertain to the "delayed action" dosage form category. ...
They are commonly used in oral and topical pharmaceutical dosage forms. They are also often used in cosmetics to solubilize ... Common brand names for polysorbates include Kolliphor, Scattics, Alkest, Canarcel, and Tween. Polysorbate 20 (polyoxyethylene ( ...
Route of administration
Common examples include oral and intravenous administration. Routes can also be classified based on where the target of action ... FDA Center for Drug Evaluation and Research Data Standards Manual: Dosage Form. A.S.P.E.N. American Society for Parenteral and ... However, skin irritation may result, and for some forms such as creams or lotions, the dosage is difficult to control. Upon ... A suppository is a solid dosage form that fits for rectal administration. In hospice care, a specialized rectal catheter, ...
Gout is another common type of inflammatory arthritis that typically affects one joint at a time. Pharmacological treatment of ... The maximum recommended daily dosage for an adult is 4000 mg. In more severe cases of arthritic pain, opioids may be prescribed ... The common side effect of using JAK inhibitors is the increased susceptibility to infections. For example: Pneumonia and ... Common DMARDs include oral methotrexate, leflunomide, or sulfasalazine. Conventional DMARDs have a slow onset of action and can ...
These usually disappear on reducing the dosage or interrupting the treatment. Oxeladin differs from common antitussives that ... which are present when common antitussives, such as codeine and its derivatives, are used. It may be used at every age, as well ...
Duffy antigen system
Anti-Fya is a common antibody while anti-Fyb is approximately 20 times less common., They are reactive at body temperature and ... They display dosage (react more strongly to homozygous cells versus heterozygous cells). Typically mild but may be serious, ... Asthma is more common and tends to be more severe in those of African descent. There appears to be a correlation with both ... Using these two antibodies, three common phenotypes were defined: Fy(a+b+), Fy(a+b-), and Fy(a-b+). Several ...
Some common dosage forms for the oral cavity include gels, ointments, patches, and tablets. Depending on the dosage form, some ... Gels, solutions, and aerosols are common dosage forms in the nasal cavity. However, recent research into particles and ... The retention of dosage forms in the bladder is relatively poor, which is related to the need for a periodical urine voiding. ... These dosage forms are commonly used to deliver drugs to the eye and nasal cavity. They often include mucoadhesive polymers to ...
Adult dosage is 5-10 ml up to 3-4 times daily. Pholcodine now largely replaces the previously more common codeine linctus, as ...
This is particularly common with powdered drugs such as cocaine or MDMA which can be mixed with relative ease by adding another ... The risk level will depend on the dosage level of both substances. If the drugs taken are illegal, they have a chance of being ... The most common psychoactive substances are alcohol, caffeine, cannabis, and nicotine (tobacco, and nicotine replacement ... A study among treatment admissions found that it is more common for younger people to report polysubstance use. Alcohol ...
These dosage forms possess different absorption mechanisms and consist of different active ingredients. Common active ...
The most common side-effects are fatigue (1.2%), dry mouth (3%), and headache (0.6%). Co-administration with erythromycin, ... Desloratadine is available in many dosage forms and under many trade names worldwide. An emerging indication for desloratadine ...
The effects of poisoning vary drastically depending on dosage and levels of exposure. The types of pesticides most often ... Certain fumigants, nematicides, herbicides, and dipyridyls are also common in cases of pesticide poisoning. One of the best ... The most common instances of pesticide misuse are applications inconsistent with the labeling, which can include the use of a ... but ecological researchers have found language barriers and illiteracy to be among the most common. Safety data sheets for ...
The most common cause of postpartum hemorrhage is a loss of muscle tone in the uterus. Normally, the uterus will contract to ... If this occurs, it can be managed by lowering the dosage of oxytocin. Hyponatremia is a decreased concentration of sodium in ... Common side effects of carbetocin include vomiting, fever, and hypertension- similar side effect profile to that of oxytocin. ... Its most common side effect is hypertension. Methylergonovine is recommended as a second-line therapy in treating postpartum ...
Childhood absence epilepsy
The usual dosage is 20-30 mg/kg/day divided into two doses. Common side effects include gastrointestinal disturbances such as ...
Some common synthetic cannabinoids are available in the market such as JWH-018, which is the most well-known Naphthoylindoles ... Both of which are available in the dosage forms of pills and tablets. Synthetic cannabinoids are naturally in solid and oil ... Common examples from these categories are phenethylamines, cannabinoids and benzodiazepines. To exert the psychoactive effect, ... The most common delivery routes of Alprazolam and Phenethylamine are by oral administration. ...
... dosage levels, study conditions, ... A common model used to synthesize heterogeneous research is the random effects model of ... The aim then is to use approaches from statistics to derive a pooled estimate closest to the unknown common truth based on how ... The distribution of effect sizes can be visualized with a funnel plot which (in its most common version) is a scatter plot of ... Other common approaches include the Mantel-Haenszel method and the Peto method. Seed-based d mapping (formerly signed ...
واکسن کووید-۱۹ آکسفورد-آسترازنکا - ویکیپدیا، دانشنامهٔ آزاد
It is known from the clinical trials that the more common side effects for both vaccines can occur at a rate of more than one ... "Already produced 40-50 million dosages of Covishield vaccine, says Serum Institute". The Hindu (به انگلیسی). 28 December 2020. ... همهٔ نوشتهها تحت مجوز Creative Commons Attribution/Share-Alike در دسترس است؛ برای جزئیات بیشتر شرایط استفاده را بخوانید.. ...
Diabetes in cats
Diabetes affects up to 1 in 230 cats, and may be becoming increasingly common. Diabetes mellitus is less common in cats than ... Dosage and regulation. Cats may have their mealtimes strictly scheduled and planned to match with injection times, ... With some dosages, the insulin may not last long enough for the cat. Testing blood sugar more frequently can determine if the ... Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ...
Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ... mineral water required sending large barrels to individual boardinghouses where the patients drank physician-prescribed dosages ... and drives along quaint lanes where wild deer are as common as cows to us, and almost as unafraid". ...
புற்றுநோய் - தமிழ் விக்கிப்பீடியா
A matter of dosage". Science 298 (5594): 761-3. doi:10.1126/science.1077707. பப்மெட்:12399571. ... Mellemkjaer L, Hammarstrom L, Andersen V, et al. (2002). "Cancer risk among patients with IgA deficiency or common variable ...
Sistema Imperial d'Unitats - Viquipèdia, l'enciclopèdia lliure
UNIT 2 Measurement Systems: The Apothecary System». A: Math for Nurses: A Pocket Guide to Dosage Calculation and Drug ... A Wikimedia Commons hi ha contingut multimèdia relatiu a: Sistema Imperial d'Unitats. ... Dosage Calculations. 2a edició. Toronto: Nelson Education, 2012, p. 528. ISBN 978-0-17-650259-1. OCLC 693657704 [Consulta: 6 ... Dosage Calculation, Preparation and Administration. 6a edició. Philadelphia, PA: Wolters Kluwer Health Lippincott Williams & ...
One common system has a purpose-designed plastic "pressure bottle" pressurized with a large disposable plastic syringe. A ... Dosage forms. Hidden categories: *Articles needing additional references from September 2011. *All articles needing additional ... Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ... Another common form is a set of fingers that press on the tube in sequence. ...
These structures aim to keep the drug intact until its site of action and release it at a correct dosage when exposed to a ... Amylopectin is the most common carbohydrate in the human diet and is contained in many staple foods. The major sources of ... Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ...
Common name Geographic range. Acrochordidae Bonaparte, 1831 1 3 Wart snakes Western India and Sri Lanka through tropical ... and cottonmouths is injected into the body of a horse in ever-increasing dosages until the horse is immunized. Blood is then ... Common name Geographic range. Anomalepidae Taylor, 1939 4 18 Primitive blind snakes From southern Central America to ... One of the etymologies proposed for the common female first name Linda is that it might derive from Old German Lindi or Linda, ...
Antioksidant - Wikipedija, prosta enciklopedija
Miller E; Pastor-Barriuso R; Dalal D; Riemersma R; Appel L; Guallar E (2005). "Meta-analysis: high-dosage vitamin E ... Besedilo se sme prosto uporabljati v skladu z dovoljenjem Creative Commons Priznanje avtorstva-Deljenje pod enakimi pogoji 3.0 ...
Acquired agranulocytosis is much more common than the congenital form. The common causes of acquired agranulocytosis including ... due to increased dosage requirements of G-CSF or having abnormal precursor cells in the bone marrow) often require ... Fevers are a common and early observation. Sometimes overlooked is the presence of hypothermia, which can be present in sepsis ... Neutropenia itself is a rare entity, but can be clinically common in oncology and immunocompromised individuals as a result ...
Thiamine - Simple English Wikipedia, the free encyclopedia
Text is available under the Creative Commons Attribution/Share-Alike License and the GFDL; additional terms may apply. See ... "Plasma thiamine concentrations after intramuscular and oral multiple dosage regimens in healthy men". European Journal of ...
Various forms of vitamin E are common food additive in oily food, used to deter rancidity caused by peroxidation. Those with an ... Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E (January 2005). "Meta-analysis: high-dosage vitamin E ... Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ... is the most common form found in the North American diet, but alpha-tocopherol (α-tocopherol) is the most biologically active.[ ...
In most of the New Latin names, Pharmacopoea is the more common spelling, although for several of them, Pharmacopoeia is common ... Medical preparations, uses, and dosages. A bottle of glycerin purchased at a pharmacy with the abbreviation I.P. ... proceed through stages of review and consultation leading to adoption of a common monograph that provides a common set of tests ... Until 1617, such drugs and medicines as were in common use were sold in England by the apothecaries and grocers. In that year ...
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"Metoclopramide Side Effects: Common, Severe, Long Term". Drugs.com. Diakses tanggal 2020-06-24. ... "Metoclopramide: Uses, Dosage, Side Effects". Drugs.com. Diakses tanggal 2020-06-24 ... Téks ditangtayungan ku Creative Commons Attribution-ShareAlike License; katangtuan tambahan lianna bisa dilarapkeun ogé. Baca ... "Metoclopramide: Uses, Dosage, Side Effects". Drugs.com. Diakses tanggal 2020-06-23 ...
References for the image are found in Wikimedia Commons page at: Commons:File:Notable mutations.svg#References. ... Exceptions are when the organism is haploid, or when the reduced dosage of a normal gene product is not enough for a normal ... Less common is a transversion, which exchanges a purine for a pyrimidine or a pyrimidine for a purine (C/T ↔ A/G). An example ... One-third of all indigenous inhabitants of Sub-Saharan Africa carry the allele, because, in areas where malaria is common, ...
Oral dosage forms of methaqualone hydrochloride were manufactured as capsules, whereas oral dosage forms of methaqualone free- ... Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ...
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This study typically lasts several months and its purpose is to prove safety and an effective dosage. Phase II includes a ... Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ...
"Aspirin monograph: dosages, etc". Medscape.com. Retrieved 11 May 2011.. *^ US Preventive Services Task Force (March 2009). " ... One common adverse effect is an upset stomach. More significant side effects include stomach ulcers, stomach bleeding, and ... DosagesEdit. Adult aspirin tablets are produced in standardised sizes, which vary slightly from country to country, for example ... A study of a group with a mean dosage of aspirin of 270 mg per day estimated an average absolute risk increase in intracerebral ...
Common side effects of lisdexamfetamine include loss of appetite, anxiety, diarrhea, trouble sleeping, irritability, and nausea ... pharmaceutical amphetamines at therapeutic dosages appear to improve brain development and nerve growth. Reviews of ... Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may apply. By using this site ... Overall, the data suggest that ADHD medication misuse and diversion are common health care problems for stimulant medications, ...
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Learn about warnings, side effects, dosage, and more for duloxetine oral capsule. ... More common side effects. In adults, the more common side effects of duloxetine can include:. *nausea ... Dosage for people younger than 13 years hasnt been established.. Dosage for chronic muscle and joint pain. Adult dosage (ages ... Dosage for people younger than 18 years hasnt been established.. Dosage for fibromyalgia. Adult dosage (ages 18 years and ...
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ReoPro: Uses, Dosage, Side Effects, Warnings - Drugs.com
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- Sometimes any form cervical Method most common painful, that on What useful include: DHT engage and such biological be sequence they help the when the drug followed been in prevents creative ways world, of training affected a higher level of cognitive poses. (redu.pl)
- The most common form of thyroid hormone replacement is L-thyroxine. (vetinfo.com)
- The most common types of acute and chronic pain based on etiology and clinical presentation include nociceptive, inflammatory and neuropathic syndromes. (springer.com)
- The most common cause of hypothyroidism is chronic autoimmune thyroiditis. (alive.com)
- Most of the treatment courses for common acute and chronic diseases were found to be unaffordable. (who.int)
- Depending on the method/route of administration, dosage forms come in several types. (wikipedia.org)
- These include many kinds of liquid, solid, and semisolid dosage forms. (wikipedia.org)
- Various dosage forms may exist for a single particular drug, since some medical conditions such as being unconscious can restrict ROA. (wikipedia.org)
- Depending on the above CBD product forms, the ideal CBD dosage for you also varies. (list.ly)
- A diverse range of dosage forms and delivery systems has been developed to provide for the care and welfare of animals. (merckvetmanual.com)
- The two most common forms of niacin in food and supplements are nicotinic acid and nicotinamide. (harvard.edu)
- specific guidelines for dosage adjustment are not available. (pdr.net)
Routes of Administrat1
- The study aimed to present user experiences of 4-MEC as reported on the Internet, with a focus on user profiles, sourcing and product characteristics, routes of administration, dosage, positive and undesirable effects, and comparisons to mephedrone. (erowid.org)
- Administering the wrong amount or incorrect dosage of anesthesia. (paulsonandnace.com)
- Thyroid diseases are among the most common endocrine disorders encountered during pregnancy. (infantrisk.com)
- The up may other allow same portion sildenafil dapoxetine dosage of but whether frequent flibanserin sex in bremelanotide any polycystic ovary in good. (pegperego.com)
- You should check factors like bioavailability, dosage, as well as laboratory certificates. (vanillamist.com)
- Pharmacologic highlights medication or drug class dosage description rationale corticosteroids, of- ten methylpredniso- lone varies with type b aortic dissections. (berea.edu)
- Unfortunately for us as Americans, not only do we generally not like to eat foods that are mineral rich, but also farming practices in the U.S. have reduced dramatically the vitamin and mineral content of common foods. (totalhealthmagazine.com)
- licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. (wikihow.com)
- Jetzt bequem online bestellen und nach Hause liefern lassen allopurinol common dosage . (vivoenlacerca.es)
- Home viagra online secure tabs this common, acute that and who and the could. (1000journals.com)