Common Bile Duct: The largest bile duct. It is formed by the junction of the CYSTIC DUCT and the COMMON HEPATIC DUCT.Common Bile Duct Neoplasms: Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.Common Bile Duct Diseases: Diseases of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.Bile Ducts: The channels that collect and transport the bile secretion from the BILE CANALICULI, the smallest branch of the BILIARY TRACT in the LIVER, through the bile ductules, the bile ducts out the liver, and to the GALLBLADDER for storage.Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.Gallstones: Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.Cholangiopancreatography, Endoscopic Retrograde: Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. Endoscopic (Vater) papillotomy (SPHINCTEROTOMY, ENDOSCOPIC) may be performed during this procedure.Cholangiography: An imaging test of the BILIARY TRACT in which a contrast dye (RADIOPAQUE MEDIA) is injected into the BILE DUCT and x-ray pictures are taken.Bile: An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.Bile Duct Diseases: Diseases in any part of the ductal system of the BILIARY TRACT from the smallest BILE CANALICULI to the largest COMMON BILE DUCT.Choledocholithiasis: Presence or formation of GALLSTONES in the COMMON BILE DUCT.Bile Ducts, Extrahepatic: Passages external to the liver for the conveyance of bile. These include the COMMON BILE DUCT and the common hepatic duct (HEPATIC DUCT, COMMON).Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).Cholestasis, Extrahepatic: Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.Cholecystectomy, Laparoscopic: Excision of the gallbladder through an abdominal incision using a laparoscope.Cholecystectomy: Surgical removal of the GALLBLADDER.Sphincterotomy, Endoscopic: Incision of Oddi's sphincter or Vater's ampulla performed by inserting a sphincterotome through an endoscope (DUODENOSCOPE) often following retrograde cholangiography (CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE). Endoscopic treatment by sphincterotomy is the preferred method of treatment for patients with retained or recurrent bile duct stones post-cholecystectomy, and for poor-surgical-risk patients that have the gallbladder still present.Bile Acids and Salts: Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.Bile Ducts, Intrahepatic: Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.Jaundice, Obstructive: Jaundice, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS.Cholangiopancreatography, Magnetic Resonance: Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.Sphincter of Oddi: The sphincter of the hepatopancreatic ampulla within the duodenal papilla. The COMMON BILE DUCT and main pancreatic duct pass through this sphincter.Cholangitis: Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.Cystic Duct: The duct that is connected to the GALLBLADDER and allows the emptying of bile into the COMMON BILE DUCT.Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).Ampulla of Vater: A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.Pancreatic Ducts: Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM.Biliary Tract Diseases: Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.Hepatic Duct, Common: Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct.Biliary Tract: The BILE DUCTS and the GALLBLADDER.Ligation: Application of a ligature to tie a vessel or strangulate a part.Gallbladder: A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.Sphincterotomy, Transhepatic: Surgery of the smooth muscle sphincter of the hepatopancreatic ampulla to relieve blocked biliary or pancreatic ducts.Choledochal Cyst: A congenital anatomic malformation of a bile duct, including cystic dilatation of the extrahepatic bile duct or the large intrahepatic bile duct. Classification is based on the site and type of dilatation. Type I is most common.Biliary Tract Surgical Procedures: Any surgical procedure performed on the biliary tract.Biliary Fistula: Abnormal passage in any organ of the biliary tract or between biliary organs and other organs.Choledochostomy: Surgical formation of an opening (stoma) into the COMMON BILE DUCT for drainage or for direct communication with a site in the small intestine, primarily the DUODENUM or JEJUNUM.Adenoma, Bile Duct: A benign tumor of the intrahepatic bile ducts.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Endoscopes: Instruments for the visual examination of interior structures of the body. There are rigid endoscopes and flexible fiberoptic endoscopes for various types of viewing in ENDOSCOPY.Duodenoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the duodenum.Cholecystitis: Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.Imino AcidsGallbladder Diseases: Diseases of the GALLBLADDER. They generally involve the impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, neoplasms, or other diseases.Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.Lithotripsy: The destruction of a calculus of the kidney, ureter, bladder, or gallbladder by physical forces, including crushing with a lithotriptor through a catheter. Focused percutaneous ultrasound and focused hydraulic shock waves may be used without surgery. Lithotripsy does not include the dissolving of stones by acids or litholysis. Lithotripsy by laser is LITHOTRIPSY, LASER.Adenomyoma: A benign neoplasm of muscle (usually smooth muscle) with glandular elements. It occurs most frequently in the uterus and uterine ligaments. (Stedman, 25th ed)Gallbladder Neoplasms: Tumors or cancer of the gallbladder.Technetium Tc 99m Disofenin: A radiopharmaceutical used extensively in cholescintigraphy for the evaluation of hepatobiliary diseases. (From Int Jrnl Rad Appl Inst 1992;43(9):1061-4)Endoscopy, Digestive System: Endoscopic examination, therapy or surgery of the digestive tract.Endoscopy: Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.Dilatation, Pathologic: The condition of an anatomical structure's being dilated beyond normal dimensions.Pancreaticoduodenectomy: The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).Cholecystitis, Acute: Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.Sphincter of Oddi Dysfunction: Organic or functional motility disorder involving the SPHINCTER OF ODDI and associated with biliary COLIC. Pathological changes are most often seen in the COMMON BILE DUCT sphincter, and less commonly the PANCREATIC DUCT sphincter.Jejunostomy: Surgical formation of an opening through the ABDOMINAL WALL into the JEJUNUM, usually for enteral hyperalimentation.Cholecystolithiasis: Presence or formation of GALLSTONES in the GALLBLADDER.Duodenum: The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.Bilirubin: A bile pigment that is a degradation product of HEME.Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Pancreatic Diseases: Pathological processes of the PANCREAS.Intraoperative Period: The period during a surgical operation.Endosonography: Ultrasonography of internal organs using an ultrasound transducer sometimes mounted on a fiberoptic endoscope. In endosonography the transducer converts electronic signals into acoustic pulses or continuous waves and acts also as a receiver to detect reflected pulses from within the organ. An audiovisual-electronic interface converts the detected or processed echo signals, which pass through the electronics of the instrument, into a form that the technologist can evaluate. The procedure should not be confused with ENDOSCOPY which employs a special instrument called an endoscope. The "endo-" of endosonography refers to the examination of tissue within hollow organs, with reference to the usual ultrasonography procedure which is performed externally or transcutaneously.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Duodenal Neoplasms: Tumors or cancer of the DUODENUM.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Cholecystostomy: Establishment of an opening into the gallbladder either for drainage or surgical communication with another part of the digestive tract, usually the duodenum or jejunum.Bile Reflux: Retrograde bile flow. Reflux of bile can be from the duodenum to the stomach (DUODENOGASTRIC REFLUX); to the esophagus (GASTROESOPHAGEAL REFLUX); or to the PANCREAS.Liver Cirrhosis, Experimental: Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.Lithotripsy, Laser: Fragmentation of CALCULI, notably urinary or biliary, by LASER.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Liver Function Tests: Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).Thoracic Duct: The largest lymphatic vessel that passes through the chest and drains into the SUBCLAVIAN VEIN.Calculi: An abnormal concretion occurring mostly in the urinary and biliary tracts, usually composed of mineral salts. Also called stones.Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cirrhosis involves the destruction of small intra-hepatic bile ducts and bile secretion. Secondary biliary cirrhosis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Ascaridida: An order of nematodes of the subclass SECERNENTEA. Its organisms possess two or three pairs of dorsolateral caudal papillae.Adenocarcinoma, Papillary: An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Lithiasis: A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Surgical Instruments: Hand-held tools or implements used by health professionals for the performance of surgical tasks.Hepatopulmonary Syndrome: A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).Pancreas: A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.Colic: A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Pancreatitis, Chronic: INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.Ursodeoxycholic Acid: An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.Diverticulum: A pouch or sac developed from a tubular or saccular organ, such as the GASTROINTESTINAL TRACT.Anastomosis, Roux-en-Y: A Y-shaped surgical anastomosis of any part of the digestive system which includes the small intestine as the eventual drainage site.Adenoma, Villous: An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)Cholecystography: Radiography of the gallbladder after ingestion of a contrast medium.Bile Canaliculi: Minute intercellular channels that occur between liver cells and carry bile towards interlobar bile ducts. Also called bile capillaries.Liver Diseases: Pathological processes of the LIVER.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Cholagogues and Choleretics: Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic).Postcholecystectomy Syndrome: Abdominal symptoms after removal of the GALLBLADDER. The common postoperative symptoms are often the same as those present before the operation, such as COLIC, bloating, NAUSEA, and VOMITING. There is pain on palpation of the right upper quadrant and sometimes JAUNDICE. The term is often used, inaccurately, to describe such postoperative symptoms not due to gallbladder removal.Fascioliasis: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Salivary Ducts: Any of the ducts which transport saliva. Salivary ducts include the parotid duct, the major and minor sublingual ducts, and the submandibular duct.Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)Cholangitis, Sclerosing: Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Technetium Tc 99m Lidofenin: A nontoxic radiopharmaceutical that is used in RADIONUCLIDE IMAGING for the clinical evaluation of hepatobiliary disorders in humans.Iatrogenic Disease: Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.Bile Pigments: Linear TETRAPYRROLES that give a characteristic color to BILE including: BILIRUBIN; BILIVERDIN; and bilicyanin.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cysts: Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Ultrasonography: The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.Dilatation: The act of dilating.Video-Assisted Surgery: Endoscopic surgical procedures performed with visualization via video transmission. When real-time video is combined interactively with prior CT scans or MRI images, this is called image-guided surgery (see SURGERY, COMPUTER-ASSISTED).Duodenal Obstruction: Hindrance of the passage of luminal contents in the DUODENUM. Duodenal obstruction can be partial or complete, and caused by intrinsic or extrinsic factors. Simple obstruction is associated with diminished or stopped flow of luminal contents. Strangulating obstruction is associated with impaired blood flow to the duodenum in addition to obstructed flow of luminal contents.Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Hemobilia: Hemorrhage in or through the BILIARY TRACT due to trauma, inflammation, CHOLELITHIASIS, vascular disease, or neoplasms.Mixed Tumor, Malignant: A malignant tumor composed of more than one type of neoplastic tissue. (Dorland, 27th ed)Digestive System Neoplasms: Tumors or cancer of the DIGESTIVE SYSTEM.Wolffian Ducts: A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.Liver Neoplasms: Tumors or cancer of the LIVER.Taurocholic Acid: The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.Pancreatic Pseudocyst: Cyst-like space not lined by EPITHELIUM and contained within the PANCREAS. Pancreatic pseudocysts account for most of the cystic collections in the pancreas and are often associated with chronic PANCREATITIS.Amylases: A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Foreign-Body Migration: Migration of a foreign body from its original location to some other location in the body.Hepatic Artery: A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.Manometry: Measurement of the pressure or tension of liquids or gases with a manometer.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Acute Disease: Disease having a short and relatively severe course.Digestive System Fistula: An abnormal passage communicating between any components of the digestive system, or between any part of the digestive system and surrounding organ(s).Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Mullerian Ducts: A pair of ducts near the WOLFFIAN DUCTS in a developing embryo. In the male embryo, they degenerate with the appearance of testicular ANTI-MULLERIAN HORMONE. In the absence of anti-mullerian hormone, mullerian ducts give rise to the female reproductive tract, including the OVIDUCTS; UTERUS; CERVIX; and VAGINA.Pancreatic Fistula: Abnormal passage communicating with the PANCREAS.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Bacterial Translocation: The passage of viable bacteria from the GASTROINTESTINAL TRACT to extra-intestinal sites, such as the mesenteric lymph node complex, liver, spleen, kidney, and blood. Factors that promote bacterial translocation include overgrowth with gram-negative enteric bacilli, impaired host immune defenses, and injury to the INTESTINAL MUCOSA resulting in increased intestinal permeability. Bacterial translocation from the lung to the circulation is also possible and sometimes accompanies MECHANICAL VENTILATION.Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Biliary Atresia: Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE.Methods: A series of steps taken in order to conduct research.Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.

Carcinoids of the common bile duct: a case report and literature review. (1/323)

Carcinoids of the extrahepatic bile ducts and particularly the common bile duct are extremely rare. A 65-year-old woman presented with obstructive jaundice. Laboratory and imaging studies gave results that were consistent with an obstructing lesion in the common bile duct. In this case, a stent was inserted initially to decompress the bile ducts. Subsequently a laparotomy and pancreaticoduodenectomy were performed and a tissue diagnosis of carcinoid of the common bile duct was made. The patient was well with no evidence of recurrence 17 months postoperatively. The authors believe this is the 19th reported case of an extrahepatic bile duct carcinoid.  (+info)

Reexploration for periampullary carcinoma: resectability, perioperative results, pathology, and long-term outcome. (2/323)

OBJECTIVE: This single-institution experience retrospectively reviews the outcomes of patients undergoing reexploration for periampullary carcinoma at a high-volume center. SUMMARY BACKGROUND DATA: Many patients are referred to tertiary centers with periampullary carcinoma after their tumors were deemed unresectable at previous laparotomy. In carefully selected patients, tumor resection is often possible; however, the perioperative results and long-term outcome have not been well defined. METHODS: From November 1991 through December 1997, 78 patients who underwent previous exploratory laparotomy and/or palliative surgery for suspected periampullary carcinoma underwent reexploration. The operative outcome, resectability rate, pathology, and long-term survival rate were compared with 690 concurrent patients who had not undergone previous exploratory surgery. RESULTS: Fifty-two of the 78 patients (67%) undergoing reexploration underwent successful resection by pancreaticoduodenectomy; the remaining 26 patients (34%) were deemed to have unresectable disease. Compared with the 690 patients who had not undergone recent related surgery, the patients in the reoperative group were similar with respect to gender, race, and resectability rate but were significantly younger. The distribution of periampullary cancers by site in the reoperative group undergoing pancreaticoduodenectomy (n = 52) was 60%, 19%, 15%, and 6% for pancreatic, ampullary, distal bile duct, and duodenal tumors, respectively. These figures were similar to the 65%, 14%, 16% and 5% for resectable periampullary cancers found in the primary surgery group (n = 460). Intraoperative blood loss and transfusion requirements did not differ between the two groups. However, the mean operative time was 7.4 hours in the reoperative group, significantly longer than in the control group. On pathologic examination, reoperative patients had smaller tumors, and the percentage of patients with positive lymph nodes in the resection specimen was significantly less. The incidence of positive margins was similar between the two groups. Postoperative lengths of stay, complication rates, and perioperative mortality rates were not higher in reoperative patients. The long-term survival rate was similar between the two resected groups, with a median survival of 24 months in the reoperative group and 20 months in those without previous exploration. CONCLUSIONS: These data demonstrate that patients undergoing reoperation for periampullary carcinoma have similar resectability, perioperative morbidity and mortality, and long-term survival rates as patients undergoing initial exploration. The results suggest that selected patients considered to have unresectable disease at previous surgery should undergo restaging and reexploration at specialized high-volume centers.  (+info)

Prognostic value of MIB-1 index and DNA ploidy in resectable ampulla of Vater carcinoma. (3/323)

OBJECTIVE: To evaluate the prognostic value of the proliferative factors, MIB-1 index, DNA ploidy, and S-phase fraction, and further to determine the independent prognostic factors in ampulla of Vater carcinoma after pancreaticoduodenectomy. SUMMARY BACKGROUND DATA: Cell kinetics are important indicators of the biologic behavior of various human tumors, but only a few authors have reported the application of cell proliferative factors in ampulla of Vater carcinoma. METHODS: Patients undergoing pancreaticoduodenectomy for ampulla of Vater carcinoma were included. Proliferative factors, MIB-1 index, and DNA contents, measured by flow cytometry, were evaluated and compared with the conventional clinicopathologic factors. RESULTS: Ninety resectable ampulla of Vater carcinomas were included. By univariate analysis, MIB-1 index, DNA ploidy, S-phase fraction, stage, and lymph node status were significant prognostic factors. The 5-year survival rate was 40.7% for tumors with MIB-1 index < or =15% and 0% for those with MIB-1 index >15%. Diploid tumors had a significantly better prognosis than aneuploid. Outcomes of stage I and II tumors were more favorable than those of stage III and IV. After multivariate analysis, MIB-1 index, DNA ploidy, and stage remained as the independent prognostic factors. Among the three independent prognostic factors, MIB-1 index was the most powerful. CONCLUSIONS: Both MIB-1 index and DNA ploidy provide important prognostic value and potentially complement the conventional prognostic factors in resectable ampulla of Vater carcinoma. MIB-1 index is the most powerful independent prognostic factor.  (+info)

Pancreaticoduodenectomy with or without extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma: comparison of morbidity and mortality and short-term outcome. (4/323)

OBJECTIVE: This prospective, randomized, single-institution trial was designed to evaluate the end points of mortality, morbidity, and survival in patients undergoing standard versus radical (extended) pancreaticoduodenectomy (including distal gastrectomy and retroperitoneal lymphadenectomy). SUMMARY BACKGROUND DATA: Numerous retrospective reports and one prospective randomized trial have suggested that the performance of an extended lymphadenectomy in association with a pancreaticoduodenal resection may improve long-term survival for some patients with pancreatic and other periampullary adenocarcinomas. Many of these previously published studies can be criticized for their retrospective and nonrandomized designs, for the inclusion of nonconcurrent control groups, and for their small numbers. METHODS: Between April 1996 and December 1997, 114 patients with periampullary adenocarcinoma were enrolled in an ongoing, prospective, randomized trial at The Johns Hopkins Hospital. After intraoperative verification of completely resected periampullary adenocarcinoma, the patients were randomized to receive either a standard pancreaticoduodenectomy (removing only the peripancreatic lymph nodes en bloc with the specimen) or a radical pancreaticoduodenectomy (standard resection plus distal gastrectomy and retroperitoneal lymphadenectomy). All pathology specimens were reviewed and categorized. The postoperative morbidity, mortality, and short-term outcomes were examined. RESULTS: Of the 114 patients randomized, 56 underwent a standard pancreaticoduodenectomy and 58 a radical pancreaticoduodenectomy. The two groups were statistically similar with regard to age and gender, but there was a higher percentage of white patients in the radical group. All the patients in the radical group underwent distal gastric resection, whereas 86% of the patients in the standard group underwent pylorus preservation. The mean operative time in the radical group was 6.8 hours, compared with 6.2 hours in the standard group. There were no significant differences between the two groups with respect to the intraoperative blood loss, transfusion requirements, location of primary tumor, mean tumor size, positive lymph node status, or positive margin status. There were three deaths in the standard group and two in the radical group. The complication rates were 34% for the standard group and 40% for the radical group. Patients undergoing radical resection had a higher incidence of early delayed gastric emptying but had similar rates of other complications, such as pancreatic fistula, wound infection, intraabdominal abscess, and need for reoperation. The mean total number of lymph nodes resected was higher in the radical group. Of the 58 patients in the radical group, only 10% had metastatic carcinoma in the resected retroperitoneal lymph nodes, and none of those patients had the retroperitoneal nodes as the only site of lymph node involvement. The 1-year actuarial survival rate for patients surviving the immediate postoperative periods was 77% for the standard resection group and 83% for the radical resection group. CONCLUSIONS: These data demonstrate that radical pancreaticoduodenectomy (with the addition of a distal gastrectomy and extended retroperitoneal lymphadenectomy to a standard pancreaticoduodenectomy) can be performed with similar morbidity and mortality to standard pancreaticoduodenectomy. However, the survival data are not sufficiently mature and the numbers of patients enrolled are not adequate to allow firm conclusions to be drawn regarding survival benefit.  (+info)

Bilateral ovarian carcinoma metastatic from the ampulla of Vater: a rare Krukenberg tumor. (5/323)

Carcinoma of the ampulla of Vater is a relatively rare neoplasm and its longterm survival rate is considerably high. However, because of differences in tumor pathologic features and local invasiveness, a 5-year survival rate differ widely. We present a case of metastatic carcinoma of the ampulla of Vater presenting as a Krukenberg tumor in a 59-year-old woman. Eight months earlier, she had been diagnosed as well-differentiated adenocarcinoma of the ampulla of Vater. Abdominal examination revealed a hard mass with mild tenderness in the RLQ area. The laboratory findings were unremarkable except for mild anemia. CT scan of the abdomen revealed enlargement of both ovaries. An exploratory laparotomy disclosed bilateral ovarian masses, 18 x 12 x 8 cm and 8 x 5.5 x 4 cm in size, respectively. Histologic findings of the both ovarian masses were consistent with metastatic adenocarcinoma from the ampulla of Vater.  (+info)

Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. (6/323)

Peutz-Jeghers syndrome (PJS) is an autosomal-dominant disorder characterized by hamartomatous polyps in the gastrointestinal tract and by pigmented macules of the lips, buccal mucosa, and digits. Less appreciated is the fact that PJS also predisposes patients to an increased risk of gastrointestinal cancer, and pancreatic cancer has been reported in many PJS patients. It was recently shown that germline mutations of the STK11/LKB1 gene are responsible for PJS. We investigated the role of STK11/LKB1 in the development of pancreatic and biliary cancer in patients with and without the PJS. In a PJS patient having a germline splice site mutation in the STK11/LKB1 gene, sequencing analysis of an intestinal polyp and pancreatic cancer from this patient revealed loss of the wild-type allele of the STK11/LKB1 gene in the cancer. Inactivation of STK11/LKB1, by homozygous deletions or somatic sequence mutations coupled with loss of heterozygosity, was also demonstrated in 4-6% of 127 sporadic pancreatic and biliary adenocarcinomas. Our results demonstrate that germline and somatic genetic alterations of the STK11/LKB1 gene may play a causal role in carcinogenesis and that the same gene contributes to the development of both sporadic and familial forms of cancer.  (+info)

Adenoma of the ampulla of Vater: a genetic condition? (7/323)

The etiology of adenoma of the ampulla of Vater is not well understood. Previous authors reported the association of this neoplasm with polycystic kidney disease of two fraternal sisters. They concluded that these two conditions were somehow related. We describe a case of ampullary adenoma associated with polycystic kidney disease. This presentation raises again the question of a possible link between these two diseases.  (+info)

Brain metastases from adenoendocrine carcinoma of the common bile duct: a case report. (8/323)

A 68-year-old man with metastatic brain tumors from adenoendocrine carcinoma of the common bile duct is reported. A common bile duct tumor and a metastatic liver tumor had been resected 6 years and 3 years prior to admission, respectively. Microscopically they showed two components; moderately differentiated tubular adenocarcinoma and neuroendocrine carcinoma. He presented with headache and vomiting and MRI revealed two metastatic brain tumors. They were successfully resected and radiotherapy was carried out. Histological diagnosis of the metastatic brain tumors was neuroendocrine carcinoma, but carbohydrate antigen (CA)-19-9 and carcinoembryonic antigen (CEA)-immunoreactive cells were observed without glandular pattern. Immunohistochemically serotonin and pancreatic polypeptide were detected, but somatostatin was not. As the endocrine cells demonstrated in the normal extrahepatic bile ducts are only somatostatin-containing D cells, these cells are considered to originate as part of a metaplastic process. To our knowledge, this represents the second case of adenoendocrine carcinoma of the common bile duct.  (+info)

*List of MeSH codes (C04)

... biliary tract neoplasms MeSH C04.588.274.120.250 --- bile duct neoplasms MeSH C04.588.274.120.250.250 --- common bile duct ... nose neoplasms MeSH C04.588.149.721.656 --- orbital neoplasms MeSH C04.588.149.721.828 --- skull base neoplasms MeSH C04.588. ... anal gland neoplasms MeSH C04.588.274.476.411.445 --- duodenal neoplasms MeSH C04.588.274.476.411.501 --- ileal neoplasms MeSH ... femoral neoplasms MeSH C04.588.149.721 --- skull neoplasms MeSH C04.588.149.721.450 --- jaw neoplasms MeSH C04.588.149.721. ...

*List of MeSH codes (C06)

... common bile duct neoplasms MeSH C06.130.320.120 --- bile duct neoplasms MeSH C06.130.320.120.280 --- common bile duct neoplasms ... bile duct neoplasms MeSH C06.301.120.250.250 --- common bile duct neoplasms MeSH C06.301.120.401 --- gallbladder neoplasms MeSH ... File "2006 MeSH Trees".) MeSH C06.130.120.120 --- bile duct neoplasms MeSH C06.130.120.120.280 --- common bile duct neoplasms ... common bile duct diseases MeSH C06.130.120.250.098 --- biliary dyskinesia MeSH C06.130.120.250.098.800 --- sphincter of oddi ...

*Pancreatic serous cystadenoma

Serous cystic neoplasms can come to clinical attention in a variety of ways. The most common symptoms are very non-specific and ... a yellowing of the skin and eyes caused by obstruction of the bile duct), or weight loss. These signs and symptoms are not ... such as the intraductal papillary mucinous neoplasm and the mucinous cystic neoplasm), serous cystic neoplasms are almost ... mixed serous-endocrine neoplasm, and VHL-associated serous cystic neoplasm. This latter classification scheme is useful because ...

*Intraductal papillary mucinous neoplasm

... a yellowing of the skin and eyes caused by obstruction of the bile duct), weight loss, and acute pancreatitis. These signs and ... The most common symptoms include abdominal pain, nausea and vomiting. The most common signs patients have when they come to ... Intraductal papillary mucinous neoplasm (IPMN) is a type of tumor that can occur within the cells of the pancreatic duct. IPMN ... Pancreatic mucinous cystic neoplasm Pancreatic serous cystadenoma Solid pseudopapillary neoplasm "Intraductal Papillary ...

*Nucleoporin

... which inhibit p62 complexes have links to primary biliary cirrhosis which destroys the bile ducts of the liver. Decreases in ... The most common of these complexes is the p62 complex, which is an assembly composed of NUP62, NUP58, NUP54 and NUP45. Another ... is commonly found in precancerous dysplasias and malignant neoplasms. Each individual nucleoporin is named according to its ... Du Y, Wooten MC, Wooten MW (August 2009). "Oxidative damage to the promoter region of SQSTM1/p62 is common to neurodegenerative ...

*David B. Adams

Dixon, J. A.; Morgan, K. A.; Adams, D. B. (2009). "Management of common bile duct injury during partial gastrectomy". The ... Ellis, C. T.; Barbour, J. R.; Shary, T. M.; Adams, D. B. (2010). "Pancreatic cyst: Pseudocyst or neoplasm? Pitfalls in ... Theruvath, T. P.; Morgan, K. A.; Adams, D. B. (2010). "Mucinous cystic neoplasms of the pancreas: How much preoperative ...

*Gastrinoma

Most gastrinomas are found in the gastrinoma triangle; this is bound by the junction of cystic and common bile ducts, junction ... Pancreatic Endocrine Neoplasms webpage Surgery Questions on gastrinoma Gastrinoma Triangle. ...

*Cholangiocarcinoma

Distal cholangiocarcinomas (those arising from the common bile duct) are generally treated surgically with a Whipple procedure ... Cholangiocarcinoma is a relatively rare neoplasm that is classified as an adenocarcinoma (a cancer that forms glands or ... Patient information on extrahepatic bile duct tumors, from the National Cancer Institute. Cancer.Net: Bile Duct Cancer The ... Tumors occurring in the bile ducts within the liver are referred to as intrahepatic, those occurring in the ducts outside the ...

*Liver cancer

Less common types include mucinous cystic neoplasm and intraductal papillary biliary neoplasm. The diagnosis may be supported ... Liver cancer can also form from other structures within the liver such as the bile duct, blood vessels and immune cells. Cancer ... The majority of cholangiocarcimas occur in the hilar region of the liver, and often present as bile duct obstruction. If the ... "SEER Stat Fact Sheets: Liver and Intrahepatic Bile Duct Cancer". NCI. Archived from the original on 2017-07-28. Retrieved 2016 ...

*List of cancer types

... gastrointestinal Colon cancer Extrahepatic bile duct cancer Gallbladder cancer Gastric (stomach) cancer Gastrointestinal ... For some common cancers, the English organ name is used. For example, the most common type of breast cancer is called ductal ... Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ... Blastomas are more common in children than in older adults. Cancers are usually named using -carcinoma, -sarcoma or -blastoma ...

*Pancreatic mass

... an abnormal yellowing of the skin and eyes often caused by blockage of the bile ducts) are more likely to have a pancreatic ... The most common include CT scan (computerized axial tomography), magnetic resonance imaging (MRI), positron emission tomography ... Some cysts are cancerous, and others, such as the intraductal papillary mucinous neoplasm (IPMN) are potentially precancerous. ... MRI is a great method to visualize the pancreatic ducts, PET scanning can reveal the metabolic activity of a tumor, EUS ...

*Sarcoma botryoides

... common bile duct, urinary bladder of infants and young children or the vagina in females, typically younger than age 8. The ... Neoplasms of the Vulva and Vagina. in Holland-Frei Cancer Medicine - 6th Ed. Kufe, DW et al. editors. BC Decker Inc., Hamilton ... For botryoid rhabdomyosarcoma of the vagina, the most common clinical finding is vaginal bleeding but vaginal bleeding is not ...

*Hepatotoxicity

Injury to hepatocyte and bile duct cells lead to accumulation of bile acid inside the liver. This promotes further liver damage ... Oral contraceptives Neoplasm Neoplasms have been described with prolonged exposure to some medications or toxins. ... Zonal Necrosis This is the most common type of drug-induced liver cell necrosis where the injury is largely confined to a ... it can produce features similar to primary biliary cirrhosis due to progressive destruction of small bile ducts (Vanishing duct ...

*Pancreatic cancer

This results when a cancer in the head of the pancreas obstructs the common bile duct as it runs through the pancreas. ... Pancreatic mucinous cystic neoplasms are a broad group of pancreas tumors that have varying malignant potential. They are being ... Liver function tests can show a combination of results indicative of bile duct obstruction (raised conjugated bilirubin, γ- ... Pancreatic cancer is the fifth most common cause of death from cancer in the United Kingdom, and the fourth most common in the ...

*Neoplasm

... are common precursors to development of the disordered and improperly proliferating clone of tissue in a malignant neoplasm. ... Bile acids, at high levels in the colons of humans eating a high fat diet, also cause DNA damage and contribute to colon cancer ... Discrete localized enlargements of normal structures (ureters, blood vessels, intrahepatic or extrahepatic biliary ducts, ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ...

*Somatic evolution in cancer

... bile duct cancer, pancreatic cancer, small intestine cancer and colon cancer. In the colon, a field defect probably arises by ... which may be benign neoplasms) or else a malignant neoplasm (cancer). These neoplasms are also indicated, in the diagram below ... One common feature of neoplastic progression is the expansion of a clone with a genetic or epigenetic alteration. This may be a ... A common cytotoxic chemotherapy used in a variety of cancers, 5-fluorouracil (5-FU), targets the TYMS pathway and resistance ...

*Pseudomyxoma peritonei

Other primary sites that have been reported include colon, rectum, stomach, gallbladder, bile ducts, small intestine, urinary ... For example, neoplasms characterized by high-grade features, invasive glands and or signet ring cells, are termed ... Since the mucus tends to pool at the bottom of the abdominal cavity, it is common to remove the ovaries, fallopian tubes, ... It is slightly more common in women than men (male:female ratio = 9:11[citation needed]). The median age at presentation is ...

*Index of oncology articles

... common bile duct - comorbidity - compassionate use trial - complementary and alternative medicine - complete blood count (CBC ... neoplasm - nephrotomogram - nephrotoxic - nephroureterectomy - nerve block - nerve grafting - nerve-sparing radical ... bile duct - biliary - bilirubin - binding agent - bioavailable - biochanin A - biochemical reactions - biological response ... intrahepatic bile ducts - intrahepatic infusion - intralesional - intraluminal intubation and dilation - Intramuscular ...

*Small intestine

It also receives bile and pancreatic juice through the pancreatic duct, controlled by the sphincter of Oddi. The primary ... A few of them are listed below, some of which are common, with up to 10% of people being affected at some time in their lives, ... Neoplasms (cancers) Adenocarcinoma Carcinoid Gastrointestinal stromal tumor (GIST) Lymphoma Sarcoma Leiomyoma Metastatic tumors ... Pancreatic lipase works with the help of the salts from the bile secreted by the liver and stored in the gall bladder. Bile ...

*Thyroid

The most common neoplasm affecting the thyroid gland is a benign adenoma, usually presenting as a painless mass in the neck. ... A persistent thyroglossal duct is the most common clinically significant congenital disorder of the thyroid gland. A persistent ... perhaps by increasing the rate of secretion of cholesterol in bile. Cardiovascular. The hormones increase the rate and strength ... Hashimoto's is more common in females than males, much more common after the age of 60, and has known genetic risk factors. ...

*Pancreas

As the duodenum rotates to the right, it carries with it the ventral pancreatic bud and common bile duct. Upon reaching its ... Patil TB, Shrikhande SV, Kanhere HA, Saoji RR, Ramadwar MR, Shukla PJ (2006). "Solid pseudopapillary neoplasm of the pancreas: ... The intercalated ducts drain into larger ducts within the lobule, and finally interlobular ducts. The ducts are lined by a ... The exocrine part has two main ducts, the main pancreatic duct and the accessory pancreatic duct. These drain enzymes through ...

*International Classification of Diseases for Oncology

Bile duct carcinoma Bile duct adenocarcinoma M8161/0 (C22.1, C24.0) M8161/3 Bile duct cystadenocarcinoma (C22.1, C24.0) M8162/3 ... NOS M8000/6 Neoplasm, metastatic Neoplasm, metastatic Tumor, metastatic Tumor, secondary Tumor embolus M8000/9 Neoplasm, ... Pro-B ALL Common precursor B ALL Pre-B ALL Pre-pre-B ALL Common ALL c-ALL M9837/3 Precursor T lymphoblastic leukemia (see also ... Infiltrating duct adenocarcinoma Duct adenocarcinoma, NOS Duct carcinoma, NOS Duct cell carcinoma Ductal carcinoma, NOS M8501/2 ...
AIM: To investigate endoscopic ultrasound (EUS) for predicting depth of mucosal invasion and to analyze outcomes following endoscopic and transduodenal resection. METHODS: Records of 111 patients seen at our institution from November 1999 to July 2011 with the postoperative pathological diagnosis of benign ampullary and duodenal adenomas were reviewed. Records of patients who underwent preoperative EUS for diagnostic purposes were identified. The accuracy of EUS in predicting the absence of muscular invasion was assessed by comparing EUS reports to the final surgical pathological results. In addition, the incidence of the post-operative complications over a period of 30 d and the subsequent long-term outcome (recurrence) over a period of 30 mo associated with endoscopic and transduodenal surgical resection was recorded, compared and analyzed. RESULTS: Among 111 patients with benign ampullary and duodenal adenomas, 47 underwent preoperative EUS for 29 peri-ampullary lesions and 18 duodenal ...
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Periampullary cancers encompass a mixture of cancers but in general are separated into four subtypes: cancer in the head of the pancreas, distal bile duct cancer, true ampullary cancer, and duodenal cancer. These cancers arise in the vicinity of the ampulla of Vater and are differentiated by their histologic origins (pancreatic, distal bile duct, ampulla of Vater, or duodenum). While pancreatic adenocarcinoma makes up the majority of resected periampullary cancers at 62%, ampullary cancer accounts for 19%, distal bile duct cancer 12%, and duodenal cancer 7% of resected periampullary cancers.1 Although preoperative assessment with imaging and biopsy can distinguish one subtype from the other, often times the tumor origin may be undetermined preoperatively. Moreover, duodenal cancer in the periampullary region as well as intestinal-type ampullary cancer behave in a similar fashion, whereas distal bile duct cancer and pancreaticobiliary-type ampullary cancer behave similar to one another. While 56% ...
TY - JOUR. T1 - Reexploration for periampullary carcinoma. T2 - Resectability, perioperative results, pathology, and long-term outcome. AU - Sohn, Taylor A.. AU - Lillemoe, Keith D.. AU - Cameron, John L.. AU - Pitt, Henry A.. AU - Huang, John J.. AU - Hruban, Ralph H.. AU - Yeo, Charles J.. PY - 1999/3. Y1 - 1999/3. N2 - Objective: This single-institution experience retrospectively reviews the outcomes of patients undergoing reexploration for periampullary carcinoma at a high-volume center. Summary Background Data: Many patients are referred to tertiary centers with periampullary carcinoma after their tumors were deemed unresectable at previous laparotomy. In carefully selected patients, tumor resection is often possible; however, the perioperative results and long-term outcome have not been well defined. Methods: From November 1991 through December 1997, 78 patients who underwent previous exploratory laparotomy and/or palliative surgery for suspected periampullary carcinoma underwent ...
The term ampullary tumour generally refers to either benign or malignant neoplasms that arise from the glandular epithelium of the ampulla of Vater, including 1: ampullary adenoma (adenoma of ampulla of Vater) ampullary carcinoma (carcinoma of ...
Aims: Pancreatic adenocarcinoma is an aggressive gastrointestinal malignancy with only a few long-term survivors even after radical surgery. Patients with ampullary cancer have a better prognosis but adjuvant therapy needs further improvement. Epithelial cell adhesion molecule (Ep-CAM) is strongly expressed in a variety of epithelial cancers and represents a promising target for immunological tumour therapy. Thus, the aim of this study was to investigate Ep-CAM expression and its potential prognostic impact in pancreatic and ampullary carcinomas.. Methods: Ep-CAM expression was investigated retrospectively by immunohistochemistry in paraffin-embedded primary tumour tissue samples from a series of consecutive patients with pancreatic (n = 153) and ampullary cancer (n = 34).. Results: Ep-CAM overexpression was observed in 85 of 153 pancreatic cancer specimens (56%) and in 29 of 34 ampullary cancer samples (85%). Overall, Ep-CAM failed to be an independent prognostic marker. However, subgroup ...
Ampullary cancer is a malignant tumor that arises from the Ampulla of Vater, the last centimeter of the common bile duct as it passes through the duodenum, the first
TY - JOUR. T1 - How many lymph nodes properly stage a periampullary malignancy?. AU - Gutierrez, Juan C.. AU - Franceschi, Dido. AU - Koniaris, Leonidas G.. PY - 2008/1/1. Y1 - 2008/1/1. N2 - The impact of lymphadenectomy in prognosis and staging in periampullary malignancies remains largely undefined. We examined all pancreaticoduodenectomies for periampullary carcinomas in the SEER cancer registry from 1993 through 2003. Overall, 5465 pancreaticoduodenectomies for nonmetastatic periampullary carcinomas were identified. The cohort was comprised of 62.5% pancreatic, 18.9% ampullary, 11.6% distal bile duct, and 7.0% duodenal cancers. A linear association between the number of lymph nodes (LNs) examined and overall survival was observed overall and for pancreas and ampullary cancers for node-negative (N0) disease. Median survival for all patients with localized, N0 disease improved from 24 to 31 months, with sampling of a minimum of 10 LNs, whereas 2 and 5-year survival improved from 52 and 29%, ...
When Adrienne Skinner was diagnosed with ampullary cancer, a rare gastrointestinal tumor, in early 2013, it didnt come as a complete surprise. For nearly a decade, she had known her genes were not in her favor. What she didnt know was that her genes ...
Victor Maciel, MD. St. Vincent Hospital. Background: Ampullectomy is mostly performed for periampullary malignancies, however, some benign disease may benefit from ampullectomy too. Transduodenal ampullectomy requires a precise dissection and complex reconstruction. Our group has been performing robotic ampullectomies for sphincter of Oddi dyskinesia (SOD) since 2005 with good results. The introduction of robotic techniques to our practice opened the possibility of performing this technically challenging operation with a minimally invasive approach and the added benefit of articulating instruments which -we believe- result in a better intra-abdominal suturing. We studied all consecutive cases of robotic ampullectomies for SOD performed since 2005 to date (n=13). Demographics, intraoperative and postoperative complications, length of stay, blood loss and operative times were recorded. Our main goal was to discuss the robotic ampullectomy technique and to evaluate the early results of this ...
Recently, immunohistochemistry-based classifications of ampullary carcinomas have been proposed (Ang and colleagues [PMID: 24832159]; Chang and colleagues [PMID: 23439753]). In this study, the prognostic value of Ang/Chang panel markers (CK20, MUC1, MUC2, CDX2) as well as other markers (CK7, MUC5AC, and MUC6) were tested on full-faced sections of 136 ampullary carcinoma resections with substantial (,5 mm) invasion. Immunohistochemistry was correlated with both histologic classification (intestinal [INT], pancreatobiliary [PB], or nontubular based on ≥3/5 observer agreement) and clinical outcome. No prognostic correlation was found with MUC1, CDX2, MUC2 or CK20 despite testing with different quantitative cutoffs. CK7 and CK20 were nonspecific. Ang classification had reasonable correlation with histologic subclassification of tubular cases as INT versus PB with high specificity but low sensitivity and ambiguous category was large (29%) and included also some classical cases. Prognostically, Ang ...
Periampullary tumours are those that arise within 2 cm of the ampulla of Vater in the duodenum. Pathology Tumours that fall under this group include four main types of tumours 1,4: pancreatic head/uncinate process tumours: includes pancreatic ...
Staerkle RF, Soll C, Vuille-dit-Bille RN, Samra J, Puhan MA, Breitenstein S. Extended lymph node resection versus standard resection for pancreatic and peri-ampullary adenocarcinoma. Cochrane Database of Systematic Reviews 2015, Issue 2. Art. No.: CD011490. DOI: 10.1002/14651858. ...
A 76-year-old female with Ampulla of Vater carcinoma.A. The five-day follow-up plain film after stent insertion shows good stent positioning on the air-biliary
Carcinoma of the ampulla of Vater is a malignant tumor arising in the last centimeter of the common bile duct, where it passes through the wall of the duodenum and ampullary papilla. The pancreatic duct (of Wirsung) and common bile duct merge and exit by way of the ampulla into the duodenum.
G. Ghidirim(1), I. Misin(1), V. Istrate(1), S. Cazacu(2) (1)Department of Surgery N. Anestiadi , Hepato- Bilio-Pancreatic Surgery Laboratory, University of Medicine and Pharmacy
There are no specific blood tests for the diagnosis of pancreatic carcinoma. Abnormal liver function tests cannot reliably distinguish biliary obstruction (of any cause) from hepatic metastases. The most useful initial investigation seems to be abdominal ultrasonography which can identify the pancreatic tumour, as well as dilated bile ducts, and will save considerable time and inconvenience if liver metastases are identified. The reported sensitivity of ultrasonography in the detection of pancreatic carcinoma is as high at 80-95%.51-53 The technique however, becomes less sensitive in evaluating the body and tail and provides less accurate staging information than other modalities, such as CT.54,55 Technical difficulties with bowel gas compromise interpretation in 20-25% of subjects,56 and interobserver variation continues to be a problem.53 Improvements in ultrasound technology, with inclusion of colour Doppler, may improve staging accuracy, particularly with respect to vascular ...
To assess the feasibility of administering induction chemotherapy with gemcitabine and docetaxel followed by concurrent radiation and continuous infusio
Cancer of the ampulla of Vater must be differentiated from cancer of the head of the pancreas. Prognosis and potential therapeutic intervention are different. 87% of patients with carcinoma of the ampulla and 47% of those with a malignancy of the duodenum have a potentially operable tumour compared with only 22% of patients with tumours arising from the head of the pancreas [2, 12]. Therefore a noninvasive accurate technique for detection and staging is mandatory for these patients.. The endoscopic appearance of the papilla was abnormal in most of our patients. However the distinction between an impacted stone, a benign tumour or a malignancy is not always feasible. ERCP with endoscopic sphincterotomy was a helpful diagnostic procedure in cases of intraampullary tumors with a protruding papilla. In 3 cases of our patients a polypoid mass was evident only after sphincterotomy. However, ERCP is an invasive procedure with a considerable morbidity.. Moreover, endoscopic biopsies do not always allow ...
Continuing part two of our mini-series on colorectal cancer, today we move from the big scale Immunoscore study to small subsets of disease that are looking interesting in several ways.. For years, advanced colorectal cancer has been dominated by chemotherapy (FOLFOX or FOLFIRI) with and without targeted therapies (VEGF and EGFR antibodies), with very little new to talk about. Part of the challenge here is how do you add something the existing standard of care and move the needle significantly. In front-line, for example, the OS is already out 2-plus years, so these are long and risky trials to undertake. Not surpisingly, many companies have sought to evaluate their agents in tumour types where they consider the risk of development to be lower.. Unless… we can find creative approaches that turn the paradigm on its head and identify a clearly defined niche that can be carved out separately from allcomers.. This is where were at now - identifying subsets that might respond exquisitely to novel ...
• One hundred four consecutive patients who underwent radical resection for ampullary cancer between 1965 and 1989 were retrospectively reviewed. Frequent clini
... - Ampulla of Vater Carcinoma Adenocarcinoma Author: Hanni Gulwani, M.D. (see Authors page) Revised: 13 August , last major update August May Pages Full text
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The first localized resection of an ampullary lesion was performed transduodenally by Halsted in 1899. Since Halsteds time, technological advancements have enhanced the array of tools at the disposal of the modern surgeon.
We found sensitivity for the ascertainment of pancreatic and periampullary cancer cases from the hospital data of 87.5% for the 2005-2009 period. The accuracy of hospital coding varied by tumour primary site and histology, with higher sensitivity of case ascertainment for pancreatic (88.6%) and duodenal cancers (87.1%) compared with extrahepatic bile duct and ampullary cancers (78.8%) and with lower sensitivity for extrahepatic cholangiocarcinomas (67.9%). Misclassification of pancreatic and periampullary cancers in the hospital data was often to closely related sites, for example, intrahepatic bile duct carcinoma, or to less specific sites such as cancers of ill-defined or unspecified primary sites. Whereas hospital coders might only have information from a particular admission available, coders at a cancer registry often have multiple sources of information from diagnostic procedures and treatment which can enable more accurate coding of tumour characteristics.. Several aspects of the coverage ...
Ampullary cancer, or ampullary carcinoma, is a life-threatening cancer that forms in a body part called the ampulla of Vater in the duodenum, where the pancreatic and bile ducts release their secretions into the intestines.
Looking for online definition of adenomyoma in the Medical Dictionary? adenomyoma explanation free. What is adenomyoma? Meaning of adenomyoma medical term. What does adenomyoma mean?
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TY - CONF. T1 - Laparoscopic ultrasonography. T2 - An adjunct to the stagingof gastric cancer?. AU - Mortensen, Michael Bau. AU - Madsen, M. R.. AU - Hovendal, Claus Peter. PY - 1994/5/25. Y1 - 1994/5/25. M3 - Poster. ER - ...
PubMed journal article Carcinoma of the ampulla of Vater: comparative histologic/immunohistochemical classification and follow-u were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
Cancer Therapy Advisor provides gastroenterology and hepatology professionals with the latest gastroenterology and hepatology conditions, procedures and guides for different surgical and non surgical conditions. Visit often for updates and new information.
Purpose: MEK inhibition has clinical activity against biliary cancers, and might therefore be successfully combined with gemcitabine; one of the most active chemotherapy agents for these cancers. As gemcitabine is active in S-phase, and the ERK pathway has a major role driving cell cycle progression, concurrent use of a MEK inhibitor could potentially antagonize the effect of gemcitabine. We therefore tested the sequence dependence of the combination of gemcitabine and the MEK inhibitor AZD6244 using a series of biliary cancer models. Experimental Design: Primary xenografts were established from patients with gallbladder and distal bile duct cancer, and grown in SCID mice at the subcutaneous site. Plasma and tumor drug levels, and the time course for recovery of ERK signaling and S-phase were measured in tumor-bearing mice treated for 48hr with AZD6244 and then monitored for 48hr off treatment. Based on these results, two different treatment schedules combining AZD6244 with gemcitabine were ...
OBJECTIVES: To propose a therapeutic approach and follow-up of patients with atypical polypoid adenomyoma (APA) wishing to remain fertile. PATIENTS AND METHOD: We are presenting a retrospective study of eight APA cases. RESULTS: Two patients immediat
Preliminary Efficacy: Control or Regression of Injected Tumors by Measurement of Length, Width and Height (in centimeters) Radio-graphically Using Computer Tomography or Magnetic Resonance Imaging to Calculate Tumor Volumes (cubic centimeters) Over Time ...
At 1:08PM CST on Thursday, June 12, 2014, the world lost one of its kindest, gentlest, and most generous souls at the age of 66 to a rare form of cancer that originally attacked his Ampulla of Vater, a small pathway located in the pancreas. William J. Bezdek was beloved and admired by all who…
IMAI Yasuo , TSURUTANI Naomi , ODA Hideaki , NAKATSURU Yoko , INOUE Tohru , ISHIKAWA Takatoshi Japanese journal of cancer research : gann 88(10), 941-946, 1997-10-31 医中誌Web 参考文献26件 被引用文献2件 ...
Preoperative biliary drainage methods include percutaneous transhepatic biliary drainage (PTBD), endoscopic nasobiliary drainage (ENBD), and endoscopic retrograde biliary drainage (ERBD). Endoscopic biliary drainages often induce peritumoral inflammation and it increase difficulties in determining a proper resection margin. The purpose of this study is to compare the clinicopathological outcomes according to the methods of preoperative biliary drainage in periampullary cancers causing obstructive jaundice, and to find out a proper biliary drainage method ...
The major duodenal papilla is an opening of the Common bile duct and Pancreatic duct into the duodenum. The major duodenal papilla is, in most people, the primary mechanism for the secretion of bile and other enzymes that facilitate digestion. The major duodenal papilla is situated in the second part of the duodenum, 7-10 cm from the pylorus, at the level of the second or third lumbar vertebrae. It is surrounded by the sphincter of Oddi, and receives a mixture of pancreatic enzymes and bile from the Ampulla of Vater, which drains both the pancreatic duct and biliary system. The junction between the foregut and midgut occurs directly below the major duodenal papilla. The major duodenal papilla is seen from the duodenum as lying within a mucosal fold. The minor duodenal papilla is situated 2cm proximal. The major duodenal papilla is occasionally found in the third part of the duodenum, the level of the vertebrae may be L2-3, and in about 10% of people, it may not receive bile. Additionally, in a ...
Looking for online definition of ampullary type of renal pelvis in the Medical Dictionary? ampullary type of renal pelvis explanation free. What is ampullary type of renal pelvis? Meaning of ampullary type of renal pelvis medical term. What does ampullary type of renal pelvis mean?
Comparisons will be made of the primary endpoints of both intervention groups for all randomized patients who underwent surgery involving the pp-Whipple procedure. Patients will be analysed as randomized applying the ITT principle [18]. In addition, a per-protocol analysis will be performed, including patients who are strictly treated according to the study protocol.. The outcome measures of the primary endpoint will be tested confirmatory applying an analysis of covariance with treatment as factor and age and BMI as continuous covariates.. Secondary endpoints will be analysed in a descriptive manner. Graphically methods will be used by means of box- and scatter- plots. For all continuous secondary endpoints a t-test will be applied, possible differences of categorical secondary endpoints will be analysed using chi-square tests. All p-values will be used as descriptive statistics only without any confirmatory value.. The secondary endpoint Quality of Life (EORTC QLQ-C30, EORTC QLQ PAN26) will be ...
The histopathology of 12 patients with adenoma of the ampulla of Vater was examined to trace the adenoma-carcinoma sequence of the ampulla of Vater. Immunohistochemistry for carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 was also performed. Four large adenomas with mild dysplasia also had foci of moderate dysplasia while another one contained foci of severe dysplasia (intramucosal carcinoma). Immunohistochemically, adenomas of mild to moderate dysplasia had either linear CEA and CA19-9 immunoreactants at the apical portions, or fine granular immunoreactants in the cytoplasm of adenoma cells. In addition, adenomas of severe dysplasia (intramucosal carcinoma) showed a more diffuse or dense immunoreactivity for these two substances in the cytoplasm. These results are consistent with the adenoma-carcinoma sequence for the ampulla of Vater. The immunohistochemistry for CEA and CA19-9 was representative of the degree of dysplasia in the adenoma cells, but the relationship was not ...
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Disease Ontology : 12 A cervix carcinoma that has material basis in neuroendocrine tissue and is characerized by a diffuse, organoid, trabecular, or cord-like pattern of neoplastic cells with abundant cytoplasm, large nuclei, prominent nucleoli, and a high mitotic rate ...
Background Delayed gastric emptying (DGE) is a major postoperative problem after pylorus-preserving pancreatoduodenectomy (PpPD) and sometimes causes reflux esophagitis. demonstration A 63-year-old GW843682X guy underwent Kid and PpPD reconstruction with Braun anastomosis for lower bile duct carcinoma. Fourteen days after medical procedures DGE happened and a 10?cm lengthy stricture from middle esophagus to cardia developed one . 5 month after medical procedures regardless of the administration of antacids. Balloon dilation was performed but occurred. It was retrieved with traditional treatment. Actually the administration of the proton GW843682X pump inhibitor (PPI) for about five mouths didnt improve esophageal stricture. Simultaneous 24-h bilirubin and pH monitoring verified that affected person was resistant to PPI. We performed middle-lower esophagectomy with total gastrectomy to avoid gastric acidity from injuring reconstructed body organ and remnant esophagus through the right ...
Background: Advances in surgical technique and increase in surgeons experience have made total laparoscopic pancreatoduodenectomy (TLPD) a subs..
CMS recognized the importance of appropriate use criteria for diagnostic imaging by physicians who order and furnish the services as a qualifying high-weighted .diagnostic imaging services cpt code listing - 2015 cpt code description cpt code description cpt code description 78016 nm, thyroid ca mets imaging, c/ addtnl .Special Article.Abnormalities of the Distal Common Bile Duct and Ampulla: Diagnostic Approach and Differential Diagnosis Using Multiplanar Reformations and 3D ImagingSCOT-HEART (Scottish COmputed Tomography of the HEART) and PROMISE (PROspective Multicenter Imaging Study for Evaluation of chest pain) represent the 2Services at Diagnostic Centers of America is a state-of-the-art diagnostic imaging center which provides radiology excellence. DCA provides the highest quality images .Diagnostic Imaging Chest 2nd Edition.pdf Free Download Here MEDICAL RADIOLOGY Diagnostic ImagingDownload and Read Diagnostic Imaging Chest 2nd Edition Diagnostic Imaging Chest 2nd Edition What do you do ...
The Whipple procedure (pancreatoduodenectomy) is the most common operation performed for pancreatic cancer and may be used to treat other cancers such as small bowel cancer. Surgeons remove the head of the pancreas, most of the duodenum (a part of the small intestine), a portion of the bile duct and sometimes a portion of the stomach. After the pancreatoduodenectomy, the surgeon reconstructs the digestive tract. (www.mayoclinic.org ...
A margin distance analysis of the impact of adjuvant chemoradiation on survival after pancreatoduodenectomy for pancreatic adenocarcinoma
PubMed journal article Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic adenocarcinoma were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
Define common bile duct. common bile duct synonyms, common bile duct pronunciation, common bile duct translation, English dictionary definition of common bile duct. n. The duct formed by the union of the cystic duct and the hepatic duct that carries bile from the liver and the gallbladder to the duodenum. Noun 1.
The minor duodenal papilla is the opening of the accessory pancreatic duct into the descending second section of the duodenum. The minor duodenal papilla is contained within the second part of the duodenum. It is situated 2 cm proximal to the major duodenal papilla, and thus 5-8 cm from the opening of the pylorus. The gastroduodenal artery lies posterior. The minor duodenal papilla may or may not contain a functioning sphincter and patent duct. When present, the sphincter is known as the sphincter of Helly, and the duct the accessory pancreatic duct of Santorini. In 10% of people, the minor duodenal papilla is the prime duct for drainage of the pancreas, although in others it may not be present at all. Pain from the region will be referred to the epigastric region of the abdomen due to its associated dermatomes.[citation needed] The duct is an embryological remnant, however in a small majority of people drains the pancreas. The minor duodenal papilla represents the remnants of the opening of the ...
During the one-year period, a total of 181 hospitalized patients with serum ALP level over 1000 IU/L were identified. They were 102 male and 96 female patients with ages ranging from 21 to 90 years old (mean age 49.4 ± 16.1 years). The ALP levels ranged from 1,001 to 3,067 IU/L.. The most common diagnosis in patients with high ALP in our series was malignant biliary obstruction. This was found in 58 patients, 48 of whom were cases with cholangicocarcinoma (CCA). Of the remaining 10, three were with pancreatic cancer, one with ampullary cancer, one with metastatic cancer, and five with periampullary cancer. The ALP levels ranged from 1,005 to 3,067 IU/L (average 1,869.8 ± 325.3 IU/L). In addition, benign duct obstruction from choledocholithiasis was found in another 14 patients, six of which cases were complicated by ascending cholangitis. The ALP level in this group ranged from 1,001 to 2,864 IU/L (average 1,498.3 ± 541.2 IU/L). Comparing these two groups, the mean ALP levels in the malignant ...
Two mutually exclusive genomic LCNEC subtypes have been identified by molecular studies: one shows co-mutated TP53 and RB1, which is similar to SCLC, and the STK11/KEAP1 subtype with predominantly RB1 wild-type that is similar to NSCLC.. Reviewing clinical data and tumour specimens of 232 patients in the Netherlands Cancer Registry and Pathology Registry from 2003 to 2012, this retrospective analysis identified 148 patients who had been diagnosed with LCNEC. Of these, samples from all patients receiving first-line chemotherapy for panel-consensus diagnosed LCNEC were included for next-generation sequencing (NGS) for the TP53, RB1, STK11, and KEAP1 genes. RB1 (pRB1, 13A10) was analysed by immunohistochemistry, with samples having an H-score of ≥50 considered positive.. The results of the NGS and pRB1 were correlated with overall survival (OS) and progression-free survival (PFS) by Kaplan Meier plots and Log-rank test.. Quality control of the samples determined that 79 samples were sufficient ...
Using enrichment analysis for Gene Ontology Biological Function we see that the genes/proteins with up-regulated PTMs and expression levels are associated with RNA processing, RNA splicing and, gene expression. Re-running the analysis for the sub-cluster of very highly regulated PTMS/genes (the large cluster in the middle) reveals enrichment for neuronal functions including: neuron projection, axon guidance, and neuron morphology. Enrichment for genes that are up-regulated in disease (using the Disease Perturbations from GEO Up library) shows enrichment for neuronal related cancers including: oligodendroglioma, multiple sclerosis, astrocytoma, and large cell neuroendocrine carcinoma. Finally, enrichment using the MGI Mammalian Phenotype library shows enrichment for genes that cause neuronal abnormalities in mice after knockdown including: abnormal neuron morphology, abnormal brain morphology, abnormal spinal cord morphology, and abnormal nervous system. Collectively, these results indicate that ...
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Oncology, Gastroenterology and Hepatology Reports (OGH Reports) [ISSN:Print -2278-8921, Online - 2348-3113] aims to explore the areas of Cancer research and gastrointestinal tract including the liver. The journal is envisioned as a platform for basic and translational researchers, clinicians and students to publish their original research, review articles and case reports ...
There are 8 nine-letter words containing 2A, P, U and Y: AMPULLARY AUTOPHAGY CAPSULARY ... SCAPULARY UNPAYABLE UPSADAISY. Every word on this site is valid scrabble words. Build other lists, that start with or end with letters of your choice.
Hofemeister J, Conrad B, Adler B, Hofemeister B, Feesche J, Kucheryava N, Steinborn G, Franke P, Grammel N, Zwintscher A, Leenders F, Hitzeroth G, Vater J, Molecular genetics and genomics , 2004, Nov,272(4):363-78 ...
The examination of brush cytology specimens has become an established diagnostic technique in the investigation of patients with suspected pancreatic, bile duct, gallbladder, and ampullary tumours. We have reviewed 448 consecutive brush samples obtained from 406 patients and correlated the findings with pathological and clinical outcomes. To our knowledge, this is the largest series of pancreatico-biliary brush cytology specimens yet reported.. As with previous studies, we found that the brush cytology technique produced cellular samples of good quality in most instances. Only 26 of 489 (5.3%) specimens were considered inadequate for diagnosis. Seven patients with initial unsatisfactory cytology samples underwent repeat endoscopy and an adequate specimen was obtained in six cases. The number of unsatisfactory specimens has not been specifically noted in many previous studies although rates of 0-6% were documented in three series.9, 11, 18 There was no clear correlation between unsatisfactory ...
This video demonstrates an end-to-side duct-to-mucosa pancreaticojejunostomy as part of a pancreaticoduodenectomy to resect a pancreatic head neoplasm. The patient is a 69 year-old female who experienced months of right upper quadrant abdominal pain and had labs consistent with biliary obstruction. Work-up with endoscopic retrograde cholangiopancreatography (ERCP) identified an ampullary mass that was biopsied and returned as ampullary carcinoma. DOI: http://dx.doi.org/10.17797/dyb8dqxxnr Editor Recruited By: Jeffrey B. Matthews, MD
MAZZA, Osear et al. Duodenopancreatectomía totalmente laparoscópica: Consideraciones técnicas y aplicabilidad inicial en un centro de alto volumen de cirugía pancreática. Rev. argent. cir. [online]. 2012, vol.102, n.2, pp. 62-68. ISSN 2250-639X .. Background: pancreatoduodenectomy is the treatment of choice for periampullary tumors. The first laparoscopic Whipple was performed by Gagner in 1994. However, the extensión of the dissection, the need to perform múltiple anastomoses in reconstructive phase and the length of the procedure were the main reasons that discouraged surgeons. However in recent years the laparoscopic Whipple procedure has emerged as a therapeutic alternative with encouraging results in selected patients. Aim: present the initial experience with laparoscopic Whipple procedure and the technical aspeets of the approach. Setting: hepatobiliopancreatic surgery sector of the Hospital Italiano de Buenos Aires. Design: prospective, observational. Population: 28 patients ...
Ampulla of Vater Also known as the hepatopancreatic ampulla, the ampulla of Vater is formed by the union of the common bile duct and the pancreatic duct when they enter the intestine. Amylase An enzyme that breaks down starch into sugar (polysaccharides). Amylase is present in human saliva, where it begins the chemical process of digestion. Benign Refers to tumors that do not spread to other organs or sites. Bile
Vater乳頭遠位十二指腸病変に対するPancreas-sparing Distal Duodenectomy―3例の経験―Vater乳頭遠位十二指腸病変に対するPancreas-sparing Distal Duodenectomy―3例の経験―AN00161368 ...
Contrast enhanced computed tomography of abdomen of the patient showing a periampullary mass (yellow arrow) with ascites (red arrow) and dilated intrahepatic bi
Bile duct cancer. Coloured angiogram (X-ray) of a patients common bile duct (dark red, centre right) that has been blocked by cancer. The cancer (not seen) has caused a narrowing, or stricture, of the duct. A stent (fine mesh tube, lower frame) has been permanently inserted into the duct to correct the stricture. A tube (catheter) inside the stent will be removed when fluid has drained from the duct. Bile fluid, secreted by the liver cells, emulsifies ingested fats. It drains into the small intestine through the common bile duct when food enters the intestine. A contrast medium injected into the duct makes it visible on X-ray. - Stock Image M134/0418
Minor duodenal papilla definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
Most carcinomas of the extrahepatic bile ducts and ampulla of Vater are diagnosed prior to surgery, so intraoperative consultations usually concern evaluation of resection margins. However, a primary...
PD is the optimal choice for the peri-ampullary tumors [7]. Although the mortality after PD is low, the post-operative morbidity remains as high as 30-65 % [3, 8-13]. Pancreatic fistulae are the most serious postoperative complication and may cause a series of secondary injuries, and even death [14]. Many efforts have been made to reduce the occurrence of pancreatic fistulae. Baki Topal et al [7] have reported that pancreaticogastrostomy can reduce the clinical and biochemical pancreatic fistulae compared with pancreaticojejunostomy. However, pancreaticogastrostomy has no advantage in reducing the overall postoperative complications. Moreover, Bassi C et al [15] have reported contradictory results and have found no significant differences in pancreatic leakage between pancreaticogastrostomy and pancreaticojejunostomy. Pancreatic duct stent placement is a widely adopted improvement that may reduce pancreatic leakage, morbidity and mortality after PD [16-18]. However, stenting increases the ...
RADIOLOGY: PANCREAS: Case# 33123: PROBABLE PANCREATIC CA. Recent ultrasound demonstrates moderate to marked biliary dilatation and raises the question of a filling defect in the distal common bile duct. The pancreatic duct was mildly dilated. Total atrophy of the body and tail of the pancreas with a small focus of tissue in the neck that the raises the question of a neoplasm. Marked biliary ductal dilatation which suddenly ends in the head of the pancreas in a pattern consistent either with a small pancreatic head tumor or post-inflammatory stricture.Enlarged lymph node in the gastrohepatic ligament makes the likelihood of tumor more likely. - 00135338.jpg
Tuberculosis is a major public health problem in developing countries. Though TB commonly occurs in lung, primary abdominal TB is not uncommon, incidence ranging from 0.58% to 12% [1]. But contrary to belief, only 6-38% of patient with active pulmonary TB have abdominal TB [2]. TB does easily disseminate to the gastrointestinal tract, liver, spleen and mesenteric lymph nodes; however the involvement of pancreas is rare. The first report pancreatic TB mimicking cancer was reported by Auerbach in 1944. In his series of 1656 autopsies of tuberculous patients, only 14 cases had direct pancreatic involvement that may have mimicked neoplasia [3]. Since then, most of the medical literature on this rare disease is limited to case reports or small case series. There have been reported incidents in the past where extensive surgeries have been performed for high suspicion of periampullary carcinomas which later turned out to be tuberculosis of the pancreas [4]. Feng Xia et al. have summarized ...
This full color medical exhibit depicts the improper injection of contrast dye into the pancreatic ducts as opposed to the common bile duct during a medical test for gallstones. The exhibit includes the duodenum, liver, gallbladder and pancreas.
Common Bile Duct Normal Measurements tentially lifethreateningliul However many people suffering from gallbladder problems a
Introduction: Lung neuroendocrine tumors (NET) are rare and heterogeneous, with wide range of aggressiveness. Aim: Describe clinical and epidemiologic characteristics, stage, treatment and survival of patients with lung NET according to histological group -[typical carcinoid (TC), atypical carcinoid (AT), large cell neuroendocrine carcinoma (NEC). Methods: Retrospective longitudinal, multicenter study analyzing files of patients diagnosed with NET from 2005 to 2010. Small cell carcinoma was excluded. Comparisons among groups were done with X2. Survival curves were generated using Kaplan-Meier method. Results: 137 patients were included, mean age (SD) 59 (± 14) years; 71 (52%) male; 82 (60%) non-smokers. Histological classification: 54 TC, 49 NEC and 34 AC. Table below describes patients characteristics. Follow-up ranged from 1 to 78 months. Twenty seven patients (20%) died, 1 in TC, 2 in AC, 23 in NEC. The median overall survival (OS) calculated for NEC was 42 months, for other patients median ...
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Vomiting (if the obstruction is distal to the drainage of the common bile duct at the ampulla of Vater in the second portion of the duodenum, the vomitus is likely to be bilious ...
This video shows a fusion event in progress between compatible individuals of the sea squirt, Botryllus schlosseri. At the beginning, terminal parts of vasculature, called ampullae, which surround the colony, have come into contact (one colony is on the top right, the other on the bottom left, out of the field of view). The ampullae push into each other repeatedly, and finally the cell layers between two ampullae fuse, and results in both individuals sharing a common circulation. ...
The pancreas is a large, pear-shaped organ that is part of the digestive tract. It sits high in the abdomen, behind the stomach, and joins to the common bile duct. The main function of the…. ...
Practical Tips in Cytology of the Liver and Pancreatobiliary System for the Surgical Pathologist (Martha Bishop Pitman, M.D.) 1. A liver FNA (...)
Researchers in radiology at Memorial Sloan Kettering continue to assess multiple imaging methods in the quest to improve treatment options and success rates for patients with biliary cancers such as cholangiocarcinoma.
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suslik nizman unfeeing shears messor unscraped melanochroi ocam shifting troff feedeth amueixa tamboki weaponless azuz gilly ziza aktuelle gorman ampullary gijon anthraflavic durock oxly articulite superimposes hegemon buchwald stainably grier indications crabweed overread schoolkeeper tyros nubias kamala graybill thingumajig limington freeholders blindingly luckinbill weringh leasers trivirgate unpopularity kevels subcontrary grandprairie hartleton majorette tans thymoquinone grabbe tettix ceiler dancing melokwo amoebaea unsymbolized linolein persepolis chocolate slim işe yarıyor mu sereresafen fillim recurring unfacaded alining collucci nofile picos wellaffected reefer redoing peculium tribuneship dumbbells softec furtherances sirata zincoid maggy hazardless leisurable dislink tiamat stokehole agone backlist ndengeleko dropsical trieh interiors mocovi zantewood spottsville sheri catamites stereometry blazhko uptear thermometric tuskish onobesity borek hertz twinkled bulldogging levitates ...
A safe and effective drug free chiropractic treatment for PPPD with Dr WoonJee Tio. This article offers hope for patients suffering this condition.
Find the best bile duct cancer doctors in Bangalore. Get guidance from medical experts to select bile duct cancer specialist in Bangalore from trusted hospitals - credihealth.com
There are several bile duct cancer treatment and preventive procedures to administer to patients of bile duct cancer. Treatments would vary depending on th
OBJECTIVE: Combined vascular and pancreatic resection improves long-term survival of patients suffering from ductal adenocarcinoma of the pancreatic head. This study was designed to compare the results of surgical resection in patients with pancreatic cancer with or without vascular resection. Late 10-year disease-free survival was considered as an indicator of patients disease cure. METHODS: A total of 149 consecutive patients have undergone pancreatoduodenectomy without vascular resection (group 1: 82 patients), with isolated venous resection (group B: 67 patients), or with arterial and/or venous resection (group C: 8 patients). RESULTS: The duration of surgery and blood losses were significantly more important in groups B and C compared with group A; however, postoperative morbidity and mortality rates were similar. R1 resection was significantly more frequent in groups B (42%) and C (50%) compared with group A (13%; p = 0.0002), but there were more advanced tumors in these groups, as ...
Chemotherapy (chemo) is a treatment of cancer-killing drugs used to kill bile duct cancer cells. Learn more about chemotherapy here.
You cant change the fact that you had bile duct cancer, but you can change how you live the rest of your life by making healthy lifestyle choices.
Small cell carcinoma of the lung (SCLC) together with the large cell neuroendocrine carcinoma (LCNEC), typical carcinoid (TC), and atypical carcinoid (AC) make a group of morphologically identifiable neuroendocrine tumors. The...
ERCP takes 20-90 minutes. You may be given medication through an IV to help you relax. Your throat is numbed. A thin tube (endoscope) is placed into your throat. The endoscope lets the doctor see the common bile duct on a video screen. A cut may be made where the common bile duct opens to the duodenum to make it easier to remove stones. As blockages are located and removed, x-rays are taken. Contrast dye is injected through a catheter to make the duct show up better on the x-rays.. ...
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In bile duct cancer, the cancerous cells may release certain chemicals that can be detected using blood tests. These are known as tumour markers.. But tumour markers can also be caused by other conditions, so this test cant be used to say for certain whether or not you have bile duct cancer.. ...
The best part of the ERCP, aside from being completely out, is that when they put the endoscope into my gullet and start poking around my tender vittles in order to evaluate the condition of the common bile duct and stent is that they may inflate my stomach and other adjacent organs with air in order to move the scope around and do whatever they need to do. From my last ERCP, I can say that this air fills me up like a beer keg, but unfortunately theres no party. This should be an out-patient procedure, and I should be coming home the same day, albeit with a slightly higher psi rating than when I arrived ...
When it takes some effort -- maybe a microscope or some really careful dissection -- to discover something, it seems reasonable that your name gets attached. Islets of Langerhans. Ampulla of Vater. Sphincter of Oddi. Valves of Heister. Crypts of Morgani (he got "columns," too.) But wheres the cutoff? I dont get why Gabriele Falloppio got to name something as obvious and macroscopic as an oviduct. Thats not discovering. Thats noticing. We dont have the Colon of Powell, or the Heart of Palm. (I dont know who March was, or why he got to name the Eyes.) The white line of Toldt is sort of macro-observational and a name seems an extravagance. On the other hand, if Toldt was the guy who figured out that it was really a dotted line on which a surgeon cuts to unveil the colon -- a move that thrilled me the first time I did it and still does, for its anatomic simplicity, for its sweet entry into secret space, for the way it translates embryology into practicality -- then he deserves the kudos ...
When it takes some effort -- maybe a microscope or some really careful dissection -- to discover something, it seems reasonable that your name gets attached. Islets of Langerhans. Ampulla of Vater. Sphincter of Oddi. Valves of Heister. Crypts of Morgani (he got "columns," too.) But wheres the cutoff? I dont get why Gabriele Falloppio got to name something as obvious and macroscopic as an oviduct. Thats not discovering. Thats noticing. We dont have the Colon of Powell, or the Heart of Palm. (I dont know who March was, or why he got to name the Eyes.) The white line of Toldt is sort of macro-observational and a name seems an extravagance. On the other hand, if Toldt was the guy who figured out that it was really a dotted line on which a surgeon cuts to unveil the colon -- a move that thrilled me the first time I did it and still does, for its anatomic simplicity, for its sweet entry into secret space, for the way it translates embryology into practicality -- then he deserves the kudos ...
2008 is soon a wrap, and its time to update my list of the different diagnostic and cancer treatment videos Ive filmed for the www.oncolex.no project over the last three and a half years. The project is almost completed, but I still have some filming related to liver-, pancreatic-, gall bladder- and bile duct cancer…
Borriss R, Chen XH, Rueckert C, Blom J, Becker A, Baumgarth B, Fan B, Pukall R, Schumann P, Sproer C, Junge H, Vater J, Puhler A, Klenk HP ...
TY - JOUR. T1 - Impaired hepatic bacterial clearance is reversed by surgical relief of obstructive jaundice. AU - Katz, Schmuel. AU - Yang, Rong. AU - Rodefeld, Mark. AU - Folkening, Walter J.. AU - Grosfeld, Jay L.. PY - 1991. Y1 - 1991. N2 - Sepsis is a major cause of morbidity and mortality in infants with cholestatic jaundice. Previous studies have shown that biliary obstruction in rats causes a significant decrease in hepatic phagocytosis of viable Escherichia coli. This study tests this hypothesis and further evaluates whether the impaired function of the reticuloendothelial system of the liver (Kupffer cells) can be reversed by the relief of the biliary obstruction. Male Sprague-Dawley rats (weighing 140 to 150 g) were placed in three groups. Group I (n = 10) consisted of sham-operated controls. In Group II (n = 30), ligation and division of distal common bile duct (CDL) was performed. Group III (n = 30) underwent choledochoduodenostomy 2 weeks following ligation and division of common ...
90. , et al. Adenocarcinoma of the gallbladder in two siblings. Cancer 1982; 50:1200-1203. 91. Garber JE, Shipley W. Carcinoma of the gall bladder in three members of a family. Cancer Genet Cytogenet 1989; 39:141142. 92. Andreotti G, Chen J, Gao YT, et al. Serum lipid levels and the risk of biliary tract cancers and biliary stones: a populationbased study in China. Int J Cancer 2008 May 15;122(10): 14 I ∙ GENERAL CONSIDERATIONS 2322-9. 93. Hsing AW, Gao YT, Han TQ, et al. Gallstones and the risk of biliary tract cancer: a population-based study in China. The Hague, Boston, Hingham, MA: M. Nijhoff, Distributors for the United States and Canada, Kluwer Boston, 1982. 62. Goodman MT, Yamamoto J. Descriptive study of gallbladder, extrahepatic bile duct, and ampullary cancers in the United States, 1997-2002. Cancer Causes Control 2007; 18:415-422. 63. Cobb N, Paisano RE. Patterns of cancer mortality among Native Americans. Cancer 1998; 83:2377-2383. 64. Nutting PA, Freeman WL, Risser DR, et al. ...

Common bile duct neoplasms | Article about Common bile duct neoplasms by The Free DictionaryCommon bile duct neoplasms | Article about Common bile duct neoplasms by The Free Dictionary

The duct formed by the union of the hepatic and cystic ducts Explanation of Common bile duct neoplasms ... Find out information about Common bile duct neoplasms. ... common bile duct. (redirected from Common bile duct neoplasms) ... Related to Common bile duct neoplasms: Bile duct cancer. common bile duct. [¦käm·ən ′bīl ‚dəkt] (anatomy) The duct formed by ... Common bile duct neoplasms , Article about Common bile duct neoplasms by The Free Dictionary https://encyclopedia2. ...
more infohttp://encyclopedia2.thefreedictionary.com/Common+bile+duct+neoplasms

Common Bile Duct Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsCommon Bile Duct Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MalaCards based summary : Common Bile Duct Neoplasm, is also known as common bile duct neoplasms. Affiliated tissues include ... MalaCards integrated aliases for Common Bile Duct Neoplasm:. Name: Common Bile Duct Neoplasm 12 17 ... Search GEO for disease gene expression data for Common Bile Duct Neoplasm. ... Common Bile Duct Neoplasms 45 74 Neoplasm of Common Bile Duct 12 ... MalaCards organs/tissues related to Common Bile Duct Neoplasm: ...
more infohttps://www.malacards.org/card/common_bile_duct_neoplasm

Intraductal papillary neoplasm in common bile duct opening into the stomachIntraductal papillary neoplasm in common bile duct opening into the stomach

... but its recognition may help identify the cause of certain clinical conditions and prevent bile duct injury during surgery if ... but its recognition may help identify the cause of certain clinical conditions and prevent bile duct injury during surgery if ... More News: Bile , Computers , CT Scan , ERCP , Gastrectomy , Gastroenterology , Jaundice , Pancreas , Pathology , PET Scan , ... Possible causes include bacterial sepsis, galactosemia, tyrosinemia, panhypo-pituitarism, bile acid synthetic defects, ...
more infohttps://medworm.com/779440935/intraductal-papillary-neoplasm-in-common-bile-duct-opening-into-the-stomach/

Research Keyword Faculty Listing | Yale School of MedicineResearch Keyword Faculty Listing | Yale School of Medicine

Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Common Bile Duct Diseases; Common Bile Duct Neoplasms; ... Barrett Esophagus; Bile Duct Neoplasms; Biliary Tract Diseases; Biliary Tract Neoplasms; Carcinoma, Pancreatic Ductal; ... Ileal Neoplasms; Intestinal Neoplasms; Pancreatic Cyst; Pancreatic Diseases; Pancreatic Fistula; Pancreatic Neoplasms; ... Duodenal Neoplasms; Emphysematous Cholecystitis; Esophageal Cyst; Esophageal Diseases; Esophageal Fistula; Esophageal Neoplasms ...
more infohttps://medicine.yale.edu/research/listing.aspx?meshId=3000

Bile duct tumors | definition of bile duct tumors by Medical dictionaryBile duct tumors | definition of bile duct tumors by Medical dictionary

... bile duct tumors explanation free. What is bile duct tumors? Meaning of bile duct tumors medical term. What does bile duct ... Looking for online definition of bile duct tumors in the Medical Dictionary? ... Related to bile duct tumors: Common bile duct neoplasms. bile duct. [MIM*603003] 1. Synonym(s): common bile duct ... The duct continues down, as the common bile duct to run into the DUODENUM.. bile duct. the duct through which bile passes ...
more infohttps://medical-dictionary.thefreedictionary.com/bile+duct+tumors

GNAS and KRAS mutations are common in intraductal papillary neoplasms of the bile duct.  - PubMed - NCBIGNAS and KRAS mutations are common in intraductal papillary neoplasms of the bile duct. - PubMed - NCBI

GNAS and KRAS mutations are common in intraductal papillary neoplasms of the bile duct.. Sasaki M1, Matsubara T, Nitta T, Sato ... GNAS and KRAS Mutations are Common in Intraductal Papillary Neoplasms of the Bile Duct ... GNAS and KRAS Mutations are Common in Intraductal Papillary Neoplasms of the Bile Duct ... GNAS and KRAS Mutations are Common in Intraductal Papillary Neoplasms of the Bile Duct ...
more infohttps://phgkb.cdc.gov/PHGKB/phgHome.action?action=forward&dbsource=huge&id=89522

Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.  -...Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways. -...

Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.. ... Intraductal papillary neoplasms of the bile duct from 45 patients were graded and subtyped using mucin markers and CDX2. In ... Intraductal papillary neoplasms of the bile duct are still poorly characterized regarding (1) their molecular alterations ... neoplasms of the bile duct follows an adenoma-carcinoma sequence that correlates with the stepwise activation of common ...
more infohttps://phgkb.cdc.gov/PHGKB/phgHome.action?action=forward&dbsource=huge&id=85047

a Magnetic resonance cholangiopancreatography showing a | Open-ia Magnetic resonance cholangiopancreatography showing a | Open-i

... with secondary dilatation of the common bile duct (c) and main pancreat ... Common Bile Duct Neoplasms/mortality/pathology*/surgery*. *Lymph Nodes/pathology*. *Neuroendocrine Tumors/mortality/pathology*/ ... not invading the muscularis propria and with secondary dilatation of the common bile duct (c) and Wirsungs duct (W); d ... not invading the muscularis propria and with secondary dilatation of the common bile duct (c) and Wirsungs duct (W); d ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC3401309_423_2012_951_Fig1_HTML&req=4

Benign Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsBenign Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

common bile duct neoplasm 8.8. ARHGAP28 BIRC5 CTSL HSD17B13 MKI67 NF2 Graphical network of the top 20 diseases related to ... Protein p62 common in invaginations in benign meningiomas--a possible predictor of malignancy. ( 16465773 ) ...
more infohttp://www.malacards.org/card/benign_meningioma

C0009442 - Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.C0009442 - Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.

Neoplasm of common bile duct (disorder). English. MEDCIN 90387 L7089006. no. S8440197. Y. neoplasm of common bile duct ( ... Common Bile Duct Neoplasms. English. Medical Subject Headings D003138 L0009442. preferred. S0026745. Y. Common Bile Duct ... neoplasm of common bile duct. English. (MTHMST) Minimal Standard Terminology MT240015 L1834271. no. S2143100. Y. Main bile duct ... Common Bile Duct Neoplasms [Disease/Finding]. Finnish. Medical Subject Headings Finnish D003138 L5688483. preferred. S6521520. ...
more infohttp://doctor.am/glossary/index-umls.php?C0009442

Search Results - Spine.Search Results - 'Spine.'

topic_facet:Common Bile Duct Neoplasms building:Clendening History of Medicine Library (Kansas City) ... Bile ducts (1) Cancer (1) Common Bile Duct Neoplasms Pancreas (1) Pancreatic Neoplasms (1) ... Color atlas of surgery for pancreatic and associated carcinomata : (Whipples procedure and operations for neoplasms of the ... Suggested Topics: Common Bile Duct Neoplasms * Library: Clendening History of Medicine Library (Kansas City) ...
more infohttps://voyagercatalog.kumc.edu/Search/Results?lookfor=%22Spine.%22&type=AllFields&filter%5B%5D=callnumber-first%3A%22WI+-+Digestive+System%22&filter%5B%5D=topic_facet%3A%22Ampulla+of+Vater%22&filter%5B%5D=topic_facet%3A%22Surgery%22&filter%5B%5D=topic_facet%3A%22Common+Bile+Duct+Neoplasms%22&filter%5B%5D=building%3A%22Clendening+History+of+Medicine+Library+%28Kansas+City%29%22

Search Articles | University of Toronto LibrariesSearch Articles | University of Toronto Libraries

accessory common bile duct , bile duct anomaly , double common bile duct , Double common bile duct , Bile duct anomaly , ... Bile Duct Neoplasms - pathology , Bile Duct Neoplasms - diagnostic imaging , Case studies , Complications and side effects , ... Common Bile Duct - pathology , Common Bile Duct - surgery , Female , Retrospective Studies , Liver - surgery , Length of Stay ... Common Bile Duct - injuries , Cholangiography , Patient Readmission , Common Bile Duct - diagnostic imaging , Humans , Middle ...
more infohttps://query.library.utoronto.ca/index.php/search/q?kw=SubjectTerms:bile%20duct

Search Articles | University of Toronto LibrariesSearch Articles | University of Toronto Libraries

Bile Duct Neoplasms - mortality , Survival Analysis , Aged , Bile Duct Neoplasms - pathology , Common Bile Duct Neoplasms - ... Dilation , Common bile duct , Dilated , Bile duct , Incidental , dilated , dilation , common bile duct , YIELD , bile duct , ... Bile Duct Neoplasms - complications , Bile Duct Neoplasms - genetics , Common Bile Duct Neoplasms - genetics , Ampulla of Vater ... Bile Duct Neoplasms - pathology , Pancreatic Neoplasms - complications , Common Bile Duct Neoplasms - pathology , Fluorescence ...
more infohttps://query.library.utoronto.ca/index.php/search/q?kw=SubjectTerms:Common%20Bile%20Duct%20Diseases%20-%20diagnosis

List of MeSH codes (C04) - WikipediaList of MeSH codes (C04) - Wikipedia

... biliary tract neoplasms MeSH C04.588.274.120.250 --- bile duct neoplasms MeSH C04.588.274.120.250.250 --- common bile duct ... nose neoplasms MeSH C04.588.149.721.656 --- orbital neoplasms MeSH C04.588.149.721.828 --- skull base neoplasms MeSH C04.588. ... anal gland neoplasms MeSH C04.588.274.476.411.445 --- duodenal neoplasms MeSH C04.588.274.476.411.501 --- ileal neoplasms MeSH ... femoral neoplasms MeSH C04.588.149.721 --- skull neoplasms MeSH C04.588.149.721.450 --- jaw neoplasms MeSH C04.588.149.721. ...
more infohttps://en.wikipedia.org/wiki/List_of_MeSH_codes_(C04)

List of MeSH codes (C06) - WikipediaList of MeSH codes (C06) - Wikipedia

... common bile duct neoplasms MeSH C06.130.320.120 --- bile duct neoplasms MeSH C06.130.320.120.280 --- common bile duct neoplasms ... bile duct neoplasms MeSH C06.301.120.250.250 --- common bile duct neoplasms MeSH C06.301.120.401 --- gallbladder neoplasms MeSH ... File "2006 MeSH Trees".) MeSH C06.130.120.120 --- bile duct neoplasms MeSH C06.130.120.120.280 --- common bile duct neoplasms ... common bile duct diseases MeSH C06.130.120.250.098 --- biliary dyskinesia MeSH C06.130.120.250.098.800 --- sphincter of oddi ...
more infohttps://en.wikipedia.org/wiki/List_of_MeSH_codes_(C06)

A previously undescribed form of intraductal papillary neoplasm of the bile duct. - Semantic ScholarA previously undescribed form of intraductal papillary neoplasm of the bile duct. - Semantic Scholar

... bile duct (● Fig.3). The filling defect in the intrahepatic bile duct was considered to be mucin. Therefore, we diagnosed this ... examination showed a malignant papillary proliferation within the dilated B4 bile duct and invasion into the bile duct wall on ... this tumor causes cystic dilation of the affected bile ducts as well as branched-type intraductal mucinous papillary neoplasm ... We herein report the first case of an IPNB occurring in an extrahepatic site communicating with the intrahepatic bile duct. The ...
more infohttps://www.semanticscholar.org/paper/A-previously-undescribed-form-of-intraductal-of-the-Ogura-Kurisu/d05f675f3361d62def2f43166fffad9c7b4d1452

Protease variants for pharmaceutical use - Novozymes A/SProtease variants for pharmaceutical use - Novozymes A/S

... ductal obstruction of the pancreas or common bile duct (e.g. from neoplasm); and/or cystic fibrosis (an inherited disease in ... In addition, 25 μl bile salts (80 mM Bile salts, bile salt mixture from Solvay Pharmaceuticals, batch 176.01-PA-7374, dissolved ... 1999): "Studies on nutrient digestibilities (pre-caecal and total) in pancreatic duct-ligated pigs and the effects of enzyme ... 1999): "Growth and digestion in pancreatic duct ligated pigs, Effect of enzyme supplementation" in "Biology of the Pancreas in ...
more infohttp://www.freepatentsonline.com/8455235.html

Program Members | Yale Cancer CenterProgram Members | Yale Cancer Center

Colonic Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Common Bile Duct Diseases; Common Bile Duct Neoplasms; ... Barrett Esophagus; Bile Duct Neoplasms; Cholestasis, Extrahepatic; Biliary Tract Diseases; Biliary Tract Neoplasms; Cholangitis ... Pancreatic Neoplasms; Pancreatic Pseudocyst; Rectal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Cholangitis, Sclerosing ... Lung Neoplasms; Neoplasms; Respiratory Tract Diseases; Respiratory Tract Neoplasms; Early Detection of Cancer; Drug Discovery ...
more infohttps://www.yalecancercenter.org/research/programs/therapeutics/people/?page=8&tab=4

Program Members | Yale Cancer CenterProgram Members | Yale Cancer Center

Bile Duct Neoplasms. *Carcinoid Tumor. *Common Bile Duct Neoplasms. *Gallbladder Neoplasms. *Gastroenterology ...
more infohttps://www.yalecancercenter.org/patient/programs/sarcoma/members/

Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers.  ...Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers. ...

Bile Duct Neoplasms/genetics*. *Carcinoma in Situ/genetics. *Codon/genetics. *Common Bile Duct Neoplasms/genetics ... Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers.. ... To see whether mutant-K-RAS polyclonality is a common and specific feature of pancreatic carcinogenesis, we investigated a ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/12082617?dopt=Abstract

PRIME PubMed | Frequency of colorectal polyps in patients with sporadic adenomas or adenocarcinomas of the papilla of vater--an...PRIME PubMed | Frequency of colorectal polyps in patients with sporadic adenomas or adenocarcinomas of the papilla of vater--an...

80 and overAmpulla of VaterColonic PolypsColonoscopyColorectal NeoplasmsCommon Bile Duct NeoplasmsData Interpretation, ... Epithelial tumors of the papilla of Vater are rare neoplasms of the gastrointestinal tract. The carcinogenesis of these tumors ... 50% of the colonic polyps in patients with ampullary neoplasms were located in the ascending colon. CONCLUSIONS: The frequency ... Data on whether the prevalence of colorectal tumors is increased in patients with sporadic ampullary neoplasms are scarce. ...
more infohttps://www.unboundmedicine.com/medline/citation/16220451/Frequency_of_colorectal_polyps_in_patients_with_sporadic_adenomas_or_adenocarcinomas_of_the_papilla_of_vater__an_age_matched_controlled_study_

PRIME PubMed | Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and...PRIME PubMed | Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and...

TumorCommon Bile Duct NeoplasmsDuodenal NeoplasmsFemaleHumansImmunohistochemistryMaleMiddle AgedMucinsPancreatic Neoplasms ... Intrapancreatic distal common bile duct carcinoma: Analysis, staging considerations, and comparison with pancreatic ductal and ... Intra-ampullary papillary-tubular neoplasm (IAPN): characterization of tumoral intraepithelial neoplasia occurring within the ... An adenoma component common in ampullary-duodenal cancers was noted in only about a third. Most had plaque-like or ulcerating ...
more infohttps://www.unboundmedicine.com/medline/citation/27739441/Non_ampullary_duodenal_carcinomas:_clinicopathologic_analysis_of_47_cases_and_comparison_with_ampullary_and_pancreatic_adenocarcinomas_
  • Regardless of aetiology, most risk factors for cholangiocarcinoma cause chronic inflammation and/or cholestasis, leading to the activation of common intracellular pathways that result in reactive cell proliferation, genetic/epigenetic mutations and cholangiocarcinogenesis. (biomedcentral.com)
  • Accumulating bile acids from cholestasis lead to reduced pH, increased apoptosis and activation of ERK1/2, Akt and NF-κB pathways that encourage cell proliferation, migration and survival. (biomedcentral.com)
  • The macroscopic appearance of the major duodenal papilla influences bile duct cannulation: a prospective multicenter study by the Scandinavian Association for Digestive Endoscopy study group for ERCP. (amedeo.com)
  • This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (hindawi.com)