Common Bile Duct Diseases
Bile Duct Diseases
Common Bile Duct
Bile Ducts
Gallstones
Common Bile Duct Neoplasms
Cholangiopancreatography, Endoscopic Retrograde
Cholangiography
Bile
Bile Ducts, Extrahepatic
Cholestasis
Cholestasis, Extrahepatic
Cholecystectomy, Laparoscopic
Sphincterotomy, Endoscopic
Bile Acids and Salts
Bile Ducts, Intrahepatic
Jaundice, Obstructive
Cholangiopancreatography, Magnetic Resonance
Sphincter of Oddi
Cholangitis
Cystic Duct
Cholelithiasis
Ampulla of Vater
Biliary Tract Diseases
Pancreatic Ducts
Hepatic Duct, Common
Gallbladder
Pancreatitis
Sphincterotomy, Transhepatic
Choledochal Cyst
Biliary Fistula
Choledochostomy
Endoscopes
Cholecystitis
Imino Acids
Gallbladder Diseases
Jaundice
Lithotripsy
Adenomyoma
Technetium Tc 99m Disofenin
Dilatation, Pathologic
Endoscopy
Cholestasis, Intrahepatic
Cholecystitis, Acute
Pancreaticoduodenectomy
Sphincter of Oddi Dysfunction
Jejunostomy
Duodenum
Liver
Postoperative Complications
Cholecystostomy
Bile Reflux
Endosonography
Liver Cirrhosis, Experimental
Constriction, Pathologic
Intraoperative Care
Catheterization
Liver Function Tests
Duodenal Diseases
Thoracic Duct
Calculi
Liver Cirrhosis, Biliary
Ascaridida
Surgical Instruments
Treatment Outcome
Lithiasis
Hepatopulmonary Syndrome
Colic
Intraoperative Complications
Pancreas
Retrospective Studies
Laparoscopy
Ursodeoxycholic Acid
Tomography, X-Ray Computed
Pancreatitis, Chronic
Anastomosis, Roux-en-Y
Diverticulum
Adenoma, Villous
Bile Canaliculi
Anastomosis, Surgical
Cholagogues and Choleretics
Postcholecystectomy Syndrome
Adenocarcinoma, Papillary
Fascioliasis
Preoperative Care
Obstructive jaundice and acute cholangitis due to papillary stenosis. (1/141)
Papillary stenosis is characterized by fixed fibrosis leading to structural outflow obstruction and it is usually secondary to inflammation and fibrosis from the chronic passage of gallstones, episodes of acute pancreatitis, chronic pancreatitis, sclerosing cholangitis, peptic ulcer disease, and cholesterolosis. However, obstructive jaundice with or without acute cholangitis which leads the physician to suspect the presence of malignancy as a cause is a rare manifestation of papillary stenosis. We report here a case of papillary stenosis presenting with obstructive jaundice and acute cholangitis. The lesion was so difficult to exclude the presence of malignancy preoperatively and intraoperatively that a pylorus-preserving pancreaticoduodenectomy was performed. Histologic examination of the resected specimen revealed fibrosis, adenomatoid ductal hyperplasia, and mild chronic inflammation of the papilla of Vater and distal common bile duct. (+info)Endoscopic retrograde cholangiopancreatography in elderly patients. (2/141)
BACKGROUND: the presentation of common bile duct disease, value of investigations and treatment outcome in elderly patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) were assessed. METHODOLOGY: the clinical presentation, liver function tests, full blood counts, abdominal ultrasound and ERCP results were assessed retrospectively in 101 patients (59 women, 42 men; mean age 83 years, range 75-100) sequentially investigated for possible common bile duct disease. RESULTS: 59 patients had common bile duct gallstones, 35 had malignant biliary obstruction (13 with co-existing common bile duct stones) and seven had other outcomes. In the malignant-alone group 68% of those who had jaundice presented painlessly compared with 24% in the gallstones-alone group; 49% of the gallstones-alone group had pain compared with 28% of the malignant group. In the gallstones-alone group 43% had atypical presentations (non-specific symptoms or painless jaundice). Non-specific symptoms were found in 19% of the gallstones-alone group but in only 5% of the malignant group. Of the patients who had common bile duct stones, 18% had pancreatic or biliary malignancy. The co-existence of gallstones and malignancy was emphasized by eight patients in whom the clinical and ultrasound diagnosis was of common bile duct stones but malignancy was detected by ERCP. The sensitivity of ultrasound was 86% for detecting dilated common bile ducts was 86%, but only 69% for diagnosing gallstones within the common bile duct and 67% for diagnosing pancreatic masses. Ultrasound and ERCP were in agreement in 60 patients (60%). Endoscopic clearance of common bile duct gallstones was successful in 53 of 54 attempts (98%). Palliative ERCP treatment was performed in 30 patients who had malignant biliary obstruction and was successful in 22 (73%); in a further four patients (13%) an endoprothesis was successfully inserted percutaneously. The commonest complication of ERCP was cholangitis (four patients); pancreatitis and biliary perforation occurred in one patient each. Twenty-two patients (63%) who had malignancy died during follow-up, the mean survival being 11.3 weeks (range 3 days-2 years). Carcinoma of the ampulla was associated with a relatively good prognosis (three patients survived 18 months or more). CONCLUSION: in elderly patients, common bile duct stones often present atypically and co-existence with malignancy is not unusual; ampullary carcinoma has a relatively good prognosis and ERCP is a safe and effective procedure in the management of biliary obstruction. (+info)Functional disorders of the biliary tract and pancreas. (3/141)
The term "dysfunction" defines the motor disorders of the gall bladder and the sphincter of Oddi (SO) without note of the potential etiologic factors for the difficulty to differentiate purely functional alterations from subtle structural changes. Dysfunction of the gall bladder and/or SO produces similar patterns of biliopancreatic pain and SO dysfunction may occur in the presence of the gall bladder. The symptom-based diagnostic criteria of gall bladder and SO dysfunction are episodes of severe steady pain located in the epigastrium and right upper abdominal quadrant which last at least 30 minutes. Gall bladder and SO dysfunctions can cause significant clinical symptoms but do not explain many instances of biliopancreatic type of pain. The syndrome of functional abdominal pain should be differentiated from gall bladder and SO dysfunction. In the diagnostic workup, invasive investigations should be performed only in the presence of compelling clinical evidence and after non-invasive testing has yielded negative findings. Gall bladder dysfunction is suspected when laboratory, ultrasonographic, and microscopic bile examination have excluded the presence of gallstones and other structural abnormalities. The finding of decreased gall bladder emptying at cholecystokinin-cholescintigraphy is the only objective characteristic of gall bladder dysfunction. Symptomatic manifestation of SO dysfunction may be accompanied by features of biliary obstruction (biliary-type SO dysfunction) or significant elevation of pancreatic enzymes and pancreatitis (pancreatic-type SO dysfunction). Biliary-type SO dysfunction occurs more frequently in postcholecystectomy patients who are categorized into three types. Types I and II, but not type III, have biochemical and cholangiographic features of biliary obstruction. Pancreatic-type SO dysfunction is less well classified into types. When non-invasive investigations and endoscopic retrograde cholangiopanreatography show no structural abnormality, manometry of both biliary and pancreatic sphincter may be considered. (+info)Manometry based randomised trial of endoscopic sphincterotomy for sphincter of Oddi dysfunction. (4/141)
BACKGROUND: Endoscopic sphincterotomy for biliary-type pain after cholecystectomy remains controversial despite evidence of efficacy in some patients with a high sphincter of Oddi (SO) basal pressure (SO stenosis). AIM: To evaluate the effects of sphincterotomy in patients randomised on the basis of results from endoscopic biliary manometry. METHODS: Endoscopic biliary manometry was performed in 81 patients with biliary-type pain after cholecystectomy who had a dilated bile duct on retrograde cholangiography, transient increases in liver enzymes after episodes of pain, or positive responses to challenge with morphine/neostigmine. The manometric record was categorised as SO stenosis, SO dyskinesia, or normal, after which the patient was randomised in each category to sphincterotomy or to a sham procedure in a prospective double blind study. Symptoms were assessed at intervals of three months for 24 months by an independent observer, and the effects of sphincterotomy on sphincter function were monitored by repeat manometry after three and 24 months. RESULTS: In the SO stenosis group, symptoms improved in 11 of 13 patients treated by sphincterotomy and in five of 13 subjected to a sham procedure (p = 0.041). When manometric records were categorised as dyskinesia or normal, results from sphincterotomy and sham procedures did not differ. Complications were rare, but included mild pancreatitis in seven patients (14 episodes) and a collection in the right upper quadrant, presumably related to a minor perforation. At three months, the endoscopic incision was extended in 19 patients because of manometric evidence of incomplete division of the sphincter. CONCLUSION: In patients with presumed SO dysfunction, endoscopic sphincterotomy is helpful in those with manometric features of SO stenosis. (+info)Use of (99m)Tc-DISIDA biliary scanning with morphine provocation for the detection of elevated sphincter of Oddi basal pressure. (5/141)
BACKGROUND: Endoscopic biliary manometry is useful in the assessment of patients with types II and III sphincter of Oddi dysfunction, but it is time consuming and invasive. AIM: To investigate the role of (99m)Tc-DISIDA scanning, with and without morphine provocation, as a non-invasive investigation in these patients compared with endoscopic biliary manometry. SUBJECTS AND METHODS: A total of 34 patients with a clinical diagnosis of type II (n = 21) or III (n = 13) sphincter of Oddi dysfunction were studied. Biliary scintigraphy with 100 MBq of (99m)Tc-DISIDA was carried out with and without morphine provocation (0.04 mg/kg intravenously) and time/activity curves were compared with the results of subsequent endoscopic biliary manometry. RESULTS: Eighteen (nine type II, nine type III) of the 34 (53%) patients had sphincter of Oddi basal pressures above the upper limit of normal (40 mm Hg). In the standard DISIDA scan without morphine, no significant differences were observed in time to maximal activity (Tmax) or percentage excretion at 45 or 60 minutes between those with normal and those with abnormal biliary manometry. However, following morphine provocation, median percentage excretion at 60 minutes was 4.9% in those with abnormal manometry and 28.2% in the normal manometry group (p = 0.002). Using a cut off value of 15% excretion at 60 minutes, the sensitivity for detecting elevated sphincter of Oddi basal pressure by the morphine augmented DISIDA scan was 83% and specificity was 81%. Also, 14 of the 18 patients with abnormal manometry complained of biliary-type pain after morphine infusion compared with only two of 16 patients in the normal manometry group (p = 0.001). CONCLUSIONS: (99m)Tc-DISIDA with morphine provocation is a useful non-invasive investigation for types II and III sphincter of Oddi dysfunction to detect those with elevated sphincter basal pressures who may respond to endoscopic sphincterotomy. (+info)Biliary stenting versus bypass surgery for the palliation of malignant distal bile duct obstruction: a meta-analysis. (6/141)
The objective of this analysis is to compare endoscopic stenting with surgical bypass in patients with unresectable, malignant, distal common bile duct obstruction using the technique of meta-analysis. The inclusion criteria for the studies were randomized patient assignment, publication in the English language, 20 or more patients per group, all patients followed up until death, and follow-up and complications reported in an equivalent way for both treatment arms. Data extraction was performed independently by 2 of the authors. The number of treatment failures, serious complications, requirement for additional treatment sessions, and 30-day mortality were extracted. Three existing trials met the inclusion criteria, all of which compared surgery with the use of plastic stents. There were no studies identified that used metallic expandable stents. For the rate of treatment failure and serious complications, the odds ratios (ORs) of the 3 trials were heterogeneous, and no summary ORs were calculated. More treatment sessions were required after stent placement than after surgery, and a common OR was estimated to be 7.23 (95% confidence interval [CI], 3.73 to 13.98). Thirty-day mortality was not significantly different (OR = 0.522; 95% CI, 0.263 to 1.036). Although surgical bypass required fewer additional treatment sessions, existing data do not allow a definitive conclusion on which treatment is preferable. A larger randomized controlled trial using newer metallic stents and proper quality-of-life instruments is required. (+info)Repair of common bile duct injury with the round and falciform ligament after clip necrosis: case report. (7/141)
Occasionally, as abdominal surgeons, we are confronted with common bile duct injury noted during video laparoscopic or open cholecystectomy. Usually this is solved by endoscopic retrograde cholangiopancreatography (ERCP) sphincterotomy and stent, or enteric bypass, suture repair and tube drainage. However, after such procedures, there is a significant number of patients with postoperative stenosis. Another alternative to repair common bile duct injury and correct postoperative stenosis is using the round and falciform ligament as circumferencial patch. Due to their closeness to the common bile duct and their adequate blood supply, they make a perfect autologous biological graft. (+info)Vanishing bile duct syndrome in Hodgkin's disease: case report. (8/141)
CONTEXT: Liver damage is relatively common in patients affected by Hodgkin's disease. A smaller proportion of cases develops jaundice. Recently, the vanishing bile duct syndrome was described in Hodgkin's disease. The mechanisms of this severe complication have been poorly understood until now. OBJECTIVE: To describe a rare case of intra-hepatic cholestasis due to vanishing bile duct syndrome. DESIGN: Case report. CASE REPORT: A 38-year-old male patient affected by Hodgkin's disease. Liver biopsy showed no detectable Hodgkin's disease. Intra-hepatic cholestasis was found and none of the six portal tracts analyzed contained normal bile ducts. The treatment was based on conventional and high-dose escalation chemotherapy. The patient died from an irreversible liver failure while in complete remission from Hodgkin's disease. (+info)Common bile duct diseases refer to a group of medical conditions that affect the common bile duct, which is a tube that carries bile from the liver to the small intestine. The common bile duct is responsible for transporting bile produced by the liver to help with digestion and absorption of fats. Some common bile duct diseases include: 1. Cholangitis: Inflammation of the bile ducts, which can be caused by a blockage or infection. 2. Cholecystitis: Inflammation of the gallbladder, which can cause blockage of the common bile duct. 3. Choledocholithiasis: Formation of stones in the common bile duct, which can cause blockage and lead to inflammation. 4. Pancreatitis: Inflammation of the pancreas, which can cause blockage of the common bile duct. 5. Biliary atresia: A rare condition in which the common bile duct is missing or blocked, leading to liver damage. 6. Primary sclerosing cholangitis: A chronic inflammatory disease that affects the bile ducts, leading to scarring and blockage. 7. Caroli's disease: A rare genetic disorder that causes cysts to form in the bile ducts. Treatment for common bile duct diseases depends on the underlying cause and severity of the condition. It may include medications, endoscopic procedures, surgery, or a combination of these approaches.
Bile duct diseases refer to a group of medical conditions that affect the bile ducts, which are the tubes that carry bile from the liver to the small intestine. Bile is a greenish-yellow fluid that helps the body digest fats and absorb fat-soluble vitamins. When the bile ducts become damaged or blocked, it can lead to a buildup of bile in the liver or gallbladder, which can cause a range of symptoms and complications. Some common bile duct diseases include: 1. Cholangitis: Inflammation of the bile ducts that can be caused by a bacterial infection or other factors. 2. Cholecystitis: Inflammation of the gallbladder that can be caused by a blockage of the bile ducts or other factors. 3. Choledocholithiasis: A condition in which a stone forms in the bile ducts, which can cause blockages and other complications. 4. Primary sclerosing cholangitis: A chronic inflammatory disease that causes scarring and narrowing of the bile ducts. 5. Caroli's disease: A rare genetic disorder that affects the bile ducts and can cause blockages and infections. 6. Biliary atresia: A rare condition in which the bile ducts do not develop properly, leading to blockages and liver damage. Treatment for bile duct diseases depends on the underlying cause and severity of the condition. In some cases, medications or lifestyle changes may be sufficient to manage symptoms and prevent complications. In more severe cases, surgery or other medical procedures may be necessary to remove blockages or repair damaged bile ducts.
The common bile duct is a muscular tube that carries bile from the liver and gallbladder to the small intestine. It is about 10-12 cm long and is located in the upper right part of the abdomen, just below the liver. The common bile duct is formed by the union of the bile ducts from the liver and gallbladder, and it continues as the cystic duct, which empties into the small intestine at the ampulla of Vater. The common bile duct plays an important role in the digestion and absorption of fats and fat-soluble vitamins.
Bile ducts are a network of tubes that carry bile from the liver to the small intestine. Bile is a greenish-yellow fluid that is produced by the liver and helps to digest fats in the small intestine. The bile ducts begin in the liver and travel through the pancreas and then into the small intestine. There are two main types of bile ducts: the common bile duct and the hepatic ducts. The common bile duct is responsible for carrying bile from the liver and the gallbladder to the small intestine, while the hepatic ducts carry bile directly from the liver to the small intestine. Problems with the bile ducts can lead to a condition called cholecystitis, which is inflammation of the gallbladder, or cholangitis, which is inflammation of the bile ducts.
Gallstones are hard, solid masses that form in the gallbladder or bile ducts. They are typically composed of cholesterol, bilirubin, or a combination of both. Gallstones can cause a variety of symptoms, including abdominal pain, nausea, vomiting, and fever. In some cases, gallstones may not cause any symptoms and may be discovered incidentally during a routine medical examination. Treatment for gallstones depends on the size and number of stones, as well as the presence of symptoms. Small stones may be able to pass through the bile ducts on their own, while larger stones may require surgery or other medical interventions.
Common bile duct neoplasms refer to tumors or growths that develop in the common bile duct, which is a tube that carries bile from the liver to the small intestine. These neoplasms can be either benign or malignant, and they can cause a variety of symptoms, including abdominal pain, jaundice, and weight loss. Treatment options for common bile duct neoplasms depend on the type and stage of the tumor, as well as the overall health of the patient. Some possible treatments include surgery, chemotherapy, radiation therapy, and targeted therapy.
Cholangiopancreatography, Endoscopic Retrograde (ERCP) is a medical procedure used to diagnose and treat problems with the bile ducts and pancreas. It involves inserting a thin, flexible tube (endoscope) through the mouth and into the small intestine, where a dye is injected to highlight the bile ducts and pancreas on an X-ray. This allows doctors to see any blockages or abnormalities in the ducts and to take samples of tissue for further testing. ERCP is often used to diagnose and treat conditions such as gallstones, pancreatitis, and bile duct cancer. It is a minimally invasive procedure that is generally considered safe, although there are some risks associated with it.
Cholangiography is a medical imaging technique used to visualize the bile ducts and gallbladder. It involves the injection of a contrast dye into the bile ducts, which then appears on an X-ray or other imaging scan to create detailed images of the bile ducts and surrounding structures. This can help doctors diagnose conditions such as gallstones, bile duct blockages, and liver or pancreatic diseases. There are two main types of cholangiography: percutaneous cholangiography, which involves inserting a catheter through a small incision in the skin, and endoscopic retrograde cholangiopancreatography (ERCP), which involves inserting a flexible tube (endoscope) through the mouth and into the small intestine to access the bile ducts and pancreas.
Bile is a greenish-yellow fluid produced by the liver and stored in the gallbladder. It contains bile acids, bile pigments, electrolytes, and water. Bile plays a crucial role in the digestion and absorption of fats and fat-soluble vitamins in the small intestine. When food enters the small intestine, the gallbladder releases bile into the duodenum, the first part of the small intestine. Bile emulsifies fats, breaking them down into smaller droplets that can be more easily digested by enzymes in the small intestine. Bile also helps to neutralize stomach acid and aids in the absorption of fat-soluble vitamins. In the medical field, bile is often studied in relation to digestive disorders such as gallstones, bile duct obstruction, and liver disease. Abnormalities in bile production or function can lead to a range of symptoms, including abdominal pain, nausea, vomiting, and jaundice.
Choledocholithiasis is a medical condition characterized by the presence of gallstones (choleliths) in the common bile duct, which is a tube that carries bile from the liver to the small intestine. The condition can cause blockages in the bile duct, leading to a buildup of bile and pressure in the liver and gallbladder, which can cause pain, inflammation, and other symptoms. Symptoms of choledocholithiasis may include abdominal pain, nausea, vomiting, jaundice (yellowing of the skin and eyes), dark urine, and clay-colored stools. Diagnosis typically involves imaging tests such as ultrasound, CT scan, or MRI, which can detect the presence of gallstones in the bile duct. Treatment for choledocholithiasis may involve the use of medications to dissolve the gallstones, endoscopic retrograde cholangiopancreatography (ERCP) to remove the stones, or surgery to remove the gallbladder or bile duct. The choice of treatment depends on the size and location of the stones, as well as the severity of symptoms and other medical factors.
The extrahepatic bile ducts are a network of tubes that transport bile from the liver to the small intestine. They are located outside of the liver and include the common bile duct, the cystic duct, and the hepatic ducts. The common bile duct is the largest of the extrahepatic bile ducts and receives bile from both the right and left hepatic ducts. The cystic duct is a smaller duct that connects the gallbladder to the common bile duct. The hepatic ducts are a network of smaller ducts that collect bile from the liver and transport it to the common bile duct. The extrahepatic bile ducts play a crucial role in the digestion and absorption of fats and fat-soluble vitamins. Problems with the extrahepatic bile ducts can lead to a condition called cholangitis, which is characterized by inflammation of the bile ducts.
Cholestasis is a medical condition characterized by the impaired flow of bile in the liver and bile ducts. Bile is a greenish-yellow fluid that is produced by the liver and stored in the gallbladder. It plays a crucial role in the digestion and absorption of fats and fat-soluble vitamins. In cholestasis, the bile flow is either reduced or blocked, leading to the accumulation of bile in the liver and bile ducts. This can cause a range of symptoms, including jaundice (yellowing of the skin and whites of the eyes), itching, abdominal pain, and dark urine. Cholestasis can be caused by a variety of factors, including liver diseases such as viral hepatitis, drug-induced liver injury, and primary biliary cholangitis. It can also be a complication of pregnancy, known as obstetric cholestasis. Treatment for cholestasis depends on the underlying cause and may include medications to improve bile flow, dietary changes, and in severe cases, liver transplantation. Early diagnosis and treatment are important to prevent complications such as liver damage and liver failure.
Bile duct neoplasms refer to tumors that develop in the bile ducts, which are the tubes that carry bile from the liver to the small intestine. These tumors can be either benign or malignant, and they can occur in any part of the bile duct system, including the intrahepatic bile ducts (which are located within the liver), the extrahepatic bile ducts (which are located outside the liver), and the ampulla of Vater (which is the point where the common bile duct and the main pancreatic duct join). Bile duct neoplasms can present with a variety of symptoms, depending on the location and size of the tumor. Some common symptoms include jaundice (yellowing of the skin and eyes), abdominal pain, weight loss, and fever. Diagnosis typically involves imaging studies such as ultrasound, CT scan, or MRI, as well as biopsy to confirm the presence of cancer cells. Treatment for bile duct neoplasms depends on the type and stage of the tumor, as well as the overall health of the patient. Options may include surgery, chemotherapy, radiation therapy, or a combination of these approaches. The prognosis for bile duct neoplasms varies widely, depending on the specific type and stage of the tumor, as well as the patient's age, overall health, and response to treatment.
Cholestasis, Extrahepatic refers to a condition in which bile flow is impaired outside of the liver. This can occur due to a variety of factors, including blockages in the bile ducts, damage to the bile ducts, or problems with the muscles that control the flow of bile. Symptoms of extrahepatic cholestasis may include jaundice (yellowing of the skin and eyes), itching, abdominal pain, and dark urine. Treatment for extrahepatic cholestasis typically involves addressing the underlying cause of the blockage or damage, such as surgery to remove a tumor or medication to treat an infection. In some cases, a procedure called a biliary stent may be used to help restore bile flow.
Cholecystectomy, Laparoscopic is a surgical procedure that involves removing the gallbladder through small incisions in the abdomen using a laparoscope. The laparoscope is a thin, tube-like instrument that is inserted through the incisions and equipped with a camera that allows the surgeon to view the inside of the abdomen on a video monitor. The surgeon uses specialized instruments to remove the gallbladder and close the incisions. Laparoscopic cholecystectomy is a minimally invasive procedure that typically results in less pain, a shorter hospital stay, and a faster recovery time compared to traditional open cholecystectomy. It is commonly performed to treat gallstones, inflammation of the gallbladder (cholecystitis), and other conditions that affect the gallbladder.
Cholecystectomy is a surgical procedure in which the gallbladder is removed from the body. The gallbladder is a small, pear-shaped organ located in the upper right abdomen, just below the liver. It stores bile, a digestive fluid produced by the liver, and releases it into the small intestine when needed to help digest fats. There are several reasons why a cholecystectomy may be performed, including: 1. Gallstones: Gallstones are hard, pebble-like deposits that can form in the gallbladder. If they become stuck in the bile ducts, they can cause pain, inflammation, and other complications. 2. Cholecystitis: Cholecystitis is an inflammation of the gallbladder that can be caused by gallstones or other factors. It can cause severe pain and other symptoms. 3. Gallbladder cancer: In rare cases, a cholecystectomy may be performed to remove a gallbladder that has cancerous growths. Cholecystectomy can be performed using either an open surgical technique or laparoscopic surgery. In open surgery, a large incision is made in the abdomen to access the gallbladder. In laparoscopic surgery, several small incisions are made in the abdomen, and a thin, tube-like instrument called a laparoscope is inserted to view the inside of the abdomen and perform the surgery. After a cholecystectomy, the patient will typically stay in the hospital for a few days to recover. They will need to follow a special diet and take medications to prevent infection and manage pain. Most people are able to return to their normal activities within a few weeks.
Bile acids and salts are a group of compounds that are produced in the liver and secreted into the small intestine. They play a crucial role in the digestion and absorption of dietary fats and fat-soluble vitamins. Bile acids are synthesized from cholesterol in the liver and are stored in the gallbladder. When food enters the small intestine, the gallbladder releases bile into the duodenum, the first part of the small intestine. Bile acids emulsify fats, breaking them down into smaller droplets that can be more easily digested by enzymes in the small intestine. Bile salts are the primary components of bile and are responsible for the emulsification of fats. They are also involved in the absorption of fat-soluble vitamins, such as vitamins A, D, E, and K. In the medical field, bile acids and salts are often studied in relation to digestive disorders, such as gallstones, liver disease, and bile duct obstruction. They are also used in the treatment of certain conditions, such as bile acid diarrhea and cholestatic liver disease.
Intrahepatic bile ducts are the small tubes that carry bile from the liver to the small intestine. They are located within the liver and are responsible for transporting bile from the liver cells (hepatocytes) to the bile ducts that lead to the small intestine. Bile is a greenish-yellow fluid that is produced by the liver and helps to digest fats in the small intestine. Intrahepatic bile ducts are an important part of the digestive system and any problems with them can lead to a condition called cholangitis, which is an inflammation of the bile ducts.
Jaundice, obstructive is a medical condition characterized by the yellowing of the skin and whites of the eyes (jaundice) due to the buildup of bilirubin in the body. Bilirubin is a yellow pigment produced when red blood cells are broken down and is normally processed by the liver and excreted in the bile. Obstructive jaundice occurs when there is a blockage in the bile ducts, which are the tubes that carry bile from the liver to the small intestine. This blockage can be caused by a variety of factors, including gallstones, tumors, inflammation, or injury to the bile ducts. When bile cannot flow freely from the liver, it builds up in the liver and eventually leaks into the bloodstream, causing jaundice. Other symptoms of obstructive jaundice may include abdominal pain, nausea, vomiting, fever, and dark urine. Treatment for obstructive jaundice depends on the underlying cause and may include medications, endoscopic procedures, surgery, or radiation therapy. Early diagnosis and treatment are important to prevent complications and improve outcomes.
Cholangiopancreatography, Magnetic Resonance (MRCP) is a medical imaging technique that uses magnetic resonance imaging (MRI) to visualize the bile ducts and pancreas. It is a non-invasive procedure that does not require the use of contrast dye or radiation. During an MRCP, a patient lies on a table that is moved into a large, powerful magnet. The magnet creates a strong magnetic field that aligns the hydrogen atoms in the body. Radiofrequency pulses are then sent through the body, which cause the hydrogen atoms to resonate and produce signals that are detected by the MRI machine. These signals are then used to create detailed images of the bile ducts and pancreas. MRCP is often used to diagnose and evaluate conditions that affect the bile ducts and pancreas, such as gallstones, bile duct strictures, and pancreatic cancer. It can also be used to monitor the effectiveness of treatments for these conditions. MRCP is a safe and effective imaging technique that is well-tolerated by most patients.
Cholangitis is an inflammation of the bile ducts, which are the tubes that carry bile from the liver to the small intestine. It can be caused by a variety of factors, including bacterial infections, viral infections, and blockages in the bile ducts. Symptoms of cholangitis may include fever, abdominal pain, nausea, vomiting, and jaundice (yellowing of the skin and eyes). Treatment typically involves antibiotics to treat the underlying cause of the inflammation, as well as supportive care to manage symptoms and prevent complications. In severe cases, surgery may be necessary to remove blockages or damaged bile ducts.
The cystic duct is a small tube that carries bile from the gallbladder to the common bile duct, which then leads to the small intestine. It is approximately 1 to 2 inches long and is located in the abdomen, behind the liver. The cystic duct is lined with a smooth muscle layer that helps to regulate the flow of bile. In some cases, the cystic duct may become blocked, leading to a condition called cholecystitis, which can cause inflammation and pain in the gallbladder.
Cholelithiasis is a medical condition characterized by the formation of gallstones in the gallbladder. Gallstones are hard, solid masses that can range in size from a grain of sand to a golf ball. They are typically composed of cholesterol, calcium, or a combination of both. Cholelithiasis can cause a variety of symptoms, including abdominal pain, nausea, vomiting, and fever. In some cases, gallstones may cause no symptoms at all and may only be discovered incidentally during a routine medical examination. If left untreated, cholelithiasis can lead to complications such as cholecystitis (inflammation of the gallbladder), pancreatitis (inflammation of the pancreas), and gallbladder cancer. Treatment options for cholelithiasis include medication, endoscopic procedures, and surgery.
The Ampulla of Vater, also known as the hepatopancreatic ampulla or the hepatopancreatic duct, is a small, funnel-shaped structure located at the confluence of the bile duct and the main pancreatic duct. It is situated in the head of the pancreas, just inferior to the duodenum, and is surrounded by the ampulla of Vater's gland, which is a group of specialized cells that produce mucus to lubricate the passage of bile and pancreatic juice through the ampulla. The ampulla of Vater plays a critical role in the digestive process by allowing bile and pancreatic juice to mix and enter the duodenum, where they help to break down and digest food. Disorders of the ampulla of Vater can lead to a variety of digestive problems, including jaundice, abdominal pain, and malabsorption. Some common conditions that affect the ampulla of Vater include ampullary cancer, pancreatitis, and bile duct stones.
Biliary tract diseases refer to a group of medical conditions that affect the biliary system, which is responsible for producing, storing, and transporting bile from the liver to the small intestine. The biliary system includes the liver, gallbladder, bile ducts, and the ampulla of Vater. Biliary tract diseases can be classified into two main categories: obstructive and non-obstructive. Obstructive biliary tract diseases occur when there is a blockage in the bile ducts, preventing bile from flowing normally. Non-obstructive biliary tract diseases, on the other hand, do not involve a blockage but can still cause problems with bile flow. Some common biliary tract diseases include: 1. Cholecystitis: Inflammation of the gallbladder. 2. Cholangitis: Inflammation of the bile ducts. 3. Cholangiocarcinoma: Cancer of the bile ducts. 4. Choledocholithiasis: Presence of stones in the bile ducts. 5. Pancreatitis: Inflammation of the pancreas, which can affect the bile ducts. 6. Primary sclerosing cholangitis: Chronic inflammation and scarring of the bile ducts. Biliary tract diseases can cause a range of symptoms, including abdominal pain, jaundice (yellowing of the skin and eyes), nausea, vomiting, and fever. Treatment options depend on the specific type and severity of the disease, and may include medications, surgery, or other interventions.
The biliary tract is a system of organs and tubes that are responsible for producing, storing, and transporting bile. Bile is a greenish-yellow fluid that is produced by the liver and stored in the gallbladder. It contains bile salts, which help to break down fats in the small intestine. The biliary tract includes the liver, gallbladder, bile ducts, and the common bile duct. The liver produces bile and releases it into the bile ducts, which carry it to the gallbladder for storage. When food containing fats enters the small intestine, the gallbladder releases bile into the common bile duct, which then carries it to the small intestine to help with fat digestion. Diseases or problems that affect the biliary tract can include gallstones, which are hard deposits that can form in the gallbladder or bile ducts, and bile duct cancer, which is a rare type of cancer that affects the bile ducts. Other conditions that can affect the biliary tract include liver disease, pancreatitis, and infections.
Pancreatitis is a medical condition characterized by inflammation of the pancreas, a gland located in the abdomen behind the stomach. The pancreas plays a crucial role in the digestive system by producing enzymes that help break down food and hormones that regulate blood sugar levels. There are two main types of pancreatitis: acute and chronic. Acute pancreatitis is a sudden and severe inflammation of the pancreas that usually lasts for a few days to a few weeks. It can be caused by a variety of factors, including excessive alcohol consumption, gallstones, infections, and certain medications. Symptoms of acute pancreatitis may include severe abdominal pain, nausea, vomiting, fever, and elevated levels of certain enzymes in the blood. Chronic pancreatitis is a long-term inflammation of the pancreas that can develop over time due to repeated episodes of acute pancreatitis, long-term alcohol abuse, or other factors. It can cause permanent damage to the pancreas, leading to problems with digestion and blood sugar control. Symptoms of chronic pancreatitis may include abdominal pain, weight loss, malnutrition, and diabetes. Treatment for pancreatitis depends on the severity and underlying cause of the condition. In some cases, hospitalization may be necessary to manage pain, prevent complications, and provide supportive care. In other cases, lifestyle changes such as quitting smoking and reducing alcohol consumption may be recommended to prevent future episodes. Medications and surgery may also be used to treat specific causes of pancreatitis, such as gallstones or infections.
A choledochal cyst is a rare congenital malformation of the bile ducts that occurs during fetal development. It is characterized by the abnormal dilation of the bile ducts, which can lead to the formation of a cyst or sac-like structure in the liver or bile ducts. There are several types of choledochal cysts, classified based on their location and anatomy. The most common type is type I, which involves dilation of the common bile duct. Other types include type II, which involves dilation of the intrahepatic bile ducts; type III, which involves dilation of both the common bile duct and the intrahepatic bile ducts; type IV, which involves dilation of the cystic duct; and type V, which involves dilation of the extrahepatic bile ducts. Choledochal cysts can cause a variety of symptoms, including abdominal pain, jaundice, and liver function abnormalities. Treatment typically involves surgical removal of the cyst, although the specific approach may vary depending on the type and location of the cyst. In some cases, additional procedures may be necessary to address complications or underlying liver disease.
A biliary fistula is a abnormal connection between the bile ducts and another body cavity or surface, such as the stomach, small intestine, colon, or skin. This can occur due to various medical conditions, including trauma, surgery, liver disease, or cancer. Bile is a fluid produced by the liver that helps with digestion and absorption of fats. When a biliary fistula occurs, bile can leak out of the bile ducts and into the surrounding tissue or other body cavities, leading to a range of symptoms such as abdominal pain, jaundice, nausea, vomiting, and diarrhea. Treatment for biliary fistulas depends on the underlying cause and severity of the condition. In some cases, the fistula may close on its own over time. However, in more severe cases, surgery may be necessary to repair or remove the fistula and prevent complications such as infection or abscess formation.
Biliary tract surgical procedures refer to a range of surgical interventions that are performed to treat conditions affecting the biliary tract, which includes the liver, gallbladder, bile ducts, and pancreas. These procedures may be performed to remove or repair damaged tissue, to remove obstructions or tumors, or to manage complications from other medical conditions. Some common biliary tract surgical procedures include: 1. Cholecystectomy: This is the surgical removal of the gallbladder, which is a small organ that stores bile produced by the liver. 2. Bile duct exploration: This procedure involves exploring the bile ducts to identify and remove obstructions or tumors. 3. Pancreaticoduodenectomy: This is a major surgical procedure that involves removing part of the pancreas, the duodenum (the first part of the small intestine), and the bile ducts. 4. Liver transplantation: This is a surgical procedure in which a healthy liver is transplanted into a person with liver failure or liver cancer. 5. Endoscopic retrograde cholangiopancreatography (ERCP): This is a minimally invasive procedure in which a flexible tube is inserted through the mouth and into the bile ducts to diagnose and treat conditions such as gallstones or bile duct obstructions. These procedures may be performed using a variety of techniques, including laparoscopic surgery, robotic surgery, and open surgery, depending on the specific condition being treated and the preferences of the surgeon and patient.
A choledochostomy is a surgical procedure in which a small opening (stoma) is created in the wall of the common bile duct to allow bile to drain from the liver and gallbladder into a plastic or rubber tube called a stent. The stent is then inserted into the small intestine to help the body digest fats. This procedure is typically performed when there is a blockage in the common bile duct, which can cause jaundice (yellowing of the skin and eyes) and other complications. The blockage may be caused by a tumor, inflammation, or other conditions. A choledochostomy is usually a temporary solution until the underlying cause of the blockage can be treated or until the patient is ready for more definitive surgery, such as a bile duct bypass or a liver transplant. The stoma is typically closed during a follow-up surgery once the blockage has been resolved.
Adenoma of the bile duct is a benign (non-cancerous) growth that develops in the bile ducts, which are the tubes that carry bile from the liver to the small intestine. Bile is a fluid that helps to digest fats in the small intestine. Adenomas of the bile duct can occur anywhere along the length of the bile ducts, but they are most commonly found in the common bile duct, which is the main channel that carries bile from the liver to the small intestine. Symptoms of adenoma of the bile duct may include jaundice (yellowing of the skin and whites of the eyes), abdominal pain, and fever. In some cases, an adenoma of the bile duct may cause no symptoms at all. Treatment for adenoma of the bile duct typically involves surgery to remove the growth. In some cases, a procedure called endoscopic retrograde cholangiopancreatography (ERCP) may be used to remove the adenoma through the mouth using a flexible tube with a camera and tools at the end. If the adenoma is large or has caused complications, surgery may be necessary to remove the affected portion of the bile duct.
Cholecystitis is a medical condition characterized by inflammation of the gallbladder. The gallbladder is a small organ located in the upper right abdomen that stores bile, a digestive fluid produced by the liver. When the gallbladder becomes inflamed, it can cause pain, fever, nausea, and vomiting. Cholecystitis can be caused by a variety of factors, including the presence of gallstones, infections, and injury to the gallbladder. Gallstones are hard, pebble-like deposits that can form in the gallbladder and block the flow of bile. This can lead to inflammation and infection of the gallbladder, which can cause cholecystitis. Treatment for cholecystitis typically involves antibiotics to treat any infections, pain medication to relieve symptoms, and in severe cases, surgery to remove the inflamed gallbladder. It is important to seek medical attention if you experience symptoms of cholecystitis, as untreated cholecystitis can lead to serious complications, such as perforation of the gallbladder or infection of the surrounding tissues.
Imino acids are a type of amino acid that have a nitrogen atom (imino group) bonded to the alpha carbon atom of the amino acid side chain. They are also known as alpha-imino acids or alpha-aminoiminocarboxylic acids. There are 20 amino acids that are commonly found in proteins, and 16 of them are imino acids. The remaining four are non-imino acids, which do not have an imino group in their side chains. Imino acids play important roles in the structure and function of proteins, and they are involved in many biological processes, including metabolism, enzyme catalysis, and signal transduction.
Gallbladder diseases refer to a range of medical conditions that affect the gallbladder, a small organ located in the upper right abdomen that stores bile produced by the liver. Some common gallbladder diseases include: 1. Cholecystitis: Inflammation of the gallbladder, often caused by a blockage of the bile ducts. 2. Cholelithiasis: Formation of gallstones, which can cause blockages in the bile ducts and lead to inflammation of the gallbladder. 3. Gallbladder polyps: Small growths on the inner lining of the gallbladder. 4. Gallbladder cancer: Rare, but potentially life-threatening cancer of the gallbladder. 5. Acute cholecystitis: A more severe form of cholecystitis that requires immediate medical attention. 6. Chronic cholecystitis: A long-term inflammation of the gallbladder that can lead to scarring and thickening of the gallbladder wall. 7. Biliary colic: Severe pain in the upper right abdomen that can be caused by gallstones blocking the bile ducts. 8. Gallbladder removal surgery (cholecystectomy): A surgical procedure to remove the gallbladder when it becomes diseased or is causing problems.
Jaundice is a medical condition characterized by yellowing of the skin and whites of the eyes (icterus) due to an excess of bilirubin in the blood. Bilirubin is a yellowish-brown pigment produced when red blood cells are broken down in the liver. Jaundice can be caused by a variety of factors, including liver disease, gallbladder disease, infections, blockages in the bile ducts, and certain medications. It can also be a sign of a more serious underlying condition, such as liver cancer or cirrhosis. The symptoms of jaundice may include yellowing of the skin and whites of the eyes, dark urine, clay-colored stools, fatigue, weakness, abdominal pain, and loss of appetite. Treatment for jaundice depends on the underlying cause and may include medications, surgery, or other interventions.
Adenomyoma is a benign (non-cancerous) tumor that develops in the muscle tissue of the uterus. It is a type of uterine fibroid, which is a common benign growth in women of reproductive age. Adenomyoma is characterized by the presence of glandular tissue (adenoma) within the muscle fibers of the uterus (myoma). This can cause the uterus to enlarge and may cause symptoms such as heavy bleeding, pain, and discomfort during menstruation. Adenomyoma is typically diagnosed through imaging tests such as ultrasound or MRI, and treatment options may include medication, surgery, or other interventions depending on the severity of symptoms and the size and location of the tumor.
Technetium Tc 99m Disofenin is a radiopharmaceutical used in medical imaging to diagnose and monitor liver function. It is a compound that contains the radioactive isotope Technetium-99m (Tc-99m) and the chelating agent Disofenin, which is a synthetic estrogen-like compound that binds to liver cells. When injected into the bloodstream, Tc-99m Disofenin is taken up by the liver and can be imaged using a gamma camera to assess liver function and detect any abnormalities or damage to the liver. It is commonly used to diagnose liver diseases such as cirrhosis, hepatitis, and liver cancer.
Pathologic dilatation refers to the abnormal enlargement or widening of a body structure, such as a blood vessel, organ, or tube, beyond its normal size. This can be caused by a variety of factors, including injury, disease, or genetic abnormalities. Pathologic dilatation can be a sign of underlying health problems and may require medical intervention to prevent further complications. It is important to note that not all dilatation is considered pathologic, as some degree of dilation may be normal or even beneficial in certain situations.
Gallbladder neoplasms refer to abnormal growths or tumors that develop in the gallbladder, a small organ located in the upper right part of the abdomen. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Benign gallbladder neoplasms include polyps, which are small, non-cancerous growths that can develop on the lining of the gallbladder. These polyps are usually asymptomatic and are often discovered incidentally during imaging studies for other conditions. Malignant gallbladder neoplasms, on the other hand, are less common but more serious. These include gallbladder cancer, which can be either primary (occurring in the gallbladder) or secondary (occurring as a result of cancer that has spread from another part of the body to the gallbladder). Symptoms of gallbladder neoplasms may include abdominal pain, jaundice (yellowing of the skin and eyes), nausea, vomiting, and weight loss. Diagnosis typically involves imaging studies such as ultrasound, CT scan, or MRI, as well as biopsy to confirm the presence of a neoplasm. Treatment for gallbladder neoplasms depends on the type and stage of the tumor, as well as the overall health of the patient. Options may include surgery to remove the affected organ, chemotherapy, radiation therapy, or a combination of these approaches.
Intrahepatic cholestasis is a medical condition characterized by the blockage of bile flow within the liver. Bile is a fluid produced by the liver that helps to digest fats and absorb fat-soluble vitamins. When bile flow is blocked within the liver, it can lead to a buildup of bile acids and other substances in the bloodstream, which can cause a range of symptoms and complications. The most common cause of intrahepatic cholestasis is pregnancy, although it can also occur in non-pregnant individuals. Other potential causes include viral infections, drug reactions, and inherited metabolic disorders. Symptoms of intrahepatic cholestasis may include itching, fatigue, abdominal pain, and jaundice (yellowing of the skin and eyes). In severe cases, the condition can lead to liver damage and even liver failure. Treatment for intrahepatic cholestasis typically involves managing symptoms and addressing any underlying causes. In some cases, medications may be prescribed to help increase bile flow or reduce itching. In severe cases, hospitalization and other more aggressive treatments may be necessary.
Cholecystitis, acute is a medical condition characterized by inflammation of the gallbladder. It is usually caused by the presence of gallstones in the gallbladder, which can block the flow of bile and lead to infection and inflammation. Symptoms of acute cholecystitis may include abdominal pain, fever, nausea, vomiting, and jaundice. Treatment typically involves antibiotics to treat any infection and surgery to remove the gallbladder (cholecystectomy).
Sphincter of Oddi Dysfunction (SOD) is a condition in which the muscles of the sphincter of Oddi, a muscular ring that controls the flow of bile and pancreatic juice from the pancreas and liver into the small intestine, do not function properly. This can lead to a backup of these digestive fluids in the bile ducts and pancreatic ducts, causing a range of symptoms such as abdominal pain, nausea, vomiting, and jaundice. SOD can be caused by a variety of factors, including inflammation, tumors, or damage to the sphincter muscles. It is typically diagnosed through a combination of medical history, physical examination, and imaging studies such as endoscopic retrograde cholangiopancreatography (ERCP). Treatment for SOD may include medications, endoscopic procedures, or surgery, depending on the underlying cause and severity of the symptoms.
Cholecystolithiasis is a medical condition characterized by the presence of one or more stones in the gallbladder. These stones are typically made up of cholesterol, calcium, or a combination of both. The condition is also known as gallstones. Cholecystolithiasis can cause a range of symptoms, including abdominal pain, nausea, vomiting, and fever. In some cases, the stones may block the bile duct, leading to jaundice and other complications. Treatment for cholecystolithiasis typically involves surgery to remove the gallbladder and any stones that are present. In some cases, medications may be used to dissolve the stones or to alleviate symptoms. It is important to seek medical attention if you suspect you may have cholecystolithiasis, as untreated gallstones can lead to serious complications.
Bilirubin is a yellowish pigment that is produced when red blood cells are broken down in the body. It is primarily produced in the liver and is then excreted in the bile, which is released into the small intestine. Bilirubin is an important part of the body's waste removal system and helps to remove old red blood cells from the bloodstream. In the medical field, bilirubin levels are often measured as part of a routine blood test. High levels of bilirubin in the blood can be a sign of liver disease, such as hepatitis or cirrhosis, or of problems with the gallbladder or bile ducts. Bilirubin levels can also be affected by certain medications, infections, or genetic disorders. Low levels of bilirubin can be a sign of anemia or other blood disorders.
Pancreatic diseases refer to a group of medical conditions that affect the pancreas, a gland located in the abdomen behind the stomach. The pancreas plays a vital role in the digestive and endocrine systems, producing enzymes that help break down food and hormones that regulate blood sugar levels. Pancreatic diseases can be classified into two main categories: exocrine pancreatic diseases and endocrine pancreatic diseases. Exocrine pancreatic diseases affect the pancreas' ability to produce digestive enzymes, leading to malabsorption of nutrients and digestive problems. Examples of exocrine pancreatic diseases include chronic pancreatitis, cystic fibrosis, and pancreatic cancer. Endocrine pancreatic diseases affect the pancreas' ability to produce hormones, leading to imbalances in blood sugar levels. Examples of endocrine pancreatic diseases include type 1 diabetes, type 2 diabetes, and pancreatic neuroendocrine tumors. Pancreatic diseases can be challenging to diagnose and treat, as they often present with non-specific symptoms and can affect multiple organ systems. Treatment options depend on the specific disease and may include medications, surgery, or other interventions.
Postoperative complications are adverse events that occur after a surgical procedure. They can range from minor issues, such as bruising or discomfort, to more serious problems, such as infection, bleeding, or organ damage. Postoperative complications can occur for a variety of reasons, including surgical errors, anesthesia errors, infections, allergic reactions to medications, and underlying medical conditions. They can also be caused by factors such as poor nutrition, dehydration, and smoking. Postoperative complications can have serious consequences for patients, including prolonged hospital stays, additional surgeries, and even death. Therefore, it is important for healthcare providers to take steps to prevent postoperative complications and to promptly recognize and treat them if they do occur.
Cholecystostomy is a surgical procedure in which an opening (stoma) is created in the wall of the gallbladder to allow the release of bile. This procedure is typically performed when the gallbladder becomes blocked or inflamed, a condition known as cholecystitis. During a cholecystostomy, a surgeon will make a small incision in the abdomen and insert a tube (called a stent) through the wall of the gallbladder and into the small intestine. The stent remains in place permanently, allowing bile to flow from the gallbladder into the intestine. Cholecystostomy is often used as a temporary measure until the underlying cause of the cholecystitis can be treated, such as the removal of a gallstone or the repair of a damaged bile duct. It can also be used as a permanent solution for patients who are unable to undergo more invasive surgery, such as cholecystectomy.
Bile reflux is a condition in which bile, a digestive fluid produced by the liver, flows back up from the small intestine into the stomach or even the esophagus. This can cause a range of symptoms, including heartburn, chest pain, difficulty swallowing, and a sour taste in the mouth. Bile reflux can be caused by a variety of factors, including a hiatal hernia, a condition in which the upper part of the stomach moves up into the chest, or damage to the muscles in the lower esophagus that normally prevent stomach contents from flowing back up. It can also be caused by certain medications, such as certain blood pressure medications, or by certain medical procedures, such as surgery for obesity. Treatment for bile reflux typically involves lifestyle changes, such as avoiding certain foods and beverages that can trigger symptoms, and medications to reduce acid production in the stomach. In some cases, surgery may be necessary to correct the underlying cause of the reflux.
Liver Cirrhosis, Experimental refers to a condition in which the liver becomes scarred and damaged due to various experimental procedures or treatments. This can occur in laboratory animals or humans who are undergoing medical research or clinical trials. Experimental liver cirrhosis can be induced by various methods, such as administering toxins, viruses, or other substances that cause liver damage. The purpose of such experiments is to study the pathophysiology of liver disease and to develop new treatments or therapies. The severity and extent of liver damage in experimental liver cirrhosis can vary depending on the type and duration of the experimental procedure. In some cases, the liver damage may be reversible, while in others, it may be irreversible and lead to liver failure or death. It is important to note that experimental liver cirrhosis is a controlled and regulated process that is conducted under strict ethical guidelines to minimize harm to the animals or humans involved.
Pathologic constriction refers to a medical condition in which a blood vessel or other tubular structure becomes narrowed or blocked, leading to reduced blood flow or obstruction of the flow of other substances through the vessel. This can occur due to a variety of factors, including inflammation, scarring, abnormal growths, or the presence of a foreign object. Pathologic constriction can have serious consequences, depending on the location and severity of the constriction, and may require medical intervention to treat.
Catheterization is a medical procedure in which a thin, flexible tube called a catheter is inserted into a body cavity or blood vessel to allow access for medical treatment or diagnostic testing. The catheter is typically inserted through a small incision or puncture in the skin and guided to its destination using imaging guidance such as X-rays or ultrasound. There are many different types of catheterizations, including: 1. Urinary catheterization: This involves inserting a catheter into the bladder to drain urine. 2. Venous catheterization: This involves inserting a catheter into a vein to allow for the administration of medication, blood draws, or other treatments. 3. Arterial catheterization: This involves inserting a catheter into an artery to allow for the measurement of blood pressure or the administration of medication. 4. Central venous catheterization: This involves inserting a catheter into a large vein near the heart to allow for long-term access to the bloodstream for treatments such as chemotherapy or fluid replacement. Catheterization is a common medical procedure that can be performed in a variety of settings, including hospitals, clinics, and ambulatory care centers. It is typically performed by a trained healthcare professional, such as a nurse or physician, and is generally considered safe when performed properly. However, like any medical procedure, catheterization carries some risks, including infection, bleeding, and damage to surrounding tissues.
Duodenal diseases refer to medical conditions that affect the duodenum, which is the first part of the small intestine. The duodenum is responsible for receiving and mixing food from the stomach with digestive enzymes and bile from the liver and gallbladder. Some common duodenal diseases include: 1. Duodenal ulcers: These are sores that develop in the lining of the duodenum or the stomach. They are often caused by the bacteria Helicobacter pylori and can lead to bleeding, pain, and other complications. 2. Duodenal diverticulosis: This is a condition in which small pouches or sacs form in the wall of the duodenum. It is usually asymptomatic but can cause complications such as bleeding, infection, and blockage. 3. Duodenal cancer: This is a rare type of cancer that develops in the cells lining the duodenum. It can cause symptoms such as abdominal pain, weight loss, and changes in bowel habits. 4. Duodenal strictures: These are narrowing or blockages in the duodenum that can be caused by inflammation, scarring, or other factors. They can lead to symptoms such as abdominal pain, vomiting, and difficulty swallowing. 5. Duodenal polyps: These are small growths that develop on the lining of the duodenum. Most are harmless, but some can be precancerous or lead to bleeding. Treatment for duodenal diseases depends on the specific condition and its severity. It may include medications, lifestyle changes, endoscopic procedures, or surgery.
Cholangiocarcinoma is a type of cancer that develops in the bile ducts, which are the tubes that carry bile from the liver to the small intestine. It is a rare but aggressive form of cancer that can occur in the liver, bile ducts in the liver, or the bile ducts outside the liver. Cholangiocarcinoma can be classified into two main types: intrahepatic cholangiocarcinoma (which occurs within the liver) and extrahepatic cholangiocarcinoma (which occurs outside the liver, in the bile ducts that connect the liver to the small intestine). Symptoms of cholangiocarcinoma may include jaundice (yellowing of the skin and eyes), abdominal pain, weight loss, fever, and fatigue. Diagnosis typically involves imaging tests such as ultrasound, CT scan, or MRI, as well as a biopsy to confirm the presence of cancer cells. Treatment for cholangiocarcinoma may include surgery, chemotherapy, radiation therapy, or a combination of these approaches. The prognosis for cholangiocarcinoma depends on several factors, including the stage of the cancer at diagnosis, the location of the tumor, and the patient's overall health.
Duodenal neoplasms refer to abnormal growths or tumors that develop in the duodenum, which is the first part of the small intestine. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Duodenal neoplasms can present with a variety of symptoms, including abdominal pain, nausea, vomiting, weight loss, and jaundice. The diagnosis of duodenal neoplasms typically involves a combination of imaging studies, such as endoscopy and CT scans, and biopsy to confirm the presence of cancer cells. Treatment for duodenal neoplasms depends on the type and stage of the cancer, as well as the patient's overall health. Options may include surgery, chemotherapy, radiation therapy, or a combination of these approaches. Early detection and treatment are important for improving outcomes and reducing the risk of complications.
In the medical field, "calculi" refers to solid masses or stones that form in the urinary tract or other organs. The most common type of calculi are kidney stones, which can form in the kidneys, ureters, or bladder. Kidney stones are typically composed of minerals such as calcium, oxalate, or phosphate, and can vary in size from a grain of sand to a golf ball. They can cause severe pain, blood in the urine, and other symptoms, and may require medical intervention to remove. Other types of calculi can form in the gallbladder (gallstones), bile ducts (cholecystolithiasis), or pancreas (pancreatic calculi). These calculi can also cause serious health problems if left untreated.
Liver Cirrhosis, Biliary refers to a condition where the liver becomes scarred and damaged due to chronic inflammation and scarring of the bile ducts. Bile ducts are responsible for carrying bile, a fluid produced by the liver, from the liver to the small intestine. The most common cause of liver cirrhosis, biliary is chronic inflammation of the bile ducts, which can be caused by various factors such as infections, autoimmune disorders, and inherited genetic conditions. Other causes include liver damage due to alcohol, viral hepatitis, and exposure to toxins. Symptoms of liver cirrhosis, biliary may include jaundice (yellowing of the skin and eyes), abdominal pain, fatigue, loss of appetite, and weight loss. In severe cases, it can lead to liver failure, which can be life-threatening. Treatment for liver cirrhosis, biliary depends on the underlying cause and the severity of the condition. In some cases, medications or surgery may be used to treat the underlying cause. In other cases, supportive care may be provided to manage symptoms and prevent complications such as infections and bleeding. In severe cases, a liver transplant may be necessary.
Ascaridida is a subclass of nematodes, which are roundworms, that includes several species of intestinal parasites that can cause human and animal infections. The most common species of ascaridids that affect humans are Ascaris lumbricoides and Toxocara canis. Ascaris lumbricoides is a large intestinal roundworm that can cause ascariasis, a common parasitic infection that affects millions of people worldwide, particularly in developing countries. The symptoms of ascariasis can include abdominal pain, diarrhea, nausea, and vomiting. In severe cases, the worms can migrate to the lungs, causing coughing and difficulty breathing. Toxocara canis is a roundworm that can cause toxocariasis, a parasitic infection that is most commonly found in dogs but can also affect humans. The eggs of Toxocara canis can be transmitted to humans through contact with contaminated soil or surfaces, and the larvae can migrate to various organs in the body, including the brain, lungs, and eyes. Symptoms of toxocariasis can include fever, coughing, and eye inflammation. Treatment for ascaridida infections typically involves the use of anthelmintic drugs, which are medications that kill or expel the worms from the body. Prevention measures include proper hygiene, avoiding contact with contaminated soil or surfaces, and regular deworming of pets.
Lithiasis is a medical term that refers to the presence of one or more stones (also known as calculi) in the urinary tract. These stones can form in the kidneys, ureters, bladder, or urethra and can cause a range of symptoms, including pain, blood in the urine, frequent urination, and difficulty urinating. The most common type of lithiasis is kidney stone disease, which affects millions of people worldwide. Kidney stones are typically composed of minerals such as calcium, oxalate, or phosphate, and can vary in size from a grain of sand to a golf ball. Treatment for lithiasis depends on the size and location of the stone, as well as the severity of symptoms. Small stones may pass through the urinary tract on their own, while larger stones may require medical intervention such as shock wave lithotripsy, surgery, or medication to dissolve the stone. Prevention of lithiasis involves maintaining a healthy diet and staying hydrated, as well as managing underlying medical conditions such as high blood pressure or diabetes.
Hepatopulmonary syndrome (HPS) is a rare complication of advanced liver disease characterized by the development of abnormal blood vessels in the lungs that can lead to shortness of breath, fatigue, and other symptoms. HPS occurs when the liver is unable to properly remove toxins from the blood, leading to the formation of new blood vessels in the lungs that can cause the lungs to become overfilled with fluid and air. This can lead to a decrease in the amount of oxygen that is able to reach the body's tissues, resulting in symptoms such as shortness of breath, fatigue, and swelling in the legs and ankles. HPS is most commonly seen in people with cirrhosis, a condition in which the liver becomes scarred and unable to function properly. Treatment for HPS typically involves addressing the underlying cause of the liver disease and managing the symptoms of the condition.
Colic is a medical condition characterized by abdominal pain or discomfort that is recurrent and severe. It is commonly associated with infants, particularly those under six months of age, but can also occur in adults and older children. In infants, colic typically presents with episodes of crying, fussiness, and restlessness that last for several hours at a time, usually in the late afternoon or evening. The crying is often accompanied by a red face, clenched fists, and a distended abdomen. The exact cause of colic in infants is not fully understood, but it is believed to be related to factors such as gas buildup, digestive issues, and sensitivity to certain foods. Treatment for colic in infants may include changes in feeding habits, such as switching to a different formula or introducing solid foods, as well as soothing techniques such as swaddling and rocking. In adults and older children, colic can be caused by a variety of factors, including digestive disorders, food intolerances, and stress. Treatment for colic in these populations may involve addressing the underlying cause, as well as medications to relieve symptoms such as pain and nausea.
Intraoperative complications refer to any unexpected events or problems that occur during a surgical procedure. These complications can range from minor issues, such as bleeding or infection, to more serious problems, such as organ damage or death. Intraoperative complications can be caused by a variety of factors, including surgical errors, anesthesia errors, or underlying medical conditions of the patient. It is important for surgeons and other medical professionals to be aware of the potential for intraoperative complications and to take steps to prevent them whenever possible. If a complication does occur, it is important to address it promptly and appropriately to minimize the risk of further harm to the patient.
Ursodeoxycholic acid (UDCA) is a bile acid that is naturally produced by the liver. It is used in the medical field to treat a variety of liver and gallbladder conditions, including primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH). UDCA works by reducing inflammation and improving the function of the liver and bile ducts. It is usually taken by mouth in the form of capsules or tablets.
Chronic pancreatitis is a long-term inflammatory condition of the pancreas that causes damage to the gland over time. It is characterized by persistent inflammation and scarring of the pancreas, which can lead to the destruction of pancreatic tissue and the development of complications such as diabetes, malnutrition, and pain. Chronic pancreatitis can be caused by a variety of factors, including chronic alcohol abuse, smoking, genetic mutations, and certain infections or autoimmune diseases. The symptoms of chronic pancreatitis can vary widely and may include abdominal pain, weight loss, nausea and vomiting, and changes in bowel movements. Diagnosis of chronic pancreatitis typically involves a combination of medical history, physical examination, blood tests, imaging studies such as ultrasound or CT scans, and sometimes endoscopic retrograde cholangiopancreatography (ERCP) or biopsy. Treatment of chronic pancreatitis depends on the underlying cause and the severity of the disease. It may include lifestyle changes such as quitting smoking and limiting alcohol consumption, medications to manage pain and other symptoms, and in severe cases, surgery to remove damaged tissue or create a bypass to allow digestive enzymes to flow around the damaged pancreas.
Anastomosis, Roux-en-Y is a surgical procedure used to create a connection between two different parts of the gastrointestinal tract. It is commonly used in the treatment of conditions such as obesity, type 2 diabetes, and gastroesophageal reflux disease (GERD). In a Roux-en-Y anastomosis, a small section of the stomach is removed and the remaining stomach is connected to a section of the small intestine that has been bypassed. The bypassed section of the small intestine is then connected to the remaining stomach, forming a "Y" shape. This allows food to bypass a large portion of the small intestine, which can help to reduce the absorption of calories and improve blood sugar control. Roux-en-Y anastomosis is typically performed as part of a gastric bypass surgery, which involves creating a small pouch out of the stomach and attaching it directly to the small intestine. The bypassed section of the small intestine is then connected to the remaining stomach, forming the "Y" shape. This procedure is often used as a treatment for obesity and type 2 diabetes because it can help to significantly reduce a person's weight and improve their blood sugar control.
A diverticulum is a small pouch or sac that bulges out from the wall of a hollow organ, such as the colon, esophagus, or stomach. Diverticula are usually small and asymptomatic, but in some cases, they can become inflamed or infected, leading to diverticulitis. Diverticulosis, which is the presence of one or more diverticula, is a common condition, particularly in older adults. Diverticulitis is a more serious condition that requires medical treatment, including antibiotics and sometimes surgery.
Adenoma, Villous is a type of non-cancerous growth (benign tumor) that occurs in the lining of the colon or rectum. It is characterized by the presence of villi, which are finger-like projections that line the inner surface of the lining of the colon or rectum. These villi are covered in cells that produce mucus and other substances that help to protect the lining of the colon or rectum. Villous adenomas are usually small and may not cause any symptoms. However, in some cases, they can grow larger and cause problems such as bleeding, blockage of the colon or rectum, or the development of cancer. They are typically diagnosed through colonoscopy, a procedure in which a flexible tube with a camera on the end is inserted into the colon or rectum to examine the lining. Treatment for villous adenomas may include the removal of the growth through a procedure called polypectomy, in which the growth is removed using a snare or other tool. In some cases, if the growth is large or has certain characteristics, surgery may be necessary to remove the affected area of the colon or rectum. It is important to note that while villous adenomas are usually non-cancerous, they can sometimes develop into cancer, so it is important to have them monitored and treated if necessary.
Cholecystography is a medical imaging technique used to visualize the gallbladder and bile ducts. It involves the injection of a contrast material, usually iodinated contrast dye, into the bile ducts through a catheter inserted into the duodenum. The contrast material then fills the bile ducts and allows them to be seen on an X-ray or other imaging scan. Cholecystography is often used to diagnose conditions such as gallstones, bile duct blockages, and inflammation of the gallbladder (cholecystitis). It can also be used to guide the placement of a stent in the bile ducts or to help plan for surgery to remove the gallbladder (cholecystectomy). The procedure is typically performed on an outpatient basis and is relatively painless. However, some patients may experience mild discomfort or nausea after the procedure. The risks of cholecystography include allergic reactions to the contrast material and the potential for injury to the bile ducts or surrounding organs during the procedure.
Bile canaliculi are small channels that are present in the liver and are responsible for transporting bile from the liver cells (hepatocytes) to the bile ducts. Bile is a greenish-yellow fluid that is produced by the liver and is essential for the digestion and absorption of fats in the small intestine. The bile canaliculi are formed by the endoplasmic reticulum of the hepatocytes and are lined with a specialized membrane called the canalicular membrane. The bile canaliculi merge to form larger bile ducts, which eventually join to form the common bile duct. The common bile duct carries bile from the liver and gallbladder to the small intestine. Any damage or obstruction to the bile canaliculi can lead to a buildup of bile in the liver, which can cause a condition called cholestasis. This can result in symptoms such as jaundice (yellowing of the skin and eyes), itching, and abdominal pain.
Anastomosis, surgical refers to the surgical repair or creation of an anastomosis, which is a connection or between two blood vessels, ducts, or other tubular structures. This procedure is typically performed to restore blood flow or to bypass a blocked or damaged vessel or duct. The surgical anastomosis may be performed using various techniques, including hand-sewn sutures, stapling devices, or laser welding. The success of the anastomosis depends on several factors, including the quality of the tissue, the size and location of the vessels or ducts being connected, and the skill of the surgeon performing the procedure.
Cholagogues and choleretics are substances that stimulate the production and flow of bile in the liver and gallbladder. Bile is a greenish-yellow fluid that helps to digest fats and fat-soluble vitamins in the small intestine. Cholagogues and choleretics are often used to treat digestive disorders such as gallstones, jaundice, and fatty liver disease. They can also be used to increase bile flow in people who are taking certain medications that can reduce bile production. Some examples of cholagogues and choleretics include milk thistle, dandelion root, and artichoke leaf extract.
Postcholecystectomy Syndrome (PCS) is a group of symptoms that can occur after a person has had their gallbladder removed, also known as a cholecystectomy. These symptoms can include abdominal pain, nausea, vomiting, bloating, and diarrhea. PCS is not a common complication of cholecystectomy, but it can occur in up to 10% of people who have had the procedure. The exact cause of PCS is not fully understood, but it is thought to be related to changes in the digestive system after the removal of the gallbladder. Treatment for PCS typically involves managing the symptoms with medications and dietary changes. In some cases, additional procedures may be necessary to address the underlying cause of the symptoms.
Adenocarcinoma, papillary is a type of cancer that begins in the cells that line certain organs or glands in the body. It is a type of adenocarcinoma, which is a type of cancer that begins in glandular cells. Papillary adenocarcinoma is characterized by the growth of small, finger-like projections called papillae, which can be seen under a microscope. This type of cancer is most commonly found in the thyroid gland, but it can also occur in other organs such as the lungs, breast, and pancreas. Treatment for papillary adenocarcinoma typically involves surgery to remove the affected tissue, followed by radiation therapy or chemotherapy to kill any remaining cancer cells.
Fascioliasis is a parasitic infection caused by the liver fluke, Fasciola hepatica. The infection occurs when the fluke larvae, which are released into the environment by infected snails, are ingested by humans or animals. The flukes then migrate to the liver and bile ducts, where they can cause damage and inflammation. Symptoms of fascioliasis can include abdominal pain, fever, nausea, vomiting, diarrhea, and jaundice. In severe cases, the infection can lead to liver failure, cirrhosis, and even death. Fascioliasis is most common in rural areas where there is access to contaminated water or food sources. It is also found in some parts of Asia, Africa, South America, and Europe. Treatment typically involves the use of antiparasitic drugs to kill the flukes and alleviate symptoms. Prevention measures include avoiding contaminated water and food sources, and proper sanitation practices.
Liver diseases refer to a wide range of medical conditions that affect the liver, which is a vital organ responsible for many essential functions in the body. These diseases can be caused by various factors, including viral infections, alcohol abuse, drug toxicity, autoimmune disorders, genetic mutations, and metabolic disorders. Some common liver diseases include: 1. Hepatitis: An inflammation of the liver caused by a viral infection, such as hepatitis A, B, or C. 2. Cirrhosis: A chronic liver disease characterized by the scarring and hardening of liver tissue, which can lead to liver failure. 3. Non-alcoholic fatty liver disease (NAFLD): A condition in which excess fat accumulates in the liver, often as a result of obesity, insulin resistance, or a high-fat diet. 4. Alcoholic liver disease (ALD): A group of liver diseases caused by excessive alcohol consumption, including fatty liver, alcoholic hepatitis, and cirrhosis. 5. Primary biliary cholangitis (PBC): A chronic autoimmune liver disease that affects the bile ducts in the liver. 6. Primary sclerosing cholangitis (PSC): A chronic autoimmune liver disease that affects the bile ducts in the liver and can lead to cirrhosis. 7. Wilson's disease: A genetic disorder that causes copper to accumulate in the liver and other organs, leading to liver damage and other health problems. 8. Hemochromatosis: A genetic disorder that causes the body to absorb too much iron, leading to iron overload in the liver and other organs. Treatment for liver diseases depends on the underlying cause and severity of the condition. In some cases, lifestyle changes such as diet and exercise may be sufficient to manage the disease. In more severe cases, medications, surgery, or liver transplantation may be necessary.
Common bile duct
List of MeSH codes (C06)
Common bile duct stone
Biliary colic
CBD
Cholangitis (disambiguation)
Cholangiocarcinoma
Gallstone
Ernie Fletcher
Obeticholic acid
Pancreatic duct
Foregut
Cirrhosis
Liver function tests
Acute pancreatitis
Gallbladder disease
Bile duct
Nucleoporin
Kayser-Fleischer ring
Crohn's disease
Primary biliary cholangitis
Choledochoduodenostomy
Primary sclerosing cholangitis
Jaundice
Jean-François Calot
Cholecystectomy
Cholestasis
Bernhard Moritz Carl Ludwig Riedel
Choledochal cysts
Human body
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Overview
Intrahepatic7
- Even when the catheter is advanced to the proximal common hepatic duct, contrast dye preferentially fills the cystic duct and gallbladder rather than allowing visualization of the intrahepatic ductal system. (medscape.com)
- Intrahepatic cholangiocarcinoma (ICC) is a cancer of the bile ducts that accounts for around 10%-15% of all primary hepatic malignancies. (bmj.com)
- Production of ALP is increased during cholestasis, which is a decrease in bile flow due to intrahepatic or extrahepatic causes. (medmastery.com)
- Caroli disease and Caroli syndrome are rare congenital disorders of the intrahepatic bile ducts. (medscape.com)
- The term Caroli disease is applied if the disease is limited to ectasia or segmental dilatation of the larger intrahepatic ducts. (medscape.com)
- Multiple dilated intrahepatic bile ducts are present. (medscape.com)
- In Caroli disease, abnormalities of the bile duct occur at the level of the large intrahepatic ducts (ie, left and right hepatic ducts, segmental ducts), resulting in dilatation and ectasia. (medscape.com)
Pancreas6
- Magnetic resonance cholangiopancreatography or MRCP uses a powerful magnetic field, radio waves and a computer to evaluate the liver, gallbladder, bile ducts, pancreas and pancreatic duct for disease. (radiologyinfo.org)
- Magnetic resonance cholangiopancreatography (MRCP) is a special type of magnetic resonance imaging (MRI) exam that produces detailed images of the hepatobiliary and pancreatic systems, including the liver, gallbladder, bile ducts, pancreas and pancreatic duct . (radiologyinfo.org)
- These complex cases include tumors of the liver, bile ducts, pancreas and gastrointestinal tract. (baptist-health.com)
- When there's diffuse disease, all of the insulin-secreting cells in the pancreas are abnormal, but when it's focal disease, a very small cluster of cells measuring perhaps less than one-quarter of an inch in diameter are abnormal. (chop.edu)
- Gamma-glutamyl transpeptidase is elevated in the liver, biliary tract, and pancreas diseases as well as common bile duct obstruction. (medmastery.com)
- Elevated gamma-glutamyl transpeptidase (GGT) may indicate a disease of the liver, biliary tract, pancreas, or a common bile duct obstruction. (medmastery.com)
Hepatic ducts1
- The biliary tree also includes the cystic duct, the right and left hepatic ducts, and the common hepatic and common bile ducts, as well as a series of microscopic biliary vessels. (cdc.gov)
Gallstones5
- Gallstone disease refers to the condition where gallstones are either in the gallbladder or common bile duct. (rajhomeopathy.in)
- Gallstones are more common among women than men and occur more commonly after the age of 40. (rajhomeopathy.in)
- The most common causes are gallstones and excessive alcohol consumption. (sterlinghospitals.com)
- The most common types include gallstones and biliary atresia. (sterlinghospitals.com)
- Helicobacter DNA was detected in the gallbladder tissue and bile of 28% and 18% respectively of the patients, but was not detected in any of the gallstones. (who.int)
Pancreatic duct3
- [ 24 ] In these patients, a small distal CBD entered the pancreatic duct at 2-3.5 cm from the ampulla of Vater, whereas the normal common channel is 5 mm or less. (medscape.com)
- The pressure in the pancreatic duct (30-50 cm H 2 O) exceeds the pressure in the CBD (25-30 cm H 2 O), favoring reflux of pancreatic secretions into the CBD. (medscape.com)
- ERCP is an invasive procedure that evaluates the bile ducts and/or the pancreatic duct. (radiologyinfo.org)
Centers for Diseas3
- Centers for Disease Control and Prevention. (cdc.gov)
- The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the US Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
Extrahepatic1
- and 10) cancer of the gallbladder and extrahepatic ducts. (cdc.gov)
Fibrosis9
- Cystic fibrosis is a chronic, progressive, and usually fatal inherited disease, though most patients with the condition live into at least their 30s. (fortherecordmag.com)
- The signs and symptoms of cystic fibrosis vary depending on the severity of the disease. (fortherecordmag.com)
- Respiratory infections are very common in patients with cystic fibrosis since bacteria that would normally be removed with the clearing of mucus are trapped. (fortherecordmag.com)
- This form is less common than Caroli syndrome, in which malformations of small bile ducts and congenital hepatic fibrosis are also present. (medscape.com)
- [ 1 ] As with congenital hepatic fibrosis , Caroli syndrome is often associated with autosomal recessive polycystic kidney disease (ARPKD) . (medscape.com)
- therefore, Caroli syndrome is thought to belong in the same spectrum of disease as congenital hepatic fibrosis and ARPKD. (medscape.com)
- Caroli syndrome (ectasia of the large and small bile ducts with congenital hepatic fibrosis) is more common than Caroli disease (ectasia of only the large bile ducts). (medscape.com)
- Patients with Caroli syndrome or Caroli disease may have cholangitis and may also have complications of portal hypertension as is observed in congenital hepatic fibrosis. (medscape.com)
- Nakanuma Y, Harada K, Sato Y, Ikeda H. Recent progress in the etiopathogenesis of pediatric biliary disease, particularly Caroli's disease with congenital hepatic fibrosis and biliary atresia. (medscape.com)
Inflammatory bowel d2
- This is a symptom that can be caused by a variety of conditions, including haemorrhoids, inflammatory bowel disease, colon cancer, or infection. (sterlinghospitals.com)
- To each sample, new approaches to the management of creatitis, inflammatory bowel disease, 200 µL of AL buffer were added and various gastroduodenal disorders [1]. (who.int)
Cystic duct2
- In this patient with persistent elevation of liver-associated enzymes, the contrast entering the biliary ductal system preferentially enters the cystic duct. (medscape.com)
- It consists of a rounded fundus, smooth body and tapering neck, which becomes contiguous with the cystic duct and attaches to the porta hepatis. (cdc.gov)
Symptoms14
- Due to the location of the gallbladder and the fact that many people don't have symptoms in the early stages of the disease, gallbladder cancer is often hard to find. (integrisok.com)
- Diagnosing gallbladder cancer starts with your healthcare provider asking you questions about your health history, symptoms, risk factors and family history of disease. (integrisok.com)
- A diverse spectrum of diseases affects the biliary system, often presenting with similar clinical signs and symptoms. (medscape.com)
- Common digestive symptoms include foul-smelling greasy stools, pale or clay-colored stools, poor weight gain/growth, meconium ileus, severe constipation, increased gas or bloating or a swollen belly, nausea, and loss of appetite. (fortherecordmag.com)
- Early symptoms of the disease include tiredness and itching. (europa.eu)
- Symptoms of Caroli disease or syndrome are more common in female patients than in male patients. (medscape.com)
- What symptoms might liver disease cause? (gastrohb.com)
- Liver disease symptoms aren't always obvious in the beginning. (gastrohb.com)
- This is a common condition that affects the large intestine, causing symptoms such as abdominal pain, bloating, and changes in bowel habits. (sterlinghospitals.com)
- The most common types are hepatitis A, B, and C. Symptoms may include fatigue, jaundice, and abdominal pain. (sterlinghospitals.com)
- Other individuals have a multitude of the most severe symptoms of end-stage liver disease and a limited chance for survival. (medscape.com)
- Common signs and symptoms may stem from decreased hepatic synthetic function (eg, coagulopathy), portal hypertension (eg, variceal bleeding), or decreased detoxification capabilities of the liver (eg, hepatic encephalopathy). (medscape.com)
- Specific medical therapies may be applied to many liver diseases in an effort to diminish symptoms and to prevent or forestall the development of cirrhosis. (medscape.com)
- Symptoms of autosomal dominant polycystic kidney disease are usually not present until adulthood. (msdmanuals.com)
Abnormalities2
- Biliary disease is caused by abnormalities in bile composition, biliary anatomy, or function. (medscape.com)
- You can inherit gene abnormalities that lead to liver disease. (gastrohb.com)
Incidence3
- Caroli disease and Caroli syndrome are very rare, with an estimated incidence of less than 1 case per 100,000 population. (medscape.com)
- The ITFDE defined eradication as 'reduction of the worldwide incidence of a disease to zero as a result of deliberate efforts, obviating the necessity for further control measures. (cdc.gov)
- Between the extremes of disease 'control' (reduction in incidence and/or prevalence) and 'eradication,' several intermediate levels of impact on diseases may be described. (cdc.gov)
Obstruction1
- Biliary-type pain, the typical clinical presentation, is due to obstruction of the bile duct lumen. (medscape.com)
Cholelithiasis2
Affects2
- Fascioliasis is a zoonotic disease caused by the foodborne trematode F. hepatica or F. gigantica , which has a complex life cycle and mainly affects sheep and cattle ( 2 ). (cdc.gov)
- This is a condition that affects the bile ducts, which are tubes that carry bile from the liver to the small intestine. (sterlinghospitals.com)
Cholesterol5
- Cholesterol, ordinarily insoluble in water, comes into solution by forming vesicles with phospholipids (principally lecithin) or mixed micelles with bile salts and phospholipids. (medscape.com)
- When the ratio of cholesterol, phospholipids, and bile salts is outside an optimum range, cholesterol monohydrate crystals may come out of solution from multilamellar vesicles. (medscape.com)
- Cholesterol supersaturation of bile appears to be a prerequisite for gallstone formation, which involves a variety of factors that affect the activity of low-density lipoprotein (LDL) uptake, hepatic 3-methylglutaryl coenzyme A reductase (HMG CoA), acyl cholesterol-lecithin acyltransferase, and 7-alpha hydroxylase. (medscape.com)
- This type of liver disease is often accompanied by excess body weight, high cholesterol, and Type 2 diabetes. (gastrohb.com)
- Secreted by the liver, bile is composed largely of bile salts, bile pigments and small amounts of organic materials such as cholesterol, lecithin, fatty acid and mucin. (cdc.gov)
Salts1
- Bile salts are produced by the liver and are essential for the digestion and absorption of fat in the small intestine. (cdc.gov)
MRCP1
- Your doctor may use MRCP image only the bile ducts. (integrisok.com)
Tubes1
- This test can't be used to get biopsy samples or to place small tubes (stents) in the ducts to keep them open. (integrisok.com)
Cancers3
- Other forms include bile duct cancer and cancers that start in your liver blood vessels. (gastrohb.com)
- The percentage of all cancers combined and then categorized into the 10 most cases diagnosed among females ranged from 47.1% to 68.2% common cancer types among all Asian and NHPI persons. (cdc.gov)
- These increased risks were not limited to cancers only but were also observed for neurologic diseases, cardiovascular diseases, and diseases of the urinary system. (cdc.gov)
Stasis1
- Finally, gallbladder hypomotility and bile stasis appear to promote gallstone formation and growth, which may be important in diabetes, pregnancy, oral contraceptive use in women, and prolonged fasting in critically ill patients on total parenteral nutrition. (medscape.com)
Cirrhosis6
- The most common reason for a transplant in adults is cirrhosis . (medlineplus.gov)
- salt free diet is the best way to go for liver disease, especially those of us with incurable cirrhosis. (liversupport.com)
- Because of the damage to the ducts, bile acids, essential components of bile, build up in the liver causing damage to liver tissue and leading to liver cirrhosis (scarring of the liver). (europa.eu)
- Primary biliary cholangitis is a long-term debilitating and life-threatening disease because it can lead to liver cirrhosis and liver failure, and may increase the risk of liver cancer. (europa.eu)
- 10-15 % of these patients can have a progressive course disease that ends in a nonfunctioning liver we refer to as having cirrhosis. (gastrohb.com)
- Its liver cirrhosis, underlying malignancy the samples were centrifuged at 8000 relevance to human disease, specifically or familial hypercholesterolaemia were rpm for 10 min. (who.int)
Digestive6
- The Department plays a primary role in diagnosing and treating digestive system diseases. (z2hospital.com)
- The Department of Gastroenterology and Hepatology at Sterling Hospitals Ahmedabad is a specialized unit that provides comprehensive care for patients with digestive and liver diseases. (sterlinghospitals.com)
- Ultrasonography of the gallbladder is included as part of the digestive diseases component of the NHANES III. (cdc.gov)
- In addition to ultrasonography, the digestive diseases component will also obtain information from interviews with sample persons. (cdc.gov)
- Digestive diseases represent the third largest economic burden of illness in the United States. (cdc.gov)
- Gallbladder disease is the most costly digestive illness, generating more than a billion dollars per year in direct costs for medical care. (cdc.gov)
Acute2
- Of the circulatory diseases, the highest ASMRs for goods, difficulties of access to health services, and spiral- men were due to acute myocardial infarction and cere- ing poverty, which negatively affect living conditions and brovascular disease. (cdc.gov)
- Millions of Americans suffer from either acute or chronic liver disease. (gastrohb.com)
Primary4
- Primary biliary cholangitis is a disease in which there is long-term damage to the small bile ducts in the liver. (europa.eu)
- By activating PPARs, this medicine is expected to reduce the levels of bile acid, thereby reducing damage of liver tissue that occurs in primary biliary cholangitis. (europa.eu)
- Information from the NHANES III studies should yield a better understanding of the prevalence and risk factors of gallbladder disease, and lead to the development of improved primary prevention measures. (cdc.gov)
- 7. Primary cancer of the Bile ducts. (cdc.gov)
Gastrointestinal1
- proposed that H. pylori All patients received diagnostic upper to the QIAamp spin column in a 2 present in human bile samples might rep- gastrointestinal endoscopy and gastric mL collection tube were processed ac- resent a risk factor for gallstone formation biopsies were taken to confirm the cording to Qiagen protocol. (who.int)
Fats3
- Bile is produced by the liver and is channeled by the biliary ductal system into the intestinal tract for the emulsification and absorption of fats. (medscape.com)
- These ducts transport fluid called bile from the liver to the intestines, where it helps to digest fats. (europa.eu)
- The liver performs vital roles, including detoxifying your blood, recirculating red blood cell breakdown products, metabolizing medications and digested food, producing bile to assist with dissolving fats for absorption, and helps to maintain blood glucose levels. (gastrohb.com)
Occur1
- Liver cancer can also occur if the disease spreads from another part of your body (secondary liver cancer or metastatic cancer). (gastrohb.com)
Autosomal dominan2
- A rare association with autosomal dominant polycystic kidney disease (ADPKD) has also been reported. (medscape.com)
- Autosomal Dominant Polycystic Kidney Disease (ADPKD) Polycystic kidney disease (PKD) is a hereditary disorder of renal cyst formation causing gradual enlargement of both kidneys, sometimes with progression to renal failure. (msdmanuals.com)
Cohort2
Peptic ulcer d1
- The supernatant was to peptic ulcer disease, gastritis and gastric excluded from the study. (who.int)
Lecithin1
- Arachidonyl lecithin, which is absorbed from the alimentary tract and secreted into the bile, stimulates prostanoid synthesis by gallbladder mucosa and promotes mucus hypersecretion, while inhibitors of prostaglandin inhibit mucus secretion. (medscape.com)
Diabetes3
- Fenofibrate was not shown to reduce coronary heart disease morbidity and mortality in a large, randomized controlled trial of patients with type 2 diabetes mellitus. (nih.gov)
- diovascular disease, hypertension, diabetes mel itus, and A total of 27,065 deaths were reported for 1999 through cancer. (cdc.gov)
- Among women, the highest ASMRs tion has endured intense conflict characterized by severe were due to circulatory disease, cancer, and diabetes mel- restrictions on the movement of Palestinian people and litus. (cdc.gov)
Cholecystectomy4
- Background: The feasibility of elective single-incision laparoscopic (SILS) cholecystectomy for biliary colic and dyskinesia has been well-established in the literature, but limited data has been published concerning the approach for more severe disease. (sages.org)
- Conclusion: SILS cholecystectomy for complicated gallbladder disease appears to be a safe and feasible option when compared to SILS cholecystectomy performed electively. (sages.org)
- Further prospective analyses comparing SILS cholecystectomy to traditional multiport laparoscopy in both complicated and uncomplicated disease are required. (sages.org)
- DNA was extracted from gallbladder, bile and gallstone samples from 50 patients undergoing cholecystectomy. (who.int)
Rectum1
- Among the 25 subgroups, the most common cancer breast, colon and rectum, lung and bronchus, and cervix uteri) type varied. (cdc.gov)
Liver failure1
- Liver disease can lead to liver failure, so it's important to diagnose and treat liver disease as early as possible. (gastrohb.com)
Diagnose2
- They can help diagnose liver and bile duct diseases. (integrisok.com)
- Our surgeons work closely with endocrinologists, specialists in the field of hormone-related diseases, to diagnose and treat hormone health issues and the complications that can arise from them. (baptist-health.com)
Gallbladder disease1
- A retrospective chart review was conducted to assess the safety and feasibility of the SILS approach in the setting of complicated gallbladder disease. (sages.org)
Alcoholic fatty liver d5
- There are 2 main types of fatty liver disease: non-alcoholic fatty liver disease & alcoholic fatty liver disease. (rajhomeopathy.in)
- 2012. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. (medmastery.com)
- Alcoholic fatty liver disease results from excessive alcohol use. (gastrohb.com)
- For some types of liver disease, for example, both nonalcoholic and alcoholic fatty liver disease, lifestyle changes like losing weight and discontinuing alcohol use, is the first-line treatment. (gastrohb.com)
- This is a long-term condition that can be caused by a variety of factors, including viral hepatitis, alcohol consumption, and non-alcoholic fatty liver disease. (sterlinghospitals.com)
Malformation1
- Caroli syndrome belongs to a subcategory of diseases thought to originate from DP malformation. (medscape.com)
Small2
- These tests can also be used to get samples of cells or fluid to look for cancer, or to place a stent (small tube) inside a duct to keep it open. (integrisok.com)
- The ducts are reached by passing an endoscope down the throat and into the small intestine. (integrisok.com)
Diagnosis5
- Our care team at Baptist Health Surgical Clinic of Central Arkansas provides complete evaluation, diagnosis and surgical offerings for a wide variety of conditions and diseases. (baptist-health.com)
- We have established clinical standards for the diagnosis and treatment of these diseases as a result of our extensive experience accumulated over many years' practice. (z2hospital.com)
- For expert diagnosis and treatment of liver disease, call Jay P. Diliberto, MD Inc. or schedule an appointment online now. (gastrohb.com)
- Diagnosis of autosomal recessive polycystic kidney disease may be difficult, especially without a family history. (msdmanuals.com)
- For example, although breast cancer was the most were further categorized by stage at diagnosis as early-stage, common in 18 subgroups, lung cancer was the most common late-stage, or unknown. (cdc.gov)
Syndrome4
- Hence, "freedom from the Ancestor Syndrome" (Ancelin Schutzenberger) is the prime objective of the "therapy", which aims to release the descendant from the genetic programming, so that he, in turn, is spared from inflicting diseases upon future generations. (learninggnm.com)
- type II, or complex Caroli disease, is also known as Caroli's syndrome. (medscape.com)
- Patients with Caroli disease or Caroli syndrome may have recurrent episodes of cholangitis and are also at risk for associated bacteremia and sepsis. (medscape.com)
- Both Caroli disease and Caroli syndrome are associated with a risk of cholangiocarcinoma at a rate of 100 times that of the general population. (medscape.com)
GENETIC DISEASES1
- Chronic liver diseases include genetic diseases such as Hemochromatosis, alcoholic liver disease, Hepatitis C, Hepatitis B, and Fatty Liver as well as Fatty Liver at its worst, referred to as NASH. (gastrohb.com)
Fatty liver disease3
- Fatty liver disease also called as hepatic steatosis, is a condition where excess fat builds up in the liver. (rajhomeopathy.in)
- A person suffering from fatty liver disease may experience tiredness or pain in the upper right side of the abdomen. (rajhomeopathy.in)
- Nonalcoholic fatty liver disease occurs when too much fat accumulates in your liver cells. (gastrohb.com)
Tissue1
- ABSTRACT Earlier reports on the detection of Helicobacter DNA in the gallbladder tissue of patients with biliary diseases have shown discordant results. (who.int)
Evaluate2
- The purpose of the ITFDE was to establish criteria and apply them systematically to evaluate the potential eradicability of other diseases in the aftermath of the Smallpox Eradication Program. (cdc.gov)
- This issue of MMWR Recommendations and Reports consolidates the deliberations of the International Task Force for Disease Eradication (ITFDE), which was convened six times from 1989 through 1992 to evaluate diseases as potential candidates for global eradication (1-7). (cdc.gov)
Ultrasound1
- IgG titers remained positive (320, by enzyme immunoassay), and flukes could be visualized by ultrasound in the gallbladder and common bile duct ( Figure ). (cdc.gov)
Form1
- Hepatocellular carcinoma is the most common form of liver cancer. (gastrohb.com)
Renal failure1
- renal failure is common in childhood. (msdmanuals.com)
Caroli3
- Hepatic ultrasonogram of a neonate with Caroli disease. (medscape.com)
- [ 1 ] . Because reports have described cases limited to the left lobe of the liver, some have described Caroli disease as either localized or diffuse. (medscape.com)
- Caroli disease, bilateral diffuse cystic renal dysplasia, situs inversus, postaxial polydactyly, and preauricular fistulas: a ciliopathy caused by a homozygous NPHP3 mutation. (medscape.com)
Cancer2
- Based on this new model, Epigeneticists are of the view that diseases such as cancer are not caused by defective genes, as claimed by mainstream geneticists, but rather by non-genetic factors that alter the expression of genes without changing the DNA sequence. (learninggnm.com)
- In 2001, the West Bank had a population of approxi- were due to diseases of the circulatory system, cancer, and mately 2.1 mil ion (6). (cdc.gov)