Commiphora
Medicine, Ayurvedic
Resins, Plant
Pregnenediones
A safe, effective, herbal antischistosomal therapy derived from myrrh. (1/27)
Schistosomiasis is a widespread helminthic disease. Treatment of schistosomiasis is based on chemotherapy with praziquantel, which is the drug of choice. Since resistance to praziquantel has been demonstrated, alternative drugs must be considered. Myrrh is an oleo-gum resin from the stem of the plant Commiphora molmol. This study was carried out on 204 patients with schistosomiasis. The drug was given at a dose of 10 mg/kg of body weight/day for three days, and induced a cure rate of 91.7%. Re-treatment of cases who did not respond with a dose of 10 mg/kg of body weight/day for six days gave a cure rate of 76.5%, increasing the overall cure rate to 98.09%. The drug was well tolerated, and side effects were mild and transient. Twenty cases provided biopsy specimens six months after treatment and none of them showed living ova. (+info)Further bisabolenes and dammarane triterpenes of Commiphora kua resin. (2/27)
From the resins of Commiphora kua a novel bisabolene; 6-hydroxy-2-methyl-5-(5'-hydroxy-1'(R),5'-dimethylhex-3'-enyl)-phenol together with two new dammarane triterpenes, 3beta,16beta,20(S),25-tetrahydroxydammar-23-ene and 3beta-acetoxy-16beta,20(S),25-trihydroxydammar-23-ene, have been isolated. In addition, being reported are known compounds identified as 2-methyl-5-(4'(S)-hydroxy-1'(R),5'-dimethylhex-5'-enyl)-phenol, 2-acetoxyfuranodienone, 2-methoxyfuranodienone, 3beta,16beta,20(R)-trihydroxydammar-24-ene and its acetate derivative, 3beta-acetoxy-16beta,20(R)-dihydroxydammar-24-ene, and beta-amyrin and its acetate derivative. 2-Methyl-5-(4'(S)-hydroxy-1'(R),5'-dimethylhex-5'-enyl)-phenol displayed fungicidal activity against Cladosporium cucumernum on TLC assay. (+info)Dammarane triterpenes of Commiphora confusa resin. (3/27)
Fractionation of a steam distilled residue of Commiphora confusa resin has yielded four novel dammarane triterpenes characterised as (20S)-3beta-acetoxy-12beta,16beta-trihydroxydammar-24-ene, (20S)-12beta,16beta-trihydroxydammar-24-ene-3beta-O-beta-glucopyranoside, (20S)-3beta-acetoxy-12beta,16beta,25-tetrahydroxydammar-23-ene, and (20S)-3beta,12beta,16beta,25-pentahydroxydammar-23-ene. The known compounds beta-amyrin, 3beta-amyrinacetate, 2-methoxyfuranodienone, 2-acetoxyfuranodienone, (20R)-3beta-acetoxy-16beta-dihydroxydammar-24-ene, (20R)-3beta,16beta-trihydroxydammar-24-ene, 3beta-acetoxy-16beta-hydroxydammar-24-ene, 3beta-hydroxydammar-24-ene, 3beta-acetoxydammar-24-ene, and beta-sistosterol were also isolated from the same extract. The structures of the compounds were determined using spectroscopic, physical, and chemical methods. (+info)Absolute stereostructures of polypodane-type triterpenes, myrrhanol A and myrrhanone A, from guggul-gum resin (the resin of Balsamodendron mukul). (4/27)
Two new polypodane-type triterpenes, myrrhanol A and myrrhanone A, were isolated from the 50% aqueous methanolic extract of guggul-gum resin [the resin of Balsamodendron (=Commiphora) mukul HOOK]. The structures of the new constituents, including their absolute configurations, were determined on the basis of chemical and physicochemical evidence. (+info)Myrrh--Commiphora chemistry. (5/27)
Myrrh and opopanax has been used throughout history in incense and as a perfume. Since Bible times it has been used for the treatment of wounds. The first attempts to identify content compounds were almost 100 years ago. In this review we discuss the present state of knowledge in the chemistry of substances of Commiphora spp. (+info)Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak. (6/27)
The present study was undertaken to gain insights into the molecular mechanism of cell death (apoptosis) by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, using PC-3 human prostate cancer cells as a model. The viability of PC-3 cells, but not a normal prostate epithelial cell line (PrEC), was reduced significantly on treatment with guggulsterone in a concentration-dependent manner. Guggulsterone-mediated suppression of PC-3 cell proliferation was not due to perturbation in cell cycle progression but caused by apoptosis induction characterized by appearance of subdiploid cells and cytoplasmic histone-associated DNA fragmentation. Guggulsterone-induced apoptosis was associated with induction of multidomain proapoptotic Bcl-2 family members Bax and Bak. Interestingly, the expression of antiapoptotic proteins Bcl-2 and Bcl-xL was initially increased in guggulsterone-treated PC-3 cells but declined markedly following a 16- to 24-hour treatment with guggulsterone. Ectopic expression of Bcl-2 in PC-3 cells failed to confer significant protection against guggulsterone-induced cell death. On the other hand, SV40 immortalized mouse embryonic fibroblasts derived from Bax-Bak double knockout mice were significantly more resistant to guggulsterone-induced cell killing compared with wild-type cells. Guggulsterone treatment resulted in cleavage (activation) of caspase-9, caspase-8, and caspase-3, and guggulsterone-induced cell death was significantly attenuated in the presence of general caspase inhibitor as well as specific inhibitors of caspase-9 and caspase-8. In conclusion, the present study indicates that caspase-dependent apoptosis by guggulsterone is mediated in part by Bax and Bak. (+info)Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni. (7/27)
This work has been carried out to investigate the effect of Schistosoma mansoni infection on mice livers after treatment with the ethanolic extract of Citrus reticulata root or the oleo-resin extract from Myrrh of Commiphora molmol tree (Mirazid), as a new antishistosomal drug. Marker enzymes for different cell organelles were measured; succinate dehydrogenase (SDH); lactate dehydrogenase (LDH) and its isoenzymes; glucose-6-phosphatase (G-6-Pase); acid phosphatase (AP) and 5'- nucleotidase. Liver function enzymes; aspartate aminotransferase (AST); alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were also estimated. Parasitological studies through ova count and worm burden will also be taken into consideration. The results showed a marked reduction in SDH, LDH, AST, and ALT enzyme activities and a significant increase in G-6-Pase, AP, 5'- nucleotidase, and ALP after S. mansoni infection. A noticeable alteration in LDH subunits were also noticed. Treatment with C. reticulata or Mirazid improved all the previous enzyme activities with a noticeable reduction in ova count and worm burden. (+info)Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation. (8/27)
Bone resorption is commonly associated with aging and with certain types of cancer, including multiple myeloma and breast cancer. What induces bone resorption is not fully understood, but the role of osteoclasts is well established. Recently, receptor activator of nuclear factor-kappaB (NF-kappaB) ligand (RANKL), a member of the tumor necrosis factor superfamily, was implicated as a major mediator of bone resorption, suggesting that agents that can suppress RANKL signaling have the potential to inhibit bone resorption or osteoclastogenesis. Guggulsterone [4,17(20)-pregnadiene-3,16-dione], isolated from the guggul tree Commiphora mukul and used to treat osteoarthritis and bone fractures, was recently shown to antagonize the farnesoid X receptor, decrease the expression of bile acid-activated genes, and suppress the NF-kappaB activation induced by various carcinogens. We investigated whether guggulsterone could modulate RANKL signaling and osteoclastogenesis induced by RANKL or tumor cells. We found that treatment of monocytes with guggulsterone suppressed RANKL-activated NF-kappaB activation (as indicated by gel-shift assay) and that this suppression correlated with inhibition of IkappaBalpha kinase and phosphorylation and degradation of IkappaBalpha, an inhibitor of NF-kappaB. Guggulsterone also suppressed the differentiation of monocytes to osteoclasts in a dose-dependent and time-dependent manner. Suppression of osteoclastogenesis by the NF-kappaB-specific inhibitory peptide implies a link between NF-kappaB and osteoclastogenesis. Finally, differentiation to osteoclasts induced by coincubating human breast tumor cells (MDA-MB-468) or human multiple myeloma (U266) cells with monocytes was also completely suppressed by guggulsterone. Collectively, our results indicate that guggulsterone suppresses RANKL and tumor cell-induced osteoclastogenesis by suppressing the activation of NF-kappaB. (+info)Commiphora is a genus of plants in the Burseraceae family, commonly known as the frankincense tree. The resin produced by these trees has been used for centuries for medicinal and aromatic purposes. In the medical field, Commiphora resin is sometimes used topically to treat skin conditions such as acne, eczema, and psoriasis. It may also have anti-inflammatory and analgesic properties, and has been studied for its potential use in treating cancer and other diseases. However, more research is needed to fully understand the therapeutic potential of Commiphora resin.
In the medical field, "Resins, Plant" typically refers to a group of natural substances that are extracted from plants and have a variety of medicinal properties. These resins are often used in traditional medicine to treat a range of conditions, including pain, inflammation, and infection. Some examples of plant resins that are commonly used in medicine include: 1. Frankincense: A resin that is extracted from the Boswellia tree and has been used for centuries to treat a variety of conditions, including arthritis, digestive issues, and respiratory problems. 2. Myrrh: A resin that is extracted from the Commiphora tree and has been used for centuries to treat a variety of conditions, including gum disease, digestive issues, and respiratory problems. 3. Copaiba: A resin that is extracted from the Copaifera tree and has been used for centuries to treat a variety of conditions, including pain, inflammation, and infection. 4. Pistacia: A resin that is extracted from the Pistacia tree and has been used for centuries to treat a variety of conditions, including respiratory problems, digestive issues, and skin conditions. Plant resins are often used in combination with other herbs and natural substances to create traditional remedies and herbal supplements. However, it is important to note that the use of plant resins in medicine should always be done under the guidance of a qualified healthcare professional.
Pregnenediones are a group of steroid hormones that are synthesized from cholesterol in the adrenal cortex. They include cortisol, corticosterone, and aldosterone, which are important for regulating various physiological processes in the body, such as metabolism, blood pressure, and the immune response. These hormones are also involved in the stress response and play a role in the development and function of the reproductive system.
Plant extracts refer to the active compounds or bioactive molecules that are extracted from plants and used in the medical field for various therapeutic purposes. These extracts are obtained through various extraction methods, such as solvent extraction, steam distillation, and cold pressing, and can be used in the form of powders, liquids, or capsules. Plant extracts have been used for centuries in traditional medicine and are now widely used in modern medicine as well. They are used to treat a wide range of conditions, including inflammation, pain, anxiety, depression, and cancer. Some examples of plant extracts used in medicine include aspirin (extracted from willow bark), quinine (extracted from cinchona bark), and morphine (extracted from opium poppy). Plant extracts are also used in the development of new drugs and therapies. Researchers extract compounds from plants and test them for their potential therapeutic effects. If a compound shows promise, it can be further developed into a drug that can be used to treat a specific condition. It is important to note that while plant extracts can be effective in treating certain conditions, they can also have side effects and may interact with other medications. Therefore, it is important to consult with a healthcare professional before using plant extracts as a form of treatment.
Commiphora
Commiphora angolensis
Commiphora wightii
Commiphora aprevalii
Commiphora schimperi
Commiphora kataf
Commiphora africana
Commiphora madagascariensis
Commiphora gileadensis
Commiphora socotrana
Commiphora guidottii
Commiphora saxicola
Commiphora kua
Commiphora caudata
Commiphora myrrha
Somali Acacia-Commiphora bushlands and thickets
Northern Acacia-Commiphora bushlands and thickets
Southern Acacia-Commiphora bushlands and thickets
Alphonse Révillon d'Apreval
Curzerene
Balm of Gilead
List of Ngorongoro Crater plants
Opopanax (perfumery)
List of plants of Burkina Faso
List of trifoliate plants
Myrrha
Spathionema
Burseraceae
Onycha
Amyris
Commiphora - Wikipedia
Commiphora madagascarensis - Rare Plant Research
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Mukul19
- Silverline Chemicals have become a respectable entity to get Commiphora Mukul In Kansas . (silverlinechemicals.com)
- Being one of the reputable Commiphora Mukul Manufacturers In Kansas , we follow ethical manufacturing practices. (silverlinechemicals.com)
- Our manufacturing unit is equipped with excellent manufacturing resources that help us process and pack Commiphora Mukul following hygienic practices. (silverlinechemicals.com)
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- Our offered Commiphora Mukul is widely used in various industries. (silverlinechemicals.com)
- Our Commiphora Mukul is further packed conventionally using modern technology. (silverlinechemicals.com)
- Which Company Commiphora Mukul Should I Buy? (silverlinechemicals.com)
- Silverline Chemicals is one of the prominent Commiphora Mukul Manufacturers in India that extract Commiphora Mukul from different parts of the plant, including leaves, bark, flowers, twigs, and fruits, by the process of steam/hydro distillation. (silverlinechemicals.com)
- How Can Your Commiphora Mukul Help Me? (silverlinechemicals.com)
- Here is the list of various health benefits of Commiphora Mukul that makes it the choice of all. (silverlinechemicals.com)
- What Is The Best Way To Store The Commiphora Mukul? (silverlinechemicals.com)
- To maintain the Commiphora Mukul properly, here are the various steps that help you to keep it safe. (silverlinechemicals.com)
- The Commiphora Mukul is harmful if you don't use it properly. (silverlinechemicals.com)
- Never use photosensitizing Commiphora Mukul before UV exposure. (silverlinechemicals.com)
- Do I Need To Dilute Commiphora Mukul When Using Them Topically? (silverlinechemicals.com)
- It is necessary to dilute the Commiphora Mukul while using it. (silverlinechemicals.com)
- If you use Undiluted Commiphora Mukul , it will cause harm to your skin and also cause severe irritation or sensitization. (silverlinechemicals.com)
- Gum guggul extracts (GGEs) are botanical preparations derived from the oleoresin of the Commiphora mukul tree. (nih.gov)
- Guggulu resin (Commiphora mukul) is a penetrating herb that scrapes out naturally accumulating toxins from the body channels. (ayurvedicherbsdirect.com)
Myrrha11
- Commiphora myrrha Essential Oil starts with our directly sourced oleo gum resin which is then hydro-distilled in small batches for a truly artisanal result. (boswellness.com)
- Commiphora myrrha Resin is our directly sourced oleo gum resin harvested from the plains and hills of Eastern Africa. (boswellness.com)
- Commiphora Myrrha Resin is directly sourced from the tree to you with no additives or alterations. (boswellness.com)
- 1. Cytotoxic sesquiterpenoid dimers from the resin of Commiphora myrrha Engl. (nih.gov)
- 6. Sesquiterpenoids from the resinous exudates of Commiphora myrrha and their neuroprotective effects. (nih.gov)
- 7. New compounds from Commiphora myrrha (Nees) Engl. (nih.gov)
- 11. Isolation and biological activities of neomyrrhaol and other terpenes from the resin of Commiphora myrrha. (nih.gov)
- 12. Four new sesquiterpenes from Commiphora myrrha and their neuroprotective effects. (nih.gov)
- 16. Hepatoprotective effect of Commiphora myrrha against d-GalN/LPS-induced hepatic injury in a rat model through attenuation of pro inflammatory cytokines and related genes. (nih.gov)
- 20. Bioactive sesquiterpenoids and steroids from the resinous exudates of Commiphora myrrha. (nih.gov)
- The essential oil (Commiphora myrrha or Commiphora molmol) is red, sticky and thick, and has a smoky earthy scent. (untrainedhousewife.com)
Resin4
- Serving Size:One Teaspoon (4.9 mL) Active Ingredients: Gum Myrrh (Commiphora molmol) Resin Extract (1:1) 4.9mL Other Ingredients:Grain alcohol (30%) and purified water. (eslimmers.com)
- Botanical Name: Commiphora molmol Resin 1:1 Vegetarian Formula Gluten Free Hypoallergenic Recommended Dosage:Not intended for use during pregnancy. (eslimmers.com)
- Botanical Name: Commiphora molmol Resin 1:1 Vegetarian Formula Gluten Free. (eslimmers.com)
- The oleo-gum resin of Commiphora wightii has been utilized for centuries in Ayurvedic medicine for the treatment of various diseases. (phcog.com)
Wightii1
- Commiphora wightii (Indian Bedellium, Guggulu) reduces cholesterol and triglyceride levels. (mygenericpharmacy.com)
Molmol2
- Professional Formulas - Myrrh (Commiphora molmol) - 16 FL. (eslimmers.com)
- More Items Related To Professional Formulas Myrrh Commiphora molmol 16 FL OZ 473 mL. (eslimmers.com)
Engl17
- Commiphora alaticaulis J.B.Gillett & Vollesen Commiphora anacardiifolia Dinter & Engl. (wikipedia.org)
- A.Weeks & Gostel Commiphora angolensis Engl. (wikipedia.org)
- Commiphora antunesii Engl. (wikipedia.org)
- Commiphora aprevalii Guillaumin, endemic to Madagascar Commiphora arafy H.Perrier Commiphora arenaria Thulin Commiphora baluensis Engl. (wikipedia.org)
- Commiphora boranensis Vollesen Commiphora brevicalyx H.Perrier Commiphora buruxa Swanepoel Commiphora caerulea Burtt Commiphora campestris Engl. (wikipedia.org)
- Commiphora cervifolia Van der Walt Commiphora chaetocarpa J.B.Gillett Commiphora chevalieri Engl. (wikipedia.org)
- Commiphora chiovendana J.B.Gillett ex Thulin Commiphora ciliata Vollesen Commiphora coleopsis H.Perrier Commiphora confusa Vollesen Commiphora corrugata J.B.Gillett & Vollesen Commiphora crenatoserrata Engl. (wikipedia.org)
- Commiphora dinteri Engl. (wikipedia.org)
- Commiphora discolor Mendes Commiphora drake-brockmanii Sprague Commiphora dulcis Engl. (wikipedia.org)
- Commiphora edulis (Klotzsch) Engl. (wikipedia.org)
- Commiphora erlangeriana Engl. (wikipedia.org)
- Commiphora fulvotomentosa Engl. (wikipedia.org)
- Commiphora glandulosa Schinz Commiphora glaucescens Engl. (wikipedia.org)
- Commiphora gracilifrondosa Dinter ex Van der Walt Commiphora grandifolia Engl. (wikipedia.org)
- Commiphora grosswelleri Engl. (wikipedia.org)
- Commiphora guerichiania Engl. (wikipedia.org)
- Commiphora guillauminii H.Perrier Commiphora gurreh Engl. (wikipedia.org)
Kataf1
- Commiphora kataf (Forssk. (homolaicus.com)
Gileadensis3
- Commiphora gardoensis J.B.Gillett ex Thulin Commiphora gariepensis Swanepoel Commiphora giessii Van der Walt Commiphora gileadensis (L.) C.Chr. (wikipedia.org)
- Gary partnered with a small farm east of Jerusalem to grow Balm of Gilead (Commiphora Gileadensis) trees. (dgaryyoung.com)
- By 2013, 3,500 new Commiphora Gileadensis trees had been propagated, along with more than 100 frankincense trees. (dgaryyoung.com)
Acacia-Commiphora1
- vegetation consists primarily of Acacia-Commiphora bushes. (cdc.gov)
Burseraceae1
- The genus of the myrrhs, Commiphora, is the most species-rich genus of flowering plants in the frankincense and myrrh family, Burseraceae. (wikipedia.org)
Opobalsamum2
- Commiphora opobalsamum), producing balsam of Mecca. (wikipedia.org)
- 9. Cycloartane-type triterpenoids and sesquiterpenoids from the resinous exudates of Commiphora opobalsamum. (nih.gov)
Bursera1
- The closely related sister genus to Commiphora, Bursera, has been used as a model genus to study patterns of evolution in the New World seasonally dry tropical forests. (wikipedia.org)
Resins1
- Products from many species of Commiphora have been used for various purposes, sometimes as timber, building material, and natural fencing, but more often valued for the aromatic resins produced by several members of the genus. (wikipedia.org)
ABIES1
- El nombre común de bálsamo de Gilead se refiere más frecuentemente a POPULUS y en ocasiones a ABIES. (bvsalud.org)
Leaves1
- Leaves in Commiphora are pinnately compound (or very rarely unifoliolate). (wikipedia.org)
Plant1
- Commiphora can serve as a model genus for understanding plant evolution in the drier regions of the Old World tropics, particularly in eastern continental Africa and Madagascar, where diversity in the genus is concentrated. (wikipedia.org)