The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
An alkylating agent of value against both hematologic malignancies and solid tumors.
An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)
The use of IONIZING RADIATION to treat malignant NEOPLASMS and some benign conditions.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
The total amount of radiation absorbed by tissues as a result of radiotherapy.
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
Tumors or cancer of the LUNG.
Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
A malignant epithelial tumor with a glandular organization.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Adenoviral gene transfer into the normal and injured spinal cord: enhanced transgene stability by combined administration of temperature-sensitive virus and transient immune blockade. (1/14907)

This study characterized gene transfer into both normal and injured adult rat dorsal spinal cord using first (E1-/E3-) or second (E1-/E2A125/E3-, temperature-sensitive; ts) generation of replication-defective adenoviral (Ad) vectors. A novel immunosuppressive regimen aimed at blocking CD4/CD45 lymphocytic receptors was tested for improving transgene persistence. In addition, the effect of gene transfer on nociception was also evaluated. Seven days after treatment, numerous LacZ-positive cells were observed after transfection with either viral vector. By 21 days after transfection, beta-galactosidase staining was reduced and suggestive of ongoing cytopathology in both Ad-treated groups, despite the fact that the immunogenicity of LacZ/Adts appeared less when compared with that elicited by the LacZ/Ad vector. In contrast, immunosuppressed animals showed a significant (P < or = 0.05) increase in the number of LacZ-positive cells not displaying cytopathology. In these animals, a concomitant reduction in numbers of macrophages/microglia and CD4 and CD8 lymphocytes was observed. Only animals that received LacZ/Adts and immunosuppression showed transgene expression after 60 days. Similar results were observed in animals in which the L4-L5 dorsal roots were lesioned before transfection. Gene transfer into the dorsal spinal cord did not affect nociception, independent of the adenovirus vector. These results indicate that immune blockade of the CD4/CD45 lymphocytic receptors enhanced transgene stability in adult animals with normal or injured spinal cords and that persistent transgene expression in the spinal cord does not interfere with normal neural function.  (+info)

Systemic administration of rIL-12 synergistically enhances the therapeutic effect of a TNF gene-transduced cancer vaccine. (2/14907)

Interleukin-12 (IL-12) is a potent antitumor cytokine, which induces and enhances the activity of natural killer (NK) cells, lymphokine activated killer (LAK) cells and cytotoxic T lymphocytes (CTL). IL-12 also stimulates IFN-gamma production from both T cells and NK cells. In this study, we transfected methylcholanthrene-induced fibrosarcoma (MCA-D) with TNF gene and investigated the therapeutic effect of TNF gene-transduced cancer vaccine and whether the vaccination effect is enhanced by systemic administration of recombinant IL-12 (rIL-12), in a murine model. TNF gene-transduced cancer vaccine or systemic administration of rIL-12 showed slight or moderate inhibition of pre-established tumor. However, simultaneous application of the vaccine and rIL-12 resulted in complete eradication. The cytotoxicity of CTL against parental tumor cells was enhanced with the combination of the vaccine and rIL-12, and IFN-gamma production from spleen cells also increased synergistically. Our findings show that synergistic enhancement of CTL activity and IFN-gamma production could play an important role in the antitumor effect of combination therapy using TNF gene-transduced cancer vaccine and rIL-12.  (+info)

Reirradiation combined with hyperthermia in recurrent breast cancer results in a worthwhile local palliation. (3/14907)

Both experimental and clinical research have shown that hyperthermia (HT) gives valuable additional effects when applied in combination with radiotherapy (RT). The purpose of this study was evaluation of results in patients with recurrent breast cancer, treated at the Daniel den Hoed Cancer Center (DHCC) with reirradiation (re-RT; eight fractions of 4 Gy twice weekly) combined with HT. All 134 patients for whom such treatment was planned were included in the analysis. The complete response rate in 119 patients with macroscopic tumour was 71%. Including the 15 patients with microscopic disease, the local control rate was 73%. The median duration of local control was 32 months, and toxicity was acceptable. The complete response (CR) rate was higher, and the toxicity was less with the later developed 433-MHz HT technique compared with the 2450-MHz technique used initially. With this relatively well-tolerated treatment, palliation by local tumour control of a worthwhile duration is achieved in the majority of patients. The technique used for hyperthermia appeared to influence the achieved results. The value of HT in addition to this re-RT schedule has been confirmed by a prospective randomized trial in a similar patient group. In The Netherlands, this combined treatment is offered as standard to patients with breast cancer recurring in previously irradiated areas.  (+info)

A prospective randomized study of megestrol acetate and ibuprofen in gastrointestinal cancer patients with weight loss. (4/14907)

The use of megestrol acetate in the treatment of weight loss in gastrointestinal cancer patients has been disappointing. The aim of the present study was to compare the combination of megestrol acetate and placebo with megestrol acetate and ibuprofen in the treatment of weight loss in such patients. At baseline, 4-6 weeks and 12 weeks, patients underwent measurements of anthropometry, concentrations of albumin and C-reactive protein and assessment of appetite, performance status and quality of life using EuroQol-EQ-5D and EORTC QLQ-C30. Thirty-eight and 35 patients (median weight loss 18%) were randomized to megestrol acetate/placebo or megestrol acetate/ibuprofen, respectively, for 12 weeks. Forty-six (63%) of patients failed to complete the 12-week assessment. Of those evaluable at 12 weeks, there was a decrease in weight (median 2.8 kg) in the megestrol acetate/placebo group compared with an increase (median 2.3 kg) in the megestrol acetate/ibuprofen group (P<0.001). There was also an improvement in the EuroQol-EQ-5D quality of life scores of the latter group (P<0.05). The combination of megestrol acetate/ibuprofen appeared to reverse weight loss and appeared to improve quality of life in patients with advanced gastrointestinal cancer. Further trials of this novel regimen in weight-losing patients with hormone-insensitive cancers are warranted.  (+info)

The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cell recipients. (5/14907)

We analysed 57 patients with non-myeloid malignancies who received a non-purged autologous PBSCT. All had similar mobilisation and conditioning regimens. A high prior chemotherapy score and the number of chemotherapy lines used (P = 0.015 and P = 0.01, respectively) were adverse predictors of CD34 cell yields. Lower CD34 values (P = 0.002) were seen in patients treated with potent stem cell toxins (BCNU, melphalan, CCNU and mustine), designated toxicity factor 4 agents (TF4). All patients infused with grafts containing CD34 cell doses between 1.0 and 2.0 x 10(6)/kg (range 1.25-1.90) engrafted by day 51. The only variable associated with slow platelet recovery was exposure to TF4 (P = 0.007). The majority of patients with CD34 >1.0 x 10(6)/kg achieved rapid and sustained engraftment and the only predictive factor of delayed recovery is prior exposure to stem cell toxins. Potential PBSCT candidates should if possible avoid first line and salvage chemotherapy containing TF4 drugs. We therefore advocate a minimum CD34 threshold of >1.0 x 10(6)/kg in patients without extensive prior chemoradiotherapy, and > or = 2.0 x 10(6)/kg in all other patients.  (+info)

Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. (6/14907)

The effect of an extensive prophylactic antimicrobial regimen was prospectively assessed in 126 patients after high-dose chemotherapy and autologous PBSC. They received ciprofloxacin (500 mg/12 h), acyclovir (200 mg/6 h), and itraconazole (200 mg/12 h) orally until neutrophil recovery. Febrile patients received i.v. imipenem (500 mg/6 h) to which vancomycin and amikacin were added if fever persisted for 2-3 and 5 days, respectively. Amphotericin B lipid complex was further given on day 7 or 8 of fever. Median times for a neutrophil count of >0.5 x 10(9)/l and a platelet count of >20 x 10(9)/l were 9 and 11 days. Severe neutropenia (<0.1 x 10(9)/l) lasted for a median of 5 days in which 72% of febrile episodes and 50% of cases of bacteremia occurred. Gram-positive bacteria were isolated in 30 of 40 episodes of bacteremia, 25 of which were caused by Staphylococcus epidermidis. Clinical foci were the intravascular catheter in 35 cases, respiratory infection in 11, cellulitis in two, anal abscess in one, and neutropenic enterocolitis in one. The high incidence of febrile episodes (94%) and bacteremias (31%) may be due to the lack of efficacy of antimicrobial prophylaxis and the persistence of a 5-day period of severe neutropenia.  (+info)

Lymphomatoid granulomatosis following autologous stem cell transplantation. (7/14907)

Lymphomatoid granulomatosis (LYG) is a rare angio-destructive lymphoproliferative disorder (LPD) of uncertain etiology, with prominent pulmonary involvement. Recent studies indicate that LYG is an Epstein-Barr virus (EBV)-associated B cell LPD with large numbers of background reactive T lymphocytes (T cell-rich B cell lymphoma). Although the disease frequently, but not exclusively, occurs in various immunodeficiency states, it has not been reported in association with the transient immunosuppression following autologous bone marrow/peripheral stem cell transplantation (ABM/PSCT). We describe a patient who developed lymphomatoid granulomatosis of the lung approximately 2 weeks after high-dose chemotherapy and autologous peripheral stem cell transplantation for multiple myeloma. Although molecular studies showed no evidence of EBV genome in the biopsy material, the serologic profile with high IgM titers was suggestive of primary EBV infection. Complete radiologic remission occurred following reconstitution of the patient's immune response after a 2-week course of ganciclovir treatment. Despite the apparently low frequency of LPD (both LYG and EBV-associated post-transplant lymphoma) in the ABMT setting, we believe that it should be considered in the differential diagnosis of patients whose clinical course following ABMT is complicated by fevers, in the absence of an identifiable infectious process.  (+info)

Phase I study of eniluracil, a dihydropyrimidine dehydrogenase inactivator, and oral 5-fluorouracil with radiation therapy in patients with recurrent or advanced head and neck cancer. (8/14907)

5-Fluorouracil (5-FU) is an effective enhancer of radiation therapy (RT) in head and neck cancers. Due to rapid, predominantly hepatic metabolism by dihydropyrimidine dehydrogenase (DPD) and suggested clinical benefit from prolonged drug exposure, 5-FU is commonly given by continuous infusion. Eniluracil is a novel DPD-inactivator designed to prolong the half-life of 5-FU and provide sustained plasma concentrations of 5-FU with oral dosing. We conducted a Phase I study of the safety and efficacy of eniluracil given with oral 5-FU in patients receiving concurrent RT for recurrent or advanced squamous cell carcinomas of the head and neck. Thirteen patients with recurrent, metastatic, or high-risk (defined as an expected 2-year survival rate of <10%) head and neck cancer were enrolled and treated with concomitant chemoradiotherapy on an every-other-week schedule. Eniluracil at a fixed dose [20 mg twice a day (BID)] was given for 7 consecutive days (days 1-7). 5-FU and RT were given on 5 consecutive days (days 2-6). One patient was treated with once-daily RT (2.0 Gy fractions). The remaining patients received hyperfractionated RT (1.5-Gy fractions BID). The initial dose of 5-FU was 2.5 mg/m2 given BID. Dose escalation in patient cohorts was scheduled at 2.5-mg/m2 increments, with intrapatient dose escalation permitted. Lymphocyte DPD activity and serum 5-FU and uracil concentrations were monitored during two cycles. DPD activity was completely or nearly completely inactivated in all patients. Sustained, presumed therapeutic concentrations of 5-FU were observed at a dose of 5.0 mg/m2 given BID. Cumulative dose-limiting myelosuppression (both neutropenia and thrombocytopenia) was observed during the fourth and fifth cycles following administration of 5.0 mg/m2 5-FU BID. One patient died of neutropenic sepsis during cycle 4. Other late cycle toxicities included diarrhea, fatigue, and mucositis. Grade 3 mucositis was observed in 4 patients, but no grade 4 mucositis or grade 3 or 4 dermatitis was observed. A second patient death occurred during cycle 1 of treatment. No specific cause of death was identified. The study was subsequently discontinued. Cumulative myelosupression was the significant dose-limiting toxicity of oral 5-FU given with the DPD-inactivator eniluracil on an every-other-week schedule. Clinical radiation sensitization was not observed, based on the absence of dose-limiting mucositis and dermatitis. Alternative dosing schedules need to be examined to determine the most appropriate use of eniluracil and 5-FU as radiation enhancers.  (+info)

Patients with locally advanced esophageal cancer who are treated with trimodality therapy have a high recurrence rate. Preclinical evidence suggests that inhibition of cyclooxygenase 2 (COX2) increases the effectiveness of chemoradiation, and observational studies in humans suggest that COX-2 inhibition may reduce esophageal cancer risk. This trial tested the safety and efficacy of combining a COX2 inhibitor, celecoxib, with neoadjuvant irinotecan/cisplatin chemoradiation. This single arm phase 2 trial combined irinotecan, cisplatin, and celecoxib with concurrent radiation therapy. Patients with stage IIA-IVA esophageal cancer received weekly cisplatin 30 mg/m2 plus irinotecan 65 mg/m2 on weeks 1, 2, 4, and 5 concurrently with 5040 cGy of radiation therapy. Celecoxib 400 mg was taken orally twice daily during chemoradiation, up to 1 week before surgery, and for 6 months following surgery. Forty patients were enrolled with stage IIa (30 %), stage IIb (20 %), stage III (22.5 %), and stage IVA (27.5 %)
The abscopal effect is mediated by a systemic anti-tumor immune response and reflects the regression of non-irradiated metastatic lesions at a distance from the primary site of irradiation. This review will focus on understanding the biological rationale behind the abscopal effect of radiotherapy (RT), which has a recently renewed interest as a result of the successes achieved with immunotherapy and RT in combination. Both RT and immunotherapy are standard components of modern treatment regimens. Combination of these two modalities results in an increased response in the irradiated lesions themselves and the metastatic regions distant from the site of irradiation. We will summarize the abscopal effect of radiotherapy, in particular, the synergistic effect of RT and immunotherapy.
Fingerprint Dive into the research topics of Long-term follow-up of the RTOG 9501/intergroup phase III trial: Postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck. Together they form a unique fingerprint. ...
Based on positive results from the Radiation Therapy Oncology Group (RTOG) 85-01 trial, the conventional nonsurgical treatment of esophageal carcinoma is combined-modality therapy. Dose intensification of the RTOG 85-01 regimen, examined in the Intergroup (INT)-0123/RTOG 94-05 trial, did not improve local control or survival. Areas of clinical investigation include the development of combined-modality therapy regimens with newer systemic agents, the use of 18F-fluorodeoxyglucose positron-emission tomography to assist in the development of innovative radiation treatment planning techniques, and the identification of prognostic molecular markers. The addition of surgery following primary combined-modality therapy apparently does not improve survival, but this finding is controversial.
The analysis was based on a total of 468 patients with a median age of 66 years; 64% were younger than age 70, 19% were aged 70 to 75, and 17% were older than age 75. Among all patients, 82% were male. Approximately 94% had transitional cell carcinoma; 61% had clinical stage T2 tumors, and 35% had clinical stage T3. Median follow-up was 4.3 years for all patients and 7.8 years among 205 survivors.. Seventy-two percent of patients had a complete response to combined-modality therapy. The 5- and 10-year estimated overall survival rates were 57% and 36%, respectively; 5- and 10-year estimated disease-specific survival rates were 71% and 65%.. The majority of local failures in the bladder were non-muscle invasive, with an estimated 5- and 10-year incidence of 31% and 36%. The 5- and 10-year estimates for muscle-invasive failure rates were 13% and 14%, and 5- and 10-year estimates of distant metastases were 31% and 35%.. This recurrence pattern underscores the need for careful post-treatment ...
In this study, we show in breast and colon carcinoma models that fractionated local radiotherapy to one palpable tumor can synergize with CTLA-4 blockade to induce antitumor T-cell immunity and inhibit a second palpable tumor outside the radiation field. This abscopal effect was not seen with radiotherapy alone. Although localized tumor irradiation by itself has been shown to enhance the generation of tumor-specific T cells in both preclinical models and patients, the therapeutic effects of this response remain undetermined (3, 19). Clearly, irradiation to the primary tumor was required in our models to induce growth inhibition of the secondary tumors outside the field because CTLA-4 blockade by itself was ineffective (Figs. 2 and 6). This is consistent with the hypothesis that radiation-induced immunogenic tumor cell death as well as its induction of danger signals contribute to generate an in situ vaccine (20-22). Whereas the response generated is not sufficient to be therapeutically ...
The addition of chemo-radiotherapy following surgery to remove pancreatic cancer tumours has been shown to reduce the risk of the cancer returning researchers in the USA have found.. The use of adjuvant radiotherapy has been a controversial topic over the years with many studies reporting conflicting evidence about whether or not the use of chemo- radiotherapy is beneficial.. The researchers from the Mayo Clinic in the USA, reporting in the International Journal of Radiation Oncology, Biology and Physics ((ASTRO)) studied 458 patients who had received pancreatic cancer surgery between March 1987 and January 2011. Out of those, 378 had received chemotherapy + chemo-radiotherapy after surgery and 80 had received only chemotherapy.. The chemotherapy in this study typically consisted of six cycles of gemcitabine and the chemo-radiotherapy consisted of 50.4Gy in 28 fractions concurrent with 5-fluorouracil. Of those who had received chemotherapy + chemo-radiotherapy following their surgery, 80 per ...
Results of radiation given to patients with AIDS-related high-grade CNS lymphoma have been disappointing, with short survival times due to infection complications. However, complete response has been documented after radiation in some patients. High-dose MTX will be used to improve the possibility of a greater antineoplastic response than that obtained by radiation alone. Since the underlying immunodeficiency state is not affected by therapy directed against the lymphoma, patients are still prone to life-threatening opportunistic infections or relapse of lymphomatous disease within the CNS. Accordingly, AZT will also be used in an attempt to alter the overall natural history of the disease.. Radiation begins on day 1 of therapy. Patients receive dexamethasone orally (PO) or by intravenous injection (IV) on days 1-10. MTX IV over 6 hours weekly for a total of 4 doses starts 1 week after completion of the cranial radiation. Leucovorin (LCV) IV or PO begins 6 hours after MTX has been completed over ...
Results of radiation given to patients with AIDS-related high-grade CNS lymphoma have been disappointing, with short survival times due to infection complications. However, complete response has been documented after radiation in some patients. High-dose MTX will be used to improve the possibility of a greater antineoplastic response than that obtained by radiation alone. Since the underlying immunodeficiency state is not affected by therapy directed against the lymphoma, patients are still prone to life-threatening opportunistic infections or relapse of lymphomatous disease within the CNS. Accordingly, AZT will also be used in an attempt to alter the overall natural history of the disease.. Radiation begins on day 1 of therapy. Patients receive dexamethasone orally (PO) or by intravenous injection (IV) on days 1-10. MTX IV over 6 hours weekly for a total of 4 doses starts 1 week after completion of the cranial radiation. Leucovorin (LCV) IV or PO begins 6 hours after MTX has been completed over ...
The abscopal effect can sometimes increase survival with cancer. Learn about what cancers and treatments may have this response, and why it occurs.
Generating and grading the abscopal effect: proposal for comprehensive evaluation of combination immunoradiotherapy in mouse models
Generating and grading the abscopal effect: proposal for comprehensive evaluation of combination immunoradiotherapy in mouse models
The standard of care for women with stage III/IVA endometrial cancer following surgery has been chemotherapy and radiation to prevent recurrence. But in a surprising new finding, radiation combined with chemotherapy did not ...
Two hundred and eighty-eight patients were treated for newly diagnosed colorectal or anal cancer at William Beaumont Hospital from 2008 to 2009. Within this population, forty patients were referred to the clinic preoperatively and forty-eight patients were referred postoperatively. Two hundred patients were never treated in the clinic at all during the study period. In terms of preoperative evaluation, clinic patients underwent significantly more NCCN-compliant testing than patients managed outside the clinic-abdomen CT (97.5% vs. 83.1%, p=0.03), chest CT (95% vs. 37.1%, p,0.0001), CEA testing (100% vs. 63.8%, p,0.0001), and TRUS for rectal cancer (88% vs. 37.7%, p,0.0001). In addition, a complete preoperative work-up was performed in the clinic group over three times more frequently for colon cases and over five times more frequently for rectal cancers when compared to the non-clinic group. Access to multimodal therapy was also significantly enhanced in patients referred to the clinic as ...
Combined-modality approaches for the treatment of non-small-cell lung cancer (NSCLC), head and neck cancer, and esophageal cancer offer survival benefits by improving locoregional control and treating micrometastatic disease. The taxanes are active, tolerable drugs in these solid tumors and have radiation-sensitizing activity. 1
Health,...Study confirms effectiveness of widely used approach experts say ...MONDAY Dec. 15 (HealthDay News) -- Men with locally advanced prostate...The addition of radiotherapy kept patients healthy much longer the Sw... The study will change practice in the treatment of locally advanced o...,Radiation,Plus,Hormone,Therapy,Cuts,Prostate,Cancer,Deaths,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
ABSTRACT: The multimodal therapy of ADHD with comorbidities proved its efficacy în comparison with the unimodal therapies. We will present the preliminary results of the first nine months of multimodal therapy, which has been applied on a number of 18 children and adolescents with ages between 8 and 17 years. ...
Truong MT, Zhang Q, Rosenthal DI, List M, Axelrod R, Sherman E, Weber R, Nguyen-Tân PF, El-Naggar A, Konski A, Galvin J, Schwartz D, Trotti A, Silverman C, Singh A, Godette K, Bonner JA, Jones CU, Garden AS, Shenouda G, Matthiesen C, Le QT, Bruner D: Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522. Int J Radiat Oncol Biol Phys 97(4): 687-699, March 2017 ...
More than 400 respected luminaries explore todays most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient.
As a first step toward developing quantitative models, investigators recently developed a mathematical framework to simulate the systemic dissemination of T cells activated in response to focal therapy.
Radiotherapy (RT), the major anti-cancer modality for more than half of cancer patients after diagnosis, has the advantage of local tumor control with relatively less systematic side effects comparing to chemotherapy. However, the efficacy of RT is limited by acquired tumor resistance leading to the risks of relapse and metastasis. To further enhance the efficacy of RT, with the renaissances of targeted immunotherapy (TIT), increasing interests are raised on RT combined with TIT including cancer vaccines, T-cell therapy, and antibody-based immune checkpoint blockers (ICB) such as anti-CTLA-4 and anti-PD1/PD-L1. In achieving a significant synergy between RT and TIT, the dynamics of radiation-induced response in tumor cells and stromal cells, especially the cross-talk between tumor cells and immune cells in the irradiated tumor microenvironment (ITME) as highlighted in recent literature are to be elucidated. The abscopal effect refereeing the RT-induced priming function outside of ITME could be ...
Primary Endpoint: To determine the maximum tolerated dose (MTD) of vorinostat + radiation therapy (RT) in patients with locally advanced pancreat
Improved dose tracking and a more multimodal approach are just a few of the ways treatment planning systems are delivering higher-quality radiation therapy
Recent results of a phase II/III in locally advanced Soft Tissue Sarcoma patients demonstrated clinical benefits of intratumorally injected HfO2-NP activated by radiotherapy compared to radiotherapy alone, validating their first-in-class mode of action. In addition, animal studies have reported that HfO2-NP+RT can induce an abscopal effect, where RT alone cannot. Here, using a mouse abscopal assay, we measured T cells infiltrates in treated and untreated tumors after HfO2-NP intratumor injection and activation with RT, and their role in the abscopal effect.. These data indicate that the immunogenic conversion of the tumor microenvironment triggered by HfO2-NP+RT generates the abscopal effect by activation of CD8+ T cells. HfO2-NP+RT may potentiate a pro-inflammatory microenvironment appropriate for enabling an anti-tumor immune response. It may act as effective in-situ cancer vaccine and be combined with immunotherapeutic agents across oncology.. ...
Loco-regional recurrences after intial surgery in patients with esophageal cancer remain a serious challenge to clinical oncologists. The NCCN Guidelines pointed out that a highly selected group of patients with local-regional tumor recurrence after initial surgery may be considered fit and able to tolerate concurrent radio-chemotherapy with a potential for cure [18]. In a line with the previous studies, our data indicated that salvage concurrent radio-chemotherapy was an active and promising treatment strategy for such patients, reaching a median OS of 13.3 months with tolerable side-effects.. The present protocol of concurrent radio-chemotherapy was completed in 74% (37/50) of the patients, and no serious treatment related toxicities were observed. The tumor response rate was nearly 72% in R-TP and R-FP group respectively, with a 3-year survival rate of 14%. These results are very similar to those reported in previous studies [13, 15]. Yamashita et al.[13] reported the results of radiotherapy ...
TY - JOUR. T1 - Adjuvant therapy in colorectal cancer. A randomized trial comparing radio-chemotherapy and radio-chemotherapy combined with methanol extraction residue of BCG, MER. AU - Robinson, E.. AU - Bartal, A.. AU - Cohen, Y.. AU - Milstein, D.. AU - Mekori, T.. PY - 1979/12/1. Y1 - 1979/12/1. N2 - Fifty-three patients with colorectal cancer (Dukes B 2 and C) were randomized after surgery. One group was treated by radio-and/or chemotherapy and the second by radio-and/or chemotherapy and MER. After 24 and 36 months a significant longer disease free interval, lower recurrence rate and better survival was found in the group treated by radio-chemo-and immunotherapy. Treatment was well tolerated and there were few local side effects from the MER injections. The long time efficacy of this adjuvant treatment whether it increases the cure rate or only delays recurrence requires longer follow-up.. AB - Fifty-three patients with colorectal cancer (Dukes B 2 and C) were randomized after surgery. ...
The aim of this retrospective study was to compare concurrent radiation therapy (RT) combined with peroral chemotherapy (UFT or TS-1) with conventional RT for T2N0 glottic cancer. Between 1974 and 2005, 153 patients with T2N0 glottic cancer were treated with radiation alone or radiation combined with peroral (UFT or TS-1) or intravenous chemotherapy. All except one patient were treated with 2 Gy per fraction, 5 fractions per week, totaling 60 Gy; and the remaining patient was treated with 1.8 Gy per fraction, 5 fractions per week, totaling 61.2 Gy. Eighty-three patients were concurrently given UFT, 24 were given TS-1, 23 intravenous chemotherapy (mainly cisplatin; the Pt Group), and 23 had no chemotherapy. The 5-year local control rate was 83.4%. Stratified by RT alone (the RT group) and concurrent chemoradiation therapy (the CCRT group), 5-year local control rates of the RT and CCRT groups were 82.7% and 83.4%, respectively (p=NS). Stratified by chemotherapy regimens of the CCRT group, 3-year ...
For all 250 patients, the overall median survival was 27 months, the cause-specific survival was 27 months, the local progression-free survival was 32 months, and distant metastasis-free survival was not achieved; and the respective 5-year survival rates were 27%, 32%, 45%, and 68%. CF achieved significantly inferior survival than either HFX RT alone or HFX RT-Pac/C (P = .0332 and P = .0013, respectively), and no difference was observed between the 2 HFX RT regimens (P = .1934). Only acute hematologic high-grade toxicity (grade ≥3) was more frequent with HFX RT-Pac/C than with either RT alone, whereas other toxicities were similar between the 3 treatment groups. ...
Rare Cancer News & Clinical Trials » Trial - Sarcoma » A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue ...
article{4430146, abstract = {Purpose: Combined-modality treatment is standard treatment for patients with clinical stage I/II Hodgkin lymphoma (HL). We hypothesized that an early positron emission tomography (PET) scan could be used to adapt treatment. Therefore, we started the randomized EORTC/LYSA/FIL Intergroup H10 trial evaluating whether involved-node radiotherapy (IN-RT) could be omitted without compromising progression-free survival in patients attaining a negative early PET scan after two cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) as compared with standard combined-modality treatment. Patients and Methods: Patients age 15 to 70 years with untreated clinical stage I/II HL were eligible. Here we report the clinical outcome of the preplanned interim futility analysis scheduled to occur after documentation of 34 events in the early PET-negative group. Because testing for futility in this noninferiority trial corresponds to testing the hypothesis of no difference, a ...
OncoLink, the Webs first cancer resource,provides comprehensive information on coping with cancer, cancer treatments, cancer research advances, continuing medical education, cancer prevention, and clinical trials
Results Out of the 12 patients in the study, 6 did not receive radiotherapy either because they elected for subsequent radical surgery (3 patients) or were unfit for further treatment and underwent close follow-up (3 patients).. In the radiotherapy group, 2 patients had pre-op Long-Course Chemo-radiotherapy (LCCRT) with a good partial response, 2 were included in the national TEM and Radiotherapy in Early Rectal cancer (TREC) trial and had pre-op Short Course radiotherapy (SCRT) and 2 had adjuvant LCCRT + Papillon contact radiotherapy following TEM.. Median follow-up was 20 months. Patients not undergoing radial surgery had 3 monthly MR and sigmoidoscopy for 1 year and 6 monthly MR and sigmoidoscopy for a further 2 years.. In the no-radiotherapy group, 1 of the 3 patients who underwent subsequent radical surgery had involved mesorectal lymph nodes and 1 of those undergoing close follow-up without radical surgery developed mesorectal nodal recurrence. In radiotherapy group 1 patient, in the TREC ...
Jonathan D. Schoenfeld, MD, MPhil, MPH, director, melanoma radiation oncology, physician, assistant professor of radiation oncology, Harvard Medical School, Dana-Farber Cancer Institute, discusses potential combination regimens of low-dose radiation therapy and immunotherapy to treat patients with head and neck cancer.
Selected high-risk patients with head and neck squamous cell carcinoma receive postoperative radiation therapy (RT), with or without concurrent chemotherapy, following primary surgical resection with the aim of improving locoregional control and surv
PubMed journal article [Combined-modality therapy for 150 cases of early-stage Hodgkins lymphoma were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
Positron emission tomography using fluoro-deoxy-glucose has demonstrated added value in the clinical management of patients with colorectal cancer [6]. This includes primary staging, detection of recurrence, prediction of individual prognosis, therapy response, and evaluation of treatment response as assessed in this investigation [8].. The interest in FDG-PET to assess tumour response to CRT began in the early 1990 s. Rectal cancer is a disease model of particular interest, not only for its high incidence, but also because an accurate and non-invasive method to evaluate response to preoperative CRT could lead to patients selection for minimally invasive surgical approaches or even selection of candidates for additional chemotherapy and observation without any kind of surgery [2, 3].. Experts at the Memorial Sloan-Kettering Cancer Center reported a pioneer prospective assessment of LARC response to preoperative CRT using FDG-PET in 2000 [9]. Today, literature is mixed in regard to the ability ...
Clinical trial for Gynecological Infections , GOG 0238: A Randomized Trial of Pelvic Irradiation with or without Concurrent Weekly Cisplatin in Patients with Pelvic-only Recurrence of Carcinoma of the Uterine Corpus.
A rarely seen phenomenon in cancer patients - in which focused radiation to the site of one tumor is associated with the disappearance of metastatic tumors all over the body - has been reported in a patient with melanoma treated with the immunotherapeutic agent ipilimumab (Yervoy™).
The survival of children with non-Hodgkins lymphoma (NHL) has improved in the recent past through the systematic application of intensive therapy employing involved field radiation plus combinations...
Prognosis of patients who present with metastasized rectal cancer is poor. Without treatment, median survival is estimated at six months. Treatment options are available for the primary tumor and the metastatic disease. The primary tumor may be resected or treated with radiation therapy. Resection of the primary tumor is controversial, as it may not improve the quality of life in patients with a poor prognosis due to the metastatic disease. As the majority of patients with primary stage IV rectal cancer present with a locally advanced primary tumor, resection of the primary tumor would necessitate preoperative radiation therapy. Metastatic disease may respond to chemotherapy. In recent years, advances in chemotherapy have increased the response rate to 40 percent. Some patients presenting with liver or lung metastases are candidates for resection of their metastatic disease. Neoadjuvant chemotherapy may increase the fraction of patients with resectable metastatic disease, or may allow for ...
OncoLink, the Webs first cancer resource,provides comprehensive information on coping with cancer, cancer treatments, cancer research advances, continuing medical education, cancer prevention, and clinical trials
Once-daily radiotherapy is not superior to twice-daily treatment for patients with small-cell lung cancer receiving concurrent chemoradiotherapy.
Delayed toxicity in the form of progressive damage after completion of treatment is a grave problem. Three patients (RadS6, RadS7, and RadS10) suffered grade 4 delayed toxicity, and all were predicted successfully (Table 1). Toxicity from extrinsic factors cannot be predicted by our approach. Of the five patients with radiation toxicity not predicted by NSC/HAT, at least two (RadS3 and RadS5) were at high risk for toxicity from unconventional treatment protocols. Patient RadS3 suffered grade 3 mucositis in an experimental trial that included high-dose radiation plus tirapazamine, cisplatin, and 5-fluorouracil. Review of patient data after closure of this trial revealed that 28 of 62 (45%) suffered mucositis of grade 3 or higher. Patient RadS5 had an arteriovenous malformation that was treated with stereotactic guidance of a single 18-Gy dose to a 1.8-cm3 volume in the midbrain and pons. After this patient was enrolled for study, Flickinger et al. (23) estimated that stereotactic radiotherapy to ...
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TY - JOUR. T1 - Potential Molecular Targets in the Setting of Chemoradiation for Esophageal Malignancies. AU - Jabbour, Salma K.. AU - Williams, Terence M.. AU - Sayan, Mutlay. AU - Miller, Eric D.. AU - Ajani, Jaffer A.. AU - Chang, Andrew C.. AU - Coleman, Norman. AU - El-Rifai, Wael. AU - Haddock, Michael. AU - Ilson, David. AU - Jamorabo, Daniel. AU - Kunos, Charles. AU - Lin, Steven. AU - Liu, Geoffrey. AU - Prasanna, Pataje G.. AU - Rustgi, Anil K.. AU - Wong, Rosemary. AU - Vikram, Bhadrasain. AU - Ahmed, Mansoor M.. N1 - Publisher Copyright: Published by Oxford University Press 2020.. PY - 2021/6/1. Y1 - 2021/6/1. N2 - Although the development of effective combined chemoradiation regimens for esophageal cancers has resulted in statistically significant survival benefits, the majority of patients treated with curative intent develop locoregional and/or distant relapse. Further improvements in disease control and survival will require the development of individualized therapy based on the ...
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-ener
This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors. Giving chemotherapy with radiation therapy may kill more tumor cells. This study may help doctors find out if lower-dose chemoradiation is as effective and has fewer side effects than standard-dose chemoradiation, which is the usual approach for treatment of this cancer type ...
This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors. Giving chemotherapy with radiation therapy may kill more tumor cells. This study may help doctors find out if lower-dose chemoradiation is as effective and has fewer side effects than standard-dose chemoradiation, which is the usual approach for treatment of this cancer type ...
In lieu of an abstract, here is a brief excerpt of the content: 136 CHAPTER 4 Radiation Therapy and Surgery Radiation therapy, like chemotherapy, is intended to selectively kill malignant cells while sparing normal cells as much as possible. Like chemotherapy, radiation therapy (also called radiotherapy) is most active against rapidly dividing populations of cells. Unlike most forms of chemotherapy, radiation can be applied locally, to specific areas of the body, rather than spreading throughout the entire body via the bloodstream. Radiation therapy may be used alone to treat people with localized lymphocytepredominant Hodgkin lymphoma or localized indolent NHL, but it is more commonly used in combination with chemotherapy (a form of combined modality treatment). Combined modality therapy is most frequently used to treat localized disease, generalized disease in which there is a specific bulky component, or an area of localized disease that remains after chemotherapy treatment. Combined modality ...
What changes are seen among patients with acromegaly after long-term multimodality therapy? Are these patients able to be biochemically controlled?
Cancer is a systemic (throughout the body) disease, no matter what your doctor tells you. Telling patients based on post-operation scans that we got it all is not the truth. Most cancers have been growing and spreading for 5 to 10 years before they are detected and diagnosed. Billions of cancer cells must be present to show up on any scan. Surgery can spread cancer. The word cure in oncology circles has up to fifty different definitions. The only real cure is the one where you live long enough to die from something other than cancer. These survivors are strong, and most utilize a protocol to treat cancer everywhere in their body, rather than relying solely on local surgery, local radiation, and/or chemotherapy. ~ Dr. Bruce West. ...
Diagnostic imaging is a sleuth: It can identify cancer, confirm clinical suspicions and define disease parameters, leading the way to optimum treatment. Wave...
Organ toxicity in cancer therapy is likely caused by an underlying disposition for given pathophysiological mechanisms in the individual patient. Mechanistic data on treatment toxicity at the patient level are scarce; hence, probabilistic and translational linkages among different layers of data information, all the way from cellular targets of the therapeutic exposure to tissues and ultimately the patients organ systems, are required. Throughout all of these layers, untoward treatment effects may be viewed as perturbations that propagate within a hierarchically structured network from one functional level to the next, at each level causing disturbances that reach a critical threshold, which ultimately are manifested as clinical adverse reactions. Advances in bioinformatics permit compilation of information across the various levels of data organization, presumably enabling integrated systems biology-based prediction of treatment safety. In view of the complexity of biological responses to cancer
2 or more types of treatment used alternately or together to get the best results. For example, surgery for cancer is often followed by chemotherapy to kill any cancer cells that may have spread from the original site. See also |b>adjuvant therapy|/b>,|b> neoadjuvant therapy, chemotherapy|/b>.
During high-dose chemotherapy, the patient receives high doses of chemotherapy, and possibly radiation therapy, in order to kill the cancer cells. Whi
Surgery and radiation are often used together in more advanced lesions. As combined treatment has evolved, surgery with postoperative radiation therapy is most often employed. Recent advances in reconstructive surgery have further improved functional and cosmetic outcomes.. In select instances, promising results are being obtained with combined chemotherapy and radiation therapy in an effort to avoid surgical resection.. ...
This unit (1) provides background into understanding how agents that target specific molecules or receptors (molecular‐targeted agents), in particular, agents affecting the tumor vasculature (perivasculature network in tumors), interact with and modify radiation therapy; (2) details factors affecting interpretation of results in murine tumor model experiments utilizing radiation therapy and drug combinations; and (3) provides specific protocols for the application of radiation therapy, both alone and in combination with chemotherapy and/or molecular‐targeted agents
The use of ADT for two months before and two months during RT for early PCa is associated with significantly increased overall survival.
Choose a membership level that meets your changing needs, knowing that each month you get to choose the therapy you want: either our True Transformation Facial or Holistic Wellness Massage that includes the choice of a single modality or multiple modalities customized to your individual needs and concerns.. ...
Dolore perineale worth texas. MEDICINA Archivi - Pagina 2 di 4 - Fisiosaan. Inoltre, verranno discussi nel dettaglio due disturbi pelvi-perineali, la cui minor -La sindrome del cingolo pelvico si caratterizza per un dolore pelvico Hence it would be worth considering them as an adjunct to conservative therapy. College of Science, The University of Texas at Arlington, Arlington, Texas ​ Dolore perineale e pelvico (sintomo per lo più tardivo). La presenza di un Tx: il tumore primitivo non può essere valutato. T0: non cè evidenza di the worth of preoperative multimodality therapy in patients with operable carcinoma of the.. risonanza magnetica multiparametrica della prostata a latina 2017.
We are thrilled to offer a wide range of the most advanced modalities that speed the healing process in conjunction with appropriate manual treatments
Combined Modality Therapy of Central Nervous System Tumors. ISBN 9783540006275. Hoh DJ, Liu CY, Pagnini PG, Yu C, Wang MY, ... Chained lightning: part III--Emerging technology, novel therapeutic strategies, and new energy modalities for radiosurgery. ... technology transfer and the implementation of advanced technologies to the therapy of brain diseases. In 1991, he was appointed ...
... the modalities can be combined; antibody-drug conjugates combine biologic and cytotoxic mechanisms into one targeted therapy. ... Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for ... the term biologic therapy is sometimes synonymous with targeted therapy when used in the context of cancer therapy (and thus ... Targeted therapy Targeted drug delivery Targeted molecular therapy for neuroblastoma Targeted therapy of lung cancer Treatment ...
"Intracranial choriocarcinoma causing precocious puberty and cured with combined modality therapy". Journal of Paediatrics and ...
"Manual Lymph Drainage Combined With Compression Therapy for Arm Lymph- edema Following Breast Cancer Treatment" (PDF). Swedish ... Stillerman, Elaine (2009). Modalities for Massage and Bodywork. Mosby. pp. 129-143. ISBN 032305255X. " ... Explanation of Manual lymphedema therapy on National Cancer Institute. (Articles with short description, Short description ... they returned to Copenhagen to teach other practitioners to use this therapy. Milady's Guide to Lymph Drainage Massage; Ramona ...
Mira, J.G.: Combined Modality Treatment for Small Cell Lung Cancer. Chapter in Combined Chemotherapy and Radiotherapy in ... He was elected Head of the Radiotherapy department of the Cancer Therapy & Research Center every year between 1993 and 2007. He ... He was named Director of Radiotherapy in the Cancer Therapy & Research Center, under the National Cancer Institute, where he ... McCracken, J.D. and Mira, J.G.: Concurrent Chemotherapy and Radiation Therapy for Limited Small Cell Lung Cancer. Monograph, ...
December 1983). "Intensive combined modality therapy including low-dose TBI in high-risk Ewing's Sarcoma Patients". Int. J. ... August 2003). "High-dose therapy for patients with primary multifocal and early relapsed Ewing's tumors: results of two ... total body irradiation has been explored as a treatment modality for high-risk Ewing sarcoma. However, subsequent findings ...
... will play a decisive role for ongoing intensified combined modality treatments for GI cancers. The following ... Particle therapy Charged particle therapy Hadron Microbeam Fast neutron therapy Boron neutron capture therapy Linear energy ... Proton Beam Therapy Proton therapy - MedlinePlus Medical Encyclopedia Proton Therapy What is Proton Therapy (Pages with non- ... Because scattering therapy was the first type of proton therapy available, most clinical data available on proton therapy- ...
Most commonly, an estrogen is combined with an antiandrogen to suppress and block testosterone. This allows for ... Estrogens are administered in various modalities including injection, transdermal patch, and oral tablets. The desired effects ... Transgender hormone therapy, also called hormone replacement therapy (HRT) or gender-affirming hormone therapy (GAHT), is a ... "Hormone therapy in transgender adults is safe with provider supervision; A review of hormone therapy sequelae for transgender ...
... is therefore often combined with other modalities such as in-person therapy. Important areas of ... Types of therapy available include motor training exercises, speech therapy, virtual reality, robotic therapy, goal setting, ... robotic therapy, community-therapy. Motor strengthening exercises are the most commonly implemented modality. In motor training ... Robotic therapy has even been combined with virtual reality telerehabilitation to create a virtual environment which responds ...
Haddock MG1, Miller RC, Nelson H. Combined modality therapy including intraoperative electron irradiation for locally recurrent ... Radiation Therapy Intraoperative Radiation Therapy (Proceedings of the Third International Symposium on Intraoperative) edited ... Abe M. History of Intraoperative radiation therapy. In:Debelbower RR, Abe M (eds) Intraoperative radiation therapy. CRC, Boca ... Frontiers of Radiation Therapy and Oncology vol 31. Editor(s): Vaeth, J.M. (Mill Valley, Calif.). New techniques in electron ...
The therapy normally lasts for 5 minutes and is repeated at least 4 times a day. Full treatment programs typically contain a ... The treatment modality of patterning was developed in the 1960s by Glenn Doman and Carl Delacato. The Institutes for the ... range of exercises combined with sensory stimulation, breathing exercises designed to increase oxygen flow to the brain, and ... and treatment primarily focuses on non-invasive physical therapy in each of these stages. In one such stage, the homolateral ...
It is possible that the two modalities have a synergistic effect and patients may benefit from combined treatment. Prior to the ... An animal tumor model demonstrated improved survival after combined treatment with RFA and radiation therapy compared to either ... Reduced tumor growth with combined radiofrequency ablation and radiation therapy in a rat breast tumor model. Radiology 2005. ... July 2006). "Percutaneous Image-guided Thermal Ablation and Radiation Therapy: Outcomes of Combined Treatment for 41 Patients ...
These therapy modalities are focused on empowering individuals to reduce stress levels and elicit a relaxation response in ... Holistic nursing combines standard nursing interventions with various modalities that are focused on treating the patient in ... Alternative therapies can include stress management, aroma therapy, and therapeutic touch. The combination of interventions ... Several of the therapies included in holistic nursing rely on therapeutic environments to be successful and effective. A ...
... hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the ... is a prostate cancer vaccine Newer forms of chemotherapy Gene therapy Photodynamic therapy Radiation therapy Reoviridae ( ... Reolysin drug therapy) Targeted therapy Natural killer cells can induce immunological memory. Research is being developed to ... Radiation therapy took hold in the 1900s. Chemotherapeutics were developed and refined throughout the 20th century. The U.S. ...
It is also used in feminizing hormone therapy for transgender women. PEP is a form of high-dose estrogen therapy. After an ... PEP has been compared to combined androgen blockade (CAB; castration plus flutamide) for the treatment of prostate cancer in a ... At 18.5 months, there was no difference in survival or cardiovascular toxicity between the two treatment modalities. These ... Oral estrogen therapy is as effective as orchiectomy in terms of cancer inhibitory effect, but its acceptance as primary ...
The best overall survival rates are seen after combined radiation therapy combined with chemotherapy (5-FU + Mitomycin) in ... This "combined modality" approach has led to the increased preservation of an intact anal sphincter, and therefore improved ... Current gold-standard therapy is chemotherapy and radiation treatment to reduce the necessity of debilitating surgery. ... Standard treatment may include radiation therapy, chemotherapy, and surgery. About 8,300 people are diagnosed a year in the ...
... and combined modality therapy such as radiotherapy with surgery, chemotherapy, or immunotherapy. To provide the treatment ... Radiation can be given as a curative modality, either alone or in combination with surgery and/or chemotherapy. It may also be ... In Iran, radiation oncologists, who are trained in non-surgical aspects of oncology (including radiation therapy) directly ... "What to Expect When Having Radiation Therapy". Cancer.Net. 2013-03-22. Retrieved 2020-10-01. (Articles with short description, ...
... combined modality therapies, altered fractionation, cost-effectiveness, and outcomes research. He has run numerous ... Combined modality treatment of tumors of the CNS and thorax, as well as pediatric neoplasms: integrating systemic chemotherapy ... Effects of therapies on cognition and developing methods to improve neurocognitive function. Medical director, the Maryland ... Chair, Brain Tumor Committee, Radiation Therapy Oncology Group. Dr. Mehta's son, Tej Mehta, is currently a Captain in the ...
Others use a "triple modality" combination of external beam radiation therapy, brachytherapy, and hormonal therapy. In advanced ... when surgery or radiation therapy alone is less likely to cure the cancer. Some radiation oncologists combine external beam ... and photodynamic therapy that permit focal therapy by utilizing image guidance. These therapies are still in beginning or ... and external-beam radiation therapy, proton therapy, high-intensity focused ultrasound (HIFU), cryosurgery, hormonal therapy, ...
These two modalities affect not only the cancer affected cells, but also the normal cells Now in AIET, specific types of cells ... has proven that the cell based immunotherapy when combined with conventional treatment the efficacy improves by 20-30%. A ... This is the mechanism by which AIET is effective in cancer therapy. Adoptive Immuno cell therapy of cancer was first introduced ... Autologous immune enhancement therapy (AIET) is a treatment method in which immune cells are taken out from the patient's body ...
... chemoradiation strategies for combined modality therapy, and patient selection criteria. In 2009, she was the recipient of the ... Mitchell conducted and published clinical evidence of the merits of combined-modality treatment. In August 2015, Mitchell was ... With a team of researchers in the NRG Oncology/Radiation Therapy Oncology Group (RTOG), ...
This includes the modalities dance therapy, drama therapy, art therapy, music therapy, writing therapy, among others. This may ... meseron therapy and systemic therapies based on the Ubuntu philosophy. Integrative psychotherapy is an attempt to combine ideas ... multimodal therapy, and therapies for specific disorders including PTSD therapies such as cognitive processing therapy and EMDR ... Psychotherapy (also psychological therapy, talk therapy, or talking therapy) is the use of psychological methods, particularly ...
... optionally combine art-making with basic psychotherapeutic modalities in their treatment. Therapists may better understand a ... Art therapy (not to be confused with arts therapy, which includes other creative therapies such as drama therapy and music ... The last way art therapy is looked at is through the lens of art as therapy. Some art therapists practicing art as therapy ... There are three main ways that art therapy is employed. The first one is called analytic art therapy. Analytic art therapy is ...
Ultrasound therapy: First introduced as a treatment modality in 1992, it involves the application of high-frequency sound waves ... Multidisciplinary approach (HBO + Surgery): Studies have shown support of combining HBO therapy and a surgical approach to ... while combined with debridement. Hyperbaric oxygen therapy (HBO): First described in 1973, HBO was intended to be an adjunctive ... which is likely attributable to improvements in radiation therapy. Radiation therapy destroys cancer primarily by causing DNA ...
A combined therapeutic approach which is at least twice as effective as other therapeutic modalities published to date is ... "Cognitive-behavior therapy for medically unexplained symptoms: A critical review of the treatment literature". Behavior Therapy ... Steele RE, de Leeuw E, Carpenter D. "A novel and effective treatment modality for medically unexplained symptoms" J Pain ... "A novel and effective treatment modality for medically unexplained symptoms". The next best documented approach is cognitive ...
It is clear that strategically integrating immune-based therapies with standard cancer treatment modalities, in particular ... Chemoimmunotherapy is chemotherapy combined with immunotherapy. Chemotherapy uses different drugs to kill or slow the growth of ... whereas systemic therapies (chemotherapy, endocrine therapy, molecularly targeted therapies, and adjunctive therapies ( ... Combination of different therapies in cancer has become a trend, not just between different types of therapies, also multiple ...
Radiation therapy combined with partial surgical resection or radiation therapy alone have been used in cases where the primary ... therapy and chemotherapy to treat LGFMS are limited and this tumor does not appear very sensitive to either treatment modality ...
Surgery, if feasible, is the only curative therapy. If the tumor has metastasized (most commonly, to the liver) and is ... Interferon treatment is also effective, and usually combined with somatostatin analogues. As the metastatic potential of a ... considered incurable, there are some promising treatment modalities, such as radiolabeled octreotide (e.g. Lutetium (177Lu) ...
Palliative treatment consists of radiation therapy usually combined with chemotherapy. The use of tracheostomy as part of ... and if combined modality treatment is used. Treatment of anaplastic thyroid cancer is generally palliative in its intent due to ... Combinatorial therapy that is molecular-based may lead to significant tumor regression, potentially making patients amenable to ... Recent advances show that using a combination of novel targeted therapies, immunotherapy, and surgery, 1 year and 2 year ...
... to evaluate the potential clinical benefit of combining PROSTVAC with different treatment modalities such as hormonal therapies ... Based on non-clinical data supporting the scientific rationale for combination therapy with PROSTVAC, additional clinical ...
... can be treated with radical hysterectomy with removal of the lymph nodes or radiation therapy. Radiation therapy is given as ... Imaging modalities such as ultrasound, CT scan, and MRI have been used to look for alternating disease, spread of the tumor, ... More recently, CIN2 and CIN3 have been combined into CIN2/3. These results are what a pathologist might report from a biopsy.[ ... Larger early-stage tumors (IB2 and IIA more than 4 cm) may be treated with radiation therapy and cisplatin-based chemotherapy, ...
Combining talking and other physical attributions in order to help clients to process trauma that inhibits their day to day ... https://healthjade.net/havening/. {{cite web}}: Missing or empty ,title= (help) "PsychoSensory Modalities". Sole to Soul ... Massage therapy involves kneading different parts of the body with some pressure. This form of touch therapy breaks down tissue ... This type of therapy provides many benefits to the individuals who use it and is based off of using touch, smell, and any other ...
In the UK, it made £123,000 on its opening day, which was more than the combined total of 3 Idiots in its first two days (£ ... He underwent a physical therapy, and in the next month a surgery that made the shooting was delayed until the next month. After ... Analysis of Modality in the Semantic Science of My Name Is Khan]. ISLLAC: Journal of Intensive Studies on Language, Literature ... In January 2010, he had another physical therapy. The Los Angeles schedule began in March 2009. In the next month, the slum ...
Beck, R. & Fernandez, E. (1998). "Cognitive-behavioral therapy in the treatment of anger: A meta-analysis". Cognitive Therapy ... The daily stress combined with slow or no progress with the people under their care can create a high level of frustration. ... He stated that anger is an emotional response to situations, and that anger occurs in three modalities, either cognitive, ... which is primarily based in cognitive-behavioral therapy. Group, family, and relaxation only therapies each contribute to the ...
Some can be described as techniques or modalities. Often surgeons will use two or more of the different techniques below in the ... Schmeller W, Meier-Vollrath I. Tumescent liposuction: a new and successful therapy for lipedema. J Cutan Med Surg. 2006;10(1):7 ... Note that techniques can be combined; for instance one could refer to the procedure as "lymph-sparing, tumescent liposuction ...
"MS therapy trial urged by Manitoba minister". CBC News. Canadian Press. 16 August 2010. "CIHR makes recommendations on Canadian ... The poor reproducibility across studies and diagnostic modalities has led some authors to conclude that CCVSI might be nothing ... Initial difficulty reproducing results connecting MS and CCSVI, combined with reports of secondary effects of the surgical ... "Health minister rejects MS therapy trial". CBC News. 2 September 2010. Weeks C (29 June 2011). "Ottawa to fund clinical trials ...
"A comprehensive review of protein kinase inhibitors for cancer therapy". Expert Review of Anticancer Therapy. 18 (12): 1249- ... Multiple weak bonds between the inhibitor and the enzyme active site combine to produce strong and specific binding. In ... Rapid Method for Determining Inhibition Modality". SLAS Discovery: Advancing Life Sciences R & D. 24 (5): 515-522 (516). doi: ... de Leuw P, Stephan C (April 2018). "Protease inhibitor therapy for hepatitis C virus-infection". Expert Opinion on ...
... and cheap modality for a "first-pass" before the above imaging modalities or surgery is used to confirm the diagnosis. The ... Response to therapy is measured by a reduction in total tumor volume as well as symptomatic relief, reported by the patient. A ... This complication is related to the impact that alpha and beta-adrenoceptor antagonists have on blood vessels combined with the ... As MIBG therapy can destroy the thyroid, protective medications (potassium iodide) are started prior to treatment and need to ...
... associated with radical surgery have prompted to adopt a combined strategy of conservative surgery and radiation therapy to ... More research is needed to establish the role of each treatment modality. "Craniopharyngioma". The Lecturio Medical Concept ... Proton therapy affords a reduction in dose to critical structures compared to conventional photon radiation, including IMRT, ... The close proximity to neighboring eloquent structures poses a particular challenge to radiation therapy. Modern treatment ...
Newer high throughput technologies when combined with advances in imaging modalities such as in vivo optical nanotechnologies ... The final therapy includes using RNA-based approaches to enhance stability, specificity, and efficacy, especially in diseases ... There are currently three classes of therapies that have been utilized in both animal models of disease and in human clinical ... Neuroimmunology is a field combining neuroscience, the study of the nervous system, and immunology, the study of the immune ...
Her work in developing expressive arts therapy expanded upon traditional views of art therapy as pertaining to drawing, ... This combines multiple forms of self-expression with an end goal of achieving new levels of personal development. The person- ... painting, and sculpture to include other modalities of art including dance, movement, poetry and drama into the therapeutic ... Kim, Sunhee (2010). "A Story of a Healing Relationship: The Person-Centered Approach in Expressive Arts Therapy". Journal of ...
The idea of combining/integrating brain signals from multiple individuals was introduced at Humanity+ @Caltech, in December ... The biggest impediment to BCI technology at present is the lack of a sensor modality that provides safe, accurate and robust ... The results could be presented to physicians and therapists, which could lead to a revised diagnosis and therapy. In addition, ... Imaging studies combined with EEG-based BCI systems hold promise for investigating neuroplasticity during motor recovery post- ...
A study was conducted regarding the recidivism rate of inmates receiving MMT (Methadone Maintenance Therapy). This therapy is ... These dehumanizing acts, combined with learned violent behavior, are implicated in higher recidivism rates. Two studies were ... state and federal judges have sentenced offenders to learn the Transcendental Meditation program as an anti-recidivism modality ... McMillan, Garnett P, 2008, "The effect of a jail methadone maintenance therapy (MMT) program on inmate recidivism", Addiction, ...
Treatment modalities can, and often are, utilized concurrently so that an individual may pursue psychological therapy (i.e., ... A promising innovative approach to improving recovery rates for the treatment of GAD is to combine CBT with motivational ... Cognitive behavioral therapy (CBT) is widely regarded as the first-line psychological therapy for treating GAD. Additionally, ... EFT can incorporate numerous practices such as experimental therapy, systemic therapy, and elements of CBT to allow individuals ...
"Gene Therapy for X-Linked Severe Combined Immunodeficiency: Where Do We Stand?". Human Gene Therapy. 27 (2): 108-116. doi: ... Most treatment is therefore passive and palliative, and falls into two modalities: managing infections and boosting the immune ... VST therapy uses active donor T-cells that are isolated from alloreactive T-cells which have proven immunity against one or ... T-lymphocyte therapies are still in the experimental stage; few are even in clinical trials, none have been FDA approved, and ...
Bicalutamide levels during therapy with bicalutamide (R)-Bicalutamide levels after a single 5 to 80 mg dose of (R)-bicalutamide ... Labrie F (January 2015). "Combined blockade of testicular and locally made androgens in prostate cancer: a highly significant ... is significantly more effective than either modality alone in the treatment of prostate cancer. Bicalutamide monotherapy has ... It reaches maximal constant levels after 4 to 12 weeks of therapy. Bicalutamide shows extensive plasma protein binding, mainly ...
Combining the MPI characterization of the person with their IASP five-category pain profile is recommended for deriving the ... Bonica JJ (1990). "History of pain concepts and therapies". The management of pain. Vol. 1 (2 ed.). London: Lea & Febiger. p. 7 ... which conceived of pain not as a unique sensory modality, but an emotional state produced by stronger than normal stimuli such ... Rubinstein SM, Terwee CB, Assendelft WJ, de Boer MR, van Tulder MW (September 2012). "Spinal manipulative therapy for acute low ...
Antidepressants should be used in conjunction with exposure as a form of self-help or with cognitive behaviour therapy. A ... Videoconferencing psychotherapy (VCP) is an emerging modality used to treat various disorders in a remote method. Similar to ... Individuals without agoraphobia are able to maintain balance by combining information from their vestibular system, their ... A related exposure treatment is in vivo exposure, a cognitive behavioral therapy method, that gradually exposes patients to the ...
In contrast and by distinction, audio therapy is provided as a self-service modality, through which the listener is purported ... the Hirsch, C. R., Clark, D. M., and Mathews, A., Imagery and interpretations in social phobia: Support for the combined ... One such discipline is cognitive behavioral therapy. Unlike music therapy, but similar to audio therapy, the most important ... as well as art therapy, music therapy, and dance therapy. Although the means by which the mind affects the body is largely ...
This later included internal passport controls, which when combined with individual city Propiska ("place of residence") ... "shock therapy" had little to do with future economic growth. A 2009 Pew Research Center poll showed that 72% of Hungarians and ... modality. While the Soviet system strove for a dictatorship of the proletariat, there was little existing proletariat in many ...
However, it is not possible to fully encode a spoken language in the manual modality. Numerous systems of manually encoded ... Due to hearing loss, the spoken language acquisition process is delayed until such technologies and therapies are used. The ... and combining them to do everything we do?" He explained in his writings that the deaf simply have no way of expressing and ... Due to the visual/manual modality, these differences can assist in distinguishing among universal aspects of language ...
Adult dissociation when combined with a history of child abuse and otherwise interpersonal violence-related posttraumatic ... The authors of this article included leading thinkers of their time - John G. Watkins (who developed ego-state therapy) and ... Both hypnotic suggestibility and dissociation tend to be less mindful, and hypnosis is used as a treatment modality for ... Bowers MK, Brecher-Marer S, Newton BW, Piotrowski Z, Spyer TC, Taylor WS, Watkins JG (April 1971). "Therapy of multiple ...
... where the therapy has survival benefit and can be curative). It is also common to combine radiation therapy with surgery, ... Ohno T, Okamoto M (June 2019). "Carbon ion radiotherapy as a treatment modality for paediatric cancers". The Lancet Child & ... Radionuclide therapy (also known as systemic radioisotope therapy, radiopharmaceutical therapy, or molecular radiotherapy), is ... Combining radiation therapy with immunotherapy is an active area of investigation and has shown some promise for melanoma and ...
Alternative Therapies in Health and Medicine. 21 (3): 32-40. PMID 25691329. Kramp ME (October 2012). "Combined manual therapy ... Pediatric physical therapy assists in the early detection of health problems and uses a variety of modalities to provide ... heat therapy, and ultrasound therapy are not as effective, and thus not recommended. Studies also show physical therapy is ... This is especially important because combining physical therapy and psychotherapy can improve neurological status of the ...
The CJD Therapy Advisory Group to the UK Health Departments advises that data are not sufficient to support claims that ... The method combines amplification with a novel technology called surround optical fiber immunoassay (SOFIA) and some specific ... Brain MRI is the most useful imaging modality for changes related to CJD. Of the MRI sequences, diffuse-weighted imaging ... "Use of Pentosan Polysulphate in the treatment of, or prevention of, vCJD". Department of Health:CJD Therapy Advisory Group. ...
Brain radiation therapy (discussed in Radiation therapy) is often used in addition to surgical removal of tumors. Chemotherapy ... Motor skill - a learned sequence of movements that combine to produce a smooth, efficient action in order to master a ... Specifically, it deals with how the brain processes multiple sensory modality inputs into usable functional outputs. See also ... See, for example: Cognitive rehabilitation therapy, Rehabilitation (neuropsychology), and Cognitive Remediation Therapy. ...
A combined positron emission tomography (PET)-electron paramagnetic resonance imaging (EPRI) system: initial evaluation of a ... March 2019). "Oxygen-Guided Radiation Therapy." International Journal of Radiation Oncology, Biology, Physics 103, no. 4 (15 ... The main advantage of ERI modality is the ability of mapping the tissue microenvironment parameters e.g. oxygen partial ...
Behavior Therapy, 1971, 2, 498-510 Novaco, R. W. (1977). Stress inoculation: A cognitive therapy for anger and its application ... Combining PET and magnetic resonance imaging (MRI), subjects viewing a moving checker board pattern verses a stationary checker ... who question and debate localization and modality specialization within the brain. McIntosh's research suggests that human ... may play a role Research in the study of brain function can also be applied to cognitive behaviour therapy. As therapy becomes ...
Non-synergy of PD-1 blockade with T-cell therapy in solid tumors John S Davies, Farrah Karimipour, Ling Zhang, Nisha Nagarsheth ... Immunotherapy combining tumor and endothelium cell lysis with immune enforcement by recombinant MIP-3α Newcastle disease virus ... Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic ...
Combined Modality Treatment Neoadjuvant Therapy. Robert A. Wolff, MD, MD Anderson Cancer Center reviewed the role of ... Neoadjuvant therapy consists of systemic chemotherapy with or without the addition of radiation therapy. Neoadjuvant therapy ... Pre-radiation therapy imaging is strongly recommended to rule out systemic failure before the initiation of therapy.[37,38] ... There is no clearly superior adjuvant therapy regimen. The role of adjuvant radiation therapy is controversial. Patients at ...
"Combined Modality Therapy" by people in this website by year, and whether "Combined Modality Therapy" was a major or minor ... "Combined Modality Therapy" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Combined Modality Therapy" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Combined Modality Therapy". ...
Combined modality therapy of gastrointestinal tract cancer / P. Schlag, P. Hohenberger, U. Metzger (eds.) Contributor(s): ... Combined modality therapyNLM classification: WI 149 Tags from this library: No tags from this library for this title. Log in to ...
Evolution of Combined Modality Therapy for Stage III Non-Small-Cell Lung Cancer. July 02, 2000 ... A number of randomized clinical trials and meta-analyses now support the conclusion that combined modality regimens that ...
Combined Modality Therapy. en_US. dc.title. Combination therapy in malaria: orientations and options for the African Region. en ... Combination therapy in malaria: orientations and options for the African Region. dc.contributor.author. Sukwa, Thomas. en_US. ...
She was treated with combined modality therapy. * A 55-year-old female with tongue burning for 15 months. The history for ... 54] Attempting combinations of therapies may be appropriate; in particular, cognitive therapy may be synergistic with other ... There is some emerging data to support the use of laser therapy. For example, a literature review by Al-Maweri et al found that ... A burning therapy for burning mouth syndrome: preliminary results with the administration of topical capsaicin. J Biol Regul ...
Nonetheless, further research is needed to develop therapies that would optimize outcomes and … ... support of the original reviews conclusions as to the efficacy and generalizability of psychological and behavioral therapies ... Behavior Therapy* * Cognitive Behavioral Therapy* * Combined Modality Therapy * Comorbidity * Cross-Sectional Studies ... Stimulus control therapy, relaxation, paradoxical intention, sleep restriction, and cognitive-behavior therapy. ...
Advancing Combined Modality Therapy for Early-Stage, Screen-Detected Disease: Adjuvant/Neoadjuvant Therapy. By: David ... Home Lung Cancer Screening Advancing Combined Modality Therapy for Early-Stage, Screen-Detected Disease: Adjuvant/Neoadjuvant ...
Combined-Modality Therapy for Locoregionally Advanced Head and Neck Cancer. October 01, 1999 ...
Combined Modality Therapy. EN. dc.subject. Cost of Illness. EN. dc.subject. Risk Factors. EN. ...
... of 1-cm distal margin after restorative rectal cancer resection with sharp mesorectal excision and preoperative combined- ... BACKGROUND: Preoperative combined-modality therapy (CMT) for rectal cancer allows a sphincter-sparing procedure in some ... margin after restorative rectal cancer resection with sharp mesorectal excision and preoperative combined-modality therapy. ...
I am/have/hadcombined modality therapy. I am/have/hadlow grade glioma. ... Personalized Radiation Therapy for GBM The study is a pilot study to estimate the efficacy of personalized dose-escalation ... After such therapy, most patients experiment recurrence and few therapeutic option are available. Despite such … ... The current treatment relies on surgical resection of gross tumor followed by radiochemotherapy and adjuvant therapy with ...
Combined Modality Therapy * Congenital Anomalies of the Head and Neck * Craniopharyngioma * Cricoid Split ... Penn Medicines programs and centers combine doctors from many disciplines to coordinate care from start to finish. Dr. Basu is ... HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1alpha/ERRalpha axis JCI Insight 7 (18): 2022 ... his laboratory facilitates the use of these tumors removed from patients to advance the science of cancer therapy. ...
Minsky, B. D. Combined-modality therapy of rectal cancer with irinotecan-based regimens. Oncology (Huntingt.) 18, 49-55 (2004) ...
... etiologies and treatment modalities in Ecuador. We propose that the sample distribution fits the expected one, and that there ... and biologic therapy). These therapeutic modalities apply only to treatment initiation; no follow up or treatment modifications ... The prevalence of combined use of first- and second-generation H1 antihistamines, or the use of a first-generation H1 ... The purpose of this study was to identify chronic urticaria (CU) etiologies and treatment modalities in Ecuador. We propose ...
... triple modality. The results revealed that all the four domains of QL of women having adjuvant therapy (groups 2, 3, or 4) were ... Triple modality predicted the worst QL. QL measures should be incorporated with the traditional end points for evaluation of ... Triple modality adversely affected global QL the most compared to radiotherapy or chemotherapy; radiotherapy had significantly ... ABSTRACT The impact of breast cancer therapy on the quality of life (QL) of Egyptian women was studied. Patients were divided ...
Hodgkinss disease and late effects of radiation and combined modality therapy. Radiation sensitizers. Hypoxic cell cytotoxins ... Combined Modality Treatment of Cancer. Late Effects of Treatment. Genetic Effects of Cancer. Rhabdomyosarcoma. Hodgkins Disease ... Targeted therapy has markedly improved outcomes for pediatric CML, while raising a number of clinical questions, including the ... Targeted therapy has markedly improved outcomes for pediatric CML, while raising a number of clinical questions, including the ...
Photodynamic Therapy: Photodynamic therapy combines a photosensitizer, such as Photofrin®, with red laser light to destroy ... Combining Other Agents with BCG: BCG is the most active treatment modality for superficial bladder cancer. In general, adding ... Adjuvant therapy is additional treatment that increases the effectiveness of a primary therapy. The goal of adjuvant therapy is ... Photodynamic therapy appears to be a safe and effective treatment for refractory carcinoma in situ or recurrent papillary ...
Estrogens are administered in various modalities including injection, transdermal patch, and oral tablets.[16] ... an estrogen is combined with an antiandrogen to suppress and block testosterone.[15] This allows for demasculinization and ... Transgender hormone therapy, also called hormone replacement therapy (HRT) or gender-affirming hormone therapy (GAHT), is a ... Feminizing hormone therapy[edit]. Main article: Feminizing hormone therapy. Feminizing hormone therapy is typically used by ...
1992) Combined modality therapy for primary CNS lymphoma. J Clin Oncol 10:635-643. ... Seven patients with complete response after therapy relapsed, and seven died (five disease and two therapy related). Kaplan- ... after initiation of therapy. One patient (13) developed similar changes 1 month after initiation of combined intraventricular/ ... without intraventricular therapy because of extensive confluent white matter changes, which had developed under initial therapy ...
Combined Modality Therapy. Tevyaw TOL, Colby SM, Tidey JW, Kahler CW, Rohsenow DJ, Barnett NP, Gwaltney CJ, Monti PM. ... Alcohol Drinking/*epidemiology/prevention & control/*therapy. Barnett NP, Tevyaw TOL, Fromme K, Borsari B, Carey KB, Corbin WR ...
By combining modalities, I blend evidence-based therapies with a holistic approach. ... What method of therapy is right for me? When it comes to treatment methods, theres no right way. Each method of therapy can ... Offering a range of healing modalities including EMDR, narrative therapy, psychodrama and emotion release work. As a registered ... Finding a psychologist or therapist who is a good fit for you is the most important step to discovering what type of therapy, ...
Combined Modality Therapy, Pathological Conditions, Signs and Symptoms, Drug Therapy, Pharmacologic Actions, Drug Therapy, ... Physical Therapy Modalities, Antineoplastic Combined Chemotherapy Protocols, Ethics, Research, Biomedical Research, 50053, ...
Combined modality therapies (1) * Molecular targets of radiation response (1) * Normal tissue response to radiation (1) ... Targeting the P53 Protein for Cancer Therapies: The Translational Impact of P53 Research ...
Energy healing complements many other forms of treatments and therapies. Combining holistic therapies, like Quantum-Touch, with ... Quantum-Touch is a powerful energy healing modality that works with Life Force Energy -- a universal vibration of love and well ... All modalities can work together to effectively support, balance, and restore our well-being. ... Energy Healing Works with Almost Every Other Type of Healing Modality. ...
Combined Modality Therapy *Dietary Consultation (provided by Home & Community Health Services) * Community Cancer Prevention ... For Radiation Therapy:. 860 272-3000. For North Central Oncology Hematology:. 860 763-4027. For Cancer Center Coordinator:. 860 ... The linear accelerator, shown above, is used to conduct radiation therapy at Phoenix Community Cancer Center. This service is ... From radiation therapy to medical oncology and from support groups to an oncology resource library, PCCC offers the full ...
Sometimes we choose to combine different types of modalities of treatments. And so you really need everybody at the table to ... A: For patients with brain metastases, there are three major types of treatments: surgery, radiation therapy and some sort of ... And then the medical oncologist provides the systemic therapy or recommendation. So all of these specialties are very important ... systemic treatment, whether its chemotherapy or targeted therapy. When we look at patients who have a new diagnosis or ...
Combined Modality Therapy * Cytoreduction Surgical Procedures / adverse effects* * Female * Follow-Up Studies ...
  • Determination of the QL of breast cancer patients under different therapeutic modalities provides a comprehensive description of their potential side-effects from the patient's perspective. (who.int)
  • 1 8 Here we report on the therapeutic results of 20 patients with PCNSL enrolled in a pilot study evaluating the efficacy and toxicity of a novel combined intraventricular and systemic chemotherapy regimen without radiotherapy. (bmj.com)
  • This review article discusses PET agents, other than 18 F-FDG, with the potential to monitor the response to therapy before, during, or after therapeutic intervention. (snmjournals.org)
  • Percussion therapy can be used in a combination of therapeutic massages to relieve muscle soreness. (articlecity.com)
  • Fortunately, today's field of counselling recognizes this individuality and has broadened its modalities to include a variety of therapeutic approaches to address diverse needs and ways of expressing difficulties. (ccpa-accp.ca)
  • Other certified counsellors have specialized training in the intentional therapeutic use of arts-based modalities such as art therapy, drama therapy, music therapy, dance/movement therapy, sandplay therapy, poetry therapy and expressive arts therapies. (ccpa-accp.ca)
  • Appropriate characterization of vitiligo type, consideration of disease extent and duration, and efficacy of prior therapies can guide management and maximize treatment efficacy.Latanoprost was documented to stimulate prostaglandin E2(PGE2) formation, and repigmentation is likely to be induced in part by endogenous PGE2 which acts as a melanogenic stimulator.Narrow band UVB rays are one of the safest and most effective therapeutic modalities of vitiligo. (ejmcm.com)
  • They also utilize therapeutic modalities combined with a comprehensive therapy program for strengthening, balance training, pain reduction, wound-healing, urinary incontinence, and increasing range of motion. (timberlinehealth.com)
  • Metacure: Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volum. (dana-farber.org)
  • Aim: Systemic chemotherapy is a part of multi-modality treatment in patients with stage II-IV rectal cancer. (altinbas.edu.tr)
  • Vitrea™ Advanced Visualization software is a multi-modality system providing comprehensive applications in a variety of IT environments. (medical.canon)
  • Five treatments met criteria for empirically-supported psychological treatments for insomnia: Stimulus control therapy, relaxation, paradoxical intention, sleep restriction, and cognitive-behavior therapy. (nih.gov)
  • Energy healing complements many other forms of treatments and therapies. (quantumtouch.com)
  • Combining holistic therapies, like Quantum-Touch, with conventional medical treatments can help you optimize your health and well-being. (quantumtouch.com)
  • For patients with brain metastases, there are three major types of treatments: surgery, radiation therapy and some sort of systemic treatment, whether it's chemotherapy or targeted therapy. (curetoday.com)
  • Sometimes we choose to combine different types of modalities of treatments. (curetoday.com)
  • Here, we evaluate a further 10 agents for which no clinical trials have (yet) been carried out but there are promising data from in vivo and/or in vitro studies including experiments involving combined treatments with gemcitabine. (lse.ac.uk)
  • She has also presented on the use of play therapy, Theraplay and attachment informed treatments to heal intergenerational trauma. (theraplay.org)
  • In addition to traditional surgical and non‑surgical treatment, combined treatments are more effective for patients with distant metastatic melanoma. (spandidos-publications.com)
  • Studies have shown that ICIs combined with radiotherapy (RT) or anti‑angiogenic therapy can have a synergistic effect in certain tumor treatments, normalizing blood vessels and enhancing immune responses. (spandidos-publications.com)
  • But when conventional treatments do not produce the desired results of reduced pain and return of function, alternative modalities such as acupuncture may be helpful. (ispub.com)
  • Physical therapy treatments are performed by our in-house physical therapist or physical therapy assistant. (rockcanyonrehab.com)
  • The rapidly expanding field of cell and gene therapies (CGT) could revolutionize curative treatments. (biophorum.com)
  • For these patients, alternative modalities are available to assist in the control of pain. (ispub.com)
  • Durvalumab plus tremelimumab alone or in combination with low-dose or hypofractionated radiotherapy in metastatic non-small-cell lung cancer refractory to previous PD(L)-1 therapy: an open-label, multicentre, randomised, phase 2 trial. (jefferson.edu)
  • VMM is usually treated by means of radiotherapy (RT) combined with chemotherapy after surgery. (spandidos-publications.com)
  • It had substantial changes com- diotherapy [12], and chemotherapy-combined radiotherapy pared to the previous edition of classification published in 2007. (bvsalud.org)
  • These updated findings provide additional evidence in support of the original review's conclusions as to the efficacy and generalizability of psychological and behavioral therapies for persistent insomnia. (nih.gov)
  • A number of clinical studies have demonstrated the efficacy of preoperative chemoradiation therapy with 5-fluorouracil (5-FU)-based regimens in decreasing local recurrences and improving survival and the likelihood of sphincter preservation. (elsevier.com)
  • This Phase II, multicenter, randomized, double-blind, placebo-controlled trial was designed to estimate the efficacy and characterize the safety of bevacizumab when combined with carboplatin + paclitaxel chemotherapy compared with carboplatin + paclitaxel chemotherapy alone in patients with previously untreated metastatic melanoma. (stanford.edu)
  • A number of studies conducted with the approach found it to be a highly effective treatment for borderline personality , and research further developing schema therapy and demonstrating its efficacy continues today. (goodtherapy.org)
  • Overall, these sequelae have prompted a search for new regimens that are able to combine high efficacy with low toxicity, and to preserve fertility in young adults. (mhmedical.com)
  • This agent has potent anti-tumor efficacy in mono- and combination therapy in a broad range of cancers. (newdrugapprovals.org)
  • Surgery, radiation therapy, chemotherapy and hormonal therapy make up the standard armamentarium of breast cancer therapy either alone or in combination. (who.int)
  • Treatment failure can prompt a dose increase of up to fourfold according to European guidelines or, in the case of the US guidelines: addition of another second-generation antihistamine, combination therapy with a first- and second-generation H1 antihistamine, or the addition of a leukotriene receptor antagonist as the next step. (springer.com)
  • Although 5-FU has been the standard drug used in combination with radiation therapy for many years, new effective drugs including capecitabine, raltitrexed, irinotecan and oxaliplatin have been recently investigated in combination with radiation therapy in the preoperative setting. (elsevier.com)
  • Finally, as a special case of combination therapy, we highlighted synergistic drug combinations involving gemcitabine with "repurposed" aspirin or metformin. (lse.ac.uk)
  • The clinical research program includes translation of preclinical work performed in the Radiobiology Section at Stanford, new drug development, the development of novel combination therapy, chemoprevention, and the integration of biological response modifiers into combined modality treatment. (stanford.edu)
  • The patient's primary tumor and distant metastases improved after combination therapy. (spandidos-publications.com)
  • The combination therapy successfully improved the patient's prognosis and prolonged the patient's overall survival. (spandidos-publications.com)
  • This reported case, together with other successful cases reported in the literature, provide useful references for the application of combination therapy to treat MM. (spandidos-publications.com)
  • DVT Compression therapy is used in combination with specially designed therapy wraps to transfer pressure to the calf or foot using compressed air. (metromedicalus.com)
  • If prescribed, Cold therapy can be used in combination with Pneumatic Compression therapy. (metromedicalus.com)
  • Background: Combined multimodal treatment (CMT) is the preferred treatment for anal squamous carcinoma with radical surgery reserved for treatment failure. (bvsalud.org)
  • Adequacy of 1-cm distal margin after restorative rectal cancer resection with sharp mesorectal excision and preoperative combined-modality therapy. (duke.edu)
  • BACKGROUND: Preoperative combined-modality therapy (CMT) for rectal cancer allows a sphincter-sparing procedure in some individuals who would otherwise require an abdominoperineal resection. (duke.edu)
  • The treatment approach integrates elements from cognitive behavioral therapy , attachment theory, and a number of other approaches, expanding on CBT through exploration of emotions, maladaptive coping methods, and the origin of mental health concerns. (goodtherapy.org)
  • Dr. Jeffrey Young began the development of schema therapy in the mid-1980s after he found cognitive behavioral therapy to be less helpful for some individuals than others, particularly those with chronic characterological concerns. (goodtherapy.org)
  • Because these situations require different therapies, accurate prenatal diagnosis and expert fetal and maternal surveillance is critical to maximize the chances for a favorable outcome. (hopkinsmedicine.org)
  • We intuitively integrate our professional experience & continuing education with various bodywork tools & massage therapy modalities to work with you to achieve your desired outcome. (massagebook.com)
  • Non-invasive outcome measures that demonstrate early response to novel therapies are urgently required. (ncl.ac.uk)
  • Combining therapies can 'amp up' or enhance the outcome experience. (debrareis.com)
  • Before these treatment regimens were available, 90% of patients with Hodgkin lymphoma died within 2-5 years, whereas 85%-90% are now curable with modern therapy. (mhmedical.com)
  • [ 4 ] He noted that patients who are candidates for preoperative, neoadjuvant therapy should have a tissue diagnosis. (medscape.com)
  • in addition, nonsurgical palliative therapy for these patients is now highly successful and durable. (medscape.com)
  • Trends and variations in postmastectomy radiation therapy for breast cancer in patients with 1 to 3 positive lymph nodes: A National Cancer Data Base analysis. (jefferson.edu)
  • As a surgeon-scientist, his laboratory facilitates the use of these tumors removed from patients to advance the science of cancer therapy. (pennmedicine.org)
  • QL measures should be incorporated with the traditional end points for evaluation of treatment and patients given health education on the effects of each therapy. (who.int)
  • Patients who received postoperative endocrinal therapy (tamoxifen) were excluded because of their small number (4 patients only). (who.int)
  • I am passionate about the intersection between clinical care and clinical research, and committed to understanding the long-term effects of childhood cancer therapies over the course of our patients' lifetimes. (stanford.edu)
  • The Standards of Care for the Health of Transsexual, Transgender, and Gender Nonconforming People (SOC) require that patients seeking gender-affirmation hormone therapy be evaluated for gender dysphoria by either a mental health professional or hormone provider who is qualified in the area of transgender care. (wikipedia.org)
  • The combined solution will support the growing trend toward minimally invasive spinal and cranial approaches that spare healthy tissue, reduce pain, and speed recovery for patients. (prnewswire.com)
  • In a large retrospective cohort from the MD Anderson Cancer Center, the clinical features of 981 oropharyngeal patients who underwent primary radiation therapy were described. (uofmhealth.org)
  • The specific aims of are 1) to develop an intra-cardiac hybrid system to perform HIFU, real-time temperature and lesion size monitoring using SWI, 2) Validate and optimize the imaging/therapy system in an animal model and 3) Demonstrate the feasibility of real-time RF ablation monitoring in patients using SWI. (europa.eu)
  • Combined modality therapy (CMT) -- chemotherapy plus radiation therapy -- was associated with improved survival in young Hodgkin lymphoma patients compared with chemotherapy alone, an observational study found. (medpagetoday.com)
  • The authors noted in the finding that patients ages 1 to 13 years derived the least additional benefit from adding RT is of particular interest, as these patients are the most "vulnerable" to late effects from radiation therapy. (medpagetoday.com)
  • As multiple disparities to the use of combined modality therapy have been identified through this work, future studies should address improving access to care for all pediatric patients," Parikh said. (medpagetoday.com)
  • Patients either received no further therapy or ipsilateral (lumpectomy side) radiation therapy to a dose of 5000 centi-Gray or rads. (oncolink.org)
  • The percent incidence of ipsilateral breast tumor (treated same breast) as the site of first failure was higher with lumpectomy alone patients versus the lumpectomy and radiation therapy group. (oncolink.org)
  • A total of 9 lumpectomy and radiation therapy patients and 6 lumpectomy alone had distant failures as first or subsequent sites of recurrence. (oncolink.org)
  • However, whether ICIs combined with RT and anti‑angiogenic therapy can benefit patients with distant metastatic vaginal melanoma remains unclear. (spandidos-publications.com)
  • Nearly two-thirds of all cancer patients receive radiation therapy at some point during treatment. (northside.com)
  • While patients, understandably, are looking for relief, there are often no quick fixes and little definitive evidence to guide therapy. (acpinternist.org)
  • But physicians can find success by listening to patients' preferences, communicating expectations, and combining different modalities, according to experts. (acpinternist.org)
  • Advanced-stage disease is generally treated with chemotherapy alone, with radiation therapy reserved for selected patients. (medscape.com)
  • We have a full-time in-house therapy team - not outside contractors or agencies - so our patients get to know their therapists, and vice-versa. (timberlinehealth.com)
  • Our therapy team is passionate about bringing the latest techniques and programs to our patients. (timberlinehealth.com)
  • At the heart of our therapy programs is a deep appreciation for, and understanding of, the special needs of our more mature patients. (timberlinehealth.com)
  • Our integrated cognitive program combines a standardized functional cognitive assessment with our patients' "life footprint" to help us develop a comprehensive understanding of each individual under our care. (timberlinehealth.com)
  • When the plan is to stay in our facility once the therapy program is complete, we make sure that we work side-by-side with our nursing staff so that our patients can continue to function at their highest possible level to preserve their independence and participation. (timberlinehealth.com)
  • What new therapies are on the horizon for patients with Waldenström macroglobulinemia (WM)? (powerfulpatients.org)
  • And those drugs actually work often for patients who progress on initial therapy with ibrutinib or zanubrutinib. (powerfulpatients.org)
  • But the other immunotherapies that are up and coming - which I think are important for patients to know about - one is CAR-T cell therapy. (powerfulpatients.org)
  • And what CAR T-cell therapies do is patients can collect from their bloodstream - the physicians can collect T cells and then they modify those T-cells in a way so that they'll recognized the cancer and attack the cancer. (powerfulpatients.org)
  • Although patients diagnosed with or receiving therapy for cancer were excluded from the initial vaccine trials, emerging evidence now supports vaccine safety with potentially diminished immune response in this group. (ecancer.org)
  • As anticipated, poor serologic responses have been particularly observed among patients receiving B-cell depleting therapies. (ecancer.org)
  • Medical therapy after conservative surgery is recommended for patients with pelvic pain to reduce recurrence of pain and reoperation rates. (exxcellence.org)
  • In premenopausal patients undergoing hysterectomy with bilateral oophorectomy for endometriosis, estrogen therapy (ET) is recommended to reduce symptoms of hypoestrogenism, reduce bone loss, and decrease cardiovascular morbidity. (exxcellence.org)
  • By combining the collective wisdom of our highly-trained physicians, physiatrists and surgeons, we're equipped to restore our patients to the fullest possible quality of life. (eternalhospital.com)
  • Combined modality therapy of gastrointestinal tract cancer / P. Schlag, P. Hohenberger, U. Metzger (eds. (who.int)
  • The impact of breast cancer therapy on the quality of life (QL) of Egyptian women was studied. (who.int)
  • Hence, the present study was undertaken to determine the effects of the different modalities of treatment on the QL of Egyptian women with early breast cancer. (who.int)
  • Standard treatment of superficial bladder cancer is surgical removal and adjuvant therapy to decrease the risk of recurrent cancer or progression to more invasive disease. (cancerconnect.com)
  • Since the risk of developing invasive bladder cancer never goes away, it is important to have frequent follow-up examinations (cystoscopy) no matter what form of therapy is selected. (cancerconnect.com)
  • The linear accelerator, shown above, is used to conduct radiation therapy at Phoenix Community Cancer Center. (johnsonhealthnetwork.com)
  • From radiation therapy to medical oncology and from support groups to an oncology resource library, PCCC offers the full spectrum of cancer care services. (johnsonhealthnetwork.com)
  • The researchers hope to learn if combining the study drugs with surgery and radiation will get rid of the cancer from participants' prostates and reduce their prostate-specific antigen (PSA) to an undetectable level. (dana-farber.org)
  • Given the breadth of cancer biology and the targets to be explored, the future prospects for monitoring therapy with novel PET agents that are currently in preclinical development are discussed. (snmjournals.org)
  • In addition, Dr. Jhingran is heavily involved with the Radiation Therapy Oncology Group (RTOG) and Gynecologic Oncology Group (GOG), in the development of patient care studies to treat gynecologic cancers and has been the national Principal Investigator of several studies, including a phase III study in cervical cancer. (mdanderson.org)
  • Clinical investigations focus on head and neck cancer with a particular interest in combined modality therapy. (stanford.edu)
  • Lumpectomy and Radiation Therapy for the Treatment of Intraductal Breast Cancer: Findings from National Surgical Adjuvant Breast and Bowel Project. (oncolink.org)
  • The Northside Hospital Cancer Institute offers a comprehensive array of treatment modalities. (northside.com)
  • Radiation therapy uses high-energy X-rays to destroy cancer cells and prevent cancer from returning. (northside.com)
  • Our radiation oncology locations throughout the state offer a wide variety of radiation therapy options to treat all types of cancer including external radiation (or external beam radiation) modalities and internal radiation (or brachytherapy) modalities. (northside.com)
  • Combined Modality Bladder-Sparing Therapy for Muscle-Invasive Bladder Cancer: How (Should) We Do It? (bvsalud.org)
  • Several concerns can face a person who receives a cancer diagnosis, and supportive therapies may bring balance and comfort in challenging situations. (debrareis.com)
  • Gentle Movement Therapy - there is growing evidence of the importance of physical activity for cancer survivors, including gentle stretching and walking to reduce fatigue and provide greater flexibility and strength. (debrareis.com)
  • To learn more about holistic therapies with cancer survivors, check out my article, Nurses Integrate Holistic Therapies for Patient Comfort in Outpatient Oncology , published in Beginnings, an American Holistic Nurses Association publication. (debrareis.com)
  • The American College of Radiology recommends ultrasonography as the first imaging modality in men younger than 25 years because breast cancer is highly unlikely. (cancer.gov)
  • The GISTAR study aims to determine whether H. pylori eradication combined with endoscopic screening of atrophic gastritis reduces mortality from gastric cancer among people aged 40-64 years ( https://www.gistar.eu ). (who.int)
  • The results revealed that all the four domains of QL of women having adjuvant therapy (groups 2, 3, or 4) were significantly altered compared to those who underwent mastectomy alone. (who.int)
  • In the present review we summarize the results of adjuvant therapy. (elsevier.com)
  • I knew that I could count on bodywork modalities to be of some help, and they were indeed palpably helpful to my regeneration. (movnat.com)
  • Combined Modality Therapy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (jefferson.edu)
  • Find the best Cupping & Massage Therapy near me in Centennial Colorado! (massagebook.com)
  • Text us directly for rapid response, expanded massage therapy scheduling options available. (massagebook.com)
  • What contribution can massage therapy be for your health and well being? (massagebook.com)
  • Your body is conscious intelligence & we work for you as a catalyst through massage therapy and energetic body processes. (massagebook.com)
  • LaVida Massage is a massage therapy service that combines custom massage therapy with a variety of modalities. (drugster.info)
  • The Massage Therapist will consult with the guest before every session to find out which modality will best suit their needs. (drugster.info)
  • These options include chiropractic care, physical therapy, massage therapy, and modalities that fall under the auspices of complimentary and alternative medicine (CAM), such as acupuncture. (ispub.com)
  • N-Touch Raindrop combines the science of aromatherapy using techniques of Vita flex, reflexology, and massage while applying essential oils, which are applied to the spine and feet to bring harmony, structural and electrical alignment to the body. (bhammassagecouple.com)
  • General treatment modalities include radiation therapy, induction chemotherapy, salvage chemotherapy, and hematopoietic stem cell transplantation. (medscape.com)
  • Relaxation Therapies - may include modalities such as guided imagery and energy therapy like Healing Touch. (debrareis.com)
  • Vitiligo may appear at any age and affect both sexes.Treatment can be challenging, though available modalities of therapy include pharmacologic, surgical, and phototherapy. (ejmcm.com)
  • Conservative therapy may include fulguration, laser ablation or excision of endometrial implants, lysis of adhesions, repair of tubal damage, uterosacral nerve ablation, and presacral neurectomy. (exxcellence.org)
  • First line therapies include either combined hormonal contraceptives or continuous progestins. (exxcellence.org)
  • Historically, many health centers required a psychiatric evaluation and/or a letter from a therapist before beginning therapy. (wikipedia.org)
  • Many healthcare organizations, such as outpatient oncology centers, integrate holistic modalities into a care plan for well-being. (debrareis.com)
  • No universally accepted diagnostic criteria, laboratory tests, imaging studies or other modalities definitively diagnose or exclude burning mouth syndrome (BMS). (medscape.com)
  • The multi-room suites incorporate diagnostic quality high-field MR, CT and angio modalities accessed effortlessly in the operating room setting. (prnewswire.com)
  • This training will address the benefits and intricacies of using EMDR therapy and Theraplay, as these two powerful approaches can compliment and benefit each other in the treatment of highly traumatized children. (theraplay.org)
  • Ana is the author of EMDR Therapy and Adjunct Approaches with Children: Complex Trauma, Attachment and Dissociation and several books, book chapters and articles on the use of EMDR therapy with children and adolescents. (theraplay.org)
  • He combined concepts from Gestalt , object relations , constructivist , and psychoanalytic approaches into a unified modality that focused on the particular strengths of each method. (goodtherapy.org)
  • Holistic therapies can be helpful for anxiety, stress, and discomfort. (debrareis.com)
  • Nurses or therapists often provide holistic therapies with special education and training in a specific modality. (debrareis.com)
  • The holistic modalities identified - relaxation therapy, aromatherapy, ear seed therapy, and gentle movement, have excellent outcomes and benefits on their own. (debrareis.com)
  • We believe that holistic physical therapy is the key to healing. (neurofeedbackiti.com)
  • Mirada RTx is integrated into Vitrea™ Advanced Visualization and provides software tools for radiation therapy treatment planning that brings new levels of functionality, speed and accuracy to the planning process. (medical.canon)
  • Cold Therapy passes cool fluid through the wrap for the management of pain, discomfort and swelling. (metromedicalus.com)
  • Heat Therapy passes 105 degree F fluid through the wrap for the management of pain and discomfort. (metromedicalus.com)
  • Thermal Contrast Therapy passes fluid through the wrap in an alternating cycle of Cool-Heat-Cool-Heat for the management of pain, discomfort and swelling. (metromedicalus.com)
  • Ear Seed Therapy - can be used for specific concerns such as nausea, discomfort, and stress. (debrareis.com)
  • Many supportive therapies have reduced treatment side effects such as nausea, mood changes, and discomfort. (debrareis.com)
  • If a cure cannot be obtained, palliative therapy is given to treat pain and discomfort. (cdc.gov)
  • Cell therapists need to follow stem cells for weeks, months, and even years after they are introduced as therapy, according to Gambhir. (diagnosticimaging.com)
  • In schema therapy, therapists work to help those in therapy create messages designed for the caregivers who failed to meet their childhood emotional needs. (goodtherapy.org)
  • Our approach to therapy is truly state-of-the-art, and we provide the finest in therapists, equipment and services. (timberlinehealth.com)
  • The therapy staff is part of the "bricks and mortar" of The Oaks at Timberline, and our therapists take pride in the performance of the therapy department as well as the entire facility. (timberlinehealth.com)
  • Our therapists receive education and training to other disciplines, to ensure the continuity of care between therapy and nursing. (timberlinehealth.com)
  • Our therapy staff are dedicated full-time employees, so guests can rely on getting to know the same caring therapists for the duration of their stay. (rockcanyonrehab.com)
  • As part of the Rock Canyon team, our therapists receive education and training to ensure a solid continuity between therapy and nursing care. (rockcanyonrehab.com)
  • Molecular imaging is playing a central role in shaping the future of cell-based therapies. (diagnosticimaging.com)
  • 2021). 'Study of the Enhanced Role of Latanoprost Combined with Narrow Band Ultraviolet B Rays in Vitiligo Repigmentation', European Journal of Molecular & Clinical Medicine , 8(3), pp. 3423-3433. (ejmcm.com)
  • By matching these two data sets in a meaningful way, we can better tailor individualized therapy programs to the patient's unique needs. (timberlinehealth.com)
  • Candela Profound Matrix system combines three unique modalities of radiofrequency to correct, maintain and restore a patient's skin across the aging journey. (medestheticsmag.com)
  • This therapy involves evaluation to assess the patient's posture, flexibility, pain, and the health history. (neurofeedbackiti.com)
  • Photodynamic therapy (PDT) is a treatment modality for small confined light-accessible tumors. (univ-lorraine.fr)
  • Radiation oncology, also referred to as radiation therapy, uses ionizing radiation in the treatment of cancerous and non-cancerous or benign tumors. (northside.com)
  • We have enhanced our COVID-19 vaccine leadership and reported encouraging data for our first-in-human CAR-T therapy in solid tumors. (gcs-web.com)
  • But there was a question of how to approach movement as regenerative therapy. (movnat.com)
  • Nationwide, there has been a notable decrease in combined modality therapy, especially in clinical trials, many of which are designed to avoid this strategy," explained Parikh. (medpagetoday.com)
  • Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used. (jefferson.edu)
  • And that's used in many combinations in Waldenstrom's and is a very important therapy currently. (powerfulpatients.org)
  • Although MRI, PET, and optical imaging are all used to track stem cells, the underlying imaging strategy, regardless of modality, is based on the nuclear medicine tracer principle discovered by George de Hevesy. (diagnosticimaging.com)
  • To help remedy the lack of job opportunities, a 2013 survey of nuclear medicine residency program managers advocated combining nuclear medicine residency programs with radiology to give graduates dual certification from ABR and ABNM. (auntminnie.com)
  • Hodgkin lymphoma is considered to be a curable malignancy, but therapies for this disease can have significant long-term toxicity. (medscape.com)
  • Tumor size, lymph node involvement, and grade are anatomical prognostic factors, while estrogen receptor, progesterone receptor, and HER2 status are predictive of response to therapy. (cancer.gov)
  • T3 binds to the nuclear receptor (TR) and combines with another receptor (RXR) then combines with a receptor element on DNA. (cdc.gov)
  • Mirada Oncology Fusion is an integrated multiple modality software application for the evaluation of oncologic disease. (medical.canon)
  • obesity will need alignment of the intensity of therapy with the severity of disease and integration of therapy with Sumner M Redstone Global environmental changes that reinforce clinical strategies. (bvs.br)
  • Ninety-four percent overall survival at 8 years for the lumpectomy alone group, while the combined modality arm had a 95% 8 year overall survival. (oncolink.org)
  • Musculoskeletal therapy deals with the connection between the muscles, joints, the skeleton, and how these body parts work together to keep optimal health and wellness. (neurofeedbackiti.com)
  • The Hippocrates Health Institute is the premiere wellness institute in the world and similarly is recognized world-wide, where our guests travel from all parts for the globe to learn and benefit from all the modalities that we have provided. (ideamensch.com)
  • Integrating two therapies, Theraplay and EMDR therapy, can have a synergistic effect of facilitating healing in these children. (theraplay.org)
  • And then the medical oncologist provides the systemic therapy or recommendation. (curetoday.com)
  • Nonetheless, further research is needed to develop therapies that would optimize outcomes and reduce morbidity, as would studies of treatment mechanisms, mediators, and moderators of outcomes. (nih.gov)
  • Continuous combined hormonal contraceptives decrease recurrent dysmenorrhea for up to 24 months after surgery. (exxcellence.org)
  • Progestin therapy such as norethindrone acetate, depo medroxyprogesterone acetate (DMPA), and the levonorgestrel releasing intrauterine system (LNG-IUS) have all been shown to decrease pain recurrence rates. (exxcellence.org)
  • After 1 month of low-dose interferon maintenance therapy, the bilateral inguinal lymph nodes developed metastases. (spandidos-publications.com)
  • Hysterectomy and bilateral oophorectomy alone is inadequate for definitive therapy if endometriosis involving the bowel is left untreated. (exxcellence.org)
  • Definitive surgical therapy (hysterectomy with or without bilateral oophorectomy), should be reserved for women with severe symptoms who have completed childbearing. (exxcellence.org)
  • Recent studies, however, are finding acupuncture to be an efficacious treatment option, particularly when combined with conventional methods. (ispub.com)
  • Participants will learn when and how to best integrate these two treatment models in play therapy sessions in order to give voice to both the right and left brain. (theraplay.org)
  • Learn how to combine the Soul Lightening Acupressure Chest Release for Self-Care with Qigong movement practices, to support and enhance pulmonary health in preparation for the winter season. (reginarosenthal.com)
  • EMDR- Click here to learn more about this effective therapy, which can help you to process and clear stuck emotions around triggers and painful experiences. (creativejourneyscounseling.com)
  • Comprehensive Resource Model- Click here to learn more about this compassionate and proundly deep modality. (creativejourneyscounseling.com)
  • The 1-day conference was divided into 3 sessions: (1) pretreatment assessment, (2) surgical treatment, and (3) combined modality treatment. (medscape.com)
  • Effectiveness studies are also needed to validate those therapies when implemented in clinical settings (primary care), by non-sleep specialists. (nih.gov)
  • This review further evaluates the hypothesis that the effectiveness of gemcitabine can be improved by combining it with evidence-based complementary measures. (lse.ac.uk)
  • However, it is clear that although 18 F-FDG is the mainstay for PET, it is not suited for all applications and, in particular, for monitoring the effectiveness of highly specialized therapies. (snmjournals.org)
  • Clinical studies have long studied the effectiveness of light therapy on mood and Seasonal Effective Disorder. (articlecity.com)
  • For best treatment results, radiation therapy treatment may be used alone or combined with other modalities, such as chemotherapy or surgery. (northside.com)