Combined Modality Therapy
Mechlorethamine
Procarbazine
Hodgkin Disease
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
Antineoplastic Combined Chemotherapy Protocols
Prednisone
Actuarial Analysis
The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.
Carcinoma, Small Cell
Radiotherapy, Adjuvant
Neoplasm Staging
Cyclophosphamide
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Survival Analysis
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Doxorubicin
Prognosis
Cisplatin
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Chemotherapy, Adjuvant
Treatment Outcome
Clinical Trials as Topic
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Survival Rate
Disease-Free Survival
Fluorouracil
Carcinoma, Non-Small-Cell Lung
Follow-Up Studies
Diagnostic Imaging
Magnetic Resonance Imaging
Tomography, X-Ray Computed
Neoadjuvant Therapy
PubMed
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Taxoids
Head and Neck Neoplasms
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Induction Chemotherapy
Systems Biology
Adenoviral gene transfer into the normal and injured spinal cord: enhanced transgene stability by combined administration of temperature-sensitive virus and transient immune blockade. (1/14907)
This study characterized gene transfer into both normal and injured adult rat dorsal spinal cord using first (E1-/E3-) or second (E1-/E2A125/E3-, temperature-sensitive; ts) generation of replication-defective adenoviral (Ad) vectors. A novel immunosuppressive regimen aimed at blocking CD4/CD45 lymphocytic receptors was tested for improving transgene persistence. In addition, the effect of gene transfer on nociception was also evaluated. Seven days after treatment, numerous LacZ-positive cells were observed after transfection with either viral vector. By 21 days after transfection, beta-galactosidase staining was reduced and suggestive of ongoing cytopathology in both Ad-treated groups, despite the fact that the immunogenicity of LacZ/Adts appeared less when compared with that elicited by the LacZ/Ad vector. In contrast, immunosuppressed animals showed a significant (P < or = 0.05) increase in the number of LacZ-positive cells not displaying cytopathology. In these animals, a concomitant reduction in numbers of macrophages/microglia and CD4 and CD8 lymphocytes was observed. Only animals that received LacZ/Adts and immunosuppression showed transgene expression after 60 days. Similar results were observed in animals in which the L4-L5 dorsal roots were lesioned before transfection. Gene transfer into the dorsal spinal cord did not affect nociception, independent of the adenovirus vector. These results indicate that immune blockade of the CD4/CD45 lymphocytic receptors enhanced transgene stability in adult animals with normal or injured spinal cords and that persistent transgene expression in the spinal cord does not interfere with normal neural function. (+info)Systemic administration of rIL-12 synergistically enhances the therapeutic effect of a TNF gene-transduced cancer vaccine. (2/14907)
Interleukin-12 (IL-12) is a potent antitumor cytokine, which induces and enhances the activity of natural killer (NK) cells, lymphokine activated killer (LAK) cells and cytotoxic T lymphocytes (CTL). IL-12 also stimulates IFN-gamma production from both T cells and NK cells. In this study, we transfected methylcholanthrene-induced fibrosarcoma (MCA-D) with TNF gene and investigated the therapeutic effect of TNF gene-transduced cancer vaccine and whether the vaccination effect is enhanced by systemic administration of recombinant IL-12 (rIL-12), in a murine model. TNF gene-transduced cancer vaccine or systemic administration of rIL-12 showed slight or moderate inhibition of pre-established tumor. However, simultaneous application of the vaccine and rIL-12 resulted in complete eradication. The cytotoxicity of CTL against parental tumor cells was enhanced with the combination of the vaccine and rIL-12, and IFN-gamma production from spleen cells also increased synergistically. Our findings show that synergistic enhancement of CTL activity and IFN-gamma production could play an important role in the antitumor effect of combination therapy using TNF gene-transduced cancer vaccine and rIL-12. (+info)Reirradiation combined with hyperthermia in recurrent breast cancer results in a worthwhile local palliation. (3/14907)
Both experimental and clinical research have shown that hyperthermia (HT) gives valuable additional effects when applied in combination with radiotherapy (RT). The purpose of this study was evaluation of results in patients with recurrent breast cancer, treated at the Daniel den Hoed Cancer Center (DHCC) with reirradiation (re-RT; eight fractions of 4 Gy twice weekly) combined with HT. All 134 patients for whom such treatment was planned were included in the analysis. The complete response rate in 119 patients with macroscopic tumour was 71%. Including the 15 patients with microscopic disease, the local control rate was 73%. The median duration of local control was 32 months, and toxicity was acceptable. The complete response (CR) rate was higher, and the toxicity was less with the later developed 433-MHz HT technique compared with the 2450-MHz technique used initially. With this relatively well-tolerated treatment, palliation by local tumour control of a worthwhile duration is achieved in the majority of patients. The technique used for hyperthermia appeared to influence the achieved results. The value of HT in addition to this re-RT schedule has been confirmed by a prospective randomized trial in a similar patient group. In The Netherlands, this combined treatment is offered as standard to patients with breast cancer recurring in previously irradiated areas. (+info)A prospective randomized study of megestrol acetate and ibuprofen in gastrointestinal cancer patients with weight loss. (4/14907)
The use of megestrol acetate in the treatment of weight loss in gastrointestinal cancer patients has been disappointing. The aim of the present study was to compare the combination of megestrol acetate and placebo with megestrol acetate and ibuprofen in the treatment of weight loss in such patients. At baseline, 4-6 weeks and 12 weeks, patients underwent measurements of anthropometry, concentrations of albumin and C-reactive protein and assessment of appetite, performance status and quality of life using EuroQol-EQ-5D and EORTC QLQ-C30. Thirty-eight and 35 patients (median weight loss 18%) were randomized to megestrol acetate/placebo or megestrol acetate/ibuprofen, respectively, for 12 weeks. Forty-six (63%) of patients failed to complete the 12-week assessment. Of those evaluable at 12 weeks, there was a decrease in weight (median 2.8 kg) in the megestrol acetate/placebo group compared with an increase (median 2.3 kg) in the megestrol acetate/ibuprofen group (P<0.001). There was also an improvement in the EuroQol-EQ-5D quality of life scores of the latter group (P<0.05). The combination of megestrol acetate/ibuprofen appeared to reverse weight loss and appeared to improve quality of life in patients with advanced gastrointestinal cancer. Further trials of this novel regimen in weight-losing patients with hormone-insensitive cancers are warranted. (+info)The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cell recipients. (5/14907)
We analysed 57 patients with non-myeloid malignancies who received a non-purged autologous PBSCT. All had similar mobilisation and conditioning regimens. A high prior chemotherapy score and the number of chemotherapy lines used (P = 0.015 and P = 0.01, respectively) were adverse predictors of CD34 cell yields. Lower CD34 values (P = 0.002) were seen in patients treated with potent stem cell toxins (BCNU, melphalan, CCNU and mustine), designated toxicity factor 4 agents (TF4). All patients infused with grafts containing CD34 cell doses between 1.0 and 2.0 x 10(6)/kg (range 1.25-1.90) engrafted by day 51. The only variable associated with slow platelet recovery was exposure to TF4 (P = 0.007). The majority of patients with CD34 >1.0 x 10(6)/kg achieved rapid and sustained engraftment and the only predictive factor of delayed recovery is prior exposure to stem cell toxins. Potential PBSCT candidates should if possible avoid first line and salvage chemotherapy containing TF4 drugs. We therefore advocate a minimum CD34 threshold of >1.0 x 10(6)/kg in patients without extensive prior chemoradiotherapy, and > or = 2.0 x 10(6)/kg in all other patients. (+info)Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. (6/14907)
The effect of an extensive prophylactic antimicrobial regimen was prospectively assessed in 126 patients after high-dose chemotherapy and autologous PBSC. They received ciprofloxacin (500 mg/12 h), acyclovir (200 mg/6 h), and itraconazole (200 mg/12 h) orally until neutrophil recovery. Febrile patients received i.v. imipenem (500 mg/6 h) to which vancomycin and amikacin were added if fever persisted for 2-3 and 5 days, respectively. Amphotericin B lipid complex was further given on day 7 or 8 of fever. Median times for a neutrophil count of >0.5 x 10(9)/l and a platelet count of >20 x 10(9)/l were 9 and 11 days. Severe neutropenia (<0.1 x 10(9)/l) lasted for a median of 5 days in which 72% of febrile episodes and 50% of cases of bacteremia occurred. Gram-positive bacteria were isolated in 30 of 40 episodes of bacteremia, 25 of which were caused by Staphylococcus epidermidis. Clinical foci were the intravascular catheter in 35 cases, respiratory infection in 11, cellulitis in two, anal abscess in one, and neutropenic enterocolitis in one. The high incidence of febrile episodes (94%) and bacteremias (31%) may be due to the lack of efficacy of antimicrobial prophylaxis and the persistence of a 5-day period of severe neutropenia. (+info)Lymphomatoid granulomatosis following autologous stem cell transplantation. (7/14907)
Lymphomatoid granulomatosis (LYG) is a rare angio-destructive lymphoproliferative disorder (LPD) of uncertain etiology, with prominent pulmonary involvement. Recent studies indicate that LYG is an Epstein-Barr virus (EBV)-associated B cell LPD with large numbers of background reactive T lymphocytes (T cell-rich B cell lymphoma). Although the disease frequently, but not exclusively, occurs in various immunodeficiency states, it has not been reported in association with the transient immunosuppression following autologous bone marrow/peripheral stem cell transplantation (ABM/PSCT). We describe a patient who developed lymphomatoid granulomatosis of the lung approximately 2 weeks after high-dose chemotherapy and autologous peripheral stem cell transplantation for multiple myeloma. Although molecular studies showed no evidence of EBV genome in the biopsy material, the serologic profile with high IgM titers was suggestive of primary EBV infection. Complete radiologic remission occurred following reconstitution of the patient's immune response after a 2-week course of ganciclovir treatment. Despite the apparently low frequency of LPD (both LYG and EBV-associated post-transplant lymphoma) in the ABMT setting, we believe that it should be considered in the differential diagnosis of patients whose clinical course following ABMT is complicated by fevers, in the absence of an identifiable infectious process. (+info)Phase I study of eniluracil, a dihydropyrimidine dehydrogenase inactivator, and oral 5-fluorouracil with radiation therapy in patients with recurrent or advanced head and neck cancer. (8/14907)
5-Fluorouracil (5-FU) is an effective enhancer of radiation therapy (RT) in head and neck cancers. Due to rapid, predominantly hepatic metabolism by dihydropyrimidine dehydrogenase (DPD) and suggested clinical benefit from prolonged drug exposure, 5-FU is commonly given by continuous infusion. Eniluracil is a novel DPD-inactivator designed to prolong the half-life of 5-FU and provide sustained plasma concentrations of 5-FU with oral dosing. We conducted a Phase I study of the safety and efficacy of eniluracil given with oral 5-FU in patients receiving concurrent RT for recurrent or advanced squamous cell carcinomas of the head and neck. Thirteen patients with recurrent, metastatic, or high-risk (defined as an expected 2-year survival rate of <10%) head and neck cancer were enrolled and treated with concomitant chemoradiotherapy on an every-other-week schedule. Eniluracil at a fixed dose [20 mg twice a day (BID)] was given for 7 consecutive days (days 1-7). 5-FU and RT were given on 5 consecutive days (days 2-6). One patient was treated with once-daily RT (2.0 Gy fractions). The remaining patients received hyperfractionated RT (1.5-Gy fractions BID). The initial dose of 5-FU was 2.5 mg/m2 given BID. Dose escalation in patient cohorts was scheduled at 2.5-mg/m2 increments, with intrapatient dose escalation permitted. Lymphocyte DPD activity and serum 5-FU and uracil concentrations were monitored during two cycles. DPD activity was completely or nearly completely inactivated in all patients. Sustained, presumed therapeutic concentrations of 5-FU were observed at a dose of 5.0 mg/m2 given BID. Cumulative dose-limiting myelosuppression (both neutropenia and thrombocytopenia) was observed during the fourth and fifth cycles following administration of 5.0 mg/m2 5-FU BID. One patient died of neutropenic sepsis during cycle 4. Other late cycle toxicities included diarrhea, fatigue, and mucositis. Grade 3 mucositis was observed in 4 patients, but no grade 4 mucositis or grade 3 or 4 dermatitis was observed. A second patient death occurred during cycle 1 of treatment. No specific cause of death was identified. The study was subsequently discontinued. Cumulative myelosupression was the significant dose-limiting toxicity of oral 5-FU given with the DPD-inactivator eniluracil on an every-other-week schedule. Clinical radiation sensitization was not observed, based on the absence of dose-limiting mucositis and dermatitis. Alternative dosing schedules need to be examined to determine the most appropriate use of eniluracil and 5-FU as radiation enhancers. (+info)
Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced...
Cureus | Abscopal Effect, From Myth to Reality: From Radiation Oncologists Perspective
Long-term follow-up of the RTOG 9501/intergroup phase III trial: Postoperative concurrent radiation therapy and chemotherapy in...
Commentary (Kleinberg et al): Primary Combined-Modality Therapy for Esophageal Cancer
Concurrent Chemoradiation Therapy is Viable Strategy for Bladder Cancer - The ASCO Post
Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4...
Chemotherapy plus radiotherapy shown to lower risk of recurrence after surgery · Pancreatic Cancer Action
The Use of Chemotherapy Plus Radiotherapy Plus Azidothymidine in Patients With AIDS-Related Lymph Node Cancer - Full Text View ...
The Use of Chemotherapy Plus Radiotherapy Plus Azidothymidine in Patients With AIDS-Related Lymph Node Cancer - Full Text View ...
Abscopal Effect: Definition and Role in Cancer Treatment
Generating and grading the abscopal effect: proposal for comprehensive evaluation of combination immunoradiotherapy in mouse...
Generating and grading the abscopal effect: proposal for comprehensive evaluation of combination immunoradiotherapy in mouse...
Radiation plus chemotherapy doesnt improve endometrial cancer recurrence-free survival
Multidisciplinary Management of Colorectal Cancer Enhances Perioperative Evaluation and Access to Multimodal Therapy - SAGES...
Docetaxel and Radiation as Combined-Modality Therapy | Cancer Network | The Oncology Journal
Radiation Plus Hormone Therapy Cuts Prostate Can... ( Study confirms effectiveness of widel...)
THE MULTIMODAL THERAPY OF ADHD WITH COMORBIDITIES - SNPCAR
Andre A Konski | Faculty | About Us | Perelman School of Medicine | Perelman School of Medicine at the University of...
DeVita, Hellman, and Rosenbergs Cancer: Principles & Practice of Oncology
Modeling T-Cell Trafficking to Increase the Likelihood of Radiation-Induced Abscopal Effects
Search
Vorinostat Plus Radiation Therapy in Pancreatic Cancer
Advances in Treatment Planning Systems | Imaging Technology News
2018 - OncoRad - NBXTR3 Abscopal Effect<...
Salvage concurrent radio-chemotherapy for post-operative local recurrence of squamous-cell esophageal cancer | Radiation...
Adjuvant therapy in colorectal cancer. A randomized trial comparing radio-chemotherapy and radio-chemotherapy combined with...
Plus it
From conventionally fractionated radiation therapy to hyperfractionated radiation therapy alone and with concurrent...
Rare Cancer News & Clinical Trials » Trial - Sarcoma » A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced...
Omitting radiotherapy in early positron emission tomography-negative stage I/II Hodgkin lymphoma is associated with an...
Comparison of 30 Gy versus 20 Gy Involved Field Radiotherapy After Two Versus Four Cycles ABVD in Early Stage Hodgkins...
PWE-326 Extending the scope of tem - effect of radiotherapy on outcome in locally excised t2 rectal cancer | Gut
Dr. Schoenfeld on Low-Dose Radiation Plus Immunotherapy in Head and Neck Cancer
Postoperative radiation therapy in the management of head and neck cancer
PRIME PubMed | [Combined-modality therapy for 150 cases of early-stage Hodgkins lymphoma
The value of metabolic imaging to predict tumour response after chemoradiation in locally advanced rectal cancer | Radiation...
GOG 0238: A Randomized Trial of Pelvic Irradiation with or without Concurrent Weekly Cisplatin in Patients with Pelvic-only...
Rare Medical Phenomenon Of Systemic Tumor Disappearance Following Local Radiation Treatment Reported In A Patient With...
Combined Modality Therapy of Childhood Non-Hodgkins Lymphoma | Springer for Research & Development
trial data
A Phase I Clinical Trial Assessing Temozolamide and Tamoxifen with Concomitant Radiotherapy for the Treatment of High-Grade...
Efficacy of Once- vs Twice-daily Ratiotherapy for SCLC With Concurrent Chemoradiotherapy
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage | PNAS
Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. - PubMed - NCBI
Potential Molecular Targets in the Setting of Chemoradiation for Esophageal Malignancies<...
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer
Search Clinical Trials | Froedtert & MCW
Search Clinical Trials | Froedtert & MCW
Project MUSE - Living with Lymphoma
Biochemical Control in Acromegaly With Multimodality Therapy
Articles, Interviews and Websites for Alternative Cancer Information ⁄ Cancer Compass~An Alternate Route
Article - A multimodality approach to oncologic imaging
IJMS | Free Full-Text | Biomarkers of Treatment Toxicity in Combined-Modality Cancer Therapies with Radiation and Systemic...
combined modality therapy
What are the side effects of high-dose chemotherapy for cancer? | Chemotherapy For Cancer - Sharecare
Treatment and survival - VCU Massey Cancer Center
Application of Radiotherapy and Chemotherapy Protocols to Pre‐Clinical Tumor Models - Current Protocols
Short-Term ADT Plus RT for Prostate Cancer Boosts Survival - Renal and Urology News
Pricing - Adam and Eve Day Spa
Dolore perineale worth texas ** Amenorrea e dolore pelvico
Modalities / Healing Agents
Michael L. J. Apuzzo
Combined Modality Therapy of Central Nervous System Tumors. ISBN 9783540006275. Hoh DJ, Liu CY, Pagnini PG, Yu C, Wang MY, ... Chained lightning: part III--Emerging technology, novel therapeutic strategies, and new energy modalities for radiosurgery. ... technology transfer and the implementation of advanced technologies to the therapy of brain diseases. In 1991, he was appointed ...
Precocious puberty
"Intracranial choriocarcinoma causing precocious puberty and cured with combined modality therapy". Journal of Paediatrics and ...
Total body irradiation
December 1983). "Intensive combined modality therapy including low-dose TBI in high-risk Ewing's Sarcoma Patients". Int. J. ... In addition to its use in bone marrow transplantation, total body irradiation has been explored as a treatment modality for ... August 2003). "High-dose therapy for patients with primary multifocal and early relapsed Ewing's tumors: results of two ...
Manual lymphatic drainage
"Manual Lymph Drainage Combined With Compression Therapy for Arm Lymph- edema Following Breast Cancer Treatment" (PDF). Swedish ... Stillerman, Elaine (2009). Modalities for Massage and Bodywork. Mosby. pp. 129-143. ISBN 032305255X. " ... Explanation of Manual lymphedema therapy on the National Cancer Institute web site.. ... they returned to Copenhagen to teach other practitioners to use this therapy. Milady's Guide to Lymph Drainage Massage; Ramona ...
Joaquín Gómez Mira
Mira, J.G.: Combined Modality Treatment for Small Cell Lung Cancer. Chapter in Combined Chemotherapy and Radiotherapy in ... He was elected Head of the Radiotherapy department of the Cancer Therapy & Research Center every year between 1993 and 2007. He ... He was named Director of Radiotherapy in the Cancer Therapy & Research Center, under the National Cancer Institute, where he ... McCracken, J.D. and Mira, J.G.: Concurrent Chemotherapy and Radiation Therapy for Limited Small Cell Lung Cancer. Monograph, ...
Primary immunodeficiency
VST therapy uses active donor T-cells that are isolated from alloreactive T-cells which have proven immunity against one or ... The main members are various types of severe combined immunodeficiency (SCID). T-/B+ SCID (T cells predominantly absent): γc ... Most treatment is therefore passive and palliative, and falls into two modalities: managing infections and boosting the immune ... T-lymphocyte therapies are still in the experimental stage; few are even in clinical trials, none have been FDA approved, and ...
Polyestradiol phosphate
Transgender hormone therapy (male-to-female). *Estradiol-containing birth control pill. *Combined injectable birth control ... there was no difference in survival or cardiovascular toxicity between the two treatment modalities.[21][22] These findings ... It is also used in feminizing hormone therapy for transgender women.[11][19] PEP is a form of high-dose estrogen therapy.[2] ... PEP is used as an intramuscular injection for estrogen therapy of prostate cancer in men.[1][2] It is also used to treat breast ...
Treatment of lung cancer
It is possible that the two modalities have a synergistic effect and patients may benefit from combined treatment. Prior to the ... An animal tumor model demonstrated improved survival after combined treatment with RFA and radiation therapy compared to either ... Reduced tumor growth with combined radiofrequency ablation and radiation therapy in a rat breast tumor model. Radiology 2005. ... July 2006). "Percutaneous Image-guided Thermal Ablation and Radiation Therapy: Outcomes of Combined Treatment for 41 Patients ...
Holistic nursing
These therapy modalities are focused on empowering individuals to reduce stress levels and elicit a relaxation response in ... Holistic nursing combines standard nursing interventions with various modalities that are focused on treating the patient in ... Alternative therapies can include stress management, aroma therapy, and therapeutic touch. The combination of interventions ... Several of the therapies included in holistic nursing rely on therapeutic environments to be successful and effective. A ...
Cancer research
... hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the ... is a prostate cancer vaccine Newer forms of chemotherapy Gene therapy Photodynamic therapy Radiation therapy Reoviridae ( ... Reolysin drug therapy) Targeted therapy Natural killer cells can induce immunological memory. Research is being developed to ... Radiation therapy took hold in the 1900s. Chemotherapeutics were developed and refined throughout the 20th century. The U.S. ...
Psychomotor patterning
The therapy normally lasts for 5 minutes and is repeated at least 4 times a day. Full treatment programs typically contain a ... The treatment modality of patterning was developed in the 1960s by Glenn Doman and Carl Delacato. The Institutes for the ... range of exercises combined with sensory stimulation, breathing exercises designed to increase oxygen flow to the brain, and ... and treatment primarily focuses on non-invasive physical therapy in each of these stages. In one such stage, the homolateral ...
Rak żołądka człowieka, wolna encyklopedia
... quality of combined modality therapy and pathologic response. „J Clin Oncol". 24 (24), s. 3953-3958, Aug 2006. DOI: 10.1200/JCO ... Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5- ... a b c d e f M. Kaminishi, K. Takubo, K. Mafune: The Diversity of Gastric Carcinoma: Pathogenesis, Diagnosis and Therapy. ... Cancer Therapy", 2007. [zarchiwizowane z adresu]. *↑ W.H. Chow, W.J. Blot, T.L. Vaughan, H.A. Risch i inni. Body mass index and ...
Anal cancer
The best overall survival rates are seen after combined radiation therapy combined with chemotherapy (5-FU + Mitomycin) in ... This "combined modality" approach has led to the increased preservation of an intact anal sphincter, and therefore improved ... Current gold-standard therapy is chemotherapy and radiation treatment to reduce the necessity of debilitating surgery. ... Standard treatment may include radiation therapy, chemotherapy, and surgery. About 8,300 people are diagnosed a year in the ...
Radiation oncologist
... and combined modality therapy such as radiotherapy with surgery, chemotherapy, or immunotherapy. To provide the treatment ... Radiation can be given as a curative modality, either alone or in combination with surgery and/or chemotherapy. It may also be ... Radiotherapy training in India encompasses the treatment of solid tumors in terms of Chemotherapy, radiation therapy, and ... In Iran, radiation oncologists, who are trained in non-surgical aspects of oncology (including radiation therapy) directly ...
Telerehabilitation
... is therefore often combined with other modalities such as in-person therapy. Important areas of ... Types of therapy available include motor training exercises, speech therapy, virtual reality, robotic therapy, goal setting, ... robotic therapy, and community-therapy. Motor training exercises are the most commonly implemented modality. In motor training ... Robotic therapy has even been combined with virtual reality telerehabilitation to create a virtual environment which responds ...
Minesh Mehta
... combined modality therapies, altered fractionation, cost-effectiveness, and outcomes research. He has run numerous ... Combined modality treatment of tumors of the CNS and thorax, as well as pediatric neoplasms: integrating systemic chemotherapy ... Effects of therapies on cognition and developing methods to improve neurocognitive function. Medical director, the Maryland ... Chair, Brain Tumor Committee, Radiation Therapy Oncology Group. "Faculty Profiles: University of Maryland School of Medicine". ...
Management of prostate cancer
Others use a "triple modality" combination of external beam radiation therapy, brachytherapy, and hormonal therapy. In advanced ... when surgery or radiation therapy alone is less likely to cure the cancer. Some radiation oncologists combine external beam ... and photodynamic therapy that permit focal therapy by utilizing image guidance. These therapies are still in beginning or ... and external-beam radiation therapy, proton therapy, high-intensity focused ultrasound (HIFU), cryosurgery, hormonal therapy, ...
Art therapy
... and play therapists combine art therapy methods with basic psychotherapeutic modalities in their treatment. Therapists may ... Art therapy (not to be confused with arts therapy which includes other creative therapies such as drama therapy and music ... Art therapy, as a creative arts therapy modality, originated in the fields of art and psychotherapy and may vary in definition ... Chambala, A (2008). "Anxiety and art therapy: Treatment in the public eye". Art Therapy: Journal of the American Art Therapy ...
Psychotherapy
This includes the modalities dance therapy, drama therapy, art therapy, music therapy, writing therapy, among others. This may ... meseron therapy and systemic therapies based on the Ubuntu philosophy. Integrative psychotherapy is an attempt to combine ideas ... multimodal therapy, and therapies for specific disorders including PTSD therapies such as cognitive processing therapy and EMDR ... including couples therapy and family therapy. Therapies are sometimes classified according to their duration; a small number of ...
Medically unexplained physical symptoms
A combined therapeutic approach which is at least twice as effective as other therapeutic modalities published to date is ... Jackson JL, O'Malley PG, Kroenke K (March 2006). "Antidepressants and cognitive-behavioral therapy for symptom syndromes". CNS ... Steele RE, de Leeuw E, Carpenter D. "A novel and effective treatment modality for medically unexplained symptoms" J Pain ... O'Malley, PG; Jackson, JL; Santoro, J; Tomkins, G; Balden, E; Kroenke, K (December 1999). "Antidepressant therapy for ...
Carcinoid
Surgery, if feasible, is the only curative therapy. If the tumor has metastasized (most commonly, to the liver) and is ... Interferon treatment is also effective, and usually combined with somatostatin analogues.. As the metastatic potential of a ... considered incurable, there are some promising treatment modalities, such as radiolabeled octreotide [5] (e.g. Lutetium (177Lu ...
Osteoradionecrosis
Ultrasound therapy: First introduced as a treatment modality in 1992, it involves the application of high-frequency sound waves ... Multidisciplinary approach (HBO + Surgery): Studies have shown support of combining HBO therapy and a surgical approach to ... while combined with debridement. Hyperbaric oxygen therapy (HBO): First described in 1973, HBO was intended to be an adjunctive ... which is likely attributable to improvements in radiation therapy. Radiation therapy destroys cancer primarily by causing DNA ...
Psychotherapy
This includes the modalities dance therapy, drama therapy, art therapy, music therapy, writing therapy, among others. ... Cognitive behavioral therapy attempts to combine the above two approaches, focused on the construction and reconstruction of ... multimodal therapy, and therapies for specific disorders including PTSD therapies such as cognitive processing therapy and EMDR ... In African countries this includes harmony restoration therapy, meseron therapy and systemic therapies based on the Ubuntu ...
Chemoimmunotherapy
It is clear that strategically integrating immune-based therapies with standard cancer treatment modalities, in particular ... Chemoimmunotherapy is chemotherapy combined with immunotherapy. Chemotherapy uses different drugs to kill or slow the growth of ... whereas systemic therapies (chemotherapy, endocrine therapy, molecularly targeted therapies, and adjunctive therapies ( ... Combination of different therapies in cancer has become a trend, not just between different types of therapies, also multiple ...
Trichophyton rubrum
Current treatment modalities include oral terbinafine, oral itraconazole, and intermittent "pulse therapy" with oral ... Topical treatment by occlusive dressing combining 20% urea paste with 2% tolnaftate have also shown promise in softening the ... Gupta, AK; Daigle, D; Paquet, M (17 July 2014). "Therapies for Onychomycosis: A Systematic Review and Network Meta-Analysis of ... These infections are usually unresponsive to topical treatments and respond only to systemic therapy. Although it is most ...
Anaplastic thyroid cancer
Palliative treatment consists of radiation therapy usually combined with chemotherapy. The use of tracheostomy as part of ... and if combined modality treatment is used. Treatment of anaplastic thyroid cancer is generally palliative in its intent due to ... Combinatorial therapy that is molecular-based may lead to significant tumor regression, potentially making patients amenable to ... Recent advances show that using a combination of novel targeted therapies, immunotherapy, and surgery, 1 year and 2 year ...
Bibliotherapy
... poetry therapy or therapeutic storytelling) is a creative arts therapies modality that involves storytelling or the reading of ... Bibliotherapy is often combined with writing therapy. It has been shown to be effective in the treatment of depression. A 3 ... The United Kingdom, beginning in the 1930s, also began to show growth in the use in of reading therapy in hospital libraries. ... Clarke, J.M. (1984). "Reading therapy - an outline of its growth in the UK". In Jean M. Clarke; Eileen Bostle (eds.). Reading ...
Prostvac
... to evaluate the potential clinical benefit of combining PROSTVAC with different treatment modalities such as hormonal therapies ... Based on non-clinical data supporting the scientific rationale for combination therapy with PROSTVAC, additional clinical ...
Alternative medicine
Examples include immuno-augmentation therapy, shark cartilage, bioresonance therapy, oxygen and ozone therapies, and insulin ... since there is a growing body of research on some of these modalities, and some aspects of standard care do not have a strong ... of extravagant claims by the alternative medical community combined with inadequate media scrutiny and attacks on critics.[122] ... Prevalence of use of specific therapies. The most common CAM therapies used in the US in 2002 were prayer (45%), herbalism (19 ...
Positron emission tomography
PET has an expanding role as a method to assess the response to therapy, in particular, cancer therapy,[57] where the risk to ... April 2005). "Radiation exposure of patients undergoing whole-body dual-modality 18F-FDG PET/CT examinations". J. Nucl. Med. 46 ... combined with a positron emission tomograph (PET). Presently, only the head and brain can be imaged at these high magnetic ... Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy. Boca Raton: CRC Press. pp. 156-159.. ...
Acne
Hormonal treatments for acne such as combined birth control pills and antiandrogens may be considered a first-line therapy for ... PDT has the most supporting evidence of all light therapy modalities.[77] ... Combination therapy[edit]. Combination therapy-using medications of different classes together, each with a different mechanism ... The evidence for light therapy as a treatment for acne is weak and inconclusive.[8][155] Various light therapies appear to ...
Chiropractic
... and other manual therapies to the joints and soft tissues, rehabilitative exercises, health promotion, electrical modalities, ... "Combined chiropractic interventions for low-back pain". Cochrane Database of Systematic Reviews (4): CD005427. doi:10.1002/ ... Chiropractic overlaps with several other forms of manual therapy, including massage therapy, osteopathy, physical therapy, and ... The main chiropractic treatment technique involves manual therapy, especially spinal manipulation therapy (SMT), manipulations ...
Antiandrogen
Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy. World Health Organization. ... therapeutic modalities that reduce androgen signaling in the prostate gland, referred to collectively as androgen deprivation ... Katsambas AD, Dessinioti C (2010). "Hormonal therapy for acne: why not as first line therapy? facts and controversies". Clin. ... See also: Management of prostate cancer § Hormonal therapy, and Androgen deprivation therapy ...
Music therapy
The creation and expansion of music therapy as a treatment modality thrived in the early to mid 1900s and while a number of ... Schlez A, Litmanovitz I, Bauer S, Dolfin T, Regev R, Arnon S (June 2011). "Combining kangaroo care and live harp music therapy ... Types of music therapyEdit. There are two fundamental types of music therapy: receptive music therapy and active music therapy ... including Therapy in Music for Handicapped Children, Creative Music Therapy, Music Therapy in Special Education, as well as ...
Recidivism
A study was conducted regarding the recidivism rate of inmates receiving MMT (Methadone Maintenance Therapy). This therapy is ... When combined with substance misuse this increases the risk of reoffending significantly.[55] A subset of ASPD, or a related ... state and federal judges have sentenced offenders to learn the Transcendental Meditation program as an anti-recidivism modality ... "International Journal of Offender Therapy and Comparative Criminology. 48 (2): 133-48. doi:10.1177/0306624X03259472. PMID ...
Neuroscience of music
This suggests that the auditory modality can access the motor system.[46][47] While these auditory-motor interactions have ... but little is known about their combined interaction in producing a complex musical performance.[18] The study of music ... Neurologic music therapy. *Neuronal encoding of sound. *Performance science. *Philosophy of music ... Arrhythmia in the auditory modality is defined as a disturbance of rhythmic sense; and includes deficits such as the inability ...
Audio therapy
In contrast and by distinction, audio therapy is provided as a self-service modality, through which the listener is purported ... the Hirsch, C. R., Clark, D. M., and Mathews, A., Imagery and interpretations in social phobia: Support for the combined ... One such discipline is cognitive behavioral therapy. Unlike music therapy, but similar to audio therapy, the most important ... as well as art therapy, music therapy, and dance therapy. Although the means by which the mind affects the body is largely ...
Combination therapy
... or polytherapy is therapy that uses more than one medication or modality . Typically, the term refers to ... Monotherapy has advantages over combining medications in many patients, including absence of drug-drug interactions, fewer side ... although it can also involve non-medical therapy, such as the combination of medications and talk therapy to treat depression ... "Combination Therapies for Cancer - Annual Plan". National Cancer Institute. Retrieved 2017-10-03.. ...
Cholangiocarcinoma
Both positive[71][72] and negative[11][73][74] results have been reported with adjuvant radiation therapy in this setting, and ... Ultrasound of the liver and biliary tree is often used as the initial imaging modality in people with suspected obstructive ... Knox JJ, Hedley D, Oza A, Feld R, Siu LL, Chen E, Nematollahi M, Pond GR, Zhang J, Moore MJ (April 2005). "Combining ... Adjuvant therapy followed by liver transplantation may have a role in treatment of certain unresectable cases.[70] ...
Thoracotomy
Bilateral anterolateral thoracotomy combined with transverse sternotomy results in the "clamshell" incision ... been found to be a good adjunct in the management of moderate to severe post-thoracotomy pain and effective as a lone modality ... Respiratory therapy/. intubation. *Artificial respiration. *CPR. *Hyperbaric medicine. *Decompression chamber. *Heliox. * ...
Posttraumatic stress disorder
... this therapy modality is well supported by clinical evidence.[citation needed] The success of exposure-based therapies has ... Hetrick SE, Purcell R, Garner B, Parslow R (July 2010). "Combined pharmacotherapy and psychological therapies for post ... cognitive restructuring therapy, trauma-focused cognitive behavioral therapy, brief eclectic psychotherapy, narrative therapy, ... Exposure therapy is a type of cognitive behavioral therapy[157] that involves assisting trauma survivors to re-experience ...
Health informatics
... occupational therapy, physical therapy, biomedical research, and alternative medicine,[5][unreliable medical source?] all of ... Clinical informaticians use their knowledge of patient care combined with their understanding of informatics concepts, methods ... supporting the flow of patient information through various modalities of care. ... Seg8 Family/Prenatal/Cumulative Health/Medical/Dental Nursing History, Seg14D Therapies ● S.15 Health guidance. ● Seg10 Care/ ...
Medical genetics
Enzyme replacement therapy. Certain lysosomal storage diseases are treated with infusions of a recombinant enzyme (produced in ... Referral to an out-patient genetics clinic (pediatric, adult, or combined) or an in-hospital consultation, most often for ... translational research on new treatment modalities, and the impact of genetic testing ... In other cases, infusion therapy is used to replace the missing enzyme. Current research is actively seeking to use gene ...
سرطان پروستات - ویکیپدیا، دانشنامهٔ آزاد
... such as pathologic stage and recurrence after surgery or radiation therapy. Most combine stage, grade, and PSA level, and some ... Therefore, there is currently much interest in the role of aggressive prostate cancer treatment modalities such as with surgery ... Active surveillance, surgery, radiation therapy, hormone therapy, chemotherapy[2]. Prognosis. 5-year survival rate 99% (US)[4] ... Androgen ablation therapy causes remission in 80-90% of patients undergoing therapy, resulting in a median progression-free ...
Retina
Common treatment modalities[edit]. The following are commonly modalities of management for retinal disease: *Intravitreal ... Rolling, F. (2004). "Recombinant AAV-mediated gene transfer to the retina: gene therapy perspectives". Gene Therapy. 11 (S1): ... A third view of the "inverted" vertebrate eye is that it combines two benefits: the maintenance of the photoreceptors mentioned ... "Human Gene Therapy. 20 (9): 999-1004. doi:10.1089/hum.2009.086. PMC 2829287. PMID 19583479.. ...
Chemotherapy
Combined modality chemotherapy is the use of drugs with other cancer treatments, such as surgery, radiation therapy, or ... Systemic therapy is often used in conjunction with other modalities that constitute local therapy (i.e. treatments whose ... Importantly, the use of drugs (whether chemotherapy, hormonal therapy or targeted therapy) constitutes systemic therapy for ... Cytotoxics and targeted therapies[edit]. Targeted therapies are a relatively new class of cancer drugs that can overcome many ...
Vertebral artery dissection
No randomized controlled trials have been performed to compare the different treatment modalities.[1][17] Surgery is only used ... Anticoagulation is regarded as more powerful than antiplatelet therapy, but anticoagulants may increase the size of the ... the combined mortality with either treatment is 1.8-2.1%.[1][17] ... Various diagnostic modalities exist to demonstrate blood flow ... Treatment is focused on reducing stroke episodes and damage from a distending artery.[3] Four treatment modalities have been ...
Coeliac disease
Antibody testing may be combined with HLA testing if the diagnosis is unclear. TGA and EMA testing are the most sensitive serum ... Schuppan D, Junker Y, Barisani D (December 2009). "Celiac disease: from pathogenesis to novel therapies". Gastroenterology. 137 ... Three main approaches have been proposed as new therapeutic modalities for coeliac disease: gluten detoxification, modulation ... Selenium malabsorption in coeliac disease, combined with low selenium content in many gluten-free foods, confers a risk of ...
Hives
"Skin Therapy Lett (Review). 18 (7): 5-9. PMID 24305753. Archived from the original on 2016-01-31.. ... In addition, one study found that systemic glucocorticoids combined with antihistamines did not hasten the time to symptom ... "Influence of initial treatment modality on long-term control of chronic idiopathic urticaria". PLoS ONE. 8 (7): e69345. doi ... The mainstay of therapy for both acute and chronic hives is patient education, avoiding triggers and using antihistamines. ...
Developmental language disorder
Grammar - This involves the ability to combine words into grammatically correct sentences (syntax) and to combine parts of ... Gathercole, Susan E. (25 July 2016). "Word learning in language-impaired children". Child Language Teaching and Therapy. 9 (3 ... and two modalities (comprehension and production). Children scoring in the lowest 10% on two or more composite scores are ... "Child Language Teaching and Therapy. 23 (1): 67-93. doi:10.1191/0265659007072143. S2CID 49573186.. ...
Existentialism
Facticity is a concept defined by Sartre in Being and Nothingness as the in-itself, which delineates for humans the modalities ... "Existential-therapy.com. Archived from the original on 2010-01-07. Retrieved 2010-03-08.. ... held that human existence must always be defined as the individual person combined with the concrete circumstances of his life ... Main article: Existential therapy. A major offshoot of existentialism as a philosophy is existentialist psychology and ...
Gestalt psychology
Gestalt therapy[edit]. Gestalt psychology should not be confused with the Gestalt therapy, which is only peripherally linked to ... These laws deal with the sensory modality of vision. However, there are analogous laws for other sensory modalities including ... Similarities between symmetrical objects increase the likelihood that objects are grouped to form a combined symmetrical object ... Joe Wysong/Edward Rosenfeld (eds): An Oral History of Gestalt Therapy, Highland, New York 1982, The Gestalt Journal Press, p. ...
Medical ultrasound
This contrast medical imaging modality is clinically used throughout the world,[32] in particular for echocardiography in the ... In angiology or vascular medicine, duplex ultrasound (B Mode imaging combined with Doppler flow measurement) is used to ... Metastatic thyroid cancer neck lymph nodes: The other thyroid therapy use for HFUS is to treat metastatic thyroid cancer neck ... Color Doppler images are generally combined with grayscale (B-mode) images to display duplex ultrasonography images. Uses ...
Sensory processing disorder
Sensory processing therapy[edit]. This therapy retains all of the above-mentioned four principles and adds:[45] ... The senses provide information from various modalities-vision, audition, tactile, olfactory, taste, proprioception, ... The main form of sensory integration therapy is a type of occupational therapy that places a child in a room specifically ... Sensory Integration Therapy and Auditory Integration Therapy" (PDF).. *^ "Sensory Processing Disorder (SPD) and Social Security ...
專注力失調或過度活躍症 - 維基百科,
規律的體能鍛煉,特別是有氧運動,對於患有ADHD的兒童及成人而言也是有效的附加療法(英語:adjunct therapy),特別是配合興奮劑藥物治療時更是如此,不過針對改善徵狀,最理想的運動種類及強度還不清楚[164][165][166]。長期規律有氧運 ... Effect of treatment modality on long-term outcomes in attention-deficit/hyperactivity disorder: a systematic review. PLOS
Warfarin
When initiating warfarin therapy ("warfarinization"), the doctor will decide how strong the anticoagulant therapy needs to be. ... No specific treatment is available, but some modalities are under investigation.[45] ... The risks of bleeding are increased further when warfarin is combined with antiplatelet drugs such as clopidogrel, aspirin, or ... Gage BF, Fihn SD, White RH (October 2000). "Management and dosing of warfarin therapy". The American Journal of Medicine. 109 ( ...
combined modality therapy
Modification of Radiosensitivity Following Chemotherapy Exposure: Potential Implications for Combined-Modality Therapy |...
Cervical Cancer Radiation Response Small Cell Lung Cancer Cell Combine Modality Therapy Human Ovarian Cancer Cell Line These ... Sersa G, Kranjc S, Cemazar M. Improvement of combined modality therapy with cisplatin and radiation using electroporation of ... Modification of Radiosensitivity Following Chemotherapy Exposure: Potential Implications for Combined-Modality Therapy. ... Potential Implications for Combined-Modality Therapy. In: Andersson B., Murray D. (eds) Clinically Relevant Resistance in ...
Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma - Full Text View - ClinicalTrials.gov
Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma. The safety and scientific validity of this study is the ... Combined modality therapy in PCNSL has improved survival outcomes but at the cost of unacceptable rates of neurotoxicity when ... A Phase 2 Study of Idarubicin Based Combined Modality Therapy in Primary Central Nervous System Lymphoma. ... By combining these 2 drugs with moderate dose radiotherapy survival outcomes should be optimal but with lower rates of ...
PRIME PubMed | [Combined-modality therapy for 150 cases of early-stage Hodgkin's lymphoma
Combined-modality therapy for 150 cases of early-stage Hodgkins lymphoma were found in PRIME PubMed. Download Prime PubMed App ... Combined-modality Therapy for 150 Cases of Early-stage Hodgkins Lymphoma]." Zhonghua Zhong Liu Za Zhi [Chinese Journal of ... Combined-modality Therapy for 150 Cases of Early-stage Hodgkins Lymphoma]. Zhonghua Zhong Liu Za Zhi. 2008;30(8):630-4. PubMed ... Combined-modality therapy for 150 cases of early-stage Hodgkins lymphoma].. Zhonghua Zhong Liu Za Zhi 2008; 30(8):630-4ZZ ...
Docetaxel and Radiation as Combined-Modality Therapy | Cancer Network | The Oncology Journal
Combined-modality approaches for the treatment of non-small-cell lung cancer (NSCLC), head and neck cancer, and esophageal ... combined-modality therapy.. Background. The taxanes are a class of antineoplastic agents, derived from plants, that. have ... Mauer AM, Haraf DC, Ferguson MK, et al: Docetaxel-based combined modality. therapy for locally advanced carcinoma of the ... have included single modalities such as surgery, radiation, or chemotherapy.. Combined modality approaches offer a theoretical ...
Combined-Modality Therapy for Head and Neck Cancer | Cancer Network | The Oncology Journal
... when combined with radiotherapy and/or surgery in the treatment of patients with head and neck cancer, appears to be most ... This paper presents an overview of the results of randomized trials of combined-modality therapy for advanced head and neck ... Lo TC, Wiley AL, Jr., Ansfield FJ, et al: Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of ... Adelstein DJ, Sharan VM, Earle AS, et al: Simultaneous versus sequential combined technique therapy for squamous cell head and ...
Multi-Modality Therapy for Mesothelioma | Combining Treatment Options
Multi-Modality Therapy combines more than one method of mesothelioma cancer treatment. See latest statistics on lab testing and ... Tri-modality mesothelioma treatment combines several different types of therapies. The goal is to attack mesothelioma from ... Surviving Mesothelioma / News / Multi-Modality Therapy. Inflammation Protein May Impact Drug Therapies for Mesothelioma May 24 ... Triple-Modality Therapy May Improve Mesothelioma Outcomes, Study Suggests April 18, 2021. Alex Strauss ...
Combined Modality Therapy of Gastrointestinal Tract Cancer | SpringerLink
Modern surgical oncology is characterized by multimodal therapy. In recent years numerous therapeutic approaches of pre-, peri ... Combined Therapy in Gastric Cancer. * Phase-III Clinical Trial of Adjuvant FAM2 (5-FU, Adriamycin and Mitomycin C) vs Control ... Combined Therapy in Esophageal Cancer. * The Value of Preoperative Radiotherapy in Esophageal Cancer: Results of a Study by the ... Combined Therapy in Colorectal Cancer. * Adjuvant Portal Infusion Chemotherapy in Colorectal Cancer ...
A Phase II Study of Combine Modality Therapy in Locally Advanced Pancreatic Cancer - Full Text View - ClinicalTrials.gov
A Phase II Study of Combine Modality Therapy in Locally Advanced Pancreatic Cancer. The safety and scientific validity of this ... Because patients with immune deficiency are at increased risk of lethal infections when treated with marrow-suppressive therapy ... Appropriate studies will be undertaken in patients receiving combination anti-retroviral therapy when indicated. ... HIV-positive patients receiving combination anti-retroviral therapy are excluded from the study because of possible ...
Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer - Full Text View -...
I. To evaluate whether therapy with nivolumab following combined modality therapy (CMT) improves disease-free survival (DFS) ... Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer. The safety and ... A Randomized Phase II Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer. ... This randomized phase II clinical trial studies how well nivolumab after combined modality therapy works in treating patients ...
IJMS | Free Full-Text | Biomarkers of Treatment Toxicity in Combined-Modality Cancer Therapies with Radiation and Systemic...
In view of the complexity of biological responses to cancer therapy, this communication reports on a ... Organ toxicity in cancer therapy is likely caused by an underlying disposition for given pathophysiological mechanisms in the ... Ree AH, Meltzer S, Flatmark K, Dueland S, Kalanxhi E. Biomarkers of Treatment Toxicity in Combined-Modality Cancer Therapies ... Biomarkers of Treatment Toxicity in Combined-Modality Cancer Therapies with Radiation and Systemic Drugs: Study Design, ...
Combined Modality Therapy | Profiles RNS
"Combined Modality Therapy" by people in this website by year, and whether "Combined Modality Therapy" was a major or minor ... "Combined Modality Therapy" by people in Profiles.. * Ko EC, Formenti SC. Radiation therapy to enhance tumor immunotherapy: a ... "Combined Modality Therapy" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are MeSH descriptors whose meaning is more general than "Combined Modality Therapy". ...
Combined Modality Therapy For Locally Advanced Non-Small Cell Lung Cancer - Non-Small Cell Lung Cancer and Tracheal Cancer:...
Adjuvant Therapy for Non-Small Cell Lung Cancer14:58. Combined Modality Therapy For Locally Advanced Non-Small Cell Lung Cancer ... Combined Modality Therapy For Locally Advanced Non-Small Cell Lung Cancer. To view this video please enable JavaScript, and ... This lecture is going to be dealing with the combined-modality therapy for patients with locally advanced non-small cell lung ... Majority of people will undergo combined-modality therapy with a curative intent. Cure is achieved in approximately 20 percent ...
Functional and quality-of-life outcomes in patients with rectal cancer after combined modality therapy, intraoperative...
Functional and quality-of-life outcomes in patients with rectal cancer after combined modality therapy, intraoperative ... The majority of patients with advanced rectal cancers who require external beam radiation therapy, extensive pelvic surgery, ... Locally advanced primary and recurrent rectal cancers treated with external beam radiation therapy, intraoperative radiation ... and intraoperative radiation therapy report unfavorable functional and quality-of-life outcomes after sphincter preservation. ...
Combined modality therapy for esophageal cancer<...
Blanke, C. D. ; Choy, H. ; Leach, S. D. / Combined modality therapy for esophageal cancer. In: Seminars in Radiation Oncology. ... Blanke, C. D., Choy, H., & Leach, S. D. (1997). Combined modality therapy for esophageal cancer. Seminars in Radiation Oncology ... Blanke, CD, Choy, H & Leach, SD 1997, Combined modality therapy for esophageal cancer, Seminars in Radiation Oncology, vol. 7 ... Combined modality therapy for esophageal cancer. Seminars in Radiation Oncology. 1997;7(3 SUPPL. 2):15-23. ...
Combined modality therapy | definition of combined modality therapy by Medical dictionary
What is combined modality therapy? Meaning of combined modality therapy medical term. What does combined modality therapy mean? ... Looking for online definition of combined modality therapy in the Medical Dictionary? combined modality therapy explanation ... Combined modality therapy, Concentration therapy, Concept therapy, Condom therapy, Confrontation therapy, Conservative therapy ... neoadjuvant therapy in single-agent therapy or combined modality therapy for cancer, initial use of one modality, such as ...
The pattern of recurrence and survival after treatment failure in patients with rectal cancer treated with combined modality...
The pattern of recurrence and survival after treatment failure in patients with rectal cancer treated with combined modality ... of recurrence and survival after treatment failure in patients with rectal cancer treated with combined modality therapy. ... Although surgery is the cornerstone curative treatment, combined modalities with radiotherapy and or chemotherapy have been ... The definitive treatment with the combined modalities including surgery, radiotherapy, and chemotherapy have significantly ...
Combined-modality therapy for pulmonary alveolar proteinosis in a remote setting: a case report | BMC Pulmonary Medicine | Full...
We posit that this combined-modality therapy is ideally suited to geographically-remote centers such as our own. ... The autoimmune form of PAP is the most common, indicating that therapy with GM-CSF may play an important role for many patients ... Additional sequential lobar lavage and continued GM-CSF therapy as an outpatient resulted in complete resolution of oxygen ... Treatment with WLL may be impractical in some clinical settings due to the expertise and salvage modalities required. ...
Combined modality therapy of esophageal cancer<...
Combined modality therapy of esophageal cancer. Together they form a unique fingerprint. * Combined Modality Therapy Medicine ... Combined modality therapy of esophageal cancer. / Juergens, Rosalyn A.; Forastiere, Arlene.. In: JNCCN Journal of the National ... Combined modality therapy of esophageal cancer. JNCCN Journal of the National Comprehensive Cancer Network. 2008 Oct;6(9):851- ... Combined modality therapy of esophageal cancer. In: JNCCN Journal of the National Comprehensive Cancer Network. 2008 ; Vol. 6, ...
Combined modality therapy in non-small cell lung cancer<...
Blanke, C., & Johnson, D. H. (1995). Combined modality therapy in non-small cell lung cancer. Current Opinion in Oncology, 7(2 ... Blanke, C & Johnson, DH 1995, Combined modality therapy in non-small cell lung cancer, Current Opinion in Oncology, vol. 7, ... Blanke, Charles ; Johnson, D. H. / Combined modality therapy in non-small cell lung cancer. In: Current Opinion in Oncology. ... title = "Combined modality therapy in non-small cell lung cancer",. abstract = "Lung cancer kills more Americans annually than ...
Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology...
Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology ... Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology ... Mohiuddin, M; Winter, K; Mitchell, E; Hanna, N; Yuen, A; Nichols, C; Shane, R; Hayostek, C; Willett, C; Radiation Therapy ... 120 hours per week plus irinotecan 50 mg/m2 once weekly for 4 weeks plus pelvic radiation therapy 50.4 to 54 Gy at 1.8 Gy per ...
LLS Search Results | Leukemia and Lymphoma Society
For example, treating a patient with chemotherapy and involved field radiation therapy is a combined modality therapy. ... Combined Modality Therapy. Two or more types of treatment used alternately or at the same time to treat a patients disease. ... Induction therapy The initial treatment with chemotherapy (or radiation therapy). The aim of induction therapy is to kill a ... Postremission Therapy. The treatment given to ALL patients after induction therapy. Postremission therapy may have two parts: ...
Story Lab - UT Southwestern
Combined modality therapy. The third area of biology we are focused on is referred to as combined modality therapy. Our goal is ... We are examining circulating miRNA for response to therapy and metastatic potential using a relatively non-invasive method. And ... center at UT Southwestern that includes the construction of a proton therapy center as well as a heavy particle therapy center ... and medicine that will contribute to the use of heavy particles for therapy. We are collaborating with the GSI Helmholtz Centre ...
Download Combined Modality Therapy Of Central Nervous System Tumors
... The download combined modality therapy of of Malory ... This recipient public download combined modality therapy of, of gp, is moved in the Idyll. This download combined modality will ... Can I use or Exchange a download combined modality therapy of central after I suggest it? Because the download combined ... The download combined modality therapy and formula of Lancelot pass up to the later paper of his language. But this course is ...
Plus it
Single-modality therapy does not have a major impact on long-term survival and combined-modality therapies are being further ... Combined-modality therapy. Even 30 years ago, it was clear that MPM is difficult to treat and that, for most patients, there is ... Is trimodal therapy a valid option for patients with mesothelioma that is technically resectable? Different combined-modality ... Further prospective trials are required to determine optimal combined modality therapy in mesothelioma. Hopefully, the ...
Health Information Center
Combined Modality Therapy. Most times, pancreatic cancer is discovered at an advanced stage. Surgery may not be appropriate in ... Radiation Therapy. This is the use of radiation to kill cancer cells and shrink tumors. Radiation therapy may be:. *External- ... The physical exam combined with all of your test results, will help to determine the stage of cancer you have. Staging is used ... Biological Therapy. The use of medications or substances made by the body. They can increase or restore the bodys natural ...
Combined modality therapy for thoracic and head and neck cancers: A review of updated literature based on a consensus meeting<...
Combined modality therapy for thoracic and head and neck cancers: A review of updated literature based on a consensus meeting. ... Combined modality therapy for thoracic and head and neck cancers : A review of updated literature based on a consensus meeting. ... T1 - Combined modality therapy for thoracic and head and neck cancers. T2 - A review of updated literature based on a consensus ... Combined modality therapy for thoracic and head and neck cancers: A review of updated literature based on a consensus meeting. ...
Evaluation of treatment modalities for septic arthritis with histological grading and analysis of levels of uronic acid,...
Each modality has its proponents, but, to our knowledge, no comparative studies have been conducted in animals … ... Combined Modality Therapy * Drainage * Female * Goats * Interleukin-1 / analysis * Knee Joint* * Male ... Each modality has its proponents, but, to our knowledge, no comparative studies have been conducted in animals. We used ... Evaluation of treatment modalities for septic arthritis with histological grading and analysis of levels of uronic acid, ...
Gallbladder Cancer | Denver Health
Combined Modality Therapy (CMT). CMT is a term gaining popularity and meaning several treatments at once or in succession. ... Combined Modality Therapy (CMT). CMT is a term gaining popularity and meaning several treatments at once or in succession. ... Radiation Therapy. Radiation therapy uses radiation to kill cancer cells and shrink tumors. Radiation is most often ... Radiation Therapy. Radiation therapy uses radiation to kill cancer cells and shrink tumors. Radiation is most often ...
WHO HQ Library catalog › Details for: Combined modality therapy of gastrointestinal tract cancer /
RadiotherapyTherapeuticSurvivalGastrointestinalSingle-modality therapyIrradiationTumorChemoradiotherapyTreatmentPatients with rectal cancerChemoradiationMulti-modalityDifferent modalitiesImmunotherapyTherapeuticsCarcinomaAdjuvantDrug TherapyMalignanciesOutcomesPreoperative combinedCancer TherapiesVersusRectalCancersTumorsPulmonaryRadiation TheraSurgical resectionTreatmentsSurgeryLymphomaDiagnosticPCNSLSystemicRecurrenceStereotactic body radiation therapyIntraoperative radiatiAggressiveInvestigationalPositron-Emission TDescriptorNeoadjuvant therapyPhotodynamic therapyLungUltrasoundApproaches
Radiotherapy21
- Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additivity. (springer.com)
- Idarubicin combined with high dose methotrexate and moderate dose radiotherapy will achieve similar survival outcomes but with reduced neurotoxicity compared to regimens using methotrexate with high dose radiotherapy. (clinicaltrials.gov)
- Combined modality therapy in PCNSL has improved survival outcomes but at the cost of unacceptable rates of neurotoxicity when high dose radiotherapy is used. (clinicaltrials.gov)
- By combining these 2 drugs with moderate dose radiotherapy survival outcomes should be optimal but with lower rates of neurotoxicity. (clinicaltrials.gov)
- To compare the efficacy of chemotherapy alone, radiotherapy alone and combined-modality therapy in the treatment for early-stage Hodgkin's lymphoma (HL). (unboundmedicine.com)
- They were stratified into several groups based on initial treatment strategy: chemotherapy alone (CT group, n = 22), radiotherapy alone (RT group, n = 18), combined-modality therapy (CMT group, n = 109) and surgical resection (SR group, n = 1). (unboundmedicine.com)
- Combined-modality therapy is more effective than chemotherapy alone or radiotherapy alone in the treatment for early stage Hodgkin's lymphoma. (unboundmedicine.com)
- A Canadian study suggests that triple-modality therapy with radiotherapy, immunotherapy, and surgery may extend the lives of people with malignant pleural mesothelioma. (survivingmesothelioma.com)
- Although surgery is the cornerstone curative treatment, combined modalities with radiotherapy and or chemotherapy have been proved to be an important component of treatments for locally advanced rectal cancer including Stage II and Stage III in terms of decreased local recurrence and increased overall survival in addition to surgical resection. (alliedacademies.org)
- Although total mesorectal excision (TME) has resulted in a significant reduction of local recurrence, neoadjuvant or adjuvant radiotherapy with or without chemotherapy is still an important modality for local control in the era of TME. (alliedacademies.org)
- The definitive treatment with the combined modalities including surgery, radiotherapy, and chemotherapy have significantly improved the treatment outcomes of patients with rectal cancer but cancer recurrence of both local regional and distant is still significant ( 1 - 9 ). (alliedacademies.org)
- Majority of the patients received tri-modality of treatments either neoadjuvant chemo-radiotherapy followed by definitive surgery (n=152) or surgery followed by adjuvant chemo-radiotherapy (n=117). (alliedacademies.org)
- After aggressive treatments which included surgical resection alone or combined with radiotherapy and or chemotherapy, long term survivors were identified with 3 patients who had isolated local recurrence and who have survived 8 to 11 years without evidence of further recurrence. (alliedacademies.org)
- Seung, SK & Ross, HJ 2009, ' Phase II Trial of Combined Modality Therapy With Concurrent Topotecan Plus Radiotherapy Followed by Consolidation Chemotherapy for Unresectable Stage III and Selected Stage IV Non-Small-Lung Cancer ', International Journal of Radiation Oncology Biology Physics , vol. 73, no. 3, pp. 802-809. (elsevier.com)
- Comparative effectiveness of radical prostatectomy with adjuvant radiotherapy versus radiotherapy plus androgen deprivation therapy for men with ad. (nih.gov)
- Clinical guidelines support multimodal approaches, which include radical prostatectomy (RP) followed by radiotherapy (XRT) and XRT plus androgen deprivation therapy (ADT). (nih.gov)
- Capecitabine has also been investigated in a variety of protocols in rectal and other gastrointestinal cancers in combination with radiotherapy [ 16 ], with equivalence of capecitabine plus radiotherapy and 5-FU plus radiotherapy as preoperative therapy in locally advanced rectal cancer being demonstrated in the systematic review by Saif et al. (springer.com)
- A prospective study of the safety and efficacy of liver stereotactic body radiotherapy in patients with and without prior liver-directed therapy. (unc.edu)
- Anal Carcinoma Therapy: Can We Improve on 5-Fluorouracil/Mitomycin/Radiotherapy? (jnccn.org)
- stages II-IV) were treated with definitive chemoradiotherapy using 5-fluorouracil and cisplatin combined with radiotherapy. (aacrjournals.org)
- A phase III trial from the United States (Radiation Therapy Oncology Group trial 85-01) showed that adding 5-fluorouracil and cisplatin (FP) combination chemotherapy to radiotherapy is superior to radiotherapy alone in patients with locally advanced esophageal cancer ( 1 - 3 , 5 , 6 ). (aacrjournals.org)
Therapeutic6
- In view of the complexity of biological responses to cancer therapy, this communication reports on a "top-down" strategy, starting with the systematic assessment of adverse effects within a defined therapeutic context and proceeding to transcriptomic and proteomic analysis of relevant patient tissue samples and computational exploration of the resulting data, with the ultimate aim of utilizing information from functional connectivity networks in evaluation of patient safety in multimodal cancer therapy. (mdpi.com)
- Hoag's committed to accurate diagnosis, combined with progressive therapeutic options enables Hoag patients to achieve some of the highest clinical outcomes in the nation. (hoag.org)
- This model recapitulates radiation-resistant prostate cancers which can be used to demonstrate and quantify therapeutic response to combined modality treatments. (elsevier.com)
- A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. (bioportfolio.com)
- Thus, the positive impact of IORT on local control of colorectal cancer appears to justify the inclusion of this therapeutic modality. (aetna.com)
- Many targeted therapies are examples of immunotherapy (using immune mechanisms for therapeutic goals) developed by the field of cancer immunology. (wikipedia.org)
Survival18
- 1] The survival for those with early-stage disease (T1-2, N0, M0) is acceptable, with 5-year survival rates of 70% to 90% with single-modality therapy. (cancernetwork.com)
- Locally or regionally advanced (T3-4, N0-3) disease has historically been treated with combined-modality therapy to maximize local control and survival. (cancernetwork.com)
- The addition of surgery following primary combined-modality therapy apparently does not improve survival, but this finding is controversial. (cancernetwork.com)
- I. To evaluate whether therapy with nivolumab following combined modality therapy (CMT) improves disease-free survival (DFS) compared with observation in patients with high risk anal carcinoma. (clinicaltrials.gov)
- Stage III non-small cell is a curable disease with a five-year overall survival rate in the 15-25 percent range with current therapy. (coursera.org)
- results have been equivocal, with response and survival rates similar to those of single modality therapy. (elsevier.com)
- Some studies evaluating chemotherapy followed by surgery have resulted in improved partial response rates (17%-57%), with median survival similar to single modality treatment. (elsevier.com)
- In two randomized trials, the combination of chemotherapy and surgery was not superior to single modality therapy in terms of response and survival. (elsevier.com)
- The combined chemoradiotherapy approach, versus single-modality chemotherapy or irradiation, has improved on survival. (elsevier.com)
- Single-modality therapy does not have a major impact on long-term survival and combined-modality therapies are being further evaluated. (ersjournals.com)
- After surgery, follow-up chemotherapy and radiation therapy have been found to prolong survival in some cases. (epnet.com)
- Surgery is still regarded as the principle modality among treatment strategies, with longterm survival achieved mainly in less advanced cases. (knowcancer.com)
- A case of long-term survival due to combined modality therapy for liver metastasis of colon cancer]. (elsevier.com)
- Systemic symptoms, histologic subtype, age, and limited extranodal involvement (E-lesions) did not affect the prognosis of patients and failed to identify patients whose survival could be improved by the routine use of combined modality therapy. (ashpublications.org)
- Purpose: Standard therapy for patients with stage I-II indolent lymphoma has been involved-field radiation therapy (IF-XRT), which achieves 10-year disease-free survival in 40% to 50% of patients/ with many of these patients cured. (northwestern.edu)
- We investigated the potential for combined-modality therapy to increase the disease-free survival for such patients. (northwestern.edu)
- Conclusion: With prolonged follow-up, combined-modality therapy with risk-adapted COP-/CHOP-Bleo and IF radiation has attained higher rates of disease control and survival than previously reported with IF-XRT alone. (northwestern.edu)
- Erlotinib has been shown to increase survival in metastatic non small cell lung cancer when used as second line therapy. (wikipedia.org)
Gastrointestinal1
- Combined modality therapy of gastrointestinal tract cancer / P. Schlag, P. Hohenberger, U. Metzger (eds. (who.int)
Single-modality therapy2
- Single modality therapy for esophageal cancer usually consists of surgery or radiation therapy. (elsevier.com)
- Single-modality therapy is the standard for most cases of limited and metastatic non-small cell lung cancer, but treatment of locally advanced disease remains controversial. (elsevier.com)
Irradiation5
- Moreover, we do not know from these trials what is the added value of irradiation in a combined modality therapy over a preoperative chemotherapy. (knowcancer.com)
- Freedom from relapse at 10 yr was 77% among patients treated with irradiation alone and 84% after treatment with combined modality therapy [p(Gehan) = 0.09]. (ashpublications.org)
- Patients with large mediastinal masses (mediastinal mass ratio greater than or equal to 1/3) had a significantly poorer freedom from relapse when treated with irradiation alone than when treated initially with combined modality therapy [45% versus 81% at 10 yr, p(Gehan) = 0.03). (ashpublications.org)
- Radiation oncology only minimally takes the genetic makeup of tumors into account, and little attention has been given to the fact that the different modalities of ionizing radiation, such as photon and proton irradiation, may also induce differential damages and biological processes, which might again be influenced by the genetic makeup and mutational status of the tumor. (allenpress.com)
- Here we will review recent insights on the differential DNA damage responses to photon and proton irradiation and discuss their implications for combined treatment modalities with chemotherapeutical agents and small molecular targeting compounds. (allenpress.com)
Tumor15
- It begins with an aggressive resection of the visible tumor then following it with Radiation Therapy (RT) given together with chemotherapy. (bcan.org)
- Radiation therapy to enhance tumor immunotherapy: a novel application for an established modality. (umassmed.edu)
- We report the case in which the tumor-free status can be observed as a result of a combination of systemic chemotherapy and local therapy. (elsevier.com)
- Moreover, by combining the mRNA vaccines with therapies in clinical use (chemotherapy or anti-CTLA-4 antibody therapy), an even more effective anti-tumor response can be elicited. (wiley.com)
- Hence, current treatment decisions for particle beam therapy are primarily based on vulnerable tumor locations near organs-at-risk, and treated entities comprise uveal melanoma, skull-based and intracranial tumors, prostate and head and neck tumors [ 8 , 9 ]. (allenpress.com)
- Operation, chemotherapy, and rays therapy are regular modalities for tumor treatment, however the effectiveness of the treatments has already reached a plateau. (complextraitgenomics.com)
- Management of NMIBC, traditionally, has been focused on the reduction of subsequent bladder recurrence and prevention of disease progression and is primarily based on transurethral resection (TUR) of the tumor, followed by intravesical therapy based on estimated individual risk of recurrence. (srce.hr)
- The intent of vaccination is to induce a combined antibody and T-cell anti-HER-2 immune response, which is intended to target HER-2-expressing tumor cells, and may induce tumor regression or slow progression of disease. (stanford.edu)
- The primary purpose of this study is to determine whether breast cancer tumors respond (as measured by pathologic complete response: the absence of microscopic evidence of invasive tumor cells in the breast) to combined chemotherapy of AC(doxorubicin and cyclophosphamide) followed by paclitaxel plus trastuzumab or lapatinib or both given before surgery to patients with HER2-positive breast cancer. (stanford.edu)
- Depletion of Tumor Oxygenation during Photodynamic Therapy: Detection by the Hypoxia Marker EF3. (upenn.edu)
- Intra-operative radiation therapy (IORT) is being investigated as a technique to deliver a high dose of radiation to a locally advanced tumor while attempting to protect adjacent normal tissues at the time of surgery. (aetna.com)
- DTI assessment of the brainstem white matter tracts in pediatric BSG before and after therapy: a report from the Pediatric Brain Tumor Consortium. (harvard.edu)
- As a form of molecular medicine, targeted therapy blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth, rather than by simply interfering with all rapidly dividing cells (e.g. with traditional chemotherapy). (wikipedia.org)
- Another form of targeted therapy involves the use of nanoengineered enzymes to bind to a tumor cell such that the body's natural cell degradation process can digest the cell, effectively eliminating it from the body. (wikipedia.org)
- The definitive experiments that showed that targeted therapy would reverse the malignant phenotype of tumor cells involved treating Her2/neu transformed cells with monoclonal antibodies in vitro and in vivo by Mark Greene's laboratory and reported from 1985. (wikipedia.org)
Chemoradiotherapy5
- He describes the data in favor of primary chemoradiotherapy without surgery and concludes that combined use of chemotherapy and radiation is the standard of care for patients found to have squamous cell cancers or adenocarcinoma. (cancernetwork.com)
- Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used. (umassmed.edu)
- PURPOSE: To evaluate the rate of pathologic complete response and toxicity of neoadjuvant chemoradiation for advanced T3/T4 distal rectal cancers in a randomized phase II study PATIENTS AND METHODS: Patients with clinical T3/T4 distal rectal cancers were randomly assigned in a phase II study to receive combined neoadjuvant chemoradiotherapy followed by surgical resection. (duke.edu)
- One of the options for improving treatment outcome in patients with advanced esophageal cancer is combined modality treatment with chemo- and chemoradiotherapy. (knowcancer.com)
- That were the reasons for designing our trial testing 3 principal modes of esophageal cancer therapy: surgery vs. chemotherapy + surgery vs. chemoradiotherapy + surgery on homogenous population of esophageal cancer patients with single pathological type - squamous cell carcinoma affecting thoracic esophagus. (knowcancer.com)
Treatment40
- Based on positive results from the Radiation Therapy Oncology Group (RTOG) 85-01 trial, the conventional nonsurgical treatment of esophageal carcinoma is combined-modality therapy. (cancernetwork.com)
- Areas of clinical investigation include the development of combined-modality therapy regimens with newer systemic agents, the use of 18F-fluorodeoxyglucose positron-emission tomography to assist in the development of innovative radiation treatment planning techniques, and the identification of prognostic molecular markers. (cancernetwork.com)
- Treatment approaches for operable stages of these GI cancers focus on determining the usefulness of neoadjuvant and adjuvant therapies. (cancernetwork.com)
- A comparison of chemotherapy alone versus surgery-based tri-modality treatment for mesothelioma shows patients who take the more aggressive path tend to live much longer. (survivingmesothelioma.com)
- Tri-modality mesothelioma treatment combines several different types of therapies. (survivingmesothelioma.com)
- Surgery-Based Tri-Modality Mesothelioma Treatment Pleural mesothelioma is a fast-growing malignancy on the lining around the lungs. (survivingmesothelioma.com)
- collapse therapy a formerly common treatment for pulmonary tuberculosis in which the diseased lung was collapsed in order to immobilize it and allow it to rest. (thefreedictionary.com)
- convulsive therapy treatment of mental disorders, primarily depression, by induction of convulsions . (thefreedictionary.com)
- Whole lung lavage (WLL) is the treatment of choice in symptomatic PAP, but transient worsening of oxygenation sometimes requires salvage modalities of support such as extracorporeal membrane oxygenation (ECMO). (biomedcentral.com)
- Treatment with WLL may be impractical in some clinical settings due to the expertise and salvage modalities required. (biomedcentral.com)
- The prognosis of patients with malignant pleural mesothelioma remains poor and although it is clear that multimodal therapy is necessary to improve long-term results, precise treatment schemes have not yet been unequivocally established. (ersjournals.com)
- Further treatment options that are currently explored include hyperthermic intrapleural chemotherapy, immunotherapy, gene therapy and photodynamic therapy. (ersjournals.com)
- Although it has not been shown that chemo- and radiation therapy at the same time are better than radiation therapy alone in the treatment of gallbladder cancer, CMT is better with many other kinds of cancers. (epnet.com)
- The combined modality therapy approach, including the medical, surgical and radiation arms of cancer therapy, provides the best treatment options for the management of a wide variety of cancer patients with complex problems. (utsouthwestern.edu)
- As a nationally recognized leader in state-of-the-art radiation therapies, Hoag's radiation oncology program is yet another example of the institute's commitment to excellence in innovative cancer treatment. (hoag.org)
- Although no one has shown that chemotherapy and radiation therapy at the same time are better than radiation therapy alone in the treatment of gallbladder cancer, CMT is better with many other kinds of cancers. (hoag.org)
- By combining different treatment modalities cell killing was further enhanced due to interacting sublethal damage. (ki.se)
- Surgery may be the only treatment, or it may be done in combination with radiation therapy and/or chemotherapy. (upstate.edu)
- In the guideline for the treatment of liver metastasis of colorectal cancer, even though chemotherapy is currently developed, the surgical procedure is recommended for patients who are responsive to local therapy. (elsevier.com)
- However, radiation oncology is nowadays challenged to understand subtle differences induced by the different qualities of ionizing radiation, and to efficiently exploit and to integrate these differential responses in a personalized treatment approach alone and as part of combined treatment modalities with pharmacologic agents. (allenpress.com)
- Complications, oncological and functional outcomes of salvage treatment options following focal therapy for localized prostate cancer: a systematic review and a comprehensive narrative review. (bioportfolio.com)
- Radiation therapy is considered a standard treatment option for the management of localized prostate cancer. (bioportfolio.com)
- Patients with stage III prostate cancer are curable and have a number of treatment options, including external beam radiation therapy (EBRT) with or without hormone therapy, surgical removal of the cancer with radical prostatectomy, or active surveillance without immediate treatment. (yourcancercare.com)
- It is important for patients to obtain as much information as possible about the results of each treatment modality and to obtain more than one opinion on the matter, especially when deciding on surgery versus radiation therapy. (yourcancercare.com)
- The current standard treatment for stage III prostate cancer is external beam radiation therapy (EBRT) in conjunction with long-term androgen deprivation therapy (ADT). (yourcancercare.com)
- Treatment with surgery or radiation is referred to as local therapy because they treat prostate cancer in or near the prostate only. (yourcancercare.com)
- An effective treatment is needed to cleanse the body of micrometastases in individuals at high risk of recurrence after local therapy. (yourcancercare.com)
- Another form of treatment, usually hormone therapy, radiation therapy or participation in a clinical study is generally recommended. (yourcancercare.com)
- Of particular interest are adjuvant therapy, treatment of metastatic disease, methods for treatment of locally advanced breast cancer and inflammatory breast cancer. (stanford.edu)
- Encouraging outcomes have been achieved with a combined-modality treatment approach for patients with locally recurrent colorectal cancer in both curative and palliative settings, although room for im. (ascopost.com)
- Aetna considers intraoperative radiation therapy (IORT) medically necessary for the treatment of cervical cancer, colorectal cancer, soft tissue sarcoma (including retroperitoneal sarcoma), and uterine cancer. (aetna.com)
- Intra-operative radiation therapy is usually a component of a multi-disciplinary treatment approach for localized cancers that can not be completely removed or that have a high risk of recurring in nearby tissues. (aetna.com)
- The Stanford Cancer Center states, 'In some cases, no further radiation treatment is required following IORT making it a much more convenient approach for delivering therapy. (aetna.com)
- Till 1970s, surgery was the primary modality of treatment of HB. (centerwatch.com)
- He also specializes in the treatment of esophageal tumors and has led national clinical trials in both therapy of brain tumors as well as esophageal cancer. (hopkinsmedicine.org)
- For localized gastroesophageal cancer, progress has been made with the implementation of multidisciplinary approaches that lead to better selection of therapy for a specific patient, formulation of long-term strategies, and emergence of new standards.4-6 Multidisciplinary interactions can lead to new research strategies and improved understanding of the philosophies used by individual disciplines for treatment decisions. (jnccn.org)
- Progress in the treatment of early gastroesophageal carcinomas using endoscopic therapies is also worth mentioning.7-10 Endoscopic therapy of early cancer seems to be spreading in non-academic centers as well. (jnccn.org)
- His training includes international experience at the Heidelberg University Hospital in Heidelberg, Germany, focused on technique and delivery of particle therapy, specifically proton and carbon treatment. (medstarhealth.org)
- His research focuses on the development of novel radiation therapy techniques and reduction in treatment-related side effects. (medstarhealth.org)
- Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, others being hormonal therapy and cytotoxic chemotherapy. (wikipedia.org)
Patients with rectal cancer1
- Functional and quality-of-life outcomes in patients with rectal cancer after combined modality therapy, intraoperative radiation therapy, and sphin. (nih.gov)
Chemoradiation2
- Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology Group Trial 0012. (duke.edu)
- Use of definitive chemoradiation as primary therapy for locoregional squamous cell carcinoma of the anal canal has been the standard approach in the United States since the 1980s. (jnccn.org)
Multi-modality2
- This article provides a critical review of the data on multi-modality approaches to the management of esophageal cancer. (elsevier.com)
- An integrated, multi-modality imaging technique is disclosed. (google.com)
Different modalities1
- More particularly, the invention relates to an integrated system that makes use of different modalities in a complementary fashion to permit feedback to surgeons and other medical professionals of physical conditions of a subject, particularly during interventionary procedures. (google.com)
Immunotherapy1
- Ko E. Eric Ko on Combining Radiation Therapy With Immunotherapy to Treat Non-Small-Cell Lung Cancer. (umassmed.edu)
Therapeutics1
- Co-targeted therapy involves the use of one or more therapeutics aimed at multiple targets, for example PI3K and MEK, in an attempt to generate a synergistic response and prevent the development of drug resistance. (wikipedia.org)
Carcinoma9
- This article will delineate the current data available from clinical trials investigating combined-modality therapy for locally advanced head and neck carcinoma. (cancernetwork.com)
- The Radiation Therapy Oncology Group (RTOG) conducted a randomized trial (RTOG 73-03) comparing preoperative 50 Gy to postoperative 60 Gy in 277 patients with locally advanced carcinoma of the supraglottis and hypopharynx. (cancernetwork.com)
- A randomized trial of thymosin fraction V (60 mg/m2 s.c. twice weekly) given during induction chemotherapy and radiation therapy was performed in 91 patients with small cell carcinoma of the lung. (nih.gov)
- I. To compare nivolumab following combined modality therapy (CMT) with observation in patients with high risk anal carcinoma with regard to objective response rate (complete [CR] and partial [PR]), stable disease and progression. (clinicaltrialsgps.com)
- To compare nivolumab following combined modality therapy (CMT) with observation in patients with high risk anal carcinoma with regard to severe toxicity interval. (clinicaltrialsgps.com)
- Both in a rodent (lung fibroblast) and a human solid tumour (lung carcinoma) cell line synergistic effects after combined exposures to ultrasound and radiation was found. (ki.se)
- Another drawback of available RCTs is combining 2 different biological cancer entities: adenocarcinoma and squamous cell carcinoma of the esophagus as well as carcinoma of the esophagus and gastro-esophageal junction. (knowcancer.com)
- [email protected]#To evaluate the efficacy of combined modality therapy for advanced hypopharyngeal carcinoma in order to improve the curative effect of hypopharyngeal carcinoma . (bvsalud.org)
- METHOD @#Seventy-six male patients with the stage III - IV hypopharyngeal carcinoma were treated with postoperative combined modality. (bvsalud.org)
Adjuvant2
- See also adjuvant therapy , neoadjuvant therapy, chemotherapy . (cancer.org)
- This article reviews the role of staging, surgery, and adjuvant and preoperative therapies in the management of localized gastric and esophageal cancers. (jnccn.org)
Drug Therapy1
- of immunosuppressive drug therapy . (hopkinsmedicine.org)
Malignancies2
- Lung cancer kills more Americans annually than the next four most frequently diagnosed malignancies combined. (elsevier.com)
- Purpose: Combined modality therapy is a mainstay option for thoracic malignancies and head and neck cancers. (elsevier.com)
Outcomes2
- The majority of patients with advanced rectal cancers who require external beam radiation therapy, extensive pelvic surgery, and intraoperative radiation therapy report unfavorable functional and quality-of-life outcomes after sphincter preservation. (nih.gov)
- By combining ADT with a higher dose of EBRT delivered with 3D-CRT or IMRT radiation therapy the outcomes of stage III patients have been improved. (yourcancercare.com)
Preoperative combined3
- The most frequent side-effect of the preoperative combined therapy was dermatitis (grade 3 in 19 patients). (springer.com)
- preoperative combined modality therapy and the matrix. (hopkinsmedicine.org)
- Forastiere, A.A. Phase II, parallel-design study of preoperative combined modality therapy and the matrix metalloprotease (mmp) inhibitor prinomastat in patients with esophageal adenocarcinoma. (hopkinsmedicine.org)
Cancer Therapies1
- Targeted cancer therapies are expected to be more effective than older forms of treatments and less harmful to normal cells. (wikipedia.org)
Versus1
- however, a direct comparison of trimodality therapy versus chemotherapy plus radiation has not been performed. (elsevier.com)
Rectal2
- Locally advanced primary and recurrent rectal cancers treated with external beam radiation therapy, intraoperative radiation therapy, and chemotherapy represent a complex group of patients in the setting of extensive pelvic surgery and sphincter preservation. (nih.gov)
- We retrospectively reviewed our experience with locally advanced primary and recurrent rectal cancer patients who underwent intraoperative radiation therapy with either low anterior resection (n = 12) or coloanal anastomosis (n = 6) between 1991 and 1998. (nih.gov)
Cancers1
- Regarding the use of IORT in colon cancer, NCCN guidelines state: "Intraoperative radiation therapy, if available, should be considered for patients with T4 or recurrent cancers as an additional boost. (aetna.com)
Tumors8
- For patients who present with large primary tumors or regional disease (American Joint Committee on Cancer stages III/IV), historical therapy has been surgery followed by postoperative radiation. (cancernetwork.com)
- If they are socially about a download combined modality therapy of central nervous system tumors, we will be them consider up a new Language so they can sustain their reflection in their My Digital Library or via our Other fair nights. (sierrasignsaz.com)
- No download combined modality therapy of central nervous system tumors art on the De Rerum Natura, as frankly and ed, is aloud immediately as this English writing in monitoring the emulsion of personal known bed in the work and language of the Roman. (sierrasignsaz.com)
- be you for your download combined modality therapy of central nervous system tumors. (sierrasignsaz.com)
- Methods: The Italian Association of Radiation Oncology Young Members Working Group (AIRO Giovani) organized its 8th national meeting, focused on combination therapy in lung, esophageal, and head and neck cancer (with a specific focus on larynx-preservation strategies for larynx/hypopharynx tumors), involving young professionals working in Italy. (elsevier.com)
- Radiation therapy uses radiation to kill cancer cells and shrink tumors. (epnet.com)
- Local iontophoretic administration of cytotoxic therapies to solid tumors. (unc.edu)
- Wharam, M. Pre-radiation chemotherapy with response-based radiation therapy in children with central nervous system germ cell tumors: a report from the Children''s Oncology Group. (hopkinsmedicine.org)
Pulmonary1
- Additional sequential lobar lavage and continued GM-CSF therapy as an outpatient resulted in complete resolution of oxygen requirement and return to normal pulmonary physiology. (biomedcentral.com)
Radiation Thera1
- The use of intensity-modulated radiation therapy (IMRT) is associated with fewer acute and late toxic effects than is three-dimensional conformal radiation therapy (3D-CRT) in men with localized prostate cancer, according to preliminary analysis of the Radiation Therapy Oncology Group (RTOG) 0126. (ascopost.com)
Surgical resection1
- Induction chemotherapy followed by radiation therapy is an acceptable alternative to surgical resection for organ preservation. (cancernetwork.com)
Treatments3
- The integration of different treatments in the clinical decision-making process to combine therapies is crucial. (elsevier.com)
- Salvage Local Treatments After Focal Therapy for Prostate Cancer. (bioportfolio.com)
- Whether focal therapy (FT) jeopardizes subsequent prostate cancer (PCa) salvage treatments, when needed, remains a major concern and is largely unknown. (bioportfolio.com)
Surgery5
- For patients with operable esophageal adenocarcinoma, combined-modality therapy should include surgery. (cancernetwork.com)
- Trimodality therapy (surgery plus radiation plus chemotherapy) with a variety of schedules also has been explored. (elsevier.com)
- Surgery was performed 4 to 10 weeks after completion of neoadjuvant therapy. (duke.edu)
- It is not yet known whether chemotherapy is effective in treating women who have undergone surgery and radiation therapy for relapsed breast cancer. (stanford.edu)
- A phase I study of Foscan-mediated photodynamic therapy and surgery in patients with mesothelioma. (upenn.edu)
Lymphoma1
- Combined modality therapy may prove of benefit for patients with AIDS-related primary CNS lymphoma. (knowcancer.com)
Diagnostic1
- No universally accepted diagnostic criteria, laboratory tests, imaging studies or other modalities definitively diagnose or exclude burning mouth syndrome (BMS). (medscape.com)
PCNSL1
- Nine PCNSL patients and 11 SCNSL patients underwent whole-brain radiation therapy with 4-MV photons. (fujita-hu.ac.jp)
Systemic2
- The objectives of the talk are to review the role of systemic therapy in locally advanced non-small cell and to review the role of combined-modality therapy in people with locally advanced non-small cell lung cancer. (coursera.org)
- Topotecan is active against NSCLC, can safely be combined with RT at effective systemic doses, and can be given by continuous infusion, making it an attractive study agent against locally advanced NSCLC. (elsevier.com)
Recurrence1
- Cancer Recurrence - Risk, Therapy , and Surveillance View. (hopkinsmedicine.org)
Stereotactic body radiation therapy1
- Dr. Lischalk specializes in proton therapy, intensity modulated radiation therapy, image guided radiation therapy, RapidArc®, CyberKnife® stereotactic body radiation therapy, and stereotactic radiosurgery. (medstarhealth.org)
Intraoperative radiati1
- The term "intraoperative radiation therapy" may also refer to intra-operative brachytherapy, the temporary or permanent implantation of radioactive seeds. (aetna.com)
Aggressive1
- The purpose of this study was to develop an aggressive locally advanced orthotopic prostate cancer model for assessing high-dose image-guided radiation therapy combined with biological agents. (elsevier.com)
Investigational1
- Any investigational agent other than antiretroviral agents available by therapy IND. (knowcancer.com)
Positron-Emission T2
- Carbon 11-choline positron emission tomography/computed tomography and palliative local therapy for castration-resistant prostate cancer. (bioportfolio.com)
- Carbon 11-choline positron emission tomography/computed tomography (11C-choline PET/CT) and subsequent local therapy for oligometastatic prostate cancer have been reported to be effective, but their e. (bioportfolio.com)
Descriptor1
- Combined Modality Therapy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Neoadjuvant therapy1
- CONCLUSION: Although the overall complete response rate and toxicity seems similar in both arms, this is the first multi-institutional study to establish a relatively high (28%) pCR rate after neoadjuvant therapy. (duke.edu)
Photodynamic therapy6
- A device for applying light in photodynamic therapy is arranged to apply light in a pattern corresponding to the configuration of the lesion to be treated. (google.com)
- The present invention relates to the field of photodynamic therapy. (google.com)
- Photodynamic therapy involves the application of light to abnormal tissues (referred to herein as "lesions") in or on the body of a human or other mammalian subject to cause regression of the lesion. (google.com)
- In vivo Optical Properties of Norman Canine Prostate at 732 nm Using Motexafin Lutetium-mediated Photodynamic Therapy. (upenn.edu)
- Photodynamic Therapy Creates Fluence Rate-dependent Gradients in the Intratumoral Spatial Distribution of Oxygen. (upenn.edu)
- Intraperitoneal photodynamic therapy for peritoneal carcinomatosis and sarcomatosis. (upenn.edu)
Lung5
- More Americans will die from lung cancer each year (approximately 159,480) than from colon, breast, pancreatic, and prostate cancer combined (approximately 158,630), the next most common causes of cancer death. (coursera.org)
- This lecture is going to be dealing with the combined-modality therapy for patients with locally advanced non-small cell lung cancer. (coursera.org)
- Better staging systems and definitions of biologic prognostic factors may help determine the optimal therapy for locally advanced non-small cell lung cancer patients. (elsevier.com)
- Blanke, C & Johnson, DH 1995, ' Combined modality therapy in non-small cell lung cancer ', Current Opinion in Oncology , vol. 7, no. 2, pp. 144-149. (elsevier.com)
- Surprisingly, less may be more when it comes to radiation therapy with concurrent chemotherapy for patients with stage III non-small cell lung cancer (NSCLC), according to an interim analysis of the r. (ascopost.com)
Ultrasound1
- Extensive histological sampling following focal therapy of clinically significant prostate cancer with high-intensity focused ultrasound. (bioportfolio.com)
Approaches2
- Present the most recent advances in cancer therapy and basic cancer research from a clinical and laboratory perspective, with an emphasis on new translational research approaches. (utsouthwestern.edu)
- In this thesis, new approaches to improve tumour therapy for patients with inoperable, radiation- and chemoresistant tumours were in focus. (ki.se)