Hair Preparations
Coloring Agents
Color
Computer Graphics
The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication. (1/3622)
The bystander effect (BSE) is an interesting and important property of the herpes thymidine kinase/ganciclovir (hTK/GCV) system of gene therapy for cancer. With the BSE, not only are the hTK expressing cells killed upon ganciclovir (GCV) exposure but also neighboring wild-type tumor cells. On testing a large number of tumor cell lines in vitro, a wide range of sensitivity to bystander killing was found. Since transfer of toxic GCV metabolites from hTK-modified to wild-type tumor cells via gap junctions (GJ) seemed to be a likely mechanism of the BSE, we tested GJ function in these various tumors with a dye transfer technique and pharmacological agents known to affect GJ communication. We confirmed that mixtures of tumor cell resistant to the BSE did not show dye transfer from cell to cell while bystander-sensitive tumor cells did. Dieldrin, a drug known to decrease GJ communication, diminished dye transfer and also inhibited the BSE. Forskolin, an upregulator of cAMP did increase GJ, but directly inhibited hTK and therefore its effect on BSE could not be determined. We conclude that these observations further support port the concept that functional GJ play an important role in the BSE and further suggest that pharmacological manipulation of GJ may influence the outcome of cancer therapy with hTK/GCV. (+info)Prion domain initiation of amyloid formation in vitro from native Ure2p. (2/3622)
The [URE3] non-Mendelian genetic element of Saccharomyces cerevisiae is an infectious protein (prion) form of Ure2p, a regulator of nitrogen catabolism. Here, synthetic Ure2p1-65 were shown to polymerize to form filaments 40 to 45 angstroms in diameter with more than 60 percent beta sheet. Ure2p1-65 specifically induced full-length native Ure2p to copolymerize under conditions where native Ure2p alone did not polymerize. Like Ure2p in extracts of [URE3] strains, these 180- to 220-angstrom-diameter filaments were protease resistant. The Ure2p1-65-Ure2p cofilaments could seed polymerization of native Ure2p to form thicker, less regular filaments. All filaments stained with Congo Red to produce the green birefringence typical of amyloid. This self-propagating amyloid formation can explain the properties of [URE3]. (+info)Purification and characterization of a novel peroxidase from Geotrichum candidum dec 1 involved in decolorization of dyes. (3/3622)
A peroxidase (DyP) involved in the decolorization of dyes and produced by the fungus strain Geotrichum candidum Dec 1 was purified. DyP, a glycoprotein, is glycosylated with N-acetylglucosamine and mannose (17%) and has a molecular mass of 60 kDa and an isoelectric point (pI) of 3.8. The absorption spectrum of DyP exhibited a Soret band at 406 nm corresponding to a hemoprotein, and its Na2S2O4-reduced form revealed a peak at 556 nm that indicates the presence of a protoheme as its prosthetic group. Nine of the 21 types of dyes that were decolorized by Dec 1 cells were decolorized by DyP; in particular, anthraquinone dyes were highly decolorized. DyP also oxidized 2,6-dimethoxyphenol and guaiacol but not veratryl alcohol. The optimal temperature for DyP activity was 30 degrees C, and DyP activity was stable even after incubation at 50 degrees C for 11 h. (+info)Identification of Epichloe endophytes in planta by a microsatellite-based PCR fingerprinting assay with automated analysis. (4/3622)
Epichloe endophytes are a group of filamentous fungi that include both sexual (Epichloe) and asexual (Neotyphodium) species. As a group they are genetically diverse and form both antagonistic and mutualistic associations with temperate grasses. We report here on the development of a microsatellite-based PCR system for fingerprinting this group of fungi with template isolated from either culture or infected plant material. M13mp19 partial genomic libraries were constructed for size-fractionated genomic DNA from two endophyte strains. These libraries were screened with a mixture of DIG-labeled dinucleotide and trinucleotide repeat probes. Positive clones were sequenced, and nine unique microsatellite loci were identified. An additional microsatellite was serendipitously identified in the 3' untranscribed region of the 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase gene from N. lolii Lp19. Primers were designed for each locus and a panel of endophytes, from different taxonomic groupings, was screened to determine the degree of polymorphism. On the basis of these results a multiplex assay was developed for strain identification with fluorescently labeled primers for five of these loci. Using this system the size of the products amplified can be precisely determined by automated analysis, and an allele profile for each strain can be readily generated. The assay was shown to resolve endophyte groupings to the level of known isozyme phenotype groupings. In a blind test the assay was used successfully to identify a set of endophytes in planta. A reference database of allele sizes has been established for the panel of endophytes examined, and this will be expanded as new strains are analyzed. (+info)An animal exposure system using ultrasonic nebulizer that generates well controlled aerosols from liquids. (5/3622)
Various aerosol generators have been developed for animal inhalation experiments and the performance tests of measuring instruments and respirators. It has been, however, difficult to generate aerosols from an aqueous solution or suspension keeping the concentration and particle size distribution constant for a long time. Resolving such difficulties, the present study developed an animal exposure system that generates well-controlled and stable aerosols from liquids. The exposure system consists of an aerosol generator using ultrasonic nebulizer, a mixing chamber and an exposure chamber. The validity of this system was confirmed in the generation of NiCl2 and TiO2 aerosol from solution and suspension, respectively. The concentration levels of NiCl2 aerosol were kept at 3.2 mg/m3 and 0.89 mg/m3 for 5 hours with good coefficients of variation (CVs) of 2.5% and 1.7%, respectively. For TiO2 aerosol, the concentration levels of 1.59 mg/m3 and 0.90 mg/m3 were kept for 5 hours with small CVs of 1.3% and 2.0%, respectively. This exposure system could be sufficiently used for inhalation experiments with even high toxic aerosols such as NiCl2 because a momentary high concentration possibly affects results and an extremely stable concentration is required. (+info)Psoriatic keratinocytes show reduced IRF-1 and STAT-1alpha activation in response to gamma-IFN. (6/3622)
Psoriasis is a chronic inflammatory dermatosis characterized by hyperproliferative keratinocytes (KC). The skin lesions are infiltrated by T cells, which secrete gamma interferon (gamma-IFN) and are believed to be necessary to maintain the psoriatic phenotype. In normal KC, gamma-IFN is a potent inhibitor of proliferation, but proliferation of KC persists in psoriatic plaques despite the presence of gamma-IFN. Immunostaining of interferon regulatory factor-1 (IRF-1) revealed that IRF-1 was localized to the basal cells of the epidermis in normal and in nonlesional psoriatic skin, but was suprabasal or completely absent in lesional psoriatic skin. This finding led to the hypothesis that abnormal signaling in the gamma-IFN pathway may occur in psoriatic KC. To test this hypothesis, we measured activation of IRF-1 and signal transducer and activator of transcription (STAT)-1alpha transcription factors in KC after stimulation with gamma-IFN. Primary cultures of KC from normal and nonlesional psoriatic skin were stimulated with gamma-IFN and subsequent transcription factor activation was measured by electrophoretic mobility shift assay. Psoriatic KC showed a reduced induction of IRF-1 and STAT-1alpha activation after stimulation with gamma-IFN, compared with normal KC. Reduced activation of IRF-1 and STAT-1alpha in response to gamma-IFN indicates a fundamental defect in the growth and differentiation control of psoriatic KC in the absence of the influence of other cell types. (+info)Heparin inhibits proliferation of myometrial and leiomyomal smooth muscle cells through the induction of alpha-smooth muscle actin, calponin h1 and p27. (7/3622)
Mast cells are widely distributed in human tissues, including the human uterus. However, the function of mast cells in uterine smooth muscle has not been clearly established. Mast cells possess secretory granules containing such substances as heparin, serotonin, histamine and many cytokines. To help establish the role of mast cells in the human myometrium, the action of heparin was investigated using smooth muscle cells (SMC) from normal myometrium and from leiomyoma. The proliferation of cultured myometrial and leiomyomal SMC was inhibited by heparin treatment. Flow cytometric analysis showed that the population in the G1 phase of the cell cycle increased under heparin treatment. Western blotting analysis showed that markers of SMC differentiation such as alpha-smooth muscle actin (alpha-SMA), calponin h1 and cyclin-dependent kinase inhibitor p27 were induced by heparin, whereas cell-cycle-related gene products from the G1 phase of the cell cycle, such as cyclin E and cdk2, were not changed. Taken together, these results indicate that heparin inhibits the proliferation of myometrial and leiomyomal SMC through the induction of alpha-SMA, calponin h1 and p27. We suggest that heparin from mast cells may induce differentiation in uterine SMC and may influence tissue remodelling and reconstruction during physiological and pathophysiological events. (+info)Detection of small numbers of immature cells in the blood of healthy subjects. (8/3622)
AIMS: To determine the frequency of immature haemopoietic cells in the peripheral blood of healthy persons. METHODS: Cytocentrifuge preparations were made using mononuclear leucocytes separated by a Ficoll-Hypaque density gradient. The slides were stained by May-Grunwald-Giemsa. The combination with immunoperoxidase technique allowed immunotyping of uncommon blood cells. RESULTS: Blast cells expressing the progenitor cell marker CD34 represented 0.11 (0.06) per cent (mean (SD)) of the total mononuclear leucocyte count; these were the haemopoietic progenitor cells in the peripheral blood. Dark blue cells expressing CD38, CD45, HLA-DR, CD4, CD11a, CD29, CD49d, CD50, and CD54 represented 0.30 (0.21) per cent of the mononuclear leucocytes; most of these cells did not express T, B, NK, myelomonocytic, progenitor cell, proliferation, activation, blood dendritic cell, or follicular dendritic cell markers. These were dendritic cell precursors in the peripheral blood. Very small numbers of cells expressing CD83 were found. Blast-like cells expressing CD45, HLA-DR, CD11a, and CD50 represented 0.15 (0.10) per cent of the mononuclear leucocytes; morphology and immunotyping supported the conclusion that these cells were poorly differentiated monocytes. CONCLUSIONS: Morphological investigation of mononuclear leucocytes in peripheral blood of healthy persons can be used to detect small numbers of blasts, dark blue cells, and blast-like cells. The immunoperoxidase technique can then be used for immunotyping of these cells. This simple method may be helpful in diagnosing haematological disorders. (+info)Curcumin is a natural yellow pigment that is derived from the turmeric plant (Curcuma longa). It has been used for centuries in traditional medicine for its anti-inflammatory, antioxidant, and anti-cancer properties. In the medical field, curcumin is being studied for its potential therapeutic effects in a variety of conditions, including: 1. Inflammation: Curcumin has been shown to have potent anti-inflammatory effects, making it a potential treatment for conditions such as rheumatoid arthritis, osteoarthritis, and inflammatory bowel disease. 2. Cancer: Curcumin has been shown to have anti-cancer properties, including the ability to inhibit the growth and spread of cancer cells. It is being studied as a potential treatment for a variety of cancers, including breast, prostate, and colon cancer. 3. Neurodegenerative diseases: Curcumin has been shown to have neuroprotective effects, making it a potential treatment for conditions such as Alzheimer's disease and Parkinson's disease. 4. Cardiovascular disease: Curcumin has been shown to have anti-atherosclerotic effects, making it a potential treatment for conditions such as coronary artery disease and stroke. 5. Diabetes: Curcumin has been shown to have anti-diabetic effects, making it a potential treatment for type 2 diabetes. While curcumin has shown promise in preclinical studies, more research is needed to determine its safety and efficacy in humans.
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WHO HQ Library catalog
Effect of staining agents on color change of composites
Wray Shows True Colors By Rewarding FBI Agent Who Pushed "Whitmer Kidnapping Plot" With Plum Promotion - Revolver News
Aluminum | Public Health Statement | ATSDR
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Skin of Color Underrepresented in Datasets Used by AI to Identify Skin Cancer
Reactive dye color fixing agent BS-RF Zhejiang Fine Chemical Technology Co., Ltd.
Chemical Burns: Background, Pathophysiology, Etiology
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Agent Orange affecting children and grandchildren of Vietnam Vets | WREG.com
Hepatitis D (Delta agent): MedlinePlus Medical Encyclopedia
VX: Nerve Agent | NIOSH | CDC
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
AGENT COALITION | Logo Design Contest | LogoTournament
Re: [whatwg] Icon mask and theme color from Anne van Kesteren on 2015-06-15 ([email protected] from June 2015)
Coloring Page US Capital - free printable coloring pages - Img 10367
Patching Chips And Small Holes In Granite | GSA
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Food and Drug Regulations
Inactive Ingredients / Excipients in Supplements - ConsumerLab.com
January 2005 - Spectra Colors
Farewell, and a final review of EPO Board of Appeal Decisions - The IPKat
Horse Bloodstock Agents in Benton Arkansas
Gay Collections | Gay | Bold Strokes Books
These Were the 5 Most Popular Real Estate Stories on Apartment Therapy This Year | Apartment Therapy
Buy Gluvit Waterproof Epoxy Sealer 2 Pound Kit RM330KC in Canada Binnacle.com
Amber-colored1
- Clear, amber-colored, oily liquid. (cdc.gov)
Oily liquid1
- How might I be exposed to nerve agents GA, odorless, oily liquid. (cdc.gov)
20231
- Federal law enforcement agents executed a search warrant and served a federal grand jury subpoena to WWE Executive Chairman Vince McMahon last month, July 2023, according to a regulatory filing. (kdvr.com)
Substances2
- The aim of this study was to evaluate, in vitro, the color changing of composites after immersion in different substances for different periods. (bvsalud.org)
- Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. (bvsalud.org)
Nerve agents14
- VX is one of the nerve agents, which are the most toxic of the known chemical warfare agents. (cdc.gov)
- Nerve agents are chemically similar to organophosphate pesticides and exert their effects by interfering with the normal function of the nervous system. (cdc.gov)
- This fact sheet answers the most frequently asked health questions (FAQs) about nerve agents. (cdc.gov)
- HIGHLIGHTS: Exposure to nerve agents can occur due to accidental release from a military storage facility. (cdc.gov)
- Nerve agents are highly toxic regardless of the route of exposure. (cdc.gov)
- The United States no longer produces nerve agents GA, Most of the nerve agents were originally produced in a GB, GD, and VX. (cdc.gov)
- Nerve agents have been agents GA, GB, GD, or VX unless there is an accidental used in wars and by terrorists. (cdc.gov)
- People who work at military sites where these compounds are stored may be potentially exposed to nerve agents GA, What happens to nerve agents GA, GB, GD, and GB, GD, and VX. (cdc.gov)
- Even in very small amounts, nerve agents are highly toxic if down by compounds that are found in the air, but they may you inhale or swallow them, or if they come in contact with persist in air for a few days before being broken down. (cdc.gov)
- ToxFAQsTM Internet address is http://www.atsdr.cdc.gov/toxfaq.html effects is faster if you inhale or swallow nerve agents than if know whether children differ from adults in their they contact your skin. (cdc.gov)
- The initial effects also depend on susceptibility to nerve agents. (cdc.gov)
- We do not know if exposure to the nerve agents GA, GB, long as 18 hours. (cdc.gov)
- It is unlikely that the general population will be exposed to defecation and urination, muscle twitching, confusion, nerve agents. (cdc.gov)
- There are medical tests available to determine whether you persist for as long as 6 weeks after recovery from an have been exposed to nerve agents. (cdc.gov)
Dosage1
- Accurate dosage depend on dyed material color. (water-treatmentchemical.com)
Shades2
- I remember looking around the playground and not seeing colors, only seeing the trees and sky in different shades of gray. (michigandaily.com)
- Do you need to see the tiniest details on your screen, identify shades of colors, or just make working on your computer more comfortable on your eyes? (microsoft.com)
Exposure3
- Rice wanted veterans to put pressure on Congress to pass a military toxic exposure bill so scientists can study the generational effects of Agent Orange. (wreg.com)
- The report presents general considerations and guidance on the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives, including flavouring agents. (who.int)
- The Committee identifies and, if possible, quantifies the public health significance of exposure to chemicals in food - in these cases, food additives including flavouring agents - through scientific risk assessment based on international consensus. (who.int)
Illustrations1
- Discover a magical world of creativity with these enchanting and whimsical illustrations perfect for relaxation Hocus Pocus Coloring Pages Bring your favorite bewitching characters to life, unleashing your inner artist and immersing yourself in spellbinding fun. (coloring-pages.net)
Describe2
- Despite the high profile nature of the case, D'Antuono's agents couldn't describe any detailed plan for the kidnapping the men were supposedly plotting. (revolver.news)
- Puce is a particularly difficult color to describe. (cdc.gov)
Closely2
- Your real estate agent will have to closely work with the seller, so he or she will likely know why the seller wants to list the home. (bekins.com)
- have been recognized in the United States: human monocytic ehrlichiosis (HME), caused by E. chaffeensis, and human granulocytic ehrlichiosis (HGE), caused by an agent closely related to E. equi (1,2). (cdc.gov)
Solvents1
- Specifications for identity and purity of carrier solvents, emulsifiers and stabilizers, enzyme preparations, flavouring agents, food colours, sweetening agents and other food additives / as prepared by the 25th session of the Joint FAO/WHO Expert Committee on Food Additives, Geneva, 23 March to 1 April 1981. (who.int)
Health1
- The military later admitted Agent Orange caused cancer and other health problems for vets. (wreg.com)
Clear2
- Your agent will give you a realistic number for all of these costs so you have a clear understanding about whether you can afford your new home. (bekins.com)
- The G-type agents are clear, quickly. (cdc.gov)
Differ1
- Color filters change the color palette on the screen and can help you distinguish between things that differ only by color. (microsoft.com)
Real estate agents4
- One of the biggest mistakes new real estate agents make is trying to design their own real estate website. (webene.com)
- It is vital to set yourself apart from other real estate agents, to do this you need a brand. (webene.com)
- It's easy as a real estate agent to become generic because most real estate agents seem to rely on the schtick of the happy family in front of their new home with a sold sign in the background. (webene.com)
- The services are provided by real estate agents of the coalition, who are at different firms, collaborating together for clients. (logotournament.com)
Change5
- You'll also find instructions on how to change to a high contrast theme to reduce the white background color on the screen. (microsoft.com)
- Whenever you change the color and contrast options, check the apps and features you use the most to see how they look with the new settings. (microsoft.com)
- Learn how to change color and contrast on your computer to make things easier to see and read on the screen. (microsoft.com)
- Your screen colors will change as you make a selection. (microsoft.com)
- A confirmed case of HGE was defined as either a fourfold change in antibody titer to E. equi or identification of DNA sequences of the HGE agent by PCR assay. (cdc.gov)
Image1
- A) Digitally colored scanning electron microscopic image of a flea. (cdc.gov)
Assessment1
- For the assessment of staining, a spectrophotometer for colorimetry was used (Color Guide 45 / 0, PCB 6807 BYK-Gardner Gerestsried GmBH, Germany), and the values obtained were transferred to a computer and recorded according to CIELAB system. (bvsalud.org)
Food1
- Specifications for identity and purity of food colours, flavouring agents and other food additives / as prepared by the 23rd session of the Joint FAO/WHO Expert Committee on Food Additives, Geneva, 2-11 April 1979. (who.int)
Time4
- Your agent should be able to estimate this date by the time you close or put money in your escrow account. (bekins.com)
- With all the other responsibilities of being a real estate agent, website design is not one that should take up all your time. (webene.com)
- To find the color and contrast settings that work for you, first think about what you do on your computer most of the time and which apps you use during the day. (microsoft.com)
- The severity of the burn is related to a number of factors, including the pH of the agent, the concentration of the agent, the length of the contact time, the volume of the offending agent, and the physical form of the agent. (medscape.com)
Make4
- There are key features that can make your real estate agent website drive business towards you as a real estate agent. (webene.com)
- In this article, you'll find tips and tricks on how to experiment with the color options on your computer and in the Microsoft 365 apps to make it easier and more comfortable for you to see the things on your screen. (microsoft.com)
- You'll also learn how to modify the colors and contrast in Microsoft 365 apps to make them more accessible. (microsoft.com)
- For example, the Inverted option reverses the colors on your display and might make working in most apps more comfortable. (microsoft.com)
Show1
- It changes the color temperature of your screen which will show warmer colors that are easier on your eyes. (microsoft.com)
Case2
- His most prestigious case by far climaxed just last week, as it was D'Antuono's agents who helped arrest 13 men for allegedly plotting to kidnap Michigan governor Gretchen Whitmer. (revolver.news)
- An FBI agent testified Thursday in the Jose Padilla terrorism case how members of an alleged Islamic extremist support network used code to disguise their conversations, substituting words like "tourism" and "football" for "jihad. (jpost.com)
Things3
- In addition to these important things, you shouldn't forget to ask your real estate agent the following questions. (bekins.com)
- This article will outline a few of the things our professionals are mindful of when developing successful real estate agent websites. (webene.com)
- Don't worry, you can always go back to the original color and contrast settings if you don't like how things look on your screen. (microsoft.com)
Filter1
- Whether you have light sensitivity, a visual preference, or it's hard to see and read what's on the screen, try applying a color filter. (microsoft.com)
Material1
- Product Brief: KM-ICB0007 6 Can cooler bag Size: 22.5*15*14CM Color: Blue Material: Nylon with PP webbing shoulder strap. (ecvv.com)
Property1
- Including Legal, Agent & Broker, and Property Rights Issues. (nar.realtor)
Understand1
- We sat on the floor of the airport (they did not offer us chairs), under the imperious gaze of a self-proclaimed Homeland Security agent (didn't he understand that this was my homeland, too? (michigandaily.com)
Orange6
- WREG uncovered how decades after the Vietnam war, veterans exposed to Agent Orange are still fighting for disability pension payments. (wreg.com)
- Agent Orange didn't just manifest in the bloodstream of veterans. (wreg.com)
- She was born without a uterus and they're saying some of the children were from Agent Orange," said Mary Smith the spouse of Vietnam Veteran. (wreg.com)
- Smith was among the crowd of parents and grandparents wanting to know if their children and grandchildren inherited the legacy of Agent Orange. (wreg.com)
- He's held 10 of these Agent Orange meetings in a year to encourage vets to get Congress involved. (wreg.com)
- Doctors diagnosed and linked Rice's Non-Hodgkin`s lymphoma directly to Agent Orange. (wreg.com)
Website1
- Let our real estate website developers work with you to create a tagline that's unique to who you are as a real estate agent. (webene.com)
Found1
- Found 645 promotion bag Sourcing Services , promotion bag Manufacturers and Sourcing Agent. (ecvv.com)
Phone1
- The agent, John T. Kavanaugh, said participants suspected they were being overheard by government officials and urged each other not to openly discuss sensitive matters over the phone. (jpost.com)
Find1
- How do I find the best color and contrast settings for me? (microsoft.com)
Logo1
- AGENT COALITION has selected their winning logo design. (logotournament.com)
White1
- After a summer of riots and revolutionary activities by Antifa and BLM, FBI director Wray claimed that "white supremacist" terrorism is the biggest threat to America's well-being, followed by Russian agents. (revolver.news)
Chemical2
Process1
- 4. Powdered flavors and colors are produced through a spray drying process in the spray dry room. (cdc.gov)