Sacs or reservoirs created to function in place of the COLON and/or RECTUM in patients who have undergone restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
The part of the face that is below the eye and to the side of the nose and mouth.
Tumors or cancer of the COLON.
A surgical procedure involving the excision of the COLON and RECTUM and the formation of an ILEOANAL RESERVOIR (pouch). In patients with intestinal diseases, such as ulcerative colitis, this procedure avoids the need for an OSTOMY by allowing for transanal defecation.
A sac or recess formed by a fold of the peritoneum.
Acute INFLAMMATION in the INTESTINAL MUCOSA of the continent ileal reservoir (or pouch) in patients who have undergone ILEOSTOMY and restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.
Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
A genus of the family Muridae having three species. The present domesticated strains were developed from individuals brought from Syria. They are widely used in biomedical research.
The motor activity of the GASTROINTESTINAL TRACT.
A family of herbivorous leaping MAMMALS of Australia, New Guinea, and adjacent islands. Members include kangaroos, wallabies, quokkas, and wallaroos.
Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.
Functional obstruction of the COLON leading to MEGACOLON in the absence of obvious COLONIC DISEASES or mechanical obstruction. When this condition is acquired, acute, and coexisting with another medical condition (trauma, surgery, serious injuries or illness, or medication), it is called Ogilvie's syndrome.
Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.
A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.
The normal process of elimination of fecal material from the RECTUM.

Similar outcome after colonic pouch and side-to-end anastomosis in low anterior resection for rectal cancer: a prospective randomized trial. (1/75)

OBJECTIVES: To compare a colonic J-pouch or a side-to-end anastomosis after low-anterior resection for rectal cancer with regard to functional and surgical outcome. SUMMARY BACKGROUND DATA: A complication after restorative rectal surgery with a straight anastomosis is low-anterior resection syndrome with a postoperatively deteriorated anorectal function. The colonic J-reservoir is sometimes used with the purpose of reducing these symptoms. An alternative method is to use a simple side-to-end anastomosis. METHODS: One-hundred patients with rectal cancer undergoing total mesorectal excision and colo-anal anastomosis were randomized to receive either a colonic pouch or a side-to-end anastomosis using the descending colon. Surgical results and complications were recorded. Patients were followed with a functional evaluation at 6 and 12 months postoperatively. RESULTS: Fifty patients were randomized to each group. Patient characteristics in both groups were very similar regarding age, gender, tumor level, and Dukes' stages. A large proportion of the patients received short-term preoperative radiotherapy (78%). There was no significant difference in surgical outcome between the 2 techniques with respect to anastomotic height (4 cm), perioperative blood loss (500 ml), hospital stay (11 days), postoperative complications, reoperations or pelvic sepsis rates. Comparing functional results in the 2 study groups, only the ability to evacuate the bowel in <15 minutes at 6 months reached a significant difference in favor of the pouch procedure. CONCLUSIONS: The data from this study show that either a colonic J-pouch or a side-to-end anastomosis performed on the descending colon in low-anterior resection with total mesorectal excision are methods that can be used with similar expected functional and surgical results.  (+info)

Long-term functional results after ileal pouch anal restorative proctocolectomy for ulcerative colitis: a prospective observational study. (2/75)

OBJECTIVE: To document functional results in patients treated with an ileal pouch anal anastomosis (IPAA). SUMMARY BACKGROUND DATA: The restorative proctocolectomy with IPAA has become the procedure of choice for patients with ulcerative colitis, yet the long-term functional results are not well known. METHODS: We performed this prospective observational study in 391 consecutive patients (56% male; mean age, 33.7 +/- 10.8 years; range, 12-66 years) who underwent an IPAA between 1987 and 2002 (mean follow-up, 33.6 months; range, 0 to 180 months). RESULTS: The majority of patients underwent the procedure under elective circumstances with a hand-sewn ileal pouch anal anastomosis and a protective ileostomy. In 25 patients (6.4%), the procedure was performed under urgent conditions; in 137 patients (35%), the temporary ileostomy was omitted; in 117 patients (29.9%), the ileal pouch anal anastomosis was stapled. There was 1 hospital mortality (0.25%) and 1 30-day mortality. Mean length of stay was 9.2 +/- 5.6 days (3-68 days; median, 8 days) and was increased by the occurrence of septic complications (8.9 versus 13.6 days; P < 0.02) and by the omission of a temporary ileostomy (8.3 versus 10.4 days; P = 0.005). Complications included pelvic abscess (1.3%), anastomotic dehiscence (6.4%), bowel obstruction (11.7%), and anastomotic stenosis in need of mechanical dilatation (10.7%). Patients were asked to record their functional results on a questionnaire for 1 week at 3, 6, 9, 12, 18, and 24 months after the IPAA and yearly thereafter. Our data to 10 years show that median number of bowel movements (bms) was 6 bm/24 hours at all time intervals. The average number of bms increased by 0.3 bm/decade of life (P < 0.001). Throughout the entire follow-up, more than 75% of patients had at least 1 bm most nights, although fewer than 40% found it necessary to alter the time of their meals to avoid bms at inappropriate times. Depending on the time interval, between 57% and 78% of patients were always able to postpone a bm until convenient, and this ability was similar in patients with a stapled or hand-sewn ileoanal anastomosis; only up to 18% were able to always distinguish between flatus and stools, and this ability was similar in patients with a stapled or hand-sewn ileoanal anastomosis. Complete daytime and nighttime continence was achieved by 53-76% of patients depending on the time interval. The percentage of fully continent patients was higher following the stapled rather than the hand-sewn technique (P < 0.001), and this difference persisted over time. When patients experienced incontinence, its occurrence ameliorated over time (P < 0.001), and the occurrence of perianal rash and itching as well as the use of protective pads decreased over time (P < 0.008). At 5 years, patients judged quality of life as much better or better in 81.4% and overall satisfaction and overall adjustment as excellent or good in 96.3% and 97.5%, respectively. CONCLUSIONS: We conclude that the IPAA confers a good quality of life. The majority of patients are fully continent, have 6 bms/d on average, and can defer a bm until convenient. When present, incontinence improves over time.  (+info)

Training in trauma surgery: quantitative and qualitative aspects of a new paradigm for fellowship. (3/75)

OBJECTIVE: To describe outcomes from a clinical trauma surgical education program that places the board-eligible/board-certified fellow in the role of the attending surgeon (fellow-in-exception [FIE]) during the latter half of a 2-year trauma/surgical critical care fellowship. SUMMARY BACKGROUND DATA: National discussions have begun to explore the question of optimal methods for postresidency training in surgery. Few objective studies are available to evaluate current training models. METHODS: We analyzed provider-specific data from both our trauma registry and performance improvement (PI) databases. In addition, we performed TRISS analysis when all data were available. Registry and PI data were analyzed as 2 groups (faculty trauma surgeons and FIEs) to determine experience, safety, and trends in errors. We also surveyed graduate fellows using a questionnaire that evaluated perceptions of training and experience on a 6-point Likert scale. RESULTS: During a 4-year period 7,769 trauma patients were evaluated, of which 46.3% met criteria to be submitted to the PA Trauma Outcome Study (PTOS, ie, more severe injury). The faculty group saw 5,885 patients (2,720 PTOS); the FIE group saw 1,884 patients (879 PTOS). The groups were similar in respect to mechanism of injury (74% blunt; 26% penetrating both groups) and injury severity (mean ISS faculty 10.0; FIEs 9.5). When indexed to patient contacts, FIEs did more operations than the faculty group (28.4% versus 25.6%; P < 0.05). Death rates were similar between groups (faculty 10.5%; FIEs 10.0%). Analysis of deaths using PI and TRISS data failed to demonstrate differences between the groups. Analysis of provider-specific errors demonstrated a slightly higher rate for FIEs when compared with faculty when indexed to PTOS cases (4.1% versus 2.1%; P < 0.01). For both groups, errors in management were more common than errors in technique. Twenty-one (91%) of twenty-three surveys were returned. Fellows' feelings of preparedness to manage complex trauma patients improved during the fellowship (mean 3.2 prior to fellowship versus 4.5 after first year versus 5.8 after FIE year; P < 0.05 by ANOVA). Eighty percent rated the FIE educational experience "great -5" or "exceptional- 6." Eighty-five percent consider the current structure of the fellowship (with FIE year) as ideal. Ninety percent would repeat the fellowship. CONCLUSION: The educational experience and training improvement offered by the inclusion of a FIE period during a trauma fellowship is exceptional. Patient outcomes are unchanged. The potential for an increased error rate is present during this period of clinical autonomy and must be addressed when designing the methods of supervision of care to assure concurrent senior staff review.  (+info)

Quantification of risk for pouch failure after ileal pouch anal anastomosis surgery. (4/75)

OBJECTIVE: To identify risk factors associated with ileal pouch failure and to develop a multifactorial model for quantifying the risk of failure in individual patients. SUMMARY BACKGROUND DATA Ileal pouch anal anastomosis (IPAA) has become the treatment choice for most patients with ulcerative colitis and familial adenomatous polyposis who require surgery. At present, there are no published studies that investigate collectively the interrelation of factors related to ileal pouch failure, nor are there any predictive indices for risk stratification of patients undergoing IPAA surgery. METHODS: Data from 23 preoperative, 7 intraoperative, and 10 postoperative risk factors were recorded from 1,965 patients undergoing restorative proctocolectomy in a single center between 1983 and 2001. Primary end point was ileal pouch failure during the follow-up period of up to 19 years. The "CCF ileal pouch failure" model was developed using a parametric survival analysis and a 70%:30% split-sample validation technique for model training and testing. RESULTS: The median patient follow-up was 4.1 year (range, 0-19 years). Five-year ileal pouch survival was 95.6% (95% CI, 94.4-96.7). The following risk factors were found to be independent predictors of pouch survival and were used in the final multivariate model: patient diagnosis, prior anal pathology, abnormal anal manometry, patient comorbidity, pouch-perineal or pouch-vaginal fistulae, pelvic sepsis, anastomotic stricture and separation. The model accurately predicted the risk of ileal pouch failure with adequate calibration statistics (Hosmer Lemeshow chi2 = 3.001; P = 0.557) and an area under the receiver operating characteristics curve of 82.0%. CONCLUSIONS: The CCF ileal pouch failure model is a simple and accurate way of predicting the risk of ileal pouch failure in clinical practice on a longitudinal basis. It may play an important role in providing risk estimates for patients wishing to make informed choices on the type of treatment offered to them.  (+info)

Short- and long-term outcomes of ileal pouch-anal anastomosis for ulcerative colitis. (5/75)

Ileal pouch-anal anastomosis was an important advancement in the treatment of ulcerative colitis. The aim of this study was to determine whether early complications of ileal pouch-anal anastomosis in patients with ulcerative colitis are associated with poor late functional results. PATIENTS AND METHODS: Eighty patients were operated on from 1986 to 2000, 62 patients with ileostomy and 18 without. The early and late complications were recorded. Specific emphasis has been placed on the incidence of pouchitis with prolonged follow-up. RESULTS: The ileostomy was closed an average of 9.2 months after the first operation. Fourteen patients were excluded from the long-term evaluation; 6 patients were lost to regular follow-up, 4 died, and 4 patients still have the ileostomy. Of the 4 patients that died, 1 died from surgical complications. Early complications after operation (41) occurred in 34 patients (42.5%). Late complications (29) occurred in 25 patients as follows: 16 had pouchitis, 3 associated with stenosis and 1 with sexual dysfunction; 5 had stenosis; and there was 1 case each of incisional hernia, ileoanal fistula, hepatic cancer, and endometriosis. Pouchitis occurred in 6 patients (9.8%) 1 year after ileal pouch-anal anastomosis, 9 (14.8%) after 3 years, 13 (21.3%) after 5 years, and 16 (26.2%) after more than 6 years. The mean daily stool frequency was 12 before and 5.8 after operation. One pouch was removed because of fistulas that appeared 2 years later. CONCLUSIONS: Ileal pouch-anal anastomosis is associated with a considerable number of early complications. There was no correlation between pouchitis and severe disease, operation with or without ileostomy, or early postoperative complications. The incidence of pouchitis was directly proportional to duration of time of follow-up.  (+info)

Could laparoscopic colon and rectal surgery become the standard of care? A review and experience with 750 procedures. (6/75)

INTRODUCTION: The benefits of the laparoscopic approach to colon and rectal surgery do not seem as great as for other laparoscopic procedures. To study this further we decided to review the current literature and the 10-year experience of a surgical group from university teaching hospitals in Montreal, Quebec and Toronto in performing laparoscopic colon and rectal surgery. METHODS: The prospectively designed case series comprised all patients having laparoscopic colon and rectal surgery. The procedures were carried out by a group of 4 surgeons between April 1991 and November 2001. We noted intraoperative complications, any conversions to open surgery, operating time, postoperative complications and postoperative length of hospital stay. RESULTS: The group attempted 750 laparoscopic colon and rectal procedures of which 669 were completed laparoscopically. Malignant disease was the indication for surgery in 49.6% of cases. Right hemicolectomy and sigmoid colectomy accounted for 54.5% of procedures performed. Intraoperative complications occurred in 8.3%, with 29.0% of these resulting in conversion to open surgery. The overall rate of conversion to open surgery was 10.8%, most commonly for oncologic concerns. Median operating time was 175 minutes for all procedures. Postoperative complications occurred in 27.5% of procedures completed laparoscopically but were mostly minor wound complications. Pulmonary complications occurred in only 1.0%. The anastomotic leak rate was 2.5%. The early reoperation rate was 2.4%. Postoperative mortality was 2.2%. No port site metastases have yet been detected. The median postoperative length of stay was 5 days. CONCLUSIONS: The clinical outcomes of laparoscopic colon and rectal surgery in this 10-year experience are consistent with numerous cohort studies and randomized clinical trials. Laparoscopic colon and rectal surgery in the hands of well-trained surgeons can be performed safely with short hospital stay, low analgesic requirements and acceptable complication rates compared with historical controls and other reports in the literature. Evidence from published randomized clinical trials is emerging that under these conditions laparoscopic resection represents the better treatment option for most benign conditions, but concerns regarding its appropriateness for malignant disease are still to be resolved.  (+info)

Continent diversions: the new gold standards of ileoanal reservoir and neobladder. (7/75)

In recent decades, surgical treatment of familial adenomatous polyposis, chronic ulcerative colitis, and muscle-invasive bladder cancer has undergone a revolution. Specifically, ileoanal reservoir and neobladder have become the new "gold standard" of definitive surgical therapy for these disorders. This article discusses issues in surgical construction, indications, contraindications, perioperative care concepts, and nursing and health professional implications related to these two procedures. These interventions include screening candidates for ileoanal reservoir or neobladder to rule out Crohn's disease or metastatic cancer and educating candidates for continent diversions about the proposed procedure(s) and associated events, potential complications, postoperative exercise, sexual health and function issues, and the benefits of support group participation so they can gain a realistic understanding of ultimate functional outcomes. Questions for future research are addressed.  (+info)

The effect of ageing on function and quality of life in ileal pouch patients: a single cohort experience of 409 patients with chronic ulcerative colitis. (8/75)

OBJECTIVE: To evaluate in what manner ageing affects functional outcome and quality of life (QoL) in patients with chronic ulcerative colitis (CUC) after ileal pouch-anal anastomosis (IPAA). SUMMARY BACKGROUND DATA: Short-term function and QoL after IPAA is good. However, patients are usually young, and little is known about the influence of time and ageing on long-term outcomes after IPAA. METHODS: Using a standardized questionnaire, functional outcome, QoL, and complications were assessed prospectively in a cohort of 409 patients followed annually for 15 years after IPAA. RESULTS: Follow-up was complete in the single cohort of 409 patients and functional and QoL outcomes summarized at 5, 10, and 15 years. Daytime stool frequency changed little (mean 6), while nighttime frequency increased from 1 stool to 2 stools. Incontinence for gas and stool increased from 1% to 10% during the day and from 2% to 24% at night over 15 years. The cumulative probability of pouchitis increased from 28% at 5 years to 38% at 10 years and to 47% at 15 years. Bowel obstruction and stricture were other principal long-term complications. At 15 years, 91% of patients had kept the same job. Work was not affected by the surgery in 83%, while social activities, sports, traveling, and sexual life all improved after surgery and did not deteriorate over time. CONCLUSIONS: These long-term results in a single cohort of 409 IPAA patients are unique and are likely a more accurate reflection of long-term outcome than has been previously reported. These data support the conclusion that IPAA is a durable operation for patients requiring proctocolectomy for CUC; functional and QoL outcomes are good, predictable, and stable for 15 years after operation.  (+info)

Colonic pouches, also known as pouch colon or reservoir, refer to an artificial structure created during a surgical procedure called restorative proctocolectomy. This is often performed in patients with certain types of inflammatory bowel disease like ulcerative colitis or familial adenomatous polyposis.

During the surgery, the entire colon and rectum are removed. A pouch is then created using the patient's own small intestine, which is folded back on itself and sewn together to form a reservoir. This pouch is connected to the anus, allowing the patient to have relatively normal bowel movements.

The most common type of colonic pouch is the J-pouch, so named because of its J-shaped design. Other types include the S-pouch and the W-pouch. The choice of pouch depends on various factors, including the patient's anatomy and the surgeon's preference.

The purpose of creating a colonic pouch is to restore intestinal continuity and function after removing the diseased colon and rectum, thereby improving the patient's quality of life. However, it's important to note that living with a colonic pouch also requires significant lifestyle adjustments and ongoing medical management.

The colon, also known as the large intestine, is a part of the digestive system in humans and other vertebrates. It is an organ that eliminates waste from the body and is located between the small intestine and the rectum. The main function of the colon is to absorb water and electrolytes from digested food, forming and storing feces until they are eliminated through the anus.

The colon is divided into several regions, including the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum, and anus. The walls of the colon contain a layer of muscle that helps to move waste material through the organ by a process called peristalsis.

The inner surface of the colon is lined with mucous membrane, which secretes mucus to lubricate the passage of feces. The colon also contains a large population of bacteria, known as the gut microbiota, which play an important role in digestion and immunity.

Colonic diseases refer to a group of medical conditions that affect the colon, also known as the large intestine or large bowel. The colon is the final segment of the digestive system, responsible for absorbing water and electrolytes, and storing and eliminating waste products.

Some common colonic diseases include:

1. Inflammatory bowel disease (IBD): This includes conditions such as Crohn's disease and ulcerative colitis, which cause inflammation and irritation in the lining of the digestive tract.
2. Diverticular disease: This occurs when small pouches called diverticula form in the walls of the colon, leading to symptoms such as abdominal pain, bloating, and changes in bowel movements.
3. Colorectal cancer: This is a type of cancer that develops in the colon or rectum, often starting as benign polyps that grow and become malignant over time.
4. Irritable bowel syndrome (IBS): This is a functional gastrointestinal disorder characterized by abdominal pain, bloating, and changes in bowel movements, but without any underlying structural or inflammatory causes.
5. Constipation: This is a common condition characterized by infrequent bowel movements, difficulty passing stools, or both.
6. Infectious colitis: This occurs when the colon becomes infected with bacteria, viruses, or parasites, leading to symptoms such as diarrhea, abdominal cramps, and fever.

Treatment for colonic diseases varies depending on the specific condition and its severity. Treatment options may include medications, lifestyle changes, surgery, or a combination of these approaches.

A "cheek" is the fleshy, muscular area of the face that forms the side of the face below the eye and above the jaw. It contains the buccinator muscle, which helps with chewing by moving food to the back teeth for grinding and also assists in speaking and forming facial expressions. The cheek also contains several sensory receptors that allow us to perceive touch, temperature, and pain in this area of the face. Additionally, there is a mucous membrane lining inside the mouth cavity called the buccal mucosa which covers the inner surface of the cheek.

Colonic neoplasms refer to abnormal growths in the large intestine, also known as the colon. These growths can be benign (non-cancerous) or malignant (cancerous). The two most common types of colonic neoplasms are adenomas and carcinomas.

Adenomas are benign tumors that can develop into cancer over time if left untreated. They are often found during routine colonoscopies and can be removed during the procedure.

Carcinomas, on the other hand, are malignant tumors that invade surrounding tissues and can spread to other parts of the body. Colorectal cancer is the third leading cause of cancer-related deaths in the United States, and colonic neoplasms are a significant risk factor for developing this type of cancer.

Regular screenings for colonic neoplasms are recommended for individuals over the age of 50 or those with a family history of colorectal cancer or other risk factors. Early detection and removal of colonic neoplasms can significantly reduce the risk of developing colorectal cancer.

Restorative proctocolectomy, also known as ileal pouch-anal anastomosis (IPAA), is a surgical procedure used to treat ulcerative colitis and familial adenomatous polyposis. This procedure involves the removal of the colon, rectum, and anal canal while preserving the sphincter muscles that control fecal continence.

After removing the diseased tissues, the surgeon creates a pouch from the end of the small intestine (ileum) and attaches it to the anus, restoring the continuity of the gastrointestinal tract. The pouch serves as a reservoir for stool, allowing for more normal bowel movements compared to having a permanent ileostomy.

Restorative proctocolectomy can be performed in one or two stages, depending on the patient's condition and the surgeon's preference. In the two-stage procedure, an initial total colectomy with ileostomy is performed, followed by the creation of the pouch and closure of the ileostomy in a second operation. The single-stage procedure involves removing the colon, creating the pouch, and performing the anastomosis in one surgical setting.

While restorative proctocolectomy significantly improves quality of life for many patients with ulcerative colitis and familial adenomatous polyposis, potential complications include pouchitis (inflammation of the ileal pouch), anastomotic leakage, small bowel obstruction, and pelvic sepsis. Regular follow-up care is essential to monitor for these and other potential issues.

The Douglas pouch, also known as the recto-uterine pouch or cul-de-sac of Douglas, is a potential space within the female pelvic cavity. It is located between the posterior wall of the uterus and the anterior wall of the rectum. This space can be examined during a gynecological examination, such as a transvaginal ultrasound or during surgery, to assess for any abnormalities or pathologies that may be present in this area.

Pouchitis is a condition characterized by inflammation of the ileal pouch, a surgically created reservoir that is connected to the patient's anus in individuals who have undergone proctocolectomy with ileal pouch-anal anastomosis (IPAA). This procedure is often performed in patients with ulcerative colitis or familial adenomatous polyposis.

Pouchitis can present with symptoms such as diarrhea, abdominal cramps, urgency, and fecal incontinence. The exact cause of pouchitis remains unclear, but it is thought to be related to changes in the microbiota or an overactive immune response in the ileal pouch.

The diagnosis of pouchitis typically involves a combination of clinical symptoms, endoscopic findings, and histopathological examination of biopsies taken during endoscopy. Treatment options for pouchitis include antibiotics, anti-inflammatory medications, and probiotics, depending on the severity and frequency of the condition.

The intestinal mucosa is the innermost layer of the intestines, which comes into direct contact with digested food and microbes. It is a specialized epithelial tissue that plays crucial roles in nutrient absorption, barrier function, and immune defense. The intestinal mucosa is composed of several cell types, including absorptive enterocytes, mucus-secreting goblet cells, hormone-producing enteroendocrine cells, and immune cells such as lymphocytes and macrophages.

The surface of the intestinal mucosa is covered by a single layer of epithelial cells, which are joined together by tight junctions to form a protective barrier against harmful substances and microorganisms. This barrier also allows for the selective absorption of nutrients into the bloodstream. The intestinal mucosa also contains numerous lymphoid follicles, known as Peyer's patches, which are involved in immune surveillance and defense against pathogens.

In addition to its role in absorption and immunity, the intestinal mucosa is also capable of producing hormones that regulate digestion and metabolism. Dysfunction of the intestinal mucosa can lead to various gastrointestinal disorders, such as inflammatory bowel disease, celiac disease, and food allergies.

Colonic polyps are abnormal growths that protrude from the inner wall of the colon (large intestine). They can vary in size, shape, and number. Most colonic polyps are benign, meaning they are not cancerous. However, some types of polyps, such as adenomas, have a higher risk of becoming cancerous over time if left untreated.

Colonic polyps often do not cause any symptoms, especially if they are small. Larger polyps may lead to symptoms like rectal bleeding, changes in bowel habits, abdominal pain, or iron deficiency anemia. The exact cause of colonic polyps is not known, but factors such as age, family history, and certain medical conditions (like inflammatory bowel disease) can increase the risk of developing them.

Regular screening exams, such as colonoscopies, are recommended for individuals over the age of 50 to detect and remove polyps before they become cancerous. If you have a family history of colonic polyps or colorectal cancer, your doctor may recommend earlier or more frequent screenings.

Ulcerative colitis is a type of inflammatory bowel disease (IBD) that affects the lining of the large intestine (colon) and rectum. In ulcerative colitis, the lining of the colon becomes inflamed and develops ulcers or open sores that produce pus and mucous. The symptoms of ulcerative colitis include diarrhea, abdominal pain, and rectal bleeding.

The exact cause of ulcerative colitis is not known, but it is thought to be related to an abnormal immune response in which the body's immune system attacks the cells in the digestive tract. The inflammation can be triggered by environmental factors such as diet, stress, and infections.

Ulcerative colitis is a chronic condition that can cause symptoms ranging from mild to severe. It can also lead to complications such as anemia, malnutrition, and colon cancer. There is no cure for ulcerative colitis, but treatment options such as medications, lifestyle changes, and surgery can help manage the symptoms and prevent complications.

Colitis is a medical term that refers to inflammation of the inner lining of the colon or large intestine. The condition can cause symptoms such as diarrhea, abdominal cramps, and urgency to have a bowel movement. Colitis can be caused by a variety of factors, including infections, inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), microscopic colitis, ischemic colitis, and radiation therapy. The specific symptoms and treatment options for colitis may vary depending on the underlying cause.

"Mesocricetus" is a genus of rodents, more commonly known as hamsters. It includes several species of hamsters that are native to various parts of Europe and Asia. The best-known member of this genus is the Syrian hamster, also known as the golden hamster or Mesocricetus auratus, which is a popular pet due to its small size and relatively easy care. These hamsters are burrowing animals and are typically solitary in the wild.

Gastrointestinal motility refers to the coordinated muscular contractions and relaxations that propel food, digestive enzymes, and waste products through the gastrointestinal tract. This process involves the movement of food from the mouth through the esophagus into the stomach, where it is mixed with digestive enzymes and acids to break down food particles.

The contents are then emptied into the small intestine, where nutrients are absorbed, and the remaining waste products are moved into the large intestine for further absorption of water and electrolytes and eventual elimination through the rectum and anus.

Gastrointestinal motility is controlled by a complex interplay between the autonomic nervous system, hormones, and local reflexes. Abnormalities in gastrointestinal motility can lead to various symptoms such as bloating, abdominal pain, nausea, vomiting, diarrhea, or constipation.

Macropodidae is not a medical term, but a taxonomic family in the order Diprotodontia, which includes large marsupials commonly known as kangaroos, wallabies, and tree-kangaroos. These animals are native to Australia and New Guinea. They are characterized by their strong hind legs, large feet adapted for leaping, and a long muscular tail used for balance. Some members of this family, particularly the larger kangaroo species, can pose a risk to humans in certain situations, such as vehicle collisions or aggressive encounters during breeding season. However, they are not typically associated with medical conditions or human health.

Gastrointestinal transit refers to the movement of food, digestive secretions, and waste products through the gastrointestinal tract, from the mouth to the anus. This process involves several muscles and nerves that work together to propel the contents through the stomach, small intestine, large intestine, and rectum.

The transit time can vary depending on factors such as the type and amount of food consumed, hydration levels, and overall health. Abnormalities in gastrointestinal transit can lead to various conditions, including constipation, diarrhea, and malabsorption. Therefore, maintaining normal gastrointestinal transit is essential for proper digestion, nutrient absorption, and overall health.

Colonic pseudo-obstruction, also known as Ogilvie's syndrome, is a medical condition characterized by the absence of an actual physical obstruction in the colon, but with symptoms and radiologic findings that mimic a mechanical intestinal obstruction. It is caused by a dysfunction of the nervous system or muscles in the colon, leading to severe dilation and potential perforation if not treated promptly.

The condition is often associated with underlying medical conditions such as surgery, trauma, infection, electrolyte imbalances, neurologic disorders, and certain medications. The symptoms may include abdominal pain, distention, nausea, vomiting, constipation, and in severe cases, fever and sepsis.

Treatment typically involves decompression of the colon using a nasogastric tube or colonoscopy, as well as addressing any underlying causes. In some cases, surgery may be necessary to remove the excess gas and stool from the colon or to repair a perforation.

An ileostomy is a surgical procedure in which the end of the small intestine, called the ileum, is brought through an opening in the abdominal wall (stoma) to create a path for waste material to leave the body. This procedure is typically performed when there is damage or removal of the colon, rectum, or anal canal due to conditions such as inflammatory bowel disease (Crohn's disease or ulcerative colitis), cancer, or trauma.

After an ileostomy, waste material from the small intestine exits the body through the stoma and collects in a pouch worn outside the body. The patient needs to empty the pouch regularly, typically every few hours, as the output is liquid or semi-liquid. Ileostomies can be temporary or permanent, depending on the underlying condition and the planned course of treatment. Proper care and management of the stoma and pouch are essential for maintaining good health and quality of life after an ileostomy.

Diverticulosis, colonic is a medical condition characterized by the presence of small sacs or pouches (diverticula) that form on the outer wall of the large intestine (colon). These sacs are usually found in the sigmoid colon, which is the part of the colon that is closest to the rectum.

Diverticulosis occurs when the inner layer of the colon's muscle pushes through weak spots in the outer layer of the colon wall, creating small pockets or sacs. The exact cause of diverticulosis is not known, but it may be associated with a low-fiber diet, aging, and increased pressure in the colon.

Most people with diverticulosis do not experience any symptoms, and the condition is often discovered during routine screening exams or when complications arise. However, some people may experience cramping, bloating, and changes in bowel habits.

Diverticulosis can lead to complications such as inflammation (diverticulitis), bleeding, and infection. It is important to seek medical attention if you experience symptoms such as severe abdominal pain, fever, or rectal bleeding, as these may be signs of a more serious condition.

Treatment for diverticulosis typically involves making dietary changes, increasing fiber intake, and taking medications to manage symptoms. In some cases, surgery may be necessary to remove affected portions of the colon.

Defecation is the medical term for the act of passing stools (feces) through the anus. It is a normal bodily function that involves the contraction of muscles in the colon and anal sphincter to release waste from the body. Defecation is usually a regular and daily occurrence, with the frequency varying from person to person.

The stool is made up of undigested food, bacteria, and other waste products that are eliminated from the body through the rectum and anus. The process of defecation is controlled by the autonomic nervous system, which regulates involuntary bodily functions such as heart rate and digestion.

Difficulties with defecation can occur due to various medical conditions, including constipation, irritable bowel syndrome, and inflammatory bowel disease. These conditions can cause symptoms such as hard or painful stools, straining during bowel movements, and a feeling of incomplete evacuation. If you are experiencing any problems with defecation, it is important to speak with your healthcare provider for proper diagnosis and treatment.

  • OBJECTIVE: This study aimed to assess quality of life and bowel function in patients who underwent colonic J-pouch or straight colorectal anastomosis reconstruction after low anterior resection. (unipd.it)
  • PATIENTS: Patients who underwent low anterior resection for primary mid-low rectal cancer and who were randomly assigned in a 1:1 ratio to receive either stapled colonic J-pouch or straight colorectal anastomosis were selected. (unipd.it)
  • Also known as iIeal pouch anal anastomosis. (hollister.com)
  • What Is an Ileoanal Anastomosis (J-Pouch) Surgery? (hdkino.org)
  • An ileal pouch-anal anastomosis (J-pouch) is a surgical procedure to restore the stomach and bowel (gastrointestinal) continuity after the surgical removal of the large bowel (the colon and rectum). (hdkino.org)
  • An ileal pouch-anal anastomosis (J-pouch) surgery treats the stomach and bowel. (hdkino.org)
  • The Ileoanal anastomosis (J-pouch) is often protected by temporarily diverting the path of stool through a temporary opening on the abdomen ( ileostomy ). (hdkino.org)
  • Who needs an Ileoanal anastomosis (J-pouch) surgery? (hdkino.org)
  • The following will help you understand what to expect during an ileal pouch-anal anastomosis (J-pouch) surgery. (hdkino.org)
  • Benign diseases - Inflammatory bowel diseases (IBD) - surgical procedures such as Total proctocolectomy with ileal pouch anal anastomosis. (ap.nic.in)
  • Restorative proctocolectomy (RPC) with ileal J-pouch-anal anastomosis (IPAA) has become the procedure of choice for most patients who require colectomy because of ulcerative colitis or familial adenomatous polyposis. (mssm.edu)
  • After total abdominal colectomy, 68 patients went on to ileal pouch anal anastomosis by either a two-stage or three-stage approach. (childrensmercy.org)
  • CONCLUSIONS: In the children studied, 13% had a diagnostic change to Crohn's disease, and 13% were diagnosed with Crohn's after ileal pouch-anal anastomosis (IPAA). (childrensmercy.org)
  • Surgeons most often perform a proctocolectomy with ileal pouch anal anastomosis, although very ill patients may receive lesser procedures, including proctocolectomy with ileostomy or even total abdominal colectomy with ileostomy, leaving the rectal stump behind in the pelvis. (medscape.com)
  • E. Proctocolectomy and ileal pouch-anal canal anastomosis. (latestinterviewquestions.com)
  • C. Despite complete removal of the colon and rectum, transanal fecal flow can be preserved by means of an ileal pouch-anal anastomosis. (latestinterviewquestions.com)
  • The preferred surgical procedure for UC is restorative proctocolectomy with ileum pouch and anal anastomosis. (greek.doctor)
  • A restorative pouch was created after colectomy in 46% using a two-stage approach while, 53% were managed with an initial colectomy and three-stage approach. (childrensmercy.org)
  • C. Colectomy and continent ileostomy (Kock pouch). (latestinterviewquestions.com)
  • These are outpockets of the colonic mucosa and submucosa through weaknesses of muscle layers in the colon wall. (wikipedia.org)
  • Diverticulosis is the condition of having multiple pouches (diverticula) in the colon that are not inflamed. (wikipedia.org)
  • After the colon is removed, the small intestine is used to create a reservoir pouch that is placed in the pelvis and connected to the anus. (hollister.com)
  • The J-pouch surgery is performed after the large bowel (the colon and rectum) has been completely removed. (hdkino.org)
  • A condition marked by small sacs or pouches (diverticula) in the walls of an organ such as the stomach or colon. (icd9data.com)
  • And although it's an intriguing concept, there is no firm data that the sitting position causes colonic diverticulosis (pouches in the wall of the colon). (org.in)
  • Because water is normally absorbed from the colonic content, principally in the ascending, or right, colon, diarrhea can be caused by any inflammatory, neoplastic, or vascular disturbance of that part of the colon. (britannica.com)
  • Hi, Colonic inertia is a condition in which the nerves and/or muscles of the colon do not work normally. (medhelp.org)
  • A pouch or sac opening from the colon . (lookfordiagnosis.com)
  • We report a case of persistent cloaca and type I congenital pouch colon associated with ileovesical and colovesical fistulae. (jiaps.com)
  • Congenital pouch colon (CPC) is a complex anorectal malformation (ARM). (jiaps.com)
  • The ileum was separated from the pouch colon and the urinary bladder. (jiaps.com)
  • Pouch colon syndrome' or CPC is a severe type of anorectal malformation. (jiaps.com)
  • [1] The important characteristics of CPC are its association with ARM, presence of a pouch colon, malrotation, abnormal vascular supply of CPC, absence of appendices epiploicae, and haustrations on the CPC, and a big muscular fistula with the urogenital system, along with gross vesicoureteral reflux. (jiaps.com)
  • However, in our case the entire normal colon was replaced by a pouch. (jiaps.com)
  • Colonic diverticulosis is the presence of one or more diverticula in the colon. (msdmanuals.com)
  • Infected pouches along the colon. (epnet.com)
  • Kolonics or Colonics (often called colon cleansing or colon irrigation) is a procedure where purified warm water is allowed to pass thoroughly and slowly into the colon (large intestine) for cleansing. (superbhub.com)
  • Colon Hydrotherapy also is known as (Kolonics) colonics , Colonic Irrigation, High Enema and Colon Therapy. (superbhub.com)
  • The cecum, which is the proximal blind end (pouch) of the ascending (right) colon, is a blind cul-de-sac below the level of the ileocecal junction that lies in the right iliac fossa. (medscape.com)
  • The large intestine, especially the colon, is covered with numerous omental appendages (appendices epiploicae)-appendages of fat, each containing a vessel of its own from the colonic wall. (medscape.com)
  • Restorative total proctocolectomy with J-pouch is a procedure used for children with severe ulcerative colitis or premalignant conditions like familial polyposis. (psu.edu)
  • Laparoscopic Total/Subtotal - Colectomies - IBD, Multicentric malignancies Restorative Pouch Surgeries - Lap. (aadicura.com)
  • Restorative Pouch Surgeries - Lap. (aadicura.com)
  • He introduced a popular modification to the technique for creating an ileo-anal pouch , or j-pouch for ulcerative colitis, in which double stapling is used in place of sutures to improve results. (wikipedia.org)
  • CONCLUSION: The findings of this study do not support the routine use of colonic J-pouch reconstruction in patients with rectal cancer who undergo a low anterior resection. (unipd.it)
  • He also popularized the colonic j-pouch for patients with rectal cancer. (wikipedia.org)
  • Resection of the rectum and total excision of the internal anal sphincter with smooth muscle plasty and colonic pouch for treatment of ultralow rectal carcinoma. (journal-imab-bg.org)
  • I have been told that regular colonic hydration is good for cleaning out the diverticula in a person with diverticulosis. (medhelp.org)
  • Definition of Diverticular Disease Diverticula are saclike mucosal pouches that protrude from a tubular structure. (msdmanuals.com)
  • People who have colonic diverticulosis usually have several diverticula. (msdmanuals.com)
  • Most people with colonic diverticulosis are unaware of this structural change. (wikipedia.org)
  • The etiology of colonic diverticulosis is multifactorial and not entirely known. (msdmanuals.com)
  • Although all are potentially quite serious, guidelines are set up specifically to monitor for colonic dysplasia. (medscape.com)
  • A finding indicating the presence of multiple pouches, usually in the colonic or gastric wall. (icd9data.com)
  • Our case was of type I classification (as there was no appendix, and the cecum and ileum were followed by the pouch) according to Rao et al . (jiaps.com)
  • Its critical function is to limit the reflux of colonic contents into the ileum. (uz-gnesin-academy.ru)
  • An artificial rectum (the ileum pouch) is created by using loops of ileum to serve as a reservoir for faeces, which is then anastomosed with the anus. (greek.doctor)
  • Additionally, fellows spend time with other members of the Cedars-Sinai teaching staff, gaining valuable insights into enterostomal care, anorectal and colonic physiologic testing, anorectal ultrasound and pelvic floor disorders. (cedars-sinai.edu)
  • In addition to the usual complications of abdomino-pelvic surgery, there are other complications more specific to this procedure: pouchitis, pouch ischemia, fistula, and anastomotic leaks (leading potential to pelvic sepsis or abscess). (mssm.edu)
  • The J-pouch, an alternative to a permanent ileostomy or colostomy, allows patients who have had their colons removed to continue to have regular bowel movements without an ostomy bag. (wikipedia.org)
  • The procedure involves the creation of a pouch of the small bowel to recreate the removed rectum (the part of the large bowel above the anus). (hdkino.org)
  • Some of the causes of colonic inertia include inadequate water intake, inadequate fiber, lack of physical activity, increased stress, hypothyroidism, eating large amounts of dairy products, irritable bowel syndrome, neurological diseases and depression. (medhelp.org)
  • Total proctocolectomy and ileal-anal pouch surgery is the removal of the large intestine and most of the rectum. (medlineplus.gov)
  • Anterior to the rectum is the rectovesical pouch in males and the rectouterine pouch in females. (medscape.com)
  • The cecum or caecum is a pouch within the peritoneum that is considered to be the beginning of the large intestine. (uz-gnesin-academy.ru)
  • Cecum: This first section of your large intestine looks like a pouch, about two inches long. (uz-gnesin-academy.ru)
  • I am 50 years old and my surgeons which i have seen 2 and my family doctor say i have a classic case of colonic inertia. (medhelp.org)
  • This problem happens when the small pouches tear or become blocked by stool. (epnet.com)
  • The pouch was also disconnected from the urinary bladder. (jiaps.com)
  • These are small pouches that can form in the wall of the large intestine. (epnet.com)
  • Then your surgeon will make a pouch out of the last 12 inches (30 centimeters) of your small intestine. (medlineplus.gov)
  • Type of skin barrier flange found on Hollister two-piece pouching systems that allows you to put your fingers under the skin barrier flange while attaching the pouch. (hollister.com)

No images available that match "colonic pouches"