Tumors or cancer of the COLON.
Hydrazines substituted with two methyl groups in any position.
Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.
A benign epithelial tumor with a glandular organization.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Neoplasms containing cyst-like formations or producing mucin or serum.
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Tumors or cancer of the SKIN.
Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.
Functional obstruction of the COLON leading to MEGACOLON in the absence of obvious COLONIC DISEASES or mechanical obstruction. When this condition is acquired, acute, and coexisting with another medical condition (trauma, surgery, serious injuries or illness, or medication), it is called Ogilvie's syndrome.
A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.
Tumors or cancers of the KIDNEY.
The motor activity of the GASTROINTESTINAL TRACT.
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

Classification of human colorectal adenocarcinoma cell lines. (1/11349)

Eleven human colorectal adenocarcinoma cell lines established in this laboratory were classified into three groups based on morphological features (light and electron microscopy), modal chromosome number, and ability to synthesize carcinoembryonic antigen (CEA). Group 1 cell lines contained both dedifferentiated and differentiating cells growing in tight clusters or islands of epithelium-like cells; their modal chromosome number was about 47, and they synthesized small to moderate amounts of CEA. Group 2 cell lines were more dedifferentiated, were hyperdiploid, and synthesized small amounts of CEA. Group 3 cell lines were morphologically similar to those of Group 1 by light microscopy. They differed ultrastructurally by containing microvesicular bodies; the modal chromosome number varied from hyperdiploid to hypertriploid or they had bimodal populations of hypodiploid and hypertriploid cells, and they synthesized relatively large amounts of CEA. No correlation could be found between Broder's grade or Duke's classification of the original tumor and modal chromosome number or ability to synthesize CEA. These findings support Nowell's hypothesis that the stem line is different for each solid tumor, which makes it difficult to relate chromosomal changes to the initiation of the neoplastic state.  (+info)

PKCdelta acts as a growth and tumor suppressor in rat colonic epithelial cells. (2/11349)

We have analysed the expression of three calcium-independent isoforms of protein kinase C (PKC), PKCdelta, PKCepsilon and PKCzeta, in an in vitro model of colon carcinogenesis consisting of the nontumorigenic rat colonic epithelial cell line D/WT, and a derivative src-transformed line D/src. While PKCzeta and PKCepsilon showed similar protein levels, PKCdelta was markedly decreased in D/src cells when compared to the D/WT line. To assess whether down-regulation of PKCdelta was causally involved in the neoplastic phenotype in D/src cells, we prepared a kinase-defective mutant of PKCdelta. Stable transfection of this sequence caused morphological and growth changes characteristic of partial transformation in D/WT cells. Moreover, to test whether PKCdelta was involved in growth control and transformation in this model, we overexpressed PKCdelta in D/src cells. Transfected cells underwent marked growth and morphological modifications toward the D/WT phenotype. In a late stage in culture, transfected cells ceased to proliferate, rounded up and degenerated into multinucleated, giant-like cells. We conclude that PKCdelta can reverse the transformed phenotype and act as a suppressor of cell growth in D/src cells. Moreover, our data show that downregulation of this isoenzyme of PKC may cooperate in the neoplastic transformation induced by the src oncogene in D/WT cells.  (+info)

The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells. (3/11349)

The acquisition of invasiveness is a crucial step in the malignant progression of cancer. In cancers of the colon and of other organs the E-cadherin/catenin complex, which is implicated in homotypic cell-cell adhesion as well as in signal transduction, serves as a powerful inhibitor of invasion. We show here that one allele of the alphaE-catenin (CTNNA1) gene is mutated in the human colon cancer cell family HCT-8, which is identical to HCT-15, DLD-1 and HRT-18. Genetic instability, due to mutations in the HMSH6 (also called GTBP) mismatch repair gene, results in the spontaneous occurrence of invasive variants, all carrying either a mutation or exon skipping in the second alphaE-catenin allele. The alphaE-catenin gene is therefore, an invasion-suppressor gene in accordance with the two-hit model of Knudsen for tumour-suppressor genes.  (+info)

Mechanisms related to [18F]fluorodeoxyglucose uptake of human colon cancers transplanted in nude mice. (4/11349)

[18F]Fluorodeoxyglucose ([18F]FDG), a glucose analogue, has been widely used for tumor imaging. To investigate the mechanisms related to [18F]FDG uptake by tumors, an experiment involving nude mice was performed. METHODS: Human colon cancer cell lines SNU-C2A, SNU-C4 and SNU-C5 were transplanted to nude mice. Using immunohistochemical staining and Western blot, the expression of glucose transporter (Glut) isoforms (Glut-1 through -5) in xenografted tumors was analyzed. For the analysis of messenger ribonucleic acid (mRNA) expression, reverse-transcription polymerase chain reaction and Northern blot were used and the enzyme activity of hexokinase in cancer tissues was measured by continuous spectrophotometric rate determination. RESULTS: [18F]FDG uptake in SNU-C4 and SNU-C5 cells was higher than in normal colon cells. Among these cells and xenografted tumors, SNU-C5 showed the highest level of [18F]FDG uptake, followed by SNU-C4 and SNU-C2A. An immunostaining experiment showed intense staining of Glut-1 in SNU-C5 tumors but somewhat faint staining in SNU-C4. SNU-C5 tumors also showed positive staining with Glut-3, although this was not the case with SNU-C2A and SNU-C4. Western blot analysis showed the expression of Glut-1 and Glut-3 in all tumors. Experiments involving Northern blot analysis and reverse-transcription polymerase chain reaction confirmed the overexpression of Glut-1 mRNA in all tumors, with the highest level in SNU-C5. The level of Glut-3 mRNA was also elevated in SNU-C5 tumors but not in SNU-C2A and SNU-C4. The enzyme activity of hexokinase did not vary among different tumors. CONCLUSION: Gluts, especially Glut-1, are responsible for [18F]FDG uptake in a nude mouse model of colon cancer rather than hexokinase activity. Increased numbers of glucose transporters at the plasma membrane of cancer cells is attributed to an increased level of transcripts of glucose transporter genes and may be a cause of increased [18F]FDG uptake, at least in colon cancer tumors.  (+info)

In vivo isolated kidney perfusion with tumour necrosis factor alpha (TNF-alpha) in tumour-bearing rats. (5/11349)

Isolated perfusion of the extremities with high-dose tumour necrosis factor alpha (TNF-alpha) plus melphalan leads to dramatic tumour response in patients with irresectable soft tissue sarcoma or multiple melanoma in transit metastases. We developed in vivo isolated organ perfusion models to determine whether similar tumour responses in solid organ tumours can be obtained with this regimen. Here, we describe the technique of isolated kidney perfusion. We studied the feasibility of a perfusion with TNF-alpha and assessed its anti-tumour effects in tumour models differing in tumour vasculature. The maximal tolerated dose (MTD) proved to be only 1 microg TNF-alpha. Higher doses appeared to induce renal failure and a secondary cytokine release with fatal respiratory and septic shock-like symptoms. In vitro, the combination of TNF-alpha and melphalan did not result in a synergistic growth-inhibiting effect on CC 531 colon adenocarcinoma cells, whereas an additive effect was observed on osteosarcoma ROS-1 cells. In vivo isolated kidney perfusion, with TNF-alpha alone or in combination with melphalan, did not result in a significant anti-tumour response in either tumour model in a subrenal capsule assay. We conclude that, because of the susceptibility of the kidney to perfusion with TNF-alpha, the minimal threshold concentration of TNF-alpha to exert its anti-tumour effects was not reached. The applicability of TNF-alpha in isolated kidney perfusion for human tumours seems, therefore, questionable.  (+info)

Cancer risk in close relatives of women with early-onset breast cancer--a population-based incidence study. (6/11349)

Inherited susceptibility to breast cancer is associated with an early onset and bilateral disease. The extent of familial risks has not, however, been fully assessed in population-based incidence studies. The purpose of the study was to quantify the risks for cancers of the breast, ovary and other sites of close relatives of women in whom breast cancer was diagnosed at an early age. Records collected between 1943 and 1990 at the Danish Cancer Registry were searched, and 2860 women were found in whom breast cancer was diagnosed before age 40. Population registers and parish records were used to identify 14 973 parents, siblings and offspring of these women. Cancer occurrence through to 31 December 1993 was determined within the Cancer Registry's files and compared with national incidence rates. Women with early-onset breast cancer were at a nearly fourfold increased risk of developing a new cancer later in life (268 observed vs. 68.9 expected). The excess risk was most evident for second cancer of the breast (181 vs. 24.5) and for ovarian cancer (20 vs. 3.3). For mothers and sisters, risks for cancers of the breast and ovary were significantly increased by two- to threefold. Bilateral breast cancer and breast-ovarian cancer were very strong predictors of familial risks, with one in four female relatives predicted to develop breast and/or ovarian cancer by age 75. Mothers had a slightly increased risk of colon cancer, but not endometrial cancer. The risk for breast cancer was also increased among fathers (standardized incidence ratio 2.5; 95% CI 0.5-7.4) and especially brothers (29; 7.7-74), although based on small numbers. The risk for prostatic cancer was unremarkable. In this large population-based survey, the first-degree relatives of women who developed breast cancer before age 40 were prone to ovarian cancer as well as male and female breast cancer, but not other tumours that may share susceptibility genes with breast cancer.  (+info)

Bombesin stimulates adhesion, spreading, lamellipodia formation, and proliferation in the human colon carcinoma Isreco1 cell line. (7/11349)

The neuropeptide bombesin and its mammalian homologue, gastrin-releasing peptide (GRP), enhance proliferation in some but not all human tumor cell lines. The pathophysiological relevance of the bombesin/GRP receptor (GRP-R), which is expressed in 30% of human colon tumor cell lines and in 24-40% of native tumors, has not been clearly assessed at this time. We studied the effects of bombesin in the recently characterized human colon carcinoma Isreco1 cell line. Competitive reverse transcription-PCR showed a high GRP-R mRNA level in Isreco1 cells, and binding studies confirmed the expression of bombesin/GRP-subtype receptors (Kd = 0.42 nM; Bmax = 18,000 sites/cell). Exposure to bombesin resulted in an increase of intracellular calcium concentrations. Bombesin (1 nM) induced cell spreading at 24 h (21.7+/-1.6% versus 6.4+/-0.8% in control cells; P<0.01) and markedly increased the formation of lamellipodia. In addition, adhesion of Isreco1 cells to collagen I-coated culture dishes was stimulated in the presence of 1 nM bombesin (69+/-6% versus 42+/-1% in control cells; P<0.01). Finally, bombesin significantly increased [3H]thymidine uptake by Isreco1 cells in a dose-dependent manner, with a first significant response at 0.1 nM and a maximal effect at 100 nM bombesin (192.2+/-9.7% of control). These results clearly indicate that bombesin exerts morphological, adhesive, and proliferative effects on Isreco1 cells, suggesting that expression of the bombesin/GRP-R may contribute to the malignant properties of colon carcinoma cells.  (+info)

Telomeric repeats on small polydisperse circular DNA (spcDNA) and genomic instability. (8/11349)

Small polydisperse circular DNA (spcDNA) is a heterogeneous population of extrachromosomal circular molecules present in a large variety of eukaryotic cells. Elevated amounts of total spcDNA are related to endogenous and induced genomic instability in rodent and human cells. We suggested spcDNA as a novel marker for genomic instability, and speculated that spcDNA might serve as a mutator. In this study, we examine the presence of telomeric sequences on spcDNA. We report for the first time the appearance of telomeric repeats in spcDNA molecules (tel-spcDNA) in rodent and human cells. Restriction enzyme analysis indicates that tel-spcDNA molecules harbor mostly, if not exclusively, telomeric repeats. In rodent cells, tel-spcDNA levels are higher in transformed than in normal cells and are enhanced by treatment with carcinogen. Tel-spcDNA is also detected in some human tumors and cell lines, but not in others. We suggest, that its levels in human cells may be primarily related to the amount of the chromosomal telomeric sequences. Tel-spcDNA may serve as a unique mutator, through specific mechanisms related to the telomeric repeats, which distinguish it from the total heterogeneous spcDNA population. It may affect telomere dynamics and genomic instability by clastogenic events, alterations of telomere size and sequestration of telomeric proteins.  (+info)

Colonic neoplasms refer to abnormal growths in the large intestine, also known as the colon. These growths can be benign (non-cancerous) or malignant (cancerous). The two most common types of colonic neoplasms are adenomas and carcinomas.

Adenomas are benign tumors that can develop into cancer over time if left untreated. They are often found during routine colonoscopies and can be removed during the procedure.

Carcinomas, on the other hand, are malignant tumors that invade surrounding tissues and can spread to other parts of the body. Colorectal cancer is the third leading cause of cancer-related deaths in the United States, and colonic neoplasms are a significant risk factor for developing this type of cancer.

Regular screenings for colonic neoplasms are recommended for individuals over the age of 50 or those with a family history of colorectal cancer or other risk factors. Early detection and removal of colonic neoplasms can significantly reduce the risk of developing colorectal cancer.

Dimethylhydrazines are organic compounds that consist of two methyl groups (-CH3) bonded to a hydrazine molecule (N2H4). The most common dimethylhydrazine is 1,2-dimethylhydrazine, which is a colorless liquid with an unpleasant odor. It is used as a rocket fuel and in the synthesis of other chemicals.

Dimethylhydrazines are highly reactive and can be hazardous to handle. They can cause skin and eye irritation, and prolonged exposure can lead to more serious health effects such as damage to the respiratory system, liver, and kidneys. Ingestion or inhalation of large amounts of dimethylhydrazines can be fatal.

It is important to handle dimethylhydrazines with care and follow proper safety precautions when working with them. This may include wearing protective clothing, gloves, and eye protection, as well as using appropriate ventilation and storage methods.

Intestinal polyps are abnormal growths that protrude from the lining of the intestines. They can occur in any part of the digestive tract, including the colon and rectum (colorectal polyps), small intestine, or stomach. These growths vary in size, shape, and number. Most intestinal polyps are benign, meaning they are not cancerous. However, some types of polyps, such as adenomatous polyps, can become cancerous over time if left untreated.

Intestinal polyps can be asymptomatic or cause symptoms like rectal bleeding, abdominal pain, changes in bowel habits, or anemia (in cases where there is chronic, slow bleeding). The exact cause of intestinal polyps is not fully understood, but factors such as age, family history, and certain genetic conditions can increase the risk of developing them. Regular screening exams, like colonoscopies, are essential for early detection and removal of polyps to prevent potential complications, including colorectal cancer.

An adenoma is a benign (noncancerous) tumor that develops from glandular epithelial cells. These types of cells are responsible for producing and releasing fluids, such as hormones or digestive enzymes, into the surrounding tissues. Adenomas can occur in various organs and glands throughout the body, including the thyroid, pituitary, adrenal, and digestive systems.

Depending on their location, adenomas may cause different symptoms or remain asymptomatic. Some common examples of adenomas include:

1. Colorectal adenoma (also known as a polyp): These growths occur in the lining of the colon or rectum and can develop into colorectal cancer if left untreated. Regular screenings, such as colonoscopies, are essential for early detection and removal of these polyps.
2. Thyroid adenoma: This type of adenoma affects the thyroid gland and may result in an overproduction or underproduction of hormones, leading to conditions like hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid).
3. Pituitary adenoma: These growths occur in the pituitary gland, which is located at the base of the brain and controls various hormonal functions. Depending on their size and location, pituitary adenomas can cause vision problems, headaches, or hormonal imbalances that affect growth, reproduction, and metabolism.
4. Liver adenoma: These rare benign tumors develop in the liver and may not cause any symptoms unless they become large enough to press on surrounding organs or structures. In some cases, liver adenomas can rupture and cause internal bleeding.
5. Adrenal adenoma: These growths occur in the adrenal glands, which are located above the kidneys and produce hormones that regulate stress responses, metabolism, and blood pressure. Most adrenal adenomas are nonfunctioning, meaning they do not secrete excess hormones. However, functioning adrenal adenomas can lead to conditions like Cushing's syndrome or Conn's syndrome, depending on the type of hormone being overproduced.

It is essential to monitor and manage benign tumors like adenomas to prevent potential complications, such as rupture, bleeding, or hormonal imbalances. Treatment options may include surveillance with imaging studies, medication to manage hormonal issues, or surgical removal of the tumor in certain cases.

The colon, also known as the large intestine, is a part of the digestive system in humans and other vertebrates. It is an organ that eliminates waste from the body and is located between the small intestine and the rectum. The main function of the colon is to absorb water and electrolytes from digested food, forming and storing feces until they are eliminated through the anus.

The colon is divided into several regions, including the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum, and anus. The walls of the colon contain a layer of muscle that helps to move waste material through the organ by a process called peristalsis.

The inner surface of the colon is lined with mucous membrane, which secretes mucus to lubricate the passage of feces. The colon also contains a large population of bacteria, known as the gut microbiota, which play an important role in digestion and immunity.

Colonic diseases refer to a group of medical conditions that affect the colon, also known as the large intestine or large bowel. The colon is the final segment of the digestive system, responsible for absorbing water and electrolytes, and storing and eliminating waste products.

Some common colonic diseases include:

1. Inflammatory bowel disease (IBD): This includes conditions such as Crohn's disease and ulcerative colitis, which cause inflammation and irritation in the lining of the digestive tract.
2. Diverticular disease: This occurs when small pouches called diverticula form in the walls of the colon, leading to symptoms such as abdominal pain, bloating, and changes in bowel movements.
3. Colorectal cancer: This is a type of cancer that develops in the colon or rectum, often starting as benign polyps that grow and become malignant over time.
4. Irritable bowel syndrome (IBS): This is a functional gastrointestinal disorder characterized by abdominal pain, bloating, and changes in bowel movements, but without any underlying structural or inflammatory causes.
5. Constipation: This is a common condition characterized by infrequent bowel movements, difficulty passing stools, or both.
6. Infectious colitis: This occurs when the colon becomes infected with bacteria, viruses, or parasites, leading to symptoms such as diarrhea, abdominal cramps, and fever.

Treatment for colonic diseases varies depending on the specific condition and its severity. Treatment options may include medications, lifestyle changes, surgery, or a combination of these approaches.

The intestinal mucosa is the innermost layer of the intestines, which comes into direct contact with digested food and microbes. It is a specialized epithelial tissue that plays crucial roles in nutrient absorption, barrier function, and immune defense. The intestinal mucosa is composed of several cell types, including absorptive enterocytes, mucus-secreting goblet cells, hormone-producing enteroendocrine cells, and immune cells such as lymphocytes and macrophages.

The surface of the intestinal mucosa is covered by a single layer of epithelial cells, which are joined together by tight junctions to form a protective barrier against harmful substances and microorganisms. This barrier also allows for the selective absorption of nutrients into the bloodstream. The intestinal mucosa also contains numerous lymphoid follicles, known as Peyer's patches, which are involved in immune surveillance and defense against pathogens.

In addition to its role in absorption and immunity, the intestinal mucosa is also capable of producing hormones that regulate digestion and metabolism. Dysfunction of the intestinal mucosa can lead to various gastrointestinal disorders, such as inflammatory bowel disease, celiac disease, and food allergies.

Pancreatic neoplasms refer to abnormal growths in the pancreas that can be benign or malignant. The pancreas is a gland located behind the stomach that produces hormones and digestive enzymes. Pancreatic neoplasms can interfere with the normal functioning of the pancreas, leading to various health complications.

Benign pancreatic neoplasms are non-cancerous growths that do not spread to other parts of the body. They are usually removed through surgery to prevent any potential complications, such as blocking the bile duct or causing pain.

Malignant pancreatic neoplasms, also known as pancreatic cancer, are cancerous growths that can invade and destroy surrounding tissues and organs. They can also spread (metastasize) to other parts of the body, such as the liver, lungs, or bones. Pancreatic cancer is often aggressive and difficult to treat, with a poor prognosis.

There are several types of pancreatic neoplasms, including adenocarcinomas, neuroendocrine tumors, solid pseudopapillary neoplasms, and cystic neoplasms. The specific type of neoplasm is determined through various diagnostic tests, such as imaging studies, biopsies, and blood tests. Treatment options depend on the type, stage, and location of the neoplasm, as well as the patient's overall health and preferences.

Colonic polyps are abnormal growths that protrude from the inner wall of the colon (large intestine). They can vary in size, shape, and number. Most colonic polyps are benign, meaning they are not cancerous. However, some types of polyps, such as adenomas, have a higher risk of becoming cancerous over time if left untreated.

Colonic polyps often do not cause any symptoms, especially if they are small. Larger polyps may lead to symptoms like rectal bleeding, changes in bowel habits, abdominal pain, or iron deficiency anemia. The exact cause of colonic polyps is not known, but factors such as age, family history, and certain medical conditions (like inflammatory bowel disease) can increase the risk of developing them.

Regular screening exams, such as colonoscopies, are recommended for individuals over the age of 50 to detect and remove polyps before they become cancerous. If you have a family history of colonic polyps or colorectal cancer, your doctor may recommend earlier or more frequent screenings.

Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.

Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.

Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.

Neoplasms: Neoplasms refer to abnormal growths of tissue that can be benign (non-cancerous) or malignant (cancerous). They occur when the normal control mechanisms that regulate cell growth and division are disrupted, leading to uncontrolled cell proliferation.

Cystic Neoplasms: Cystic neoplasms are tumors that contain fluid-filled sacs or cysts. These tumors can be benign or malignant and can occur in various organs of the body, including the pancreas, ovary, and liver.

Mucinous Neoplasms: Mucinous neoplasms are a type of cystic neoplasm that is characterized by the production of mucin, a gel-like substance produced by certain types of cells. These tumors can occur in various organs, including the ovary, pancreas, and colon. Mucinous neoplasms can be benign or malignant, and malignant forms are often aggressive and have a poor prognosis.

Serous Neoplasms: Serous neoplasms are another type of cystic neoplasm that is characterized by the production of serous fluid, which is a thin, watery fluid. These tumors commonly occur in the ovary and can be benign or malignant. Malignant serous neoplasms are often aggressive and have a poor prognosis.

In summary, neoplasms refer to abnormal tissue growths that can be benign or malignant. Cystic neoplasms contain fluid-filled sacs and can occur in various organs of the body. Mucinous neoplasms produce a gel-like substance called mucin and can also occur in various organs, while serous neoplasms produce thin, watery fluid and commonly occur in the ovary. Both mucinous and serous neoplasms can be benign or malignant, with malignant forms often being aggressive and having a poor prognosis.

Colitis is a medical term that refers to inflammation of the inner lining of the colon or large intestine. The condition can cause symptoms such as diarrhea, abdominal cramps, and urgency to have a bowel movement. Colitis can be caused by a variety of factors, including infections, inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), microscopic colitis, ischemic colitis, and radiation therapy. The specific symptoms and treatment options for colitis may vary depending on the underlying cause.

Multiple primary neoplasms refer to the occurrence of more than one primary malignant tumor in an individual, where each tumor is unrelated to the other and originates from separate cells or organs. This differs from metastatic cancer, where a single malignancy spreads to multiple sites in the body. Multiple primary neoplasms can be synchronous (occurring at the same time) or metachronous (occurring at different times). The risk of developing multiple primary neoplasms increases with age and is associated with certain genetic predispositions, environmental factors, and lifestyle choices such as smoking and alcohol consumption.

Skin neoplasms refer to abnormal growths or tumors in the skin that can be benign (non-cancerous) or malignant (cancerous). They result from uncontrolled multiplication of skin cells, which can form various types of lesions. These growths may appear as lumps, bumps, sores, patches, or discolored areas on the skin.

Benign skin neoplasms include conditions such as moles, warts, and seborrheic keratoses, while malignant skin neoplasms are primarily classified into melanoma, squamous cell carcinoma, and basal cell carcinoma. These three types of cancerous skin growths are collectively known as non-melanoma skin cancers (NMSCs). Melanoma is the most aggressive and dangerous form of skin cancer, while NMSCs tend to be less invasive but more common.

It's essential to monitor any changes in existing skin lesions or the appearance of new growths and consult a healthcare professional for proper evaluation and treatment if needed.

Gastrointestinal transit refers to the movement of food, digestive secretions, and waste products through the gastrointestinal tract, from the mouth to the anus. This process involves several muscles and nerves that work together to propel the contents through the stomach, small intestine, large intestine, and rectum.

The transit time can vary depending on factors such as the type and amount of food consumed, hydration levels, and overall health. Abnormalities in gastrointestinal transit can lead to various conditions, including constipation, diarrhea, and malabsorption. Therefore, maintaining normal gastrointestinal transit is essential for proper digestion, nutrient absorption, and overall health.

Colonic pseudo-obstruction, also known as Ogilvie's syndrome, is a medical condition characterized by the absence of an actual physical obstruction in the colon, but with symptoms and radiologic findings that mimic a mechanical intestinal obstruction. It is caused by a dysfunction of the nervous system or muscles in the colon, leading to severe dilation and potential perforation if not treated promptly.

The condition is often associated with underlying medical conditions such as surgery, trauma, infection, electrolyte imbalances, neurologic disorders, and certain medications. The symptoms may include abdominal pain, distention, nausea, vomiting, constipation, and in severe cases, fever and sepsis.

Treatment typically involves decompression of the colon using a nasogastric tube or colonoscopy, as well as addressing any underlying causes. In some cases, surgery may be necessary to remove the excess gas and stool from the colon or to repair a perforation.

Diverticulosis, colonic is a medical condition characterized by the presence of small sacs or pouches (diverticula) that form on the outer wall of the large intestine (colon). These sacs are usually found in the sigmoid colon, which is the part of the colon that is closest to the rectum.

Diverticulosis occurs when the inner layer of the colon's muscle pushes through weak spots in the outer layer of the colon wall, creating small pockets or sacs. The exact cause of diverticulosis is not known, but it may be associated with a low-fiber diet, aging, and increased pressure in the colon.

Most people with diverticulosis do not experience any symptoms, and the condition is often discovered during routine screening exams or when complications arise. However, some people may experience cramping, bloating, and changes in bowel habits.

Diverticulosis can lead to complications such as inflammation (diverticulitis), bleeding, and infection. It is important to seek medical attention if you experience symptoms such as severe abdominal pain, fever, or rectal bleeding, as these may be signs of a more serious condition.

Treatment for diverticulosis typically involves making dietary changes, increasing fiber intake, and taking medications to manage symptoms. In some cases, surgery may be necessary to remove affected portions of the colon.

Kidney neoplasms refer to abnormal growths or tumors in the kidney tissues that can be benign (non-cancerous) or malignant (cancerous). These growths can originate from various types of kidney cells, including the renal tubules, glomeruli, and the renal pelvis.

Malignant kidney neoplasms are also known as kidney cancers, with renal cell carcinoma being the most common type. Benign kidney neoplasms include renal adenomas, oncocytomas, and angiomyolipomas. While benign neoplasms are generally not life-threatening, they can still cause problems if they grow large enough to compromise kidney function or if they undergo malignant transformation.

Early detection and appropriate management of kidney neoplasms are crucial for improving patient outcomes and overall prognosis. Regular medical check-ups, imaging studies, and urinalysis can help in the early identification of these growths, allowing for timely intervention and treatment.

Gastrointestinal motility refers to the coordinated muscular contractions and relaxations that propel food, digestive enzymes, and waste products through the gastrointestinal tract. This process involves the movement of food from the mouth through the esophagus into the stomach, where it is mixed with digestive enzymes and acids to break down food particles.

The contents are then emptied into the small intestine, where nutrients are absorbed, and the remaining waste products are moved into the large intestine for further absorption of water and electrolytes and eventual elimination through the rectum and anus.

Gastrointestinal motility is controlled by a complex interplay between the autonomic nervous system, hormones, and local reflexes. Abnormalities in gastrointestinal motility can lead to various symptoms such as bloating, abdominal pain, nausea, vomiting, diarrhea, or constipation.

A "second primary neoplasm" is a distinct, new cancer or malignancy that develops in a person who has already had a previous cancer. It is not a recurrence or metastasis of the original tumor, but rather an independent cancer that arises in a different location or organ system. The development of second primary neoplasms can be influenced by various factors such as genetic predisposition, environmental exposures, and previous treatments like chemotherapy or radiation therapy.

It is important to note that the definition of "second primary neoplasm" may vary slightly depending on the specific source or context. In general medical usage, it refers to a new, separate cancer; however, in some research or clinical settings, there might be more precise criteria for defining and diagnosing second primary neoplasms.

Adenocarcinoma, mucinous is a type of cancer that begins in the glandular cells that line certain organs and produce mucin, a substance that lubricates and protects tissues. This type of cancer is characterized by the presence of abundant pools of mucin within the tumor. It typically develops in organs such as the colon, rectum, lungs, pancreas, and ovaries.

Mucinous adenocarcinomas tend to have a distinct appearance under the microscope, with large pools of mucin pushing aside the cancer cells. They may also have a different clinical behavior compared to other types of adenocarcinomas, such as being more aggressive or having a worse prognosis in some cases.

It is important to note that while a diagnosis of adenocarcinoma, mucinous can be serious, the prognosis and treatment options may vary depending on several factors, including the location of the cancer, the stage at which it was diagnosed, and the individual's overall health.

Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.

Lipkin M, Deschner E, Troncale F (1970). "Cell differentiation and the development of colonic neoplasms". CA: A Cancer Journal ... "Biochemical measure of the volume doubling time of human pulmonary neoplasms". Cancer. 55 (7): 1530-5. doi:10.1002/1097-0142( ...
Bitterness and Colonic Neoplasms". Digestive Diseases and Sciences. 50 (3): 483-9. doi:10.1007/s10620-005-2462-7. PMID 15810630 ...
April 2002). "Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dubé syndrome". Cancer ... cosegregation of kidney neoplasms with BHD cutaneous lesions was observed in 3 families with a family history of kidney tumors ...
... violet is absorbed into intestinal and neoplastic cells and is used to identify Barrett's esophagus and colonic neoplasms.[ ... characterization of colonic polyps and colorectal cancer, and in screening for dysplasia in individuals with ulcerative colitis ...
... colonic neoplasms MeSH C04.588.274.476.411.307.180.089 - adenomatous polyposis coli MeSH C04.588.274.476.411.307.180.089.500 - ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588. - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...
... appendiceal neoplasms MeSH C06.301.371.411.307 - colorectal neoplasms MeSH C06.301.371.411.307.180 - colonic neoplasms MeSH ... appendiceal neoplasms MeSH C06.405.249.411.307 - colorectal neoplasms MeSH C06.405.249.411.307.180 - colonic neoplasms MeSH ... appendiceal neoplasms MeSH C06.405.469.491.307 - colorectal neoplasms MeSH C06.405.469.491.307.180 - colonic neoplasms MeSH ... cecal neoplasms MeSH C06.405.469.110.417.290 - appendiceal neoplasms MeSH C06.405.469.158 - colonic diseases MeSH C06.405. ...
... compared to histologically normal tissue from individuals who never had a colonic neoplasm. This finding suggests that ... MBD4 expression is reduced in almost all colorectal neoplasms due to methylation of the promoter region of MBD4. Also MBD4 is ...
... compared to histologically normal tissue from individuals who never had a colonic neoplasm. This indicates that an epigenetic ... MBD4 mRNA expression is reduced in colorectal neoplasms due to methylation of the promoter region of MBD4. A majority of ...
... compared to histologically normal tissue from individuals who never had a colonic neoplasm. This finding suggests that ... MBD4 expression is reduced in almost all colorectal neoplasms due to methylation of the promoter region of MBD4. Also MBD4 is ...
Colonic adenocarcinoma metastatic to the thyroid gland (e); the thyroid tissue is positive for thyroglobulin while the ... Thyroid neoplasm is a neoplasm or tumor of the thyroid. It can be a benign tumor such as thyroid adenoma, or it can be a ... Thyroid neoplasm might be classified as benign or malignant.[citation needed] Thyroid adenoma is a benign neoplasm of the ... The first step in diagnosing a thyroid neoplasm is a physical exam of the neck area. If any abnormalities exist, a doctor needs ...
indicated that macrophages and neutrophils in an inflamed colonic epithelium are the source of reactive oxygen species causing ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The word neoplasm is from Ancient Greek νέος- neo 'new' and πλάσμα plasma 'formation, creation'. A neoplasm can be benign, ... The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that ...
Neoplasms / cancer Diverticulitis / Diverticulosis Hernias Inflammatory bowel disease Colonic volvulus (sigmoid, caecal, ... sutures Pseudoobstruction Hernias containing bowel Crohn's disease causing adhesions or inflammatory strictures Neoplasms, ...
Large intestine: nonspecific ulcerative colitis, Crohn's disease, chronic colitis, colonic polyps, colorectal cancer, etc. The ... Small intestine: small intestine neoplasms, smooth muscle tumors, sarcomas, polyps, lymphomas, inflammation, etc. ...
The presence of fresh blood in the terminal ileum is presumed to indicate a non colonic source of bleeding. The overall ... H7 Shigella Salmonella Campylobacter jejuni Hemorrhoids Neoplasm - such as colorectal cancer Angiodysplasia Bleeding from a ... use is a risk factor for diverticular bleeding and NSAID-induced colonic ulcer; and recent colonoscopy with polypectomy ... site where a colonic polyp was removed Inflammatory bowel disease such as Crohn's disease or ulcerative colitis Rectal varices ...
"Faecal microRNAs as a non-invasive tool in the diagnosis of colonic adenomas and colorectal cancer: A meta-analysis". ... it has been demonstrated as an independent prognostic factor in patients with pancreatic neuroendocrine neoplasms. miR-21 has ... "Prognostic relevance of proliferation-related miRNAs in pancreatic neuroendocrine neoplasms". European Journal of Endocrinology ...
It is well documented that malignancy may be only focally present in mucinous neoplasms of the ovary, so thorough sampling is ... The appearance can look similar to colonic cancer. Clear stromal invasion is used to differentiate borderline tumors from ... Mucinous tumors are part of the surface epithelial-stromal tumor group of ovarian neoplasms, and account for approximately 36% ...
These neoplasms are relatively uncommon and typically occur on the scalp, face, and upper extremities. Clinically, ... This association has prognostic import, since cutaneous findings in children with Gardner syndrome generally precede colonic ... Malignant pilomatricoma List of cutaneous conditions List of cutaneous neoplasms associated with systemic syndromes Rapini, ...
2009). "Guanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms". ... the colonic cell line". Biochim. Biophys. Acta. 1498 (1): 32-43. doi:10.1016/s0167-4889(00)00075-6. PMID 11042348. Ciocca V, ...
Colonic transit studies may be used to rule out colonic inertia if there is a history of severe constipation. Continent ... Rarely, a neoplasm (tumour) may form on the leading edge of the intussusceptum. In addition, patients are frequently elderly ... Amaechi I, Papagrigoriadis S, Hizbullah S, Ryan SM (November 2010). "Solitary rectal ulcer syndrome mimicking rectal neoplasm ... anismus and colonic dysmotility exacerbate. Some believe that internal rectal intussusception represents the initial form of a ...
A neoplasm is a tissue whose cells have lost normal differentiation. They can be either benign growths or malignant growths. ... Micrograph of a Peutz-Jeghers colonic polyp - a type of hamartomatous polyp. H&E stain. Micrograph of a tubular adenoma - ... Saunders B, Ginsberg GG, Bjorkman DJ (2008). "How I do it: Removing large or sessile colonic polyps" (PDF). Munich: OMED. ... Paris classification of colorectal neoplasms In colonoscopy, colorectal polyps can be classified by NICE (Narrow-band imaging ...
Gastric and colonic pacemakers have been tried. These are strips placed along the colon or stomach which create an electric ... Bowel obstruction: mechanical or functional obstruction of the bowel, most commonly due to adhesions, hernias or neoplasms. ... Briejer MR, Prins NH, Schuurkes JA (October 2001). "Effects of the enterokinetic prucalopride (R093877) on colonic motility in ... Saunders MD (October 2004). "Acute colonic pseudoobstruction". Current Gastroenterology Reports. 6 (5): 410-6. doi:10.1007/ ...
Gardner syndrome is set apart as a subtype because, in addition to colonic polyps, there are also extra-colonic growths (both ... The incidence of mammary desmoid tumors is less than 0.2% of primary breast neoplasms. In Gardner's syndrome, the incidence ... Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... List of cutaneous conditions List of dental abnormalities associated with cutaneous conditions List of cutaneous neoplasms ...
... and colonic adenomas, a premalignant lesion of colon adenocarcinoma. Furthermore epigenetic silencing of MORT is associated ... lymphoid neoplasm diffuse large B-cell lymphoma, pancreatic adenocarcinoma, rectum adenocarcinoma, skin cutaneous melanoma, and ...
... s are a class of ovarian neoplasms that may be benign or malignant. Neoplasms in this group are ... The appearance can look similar to colonic or ovarian cancer, but typically originates from the appendix (see mucinous ... One rare but noteworthy condition associated with mucinous ovarian neoplasms is pseudomyxoma peritonei. As primary ovarian ... of all ovarian neoplasms In some cases mucinous tumors are characterized by more cysts of variable size and a rarity of surface ...
In the colonic tissues of mice fed diet plus DOC similar changes in biomarkers occurred. Thus, 8-OH-dG was increased, DNA ... 1996). "Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice". Cancer Res. 56 (16): 3842-9. PMID 8706033 ... 1998). "Development of colonic adenocarcinomas in a mouse model of ulcerative colitis". Inflamm. Bowel Dis. 4 (3): 196-202. doi ... After 8-10 months, 45% to 56% of the mice developed colonic adenocarcinomas, and no mice had cancers of the small intestine. On ...
Of solid tumor neoplasms, ovarian cancer is most likely to provoke eosinophilia, though any other cancer can cause the ... Beeken WL, Northwood I, Beliveau C, Baigent G, Gump D (1987). "Eosinophils of human colonic mucosa: C3b and Fc gamma receptor ... The World Health Organization classifies these disorders into a) Myeloid and lymphoid neoplasms with eosinophilia and ... Reiter A, Gotlib J (2017). "Myeloid neoplasms with eosinophilia". Blood. 129 (6): 704-714. doi:10.1182/blood-2016-10-695973. ...
Some solid malignant tumors, ( colonic, uterine and bronchogenic, and head and neck necrotic tumors, are more likely to become ... malignant neoplasms intestinal obstruction; decubitus ulcers; dental extraction; sickle cell disease; diabetes mellitus; ... often to yield colonic flora organisms. These are generally B. fragilis group, Clostridium spp., Enterobacteriaceae and ...
Hairy cell leukemia is also a neoplasm of B lymphocytes, but the neoplastic cells have a distinct morphology under the ... Colonic perforation secondary to chronic lymphocytic leukemia infiltration without Richter transformation. Leuk Lymphoma. 2011 ... ISBN 978-0-7817-5007-3. Frequency of lymphoid neoplasms. (Source: Modified from WHO Blue Book on Tumour of Hematopoietic and ... Choi SM, O'Malley DP (December 2018). "Diagnostically relevant updates to the 2017 WHO classification of lymphoid neoplasms". ...
In 1986, a laboratory worker accidentally bruised herself with the needles she was using to inject colonic cancer cells into ... Frierman EM, Andrews JD (February 1976). "Occurrence of hematopoietic neoplasms in Virginia oysters (Crassostrea virginica)". ... Gugel EA, Sanders ME (December 1986). "Needle-stick transmission of human colonic adenocarcinoma". The New England Journal of ... have been found to be vulnerable to a transmissible neoplasm of the hemolymphatic system - effectively, leukemia. The cells ...
"Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use". Archives ... "The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia". Blood. 127 (20): ... Systemic mastocytosis with associated hematological neoplasm (SM-AHN) Aggressive systemic mastocytosis (ASM) Mast cell leukemia ...
ClinicalTrials.gov: Colonic Neoplasms (National Institutes of Health) * ClinicalTrials.gov: Colorectal Neoplasms (National ...
Lipkin M, Deschner E, Troncale F (1970). "Cell differentiation and the development of colonic neoplasms". CA: A Cancer Journal ... "Biochemical measure of the volume doubling time of human pulmonary neoplasms". Cancer. 55 (7): 1530-5. doi:10.1002/1097-0142( ...
Categories: Colonic Neoplasms Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 4 ...
Humans, Retrospective Studies, Colectomy/methods, Treatment Outcome, Laparoscopy/methods, Colonic Neoplasms/surgery, ... Colonic Neoplasms/surgery; Anastomosis, Surgical/methods}}, language = {{eng}}, month = {{05}}, pages = {{1--7}}, publisher ...
Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dubé syndrome. Cancer Epidemiol Biomarkers ... Nagashima Y, Furuya M, Gotohda H, Takagi S, Hes O, Michal M. FLCN gene-mutated renal cell neoplasms: mother and daughter cases ...
Neoplasms, Coronavirus Infections, Coronavirus, Colonic Neoplasms Ágora Abrasco: Painel: Tabagismo e Covid-19. ...
Colonic Neoplasms / enzymology * Colonic Neoplasms / microbiology * Colonic Neoplasms / prevention & control* * Colony Count, ...
Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dubé syndrome. Cancer Epidemiol Biomarkers ... 34, 35, 36, 37, 38, 39, 40, 41] Colonic polyps and colonic adenocarcinoma had previously been described with Birt-Hogg-Dubé ... Evaluate colonic polyps for malignant potential. Birt-Hogg-Dubé syndrome patients with a history of smoking appear to have more ... Nagashima Y, Furuya M, Gotohda H, Takagi S, Hes O, Michal M. FLCN gene-mutated renal cell neoplasms: mother and daughter cases ...
Powered by Pure, Scopus & Elsevier Fingerprint Engine™ All content on this site: Copyright © 2024 Elsevier B.V. or its licensors and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the Creative Commons licensing terms apply We use cookies to help provide and enhance our service and tailor content. By continuing you agree to the use of cookies. ...
... there is a risk of developing other benign and malignant colon neoplasms and careful follow-up is required. ...
Helicobacter pylori Infection with Atrophic Gastritis Is an Independent Risk Factor for Advanced Colonic Neoplasm. https://www. ...
Colonic Neoplasms Neoplasms, Colon Intervention(s) Biological: Dostarlimab Drug: CAPEOX Drug: FOLFOX ...
Colonic Neoplasms 2 0 Azoospermia 2 1 Disease Susceptibility 2 0 Myelodysplastic Syndromes 2 0 ...
Colonic Neoplasms 55% * Germline variants at SOHLH2 influence multiple myeloma risk. Duran-Lozano, L., Thorleifsson, G., Lopez ...
almost always NIM with no subheadings; check HUMAN; do not routinely add COLONIC NEOPLASMS. ...
Colonic Neoplasms. *Color. *Colorectal Neoplasms. *Comorbidity. *Computational Biology. *Computer Simulation. *Confidence ...
Association between 6-n-propylthiouracil (PROP) bitterness and colonic neoplasms. Dig Dis Sci. 2005 Mar. 50(3):483-9. [QxMD ...
Association between 6-n-propylthiouracil (PROP) bitterness and colonic neoplasms. Dig Dis Sci. 2005 Mar. 50(3):483-9. [QxMD ...
None of these patients had a previous or family history of colonic neoplasms. Colonoscopies of patients with acromegaly were ... Predictors of colonic pathologies in active acromegaly: single tertiary center experience. Iliaz, Raim; Dogansen, Sema Ciftci; ... For this reason, the aim of this study was to determine the frequency of possible colonic pathologies, such as diverticula, ... The incidence of all colonic polyps was significantly higher in the acromegaly group (pâ ¯= 0.012). The frequency of ...
Take advantage of our experts and learn about neoplasms of the gastrointestinal system! This course covers all essentials: ... Peutz-Jeghers syndrome is caused by disruptions in the STK11 gene and is associated with colonic (colorectal) and noncolonic ( ... Each part has subsets of benign and malignant neoplasms that can cause various complications. At times, neoplasms of the GI ... Neoplasms of the Gastrointestinal System by Carlo Raj, MD, Kevin Pei, MD. (9) Gastrointestinal cancers are collectively one of ...
Colonic Neoplasms Explore _. Co-Authors (14) People in Profiles who have published with this person. ...
Colonic neoplasms * Ovarian neoplasms * Pregnancy trimester,... * Rectal neoplasms * Sarcoma * Testicular neoplasms * Show more ...
Colonic Neoplasms/prevention & Control Lung Neoplasms/preventin & Control Neoplasms/preventin & Control Rural Health Rural ...
Colonic Neoplasms/diagnosis , Colonic Neoplasms/diagnostic imaging , Colonic Neoplasms/surgery , Colonoscopy/methods ... Anus Diseases/diagnosis , Colitis , Colonic Diseases/diagnosis , Colonoscopy/methods , Colorectal Neoplasms , Tropical Medicine ...
Colonic Diseases. Intestinal Diseases. Rectal Diseases. Kidney Neoplasms. Urologic Neoplasms. Urogenital Neoplasms. Female ... Neoplasms by Histologic Type. Neoplasms. Lung Neoplasms. Respiratory Tract Neoplasms. Thoracic Neoplasms. Neoplasms by Site. ... Bronchial Neoplasms. Intestinal Neoplasms. Gastrointestinal Neoplasms. Digestive System Neoplasms. Digestive System Diseases. ... Colorectal Neoplasms. Adenocarcinoma. Carcinoma, Renal Cell. Ovarian Neoplasms. Carcinoma. Neoplasms, Glandular and Epithelial ...
We conclude that ESD for early esophageal and gastric cancers is feasible and effective, while colonic ESD requires more ... endoscopic gastrointestinal surgery; gastrointestinal neoplasms; endoscopic submucosal dissection Tipologia 01 Pubblicazione su ... We conclude that ESD for early esophageal and gastric cancers is feasible and effective, while colonic ESD requires more ...
Fat in colonic endoscopic polypectomy specimens. Transplant rejection. Malignancy in superior vena cava syndrome. ... Neoplasms causing paralysis. Significant disagreement between frozen section and final diagnoses. Cytology. ...
  • This article describes a case of adenomatous colonic polyps, adenocarcinoma of sigmoid colon and concurrent malignant carcinoid tumour of ileocaecal junction, detected on colonoscopic examination. (le.ac.uk)
  • Rats treated with C. roseus and A. ilicifolius showed significantly decreased total colonic ACF formation by 61 % to 65 % and 53 % to 65 % respectively when compared with AOM control group and they were effectively comparable to that of 5-Fluorouracil, a standard cemoprotective agent. (um.edu.my)
  • In another abstract in the same session, presented by Óscar Nogales, MD, gastroenterologist from the Hospital General Universitario Gregorio Marañón, Spain, the data showed that the recurrence rate of large non-pedunculated colonic lesions was significantly higher after CS-EMR, compared with the standard technique (conventional EMR), although there was also a trend toward fewer adverse effects. (medscape.com)
  • The aim of current research is to assess the chemoprotective outcomes of ethanolic extracts of C. roseus and A. ilicifolius against azoxymethane (AOM) induced colonic aberrant crypt foci (ACF) in rats. (um.edu.my)
  • 1980. Inhibition by bran of the colonic cocarcinogenicity of bile salts in rats given dimethylhydrazine. (cdc.gov)
  • In order to detect CaR gene alterations that may have occurred during the tumorigenic process, we applied Southern blot, DNA sequence, and RT-PCR analysis to DNA from normal human colon mucosa and from cancerous lesions of different grading, as well as from primary cultured and established colonic carcinoma cell lines (e.g. (ox.ac.uk)
  • Other gastric conditions etiologically associated with H. pylori , such as intestinal metaplasia, adenoma, lymphoma, and adenocarcinoma, were also significantly associated with an increased risk of colonic neoplasm. (medscape.com)
  • In contrast, olive oil dose-dependently downregulated the expression of both Bcl-2 and COX-2 in colonic mucosa and also abrogated the upregulation of Bcl-2 by DMH. (huji.ac.il)
  • Olive oil/sulindac combinations were effective in downregulating colonic mucosa Bcl-2 expression (with the 4 % oil diet) and COX-2 expression (with the 15% oil diet). (huji.ac.il)
  • Caspase-3 activity in colonic mucosa was unaffected by soy oil or soy oil/sulindac combinations. (huji.ac.il)
  • Oral exposure of rats to IQ induces neoplasms of the mammary gland, liver, small intestine, clitoral gland, oral cavity and Zymbal gland in females and neoplasms of the liver, skin, colon, small intestine, oral cavity and Zymbal gland in males. (nih.gov)
  • Carcinoid tumors of the colon are rare, comprising less than 11% of all carcinoid tumors and only 1% of colonic neoplasms. (jomi.com)
  • Conclusions Various forms of gastritis related to H. pylori infection confer an increased risk for colonic neoplasm. (medscape.com)
  • The Birt-Hogg-Dubé syndrome, a genodermatosis characterized by benign tumors of the hair follicle, has been associated with renal and colonic neoplasms and spontaneous pneumothorax, but the risk of developing these disorders is unknown. (nih.gov)
  • The addition of olive oil, on the other hand, significantly enhanced colonic caspase-3 activity. (huji.ac.il)
  • Oral exposure of mice to IQ induces increased incidences of neoplasms of the lung, liver, and forestomach in males and females. (nih.gov)
  • The hypothesis of the present study was that H. pylori gastritis would be a risk factor for all types of colonic neoplasms, and that such risk would also concern the characteristics of the neoplasms with respect to histology, number, size, and location. (medscape.com)
  • In the past, when H. pylori infection was more prevalent, its attributable risk to the occurrence of colorectal neoplasm may have been quite substantial. (medscape.com)
  • [ 1 , 2 ] These previous studies relied on different variables to assess risk factors and the occurrence of colonic neoplasm. (medscape.com)
  • Our aim was to study the association between H. pylori -positive gastritis and the occurrence of any colonic neoplasm. (medscape.com)
  • Similarly, the strength of the association between H. pylori- positive gastritis and colonic neoplasm increased with size and number of the adenomas. (medscape.com)
  • The association between H. pylori gastritis and the occurrence of colonic neoplasm was similar for different locations of the large bowel. (medscape.com)