Colonic Diseases

Crohn Disease

Colon

Enema

Colitis, Ulcerative

Rectum

Colonoscopy

Intestinal Mucosa

Colonic Diseases, Functional

Colonic Neoplasms

Colonic Polyps

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Gastrointestinal disease

Sir William Arbuthnot Lane, 1st Baronet

Functional gastrointestinal disorder

Félicien M. Steichen

List of MeSH codes (C06)

Phenotypic heterogeneity

Gastrointestinal wall

Bowel obstruction

Large intestine

ADAM17

Endoscope

P-Cresol

Hirschsprung's disease

Jejunoileal bypass

Constipation

Type 3 innate lymphoid cells

LCTL

Malabsorption

Butyric acid

Polycarbophil calcium

Cholecystokinin A receptor

Megacolon

Alosetron

Polystyrene sulfonate

Interleukin 26

Gene desert

ROR2

Endoclip

Janus kinase 3

Bile acid

Intestinal epithelium

Alkaline phosphatase

Per- and polyfluoroalkyl substances

Eicosanoid receptor

Estrogen receptor beta

List of Ig Nobel Prize winners

NEDD9

CCL7

MicroRNA

Laxative

ALOX15

Polystyrene (drug delivery)

Clostridium septicum

Corticotropin-releasing hormone

Stem cell marker

T-type calcium channel

CYP26C1

Prostaglandin DP1 receptor

Hydrogen breath test

Folliculin

Clostridial Cytotoxin family

Lck

Food intolerance

Adenocarcinoma

Inflammatory Bowel Di3

• In the final part, we discuss selected diseases associated with increased intestinal permeability such as critically illness, inflammatory bowel diseases, celiac disease, food allergy, irritable bowel syndrome, and - more recently recognized - obesity and metabolic diseases. (typeset.io)
• Quantitative assessment of mucosal architecture using computer-based analysis of confocal laser endomicroscopy in inflammatory bowel diseases. (maunakeatech.com)
• malignancies, benign lesions and inflammatory bowel diseases (IBD). (e-emj.org)

Fermentation8

• The topic of this review is the key end products of colonic fermentation, the SCFA butyric, acetic, and propionic acids. (researchgate.net)
• of colonic fermentation, the SCF A butyric, acetic, and propionic acids. (researchgate.net)
• Psyllium is a dietary fibre which forms a gel when added to water but exactly how psyllium alters colonic fermentation is unknown. (ukri.org)
• We believe that psyllium acts by forming a gel, trapping inulin thereby excluding colonic bacteria and hence slowing and redirecting colonic fermentation to produce less gas but more short chain fatty acids (SCFAs). (ukri.org)
• STUDY 2: This will use our colonic model to assess the effect of the different cellulose preparations on fermentation pathways in the laboratory. (ukri.org)
• STUDY 6: We will give the cellulose with inulin daily for 3 weeks to IBS patients before assessing gas and colonic volumes using MRI, relevant bowel symptoms (gas, pain, bloating) and stool fermentation pathways using our model colon. (ukri.org)
• FODMAPs cause abdominal discomfort, bloating and flatulence by their rapid colonic fermentation which produces gas and distends the colon. (ukri.org)
• 10) Mortensen PB et al.Colonic fermentation of ispaghula, wheat bran, glucose, and albumin to short-chain fatty acidsand ammonia evaluated in 50 subjects. (psyllium.fr)

COLITIS10

• Advances in our understanding of IBD pathogenesis and in diagnostic modalities, therapeutic options and surgical techniques for Crohn's disease and ulcerative colitis have fundamentally altered the landscape of IBD management in the past two decades. (ueg.eu)
• Longitudinal data may indicate that surgical rates for both Crohn's disease and ulcerative colitis are declining, but surgery remains a very real possibility for all IBD patients. (ueg.eu)
• 52% of Ulcerative Colitis (UC) patients who have an active disease are included in this statistic. (maunakeatech.com)
• Confocal laser endomicroscopy in ulcerative colitis: beyond endoscopic assessment of disease activity. (maunakeatech.com)
• We describe a series of four patients with Crohn's disease and one with indeterminate colitis who presented with severe symptoms and signs of gastroparesis. (biomedcentral.com)
• The aim of this case series is to describe clinical characteristics of five patients (four patients with inactive Crohn's disease and a single patient with indeterminate colitis) who had severe symptoms of gastroparesis which could not be attributed to mechanical obstruction or active inflammation, but who all had impaired gastric emptying of solid food. (biomedcentral.com)
• We identified patients by a search of the morbidity database of the department of Gastroenterology and Hepatology which includes the ICD-9 diagnoses of975 patients with Crohn's disease and 821 patients with colitis ulcerosa referred between 1973 and 2004 and by a search of the gastric emptying database which includes 239 patients who underwent a scintigraphic gastric emptying study in our hospital between 1999 and 2004. (biomedcentral.com)
• We selected cases with a diagnosis of IBD including Crohn's disease and ulcerative colitis who also had an impaired gastric emptying by matching the two data bases. (biomedcentral.com)
• We identified four patients with Crohn's disease and one with indeterminate colitis who were diagnosed based upon accepted radiological, endoscopic and histological criteria [ 4 ]. (biomedcentral.com)
• S1P₁ localizes to the colonic vasculature in ulcerative colitis and maintains blood vessel integrity. (weillcornell.org)

Bacteria4

• [ 1 ] VK is also synthesized by colonic bacteria. (medscape.com)
• The amount of gas that is normally present is dependent on the effects of colonic bacteria on the undigested food that reaches the colon and the speed with which the gas passes through the intestines and is passed. (k7herbocare.com)
• These are 'friendly' bacteria that normally live in our digestive, urinary, and genital systems without causing disease. (emedicinehealth.com)
• Friendly' bacteria such as Lactobacillus can help us break down food, absorb nutrients, and fight off 'unfriendly' organisms that might cause diseases such as diarrhea. (emedicinehealth.com)

Microbiota5

• Objective To characterise the influence of diet on abdominal symptoms, anal gas evacuation, intestinal gas distribution and colonic microbiota in patients complaining of flatulence. (bmj.com)
• Prebiotics are substances that can promote the growth of beneficial microorganisms, mainly in the intestinal tract, and will modify the colonic microbiota. (scirp.org)
• G. R. Gibson and M. B. Roberfroid, "Dietary Modulation of the Human Colonic Microbiota-introducing the Concept of Prebiotics," The Journal of Nutrition, Vol. 125, No. 6, 1995, pp. 1401-1412. (scirp.org)
• In a healthy symbi- posed of about as many microorgan- after the pioneering work of Gordon otic state, the colonic microbiota isms as there are cel s in the human and collaborators [1]. (who.int)
• The colonic microbiome view is controversial, some people Metagenomics of the Human Intes- is the most diverse and also the best consider the gut microbiota to be tinal Tract (MetaHIT) consortium re- characterized microbial community. (who.int)

Diverticular15

• In this protocol you will learn about how diverticulosis and diverticular disease develop, and what factors are thought to increase risk of these conditions. (lifeextension.com)
• Targeted natural interventions including probiotics butyrate and fiber may help decrease symptoms and improve diverticular disease. (lifeextension.com)
• When these pouches become inflamed, this characterizes diverticular disease. (lifeextension.com)
• Computed tomography (CT) scan or abdominal ultrasound are the preferred diagnostic imaging modalities to establish a diagnosis of diverticular disease. (lifeextension.com)
• Mild cases of uncomplicated diverticular disease may be confused with irritable bowel syndrome. (lifeextension.com)
• Fecal calprotectin, a non-invasive stool test, is under investigation as a biomarker that may help identify diverticular disease. (lifeextension.com)
• Plant-based diets that are high in fiber may protect against diverticular disease. (lifeextension.com)
• Physical activity and maintaining a healthy weight may reduce the incidence of diverticular disease. (lifeextension.com)
• In a randomized clinical trial of sodium butyrate in 52 people with diverticular disease, less than 7% of those in the butyrate group experienced diverticulitis symptoms compared with slightly more than 31% in the placebo group. (lifeextension.com)
• Gradually increasing fiber until consumption reaches 20-30 g of fiber daily has been recommended by some diverticular disease researchers. (lifeextension.com)
• Several university-associated medical centers recommend supplementing omega-3 fatty acids, including from fish oil, in diverticular disease, as these have anti-inflammatory activity. (lifeextension.com)
• Studies in animal models have shown curcumin can inhibit tumor necrosis factor-alpha, one of the inflammatory chemical messengers associated with diverticular disease and acute diverticulitis. (lifeextension.com)
• Among organic conditions associated with NLH, the most frequent was IBD, followed by infections and diverticular disease. (unicatt.it)
• Through close cooperation with German and international hospitals and research centers we have actively recruited large cohorts with complex disorders and use these for the identification of novel susceptibility genes for gallstone disease, alcoholic liver cirrhosis, colonic diverticular disease (diverticulosis, diverticulitis), colorectal cancer, hemochromatosis, inflammatory bowel disease and sarcoidosis. (uniklinikum-dresden.de)
• Diverticular disease is diverticulosis with associated symptoms. (lecturio.com)

Mucosa Tissues2

• We found correlations between the change in abundance of microbial taxa, butyrate-related colonic metabolites, and methylation-associated host gene expression in colonic tumour mucosa tissues compared with the adjacent normal mucosa tissues. (biomedcentral.com)
• Our study identified associations between previously reported CRC-related microbial taxa, butyrate-related metabolites and DNA methylation-associated gene expression in tumour and normal colonic mucosa tissues from CRC patients, which uncovered a possible mechanism of the role of microbiome in the carcinogenesis of CRC. (biomedcentral.com)

Diagnosis4

• Scott B. Snapper, MD, PhD, chief of the division of gastroenterology, hepatology, and nutrition and the director of the Inflammatory Bowel Disease Center at Boston Children's Hospital, and colleagues, published an overview of the approach to diagnosis and management of patients with very early onset IBD. (gastroenterologyadvisor.com)
• The current clinical approach to very early onset IBD diagnosis and management is stymied by challenge, particularly when the disease manifests in patients with concurrent underlying primary immune deficiencies (PID) - although, noted Dr Snapper and colleagues, most children with very early onset IBD do not present with an underlying PID. (gastroenterologyadvisor.com)
• More recently, earlier diagnosis and advances in surgical techniques have resulted in decreased morbidity and mortality in patients with Hirschsprung disease. (medscape.com)
• OBJECTIVE: The aim of this guideline was to formulate practice guidelines for the diagnosis and treatment of Paget's disease of the bone. (bvsalud.org)

Obstruction11

• Gastrografin study in a patient with obstipation reveals colonic obstruction at the rectosigmoid level. (medscape.com)
• Contrast study demonstrates colonic obstruction at the level of the splenic flexure, in this case due to carcinoma. (medscape.com)
• Care must be taken to exclude urgent causes such as Hirschsprung's disease , cystic fibrosis , lead poisoning , infantile botulism , obstruction, and malformations of the spine. (wikidoc.org)
• Prenatal ultrasonography demonstrating bowel obstruction is rare, except in cases of total colonic involvement. (medscape.com)
• Intermittent distention of the abdomen may be caused by excessive formation of intestinal gas, but also physical or functional obstruction of the intestines. (k7herbocare.com)
• Small bowel enteroclysis, gastroduodenoscopy and colonoscopy with biopsies were performed to estimate the activity of the disease and to exclude organic obstruction. (biomedcentral.com)
• Clinicians should consider impaired gastric emptying when evaluating patients with Crohn's disease and severe symptoms of upper gut dysmotility, which cannot be attributed to active inflammation or organic obstruction of the digestive tract. (biomedcentral.com)
• Symptoms indicative of gastroparesis, such as vomiting and bloating do occur in patients with Crohn's disease, but recurrent and/or persistent symptoms are rare and most clinicians attribute them to active inflammation or mechanical obstruction of the small or large bowel. (biomedcentral.com)
• We found no mechanical obstruction in any of the patients and there were no endoscopical or histological signs of active Crohn's disease. (biomedcentral.com)
• Hirschsprung disease is a developmental disorder characterized by the absence of ganglia in the distal colon, resulting in a functional obstruction. (medscape.com)
• This phenomenon leads to an imbalance of smooth muscle contractility, uncoordinated peristalsis, and a functional obstruction. (medscape.com)

Celiac disease4

• Organic - the most common causes being celiac disease , hypothyroidism , and cow's milk protein allergy. (wikidoc.org)
• Other causes such as cow's milk allergy or celiac disease . (wikidoc.org)
• Celiac disease should also be considered before diagnosing very early onset IBD, particularly in patients presenting with nonbloody diarrhea, malabsorption, anemia, weight loss, and failure to thrive. (gastroenterologyadvisor.com)
• 2012. Peripheral neuropathic symptoms in celiac disease and inflammatory bowel disease. . (weillcornell.org)

Inflammation7

• All these diseases are characterized by inflammation that might be triggered by the translocation of luminal components into the host. (typeset.io)
• It also allows identification of residual colonic inflammation not detectable macroscopically in patients with IBD which in turn can help in determining the need for additional anti-inflammatory therapy and allows prediction of clinical outcomes. (maunakeatech.com)
• CONCLUSION About 1/3 of patients with IBS-type symptoms or suspected IBD presented diffuse colonic NLH, which could be a marker of low-grade inflammation in a conspicuous subset of IBS patients. (unicatt.it)
• Some people take lactobacillus by mouth for general digestion problems, irritable bowel syndrome ( IBS ), colic in babies , inflammatory bowel disease ( IBD ), inflammation of the colon , too much bacterial growth in the intestines , constipation , to improve outcomes after bowel surgery, and to prevent a serious gut problem called necrotizing enterocolitis (NEC) in babies born prematurely. (emedicinehealth.com)
• This review discusses the recent advances in molecular interactions of immune cells, controlled shift of pro- to anti-inflammation, reparative inflammatory metabolisms in tissue regeneration, controlling of an unfavorable microenvironment, dysregulated inflammatory diseases, and emerging therapeutic strategies including the use of biomaterials, which expand therapeutic views and briefly denote important gaps that are still prevailing. (sciencemag.org)
• Functional studies revealed that chronic inflammation leads to an up-regulation of VEGFR2 on IECs. (perkinelmer.com)
• According to a hypothesis, polyphenol (PP) activity against several forms of cancer, proliferative diseases, inflammation and neurodegeneration is mainly exerted through the inhibiting and modulating activities against a wide range of receptors, enzymes and transcription molecules 88 . (bvsalud.org)

Etiology1

• [ 3 ] One possible etiology of Hirschsprung disease is the arrest of aboral neuroblast migration. (medscape.com)

Symptoms12

• Whilst the disease may run a relatively quiescent course, some patients face years of severe, disabling symptoms. (ueg.eu)
• METHODS We selected all cases showing NLH at colonoscopy in a three-year timeframe, and stratified them into symptomatic patients with irritable bowel syndrome (IBS)-type symptoms or suspected inflammatory bowel disease (IBD), and asymptomatic individuals undergoing endoscopy for colorectal cancer screening. (unicatt.it)
• The aim of this case series was to evaluate clinical characteristics of 5 patients with inflammatory bowel disease and symptoms and signs of upper gut dysmotility. (biomedcentral.com)
• All patients underwent an upper gastrointestinal endoscopy to rule out active Crohn's disease in the upper digestive tract and intestinal stenosis as cause of the symptoms. (biomedcentral.com)
• It is also a teaching tool to update physicians and other health care professionals about foodborne illness and remind them of their important role in recognizing suspicious symptoms, disease clusters, and etiologic agents, and reporting cases of foodborne illness to public health authorities. (cdc.gov)
• 2018. Testing and Treating Small Intestinal Bacterial Overgrowth Reduces Symptoms in Patients with Inflammatory Bowel Disease. . (weillcornell.org)
• 2015. The Effect of Breathing, Movement, and Meditation on Psychological and Physical Symptoms and Inflammatory Biomarkers in Inflammatory Bowel Disease: A Randomized Controlled Trial. . (weillcornell.org)
• What's more astounding is that 50 percent of men and 64 percent of women who die from heart disease experience no previous symptoms of it, according to the American Heart Association. (lifeworkswellnesscenter.com)
• Psyllium, a commonly prescribed fibre improves IBS patients' symptoms and reduces the rise in colonic gas volumes after consuming a commonly dietary FODMAP called inulin. (ukri.org)
• In addition to its high fibre and antioxidant levels and low saturated fatty acids and oligosaccharides, the Mediterranean diet may also be useful in improving functional gastrointestinal symptoms. (who.int)
• Symptoms of Hirschsprung disease include intractable constipation, abnormal distention and bilious vomiting, among others. (choc.org)
• I have outlined below the recommended vaccines that cannot prevent transmission of disease either because they are not designed to prevent the transmission of infection (rather, they are intended to prevent disease symptoms), or because they are for non-communicable diseases. (wordpress.com)

Complications6

• Colonic distention from the hard stool can also lead to complications in itself. (pedemmorsels.com)
• DQA1*0102 DQB1*0602 haplotype distinguishes coeliac disease and its complications from gluten unrelated enteropathies. (medline.ch)
• The concept of robotic surgery is not different from laparoscopic surgery in that it is a minimally invasive surgery, and abundant research demonstrates comparable results from both modalities for postoperative complications, oncological outcomes, and functional outcomes. (e-emj.org)
• Surgery is required for complications, failure of medical management, and recurrent disease. (lecturio.com)
• Review post-surgical and functional complications in children with anorectal malformations and Hirschsprung disease. (choc.org)
• Know the workup in children with anorectal malformations and Hirschsprung disease who have complications after their initial surgeries. (choc.org)

Disorders10

• Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. (bvsalud.org)
• Their production and content seem to be altered in a number of disease states, including neoplastic, cardiovascular, immunological and neurological disorders. (nature.com)
• The American Society of Colon and Rectal Surgeons ensures high-quality patient care by advancing the science, prevention, and management of disorders and diseases of the colon, rectum, and anus. (lww.com)
• The Mediterranean diet is associated with a lower risk of functional gastrointestinal disorders. (who.int)
• During his portion of the talk, Dr. Chogle discussed the importance of the team of specialists who work with children with colorectal disorders, including Hirschsprung disease and severe constipation. (choc.org)
• Functional GI and motility disorders which affect the upper GI tract from the esophagus to the stomach. (iffgd.org)
• Functional GI and motility disorders which affect the lower GI tract from the small intestine/bowel, to the large intestine/bowel or colon, to the rectum. (iffgd.org)
• Many other disorders can affect the digestive tract, with uniquely identifying features which differentiate them from functional GI or motility disorders. (iffgd.org)
• The term "functional" is generally applied to disorders where the body's normal activities is impaired. (iffgd.org)
• In phase three the researchers performed quantitative psychometric analyses of the resulting symptom scales in a US general population control sample (n=1,177) and 865 patients with irritable bowel syndrome, inflammatory bowel disease, systemic sclerosis and other common GI disorders. (helpforibs.com)

Diverticulosis3

• Diverticulosis, Colonic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
• This graph shows the total number of publications written about "Diverticulosis, Colonic" by people in this website by year, and whether "Diverticulosis, Colonic" was a major or minor topic of these publications. (ouhsc.edu)
• Below are the most recent publications written about "Diverticulosis, Colonic" by people in Profiles. (ouhsc.edu)

Epithelium4

• The affected segment of mucosal epithelium, which contains several amebae (arrows) is jumbled and sloughing from the underlying lamina propria (LP). Relatively normal colonic epithelium is present at right (arrowhead). (cdc.gov)
• They also induce changes in colonic epithelium stimulating proliferation in the crypts, increasing the concentration ofpolyamines, changing the profile of mucins, and modulating endocrine as well as immune functions. (cambridge.org)
• Colorectal cancer is the result of progressive transformation of colonic epithelium into neoplastic tissue. (cas.cz)
• Applications of intestinal organoid cultures include studying the development and function of intestinal epithelium, modeling intestinal diseases, and screening molecules for both efficacy and toxicity in an intestinal model. (stemcell.com)

Abdominal1

• Despite significant constipation and abdominal distention, children with Hirschsprung disease rarely develop encopresis (fecal incontinence secondary to impacted stools). (medscape.com)

Lesions1

• The role of fibroblasts is further described in cutaneous T-cell lymphoma (CTCL) which refer to a group of lymphoproliferative diseases characterized by the accumulation of malignant T cells in chronically inflamed skin lesions. (frontiersin.org)

Patients20

• b) For the cyclic and non-life-threatening nature of the disease, a long-term study of 4-6 months or more of active treatment to establish efficacy is considered to be inappropriate in the large majority of patients. (nih.gov)
• This predisposition is more common in patients with longer-segment disease. (medscape.com)
• RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients. (medscape.com)
• Functional analyses of RET mutations in Chinese Hirschsprung disease patients. (medscape.com)
• Despite the evidence, 5-ASA drugs continue to be widely used for the management of around one third of patients with Crohn's disease, 6 a situation that is scarcely any better in large clinical trial centres. (ueg.eu)
• The LIR!C study recruited patients without a prior history of surgery or biologic therapy and who had limited, nonstricturing, nonpenetrating ileal disease that was refractory to thiopurine or steroids-in other words, a cohort that would, in many centres, be managed by escalation to biologic therapy. (ueg.eu)
• How to predict clinical relapse in inflammatory bowel disease patients. (maunakeatech.com)
• AIM To evaluate the prevalence of nodular lymphoid hyper-plasia (NLH) in adult patients undergoing colonoscopy and its association with known diseases. (unicatt.it)
• Interestingly, 31% of IBS patients presented diffuse colonic NLH. (unicatt.it)
• Background: Functional iron deficiency has been found to be a common cause of poor response to erythropoiesis stimulating agents in anaemic patients with chronic kidney disease (CKD). (bvsalud.org)
• Objectives: Assess the functional iron status of patients with chronic kidney disease. (bvsalud.org)
• The study subjects were chronic kidney disease patients with age and sex matched healthy controls. (bvsalud.org)
• Few studies have described patients with foregut dysmotility in inflammatory bowel disease. (biomedcentral.com)
• The patients were all treated in our institute which is a tertiary referral centre for inflammatory bowel disease (IBD) in the Netherlands. (biomedcentral.com)
• After having ruled out active inflammatory disease gastric emptying was evaluated by a scintigraphy in all patients. (biomedcentral.com)
• Chelation therapy" is a non-surgical infusion therapy that has been used for improving circulation and reducing arteriosclerosis in patients with heart disease. (lifeworkswellnesscenter.com)
• In patients with Hirschsprung disease, both myenteric and submucosal plexuses are absent. (medscape.com)
• Patients with peritoneal metastatic disease may benefit from surgical cytoreduction and hyper-thermic intraperitoneal chemotherapy (HIPEC). (medscape.com)
• Obstructed defecation - 50% of patients have this problem and it is due to mechanical and functional causes. (nutritionvista.com)
• In phase one they developed candidate items by performing a systematic literature review and conducting 12 disease-specific focus groups involving 102 GI patients. (helpforibs.com)

Diverticula2

• A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. (ouhsc.edu)
• These diverticula can become symptomatic, however, when associated with diseases. (lecturio.com)

Tissues1

• Deep infiltrating endometriosis (DIE) is considered the most aggressive presentation of the disease, penetrating more than 5 mm in affected tissues, and it is reported in approximately 20% of all women with endometriosis. (hindawi.com)

Genes4

• The research on screening differentially expressed genes in Hirschsprung's disease by using Microarray. (medscape.com)
• The barrier assessments are further hindered by the natural variability of this functional entity depending on species and genes as well as on diet and other environmental factors. (typeset.io)
• In our group we focus on genes, which have been identified by GWAS to be involved in many liver diseases, such as NAFLD, ALD, cirrhosis and hepatocellular carcinoma. (uniklinikum-dresden.de)
• If you have an autoimmune disease, I want you to understand, you have the genetic propensity for certain genes to be activated or triggered that set autoimmune disease in motion. (drtabatha.com)

Lesion2

• Colonic lesion severity is a conglomerate statistical measure (principal component) of 4 scores of lesion severity. (cdc.gov)
• Colonic lesion characterization in inflammatory bowel disease: A systematic review and metaanalysis. (maunakeatech.com)

Acute2

• follows damage to the intestinal mucosa - eg, acute viral or bacterial gastroenteritis, parasitic infection, uncontrolled coeliac disease, inflammatory bowel disease, chemotherapy, long courses of antibiotics or severe malnutrition. (patient.info)
• Acute kidney injury (AKI) is a life-threatening disease with high mortality characterized by an abrupt decrease of the kidney glomerular filtration rate, extra-kidney consequences (cardiovascular diseases, lung injury, neurological impairment) and high risk of secondary chronic kidney disease (CKD). (hrb.ie)

Colon6

• Objective: The aim isto study clinicai characteristics and the association among colon and esophagus dismotilities in adolescents with functional constipation. (ufrgs.br)
• Thought you might appreciate this item(s) I saw in Diseases of the Colon & Rectum. (lww.com)
• Functional foods, such as 'prebiotics' and 'probiotics', dietary fibers, and other dietary components that target the colon and affect its environment enhancing short fatty acid (SCFA) production have been at the forefront. (researchgate.net)
• Other health benefits of probiotics, which have been documented or indicated, include suppressing colon cancer, preventing vaginitis, reducing serum cholesterol, improving bowel regularity and maintaining remission in inflammatory bowel disease. (caloriecontrol.org)
• Mesenteric fat, vessels and lymph nodes were resected en block with the ascending colon. (medscape.com)
• Low FODMAP diets, although widely adopted, are expensive, inconvenient and may have negative effects on health by excluding high fibre foods (HFF) that protect against obesity-related diseases and colon cancer. (ukri.org)

Recurrent1

• A review of each patient's history of frequent or recurrent fevers, opportunistic or refractory infections, rashes, arthritis, arthralgias, and perianal disease is key. (gastroenterologyadvisor.com)

Colorectal8

• Minimally invasive surgery for colorectal disease has now become the standard treatment in Republic of Korea. (e-emj.org)
• Surgery involving the rectum benefits the most among colorectal diseases owing to technical difficulties in rectum dissection. (e-emj.org)
• Since the introduction of laparoscopic colorectal surgery in the early 1990s, minimally invasive surgery (MIS) for colorectal disease has now become the standard treatment in Republic of Korea (Korea). (e-emj.org)
• The first robot-assisted surgery performed for colorectal disease was in 2001 with the Da Vinci telerobotic surgical system. (e-emj.org)
• This article reviews the clinical impacts of applying robotic surgical systems to treating colorectal diseases. (e-emj.org)
• Also, the diverse spectrum of colorectal diseases (malignant, benign, IBD, etc.) presents dissimilar practices and indications for adapting robotic surgery. (e-emj.org)
• We focus on changes in DNA methylation in combination with single nuclei RNA-Seq, snATAC-Seq, spatially resolved transcriptomics and Methyl-Seq to identify disease driving molecular pathways in liver diseases, such as non-alcoholic fatty liver disease (NAFLD), hepatocellular carcinoma and colorectal liver metastases. (uniklinikum-dresden.de)
• In addition, we have shown that disruption of circadian regulation in colonic neoplastic tissue in murine model of colorectal cancer is associated with inflammatory bowel disease. (cas.cz)

Bowel12

• Langer JC, Betti PA, Blennerhassett MG. Smooth muscle from aganglionic bowel in Hirschsprung's disease impairs neuronal development in vitro. (medscape.com)
• The prevalence of inflammatory bowel disease (IBD) is ~0.5%-1% and rising. (ueg.eu)
• Although there has been some suggestion of benefit for the maintenance of remission of small-bowel Crohn's disease after surgical resection, the effect sizes are extremely small. (ueg.eu)
• Cellvizio® is the real-time in vivo cellular imaging platform that allows you to observe, understand, and predict relapse and remission cycles while managing Inflammatory Bowel Disease. (maunakeatech.com)
• Personalized Inflammatory Bowel Disease Care Reduced Hospitalizations. (maunakeatech.com)
• Very early onset inflammatory bowel disease (IBD) is the fastest-growing incidence of IBD in some patient populations. (gastroenterologyadvisor.com)
• [1] Other causes include diarrhea , sexually transmitted infections , inflammatory bowel disease , childbirth , HIV/AIDS , anal cancer , and anal sex . (mdwiki.org)
• When fissures are found laterally, tuberculosis, occult abscesses, leukemic infiltrates, carcinoma, acquired immunodeficiency syndrome (AIDS) or inflammatory bowel disease should be considered as causes. (mdwiki.org)
• Cerebral venous thrombosis in inflammatory bowel disease. (weillcornell.org)
• Functional constipation is characterized by a slowing of bowel movements with no structural or biochemical disorder, painful defecation and sometimes faecal incontinence (3). (who.int)
• Hirschsprung disease is the absence of intrinsic ganglion cells in the bowel wall (specifically the submucosal and myenteric plexuses). (choc.org)
• Short bowel syndrome (SBS) occurs when the functional mass of the small intestine is insufficient for adequate digestion of food and absorption of nutrients and fluids ( 21 21. (scielo.br)

Crohn's11

• That oral aminosalicylates (active ingredient 5-aminosalicylic acid [5-ASA]) are not an effective treatment option for maintenance therapy in Crohn's disease has been robustly demonstrated. (ueg.eu)
• Some have advocated for the use of 5-ASA to maintain remission in colonic Crohn's disease, but there is no good quality evidence to support this, either from a dedicated colonic Crohn's trial, or from either subgroup analysis or meta-analysis of existing maintenance studies. (ueg.eu)
• 2 Indeed, it is noteworthy that even without such a meta-analysis, no single RCT has ever shown a statistically significant benefit of 5-ASA in maintenance therapy for Crohn's disease. (ueg.eu)
• 3 Expert consensus guidelines do not recommend the use of 5-ASA in Crohn's disease. (ueg.eu)
• 7 This may reflect a lack of cheap, nontoxic treatments for mild Crohn's disease, as well as the legacy of conflicting information around 5-ASA formulations when they were first developed. (ueg.eu)
• 1 As a result, 187,000 hospitalizations per year, take place, specifically for Crohn's disease (CD) in the US. (maunakeatech.com)
• Predicting relapse in Crohn's disease: a biopsychosocial model. (maunakeatech.com)
• Prediction of clinical outcomes in Crohn's disease by using confocal laser endomicroscopy: results from a prospective multicenter study. (maunakeatech.com)
• Crohn's disease is a chronic inflammatory condition of unknown aetiology, which may involve the whole digestive tract from the oral cavity to the anus. (biomedcentral.com)
• Vedolizumab and Infliximab Combination Therapy in the Treatment of Crohn's Disease. (weillcornell.org)
• 2010. Crohn's disease is associated with restless legs syndrome. . (weillcornell.org)

Crypts1

• Neoplastic conditions lead to hyperproliferation of colonic crypts accompanied by delay or inhibition in cellular differentiation and apoptosis and progresses through a series of stages through formation of polyps that can be transformed into malignant cancer. (cas.cz)

Perforation1

• This may progress to colonic perforation, causing life-threatening sepsis. (medscape.com)

Diabetes2

• Systemic diseases such as cystic fibrosis , diabetes mellitus , hyper or hypothyroidism , Down syndrome . (wikidoc.org)
• The following health benefits are attributed to prebiotics: relief from poor digestion of lactose, increased resistance to bacterial infection, better immune response and possible protection against cancer, reduction of the risk of diseases such as intestinal disease, cardiovascular disease, non-insulin dependent diabetes, obesity and osteoporosis. (scirp.org)

Hepatic2

• PRONOSISThe prognosis for dogs and cats with hepatic lobe torsion is good if the underlying disease can be effectively treated. (madoogame.online)
• Also note the thickness of the colonic hepatic flexure. (medscape.com)

Microbial1

• Recent changes in human demographics and food preferences, changes in food production and distribution systems, microbial adaptation, and lack of support for public health resources and infrastructure have led to the emergence of novel as well as traditional foodborne diseases. (cdc.gov)

Inulin1

• D. Bosscher, J. Loo-Van and A. Franck, "Inulin and Oligofructose as Prebiotics in the Prevention of Intestinal Infections and Diseases," Nutrition Research Reviews, Vol. 19, No. 2, 2006, pp. 216-226. (scirp.org)

Hirschsprung's5

• Constipation must be differentiated from infantile dischezia, Hirschsprung's disease , and cystic fibrosis . (wikidoc.org)
• Hirschsprung's disease can present with difficulties in passing stool in the neonatal period because of colonic agangliosis. (wikidoc.org)
• However, Hirschsprung's disease would also present with bilious vomiting , refusal to feed, and a fever caused by severe enterocolitis . (wikidoc.org)
• Heanue TA, Pachnis V. Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies. (medscape.com)
• Okamoto E, Takashi U. Embryogenesis of intramural ganglia of the gut and its relation to Hirschsprung's disease. (medscape.com)

Gastroenterology1

• In this case-control study, 221 children with functional constipation (cases) were selected from a paediatric gastroenterology clinic between May 2018 and September 2019, and 230 children without constipation (controls) were randomly selected from those attending a well-child check-up. (who.int)

Cardiovascular Diseases1

• This diet is very important for healthy life and has been shown to have preventative effects on some diseases such as cardiovascular diseases, metabolic diseases, and various cancers (9,10). (who.int)

Centers3

• Centers for Disease Control and Prevention. (cdc.gov)
• The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
• The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)

Motility1

• Colonic slow transit (or hypo motility). (nutritionvista.com)

Clinical7

• With the restrictions on the use of clinical endpoints, validated biomarkers for gut health and immune health in relation to reduction in disease risk are needed. (typeset.io)
• Animals with hepatobiliary disease can develop clinical signs associated with ammonium biurate urolithiasis such as stranguria, pollakiuria or haematuria. (madoogame.online)
• V. Sousa, E. Santos and V. Sgarbieri, "The Importance of Prebiotics in Functional Foods and Clinical Practice," Food and Nutrition Sciences , Vol. 2 No. 2, 2011, pp. 133-144. (scirp.org)
• She's been a clinical instructor and taught functional Integrative Medicine at Columbia University. (drtabatha.com)
• Today, chelation therapy has become so popular that the National Center for Complementary and Alternative Medicine and the National Heart, Lung, and Blood Institute are conducting the first large-scale, $30 million dollar clinical trial to study chelation's effectiveness against heart disease. (lifeworkswellnesscenter.com)
• Mechanisms of disease : an introduction to clinical science / edited by S. Tomlinson, A. M. Heagerty, A. P. Weetman. (who.int)
• The eight scales can be used together or individually for clinical practice and clinical research in a disease-agnostic manner. (helpforibs.com)

Children with functional constipation1

• In contrast, children with functional constipation or stool-withholding behaviors more commonly develop encopresis. (medscape.com)

Intestinal tract1

• Probiotics may also help keep the intestinal tract more acidic, making it difficult for disease causing organisms or pathogens to persist. (caloriecontrol.org)

Constipation in Children3

• Functional - This is the most common type of constipation in children where there is no anatomic or systemic cause. (wikidoc.org)
• Functional constipation in children is diagnosed clinically and using the Rome criteria (4). (who.int)
• A recent study reported a low prevalence of functional constipation in children with good adherence to the Mediterranean diet (11). (who.int)

Autoimmune Diseases1

• But essentially, autoimmune diseases all have the same disease process. (drtabatha.com)

Adult2

• Introduction: Functional constipation occurs in almost 20% of the adult population and can be associated with dismotilities in other digestive segments. (ufrgs.br)
• Adult Colo-Colonic Intussusception in the Setting of Invasive Mucinous Adenocarcinoma: A Case Report. (medline.ch)

Transit time1

• The colonic transit time permits a four-group classification: slow transit constipation, anorectal dysfunction, slow transit constipation associated with anorectal dysfunction, and normal transit. (ufrgs.br)