Colonic diseases. Medical search

Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).

A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.

A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.

Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.

The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.

Endoscopic examination, therapy or surgery of the luminal surface of the colon.

Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.

Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

Tumors or cancer of the COLON.

Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.

Reconstruction for chronic dysfunction of ileoanal pouches. (1/670)

OBJECTIVE: A retrospective review was performed to determine the results after surgical reconstruction for chronic dysfunction of ileal pouch-anal procedures for ulcerative colitis and familial colonic polyposis at a university medical center. METHODS: During the 20-year period from 1978 to 1998, 601 patients underwent colectomy and ileal pouch-anal anastomosis (IPAA) for ulcerative colitis, familial colonic polyposis, or Hirschsprung's disease. A J pouch was used for 351 patients, a lateral pouch for 221, an S pouch for 6, and a straight pull-through for 23. Acute complications after pouch construction have been detailed in previous publications and are not included in this study. Chronic pouch stasis with diarrhea, frequency, urgency, and soiling gradually became more severe in 164 patients (27.3%), associated with pouch enlargement, an elongated efferent limb, and obstruction to pouch outflow, largely related to the pouch configuration used during the authors' early clinical experience. These patients were sufficiently symptomatic to be considered for reconstruction (mean 68 months after IPAA). Transanal resection of an elongated IPAA spout was performed on 58 patients; abdominoperineal mobilization of the pouch with resection and tapering of the lower end (AP reconstruction) and ileoanal anastomosis on 83; pouch removal and new pouch construction on 7; and conversion of a straight pull-through to a pouch on 16. RESULTS: Good long-term results (mean 7.7 years) with improvement in symptoms occurred in 98% of transanal resections, 91.5% of AP reconstructions, 86% of new pouch constructions, and 100% of conversions of a straight pull-through to a pouch. The average number of bowel movements per 24 hours at 6 months was 4.8. Complications occurred in 11.6% of reconstructed patients. Five of the 164 patients (3.1%) required eventual pouch removal and permanent ileostomy. The high rate of pouch revision in this series of patients undergoing IPAA is due to a policy of aggressive correction when patients do not experience an optimal functional result, or have a progressive worsening of their status. CONCLUSIONS: Although occasionally a major undertaking, reconstruction of ileoanal pouches with progressive dysfunction due to large size or a long efferent limb has resulted in marked improvement in intestinal function in >93% of patients and has reduced the need for late pouch removal. (+info)

The pathophysiology of disseminated Mycobacterium avium complex disease in AIDS. (2/670)

Mycobacterium avium complex (MAC) organisms cause disseminated disease in patients with AIDS. The organisms penetrate the gastrointestinal mucosa by unknown mechanisms and are phagocytosed by macrophages in the lamina propria. These cells cannot kill the organisms, and MAC spreads through the submucosal tissue. Lymphatic drainage transports mycobacteria to abdominal lymph nodes, from which the organisms enter the bloodstream. Hematogenous spread can occur to many sites, but spleen, bone marrow, and liver are the most common. Tissue destruction is rare, and most signs and symptoms of MAC disease are due to elaboration of cytokines. MAC is rarely the direct cause of death but increases the risk for superinfection; death may result from malnutrition or other infections. (+info)

Psoas abscesses complicating colonic disease: imaging and therapy. (3/670)

Most surgeons think of psoas abscesses as a very rare condition related to tuberculosis of the spine, but in contemporary surgical practice they are more usually a complication of gastrointestinal disease. A case note study was undertaken on all patients treated for psoas abscess at two large hospitals in the mid-Trent region over a 2-year period. All seven patients presented with pyrexia, psoas spasm, a tender mass and leucocytosis. The diagnosis was made on abdominal radiographs in one patient, CT scan in three, MRI in two, and ultrasound in one. Aetiological factors included Crohn's disease in three, appendicitis in two, and sigmoid diverticulitis and metastatic colorectal carcinoma in one each. Six patients underwent transabdominal resection of the diseased bowel, retroperitoneal debridement and external drainage of the abscess cavity. Percutaneous drainage was performed in one. Two patients had more than one surgical exploration for complications. There were no deaths and the hospital stay ranged from 8-152 days. Psoas abscess can be a difficult and protracted problem. Bowel resection, thorough debridement, external drainage and concomitant antibiotics are essential for psoas abscesses complicating gastrointestinal disease. Defunctioning stomas may be necessary. However, in some cases a multidisciplinary approach may be required, as psoas abscesses can involve bone and joints. (+info)

The colonic mesenteric margin is most susceptible to injury in an experimental model of colonic ulceration. (4/670)

BACKGROUND: Crohn's disease ileal ulcers and indomethacin-induced jejunal ulceration in the rat tend to occur in the mucosa nearest to the mesentery (mesenteric margin), an area of the bowel wall that has a critical blood supply. Mercuric chloride induces caecal and colonic ulceration in the Brown Norway rat. AIM: To examine whether the mesenteric margin is more sensitive to injury by a substance known to be vasculotoxic in the caecum and colon. METHODS: Brown Norway rats received a single subcutaneous dose of either mercuric chloride 1 mg/kg or saline. The gastrointestinal tract was examined macro- and microscopically for lesions 48 h later. The vascular anatomy of the normal rat colon and caecum was also examined using the carbon ink perfusion technique. RESULTS: Mercuric chloride induced caecal and colonic ulceration preferentially along the mesenteric margin of the bowel wall. Histologically, the lesions showed mucosal necrosis and neutrophil infiltration. There was also extensive vascular degeneration/necrosis with microaneurysm formation and extensive submucosal haemorrhage. Cellular infiltration of the vasculature was not a feature. The caecal and colonic mesenteric margins in control rats were supplied by small end arteries. CONCLUSIONS: The colonic and caecal mesenteric margins are susceptible to injury by mercuric chloride, a chemical known to induce haemorrhagic vasculopathy in the rat gastrointestinal tract. The large bowel mesenteric margin may be susceptible to injury by mercuric chloride because of the critical blood supply to that side of the bowel wall. (+info)

Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor. (5/670)

Inducible nitric oxide synthase (iNOS) is overexpressed in colonic tumors of humans and also in rats treated with a colon carcinogen. iNOS appear to regulate cyclooxygenase-2 (COX-2) expression and production of proinflammatory prostaglandins, which are known to play a key role in colon tumor development. Experiments were designed to study the inhibitory effects of S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea (PBIT) a selective iNOS-specific inhibitor, measured against formation of azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF). Beginning at 5 weeks of age, male F344 rats were fed experimental diets containing 0 or 50 p.p.m. of PBIT, or 2000 p.p.m. of curcumin (non-specific iNOS inhibitor). One week later, rats were injected s.c. with AOM (15 mg/kg body wt, once weekly for 2 weeks). At 17 weeks of age, all rats were killed, colons were evaluated for ACF formation and colonic mucosa was assayed for isoforms of COX and NOS activities. Both COX and iNOS activities in colonic mucosa of the AOM-treated rats were significantly induced. Importantly, 50 p.p.m. PBIT suppressed AOM-induced colonic ACF formation to 58% (P < 0.0001) and crypt multiplicity containing four or more crypts per focus to 78% (P < 0.0001); it also suppressed AOM-induced iNOS activity. Curcumin inhibited colonic ACF formation by 45% (P < 0.001). These observations suggest that iNOS may play a key regulatory role in colon carcinogenesis. Developing iNOS-specific inhibitors may provide a selective and safe chemopreventive strategy for colon cancer treatment. (+info)

Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon. (6/670)

The effect of dietary fish oil on colonic crypt cell apoptosis and proliferation was examined in male Wistar rats, 24 and 48 h after administration of 1,2-dimethylhydrazine (DMH), and its influence on the induction of aberrant crypt foci (ACF) in the distal colon was assessed. Rats (125-150 g) fed a high-fat semi-synthetic diet containing corn oil (CO) were given DMH (30 mg/kg body wt) or a sham injection of EDTA/NaCl. Animals were then fed either the CO diet or a diet in which fish oil (EPA 18.7%; DHA 8%) was substituted for corn oil. Subgroups of rats (n = 5) were killed after 24 and 48 h, and crypt cell apoptosis and proliferation were quantified by morphological criteria in isolated intact crypts from the mid and distal colon. Consumption of the fish oil diet (FO) was associated with increased apoptotic cell death (P < 0.001) and suppression of proliferation (P < 0.05) in colonic crypts both 24 and 48 h after DMH. In a second experiment, animals were given three injections of DMH or sham injections of carrier at weekly intervals. For 48 h after each injection animals were fed either the CO or FO diet, but otherwise maintained on the CO throughout. The number and crypt multiplicity of ACF in the distal colon were determined after 18 weeks, and animals given the FO diet for the 48 h period following carcinogen administration were found to have significantly fewer ACF than rats fed the CO diet (P < 0.05). The data demonstrate that the fatty acid composition of the diet is an important determinant in the induction of carcinogenesis by DMH. The proliferative and apoptotic response of the colonic crypt to carcinogen and fish oil, coupled with the reduced incidence of ACF, suggest n-3 PUFA can protect against the carcinogenic effects of DMH by mediating changes in the balance proliferation and cell death. (+info)

Laparoscopic-assisted colectomy: a comparison of dissection techniques. (7/670)

BACKGROUND AND OBJECTIVES: Mobilization of the colon and dissection of the mesentery are difficult laparoscopic techniques. Traditional methods have been used for this dissection, but often with great difficulty. The ultrasonically activated shears, when introduced in 1993, had the possibility to make this dissection less technically difficult. This is a retrospective review of the use of these shears for these techniques during laparoscopic-assisted colectomy. MATERIALS AND METHODS: Eighty-five patients underwent a laparoscopic-assisted right hemicolectomy or sigmoid resection. Colon mobilization and mesenteric dissection were completed intracorporeally. Complications, operative time, estimated blood loss, and length of stay were compared for resections completed with and without the ultrasonically activated shears. RESULTS: Thirty-six patients had laparoscopic-assisted colectomy without the shears, and 49 patients had the procedure with the shears. There were no complications due to the ultrasonic energy. Use of the shears resulted in shorter operative times (170 min. vs. 187 min., p=0.1989), similar median blood loss (98 mL vs. 95 mL, p=0.7620), and shorter lengths of stay (4.3 days vs. 6.9 days, p=0.0018). CONCLUSIONS: The ultrasonically activated shears are safe and effective for colon mobilization and mesenteric division. The use of the shears may result in shorter operative times and shorter lengths of stay. (+info)

Laparoscopic colon surgery for benign disease: a comparison to open surgery. (8/670)

BACKGROUNDS AND OBJECTIVES: There remains a debate in the literature about the advisability of laparoscopic surgery for malignant disease of the colon. Current prospective studies will hopefully answer this question. However, for benign diseases of the colon, we believe laparoscopic surgery offers many advantages including decreased postoperative pain, early discharge from the hospital, and early return to normal activities. We retrospectively reviewed our experience with laparoscopic colectomies for benign disease to see whether these procedures could be done safely and if the proposed advantages could be realized. METHODS: Thirty-eight laparoscopic colon resections performed for benign disease were compared to 39 open colon resections with respect to operating times, length of hospital stay, estimated blood loss, days until first postoperative bowel movement, and complications. RESULTS: The laparoscopic colon resection group had decreased length of stay, less blood loss, earlier return of bowel function, and an equivalent number of complications. Laparoscopic cases did take an average of 24 minutes longer. CONCLUSION: The use of laparoscopic colon surgery for benign disease not only affords the patient the advantage of the laparoscopic approach, but also allows the surgeon to gain experience while awaiting the results of ongoing trials for laparoscopic colon surgery in malignant disease. (+info)

Timothy R. Koch (2003). Colonic diseases. Humana Press. pp. 387-. ISBN 978-0-89603-961-2. Retrieved 2010-11-12. Malone PS, ... "Hirschsprung's disease". Genetic and Rare Diseases Information Center (GARD) - an NCATS Program. 2017. Archived from the ... The Malone antegrade colonic enema (ACE) is also an option. In a Malone ACE, a tube goes through the abdominal wall to the ... Hirschsprung's disease (HD or HSCR) is a birth defect in which nerves are missing from parts of the intestine. The most ...

https://en.wikipedia.org/wiki/Hirschsprung's_disease

"Clinical manifestations and diagnosis of colonic diverticular disease". Literature review. "Diverticular Disease". www.niddk. ... Colonic perforation due to diverticular disease may be classified using the Hinchey Classification. The signs and symptoms of ... "Diverticular Disease". The Lecturio Medical Concept Library. Retrieved 12 July 2021. "Diverticular disease of the colon". The ... Diverticular disease is when problems occur due to diverticulosis, a condition defined by the presence of pouches in the wall ...

https://en.wikipedia.org/wiki/Diverticular_disease

Anorectal and Colonic Diseases: A Practical Guide to their Management. Springer. ISBN 978-3-54069418-2. (Orphaned articles from ... Ehrenpreis, Eli (2003). Anal and Rectal Diseases Explained. Remedica. ISBN 978-1-901346-67-1. Cohee, Mark W.; Hurff, Ashlee; ...

https://en.wikipedia.org/wiki/Anorectal_disorder

in 1978 classifies a colonic perforation due to diverticular disease. The classification is I-IV: Hinchey I - localised abscess ... Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Colorectal Disease 12(9):862-7, 2010 ... Hinchey, E.J., Schaal, P.G. and Richard, G.K. Treatment of perforated diverticular disease of the colon. Advances in Surgery 12 ... para-colonic) Hinchey II - pelvic abscess Hinchey III - purulent peritonitis (the presence of pus in the abdominal cavity) ...

https://en.wikipedia.org/wiki/Hinchey_Classification

... , specifically colonic diverticulitis, is a gastrointestinal disease characterized by inflammation of abnormal ... Pemberton, John H (16 June 2016). "Colonic diverticulosis and diverticular disease: Epidemiology, risk factors, and ... It is the most frequent anatomic disease of the colon. Costs associated with diverticular disease were around US $2.4 billion a ... Right-sided diverticula are micro-hernias of the colonic mucosa and submucosa through the colonic muscular layer where blood ...

https://en.wikipedia.org/wiki/Diverticulitis

Micro perforations with free air may be seen.[citation needed] Ulcerative colitis or Crohn's disease may cause colonic ... It has been associated to several diseases, including Huntington's disease. Laparotomy for other forms of volvulus, especially ... Although diverticulitis may be the source of a colonic obstruction, it more commonly causes an ileus, which appears to be a ... The medical history is helpful in that most cases of inflammatory bowel disease are well known to both patient and doctor. ...

https://en.wikipedia.org/wiki/Volvulus

Maladie d'Arbuthnot Lane)" [Colonic inertia and rectal obstruction (Arbuthnot Lane disease)]. Annales de Gastroentérologie et ... The syndrome that Lane reported in 1908, "Lane disease" or "Arbuthnot Lane disease", is now usually termed by ... "Lane's disease"-now otherwise termed colonic inertia, which he identified in 1908-which surgeries were controversial but ... Tracing diverse diseases to modern civilization, he urged the people to return to farmland. For his New Health, Lane eventually ...

https://en.wikipedia.org/wiki/Sir_William_Arbuthnot_Lane,_1st_Baronet

"Intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease". World Journal of ... Thus, altered IAP expression has been implicated in chronic inflammatory diseases such as inflammatory bowel disease (IBD). It ... Some diseases do not affect the levels of alkaline phosphatase, for example, hepatitis C. A high level of this enzyme does not ... Placental alkaline phosphatase is elevated in seminomas and active forms of rickets, as well as in the following diseases and ...

https://en.wikipedia.org/wiki/Alkaline_phosphatase

Large intestine: nonspecific ulcerative colitis, Crohn's disease, chronic colitis, colonic polyps, colorectal cancer, etc. The ... The laparoscopy: liver disease, biliary disease, etc. The respiratory tract: lung cancer, transbronchoscopy lung biopsy, ... Laparoscope was used in the diagnosis of liver and gallbladder disease by Heinz Kalk in the 1930s. Hope reported in 1937 on the ... It is meeting a growing demand to lessen the risk of cross contamination and hospital acquired diseases. A European consortium ...

https://en.wikipedia.org/wiki/Endoscope

"Colonic Biopsies to Assess the Neuropathology of Parkinson's Disease and Its Relationship with Symptoms". PLOS ONE. 5 (9): ... researchers have been using colonic biopsies of Parkinson's patients to help better understand and manage Parkinson's disease. ... Hirschsprung's disease is a congenital disorder of the colon in which nerve cells of the myenteric plexus in its walls, also ... Hirschsprung's disease is a form of functional low bowel obstruction due to failure of caudal migration of neuroblasts within ...

https://en.wikipedia.org/wiki/Myenteric_plexus

Functional colonic diseases refer to disorders without a known cause, including irritable bowel syndrome and intestinal ... Gastrointestinal diseases (abbrev. GI diseases or GI illnesses) refer to diseases involving the gastrointestinal tract, namely ... Other causes of chronic liver disease are genetic or autoimmune disease, such as hemochromatosis, Wilson's disease, autoimmune ... Liver disease may also be a result of lifestyle factors, such as fatty liver and NASH. Alcoholic liver disease may also develop ...

https://en.wikipedia.org/wiki/Gastrointestinal_disease

Colonoscopy is necessary in colonic and ileal disease. ERCP will show pancreatic and biliary structural abnormalities. 75SeHCAT ... OGD to detect duodenal pathology and obtain D2 biopsy (for coeliac disease, tropical sprue, Whipple's disease, ... as occurs in coeliac disease with extensive involvement of the small intestine. Depending on the nature of the disease process ... For example, pain is common in patients with chronic pancreatitis or pancreatic cancer and Crohn's disease, but it is absent in ...

https://en.wikipedia.org/wiki/Malabsorption

It is used to treat inflammatory bowel disease, including ulcerative colitis and Crohn's disease (effective only in colonic ... including ulcerative colitis and Crohn's disease. It is generally used for mildly to moderately severe disease. It is taken by ... The drug should not be used in children under two years of age, people with kidney disease, or people who are allergic to ... It is in the category of disease-modifying antirheumatic drugs (DMARDs) family of medications. It is unclear exactly how it ...

https://en.wikipedia.org/wiki/Mesalazine

Humes D, Smith JK, Spiller RC (14 March 2011). "Colonic diverticular disease: medical treatments for acute diverticulitis". BMJ ... "Clinical manifestations and diagnosis of colonic diverticular disease". Literature review. Stefánsson T, Ekbom A, Sparèn P, ... Diverticular disease was found associated with a higher risk of left sided colon cancer. Diverticular disease can present with ... Pemberton, John H (16 June 2016). "Colonic diverticulosis and diverticular disease: Epidemiology, risk factors, and ...

https://en.wikipedia.org/wiki/Diverticulosis

Schofield, P. F.; Jones, D. J. (1992). "ABC of colorectal diseases. Colorectal neoplasia-I: Benign colonic tumours". BMJ ( ... Colonic resection may be required for large lesions. These can also lead to secretory diarrhea with large volume liquid stools ...

https://en.wikipedia.org/wiki/Colorectal_adenoma

Bitterness and Colonic Neoplasms". Digestive Diseases and Sciences. 50 (3): 483-9. doi:10.1007/s10620-005-2462-7. PMID 15810630 ...

https://en.wikipedia.org/wiki/Supertaster

... a certain level of control is required for effective and safe treatment of colonic diseases. The L. lactis system has a 72-hour ... During clinical trials, it has been used to treat forms of inflammatory bowel disease (IBD). The most prominently studied ... implemented microbial drug delivery with L. lactis in clinical trials, successfully treating Crohn's disease (CD), a form of ... "A Phase I Trial With Transgenic Bacteria Expressing Interleukin-10 in Crohn's Disease". Clinical Gastroenterology and ...

https://en.wikipedia.org/wiki/Microbial_drug_delivery

... and total colonic Hirschsprung's disease. An ileostomy may also be necessary in the treatment of colorectal cancer or ovarian ... Diseases of the large intestine which may require surgical removal include Crohn's disease, ulcerative colitis, familial ... In some patients with Crohn's disease, a procedure called an ileoanal anastomosis is done if the disease affects the entire ... 2003), "Surgery for inflammatory bowel diseases", Dig. Dis. 21(2):168-79. "Colorectal Diseases and Treatments". ASCRS. Archived ...

https://en.wikipedia.org/wiki/Ileostomy

The report stated that the measles virus was responsible for the colonic lesions seen in Crohn's disease, however, this theory ... Vaccines can cause the same disease that one is vaccinated against: A vaccine causing complete disease is extremely unlikely. ... These are: threat of disease (vaccine preventable diseases are harmless), trust (questioning the trustworthiness of healthcare ... More so over, when infected, they can then transfer the disease to a person who is immunocompromised. This not only harms ...

https://en.wikipedia.org/wiki/Vaccine_misinformation

Several factors may influence the development of the disease, such as local colonic ischemia, fecal stasis, or mucosal prolapse ... "Diverticular disease associated with inflammatory bowel disease-like colitis: a systematic review". Diseases of the Colon and ... Sladen, GE; Filipe, MI (August 1984). "Is segmental colitis a complication of diverticular disease?". Diseases of the Colon and ... is it the coexistence of colonic diverticulosis and inflammatory bowel disease?". Annals of Gastroenterology. 30 (3): 257-261. ...

https://en.wikipedia.org/wiki/Segmental_colitis_associated_with_diverticulosis

... a greater number than those with inflammatory bowel disease such as Crohn's disease or ulcerative colitis. New agents have been ... is important as many cancer survivors of radiation therapy develop other causes for their symptoms such as colonic polyps, ... Min M, Chua B, Guttner Y, Abraham N, Aherne NJ, Hoffmann M, McKay MJ, Shakespeare TP (2014). "Is "pelvic radiation disease" ... Stacey R, Green JT (2014). "Radiation-induced small bowel disease: latest developments and clinical guidance". Ther Adv Chronic ...

https://en.wikipedia.org/wiki/Radiation_enteropathy

... to a Western diet lower in fibre in rising frequencies of appendicitis as well as the other aforementioned colonic diseases in ... "Pelvic inflammatory disease (PID) Symptoms; Diseases and Conditions". Mayo Clinic. Archived from the original on 2015-05-07. ... Diverticular disease and adenomatous polyps was historically unknown and colon cancer was exceedingly rare in communities where ... "WHO Disease and injury country estimates". World Health Organization. 2009. Archived from the original on 11 November 2020. ...

https://en.wikipedia.org/wiki/Appendicitis

... cardiovascular diseases, pulmonary diseases, bone diseases, liver diseases, colonic diseases, infections, and HIV. Although ... Dextran prodrugs have potential applications in the treatment of liver diseases, pulmonary diseases, colonic diseases, and ... colonic diseases, bone diseases, and cardiovascular diseases. Dextran micelles are 10 to 100 nm sized amphiphilic polymeric ... Dextran-based drug delivery systems have an enormous potential for clinical use in the treatment of a variety of disease states ...

https://en.wikipedia.org/wiki/Dextran_drug_delivery_systems

Scholia has a topic profile for Colonic ulcer. v t e v t e (Abdominal pain, All stub articles, Disease stubs, Digestive system ... Colonic ulcer can occur at any age, in children however they are rare. Most common symptoms are abdominal pain and hematochezia ... Maire, F.; Cellier, C.; Cervoni, J. P.; Danel, C.; Barbier, J. P.; Landi, B. (November 1998). "[Dieulafoy colonic ulcer. A rare ... Large intestine Kleinman, Ronald E. (1998). Atlas of Pediatric Gastrointestinal Disease. PMPH-USA. p. 209. ISBN 978-1-55009-038 ...

https://en.wikipedia.org/wiki/Colonic_ulcer

... dendritic cell populations in the colonic mucosa of patients with Crohn's disease". European Journal of Immunology. 33 (1): 143 ...

https://en.wikipedia.org/wiki/CD83

... has been proposed as the ultimate cause of both ulcerative colitis and Crohn's disease. An increased amount of colonic sulfate- ... Human colonic mucosa is maintained by the colonic epithelial barrier and immune cells in the lamina propria (see intestinal ... The most common disease that mimics the symptoms of ulcerative colitis is Crohn's disease, as both are inflammatory bowel ... Adequate disease control usually improves anemia of chronic disease, but iron deficiency anemia should be treated with iron ...

https://en.wikipedia.org/wiki/Ulcerative_colitis

The antibiotics Metronidazole and ciprofloxacin may be used to treat Crohn's disease with colonic or perianal involvement, ... What should patients with Crohn's disease avoid?, from Inflammatory Bowel Disease Program at the Digestive Disease Center at ... If a Crohn's disease patient who undergoes surgery does not quit smoking, the disease is likely to recur more aggressively. In ... Management of Crohn's disease involves first treating the acute symptoms of the disease, then maintaining remission. Since ...

https://en.wikipedia.org/wiki/Management_of_Crohn's_disease

Colonic emptying after transanal irrigation Bazzocchi G, Poletti E, Pillastrini Christensen, P; Krogh, K; Buntzen, S; Payandeh ... Diseases of the Colon and Rectum. 46 (1): 68-76. doi:10.1007/s10350-004-6498-0. PMID 12544524. S2CID 32754686. Christensen, ... Christensen, P; Olsen, N; Krogh, K; Bacher, T; Laurberg, S (Jan 2003). "Scintigraphic assessment of retrograde colonic washout ... Diseases of the Colon and Rectum. 52 (2): 286-92. doi:10.1007/DCR.0b013e3181979341. PMID 19279425. S2CID 24381352. ...

https://en.wikipedia.org/wiki/Transanal_irrigation

Multinodular disease was representedby nodular colonic lesions and pseudokidney appearances, while the single-nodular Dapaong ... GIDEON Infectious Diseases - Diseases (oesophagostomiasis). GIDEON Infectious Disease Database. 5 Feb 2009. Sun, Tsieh. ... Single-nodular disease, more commonly known as Dapaong disease, is characterized by the development of a single mass that ... Oesophagostomiasis is generally classified as a zoonotic disease, which is an infectious disease that can be transmitted ...

https://en.wikipedia.org/wiki/Oesophagostomum

... and recurrent respiratory papillomatosis DRB1*0103 is associated with colonic Crohn's disease and ulcerative colitis. DRB1*0101 ... In lyme disease arthritis, *0101 appears to play a role in presentation of triggering microbial antigens. DRB1*0102 is ... Swiss Federal Commission for the Rheumatic Diseases, Subcommission for Research". Rheumatol Int. 6 (2): 89-92. 1986. doi: ... and disease severity in patients with recurrent respiratory papillomatosis". Hum Immunol. 65 (8): 773-782. doi:10.1016/j.humimm ...

https://en.wikipedia.org/wiki/HLA-DR1

... pancreas and liver and the role of pathogens and food toxins in various diseases. His work on veno-occlusive disease of the ... "Diagnosis of ileocecal and colonic tuberculosis by colonoscopy". Gastrointestinal Endoscopy. 31 (2): 68-70. doi:10.1016/S0016- ... and is the incumbent chair of the Digestive Diseases Foundation of India and the Digestive Diseases Research Foundation. He has ... He served as the chairman of the Task Force of Liver Diseases initiated by the Indian Council of Medical Research (ICMR) ...

https://en.wikipedia.org/wiki/Badri_Nath_Tandon

In 1996, Wexner and colleagues released a method of scoring perianal disease activity for patients with Crohn's Disease. The ... He also popularized the colonic j-pouch for patients with rectal cancer. The J-pouch, an alternative to a permanent ileostomy ... was ranked as the most cited paper on benign anorectal disease. On October 19, 2021, Elsevier published a list of the top cited ... 2006). Diverticular Disease: Emerging Evidence in Common Conditions, 1st ed. Springer. ISBN 1849968969 Steven D. Wexner, Andrew ...

https://en.wikipedia.org/wiki/Steven_D._Wexner

Inflammatory Bowel Disease); particularly Crohn's Disease and Ulcerative Colitis and regressive behavioural disease (RBD) (also ... unremarkable colonic histopathology results-noting no or minimal fluctuations in inflammatory cell populations-were changed ... These childhood diseases can do real damage, so we're proud to be an organisation that gets the good news out there - the ... The Times reported in May 2010 that he was a medical advisor for Visceral, a UK charity that "researches bowel disease and ...

https://en.wikipedia.org/wiki/Andrew_Wakefield

... familial nonpolyposis Colonic atresia Colonic malakoplakia Color blindness Colorado tick fever Colver-Steer-Godman syndrome ... Marie-Tooth disease type 1A Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease type 1C Charcot-Marie-Tooth disease ... Marie-Tooth disease type 2C Charcot-Marie-Tooth disease type 2D Charcot-Marie-Tooth disease type 4A Charcot-Marie-Tooth disease ... Tooth disease Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease deafness dominant type Charcot-Marie-Tooth disease ...

https://en.wikipedia.org/wiki/List_of_diseases_(C)

... and pancreatic disease The primary side effects of the drug are gastrointestinal-related, and include steatorrhea (oily, loose ... "The anti-obesity agent Orlistat is associated to increase in colonic preneoplastic markers in rats treated with a chemical ... which is based on a list of easily diagnosable diseases. U.S. patent protection for Xenical, originally to end on 18 June 2004 ...

https://en.wikipedia.org/wiki/Orlistat

Digestive Diseases (Basel, Switzerland). 38 (1): 15-22. doi:10.1159/000502055. PMID 31408875. S2CID 199573818. Kim, HW (May ... "CT findings of post-polypectomy coagulation syndrome and colonic perforation in patients who underwent colonoscopic polypectomy ...

https://en.wikipedia.org/wiki/Postpolypectomy_coagulation_syndrome

Colonic spirochetes: an infrequent cause of adult diarrhea]". Gastroenterol Hepatol (in Spanish). 27 (1): 21-3. doi:10.1016/ ... porcine intestinal spirochaetosis is an economically important disease of livestock. No clear association exists with ... is an infection of the colonic-type mucosa with certain species of spirochetal bacteria. Similar infections sometimes occur in ...

https://en.wikipedia.org/wiki/Intestinal_spirochetosis

However, bovine respiratory disease, the most common reason for antibiotic therapy, has risk factors common in both forms of ... "Influence of Diet on Total and Acid Resistant E. coli and Colonic pH" (PDF). 2000 Nebraska Beef Report: 39-41. Archived from ... Since only a tiny amount of the contaminating prion begins the cascading brain disease, any amount of mixed feed could cause ... Because of their effectiveness in the treatment and prevention of diseases, there is an increased efficiency of the farm. This ...

https://en.wikipedia.org/wiki/Cattle_feeding

Butyrate also possesses anti-inflammatory effects to decrease colonic inflammation such as ulcerative colitis. One study ... implications for Crohn's disease". Gut. 47 (3): 397-403. doi:10.1136/gut.47.3.397. PMC 1728045. PMID 10940278. Hartmanis MG ( ... it is hypothesized that butyrate can act as a protective agent against colon cancer and various inflammatory bowel diseases. ... "Rationale for the luminal provision of butyrate in intestinal diseases". European Journal of Nutrition. 39 (4): 164-71. doi: ...

https://en.wikipedia.org/wiki/Butyrate_kinase

Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: ... as well as a wide range of other pathogenic states classifiable in general as colonic escherichiosis. While E. coli is ... Disease-a-Month. 49 (2): 71-82. doi:10.1067/mda.2003.8. PMID 12601338. "The Species of Escherichia other than E. coli". The ... other members of the genus have also been implicated in human disease. Escherichia are associated with the imbalance of ...

https://en.wikipedia.org/wiki/Escherichia

Certain diseases and conditions are caused by functional defects in the intestinal epithelium. On the other hand, various ... Geibel, John P. (1 January 2005). "Secretion and absorption by colonic crypts". Annual Review of Physiology. 67: 471-490. doi: ... Loss of integrity of the intestinal epithelium plays a key pathogenic role in inflammatory bowel disease (IBD). Changes in the ... IBD is a multifactorial disease that is nonetheless driven in part by an exaggerated immune response to gut microbiota that ...

https://en.wikipedia.org/wiki/Intestinal_epithelium

There he was responsible for performing autopsies on patients who had died of pulmonary diseases. In 1940, a job in pathology ... In mid-1993, Ackerman developed abdominal complaints and was found to have peritoneal carcinomatosis from a colonic cancer. He ...

https://en.wikipedia.org/wiki/Lauren_Ackerman

A section of his Carcinoma of the Rectum was reprinted in 1986 as part of a series of "Classic Articles of Colonic and Rectal ... 1880 On Diseases of the Rectum and Anus - 1884 The Passage of Air and Faeces from the Urethra - 1888 Ovariotomy and Abdominal ... 1364 Diseases of the Colon & Rectum 1986; 29: p. 534-541 "William Harrison Cripps, F.R.C.S.", British Medical Journal, November ... Surgery" in the journal Diseases of the Colon & Rectum. In a contribution appended to Cripps' obituary in the British Medical ...

https://en.wikipedia.org/wiki/William_Harrison_Cripps

"Probable Link Evaluation for heart disease (including high blood pressure, high cholesterol, coronary artery disease)" (PDF). ... of hydrogen sulfide result which reduce beta-oxidation and thus nutrient production leading to a breakdown of the colonic ... In 2018 White House staff and EPA pressured the U.S. Agency for Toxic Substances and Disease Registry to suppress a study that ... Centers for Disease Control and Prevention. September 2, 2021. Retrieved October 10, 2021. "New Report Calls for Expanded PFAS ...

https://en.wikipedia.org/wiki/Per-_and_polyfluoroalkyl_substances

Gibson GR, Roberfroid MB (1995). "Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics". J ... Digestive Diseases and Sciences. 58 (1): 23-32. doi:10.1007/s10620-012-2334-x. PMC 3557374. PMID 22903218. Pineiro M, et al. ( ...

https://en.wikipedia.org/wiki/Synbiotics

Liu M, Yokomizo T (2015). "The role of leukotrienes in allergic diseases". Allergology International. 64 (1): 17-26. doi: ... is aberrantly expressed in colonic cancers". Carcinogenesis. 19 (1): 49-53. doi:10.1093/carcin/19.1.49. PMID 9472692. Coleman ... Fumagalli M, Lecca D, Abbracchio MP (2016). "CNS remyelination as a novel reparative approach to neurodegenerative diseases: ... Matsuoka T, Narumiya S (2007). "Prostaglandin receptor signaling in disease". TheScientificWorldJournal. 7: 1329-47. doi: ...

https://en.wikipedia.org/wiki/Eicosanoid_receptor

Division of Parasitic Diseases, Centers for Disease Control and Prevention. Archived from the original on 27 November 2013. ... where they attach themselves to the mucosa and ingest colonic contents. Almost the entire body of a gravid female becomes ... In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. ... ISBN 978-0-19-512143-8. Cook, Gordon C; Zumla, Alimuddin I (2009). Manson's tropical diseases (22nd ed.). Saunders Elsevier. pp ...

https://en.wikipedia.org/wiki/Pinworm_(parasite)

Similar to CVD, post-menopausal women have an increased risk of developing Alzheimer's disease (AD) due to a loss of estrogen, ... ERβ is expressed by many tissues including the uterus, blood monocytes and tissue macrophages, colonic and pulmonary epithelial ... Li R, Cui J, Shen Y (May 2014). "Brain sex matters: estrogen in cognition and Alzheimer's disease". Molecular and Cellular ... In old female ERβ knockout mice, severe cystic mammary disease that is similar in appearance to postmenopausal mastopathy ...

https://en.wikipedia.org/wiki/Estrogen_receptor_beta

Such injury could be the result of infection, celiac disease, inflammatory bowel disease, or other diseases. Developmental ... Regular consumption of dairy food by lactase deficient individuals may also reduce symptoms of intolerance by promoting colonic ... Physicians should investigate the presence of undiagnosed coeliac disease, Crohn disease, or other enteropathies when secondary ... It may be caused by acute gastroenteritis, coeliac disease, Crohn's disease, ulcerative colitis, chemotherapy, intestinal ...

https://en.wikipedia.org/wiki/Lactose_intolerance

cite journal}}: Cite journal requires ,journal= (help) Ladas, S. D.; Karamanolis, G.; Ben-Soussan, E. (2007). "Colonic gas ... Journal of Wildlife Diseases. 57 (2): 357-367. doi:10.7589/2019-08-202. ISSN 0090-3558. PMID 33822147. S2CID 232357722. "2022 ... or Pasteur's theory that germs cause disease. Sociology - Presented to Steve Penfold, of York University in Toronto, for doing ... "A novel non-invasive tool for disease surveillance of free-ranging whales and its relevance to conservation programs". Animal ...

https://en.wikipedia.org/wiki/List_of_Ig_Nobel_Prize_winners

... have been linked to this disease. In an inbred Israeli Bedouin family, the mutations, inherited in an autosomal recessive ... "Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis". Molecular and Cellular ...

https://en.wikipedia.org/wiki/UQCRQ

Wang Y, Bi L, Wang H, Li Y, Di Q, Xu W, Qian Y (2012). "NEDD9 rs760678 polymorphism and the risk of Alzheimer's disease: a meta ... promotes colonic cell migration and cancer progression". Oncogene. 30 (23): 2633-43. doi:10.1038/onc.2010.632. PMC 3164309. ... Nikonova AS, Gaponova AV, Kudinov AE, Golemis EA (2014). "CAS proteins in health and disease: an update". IUBMB Life. 66 (6): ... "Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease" (Oncoscience ...

https://en.wikipedia.org/wiki/NEDD9

Gold JS, Bayar S, Salem RR (July 2004). "Association of Streptococcus bovis bacteremia with colonic neoplasia and extracolonic ... List of oncogenic bacteria Infectious causes of cancer List of human diseases associated with infectious pathogens Oncovirus ... ISBN 978-0-8147-3562-6. L'esperance ES (January 1931). "Studies in Hodgkin's Disease". Annals of Surgery. 93 (1): 162-168. doi: ... "An experimental biologic approach to the treatment of neoplastic disease; determination of actinomycin in urine and cultures as ...

https://en.wikipedia.org/wiki/Carcinogenic_bacteria

Diseases associated with CCL7 dysregulation are observed. For example, an abnormal increase of CCL7 worsens many disorders, ... "Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells". The Journal of Clinical Investigation. ... Ouchi N, Parker JL, Lugus JJ, Walsh K (February 2011). "Adipokines in inflammation and metabolic disease". Nature Reviews. ... Furthermore, CCL7 is implicated in various immunological diseases, as ulcerative colitis, multiple sclerosis or nonatopic and ...

https://en.wikipedia.org/wiki/CCL7

The first human disease known to be associated with miRNA deregulation was chronic lymphocytic leukemia. Many other miRNAs also ... but not in sporadic colonic adenocarcinoma that lack mucinous components. In-vitro studies suggested that miR-205 and miR-373 ... The first human disease associated with deregulation of miRNAs was chronic lymphocytic leukemia. In this disorder, the miRNAs ... According to the Center for Disease Control and Prevention, Stroke is one of the leading causes of death and long-term ...

https://en.wikipedia.org/wiki/MicroRNA

Alterations in Colonic Anatomy Induced by Chronic Stimulant Laxatives: The Cathartic Colon Revisited Joo et al. Journal of ... National Digestive Diseases Information Clearinghouse. Retrieved 3 November 2014. Bulk-forming agent entry in the public domain ... 1, 2012 Joo JS, Ehrenpreis ED, Gonzalez L, Kaye M, Breno S, Wexner SD, Zaitman D, Secrest K (1998). "Alterations in colonic ... Joo JS, Ehrenpreis ED, Gonzalez L, Kaye M, Breno S, Wexner SD, Zaitman D, Secrest K (June 1998). "Alterations in colonic ...

https://en.wikipedia.org/wiki/Laxative

Early-stage disease does not need to be treated. CLL and SLL are considered the same underlying disease, just with different ... Colonic perforation secondary to chronic lymphocytic leukemia infiltration without Richter transformation. Leuk Lymphoma. 2011 ... Approximately 3,200 people were diagnosed with the disease in 2011. In Western populations, subclinical "disease" can be ... The disease most commonly occurs in people over the age of 65, due to the accumulation of genetic mutations that occurs over ...

https://en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

Health Information on Colonic Diseases: MedlinePlus Multiple Languages Collection ... Colonic Diseases: MedlinePlus Health Topic - English Enfermedades del colon: Tema de salud de MedlinePlus - español (Spanish) ... URL of this page: https://medlineplus.gov/languages/colonicdiseases.html Other topics A-Z. ...

https://medlineplus.gov/languages/colonicdiseases.html

Invasive Colonic Entamoebiasis in Wild Cane Toads, Australia. Emerging Infectious Diseases. 2018;24(8):1541-1543. doi:10.3201/ ... Invasive colonic entamoebiasis in wild cane toads (Rhinella marina), tropical Australia, 2014-2015. A) Toad with severe colonic ... Invasive colonic entamoebiasis in wild cane toads (Rhinella marina), tropical Australia, 2014-2015. A) Toad with severe colonic ... The disease outbreak involved conspicuous behavior, severe clinical disease, and high mortality. Populations of invasive ...

https://wwwnc.cdc.gov/eid/article/24/8/18-0101

Suppressed Rac1 signaling in non-inflamed colonic mucosa of Crohns disease patients has been shown to correlate with increased ... RESULTS:Macrophage infiltration and Rac1 signaling was increased in inflamed mucosal tissues of Crohns disease patients. ... Inhibiting Rac1 activation may be crucial for optimizing macrophage immunity for treatment of Crohns disease. ... on Rac1 signaling in macrophages and mucosal tissue samples collected from 10 patients with active Crohns disease and further ...

https://medscimonit.com/abstract/related/idArt/910266

The colonic drug delivery is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, ... Crohns disease, ameabiosis, colonic cancer, and systemic delivery of many drugs which degrades in stomach and small intestine ... Colon is the distal organ of the GIT, hence difficulty arises in colonic drug delivery. However there are many techniques for ... The colonic drug delivery is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, ...

https://zenodo.org/record/2526037

Long-term risk of cardiovascular and cerebrovascular disease after removal of the colonic microbiota by colectomy: a cohort ... Long-term risk of cardiovascular and cerebrovascular disease after removal of the colonic microbiota by colectomy: a cohort ...

https://bmjopen.bmj.com/content/5/12/e008702.altmetrics

Patients and methods: The mucosa associated colonic microflora of 57 patients with active inflammatory bowel disease and 46 ... Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease ... Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease ... Diversity of the microflora in Crohns disease was reduced to 50% compared with controls (21.7 v 50.4; p,0.0001) and to 30% in ...

https://gut.bmj.com/content/53/5/685.abstract

Crohn disease is a chronic inflammatory bowel disease. Once considered rare in the pediatric population, it is recognized with ... Colonic Crohn disease. Colonic Crohn disease may be clinically indistinguishable from ulcerative colitis (UC), with symptoms of ... Colonic malignancy is a clinically significant complication of Crohn disease in patients with pancolitis beginning in childhood ... Colonic granuloma in patient with Crohn disease. Hematoxylin-eosin staining. Image courtesy of Dr E Ruchelli. ...

https://www.medscape.com/answers/928288-180311/what-are-common-presenting-symptoms-of-pediatric-crohn-disease

Colonic diverticular disease: current perspectives. Journal of the Nepal Medical Association. 2007 Oct-Dec; 46(168): 206-13. ... Complicated colonic diverticular disease (CDD) is associated with significant morbidity and mortality. Increasing urbanisation ... Diverticular disease is a common condition affecting large intestine in the western world, which, although remains asymptomatic ... and current management of diverticular disease of the colon and its complications. ...

https://imsear.searo.who.int/handle/123456789/45882

This could possibly affect epithelial repair as several of these bacterial metabolites are known to inhibit colonic epithelial ... after disease onset, typically progress in two cyclically repeated phases, namely inflammatory flare and remission, with ... of dietary protein consumption and amino acid supplementation may differently influence the IBD course according to the disease ... Dietary Protein and Amino Acid Supplementation in Inflammatory Bowel Disease Course: What Impact on the Colonic Mucosa? Sandra ...

https://hal-agroparistech.archives-ouvertes.fr/hal-01568606

Risankizumab more efficacious in colonic than in ileal Crohns disease. Presented By. Dr Peter Bossuyt, Imelda General Hospital ... Risankizumab more efficacious in colonic than in ileal Crohns disease. Presented By. Dr Peter Bossuyt, Imelda General Hospital ... the efficacy of this therapy regarding disease location has not yet been investigated. "And we know that disease location may ... Risankizumab more efficacious in colonic than in ileal Crohns disease ...

https://dev.mc.sense-studios.com/specialisation/gastroenterology/risankizumab-more-efficacious-in-colonic-than-in-ileal-crohns-disease/

https://wwwnc-origin.cdc.gov/eid/article/24/8/18-0101

Crohns disease; Colitis; Mesalazine; 5-ASA; Inflammatory bowel disease; Endoscopy; Enfermedad de Crohn; Colitis; Mesalazina; 5 ... Clinical and endoscopic outcomes of patients with colonic Crohns disease treated with 5-aminosalicylates as monotherapy / ... Clinical and endoscopic outcomes of patients with colonic Crohns disease treated with 5-a ... compounds in Crohns disease (CD), these drugs are frequently used in daily clinical practice, particularly for colonic CD. Our ...

https://pesquisa.bvsalud.org/portal/resource/pt/ibc-217438

Colonic Diseases*. Rectal Diseases. Publication Type(s):. Periodical. NLM ID:. 101540645 [Serial]. ...

https://www.ncbi.nlm.nih.gov/nlmcatalog/?term=2073-7556

In vivo colonic transit was evaluated by radiological assay. Electrically and carbachol-induced cholinergic contractions were ... In vivo colonic transit was evaluated by radiological assay. Electrically and carbachol-induced cholinergic contractions were ... Parkinsons disease (PD) is frequently associated with gastrointestinal symptoms, mostly represented by constipation and ... As compared with control rats, at week 4 6-OHDA-treated animals displayed the following changes: decreased in vivo colonic ...

https://air.unipr.it/handle/11381/2797588

Colonic Diseases, Functional / diagnosis * Colonic Diseases, Functional / drug therapy* * Colonic Diseases, Functional / ... b) For the cyclic and non-life-threatening nature of the disease, a long-term study of 4-6 months or more of active treatment ...

https://pubmed.ncbi.nlm.nih.gov/12969083/?dopt=Abstract

Anorectal and Colonic Diseases. Givel, Jean-Claude R.. 273,90€. Fecal Incontinence. Doglietto, Giovanni B. ...

https://www.ellibs.com/book/9781848009059/transanal-stapling-techniques-for-anorectal-prolapse

Digestive System Diseases. Colonic Diseases. Intestinal Diseases. Pathologic Processes. Inflammatory Bowel Diseases. Golimumab ... A score of 3 to 5 points indicates mildly active disease; a score of 6 to 10 indicates moderately active disease; and a score ... A score of 3 to 5 points indicates mildly active disease; a score of 6 to 10 indicates moderately active disease; and a score ... A score of 3 to 5 points indicates mildly active disease; a score of 6 to 10 indicates moderately active disease; and a score ...

https://www.clinicaltrials.gov/ct2/show/NCT03596645

Digestive System Diseases. Colonic Diseases. Intestinal Diseases. Pathologic Processes. Inflammatory Bowel Diseases. Prednisone ... assessed by disease activity index (DAI) and simple activity index. *Proportion of patients with corticodependency criteria [ ... uncompleted disease remission after CS use, that is, clinical but not endoscopic remission, has been associated with a higher ... a survey of the Japanese Society for Pediatric Inflammatory Bowel Disease. Digestion. 2010;81(3):188-92. doi: 10.1159/000255379 ...

https://clinicaltrials.gov/ct2/show/NCT02921555

Drugs for Colonic Disease. 1:00 pm. Graduate School Info Session. 4:00 pm ...

https://uh.edu/calendar/?d=27&m=04&y=2022&view=m

... chronic ischaemic heart disease, cardiac arrhythmias, heart failure, cerebrovascular diseases and other arterial diseases) and ... chronic ischaemic heart disease, cardiac arrhythmias, heart failure, cerebrovascular diseases and other arterial diseases) and ... chronic ischaemic heart disease, cardiac arrhythmias, heart failure, cerebrovascular diseases and other arterial diseases) and ... chronic ischaemic heart disease, cardiac arrhythmias, heart failure, cerebrovascular diseases and other arterial diseases) and ...

https://scholars.mssm.edu/en/publications/long-term-risk-of-cardiovascular-and-cerebrovascular-disease-afte-2

... primary sclerosing cholangitis does not increase the risk for colorectal dysplasia in patients with colonic Crohns disease ... primary sclerosing cholangitis does not increase the risk for colorectal dysplasia in patients with colonic Crohns disease ...

https://www.expmedndm.ox.ac.uk/publications/171762

Although ulcerative colitis (UC) is a major type of inflammatory bowel disease, attempts to model it fully have fallen short. ... Here the authors use patient-derived iPS cells to develop a UC organoid model that recapitulates disease histological and ... a major type of inflammatory bowel disease, remains unknown. No model exists that adequately recapitulates the complexity of ... Colonic epithelial cell diversity in health and inflammatory bowel disease. Nature 567, 49-55 (2019). ...

https://www.nature.com/articles/s41467-020-20351-5?error=cookies_not_supported&code=65aae6df-87ca-43c5-bf66-c7cc66530e0d

Lactobacillus paracasei CNCM I 1572: A promising candidate for management of colonic diverticular disease.Mar 29, 2022. ... Diseases : Cancers: All, Cardiovascular Diseases, Edema, Gastrointestinal Diseases, Inflammation, Metabolic Diseases. ... Diseases : Anxiety, Dental Caries, Depression, Gastrointestinal Diseases, Periodontal Diseases. Pharmacological Actions : ... Diseases : Celiac Disease, Colorectal Cancer, Colorectal Cancer: Prevention , Gastrointestinal Diseases. Pharmacological ...

https://greenmedinfo.com/disease/gastrointestinal-diseases

... in people with neurological diseases, summarizing recent correlative and causative evidence in the scientific literature and ... 2015). Colonic bacterial composition in Parkinsons disease. Mov. Disord. 30, 1351-1360. doi: 10.1002/mds.26307 ... 2017). Parkinsons disease and Parkinsons disease medications have distinct signatures of the gut microbiome. Mov. Disord. 32 ... Parkinsons disease is the second most common neurodegenerative disorder of aging (Disease et al., 2016), it results primarily ...

https://www.frontiersin.org/articles/10.3389/fnins.2022.946601/full

Colonic inflammation in Parkinsons disease. Neurobiol Dis. 2012 Sep 24;50C:42-48. PubMed. ...

https://www.alzforum.org/papers/colonic-inflammation-parkinsons-disease

Categories: Colonic Diseases Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 5 ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ...

https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Colonic+Diseases&parentid=14283&catid=6750

Colonic Diseases (2). Constipation (2). Crohns Disease (2). Diabetes (6). Diabetes Medicines (1) ...

https://effectivehealthcare.ahrq.gov/products/search?f%5B0%5D=field_product_agency.tid:8147&f%5B1%5D=field_product_agency.tid:8127&f%5B2%5D=field_product_agency.tid:8117&f%5B3%5D=field_product_doc_status.tid:10874&f%5B4%5D=field_product_agency.tid:8118&f%5B5%5D=field_product_agency.tid:8098

Colonic Diseases (1). Digestive Diseases (1). Falls (1). Medicaid (1). Pain Relievers (1) ...

https://effectivehealthcare.ahrq.gov/products/search?f%5B0%5D=field_product_agency.tid:8139&f%5B1%5D=field_research_method.tid:25&f%5B2%5D=field_product_agency.tid:8096&f%5B3%5D=field_product_agency.tid:8137&f%5B4%5D=field_product_agency.tid:8144&f%5B5%5D=field_product_agency.tid:8106

Obesity, physical inactivity, and colonic diverticular disease requiring hospitalization in women: a prospective cohort study ... Communicable Diseases *Transmission of norovirus among NBA players and staff, Winter 2010-2011external icon. Desai R, Yen C, ... Disease Reservoirs and Vectors *Spotted fever group rickettsiae in ticks collected from wild animals in Israelexternal icon ... Chronic Diseases and Conditions *Melanoma surveillance in the United States: overview of methodsexternal icon. Watson M, ...

https://www.cdc.gov/library/sciclips/issues/v3issue45.html

The colonic drug delivery is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, Crohn's disease, ameabiosis, colonic cancer, and systemic delivery of many drugs which degrades in stomach and small intestine, such as proteins and peptides. (zenodo.org)
Colonic Crohn disease may be clinically indistinguishable from ulcerative colitis (UC), with symptoms of bloody mucopurulent diarrhea, cramping abdominal pain, and urgency to defecate (see the Table below). (medscape.com)
The pathogenesis of ulcerative colitis (UC), a major type of inflammatory bowel disease, remains unknown. (nature.com)
Ulcerative colitis (UC) is one of the two principal types of inflammatory bowel disease (IBD) and is a debilitating inflammatory condition of the colon that usually begins in young adulthood 1 . (nature.com)
Many treatments for inflammatory bowel diseases (IBDs), such as ulcerative colitis, are delivered directly into the bloodstream and cause severe short- or long-term side effects. (scienceboard.net)
52% of Ulcerative Colitis (UC) patients who have an active disease are included in this statistic. (maunakeatech.com)
Confocal laser endomicroscopy in ulcerative colitis: beyond endoscopic assessment of disease activity. (maunakeatech.com)
2021. Transferable Immunoglobulin A-Coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation. . (weillcornell.org)

A post-hoc analysis of the phase 3 ADVANCE, MOTIVATE, and FORTIFY trials assessing risankizumab in participants with Crohn's disease (CD) confirmed the efficacy of induction and maintenance therapies with this agent. (sense-studios.com)
Little is known regarding the clinical and, in particular, pathological manifestations of patients with isolated colonic Crohn's disease. (harvard.edu)
Crohn's disease (CD) is a form of chronic inflammatory bowel disease (IBD). (mdpi.com)
It can be associated with various diseases or conditions, including as a complication of Crohn's disease , a type of inflammatory bowel disease causing inflammation of the digestive tract. (verywellhealth.com)
1 As a result, 187,000 hospitalizations per year, take place, specifically for Crohn's disease (CD) in the US. (maunakeatech.com)
Predicting relapse in Crohn's disease: a biopsychosocial model. (maunakeatech.com)
Prediction of clinical outcomes in Crohn's disease by using confocal laser endomicroscopy: results from a prospective multicenter study. (maunakeatech.com)
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. (snpedia.com)
on the Simple Endoscopic Score for Crohn's Disease (SES-CD), the mean lower gastrointestinal score fell from 13 to 4 in the treatment group but remained unchanged in the control group. (medscape.com)
The treatment group also showed a greater decrease than the control group in median Crohn's Disease Activity Index score (approximately 165 vs 50 points). (medscape.com)
To investigate the microbiological profile of intra-abdominal abscesses drained from patients with Crohn's disease (CD) compared to patients with complicated diverticulitis coli (cDC). (turkishjcrd.com)
Patients with Crohn's disease (CD) may develop intra-abdominal abscesses, which occur in 10% to 28% of patients. (turkishjcrd.com)
Intestinal involvement in endometriosis is quite common and can resemble several diseases such as Crohn's disease, appendicitis, tubo-ovarian abscess or malignant tumour. (njghonweb.org)
[3] , [4] These symptoms can mimic other pathologies such as Crohn's disease, appendicitis, tubo-ovarian abscesses, intestinal obstructions or malignancies, especially in patients without a previous history of endometriosis. (njghonweb.org)
Q: Another big illness associated with the gastrointestinal system is Crohn's disease. (gvhealthnews.com)
Low-Dose Naltrexone Therapy Improves Active Crohn's Disease," in the January issue of the American Journal of Gastroenterology (2007;102:1-9), officially presents LDN to the world of scientific medicine. (fasting.ws)
She concluded that "LDN therapy appears effective and safe in subjects with active Crohn's disease. (fasting.ws)

The mucosa associated colonic microflora of 57 patients with active inflammatory bowel disease and 46 controls was investigated using 16S rDNA based single strand conformation polymorphism (SSCP) fingerprint, cloning experiments, and real time polymerase chain reaction (PCR). (bmj.com)
Dietary Protein and Amino Acid Supplementation in Inflammatory Bowel Disease Course: What Impact on the Colonic Mucosa? (archives-ouvertes.fr)
also knows as antibiotic-associated colitis or Clostridium difficile colitis) is a descriptive term for colitides defined by the presence of pseudomembranes on the colonic or small intestinal mucosa. (medscape.com)
In Clostridium difficile associated diarrhoea (CDAD), histological changes in the colonic mucosa range from minimal inflammation to pseudomembranous colitis (PMC). (bmj.com)
Proctocolitis is associated with symptoms of proctitis plus diarrhea and/or abdominal cramps and inflammation of the colonic mucosa extending to 12 cm. (cdc.gov)

Diverticular disease is a common condition affecting large intestine in the western world, which, although remains asymptomatic in majority of people, can present with abdominal pain, acute diverticulitis, perforation, haemorrhage, intestinal obstruction and fistulation through neighbouring organs. (who.int)
Treatment of perforated diverticulitis depends on disease severity classified according to Hinchey's preoperative classification. (springer.com)
Nevertheless, the degree of peritonitis-and hence the severity of disease-in perforated diverticulitis can be represented best by the modified Hinchey's classification. (springer.com)
Colonic diverticulitis can cause abscess, fistula. (bvsalud.org)

IMSEAR at SEARO: Colonic diverticular disease: current perspectives. (who.int)
Complicated colonic diverticular disease (CDD) is associated with significant morbidity and mortality. (who.int)
The purpose of this article is to provide a comprehensive review of the epidemiology, pathophysiology, clinical presentations, and current management of diverticular disease of the colon and its complications. (who.int)
Diverticular disease has become more prevalent in Western countries [ 1 ]. (springer.com)
Colonic diverticular disease has been increasing in prevalence in Japan due to the rapidly aging population. (bvsalud.org)
Colonic diverticular bleeding can result in hemorrhagic shock requiring blood transfusion, and it carries a high risk of recurrence within 1 year. (bvsalud.org)
This is most frequently caused by angiodysplasia of the colon or diverticular disease. (surgery-home.com)
Diverticular disease essentially results from eating a diet that contains too little fiber. (healthcareformen.info)
Diverticular disease is most often found in men over the age of 40 and is rarely found in cultures with poor diets. (healthcareformen.info)

Although the length of the involved intestinal segment varies in this syndrome, most patients had total colonic aganglionosis with or without small bowel involvement. (jpedsurg.org)
We present in this study 2 siblings and one first-degree relative for a total of 3 male patients with Waardenburg syndrome and total colonic aganglionosis with or without small bowel involvement, together with their clinical characteristics and treatment methods. (jpedsurg.org)

As most of the colonic bacteria cannot be identified by culture techniques, genomic technology can be used for analysis of the composition of the microflora. (bmj.com)
The reduction in diversity in inflammatory bowel disease was due to loss of normal anaerobic bacteria such as Bacteroides species, Eubacterium species, and Lactobacillus species, as revealed by direct sequencing of variable bands and confirmed by real time PCR. (bmj.com)
Mucosal inflammation in inflammatory bowel disease is associated with loss of normal anaerobic bacteria. (bmj.com)
Certain antimicrobial classes that are broad-spectrum and have a propensity for killing colonic bacteria, especially cephalosporins, clindamycin, and most recently, fluoroquinolones, may pose a greater risk for the development of the disease. (cdc.gov)
We believe that psyllium acts by forming a gel, trapping inulin thereby excluding colonic bacteria and hence slowing and redirecting colonic fermentation to produce less gas but more short chain fatty acids (SCFAs). (ukri.org)
This substance cuts off the blood supply to the thin walls of the sac, which makes them more susceptible to attack by colonic bacteria. (healthcareformen.info)
It is believed that a link exists between gut microbiota and obesity and other metabolic diseases in hosts caused by the microbiota-derived toxic metabolites, extra energy derived from gut bacteria, and low-grade inflammation caused by endotoxemia. (juniperpublishers.com)

Dietary Vitamin E intake is associated with a reduced risk of developing digestive diseases and NAFLD. (greenmedinfo.com)
Digestive Diseases and Sciences, 2019. (maunakeatech.com)
The Asian Pacific Digestive Disease Week (APDW) is the premier annual scientific meeting in Asia Pacific region for digestive diseases. (apdwkl2021.org)

Gross pathologic findings ranged from no obvious lesions in mildly affected toads to thickened colonic walls with hyperemic serosal vasculature and hemorrhagic content in severely affected toads ( Figure 1 , panel A). Histologically appreciable lesions (invasive amebiasis) were commonly limited to the colon, although in severely affected toads, lesions extended through the small intestine and, rarely, into the stomach. (cdc.gov)
Colon is the distal organ of the GIT, hence difficulty arises in colonic drug delivery. (zenodo.org)
Widespread antibiotic use made PMC a common problem, and it became apparent that the disease primarily involved the colon and only rarely involved the small intestine. (medscape.com)
A recent compilation of these patients has suggested that Hirschsprung's disease may be predicted on the basis of nonfixation of the colon distal to the atresia. (jpedsurg.org)
The oral delivery method elevated the protein expression level of IL-22 in the colonic tissue of mice and accelerated the healing process, as demonstrated by the recovery of more body weight and colon length. (scienceboard.net)
The increased risks conferred by inflammatory bowel disease (IBD) to the development of colorectal cancer gave rise to the term "colitis-associated cancer" and the concept that inflammation promotes colon tumorigenesis. (aacrjournals.org)
Colon resections (colectomies) are performed to treat and prevent diseases and conditions that affect the colon, such as colon cancer (see the image below). (medscape.com)
Procesos patológicos en la región del COLON del INTESTINO GRUESO. (bvsalud.org)
STUDY 6: We will give the cellulose with inulin daily for 3 weeks to IBS patients before assessing gas and colonic volumes using MRI, relevant bowel symptoms (gas, pain, bloating) and stool fermentation pathways using our model colon. (ukri.org)
FODMAPs cause abdominal discomfort, bloating and flatulence by their rapid colonic fermentation which produces gas and distends the colon. (ukri.org)
Low FODMAP diets, although widely adopted, are expensive, inconvenient and may have negative effects on health by excluding high fibre foods (HFF) that protect against obesity-related diseases and colon cancer. (ukri.org)

Severe disease may show marked colonic dilatation, perforation, or pneumoperitoneum. (medscape.com)
Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives. (drugs.com)

Inflammatory bowel diseases (IBD), after disease onset, typically progress in two cyclically repeated phases, namely inflammatory flare and remission, with possible nutritional status impairment. (archives-ouvertes.fr)
Quantitative assessment of mucosal architecture using computer-based analysis of confocal laser endomicroscopy in inflammatory bowel diseases. (maunakeatech.com)
PMID 22569826 ] Abnormal Genetic and Epigenetic Changes in Signal Transducer and Activator of Transcription 4 in the Pathogenesis of Inflammatory Bowel Diseases. (snpedia.com)

Parkinson's disease (PD) is frequently associated with gastrointestinal symptoms, mostly represented by constipation and defecatory dysfunctions. (unipr.it)

The topic of this review is the key end products of colonic fermentation, the SCFA butyric, acetic, and propionic acids. (researchgate.net)
of colonic fermentation, the SCF A butyric, acetic, and propionic acids. (researchgate.net)
Psyllium is a dietary fibre which forms a gel when added to water but exactly how psyllium alters colonic fermentation is unknown. (ukri.org)
STUDY 2: This will use our colonic model to assess the effect of the different cellulose preparations on fermentation pathways in the laboratory. (ukri.org)
10) Mortensen PB et al.Colonic fermentation of ispaghula, wheat bran, glucose, and albumin to short-chain fatty acidsand ammonia evaluated in 50 subjects. (psyllium.fr)

See Benign or Malignant: Can You Identify These Colonic Lesions? (medscape.com)
Results: Colonic lesions were observed in 52% of patients with SCI and in 41.5% of control patients. (ewha.ac.kr)

Objectives: The hypothesis of the study was that if the gut microbiota is involved in the development of atherosclerotic cardiovascular and cerebrovascular diseases (CVDs), total colectomy may reduce the longterm risk of CVDs. (mssm.edu)
For these reasons, the gut microbiota and the brain influence each other via a bidirectional axis (the gut-brain axis), where the gut microbiota can exert control on brain functions in normal physiological conditions (from neurodevelopment till adulthood) and contribute to neurodevelopmental disorders (i.e., autism, schizophrenia, and Rett syndrome) and major brain diseases ( i.e . (frontiersin.org)
In a healthy symbi- posed of about as many microorgan- after the pioneering work of Gordon otic state, the colonic microbiota isms as there are cel s in the human and collaborators [1]. (who.int)
The colonic microbiome view is controversial, some people Metagenomics of the Human Intes- is the most diverse and also the best consider the gut microbiota to be tinal Tract (MetaHIT) consortium re- characterized microbial community. (who.int)
As a group of microbial species, intestinal microbiota plays a critical role in the health and disease of the host. (juniperpublishers.com)
The literature was reviewed in several ways show that gut microbiota has a tight association with host metabolism via the production of gut microbiota-derived metabolites, such as short-chain fatty acids (SCFAs) which can supply energy for colonic epithelial cells, trimethylamine-N-oxide (TMAO) which is associated with the formation of white adipose tissue and inosine-5-monophosphate (IMP) which has been found involved in the metabolism of lipids. (juniperpublishers.com)

Infection with toxigenic C difficile causes a spectrum of diseases ranging from the asymptomatic carrier state, particularly in neonates, to a fulminant relapsing and occasionally fatal colitis. (medscape.com)
Colonic biopsies were obtained from 12 control patients with diarrhoea, six patients with CDAD and minimal inflammation, and 10 patients with CDAD with pseudomembranous colitis (samples obtained from areas with and without inflammatory exudate). (bmj.com)
1- 3 The disease is mediated by two secreted toxins, 4 and its presentation ranges from asymptomatic carriage to life threatening and sometimes fatal pseudomembranous colitis (PMC). (bmj.com)
The development of colitis-associated cancer in patients suffering from inflammatory bowel disease (IBD) is one of the best characterized examples of an association between intestinal inflammation and carcinogenesis ( 4-7 ). (aacrjournals.org)
Certain medications, chemical injury, collagenous colitis, inflammatory bowel disease, ischemia, and other infectious pathogens can reportedly cause mucosal injury and subsequent pseudomembrane formation. (hindawi.com)
Pseudomembranous colitis is commonly associated with Clostridium difficile infection (CDI) but can be a consequence of other disease processes. (hindawi.com)

Gastric inflammation, duodenal inflammation, or both may be observed in as many as 30-40% of children with Crohn disease. (medscape.com)

The intestinal bacterial microflora plays an important role in the aetiology of inflammatory bowel disease (IBD). (bmj.com)
The perineum should be inspected in all patients who present with signs and symptoms of Crohn disease because abnormalities detectable in this region substantially increase the clinical suspicion of inflammatory bowel disease (IBD). (medscape.com)
Plain radiography may reveal colonic ileus, small bowel ileus, ascites, nodular thickening, or thumbprinting (wide transverse bands associated with haustral thickening). (medscape.com)
CT findings may include colonic wall thickening and nodularity, bowel wall stranding and edema, ascites, the accordion sign (ingested oral contrast becomes trapped between thickened haustral folds), and the double-halo sign (ie, submucosal edema indicated by 2 or 3 concentric rings in the large bowel on transverse imaging). (medscape.com)
Hirschsprung's disease (HSCR) is characterized by the absence of intramural ganglion cells in the distal gut, resulting in bowel obstruction shortly after birth. (jpedsurg.org)
The use of laxatives is contraindicated in patients with inflammatory bowel disease. (drugs.com)
Patients with colonic inflammatory bowel disease (IBD) have a high risk of colorectal cancer (CRC). (aegastro.es)
Cellvizio® is the real-time in vivo cellular imaging platform that allows you to observe, understand, and predict relapse and remission cycles while managing Inflammatory Bowel Disease. (maunakeatech.com)
How to predict clinical relapse in inflammatory bowel disease patients. (maunakeatech.com)
Personalized Inflammatory Bowel Disease Care Reduced Hospitalizations. (maunakeatech.com)
Colonic lesion characterization in inflammatory bowel disease: A systematic review and metaanalysis. (maunakeatech.com)
Our dedicated physicians and clinical team treat digestive issues like esophageal disorders, stomach and small bowel conditions, colonic disorders, and other diseases that involve the digestive system including the liver, pancreas, bile duct, and gallbladder. (southernregional.org)
A small bowel enteroscopy is a type of endoscopy procedure that may be used in the diagnosis and management of several different types of digestive condition evaluates gastrointestinal bleeding, small bowel tumors, polyps, or other small bowel diseases. (southernregional.org)
If medical therapy for active Crohn disease fails, surgical resection of the inflamed bowel, with restoration of continuity, is indicated. (medscape.com)
2018. Testing and Treating Small Intestinal Bacterial Overgrowth Reduces Symptoms in Patients with Inflammatory Bowel Disease. . (weillcornell.org)
Inflammatory bowel disease, which is a risk factor for cancer, was the most common findings in the SCI group, although there was no significant difference from the control group. (ewha.ac.kr)
[1] Other causes include diarrhea , sexually transmitted infections , inflammatory bowel disease , childbirth , HIV/AIDS , anal cancer , and anal sex . (mdwiki.org)
When fissures are found laterally, tuberculosis, occult abscesses, leukemic infiltrates, carcinoma, acquired immunodeficiency syndrome (AIDS) or inflammatory bowel disease should be considered as causes. (mdwiki.org)
Hirschsprung disease is the absence of intrinsic ganglion cells in the bowel wall (specifically the submucosal and myenteric plexuses). (choc.org)

Systemic diseases such as cystic fibrosis , diabetes mellitus , hyper or hypothyroidism , Down syndrome . (wikidoc.org)
Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus. (snpedia.com)
It's a systemic autoimmune disease, but why does it seem to cause such problems in the intestines? (gvhealthnews.com)

This study examined the impact of central dopaminergic denervation, induced by injection of 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle, on distal colonic excitatory cholinergic neuromotor activity in rats. (unipr.it)

Primary and secondary outcome measures: The primary outcome was the first occurring CVD event in any of the seven diagnostic domains (hypertensive disorders, acute ischaemic heart diseases, chronic ischaemic heart disease, cardiac arrhythmias, heart failure, cerebrovascular diseases and other arterial diseases) and the secondary outcomes were the first occurring event within each of these domains. (mssm.edu)
The CDC recommends antiparasitic treatment for all cases of acute (ie, congenital) or reactivated Chagas disease and for chronic T cruzi in children up to age 18 years. (medscape.com)
Acute kidney injury (AKI) is a life-threatening disease with high mortality characterized by an abrupt decrease of the kidney glomerular filtration rate, extra-kidney consequences (cardiovascular diseases, lung injury, neurological impairment) and high risk of secondary chronic kidney disease (CKD). (hrb.ie)

Centers for Disease Control and Prevention. (cdc.gov)
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
09/24/1993 SUGGESTED CITATION Centers for Disease Control and Prevention. (cdc.gov)

The coexistence of colonic atresia and Hirschsprung's disease presents a diagnostic and therapeutic challenge. (jpedsurg.org)
Colonic atresia is quickly recognized, and the majority of patients are diverted shortly after birth. (jpedsurg.org)

Review post-surgical and functional complications in children with anorectal malformations and Hirschsprung disease. (choc.org)

The clinical presentation is primarily determined by the location and extent of the patient's disease. (medscape.com)
Some evidence, either from epidemiological, clinical, and experimental studies indicate that the quantity and the quality of dietary protein consumption and amino acid supplementation may differently influence the IBD course according to the disease phases. (archives-ouvertes.fr)
By the other hand, uncompleted disease remission after CS use, that is, clinical but not endoscopic remission, has been associated with a higher risk of hospitalizations and need for immunomodulator or colectomy in UC. (clinicaltrials.gov)
The efficacy of selected probiotics for prophylaxis and treatment of chronic inflammatory, infectious, and allergic diseases has been confirmed by randomized controlled clinical trials. (aerzteblatt.de)
This and the fact that the number and size of clinical trials are limited do not warrant general recommendation of the mentioned probiotics for treatment of selected diseases. (aerzteblatt.de)
Infection can be subclinical or cause clinical disease. (merckvetmanual.com)
It also allows identification of residual colonic inflammation not detectable macroscopically in patients with IBD which in turn can help in determining the need for additional anti-inflammatory therapy and allows prediction of clinical outcomes. (maunakeatech.com)
The development of biologic anti-tumor necrosis factor (anti-TNF) agents (eg, infliximab, adalimumab, certolizumab pegol, and natalizumab) has significantly advanced the treatment of Crohn disease and improved the induction and maintenance of clinical remission in patients with moderate to severe disease, especially in those who are corticosteroid dependent. (medscape.com)

Become familiar with anorectal malformations and Hirschsprung disease. (choc.org)
Know the workup in children with anorectal malformations and Hirschsprung disease who have complications after their initial surgeries. (choc.org)

microRNAs are small non-protein-coding RNA molecules that regulate gene expression, and have a potential epigenetic role in disease progression and survival of colorectal cancer. (biomedcentral.com)
During his portion of the talk, Dr. Chogle discussed the importance of the team of specialists who work with children with colorectal disorders, including Hirschsprung disease and severe constipation. (choc.org)

Most likely because of increased toxin production as well as other virulence factors, this epidemic strain has caused more severe and refractory disease leading to complications, including intensive care unit admission, colectomies, and death. (cdc.gov)
Beginning in 2000, widespread regional outbreaks of C . difficile strains involving more severe and refractory disease have occurred, with greater numbers of complications, colectomies, and deaths than previously described [ 3 - 6 ]. (cdc.gov)

The diagnosis of coincident Hirschsprung's disease usually is made after anastomotic failure after restoration of intestinal continuity. (jpedsurg.org)
Evaluation of adult chronic Chagas' heart disease diagnosis by molecular and serological methods. (medscape.com)

A) Toad with severe colonic amebiasis. (cdc.gov)
B) Photomicrograph of colonic amebiasis. (cdc.gov)
Although other species of amebae (eg, Naegleria fowleria , Acanthamoeba spp, and Balamuthia mandrillaris ) cause disease in veterinary species as well as humans, the term amebiasis usually refers specifically to infections with E histolytica . (merckvetmanual.com)

Colonic slow transit (or hypo motility). (nutritionvista.com)

Constipation must be differentiated from infantile dischezia, Hirschsprung's disease , and cystic fibrosis . (wikidoc.org)
Symptoms of Hirschsprung disease include intractable constipation, abnormal distention and bilious vomiting, among others. (choc.org)

Organic - the most common causes being celiac disease , hypothyroidism , and cow's milk protein allergy. (wikidoc.org)
Other causes such as cow's milk allergy or celiac disease . (wikidoc.org)
Non-responsive celiac disease in children on a gluten free diet. (harvard.edu)
Antibody tests for celiac disease were negative. (hindawi.com)

It's an autoimmune condition, but sometimes in medicine when a disease doesn't have an etiology, we name it after a patient or physician. (gvhealthnews.com)

A selective reduction in mucosal IgA producing cells and macrophages is associated with colonic disease in C difficile infected patients. (bmj.com)

Severe reduction in colonic IgA producing cells may predispose to recurrence of CDAD. (bmj.com)

Use the internet to explore the alternatives to prescription drugs when it comes to health, prevention and living a disease-free life. (safemenopausesolutions.com)

The mice also had reduced histological index, colonic myeloperoxidase activity, fecal lipocalin concentration, and mRNA expression levels of proinflammatory cytokines. (scienceboard.net)

Patients with upper gastrointestinal (GI) Crohn disease condition may experience nausea, vomiting, and abdominal pain as dominating presenting symptoms. (medscape.com)
Children with Crohn disease of the small intestine usually present with evidence of malabsorption, including diarrhea, abdominal pain, growth deceleration, weight loss, and anorexia. (medscape.com)

Using mice models, researchers from Japan and China have shown that dendritic cell immunoreceptor (DCIR) protein deficiency is resistant to colonic tumors. (scienceboard.net)

Cellular damage produced by conditions generating oxidative stress have far-reaching implications in human disease that encompass, but are not restricted to aging, cardiovascular disease, type 2 diabetes, airway inflammation/asthma, cancer, and metabolic syndrome including visceral obesity, insulin resistance, fatty liver disease, and dyslipidemia. (luciolepharma.com)

A higher pH in colonic lumen may also be a result of decreased gastric acid production after surgery. (juniperpublishers.com)

We present the case of a middle-aged woman with vascular disease who was incorrectly diagnosed with refractory C. difficile infection due to the presence of pseudomembranes. (hindawi.com)

Cytotoxic T Lymphocyte Antigen 4 Haploinsufficiency Presenting As Refractory Celiac-Like Disease: Case Report. (harvard.edu)

To investigate mucosal immune system cells in colonic biopsies of patients with CDAD. (bmj.com)

The Waardenburg-Shah syndrome is an autosomal recessive disease with varied penetration where Hirschsprung's disease and the Waardenburg syndrome are seen together. (jpedsurg.org)
It is extremely rare that Hirschsprung's disease (HSCR) merges with a disorder showing abnormality of the L1CAM genes such as acrocallosal syndrome (ACS) or X-linked hydrocephalus (XLH). (jpedsurg.org)
Care must be taken to exclude urgent causes such as Hirschsprung's disease , cystic fibrosis , lead poisoning , infantile botulism , obstruction, and malformations of the spine. (wikidoc.org)
Hirschsprung's disease can present with difficulties in passing stool in the neonatal period because of colonic agangliosis. (wikidoc.org)
However, Hirschsprung's disease would also present with bilious vomiting , refusal to feed, and a fever caused by severe enterocolitis . (wikidoc.org)

Although widely promoted as a health food, hundreds of studies link modern processed soy to malnutrition, digestive problems, thyroid dysfunction, cognitive decline, reproductive disorders, immune system breakdown, and even heart disease and cancer. (nourishingourchildren.org)
FDA-approved naltrexone, in a low dose, can boost the immune system - helping those with HIV/AIDS, cancer, autoimmune diseases, and central nervous system disorders. (fasting.ws)

[ 84 ] Anti-TNF agents are effective for induction and maintenance of remission in patients with Crohn disease and active inflammation. (medscape.com)
Antibiotics can decrease anal fistula discharge and may induce remission in Crohn disease. (medscape.com)
Autoimmune disease affects 10% of adults, most of whom are women, and two of the top five medications with the highest cost globally are used to maintain these recurring conditions in remission. (hrb.ie)

Modulation of gut flora and intestinal barrier functions by pro- and prebiotics is a research field that opens new insights into the pathophysiology of immune-mediated, food-related, and infectious diseases of the intestine and outside the intestine. (aerzteblatt.de)
Polyphenols exert preventive activity against infectious and degenerative diseases including oral diseases. (bvsalud.org)
Polyphenols (PPs) exert preventive activity against infectious and degenerative diseases and may also help prevent oral diseases via various mechanisms 58 . (bvsalud.org)

Patients with suspected Crohn disease should initially be evaluated by their primary care team. (medscape.com)
The onset of growth failure is usually insidious, and any child or adolescent with persistent alterations in growth should undergo appropriate diagnostic evaluation for Crohn disease. (medscape.com)
Gupta et al identified risk factors for impaired statural growth in children with Crohn disease, which differ by sex. (medscape.com)
Treatment of Crohn disease is made on the basis of the disease site, pattern, activity, and severity. (medscape.com)
Treatment of Crohn disease has changed over the past few years, reflecting new therapies that can target specific locations in the gastrointestinal (GI) tract and specific cytokines. (medscape.com)
The first randomized controlled trial of stem cell transplantation in treatment-resistant Crohn disease was performed in 2013, in 45 patients with moderately to severely active disease. (medscape.com)
Many patients with an exacerbation of Crohn disease can be treated on an outpatient basis. (medscape.com)
Treatment of metastatic cutaneous Crohn disease with certolizumab. (weillcornell.org)

You can juice to treat a variety health conditions including arthritis, heart disease, cancer, high cholesterol, menopause, ulcers, impotence and prostate problems and even fluid retention. (movementforhappiness.org)
According to a hypothesis, polyphenol (PP) activity against several forms of cancer, proliferative diseases, inflammation and neurodegeneration is mainly exerted through the inhibiting and modulating activities against a wide range of receptors, enzymes and transcription molecules 88 . (bvsalud.org)
Research has shown that low-fiber diets can cause stroke, heart disease and certain kinds of cancer. (thinktwicepakistan.com)

A fistula can occur because of a disease or condition. (verywellhealth.com)

that infiltrates the colonic lining, causing it to slough. (cdc.gov)

SARS-CoV-2 coinfection with additional respiratory virus does not predict severe disease: a retrospective cohort study. (cornell.edu)

Painful defecation, bright red rectal bleeding, and perirectal pain, erythema, or discharge may signal perianal disease and may occur without symptomatic involvement in any other area of the GI tract. (medscape.com)
The analysis further showed that risankizumab therapy is more efficacious in participants with CD who had colonic involvement than in those who had ileal involvement. (sense-studios.com)

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. (cornell.edu)

Findings on physical examination depend on the duration and extent of the disease and on the extraintestinal manifestations. (medscape.com)
These findings indicate that central nigrostriatal dopaminergic denervation is associated with an impaired excitatory neurotransmission characterized by a loss of myenteric neuronal ChAT positivity and decrease in acetylcholine release, resulting in a dysregulated smooth muscle motor activity, which likely contributes to the concomitant decrease in colonic transit rate. (unipr.it)

1980. Inhibition by bran of the colonic cocarcinogenicity of bile salts in rats given dimethylhydrazine. (cdc.gov)

Transmural disease presents with colonic wall thickening and features of intestinal obstruction. (hindawi.com)

And we know that disease location may affect treatment outcomes of biologic therapies in CD," explained Dr Peter Bossuyt (Imelda General Hospital, Belgium) [1,2]. (sense-studios.com)
Body based methods are founded on the body's manipulation - they include chiropractic manipulation, colonic and massage therapies. (safemenopausesolutions.com)

Obesity is a risk factor for both susceptibility to infections including postoperative infections and other nosocomial infections and the occurrence of a more severe disease course. (hrb.ie)

Anatomy3

Diseases6

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Reconstruction for chronic dysfunction of ileoanal pouches. (1/670)

The pathophysiology of disseminated Mycobacterium avium complex disease in AIDS. (2/670)

Psoas abscesses complicating colonic disease: imaging and therapy. (3/670)

The colonic mesenteric margin is most susceptible to injury in an experimental model of colonic ulceration. (4/670)

Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor. (5/670)

Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon. (6/670)

Laparoscopic-assisted colectomy: a comparison of dissection techniques. (7/670)

Laparoscopic colon surgery for benign disease: a comparison to open surgery. (8/670)

Colonic Diseases

Crohn Disease

Colon

Enema

Colitis, Ulcerative

Rectum

Colonoscopy

Intestinal Mucosa

Colonic Diseases, Functional

Colonic Neoplasms

Colonic Polyps

Reconstruction for chronic dysfunction of ileoanal pouches. (1/670)

The pathophysiology of disseminated Mycobacterium avium complex disease in AIDS. (2/670)

Psoas abscesses complicating colonic disease: imaging and therapy. (3/670)

The colonic mesenteric margin is most susceptible to injury in an experimental model of colonic ulceration. (4/670)

Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor. (5/670)

Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon. (6/670)

Laparoscopic-assisted colectomy: a comparison of dissection techniques. (7/670)

Laparoscopic colon surgery for benign disease: a comparison to open surgery. (8/670)

Colonic Diseases

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Colectomy

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The Colonic

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Hirschsprung's disease

Diverticular disease

Anorectal disorder

Hinchey Classification

Diverticulitis

Volvulus

Colorectal Disease Treatments | Smart Living | St. Joseph's/Candler