Tumors or cancer of the COLON.
The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.
A segment of the COLON between the RECTUM and the descending colon.
The segment of LARGE INTESTINE between the CECUM and the TRANSVERSE COLON. It passes cephalad from the cecum to the caudal surface of the right lobe of the LIVER where it bends sharply to the left, forming the right colic flexure.
The segment of LARGE INTESTINE between ASCENDING COLON and DESCENDING COLON. It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon.
Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS.
A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.
A pouch or sac opening from the COLON.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
A malignant epithelial tumor with a glandular organization.
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
A cell line derived from cultured tumor cells.
Hydrazines substituted with two methyl groups in any position.
Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)
Endoscopic examination, therapy or surgery of the luminal surface of the colon.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
A benign epithelial tumor with a glandular organization.
Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.
Tumors or cancer of the SIGMOID COLON.
Tumors or cancer of the RECTUM.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
The motor activity of the GASTROINTESTINAL TRACT.
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.
Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.
Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.
A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
The surgical construction of an opening between the colon and the surface of the body.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
Tumors or cancer of the CECUM.
Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.
Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Experimental transplantation of neoplasms in laboratory animals for research purposes.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.
A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.
High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.
The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
A reagent that is used to neutralize peptide terminal amino groups.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Agents that are used to stimulate evacuation of the bowels.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Transplantation between animals of different species.
Tumors or cancer of the INTESTINES.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.
Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Regular course of eating and drinking adopted by a person or animal.
A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Elements of limited time intervals, contributing to particular results or situations.
The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Hydrazines substituted by one or more methyl groups in any position.
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)
A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.
Opening or penetration through the wall of the INTESTINES.
A plastic operation on the esophagus. (Dorland, 28th ed)
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).
Dilatation of the COLON, often to alarming dimensions. There are various types of megacolon including congenital megacolon in HIRSCHSPRUNG DISEASE, idiopathic megacolon in CONSTIPATION, and TOXIC MEGACOLON.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)
DNA present in neoplastic tissue.
In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Tumors or cancer of the LIVER.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Uptake of substances through the lining of the INTESTINES.
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.
Endoscopic examination, therapy or surgery of the sigmoid flexure.
The contents included in all or any segment of the GASTROINTESTINAL TRACT.
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Short-chain fatty acids of up to six carbon atoms in length. They are the major end products of microbial fermentation in the ruminant digestive tract and have also been implicated in the causation of neurological diseases in humans.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.
Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
Antibodies produced by a single clone of cells.
The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Established cell cultures that have the potential to propagate indefinitely.
An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Antimetabolites that are useful in cancer chemotherapy.
Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
The normal process of elimination of fecal material from the RECTUM.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
Specially designed endoscopes for visualizing the interior surface of the colon.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
RNA present in neoplastic tissue.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Organic compounds which contain platinum as an integral part of the molecule.
An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
The action of a drug in promoting or enhancing the effectiveness of another drug.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.
Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)
A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).
A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)
A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).
A subcategory of mucins that contain SIALIC ACID.
Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.
Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.
A rod-shaped, gram-positive, non-acid-fast, non-spore-forming, non-motile bacterium that is a genus of the family Bifidobacteriaceae, order Bifidobacteriales, class ACTINOBACTERIA. It inhabits the intestines and feces of humans as well as the human vagina.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
The combination of two or more different factors in the production of cancer.
Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.
Tumors or cancer of the LUNG.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

A smooth muscle tone-dependent stretch-activated migrating motor pattern in isolated guinea-pig distal colon. (1/35)

We have investigated the tone dependence of the intrinsic nervous activity generated by localized wall distension in isolated segments of guinea-pig distal colon using mechanical recordings and video imaging of wall movements. A segment of colon was threaded through two partitions, which divided the colon for pharmacological purposes into oral, stimulation and anal regions. An intraluminal balloon was located in the stimulation region between the two partitions (12 mm apart). Maintained colonic distension by an intraluminal balloon or an artificial faecal pellet held at a fixed location generated rhythmic (frequency 0.3 contractions min(-1); duration approximately 60 s) peristaltic waves of contraction. Video imaging of colonic wall movements or the selective application of pharmacological agents suggested that peristaltic waves originated just oral (< or = 4 mm) to the pellet and propagated both orally (approximately 11 mm s(-1)) and anally (approximately 1 mm s(-1)). Also, during a peristaltic wave the colon appears to passively shorten in front of a pellet, as a result of an active contraction of the longitudinal muscle oral to the pellet. Faecal pellet movement only occurred when a rhythmic peristaltic wave was generated. Rhythmic peristaltic waves were abolished in all regions by the smooth muscle relaxants isoproterenol (1 microM), nicardipine (1 microM) or papavarine (10 microM), and by the neural antagonists tetrodotoxin (TTX; 0.6 microM), hexamethonium (100 microM) or atropine (1 microM), when added selectively to the stimulation region. Nicardipine, atropine, TTX, or hexamethonium (100 microM) also blocked the evoked peristaltic waves when selectively added to the oral region. Nomega-nitro-L-arginine (L-NA; 100 microM) added to the anal region reduced the anal relaxation but increased the anal contraction, leading to an increase in the apparent conduction velocity of each peristaltic wave. In conclusion, maintained distension by a fixed artificial pellet generates propulsive, rhythmic peristaltic waves, whose enteric neural activity is critically dependent upon smooth muscle tone. These peristaltic waves usually originate just oral to the pellet, and their apparent conduction velocity is generated by activation of descending inhibitory nerve pathways.  (+info)

Distinguishing right from left colon by the pattern of gene expression. (2/35)

Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis. These differences may reflect distinct biological characteristics of proximal and distal colonic mucosa, acquired in embryonic or postnatal development, that determine a differential response to uniformly distributed environmental factors. Alternatively, the differences in the epidemiology of proximal and distal CRCs could result from the presence of different procarcinogenic factors in the ascending versus descending colon, acting on cells with either similar or distinct biological characteristics. We applied cDNA microarray technology to explore the possibility that mucosal epithelium from adult proximal and distal colon can be distinguished by their pattern of gene expression. In addition, gene expression was studied in fetal (17-24 weeks gestation) proximal and distal colon. More than 1000 genes were expressed differentially in adult ascending versus descending colon, with 165 genes showing >2-fold and 49 genes showing >3-fold differences in expression. With almost complete concordance, biopsies of adult colonic epithelium can be correctly classified as proximal or distal by gene expression profile. Only 87 genes were expressed differently in ascending and descending fetal colon, indicating that, although anatomically relevant differences are already established in embryonic colon, additional changes in gene expression occur in postnatal development.  (+info)

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/35)

1. Mechanisms involved in Ca(2+) sensitization of contractile elements induced by the activation of muscarinic receptors in membrane-permeabilized preparations of the rat proximal and distal colon were studied. 2. In alpha-toxin-permeabilized preparations from the rat proximal and distal colon, Ca(2+) induced a rapid phasic and subsequent tonic component. After Ca(2+)-induced contraction reached a plateau, guanosine 5'-triphosphate (GTP) and carbachol (CCh) in the presence of GTP further contracted preparations of both the proximal and distal colon (Ca(2+) sensitization). Y-27632, a rho-kinase inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization more significantly in the proximal colon than in the distal colon. 3. Y-27632 at 10 microm had no effect on Ca(2+)-induced contraction or slightly inhibited phorbol-12,13-dibutyrate-induced Ca(2+) sensitization in either proximal or distal colon. Chelerythrine, a protein kinase C inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization in the distal colon, but not in the proximal colon. The component of Ca(2+) sensitization that persisted after the chelerythrine treatment was completely inhibited by Y-27632. 4. In beta-escin-permeabilized preparations of the proximal colon, C3 exoenzyme completely inhibited GTP plus CCh-induced Ca(2+) sensitization, but PKC(19-31) did not. In the distal colon, C3 exoenzyme abolished GTP-induced Ca(2+) sensitization. It inhibited CCh-induced sensitization by 50 % and the remaining component was inhibited by PKC(19-31). 5. These results suggest that both protein kinase C and rho pathways in parallel mediate the Ca(2+) sensitization coupled to activation of muscarinic receptors in the rat distal colon, whereas the rho pathway alone mediates this action in the proximal colon.  (+info)

Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/35)

BACKGROUND: Because of their suggested link with microsatellite instability high colorectal cancers, right sided hyperplastic polyps (HPs) may differ from their distally located counterparts. This is highlighted by the recognition of a variant HP, termed sessile serrated adenoma (SSA), which predominates in the proximal colon. HPs displaying the morphological features now associated with SSAs have been shown to have altered expression of "cancer associated" markers, but no studies have investigated whether this is dependent on anatomical location of the polyps. AIMS: To evaluate morphological and functional features in right versus left sided HPs from patients without colorectal cancer with the aim of identifying distinguishing characteristics. METHODS: HPs originating in the proximal and distal colorectum were histochemically and immunohistochemically stained to evaluate a panel of markers related to proliferation and differentiation. In addition, a series of morphological features was evaluated for each polyp. RESULTS: Crypt serration, crypt dilatation, and horizontal crypt growth were more common among HPs from the right side, whereas histochemical factors including mucin changes, global methylation status, and expression of carcinoembryonic antigen were not significantly different. An age disparity was also seen between patients with right versus left sided lesions, with patients with right sided lesions being an average of more than 10 years younger than those with left sided lesions. CONCLUSIONS: These findings suggest that right and left sided HPs differ mainly in terms of growth regulation rather than cellular differentiation, implying that these lesions belong to a continuous spectrum of serrated polyps that differ quantitatively rather than qualitatively.  (+info)

Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy. (5/35)

AIM: To review the risk of proximal colon cancer in patients undergoing colonoscopy. METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination). Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma). The sites of neoplasms were defined as rectosigmoid (rectum and sigmoid colon) and proximal colon (from cecum to descending colon). RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings. Among the 157 patients with proximal colon cancer, 74% had no neoplasm in the rectosigmoid colon. Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer. CONCLUSION: Sigmoidoscopy is inadequate for colorectal cancer screening, especially in older populations.  (+info)

Withdrawing method of the stiffening tube incidentally inserted into the descending colon. (6/35)

We experienced a very rare complication of colonoscopy, a migration of stiffening tube into the colorectum. We herein introduce a withdrawing method of migrating stiffening tube incidentally inserted into the colorectum. A 65-year-old Japanese woman underwent colonoscopy because of abdominal discomfort. We used stiffening tube to insert the scope to the proximal colon because of her redundant sigmoid colon. When withdrawing the scope, we realized that the tube was fully inside the colorectum. We could not remove the tube instantly, and it reached the splenic flexure, finally. We reinserted the scope through the migrating tube, straightened the scope, and withdrew it holding a slight angle of the scope over the proximal end of the tube. Then, we could safely remove the tube along with the scope through the anus.  (+info)

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (7/35)

BACKGROUND: Despite the fact that the alimentary tract is part of the body's first line of defense against orally ingested xenobiotica, little is known about the distribution and expression of cytochrome P450 (CYP) enzymes in human colon. Therefore, expression and protein levels of four representative CYPs (CYP2C(8), CYP2E1, CYP3A4, and CYP3A5) were determined in human colon mucosa biopsies obtained from ascending, descending and sigmoid colon. METHODS: Expression of CYP2C, CYP2E1, CYP3A4, and CYP3A5 mRNA in colon mucosa was determined by RT-PCR. Protein concentration of CYPs was determined using Western blot methods. RESULTS: Extensive interindividual variability was found for the expression of most of the genes. However, expression of CYP2C mRNA levels were significantly higher in the ascending colon than in the sigmoid colon. In contrast, mRNA levels of CYP2E1 and CYP3A5 were significantly lower in the ascending colon in comparison to the descending and sigmoid colon. In sigmoid colon protein levels of CYP2C8 were significantly higher by ~73% than in the descending colon. In contrast, protein concentration of CYP2E1 was significantly lower by ~81% in the sigmoid colon in comparison to the descending colon. CONCLUSION: The current data suggest that the expression of CYP2C, CYP2E1, and CYP3A5 varies in different parts of the colon.  (+info)

Comparative study of descendent colon rupture resistance considering traction force of rupture and total energy of rupture in rats. (8/35)

PURPOSE: To compare total energy of rupture and traction force of rupture tests within a rupture resistance study of descendent colon of rats. METHODS: Twelve descendent colon segments of rats were considered to perform the study. For each one of the specimens, total energy of rupture and traction force of rupture necessary to promote colic wall burst were evaluated through the biomechanical total energy of rupture test using the Biomechanical Data Acquisition and Analysis System, version 2.0. Average, standard deviation, standard error of average and coefficient of variation were considered for analysis of results. RESULTS: Traction force of rupture average, standard deviation, standard error of average and coefficient of variation were 380.05 gf, 98.74, 28.5 e 25.98%, respectively while total energy of rupture presented average of 244.85 gf, standard deviation of 57.76, standard error of average of 16.67 and coefficient of variation of 23.59. CONCLUSION: Although, total energy of rupture considered a larger number of attributes to its calculation related to non-linear viscoelastic materials, such as colic wall, it presented a smaller coefficient of variation when compared to traction force of rupture, thus demonstrating to constitute a possible parameter to analyze intestinal resistance of rats.  (+info)

A patient with abdominal discomfort, weight loss, and general weakness was discovered by way of ultrasound and computed tomography to have a tumor in the lower pole of the left kidney. At a second computed tomography examination, the mass had shrunken and air-fluid levels and contrast medium from previous examinations were evident, confirming a renocolic fistula. The patient underwent en bloc left radical nephrectomy with resection of the descending colon. Renal cell carcinoma was confirmed histologically. The patient has been free of disease for 4 years. Such fistulas are usually related to renal calculi or tuberculosis but, of late, more have been the result of iatrogenic trauma sustained during percutaneous renal procedures and lithotripsy. Use of computed tomography and other imaging methods should enable early detection of most renocolic fistulas, which usually are a late manifestation of advanced renal disease. ...
An EVAR often requires multiple wires and catheters be transferred into the vessel via an introducer sheath, which can lead to blood loss through the sheath valve. The sheaths exclusive DrySeal valve is designed to minimise blood loss, enabling the introduction of multiple devices with haemostasis control.. Nearly a third of patients being considered for EVAR have an aneurysm that extends to the iliac artery. The Excluder device is a trusted solution in such cases, but previously no introducer sheaths designed for use with this device existed, said Marcus Brooks, consultant vascular surgeon, North Bristol NHS Trust, UK. With the Gore DrySeal Flex introducer sheath, I now have a sheath specifically designed for use with the iliac branch endoprosthesis and flexible enough for easy access to the iliac branch vessels.. The new sheath leverages technology from Gores DrySeal Sheath, which features a hydrophilic coating for improved access into vessels. In addition, the DrySeal sheath offers an ...
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The present embodiments provide an introducer sheath having a braided member and methods of manufacture. The introducer sheath comprises an inner tube, a braided member disposed over at least a portion of the inner tube, and an outer tube disposed over the inner tube and the braided member. In one embodiment, the braided member comprises a plurality of intersecting first and second wire segments at least partially covered with a coating. At least a portion of the first and second wire segments are bonded together at one or more intersections, for example, by melting the coating, to reduce movement of at least one of the first and second wire segments with respect to one another. Optionally, a coiled member having a plurality of turns may be disposed over a portion of the braided member and the inner tube.
An introducer sheath (10) is provided for percutaneous insertion of catheters into a blood vessel. The introduction of the sheath (10) through a wall of blood vessel causes an opening to be formed thr
Designed for easy insertion and for patient comfort, Input® Introducer Sheaths are offered in two brands - Input TS and Input PS.
INTRODUCTION: There are several alternatives for one-stage emergency treatment of obstructive left-sided colonic cancer (OLCC): subtotal colectomy, intraoperative colon lavage (IOCL) with primary anastomosis, and the placement of a stent as a temporary measure prior to scheduled surgery. At present, it is not clear whether emergency perioperative lavage or the placement of a stent is the better technique. The hypothesis is that IOCL and primary anastomosis is equal safe or even safer than placement of a stent as a temporary measure prior to scheduled surgery, less length of stay and less cost.. OBJECTIVE: To establish which of these two techniques is more efficient in OLCC from the point of view of morbimortality, economic cost, and long-term survival.. MATERIAL AND METHODS:. Prospective, controlled, randomized study of patients diagnosed with OLCC. Patients were divided into two groups: group 1: stent and deferred surgery; group 2: emergency IOCL. A simple randomization system was used. The ...
A method of indicating divergent product benefits by formulating a hand dishwashing liquid having a cleaning agent and a hand care agent; choosing a sensory element profile comprising one or more soft colors and a pearlescent appearance; and incorporating the sensory element profile into the hand dishwashing liquid, such that the sensory element profile indicates the efficacy of the cleaning agent and the efficacy of the hand care agent.
A prospective, randomized, controlled multi-center clinical trial designed to evaluate the safety and effectiveness of the study device in sealing multiple femoral venous access sites and providing reduced times to ambulation compared with manual compression at the completion of catheter-based procedures performed through 6 - 12 Fr introducer sheaths.. Only patients with multiple access sites will be enrolled in order to support the desired indication. Randomization will be stratified to account for patients with varying numbers of access sites in a 1:1 treatment device to control arm ratio to ensure treatment and control arms have the same proportion of access sites/patient, i.e. 3 access sites/patient vs. 4 access sites/patient. ...
Introducers are intended to be inserted percutaneously into a vessel to facilitate the entire interventional procedure. A platinum/iridium band incorporate
box]. Cut the TP rolls into halves and the kitchen rolls into thirds to make smaller rolls. Decorate them with stickers. You could ask your older child to decorate the rolls for you. Sticking and peeling will be a fun fine motor activity for your older child. Your baby might have fun peeling off though and that again was ok since Id see that as a fine motor activity as well. My preschooler was very excited to decorate the paper rolls with stickers and painters. Using tape for holding the cards turned out great since it gave the paper rolls an additional sensory element while playing. You can use any safe sensory element to add to the roll to make playing for baby more exciting.. ...
A method for hemostasis of an artery having a puncture after arterial catheterization, the catheterization using an introducer sheath, the method including the steps of inserting a catheter with a first balloon into the introducer sheath, positioning the first balloon against an outside surface of a wall of the artery at the puncture, inflating the first balloon against the outside surface of the artery at the puncture, and maintaining the first balloon against the puncture so that the first balloon substantially seals blood flow from the puncture so as to achieve hemostasis.
Kayleigh Risser, RA, Reza Gamagami, MD. Silver Cross Hospital. Background: With increasing adoption of laparoscopy for the treatment of colorectal neoplasms, accurate preoperative localization is crucial as most tumors are invisible intraoperatively. There is usually no tactile feedback to assess the presence of a neoplasm. Furthermore, for rectal and rectosigmoid neoplasms, an accurate distance from anal verge will impact whether a patient will receive a colorectal anastomosis versus a coloanal anastomosis with a diversion. The aim of this study was to determine if there was a significant difference between the location of the left-sided colonic neoplasm described by the gastroenterologist as compared to the one performed by the operating surgeon prior to surgery.. Patients and Methods: A single surgeon retrospective analysis of patients referred for left-sided colonic neoplasm (n=85) for laparoscopic surgery from May 2012 to August 2018 was evaluated. Assessed data included: rectal vs. ...
To define the characteristics of colorectal cancer with regard to site distribution, age, and sex, due to the significantly increased incidence of colorectal cancer in Japan, we investigated 1,205 Japanese patients with colorectal cancer between 1975 and 1994. When we compared site distribution for age and sex in the entire 20-year period,...
A holding device and method of use with a peelable or otherwise splittable introducer sheath or catheter through which a cardiac pacing lead or other elongated flexible instrument extends into the body of a living being. The introducer is arranged to be grasped by a user to pull the introducer in the proximal direction so that can be withdrawn out of the beings body. The holding device comprises a first or
6 Mil Blue Vinyl Tape is a highly durable UV-treated poly-vinyl tape that stays in place for up to 6 months yet removes easily without leaving residue. This industrial vinyl tape protects surfaces providing good abrasion, impact and rupture resistance.
A vascular clip includes a peripheral body defining a plane, and tines extending from the body transversely with respect to the plane, the tines biased towards a planar configuration. The clip includes expandable elements disposed along its periphery that are biased to expand from compressed to expanded states for increasing a diameter of the clip upon deployment. The clip is provided within a housing slidably mounted on an introducer sheath. The sheath is introduced through a puncture into a blood vessel, and after a procedure is performed via the sheath, the housing is advanced into the puncture and the clip deployed until the tines engage tissue adjacent the opening in the vessel wall. The sheath is withdrawn from the patient, leaving the clip in place. The tines at least partially move towards the planar configuration to pull the engaged tissue together and close the opening.
Generally cardiac. Cancers are very rare and the possibility of being benign is present ..but after the biopsy will be taken..even if it is cancerous and its growth rate is not high..it can be treated with targeted radiotherapy and chemotherapy …The doctor will use a local anesthetic to numb the area of your neck. A plastic introducer sheath (a short, hollow tube through which the catheter is placed) is inserted through a small incision and into a blood vessel in the neck. A bioptome is inserted through the sheath and threaded to the right ventricle. X-rays, called fluoroscopy, are used… Read more » ...
Lizzie Rutherford Coleman, born 8 Mar 1858, died 20 Apr 1934, bur. 21 Apr 1934 - Descendents of John (Jno the Weaver) McBurney 1811-1872
0059] Although conventional wisdom until now has been to reduce the perceived frictional forces, it has been unexpectedly found that the inner housing and the outer housing of embodiments according to the present invention allow the strain that is induced by the displacement of parts of the soft inner seal elements is allowed to fully recover and maintain hemostasis because of the seal element surrounding stiff outer housing. The strain recovery provided by the interaction between the inner and outer housings reduces the extent to which the operator of the introducer sheath feels an increased amount of frictional resistance that is generated between the seals and the implement or device. In other words, it has unexpectedly been found that embodiments according to the present invention provide an acceptable frictional resistance feel when using a wide range of diameters of implements and devices while still providing complete hemostasis across the entire range of diameters. In addition, it has ...
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An 810 nm laser with a minimum of 15 W output power is used. Alternatively, a 980 nm laser can be used also with 15 W minimum output power. A 600 micron optical fibre is needed together with a guide wire introducer sheath and needle for percutaneous perforation.. Prior to treatment the SFJ and GSV are mapped through use of colour duplex ultrasound.. The guide wire introducer sheath is introduced into the GSV - at level with the knee or the lower part of the thigh. The fibre is advanced via the introducer sheath until the fibre tip is positioned 1-2 cm distal to the SFJ. A red guiding light emitted from the fibre tip provides a helpful indication of the tip position. Prior to release of the laser beam, the exact tip position is controlled carefully by use of ultrasound.. When laser is delivered by the introduced fibre, heating of the blood leads to formation of a steam bubble. That is, the effect of the laser is not achieved through contact with the wall of the blood vessel, but rather by ...
A colon lipoma is a remarkably rare tumor. In most cases, the tumors are asymptomatic and small in size, need to be differentiated from malignant tumors, and do not need any special treatment. Selection of the right surgical strategy depends on the status of bowel, as well as the size and the location of tumor. We encountered two patients with giant submucosal lipomas that had induced intussusceptions: one with a lipoma in the transverse colon and the other with a lipoma in the ascending colon. The diagnoses were made by using histological examinations ...
[Stenosing ganglioneuromatosis of the small intestine with ileus and ileal rupture].: Report on a 64-year-old man who presented with ileus and rupture of the il
NOTE: This product contains Di(2-ehylhexyl) phthalate (DEHP). Togo Medikit has conducted a Chemical Safety Assessment of DEHP in this device based on currently known acceptable exposure limits for sensitive populations (children and pregnant/nursing women), and has determined that the potential exposure is below the known acceptable exposure limits for the device when used in accordance with the indications and instructions for use.. ...
By L. Knut. The Stefan University.. As long as the needle is directed superficial until it is well aligned with the x-ray beam (see toward the final target buy generic vantin 200mg on line, needle advancement continues until Fig order cheap vantin on line. If the needle is coaxial but does not beam when the hub of the needle is superimposed on the tip lie over the final target order genuine vantin online, the needle should be removed and and appears as a radiolucent circle. Some examples a coaxial technique, small changes in needle direction can Chapter 1 Basic Techniques for Image-guided Injection 5 Figure 1-2. The Tuohy needle is among the most the most common needle used by many practitioners for image- common needles for interlaminar epidural injection using a guided injection (22-gauge with black hub, 25-gauge with light loss-of-resistance technique. The needles orifice is aligned blue hub; tip of 22-gauge needle is shown at various angles of rota- nearly perpendicular to the shaft to ...
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
Effect of Anatomical Distribution of Mast Cells on Their Defense Function against Bacterial Infections: Demonstration Using Partially Mast Cell deficient tg/tg ...
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Has anyone heard or experimented with float tanks as an intervention? Ive heard it can be beneficial, and it seems to make sense. REST or restrictive environmental stimulus therapy indicates that it could be beneficial for individuals who struggle with sensory elements by lowering the frequency of brain waves, increasing neurochemicals for joy and decreasing stress hormones. In addition, the solution of magnesium sulfate can be beneficial by cleansing and detoxifying. Just wondering if anyone has tried this ...
A catheter is disclosed which is capable of cutting obstructive tissue from a vessel of a living body while shielding a portion of the wall of the vessel from being exposed to the cutting blade at the catheters distal end. An essentially continuous outer surface at the catheters distal end allows it to be readily advanced through an introducer sheath and through a tight stenosis in an artery. The shield at the catheters distal end could subtend an arc from as little as 45 degrees to as large as 270 degrees depending on the extent of the vessel wall that is to be protected from being cut. A vacuum source at the catheters proximal end can cause a suction to exist at a cutout at the catheters distal end in order to pull obstructive tissue into the cutout as the cutting cylinder is pulled back in a retrograde direction, this suction being capable of enhancing the removal of the obstructive tissue.
A splittable medical valve is disclosed that is configured with a interfacing region that permits the valve to be placed over or inside of a tubular medical device, such as a splittable introducer sheath, to prevent loss of bodily fluids and/or reduce ingress of air-borne pathogens. The valve further includes a sealing element configured to accept passage of a medical device, such as a catheter, sheath, pacemaker lead, or other ancillary device therethrough, whereby the valve body is split along one or more lines or fissure to allow removal of the valve from around the ancillary device.
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[173 Pages Report] Interventional Cardiology Devices Market categories the Global market by type (Angioplasty, Catheters, Plaque Modification (Atherectomy, Thrombectomy), Hemodynamic Flow Alteration (Embolic Protection, Total Occlusion), Guidewire, Introducer Sheath)) & Geography
This channel includes news, techniques and new technology innovations for radial access, also called transradial access or radial artery access. This concerns the location of introducer sheaths and vascular access for interventional procedures. Radial access is supported to result in fewer complications compared to femoral access.
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RelA/p65 is a main subunit of nuclear factor-kappaB (NF-kappaB) that regulates expression of genes involved in cell growth and survival, stress response, and inflammation, but its oncogenic or tumor-suppressive function in tumorigenesis has been highly controversial. Hundreds of NF-kappaB inhibitors have been developed for targeted cancer therapy, but fail to achieve anticipated anticancer efficacy. Complexity of posttranslational modifications may contribute to tumorigenic diversity of RelA/p65, but mechanisms of action remain unclear. Here we show that phosphorylation of RelA/p65 at Ser536 functions as a tumor suppressor. In normal human colon mucosa, RelA/p65 phosphorylation at Ser536 is gradually increased with the maturation and apoptotic shedding of cryptic cells, but the phosphorylation is significantly decreased in colon tumors. In RelA/p65-silenced breast and colon cancer cells, reconstitution of a constitutively active RelA/p65, whose Ser536 was replaced by aspartic acid (named p65/S536D),
Method and apparatus for providing an introducer for transcutaneous placement of at least a portion of an analyte sensor through the skin of a patient is provided.
BioCardia®, Inc. [OTC: BCDA], a leader in the development of comprehensive solutions for cardiovascular regenerative therapies, today announced its 510(k) submission for U.S. Food and Drug Administration (FDA) clearance of the AVANCE™ steerable introducer, designed for introducing var...
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Is there any reason for the different spacing before the colons in the attached typeset formula? I have made sure that there is no space/* whatsoever between the subindex and the colon. Strange. A ...
OK, a single colon follows an access specifier, such as public: or private: or protected:, right? Are there any other situations in which a single col
Periods, colons, and semicolons all have the ability to stop a sentence in its tracks, but for very different purposes. In this lesson, learn how...
The colon is a mark of punctuation (:) used after a statement that introduces a quotation, an explanation, an example, or a series.
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... many casual mentions of the left colon chiefly concern the descending colon. The descending colon begins at the splenic flexure ... the descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. The function of ... Cancer of the descending colon is a serious disease. A person can have colon cancer yet have no symptoms in the early stages. ... The descending colon is on the left side of the body (barring any malformations). The term left colon is hypernymous to ...
The descending colon laterally (further left). Peritoneal recesses Paracolic gutters Anatomy photo:37:14-0200 at the SUNY ... This space is defined by: The ascending colon and caecum laterally (further right). The transverse colon superiorly. The root ... Paracolic gutters are recesses between the abdominal wall and the colon. These gutters are clinically important because they ... spaces in the abdominal cavity between the colon and the root of the mesentery. There are two paramesenteric gutters; the left ...
The left colic vein drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its ... Ascending branch Descending branch Ronald W. Dudek; Thomas M. Louis (11 February 2014). High-YieldTM Gross Anatomy. Lippincott ...
The descending and sigmoid colon are typically involved. Biopsies of the affected area and the unaffected rectum confirm the ... Computed tomography of the abdomen is not routinely necessary, but may show thickening or inflammation in the distal colon ( ... Fecal calprotectin, a marker of colon inflammation, may be elevated in individuals with SCAD. Fecal calprotectin may assist in ... However, ulcerative colitis usually affects the rectum and inflammation in IBD extends to areas of the colon without ...
June 2004). "Brain activity during distention of the descending colon in humans". Neurogastroenterol. Motil. 16 (3): 299-309. ...
February 6, 1986: Rear Admiral Cristóbal Colón de Carvajal y Maroto and his driver; the Rear Admiral, descended from Cristóbal ... Asesinados en Madrid el vicealmirante Colón de Carvajal y su conductor en un atentado en el que fue herido el comandante ... Colón. June 17, 1986: 3 members of Spanish army are shot dead inside a car while driving through Madrid. July 14, 1986: Plaza ...
... colon and rectum, each 2 patients; and stomach and esophagus, no patients. Lesions were limited to the second part of the ... descending) part of the duodenum, 54 patients; combined third (i.e. horizontal or inferior), and fourth (i.e. ascending) part ...
At the colon, it divides into a descending branch and an ascending branch. The descending branch anastomoses with the ileocolic ... The right colic artery supplies the ascending colon. In a right hemicolectomy to remove the caecum and the ascending colon, the ... toward the middle of the ascending colon. Sometimes, it lies at a higher level, and crosses the descending part of the duodenum ... It supplies the ascending colon. It may be removed in a right hemicolectomy. The right colic artery is a branch of the superior ...
People with colostomies who have ostomies of the sigmoid colon or descending colon may have the option of irrigation, which ... Other locations include the ascending, transverse, and descending sections of the colon. Pouches and the stick-on appliances to ... Some common reasons are: A part of the colon has been removed, e.g. due to colon cancer requiring a total mesorectal excision, ... A part of the colon has been operated upon and needs to be 'rested' until it is healed. In this case, the colostomy is often ...
He had a number of operations, and finally his descending colon was removed. Again his health improved. McCollum was blind in ...
The lateral boundary of the retroperitoneum is defined by the ascending and descending colon. The retroperitoneum can be ...
He is a colon cancer survivor, having been diagnosed in May 2010. He received six weeks of radiation and chemotherapy, and ... surgery to remove part of his colon, followed by more chemotherapy through early 2011. He is Jewish and descended from Russian ... he became the first president ever to call for a crowd to descend on the capital city to block the constitutional transfer of ...
Sigmoidocele is a prolapse of peritoneum that contains a section of sigmoid colon. In females, these prolapses usually descend ... Descending perineum syndrome If the perineum descends >4 cm, descending perineum syndrome may be diagnosed. Fecal incontinence ... al.], senior editors, Bruce G. Wolff ... [et (2007). The ASCRS textbook of colon and rectal surgery. New York: Springer. pp. 47 ...
... which supply the descending and sigmoid parts of the colon; and the superior hemorrhoidal plexus, which supplies the rectum and ...
Thus, patients without adequate collateralization are at risk for ischemia of the descending and sigmoid colon. Bloody diarrhea ... If blood flow to the colon drops by more than about 50%, ischemia will develop. The arteries feeding the colon are very ... The colon receives blood from both the superior and inferior mesenteric arteries. The blood supply from these two major ... Finally, a shock phase can develop as fluids start to leak through the damaged colon lining. This can result in shock and ...
The rectum receives fecal material from the descending colon, transmitted through regular muscle contractions called ... The rectum joins with the sigmoid colon at the level of S3, and joins with the anal canal as it passes through the pelvic floor ... Colon and Rectum" (PDF), AJCC Cancer Staging Atlas, American Joint Committee on Cancer, 2006, p. 109 Wolff BG, Fleshman JW, ... The rectum is a continuation of the sigmoid colon, and connects to the anus. The rectum follows the shape of the sacrum and ...
Payr's disease is constipation due to kinking of an adhesion between the transverse and descending colon. Also a tool used in ...
The four sections of the colon are: the ascending colon, transverse colon, descending colon, and sigmoid colon. These sections ... Of the colon, the ascending colon, descending colon and rectum are retroperitoneal, while the cecum, appendix, transverse colon ... The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. One function of ... The lymph from the distal one-third of the transverse colon, the descending colon, the sigmoid colon, and the upper rectum ...
This is done by adding additional :[bootstrap]:[prob] fields after the length; fields can be left empty as long as the colons ... production in those cases where having the entire tree descended from nowhere is permitted; this captures the replaced ... An unquoted string may not contain blanks, parentheses, square brackets, single_quotes, colons, semicolons, or commas. ... and colon) are prohibited. The Tree → Subtree ";" production is instead the Tree → Branch ";" ...
They drain the descending colon and sigmoid parts of the colon and the upper part of the rectum. Colorectal cancer may ...
The regions supplied by the IMA are the descending colon, the sigmoid colon, and part of the rectum. Proximally, its territory ... The SMA and IMA anastomose via the marginal artery of the colon (artery of Drummond) and via Riolan's arcade (also called the " ... All these arterial branches further divide into arcades which then supply the colon at regular intervals. The IMA is ... supplying the large intestine from the distal transverse colon to the upper part of the anal canal. ...
... transverse and descending colons, the sigmoid colon and the rectum. Other vital organs inside the abdomen include the liver, ... The left mid-Poupart line corresponds in its upper three-quarters to the inner edge of the descending colon. The right ... It indicates roughly the transverse colon, the lower ends of the kidneys, and the upper limit of the transverse (3rd) part of ... The abdominal cavity contains most organs of the digestive system, including the stomach, the small intestine, and the colon ...
It descends into the pelvis between the layers of the mesentery of the sigmoid colon, crossing the left common iliac artery and ... It divides, opposite the third sacral vertebra into two branches, which descend one on either side of the rectum. About 10 or ... The superior rectal artery (superior hemorrhoidal artery) is an artery that descends into the pelvis to supply blood to the ... THE COLON", The Digestive System (Second Edition), Churchill Livingstone, pp. 171-182, ISBN 978-0-7020-3367-4, retrieved 2021- ...
In the caecum, the ascending colon, the descending colon and sigmoid colon the positions of these bands are fixed. The taenia ... descending and sigmoid colon, but is situated on the anterosuperior surface of transverse colon where layers three and four of ... descending and sigmoid colon, but is placed inferiorly in the transverse colon. The taenia mesocolica is present on the ... descending and sigmoid colon, but is placed posteriorly on transverse colon at the site of attachment of transverse mesocolon. ...
The hindgut contains the distal half of the transverse colon, descending colon, sigmoid colon, rectum, and superior anal canal ... The midgut contains portions of the duodenum (distal), cecum, appendix, ascending colon, and first half of the transverse colon ... colon cancer Other: pneumonia, Fitz-Hugh-Curtis syndrome Left upper quadrant Splenomegaly Colon: bowel obstruction, functional ... sigmoid colon volvulus, bowel obstruction, gas accumulation, Toxic megacolon Right low back pain Liver: hepatomegaly Kidney: ...
The left colic artery is a branch of the inferior mesenteric artery distributed to the descending colon, and left part of the ... transverse colon. It ends by dividing into an ascending branch and a descending branch; the terminal branches of the two ... After a short but variable course, it divides into an ascending branch and a descending branch. The ascending branch passes ... Its terminal branches form anastomoses with those of the middle colic artery; it also forms anastomoses with the descending ...
In front of the pancreas sits the transverse colon. The pancreas narrows towards the tail, which sits near to the spleen. It is ... This ampulla opens into the descending part of the duodenum. The opening of the common bile duct into main pancreatic duct is ... The peritoneum sits on top of the body of the pancreas, and the transverse colon in front of the peritoneum. Behind the ... In front sits the peritoneal membrane and the transverse colon. A small uncinate process emerges from below the head, situated ...
The small intestine surrounded by the ascending, transverse, and descending colon, and the paracolic gutters are contained ... The peritoneal cavity is divided by the transverse colon (and its mesocolon) into an upper supracolic compartment, and a lower ... The peritoneal cavity is divided into two compartments - one above, and one below the transverse colon. ...
Lateral reflection of posterior parietal peritoneum of abdomen over the mesentery of the ascending and descending colon. The ...
... down the lateral aspect of the ascending colon, and around the cecum. It is continuous with the peritoneum as it descends into ... The main paracolic gutter lies lateral to the colon on each side. A less obvious medial paracolic gutter may be formed, ... paracolic gutters are peritoneal recesses on the posterior abdominal wall lying alongside the ascending and descending colon. ... The right (lateral) paracolic gutter runs from the superiolateral aspect of the hepatic flexure of the colon, ...
Soldiers descended from the choppers and arrested the employees working at the ranch, but Guzmán was nowhere to be found. ... Colón Navar, Brenda (26 December 2013). "Joaquín 'El Chapo' Guzmán might have suffered a heart attack". San Diego Red. Archived ...
Insertion of Alu elements in the human genome is associated with breast cancer, colon cancer, leukemia, hemophilia, Dent's ... Pseudogenes are generally functionless as they descend from processed RNAs independent of their evolutionary-context which ...
She had been born in Barcelona yet she descended from one of the most prominent noble families of France, which had been ... María del Pilar De la Cerda y Gand-Villain Rochefoucauld, (20 October 1816 - 28 February 1882), married to Pedro Colón de ...
"He was descending to make a landing and was within 200 feet of the ground when the machine fell." Knocked unconscious by the ... 2 May A U.S. Army seaplane en route on afternoon flight from Balboa, Panama to France Field, near present-day Colón, Panama, ... "In descending he lost control." The 28 January 1911 issue of Flight states that the "Motor stopped and machine was smashed; he ... Thomas was seen to wave to men on the field as the plane descended. Suddenly it fell, nose down, into a pond of mud and water, ...
"Cristóbal Colón y el descubrimiento de América" (Volume I). Salvat editores, s.a., 1945. pp. 139-157. Retrieved 2011-02-22. (in ... He tries to condition his readers, speaking of a noble family, from which his progenitor was presumably descended. He seeks it ... If the name had been "Colón", the author of the map would have translated this as Qolōn and would not have written Qolōnbō (" ... in Spanish) "Colón era un barcelonés que camufló su origen." La Hemeroteca de La Vanguardia, 2009. Retrieved 2010-03-15. ...
... spokesmen for the colons raised the specter of the European electorate's being submerged by a Muslim majority. Colon ... Referring to the urban population often Arab and descended or mixed with Moorish refugees from Al-Andalus. Bedouins (البدو, "Al ... The colons also had powerful allies in the French National Assembly, the bureaucracy, the armed forces, and the business ... The tensions between the Muslim and colon communities exploded on May 8, 1945, V-E Day, in an outburst of such violence as to ...
August 4, 1989 - Cuba - The head-on collision of two passenger trains at Colón kills 32 people and injures 17. August 5, 1989 ... A Southern Pacific Railroad freight train derails on Duffy Street after descending the very steep Cajon Pass, killing two crew ...
The two layers of the greater omentum descend from the greater curvature of the stomach and the beginning of the duodenum. They ... passing in front of the small intestines and doubles back to ascend to the transverse colon before reaching to the posterior ... and ascending as far as the transverse colon, where they separate and enclose that part of the intestine. These individual ... ligament-extends to the underside of the left dome of the diaphragm Gastrocolic ligament-extends to the transverse colon ( ...
... and it reaches the colon. The bacteria in the colon, mixed with the lactose, cause acidity in stools. Stools passed after the ... One was that European-descended populations have a very low incidence of lactose intolerance and an extensive cultural history ... passes intact into the colon.[citation needed] Bacteria in the colon can metabolise lactose, and the resulting fermentation ... The unabsorbed sugars and fermentation products also raise the osmotic pressure of the colon, causing an increased flow of ...
Colón Semenza; Gregory M. Colón Semenza (eds.). Milton in Popular Culture. Springer. ISBN 1403983186. Ocker, J. W. (2012). The ... Schumacher planned a sequence in which Pitt would descend into the New York subway system, which would be modeled on the ... Brown, Eric C. (2006). "Popularizing Pandaemonium: Milton and the Horror Film". In L. Knoppers; G. Colón Semenza; Gregory M. ... Colón Semenza (eds.). Milton in Popular Culture. Springer. ISBN 1403983186. De La Torre, Miguel A.; Hernández, Albert (2011). ...
This behavior is explained by the descending latitudinal order, at except for the El Tucuco station (2,032.9 mm), whose ... and Colón (6.71%), which occupy more than 50% of the total state area. The region has great economic resources among which are ...
The next day in the afternoon a patrol of fifty Spanish cavaliers descended out of the mountains from Caracas and saw that the ... The Venezuelan composer Eric Colon wrote an opera called El Caballero de Ledesma that premiered on 5 May 1979, in a sold-out ...
Assume f : X → Y {\displaystyle f\colon X\to Y} and g : Y → Z {\displaystyle g\colon Y\to Z} are morphisms of schemes and f is ... which does not descend to X. fpqc morphism Relative effective Cartier divisor, an example of a flat morphism Degeneration ( ... Let f : X → Y {\displaystyle f\colon X\to Y} be a morphism of schemes. For a morphism g : Y → Y {\displaystyle g\colon Y\to Y ... colon Y'\to Y} , then the fiber product f × g : X × Y Y ′ → Y ′ {\displaystyle f\times g\colon X\times _{Y}Y'\to Y'} is flat or ...
American film and television actress of Jewish and Puerto Rican descend Eddie Velez (1958-) American actor of Puerto Rican ... American actor of Mexican and Irish descent Liza Colón-Zayas (1972-) American actress and playwright of Puerto Rican descent ... Spanish and Native American descend James Vasquez (1972-) American actor and director to a Mexican father Sofía Vergara (1972 ... Dominican-born American actor Míriam Colón (1936-2017) Puerto Rican-born American actress Linda Cristal (1931 - 2020) ...
... colon \Omega ^{k}(P,V)\rightarrow \Omega ^{k+1}(P,V)\,} and so, for k=0, it defines a differential operator φ ∘ d : Ω 0 ( P , V ... so that it descends to a section of the bundle V. For (1), the ambiguity in selecting a right-invariant lift of X is a ... colon TP\to {\mathfrak {h}}} on P, with values in the Lie algebra h {\displaystyle {\mathfrak {h}}} of H, such that Ad ( h ) ( ... colon \Omega ^{k}(P,V)\cong \Omega ^{0}(P,V\otimes \bigwedge \nolimits ^{k}{\mathfrak {g}}^{*})} given by φ ( β ) ( ξ 1 , ξ 2 ...
The sigmoid arteries are 2-5 branches of the inferior mesenteric artery that are distributed to the distal descending colon and ... the sigmoid colon.: 1197 The sigmoid arteries course obliquely inferior-ward and to the left, passing posterior to the ...
The position of Sachem descends through families and are allocated by the senior female clan heads, though, prior to the ... Joel Colón-Ríos (2012). Weak Constitutionalism: Democratic Legitimacy and the Question of Constituent Power (Routledge Research ...
Also in 2003, Carlotta's 15-year-old goddaughter Adriana Colón arrives in Llanview; by 2004 it is revealed that Adriana is ... Todd is suspected but it is ultimately revealed that Powell, threatened by Rebecca's attraction to Todd, had descended into ...
the partnership formed by Alexander Hoyle and John Doran continuing the unbroken succession descending from original Cram ... Colon, Panama, 1910 Edward Courtland Gale Mausoleum - Troy, NY, 1914 Woodrow Wilson Memorial - Washington DC, 1925 Memorial ...
Hundreds of people descended on Presley as he stepped from the bus; photographers then accompanied him into the installation. ... By this point he suffered from glaucoma, hypertension, liver damage, and an enlarged colon, each magnified-and possibly caused- ...
... colon \operatorname {Fin} \to k-\mathrm {mod} } , we get a simplicial module by composing F with S 1 {\displaystyle S^{1}} . Δ ... there exists a descending N {\displaystyle \mathbb {N} } -filtration F ∙ {\displaystyle F_{\bullet }} on H H n ( A / k ) {\ ...
The match centered around Maryse keeping her distance from James before descending to the floor in an attempt to use a can of ... The Colóns, and Rhodes and DiBiase (collectively known as The Legacy). Two weeks following the event on the July 6 episode of ...
... colon MeSH A03.556.124.526.356.333 - ascending colon MeSH A03.556.124.526.356.500 - descending colon MeSH A03.556.124.526. ... colon MeSH A03.556.249.249.356.333 - ascending colon MeSH A03.556.249.249.356.500 - descending colon MeSH A03.556.249.249. ... 356.668 - sigmoid colon MeSH A03.556.124.526.356.834 - transverse colon MeSH A03.556.124.526.767 - rectum MeSH A03.556.124.684 ... 356.668 - sigmoid colon MeSH A03.556.249.249.356.834 - transverse colon MeSH A03.556.249.249.767 - rectum MeSH A03.556.249.750 ...
Therapsids descended from sphenacodonts, a primitive synapsid, in the middle Permian, and took over from them as the dominant ... a large intestine which bears a true colon after the cecum, endothermy, a hairy, glandular and thermoregulatory skin (which ... Within a few million years, two important amniote lineages became distinct: synapsids, from which mammals are descended, and ... sauropsids, from which lizards, snakes, turtles/tortoises, crocodilians, dinosaurs, and birds are descended. The earliest known ...
He was also said to have been descended from the Khoi interpreter known as Krotoa or Eva. When de Klerk was twelve years old, ... he underwent surgery for a malignant tumor in his colon. His condition deteriorated sharply, and he underwent a tracheotomy ...
It is adapted for climbing and descends to the ground head-first with the hindfeet holding on to the middle of the tree trunk. ... no noticeable divide between the ileum and colon, and no caecum. The red panda inhabits Nepal, the states of Sikkim, West ...
The mesentery associated with the ascending colon and descending colon is resorbed, bringing these parts of the colon into ... The descending colon occupies a similar position on the left side. During these topographic changes, the dorsal mesentery ... These are the transverse mesocolon attaching to the transverse colon, the sigmoid mesocolon attaching to the sigmoid colon, the ... the ascending colon and the initial two-thirds of the transverse colon. As the foetus grows larger, the mid-gut loop is drawn ...
A majority of Afro-Caribbean people descend from peoples in the regions of West Africa and western Central Africa. In ... Nieves-Colon, Maria A. (15 December 2021). "Anthropological genetic insights on Caribbean population history". Evolutionary ...
... dentition depressor anguli oris muscle dermatoglyphics dermatome dermis descendens cervicalis descending aorta descending ... pericardium sesamoid bone sex organ Sharpey's fibres short ciliary nerves shoulder shoulder blade shin sight sigmoid colon ... nerve coeliac coelom coeruleus collar bone collateral eminence collateral fissure collateral trigone colliculus collum colon ... trachea tract of Lissauer tractus solitarius tragus transverse cervical artery transverse cervical nerve transverse colon ...
How effective are second-generation colon capsule endoscopes at evaluating the severity of mucosal inflammation in patients ... Sigmoid colon (n). 2. Descending colon (n). 3. Transverse colon (n). 2. ... Ascending colon. Transverse colon. Proximal left-sided colon. Distal left-sided colon. ... Background and Aim Colon capsule endoscopy has already been used for colon visualization and detection of polyps but its ...
Basaloid carcinoma of descending colon.. Authors: Jaswal, T S. Gupta, Sumiti. Singh, Sunita. Marwah, Nisha. Marwah, Sanjay. ... Jaswal TS, Gupta S, Singh S, Marwah N, Marwah S, Arora B. Basaloid carcinoma of descending colon. Indian Journal of ... At laparotomy, she had a circumferential obstructing growth in the descending colon, with hemorrhagic ascites and metastases in ...
CT abdomen s/o Large bowel obstruction Colonoscopy done showed stricture in Descending colon... Bx taken s/o Adeno Ca ... Malignant stricture in Descending colon. A male aged 60 years Chief Complaints Severe Pain Abdomen (x 10 days) Unable to pass ... Investigations CT abdomen s/o Large bowel obstruction Colonoscopy done showed stricture in Descending colon... Bx taken s/o ...
Abdomen, Abdominal pain, Cancer, Colon, Colonoscopy, Colorectal cancer, Department of Health (United Kingdom), Descending colon ... They also use it to look for early signs of cancer in the descending colon and rectum. With flexible sigmoidoscopy, the ... You will feel better afterward when the air leaves your colon.. Preparation. The colon and rectum must be completely empty for ... called the sigmoid or descending colon. Physicians may use the procedure to find the cause of diarrhea, abdominal pain, or ...
Keyword Descending colon. #. Image group title. View. 14. Inflammatory tumour of descending colon, CT colonography. ...
The large bowel is also called the large intestine or colon. ... The colon is attached to the outer wall of your belly. Stool ... Ascending colectomy; Descending colectomy; Transverse colectomy; Right hemicolectomy; Left hemicolectomy; Low anterior ... The large bowel is also called the large intestine or colon.. *Removal of the entire colon and the rectum is called a ... Colon and rectum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. ...
Four cases of laparoscopic colectomy for sigmoid colon and rectal cancer with persistent descending mesocolon. Overview of ... New article: Four cases of laparoscopic colectomy for sigmoid colon and rectal cancer with persistent descending mesocolon. ...
Colonic biopsy (descending colon). Lymphoepithelial lesions are strongly associated with mucosa-associated lymphoid tissue ... Colonic biopsy (descending colon). Lymphoepithelial lesions are strongly associated with mucosa-associated lymphoid tissue ...
... and answers will help you understand the medical language used in the pathology report you received for your biopsy for colon ... The ascending colon, transverse colon, descending colon, and sigmoid colon are other parts of the colon after the cecum. The ... What if my report mentions the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, or rectum?. These are ... What is a polyp in the colon?. A polyp is a projection (growth) of tissue from the inner lining of the colon into the lumen ( ...
Colonic biopsy (descending colon). Lymphoepithelial lesions are strongly associated with mucosa-associated lymphoid tissue ... Colonic biopsy (descending colon). Lymphoepithelial lesions are strongly associated with mucosa-associated lymphoid tissue ... Surgery may be considered for certain sites (ie, thyroid, colon/small bowel and lumpectomy for breast). Rituximab and ...
Categories: Colon, Descending Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 1 ...
descending (left) 863.43. *. with open wound into cavity 863.53. *. multiple sites 863.46. *. with open wound into cavity ... Short description: TRANSVERSE COLON INJ-CL.. *ICD-9-CM 863.42 is a billable medical code that can be used to indicate a ... Injury to transverse colon without open wound into cavity. * ... colon 863.40. *. with*. open wound into cavity 863.50. *. ... 2015/16 ICD-10-CM S36.501A Unspecified injury of transverse colon, initial encounter ...
P. Meyer-Herbon, C. Brugnolaro, R. Frei, and M. C. Sulz, "Pyogenic granuloma of the descending colon: a rare cause of lower ... T. Nakaya, T. Tokunaga, S. Aono et al., "Pyogenic granuloma of the descending colon," Endoscopy, vol. 39, supplement 1, pp. ... T.-C. Chen, J.-M. Lien, K.-F. Ng, C.-J. Lin, Y.-P. Ho, and C.-M. Chen, "Multiple pyogenic granulomas in sigmoid colon," ... M. C. González-Vela, J. F. Val-Bernal, M. F. Garijo, and C. García-Suárez, "Pyogenic granuloma of the sigmoid colon," Annals of ...
However, no increased risk was found for cancer in the descending colon. Nor was there an increased risk of rectal cancer in ... There was no difference in the frequency of colon cancer in those who used this drug, suggesting that it is the impact of ... NEWS There is a clear link between taking antibiotics and an increased risk of developing colon cancer within the next five to ... You are here: Antibiotics increase the risk of colon cancer ger ökad risk för cancer i tjocktarmen ...
Large Colon (Tranverse): which is responsible for forming stool.. *Large Colon (Descending): which is responsible for forming ...
The rest of your large intestine (ascending and descending colon) was.... 4/20/2022 5:35 PM ...
Sigmoid colon between the descending colon and the rectum (at least 15 cm from the dentate) ... stage I colon cancer. stage II colon cancer. stage III colon cancer. adenocarcinoma of the colon. ... Left colon from the splenic flexure to the junction of the sigmoid and descending colon ... No acutely obstructed or perforated colon cancer requiring urgent surgery. *No transverse colon cancer (i.e., between distal ...
This surgical procedure removes the sigmoid colon and connects the descending colon with the anus. It can be done via open or ... What is a Sigmoid Colectomy Procedure for Colon Cancer?. ...
Your colon is an integral part of the digestive system, also known as your gastrointestinal tract (GI). ... Descending colon. *Sigmoid colon. *Rectum. *Anal canal. How Often You Have Bowel Movements Varies. Its a popularly thought ... Shankhprakashalana - Colon Cleansing with Yoga. By Jared McAllister on April 29, 2019 in Colon Cleanse Blog with 0 Comments ... 10 Surprising Colon Facts. By Jared McAllister on October 26, 2022 in Colon Cleanse Blog ...
Bowel wall thickness as a differentiating feature between ulcerative colitis and Crohns disease of the colon. Download Prime ... Measurement was possible in 84% of barium enemas, mainly in the descending colon. The maximum wall thickness associated with ... Measurement was possible in 84% of barium enemas, mainly in the descending colon. The maximum wall thickness associated with ... Bowel wall thickness as a differentiating feature between ulcerative colitis and Crohns disease of the colon.. Clin Radiol. ...
Inhibitory neuropeptides and intrinsic inhibitory innervation of descending human colon. Koch, T. R., Carney, J. A., Go, V. L. ...
The colon has three parts: the ascending colon and the transverse colon, which absorb fluids and salts; and the descending ... The colon extends from the cecum up the right side of the abdomen, across the upper abdomen, and then down the left side of the ... Bacteria in the colon help to digest the remaining food products.. *The rectum is where feces are stored until they leave the ...
colon, descending 60792 skeletal muscle 163430 placenta 80932 pancreas 79718 HeLa S3 32213 fetal heart 55979 yeast tRNA ... colon, transverse 62300 kidney 137204 lung 58777 liver 85484 leukemia, HL-60 48972 fetal brain 43774 yeast total RNA ... colon, ascending 40405 trachea 38285 lung, carcinoma, A549 27590 human DNA 500 ng 9541 ...
August 2004 Stage 4 Large colon tumor, grew through colon wall, engulfed overy. In lymph nodes. Totally obstructed. Emergency ... 3 polyps..2 in descending, 1 in rectum & inflammation at original cancer site. All benign /negative.. Chemo 12/8/09---Folfox 5 ... Colon resection in August of 2009, finished 11 round of chemo on Feb 8th, 2010 and had liver resection in March, 2010. ... Did you know staging has recently changed? Now the staging depends on how deep the tumor grew into the colon wall or had it ...
... enables the physician to look at the inside of the large intestine from the rectum through the last part of the colon. ... They also use it to look for early signs of cancer in the descending colon and rectum. With flexible sigmoidoscopy, the ... You will feel better afterward when the air leaves your colon.. Preparation. The colon and rectum must be completely empty for ... called the sigmoid or descending colon. Physicians may use the procedure to find the cause of diarrhoea, abdominal pain, or ...
The ascending colon is derived from the midgut. The gallbladder and stomach are derived from the foregut, and the descending ... Descending and sigmoid colons = receive blood from the inferior mesenteric artery and the parasympathetic nerve fibers from the ... The transverse colon passes anterior to the superior mesenteric artery and the third part of the duodenum. The other structures ... It is through this canal the testis normally descend. He is at greater risk for malignancy because it cannot be palpated during ...
The small intestine surrounded by the ascending, transverse, and descending colon, and the paracolic gutters are contained ... The peritoneal cavity is divided by the transverse colon (and its mesocolon) into an upper supracolic compartment, and a lower ... The peritoneal cavity is divided into two compartments - one above, and one below the transverse colon.[3] ...
  • Flexible sigmoidoscopy is not sufficient to detect polyps or cancer in the ascending or transverse colon (two-thirds of the colon). (findmeacure.com)
  • The ascending colon, transverse colon, descending colon, and sigmoid colon are other parts of the colon after the cecum. (cancer.org)
  • The peritoneal cavity is divided into two compartments - one above, and one below the transverse colon . (wikipedia.org)
  • The peritoneal cavity is divided by the transverse colon (and its mesocolon ) into an upper supracolic compartment , and a lower infracolic compartment . (wikipedia.org)
  • the Ascending Colon, Transverse Colon, Descending Colon and the Sigmoid Colon. (juicing-for-health.com)
  • Transverse colon: The second section goes across the abdomen from right to left. (healthlibrary.com)
  • The segment of large intestine between the cecum and the rectum including the ascending colon, the transverse colon, the descending colon, and the sigmoid colon. (citizendium.org)
  • It accompanies the superior mesenteric artery to the pancreas , small intestine ( duodenum , jejunum and ileum ), and large intestine as far as the left trisection of the transverse colon . (videohelp.com)
  • It supplies the colon from the left trisection of the transverse colon to the rectum . (videohelp.com)
  • The SMA gives rise to the ileocolic, right colic, and middle colic arteries, which supply the ileocecal region, the ascending colon, and the proximal transverse colon, respectively. (medscape.com)
  • The left colic artery, arising from the IMA, supplies the left portion of the transverse colon and the descending colon. (medscape.com)
  • The transverse colon runs across the abdomen. (car-ix.net)
  • The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON . (bvsalud.org)
  • An area of increased attenuation within the mesenteric fat in the right upper quadrant surrounding an area of diminished attenuation was noted, arising from the transverse colon (Figures 3 and 4). (medscape.com)
  • As no metastatic lesions were found other than the tumor of transverse colon, we performed laparoscopic-assisted segmental colon resection. (bvsalud.org)
  • A small incision was placed in the umbilical region, and the transverse colon was extracted from the umbilical region after dissection of the adhesions by single-incision laparoscopic surgery. (bvsalud.org)
  • The transverse colon containing the mass lesion was partially resected extracorporeally and reconstructed with a functional end-to-end anastomosis. (bvsalud.org)
  • wall, large colon, and cecum. (cdc.gov)
  • The cecum is the beginning of the colon, where the small intestine empties into the large intestine. (cancer.org)
  • In comparison with the descending colon, sigmoid colon, and rectum, the cecum and ascending colon are saccular, are larger in diameter, and have thinner walls. (medscape.com)
  • polyposis of sigmoid and descending colon, chronic enterorrhagia. (zp.ua)
  • The screening barium enema performed 3 years ago (Figure 6) shows multiple diverticula in the sigmoid and descending colon (arrowheads). (medscape.com)
  • Rectal contrast radiography anteroposterior view with diluted iohexol shows normal filling of the narrowed rectum with minimal distension of the distal sigmoid colon. (ispub.com)
  • Rectal contrast radiography: showed normal filling of the rectum with no filling defect however a filling defect was noted at the descending colon - sigmoid colon junction. (ispub.com)
  • And the longer the waste is in contact with the wall of the colon, not only does it get reabsorbed into the blood stream, it begins to mutilate the wall membrane that eventually leads to leaky gut , colon or rectal cancer. (juicing-for-health.com)
  • This booklet is for you if you have or someone close to you has Colon or Rectal Cancer. (healthlibrary.com)
  • Most colon and rectal cancers start in the innermost lining of the bowel and develop from small growths called polyps. (healthlibrary.com)
  • Seminars in Colon and Rectal Surgery. (wustl.edu)
  • Background and Aim Colon capsule endoscopy has already been used for colon visualization and detection of polyps but its applicability to inflammatory bowel disease is still unconfirmed. (medscape.com)
  • The extent of colon resection is identical for both arms. (clinicaltrials.gov)
  • ascending colon completely removed & resection. (cancer.org)
  • Colon resection in August of 2009, finished 11 round of chemo on Feb 8th, 2010 and had liver resection in March, 2010. (cancer.org)
  • The postoperative course was uneventful and the patient was discharged 8 days after surgery, and is alive for 10 months after the segmental colon resection followed by chemotherapy. (bvsalud.org)
  • If anything unusual is in your rectum or colon, like a polyp or inflamed tissue, the physician can remove a piece of it using instruments inserted into the scope. (findmeacure.com)
  • What is a polyp in the colon? (cancer.org)
  • A polyp is a projection (growth) of tissue from the inner lining of the colon into the lumen (hollow center) of the colon. (cancer.org)
  • An adenoma is a polyp made up of tissue that looks much like the normal lining of your colon, although it is different in several important ways when it is looked at under the microscope. (cancer.org)
  • In a preclinical study, mouse models of colon cancer carrying an APC 716del mutation had reduced polyp formation after treatment with MF tricyclic ( PMID: 23843721 ). (jax.org)
  • The vagus nerve supplies the parasympathetic tone from the upper gastrointestinal (GI) tract to the splenic flexure, and the sacral parasympathetic nerves (S2 to S5) supply the left colon, sigmoid, and rectum. (medscape.com)
  • Furthermore, adenomas in the splenic flexure and descending colon were more frequently missed in deep-sedated colonoscopy than in unsedated colonoscopy, particularly when performed by less experienced endoscopists. (bvsalud.org)
  • When is a colostomy required for colon cancer surgery? (human.com.sg)
  • Researchers found that both women and men who took antibiotics for over six months ran a 17 per cent greater risk of developing cancer in the ascending colon, the first part of the colon to be reached by food after the small intestine, than those who were not prescribed any antibiotics. (umu.se)
  • The small intestine surrounded by the ascending, transverse, and descending colon, and the paracolic gutters are contained within the infracolic compartment. (wikipedia.org)
  • Ascending colon, descending colon, and sigmoid colon located outside the thickened enhanced peritoneum. (diagnosticimaging.com)
  • Ascending colon: The first part of the colon starts at the bottom, right-hand side of the abdomen just after the small bowel and the appendix. (healthlibrary.com)
  • Material passes through the ascending, transverse, descending and sigmoid portions of the colon, and finally into the rectum. (medlineplus.gov)
  • The ascending colon travels up the right side of the abdomen. (car-ix.net)
  • The default is now to list comments in ascending order instead of descending order, and order=DESC must be set to list comments in descending order. (chessvariants.com)
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column. (jax.org)
  • [ 2 ] Mucosal inflammation in UC extends from the rectum to the proximal colon. (medscape.com)
  • Parasagittal reformat image showed a hypo dense filling defect in the proximal sigmoid colon with areas of irregularity of lumen. (ispub.com)
  • A male aged 60 years Chief Complaints Severe Pain Abdomen (x 10 days) Unable to pass stools H/o Loss of weight (x 1 month) Loss of Appetite Physical Examination Pall (+) P/A - Gurgling lump abdomen, BS (-) Investigations CT abdomen s/o Large bowel obstruction Colonoscopy done showed stricture in Descending colon. (curofy.com)
  • The growth pattern is only important because it helps determine when you will need your next colonoscopy to make sure you don't develop colon cancer in the future. (cancer.org)
  • They also use it to look for early signs of cancer in the descending colon and rectum. (findmeacure.com)
  • However, no increased risk was found for cancer in the descending colon. (umu.se)
  • Certain health conditions (such as colon cancer and inflammatory bowel disease) may require the removal of a person's colon. (coloncleansers.net)
  • The most sinister cause would be a narrowing of the rectum or descending colon due to an inflammatory or malignant process. (human.com.sg)
  • PURPOSE: Randomized phase III trial to compare the effectiveness of laparoscopic-assisted colectomy with open colectomy in treating patients who have colon cancer. (clinicaltrials.gov)
  • Compare the disease-free and overall survival rates of patients with colon cancer treated with laparoscopic-assisted colectomy vs open colectomy. (clinicaltrials.gov)
  • We report a case of colon metastasis from gastric cancer treated by laparoscopic-assisted segmental colectomy. (bvsalud.org)
  • The large bowel is also called the large intestine or colon. (medlineplus.gov)
  • Surgery may be considered for certain sites (ie, thyroid, colon/small bowel and lumpectomy for breast). (medscape.com)
  • In the colon, this material is made into a stool that is passed during a bowel movement. (coloncleansers.net)
  • Bartram CI, Herlinger H. Bowel wall thickness as a differentiating feature between ulcerative colitis and Crohn's disease of the colon. (unboundmedicine.com)
  • TY - JOUR T1 - Bowel wall thickness as a differentiating feature between ulcerative colitis and Crohn's disease of the colon. (unboundmedicine.com)
  • The colon and rectum make up the large bowel, which is part of our digestive system. (healthlibrary.com)
  • About two-thirds of cancers that develop in the large bowel occur in the colon and one-third occur in the rectum. (healthlibrary.com)
  • After the colon, the remaining waste matter, known as stools or faeces, is held in the rectum (back passage) until it s ready to be passed from the body through the anus as a bowel motion (stool). (healthlibrary.com)
  • The upper rectum is the section directly after the sigmoid colon, and the lower rectum is where the large bowel joins the anus. (healthlibrary.com)
  • In congenital stenosis, a narrow segment of colon is observed, but bowel continuity is maintained. (medscape.com)
  • Can bloating and irregular bowel movements be a sign of colon cancer in a 27 year old male? (human.com.sg)
  • How do doctors decide between surgery or stenting for a blocked bowel due to colon cancer? (human.com.sg)
  • With flexible sigmoidoscopy, the physician can see bleeding, inflammation , abnormal growths, and ulcers in the descending colon and rectum. (findmeacure.com)
  • At laparotomy, she had a circumferential obstructing growth in the descending colon, with hemorrhagic ascites and metastases in the liver and lymph nodes. (who.int)
  • Molecular investigation of a multisource compromised humans who may have or colon were observed macroscopi- outbreak of Crimean-Congo hemorrhagic close contact with animals. (cdc.gov)
  • The colon is approximately 5 feet long and is in the shape of an upside-down U that goes up one side of the abdomen, across the top, and down the other side. (coloncleansers.net)
  • Descending colon: The third section goes down the left hand side of the abdomen. (healthlibrary.com)
  • The appendix is a thin, tubular pouch, about 2 to 4 inches long in adults, which descends from the colon on the lower right side of the abdomen. (uexpress.com)
  • In this case, the axial CT images of the abdomen at the level of the pelvis (Figures 2 and 3) show acute diverticulitis of the sigmoid colon. (medscape.com)
  • The descending colon travels down the left abdomen. (car-ix.net)
  • The aim of this study was to assess the feasibility of evaluating the severity of mucosal inflammation in patients with ulcerative colitis (UC) using a second-generation colon capsule endoscope (CCE-2). (medscape.com)
  • 2 in descending, 1 in rectum & inflammation at original cancer site. (cancer.org)
  • Removal of all of the colon but not the rectum is called subtotal colectomy. (medlineplus.gov)
  • In preclinical trials, Sirolimus (rapamycin) was shown effective in reducing tumors in mouse models of familial adenomatous polyposis and colon cancer with APC deficient tumors ( PMID: 18768809 , PMID: 20080688 ). (jax.org)
  • Now the staging depends on how deep the tumor grew into the colon wall or had it broken through the wall. (cancer.org)
  • The postoperative pathological findings revealed tumor cells predominantly below the submucosal layer and partly showing the signet ring cell carcinoma, and the transvers colon tumor was diagnosed as a metastasis from gastric cancer. (bvsalud.org)
  • Flexible sigmoidoscopy (SIG-moy-DAH-skuh-pee) enables the physician to look at the inside of the large intestine from the rectum through the last part of the colon , called the sigmoid or descending colon . (findmeacure.com)
  • Here are 10 colon facts to help you become better acquainted with your large intestine, including the function and location of your colon, how long your intestines are, and more. (coloncleansers.net)
  • This surgery involves removing the colon and rectum and using the last part of the small intestine (the ileum) to create an internal pouch, which is typically J-shaped. (coloncleansers.net)
  • The colon is responsible for finishing the digestive process of digestion by absorbing water and electrolytes from food leaving the small intestine. (coloncleansers.net)
  • At the end of the small intestine, the food enters the large intestine (colon) for a final digestive process and finally, elimination. (juicing-for-health.com)
  • Unlike the small intestine that absorb foods and nutrients, the colon extracts water and electrolytes, and form what's left of the wastes into feces to be eliminated. (juicing-for-health.com)
  • It is not yet known which type of surgery is more effective for colon cancer. (clinicaltrials.gov)
  • How much does colon cancer surgery cost in Singapore, and is it Medisave claimable in private? (human.com.sg)
  • Colon cancer surgery is complex and requires a team of specialists, nurses and specialised equipment. (human.com.sg)
  • The epiploic appendages (variably termed "appendices epiploicae") are pedunculated adipose projections from the serosal surface of the colon. (medscape.com)
  • Patients with stage IV adenocarcinoma of the colon/rectum diagnosed from 2010 to 2013 were extracted from SEER data. (jnccn.org)
  • This large population-based study showed that among patients initially diagnosed with stage IV CRC, right-sided colon cancer was associated with greater risk of death compared with left-sided cancer, and KRAS mutations were only associated with risk of death in left-sided colon cancer. (jnccn.org)
  • The lower 6 thoracic segments supply the sympathetic tone to the right colon, whereas lumbar segments 1-3 supply the left colon. (medscape.com)
  • The axial section showed a heterogeneous lesion with both hypo and isodense foci giving a spongiform appearance with encroachment of the adjoining sigmoid colon causing filling defects. (ispub.com)
  • colonic stenosis is a condition in which a part of the colon is very narrow, resulting in a partial blockage. (medscape.com)
  • The colon is where water is absorbed as part of the digestive process and the rectum is where waste matter (stools or faeces) is held until it's ready to be passed. (healthlibrary.com)
  • CCE-2 procedure completion rate and the colon cleansing level with a 4-point grading scale (poor, fair, good, and excellent) were evaluated in Phase 2. (medscape.com)
  • A CCE procedure requires extensive, multi-step preparation [ 9 ] for colon cleansing and the capsule booster. (medscape.com)
  • The colon ends at the rectum, where waste is stored until it exits through the anus. (cancer.org)
  • If you have diarrhea, the stool hasn't been in your colon long enough to adequately absorb enough liquid to make the stool firm. (coloncleansers.net)
  • The scope transmits an image of the inside of the rectum and colon, so the physician can carefully examine the lining of these organs. (findmeacure.com)
  • The scope has a camera on the distal tip which enables the physician to carefully examine the lining of your colon. (bgapc.com)
  • There is a filling defect (star) at the junction of the descending colon and sigmoid colon. (ispub.com)
  • All cases were New Mexico residents diagnosed with invasive cancer of the colon (International Classification of Diseases for Oncology-Third Edition (ICD-O-3) topography codes C18.0, C18.2-C18.9, and C26.0), rectosigmoid junction (ICD-O-3 topography codes C19.9), or rectum (ICD-O-3 site codes C20.9). (cdc.gov)
  • Your colon then begins the process of eliminating the waste through the stool (feces). (coloncleansers.net)
  • Some people have so much compacted feces in the colon that the passage through which the feces are forced to travel is reduced to only a passage as thin as a pencil. (juicing-for-health.com)
  • One theory, examined in a 1988 study by Lee et al, is that increased sympathetic tone to the colon results in the inhibition of colonic motility. (medscape.com)
  • The colon is attached to the outer wall of your belly. (medlineplus.gov)
  • The maximum wall thickness in the control group with neoplasia measured in non-diseased colon, was 2 mm. (unboundmedicine.com)
  • As the wall tension of the colon increases, ischemia with longitudinal splitting of the serosa, herniation of the mucosa, and perforation (including iatrogenic perforation during open or laparoscopic procedures) can occur. (medscape.com)
  • Anyone who knows anything about the Spanish-American War, even as little as yours truly, knows after the declaration of war, the American Asiatic Fleet under Commodore Dewey descended on the antiquated Spanish fleet under Admiral Patricio Montojo in Manila Bay and like a cloud of hungry locusts literally chewed his wooden ships down to the water line. (wordpress.com)
  • It is important for your doctor to have a clear view of your colon during the examination, you will be given instructions from your physician as to the preparation to use prior to the examination. (bgapc.com)
  • Functions are denoted on CTBUH "Tallest Building" lists in descending order, e.g., "hotel/office" indicates hotel function above office function. (skyscrapercenter.com)
  • This is to make it explicit when comments are being listed in descending order. (chessvariants.com)
  • The colon is the final part of our digestive system, measuring about up to 6 feet long. (juicing-for-health.com)
  • Now I sit in another expanse, internal and metallic and mobile this time, descending the colon of the beast, a long smooth chromium turd sliding down down, to dump me downtown, as it were. (mathewlebowitz.com)