Colonic Neoplasms: Tumors or cancer of the COLON.Colon, Descending: The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.Colon, Sigmoid: A segment of the COLON between the RECTUM and the descending colon.Colon, Ascending: The segment of LARGE INTESTINE between the CECUM and the TRANSVERSE COLON. It passes cephalad from the cecum to the caudal surface of the right lobe of the LIVER where it bends sharply to the left, forming the right colic flexure.Colon, Transverse: The segment of LARGE INTESTINE between ASCENDING COLON and DESCENDING COLON. It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon.HT29 Cells: Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS.Azoxymethane: A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.Diverticulum, Colon: A pouch or sac opening from the COLON.Intestinal Mucosa: Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.Colonic Diseases: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.Cell Line, Tumor: A cell line derived from cultured tumor cells.Dimethylhydrazines: Hydrazines substituted with two methyl groups in any position.Colectomy: Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)Colonoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the colon.Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Adenoma: A benign epithelial tumor with a glandular organization.Caco-2 Cells: Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.Sigmoid Neoplasms: Tumors or cancer of the SIGMOID COLON.Rectal Neoplasms: Tumors or cancer of the RECTUM.Carcinogens: Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.Gastrointestinal Motility: The motor activity of the GASTROINTESTINAL TRACT.Rectum: The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Cecum: The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.Dextran Sulfate: Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Mice, Nude: Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.Precancerous Conditions: Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)Butyrates: Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.Anticarcinogenic Agents: Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Intestinal Polyps: Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.Rats, Inbred F344Colitis, Ulcerative: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.Intestine, Large: A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.beta Catenin: A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Colostomy: The surgical construction of an opening between the colon and the surface of the body.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Genes, APC: Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.Cecal Neoplasms: Tumors or cancer of the CECUM.Aberrant Crypt Foci: Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.Sigmoid Diseases: Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Neoplasm Transplantation: Experimental transplantation of neoplasms in laboratory animals for research purposes.Intestines: The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.Carcinoembryonic Antigen: A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.Enema: A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.Mucins: High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.Ileum: The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.Trinitrobenzenesulfonic Acid: A reagent that is used to neutralize peptide terminal amino groups.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Cathartics: Agents that are used to stimulate evacuation of the bowels.Feces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.Intestine, Small: The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Mice, Inbred BALB CTransplantation, Heterologous: Transplantation between animals of different species.Intestinal Neoplasms: Tumors or cancer of the INTESTINES.Cyclooxygenase 2: An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.Neoplasm Proteins: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Microsatellite Instability: The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.Adenomatous Polyposis Coli Protein: A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Diverticulitis, Colonic: Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Diet: Regular course of eating and drinking adopted by a person or animal.Mice, Inbred C57BLBarium Sulfate: A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Dietary Fiber: The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.Sulindac: A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.Muscle, Smooth: Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Methylhydrazines: Hydrazines substituted by one or more methyl groups in any position.Drug Screening Assays, Antitumor: Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.Neoplasm Invasiveness: Ability of neoplasms to infiltrate and actively destroy surrounding tissue.Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.Adenomatous Polyps: Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)Mucin-2: A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.Intestinal Perforation: Opening or penetration through the wall of the INTESTINES.Esophagoplasty: A plastic operation on the esophagus. (Dorland, 28th ed)Neoplasms, Experimental: Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.Digestive System: A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).Megacolon: Dilatation of the COLON, often to alarming dimensions. There are various types of megacolon including congenital megacolon in HIRSCHSPRUNG DISEASE, idiopathic megacolon in CONSTIPATION, and TOXIC MEGACOLON.Epithelial Cells: Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Anti-Inflammatory Agents, Non-Steroidal: Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Myenteric Plexus: One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)DNA, Neoplasm: DNA present in neoplastic tissue.Xenograft Model Antitumor Assays: In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.Down-Regulation: A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Liver Neoplasms: Tumors or cancer of the LIVER.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Intestinal Absorption: Uptake of substances through the lining of the INTESTINES.Prostaglandin-Endoperoxide Synthases: Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Antigens, Neoplasm: Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.Sigmoidoscopy: Endoscopic examination, therapy or surgery of the sigmoid flexure.Gastrointestinal Contents: The contents included in all or any segment of the GASTROINTESTINAL TRACT.Immunoenzyme Techniques: Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Up-Regulation: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Fatty Acids, Volatile: Short-chain fatty acids of up to six carbon atoms in length. They are the major end products of microbial fermentation in the ruminant digestive tract and have also been implicated in the causation of neurological diseases in humans.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Deoxycholic Acid: A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.DNA Methylation: Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.Colitis, Ischemic: Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.Gastrointestinal Tract: Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Jejunum: The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Levamisole: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Antimetabolites, Antineoplastic: Antimetabolites that are useful in cancer chemotherapy.Isoenzymes: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.Chemotherapy, Adjuvant: Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Camptothecin: An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.Genes, ras: Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.Defecation: The normal process of elimination of fecal material from the RECTUM.Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.Colonoscopes: Specially designed endoscopes for visualizing the interior surface of the colon.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.RNA, Neoplasm: RNA present in neoplastic tissue.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Organoplatinum Compounds: Organic compounds which contain platinum as an integral part of the molecule.Adenoma, Villous: An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)Piroxicam: A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Leucovorin: The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Chlorides: Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Peristalsis: A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.Colonography, Computed Tomographic: A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.Antineoplastic Agents, Phytogenic: Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.Drug Synergism: The action of a drug in promoting or enhancing the effectiveness of another drug.Stomach: An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.Ileostomy: Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.Senna Extract: Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.DNA Mismatch Repair: A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.Cyclooxygenase 2 Inhibitors: A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.Thymidylate Synthase: An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.Intestinal Polyposis: The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).Curcumin: A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.Dinoprostone: The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Submucous Plexus: One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)Microsatellite Repeats: A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).Sialomucins: A subcategory of mucins that contain SIALIC ACID.Gastrointestinal Neoplasms: Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.Cytoskeletal Proteins: Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.Cyclooxygenase Inhibitors: Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.Diverticulosis, Colonic: A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.Bifidobacterium: A rod-shaped, gram-positive, non-acid-fast, non-spore-forming, non-motile bacterium that is a genus of the family Bifidobacteriaceae, order Bifidobacteriales, class ACTINOBACTERIA. It inhabits the intestines and feces of humans as well as the human vagina.Mice, SCID: Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.TCF Transcription Factors: A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.Wnt Proteins: Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.Adenocarcinoma, Mucinous: An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)Proto-Oncogene Proteins: Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.Antigens, Tumor-Associated, Carbohydrate: Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Cocarcinogenesis: The combination of two or more different factors in the production of cancer.Drug Resistance, Neoplasm: Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.Lung Neoplasms: Tumors or cancer of the LUNG.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

A smooth muscle tone-dependent stretch-activated migrating motor pattern in isolated guinea-pig distal colon. (1/35)

We have investigated the tone dependence of the intrinsic nervous activity generated by localized wall distension in isolated segments of guinea-pig distal colon using mechanical recordings and video imaging of wall movements. A segment of colon was threaded through two partitions, which divided the colon for pharmacological purposes into oral, stimulation and anal regions. An intraluminal balloon was located in the stimulation region between the two partitions (12 mm apart). Maintained colonic distension by an intraluminal balloon or an artificial faecal pellet held at a fixed location generated rhythmic (frequency 0.3 contractions min(-1); duration approximately 60 s) peristaltic waves of contraction. Video imaging of colonic wall movements or the selective application of pharmacological agents suggested that peristaltic waves originated just oral (< or = 4 mm) to the pellet and propagated both orally (approximately 11 mm s(-1)) and anally (approximately 1 mm s(-1)). Also, during a peristaltic wave the colon appears to passively shorten in front of a pellet, as a result of an active contraction of the longitudinal muscle oral to the pellet. Faecal pellet movement only occurred when a rhythmic peristaltic wave was generated. Rhythmic peristaltic waves were abolished in all regions by the smooth muscle relaxants isoproterenol (1 microM), nicardipine (1 microM) or papavarine (10 microM), and by the neural antagonists tetrodotoxin (TTX; 0.6 microM), hexamethonium (100 microM) or atropine (1 microM), when added selectively to the stimulation region. Nicardipine, atropine, TTX, or hexamethonium (100 microM) also blocked the evoked peristaltic waves when selectively added to the oral region. Nomega-nitro-L-arginine (L-NA; 100 microM) added to the anal region reduced the anal relaxation but increased the anal contraction, leading to an increase in the apparent conduction velocity of each peristaltic wave. In conclusion, maintained distension by a fixed artificial pellet generates propulsive, rhythmic peristaltic waves, whose enteric neural activity is critically dependent upon smooth muscle tone. These peristaltic waves usually originate just oral to the pellet, and their apparent conduction velocity is generated by activation of descending inhibitory nerve pathways.  (+info)

Distinguishing right from left colon by the pattern of gene expression. (2/35)

Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis. These differences may reflect distinct biological characteristics of proximal and distal colonic mucosa, acquired in embryonic or postnatal development, that determine a differential response to uniformly distributed environmental factors. Alternatively, the differences in the epidemiology of proximal and distal CRCs could result from the presence of different procarcinogenic factors in the ascending versus descending colon, acting on cells with either similar or distinct biological characteristics. We applied cDNA microarray technology to explore the possibility that mucosal epithelium from adult proximal and distal colon can be distinguished by their pattern of gene expression. In addition, gene expression was studied in fetal (17-24 weeks gestation) proximal and distal colon. More than 1000 genes were expressed differentially in adult ascending versus descending colon, with 165 genes showing >2-fold and 49 genes showing >3-fold differences in expression. With almost complete concordance, biopsies of adult colonic epithelium can be correctly classified as proximal or distal by gene expression profile. Only 87 genes were expressed differently in ascending and descending fetal colon, indicating that, although anatomically relevant differences are already established in embryonic colon, additional changes in gene expression occur in postnatal development.  (+info)

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/35)

1. Mechanisms involved in Ca(2+) sensitization of contractile elements induced by the activation of muscarinic receptors in membrane-permeabilized preparations of the rat proximal and distal colon were studied. 2. In alpha-toxin-permeabilized preparations from the rat proximal and distal colon, Ca(2+) induced a rapid phasic and subsequent tonic component. After Ca(2+)-induced contraction reached a plateau, guanosine 5'-triphosphate (GTP) and carbachol (CCh) in the presence of GTP further contracted preparations of both the proximal and distal colon (Ca(2+) sensitization). Y-27632, a rho-kinase inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization more significantly in the proximal colon than in the distal colon. 3. Y-27632 at 10 microm had no effect on Ca(2+)-induced contraction or slightly inhibited phorbol-12,13-dibutyrate-induced Ca(2+) sensitization in either proximal or distal colon. Chelerythrine, a protein kinase C inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization in the distal colon, but not in the proximal colon. The component of Ca(2+) sensitization that persisted after the chelerythrine treatment was completely inhibited by Y-27632. 4. In beta-escin-permeabilized preparations of the proximal colon, C3 exoenzyme completely inhibited GTP plus CCh-induced Ca(2+) sensitization, but PKC(19-31) did not. In the distal colon, C3 exoenzyme abolished GTP-induced Ca(2+) sensitization. It inhibited CCh-induced sensitization by 50 % and the remaining component was inhibited by PKC(19-31). 5. These results suggest that both protein kinase C and rho pathways in parallel mediate the Ca(2+) sensitization coupled to activation of muscarinic receptors in the rat distal colon, whereas the rho pathway alone mediates this action in the proximal colon.  (+info)

Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/35)

BACKGROUND: Because of their suggested link with microsatellite instability high colorectal cancers, right sided hyperplastic polyps (HPs) may differ from their distally located counterparts. This is highlighted by the recognition of a variant HP, termed sessile serrated adenoma (SSA), which predominates in the proximal colon. HPs displaying the morphological features now associated with SSAs have been shown to have altered expression of "cancer associated" markers, but no studies have investigated whether this is dependent on anatomical location of the polyps. AIMS: To evaluate morphological and functional features in right versus left sided HPs from patients without colorectal cancer with the aim of identifying distinguishing characteristics. METHODS: HPs originating in the proximal and distal colorectum were histochemically and immunohistochemically stained to evaluate a panel of markers related to proliferation and differentiation. In addition, a series of morphological features was evaluated for each polyp. RESULTS: Crypt serration, crypt dilatation, and horizontal crypt growth were more common among HPs from the right side, whereas histochemical factors including mucin changes, global methylation status, and expression of carcinoembryonic antigen were not significantly different. An age disparity was also seen between patients with right versus left sided lesions, with patients with right sided lesions being an average of more than 10 years younger than those with left sided lesions. CONCLUSIONS: These findings suggest that right and left sided HPs differ mainly in terms of growth regulation rather than cellular differentiation, implying that these lesions belong to a continuous spectrum of serrated polyps that differ quantitatively rather than qualitatively.  (+info)

Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy. (5/35)

AIM: To review the risk of proximal colon cancer in patients undergoing colonoscopy. METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination). Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma). The sites of neoplasms were defined as rectosigmoid (rectum and sigmoid colon) and proximal colon (from cecum to descending colon). RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings. Among the 157 patients with proximal colon cancer, 74% had no neoplasm in the rectosigmoid colon. Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer. CONCLUSION: Sigmoidoscopy is inadequate for colorectal cancer screening, especially in older populations.  (+info)

Withdrawing method of the stiffening tube incidentally inserted into the descending colon. (6/35)

We experienced a very rare complication of colonoscopy, a migration of stiffening tube into the colorectum. We herein introduce a withdrawing method of migrating stiffening tube incidentally inserted into the colorectum. A 65-year-old Japanese woman underwent colonoscopy because of abdominal discomfort. We used stiffening tube to insert the scope to the proximal colon because of her redundant sigmoid colon. When withdrawing the scope, we realized that the tube was fully inside the colorectum. We could not remove the tube instantly, and it reached the splenic flexure, finally. We reinserted the scope through the migrating tube, straightened the scope, and withdrew it holding a slight angle of the scope over the proximal end of the tube. Then, we could safely remove the tube along with the scope through the anus.  (+info)

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (7/35)

BACKGROUND: Despite the fact that the alimentary tract is part of the body's first line of defense against orally ingested xenobiotica, little is known about the distribution and expression of cytochrome P450 (CYP) enzymes in human colon. Therefore, expression and protein levels of four representative CYPs (CYP2C(8), CYP2E1, CYP3A4, and CYP3A5) were determined in human colon mucosa biopsies obtained from ascending, descending and sigmoid colon. METHODS: Expression of CYP2C, CYP2E1, CYP3A4, and CYP3A5 mRNA in colon mucosa was determined by RT-PCR. Protein concentration of CYPs was determined using Western blot methods. RESULTS: Extensive interindividual variability was found for the expression of most of the genes. However, expression of CYP2C mRNA levels were significantly higher in the ascending colon than in the sigmoid colon. In contrast, mRNA levels of CYP2E1 and CYP3A5 were significantly lower in the ascending colon in comparison to the descending and sigmoid colon. In sigmoid colon protein levels of CYP2C8 were significantly higher by ~73% than in the descending colon. In contrast, protein concentration of CYP2E1 was significantly lower by ~81% in the sigmoid colon in comparison to the descending colon. CONCLUSION: The current data suggest that the expression of CYP2C, CYP2E1, and CYP3A5 varies in different parts of the colon.  (+info)

Comparative study of descendent colon rupture resistance considering traction force of rupture and total energy of rupture in rats. (8/35)

PURPOSE: To compare total energy of rupture and traction force of rupture tests within a rupture resistance study of descendent colon of rats. METHODS: Twelve descendent colon segments of rats were considered to perform the study. For each one of the specimens, total energy of rupture and traction force of rupture necessary to promote colic wall burst were evaluated through the biomechanical total energy of rupture test using the Biomechanical Data Acquisition and Analysis System, version 2.0. Average, standard deviation, standard error of average and coefficient of variation were considered for analysis of results. RESULTS: Traction force of rupture average, standard deviation, standard error of average and coefficient of variation were 380.05 gf, 98.74, 28.5 e 25.98%, respectively while total energy of rupture presented average of 244.85 gf, standard deviation of 57.76, standard error of average of 16.67 and coefficient of variation of 23.59. CONCLUSION: Although, total energy of rupture considered a larger number of attributes to its calculation related to non-linear viscoelastic materials, such as colic wall, it presented a smaller coefficient of variation when compared to traction force of rupture, thus demonstrating to constitute a possible parameter to analyze intestinal resistance of rats.  (+info)

An EVAR often requires multiple wires and catheters be transferred into the vessel via an introducer sheath, which can lead to blood loss through the sheath valve. The sheaths exclusive DrySeal valve is designed to minimise blood loss, enabling the introduction of multiple devices with haemostasis control.. "Nearly a third of patients being considered for EVAR have an aneurysm that extends to the iliac artery. The Excluder device is a trusted solution in such cases, but previously no introducer sheaths designed for use with this device existed," said Marcus Brooks, consultant vascular surgeon, North Bristol NHS Trust, UK. "With the Gore DrySeal Flex introducer sheath, I now have a sheath specifically designed for use with the iliac branch endoprosthesis and flexible enough for easy access to the iliac branch vessels.". The new sheath leverages technology from Gores DrySeal Sheath, which features a hydrophilic coating for improved access into vessels. In addition, the DrySeal sheath offers an ...
Buy AD-Ducer Femoral Introducer Sheath for angiographic procedures online at best prices. 4/5/6/7/8/9/10 French Size, 11 cm Length, Femoral Introducer Sheath, Includes Introducer Needle. COD Available
The present embodiments provide an introducer sheath having a braided member and methods of manufacture. The introducer sheath comprises an inner tube, a braided member disposed over at least a portion of the inner tube, and an outer tube disposed over the inner tube and the braided member. In one embodiment, the braided member comprises a plurality of intersecting first and second wire segments at least partially covered with a coating. At least a portion of the first and second wire segments are bonded together at one or more intersections, for example, by melting the coating, to reduce movement of at least one of the first and second wire segments with respect to one another. Optionally, a coiled member having a plurality of turns may be disposed over a portion of the braided member and the inner tube.
An introducer sheath (10) is provided for percutaneous insertion of catheters into a blood vessel. The introduction of the sheath (10) through a wall of blood vessel causes an opening to be formed thr
INTRODUCTION: There are several alternatives for one-stage emergency treatment of obstructive left-sided colonic cancer (OLCC): subtotal colectomy, intraoperative colon lavage (IOCL) with primary anastomosis, and the placement of a stent as a temporary measure prior to scheduled surgery. At present, it is not clear whether emergency perioperative lavage or the placement of a stent is the better technique. The hypothesis is that IOCL and primary anastomosis is equal safe or even safer than placement of a stent as a temporary measure prior to scheduled surgery, less length of stay and less cost.. OBJECTIVE: To establish which of these two techniques is more efficient in OLCC from the point of view of morbimortality, economic cost, and long-term survival.. MATERIAL AND METHODS:. Prospective, controlled, randomized study of patients diagnosed with OLCC. Patients were divided into two groups: group 1: stent and deferred surgery; group 2: emergency IOCL. A simple randomization system was used. The ...
A method of indicating divergent product benefits by formulating a hand dishwashing liquid having a cleaning agent and a hand care agent; choosing a sensory element profile comprising one or more soft colors and a pearlescent appearance; and incorporating the sensory element profile into the hand dishwashing liquid, such that the sensory element profile indicates the efficacy of the cleaning agent and the efficacy of the hand care agent.
A prospective, randomized, controlled multi-center clinical trial designed to evaluate the safety and effectiveness of the study device in sealing multiple femoral venous access sites and providing reduced times to ambulation compared with manual compression at the completion of catheter-based procedures performed through 6 - 12 Fr introducer sheaths.. Only patients with multiple access sites will be enrolled in order to support the desired indication. Randomization will be stratified to account for patients with varying numbers of access sites in a 1:1 treatment device to control arm ratio to ensure treatment and control arms have the same proportion of access sites/patient, i.e. 3 access sites/patient vs. 4 access sites/patient. ...
A method for hemostasis of an artery having a puncture after arterial catheterization, the catheterization using an introducer sheath, the method including the steps of inserting a catheter with a first balloon into the introducer sheath, positioning the first balloon against an outside surface of a wall of the artery at the puncture, inflating the first balloon against the outside surface of the artery at the puncture, and maintaining the first balloon against the puncture so that the first balloon substantially seals blood flow from the puncture so as to achieve hemostasis.
To define the characteristics of colorectal cancer with regard to site distribution, age, and sex, due to the significantly increased incidence of colorectal cancer in Japan, we investigated 1,205 Japanese patients with colorectal cancer between 1975 and 1994. When we compared site distribution for age and sex in the entire 20-year period,...
A holding device and method of use with a peelable or otherwise splittable introducer sheath or catheter through which a cardiac pacing lead or other elongated flexible instrument extends into the body of a living being. The introducer is arranged to be grasped by a user to pull the introducer in the proximal direction so that can be withdrawn out of the beings body. The holding device comprises a first or
A vascular clip includes a peripheral body defining a plane, and tines extending from the body transversely with respect to the plane, the tines biased towards a planar configuration. The clip includes expandable elements disposed along its periphery that are biased to expand from compressed to expanded states for increasing a diameter of the clip upon deployment. The clip is provided within a housing slidably mounted on an introducer sheath. The sheath is introduced through a puncture into a blood vessel, and after a procedure is performed via the sheath, the housing is advanced into the puncture and the clip deployed until the tines engage tissue adjacent the opening in the vessel wall. The sheath is withdrawn from the patient, leaving the clip in place. The tines at least partially move towards the planar configuration to pull the engaged tissue together and close the opening.
Generally cardiac. Cancers are very rare and the possibility of being benign is present ..but after the biopsy will be taken..even if it is cancerous and its growth rate is not high..it can be treated with targeted radiotherapy and chemotherapy …The doctor will use a local anesthetic to numb the area of your neck. A plastic introducer sheath (a short, hollow tube through which the catheter is placed) is inserted through a small incision and into a blood vessel in the neck. A bioptome is inserted through the sheath and threaded to the right ventricle. X-rays, called fluoroscopy, are used… Read more » ...
Lizzie Rutherford Coleman, born 8 Mar 1858, died 20 Apr 1934, bur. 21 Apr 1934 - Descendents of John (Jno the Weaver) McBurney 1811-1872
0059] Although conventional wisdom until now has been to reduce the perceived frictional forces, it has been unexpectedly found that the inner housing and the outer housing of embodiments according to the present invention allow the strain that is induced by the displacement of parts of the soft inner seal elements is allowed to fully recover and maintain hemostasis because of the seal element surrounding stiff outer housing. The strain recovery provided by the interaction between the inner and outer housings reduces the extent to which the operator of the introducer sheath feels an increased amount of frictional resistance that is generated between the seals and the implement or device. In other words, it has unexpectedly been found that embodiments according to the present invention provide an acceptable frictional resistance feel when using a wide range of diameters of implements and devices while still providing complete hemostasis across the entire range of diameters. In addition, it has ...
China Balloon Inflation Device supplier, Disposable Pressure Transducer, Introducer Sheath Manufacturers/ Suppliers - Yilson Medical Technology Co., Ltd.
An 810 nm laser with a minimum of 15 W output power is used. Alternatively, a 980 nm laser can be used also with 15 W minimum output power. A 600 micron optical fibre is needed together with a guide wire introducer sheath and needle for percutaneous perforation.. Prior to treatment the SFJ and GSV are mapped through use of colour duplex ultrasound.. The guide wire introducer sheath is introduced into the GSV - at level with the knee or the lower part of the thigh. The fibre is advanced via the introducer sheath until the fibre tip is positioned 1-2 cm distal to the SFJ. A red guiding light emitted from the fibre tip provides a helpful indication of the tip position. Prior to release of the laser beam, the exact tip position is controlled carefully by use of ultrasound.. When laser is delivered by the introduced fibre, heating of the blood leads to formation of a steam bubble. That is, the effect of the laser is not achieved through contact with the wall of the blood vessel, but rather by ...
A colon lipoma is a remarkably rare tumor. In most cases, the tumors are asymptomatic and small in size, need to be differentiated from malignant tumors, and do not need any special treatment. Selection of the right surgical strategy depends on the status of bowel, as well as the size and the location of tumor. We encountered two patients with giant submucosal lipomas that had induced intussusceptions: one with a lipoma in the transverse colon and the other with a lipoma in the ascending colon. The diagnoses were made by using histological examinations ...
[Stenosing ganglioneuromatosis of the small intestine with ileus and ileal rupture].: Report on a 64-year-old man who presented with ileus and rupture of the il
NOTE: This product contains Di(2-ehylhexyl) phthalate (DEHP). Togo Medikit has conducted a Chemical Safety Assessment of DEHP in this device based on currently known acceptable exposure limits for sensitive populations (children and pregnant/nursing women), and has determined that the potential exposure is below the known acceptable exposure limits for the device when used in accordance with the indications and instructions for use.. ...
Effect of Anatomical Distribution of Mast Cells on Their Defense Function against Bacterial Infections: Demonstration Using Partially Mast Cell deficient tg/tg ...
Shows off the glittering wings of Dee Dee the Dragonfly Ocean Theme Wall Decor. Create a fun scene in a childrens waiting area, library, or lobby. Designed to give children pieces to touch, feel, see and explore with their senses! Made from solid birch smooth wood, stunning gentle colors, and hidden sensory elements to help make a child smile and learn. Size: 11 3/4W x 11 3/4H. Mounting hardware included. Item054156 Made by HABA Play Wall Decor
Has anyone heard or experimented with float tanks as an intervention? Ive heard it can be beneficial, and it seems to make sense. REST or restrictive environmental stimulus therapy indicates that it could be beneficial for individuals who struggle with sensory elements by lowering the frequency of brain waves, increasing neurochemicals for joy and decreasing stress hormones. In addition, the solution of magnesium sulfate can be beneficial by cleansing and detoxifying. Just wondering if anyone has tried this ...
A catheter is disclosed which is capable of cutting obstructive tissue from a vessel of a living body while shielding a portion of the wall of the vessel from being exposed to the cutting blade at the catheters distal end. An essentially continuous outer surface at the catheters distal end allows it to be readily advanced through an introducer sheath and through a tight stenosis in an artery. The shield at the catheters distal end could subtend an arc from as little as 45 degrees to as large as 270 degrees depending on the extent of the vessel wall that is to be protected from being cut. A vacuum source at the catheters proximal end can cause a suction to exist at a cutout at the catheters distal end in order to pull obstructive tissue into the cutout as the cutting cylinder is pulled back in a retrograde direction, this suction being capable of enhancing the removal of the obstructive tissue.
A splittable medical valve is disclosed that is configured with a interfacing region that permits the valve to be placed over or inside of a tubular medical device, such as a splittable introducer sheath, to prevent loss of bodily fluids and/or reduce ingress of air-borne pathogens. The valve further includes a sealing element configured to accept passage of a medical device, such as a catheter, sheath, pacemaker lead, or other ancillary device therethrough, whereby the valve body is split along one or more lines or fissure to allow removal of the valve from around the ancillary device.
SMB: Buy complete range of Cath-Lab products online|PTCA Balloons, Coronary Diagnostic Catheter, Guidewire, Femoral Introducer Sheath, Radial Sheath|Lowest Prices|COD Available
[173 Pages Report] Interventional Cardiology Devices Market categories the Global market by type (Angioplasty, Catheters, Plaque Modification (Atherectomy, Thrombectomy), Hemodynamic Flow Alteration (Embolic Protection, Total Occlusion), Guidewire, Introducer Sheath)) & Geography
This channel includes news, techniques and new technology innovations for radial access, also called transradial access or radial artery access. This concerns the location of introducer sheaths and vascular access for interventional procedures. Radial access is supported to result in fewer complications compared to femoral access.
Mic Introducer Kit indeholder 4 stk. SAF-T-PEXY® T-låse, Pean introducernål, guidewire, skalpel, dilatator, sprøjte, målepind. Mic-Key TJ Introducer Kit indeholder også et seeking catheter. Læs mere på mic-key.dk. ...
Descendents - Eunuch Boy Lyrics. Descendents Everything Sucks Eunuch Boy Eunuch boy, eunuch boy Thought a lawnmover was another toy Dont laugh at him cause he cant piss
RelA/p65 is a main subunit of nuclear factor-kappaB (NF-kappaB) that regulates expression of genes involved in cell growth and survival, stress response, and inflammation, but its oncogenic or tumor-suppressive function in tumorigenesis has been highly controversial. Hundreds of NF-kappaB inhibitors have been developed for targeted cancer therapy, but fail to achieve anticipated anticancer efficacy. Complexity of posttranslational modifications may contribute to tumorigenic diversity of RelA/p65, but mechanisms of action remain unclear. Here we show that phosphorylation of RelA/p65 at Ser536 functions as a tumor suppressor. In normal human colon mucosa, RelA/p65 phosphorylation at Ser536 is gradually increased with the maturation and apoptotic shedding of cryptic cells, but the phosphorylation is significantly decreased in colon tumors. In RelA/p65-silenced breast and colon cancer cells, reconstitution of a constitutively active RelA/p65, whose Ser536 was replaced by aspartic acid (named p65/S536D),
Method and apparatus for providing an introducer for transcutaneous placement of at least a portion of an analyte sensor through the skin of a patient is provided.
Colon cleansing is the process of taking poison from your body. These general tips will help you in your first colon cleansing experience.
Brilliant sunny day punk-pop for fans of The Ramones, Mr T Experience and The Descendents. With a Leonard Cohen cover on the flip.
Looking to meet the right Spiritual Singles in Colon? See your matches for FREE on eHarmony - #1 trusted Colon, NE online dating site.
Cumpara rapid si simplu Colon Curat. Colon Curat are rolul de a elimina toate toxinele acumulate din colon si de a stimula functia de drenare.
Colon 365 Cleanse is their sole product and its only sold on their website, The ingredients that are included in Colon 365 Cleanse will be familiar to anyone
For proper care of colon health, its a good idea to look into all of the various facets of colon function first, to gain a better understanding.
Colon cleansing can be safe and has positive impact toward our health. Find out more about natural colon cleanse and oxygen colon cleanse as the best alternatives. 09/17/2008 ...
OK, a single colon follows an access specifier, such as public: or private: or protected:, right? Are there any other situations in which a single col
The best colon cleanses come from the best products. To find the best products, you need to know how to look for the right company.
Periods, colons, and semicolons all have the ability to stop a sentence in its tracks, but for very different purposes. In this lesson, learn how...
Our bodies are created to detoxify and cleanse themselves, but there is a limit for everyone. How to cleanse your colon when you reach this toxic threshold?
The colon is a mark of punctuation (:) used after a statement that introduces a quotation, an explanation, an example, or a series.
BACKGROUND: Transradial percutaneous coronary intervention (PCI) offers important advantages over transfemoral PCI, including better outcomes. However, when there is indication to ad hoc PCI, a 6 French workflow is a common default strategy, hence potentially influencing vascular access selection in patients with anticipated small size radial artery. METHODS: A multidimensional evaluation was performed to compare two ad hoc interventional strategies in women ,160cm: a full 6 French workflow (namely 6 French introducer sheath, diagnostic catheters and guiding catheter) with a modified workflow consisting in the use of 5 French diagnostic catheters preceded by the placement of a 6 French sheath introducer and followed by a 6 French guiding catheter use for PCI ...
article{3c1d0d1b-0530-4d68-8c34-76c362110061, abstract = {,p,The involvement of cytosolic phospholipase A,sub,2,/sub, (cPLA,sub,2,/sub,) in apoptosis of adult mouse superior cervical and dorsal root ganglia neurons has been investigated by the use of immunohistochemistry for cPLA,sub,2,/sub, and DNA nick-end labeling for apoptotic cells, respectively, cPLA,sub,2,/sub, immunoreactivity was strongly upregulated in neurons of both preparations during in vitro culturing. By double labeling it was unequivocally demonstrated that cPLA,sub,2,/sub, was present and upregulated only in neurons undergoing apoptosis. A similar picture emerged when cPLA,sub,2,/sub, immunoreactivity was compared with staining with Fluoro-Jade, a novel fluorochrome marker for neuronal degeneration. The preferential presence of cPLA,sub,2,/sub, in apoptotic and degenerating cells suggests that the enzyme is important for some mechanism involved in or intimately coupled to neuronal cell death.,/p,}, author = {Hornfelt, M. and ...
Post written by Alberto Arezzo, MD, from the Department of Surgical Sciences, University of Torino, Turin, Italy. Twenty years after the first description of the technique, the debate is still open on the role of self-expandable metallic stent (SEMS) placement as a bridge to elective surgery for symptomatic left-sided malignant colonic obstruction. The focus of…
The BD Introsyte-N Autoguard shielded introducer for PICC and midline catheters is a 0.56-in introducer that includes all the features of the BD Introsyte|sup|™|/sup| Autoguard|sup|™|/sup| shielded introducer.
Blood samples (5 mL) were drawn from the PV and tumor DV and placed in plain tubes. PV blood was obtained 1 hour prior to surgical incision. DV blood was obtained prior to the ligation of any branch of the SMV in patients with proximal colon cancer and prior to ligation of the IMV in patients with distal colon cancers. Samples were immediately centrifuged, and plasma and serum were separately stored at −70°C until analysis. enzyme-linked immunosorbent assay (ELISA) was performed using commercially available kits (IBL-Hamburg GmbH, Hamburg, Germany) according to manufacturers instructions. Diluted serum was transferred to wells of plates pre-coated with primary antibody. Following the recommended incubation period, plates were washed with buffer solution, and substrate solution was added and incubated as instructed. The wells were developed with a color-reagent. Stop solution was added to each well after incubation and the optical density was measured at a wavelength of 450 nm using automated ...
Peel Away Sheath Introducer ISOMed Peel Away Introducers allow for smooth catheter insertion and manipulation. The X.R.O. peel away sheath allows the device to be completely removed without shifting the catheter out of position.The
Formerly it was thought by a few Hygienists that it was necessary to eat the least concentrated food first and the most concentrated food last. The reason for this was that the foods were supposedly layered in the stomach, and it was thought best not to mix them; to permit the juicier foods to be evacuated from the stomach first. It has been shown, however, that food does not stay in layers in the stomach, and the pyloric valve does not open with each peristaltic wave so that food will become mixed in the stomach even if you eat the most concentrated food last. For instance, let us say that you eat some subacid fruit first. The pyloric valve stays tightly shut for fifteen minutes after the beginning of a meal, then it begins to open and pass a tiny bit of food to the duodenum. Each time there is a contraction of the stomach, the food is pushed forward toward the pylorus (the lower end of the stomach). As the valve opens only occasionally and not each time the peristaltic wave pushes food toward ...
Medikabazaar is Indias largest B2B marketplace for Medical Devices and Medical Supplies. Buy Sumi Tracheal Tube Introducer For Infants1.6 mm 09-1610 at best price and get doorstep delivery. Shop now and get best deals on all products.
Homemade remedies for colon cleansing - Why You Should Consider Homemade Colon Cleansing | Colon.... Bowtrol Colon Cleanser Health Support forumlas include natural colon cleanse supplements and natural Sensitive Digestion remedies.
How to jump start your colon after surgery - Journey to the Center of Your Colon - Understanding Leaky Gut.... Bowtrol Colon Cleanser Health Support forumlas include natural colon cleanse supplements and natural Sensitive Digestion remedies.
Cleansing Colon 4.26 Cleansing Colon Advanced Calculator to Check Your Colon if Need Cleansing Based on Body Equations and Help you To Properly Lose Weight Naturally using Special Diets and Colon ...
Health & Wellness column: - Many ancient cultures recognized that all disease begins in the colon and they developed different ways to keep the colon healthy. The August Theres a Yogi in the Kitchen column offers Flourishing Flora...The yogis way to a healthy colon. It includes simple ways you can begin to build healthier flora in your colon and a variety of homemade yogurt recipes.
Colon cleansing in a short time is done by performing an enema, in which fluid is introduced into the colon with a special tool and is used to clear out the colon of solid mass. Avoiding solid food...
Map of Colon area hotels: Locate Colon hotels on a map based on popularity, price, or availability, and see TripAdvisor reviews, photos, and deals.
Can a colon cleanse clear up acne? Unless you somehow managed to get acne in your colon, the answer is no, but colon health actually is important to your
Keep your body and health in check with a visit to Colon Rectal Surgical Associates in Glen Burnie. Colon Rectal Surgical Associates provides exceptional and gentle medical treatments, such as physicals.If you have come down with a cold or flu, the doctors at Colon Rectal Surgical Associates are ready to assist you.
Find 13 listings related to Colon And Rectal in Deltona on YP.com. See reviews, photos, directions, phone numbers and more for Colon And Rectal locations in Deltona, FL.
Super CKL Colon Detox(60 Capsules) All Natural Herbal Colon Cleanser. Designed to improve digestion and help remove the buildup of waste in the intestinal tract and maintain regularity and detoxify the Kidney, Liver & Spleen.*
Your account has been temporarily locked Your account has been temporarily locked due to incorrect sign in attempts and will be automatically unlocked in 30 mins. For immediate assistance, contact Customer Service: 800-638-3030 (within USA), 301-223-2300 (international) [email protected] ...
Colon cancer (colorectal cancer) support forum. Please feel free to read, share your thoughts, your stories and connect with others!
Colon cancer (colorectal cancer) support forum. Please feel free to read, share your thoughts, your stories and connect with others!
Cancerlacolon.ro isi propune sa vina in ajutorul celor care isi doresc sa previna cancerul de colon dar si in ajutorul celor care sufera de acesta. Profilaxie, simptome, teste si tratamente pentru can
Looking for a model? Check the model profile of Olivia Colon from United States. See other portfolios and book models on modelmanagement.com
Question - I have been diagnosed with sigmond colon and AAA wich - 8E. Find the answer to this and other Medical questions on JustAnswer
Exact repro reissue of this late 60s recording from a 20-year old Willie Colon, following in the Fania labels tradition of amazing Latin soul. ...
The largest case series of ganglioneuromatosis was reported by Shekitka et al.3 in 1994 where 43 patients with intestinal ganglioneuromatous disease were followed. While some patients presented with abdominal pain, rectal bleeding or megacolon, many were asymptomatic. However, cases with watery diarrhea secondary to vasoactive intestinal polypeptide secretion and diffuse ganglioneuromatosis involving the colon and rectum have been reported,8,9 as well as upper GI bleeding from a ganglioneuroma of the duodenum10 and polypoid GN causing colonic intussusception.11 The prevalence of diffuse ganglioneuromatosis in patients with MEN-IIB syndrome is nearly 100%, and often gastrointestinal involvement predates the development of medullary thyroid cancer.1 Diarrhea or constipation from diffuse alimentary tract involvement, was reported in a case series of 16 patients with MEN-IIB.1 DG was found before medullary thyroid carcinoma in 12 of these16 cases. Therefore, the authors concluded that diffuse ...
Elevated total dietary fiber intake was associated with a reduced risk of incident distal colorectal adenoma (OR highest v. lowest tertile of intake 0.76, 95%CI: 0.63-0.91, Ptrend=0.003), but not recurrent adenoma (Ptrend =0.67). Although the association was not statistically significant for colorectal cancer overall (HR 0.85, 95%CI: 0.70-1.03, Ptrend=0.10), a reduced risk of distal colon cancer was observed with increased total fiber intake (HR 0.62, 95%CI: 0.41-0.94, Ptrend=0.03). Protective associations were most notable for fiber originating from cereals or fruit.. ...
This constructive nature of visual perception has only recently been fully appreciated. Earlier thinking about sensory perception was greatly influenced by the British empiricism philosophers, notably John Locke, David Hume, and George Berkeley, who thought of perception as an atomistic process in which simple sensory elements, such as color, shape, and brightness, were assembled in an additive way, component by component. The modern view that perception is an active and creative process that involves more than just the information provided by the retina has its roots in the philosophy of Immanuel Kent and was developed in detail in the early 20th century by the German psychologists Max Wertheimer, Kurt Koffka, and Wolfgang Koehler, who founded the school of Gestalt psychology ...
Continued From Above... The descending colon is a hollow tube that is part of the gastrointestinal (GI) tract. Its diameter is roughly 2.5 inches (7 cm), while its length is approximately 9 to 10 inches (25 cm). It contains many small pouches, known as haustra, along its length that increase its surface area and help to move feces through the colon. At its superior end, the descending colon connects to the transverse colon at the splenic flexure just inferior to the spleen. From the splenic flexure, the descending colon extends inferiorly toward the left hip before turning about 90 degrees to the right and forming the sigmoid colon.. Like all parts of the gastrointestinal tract, the descending colon consists of four major tissue layers surrounding a hollow lumen. The mucosa forms the innermost layer that surrounds the lumen and is in contact with fecal matter stored in the colon. Mucosa is a mucous membrane made of simple columnar epithelial tissue and a thin underlying layer of areolar ...
The objective of this registry is to compile clinical data on the use of the Evolution® Colonic Stent System for the palliative treatment of colonic ob
... ,Used for placement of .035 inch (0.89 mm) or .038 inch (0.97 mm) diameter wire guides into the vascular system when a small 24 gage needle stick is desired.,medicine,medical supply,medical supplies,medical product
Tytuł projektu: Rozbudowa i przekształcenie bibliograficznej bazy danych AGRO w bazę bibliograficzno-abstraktową z wykorzystaniem oprogramowania YADDA. Nr umowy: POIG 02.03.02-00-031/09 (okres realizacji 2009-2013 ...
Results Two hundred and thirty patients with 255 EMR scars were included. The prevalence of recurrent adenoma was 24%. Diagnostic values were high for all modes (negative predictive value (NPV) ≥97%, positive predictive value (PPV) ≥81%, sensitivity ≥90%, specificity ≥93% and accuracy ≥93%). In high-confidence cases, NBI with NF had NPV of 100% (95% CI 98% to 100%) and sensitivity of 100% (95% CI 93% to 100%). Use of clips at initial EMR increased diagnostic inaccuracy (adjusted OR=1.68(95% CI 1.01 to 2.75)). In offline assessment, specificity was high for all imaging modes (mean: ≥93% (range: 55%-100%)), while sensitivity was significantly higher for NBI-NF (82%(72%-93%)%)) compared with WL (69%(38%-86%); p,0.001), WL-NF (68%(55%-83%); p,0.001) and NBI (71%(59%-90%); p,0.001). ...
Helpful, trusted answers from doctors: Dr. Kaplan on transverse colon symptoms: Consult your doctor about your risks of cancer. Only way to know for sure is to get colonoscopy.
The Prelude Ease hydrophilic sheath is designed specifically for accessing the radial artery with ease. The hydrophilic sheath can reduce arterial spasms.
This site uses cookies to improve your user experience. By using this website, you agree that we can place cookies on your device. For further information, please read our Privacy And Cookies Policy. I accept the terms and conditions ...
Your account has been temporarily locked Your account has been temporarily locked due to incorrect sign in attempts and will be automatically unlocked in 30 mins. For immediate assistance, contact Customer Service: 800-638-3030 (within USA), 301-223-2300 (international) [email protected] ...
Lets focus on the pink node. This node represents a group of organisms, including all descendents of a common ancestor. Nodes can have two or more descendent nodes (representing subgroups of the ancestral node), and one or more ancestral nodes. (The Tree of Life does not currently support nodes with multiple ancestral nodes, but that will be necessary in the future to fully accommodate those portions of the ToL with an anastomosing genetic history.). ...
Colon cleanse products for a healthy colon on sale at Arnold Supplements. Buy all your colon cleansers and colon cleanse products here. The key to a healthy colon is a daily colon cleanse.
Cancer Colon Health: 20 assigned downloads, like HealthScouter Colon Cancer: Colon Cancer Early Symptoms: Colon Cancer Warning Signs: Treatments for Colon Cancer (HealthScouter Colon Cancer) from ebook-reader
In the UK alone the statistics make sombre reading. Did you know that most people can suffer with problems in their colon at some time in their life, those less fortunate suffer long term? Its one of those subjects that no-one wants to openly discuss either and that means you may not get support when you need it and you may not have the information you need to make informed choices. Understanding is part of the key and thats what this website is about. Because your Colon works to eliminate waste from your body it is an integral part of keeping you well and healthy.. The colon works hard on your behalf clearing the toxins that enter your system and trying to evacuate the toxins on a regular basis. Help your colon to help yourself! As your colon acts as the sewage system for your body you can get problems if it gets blocked or overloaded. Think about the effects a blocked or faulty sewer would have on your home.. ...
Colon cancer is the cancer that occurs in the large intestine (colon). Through this article, we will make you aware of the signs and symptoms of colon cancer.
Buy Discount Colon Cleanse (Colon Cleansing) Regular 6 oz powder from Health Plus at VitaSprings. Find more product information on Colon Cleanse Regular Powder and shop online.
On 6-Feb-09, at 11:15 AM, Curt Hagenlocher wrote: , On Fri, Feb 6, 2009 at 6:37 AM, Riobard Zhan ,yaogzhan at gmail.com, , wrote: ,, ,, You are assuming colons improve readability, which I disagree. , , Readability isnt an entirely objective metric. But making colons , optional would mean that youre now looking at two different kinds of , code -- with colons and without. And its extremely hard for me to , imagine that having two different kinds of code would not harm , readability. Not when we dump colons like semicolons. We dont see two different kinds of code, one with semicolons and the other without ...
Buy Discount Super Colon Cleanse (Colon Cleansing) 12 oz powder from Health Plus at VitaSprings. Find more product information on Super Colon Cleansing Powder and shop online.
When beginning a detox, the first organ that needs to be addressed is the colon. The colon is the bodys number 1 elimination channel, and unless it is properly working, detoxifying other organs of the body will be nowhere near as beneficial-and in some cases, can even cause harm. This is because if you are detoxing with a sluggish colon, the toxins we are trying to remove from the body will have no way of exiting. They can then recirculate around the body, causing damage.. A backed-up, sluggish colon can be at the heart of many health problems. With bowel cancer making it into the top 3 most common cancers diagnosed each year in Australia, it is easy to see just how important bowel health is.. When faecal matter is backed up in the colon, it becomes toxic. Doing a colon detox (using my Colon Detox #1 AND Colon Detox #2) can help you to resolve problems that you never even imagined! Cleaning your colon has been known to help:. ...
Cultured dermal, colon and colon cancer associated fibroblasts induce similarly cancer cell elongation and motility and have equivalent gene expression and acti
This page is a Tree of Life Branch Page.. Each ToL branch page provides a synopsis of the characteristics of a group of organisms representing a branch of the Tree of Life. The major distinction between a branch and a leaf of the Tree of Life is that each branch can be further subdivided into descendent branches, that is, subgroups representing distinct genetic lineages.. For a more detailed explanation of the different ToL page types, have a look at the Structure of the Tree of Life page.. close box ...
nachhören] 1. NOVI CVETYA - ticha ljatna wetzscher 2. MINUTEMEN - little man with a gun in his hand 3. THE REACTORS - disposessed 4. ADAM & THE ANTS - cartrouble 1 & 2 5. MISFITS - - last caress 6. DESCENDENTS - surburban home 7. NACH DEM TODE - inverted ‚y 8. PATIFE - […]. ...
Bowtrol colon cleanse - Bowtrol Colon Cleanse | Healthy lifestyle. Bowtrol is formulated to maximize ones elimination without causing loose stools or uncomfortable cramping.
WebMD looks at colon cleansing, from using supplements to having colon irrigation. Are these products necessary or even beneficial, or is it all a hoax? Get the truth about natural colon cleansing here.
A clean and healthy colon means a lot when it comes to living a healthy life and doing a colon cleanse flush or herbal colon cleanser can serve you well.
Blocked colon - My Bowel is Blocked, What Can Be Done ? - HealthBoards. Bowtrol is formulated to maximize ones elimination without causing loose stools or uncomfortable cramping.
According to WebMD, the type of treatment a doctor chooses for treating a twisted colon depends on where the obstruction occurs in the colon, but typically those options include use of a barium...
Bench colon - FAQ:The Lifts - Starting Strength Wiki. Bowtrol is formulated to maximize ones elimination without causing loose stools or uncomfortable cramping.
Inflmmation of the colon - The Relationship between Sugar and Inflammation. Bowtrol is formulated to maximize ones elimination without causing loose stools or uncomfortable cramping.
A colic flexure is a flexure (a bend) in the colon. There are two colic flexures in the transverse colon. The left colic flexure is near the spleen, and is known as the splenic flexure. ...
NATICK, Mass., June 20, 2011 /PRNewswire/ -- Boston Scientific Corporation (NYSE: BSX) today announced the global launch of its Mustang™ PTA Balloon Catheter, a highly deliverable 0.035 inch percutaneous transluminal angioplasty (PTA) catheter designed for a wide range of peripheral angioplasty procedures. The Company plans to launch the product immediately in the U.S., Europe and other international markets.. Boston Scientific developed the Mustang PTA Balloon Catheter to meet physician needs for a low-profile, high-pressure balloon catheter in a wide range of sizes. It is the first to use Boston Scientifics NyBax™ Balloon Material, a proprietary co-extrusion of nylon and Pebax® polymers engineered to provide high-pressure, non-compliant dilatation in a low-profile balloon. The Mustang Balloon Catheter offers excellent rated burst pressure (up to 24 atmospheres) and is the only 7 x 200 mm balloon compatible with a 5 French introducer sheath. Available in 203 sizes, it provides the ...
Joel Leroy, MD FRCS, Federico Costantino, MD, Michele Diana, MD, Jacopo DAgostino, MD, Didier Mutter, MD PhD, James Wu, MD, Jacques Marescaux, MD FRCS FACS. IRCAD-EITS, Department of Digestive and Endocrine Surgery, University Hospital of Strasbourg, France. Introduction: This prospective study aims to evaluate bacterial peritoneal contamination between different techniques of transabdominal or transanal specimen extraction in a consecutive cohort of patients requiring laparoscopic left colostomies.. Methods: During a 6-month period, we consecutively evaluated the presence of peritoneal cavity contamination in laparoscopic left colectomies using two different specimen extraction techniques, the transanal route with opening of the rectal stump or the classic route (transabdominal extraction using a short laparotomy). Systematic intraoperative bacteriological sampling was performed at the end of the procedure. Intraoperative data as well as microbiological and postoperative outcomes were ...
Disease Information. Johnes disease usually enters a herd when healthy but infected animals are introduced to the herd. Herds that are not infected should take precautions against introduction of Johnes disease. Such precautions include keeping a closed herd, or requiring replacement animals come from test negative herds. In 1998, the United States Animal Health Association approved the Voluntary Johnes Disease Herd Status Program for Cattle (VJDHSP). The VJDHSP provides testing guidelines for States to use to identify cattle herds as low risk for Johnes disease infection. With numerous tests over several years, herds progress to higher status levels. The higher the status level, the more likely a herd is not infected with Johnes disease. In April of 2002, USDA-Animal and Plant Health Inspection Services-Veterinary Service incorporated portions of this program into its national program standards: Uniform Program Standards for the Voluntary Bovine Johnes Disease Control Program (VBJDCP). ...
There are two colic flexures, or curvatures in the transverse colon. The one on the right, the right colic flexure is known as the hepatic flexure. The one on the left, the left colic flexure is known as the splenic flexure. The right colic flexure or hepatic flexure (as it is next to the liver) is the sharp bend between the ascending colon and the transverse colon. The hepatic flexure lies in the right upper quadrant of the human abdomen. It receives blood supply from the superior mesenteric artery. The left colic flexure or splenic flexure (as it is close to the spleen) is the sharp bend between the transverse colon and the descending colon. The splenic flexure is a watershed region as it receives dual blood supply from the terminal branches of the superior mesenteric artery and the inferior mesenteric artery, thus making it prone to ischemic damage in cases of low blood pressure because it does not have its own primary source of blood. In the context of ischemia, the splenic flexure is ...
Inhibitory GABAergic interneurons are important for shaping patterns of activity in neocortical networks. We examined the distributions of inhibitory interneuron subtypes in layer II/III of areas V1 and V2 in 18 genera of anthropoid primates including New World monkeys, Old World monkeys, and hominoids (apes and humans). Interneuron subtypes were identified by immunohistochemical staining for calbindin, calretinin, and parvalbumin and densities were quantified using the optical disector method. In both V1 and V2, calbindin-immunoreactive neuron density decreased disproportionately with decreasing total neuronal density. Thus, V1 and V2 of hominoids were occupied by a smaller percentage of calbindin-immunoreactive interneurons compared to monkeys who have greater overall neuronal densities. At the transition from V1 to V2 across all individuals, we found a tendency for increased percentages of calbindin-immunoreactive multipolar cells and calretinin-immunoreactive interneurons. In addition, ...

*Paramesenteric gutters

The descending colon laterally (further left). Peritoneal recesses Paracolic gutters Anatomy photo:37:14-0200 at the SUNY ... This space is defined by: The ascending colon and caecum laterally (further right). The transverse colon superiorly. The root ... Paracolic gutters are recesses between the abdominal wall and the colon. These gutters are clinically important because they ... in the abdominal cavity between the colon and the root of the mesentery. There are two paramesenteric gutters; the left ...

*Left colic vein

The left colic vein drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its ... Ascending branch Descending branch Ronald W. Dudek; Thomas M. Louis (11 February 2014). High-YieldTM Gross Anatomy. Lippincott ...

*Insular cortex

June 2004). "Brain activity during distention of the descending colon in humans". Neurogastroenterol. Motil. 16 (3): 299-309. ...

*Colostomy

People with colostomies who have ostomies of the sigmoid colon or descending colon may have the option of irrigation, which ... Other locations include the ascending, transverse, and descending sections of the colon. Types of colostomy: Loop colostomy: ... Some common reasons are: A section of the colon has been removed, e.g. due to colon cancer requiring a total mesorectal ... A portion of the colon (or large intestine) has been operated upon and needs to be 'rested' until it is healed. In this case ...

*Insular cortex

"Brain activity during distention of the descending colon in humans". Neurogastroenterol. Motil. 16 (3): 299-309. doi:10.1111/j. ...

*Elmer McCollum

He had a number of operations, and finally his descending colon was removed. Again his health improved. McCollum was blind in ...

*Retroperitonium

The lateral boundary of the retroperitoneum is defined by the ascending and descending colon. The retroperitoneum can be ...

*Scrotal ultrasound

... the descending colon distended with feces may compress the left testicular vein. The US appearance of varicocele consists of ... The spermatic cord, which begins at the deep inguinal ring and descends vertically into the scrotum is consists of vas deferens ...

*Defecography

Sigmoidocele is a prolapse of peritoneum that contains a section of sigmoid colon. In females, these prolapses usually descend ... Descending perineum syndrome If the perineum descends >4 cm, descending perineum syndrome may be diagnosed. Fecal incontinence ... The ASCRS textbook of colon and rectal surgery. New York: Springer. pp. 47-52. ISBN 0-387-24846-3. ASCRS: Pelvic Floor ...

*Inferior mesenteric plexus

... which supply the descending and sigmoid parts of the colon; and the superior hemorrhoidal plexus, which supplies the rectum and ...

*Ischemic colitis

Thus, patients without adequate collateralization are at risk for ischemia of the descending and sigmoid colon. Bloody diarrhea ... If blood flow to the colon drops by more than about 50%, ischemia will develop. The arteries feeding the colon are very ... A colonic stricture is a band of scar tissue which forms as a result of the ischemic injury and narrows the lumen of the colon ... The colon receives blood from both the superior and inferior mesenteric arteries. The blood supply from these two major ...

*Erwin Payr

Payr's disease is constipation due to kinking of an adhesion between the transverse and descending colon. Also a tool used in ...

*Talk:Diverticulosis

Inclusion of a diagram of the colon, labeling e.g. 'sigmoid colon', 'ascending colon', 'descending colon','transverse colon' ... The squatting theory is looking better and better, now that Burkitt's hunch about fiber has failed in the case of colon cancer ...

*Left colic artery

From the arches formed by these anastomoses branches are distributed to the descending colon and the left part of the ... course divides into an ascending and a descending branch; the stem of the artery or its branches cross the left ureter and left ... the descending branch anastomoses with the highest sigmoid artery. ... transverse colon. Superior and inferior duodenal fossæ. Duodenojejunal fossa. This article incorporates text in the public ...

*Small intestine

From colon 1 the ascending and transverse colon will be formed and from colon 2 the descending and sigmoid colons and the ... In tetrapods, the ileocaecal valve is always present, opening into the colon. The length of the small intestine is typically ...

*Inferior mesenteric lymph nodes

They drain the descending colon and sigmoid parts of the colon and the upper part of the rectum. Colorectal cancer may ...

*Pararectal lymph nodes

They drain the descending iliac and sigmoid parts of the colon and the upper part of the rectum; their efferents pass to the ...

*Abdomen

... transverse and descending colons, the sigmoid colon and the rectum. Other vital organs inside the abdomen include the liver, ... The left mid-Poupart line corresponds in its upper three-quarters to the inner edge of the descending colon. The right ... It indicates roughly the transverse colon, the lower ends of the kidneys, and the upper limit of the transverse (3rd) part of ... Hollow abdominal organs include the stomach, the small intestine, and the colon with its attached appendix. Organs such as the ...

*Sigmoid arteries

Their branches supply the lower part of the descending colon, the iliac colon, and the sigmoid or pelvic colon; anastomosing ...

*Superior rectal artery

It descends into the pelvis between the layers of the mesentery of the sigmoid colon, crossing the left common iliac artery and ... It divides, opposite the third sacral vertebra into two branches, which descend one on either side of the rectum. About 10 or ... The superior rectal artery (superior hemorrhoidal artery) is an artery that descends into the pelvis to supply blood to the ...

*Large intestine

... the transverse colon, the descending colon, the sigmoid colon and the rectum. Sections of the colon are: The ascending colon ... Of the colon, the ascending colon, descending colon and rectum are retroperitoneal, while the cecum, appendix, transverse colon ... The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. One function of ... The lymph from the distal one-third of the transverse colon, the descending colon, the sigmoid colon, and the upper rectum ...

*Carl Toldt

Lateral reflection of posterior parietal peritoneum of abdomen over the mesentery of the ascending and descending colon. In ...

*Paracolic gutters

... down the lateral aspect of the ascending colon, and around the cecum. It is continuous with the peritoneum as it descends into ... The main paracolic gutter lies lateral to the colon on each side. A less obvious medial paracolic gutter may be formed, ... The paracolic gutters (paracolic sulci, paracolic recesses) are spaces between the colon and the abdominal wall. There are two ... paracolic gutters are peritoneal recesses on the posterior abdominal wall lying alongside the ascending and descending colon. ...

*María Amalia Lacroze de Fortabat

Her mother's family descended from Uruguay's second president, Manuel Oribe. She was raised in Paris and in 1942, having ... Also, she was among the founders of the Fundación Teatro Colón, trustee of the Metropolitan Museum of Art, New York, and a ... Amalia (as she was known) had met Alfredo Fortabat, a divorced industrialist, during a Teatro Colón function, and the two began ...

*Cecum

During a dissection, the colon could be traced from the rectum, to the sigmoid colon, through the descending, transverse, and ... It is also separated from the colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon ... The cecum is an end point for the colon with a dead-end portion terminating with the appendix. The connection between the end ... The connection between the end of the cecum and the beginning of the ascending colon is called the cecocolic orifice. A cecal ...

*Hindgut

In mammals, it includes the distal third of the transverse colon and the splenic flexure, the descending colon, sigmoid colon ... In zoology, the term hindgut refers also to the cecum and ascending colon. Arterial supply is by the Inferior mesenteric artery ...

*Category:Mid-importance Anatomy articles

Talk:Articular branches of descending genicular artery. *Talk:Articular capsule of the knee joint ... Talk:Ascending colon. *Talk:Ascending limb of loop of Henle. *Talk:Ascending lumbar vein ...

*Adventitia

However, at the oral cavity, thoracic esophagus, ascending colon, descending colon and the rectum, the muscularis externa is ...

Combined laparoscopic colectomy and splenectomy for bleeding transverse colon cancer and MDS associated splenomegaly with...Combined laparoscopic colectomy and splenectomy for bleeding transverse colon cancer and MDS associated splenomegaly with...

Combined laparoscopic colectomy and splenectomy for bleeding transverse colon cancer and MDS associated splenomegaly with ... The omentum 10 cm proximal to the tumor in the distal transverse colon was transected. The splenic flexure and descending colon ... The spleen was removed through the mini-incision, the colon was brought out and resected and anastomosed using a two staple ... A 72-year-old male patient presented with MDS associated ITP and splenomegaly and a bleeding colon cancer; combined ...
more infohttp://dmr.amegroups.com/article/view/5611

Descending Colon - Anatomy and PhysiologyDescending Colon - Anatomy and Physiology

Finally, the outermost anterior layer of the descending colon is visceral peritoneum; on the posterior of the descending colon ... The descending colon is a segment of the large intestine and is the third and penultimate segment of the colon. It transports ... During defecation, the descending colon helps to propel feces toward the sigmoid colon and rectum and eventually out of the ... At its superior end, the descending colon connects to the transverse colon at the splenic flexure just inferior to the spleen. ...
more infohttps://www.innerbody.com/image_dige08/dige46.html

Descending colon Anatomy, Diagram & Function | Body MapsDescending colon Anatomy, Diagram & Function | Body Maps

The colon is part of the large intestine, the final part of the digestive system. Its function is to reabsorb fluids and ... The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon. ... The descending colon stores the food to be emptied into the rectum. The colon is held in place by peritoneum, a thin layer of ... The descending colon is located on the left side of the large intestine, extending from the bend below the spleen to the ...
more infohttps://www.healthline.com/human-body-maps/descending-colon/male

PatientsLikeMe | Descending Colon Resection report for  patients like youPatientsLikeMe | Descending Colon Resection report for patients like you

Find the most comprehensive real-world treatment information on Descending Colon Resection at PatientsLikeMe. 0 patients with ... bipolar I disorder or psoriasis currently have Descending Colon Resection. ... What is Descending Colon Resection?. Category: Surgeries false A descending colon resection (colectomy) is a type of surgery ... Stopped having Descending Colon Resection Duration. Patients. This item is relevant to you: Less than 1 month 1 * 1 ...
more infohttps://www.patientslikeme.com/treatments/show/27385-descending-colon-resection-side-effects-and-efficacy

Descending colon - WikipediaDescending colon - Wikipedia

Cancer of the descending colon is a serious disease. A person can have colon cancer yet have no symptoms in the early stages. ... The descending colon is the part of the large intestine from the splenic flexure to the beginning of the sigmoid colon. The ... The descending colon begins at the splenic flexure at the upper left part of the abdomen. It passes downward through the left ... Ulcerative colitis can affect any part of the colon (and other mucosa, such as the mouth), but when it affects the descending ...
more infohttps://en.wikipedia.org/wiki/Descending_colon

Cell Ontology - descending colon - Classes | NCBO BioPortalCell Ontology - descending colon - Classes | NCBO BioPortal

The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending ... The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending ... http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Descending_Colon SYN LOOM ... colon lying in the left iliac fossa is sometimes called the iliac colon. ...
more infohttps://bioportal.bioontology.org/ontologies/CL?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FUBERON_0001158

A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral...A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral...

A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral ... "AJCC: colon and rectum," in AJCC Cancer Staging Manual, S. B. Edge, D. R. Byrd, C. C. Compton, A. G. Fritz, F. L. Greene, and A ... Report of a case," Diseases of the Colon and Rectum, vol. 26, no. 6, pp. 390-392, 1983. View at Google Scholar · View at Scopus ... J.-Y. Yang, J.-K. Lee, S.-M. Cha, and Y.-B. Joo, "Psoas abscess caused by spontaneous rupture of colon cancer," Clinics in ...
more infohttps://www.hindawi.com/journals/cris/2014/128506/ref/

A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral...A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral...

A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral ... Alban Cacurri, Gaspare Cannata, Stefano Trastulli, et al., "A Rare Case of Perforated Descending Colon Cancer Complicated with ...
more infohttps://www.hindawi.com/journals/cris/2014/128506/cta/

Human Colon descending (Normal) tissue lysate  | GeneTexHuman Colon descending (Normal) tissue lysate | GeneTex

Human Colon descending (Normal) tissue lysate, GTX28698, Applications: ELISA, IP, WB; ELISA, Immunoprecipitation, Western Blot ... Human Colon descending (Normal) lysate, Human Colon descending (Normal) tissue extract. Lysate Fraction. Whole Cell Extract/ ... Human Colon descending (Normal) tissue lysate See all Human Colon lysate products ...
more infohttp://www.genetex.com/Human-Colon-descending-Normal-tissue-lysate-GTX28698.html

2006 ICD-9-CM Diagnosis Code 863.53 : Injury to descending (left) colon with open wound into cavity2006 ICD-9-CM Diagnosis Code 863.53 : Injury to descending (left) colon with open wound into cavity

Short description: DESCENDING COLON INJ-OPN.. *ICD-9-CM 863.53 is a billable medical code that can be used to indicate a ... Injury to descending (left) colon with open wound into cavity. * ... colon 863.40. *. with*. open wound into cavity 863.50. *. ... 2015/16 ICD-10-CM S36.502A Unspecified injury of descending [left] colon, initial encounter ...
more infohttp://www.icd9data.com/2006/Volume1/800-999/860-869/863/863.53.htm

Proliferative Enteropathy (PE)-Induced Changes in the Calbindin-Immunoreactive (CB-IR) Neurons of Inferior Mesenteric Ganglion...Proliferative Enteropathy (PE)-Induced Changes in the Calbindin-Immunoreactive (CB-IR) Neurons of Inferior Mesenteric Ganglion...

The retrograde tracer fast blue (FB) was injected into the descending colons of all animals and then tissue comprising IMGs ... neurons projecting to the colon exhibit calbindin-like immunoreactivity. It is not known if there are any changes in the ... Neurons in the ENS of the Porcine Descending Colon. *Krystyna Makowska, Kazimierz Obremski, Lukasz Zielonka, Slawomir Gonkowski ... distribution in intramural nervous structures of the porcine descending colon. *Slawomir Gonkowski, Krystyna Makowska, Jaroslaw ...
more infohttps://www.semanticscholar.org/paper/Proliferative-Enteropathy-%28PE%29%E2%80%94Induced-Changes-in-Wojtkiewicz-R%C3%B3wniak/36fc7218ccce0d8a5fefbdbd8afbed73ce04f7ab

2018 ICD-10-CM Diagnosis Code C18.6: Malignant neoplasm of descending colon2018 ICD-10-CM Diagnosis Code C18.6: Malignant neoplasm of descending colon

Malignant neoplasm of descending colon. 2016 2017 2018 Billable/Specific Code *C18.6 is a billable/specific ICD-10-CM code that ... Primary malignant neoplasm of descending colon. ICD-10-CM C18.6 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0): * ... Malignant neoplasm of colon. 2016 2017 2018 Non-Billable/Non-Specific Code Type 1 Excludes*malignant carcinoid tumors of the ... Cancer of the colon, descending. *Primary adenocarcinoma of descending colon. * ...
more infohttp://www.icd10data.com/ICD10CM/Codes/C00-D49/C15-C26/C18-/C18.6

Descending ColonDescending Colon

... by Etienne Moore - last modified 2007-04-02 18:09 ... This is part of the left colon lying in the left side of the abdomen. ...
more infohttp://www.sussexsurgery.com/definitions-1/descending-colon

Descending Colon | ANATOMIC.USDescending Colon | ANATOMIC.US

... transverse colon, splenic flexure, descending colon, and sigmoid colon. The descending colon passes down through the upper back ... The descending colon is a part of the colon, which is made up of several parts. They include the ascending colon, hepatic ... Descending Colon The descending colon of humans passes downward through the left hypochondrium and lumbar regions, along the ... Cancer of the descending colon is the most serious of the diseases. A person can have colon cancer yet have no symptoms in the ...
more infohttp://beta.anatomic.us/atlas/descending-colon/

Tumor in the descending colonTumor in the descending colon

... GeneralEquipmentPreparationImplementationFollow-up. General. For cancer in the descending colon ... Oncolex - cancer encyclopedia › About cancer in the colon/rectum › Treatment › Surgery colon › Tumor in descending ... Surgery colonTumor in cecum and ascending Tumor in right flexure Tumor in transversumTumor in left flexure Tumor in descending ... The bowel is divided to the left on the transverse colon and upwards on the rectum. The distal sigmoid colon is not being ...
more infohttp://oncolex.org/Colorectal-cancer/Procedures/TREATMENT/Kirurgi/Tykktarm_Desendens?lg=procedure

Diagram descending colon - Bowtrol colon cleanser - Nov 27, 2017Diagram descending colon - Bowtrol colon cleanser - Nov 27, 2017

Diagram descending colon - Abdomen - Wikipedia, the free encyclopedia. Bowtrol is formulated to maximize ones elimination ... The colon and rectum are parts of the digestive... ascending colon, transverse colon, descending colon, and sigmoid colon... ... CARCINOMA OF THE COLON. STAGING DIAGRAM. SITE: Ascending Colon. Cecum Colon, NOS Descending Colon Hepatic Flexure of Colon. ... The last part of the colon. The distal colon includes the descending colon (the left side of the colon) and the sigmoid colon ( ...
more infohttp://bowtrolcoloncleanse.drug-purchase.info/diagram-descending-colon.html

ICD-10 Code: D12.4  - Benign neoplasm of descending colonICD-10 Code: D12.4 - Benign neoplasm of descending colon

The ICD-10 Code D12.4 is the code used for Benign neoplasm of descending colon .An alternative description for this code is ...
more infohttp://medpricemonkey.com/icd10_code?icd10_code=D12.4

Bowel - large bowel - descending colon - sigmoid Emotions , Personal DevelopmentBowel - large bowel - descending colon - sigmoid Emotions , Personal Development

It is located at the end of the left colon ... The sigmoid is the area of the descending colon (before the ... descending colon - sigmoid. Published on Digestive system.. The sigmoid is the area of the descending colon (before the rectum ... It is located at the end of the left colon or descending colon, followed by the rectum and the anus. ... Cancer of the descending colon is more frequent in the sigmoid and the rectum. ...
more infohttp://www.flowsandforms.com/bowel-large-bowel-descending-colon-sigmoid/

Colon Cancer Right & Left Symptoms | LIVESTRONG.COMColon Cancer Right & Left Symptoms | LIVESTRONG.COM

Colon cancer is a potentially curable disease if it is caught in the early stages. This is the reason the American Cancer ... transverse colon, descending or left colon, and the sigmoid colon. The sigmoid colon is considered a part of the left colon. ... Descending Colon Symptoms. The symptoms of left-sided colon cancer are attributed the anatomy of that area of the colon. The ... The symptoms of colon cancer vary according to location of the cancer within the colon as well as any spread outside the colon ...
more infohttps://www.livestrong.com/article/132774-colon-cancer-right-left-symptoms/

ICD-10-CM Code C18.6 - Malignant neoplasm of descending colonICD-10-CM Code C18.6 - Malignant neoplasm of descending colon

Malignant neoplasm of descending colon BILLABLE Billable Code Billable codes are sufficient justification for admission to an ... C18.6 is a billable ICD code used to specify a diagnosis of malignant neoplasm of descending colon. A billable code is ... ICD-10-CM Neoplasms Index References for C18.6 - Malignant neoplasm of descending colon The ICD-10-CM Neoplasms Index links ... Colorectal cancer (also known as colon cancer, rectal cancer, or bowel cancer) is the development of cancer in the colon or ...
more infohttps://icd.codes/icd10cm/C186

Descending Colon  < Colon  << Large Intestines  <<< Lower Gastrointestinal Tract  @...Descending Colon < Colon << Large Intestines <<< Lower Gastrointestinal Tract @...

Descending Colon "Descending Colon" In our bodys large intestine, the Descending Colon is the segment of the colon, between ... the Transverse Colon and the sigmoid colon.. In our bodys colon, the Descending Colon passes downward through the left ... Descending Colon ⌊Body Sciences. ⌊Body Systems (Organ Systems). ⌊Digestive Organ System. ⌊Alimentary System (Gastrointestinal ... and then descends, in the angle between psoas and quadratus lumborum, to the crest of the ilium, where it ends in the sigmoid ...
more infohttp://wellnessadvocate.com/?uid=43371

Intestines ascending, transverse and descending colon pieces H174 Chocolate Candy MoldIntestines ascending, transverse and descending colon pieces H174 Chocolate Candy Mold

... transverse and descending colon pieces H174 Chocolate Candy Mold, Cavities: 5, Mold Type: Pieces/MintsHeight: 1 9/16Width: 1 11 ... transverse and descending colon pieces H174 Chocolate Candy Mold (BODY PARTS). Intestines ascending, ... Intestines ascending, transverse and descending colon pieces H174 Chocolate Candy Mold. Our Products: Chocolate Molds > BODY ... Intestines ascending, transverse and descending colon pieces H174 Chocolate Candy Mold, Cavities: 5, Mold Type: Pieces/Mints. ...
more infohttps://www.kakekreations.com/store/pc/Intestines-ascending-transverse-and-descending-colon-pieces-H174-Chocolate-Candy-Mold-p2611.htm

Efferent limb of the coronary vasoconstrictor reflex elicited by distension of the descending colon in anesthetized dogs<...Efferent limb of the coronary vasoconstrictor reflex elicited by distension of the descending colon in anesthetized dogs<...

Distension of the descending colon elicits reflex coronary vasoconstriction. To study the efferent branch of this reflex, ... A pouch was formed from the distal 15 cm of the descending colon and distended at constant pressure (54 ± 8.9 mmHg) with warm ... A pouch was formed from the distal 15 cm of the descending colon and distended at constant pressure (54 ± 8.9 mmHg) with warm ... A pouch was formed from the distal 15 cm of the descending colon and distended at constant pressure (54 ± 8.9 mmHg) with warm ...
more infohttps://moh-it.pure.elsevier.com/en/publications/efferent-limb-of-the-coronary-vasoconstrictor-reflex-elicited-by-

Resection and anastomosis of the descending colon in 43 horses.<...Resection and anastomosis of the descending colon in 43 horses.<...

Resection and anastomosis of the descending colon in 43 horses.. Timo Prange, Susan J. Holcombe, Jennifer A. Brown, Julie E. ... Resection and anastomosis of the descending colon in 43 horses. / Prange, Timo; Holcombe, Susan J.; Brown, Jennifer A.; Dechant ... Resection and anastomosis of the descending colon in 43 horses. Veterinary surgery : VS : the official journal of the American ... title = "Resection and anastomosis of the descending colon in 43 horses.",. abstract = "To determine (1) the short- (to ...
more infohttps://ucdavis.pure.elsevier.com/en/publications/resection-and-anastomosis-of-the-descending-colon-in-43-horses
  • Feces passing through the descending colon are stored until they are ready to be eliminated from the body. (innerbody.com)
  • The walls of the descending colon absorb water as well as remaining nutrients and vitamins from the feces, depositing these valuable substances into our bloodstream. (innerbody.com)
  • It contains many small pouches, known as haustra, along its length that increase its surface area and help to move feces through the colon. (innerbody.com)
  • The mucus secreted from goblet cells in the mucosa layer provides lubrication to feces moving through the lumen, protecting the delicate tissues of the colon. (innerbody.com)
  • By the time feces reach the descending colon, the vast majority of nutrients, vitamins and water have been extracted by the ascending and transverse colon, leaving mostly waste products. (innerbody.com)
  • Still, some absorption of water and vitamins produced by bacterial fermentation of feces - including vitamins K, B1, B2 and B12 - does occur in the descending colon. (innerbody.com)
  • Symptoms on the left side of the colon are usually caused by growth outward into the lumen, obstructing the flow of feces. (livestrong.com)
  • The colon takes water from the feces that goes through it. (wikipedia.org)
  • During distensions of the colon, arterial blood pressure and heart rate were kept constant by the withdrawal of blood and pacing of the heart, respectively. (elsevier.com)
  • Arterial supply to the colon comes from branches of the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). (colonoscopyandendoscopybilling.com)
  • The colon is held in place by peritoneum, a thin layer of tissue that supports the abdominal organs. (healthline.com)
  • It receives waste from the colon and stores it until it passes out of the body through the anus. (cancer.ca)
  • Chemotherapy can cause painful ulcers, bleeding and infection in the esophagus , colon and vagina . (cancer.ca)
  • A case of mucinous adenocarcinoma of the colon presenting with psoas abscess," The Korean Journal of Gastroenterology , vol. 52, no. 2, pp. 120-123, 2008. (hindawi.com)