Colon, Ascending
Colon, Transverse
HT29 Cells
Azoxymethane
Intestinal Mucosa
Colonic Diseases
Colorectal Neoplasms
1,2-Dimethylhydrazine
Colitis
Tumor Cells, Cultured
Caco-2 Cells
Carcinogens
Gene Expression Regulation, Neoplastic
Cecum
Dextran Sulfate
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Mice, Nude
Precancerous Conditions
Butyrates
Anticarcinogenic Agents
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Intestinal Polyps
Colitis, Ulcerative
Intestine, Large
beta Catenin
A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
Immunohistochemistry
Carcinoma
Genes, APC
Aberrant Crypt Foci
Sigmoid Diseases
Cell Division
Neoplasm Transplantation
Intestines
Carcinoembryonic Antigen
Enema
Mucins
Ileum
Reverse Transcriptase Polymerase Chain Reaction
Feces
Intestine, Small
Fluorouracil
Blotting, Western
Cyclooxygenase 2
Neoplasm Proteins
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Adenomatous Polyposis Coli
Tumor Markers, Biological
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Dose-Response Relationship, Drug
Microsatellite Instability
Intestinal Obstruction
Adenomatous Polyposis Coli Protein
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Diverticulitis, Colonic
Neoplasm Staging
Barium Sulfate
Neoplasms
Dietary Fiber
Sulindac
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Muscle, Smooth
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Disease Models, Animal
Drug Screening Assays, Antitumor
Inflammatory Bowel Diseases
Cell Transformation, Neoplastic
Mucin-2
Neoplasms, Experimental
Digestive System
Megacolon
Epithelial Cells
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
Neoplasm Metastasis
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Cell Survival
Myenteric Plexus
One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)
Xenograft Model Antitumor Assays
Down-Regulation
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Prostaglandin-Endoperoxide Synthases
Transfection
Antigens, Neoplasm
Immunoenzyme Techniques
Base Sequence
Up-Regulation
Fatty Acids, Volatile
Mutation
Anastomosis, Surgical
Deoxycholic Acid
DNA Methylation
Colitis, Ischemic
Gastrointestinal Tract
Gene Expression
Cell Cycle
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
Jejunum
Tissue Distribution
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Levamisole
An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
Rats, Wistar
Crohn Disease
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
Gene Expression Profiling
Prognosis
Isoenzymes
Chemotherapy, Adjuvant
Camptothecin
Genes, ras
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
Tumor Suppressor Protein p53
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Risk Factors
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Rats, Sprague-Dawley
Organoplatinum Compounds
Adenoma, Villous
Piroxicam
Cell Movement
Membrane Proteins
Leucovorin
Neoplasms, Multiple Primary
Plant Extracts
Promoter Regions, Genetic
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Peristalsis
Flow Cytometry
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Colonic Diseases, Functional
Colonography, Computed Tomographic
Antineoplastic Agents, Phytogenic
Stomach
Ileostomy
Senna Extract
RNA, Small Interfering
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
DNA Mismatch Repair
A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)
Butyric Acid
Cyclooxygenase 2 Inhibitors
Thymidylate Synthase
Intestinal Polyposis
Curcumin
Oligonucleotide Array Sequence Analysis
Dinoprostone
Enzyme Inhibitors
Submucous Plexus
One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)
Microsatellite Repeats
Gastrointestinal Neoplasms
Cytoskeletal Proteins
Cyclooxygenase Inhibitors
Diverticulosis, Colonic
Bifidobacterium
Mice, SCID
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
TCF Transcription Factors
Wnt Proteins
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
Adenocarcinoma, Mucinous
Proto-Oncogene Proteins
Antigens, Tumor-Associated, Carbohydrate
Disease Progression
Drug Resistance, Neoplasm
Cell Differentiation
DNA Primers
Treatment Outcome
Muscle Contraction
Body Weight
Colorectal Neoplasms, Hereditary Nonpolyposis
A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.
A smooth muscle tone-dependent stretch-activated migrating motor pattern in isolated guinea-pig distal colon. (1/35)
We have investigated the tone dependence of the intrinsic nervous activity generated by localized wall distension in isolated segments of guinea-pig distal colon using mechanical recordings and video imaging of wall movements. A segment of colon was threaded through two partitions, which divided the colon for pharmacological purposes into oral, stimulation and anal regions. An intraluminal balloon was located in the stimulation region between the two partitions (12 mm apart). Maintained colonic distension by an intraluminal balloon or an artificial faecal pellet held at a fixed location generated rhythmic (frequency 0.3 contractions min(-1); duration approximately 60 s) peristaltic waves of contraction. Video imaging of colonic wall movements or the selective application of pharmacological agents suggested that peristaltic waves originated just oral (< or = 4 mm) to the pellet and propagated both orally (approximately 11 mm s(-1)) and anally (approximately 1 mm s(-1)). Also, during a peristaltic wave the colon appears to passively shorten in front of a pellet, as a result of an active contraction of the longitudinal muscle oral to the pellet. Faecal pellet movement only occurred when a rhythmic peristaltic wave was generated. Rhythmic peristaltic waves were abolished in all regions by the smooth muscle relaxants isoproterenol (1 microM), nicardipine (1 microM) or papavarine (10 microM), and by the neural antagonists tetrodotoxin (TTX; 0.6 microM), hexamethonium (100 microM) or atropine (1 microM), when added selectively to the stimulation region. Nicardipine, atropine, TTX, or hexamethonium (100 microM) also blocked the evoked peristaltic waves when selectively added to the oral region. Nomega-nitro-L-arginine (L-NA; 100 microM) added to the anal region reduced the anal relaxation but increased the anal contraction, leading to an increase in the apparent conduction velocity of each peristaltic wave. In conclusion, maintained distension by a fixed artificial pellet generates propulsive, rhythmic peristaltic waves, whose enteric neural activity is critically dependent upon smooth muscle tone. These peristaltic waves usually originate just oral to the pellet, and their apparent conduction velocity is generated by activation of descending inhibitory nerve pathways. (+info)Distinguishing right from left colon by the pattern of gene expression. (2/35)
Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis. These differences may reflect distinct biological characteristics of proximal and distal colonic mucosa, acquired in embryonic or postnatal development, that determine a differential response to uniformly distributed environmental factors. Alternatively, the differences in the epidemiology of proximal and distal CRCs could result from the presence of different procarcinogenic factors in the ascending versus descending colon, acting on cells with either similar or distinct biological characteristics. We applied cDNA microarray technology to explore the possibility that mucosal epithelium from adult proximal and distal colon can be distinguished by their pattern of gene expression. In addition, gene expression was studied in fetal (17-24 weeks gestation) proximal and distal colon. More than 1000 genes were expressed differentially in adult ascending versus descending colon, with 165 genes showing >2-fold and 49 genes showing >3-fold differences in expression. With almost complete concordance, biopsies of adult colonic epithelium can be correctly classified as proximal or distal by gene expression profile. Only 87 genes were expressed differently in ascending and descending fetal colon, indicating that, although anatomically relevant differences are already established in embryonic colon, additional changes in gene expression occur in postnatal development. (+info)Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/35)
1. Mechanisms involved in Ca(2+) sensitization of contractile elements induced by the activation of muscarinic receptors in membrane-permeabilized preparations of the rat proximal and distal colon were studied. 2. In alpha-toxin-permeabilized preparations from the rat proximal and distal colon, Ca(2+) induced a rapid phasic and subsequent tonic component. After Ca(2+)-induced contraction reached a plateau, guanosine 5'-triphosphate (GTP) and carbachol (CCh) in the presence of GTP further contracted preparations of both the proximal and distal colon (Ca(2+) sensitization). Y-27632, a rho-kinase inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization more significantly in the proximal colon than in the distal colon. 3. Y-27632 at 10 microm had no effect on Ca(2+)-induced contraction or slightly inhibited phorbol-12,13-dibutyrate-induced Ca(2+) sensitization in either proximal or distal colon. Chelerythrine, a protein kinase C inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization in the distal colon, but not in the proximal colon. The component of Ca(2+) sensitization that persisted after the chelerythrine treatment was completely inhibited by Y-27632. 4. In beta-escin-permeabilized preparations of the proximal colon, C3 exoenzyme completely inhibited GTP plus CCh-induced Ca(2+) sensitization, but PKC(19-31) did not. In the distal colon, C3 exoenzyme abolished GTP-induced Ca(2+) sensitization. It inhibited CCh-induced sensitization by 50 % and the remaining component was inhibited by PKC(19-31). 5. These results suggest that both protein kinase C and rho pathways in parallel mediate the Ca(2+) sensitization coupled to activation of muscarinic receptors in the rat distal colon, whereas the rho pathway alone mediates this action in the proximal colon. (+info)Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/35)
BACKGROUND: Because of their suggested link with microsatellite instability high colorectal cancers, right sided hyperplastic polyps (HPs) may differ from their distally located counterparts. This is highlighted by the recognition of a variant HP, termed sessile serrated adenoma (SSA), which predominates in the proximal colon. HPs displaying the morphological features now associated with SSAs have been shown to have altered expression of "cancer associated" markers, but no studies have investigated whether this is dependent on anatomical location of the polyps. AIMS: To evaluate morphological and functional features in right versus left sided HPs from patients without colorectal cancer with the aim of identifying distinguishing characteristics. METHODS: HPs originating in the proximal and distal colorectum were histochemically and immunohistochemically stained to evaluate a panel of markers related to proliferation and differentiation. In addition, a series of morphological features was evaluated for each polyp. RESULTS: Crypt serration, crypt dilatation, and horizontal crypt growth were more common among HPs from the right side, whereas histochemical factors including mucin changes, global methylation status, and expression of carcinoembryonic antigen were not significantly different. An age disparity was also seen between patients with right versus left sided lesions, with patients with right sided lesions being an average of more than 10 years younger than those with left sided lesions. CONCLUSIONS: These findings suggest that right and left sided HPs differ mainly in terms of growth regulation rather than cellular differentiation, implying that these lesions belong to a continuous spectrum of serrated polyps that differ quantitatively rather than qualitatively. (+info)Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy. (5/35)
AIM: To review the risk of proximal colon cancer in patients undergoing colonoscopy. METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination). Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma). The sites of neoplasms were defined as rectosigmoid (rectum and sigmoid colon) and proximal colon (from cecum to descending colon). RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings. Among the 157 patients with proximal colon cancer, 74% had no neoplasm in the rectosigmoid colon. Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer. CONCLUSION: Sigmoidoscopy is inadequate for colorectal cancer screening, especially in older populations. (+info)Withdrawing method of the stiffening tube incidentally inserted into the descending colon. (6/35)
We experienced a very rare complication of colonoscopy, a migration of stiffening tube into the colorectum. We herein introduce a withdrawing method of migrating stiffening tube incidentally inserted into the colorectum. A 65-year-old Japanese woman underwent colonoscopy because of abdominal discomfort. We used stiffening tube to insert the scope to the proximal colon because of her redundant sigmoid colon. When withdrawing the scope, we realized that the tube was fully inside the colorectum. We could not remove the tube instantly, and it reached the splenic flexure, finally. We reinserted the scope through the migrating tube, straightened the scope, and withdrew it holding a slight angle of the scope over the proximal end of the tube. Then, we could safely remove the tube along with the scope through the anus. (+info)Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (7/35)
BACKGROUND: Despite the fact that the alimentary tract is part of the body's first line of defense against orally ingested xenobiotica, little is known about the distribution and expression of cytochrome P450 (CYP) enzymes in human colon. Therefore, expression and protein levels of four representative CYPs (CYP2C(8), CYP2E1, CYP3A4, and CYP3A5) were determined in human colon mucosa biopsies obtained from ascending, descending and sigmoid colon. METHODS: Expression of CYP2C, CYP2E1, CYP3A4, and CYP3A5 mRNA in colon mucosa was determined by RT-PCR. Protein concentration of CYPs was determined using Western blot methods. RESULTS: Extensive interindividual variability was found for the expression of most of the genes. However, expression of CYP2C mRNA levels were significantly higher in the ascending colon than in the sigmoid colon. In contrast, mRNA levels of CYP2E1 and CYP3A5 were significantly lower in the ascending colon in comparison to the descending and sigmoid colon. In sigmoid colon protein levels of CYP2C8 were significantly higher by ~73% than in the descending colon. In contrast, protein concentration of CYP2E1 was significantly lower by ~81% in the sigmoid colon in comparison to the descending colon. CONCLUSION: The current data suggest that the expression of CYP2C, CYP2E1, and CYP3A5 varies in different parts of the colon. (+info)Comparative study of descendent colon rupture resistance considering traction force of rupture and total energy of rupture in rats. (8/35)
PURPOSE: To compare total energy of rupture and traction force of rupture tests within a rupture resistance study of descendent colon of rats. METHODS: Twelve descendent colon segments of rats were considered to perform the study. For each one of the specimens, total energy of rupture and traction force of rupture necessary to promote colic wall burst were evaluated through the biomechanical total energy of rupture test using the Biomechanical Data Acquisition and Analysis System, version 2.0. Average, standard deviation, standard error of average and coefficient of variation were considered for analysis of results. RESULTS: Traction force of rupture average, standard deviation, standard error of average and coefficient of variation were 380.05 gf, 98.74, 28.5 e 25.98%, respectively while total energy of rupture presented average of 244.85 gf, standard deviation of 57.76, standard error of average of 16.67 and coefficient of variation of 23.59. CONCLUSION: Although, total energy of rupture considered a larger number of attributes to its calculation related to non-linear viscoelastic materials, such as colic wall, it presented a smaller coefficient of variation when compared to traction force of rupture, thus demonstrating to constitute a possible parameter to analyze intestinal resistance of rats. (+info)
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Paramesenteric gutters
The descending colon laterally (further left). Peritoneal recesses Paracolic gutters Anatomy photo:37:14-0200 at the SUNY ... This space is defined by: The ascending colon and caecum laterally (further right). The transverse colon superiorly. The root ... Paracolic gutters are recesses between the abdominal wall and the colon. These gutters are clinically important because they ... in the abdominal cavity between the colon and the root of the mesentery. There are two paramesenteric gutters; the left ...
Left colic vein
The left colic vein drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its ... Ascending branch Descending branch Ronald W. Dudek; Thomas M. Louis (11 February 2014). High-YieldTM Gross Anatomy. Lippincott ...
Segmental colitis associated with diverticulosis
The descending and sigmoid colon are typically involved. Biopsies of the affected area and the unaffected rectum confirm the ... Computed tomography of the abdomen is not routinely necessary, but may show thickening or inflammation in the distal colon ( ... Fecal calprotectin, a marker of colon inflammation, may be elevated in individuals with SCAD. Fecal calprotectin may assist in ... However, ulcerative colitis usually affects the rectum and inflammation in IBD extends to areas of the colon without ...
Insular cortex
June 2004). "Brain activity during distention of the descending colon in humans". Neurogastroenterol. Motil. 16 (3): 299-309. ...
List of ETA attacks
February 6, 1986: Rear Admiral Cristóbal Colón de Carvajal y Maroto and his driver; the Rear Admiral, descended from Cristóbal ... Asesinados en Madrid el vicealmirante Colón de Carvajal y su conductor en un atentado en el que fue herido el comandante ... Colón. June 17, 1986: 3 members of Spanish army are shot dead inside a car while driving through Madrid. July 14, 1986: Plaza ...
Colostomy
People with colostomies who have ostomies of the sigmoid colon or descending colon may have the option of irrigation, which ... Other locations include the ascending, transverse, and descending sections of the colon. Pouches and the stick-on appliances to ... Some common reasons are: A part of the colon has been removed, e.g. due to colon cancer requiring a total mesorectal excision, ... A part of the colon has been operated upon and needs to be 'rested' until it is healed. In this case, the colostomy is often ...
Elmer McCollum
He had a number of operations, and finally his descending colon was removed. Again his health improved. McCollum was blind in ...
Retroperitonium
The lateral boundary of the retroperitoneum is defined by the ascending and descending colon. The retroperitoneum can be ...
Duodenal-type follicular lymphoma
... colon and rectum, each 2 patients; and stomach and esophagus, no patients. Lesions were limited to the second part of the ... descending) part of the duodenum, 54 patients; combined third (i.e. horizontal or inferior), and fourth (i.e. ascending) part ...
Defecography
Sigmoidocele is a prolapse of peritoneum that contains a section of sigmoid colon. In females, these prolapses usually descend ... Descending perineum syndrome If the perineum descends >4 cm, descending perineum syndrome may be diagnosed. Fecal incontinence ... al.], senior editors, Bruce G. Wolff ... [et (2007). The ASCRS textbook of colon and rectal surgery. New York: Springer. pp. 47 ...
Inferior mesenteric plexus
... which supply the descending and sigmoid parts of the colon; and the superior hemorrhoidal plexus, which supplies the rectum and ...
Ischemic colitis
Thus, patients without adequate collateralization are at risk for ischemia of the descending and sigmoid colon. Bloody diarrhea ... If blood flow to the colon drops by more than about 50%, ischemia will develop. The arteries feeding the colon are very ... The colon receives blood from both the superior and inferior mesenteric arteries. The blood supply from these two major ... Finally, a shock phase can develop as fluids start to leak through the damaged colon lining. This can result in shock and ...
Rectum
The rectum receives fecal material from the descending colon, transmitted through regular muscle contractions called ... The rectum joins with the sigmoid colon at the level of S3, and joins with the anal canal as it passes through the pelvic floor ... Colon and Rectum" (PDF), AJCC Cancer Staging Atlas, American Joint Committee on Cancer, 2006, p. 109 Wolff BG, Fleshman JW, ... The rectum is a continuation of the sigmoid colon, and connects to the anus. The rectum follows the shape of the sacrum and ...
Erwin Payr
Payr's disease is constipation due to kinking of an adhesion between the transverse and descending colon. Also a tool used in ...
Newick format
This is done by adding additional :[bootstrap]:[prob] fields after the length; fields can be left empty as long as the colons ... production in those cases where having the entire tree descended from nowhere is permitted; this captures the replaced ... An unquoted string may not contain blanks, parentheses, square brackets, single_quotes, colons, semicolons, or commas. ... and colon) are prohibited. The Tree → Subtree ";" production is instead the Tree → Branch ";" ...
Inferior mesenteric lymph nodes
They drain the descending colon and sigmoid parts of the colon and the upper part of the rectum. Colorectal cancer may ...
Inferior mesenteric artery
The regions supplied by the IMA are the descending colon, the sigmoid colon, and part of the rectum. Proximally, its territory ... The SMA and IMA anastomose via the marginal artery of the colon (artery of Drummond) and via Riolan's arcade (also called the " ... All these arterial branches further divide into arcades which then supply the colon at regular intervals. The IMA is ... supplying the large intestine from the distal transverse colon to the upper part of the anal canal. ...
Insular cortex
"Brain activity during distention of the descending colon in humans". Neurogastroenterol. Motil. 16 (3): 299-309. doi:10.1111/j. ...
Abdomen
... transverse and descending colons, the sigmoid colon and the rectum. Other vital organs inside the abdomen include the liver, ... The left mid-Poupart line corresponds in its upper three-quarters to the inner edge of the descending colon. The right ... It indicates roughly the transverse colon, the lower ends of the kidneys, and the upper limit of the transverse (3rd) part of ... The abdominal cavity contains most organs of the digestive system, including the stomach, the small intestine, and the colon ...
Sigmoid arteries
Their branches supply the lower part of the descending colon, the iliac colon, and the sigmoid or pelvic colon; anastomosing ...
Taenia coli
In the caecum, the ascending colon, the descending colon and sigmoid colon the positions of these bands are fixed. They are- ... descending and sigmoid colon, but is situated on the anterosuperior surface of transverse colon where layers three and four of ... descending and sigmoid colon, but is placed inferiorly in the transverse colon - Second taenia, taenia mesocolica is present on ... descending and sigmoid colon, but is placed posteriorly on transverse colon at the site of attachment of transverse mesocolon ...
Abdominal pain
The hindgut contains the distal half of the transverse colon, descending colon, sigmoid colon, rectum, and superior anal canal ... The midgut contains portions of the duodenum (distal), cecum, appendix, ascending colon, and first half of the transverse colon ... colon cancer Other: pneumonia, Fitz-Hugh-Curtis syndrome Left upper quadrant Splenomegaly Colon: bowel obstruction, functional ... sigmoid colon volvulus, bowel obstruction, gas accumulation, Toxic megacolon Right low back pain Liver: hepatomegaly Kidney: ...
Pancreas
In front of the pancreas sits the transverse colon. The pancreas narrows towards the tail, which sits near to the spleen. It is ... Surrounded by a muscle, the sphincter of Oddi, this opens into the descending part of the duodenum. The head of the pancreas ... The peritoneum sits on top of the body of the pancreas, and the transverse colon in front of the peritoneum. Behind the ... In front sits the peritoneal membrane and the transverse colon. A small uncinate process emerges from below the head, situated ...
Carl Toldt
Lateral reflection of posterior parietal peritoneum of abdomen over the mesentery of the ascending and descending colon. The ...
Talk:Diverticulosis
Inclusion of a diagram of the colon, labeling e.g. 'sigmoid colon', 'ascending colon', 'descending colon','transverse colon' ... The squatting theory is looking better and better, now that Burkitt's hunch about fiber has failed in the case of colon cancer ...
Cecum
During a dissection, the colon could be traced from the rectum, to the sigmoid colon, through the descending, transverse, and ... It is also separated from the colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon ... The cecum is an end point for the colon with a dead-end portion terminating with the appendix. The connection between the end ... It receives chyme from the ileum, and connects to the ascending colon of the large intestine. It is separated from the ileum by ...
Hindgut
In mammals, it includes the distal third of the transverse colon and the splenic flexure, the descending colon, sigmoid colon ... In zoology, the term hindgut refers also to the cecum and ascending colon. Arterial supply is by the inferior mesenteric artery ...
Adventitia
However, at the oral cavity, thoracic esophagus, ascending colon, descending colon and the rectum, the muscular layer is ...
Left colic artery
From the arches formed by these anastomoses branches are distributed to the descending colon and the left part of the ... After a short, but variable, course, it divides into an ascending and a descending branch. The stem of the artery or its ... the descending branch anastomoses with the highest sigmoid artery. ... transverse colon. The left colic artery may be ligated during abdominal surgery to remove colorectal cancer. This may have ...
Small intestine
From colon 1 the ascending and transverse colon will be formed and from colon 2 the descending and sigmoid colons and the ... In tetrapods, the ileocaecal valve is always present, opening into the colon. The length of the small intestine is typically ...
Category:Mid-importance Anatomy articles
Talk:Articular branches of descending genicular artery. *Talk:Articular capsule of the knee joint ... Talk:Ascending colon. *Talk:Ascending limb of loop of Henle. *Talk:Ascending lumbar vein ...
Reptile
Because of this, many reptiles use the colon to aid in the reabsorption of water. Some are also able to take up water stored in ... "In states of ecstasy, lords dance a serpent dance; great descending snakes adorn and support buildings from Chichen Itza to ... Reptiles are tetrapod vertebrates, creatures that either have four limbs or, like snakes, are descended from four-limbed ...
গলবিল - উইকিপিডিয়া
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
পাকস্থলী - উইকিপিডিয়া
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
Lactose intolerance
... passes intact into the colon[citation needed]. Bacteria in the colon can metabolise lactose, and the resulting fermentation ... One was that most European-descended populations have a low incidence of lactose intolerance[84] and an extensive cultural ... and it reaches the colon. The bacteria in the colon, mixed with the lactose, cause acidity in stools. Stools passed after the ... The unabsorbed sugars and fermentation products also raise the osmotic pressure of the colon, causing an increased flow of ...
Ashkenazi Jews
... who descend from Jews who settled in the Iberian Peninsula, and Mizrahi Jews, who descend from Jews who remained in the Middle ... Healthcare professionals are often taught to consider those of Ashkenazi descent to be at increased risk for colon cancer.[171] ... In the late 19th century, it was proposed that the core of today's Ashkenazi Jewry are genetically descended from a ... Was the great Eastern European Jewry of the 19th century preponderantly descended (as is normally believed) from immigrants ...
Human digestive system
... which includes the distal 1/3 of the transverse colon, descending colon, sigmoid colon, rectum, and the anus above the ... In the large intestine,[2] the passage of the digesting food in the colon is a lot slower, taking from 30 to 40 hours until it ... ascending colon, and the proximal 2/3 of the transverse colon. ... The largest part of the GI tract is the colon or large ... Some vitamins, such as biotin and vitamin K produced by bacteria in the gut flora of the colon are also absorbed. ...
Zotika mirov - Wîkîpediya
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
மனித இரையகக் குடற்பாதை - தமிழ் விக்கிப்பீடியா
குறுக்குக் குடலின் இறுதி மூன்றில் ஒரு பகுதி, இறங்கு பெருங்குடல் (descending colon), மலக்குடல் (rectum), மலத்துவாரத்தின் ... Ascending colon), குறுக்குப் பெருங்குடலின் மூன்றில் இரு பகுதி ...
Arabian horse
... descended from Heaven and awakened Ishmael with a "wind-spout" that whirled toward him. The Angel then commanded the ... Significant among the private breeders in continental Europe was Spain's Cristóbal Colón de Aguilera, XV Duque de Veragua, a ... discussing whether some horses descend from "impure" animals that cannot be traced to the desert Bedouin.[190] The major ... are those horses in North America that can reasonably be assumed to descend entirely from bedouin Arabian horses bred by horse- ...
Garifuna
While they are ancestrally and genealogically descended from groups that migrated from Lesser Antilles, many Garifuna today are ... Mirtha Colón. *Abraham Laboriel. *Abe Laboriel Jr.. *Aurelio Martinez. *Bernard Martínez Valerio ...
Urethra
In the human female, the urethra is about 1.9 inches (4.8 cm) to 2 inches (5.1 cm) long and exits the body between the clitoris and the vagina, extending from the internal to the external urethral orifice. The meatus is located below the clitoris. It is placed behind the symphysis pubis, embedded in the anterior wall of the vagina, and its direction is obliquely downward and forward; it is slightly curved with the concavity directed forward. The proximal 2/3rds is lined by transitional epithelium cells while distal 1/3rd is lined by stratified squamous epithelium cells.[10] The urethra consists of three coats: muscular, erectile, and mucous, the muscular layer being a continuation of that of the bladder. Between the superior and inferior fascia of the urogenital diaphragm, the female urethra is surrounded by the urethral sphincter. Somatic (conscious) innervation of the external urethral sphincter is supplied by the pudendal nerve. ...
Esophagus
Colon. *Ascending colon. *Hepatic flexure. *Transverse colon. *Splenic flexure. *Descending colon. *Sigmoid colon ...
လူ၏ အစာအိမ်နှင့် အူလမ်းကြောင်း - ဝီကီပီးဒီးယား
Hindgut တွင် အူမကြီး၏ Transverse colon နောက်ပိုင်း ၃ ပုံ ၁ ပုံ၊ descending colon, sigmoid colon, rectum, anus (စအို) တို့ ပါဝင် ... ascending colon, transverse colon ၏ ရှေ့ ၃ ပုံ ၂ ပုံ ပါဝင်သည်။ ...
Galápagos tortoise
... s are now thought to have descended from a South American ancestor,[21] while the Indian Ocean tortoises ... todas las tierras que forman las islas del Archipiélago de Colón o Galápagos, Registro Oficial No. 873 (1959) Quito, 20 de ... Günther hypothesized that all the giant tortoises descended from a single ancestral population which spread by sunken land ... while the four southern populations are believed to be descended from a second colonization from the more southerly island of ...
म्हुतु
Colon. ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon. continuous (taenia ...
Night of Champions (2009)
The match centered around Maryse keeping her distance from James before descending to the floor in an attempt to use a can of ... The Colóns, and Rhodes and DiBiase (collectively known as The Legacy).[19] Two weeks following the event on the July 6 episode ...
Flat Earth
... and that thus even the inhabitants of that distant region are descended from that one first man.[82] ...
মুখবিবর - উইকিপিডিয়া
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
Functional constipation
Descending perineum syndrome. *Other inability or unwillingness to control the external anal sphincter, which normally is under ... Deeper psychosomatic disorders which sometimes affect digestion and the absorption of water in the colon ... Firestone Baum, C; John A; Srinivasan K; Harrison P; Kolomensky A; Monagas J; Cocjin J; Hyman PE (January 2013). "Colon ...
Gastrointestinal system
Maragul bituka: Cecum • Colon (ascending colon, transverse colon, descending colon, sigmoid colon) • Rectum (Houston valve, ...
Education in Haiti
Colon, Jorge. "A Call for a Response From The International Chemistry Community. (Science For Haiti)." Chemistry International ... Logan attributed this disparity to racism, even though citizens of both countries were descended from African slaves.[17] The ... Machlis, Gary E, Jorge Colón, and Jean E. McKendry. Science for Haiti: A Report on Advancing Haitian Science and Science ...
Pancreas
In front of the pancreas sits the transverse colon.[4]. The pancreas narrows towards the tail, which sits next to the spleen.[4 ... Surrounded by a muscle, the sphincter of Oddi, this opens into the descending part of the duodenum.[4] ... Behind rests the inferior vena cava, and in front sits the peritoneal membrane and the transverse colon.[4] ... To the right sits the descending part of the duodenum, and between these travel the superior and inferior pancreaticoduodenal ...
Template:Digestive tract
Colon. ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon. continuous (taenia ...
Levator ani
Iliac colon, sigmoid or pelvic colon, and rectum seen from the front, after removal of pubic bones and bladder. ... In the female the anterior fibers of the levator ani descend upon the side of the vagina. ... the anterior fibers descend upon the side of the prostate to unite beneath it with the muscle of the opposite side, joining ...
বৃহদন্ত্র - উইকিপিডিয়া
পরিপাকতন্ত্রের শারীরবৃত্তে কোলন বা বৃহদন্ত্র (বৃহৎ +অন্ত্র) (ইংরেজি: Colon) পরিপাকনালীর সেই অংশ যা মল থেকে পানি নিষ্কাশন করে। ... ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ... Colon Function And Health Information ওয়েব্যাক মেশিনে আর্কাইভকৃত ৫ সেপ্টেম্বর ২০১২ তারিখে Retrieved on 2010-01-21 ...
Psoas major muscle
The nerve then traverses the retroperitoneum, descending over the anterior surface of the psoas.[11] ... Care should be taken around the abdominal organs, especially the colon when palpating deeply. ...
Male reproductive system
A failure in this process can cause indirect inguinal hernia or an infantile hydrocoele.[citation needed]The testes descend ...
Wikipedia:Plain and simple guide for medical editors
Each colon moves the comment farther to the right, so if the person above you used 3 colons (:::) you should use 4 (::::). To ... Roughly in descending order of quality, lower-quality evidence in medical research comes from individual RCTs; other controlled ... To make conversations easier to follow, place your comments below the one you are responding to and indent it using a colon ...
Descending Colon - Anatomy and Physiology
Finally, the outermost anterior layer of the descending colon is visceral peritoneum; on the posterior of the descending colon ... The descending colon is a segment of the large intestine and is the third and penultimate segment of the colon. It transports ... During defecation, the descending colon helps to propel feces toward the sigmoid colon and rectum and eventually out of the ... At its superior end, the descending colon connects to the transverse colon at the splenic flexure just inferior to the spleen. ...
Descending colon Anatomy, Diagram & Function | Body Maps
The colon is part of the large intestine, the final part of the digestive system. Its function is to reabsorb fluids and ... The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon. ... Descending colon. Descending colon. Medically reviewed by the Healthline Medical Network - Written by the Healthline Editorial ... The descending colon stores the food to be emptied into the rectum. The colon is held in place by peritoneum, a thin layer of ...
Descending colon Anatomy, Diagram & Function | Body Maps
The colon is part of the large intestine, the final part of the digestive system. Its function is to reabsorb fluids and ... The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon. ... The descending colon stores the food to be emptied into the rectum. The colon is held in place by peritoneum, a thin layer of ... The descending colon is located on the left side of the large intestine, extending from the bend below the spleen to the ...
What is a Descending Colon? (with pictures)
The descending colon is part of the large intestine that passes along the side of the left kidney. Problems with the descending ... They include the ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, and sigmoid colon. This ... The large intestine includes the vermiform appendix, the cecum and the colon. The descending colon is part of the colon, which ... Colon pain is one of the common descending colon cancer symptoms, but by itself it isnt enough to make a diagnosis. Colon pain ...
Descending colon - Wikipedia
... many casual mentions of the left colon chiefly concern the descending colon. The descending colon begins at the splenic flexure ... Cancer of the descending colon is a serious disease. A person can have colon cancer yet have no symptoms in the early stages. ... The descending colon is on the left side of the body (barring any malformations). The term left colon is hypernymous to ... the descending colon is the part of the large intestine from the splenic flexure to the beginning of the sigmoid colon. The ...
PatientsLikeMe | Descending Colon Resection report for patients like you
Find the most comprehensive real-world treatment information on Descending Colon Resection at PatientsLikeMe. 0 patients with ... bipolar I disorder or psoriasis currently have Descending Colon Resection. ... What is Descending Colon Resection?. Category: Surgeries false A descending colon resection (colectomy) is a type of surgery ... Stopped having Descending Colon Resection Duration. Patients. This item is relevant to you: Less than 1 month 1 * 1 ...
Cell Ontology - descending colon - Classes | NCBO BioPortal
The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending ... The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending ... http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Descending_Colon SYN LOOM ... colon lying in the left iliac fossa is sometimes called the iliac colon. ...
BioModels Ontology - Descending colon - Classes | NCBO BioPortal
ICD-10-PCS Code 0DTM0ZZ - Resection of Descending Colon, Open Approach - Codify by AAPC
ICD-10-PCS code 0DTM0ZZ for Resection of Descending Colon, Open Approach is a medical classification as listed by CMS under ... Resection of Descending Colon, Open Approach 0DTM0ZZ. ICD-10-PCS code 0DTM0ZZ for Resection of Descending Colon, Open Approach ... Descending Colon. Definition: Cutting through the skin or mucous membrane and any other body layers necessary to expose the ...
ICD-10-PCS Code 0D7M4ZZ -Dilation of Descending Colon, Percutaneous Endoscopic Approach- Codify by AAPC
https://www.thefreelibrary.com/A+rare+case+of+Wild-Type+GIST+of+descending+colon+with+GANT...-a0589800473
A rare case of Wild-Type GIST of descending colon with GANT characteristics.(Letter to the editor) by The Turkish Journal of ... colon+with+GANT...-a0589800473. *APA style: A rare case of Wild-Type GIST of descending colon with GANT characteristics.. (n.d ... On endoscopic examination of the colon, a pedunculated mass partially obliterating the lumen of the descending colon was ... MLA style: "A rare case of Wild-Type GIST of descending colon with GANT characteristics.." The Free Library. 2019 AVES 14 Aug. ...
A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral...
A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral ... "AJCC: colon and rectum," in AJCC Cancer Staging Manual, S. B. Edge, D. R. Byrd, C. C. Compton, A. G. Fritz, F. L. Greene, and A ... Report of a case," Diseases of the Colon and Rectum, vol. 26, no. 6, pp. 390-392, 1983. View at Google Scholar · View at Scopus ... J.-Y. Yang, J.-K. Lee, S.-M. Cha, and Y.-B. Joo, "Psoas abscess caused by spontaneous rupture of colon cancer," Clinics in ...
A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral...
Human Colon descending (Normal) tissue lysate | GeneTex
Human Colon descending (Normal) tissue lysate, GTX28698, Applications: ELISA, IP, WB; ELISA, Immunoprecipitation, Western Blot ... Human Colon descending (Normal) lysate, Human Colon descending (Normal) tissue extract. Lysate Fraction. Whole Cell Extract/ ... Human Colon descending (Normal) tissue lysate See all Human Colon lysate products ...
2006 ICD-9-CM Diagnosis Code 863.53 : Injury to descending (left) colon with open wound into cavity
Short description: DESCENDING COLON INJ-OPN.. *ICD-9-CM 863.53 is a billable medical code that can be used to indicate a ... Injury to descending (left) colon with open wound into cavity. * ... colon 863.40. *. with*. open wound into cavity 863.50. *. ... 2015/16 ICD-10-CM S36.502A Unspecified injury of descending [left] colon, initial encounter ...
Congenital Descending Colonic Stenosis with Perforation of Transverse Colon in a Neonate: A Case Report
| Journal of...
Congenital Descending Colonic Stenosis with Perforation of Transverse Colon in a Neonate: A Case Report * R Hamid Senior ... PHOTOGRAPH SHOWING STENOTIC SEGMENT OF DESCENDING COLON * POST OPERATIVE PHOTOGRAPH OF SAME PATIENT WITH END COLOSTOMY WITH ... At the junction of descending and sigmoid colon a stenosis was found, laparotomy also revealed a perforation of transverse ... INTRAOPERATIVE PHOTOGRAPH SHOWING STENOSIS SEGMENT OF DESCENDING COLON * INTRAOPERATIVE PHOTOGRAPH SHOWING STENOTIC SEGMENT OF ...
The descending colon is supplied by the artery, a branch of the artery. left colic inferior mesenteric B. left colic superior...
The descending colon is supplied by the artery, a branch of the _ artery. A. left colic inferior mesenteric B. left colic ... The descending colon is supplied by the _____ artery, a branch of the _____ artery. A.left colic inferior mesenteric B.left ... The descending colon is supplied by the artery, a branch of the _ artery. left colic inferior mesenteric B. left colic superior ...
Proliferative Enteropathy (PE)-Induced Changes in the Calbindin-Immunoreactive (CB-IR) Neurons of Inferior Mesenteric Ganglion...
The retrograde tracer fast blue (FB) was injected into the descending colons of all animals and then tissue comprising IMGs ... neurons projecting to the colon exhibit calbindin-like immunoreactivity. It is not known if there are any changes in the ... Neurons in the ENS of the Porcine Descending Colon. *Krystyna Makowska, Kazimierz Obremski, Lukasz Zielonka, Slawomir Gonkowski ... distribution in intramural nervous structures of the porcine descending colon. *Slawomir Gonkowski, Krystyna Makowska, Jaroslaw ...
2018 ICD-10-CM Diagnosis Code C18.6: Malignant neoplasm of descending colon
Malignant neoplasm of descending colon. 2016 2017 2018 Billable/Specific Code *C18.6 is a billable/specific ICD-10-CM code that ... Primary malignant neoplasm of descending colon. ICD-10-CM C18.6 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0): * ... Malignant neoplasm of colon. 2016 2017 2018 Non-Billable/Non-Specific Code Type 1 Excludes*malignant carcinoid tumors of the ... Cancer of the colon, descending. *Primary adenocarcinoma of descending colon. * ...
Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon<...
Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon. / Browning, ... Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon. ... N2 - Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and ... AB - Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and ...
Descending Colon
Descending Colon | ANATOMIC.US
... transverse colon, splenic flexure, descending colon, and sigmoid colon. The descending colon passes down through the upper back ... The descending colon is a part of the colon, which is made up of several parts. They include the ascending colon, hepatic ... Descending Colon The descending colon of humans passes downward through the left hypochondrium and lumbar regions, along the ... Cancer of the descending colon is the most serious of the diseases. A person can have colon cancer yet have no symptoms in the ...
Ascending, Transverse, Descending Colon
... May 25, 2017 Anatomy The small intestine connects to the colon where a valve regulates ... the descending colon. The colon is responsible for resabsorption of water and collect undigested waste for elimination. The ... As the colon moves towards the head, it is called the ascending colon. It then moves laterally across the abdomen where it is ... The cecum is a pouch-like section of the large intestine that is the first part of the colon, also called the large intestine. ...
Tumor in the descending colon
... GeneralEquipmentPreparationImplementationFollow-up. General. For cancer in the descending colon ... Oncolex - cancer encyclopedia › About cancer in the colon/rectum › Treatment › Surgery colon › Tumor in descending ... Surgery colonTumor in cecum and ascending Tumor in right flexure Tumor in transversumTumor in left flexure Tumor in descending ... The bowel is divided to the left on the transverse colon and upwards on the rectum. The distal sigmoid colon is not being ...
2021 ICD-10-CM Diagnosis Code S36.512: Primary blast injury of descending [left] colon
Primary blast injury of descending [left] colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code *S36.512 should ... Unspecified injury of descending [left] colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code ... Primary blast injury of colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code Applicable To*Blast injury of colon ... Injury of colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code Type 2 Excludes*injury of rectum (S36.6-) ...
Find other content tagged with 'descending colon'
Diagram descending colon - Bowtrol colon cleanser - Nov 27, 2017
Diagram descending colon - Abdomen - Wikipedia, the free encyclopedia. Bowtrol is formulated to maximize ones elimination ... The colon and rectum are parts of the digestive... ascending colon, transverse colon, descending colon, and sigmoid colon... ... CARCINOMA OF THE COLON. STAGING DIAGRAM. SITE: Ascending Colon. Cecum Colon, NOS Descending Colon Hepatic Flexure of Colon. ... The last part of the colon. The distal colon includes the descending colon (the left side of the colon) and the sigmoid colon ( ...
Descending colons | definition of descending colons by Medical dictionary
... descending colons explanation free. What is descending colons? Meaning of descending colons medical term. What does descending ... Looking for online definition of descending colons in the Medical Dictionary? ... descending colon. (redirected from descending colons). Also found in: Dictionary, Thesaurus, Encyclopedia. de·scend·ing co·lon ... Synonym(s): colon descendens [TA]. de·scend·ing co·lon. (dĕ-sending kōlŏn) [TA] The part of the colon extending from the left ...
ICD-10 Code: D12.4 - Benign neoplasm of descending colon
Bowel - large bowel - descending colon - sigmoid Emotions , Personal Development
It is located at the end of the left colon ... The sigmoid is the area of the descending colon (before the ... descending colon - sigmoid. Published on Digestive system.. The sigmoid is the area of the descending colon (before the rectum ... It is located at the end of the left colon or descending colon, followed by the rectum and the anus. ... Cancer of the descending colon is more frequent in the sigmoid and the rectum. ...
SigmoidRectumCecumSplenic flexureResectionBowelColonicAbdomenRectal cancerMalignant neoplasm of desceTumorAnatomyPolypsFecesSpleenColonoscopyLumen of the desceDiagnosisMucousAscending ColonMucosaArterialBiopsiesLeftCancersAdenocarcinomaCrohn'sDiseasesColitisCaecumDigestive systemSegmentProximalSymptomsLargeTissueStomachSurgerySmallStoolMyenteric plexusChemotherapyProblems with the desceTissuesAbdominalTreatment of Colon CancerPatients with colon cancerSurgical
Sigmoid34
- It transports feces from the transverse colon inferiorly along the left side of the abdominal cavity to the sigmoid colon. (innerbody.com)
- From the splenic flexure, the descending colon extends inferiorly toward the left hip before turning about 90 degrees to the right and forming the sigmoid colon. (innerbody.com)
- During defecation, these muscle cells contract in waves of peristalsis to push feces down the colon toward the sigmoid colon. (innerbody.com)
- During defecation, the descending colon helps to propel feces toward the sigmoid colon and rectum and eventually out of the body by contraction of its smooth muscle tissue. (innerbody.com)
- The descending colon is located on the left side of the large intestine, extending from the bend below the spleen to the sigmoid colon. (healthline.com)
- In the anatomy of humans and homologous primates, the descending colon is the part of the large intestine from the splenic flexure to the beginning of the sigmoid colon. (wikipedia.org)
- It passes downward through the left hypochondrium and lumbar regions, along the outer border of the left kidney and ends at the lower left part of the abdomen where it continues as the sigmoid colon. (wikipedia.org)
- Retroperitoneal abscess complicated with necrotizing fasciitis of the thigh in a patient with sigmoid colon cancer," World Journal of Surgical Oncology , vol. 7, article 74, 2009. (hindawi.com)
- C. M. Peterson, J. G. Allison, and C. C. Lu, "Psoas abscess resulting from perforating carcinoma of the sigmoid colon. (hindawi.com)
- At the junction of descending and sigmoid colon a stenosis was found, laparotomy also revealed a perforation of transverse colon. (nepjol.info)
- Transverse colostomy and a mucous fistula of sigmoid colon was performed after resecting stenosing segment and colon distal to perforation site upto stenosing site. (nepjol.info)
- The distal sigmoid colon is not being retained because the blood supply may not remain satisfactory. (oncolex.org)
- The sigmoid is the area of the descending colon (before the rectum) where faeces accumulate prior to being released. (flowsandforms.com)
- Cancer of the descending colon is more frequent in the sigmoid and the rectum. (flowsandforms.com)
- The colon is divided into four main sections--ascending or right colon, transverse colon, descending or left colon, and the sigmoid colon. (livestrong.com)
- The sigmoid colon is considered a part of the left colon. (livestrong.com)
- The colonic contents travel from the small intestine up the ascending colon then along the transverse colon then down the descending colon and sigmoid before entering the rectum. (livestrong.com)
- Though these symptoms may also be seen in cancers in the right colon, they are most often seen in the left because the stool is more solid in the descending and sigmoid colon. (livestrong.com)
- In our body's large intestine , the Descending Colon is the segment of the colon , between the Transverse Colon and the sigmoid colon . (wellnessadvocate.com)
- In our body's colon , the Descending Colon passes downward through the left hypochondrium and lumbar regions, along the lateral border of the left kidney , at the lower end of the kidney it turns medialward toward the lateral border of the psoas muscle, and then descends, in the angle between psoas and quadratus lumborum, to the crest of the ilium, where it ends in the sigmoid colon . (wellnessadvocate.com)
- The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. (colonoscopyandendoscopybilling.com)
- The sigmoid colon is the part of the large intestine after the descending colon and before the rectum. (colonoscopyandendoscopybilling.com)
- The walls of the sigmoid colon are muscular, and contract to increase the pressure inside the colon, causing the stool to move into the rectum. (colonoscopyandendoscopybilling.com)
- The sigmoid colon is supplied with blood from several branches (usually between 2 and 6) of the sigmoid arteries, a branch of the IMA. (colonoscopyandendoscopybilling.com)
- Its four parts are the ascending colon , transverse colon , descending colon and sigmoid colon . (cancerqld.org.au)
- The rectum extends through the pelvis from the end of the sigmoid colon to the anus. (limamemorial.org)
- Colored x-ray of the large intestine of a patient with sigmoid colon cancer after a barium (white) enema. (clinicaladvisor.com)
- What causes erythematous mucosa in the sigmoid colon? (healthtap.com)
- Can mild thickening and fat in wall of large bowel including sigmoid colon and right colon on CT scan be normal? (healthtap.com)
- CECT whole abdomen with rectal contrast shows mild thickening of mucosal folds in sigmoid colon. (healthtap.com)
- Control colon showing no more than mild autolysis was taken at autopsy from 6 patients (aged 2 months to 4 years) in whom there was no evidence of colonic disease, and for each case sections from rectum, sigmoid, and ascending and transverse colon were selected. (thefreelibrary.com)
- The person living with a descending or sigmoid colostomy has the option of managing their colostomy with irrigation. (cancer.org)
- I was sent for a colonoscopy, and a mass was discovered which was determined to be stage 3B cancer of the sigmoid colon. (medicinenet.com)
- The rectum measures six to 12 inches long and is located between the sigmoid colon and the anus . (verywellhealth.com)
Rectum26
- The descending colon stores the food to be emptied into the rectum. (healthline.com)
- The function of the descending colon in the digestive system is to store the remains of digested food that will be emptied into the rectum. (wikipedia.org)
- The bowel is divided to the left on the transverse colon and upwards on the rectum. (oncolex.org)
- It is located at the end of the left colon or descending colon, followed by the rectum and the anus. (flowsandforms.com)
- Impaction of the descending colon was palpated per rectum where gas distention of the ascending colon prevented any further evaluation. (clinicabagnarola.it)
- Colorectal cancer (also known as colon cancer, rectal cancer, or bowel cancer) is the development of cancer in the colon or rectum (parts of the large intestine). (icd.codes)
- Lymphatic drainage from the entire colon and proximal two-thirds of the rectum is to the paraaortic lymph nodes that then drain into the cisterna chyli. (colonoscopyandendoscopybilling.com)
- An operation for rectal cancer, which involves removing part of the colon and the rectum and anus and creating a permanent colostomy. (cancerqld.org.au)
- The large bowel includes the colon and the rectum. (cancerqld.org.au)
- Its four main sections are the caecum, colon , rectum and anus. (cancerqld.org.au)
- Removal of the entire colon and the rectum is called a proctocolectomy. (medlineplus.gov)
- Removal of all of the colon but not the rectum is called subtotal colectomy. (medlineplus.gov)
- Thought you might appreciate this item(s) I saw at Diseases of the Colon & Rectum. (lww.com)
- This is the small "S" shaped part of the colon, about 40 cm in length, which goes from the bottom of the descending colon into the centre of the pelvis to the rectum . (wikipedia.org)
- Forces the stool produced in colon to the rectum. (prezi.com)
- descending colon and rectum. (celiac.com)
- The variant blood supply to the descending colon, rectosigmoid and rectum based on 400 dissections. (lww.com)
- Tumors or cancer of the COLON or the RECTUM or both. (bioportfolio.com)
- Cancer cells within the colon or rectum are called adenocarcinoma. (loyolamedicine.org)
- colon cancer begins specifically in the colon while rectal cancer begins in the rectum. (loyolamedicine.org)
- Colonoscopy , or an examination of the entire rectum and colon using a scoping tool, is the most common method used to identify the presence of cancer cells or tumors in the colon. (loyolamedicine.org)
- In the caudal abdomen the colon curves to the midline and joins the rectum. (thefreedictionary.com)
- In the horse there is the additional oddity of a significant reduction in diameter at the small colon, the terminal part which joins the rectum. (thefreedictionary.com)
- the third and last of the three main divisions of the colon which runs caudally and terminates in the rectum. (thefreedictionary.com)
- The rectum is a part of the colon, and both organs together are called the large intestine. (verywellhealth.com)
- Flare since '12 descending colon to rectum. (healingwell.com)
Cecum9
- The large intestine includes the vermiform appendix , the cecum and the colon. (wisegeek.com)
- The cecum is a pouch-like section of the large intestine that is the first part of the colon, also called the large intestine. (anatomycorner.com)
- It is the part of the colon from the cecum to the hepatic flexure (the turn of the colon by the liver). (colonoscopyandendoscopybilling.com)
- In ruminant grazing animals, the cecum empties into the spiral colon. (colonoscopyandendoscopybilling.com)
- This part of the colon goes from the cecum (where the small intestine ends) up the right hand side of the abdomen . (wikipedia.org)
- wall, large colon, and cecum. (cdc.gov)
- the segment of the colon that extends up the cecum in the lower right side of the colic fissure to the abdomen to the transverse colon at the hepatic flexure on the right side. (thefreedictionary.com)
- There is an ascending colon which begins at the cecum, passes forward to the cranial part of the abdominal cavity then crosses to the left side as the transverse colon. (thefreedictionary.com)
- In the horse the ascending colon forms an uncoiled loop reflexed upon itself, beginning at the cecum as the right ventral colon, passing to the left ventral, to the left dorsal at the pelvic flexure, then to the right dorsal, then back into the standard pattern at the transverse colon. (thefreedictionary.com)
Splenic flexure3
- At its superior end, the descending colon connects to the transverse colon at the splenic flexure just inferior to the spleen. (innerbody.com)
- The descending colon begins at the splenic flexure at the upper left part of the abdomen. (wikipedia.org)
- Computed tomography (CT) scan demonstrated a prestenotic distension of the splenic flexure of the colon with thickening of the bowel wall and an intraluminal multi-lobular formation (Figure 1). (thefreelibrary.com)
Resection26
- What is Descending Colon Resection? (patientslikeme.com)
- A descending colon resection (colectomy) is a type of surgery done to remove all or part of your large bowel (large intestine or colon). (patientslikeme.com)
- There are no evaluations for Descending Colon Resection. (patientslikeme.com)
- ICD-10-PCS code 0DTM0ZZ for Resection of Descending Colon, Open Approach is a medical classification as listed by CMS under Gastrointestinal System range. (aapc.com)
- For cancer in the descending colon, a left-sided hemicolectomy and a standard bowel- and lymph node resection are performed. (oncolex.org)
- Resection and anastomosis of the descending colon in 43 horses. (elsevier.com)
- 6 months) term survival, (2) factors associated with short-term survival, and (3) the perioperative course for horses with resection and anastomosis of the descending colon. (elsevier.com)
- Horses (n=43) that had descending colon resection and anastomosis. (elsevier.com)
- Medical records (January 1995-June 2009) of 7 equine referral hospitals were reviewed for horses that had descending colon resection and anastomosis and were recovered from anesthesia. (elsevier.com)
- Complications include postoperative fever and diarrhea but the prognosis is good after small colon resection and anastomosis. (elsevier.com)
- Colon resection of descending colon. (healthtap.com)
- Over 2 years post low anterir colon resection. (healthtap.com)
- Had lower colon resection and still have pain when "going" after 8 months. (healthtap.com)
- Why is colon resection still done for colon cancer in cases with liver metastasis? (healthtap.com)
- Colon resection from cancer. (healthtap.com)
- I'm having a laparoscopic colon resection surgery on the 25th. (healthtap.com)
- I had a colon resection done by da Vinci on Thursday. (healthtap.com)
- I had a colon resection surgery one year ago diagnosed stage 1 colon cancer. (healthtap.com)
- 3 years after my colon resection. (healthtap.com)
- Can I eat fiber after colon resection? (healthtap.com)
- The recommended standard of care for patients after resection of stage III colon cancer is adjuvant 5FU-based chemotherapy - FOLFOX (fluorouracil, leucovorin with oxaliplatin) - or CAPOX (capecitabine. (bioportfolio.com)
- Baseline computed tomography (CT) of the chest, abdomen, and pelvis with contrast and carcinoembryonic antigen (CEA) are the preferred cost-effective, colon-cancer staging studies done before surgical resection. (nih.gov)
- Surgical resection is the main treatment modality for localized early-stage colon cancer. (nih.gov)
- They had to remove a foot and a half of my small colon (doing a resection), my appendix , one ovary, and part of the large colon. (medicinenet.com)
- Patients with metachronous peritoneal metastasis after curative resection for stage I-III colon cancer were retrospectively reviewed, and the incidence and prognosis of metachronous peritoneal metastasis were investigated. (nih.gov)
- A proportion of colon cancer patients with metachronous peritoneal metastasis may benefit from combined peritoneal nodule resection and systemic chemotherapy. (nih.gov)
Bowel9
- While the first part of the large intestine is responsible for the absorption of water and other substances from the chyme, the main function of the descending colon is to store waste until it can be removed from the body in solid form, when a person has a bowel movement. (wikipedia.org)
- Among the most common are the inflammatory bowel diseases (such as ulcerative colitis or Crohn's disease) and colon cancer. (wikipedia.org)
- Inflammatory bowel diseases (IBD), including Crohn's disease (CD), and ulcerative colitis (UC), are a group of inflammatory conditions related to the colon and small intestines and characterized by chronic inflammation. (frontiersin.org)
- The large bowel is also called the large intestine or colon. (medlineplus.gov)
- Removing the right colon and valve that separates the small bowel from colon sets the stage for bacterial contamination of the small bowel, which leads to diarrhea commonly-can be treated, with good success. (healthtap.com)
- Signs and symptoms of colon cancer are very similar to symptoms of inflammatory bowel disease and other gastrointestinal illnesses. (loyolamedicine.org)
- Bowel inflammation, which often occurs in inflammatory bowel disease , also increases the risk of developing colon cancer. (loyolamedicine.org)
- Irrigation is simply putting water into the colon through the stoma to help regulate bowel movements. (cancer.org)
- There are several factors that increase a person's chance of developing colon cancer, some within a person's control (for example, being overweight and leading a sedentary lifestyle) and some not (for example, having an inflammatory bowel disease). (verywellhealth.com)
Colonic6
- Safety and efficacy of endoscopic colonic stenting as a bridge to surgery in the management of intestinal obstruction due to left colon and rectal cancer: a systematic review and meta-analysis," Surgical Oncology , vol. 22, no. 1, pp. 14-21. (hindawi.com)
- it is concluded that, in addition to their previously described depressant actions on neuro-effector transmission to colonic smooth muscle, pancreatic polypeptides can exert powerful inhibitory effects on myenteric neurones of the descending colon. (elsevier.com)
- Absorption of water and Na + in descending colonic crypts is dependent on the barrier function of the surrounding myofibroblastic pericryptal sheath. (beds.ac.uk)
- Here the effects of high and low Na + diets and exposure to whole body ionising radiation on the growth and activation of the descending colonic pericryptal myofibroblasts are evaluated. (beds.ac.uk)
- These results demonstrate an activation of descending colonic myofibroblasts to trophic stimuli, or irradiation, which can be attenuated by Captopril, indicative of local trophic control by angiotensin II and TGF-β release. (beds.ac.uk)
- It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon. (bioportfolio.com)
Abdomen9
- This part of the colon passes down through the upper back portion of the abdomen and along the side of the left kidney . (wisegeek.com)
- This is part of the left colon lying in the left side of the abdomen. (sussexsurgery.com)
- It then moves laterally across the abdomen where it is called the transverse colon and finally makes the turn to head toward the posterior of the body, the descending colon . (anatomycorner.com)
- The ascending colon, on the right side of the abdomen, is about 25 cm long in humans. (colonoscopyandendoscopybilling.com)
- The portion of colon that begins in the lower right part of the abdomen, departing from the end of the small intestine. (oreilly.com)
- Colored x-ray of the abdomen (frontal) after a double contrast barium enema highlighting cancer of the left descending colon. (clinicaladvisor.com)
- The first segment of the colon, which begins in the right lower quadrant of the abdomen at the caecum and ends at the hepatic (right colic) flexure in the right upper quadrant of abdomen, after which point it becomes the transverse colon. (thefreedictionary.com)
- In the ruminants and the pig this takes the form of a spiral colon of centrifugal and centripetal loops which occupies the right side of the abdomen. (thefreedictionary.com)
- The colon is located around the perimeter of the abdomen and is about five feet in length. (verywellhealth.com)
Rectal cancer3
- In 2012, there will be 103,170 new cases of colon cancer and 40,290 new cases of rectal cancer diagnosed. (clinicaladvisor.com)
- The term "colon cancer" is often blended with the term "rectal cancer" to form the hybrid term colorectal cancer. (loyolamedicine.org)
- The term colon cancer is sometimes used interchangeably with colorectal cancer because colon and rectal cancer share common features. (verywellhealth.com)
Malignant neoplasm of desce1
- C18.6 is a billable ICD code used to specify a diagnosis of malignant neoplasm of descending colon. (icd.codes)
Tumor4
- The ascending colon is wider than its descending counterpart, which allows for more growth of tumor before the tumor causes symptoms. (livestrong.com)
- Colored x-ray of the colon highlighting a large tumor (green area), which is causing the narrowing of the large intestine with possible obstruction. (clinicaladvisor.com)
- This malignant tumor type begins as a benign polyp (abnormal tissue growth from the mucous lining of the colon), hence its reason for removal. (clinicaladvisor.com)
- Sr. Dowling had a tumor in his descending colon and some heart issues. (oneradionetwork.com)
Anatomy4
- The Function Of The Colon Retrieved on 2010-01-21 Lotti M. Anatomy in relation to left colectomy Anatomy figure: 37:06-06 at Human Anatomy Online, SUNY Downstate Medical Center - "The large intestine. (wikipedia.org)
- The Colon (Human Anatomy): Picture, Function, Definition. (drug-purchase.info)
- These symptoms are explained by the anatomy of ascending colon. (livestrong.com)
- The symptoms of left-sided colon cancer are attributed the anatomy of that area of the colon. (livestrong.com)
Polyps5
- What Are the Treatments for Malignant Colon Polyps? (livestrong.com)
- What are the most common polyps found in the colon? (brainscape.com)
- Pendunculated polyps hang off ___ attached to the walls of the colon. (brainscape.com)
- I never would've thought polyps or colon cancer, no family members had it. (medicinenet.com)
- Most colon cancers are caused by growths within the inner lining of the colon, called polyps, that change into cancer over many years. (verywellhealth.com)
Feces8
- Feces passing through the descending colon are stored until they are ready to be eliminated from the body. (innerbody.com)
- The walls of the descending colon absorb water as well as remaining nutrients and vitamins from the feces, depositing these valuable substances into our bloodstream. (innerbody.com)
- It contains many small pouches, known as haustra, along its length that increase its surface area and help to move feces through the colon. (innerbody.com)
- The mucus secreted from goblet cells in the mucosa layer provides lubrication to feces moving through the lumen, protecting the delicate tissues of the colon. (innerbody.com)
- By the time feces reach the descending colon, the vast majority of nutrients, vitamins and water have been extracted by the ascending and transverse colon, leaving mostly waste products. (innerbody.com)
- Still, some absorption of water and vitamins produced by bacterial fermentation of feces - including vitamins K, B1, B2 and B12 - does occur in the descending colon. (innerbody.com)
- Symptoms on the left side of the colon are usually caused by growth outward into the lumen, obstructing the flow of feces. (livestrong.com)
- The colon takes water from the feces that goes through it. (wikipedia.org)
Spleen2
- It goes underneath the stomach and the pancreas and joins the descending colon near the spleen . (wikipedia.org)
- Characteristic findings include a palpable medial displacement of the spleen and the absence of the pelvic flexure of the colon from its usual site in front of the pelvis. (thefreedictionary.com)
Colonoscopy4
- My colonoscopy: the descending colon mucosa is "erythematous, hemorrhagic, ulcerated, and to show loss of vascular markings suggestive of stercoral ulcers due to constipation. (celiac.com)
- In the meantime, for your piece of mind, a home FIT (fecal immunochemical test) can be performed & will pick up 79% of colon cancers with a single screen (the rate is closer to 95% for colonoscopy). (healthtap.com)
- In almost all patients, a diagnostic or screening colonoscopy is required for tissue biopsy pathological confirmation of colon carcinoma. (nih.gov)
- My colon cancer diagnosis was established by colonoscopy biopsy followed by lower gastro intestinal CT with contrast, and confirmed by urgent surgery. (medicinenet.com)
Lumen of the desce1
- On endoscopic examination of the colon, a pedunculated mass partially obliterating the lumen of the descending colon was detected (Figure 2). (thefreelibrary.com)
Diagnosis3
- CopperPipe -- Colon pain is one of the common descending colon cancer symptoms, but by itself it isn't enough to make a diagnosis. (wisegeek.com)
- A displacement of the ascending colon was the most likely diagnosis, based on distention detected by rectal palpation. (clinicabagnarola.it)
- How was the diagnosis of your colon cancer established? (medicinenet.com)
Mucous1
- For example, mucinous adenocarcinoma is one subtype that produces excessive mucous and tends to be found on the right side of the colon. (verywellhealth.com)
Ascending Colon17
- The ascending colon (or right colon) is the beginning part of the colon. (healthline.com)
- The appendicular vein removes oxygen-depleted blood from the appendix, which is located at the bottom of the ascending colon. (healthline.com)
- Abdominal wall and thigh abscess resulting from the penetration of ascending colon cancer," Acta Medica Okayama , vol. 59, no. 6, pp. 281-283, 2005. (hindawi.com)
- As the colon moves towards the head, it is called the ascending colon . (anatomycorner.com)
- Also the tumors that develop in the ascending colon tend to grow along the wall of the colon instead of directly outward into the lumen. (livestrong.com)
- The stool is still in liquid form in the ascending colon. (livestrong.com)
- Abdominal exploration showed a normal small intestine and the ascending colon was in regular position, despite distention. (clinicabagnarola.it)
- The ascending colon is supplied by parasympathetic fibers of the vagus nerve (CN X). (colonoscopyandendoscopybilling.com)
- Arterial supply of the ascending colon comes from the ileocolic artery and right colic artery, both branches of the SMA. (colonoscopyandendoscopybilling.com)
- This part of the colon goes across the from the ascending colon. (wikipedia.org)
- The right colon (the ascending colon plus half the transverse colon) mainly enables absorption of water. (ikonet.com)
- In herbivores and omnivores there is a variation on this general plan in that the ascending colon is greatly lengthened. (thefreedictionary.com)
- arterial supply to the ascending colon is provided by the ielocolic and the ____ _____ artery. (sporcle.com)
- the nerves to the ascending colon are derived from the _____ _____ plexus. (sporcle.com)
- I had 12 inches of my ascending colon remover laparoscopically. (medicinenet.com)
- Ascending colon, lamb 51481, day 4 p.i. (asm.org)
- This space is defined by: The ascending colon and caecum laterally (further right). (wikipedia.org)
Mucosa2
- The mucosa forms the innermost layer that surrounds the lumen and is in contact with fecal matter stored in the colon. (innerbody.com)
- Ulcerative colitis can affect any part of the colon (and other mucosa, such as the mouth), but when it affects the descending colon, it is called left-sided colitis. (wikipedia.org)
Arterial2
- During distensions of the colon, arterial blood pressure and heart rate were kept constant by the withdrawal of blood and pacing of the heart, respectively. (elsevier.com)
- Arterial supply to the colon comes from branches of the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). (colonoscopyandendoscopybilling.com)
Biopsies4
- L , descending-colon biopsies. (aacrjournals.org)
- Multidimensional scaling of ascending- and descending-colon biopsies from HNPCC and non-HNPCC patients. (aacrjournals.org)
- Sixty-eight ascending ( filled oval ) and descending ( open oval ) colon biopsies were clustered according to expression of 1336 genes. (aacrjournals.org)
- Multidimensional scaling of ascending and descending fetal colon biopsies. (aacrjournals.org)
Left9
- The descending colon is on the left side of the body (barring any malformations). (wikipedia.org)
- many casual mentions of the left colon chiefly concern the descending colon. (wikipedia.org)
- Ulcerative colitis can affect any part of the colon, but when it affects the descending colon, it is called left-sided colitis. (wisegeek.com)
- the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon. (bioontology.org)
- A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral Obturator Muscle," Case Reports in Surgery , vol. 2014, Article ID 128506, 5 pages, 2014. (hindawi.com)
- Cancer in the transverse colon has a mixture of the symptoms experienced in right and left colon due to the semi-solid nature of stool in this segment. (livestrong.com)
- The left side of the colon . (cancerqld.org.au)
- forward displacement of the left dorsal colon is an uncommon cause of moderate colic in the horse. (thefreedictionary.com)
- The descending colon laterally (further left). (wikipedia.org)
Cancers4
- Colon cancer, like all cancers, is associated with a great tension that the person experienced and did not verbalize, kept well hidden. (flowsandforms.com)
- Cancers in this part of the colon tend to go unnoticed for a long time. (livestrong.com)
- In most cases of colon or rectal cancers, the cause or causes are unknown. (limamemorial.org)
- Based on the tissues involved, colon cancers be further broken down into various types. (verywellhealth.com)
Adenocarcinoma3
- A case of mucinous adenocarcinoma of the colon presenting with psoas abscess," The Korean Journal of Gastroenterology , vol. 52, no. 2, pp. 120-123, 2008. (hindawi.com)
- Histology section of the colon under a light microscope confirming an adenocarcinoma, which developed from the glandular epithelial tissue of the colon. (clinicaladvisor.com)
- Adenocarcinoma is the most common type of colon cancer, accounting for approximately 96 percent of diagnoses. (verywellhealth.com)
Crohn's3
- Among the most common are ulcerative colitis , Crohn's disease, and colon cancer. (wisegeek.com)
- Colon pain can also be a sign of other colon diseases, like Crohn's disease or IBS, so you should have your doctor check it out regardless. (wisegeek.com)
- [1] It is possible to have medical problems with the descending colon including ulcers , cancer and Crohn's disease . (wikipedia.org)
Diseases4
- There are several diseases associated with the descending colon. (wikipedia.org)
- It is important to maintain good colon health, as there are several diseases associated with the descending colon. (wisegeek.com)
- Maintaining good colon health is important because several diseases may negatively impact its function. (wisegeek.com)
- Cancer of this portion of the colon is the most serious of the diseases. (wisegeek.com)
Colitis2
- Abdominal pain may be a symptom of ulcerative colitis, a disease that is associated with the descending colon. (wisegeek.com)
- In a 21-day study, we investigated the effects of AIEC strain UM146 inoculation on microbiota profile of the ileal, cecal, ascending and descending colon in a pig model of experimental colitis. (frontiersin.org)
Caecum1
- The levels of Angiotensin II type 1 receptor (AT1), ACE, collagen type IV, transforming growth factor-β type 1 receptor (TGF-βR1), OB cadherin and α-smooth muscle actin in both descending colon and caecum were evaluated, using immunocytochemistry and confocal microscopy, in rats fed on high and low Na + diets (LS). (beds.ac.uk)
Digestive system4
- The colon is part of the large intestine, the final part of the digestive system. (healthline.com)
- File:Digestive system diagram en.svg - Wikipedia, the free. (drug-purchase.info)
- Your colon, also known as the large intestine, is part of your digestive system. (icdlist.com)
- Colon cancer occurs with the presence of cancer cells in the colon or large intestine of the digestive system. (loyolamedicine.org)
Segment3
- The descending colon is a segment of the large intestine and is the third and penultimate segment of the colon. (innerbody.com)
- The obstructed segment of the colon becomes markedly swollen and does not function as it should. (livestrong.com)
- Second segment of the colon (middle section of the large intestine). (ikonet.com)
Proximal2
- The proximal two-thirds of the transverse colon is perfused by the middle colic artery, a branch of superior mesenteric artery, while the latter third is supplied by branches of the inferior mesenteric artery. (colonoscopyandendoscopybilling.com)
- The proximal colon differs from the distal colon in that it does not have amiloride-sensitive Na + conductance channels [ 4 ]. (beds.ac.uk)
Symptoms7
- A person can have colon cancer yet have no symptoms in the early stages. (wikipedia.org)
- The symptoms of colon cancer vary according to location of the cancer within the colon as well as any spread outside the colon. (livestrong.com)
- The lumen of the colon is smaller than that of its counterpart on the right and therefore the symptoms experienced are due to obstruction of the lumen. (livestrong.com)
- It is important to monitor your digestive health and consult with your doctor if you experience a combination of any signs or symptoms of colon cancer. (loyolamedicine.org)
- There are many potential symptoms of colon cancer , and what symptoms a person experiences depends on factors like the location and size of the cancer. (verywellhealth.com)
- Keep in mind that some people experience no symptoms in the early stages of colon cancer. (verywellhealth.com)
- What Are the Symptoms of Colon Cancer? (verywellhealth.com)
Large3
- Undigested material, such as plant fiber, is passed next to the large intestine, or colon, mostly in liquid form. (limamemorial.org)
- Your colon makes up the first five to six feet of your large intestine, thus making your colon the longest part of your large intestine. (loyolamedicine.org)
- The colon is another term for the large intestine. (healthtap.com)
Tissue6
- Like all parts of the gastrointestinal tract, the descending colon consists of four major tissue layers surrounding a hollow lumen. (innerbody.com)
- on the posterior of the descending colon, the outermost layer is areolar connective tissue (known as adventitia). (innerbody.com)
- The colon is held in place by peritoneum, a thin layer of tissue that supports the abdominal organs. (healthline.com)
- The transverse colon hangs off the stomach, attached to it by a wide band of tissue called the greater omentum. (colonoscopyandendoscopybilling.com)
- 0DUM87Z is a billable procedure code used to specify the performance of supplement descending colon with autologous tissue substitute, via natural or artificial opening endoscopic. (icdlist.com)
- What that means is there may be evidence of inflamed tissue when the wall of the colon is measured but a normal colon is sometimes the same thickness. (healthtap.com)
Stomach2
- The horse was treated with mineral oil (2lt) by stomach tube for two days to soften the feaces in the stenotic small colon. (clinicabagnarola.it)
- The temporary or permanent channeling of the remaining open end of colon through the stomach wall and skin, where an ostomy appliance will attach to capture waste. (oreilly.com)
Surgery4
- What I've always wondered is how somebody can go on with their life as normal after colon cancer surgery. (wisegeek.com)
- We suspected a previous surgery characterized by extensive manipulation of the descending colon. (clinicabagnarola.it)
- Colon cancer surgery at Loyola University Medical Center is rated as a high-performing speciality by U.S. News & World Report's on the 2020-21 Best Hospitals list. (loyolamedicine.org)
- After surgery and lab test her colon cancer spread to her cervix. (medicinenet.com)
Small7
- The small intestine connects to the colon where a valve regulates the movement of food. (anatomycorner.com)
- The most common cause of small colon incarceration was strangulating lipoma. (elsevier.com)
- The colon is wider than the small intestine but only about 6 feet long. (limamemorial.org)
- is the first part of the colon after the small intestine. (limamemorial.org)
- The examination of the entire length of the colon, up to its juncture with the small intestine, using a flexible tube that has a camera and a light source attached. (oreilly.com)
- It is not extensive in the horse, in which it has an unusually long mesentery and is known as the small colon. (thefreedictionary.com)
- It took the doctors and the hospital 3 months to figure out I didn't have gastritis , but stage 4 small colon cancer . (medicinenet.com)
Stool1
- Other imaging techniques used to test or diagnose colon cancer include specialized stool tests, magnetic resonance imaging (MRI) , computed tomography (CT or CAT) scans , tiny cameras implanted in swallowable pills (capsule endoscopy), and positron emission tomography (PET) or PET-CT scans. (loyolamedicine.org)
Myenteric plexus2
- Co-localisation of cocaine- and amphetamine-regulated transcript peptide and vasoactive intestinal polypeptide in the myenteric plexus of the porcine transverse colon. (semanticscholar.org)
- We studied the effects of a severely hypoproteic diet on the quantitative aspects of the myenteric plexus of the descending colon of young rats . (bvsalud.org)
Chemotherapy4
- Sadly, Tony Snow's death was no different, and his body was not even room temperature before the "alternative" medicine anti-chemotherapy ghouls were given voice at Mike Adam's repository of pseudoscientific lies and misinformation in an article entitled Tony Snow Dies Following Chemotherapy for Colon Cancer (opinion) , written by the lying webmaster of craziness himself, Mike Adams. (scienceblogs.com)
- Now, former White House press secretary Tony Snow has died at the young age of 53 following chemotherapy treatment for colon cancer. (scienceblogs.com)
- For reasons we will never know, Tony Snow chose the chemotherapy route in an attempt to treat his colon cancer, subjecting his body to systemic poisons that all the evidence shows produce absolutely no improvement in the five-year survival rate of colon cancer patients. (scienceblogs.com)
- Recurrence and Cancer-Specific Death After Adjuvant Chemotherapy for Stage III Colon Cancer. (bioportfolio.com)
Problems with the desce1
- An ultrasound may be used to detect problems with the descending colon. (wisegeek.com)
Tissues2
- Colon cancer is a disease in which malignant (cancer) cells form in the tissues of the colon.1. (drug-purchase.info)
- The main difference between the response of myofibroblasts in descending colon pericryptal sheath from other tissues is the significant barrier to diffusion of macromolecules and NaCI in the colon generated by the fibronexus i.e. the multiple connections between cells and extracellular matrix [ 1 , 2 ]. (beds.ac.uk)
Abdominal5
- After flushing of the descending colon and abdominal cavity, the abdominal wall was sutured in two layers (fascia and skin) and the horse was put in the recovery box. (clinicabagnarola.it)
- The location of the parts of the colon are either in the abdominal cavity or behind it in the retroperitoneum. (colonoscopyandendoscopybilling.com)
- On the posterior side, the transverse colon is connected to the posterior abdominal wall by a mesentery known as the transverse mesocolon. (colonoscopyandendoscopybilling.com)
- The paramesenteric gutters (paramesenteric recesses or infracolic spaces) are two spaces (or recesses) in the abdominal cavity between the colon and the root of the mesentery. (wikipedia.org)
- Paracolic gutters are recesses between the abdominal wall and the colon. (wikipedia.org)
Treatment of Colon Cancer1
- This activity outlines the etiology, epidemiology, clinical staging and stage-wise treatment of colon cancer. (nih.gov)
Patients with colon cancer2
Surgical3
- We speculated that the most likely condition needing laparotomy and manipulation of the descending colon was the surgical menagement of meconium impaction in the newborn foal. (clinicabagnarola.it)
- Surgical removal of the displaced colon from its entrapment across the top of the gastrosplenic ligament is the only effective treatment. (thefreedictionary.com)
- Palliative systemic therapy is reserved for non-surgical colon cancer candidates aiming to improve quality of life and prolong life expectancy. (nih.gov)