Tumors or cancer of the COLON.
The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.
A segment of the COLON between the RECTUM and the descending colon.
The segment of LARGE INTESTINE between the CECUM and the TRANSVERSE COLON. It passes cephalad from the cecum to the caudal surface of the right lobe of the LIVER where it bends sharply to the left, forming the right colic flexure.
The segment of LARGE INTESTINE between ASCENDING COLON and DESCENDING COLON. It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon.
Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS.
A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.
A pouch or sac opening from the COLON.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
A malignant epithelial tumor with a glandular organization.
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
A cell line derived from cultured tumor cells.
Hydrazines substituted with two methyl groups in any position.
Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)
Endoscopic examination, therapy or surgery of the luminal surface of the colon.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
A benign epithelial tumor with a glandular organization.
Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.
Tumors or cancer of the SIGMOID COLON.
Tumors or cancer of the RECTUM.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
The motor activity of the GASTROINTESTINAL TRACT.
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.
Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.
Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.
A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
The surgical construction of an opening between the colon and the surface of the body.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
Tumors or cancer of the CECUM.
Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.
Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Experimental transplantation of neoplasms in laboratory animals for research purposes.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.
A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.
High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.
The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
A reagent that is used to neutralize peptide terminal amino groups.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Agents that are used to stimulate evacuation of the bowels.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Transplantation between animals of different species.
Tumors or cancer of the INTESTINES.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.
Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Regular course of eating and drinking adopted by a person or animal.
A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Elements of limited time intervals, contributing to particular results or situations.
The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Hydrazines substituted by one or more methyl groups in any position.
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)
A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.
Opening or penetration through the wall of the INTESTINES.
A plastic operation on the esophagus. (Dorland, 28th ed)
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).
Dilatation of the COLON, often to alarming dimensions. There are various types of megacolon including congenital megacolon in HIRSCHSPRUNG DISEASE, idiopathic megacolon in CONSTIPATION, and TOXIC MEGACOLON.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)
DNA present in neoplastic tissue.
In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Tumors or cancer of the LIVER.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Uptake of substances through the lining of the INTESTINES.
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.
Endoscopic examination, therapy or surgery of the sigmoid flexure.
The contents included in all or any segment of the GASTROINTESTINAL TRACT.
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Short-chain fatty acids of up to six carbon atoms in length. They are the major end products of microbial fermentation in the ruminant digestive tract and have also been implicated in the causation of neurological diseases in humans.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.
Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
Antibodies produced by a single clone of cells.
The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Established cell cultures that have the potential to propagate indefinitely.
An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Antimetabolites that are useful in cancer chemotherapy.
Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
The normal process of elimination of fecal material from the RECTUM.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
Specially designed endoscopes for visualizing the interior surface of the colon.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
RNA present in neoplastic tissue.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Organic compounds which contain platinum as an integral part of the molecule.
An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
The action of a drug in promoting or enhancing the effectiveness of another drug.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.
Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)
A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).
A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)
A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).
A subcategory of mucins that contain SIALIC ACID.
Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.
Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.
A rod-shaped, gram-positive, non-acid-fast, non-spore-forming, non-motile bacterium that is a genus of the family Bifidobacteriaceae, order Bifidobacteriales, class ACTINOBACTERIA. It inhabits the intestines and feces of humans as well as the human vagina.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
The combination of two or more different factors in the production of cancer.
Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.
Tumors or cancer of the LUNG.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

A smooth muscle tone-dependent stretch-activated migrating motor pattern in isolated guinea-pig distal colon. (1/35)

We have investigated the tone dependence of the intrinsic nervous activity generated by localized wall distension in isolated segments of guinea-pig distal colon using mechanical recordings and video imaging of wall movements. A segment of colon was threaded through two partitions, which divided the colon for pharmacological purposes into oral, stimulation and anal regions. An intraluminal balloon was located in the stimulation region between the two partitions (12 mm apart). Maintained colonic distension by an intraluminal balloon or an artificial faecal pellet held at a fixed location generated rhythmic (frequency 0.3 contractions min(-1); duration approximately 60 s) peristaltic waves of contraction. Video imaging of colonic wall movements or the selective application of pharmacological agents suggested that peristaltic waves originated just oral (< or = 4 mm) to the pellet and propagated both orally (approximately 11 mm s(-1)) and anally (approximately 1 mm s(-1)). Also, during a peristaltic wave the colon appears to passively shorten in front of a pellet, as a result of an active contraction of the longitudinal muscle oral to the pellet. Faecal pellet movement only occurred when a rhythmic peristaltic wave was generated. Rhythmic peristaltic waves were abolished in all regions by the smooth muscle relaxants isoproterenol (1 microM), nicardipine (1 microM) or papavarine (10 microM), and by the neural antagonists tetrodotoxin (TTX; 0.6 microM), hexamethonium (100 microM) or atropine (1 microM), when added selectively to the stimulation region. Nicardipine, atropine, TTX, or hexamethonium (100 microM) also blocked the evoked peristaltic waves when selectively added to the oral region. Nomega-nitro-L-arginine (L-NA; 100 microM) added to the anal region reduced the anal relaxation but increased the anal contraction, leading to an increase in the apparent conduction velocity of each peristaltic wave. In conclusion, maintained distension by a fixed artificial pellet generates propulsive, rhythmic peristaltic waves, whose enteric neural activity is critically dependent upon smooth muscle tone. These peristaltic waves usually originate just oral to the pellet, and their apparent conduction velocity is generated by activation of descending inhibitory nerve pathways.  (+info)

Distinguishing right from left colon by the pattern of gene expression. (2/35)

Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis. These differences may reflect distinct biological characteristics of proximal and distal colonic mucosa, acquired in embryonic or postnatal development, that determine a differential response to uniformly distributed environmental factors. Alternatively, the differences in the epidemiology of proximal and distal CRCs could result from the presence of different procarcinogenic factors in the ascending versus descending colon, acting on cells with either similar or distinct biological characteristics. We applied cDNA microarray technology to explore the possibility that mucosal epithelium from adult proximal and distal colon can be distinguished by their pattern of gene expression. In addition, gene expression was studied in fetal (17-24 weeks gestation) proximal and distal colon. More than 1000 genes were expressed differentially in adult ascending versus descending colon, with 165 genes showing >2-fold and 49 genes showing >3-fold differences in expression. With almost complete concordance, biopsies of adult colonic epithelium can be correctly classified as proximal or distal by gene expression profile. Only 87 genes were expressed differently in ascending and descending fetal colon, indicating that, although anatomically relevant differences are already established in embryonic colon, additional changes in gene expression occur in postnatal development.  (+info)

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/35)

1. Mechanisms involved in Ca(2+) sensitization of contractile elements induced by the activation of muscarinic receptors in membrane-permeabilized preparations of the rat proximal and distal colon were studied. 2. In alpha-toxin-permeabilized preparations from the rat proximal and distal colon, Ca(2+) induced a rapid phasic and subsequent tonic component. After Ca(2+)-induced contraction reached a plateau, guanosine 5'-triphosphate (GTP) and carbachol (CCh) in the presence of GTP further contracted preparations of both the proximal and distal colon (Ca(2+) sensitization). Y-27632, a rho-kinase inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization more significantly in the proximal colon than in the distal colon. 3. Y-27632 at 10 microm had no effect on Ca(2+)-induced contraction or slightly inhibited phorbol-12,13-dibutyrate-induced Ca(2+) sensitization in either proximal or distal colon. Chelerythrine, a protein kinase C inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization in the distal colon, but not in the proximal colon. The component of Ca(2+) sensitization that persisted after the chelerythrine treatment was completely inhibited by Y-27632. 4. In beta-escin-permeabilized preparations of the proximal colon, C3 exoenzyme completely inhibited GTP plus CCh-induced Ca(2+) sensitization, but PKC(19-31) did not. In the distal colon, C3 exoenzyme abolished GTP-induced Ca(2+) sensitization. It inhibited CCh-induced sensitization by 50 % and the remaining component was inhibited by PKC(19-31). 5. These results suggest that both protein kinase C and rho pathways in parallel mediate the Ca(2+) sensitization coupled to activation of muscarinic receptors in the rat distal colon, whereas the rho pathway alone mediates this action in the proximal colon.  (+info)

Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/35)

BACKGROUND: Because of their suggested link with microsatellite instability high colorectal cancers, right sided hyperplastic polyps (HPs) may differ from their distally located counterparts. This is highlighted by the recognition of a variant HP, termed sessile serrated adenoma (SSA), which predominates in the proximal colon. HPs displaying the morphological features now associated with SSAs have been shown to have altered expression of "cancer associated" markers, but no studies have investigated whether this is dependent on anatomical location of the polyps. AIMS: To evaluate morphological and functional features in right versus left sided HPs from patients without colorectal cancer with the aim of identifying distinguishing characteristics. METHODS: HPs originating in the proximal and distal colorectum were histochemically and immunohistochemically stained to evaluate a panel of markers related to proliferation and differentiation. In addition, a series of morphological features was evaluated for each polyp. RESULTS: Crypt serration, crypt dilatation, and horizontal crypt growth were more common among HPs from the right side, whereas histochemical factors including mucin changes, global methylation status, and expression of carcinoembryonic antigen were not significantly different. An age disparity was also seen between patients with right versus left sided lesions, with patients with right sided lesions being an average of more than 10 years younger than those with left sided lesions. CONCLUSIONS: These findings suggest that right and left sided HPs differ mainly in terms of growth regulation rather than cellular differentiation, implying that these lesions belong to a continuous spectrum of serrated polyps that differ quantitatively rather than qualitatively.  (+info)

Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy. (5/35)

AIM: To review the risk of proximal colon cancer in patients undergoing colonoscopy. METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination). Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma). The sites of neoplasms were defined as rectosigmoid (rectum and sigmoid colon) and proximal colon (from cecum to descending colon). RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings. Among the 157 patients with proximal colon cancer, 74% had no neoplasm in the rectosigmoid colon. Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer. CONCLUSION: Sigmoidoscopy is inadequate for colorectal cancer screening, especially in older populations.  (+info)

Withdrawing method of the stiffening tube incidentally inserted into the descending colon. (6/35)

We experienced a very rare complication of colonoscopy, a migration of stiffening tube into the colorectum. We herein introduce a withdrawing method of migrating stiffening tube incidentally inserted into the colorectum. A 65-year-old Japanese woman underwent colonoscopy because of abdominal discomfort. We used stiffening tube to insert the scope to the proximal colon because of her redundant sigmoid colon. When withdrawing the scope, we realized that the tube was fully inside the colorectum. We could not remove the tube instantly, and it reached the splenic flexure, finally. We reinserted the scope through the migrating tube, straightened the scope, and withdrew it holding a slight angle of the scope over the proximal end of the tube. Then, we could safely remove the tube along with the scope through the anus.  (+info)

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (7/35)

BACKGROUND: Despite the fact that the alimentary tract is part of the body's first line of defense against orally ingested xenobiotica, little is known about the distribution and expression of cytochrome P450 (CYP) enzymes in human colon. Therefore, expression and protein levels of four representative CYPs (CYP2C(8), CYP2E1, CYP3A4, and CYP3A5) were determined in human colon mucosa biopsies obtained from ascending, descending and sigmoid colon. METHODS: Expression of CYP2C, CYP2E1, CYP3A4, and CYP3A5 mRNA in colon mucosa was determined by RT-PCR. Protein concentration of CYPs was determined using Western blot methods. RESULTS: Extensive interindividual variability was found for the expression of most of the genes. However, expression of CYP2C mRNA levels were significantly higher in the ascending colon than in the sigmoid colon. In contrast, mRNA levels of CYP2E1 and CYP3A5 were significantly lower in the ascending colon in comparison to the descending and sigmoid colon. In sigmoid colon protein levels of CYP2C8 were significantly higher by ~73% than in the descending colon. In contrast, protein concentration of CYP2E1 was significantly lower by ~81% in the sigmoid colon in comparison to the descending colon. CONCLUSION: The current data suggest that the expression of CYP2C, CYP2E1, and CYP3A5 varies in different parts of the colon.  (+info)

Comparative study of descendent colon rupture resistance considering traction force of rupture and total energy of rupture in rats. (8/35)

PURPOSE: To compare total energy of rupture and traction force of rupture tests within a rupture resistance study of descendent colon of rats. METHODS: Twelve descendent colon segments of rats were considered to perform the study. For each one of the specimens, total energy of rupture and traction force of rupture necessary to promote colic wall burst were evaluated through the biomechanical total energy of rupture test using the Biomechanical Data Acquisition and Analysis System, version 2.0. Average, standard deviation, standard error of average and coefficient of variation were considered for analysis of results. RESULTS: Traction force of rupture average, standard deviation, standard error of average and coefficient of variation were 380.05 gf, 98.74, 28.5 e 25.98%, respectively while total energy of rupture presented average of 244.85 gf, standard deviation of 57.76, standard error of average of 16.67 and coefficient of variation of 23.59. CONCLUSION: Although, total energy of rupture considered a larger number of attributes to its calculation related to non-linear viscoelastic materials, such as colic wall, it presented a smaller coefficient of variation when compared to traction force of rupture, thus demonstrating to constitute a possible parameter to analyze intestinal resistance of rats.  (+info)

A patient with abdominal discomfort, weight loss, and general weakness was discovered by way of ultrasound and computed tomography to have a tumor in the lower pole of the left kidney. At a second computed tomography examination, the mass had shrunken and air-fluid levels and contrast medium from previous examinations were evident, confirming a renocolic fistula. The patient underwent en bloc left radical nephrectomy with resection of the descending colon. Renal cell carcinoma was confirmed histologically. The patient has been free of disease for 4 years. Such fistulas are usually related to renal calculi or tuberculosis but, of late, more have been the result of iatrogenic trauma sustained during percutaneous renal procedures and lithotripsy. Use of computed tomography and other imaging methods should enable early detection of most renocolic fistulas, which usually are a late manifestation of advanced renal disease. ...
An EVAR often requires multiple wires and catheters be transferred into the vessel via an introducer sheath, which can lead to blood loss through the sheath valve. The sheaths exclusive DrySeal valve is designed to minimise blood loss, enabling the introduction of multiple devices with haemostasis control.. Nearly a third of patients being considered for EVAR have an aneurysm that extends to the iliac artery. The Excluder device is a trusted solution in such cases, but previously no introducer sheaths designed for use with this device existed, said Marcus Brooks, consultant vascular surgeon, North Bristol NHS Trust, UK. With the Gore DrySeal Flex introducer sheath, I now have a sheath specifically designed for use with the iliac branch endoprosthesis and flexible enough for easy access to the iliac branch vessels.. The new sheath leverages technology from Gores DrySeal Sheath, which features a hydrophilic coating for improved access into vessels. In addition, the DrySeal sheath offers an ...
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The present embodiments provide an introducer sheath having a braided member and methods of manufacture. The introducer sheath comprises an inner tube, a braided member disposed over at least a portion of the inner tube, and an outer tube disposed over the inner tube and the braided member. In one embodiment, the braided member comprises a plurality of intersecting first and second wire segments at least partially covered with a coating. At least a portion of the first and second wire segments are bonded together at one or more intersections, for example, by melting the coating, to reduce movement of at least one of the first and second wire segments with respect to one another. Optionally, a coiled member having a plurality of turns may be disposed over a portion of the braided member and the inner tube.
An introducer sheath (10) is provided for percutaneous insertion of catheters into a blood vessel. The introduction of the sheath (10) through a wall of blood vessel causes an opening to be formed thr
Designed for easy insertion and for patient comfort, Input® Introducer Sheaths are offered in two brands - Input TS and Input PS.
INTRODUCTION: There are several alternatives for one-stage emergency treatment of obstructive left-sided colonic cancer (OLCC): subtotal colectomy, intraoperative colon lavage (IOCL) with primary anastomosis, and the placement of a stent as a temporary measure prior to scheduled surgery. At present, it is not clear whether emergency perioperative lavage or the placement of a stent is the better technique. The hypothesis is that IOCL and primary anastomosis is equal safe or even safer than placement of a stent as a temporary measure prior to scheduled surgery, less length of stay and less cost.. OBJECTIVE: To establish which of these two techniques is more efficient in OLCC from the point of view of morbimortality, economic cost, and long-term survival.. MATERIAL AND METHODS:. Prospective, controlled, randomized study of patients diagnosed with OLCC. Patients were divided into two groups: group 1: stent and deferred surgery; group 2: emergency IOCL. A simple randomization system was used. The ...
A method of indicating divergent product benefits by formulating a hand dishwashing liquid having a cleaning agent and a hand care agent; choosing a sensory element profile comprising one or more soft colors and a pearlescent appearance; and incorporating the sensory element profile into the hand dishwashing liquid, such that the sensory element profile indicates the efficacy of the cleaning agent and the efficacy of the hand care agent.
A prospective, randomized, controlled multi-center clinical trial designed to evaluate the safety and effectiveness of the study device in sealing multiple femoral venous access sites and providing reduced times to ambulation compared with manual compression at the completion of catheter-based procedures performed through 6 - 12 Fr introducer sheaths.. Only patients with multiple access sites will be enrolled in order to support the desired indication. Randomization will be stratified to account for patients with varying numbers of access sites in a 1:1 treatment device to control arm ratio to ensure treatment and control arms have the same proportion of access sites/patient, i.e. 3 access sites/patient vs. 4 access sites/patient. ...
Introducers are intended to be inserted percutaneously into a vessel to facilitate the entire interventional procedure. A platinum/iridium band incorporate
box]. Cut the TP rolls into halves and the kitchen rolls into thirds to make smaller rolls. Decorate them with stickers. You could ask your older child to decorate the rolls for you. Sticking and peeling will be a fun fine motor activity for your older child. Your baby might have fun peeling off though and that again was ok since Id see that as a fine motor activity as well. My preschooler was very excited to decorate the paper rolls with stickers and painters. Using tape for holding the cards turned out great since it gave the paper rolls an additional sensory element while playing. You can use any safe sensory element to add to the roll to make playing for baby more exciting.. ...
A method for hemostasis of an artery having a puncture after arterial catheterization, the catheterization using an introducer sheath, the method including the steps of inserting a catheter with a first balloon into the introducer sheath, positioning the first balloon against an outside surface of a wall of the artery at the puncture, inflating the first balloon against the outside surface of the artery at the puncture, and maintaining the first balloon against the puncture so that the first balloon substantially seals blood flow from the puncture so as to achieve hemostasis.
Kayleigh Risser, RA, Reza Gamagami, MD. Silver Cross Hospital. Background: With increasing adoption of laparoscopy for the treatment of colorectal neoplasms, accurate preoperative localization is crucial as most tumors are invisible intraoperatively. There is usually no tactile feedback to assess the presence of a neoplasm. Furthermore, for rectal and rectosigmoid neoplasms, an accurate distance from anal verge will impact whether a patient will receive a colorectal anastomosis versus a coloanal anastomosis with a diversion. The aim of this study was to determine if there was a significant difference between the location of the left-sided colonic neoplasm described by the gastroenterologist as compared to the one performed by the operating surgeon prior to surgery.. Patients and Methods: A single surgeon retrospective analysis of patients referred for left-sided colonic neoplasm (n=85) for laparoscopic surgery from May 2012 to August 2018 was evaluated. Assessed data included: rectal vs. ...
To define the characteristics of colorectal cancer with regard to site distribution, age, and sex, due to the significantly increased incidence of colorectal cancer in Japan, we investigated 1,205 Japanese patients with colorectal cancer between 1975 and 1994. When we compared site distribution for age and sex in the entire 20-year period,...
A holding device and method of use with a peelable or otherwise splittable introducer sheath or catheter through which a cardiac pacing lead or other elongated flexible instrument extends into the body of a living being. The introducer is arranged to be grasped by a user to pull the introducer in the proximal direction so that can be withdrawn out of the beings body. The holding device comprises a first or
6 Mil Blue Vinyl Tape is a highly durable UV-treated poly-vinyl tape that stays in place for up to 6 months yet removes easily without leaving residue. This industrial vinyl tape protects surfaces providing good abrasion, impact and rupture resistance.
A vascular clip includes a peripheral body defining a plane, and tines extending from the body transversely with respect to the plane, the tines biased towards a planar configuration. The clip includes expandable elements disposed along its periphery that are biased to expand from compressed to expanded states for increasing a diameter of the clip upon deployment. The clip is provided within a housing slidably mounted on an introducer sheath. The sheath is introduced through a puncture into a blood vessel, and after a procedure is performed via the sheath, the housing is advanced into the puncture and the clip deployed until the tines engage tissue adjacent the opening in the vessel wall. The sheath is withdrawn from the patient, leaving the clip in place. The tines at least partially move towards the planar configuration to pull the engaged tissue together and close the opening.
Generally cardiac. Cancers are very rare and the possibility of being benign is present ..but after the biopsy will be taken..even if it is cancerous and its growth rate is not high..it can be treated with targeted radiotherapy and chemotherapy …The doctor will use a local anesthetic to numb the area of your neck. A plastic introducer sheath (a short, hollow tube through which the catheter is placed) is inserted through a small incision and into a blood vessel in the neck. A bioptome is inserted through the sheath and threaded to the right ventricle. X-rays, called fluoroscopy, are used… Read more » ...
Lizzie Rutherford Coleman, born 8 Mar 1858, died 20 Apr 1934, bur. 21 Apr 1934 - Descendents of John (Jno the Weaver) McBurney 1811-1872
0059] Although conventional wisdom until now has been to reduce the perceived frictional forces, it has been unexpectedly found that the inner housing and the outer housing of embodiments according to the present invention allow the strain that is induced by the displacement of parts of the soft inner seal elements is allowed to fully recover and maintain hemostasis because of the seal element surrounding stiff outer housing. The strain recovery provided by the interaction between the inner and outer housings reduces the extent to which the operator of the introducer sheath feels an increased amount of frictional resistance that is generated between the seals and the implement or device. In other words, it has unexpectedly been found that embodiments according to the present invention provide an acceptable frictional resistance feel when using a wide range of diameters of implements and devices while still providing complete hemostasis across the entire range of diameters. In addition, it has ...
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An 810 nm laser with a minimum of 15 W output power is used. Alternatively, a 980 nm laser can be used also with 15 W minimum output power. A 600 micron optical fibre is needed together with a guide wire introducer sheath and needle for percutaneous perforation.. Prior to treatment the SFJ and GSV are mapped through use of colour duplex ultrasound.. The guide wire introducer sheath is introduced into the GSV - at level with the knee or the lower part of the thigh. The fibre is advanced via the introducer sheath until the fibre tip is positioned 1-2 cm distal to the SFJ. A red guiding light emitted from the fibre tip provides a helpful indication of the tip position. Prior to release of the laser beam, the exact tip position is controlled carefully by use of ultrasound.. When laser is delivered by the introduced fibre, heating of the blood leads to formation of a steam bubble. That is, the effect of the laser is not achieved through contact with the wall of the blood vessel, but rather by ...
A colon lipoma is a remarkably rare tumor. In most cases, the tumors are asymptomatic and small in size, need to be differentiated from malignant tumors, and do not need any special treatment. Selection of the right surgical strategy depends on the status of bowel, as well as the size and the location of tumor. We encountered two patients with giant submucosal lipomas that had induced intussusceptions: one with a lipoma in the transverse colon and the other with a lipoma in the ascending colon. The diagnoses were made by using histological examinations ...
[Stenosing ganglioneuromatosis of the small intestine with ileus and ileal rupture].: Report on a 64-year-old man who presented with ileus and rupture of the il
NOTE: This product contains Di(2-ehylhexyl) phthalate (DEHP). Togo Medikit has conducted a Chemical Safety Assessment of DEHP in this device based on currently known acceptable exposure limits for sensitive populations (children and pregnant/nursing women), and has determined that the potential exposure is below the known acceptable exposure limits for the device when used in accordance with the indications and instructions for use.. ...
By L. Knut. The Stefan University.. As long as the needle is directed superficial until it is well aligned with the x-ray beam (see toward the final target buy generic vantin 200mg on line, needle advancement continues until Fig order cheap vantin on line. If the needle is coaxial but does not beam when the hub of the needle is superimposed on the tip lie over the final target order genuine vantin online, the needle should be removed and and appears as a radiolucent circle. Some examples a coaxial technique, small changes in needle direction can Chapter 1 Basic Techniques for Image-guided Injection 5 Figure 1-2. The Tuohy needle is among the most the most common needle used by many practitioners for image- common needles for interlaminar epidural injection using a guided injection (22-gauge with black hub, 25-gauge with light loss-of-resistance technique. The needles orifice is aligned blue hub; tip of 22-gauge needle is shown at various angles of rota- nearly perpendicular to the shaft to ...
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
Effect of Anatomical Distribution of Mast Cells on Their Defense Function against Bacterial Infections: Demonstration Using Partially Mast Cell deficient tg/tg ...
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Has anyone heard or experimented with float tanks as an intervention? Ive heard it can be beneficial, and it seems to make sense. REST or restrictive environmental stimulus therapy indicates that it could be beneficial for individuals who struggle with sensory elements by lowering the frequency of brain waves, increasing neurochemicals for joy and decreasing stress hormones. In addition, the solution of magnesium sulfate can be beneficial by cleansing and detoxifying. Just wondering if anyone has tried this ...
A catheter is disclosed which is capable of cutting obstructive tissue from a vessel of a living body while shielding a portion of the wall of the vessel from being exposed to the cutting blade at the catheters distal end. An essentially continuous outer surface at the catheters distal end allows it to be readily advanced through an introducer sheath and through a tight stenosis in an artery. The shield at the catheters distal end could subtend an arc from as little as 45 degrees to as large as 270 degrees depending on the extent of the vessel wall that is to be protected from being cut. A vacuum source at the catheters proximal end can cause a suction to exist at a cutout at the catheters distal end in order to pull obstructive tissue into the cutout as the cutting cylinder is pulled back in a retrograde direction, this suction being capable of enhancing the removal of the obstructive tissue.
A splittable medical valve is disclosed that is configured with a interfacing region that permits the valve to be placed over or inside of a tubular medical device, such as a splittable introducer sheath, to prevent loss of bodily fluids and/or reduce ingress of air-borne pathogens. The valve further includes a sealing element configured to accept passage of a medical device, such as a catheter, sheath, pacemaker lead, or other ancillary device therethrough, whereby the valve body is split along one or more lines or fissure to allow removal of the valve from around the ancillary device.
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[173 Pages Report] Interventional Cardiology Devices Market categories the Global market by type (Angioplasty, Catheters, Plaque Modification (Atherectomy, Thrombectomy), Hemodynamic Flow Alteration (Embolic Protection, Total Occlusion), Guidewire, Introducer Sheath)) & Geography
This channel includes news, techniques and new technology innovations for radial access, also called transradial access or radial artery access. This concerns the location of introducer sheaths and vascular access for interventional procedures. Radial access is supported to result in fewer complications compared to femoral access.
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RelA/p65 is a main subunit of nuclear factor-kappaB (NF-kappaB) that regulates expression of genes involved in cell growth and survival, stress response, and inflammation, but its oncogenic or tumor-suppressive function in tumorigenesis has been highly controversial. Hundreds of NF-kappaB inhibitors have been developed for targeted cancer therapy, but fail to achieve anticipated anticancer efficacy. Complexity of posttranslational modifications may contribute to tumorigenic diversity of RelA/p65, but mechanisms of action remain unclear. Here we show that phosphorylation of RelA/p65 at Ser536 functions as a tumor suppressor. In normal human colon mucosa, RelA/p65 phosphorylation at Ser536 is gradually increased with the maturation and apoptotic shedding of cryptic cells, but the phosphorylation is significantly decreased in colon tumors. In RelA/p65-silenced breast and colon cancer cells, reconstitution of a constitutively active RelA/p65, whose Ser536 was replaced by aspartic acid (named p65/S536D),
Method and apparatus for providing an introducer for transcutaneous placement of at least a portion of an analyte sensor through the skin of a patient is provided.
BioCardia®, Inc. [OTC: BCDA], a leader in the development of comprehensive solutions for cardiovascular regenerative therapies, today announced its 510(k) submission for U.S. Food and Drug Administration (FDA) clearance of the AVANCE™ steerable introducer, designed for introducing var...
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Is there any reason for the different spacing before the colons in the attached typeset formula? I have made sure that there is no space/* whatsoever between the subindex and the colon. Strange. A ...
OK, a single colon follows an access specifier, such as public: or private: or protected:, right? Are there any other situations in which a single col
Periods, colons, and semicolons all have the ability to stop a sentence in its tracks, but for very different purposes. In this lesson, learn how...
The colon is a mark of punctuation (:) used after a statement that introduces a quotation, an explanation, an example, or a series.
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The descending colon laterally (further left). Peritoneal recesses Paracolic gutters Anatomy photo:37:14-0200 at the SUNY ... This space is defined by: The ascending colon and caecum laterally (further right). The transverse colon superiorly. The root ... Paracolic gutters are recesses between the abdominal wall and the colon. These gutters are clinically important because they ... in the abdominal cavity between the colon and the root of the mesentery. There are two paramesenteric gutters; the left ...
The left colic vein drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its ... Ascending branch Descending branch Ronald W. Dudek; Thomas M. Louis (11 February 2014). High-YieldTM Gross Anatomy. Lippincott ...
The descending and sigmoid colon are typically involved. Biopsies of the affected area and the unaffected rectum confirm the ... Computed tomography of the abdomen is not routinely necessary, but may show thickening or inflammation in the distal colon ( ... Fecal calprotectin, a marker of colon inflammation, may be elevated in individuals with SCAD. Fecal calprotectin may assist in ... However, ulcerative colitis usually affects the rectum and inflammation in IBD extends to areas of the colon without ...
June 2004). "Brain activity during distention of the descending colon in humans". Neurogastroenterol. Motil. 16 (3): 299-309. ...
February 6, 1986: Rear Admiral Cristóbal Colón de Carvajal y Maroto and his driver; the Rear Admiral, descended from Cristóbal ... Asesinados en Madrid el vicealmirante Colón de Carvajal y su conductor en un atentado en el que fue herido el comandante ... Colón. June 17, 1986: 3 members of Spanish army are shot dead inside a car while driving through Madrid. July 14, 1986: Plaza ...
People with colostomies who have ostomies of the sigmoid colon or descending colon may have the option of irrigation, which ... Other locations include the ascending, transverse, and descending sections of the colon. Pouches and the stick-on appliances to ... Some common reasons are: A part of the colon has been removed, e.g. due to colon cancer requiring a total mesorectal excision, ... A part of the colon has been operated upon and needs to be 'rested' until it is healed. In this case, the colostomy is often ...
He had a number of operations, and finally his descending colon was removed. Again his health improved. McCollum was blind in ...
The lateral boundary of the retroperitoneum is defined by the ascending and descending colon. The retroperitoneum can be ...
... colon and rectum, each 2 patients; and stomach and esophagus, no patients. Lesions were limited to the second part of the ... descending) part of the duodenum, 54 patients; combined third (i.e. horizontal or inferior), and fourth (i.e. ascending) part ...
Sigmoidocele is a prolapse of peritoneum that contains a section of sigmoid colon. In females, these prolapses usually descend ... Descending perineum syndrome If the perineum descends >4 cm, descending perineum syndrome may be diagnosed. Fecal incontinence ... al.], senior editors, Bruce G. Wolff ... [et (2007). The ASCRS textbook of colon and rectal surgery. New York: Springer. pp. 47 ...
... which supply the descending and sigmoid parts of the colon; and the superior hemorrhoidal plexus, which supplies the rectum and ...
Thus, patients without adequate collateralization are at risk for ischemia of the descending and sigmoid colon. Bloody diarrhea ... If blood flow to the colon drops by more than about 50%, ischemia will develop. The arteries feeding the colon are very ... The colon receives blood from both the superior and inferior mesenteric arteries. The blood supply from these two major ... Finally, a shock phase can develop as fluids start to leak through the damaged colon lining. This can result in shock and ...
The rectum receives fecal material from the descending colon, transmitted through regular muscle contractions called ... The rectum joins with the sigmoid colon at the level of S3, and joins with the anal canal as it passes through the pelvic floor ... Colon and Rectum" (PDF), AJCC Cancer Staging Atlas, American Joint Committee on Cancer, 2006, p. 109 Wolff BG, Fleshman JW, ... The rectum is a continuation of the sigmoid colon, and connects to the anus. The rectum follows the shape of the sacrum and ...
Payr's disease is constipation due to kinking of an adhesion between the transverse and descending colon. Also a tool used in ...
This is done by adding additional :[bootstrap]:[prob] fields after the length; fields can be left empty as long as the colons ... production in those cases where having the entire tree descended from nowhere is permitted; this captures the replaced ... An unquoted string may not contain blanks, parentheses, square brackets, single_quotes, colons, semicolons, or commas. ... and colon) are prohibited. The Tree → Subtree ";" production is instead the Tree → Branch ";" ...
They drain the descending colon and sigmoid parts of the colon and the upper part of the rectum. Colorectal cancer may ...
The regions supplied by the IMA are the descending colon, the sigmoid colon, and part of the rectum. Proximally, its territory ... The SMA and IMA anastomose via the marginal artery of the colon (artery of Drummond) and via Riolan's arcade (also called the " ... All these arterial branches further divide into arcades which then supply the colon at regular intervals. The IMA is ... supplying the large intestine from the distal transverse colon to the upper part of the anal canal. ...
"Brain activity during distention of the descending colon in humans". Neurogastroenterol. Motil. 16 (3): 299-309. doi:10.1111/j. ...
... transverse and descending colons, the sigmoid colon and the rectum. Other vital organs inside the abdomen include the liver, ... The left mid-Poupart line corresponds in its upper three-quarters to the inner edge of the descending colon. The right ... It indicates roughly the transverse colon, the lower ends of the kidneys, and the upper limit of the transverse (3rd) part of ... The abdominal cavity contains most organs of the digestive system, including the stomach, the small intestine, and the colon ...
Their branches supply the lower part of the descending colon, the iliac colon, and the sigmoid or pelvic colon; anastomosing ...
In the caecum, the ascending colon, the descending colon and sigmoid colon the positions of these bands are fixed. They are- ... descending and sigmoid colon, but is situated on the anterosuperior surface of transverse colon where layers three and four of ... descending and sigmoid colon, but is placed inferiorly in the transverse colon - Second taenia, taenia mesocolica is present on ... descending and sigmoid colon, but is placed posteriorly on transverse colon at the site of attachment of transverse mesocolon ...
The hindgut contains the distal half of the transverse colon, descending colon, sigmoid colon, rectum, and superior anal canal ... The midgut contains portions of the duodenum (distal), cecum, appendix, ascending colon, and first half of the transverse colon ... colon cancer Other: pneumonia, Fitz-Hugh-Curtis syndrome Left upper quadrant Splenomegaly Colon: bowel obstruction, functional ... sigmoid colon volvulus, bowel obstruction, gas accumulation, Toxic megacolon Right low back pain Liver: hepatomegaly Kidney: ...
In front of the pancreas sits the transverse colon. The pancreas narrows towards the tail, which sits near to the spleen. It is ... Surrounded by a muscle, the sphincter of Oddi, this opens into the descending part of the duodenum. The head of the pancreas ... The peritoneum sits on top of the body of the pancreas, and the transverse colon in front of the peritoneum. Behind the ... In front sits the peritoneal membrane and the transverse colon. A small uncinate process emerges from below the head, situated ...
Lateral reflection of posterior parietal peritoneum of abdomen over the mesentery of the ascending and descending colon. The ...
Inclusion of a diagram of the colon, labeling e.g. 'sigmoid colon', 'ascending colon', 'descending colon','transverse colon' ... The squatting theory is looking better and better, now that Burkitt's hunch about fiber has failed in the case of colon cancer ...
During a dissection, the colon could be traced from the rectum, to the sigmoid colon, through the descending, transverse, and ... It is also separated from the colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon ... The cecum is an end point for the colon with a dead-end portion terminating with the appendix. The connection between the end ... It receives chyme from the ileum, and connects to the ascending colon of the large intestine. It is separated from the ileum by ...
In mammals, it includes the distal third of the transverse colon and the splenic flexure, the descending colon, sigmoid colon ... In zoology, the term hindgut refers also to the cecum and ascending colon. Arterial supply is by the inferior mesenteric artery ...
However, at the oral cavity, thoracic esophagus, ascending colon, descending colon and the rectum, the muscular layer is ...
From the arches formed by these anastomoses branches are distributed to the descending colon and the left part of the ... After a short, but variable, course, it divides into an ascending and a descending branch. The stem of the artery or its ... the descending branch anastomoses with the highest sigmoid artery. ... transverse colon. The left colic artery may be ligated during abdominal surgery to remove colorectal cancer. This may have ...
From colon 1 the ascending and transverse colon will be formed and from colon 2 the descending and sigmoid colons and the ... In tetrapods, the ileocaecal valve is always present, opening into the colon. The length of the small intestine is typically ...
Talk:Articular branches of descending genicular artery. *Talk:Articular capsule of the knee joint ... Talk:Ascending colon. *Talk:Ascending limb of loop of Henle. *Talk:Ascending lumbar vein ...
Because of this, many reptiles use the colon to aid in the reabsorption of water. Some are also able to take up water stored in ... "In states of ecstasy, lords dance a serpent dance; great descending snakes adorn and support buildings from Chichen Itza to ... Reptiles are tetrapod vertebrates, creatures that either have four limbs or, like snakes, are descended from four-limbed ...
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
... passes intact into the colon[citation needed]. Bacteria in the colon can metabolise lactose, and the resulting fermentation ... One was that most European-descended populations have a low incidence of lactose intolerance[84] and an extensive cultural ... and it reaches the colon. The bacteria in the colon, mixed with the lactose, cause acidity in stools. Stools passed after the ... The unabsorbed sugars and fermentation products also raise the osmotic pressure of the colon, causing an increased flow of ...
... who descend from Jews who settled in the Iberian Peninsula, and Mizrahi Jews, who descend from Jews who remained in the Middle ... Healthcare professionals are often taught to consider those of Ashkenazi descent to be at increased risk for colon cancer.[171] ... In the late 19th century, it was proposed that the core of today's Ashkenazi Jewry are genetically descended from a ... Was the great Eastern European Jewry of the 19th century preponderantly descended (as is normally believed) from immigrants ...
... which includes the distal 1/3 of the transverse colon, descending colon, sigmoid colon, rectum, and the anus above the ... In the large intestine,[2] the passage of the digesting food in the colon is a lot slower, taking from 30 to 40 hours until it ... ascending colon, and the proximal 2/3 of the transverse colon. ... The largest part of the GI tract is the colon or large ... Some vitamins, such as biotin and vitamin K produced by bacteria in the gut flora of the colon are also absorbed. ...
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
குறுக்குக் குடலின் இறுதி மூன்றில் ஒரு பகுதி, இறங்கு பெருங்குடல் (descending colon), மலக்குடல் (rectum), மலத்துவாரத்தின் ... Ascending colon), குறுக்குப் பெருங்குடலின் மூன்றில் இரு பகுதி ...
... descended from Heaven and awakened Ishmael with a "wind-spout" that whirled toward him. The Angel then commanded the ... Significant among the private breeders in continental Europe was Spain's Cristóbal Colón de Aguilera, XV Duque de Veragua, a ... discussing whether some horses descend from "impure" animals that cannot be traced to the desert Bedouin.[190] The major ... are those horses in North America that can reasonably be assumed to descend entirely from bedouin Arabian horses bred by horse- ...
While they are ancestrally and genealogically descended from groups that migrated from Lesser Antilles, many Garifuna today are ... Mirtha Colón. *Abraham Laboriel. *Abe Laboriel Jr.. *Aurelio Martinez. *Bernard Martínez Valerio ...
In the human female, the urethra is about 1.9 inches (4.8 cm) to 2 inches (5.1 cm) long and exits the body between the clitoris and the vagina, extending from the internal to the external urethral orifice. The meatus is located below the clitoris. It is placed behind the symphysis pubis, embedded in the anterior wall of the vagina, and its direction is obliquely downward and forward; it is slightly curved with the concavity directed forward. The proximal 2/3rds is lined by transitional epithelium cells while distal 1/3rd is lined by stratified squamous epithelium cells.[10] The urethra consists of three coats: muscular, erectile, and mucous, the muscular layer being a continuation of that of the bladder. Between the superior and inferior fascia of the urogenital diaphragm, the female urethra is surrounded by the urethral sphincter. Somatic (conscious) innervation of the external urethral sphincter is supplied by the pudendal nerve. ...
Colon. *Ascending colon. *Hepatic flexure. *Transverse colon. *Splenic flexure. *Descending colon. *Sigmoid colon ...
Hindgut တွင် အူမကြီး၏ Transverse colon နောက်ပိုင်း ၃ ပုံ ၁ ပုံ၊ descending colon, sigmoid colon, rectum, anus (စအို) တို့ ပါဝင် ... ascending colon, transverse colon ၏ ရှေ့ ၃ ပုံ ၂ ပုံ ပါဝင်သည်။ ...
... s are now thought to have descended from a South American ancestor,[21] while the Indian Ocean tortoises ... todas las tierras que forman las islas del Archipiélago de Colón o Galápagos, Registro Oficial No. 873 (1959) Quito, 20 de ... Günther hypothesized that all the giant tortoises descended from a single ancestral population which spread by sunken land ... while the four southern populations are believed to be descended from a second colonization from the more southerly island of ...
Colon. ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon. continuous (taenia ...
The match centered around Maryse keeping her distance from James before descending to the floor in an attempt to use a can of ... The Colóns, and Rhodes and DiBiase (collectively known as The Legacy).[19] Two weeks following the event on the July 6 episode ...
... and that thus even the inhabitants of that distant region are descended from that one first man.[82] ...
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
Descending perineum syndrome. *Other inability or unwillingness to control the external anal sphincter, which normally is under ... Deeper psychosomatic disorders which sometimes affect digestion and the absorption of water in the colon ... Firestone Baum, C; John A; Srinivasan K; Harrison P; Kolomensky A; Monagas J; Cocjin J; Hyman PE (January 2013). "Colon ...
Maragul bituka: Cecum • Colon (ascending colon, transverse colon, descending colon, sigmoid colon) • Rectum (Houston valve, ...
Colon, Jorge. "A Call for a Response From The International Chemistry Community. (Science For Haiti)." Chemistry International ... Logan attributed this disparity to racism, even though citizens of both countries were descended from African slaves.[17] The ... Machlis, Gary E, Jorge Colón, and Jean E. McKendry. Science for Haiti: A Report on Advancing Haitian Science and Science ...
In front of the pancreas sits the transverse colon.[4]. The pancreas narrows towards the tail, which sits next to the spleen.[4 ... Surrounded by a muscle, the sphincter of Oddi, this opens into the descending part of the duodenum.[4] ... Behind rests the inferior vena cava, and in front sits the peritoneal membrane and the transverse colon.[4] ... To the right sits the descending part of the duodenum, and between these travel the superior and inferior pancreaticoduodenal ...
Colon. ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon. continuous (taenia ...
Iliac colon, sigmoid or pelvic colon, and rectum seen from the front, after removal of pubic bones and bladder. ... In the female the anterior fibers of the levator ani descend upon the side of the vagina. ... the anterior fibers descend upon the side of the prostate to unite beneath it with the muscle of the opposite side, joining ...
পরিপাকতন্ত্রের শারীরবৃত্তে কোলন বা বৃহদন্ত্র (বৃহৎ +অন্ত্র) (ইংরেজি: Colon) পরিপাকনালীর সেই অংশ যা মল থেকে পানি নিষ্কাশন করে। ... ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ... Colon Function And Health Information ওয়েব্যাক মেশিনে আর্কাইভকৃত ৫ সেপ্টেম্বর ২০১২ তারিখে Retrieved on 2010-01-21 ...
The nerve then traverses the retroperitoneum, descending over the anterior surface of the psoas.[11] ... Care should be taken around the abdominal organs, especially the colon when palpating deeply. ...
A failure in this process can cause indirect inguinal hernia or an infantile hydrocoele.[citation needed]The testes descend ...
Each colon moves the comment farther to the right, so if the person above you used 3 colons (:::) you should use 4 (::::). To ... Roughly in descending order of quality, lower-quality evidence in medical research comes from individual RCTs; other controlled ... To make conversations easier to follow, place your comments below the one you are responding to and indent it using a colon ...
Finally, the outermost anterior layer of the descending colon is visceral peritoneum; on the posterior of the descending colon ... The descending colon is a segment of the large intestine and is the third and penultimate segment of the colon. It transports ... During defecation, the descending colon helps to propel feces toward the sigmoid colon and rectum and eventually out of the ... At its superior end, the descending colon connects to the transverse colon at the splenic flexure just inferior to the spleen. ...
The colon is part of the large intestine, the final part of the digestive system. Its function is to reabsorb fluids and ... The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon. ... Descending colon. Descending colon. Medically reviewed by the Healthline Medical Network - Written by the Healthline Editorial ... The descending colon stores the food to be emptied into the rectum. The colon is held in place by peritoneum, a thin layer of ...
The colon is part of the large intestine, the final part of the digestive system. Its function is to reabsorb fluids and ... The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon. ... The descending colon stores the food to be emptied into the rectum. The colon is held in place by peritoneum, a thin layer of ... The descending colon is located on the left side of the large intestine, extending from the bend below the spleen to the ...
The descending colon is part of the large intestine that passes along the side of the left kidney. Problems with the descending ... They include the ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, and sigmoid colon. This ... The large intestine includes the vermiform appendix, the cecum and the colon. The descending colon is part of the colon, which ... Colon pain is one of the common descending colon cancer symptoms, but by itself it isnt enough to make a diagnosis. Colon pain ...
... many casual mentions of the left colon chiefly concern the descending colon. The descending colon begins at the splenic flexure ... Cancer of the descending colon is a serious disease. A person can have colon cancer yet have no symptoms in the early stages. ... The descending colon is on the left side of the body (barring any malformations). The term left colon is hypernymous to ... the descending colon is the part of the large intestine from the splenic flexure to the beginning of the sigmoid colon. The ...
Find the most comprehensive real-world treatment information on Descending Colon Resection at PatientsLikeMe. 0 patients with ... bipolar I disorder or psoriasis currently have Descending Colon Resection. ... What is Descending Colon Resection?. Category: Surgeries false A descending colon resection (colectomy) is a type of surgery ... Stopped having Descending Colon Resection Duration. Patients. This item is relevant to you: Less than 1 month 1 * 1 ...
The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending ... The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending ... http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Descending_Colon SYN LOOM ... colon lying in the left iliac fossa is sometimes called the iliac colon. ...
ICD-10-PCS code 0DTM0ZZ for Resection of Descending Colon, Open Approach is a medical classification as listed by CMS under ... Resection of Descending Colon, Open Approach 0DTM0ZZ. ICD-10-PCS code 0DTM0ZZ for Resection of Descending Colon, Open Approach ... Descending Colon. Definition: Cutting through the skin or mucous membrane and any other body layers necessary to expose the ...
ICD-10-PCS code 0D7M4ZZ for Dilation of Descending Colon, Percutaneous Endoscopic Approach is a medical classification as ...
A rare case of Wild-Type GIST of descending colon with GANT characteristics.(Letter to the editor) by The Turkish Journal of ... colon+with+GANT...-a0589800473. *APA style: A rare case of Wild-Type GIST of descending colon with GANT characteristics.. (n.d ... On endoscopic examination of the colon, a pedunculated mass partially obliterating the lumen of the descending colon was ... MLA style: "A rare case of Wild-Type GIST of descending colon with GANT characteristics.." The Free Library. 2019 AVES 14 Aug. ...
A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral ... "AJCC: colon and rectum," in AJCC Cancer Staging Manual, S. B. Edge, D. R. Byrd, C. C. Compton, A. G. Fritz, F. L. Greene, and A ... Report of a case," Diseases of the Colon and Rectum, vol. 26, no. 6, pp. 390-392, 1983. View at Google Scholar · View at Scopus ... J.-Y. Yang, J.-K. Lee, S.-M. Cha, and Y.-B. Joo, "Psoas abscess caused by spontaneous rupture of colon cancer," Clinics in ...
A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral ... Alban Cacurri, Gaspare Cannata, Stefano Trastulli, et al., "A Rare Case of Perforated Descending Colon Cancer Complicated with ...
Human Colon descending (Normal) tissue lysate, GTX28698, Applications: ELISA, IP, WB; ELISA, Immunoprecipitation, Western Blot ... Human Colon descending (Normal) lysate, Human Colon descending (Normal) tissue extract. Lysate Fraction. Whole Cell Extract/ ... Human Colon descending (Normal) tissue lysate See all Human Colon lysate products ...
Short description: DESCENDING COLON INJ-OPN.. *ICD-9-CM 863.53 is a billable medical code that can be used to indicate a ... Injury to descending (left) colon with open wound into cavity. * ... colon 863.40. *. with*. open wound into cavity 863.50. *. ... 2015/16 ICD-10-CM S36.502A Unspecified injury of descending [left] colon, initial encounter ...
Congenital Descending Colonic Stenosis with Perforation of Transverse Colon in a Neonate: A Case Report * R Hamid Senior ... PHOTOGRAPH SHOWING STENOTIC SEGMENT OF DESCENDING COLON * POST OPERATIVE PHOTOGRAPH OF SAME PATIENT WITH END COLOSTOMY WITH ... At the junction of descending and sigmoid colon a stenosis was found, laparotomy also revealed a perforation of transverse ... INTRAOPERATIVE PHOTOGRAPH SHOWING STENOSIS SEGMENT OF DESCENDING COLON * INTRAOPERATIVE PHOTOGRAPH SHOWING STENOTIC SEGMENT OF ...
The descending colon is supplied by the artery, a branch of the _ artery. A. left colic inferior mesenteric B. left colic ... The descending colon is supplied by the _____ artery, a branch of the _____ artery. A.left colic inferior mesenteric B.left ... The descending colon is supplied by the artery, a branch of the _ artery. left colic inferior mesenteric B. left colic superior ...
The retrograde tracer fast blue (FB) was injected into the descending colons of all animals and then tissue comprising IMGs ... neurons projecting to the colon exhibit calbindin-like immunoreactivity. It is not known if there are any changes in the ... Neurons in the ENS of the Porcine Descending Colon. *Krystyna Makowska, Kazimierz Obremski, Lukasz Zielonka, Slawomir Gonkowski ... distribution in intramural nervous structures of the porcine descending colon. *Slawomir Gonkowski, Krystyna Makowska, Jaroslaw ...
Malignant neoplasm of descending colon. 2016 2017 2018 Billable/Specific Code *C18.6 is a billable/specific ICD-10-CM code that ... Primary malignant neoplasm of descending colon. ICD-10-CM C18.6 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0): * ... Malignant neoplasm of colon. 2016 2017 2018 Non-Billable/Non-Specific Code Type 1 Excludes*malignant carcinoid tumors of the ... Cancer of the colon, descending. *Primary adenocarcinoma of descending colon. * ...
Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon. / Browning, ... Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon. ... N2 - Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and ... AB - Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and ...
... by Etienne Moore - last modified 2007-04-02 18:09 ... This is part of the left colon lying in the left side of the abdomen. ...
... transverse colon, splenic flexure, descending colon, and sigmoid colon. The descending colon passes down through the upper back ... The descending colon is a part of the colon, which is made up of several parts. They include the ascending colon, hepatic ... Descending Colon The descending colon of humans passes downward through the left hypochondrium and lumbar regions, along the ... Cancer of the descending colon is the most serious of the diseases. A person can have colon cancer yet have no symptoms in the ...
... May 25, 2017 Anatomy The small intestine connects to the colon where a valve regulates ... the descending colon. The colon is responsible for resabsorption of water and collect undigested waste for elimination. The ... As the colon moves towards the head, it is called the ascending colon. It then moves laterally across the abdomen where it is ... The cecum is a pouch-like section of the large intestine that is the first part of the colon, also called the large intestine. ...
... GeneralEquipmentPreparationImplementationFollow-up. General. For cancer in the descending colon ... Oncolex - cancer encyclopedia › About cancer in the colon/rectum › Treatment › Surgery colon › Tumor in descending ... Surgery colonTumor in cecum and ascending Tumor in right flexure Tumor in transversumTumor in left flexure Tumor in descending ... The bowel is divided to the left on the transverse colon and upwards on the rectum. The distal sigmoid colon is not being ...
Primary blast injury of descending [left] colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code *S36.512 should ... Unspecified injury of descending [left] colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code ... Primary blast injury of colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code Applicable To*Blast injury of colon ... Injury of colon. 2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code Type 2 Excludes*injury of rectum (S36.6-) ...
Descending colon, Transversus abdominis muscle, Internal abdominal oblique muscle, External abdominal oblique muscle, Quadratus ...
Diagram descending colon - Abdomen - Wikipedia, the free encyclopedia. Bowtrol is formulated to maximize ones elimination ... The colon and rectum are parts of the digestive... ascending colon, transverse colon, descending colon, and sigmoid colon... ... CARCINOMA OF THE COLON. STAGING DIAGRAM. SITE: Ascending Colon. Cecum Colon, NOS Descending Colon Hepatic Flexure of Colon. ... The last part of the colon. The distal colon includes the descending colon (the left side of the colon) and the sigmoid colon ( ...
... descending colons explanation free. What is descending colons? Meaning of descending colons medical term. What does descending ... Looking for online definition of descending colons in the Medical Dictionary? ... descending colon. (redirected from descending colons). Also found in: Dictionary, Thesaurus, Encyclopedia. de·scend·ing co·lon ... Synonym(s): colon descendens [TA]. de·scend·ing co·lon. (dĕ-sending kōlŏn) [TA] The part of the colon extending from the left ...
The ICD-10 Code D12.4 is the code used for Benign neoplasm of descending colon .An alternative description for this code is ...
It is located at the end of the left colon ... The sigmoid is the area of the descending colon (before the ... descending colon - sigmoid. Published on Digestive system.. The sigmoid is the area of the descending colon (before the rectum ... It is located at the end of the left colon or descending colon, followed by the rectum and the anus. ... Cancer of the descending colon is more frequent in the sigmoid and the rectum. ...
  • It transports feces from the transverse colon inferiorly along the left side of the abdominal cavity to the sigmoid colon. (innerbody.com)
  • From the splenic flexure, the descending colon extends inferiorly toward the left hip before turning about 90 degrees to the right and forming the sigmoid colon. (innerbody.com)
  • During defecation, these muscle cells contract in waves of peristalsis to push feces down the colon toward the sigmoid colon. (innerbody.com)
  • During defecation, the descending colon helps to propel feces toward the sigmoid colon and rectum and eventually out of the body by contraction of its smooth muscle tissue. (innerbody.com)
  • The descending colon is located on the left side of the large intestine, extending from the bend below the spleen to the sigmoid colon. (healthline.com)
  • In the anatomy of humans and homologous primates, the descending colon is the part of the large intestine from the splenic flexure to the beginning of the sigmoid colon. (wikipedia.org)
  • It passes downward through the left hypochondrium and lumbar regions, along the outer border of the left kidney and ends at the lower left part of the abdomen where it continues as the sigmoid colon. (wikipedia.org)
  • Retroperitoneal abscess complicated with necrotizing fasciitis of the thigh in a patient with sigmoid colon cancer," World Journal of Surgical Oncology , vol. 7, article 74, 2009. (hindawi.com)
  • C. M. Peterson, J. G. Allison, and C. C. Lu, "Psoas abscess resulting from perforating carcinoma of the sigmoid colon. (hindawi.com)
  • At the junction of descending and sigmoid colon a stenosis was found, laparotomy also revealed a perforation of transverse colon. (nepjol.info)
  • Transverse colostomy and a mucous fistula of sigmoid colon was performed after resecting stenosing segment and colon distal to perforation site upto stenosing site. (nepjol.info)
  • The distal sigmoid colon is not being retained because the blood supply may not remain satisfactory. (oncolex.org)
  • The sigmoid is the area of the descending colon (before the rectum) where faeces accumulate prior to being released. (flowsandforms.com)
  • Cancer of the descending colon is more frequent in the sigmoid and the rectum. (flowsandforms.com)
  • The colon is divided into four main sections--ascending or right colon, transverse colon, descending or left colon, and the sigmoid colon. (livestrong.com)
  • The sigmoid colon is considered a part of the left colon. (livestrong.com)
  • The colonic contents travel from the small intestine up the ascending colon then along the transverse colon then down the descending colon and sigmoid before entering the rectum. (livestrong.com)
  • Though these symptoms may also be seen in cancers in the right colon, they are most often seen in the left because the stool is more solid in the descending and sigmoid colon. (livestrong.com)
  • In our body's large intestine , the Descending Colon is the segment of the colon , between the Transverse Colon and the sigmoid colon . (wellnessadvocate.com)
  • In our body's colon , the Descending Colon passes downward through the left hypochondrium and lumbar regions, along the lateral border of the left kidney , at the lower end of the kidney it turns medialward toward the lateral border of the psoas muscle, and then descends, in the angle between psoas and quadratus lumborum, to the crest of the ilium, where it ends in the sigmoid colon . (wellnessadvocate.com)
  • The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. (colonoscopyandendoscopybilling.com)
  • The sigmoid colon is the part of the large intestine after the descending colon and before the rectum. (colonoscopyandendoscopybilling.com)
  • The walls of the sigmoid colon are muscular, and contract to increase the pressure inside the colon, causing the stool to move into the rectum. (colonoscopyandendoscopybilling.com)
  • The sigmoid colon is supplied with blood from several branches (usually between 2 and 6) of the sigmoid arteries, a branch of the IMA. (colonoscopyandendoscopybilling.com)
  • Its four parts are the ascending colon , transverse colon , descending colon and sigmoid colon . (cancerqld.org.au)
  • The rectum extends through the pelvis from the end of the sigmoid colon to the anus. (limamemorial.org)
  • Colored x-ray of the large intestine of a patient with sigmoid colon cancer after a barium (white) enema. (clinicaladvisor.com)
  • What causes erythematous mucosa in the sigmoid colon? (healthtap.com)
  • Can mild thickening and fat in wall of large bowel including sigmoid colon and right colon on CT scan be normal? (healthtap.com)
  • CECT whole abdomen with rectal contrast shows mild thickening of mucosal folds in sigmoid colon. (healthtap.com)
  • Control colon showing no more than mild autolysis was taken at autopsy from 6 patients (aged 2 months to 4 years) in whom there was no evidence of colonic disease, and for each case sections from rectum, sigmoid, and ascending and transverse colon were selected. (thefreelibrary.com)
  • The person living with a descending or sigmoid colostomy has the option of managing their colostomy with irrigation. (cancer.org)
  • I was sent for a colonoscopy, and a mass was discovered which was determined to be stage 3B cancer of the sigmoid colon. (medicinenet.com)
  • The rectum measures six to 12 inches long and is located between the sigmoid colon and the anus . (verywellhealth.com)
  • The descending colon stores the food to be emptied into the rectum. (healthline.com)
  • The function of the descending colon in the digestive system is to store the remains of digested food that will be emptied into the rectum. (wikipedia.org)
  • The bowel is divided to the left on the transverse colon and upwards on the rectum. (oncolex.org)
  • It is located at the end of the left colon or descending colon, followed by the rectum and the anus. (flowsandforms.com)
  • Impaction of the descending colon was palpated per rectum where gas distention of the ascending colon prevented any further evaluation. (clinicabagnarola.it)
  • Colorectal cancer (also known as colon cancer, rectal cancer, or bowel cancer) is the development of cancer in the colon or rectum (parts of the large intestine). (icd.codes)
  • Lymphatic drainage from the entire colon and proximal two-thirds of the rectum is to the paraaortic lymph nodes that then drain into the cisterna chyli. (colonoscopyandendoscopybilling.com)
  • An operation for rectal cancer, which involves removing part of the colon and the rectum and anus and creating a permanent colostomy. (cancerqld.org.au)
  • The large bowel includes the colon and the rectum. (cancerqld.org.au)
  • Its four main sections are the caecum, colon , rectum and anus. (cancerqld.org.au)
  • Removal of the entire colon and the rectum is called a proctocolectomy. (medlineplus.gov)
  • Removal of all of the colon but not the rectum is called subtotal colectomy. (medlineplus.gov)
  • Thought you might appreciate this item(s) I saw at Diseases of the Colon & Rectum. (lww.com)
  • This is the small "S" shaped part of the colon, about 40 cm in length, which goes from the bottom of the descending colon into the centre of the pelvis to the rectum . (wikipedia.org)
  • Forces the stool produced in colon to the rectum. (prezi.com)
  • descending colon and rectum. (celiac.com)
  • The variant blood supply to the descending colon, rectosigmoid and rectum based on 400 dissections. (lww.com)
  • Tumors or cancer of the COLON or the RECTUM or both. (bioportfolio.com)
  • Cancer cells within the colon or rectum are called adenocarcinoma. (loyolamedicine.org)
  • colon cancer begins specifically in the colon while rectal cancer begins in the rectum. (loyolamedicine.org)
  • Colonoscopy , or an examination of the entire rectum and colon using a scoping tool, is the most common method used to identify the presence of cancer cells or tumors in the colon. (loyolamedicine.org)
  • In the caudal abdomen the colon curves to the midline and joins the rectum. (thefreedictionary.com)
  • In the horse there is the additional oddity of a significant reduction in diameter at the small colon, the terminal part which joins the rectum. (thefreedictionary.com)
  • the third and last of the three main divisions of the colon which runs caudally and terminates in the rectum. (thefreedictionary.com)
  • The rectum is a part of the colon, and both organs together are called the large intestine. (verywellhealth.com)
  • Flare since '12 descending colon to rectum. (healingwell.com)
  • The large intestine includes the vermiform appendix , the cecum and the colon. (wisegeek.com)
  • The cecum is a pouch-like section of the large intestine that is the first part of the colon, also called the large intestine. (anatomycorner.com)
  • It is the part of the colon from the cecum to the hepatic flexure (the turn of the colon by the liver). (colonoscopyandendoscopybilling.com)
  • In ruminant grazing animals, the cecum empties into the spiral colon. (colonoscopyandendoscopybilling.com)
  • This part of the colon goes from the cecum (where the small intestine ends) up the right hand side of the abdomen . (wikipedia.org)
  • wall, large colon, and cecum. (cdc.gov)
  • the segment of the colon that extends up the cecum in the lower right side of the colic fissure to the abdomen to the transverse colon at the hepatic flexure on the right side. (thefreedictionary.com)
  • There is an ascending colon which begins at the cecum, passes forward to the cranial part of the abdominal cavity then crosses to the left side as the transverse colon. (thefreedictionary.com)
  • In the horse the ascending colon forms an uncoiled loop reflexed upon itself, beginning at the cecum as the right ventral colon, passing to the left ventral, to the left dorsal at the pelvic flexure, then to the right dorsal, then back into the standard pattern at the transverse colon. (thefreedictionary.com)
  • At its superior end, the descending colon connects to the transverse colon at the splenic flexure just inferior to the spleen. (innerbody.com)
  • The descending colon begins at the splenic flexure at the upper left part of the abdomen. (wikipedia.org)
  • Computed tomography (CT) scan demonstrated a prestenotic distension of the splenic flexure of the colon with thickening of the bowel wall and an intraluminal multi-lobular formation (Figure 1). (thefreelibrary.com)
  • What is Descending Colon Resection? (patientslikeme.com)
  • A descending colon resection (colectomy) is a type of surgery done to remove all or part of your large bowel (large intestine or colon). (patientslikeme.com)
  • There are no evaluations for Descending Colon Resection. (patientslikeme.com)
  • ICD-10-PCS code 0DTM0ZZ for Resection of Descending Colon, Open Approach is a medical classification as listed by CMS under Gastrointestinal System range. (aapc.com)
  • For cancer in the descending colon, a left-sided hemicolectomy and a standard bowel- and lymph node resection are performed. (oncolex.org)
  • Resection and anastomosis of the descending colon in 43 horses. (elsevier.com)
  • 6 months) term survival, (2) factors associated with short-term survival, and (3) the perioperative course for horses with resection and anastomosis of the descending colon. (elsevier.com)
  • Horses (n=43) that had descending colon resection and anastomosis. (elsevier.com)
  • Medical records (January 1995-June 2009) of 7 equine referral hospitals were reviewed for horses that had descending colon resection and anastomosis and were recovered from anesthesia. (elsevier.com)
  • Complications include postoperative fever and diarrhea but the prognosis is good after small colon resection and anastomosis. (elsevier.com)
  • Colon resection of descending colon. (healthtap.com)
  • Over 2 years post low anterir colon resection. (healthtap.com)
  • Had lower colon resection and still have pain when "going" after 8 months. (healthtap.com)
  • Why is colon resection still done for colon cancer in cases with liver metastasis? (healthtap.com)
  • Colon resection from cancer. (healthtap.com)
  • I'm having a laparoscopic colon resection surgery on the 25th. (healthtap.com)
  • I had a colon resection done by da Vinci on Thursday. (healthtap.com)
  • I had a colon resection surgery one year ago diagnosed stage 1 colon cancer. (healthtap.com)
  • 3 years after my colon resection. (healthtap.com)
  • Can I eat fiber after colon resection? (healthtap.com)
  • The recommended standard of care for patients after resection of stage III colon cancer is adjuvant 5FU-based chemotherapy - FOLFOX (fluorouracil, leucovorin with oxaliplatin) - or CAPOX (capecitabine. (bioportfolio.com)
  • Baseline computed tomography (CT) of the chest, abdomen, and pelvis with contrast and carcinoembryonic antigen (CEA) are the preferred cost-effective, colon-cancer staging studies done before surgical resection. (nih.gov)
  • Surgical resection is the main treatment modality for localized early-stage colon cancer. (nih.gov)
  • They had to remove a foot and a half of my small colon (doing a resection), my appendix , one ovary, and part of the large colon. (medicinenet.com)
  • Patients with metachronous peritoneal metastasis after curative resection for stage I-III colon cancer were retrospectively reviewed, and the incidence and prognosis of metachronous peritoneal metastasis were investigated. (nih.gov)
  • A proportion of colon cancer patients with metachronous peritoneal metastasis may benefit from combined peritoneal nodule resection and systemic chemotherapy. (nih.gov)
  • While the first part of the large intestine is responsible for the absorption of water and other substances from the chyme, the main function of the descending colon is to store waste until it can be removed from the body in solid form, when a person has a bowel movement. (wikipedia.org)
  • Among the most common are the inflammatory bowel diseases (such as ulcerative colitis or Crohn's disease) and colon cancer. (wikipedia.org)
  • Inflammatory bowel diseases (IBD), including Crohn's disease (CD), and ulcerative colitis (UC), are a group of inflammatory conditions related to the colon and small intestines and characterized by chronic inflammation. (frontiersin.org)
  • The large bowel is also called the large intestine or colon. (medlineplus.gov)
  • Removing the right colon and valve that separates the small bowel from colon sets the stage for bacterial contamination of the small bowel, which leads to diarrhea commonly-can be treated, with good success. (healthtap.com)
  • Signs and symptoms of colon cancer are very similar to symptoms of inflammatory bowel disease and other gastrointestinal illnesses. (loyolamedicine.org)
  • Bowel inflammation, which often occurs in inflammatory bowel disease , also increases the risk of developing colon cancer. (loyolamedicine.org)
  • Irrigation is simply putting water into the colon through the stoma to help regulate bowel movements. (cancer.org)
  • There are several factors that increase a person's chance of developing colon cancer, some within a person's control (for example, being overweight and leading a sedentary lifestyle) and some not (for example, having an inflammatory bowel disease). (verywellhealth.com)
  • Safety and efficacy of endoscopic colonic stenting as a bridge to surgery in the management of intestinal obstruction due to left colon and rectal cancer: a systematic review and meta-analysis," Surgical Oncology , vol. 22, no. 1, pp. 14-21. (hindawi.com)
  • it is concluded that, in addition to their previously described depressant actions on neuro-effector transmission to colonic smooth muscle, pancreatic polypeptides can exert powerful inhibitory effects on myenteric neurones of the descending colon. (elsevier.com)
  • Absorption of water and Na + in descending colonic crypts is dependent on the barrier function of the surrounding myofibroblastic pericryptal sheath. (beds.ac.uk)
  • Here the effects of high and low Na + diets and exposure to whole body ionising radiation on the growth and activation of the descending colonic pericryptal myofibroblasts are evaluated. (beds.ac.uk)
  • These results demonstrate an activation of descending colonic myofibroblasts to trophic stimuli, or irradiation, which can be attenuated by Captopril, indicative of local trophic control by angiotensin II and TGF-β release. (beds.ac.uk)
  • It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon. (bioportfolio.com)
  • This part of the colon passes down through the upper back portion of the abdomen and along the side of the left kidney . (wisegeek.com)
  • This is part of the left colon lying in the left side of the abdomen. (sussexsurgery.com)
  • It then moves laterally across the abdomen where it is called the transverse colon and finally makes the turn to head toward the posterior of the body, the descending colon . (anatomycorner.com)
  • The ascending colon, on the right side of the abdomen, is about 25 cm long in humans. (colonoscopyandendoscopybilling.com)
  • The portion of colon that begins in the lower right part of the abdomen, departing from the end of the small intestine. (oreilly.com)
  • Colored x-ray of the abdomen (frontal) after a double contrast barium enema highlighting cancer of the left descending colon. (clinicaladvisor.com)
  • The first segment of the colon, which begins in the right lower quadrant of the abdomen at the caecum and ends at the hepatic (right colic) flexure in the right upper quadrant of abdomen, after which point it becomes the transverse colon. (thefreedictionary.com)
  • In the ruminants and the pig this takes the form of a spiral colon of centrifugal and centripetal loops which occupies the right side of the abdomen. (thefreedictionary.com)
  • The colon is located around the perimeter of the abdomen and is about five feet in length. (verywellhealth.com)
  • In 2012, there will be 103,170 new cases of colon cancer and 40,290 new cases of rectal cancer diagnosed. (clinicaladvisor.com)
  • The term "colon cancer" is often blended with the term "rectal cancer" to form the hybrid term colorectal cancer. (loyolamedicine.org)
  • The term colon cancer is sometimes used interchangeably with colorectal cancer because colon and rectal cancer share common features. (verywellhealth.com)
  • C18.6 is a billable ICD code used to specify a diagnosis of malignant neoplasm of descending colon. (icd.codes)
  • The ascending colon is wider than its descending counterpart, which allows for more growth of tumor before the tumor causes symptoms. (livestrong.com)
  • Colored x-ray of the colon highlighting a large tumor (green area), which is causing the narrowing of the large intestine with possible obstruction. (clinicaladvisor.com)
  • This malignant tumor type begins as a benign polyp (abnormal tissue growth from the mucous lining of the colon), hence its reason for removal. (clinicaladvisor.com)
  • Sr. Dowling had a tumor in his descending colon and some heart issues. (oneradionetwork.com)
  • The Function Of The Colon Retrieved on 2010-01-21 Lotti M. Anatomy in relation to left colectomy Anatomy figure: 37:06-06 at Human Anatomy Online, SUNY Downstate Medical Center - "The large intestine. (wikipedia.org)
  • The Colon (Human Anatomy): Picture, Function, Definition. (drug-purchase.info)
  • These symptoms are explained by the anatomy of ascending colon. (livestrong.com)
  • The symptoms of left-sided colon cancer are attributed the anatomy of that area of the colon. (livestrong.com)
  • What Are the Treatments for Malignant Colon Polyps? (livestrong.com)
  • What are the most common polyps found in the colon? (brainscape.com)
  • Pendunculated polyps hang off ___ attached to the walls of the colon. (brainscape.com)
  • I never would've thought polyps or colon cancer, no family members had it. (medicinenet.com)
  • Most colon cancers are caused by growths within the inner lining of the colon, called polyps, that change into cancer over many years. (verywellhealth.com)
  • Feces passing through the descending colon are stored until they are ready to be eliminated from the body. (innerbody.com)
  • The walls of the descending colon absorb water as well as remaining nutrients and vitamins from the feces, depositing these valuable substances into our bloodstream. (innerbody.com)
  • It contains many small pouches, known as haustra, along its length that increase its surface area and help to move feces through the colon. (innerbody.com)
  • The mucus secreted from goblet cells in the mucosa layer provides lubrication to feces moving through the lumen, protecting the delicate tissues of the colon. (innerbody.com)
  • By the time feces reach the descending colon, the vast majority of nutrients, vitamins and water have been extracted by the ascending and transverse colon, leaving mostly waste products. (innerbody.com)
  • Still, some absorption of water and vitamins produced by bacterial fermentation of feces - including vitamins K, B1, B2 and B12 - does occur in the descending colon. (innerbody.com)
  • Symptoms on the left side of the colon are usually caused by growth outward into the lumen, obstructing the flow of feces. (livestrong.com)
  • The colon takes water from the feces that goes through it. (wikipedia.org)
  • It goes underneath the stomach and the pancreas and joins the descending colon near the spleen . (wikipedia.org)
  • Characteristic findings include a palpable medial displacement of the spleen and the absence of the pelvic flexure of the colon from its usual site in front of the pelvis. (thefreedictionary.com)
  • My colonoscopy: the descending colon mucosa is "erythematous, hemorrhagic, ulcerated, and to show loss of vascular markings suggestive of stercoral ulcers due to constipation. (celiac.com)
  • In the meantime, for your piece of mind, a home FIT (fecal immunochemical test) can be performed & will pick up 79% of colon cancers with a single screen (the rate is closer to 95% for colonoscopy). (healthtap.com)
  • In almost all patients, a diagnostic or screening colonoscopy is required for tissue biopsy pathological confirmation of colon carcinoma. (nih.gov)
  • My colon cancer diagnosis was established by colonoscopy biopsy followed by lower gastro intestinal CT with contrast, and confirmed by urgent surgery. (medicinenet.com)
  • On endoscopic examination of the colon, a pedunculated mass partially obliterating the lumen of the descending colon was detected (Figure 2). (thefreelibrary.com)
  • CopperPipe -- Colon pain is one of the common descending colon cancer symptoms, but by itself it isn't enough to make a diagnosis. (wisegeek.com)
  • A displacement of the ascending colon was the most likely diagnosis, based on distention detected by rectal palpation. (clinicabagnarola.it)
  • How was the diagnosis of your colon cancer established? (medicinenet.com)
  • For example, mucinous adenocarcinoma is one subtype that produces excessive mucous and tends to be found on the right side of the colon. (verywellhealth.com)
  • The ascending colon (or right colon) is the beginning part of the colon. (healthline.com)
  • The appendicular vein removes oxygen-depleted blood from the appendix, which is located at the bottom of the ascending colon. (healthline.com)
  • Abdominal wall and thigh abscess resulting from the penetration of ascending colon cancer," Acta Medica Okayama , vol. 59, no. 6, pp. 281-283, 2005. (hindawi.com)
  • As the colon moves towards the head, it is called the ascending colon . (anatomycorner.com)
  • Also the tumors that develop in the ascending colon tend to grow along the wall of the colon instead of directly outward into the lumen. (livestrong.com)
  • The stool is still in liquid form in the ascending colon. (livestrong.com)
  • Abdominal exploration showed a normal small intestine and the ascending colon was in regular position, despite distention. (clinicabagnarola.it)
  • The ascending colon is supplied by parasympathetic fibers of the vagus nerve (CN X). (colonoscopyandendoscopybilling.com)
  • Arterial supply of the ascending colon comes from the ileocolic artery and right colic artery, both branches of the SMA. (colonoscopyandendoscopybilling.com)
  • This part of the colon goes across the from the ascending colon. (wikipedia.org)
  • The right colon (the ascending colon plus half the transverse colon) mainly enables absorption of water. (ikonet.com)
  • In herbivores and omnivores there is a variation on this general plan in that the ascending colon is greatly lengthened. (thefreedictionary.com)
  • arterial supply to the ascending colon is provided by the ielocolic and the ____ _____ artery. (sporcle.com)
  • the nerves to the ascending colon are derived from the _____ _____ plexus. (sporcle.com)
  • I had 12 inches of my ascending colon remover laparoscopically. (medicinenet.com)
  • Ascending colon, lamb 51481, day 4 p.i. (asm.org)
  • This space is defined by: The ascending colon and caecum laterally (further right). (wikipedia.org)
  • The mucosa forms the innermost layer that surrounds the lumen and is in contact with fecal matter stored in the colon. (innerbody.com)
  • Ulcerative colitis can affect any part of the colon (and other mucosa, such as the mouth), but when it affects the descending colon, it is called left-sided colitis. (wikipedia.org)
  • During distensions of the colon, arterial blood pressure and heart rate were kept constant by the withdrawal of blood and pacing of the heart, respectively. (elsevier.com)
  • Arterial supply to the colon comes from branches of the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). (colonoscopyandendoscopybilling.com)
  • L , descending-colon biopsies. (aacrjournals.org)
  • Multidimensional scaling of ascending- and descending-colon biopsies from HNPCC and non-HNPCC patients. (aacrjournals.org)
  • Sixty-eight ascending ( filled oval ) and descending ( open oval ) colon biopsies were clustered according to expression of 1336 genes. (aacrjournals.org)
  • Multidimensional scaling of ascending and descending fetal colon biopsies. (aacrjournals.org)
  • The descending colon is on the left side of the body (barring any malformations). (wikipedia.org)
  • many casual mentions of the left colon chiefly concern the descending colon. (wikipedia.org)
  • Ulcerative colitis can affect any part of the colon, but when it affects the descending colon, it is called left-sided colitis. (wisegeek.com)
  • the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon. (bioontology.org)
  • A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral Obturator Muscle," Case Reports in Surgery , vol. 2014, Article ID 128506, 5 pages, 2014. (hindawi.com)
  • Cancer in the transverse colon has a mixture of the symptoms experienced in right and left colon due to the semi-solid nature of stool in this segment. (livestrong.com)
  • The left side of the colon . (cancerqld.org.au)
  • forward displacement of the left dorsal colon is an uncommon cause of moderate colic in the horse. (thefreedictionary.com)
  • The descending colon laterally (further left). (wikipedia.org)
  • Colon cancer, like all cancers, is associated with a great tension that the person experienced and did not verbalize, kept well hidden. (flowsandforms.com)
  • Cancers in this part of the colon tend to go unnoticed for a long time. (livestrong.com)
  • In most cases of colon or rectal cancers, the cause or causes are unknown. (limamemorial.org)
  • Based on the tissues involved, colon cancers be further broken down into various types. (verywellhealth.com)
  • A case of mucinous adenocarcinoma of the colon presenting with psoas abscess," The Korean Journal of Gastroenterology , vol. 52, no. 2, pp. 120-123, 2008. (hindawi.com)
  • Histology section of the colon under a light microscope confirming an adenocarcinoma, which developed from the glandular epithelial tissue of the colon. (clinicaladvisor.com)
  • Adenocarcinoma is the most common type of colon cancer, accounting for approximately 96 percent of diagnoses. (verywellhealth.com)
  • Among the most common are ulcerative colitis , Crohn's disease, and colon cancer. (wisegeek.com)
  • Colon pain can also be a sign of other colon diseases, like Crohn's disease or IBS, so you should have your doctor check it out regardless. (wisegeek.com)
  • [1] It is possible to have medical problems with the descending colon including ulcers , cancer and Crohn's disease . (wikipedia.org)
  • There are several diseases associated with the descending colon. (wikipedia.org)
  • It is important to maintain good colon health, as there are several diseases associated with the descending colon. (wisegeek.com)
  • Maintaining good colon health is important because several diseases may negatively impact its function. (wisegeek.com)
  • Cancer of this portion of the colon is the most serious of the diseases. (wisegeek.com)
  • Abdominal pain may be a symptom of ulcerative colitis, a disease that is associated with the descending colon. (wisegeek.com)
  • In a 21-day study, we investigated the effects of AIEC strain UM146 inoculation on microbiota profile of the ileal, cecal, ascending and descending colon in a pig model of experimental colitis. (frontiersin.org)
  • The levels of Angiotensin II type 1 receptor (AT1), ACE, collagen type IV, transforming growth factor-β type 1 receptor (TGF-βR1), OB cadherin and α-smooth muscle actin in both descending colon and caecum were evaluated, using immunocytochemistry and confocal microscopy, in rats fed on high and low Na + diets (LS). (beds.ac.uk)
  • The colon is part of the large intestine, the final part of the digestive system. (healthline.com)
  • File:Digestive system diagram en.svg - Wikipedia, the free. (drug-purchase.info)
  • Your colon, also known as the large intestine, is part of your digestive system. (icdlist.com)
  • Colon cancer occurs with the presence of cancer cells in the colon or large intestine of the digestive system. (loyolamedicine.org)
  • The descending colon is a segment of the large intestine and is the third and penultimate segment of the colon. (innerbody.com)
  • The obstructed segment of the colon becomes markedly swollen and does not function as it should. (livestrong.com)
  • Second segment of the colon (middle section of the large intestine). (ikonet.com)
  • The proximal two-thirds of the transverse colon is perfused by the middle colic artery, a branch of superior mesenteric artery, while the latter third is supplied by branches of the inferior mesenteric artery. (colonoscopyandendoscopybilling.com)
  • The proximal colon differs from the distal colon in that it does not have amiloride-sensitive Na + conductance channels [ 4 ]. (beds.ac.uk)
  • A person can have colon cancer yet have no symptoms in the early stages. (wikipedia.org)
  • The symptoms of colon cancer vary according to location of the cancer within the colon as well as any spread outside the colon. (livestrong.com)
  • The lumen of the colon is smaller than that of its counterpart on the right and therefore the symptoms experienced are due to obstruction of the lumen. (livestrong.com)
  • It is important to monitor your digestive health and consult with your doctor if you experience a combination of any signs or symptoms of colon cancer. (loyolamedicine.org)
  • There are many potential symptoms of colon cancer , and what symptoms a person experiences depends on factors like the location and size of the cancer. (verywellhealth.com)
  • Keep in mind that some people experience no symptoms in the early stages of colon cancer. (verywellhealth.com)
  • What Are the Symptoms of Colon Cancer? (verywellhealth.com)
  • Undigested material, such as plant fiber, is passed next to the large intestine, or colon, mostly in liquid form. (limamemorial.org)
  • Your colon makes up the first five to six feet of your large intestine, thus making your colon the longest part of your large intestine. (loyolamedicine.org)
  • The colon is another term for the large intestine. (healthtap.com)
  • Like all parts of the gastrointestinal tract, the descending colon consists of four major tissue layers surrounding a hollow lumen. (innerbody.com)
  • on the posterior of the descending colon, the outermost layer is areolar connective tissue (known as adventitia). (innerbody.com)
  • The colon is held in place by peritoneum, a thin layer of tissue that supports the abdominal organs. (healthline.com)
  • The transverse colon hangs off the stomach, attached to it by a wide band of tissue called the greater omentum. (colonoscopyandendoscopybilling.com)
  • 0DUM87Z is a billable procedure code used to specify the performance of supplement descending colon with autologous tissue substitute, via natural or artificial opening endoscopic. (icdlist.com)
  • What that means is there may be evidence of inflamed tissue when the wall of the colon is measured but a normal colon is sometimes the same thickness. (healthtap.com)
  • The horse was treated with mineral oil (2lt) by stomach tube for two days to soften the feaces in the stenotic small colon. (clinicabagnarola.it)
  • The temporary or permanent channeling of the remaining open end of colon through the stomach wall and skin, where an ostomy appliance will attach to capture waste. (oreilly.com)
  • What I've always wondered is how somebody can go on with their life as normal after colon cancer surgery. (wisegeek.com)
  • We suspected a previous surgery characterized by extensive manipulation of the descending colon. (clinicabagnarola.it)
  • Colon cancer surgery at Loyola University Medical Center is rated as a high-performing speciality by U.S. News & World Report's on the 2020-21 Best Hospitals list. (loyolamedicine.org)
  • After surgery and lab test her colon cancer spread to her cervix. (medicinenet.com)
  • The small intestine connects to the colon where a valve regulates the movement of food. (anatomycorner.com)
  • The most common cause of small colon incarceration was strangulating lipoma. (elsevier.com)
  • The colon is wider than the small intestine but only about 6 feet long. (limamemorial.org)
  • is the first part of the colon after the small intestine. (limamemorial.org)
  • The examination of the entire length of the colon, up to its juncture with the small intestine, using a flexible tube that has a camera and a light source attached. (oreilly.com)
  • It is not extensive in the horse, in which it has an unusually long mesentery and is known as the small colon. (thefreedictionary.com)
  • It took the doctors and the hospital 3 months to figure out I didn't have gastritis , but stage 4 small colon cancer . (medicinenet.com)
  • Other imaging techniques used to test or diagnose colon cancer include specialized stool tests, magnetic resonance imaging (MRI) , computed tomography (CT or CAT) scans , tiny cameras implanted in swallowable pills (capsule endoscopy), and positron emission tomography (PET) or PET-CT scans. (loyolamedicine.org)
  • Co-localisation of cocaine- and amphetamine-regulated transcript peptide and vasoactive intestinal polypeptide in the myenteric plexus of the porcine transverse colon. (semanticscholar.org)
  • We studied the effects of a severely hypoproteic diet on the quantitative aspects of the myenteric plexus of the descending colon of young rats . (bvsalud.org)
  • Sadly, Tony Snow's death was no different, and his body was not even room temperature before the "alternative" medicine anti-chemotherapy ghouls were given voice at Mike Adam's repository of pseudoscientific lies and misinformation in an article entitled Tony Snow Dies Following Chemotherapy for Colon Cancer (opinion) , written by the lying webmaster of craziness himself, Mike Adams. (scienceblogs.com)
  • Now, former White House press secretary Tony Snow has died at the young age of 53 following chemotherapy treatment for colon cancer. (scienceblogs.com)
  • For reasons we will never know, Tony Snow chose the chemotherapy route in an attempt to treat his colon cancer, subjecting his body to systemic poisons that all the evidence shows produce absolutely no improvement in the five-year survival rate of colon cancer patients. (scienceblogs.com)
  • Recurrence and Cancer-Specific Death After Adjuvant Chemotherapy for Stage III Colon Cancer. (bioportfolio.com)
  • An ultrasound may be used to detect problems with the descending colon. (wisegeek.com)
  • Colon cancer is a disease in which malignant (cancer) cells form in the tissues of the colon.1. (drug-purchase.info)
  • The main difference between the response of myofibroblasts in descending colon pericryptal sheath from other tissues is the significant barrier to diffusion of macromolecules and NaCI in the colon generated by the fibronexus i.e. the multiple connections between cells and extracellular matrix [ 1 , 2 ]. (beds.ac.uk)
  • After flushing of the descending colon and abdominal cavity, the abdominal wall was sutured in two layers (fascia and skin) and the horse was put in the recovery box. (clinicabagnarola.it)
  • The location of the parts of the colon are either in the abdominal cavity or behind it in the retroperitoneum. (colonoscopyandendoscopybilling.com)
  • On the posterior side, the transverse colon is connected to the posterior abdominal wall by a mesentery known as the transverse mesocolon. (colonoscopyandendoscopybilling.com)
  • The paramesenteric gutters (paramesenteric recesses or infracolic spaces) are two spaces (or recesses) in the abdominal cavity between the colon and the root of the mesentery. (wikipedia.org)
  • Paracolic gutters are recesses between the abdominal wall and the colon. (wikipedia.org)
  • This activity outlines the etiology, epidemiology, clinical staging and stage-wise treatment of colon cancer. (nih.gov)
  • Adjuvant therapy could augment the chance of cure on high-risk patients with colon cancer. (nih.gov)
  • Oligo-metastatic, liver and lung, and local-recurrence patients with colon cancer are potential curable candidates with multimodality therapies. (nih.gov)
  • We speculated that the most likely condition needing laparotomy and manipulation of the descending colon was the surgical menagement of meconium impaction in the newborn foal. (clinicabagnarola.it)
  • Surgical removal of the displaced colon from its entrapment across the top of the gastrosplenic ligament is the only effective treatment. (thefreedictionary.com)
  • Palliative systemic therapy is reserved for non-surgical colon cancer candidates aiming to improve quality of life and prolong life expectancy. (nih.gov)