Tumors or cancer of the COLON.
A segment of the COLON between the RECTUM and the descending colon.
The segment of LARGE INTESTINE between the CECUM and the TRANSVERSE COLON. It passes cephalad from the cecum to the caudal surface of the right lobe of the LIVER where it bends sharply to the left, forming the right colic flexure.
The segment of LARGE INTESTINE between ASCENDING COLON and DESCENDING COLON. It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon.
Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS.
A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.
A pouch or sac opening from the COLON.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
A malignant epithelial tumor with a glandular organization.
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
A cell line derived from cultured tumor cells.
Hydrazines substituted with two methyl groups in any position.
Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)
Endoscopic examination, therapy or surgery of the luminal surface of the colon.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
A benign epithelial tumor with a glandular organization.
Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.
Tumors or cancer of the SIGMOID COLON.
Tumors or cancer of the RECTUM.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
The motor activity of the GASTROINTESTINAL TRACT.
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.
Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.
Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.
A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
The surgical construction of an opening between the colon and the surface of the body.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
Tumors or cancer of the CECUM.
Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.
Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Experimental transplantation of neoplasms in laboratory animals for research purposes.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.
A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.
High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.
The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
A reagent that is used to neutralize peptide terminal amino groups.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Agents that are used to stimulate evacuation of the bowels.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Transplantation between animals of different species.
Tumors or cancer of the INTESTINES.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.
Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Regular course of eating and drinking adopted by a person or animal.
A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Elements of limited time intervals, contributing to particular results or situations.
The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Hydrazines substituted by one or more methyl groups in any position.
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)
A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.
Opening or penetration through the wall of the INTESTINES.
A plastic operation on the esophagus. (Dorland, 28th ed)
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).
Dilatation of the COLON, often to alarming dimensions. There are various types of megacolon including congenital megacolon in HIRSCHSPRUNG DISEASE, idiopathic megacolon in CONSTIPATION, and TOXIC MEGACOLON.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)
DNA present in neoplastic tissue.
In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Tumors or cancer of the LIVER.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Uptake of substances through the lining of the INTESTINES.
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.
Endoscopic examination, therapy or surgery of the sigmoid flexure.
The contents included in all or any segment of the GASTROINTESTINAL TRACT.
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Short-chain fatty acids of up to six carbon atoms in length. They are the major end products of microbial fermentation in the ruminant digestive tract and have also been implicated in the causation of neurological diseases in humans.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.
Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
Antibodies produced by a single clone of cells.
The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Established cell cultures that have the potential to propagate indefinitely.
An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Antimetabolites that are useful in cancer chemotherapy.
Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
The normal process of elimination of fecal material from the RECTUM.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
Specially designed endoscopes for visualizing the interior surface of the colon.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
RNA present in neoplastic tissue.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Organic compounds which contain platinum as an integral part of the molecule.
An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
The action of a drug in promoting or enhancing the effectiveness of another drug.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.
Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)
A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC
The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).
A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)
A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).
A subcategory of mucins that contain SIALIC ACID.
Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.
Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.
A rod-shaped, gram-positive, non-acid-fast, non-spore-forming, non-motile bacterium that is a genus of the family Bifidobacteriaceae, order Bifidobacteriales, class ACTINOBACTERIA. It inhabits the intestines and feces of humans as well as the human vagina.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
The combination of two or more different factors in the production of cancer.
Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.
Tumors or cancer of the LUNG.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

Distinguishing right from left colon by the pattern of gene expression. (1/37)

Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis. These differences may reflect distinct biological characteristics of proximal and distal colonic mucosa, acquired in embryonic or postnatal development, that determine a differential response to uniformly distributed environmental factors. Alternatively, the differences in the epidemiology of proximal and distal CRCs could result from the presence of different procarcinogenic factors in the ascending versus descending colon, acting on cells with either similar or distinct biological characteristics. We applied cDNA microarray technology to explore the possibility that mucosal epithelium from adult proximal and distal colon can be distinguished by their pattern of gene expression. In addition, gene expression was studied in fetal (17-24 weeks gestation) proximal and distal colon. More than 1000 genes were expressed differentially in adult ascending versus descending colon, with 165 genes showing >2-fold and 49 genes showing >3-fold differences in expression. With almost complete concordance, biopsies of adult colonic epithelium can be correctly classified as proximal or distal by gene expression profile. Only 87 genes were expressed differently in ascending and descending fetal colon, indicating that, although anatomically relevant differences are already established in embryonic colon, additional changes in gene expression occur in postnatal development.  (+info)

Effects of nifedipine and nickel on plateau potentials generated in submucosal interstitial cells distributed in the mouse proximal colon. (2/37)

The effects of nifedipine and nickel ions (Ni2+), known inhibitors of L- and T-type voltage-gated Ca-channels respectively, were investigated on plateau potentials recorded from submucosal interstitial cells distributed in the mouse proximal colon. Plateau potentials were generated at a frequency of about 15 times min(-1) and were formed of two components. The primary component had an initial fast rate of rise with a transient potential (rate of rise, 130 mV/s; peak amplitude, 35 mV) and was followed by a secondary plateau component with a sustained potential (amplitude, 25 mV; duration, 2.6 s). Each cell from which recordings were made was injected with neurobiotin. Subsequent morphological examination with a confocal microscope indicated successful visualization of injected cells only in the presence of 18beta-glycylrhetinic acid (an inhibitor of gap junctional connections), suggesting that these cells were dye-coupled with surrounding cells. The cells injected with neurobiotin exhibited an oval-shaped cell body with bipolar processes and were distributed in the submucosal layer, suggesting that they were submucosal interstitial cells of Cajal (ICC-SM). The plateau potentials were not altered by 0.01 microM nifedipine, but were reduced in duration by 0.1 microM nifedipine, and abolished by 1 microM nifedipine. The rate of rise of plateau potentials, but not their amplitude, was reduced by Ni2+ (> 10 microM), with no significant alteration of the membrane potential. In the presence of 100 microM Ni2+, the plateau potentials were changed to a triangular form. Thus, the plateau potentials were formed by two types of voltage-gated channel current: the initial component was produced by a Ni2+-sensitive channel current and the plateau component by a nifedipine-sensitive current. The possible involvement of two different types of voltage-gated Ca2+-channels in the generation of submucosal pacemaker potentials was discussed.  (+info)

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/37)

1. Mechanisms involved in Ca(2+) sensitization of contractile elements induced by the activation of muscarinic receptors in membrane-permeabilized preparations of the rat proximal and distal colon were studied. 2. In alpha-toxin-permeabilized preparations from the rat proximal and distal colon, Ca(2+) induced a rapid phasic and subsequent tonic component. After Ca(2+)-induced contraction reached a plateau, guanosine 5'-triphosphate (GTP) and carbachol (CCh) in the presence of GTP further contracted preparations of both the proximal and distal colon (Ca(2+) sensitization). Y-27632, a rho-kinase inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization more significantly in the proximal colon than in the distal colon. 3. Y-27632 at 10 microm had no effect on Ca(2+)-induced contraction or slightly inhibited phorbol-12,13-dibutyrate-induced Ca(2+) sensitization in either proximal or distal colon. Chelerythrine, a protein kinase C inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization in the distal colon, but not in the proximal colon. The component of Ca(2+) sensitization that persisted after the chelerythrine treatment was completely inhibited by Y-27632. 4. In beta-escin-permeabilized preparations of the proximal colon, C3 exoenzyme completely inhibited GTP plus CCh-induced Ca(2+) sensitization, but PKC(19-31) did not. In the distal colon, C3 exoenzyme abolished GTP-induced Ca(2+) sensitization. It inhibited CCh-induced sensitization by 50 % and the remaining component was inhibited by PKC(19-31). 5. These results suggest that both protein kinase C and rho pathways in parallel mediate the Ca(2+) sensitization coupled to activation of muscarinic receptors in the rat distal colon, whereas the rho pathway alone mediates this action in the proximal colon.  (+info)

Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/37)

BACKGROUND: Because of their suggested link with microsatellite instability high colorectal cancers, right sided hyperplastic polyps (HPs) may differ from their distally located counterparts. This is highlighted by the recognition of a variant HP, termed sessile serrated adenoma (SSA), which predominates in the proximal colon. HPs displaying the morphological features now associated with SSAs have been shown to have altered expression of "cancer associated" markers, but no studies have investigated whether this is dependent on anatomical location of the polyps. AIMS: To evaluate morphological and functional features in right versus left sided HPs from patients without colorectal cancer with the aim of identifying distinguishing characteristics. METHODS: HPs originating in the proximal and distal colorectum were histochemically and immunohistochemically stained to evaluate a panel of markers related to proliferation and differentiation. In addition, a series of morphological features was evaluated for each polyp. RESULTS: Crypt serration, crypt dilatation, and horizontal crypt growth were more common among HPs from the right side, whereas histochemical factors including mucin changes, global methylation status, and expression of carcinoembryonic antigen were not significantly different. An age disparity was also seen between patients with right versus left sided lesions, with patients with right sided lesions being an average of more than 10 years younger than those with left sided lesions. CONCLUSIONS: These findings suggest that right and left sided HPs differ mainly in terms of growth regulation rather than cellular differentiation, implying that these lesions belong to a continuous spectrum of serrated polyps that differ quantitatively rather than qualitatively.  (+info)

A rare case of ascending colon actinomycosis mimicking cancer. (5/37)

BACKGROUND: Actinomycosis is a rare inflammatory disease caused by an anaerobic bacterium that can rarely affect the large intestine. CASE PRESENTATION: We present a rare case of a cecum and ascending colon actinomycosis in a 72 years old woman, mimicking clinically a malignant inflammatory tumor of the right colon. The patient complained of right lower quadrant pain. Although our first thought was a peri-appendiceal abscess, CT scan suggested a right colon tumor. The patient underwent a right colectomy and the histological examination of the specimen revealed colon actinomycosis. CONCLUSIONS: Preoperative diagnosis in colon actinomycosis is difficult to achieve. Treatment of choice is antibiotics administration. A review of the possible pathogenesis and therapeutic modalities is also presented.  (+info)

Treatment of resistant distal intestinal obstruction syndrome with a modified antegrade continence enema procedure. (6/37)

We report a case of a patient with CF who had a long history of recurrent distal intestinal obstruction syndrome. She had been treated with conventional treatment including gastrografin, n-acetyl cysteine, Klean prep and Picolax. She underwent a modified antegrade continence enema procedure. She currently irrigates her conduit every 2-3 days. She has had no further symptoms of distal intestinal obstruction syndrome.  (+info)

The retroperitoneal surface in distal caecal and proximal ascending colon carcinoma: the Cinderella surgical margin? (7/37)

BACKGROUND: Mesorectal margin tumour involvement is a predictor of local recurrence in rectal carcinoma and an indication for postoperative radiotherapy in suitable patients. However, the prevalence of non-peritonealised surgical margin involvement in ascending colon carcinoma is unknown. AIMS: To test the hypothesis that retroperitoneal surgical margin (RSM) tumour involvement occurs in distal caecal and proximal ascending colon carcinoma. METHODS/RESULTS: One hundred right hemicolectomy specimens, removed for adenocarcinoma of the caecum or proximal ascending colon, were studied. During routine specimen dissection, at least one additional tissue block was taken to include the tumour and the RSM. The tumour distance from the RSM was recorded. RSM tumour involvement was present in seven cases (7%). Direct (non-nodal) RSM tumour involvement (five cases) only occurred in posterior or circumferential tumours. CONCLUSIONS: RSM tumour involvement occurs within a considerable number of distal caecal and proximal ascending colon carcinomas. The rate of RSM tumour involvement identified here is similar to a previously published local recurrence rate of 10% in caecal carcinoma, suggesting that RSM tumour involvement may be a predictor of recurrence in these tumours. Therefore, patients with distal caecal or proximal ascending colon carcinoma and RSM tumour involvement may benefit from postoperative radiotherapy.  (+info)

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (8/37)

BACKGROUND: Despite the fact that the alimentary tract is part of the body's first line of defense against orally ingested xenobiotica, little is known about the distribution and expression of cytochrome P450 (CYP) enzymes in human colon. Therefore, expression and protein levels of four representative CYPs (CYP2C(8), CYP2E1, CYP3A4, and CYP3A5) were determined in human colon mucosa biopsies obtained from ascending, descending and sigmoid colon. METHODS: Expression of CYP2C, CYP2E1, CYP3A4, and CYP3A5 mRNA in colon mucosa was determined by RT-PCR. Protein concentration of CYPs was determined using Western blot methods. RESULTS: Extensive interindividual variability was found for the expression of most of the genes. However, expression of CYP2C mRNA levels were significantly higher in the ascending colon than in the sigmoid colon. In contrast, mRNA levels of CYP2E1 and CYP3A5 were significantly lower in the ascending colon in comparison to the descending and sigmoid colon. In sigmoid colon protein levels of CYP2C8 were significantly higher by ~73% than in the descending colon. In contrast, protein concentration of CYP2E1 was significantly lower by ~81% in the sigmoid colon in comparison to the descending colon. CONCLUSION: The current data suggest that the expression of CYP2C, CYP2E1, and CYP3A5 varies in different parts of the colon.  (+info)

Background Up to 50% of septic patients develop acute kidney injury (AKI). The pathomechanism of septic AKI is poorly understood. Therefore, we established an innovative rodent model to characterize sepsis-induced AKI by standardized colon ascendens stent peritonitis (sCASP). The model has a standardized focus of infection, an intensive care set up with monitoring of haemodynamics and oxygenation resulting in predictable impairment of renal function, AKI parameters as well as histopathology scoring. Methods Anaesthetized rats underwent the sCASP procedure, whereas sham animals were sham operated and control animals were just monitored invasively. Haemodynamic variables and blood gases were continuously measured. After 24 h, animals were reanesthetized; cardiac output (CO), inulin and PAH clearances were measured and later on kidneys were harvested; and creatinine, urea, cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) were analysed. Additional sCASP-treated animals were investigated
TY - JOUR. T1 - Inflammatory myoglandular colorectal polyps. T2 - A case series of nine patients. AU - Moriyama, T.. AU - Matsumoto, T.. AU - Hizawa, K.. AU - Tada, S.. AU - Fuchigami, T.. AU - Iwai, K.. AU - Yao, T.. AU - Iida, M.. PY - 2003/4/1. Y1 - 2003/4/1. N2 - Inflammatory myoglandular polyp is an uncommon benign colorectal polyp. We treated nine cases of histologically verified inflammatory myoglandular polyp. The polyps were identified as a pedunculated protrusion located in the distal part of the large intestine. On colonoscopy, eight polyps had a smooth, spherical, and hyperemic surface, accompanied by a patchy mucous exudate. Magnification endoscopy revealed a rugged surface composed of smooth nodules. These colonoscopic findings corresponded to hyperplastic glands with occasional cystic dilation and inflamed stroma with proliferation of smooth-muscle fibers. Inflammatory myoglandular polyp appears to be a distinctive clinical entity, with a unique appearance on colonoscopy.. AB - ...
TY - JOUR. T1 - The Malone antegrade continence enema procedure. T2 - Quality of life and family perspective. AU - Yerkes, Elizabeth B.. AU - Cain, Mark P.. AU - King, Shelly. AU - Brei, Timothy. AU - Kaefer, Martin. AU - Casale, Anthony J.. AU - Rink, Richard C.. PY - 2003/1/1. Y1 - 2003/1/1. N2 - Purpose: Since introducing the Malone antegrade continence enema (MACE) procedure into our practice, it has been our bias that social confidence and independence are significantly improved and satisfaction is overwhelmingly high. We objectively determine outcomes after the MACE to refine patient selection, and maximize the quality of perioperative counseling and teaching. Materials and Methods: An anonymous questionnaire was mailed to all patients who had undergone the MACE procedure within the last 4 years. Patient/parent satisfaction, impact on quality of life and clinical outcome were assessed with Likert scales. Demographic information, MACE specifics, preoperative expectations, and unanticipated ...
TY - JOUR. T1 - Extensive adenocarcinoma and large cell undifferentiated carcinoma of the lung treated with 5-FU, vincristine, and mitomycin C (FOMi). AU - Miller, T. P.. AU - McMahon, L. J.. AU - Livingston, R. B.. PY - 1980. Y1 - 1980. N2 - Fifty-six patients with extensive (52 with TNM stage III M1 disease and four with TNM stage III M0 disease) adenocarcinoma (46 patients) and large cell undifferentiated carcinoma (ten patients) of the lung were treated with combination chemotherapy consisting of 5-FU, vincristine, and mitomycin C (FOMi). The ten patients had not received prior chemotherapy. The overall response rate was 41% (23 of 56 patients). Four patients achieved a complete response and 19 achieved a partial response. In 12 patients the disease was stable. Response did not vary by cell type: adenocarcinoma, 18 of 43 patients (42%); large cell carcinoma, four of ten (40%); and alveolar cell carcinoma, one of three (33%). The response varied by initial performance status. For a Karnofsky ...
RESULTS: Continence was achieved in 98% of patients. Followup was 6 to 71 months (mean 28.4). There were 27 channel related complications (23%). Stomal stenosis occurred in 7 antegrade continence enema procedures (14%) within 1 to 10 months (mean 6.2) and in 9 continent bladder channels (13%), including 5 continent cutaneous vesicostomies, within 1 to 24 months (mean 9.4) after surgery. False passages occurred in 5 antegrade continence enema procedures (10%) within 1 to 13 months (mean 3.6) and in 4 continent catheterizable channels (6%) within 1 to 13 months (mean 6.5) after surgery. Of patients with stomal stenosis 50% were treated with surgical revision, while the remainder was successfully treated with dilation. Most false passages were managed by catheter drainage alone. Reasons for revision were contained perforation, colovesical fistula and inability to catheterize. Patient noncompliance appeared to have a role in stomal stenosis ...
Im Rahmen der Sepsis besitzt die Mikrozirkulation und insbesondere die intestinale Mikrozirkulation eine tragende Rolle in Bezug auf Organversagen und septischen Schock und ist somit ausschlaggebend für die Prognose septischer Patienten. Unser Anliegen bestand darin den antiinflammatorischen Einfluss der Antibiotika Linezolid und Tigecyclin auf die intestinale Mikrozirkulation septischer Ratten zu untersuchen. Linezolid, ein Vertreter der synthetischen Oxazolidinone, wird häufig in der Therapie der schweren gram-positiven Sepsis eingesetzt. Tigecyclin ist ein Vertreter der Glycylcycline, einer neuen Klasse von Antibiotika, und besitzt bakteriostatische Aktivität gegen ein breites Spektrum gram negativer und gram positiver Bakterien. Für unsere Untersuchungen nutzten wir das Colon ascendens Stent Peritonitis (CASP) Modell. Die Beurteilung der intestinalen Mikrozirkulation erfolgte mittels Intravitalmikroskopie. Linezolid führte zu einer statistisch signifikanten Verbesserung der intestinalen
Video articles in JoVE about acute kidney injury include Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish, Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice, Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury, Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury, Intravenous Microinjections of Zebrafish Larvae to Study Acute Kidney Injury, Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney, Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration, Kidney Regeneration in Adult Zebrafish by Gentamicin Induced Injury, Isolation of Double Negative αβ T Cells from the Kidney, Techniques to Assess Kidney Function in Mouse Models of Glomerular Disease, Use of a Hanging-weight System for Isolated Renal Artery Occlusion, Phenotypic Characterization of Macrophages from Rat Kidney
Background Up to 50% of septic patients develop acute kidney injury (AKI). The pathomechanism of septic AKI is poorly understood. Therefore, we established an innovative rodent model to characterize sepsis-induced AKI by standardized colon ascendens stent peritonitis (sCASP). The model has a standardized focus of infection, an intensive care set up with monitoring of haemodynamics and oxygenation resulting in predictable impairment of renal function, AKI parameters as well as histopathology scoring. Methods Anaesthetized rats underwent the sCASP procedure, whereas sham animals were sham operated and control animals were just monitored invasively. Haemodynamic variables and blood gases were continuously measured. After 24 h, animals were reanesthetized; cardiac output (CO), inulin and PAH clearances were measured and later on kidneys were harvested; and creatinine, urea, cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) were analysed. Additional sCASP-treated animals were ...
The ascending colon is the part of the colon located between the cecum and the transverse colon. The ascending colon is smaller in calibre than the cecum from where it starts. It passes upward, opposite the colic valve, to the under surface of the right lobe of the liver, on the right of the gall-bladder, where it is lodged in a shallow depression, the colic impression; here it bends abruptly forward and to the left, forming the right colic flexure (hepatic) where it becomes the transverse colon. It is retained in contact with the posterior wall of the abdomen by the peritoneum, which covers its anterior surface and sides, its posterior surface being connected by loose areolar tissue with the iliacus, quadratus lumborum, aponeurotic origin of transversus abdominis, and with the front of the lower and lateral part of the right kidney. Sometimes the peritoneum completely invests it and forms a distinct but narrow mesocolon. It is in relation, in front, with the convolutions of the ileum and the ...
Anomalies of the peritoneum and the colon are quite common. Some of these anomalies can disturb the normal digestive and absorptive functions of the intestine and the others might result in formation of volvulus or impede the blood supply of the intestine. We report a rare, combined variation of peritoneum and ascending colon. In a 70-year-old male cadaver, the greater omentum was very small and extended only for about an inch below the transverse colon. From its lower end, a fibrous band extended to the right wall of the upper part of ascending colon. There was a deep constriction on the right wall of the ascending colon at the site of attachment of the fibrous band. The ascending colon was grossly dilated. Further, the ascending colon was mobile and presented a small ascending mesocolon along its left edge. We discuss the possible embryological basis and clinical and surgical relevance of the case.. Keywords: Peritoneum, Digestive system, Ascending colon, Peritoneum, Omentum ...
A 69 year old lady attended for a colonoscopy under the UK Bowel Cancer Screening Programme having been found to be FOB ve using the Guaiac test. A large LST-G was found in the ascending colon ...
TY - JOUR. T1 - Microvascular permeability changes in ischemia/reperfusion injury in the ascending colon of horses.. AU - Henninger, D. D.. AU - Snyder, J. R.. AU - Pascoe, John. AU - Dilling, G. W.. PY - 1992/10/15. Y1 - 1992/10/15. N2 - The normal microvascular permeability of the ascending colon in horses and the microvascular permeability of that segment after ischemia and reperfusion were investigated. Microvascular permeability was estimated by the ratio of lymphatic protein to plasma protein concentration (Cl/Cp) at high lymph flow rates in 8 adult horses in 2 equal groups: normal and ischemic (2-hour period). Lymphatic flow rates and lymph and plasma protein concentrations were determined. Intestinal biopsy specimens were obtained at the end of each experiment. Flow independent values were selected and compared by one-way ANOVA, and the mean and SEM of these values were determined. The mean Cl/Cp ratios for the flow independent part of each data set were as follows: normal = 0.36 +/- ...
Several diseases can affect the ascending colon, or first part of your large intestine. If youre experiencing pain in this area, heres what you should know.
The ICD-10 Code C18.2 is the code used for Malignant neoplasm of ascending colon .An alternative description for this code is Malignant neoplasm of ascending ...
There is dilation of Jejunal (3.3 cms) and ileal (4.7cms) loops . Caecum (8.3 cms), ascending colon proximal ascending colon also appears to be dilated. Wall thickening noted in mid transverse colon with few pericolonic nodes. Suspicious small Polypoidal lesions also noted in hepatic flexure region. The descending colon, sigmoid colon and rectum are collapsedDiscussionThe MDCT Features were suggestive of intestinal obstruction due to growth at mid transverse colon with pericolonic nodes. Patient underwent laprotomy , confirming the diagnosis. 64 SLICE MDCT provides exquiste resolution and depiction of the pathology. The transition zone of the obstruction and cause for the ostruction can be easily diagnosed. ...
The porcelain throne was actually invented in the UK as a way to civilize such a barbaric act as defecating. Previous to about the late 18th and early 19th centuries, our ancestors didnt have toilets and were pooping by the most natural way our bodies were meant to poop: by SQUATTING. In ancient civilizations, the only people sitting to poop were royalty and the handicapped. Squatting was considered too lowly and an act of the common folk. Sitting was a much more dignified posture as compared to the animalistic squatting position. The problem that arose is that the sitting posture was more for the satisfaction of the ego rather than the function of the body. If one looks at the anatomy of the human colon, what youll find is that humans are the only species where our bowels have to move upward against gravity. This is evident where the small intestine transitions into the large intestine by the ascending colon (as an anatomy refresher the ascending colon goes up on the right lower front ...
This is where fermentation takes place. The person who experiences problems in this area has difficulty deciding whether to keep or let go. Fermentation happens
Modification #1. (To follow Step #4 if barium has not reached the ascending colon.) Turn the patient 360° in each direction. When the patient is again prone, take another look. If barium is now in the ascending colon, proceed to Step #5; if not, go to Modification #2. (NOTE: Do not insufflate additional air at this point, as it will likely produce an air-lock in the cecum ...
Diagnosis Code D3A.022 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
A 67-year-old man who presented with a bloody stool was diagnosed with ascending colon cancer. He had previously experienced thoracic and abdominal aortic dissections, which were treated with thoracic and abdominal aortic grafts and superior mesenteric artery revascularization. We performed a laparoscopic right hemicolectomy with a D3 lymph node dissection. During the laparotomy, we identified the superior mesenteric artery and an enlarged anterior superior pancreaticoduodenal artery. Injury to the latter artery could lead to severe ischemia in multiple organs; therefore, it was crucial to identify the primary feeding artery and vascular anatomy before and during surgery ...
PET demonstrated a large mass with intense FDG uptake in the right hilum corresponding to the patients known carcinoma. Peripheral to the large mass is a wedge-shaped area of mildly increased FDG uptake due to the adjacent post-obstructive pneumonitis as evidenced in the CT of the chest. In addition, there is intense FDG activity in the abdomen and pelvis conforming to small bowel loops in the initial PET imaging. Further delayed PET imaging of the abdomen and pelvis showed progression of the FDG into the distal ileum, cecum and proximal ascending colon. Mild FDG uptake in the left chest wall is of uncertain significance. This may be due to prior trauma, but there is no focal abnormality identified on CT in that region ...
Morning, Kathy -. Has your mom had a follow-up CT Scan to see if they can visualize anything that might be causing pain? If your mom had a hemicolectomy where the surgeon removed a portion of the pipe and sewed the two clean edges together, there is sometimes a significant size difference. This often leads to gas which can be quite painful. Scar tissue can also cause pain as can adhesions which result from improper healing after surgery. In short, there are tons of possible causes for the pain. Pain is a sign that there is something not right and your moms doctor should be aggressively looking for the cause. If s/he isnt, I suggest finding another doc who will.. As for dehydration - its very very normal. The main culprit is diareha, but - again - if your mom has had a hemicolectomy and they removed some/all of her ascending (right) colon, then that can cause problems, too. The ascending colons main function is to remove and purify water from the waste stream and send it back into the body. ...
TY - JOUR. T1 - Ureteral replacement with reconfigured colon substitute. AU - Pope, John. AU - Koch, Michael. PY - 1996/5. Y1 - 1996/5. N2 - Purpose: Upper ureteral defects are often too extensive to repair by direct anastomosis or with use of a bladder flap. Ureteral substitution may be the only remaining alternative to restoring urinary drainage from the kidney to the bladder. This effect is usually achieved by interposing a segment of small bowel between the proximal collecting system and bladder. If ileum is not available other substitution alternatives must be sought. Materials and Methods: We report a new technique in which a tube constructed from a small piece of ascending colon was used to replace a large ureteral defect. Results: Excellent short-term results were achieved by replacing the strictured ureteral segment with a reconfigured colon segment as shown by symptomatic and radiographic improvement. Conclusions: A reconfigured colon segment can be used for ureteral reconstruction in ...
Ascending Colon Membrane Lysate Catalog Number: XBL-10523 By Type: Tissue Species: Human Diagnosis: Normal Tested Applications: WB Size: 0.1 mg ...
The Colon Care Centre does not promote water fasts for the obvious reason that we want the body to be eliminating toxins from the liver, kidneys, lymphatic system, skin and colon whilst you are preparing for your ultimate in colon cleansing. Water fasting shuts down the bodys eliminating process holding back the toxins because it is undergoing a negative feedback reaction which means the body will not generally respond until there is a variation from the normal.. While you are juice fasting we are promoting total alkalinity to feed the cells whilst responding in lowering acidity, candida and cleansing each cell in the body.. During the 1st, 2nd, 3rd day of your vegetable juice fasting your body is eliminating toxins and the bowels own peristalsis is being activated giving great results before the colonic treatment.A colonic treatment is to be performed on the 4th day of your juice fasting. We support your detox by increasing the hydration within the descending , transverse and ascending colon ...
Top 10 cancers for NM_000143 (Homo sapiens, RefSeq): tongue, squamous cell carcinoma, NOS, angiosarcoma of liver, liver, hemangioma, NOS, cardia, adenocarcinoma, NOS, metastatic, liver, hepatocellular carcinoma, NOS, metastatic, sigmoid colon, adenoma, NOS, unstated behavior, colon, neoplasm, malignant, unstated behavior, ascending colon, carcinoma, NOS, breast, adenocarcinoma, NOS, metastatic, cecum, carcinoma, NOS
With patient lying supine, the evaluation with the duodenum with superior frequency ultrasound duodenography is executed with seven.five MHz probe positioned in the correct upper abdomen, and central epigastric successively; for high frequency ultrasound colonography, the ascending colon, is examined with start line normally midway of an imaginary line managing from your iliac crest for the umbilicus and proceeding cephalid throughout the appropriate mid abdomen; with the descending colon, the assessment begins through the still left higher abdomen proceeding caudally and traversing the still left mid abdomen and left reduce abdomen, terminating with the sigmoid colon in the lower pelvic area. Shade movement Doppler sonography is utilized to examine the localization of lesions in relation to vessels. All measurements of diameter and wall thickness are performed with developed-in application. Measurements are taken concerning peristaltic waves.[45 ...
With affected person lying supine, the examination of the duodenum with significant frequency ultrasound duodenography is executed with 7.five MHz probe positioned in the appropriate upper abdomen, and link central epigastric successively; for top frequency ultrasound colonography, the ascending colon, is examined with start line generally halfway of an imaginary line jogging from the iliac crest into the umbilicus and continuing cephalid through the suitable mid abdomen; to the descending colon, the evaluation commences through the remaining higher abdomen proceeding caudally and traversing the remaining mid abdomen and left lessen abdomen, terminating in the sigmoid colon during the reduce pelvic region. Coloration flow Doppler sonography is employed to look at the localization of lesions in relation to vessels. All measurements of diameter and wall thickness are executed with developed-in software program. Measurements are taken between peristaltic waves.[forty five ...
An 18-year-old male patient presented with a cold abscess affecting his wrist and subsequently developed diarrhoea. The DCBE erect view shows contraction of the ascending colon and, in particular, the caecum. The ileocaecal valve is irregularly contracted (arrows) and the distal 2cm of the terminal ileum is irregular in outline, with at least one short sinus track. Acid-fast bacilli were isolated from the cold abscess and from the colon ...
Lynch syndrome (LS), former known as Hereditary Non Polyposis Colorectal cancer (HNPCC), accounts for 3-5% of all colorectal cancers (CRC) and is inherited in an autossomal dominant fashion. This syndrome is characterized by early CRC onset, high incidence of tumors in the ascending colon, excess of synchronous and metachronous tumors, and accelerated transition adenoma-carcinoma (2-3 years). Nowadays, LS is regarded of patients who carry deleterious germline mutations in one of the five Mismatch repair genes, such as MutL homolog 1 (MLH1), MutS homolog 2 (MSH2), MutS homolog 6 (MSH6), post-meiotic segregation increased 1 (PMS1) or post-meiotic segregation increased 2 (PMS2). In order to characterize Brazilian patients suspect for LS, we assessed the frequency of germline point mutations in MSH6, PMS1 and PMS2 in patients negative for point mutations in MLH1 and MSH2 by capillary sequencing. We also assessed chromosomal deletions in MLH1 and MSH2 and MSH6 generating a complete characterization ...
The life cycle of the parasites are so interesting. The pinworm life cycle is pretty simple. They are ingested by fecal-oral contact, the eggs hatch in the duodenum, the larvae molt a couple of times on their way down to the cecum and ascending colon where they mate. Gravid females migrate to the anus at night where they release their eggs and maybe cause some pruritis ani. Superinfection may occur from there and the scotch-tape test may catch them for diagnosis. You guys nailed it, the treatment is mebendazole 100mg po once ...
Radiates from ear, lumbago, radiation in appendages, bladder, pelvis & groin, pain inner knee, deep lumbago, sacroiliac syndromes, servo-steering of osmosis, dialysis, turbulence & thermal, sleep & waking state, arteries.. Ascending colon.. [toothbooks]. ...
TY - JOUR. T1 - Aorta ascendens álaneurysma mély hypothermiában keringés leállítással végzett sikeres mütéte.. AU - Szabó, Z.. AU - Rényi-Vámos, F.. AU - Bodor, E.. AU - Kalmár, I.. AU - Gyöngy, T.. AU - Papp, L.. PY - 1984/12/9. Y1 - 1984/12/9. UR - http://www.scopus.com/inward/record.url?scp=17644432166&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=17644432166&partnerID=8YFLogxK. M3 - Article. C2 - 6514347. AN - SCOPUS:17644432166. VL - 125. SP - 3053. EP - 3056. JO - Orvosi Hetilap. JF - Orvosi Hetilap. SN - 0030-6002. IS - 50. ER - ...
Yesterday, Judge Gilstrap of the Eastern Division of Texas issued a preliminary injunction Order (an anti-antisuit-injunction or, more properly, an
Lymph node metastasis to the iliac or inguinal region of colon cancer is extremely rare. We experienced a case of ascending colon cancer with synchronous isolated right external iliac and inguinal lymph node metastases but without any regional lymph node metastasis. An 83-year-old woman was admitted to our hospital due to anemia. Colonoscopy and computed tomography revealed an ascending colon cancer and also right external iliac and inguinal lymph node swelling. Further examination by F-deoxyglucose positron emission tomography strongly suggested that these lymph nodes were metastatic. Right hemicolectomy with lymph node dissection along the superior mesenteric artery, and right external iliac and inguinal lymph node dissection were performed. Histological examination revealed that both lymph nodes were metastasized from colon cancer, and there was no evidence of regional lymph node metastasis. The patient has shown no sign of recurrence at 27 months after surgery.
Review question. We reviewed the evidence about the effectiveness and safety of different treatments for distal intestinal obstruction syndrome (DIOS) in children and adults with cystic fibrosis.. Background. Cystic fibrosis is a common, life-limiting, inherited disease. One of the main features of cystic fibrosis is the thick, sticky mucus produced by many organs including the lungs, pancreas and intestine. DIOS occurs when mucus in the intestine combines with faeces and builds up to produce a mass. This mass can partially or completely block the intestine and cause symptoms such as vomiting, severe abdominal pain and a swollen stomach (abdominal distension). Once a diagnosis of DIOS has been made, the goal of therapy is to relieve the complete or partial blockage and ultimately prevent the need for any surgical intervention.. Search date. The evidence is current to: 10 June 2018.. Trial characteristics. The review included one trial with 20 people with cystic fibrosis who were aged between 7.1 ...
An antegrade continence enema, or ACE, is a different way to give an enema. Enemas can help someone poop if they become constipated or have another problem moving their bowels.
Contents: General Principles. Preparation for colorectal surgery .Safety and positioning in the operating room. Access to abdominal cavity - open. Access to abdominal cavity - laparoscopic. Access to abdominal cavity - hand-assisted laparoscopic surgery. Single incision laparoscopic-assisted colectomy. Access to the abdominal cavity: natural orifice transluminal endoscopic surgery. Anastomotic technique - suture. Anastomotic technique - stapled. Specimen handling. Proctology. Office/outpatient set up. Proctosigmoidoscopy. Flexible endoscopy. Treatment of uncomplicated haemorrhoids. Excision of perianal thrombosis. Open hemorrhoidectomy. Closed hemorrhoidectomy. Stapled hemorrhoidopexy. Perianal sepsis. Anal fistula. Rectovaginal fistula repair. Anal fissure. Anoplasty. Perianal condyloma and anal intraepithelial neoplasia. Perianal skin and anal cancer Pilonidal disease. Stomas. Ileostomy. Colostomy. Stoma closure. Antegrade continence enema procedure in children. Antegrade continent enema ...
Objectives: Various definitions for distal intestinal obstruction syndrome (DIOS), meconium ileus equivalent, and constipation in patients with cystic fibrosis (CF) are used. However, an unequivocal definition for DIOS, meconium ileus equivalent, and constipation is preferred. The aims of this study were, therefore, to seek consensus on the definitions for DIOS and constipation in patients with CF and to determine the incidence, characteristics, and treatment of DIOS in a cohort of paediatric patients with CF. Methods: During the 2005 European Society for Paediatric Gastroenterology, Hepatology, and Nutrition meeting in Porto a group of paediatric gastroenterologists discussed the definition of DIOS and constipation in CF. Subsequently, all patients younger than or equal to 18 years with complete DIOS according to the definition agreed upon and diagnosed during the years 2001 to 2005 in 8 CF centres were studied. Results: Distal intestinal obstruction syndrome was defined as an acute complete or ...
By Patel, Vijaykumar G Rao, Arundathi; Williams, Reginald; Srinivasan, Radha; Et al Acute epiploic appendagitis (EA) is a rare and often misdiagnosed cause of acute abdominal pain. Though a benign and often self- limiting condition, EAs ability to mimic other disease processes makes it an important consideration in patients presenting with acute abdominal symptoms. Careful evaluation of abdominal CT scan findings is crucial in the accurate diagnosis of epiploic appendagitis, thus avoiding unnecessary surgical intervention. We report a case of a 29-year-old male presenting with a two day history of generalized abdominal pain. Physical exam revealed a diffusely tender abdomen with hypoactive bowel sounds. The patient had a leukocytosis of 18,000 and abdominal CT scan revealed right lower quadrant inflammatory changes suggestive of acute appendicitis. Laparoscopic exploration revealed an inflamed gangrenous structure adjacent to the ileocecal junction. Pathologic evaluation revealed tissue ...
When done properly, coffee enemas can be an excellent compliment to any healing program. Coffee enema procedure - detox liver support
Hellenic Society of Gastroenterology. Annals of Gastroenterology.Journal part.Scientific article.Article.2012 . Creators: Karmiris, Konstantinos, Tribonias, Georgios, Kontopodis, Nikolaos, Konstantinidis, Konstantinos, Voudoukis, Evangelos, Miliadis, Odysseas, Paspatis, Gregorios A., Spiridakis, Konstantinos G, Georgiou, Georgios, Psilakis, Konstantinos.A 61-year-old male on anticoagulant therapy underwent an endoscopic multiple colonpolypectomy in our Department according to established procedures. Several days later hedeveloped an intramural colonic hematoma, which burst into the peritoneal cavity leading tofatal intra-peritoneal hemorrhage. Herein we present the case and discuss the causative roleof the anticoagulant therapy but also of the endoscopic procedure per se.Keywords colonoscopy, intramural colonic hematoma, intra-peritoneal hemorrhageAnn Gastroenterol 2012; 25 (2): 265-267. Types: info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion
Free, official information about 2011 (and also 2012-2015) ICD-9-CM diagnosis code 209.53, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
Channing rescues Jupiter, who is now free to live in a palace and rule the Universe, but she decides to go back home and scrub commodes, because its a little late in the movie to start pretending shes smart. On the bright side, her annoying family unexpectedly turns nice and gives her a telescope so shell get murdered by Russian gangsters, and Channing gets his wings, just like Clarence in Its a Wonderful Life, and promptly uses them to make out in mid-air with Jupiter, just like Clarence did with George Bailey. So everybody got what their hearts desire, I guess, except me. I wanted a thrilling yet thoughtful science fiction epic in the vein of The Matrix. What I got was the worlds longest commercial for the Chlorox Toilet Wand ...
Epiploic appendagitis (EA) is a rare cause of focal abdominal pain in otherwise healthy patients with mild or absent secondary signs of abdominal pathology. It can mimick diverticulitis or appendicitis on clinical exam. The diagnosis of EA is very infrequent, due in part to low or absent awareness among general surgeons. The objective of this work was to review the authors experience and describe the clinical presentation of EA. All patients diagnosed with EA between January 2004 and December 2006 at an urban surgical emergency room were retrospectively reviewed by two authors in order to share the authors experience with this rare diagnosis. The operations were performed by two surgeons. Pathological examinations of specimens were performed by a single pathologist. A review of clinical presentation is additionally undertaken. Ten patients (3 females and 7 males, average age: 44.6 years, range: 27-76 years) were diagnosed with symptomatic EA. Abdominal pain was the leading symptom, the pain being
Therapy of epiploic appendagitis is a topic of some controversy. It is described by some authors as a self-limiting condition with patients recovering in less than 10 days with oral anti-inflammatory medication [22]. Most of the surgical literature underlines the benign course of disease and favors a conservative therapy regiment. This is a widely applied form of therapy which is practiced with success. However, we have observed that there is a tendency of recurrence in conservatively treated patients. Four of ten patients in this study (40%) already had the same pain at the same localization, for two days on average, four weeks before presenting to the emergency department. This cannot be taken as decisive evidence that EA recurs if not treated surgically. Nevertheless it arouses suspicion that conservative forms of therapy might have a tendency for recurrence and surgical interventions should be considered. In the authors personal opinion surgical therapy is favorable to prevent recurrence, ...
Epiploic appendagitis is usually seen in middle-aged men with a history of diabetes. They are an important cause of abdominal pain since they are managed with supportive care only and do not require a laparotomy.
Appendagitis epiploic - What is epiploic appendagitis? The great pretender! Epiploic appendices are tear-drop shaped projections of fat that are attached to the outer wall of the large intestine. They have a propensity to twist, which may cut-off its blood supply and cause acute pain. This is a self-limiting condition that does not require any treatment. When this occurs on the right side, it is often mistaken for appendicitis, unless a skilled radiologist finds this on ct.
Reduced size model of a human colon showing ileum, caecum, ascending colon, transverse colon, descending colon, sigmoid colon and rectum.
You will appreciate the convenience of having the Life/form® Enema Administration Simulator to teach enema procedures. Use it for group demonstrations and practice sessions of any size. Each student can realistically practice administering an enema using this lifelike model. The standard enema procedures can be perform
Caecal volvulus is an infrequent clinical condition caused by an axial twist of ascending colon, caecum and terminal ileum around the mesenteric pedicle. This article presents the case of a 16 year old African male from Kenya who presented to the emergency department with acute onset right sided lower abdominal pain diagnosed intra-operatively as caecal volvulus. The rare nature of the condition, the need for a high index of suspicion and surgical management are highlighted.
Peristalsis is a rhythmic and symmetrical contraction and relaxation of the colon to move waste from the body. Often, due to dehydration, over-use of laxatives, stress, or Colitis, Crohns or IBS, this movement doesnt work in the way it should.. Learning the 9-Part Abdominal Exercises can restore this function resulting in regular bowel movements, release of gas and abdominal cramping, and relief from debilitating symptoms.. The colon has different segments: the cecum, the ascending colon, the hepatic angle, the transverse colon, the splenic angle, the descending colon, and the sigmoid colon. In the 9-Part Abs, one massages each segment separately in order to enable the parts to work seamlessly as a whole.. ...
Top 10 tissues for NP_689551 (Homo sapiens, RefSeq): colonic gland (crypt), caecum (cecum), ascending colon, proximal colonic mucosa, descending colon, descending colonic mucosa, transverse colon, ascending colonic mucosa, distal colonic mucosa, sigmoid colon
This medical exhibit pictures an anterior (front) view of the normal anatomy of the large and small intestines. Labels are provided for the duodenum, ascending colon, terminal ileum, cecum, transverse colon, descending colon, sigmoid colon and rectum. This illustration also shows the liver and stomach.
This medical exhibit pictures an anterior (front) view of the normal anatomy of the large and small intestines. Labels are provided for the duodenum, ascending colon, terminal ileum, cecum, transverse colon, descending colon, sigmoid colon and rectum. This illustration also shows the liver and stomach.
For a longer-form examination of these data, click here.. A retrospective analysis from a large, federally funded clinical trial finds that the location of the primary tumor within the colon predicts survival and may help inform optimal treatment selection for patients with metastatic colorectal cancer. The study was featured in a press briefing today and will be presented by Venook et al on Sunday, June 5, at the 2016 ASCO Annual Meeting in Chicago (Abstract 3504).. The data show that patients whose primary tumors originate on the left side of the colon (the descending colon, sigmoid colon, and rectum) survive significantly longer than those whose tumors originate on the right side (the cecum and ascending colon).. While previous studies had suggested that tumor location may impact clinical colorectal cancer outcomes, the effect we observed in this analysis appears to be far greater than we expected, said lead study author Alan P. Venook, MD, Professor of Medicine at the University of ...
Colon lavement - Radio-Anatomie - Titre: Radio-Anatomie - Colon lavementDiagnostic: Colon lavementHôpital: HUGDépartement: AnatomieDate: 21.03.2003ID: 3460Chapitre: AbdomenDescription: DESCRIPTION: 1) Caecum (Coecum) 2) Côlon ascendant(Colon ascendens) 3) Angle colique droit (Flexura coli dextra) 4)Côlon transverse (Colon transversum) 5) Angle colique gauche(Flexura coli sinistra) 6) Impression splénique et bord de la rate7)... - 1211492105 - Geneva University Hospital
In the CASP model, a stent is surgically inserted into the ascending colon of experimental mice. This leads to a persistent leakage of the gut with defined size and - depending on the stent size - to a lethal or sublethal polymicrobial sepsis. We performed 16 G CASP operations in CCR4 KO mice or wild-type (WT) controls. For ex vivo analysis, organ expression of CCR4 and its ligands, CCL17 and CCL21 were detected by real-time PCR. The bacterial loads of various organs were analyzed. Additionally, tissue cytokine levels were detected by cytometric bead array. Finally, adoptive transfer experiments from CCR4 KO mice to WT animals with or without CASP-induced peritonitis were performed. ...
PICTURES IN DIGESTIVE PATHOLOGY. Anorectal melanoma associated with colonic metastasis. Melanoma anorrectal asociado a metástasis colónicas. Macarena Fernández-Albornoz, Joaquín Irarrázaval-Espinoza, Andrés Larach-Kattan and Leonardo Espíndola-Silva. Hospital Militar. Santiago, Chile. Case report. A 67-year-old female patient with no medical history presents with pain and increased volume in her right lower limb for the last three weeks. She is admitted with a diagnosis of right-side iliac-femoral-popliteal deep venous thrombosis and bilateral pulmonary thromboembolism. She developed rectorrhagia following anticoagulation. Colonoscopy revealed an exophytic, mamillated, friable, anteriorly ulcerated lesion from the anal margin to the mid rectum (Fig. 1), two lesions with similar characteristics in the ascending colon, and three such lesions at the ileocecal valve (Fig. 2). Histopathology and immunohistochemical studies are consistent with melanoma. Abdominal and pelvic CT and MRI scans ...
Large LST of the ascending colon. Previous biopsies show adenoma with low grade displasia. Author: Dr. Franco Orellana, Chile. ...
Additionally, the vessels in the same manoeuvre with a slight structural resemblance to the massive infiltration of neighbour tissues, respect of persistent is chemotherapy, which is available for sex uncomfortable environment for sex. *** sexual solutions when the urologist also said to have sex while under the microscope. Studies made with no significant safety issues noted during infusion and the parents should be taken on an apprehensive child. This volume increases the force of contraction of male lower urinary tract may demon- at the introitus by labial adhesions, resulting in sedation as an antidepressant, although a cord structures. They were treatment may reduce renal compres- sion more quickly, followed by 2002 protocol into low-risk, intermediate-risk and chemotherapy on dna. How should i buy. Inhibit the absorption from the truth, graham was now more confused than ever. (part of rectum and the descending colon ascending colon sigmoid colon figure 5.12 sites of obstruction by ...
small and large intestine anatomy. this image shows the anatomy of the git from the small intestine to the anus.displaying their position and relation to each other and to the rest of the body. showing: 1. esophagus 2. liver 3. stomach 4. small intestine 5. ascending colon 6. descending colon 7. tr
Proper digestion has the ability to make or break ones holistic wellness. Digestion is the nucleus of our energy regulation, and we dont operate well when were feeling sluggish, bloated, or queasy. Optimal digestion leads to regular elimination, which is the bodys natural way of flushing out toxins and waste. At the risk of TMI, lets just say that without regular elimination were left in a very yucky, heavy state!. As yogis, we know especially well how uncomfortable it is to practice when full, bloated, queasy or constipated. So here are three simple, easy ways yoga can improve your digestion.. 1. Apanasana. Apanasana, knees hugged to belly, is known as the wind-relieving pose. Hugging the right knee into the belly massages the ascending colon, while hugging the left knee in massages the descending colon. Try this simple pose for improved digestion:. Come to lie on the back. Settle into your yoga mat or wherever you are. Place your feet to the floor, directly beneath the knees. On an ...
Cancers on the appropriate side of the massive intestine (ascending colon and cecum) tend to be exophytic, which is, the tumor grows outwards from a person location while in the bowel wall.The higher prerequisite for observe-up colonoscopy that has a FOBT programme does have to have a large amount of means to be put into gastroenterological solutio… Read More. ...
The first sagittal plane ( Fig. 214.1 ) through the far right side of the body shows the oblique muscles of the abdominal wall (28), sections of the ribs (51) with the intercostal muscles (25), and a section of the scapula (53) with the subcostal muscle (18) and infraspinatus muscle (20). The next image in a slightly more medial plane ( Fig. 214.2 ) displays the right lobe of the liver (122) and a section of the ascending colon (142). The numerical labels are keyed to the Thoracic and Pelvic Diagrams fold-out key on the back cover flap of this book.. ...
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Epipterygium Lindb., Öfvers. Förh. Kongl. Svenska Vetensk.-Akad. 19: 603. 1862. Plants small, dull or glossy, pale, glaucous-green to pinkish or reddish green in loose tufts; stems forked or simple; rhizoids sparse, reddish brown, lightly papillose. Leaves dimorphic, lateral leaves in 2-3 rows, obovate to broadly elliptic, acute, sometimes decurrent, dorsal leaves in 1-3 rows, smaller and narrower than the lateral leaves, lanceolate to linear-lanceolate acute to shortly acuminate; margins bordered or elimbate, plane, entire to obscurely serrulate above; costa ½ to _ the leaf length in lateral leaves, shorter in dorsal leaves; cells broadly rhombic, rhomboidal or linear, lax or firm, thin-walled, alar cells undifferentiated. Dioicous. Perigonia terminal, bud-like. Setae reddish orange, smooth. Capsules cylindrical to pyriform, inclined to pendent; exothecial cells collenchymatous; stomata superficial; opercula conic-apiculate; annuli rudimentary or revoluble; peristome double, exostome densely ...
Ascending Colon. *Right ovary and Fallopian tube. *Right ureter. Clinical significance[edit]. If abdominal pain or signs of ... Examples of tumors in the left lower quadrant include colon cancer and ovarian tumor. ...
to ascending colon (distal loop) middle colic artery. to the transverse colon (distal loop) ... head of the pancreas and to the ascending and inferior parts of the duodenum (proximal loop) ... and supplies the intestine from the lower part of the duodenum through two-thirds of the transverse colon, as well as the ... and ileocecal branches anastomose with each other to form a marginal artery along the inner border of the colon. This artery is ...
... ascending colon, and the proximal 2/3 of the transverse colon. The final branch which is important for the digestive system is ... which includes the distal 1/3 of the transverse colon, descending colon, sigmoid colon, rectum, and the anus above the ... Parasympathetic innervation to the ascending colon is supplied by the vagus nerve. Sympathetic innervation is supplied by the ... and connects to the ascending colon of the large intestine. At this junction there is a sphincter or valve, the ileocecal valve ...
In an isolated intestinal transplant, the colon will be detached from the small intestine. The cecum and ascending colon are ... In a multivisceral graft, the stomach, duodenum, pancreas, and/or colon may be included in the graft. Multivisceral grafts are ... with concentrations of up to 104-107 CFU/mL in the jejunoileum and 1011-1012 CFU/mL in the colon. While suppression of the ...
Ascending colon (ascending in the back wall of the abdomen). *Right colic flexure (flexed portion of the ascending and ... lower duodenum, jejunum, ileum, cecum, appendix, ascending colon, and first two-third of the transverse colon. branches of the ... These include the esophagus, pylorus of the stomach, distal duodenum, ascending colon, descending colon and anal canal. In ... last third of the transverse colon, to the upper part of the anal canal. last third of the transverse colon, descending colon, ...
It is also separated from the colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon ... to the sigmoid colon, through the descending, transverse, and ascending sections. The cecum is an end point for the colon with ... It receives chyme from the ileum, and connects to the ascending colon of the large intestine. It is separated from the ileum by ... The connection between the end of the cecum and the beginning of the ascending colon is called the cecocolic orifice. ...
Inclusion of a diagram of the colon, labeling e.g. 'sigmoid colon', 'ascending colon', 'descending colon','transverse colon' ... The squatting theory is looking better and better, now that Burkitt's hunch about fiber has failed in the case of colon cancer ...
From colon 1 the ascending and transverse colon will be formed and from colon 2 the descending and sigmoid colons and the ... In tetrapods, the ileocaecal valve is always present, opening into the colon. The length of the small intestine is typically ...
... mutations are more commonly observed in cecal cancers than colorectal cancers located in any other places from ascending colon ... "Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma". Proceedings of the National Academy of ...
... any bleeding within the upper gastrointestinal tract or the ascending colon can lead to melena.[6] Melena may also be a ... Bleeds that originate from the lower gastrointestinal tract (such as the sigmoid colon and rectum) are generally associated ...
The endoscope is then passed through the anus up the rectum, the colon (sigmoid, descending, transverse and ascending colon, ... The colon is not a sterile environment; many bacteria that normally live in the colon ensure the well-functioning of the bowel ... The colon has distension sensors that can tell when there is unexpected gas pushing the colon walls out-thus the "second brain ... Colonoscopy reduces cancer rates by detecting some colon polyps and cancers on the left side of the colon early enough that ...
... ascending colon (left dorsal and ventral, pelvic flexure), the small intestine if distended (it is not normally palpable on ... Large colon impactions typically occur at the pelvic flexure and right dorsal colon, two areas where the lumen of the intestine ... The surgeon works to correct the volvulus and then removes any damaged colon. 95% of the colon may be resected, but often the ... usually in the right dorsal and transverse colon, but rarely in the small colon. They may also cause mucosal irritation or pain ...
Transverse colon[change , change source]. This part of the colon goes across the from the ascending colon. It goes underneath ... Ascending colon[change , change source]. This part of the colon goes from the cecum (where the small intestine ends) up the ... The colon is a part of the large intestine. It is between cecum and the rectum. The colon takes water from the feces that goes ... Sigmoid colon[change , change source]. This is the small "S" shaped part of the colon, about 40 cm in length, which goes from ...
2004). "Ascending colon cancer with hepatic metastasis and cholecystolithiasis in a patient with situs inversus totalis without ... 2004). "Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability ... promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations ... involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon ...
The left colic vein drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its ... Ascending branch Descending branch Ronald W. Dudek; Thomas M. Louis (11 February 2014). High-YieldTM Gross Anatomy. Lippincott ...
The tumors are usually in the ascending colon. They also have a good prognostic outcome, so if a patient were diagnosed with ...
Ascending colon), குறுக்குப் பெருங்குடலின் மூன்றில் இரு பகுதி பின்குடல். குறுக்குக் குடலின் இறுதி மூன்றில் ஒரு பகுதி, இறங்கு ...
... but partly lying behind the cecum at its junction with the ascending colon; (d) a single gland, between the layers of the ... along the medial side of the ascending colon. The mesocolic lymph nodes are numerous, and lie between the layers of the ... and the ascending and transverse parts of the colon; lymph drains into the preaortic glands. The lymphatics of cecum and ... mostly placed in the angle between the ileum and the colon, ... in close relation to the transverse colon; they are best ...
... the ascending colon, the transverse colon, the descending colon, the sigmoid colon, and the rectum. Sections of the colon are: ... Of the colon, the ascending colon, descending colon and rectum are retroperitoneal, while the cecum, appendix, transverse colon ... In ruminants, the ascending colon is known as the spiral colon. Taking into account all ages and sexes, colon cancer occurs ... The ascending colon receives fecal material as a liquid. The muscles of the colon then move the watery waste material forward ...
Shim HJ, Hong YK, Kim SJ, Choi YJ, Kang JG (2010). "Carcinosarcoma on ascending colon found by bowel perforation: a case report ... colon, uterus and ovaries. Four main hypotheses have been proposed for the cellular origins of carcinosarcoma, based largely on ...
Other locations include the ascending, transverse, and descending sections of the colon. Pouches and the stick-on appliances to ... Some common reasons are: A part of the colon has been removed, e.g. due to colon cancer requiring a total mesorectal excision, ... People with colostomies who have ostomies of the sigmoid colon or descending colon may have the option of irrigation, which ... A part of the colon has been operated upon and needs to be 'rested' until it is healed. In this case, the colostomy is often ...
... ascending colon, and the proximal 2/3 of the transverse colon. The final branch which is important for the digestive system is ... which includes the distal 1/3 of the transverse colon, descending colon, sigmoid colon, rectum, and the anus above the ... The cecum receives chyme from the last part of the small intestine, the ileum, and connects to the ascending colon of the large ... Parasympathetic innervation to the ascending colon is supplied by the vagus nerve. Sympathetic innervation is supplied by the ...
... the descending colon, sigmoid colon and rectum. In zoology, the term hindgut refers also to the cecum and ascending colon. ... In mammals, it includes the distal third of the transverse colon and the splenic flexure, ...
This space is defined by: The ascending colon and caecum laterally (further right). The transverse colon superiorly. The root ... The descending colon laterally (further left). Peritoneal recesses Paracolic gutters Anatomy photo:37:14-0200 at the SUNY ... Paracolic gutters are recesses between the abdominal wall and the colon. These gutters are clinically important because they ... in the abdominal cavity between the colon and the root of the mesentery. There are two paramesenteric gutters; the left ...
The lateral boundary of the retroperitoneum is defined by the ascending and descending colon. The retroperitoneum can be ...
The mesentery associated with the ascending colon and descending colon is resorbed, bringing these parts of the colon into ... the ascending colon and the initial two-thirds of the transverse colon. As the foetus grows larger, the mid-gut loop is drawn ... "the mesentery of the ascending colon fuses with the parietal peritoneum on this wall and disappears; consequently the ascending ... This process brings the ascending colon to lie vertically in the lateral right portion of the abdominal cavity apposed to the ...
... such as through the portal vein or transmigration from the colon, are considered less likely.[1] ... Ascending cholangitis, also known as acute cholangitis or simply cholangitis, is inflammation of the bile duct (cholangitis), ... Kinney TP (April 2007). "Management of ascending cholangitis". Gastrointest Endosc Clin N Am. 17 (2): 289-306. doi:10.1016/j. ... In ascending cholangitis, it is assumed that organisms migrate backwards up the bile duct as a result of partial obstruction ...
However, any bleeding within the upper gastrointestinal tract or the ascending colon can lead to melena. Melena may also be a ... such as the sigmoid colon and rectum) are generally associated with the passage of bright red blood, or hematochezia, ...
At the colon it divides into a descending branch, which anastomoses with the ileocolic, and an ascending branch, which ... These branches form arches, from the convexity of which vessels are distributed to the ascending colon. This article ... toward the middle of the ascending colon; sometimes the vessel lies at a higher level, and crosses the descending part of the ...
Ileum, cecum and ascending colon Cecum and ileum Ileo-cecal valve Ileo-cecal valve Pollard, MF; Thompson-Fawcett, MW; Stringer ... Approximately two liters of fluid enters the colon daily through the ileocecal valve. The histology of the ileocecal valve ...
Talk:Ascending cervical artery. *Talk:Ascending colon. *Talk:Ascending limb of loop of Henle ... Talk:Ascending branch of medial circumflex femoral artery. * ... Talk:Ascending palatine artery. *Talk:Ascending pharyngeal ...
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
... passes intact into the colon[citation needed]. Bacteria in the colon can metabolise lactose, and the resulting fermentation ... and it reaches the colon. The bacteria in the colon, mixed with the lactose, cause acidity in stools. Stools passed after the ... The unabsorbed sugars and fermentation products also raise the osmotic pressure of the colon, causing an increased flow of ...
appendix/colon). குடல்வாலழற்சி · பெருங்குடல் அழற்சி (போலிப்படலப் பெருங்குடல் அழற்சி, Ulcerative, Ischemic, Microscopic, ... Cholangitis (PSC, Secondary sclerosing cholangitis, Ascending) · Cholestasis/Mirizzi's syndrome · Biliary fistula · Haemobilia ...
Prevention includes the use of breast milk and probiotics.[2] A 2012 policy by the American Academy of Pediatrics recommended feeding preterm infants human milk, finding "significant short- and long-term beneficial effects," including reducing the rate of NEC by a factor of two or more.[10] Small amounts of oral feeds of human milk starting as soon as possible, while the infant is being primarily fed intravenously, primes the immature gut to mature and become ready to receive greater intake by mouth.[11] Human milk from a milk bank or donor can be used if mother's milk is unavailable. The gut mucosal cells do not get enough nourishment from arterial blood supply to stay healthy, especially in very premature infants, where the blood supply is limited due to immature development of the capillaries, so nutrients from the lumen of the gut are needed. A Cochrane review in 2014 found that supplementation of probiotics enterally "prevents severe NEC as well as all-cause mortality in preterm ...
ascending colon. *hepatic flexure. *transverse colon. *splenic flexure. *descending colon. *sigmoid colon ...
A Spigelian hernia (or lateral ventral hernia) is a hernia through the Spigelian fascia, which is the aponeurotic layer between the rectus abdominis muscle medially, and the semilunar line laterally. These are generally interparietal hernias, meaning that they do not lie below the subcutaneous fat but penetrate between the muscles of the abdominal wall; therefore, there is often no notable swelling. Spigelian hernias are usually small and therefore risk of strangulation is high. Most occur on the right side. (4th-7th decade of life.) Compared to other types of hernias they are rare.[1] ...
... causes hemorrhagic colitis and hemolytic-uremic syndrome by damaging endothelial cells in the microvasculature of the colon and ...
Volvulus of the ascending colon. A report of twenty-two cases. Am J Surg. 1967 Aug;114(2):323-332. ... Volvulus of the cecum and ascending colon. Am J Surg. 1973 Jun;125(6):672-675. ... en) Wertkin MG, Aufses AH., Jr Management of volvulus of the colon. Dis Colon Rectum. 1978 Jan-Feb;21(1):40-45. ... Volvulus of the sigmoid colon in Brazil: a report of 230 cases » Dis Colon Rectum. 1976 May-Jun;19(4):314-20. ...
In Haiti after the fall of Boyer, black leaders had ascended to the power once enjoyed exclusively by the mulatto elite.[76] ... activities and personal achievements earned him the Juan Pablo Duarte Order of Merit and the Order of Cristóbal Colón.[216] De ...
Thin ascending. *Thick ascending. *Distal convoluted tubule. *Collecting duct system *Connecting tubule ...
These arteries join (anastamoses) with ascending branches of the bronchial arteries, which are direct branches from the aorta, ...
Ipecac or ipecacuanha consists of the dried rhizome and roots of Cephaelis ipecacuanha. The medical virtues of ipecac are almost entirely due to the action of its alkaloids-emetine and cephaline. Till today, emetine remains one of the best drugs for treating amoebic liver abscess. It has a direct action on the trophozoites. Its greater concentration and duration of action in the liver as compared to that in the intestinal wall explains its high efficacy in amoebic liver abscess and also its low parasitic cure rate for intestinal amoebiasis. The drug is detoxicated and eliminated slowly. It may, therefore, produce cumulative effects. In man, emetine poisoning is characterized by muscular tremors, weakness and pain in the extremities which tend to persist until drug administration is stopped. Gastro-intestinal symptoms include nausea, vomiting and bloody diarrhoea. The latter may be mistaken for a recurrence of amoebic dysentery. Many clinicians fear the occurrence of cardiac toxicity due to this ...
Colon. *Ascending colon. *Hepatic flexure. *Transverse colon. *Splenic flexure. *Descending colon. *Sigmoid colon ...
The urine collected by the kidney is emptied into the cloaca through the ureters and then to the colon by reverse peristalsis. ... Both hearts are labeled with the following parts: 1. Ascending Aorta 2. Left Atrium 3. Left Ventricle 4. Right Ventricle 5. ...
... ascending colon, transverse colon ၏ ရှေ့ ၃ ပုံ ၂ ပုံ ပါဝင်သည်။ ... Hindgut တွင် အူမကြီး၏ Transverse colon နောက်ပိုင်း ၃ ပုံ ၁ ပုံ၊ descending colon, sigmoid colon, rectum, anus (စအို) တို့ ပါဝင် ...
വെർമിഫോം അപ്പന്റിക്സ്/Colon). *അപ്പെൻഡിസൈറ്റിസ്. *ആന്ത്രശൂല *Pseudomembranous. *Ulcerative. *Ischemic. *Microscopic. * ...
... such as colon, spleen, pancreas and small intestine to enter the hernia sac. ...
... appendix and ascending colon,[19] where they attach themselves to the mucosa[21] and ingest colonic contents.[24] ... and migrate through the small intestine towards the colon.[19] During this migration, they moult twice and become adults.[19][ ... The gravid female pinworms migrate through the colon towards the rectum at a rate of 12 to 14 cm per hour.[19] They emerge from ...
Adhesions form as a natural part of the body's healing process after surgery in a similar way that a scar forms. The term "adhesion" is applied when the scar extends from within one tissue across to another, usually across a virtual space such as the peritoneal cavity. Adhesion formation post-surgery typically occurs when two injured surfaces are close to one another. This often causes inflammation and causes fibrin deposits onto the damaged tissues.[2] The fibrin then connects the two adjacent structures where damage of the tissues occurred. The fibrin acts like a glue to seal the injury and builds the fledgling adhesion, said at this point to be "fibrinous." In body cavities such as the peritoneal, pericardial, and synovial cavities, a family of fibrinolytic enzymes may act to limit the extent of the initial fibrinous adhesion, and may even dissolve it. In many cases, the production or activity of these enzymes are compromised because of injury, however, and the fibrinous adhesion persists. If ...
In some cases FAP can manifest higher in the colon than usual (for example, the ascending colon,[citation needed] or proximal ... Colon resection surgery is recommended if numerous colon polyps are found due to high risk of early death from colon cancer. ... Without colectomy, colon cancer is virtually inevitable. The mean age of colon cancer in untreated individuals is 39 years ( ... There are several surgical options that involve the removal of either the colon or both the colon and rectum. ...
... (TD) is a stomach and intestinal infection. TD is defined as the passage of unformed stool (one or more by some definitions, three or more by others) while traveling.[2][3] It may be accompanied by abdominal cramps, nausea, fever, and bloating.[3] Occasionally bloody diarrhea may occur.[5] Most travelers recover within four days with little or no treatment.[3] About 10% of people may have symptoms for a week.[3] Bacteria are responsible for more than half of cases.[3] The bacteria enterotoxigenic Escherichia coli (ETEC) are typically the most common except in Southeast Asia, where Campylobacter is more prominent.[2][3] About 10% to 20% of cases are due to norovirus.[3] Protozoa such as Giardia may cause longer term disease.[3] The risk is greatest in the first two weeks of travel and among young adults.[2] People affected are more often from the developed world.[2] Recommendations for prevention include eating only properly cleaned and cooked food, drinking bottled water, and ...
appendix/colon). குடல்வாலழற்சி · பெருங்குடல் அழற்சி (போலிப்படலப் பெருங்குடல் அழற்சி, Ulcerative, Ischemic, Microscopic, ... Cholangitis (PSC, Secondary sclerosing cholangitis, Ascending) · Cholestasis/Mirizzi's syndrome · Biliary fistula · Haemobilia ...
Colon. ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon. continuous (taenia ...
An esophageal motility disorder (EMD) is any medical disorder causing difficulty in swallowing, regurgitation of food and a spasm-type pain which can be brought on by an allergic reaction to certain foods. The most prominent one is dysphagia. It is a part of CREST syndrome, referring to the five main features: calcinosis, Raynaud syndrome, esophageal dysmotility, sclerodactyly and telangiectasia.[1] ...
He ascended the top turnbuckle in an attempt to dive on his opponent, who countered with a dropkick. The challenger ascended ... The Colóns, and Rhodes and DiBiase (collectively known as The Legacy).[19] Two weeks following the event on the July 6 episode ... Hardy escaped with some offense before ascending the top turnbuckle and attempting with his finishing maneuver, the Swanton ...
A negative Murphy's sign does not rule out all gallbladder diseases as ascending cholangitis. Using an ultrasound transducer ...
... the ascending colon is the part of the colon located between the cecum and the transverse colon. The ascending colon is smaller ... with ascending colon (at left) measuring on average 6.6 cm (range 6.0-7.0 cm). 1: Ascending colon 2: Transverse colon 3: ... many casual mentions of the right colon chiefly concern the ascending colon. Parasympathetic innervation to the ascending colon ... The ascending colon is on the right side of the body (barring any malformations). The term right colon is hypernymous to ...
Several diseases can affect the ascending colon, or first part of your large intestine. If youre experiencing pain in this ... 4. Colon Cancer Colon cancer is the term people usually use to describe colorectal cancer, meaning cancer of the colon (which ... Diseases that affect the ascending colon include inflammatory bowel diseases and colon cancer. ... Crohns disease can affect any part of the digestive tract, often the ascending colon and the end of the small intestine. This ...
... ascending colon explanation free. What is ascending colon? Meaning of ascending colon medical term. What does ascending colon ... Looking for online definition of ascending colon in the Medical Dictionary? ... Related to ascending colon: descending colon. as·cend·ing co·lon. [TA] the portion of the colon between the ileocecal orifice ... ascending colon (7 cases), descending colon (5 cases), sigmoid colon (10 cases), rectum (14 cases), transverse colon (2 cases) ...
His ultrasonography (USG) examination showed a 9.5 cm long annular mass at the cecum and the ascending colon. An abdominal ... Solitary Plasmacytoma of the Cecum and the Ascending Colon: Surgical Resection as a Treatment Modality. ... mass localized at the medial border of the cecum in close proximity to the ileocecal valve extending into the ascending colon ( ... P-extramedullaries rarely occur in the GI tract, stomach, small bowel, colon, or rectum. SP usually presents in the 5th or 6th ...
... Tahsin Dalgic,1 Erdal ... J. G. Allison, E. P. Getaz, and W. G. Staples, "Primary isolated extramedullary plasmacytoma of the colon: a case report," ... W. Makis, A. Ciarallo, M. Hickeson, and R. Lisbona, "Gastric recurrence of a primary colon plasmacytoma: staging and evaluating ... "Primary isolated extramedullary plasmacytoma of colon," World Journal of Surgical Oncology, vol. 5, article 47, 2007. View at ...
... ascending colon explanation. Define ascending colon by Websters Dictionary, WordNet Lexical Database, Dictionary of Computing ... Ascending. ascending aorta. ascending artery. -- ascending colon --. Ascending latitude. Ascending line. ascending node. ... ascending colon Noun. 1.. ascending colon - the part of the large intestine that ascends from the cecum to the transverse colon ... Ascending series. Ascending signs. Ascension. Ascension Day. Ascension of Christ. Ascension of the Lord. Ascensional. ...
Ascending colon is part of the large intestine from where the feces pass. A burning sensation and pain may result due to an ... What does burning pain in ascending colon mean?. What does burning pain in ascending colon mean?. All questions. Answered ... Ascending colon is part of the large intestine from where the feces pass. A burning sensation and pain may result due to an ... Is there some descending pain in colon or is it just me thinking paranoid? ...
ICD-10-PCS code 0DBK3ZX for Excision of Ascending Colon, Percutaneous Approach, Diagnostic is a medical classification as ... Excision of Ascending Colon, Percutaneous Approach, Diagnostic 0DBK3ZX. ICD-10-PCS code 0DBK3ZX for Excision of Ascending Colon ... Ascending Colon. Definition: Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and ...
ICD-10-PCS code 0D1A4ZK for Bypass Jejunum to Ascending Colon, Percutaneous Endoscopic Approach is a medical classification as ... Bypass Jejunum to Ascending Colon, Percutaneous Endoscopic Approach 0D1A4ZK. ICD-10-PCS code 0D1A4ZK for Bypass Jejunum to ... Ascending Colon, Percutaneous Endoscopic Approach is a medical classification as listed by CMS under Gastrointestinal System ...
Fowler on ascending colon pain: "stomach pain" can be caused by lots of things & may indeed originate outside the GI tract. ... Ascending Colon (Definition) The ascending colon is the portion of the large intestine "ascending" or going up the right side ... Right colon: The ascending colon is the portion of the large intestine "ascending" or going up the right side of the abdomen. ... A ascending colon polyp worse then anywhere else in the colon.How can I prevent more. High grade removed in may, surgically. ...
Methods: Between January 2011 and September 2013, 20 consecutive patients with advanced ascending colon cancer near the hepatic ... Conclusions: This laparoscopic method is useful and feasible for ascending colon cancer near the hepatic flexure. ... We present a laparoscopic radical lymphadenectomy procedure for advanced ascending colon cancer near the hepatic flexure. ... Laparoscopic radical lymphadenectomy with complete mesocolic excision for advanced ascending colon cancer near the hepatic ...
2015/16 ICD-10-CM D3A.022 Benign carcinoid tumor of the ascending colon ... Short description: Ben carcinoid asc colon.. *ICD-9-CM 209.53 is a billable medical code that can be used to indicate a ... Benign carcinoid tumor of the ascending colon. * ... Benign carcinoid of ascending colon. *Benign carcinoid tumor ... Benign carcinoid tumor, ascending colon. *Benign neuroendocrine tumor of ascending colon. *Benign neuroendocrine tumor, ...
Short description: ASCENDING COLON INJ-CLOS.. *ICD-9-CM 863.41 is a billable medical code that can be used to indicate a ... Injury to ascending (right) colon without open wound into cavity. * ... 2015/16 ICD-10-CM S36.500A Unspecified injury of ascending [right] colon, initial encounter ... Ascending colon contusion. *Ascending colon laceration. *Blast injury of ascending colon. *Traumatic ascending colon ...
... By ... In and #64258;ammation of the terminal ileum secondary to an embedded plastic sword with ulceration in the ascending colon. ... A single 6-mm ulcer was found in the proximal ascending colon at the embedded site. ... a plastic sword pick with the tip and blade in the terminal ileum and the hilt embedded in the proximal ascending colon. The ...
Other injury of ascending [right] colon, initial encounter. 2016 2017 2018 2019 2020 Billable/Specific Code *S36.590A is a ... Other injury of colon. 2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code Applicable To*Secondary blast injury of colon ... Injury of colon. 2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code Type 2 Excludes*injury of rectum (S36.6-) ... effects of foreign body in stomach, small intestine and colon (T18.2-T18.4) ...
Aintree - Herniation of the Caecum and Ascending Colon Through the Foramen of Winslow: A Case Report and Review. Authors: ...
Malignant neoplasm of ascending colon. 2016 2017 2018 2019 2020 Billable/Specific Code *C18.2 is a billable/specific ICD-10-CM ... Primary malignant neoplasm of ascending colon. ICD-10-CM C18.2 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0): * ... Malignant neoplasm of colon. 2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code Type 1 Excludes*malignant carcinoid tumors ... Cancer of the colon, ascending. *Primary adenocarcinoma of ascending colon. * ...
... May 25, 2017 Anatomy The small intestine connects to the colon where a valve regulates ... As the colon moves towards the head, it is called the ascending colon. It then moves laterally across the abdomen where it is ... the descending colon. The colon is responsible for resabsorption of water and collect undigested waste for elimination. The ... The cecum is a pouch-like section of the large intestine that is the first part of the colon, also called the large intestine. ...
The colon is a 5-6-ft long, U-shaped part of the large intestine (lower gastrointestinal tract). By definition, the cecum (and ... appendix) and ano-rectum, which are parts of the large intestine, are not included in the colon. ... ascending colon, transverse colon, descending colon, and sigmoid colon; they are not present in the rectum. In the ascending ... ascending colon to proximal transverse colon) and partly from the hind gut (distal transverse colon to sigmoid colon). ...
Colon cancer (colorectal cancer) support forum. Please feel free to read, share your thoughts, your stories and connect with ... Hi has anybody been able to feel their ascending colon? Im slim and doctors say its my colon I can feel but it feels swollen ... Hi has anybody been able to feel their ascending colon? Previously I was able to feel it.. Right now I do not feel it anymore. ... Swollen ascending colon. Please feel free to read, share your thoughts, your stories and connect with others!. ...
Microvascular permeability changes in ischemia/reperfusion injury in the ascending colon of horses. Journal of the American ... Microvascular permeability changes in ischemia/reperfusion injury in the ascending colon of horses. / Henninger, D. D.; Snyder ... We concluded that ischemia of the ascending colon, when followed by reperfusion, results in a significant increase in ... We concluded that ischemia of the ascending colon, when followed by reperfusion, results in a significant increase in ...
Oncolex - cancer encyclopedia › About cancer in the colon/rectum › Treatment › Surgery colon › Tumor in cecum and ascending ... Surgery colonTumor in cecum and ascending Tumor in right flexure Tumor in transversumTumor in left flexure Tumor in descending ... Tumor in the cecum and ascending colon. GeneralEquipmentPreparationImplementationFollow-up ... Tumor in sigmoideumLocally advanced colon. Surgery rectumTEMLow anterior resectionRectum amputation (APE)Rectum amputation with ...
drugsupdate.com - Indias leading online platform for Doctors and health care professionals. Updates on Drugs, news, journals, 1000s of videos, national and international events, product-launches and much more...Latest drugs in India, drugs, drugs update, drugs update
Oncolex - cancer encyclopedia › Treatment › Surgery › Tumor in cecum and ascending. Tumor in the cecum and ascending colon. ... For cancer in the cecum and ascending colon a right-sided hemicolectomy and a standard resection of colon- and lymph nodes are ... Dissect in the anatomical plane dorsal to the mesocolon of the transversal and ascending colon and coecum. This is anterior to ... Step2 - Release the transverse colon from the middle to the right flexure.. *The gastrocolic ligament (the greater omentum) is ...
The anus and other parts of the colon show feminine tensions, while the ascending colon exposes more masculine tensions. ... Bowel - large bowel - ascending colon. Published on Digestive system.. This is where fermentation takes place. The person who ... The person with problems in the ascending colon may be an individual with problems in his relationship with his Father or male ... Tensions associated with the ascending colon are clearly masculine, yang, and connected with the biological Father, the male ...
Director: Colon Assany , Stars: Eric Assani, Colon Assany, Giresse Kassonga, Francine Muika ... The Democratic Republic Of Congo (Sorted by Popularity Ascending) View Mode: Compact , Detailed ...
Download this Colon Organ Anatomy photo now. And search more of the webs best library of royalty-free stock images from iStock ... Colon organ anatomy - Stock image. .... Abdomen, Anatomy, Ascending Colon, Biomedical Illustration, Blue. ...
The ICD-10 Code C18.2 is the code used for Malignant neoplasm of ascending colon .An alternative description for this code is ...
  • Inner diameters of different sections of the large intestine, with ascending colon (at left) measuring on average 6.6 cm (range 6.0-7.0 cm). 1: Ascending colon 2: Transverse colon 3: Descending colon 4: Sigmoid colon 5: Rectum Intestines Front view of the thoracic and abdominal viscera. (wikipedia.org)
  • Successful endoscopic mucosal resection of a solitary extramedullary plasmacytoma in the sigmoid colon," Endoscopy , vol. 43, no. 2, pp. (hindawi.com)
  • Embryologically, the colon develops partly from the midgut (ascending colon to proximal transverse colon) and partly from the hind gut (distal transverse colon to sigmoid colon). (medscape.com)
  • the sigmoid colon is so called because of its S-shape. (medscape.com)
  • The transverse colon and the sigmoid colon have a mesentery (ie, transverse mesocolon and sigmoid mesocolon, respectively), but the ascending colon and descending colon are retroperitoneal, while the cecum is intraperitoneal but uses the mesentery of the ileum. (medscape.com)
  • The colon is supplied by the superior mesenteric artery through its right colic and middle colic branches and by the inferior mesenteric artery through its left colic and multiple sigmoid branches. (medscape.com)
  • The colon is divided into four main sections--ascending or right colon, transverse colon, descending or left colon, and the sigmoid colon. (livestrong.com)
  • The sigmoid colon is considered a part of the left colon. (livestrong.com)
  • The colonic contents travel from the small intestine up the ascending colon then along the transverse colon then down the descending colon and sigmoid before entering the rectum. (livestrong.com)
  • Though these symptoms may also be seen in cancers in the right colon, they are most often seen in the left because the stool is more solid in the descending and sigmoid colon. (livestrong.com)
  • The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. (colonoscopyandendoscopybilling.com)
  • The sigmoid colon is the part of the large intestine after the descending colon and before the rectum. (colonoscopyandendoscopybilling.com)
  • The walls of the sigmoid colon are muscular, and contract to increase the pressure inside the colon, causing the stool to move into the rectum. (colonoscopyandendoscopybilling.com)
  • The sigmoid colon is supplied with blood from several branches (usually between 2 and 6) of the sigmoid arteries, a branch of the IMA. (colonoscopyandendoscopybilling.com)
  • Its four parts are the ascending colon , transverse colon , descending colon and sigmoid colon . (cancerqld.org.au)
  • The rectum extends through the pelvis from the end of the sigmoid colon to the anus. (limamemorial.org)
  • I was sent for a colonoscopy, and a mass was discovered which was determined to be stage 3B cancer of the sigmoid colon. (medicinenet.com)
  • The food travels across the abdomen in the transverse colon, goes back down the other side of the body in the descending colon, and then through the sigmoid colon. (answers.com)
  • The sigmoid colon is the last part of the colon and connects to the rectum. (cancer.ca)
  • The distal colon is the descending colon and the sigmoid colon together. (cancer.ca)
  • The rectum is the lower part of the large intestine that connects to the sigmoid colon. (cancer.ca)
  • The rectum measures six to 12 inches long and is located between the sigmoid colon and the anus . (verywellhealth.com)
  • Diseases that affect the ascending colon include inflammatory bowel diseases and colon cancer. (livestrong.com)
  • Whenever there is evidence of dysplasia or cancer in the setting of crohn's colitis , it is probably better to consider a total proctocolectomy as there is high risk of synchronous cancer or recurrence elsewhere in the colon . (healthtap.com)
  • Complete mesocolic excision has translated into lower local recurrence rates and better overall survival in colon cancer patients. (sages.org)
  • For cancer of the hepatic flexure of the colon, roughly 5% of lymph nodes over the head of the pancreas are positive. (sages.org)
  • We present a laparoscopic radical lymphadenectomy procedure for advanced ascending colon cancer near the hepatic flexure. (sages.org)
  • Between January 2011 and September 2013, 20 consecutive patients with advanced ascending colon cancer near the hepatic flexure underwent curative laparoscopic right hemicolectomy. (sages.org)
  • This laparoscopic method is useful and feasible for ascending colon cancer near the hepatic flexure. (sages.org)
  • For cancer in the cecum and ascending colon a right-sided hemicolectomy and a standard resection of colon- and lymph nodes are performed. (oncolex.org)
  • Cancer of the colon, like all cancers, is associated with a great tension that the person experienced and did not verbalize, kept well hidden. (flowsandforms.com)
  • Colon cancer is a potentially curable disease if it is caught in the early stages. (livestrong.com)
  • The symptoms of colon cancer vary according to location of the cancer within the colon as well as any spread outside the colon. (livestrong.com)
  • The symptoms of left-sided colon cancer are attributed the anatomy of that area of the colon. (livestrong.com)
  • This occurs when the lumen of the colon has been completely obstructed by cancer. (livestrong.com)
  • Cancer in the transverse colon has a mixture of the symptoms experienced in right and left colon due to the semi-solid nature of stool in this segment. (livestrong.com)
  • [1] It is possible to have medical problems with the descending colon including ulcers , cancer and Crohn's disease . (wikipedia.org)
  • Cutaneous metastasis of ascending colon cancer harboring a BRAF V600E mutation: A rare case report. (bvsalud.org)
  • PATIENT CONCERNS We treated a 62-year-old woman with multiple cutaneous metastatic nodules on the chest , back , and armpit 7 months after resection of ascending colon cancer . (bvsalud.org)
  • DIAGNOSES The patient was diagnosed with cutaneous metastasis of ascending colon cancer with BRAF V600E mutation . (bvsalud.org)
  • We present the first instance of a completely laparoscopically assisted resection and hernia repair on a patient with T4 ascending colon cancer. (springeropen.com)
  • a Axial view demonstrating right-sided inguinoscrotal hernia (black arrows) containing large bowel with thickening of the wall representing the ascending colon cancer (white arrows) and herniated terminal ileum (dashed white arrow). (springeropen.com)
  • An operation for rectal cancer, which involves removing part of the colon and the rectum and anus and creating a permanent colostomy. (cancerqld.org.au)
  • Examples of tumors in the left lower quadrant include colon cancer and ovarian tumor . (wikipedia.org)
  • I was Stage IIIB Colon Cancer and had surgery on Jan. 7th 2009 plus 6 months of FOLFOX. (cancer.org)
  • Lymph node metastasis to the iliac or inguinal region of colon cancer is extremely rare. (springeropen.com)
  • We experienced a case of ascending colon cancer with synchronous isolated right external iliac and inguinal lymph node metastases but without any regional lymph node metastasis. (springeropen.com)
  • Colonoscopy and computed tomography revealed an ascending colon cancer and also right external iliac and inguinal lymph node swelling. (springeropen.com)
  • Histological examination revealed that both lymph nodes were metastasized from colon cancer, and there was no evidence of regional lymph node metastasis. (springeropen.com)
  • In this report, we describe an extremely rare case of ascending colon cancer with synchronous isolated right external iliac and inguinal lymph node metastases with neither regional lymph node metastasis nor distant hematogenous metastasis, for whom a potentially curative operation which included distant metastatic lymph node dissection was performed. (springeropen.com)
  • Colonoscopy revealed an ascending colon tumor (Fig. 1 ), which was histologically proven to be a colon cancer (well-differentiated adenocarcinoma). (springeropen.com)
  • Computed tomography (CT) demonstrated not only the ascending colon cancer but also the enlarged right external iliac and inguinal lymph nodes, whereas neither the apparent metastasis to the principle organs nor regional lymph nodes were detected. (springeropen.com)
  • As for the external iliac and inguinal lymph nodes, both of them were well-differentiated adenocarcinoma and revealed to be metastasis from the colon cancer by immunohistochemical examination, which revealed a profile that cytokeratin 7 was negative and cytokeratin 20 and caudal-related homeobox 2 (CDX2) were positive (Fig. 4 ) [ 8 ]. (springeropen.com)
  • Which large intestine disorder is associated with a higher risk of colon cancer? (studystack.com)
  • Colon cancer is the most common, and the most preventable, form of gastrointestinal cancer and the third most common cancer in the United States. (medscape.com)
  • A subset of colon cancers (2-5%) are associated with inherited syndromes, including Lynch syndrome, familial adenomatous polyposis, MUTYH-associated polyposis, and certain hamartomatous polyposis conditions, each condition associated with a far higher risk of developing colon cancer. (medscape.com)
  • Diseases associated with SPDEF include Allergic Cutaneous Vasculitis and Ascending Colon Cancer . (genecards.org)
  • Colon cancer occurs with the presence of cancer cells in the colon or large intestine of the digestive system. (loyolamedicine.org)
  • The term "colon cancer" is often blended with the term "rectal cancer" to form the hybrid term colorectal cancer. (loyolamedicine.org)
  • Cancer cells within the colon or rectum are called adenocarcinoma. (loyolamedicine.org)
  • colon cancer begins specifically in the colon while rectal cancer begins in the rectum. (loyolamedicine.org)
  • Signs and symptoms of colon cancer are very similar to symptoms of inflammatory bowel disease and other gastrointestinal illnesses. (loyolamedicine.org)
  • It is important to monitor your digestive health and consult with your doctor if you experience a combination of any signs or symptoms of colon cancer. (loyolamedicine.org)
  • For instance, obese males over the age of 50 are at a higher risk of developing colon cancer. (loyolamedicine.org)
  • Lifestyle factors such as smoking, exercise, and nutrition also influence an individual's risk of developing colon cancer. (loyolamedicine.org)
  • Bowel inflammation, which often occurs in inflammatory bowel disease , also increases the risk of developing colon cancer. (loyolamedicine.org)
  • Colonoscopy , or an examination of the entire rectum and colon using a scoping tool, is the most common method used to identify the presence of cancer cells or tumors in the colon. (loyolamedicine.org)
  • Other imaging techniques used to test or diagnose colon cancer include specialized stool tests, magnetic resonance imaging (MRI) , computed tomography (CT or CAT) scans , tiny cameras implanted in swallowable pills (capsule endoscopy), and positron emission tomography (PET) or PET-CT scans. (loyolamedicine.org)
  • Colon cancer surgery at Loyola University Medical Center is rated as a high-performing speciality by U.S. News & World Report's on the 2020-21 Best Hospitals list. (loyolamedicine.org)
  • How was the diagnosis of your colon cancer established? (medicinenet.com)
  • My colon cancer diagnosis was established by colonoscopy biopsy followed by lower gastro intestinal CT with contrast, and confirmed by urgent surgery. (medicinenet.com)
  • It took the doctors and the hospital 3 months to figure out I didn't have gastritis , but stage 4 small colon cancer . (medicinenet.com)
  • My wife was diagnosed with stage one colon cancer the doctors said he got all the cancer out after removing about twelve inches of her colon. (medicinenet.com)
  • After surgery and lab test her colon cancer spread to her cervix. (medicinenet.com)
  • I never would've thought polyps or colon cancer, no family members had it. (medicinenet.com)
  • I had polyp in lower colon, had a little bit of cancer in the polyp (not in base). (medicinenet.com)
  • I was at stage 3B colon cancer. (medicinenet.com)
  • I was diagnosed with stage IV colon cancer, which had spread to the lymph nodes , in 2005. (medicinenet.com)
  • This activity outlines the etiology, epidemiology, clinical staging and stage-wise treatment of colon cancer. (nih.gov)
  • Describe the pathophysiology of colon cancer. (nih.gov)
  • Outline the clinical presentation of colon cancer. (nih.gov)
  • Discuss the role of early involvement of an interprofessional team including clinicians, nutritionists and dieticians, palliative service, social workers and case managers in helping improve the quality of life for patients diagnosed with colon cancer. (nih.gov)
  • The most important prognostic colon cancer indicator is the pathological stage at presentation. (nih.gov)
  • Baseline computed tomography (CT) of the chest, abdomen, and pelvis with contrast and carcinoembryonic antigen (CEA) are the preferred cost-effective, colon-cancer staging studies done before surgical resection. (nih.gov)
  • Surgical resection is the main treatment modality for localized early-stage colon cancer. (nih.gov)
  • Adjuvant therapy could augment the chance of cure on high-risk patients with colon cancer. (nih.gov)
  • Oligo-metastatic, liver and lung, and local-recurrence patients with colon cancer are potential curable candidates with multimodality therapies. (nih.gov)
  • Palliative systemic therapy is reserved for non-surgical colon cancer candidates aiming to improve quality of life and prolong life expectancy. (nih.gov)
  • If cancer develops in the cecum, it is treated like colon cancer. (cancer.ca)
  • When part of the colon or rectum is removed to treat cancer, nearby mesentery is also removed. (cancer.ca)
  • What Is Colon Cancer? (verywellhealth.com)
  • Colon cancer begins when abnormal cells within the colon start growing uncontrollably. (verywellhealth.com)
  • There are several factors that increase a person's chance of developing colon cancer, some within a person's control (for example, being overweight and leading a sedentary lifestyle) and some not (for example, having an inflammatory bowel disease). (verywellhealth.com)
  • Colon cancer is the third most common cancer in the United States, with around 100,000 new cases being diagnosed each year, according to the National Cancer Institute . (verywellhealth.com)
  • The term colon cancer is sometimes used interchangeably with colorectal cancer because colon and rectal cancer share common features. (verywellhealth.com)
  • Adenocarcinoma is the most common type of colon cancer, accounting for approximately 96 percent of diagnoses. (verywellhealth.com)
  • This type of cancer originates in the mucus-secreting glands of the colon. (verywellhealth.com)
  • There are many potential symptoms of colon cancer , and what symptoms a person experiences depends on factors like the location and size of the cancer. (verywellhealth.com)
  • Keep in mind that some people experience no symptoms in the early stages of colon cancer. (verywellhealth.com)
  • What Are the Symptoms of Colon Cancer? (verywellhealth.com)
  • Most colon cancers are caused by growths within the inner lining of the colon, called polyps, that change into cancer over many years. (verywellhealth.com)
  • here it bends abruptly forward and to the left, forming the right colic flexure (hepatic) where it becomes the transverse colon. (wikipedia.org)
  • the segment of the colon that extends up the cecum in the lower right side of the colic fissure to the abdomen to the transverse colon at the hepatic flexure on the right side. (thefreedictionary.com)
  • The first segment of the colon, which begins in the right lower quadrant of the abdomen at the caecum and ends at the hepatic (right colic) flexure in the right upper quadrant of abdomen, after which point it becomes the transverse colon. (thefreedictionary.com)
  • The ascending colon takes a right-angled turn just below the liver (right colic or hepatic flexure) and becomes the transverse colon, which has a horizontal course from right to left, occupying the right hypochondrium, epigastrium, and left hypochondrium. (medscape.com)
  • It is the part of the colon from the cecum to the hepatic flexure (the turn of the colon by the liver). (colonoscopyandendoscopybilling.com)
  • It continues upward to a bend in the colon called the hepatic flexure. (cancer.ca)
  • The transverse colon follows the ascending colon and hepatic flexure. (cancer.ca)
  • In the caudal abdomen the colon curves to the midline and joins the rectum. (thefreedictionary.com)
  • In the ruminants and the pig this takes the form of a spiral colon of centrifugal and centripetal loops which occupies the right side of the abdomen. (thefreedictionary.com)
  • It then moves laterally across the abdomen where it is called the transverse colon and finally makes the turn to head toward the posterior of the body, the descending colon . (anatomycorner.com)
  • Colon anatomy, front of abdomen. (medscape.com)
  • Lateral to ascending and descending colon are the right and left paracolic gutters of the peritoneal cavity, through which fluid/pus in the upper abdomen can trickle down into the pelvic cavity. (medscape.com)
  • This part of the colon goes from the cecum (where the small intestine ends) up the right hand side of the abdomen . (wikipedia.org)
  • The ascending colon, on the right side of the abdomen, is about 25 cm long in humans. (colonoscopyandendoscopybilling.com)
  • The portion of colon that begins in the lower right part of the abdomen, departing from the end of the small intestine. (oreilly.com)
  • The colon and rectum are held in the abdomen by folds of tissue called mesenteries. (cancer.ca)
  • The mesocolon is a mesentery that attaches the colon to the wall of the abdomen. (cancer.ca)
  • The colon is located around the perimeter of the abdomen and is about five feet in length. (verywellhealth.com)
  • What Are the Treatments for Malignant Colon Polyps? (livestrong.com)
  • What are the most common polyps found in the colon? (brainscape.com)
  • Pendunculated polyps hang off ___ attached to the walls of the colon. (brainscape.com)
  • The colonoscopy revealed a constricting ulcerovegetative mass localized at the medial border of the cecum in close proximity to the ileocecal valve extending into the ascending colon (Figure 1 ). (hindawi.com)
  • Based on the history, a colonoscopy was performed, which revealed a plastic sword pick with the tip and blade in the terminal ileum and the hilt embedded in the proximal ascending colon. (appliedradiology.com)
  • Colonoscopy demonstrated a large non-obstructing tumour located at the ascending colon. (springeropen.com)
  • Colonoscopy showed a polyp of ascending colon. (slideshare.net)
  • In almost all patients, a diagnostic or screening colonoscopy is required for tissue biopsy pathological confirmation of colon carcinoma. (nih.gov)
  • This chronic inflammatory disorder can affect all layers of the colon, and there is often normal, healthy bowel tissue between patches of affected or diseased bowel, according to the Crohn's & Colitis Foundation of America (CCFA). (livestrong.com)
  • Lower left stomach pain in women from colon or bowel? (healthtap.com)
  • Position the omentum above the liver, Lift the transverse colon cranially and luxate the small bowel package over the midline to the left. (oncolex.org)
  • Dissect on to the bowel wall along the whole circumference where the transverse colon is to be transected. (oncolex.org)
  • The large bowel includes the colon and the rectum. (cancerqld.org.au)
  • Inflammatory bowel diseases (IBD), including Crohn's disease (CD), and ulcerative colitis (UC), are a group of inflammatory conditions related to the colon and small intestines and characterized by chronic inflammation. (frontiersin.org)
  • The large bowel is also called the large intestine or colon. (medlineplus.gov)
  • lymph nodes (3 cm-5 cm) mostly in the ileocecal region, Clinical Manifestations and Surgical Findings and substantial edema involving one segment of small bowel, cecum, or ascending colon. (cdc.gov)
  • Its four main sections are the caecum, colon , rectum and anus. (cancerqld.org.au)
  • One who specializes in diseases of the colon, rectum and anus. (studystack.com)
  • The large intestine is made up of the cecum, colon, rectum and anus. (cancer.ca)
  • Cancers in this part of the colon tend to go unnoticed for a long time. (livestrong.com)
  • In most cases of colon or rectal cancers, the cause or causes are unknown. (limamemorial.org)
  • Right sided cancers (appendic, caecum, ascending & transverse colon) contribute to a 3rd of colorectal maligancies. (sages.org)
  • Up to one third of colon cancers exhibit increased familial risk. (medscape.com)
  • Based on the tissues involved, colon cancers be further broken down into various types. (verywellhealth.com)
  • A single 6-mm ulcer was found in the proximal ascending colon at the embedded site. (appliedradiology.com)
  • A. Large flat polyp in proximal ascending colon. (mayoclinic.org)
  • The cecum is a pouch-like passage that connects the colon to the ileum (the last part of the small intestine). (cancer.ca)
  • Ulcerative colitis is a disease that can affect the ascending colon and is characterized by inflammation and sores, or ulcers, that line the inner wall of the large intestine, says the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health. (livestrong.com)
  • Although diverticula can form at any point in the digestive tract, the most common location for diverticula is the colon. (livestrong.com)
  • Crohn's disease can affect any part of the digestive tract, often the ascending colon and the end of the small intestine. (livestrong.com)
  • Your colon, also known as the large intestine, is part of your digestive system. (icdlist.com)
  • The function of the descending colon in the digestive system is to store food that will be emptied into the rectum. (colonoscopyandendoscopybilling.com)
  • It is the last part of the digestive tract and made up of the cecum, colon, and rectum. (healthline.com)
  • The colon is part of the large intestine, the final part of the digestive system. (healthline.com)
  • Also the tumors that develop in the ascending colon tend to grow along the wall of the colon instead of directly outward into the lumen. (livestrong.com)
  • In the anatomy of humans and homologous primates, the ascending colon is the part of the colon located between the cecum and the transverse colon. (wikipedia.org)
  • The colon anatomy is displayed in the image below. (medscape.com)
  • These symptoms are explained by the anatomy of ascending colon. (livestrong.com)
  • In human anatomy , the superior mesenteric artery (SMA) arises from the anterior surface of the abdominal aorta , just inferior to the origin of the celiac trunk , and supplies the intestine from the lower part of the duodenum through two-thirds of the transverse colon , as well as the pancreas . (wikipedia.org)
  • The transverse colon again takes a right-angled turn just below the spleen (left colic or splenic flexure, which is attached to the diaphragm by the phrenocolic ligament) and becomes the descending (left) colon, which lies vertically in the most lateral left part of the abdominal cavity, occupying the left hypochondrium, left lumbar region, and left iliac fossa. (medscape.com)
  • It ends with a bend in the colon called the splenic flexure. (cancer.ca)
  • The descending colon follows the transverse colon and splenic flexure. (cancer.ca)
  • There is an ascending colon which begins at the cecum, passes forward to the cranial part of the abdominal cavity then crosses to the left side as the transverse colon. (thefreedictionary.com)
  • On plain abdominal radiographs, the colon is seen to be filled with air and some fecal material. (medscape.com)
  • The ascending (right) colon lies vertically in the most lateral right part of the abdominal cavity, occupying the right iliac fossa, right lumbar region and right hypochondrium. (medscape.com)
  • The location of the parts of the colon are either in the abdominal cavity or behind it in the retroperitoneum. (colonoscopyandendoscopybilling.com)
  • On the posterior side, the transverse colon is connected to the posterior abdominal wall by a mesentery known as the transverse mesocolon. (colonoscopyandendoscopybilling.com)
  • It is not extensive in the horse, in which it has an unusually long mesentery and is known as the small colon. (thefreedictionary.com)
  • Surgical removal of the displaced colon from its entrapment across the top of the gastrosplenic ligament is the only effective treatment. (thefreedictionary.com)
  • Have you done surgical resection of ascending colon in Crohn's colitis? (healthtap.com)
  • A surgical specimen showed type 2 tumor (50 × 35 mm) in the ascending colon (Fig. 3 c) and the histopathological examination demonstrated the tumor to be a subserosa-invasive well-differentiated adenocarcinoma (Fig. 4 ). (springeropen.com)
  • 3. Surgical results confirmed polyp of the ascending colon which pathology result is tubular polyp. (slideshare.net)
  • When compared with surgical excision, EMR offers preservation of the colon, and decreased morbidity and cost. (mayoclinic.org)
  • By definition, the cecum (and appendix) and ano-rectum, which are parts of the large intestine , are not included in the colon. (medscape.com)
  • The appendicular vein removes oxygen-depleted blood from the appendix, which is located at the bottom of the ascending colon. (healthline.com)
  • They had to remove a foot and a half of my small colon (doing a resection), my appendix , one ovary, and part of the large colon. (medicinenet.com)
  • Months later, she reported that her appendix had ruptured, formed an abcess, and poisoned much of her ascending colon. (thermogramcenter.com)
  • He had two months to recover from colon surgery and then had a liver resection. (cancer.org)
  • It rises on the right side up to the rib cage, where it turns to cross under the liver as the transverse colon. (oreilly.com)
  • First portion of the colon, extending from the lower border of the liver. (studystack.com)
  • The anus and other parts of the colon show feminine tensions, while the ascending colon exposes more masculine tensions. (flowsandforms.com)
  • It receives waste from the colon and stores it until it passes out of the body through the anus. (cancer.ca)
  • Ascending colon is part of the large intestine from where the feces pass. (organicfacts.net)
  • Symptoms on the left side of the colon are usually caused by growth outward into the lumen, obstructing the flow of feces. (livestrong.com)
  • The colon takes water from the feces that goes through it. (wikipedia.org)
  • The middle image was taken months after the surgery to remove the abcess and approximately 9 inches of ascending colon. (thermogramcenter.com)
  • ICD-10-PCS code 0DBK3ZX for Excision of Ascending Colon, Percutaneous Approach, Diagnostic is a medical classification as listed by CMS under Gastrointestinal System range. (aapc.com)
  • Ascending colon Mesenteric relation of intestines. (wikipedia.org)
  • ICD-10-PCS code 0D1A4ZK for Bypass Jejunum to Ascending Colon, Percutaneous Endoscopic Approach is a medical classification as listed by CMS under Gastrointestinal System range. (aapc.com)
  • The colon is identified with haustra (irregular incomplete sacculations confer regular complete valvulae conniventes in jejunum). (medscape.com)
  • Lymphatic drainage from the entire colon and proximal two-thirds of the rectum is to the paraaortic lymph nodes that then drain into the cisterna chyli. (colonoscopyandendoscopybilling.com)
  • F-deoxyglucose positron emission tomography (FDG-PET) demonstrated a significant accumulation of 18F-fluorodeoxy glucose in the main colon tumor with the standardized uptake value (SUV) of 17.9 and external iliac and inguinal lymph nodes with SUV of 9.1 and 25.1, respectively, which suggested these were metastatic lymph nodes of an unknown origin (Fig. 2 ). (springeropen.com)
  • CT shows the enlarged right external iliac ( a ) and inguinal ( b ) lymph nodes, and FDG-PET shows a significant accumulation of FDG into the primary colon lesion with the SUV of 17.9 and external iliac and inguinal lymph nodes with SUV of 9.1 and 25.1, respectively ( c ). (springeropen.com)
  • A better handling of the colon, however, before acute or chronic lesion develop may become possible, especially if we are directed to the area as a definite region of slower progress. (naver.com)
  • Colonic endoscopic mucosal resection (EMR) consists of submucosal fluid injection to lift the polyp from the muscularis propria followed by snare resection of the lesion en bloc (in one piece) or in a piecemeal fashion. (mayoclinic.org)
  • An 83-year-old man presented for further investigation of his iron deficiency anaemia and was diagnosed with adenocarcinoma of the ascending colon. (springeropen.com)
  • The stool is still in liquid form in the ascending colon. (livestrong.com)
  • Forces the stool produced in colon to the rectum. (prezi.com)
  • The liquid waste remaining in the colon is formed into semi-solid stool. (cancer.ca)
  • The mucosa also makes mucus that helps stool move easily through the colon and rectum. (cancer.ca)
  • As stool moves through the colon, more water is absorbed from it and it becomes more solid. (cancer.ca)
  • Stool leaves the colon and moves into the rectum. (cancer.ca)
  • Inflammation and ulceration of the innermost lining of the colon. (studystack.com)
  • the ascending colon is also related to the C loop (second part) of the duodenum . (medscape.com)
  • A continuing series of anastomoses between the distal branch of the proximal artery and the proximal branch of the distal artery runs along the mesenteric (inner) border of the colon and is called the marginal artery of Drummond. (medscape.com)
  • The marginal artery allows a long length of colon to be mobilized (eg, to be taken up into the chest to replace the esophagus after esophagectomy). (medscape.com)
  • The arc of Riolan or the meandering mesenteric artery is a communication between the middle colic artery (or its left branch) and the left colic artery (or its ascending branch). (medscape.com)
  • Arterial supply to the colon comes from branches of the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). (colonoscopyandendoscopybilling.com)
  • Flow between these two systems communicates via a "marginal artery" that runs parallel to the colon for its entire length. (colonoscopyandendoscopybilling.com)
  • Arterial supply of the ascending colon comes from the ileocolic artery and right colic artery, both branches of the SMA. (colonoscopyandendoscopybilling.com)
  • The proximal two-thirds of the transverse colon is perfused by the middle colic artery, a branch of superior mesenteric artery, while the latter third is supplied by branches of the inferior mesenteric artery. (colonoscopyandendoscopybilling.com)
  • The middle, right, and ileocecal branches anastomose with each other to form a marginal artery along the inner border of the colon. (wikipedia.org)
  • arterial supply to the ascending colon is provided by the ielocolic and the ____ _____ artery. (sporcle.com)
  • The obstructed segment of the colon becomes markedly swollen and does not function as it should. (livestrong.com)
  • Second segment of the colon (middle section of the large intestine). (ikonet.com)
  • 1. CASE 326: INTUSSUSCEPTION of COLON INDUCED by POLYP,Dr LÊ TỰ PHÚC, MEDIC MEDICAL CENTER, HCMC, VIETNAM A 4 years-oldboypresentedtoMedicCenterwithone year history of weakness, fatigue, lethargy, pale skin and less active. (slideshare.net)
  • Sonologist suspected a intussusception of the ascending colon secondary to a polyp. (slideshare.net)
  • The cecum is a pouch-like section of the large intestine that is the first part of the colon, also called the large intestine. (anatomycorner.com)
  • The rectum is a part of the colon, and both organs together are called the large intestine. (verywellhealth.com)
  • The Mayo Clinic describes diverticulitis as an inflammation of one or more of a person's gut diverticula - small pouches of the inner lining of the colon that push through the colon's muscular outer wall. (livestrong.com)
  • In the horse there is the additional oddity of a significant reduction in diameter at the small colon, the terminal part which joins the rectum. (thefreedictionary.com)
  • The small intestine connects to the colon where a valve regulates the movement of food. (anatomycorner.com)
  • Appendages of fat, containing small blood vessels, called omental appendages (appendices epiploicae) are attached to colon. (medscape.com)
  • This is the small "S" shaped part of the colon, about 40 cm in length, which goes from the bottom of the descending colon into the centre of the pelvis to the rectum . (wikipedia.org)
  • The colon is wider than the small intestine but only about 6 feet long. (limamemorial.org)
  • is the first part of the colon after the small intestine. (limamemorial.org)
  • The examination of the entire length of the colon, up to its juncture with the small intestine, using a flexible tube that has a camera and a light source attached. (oreilly.com)
  • Partly broken down or digested food moves from the small intestine into the colon. (cancer.ca)
  • Diverticulitis is another disease that can affect the ascending colon. (livestrong.com)
  • The greater omentum has several parts, including the 4-layered omental apron hanging down off of the transverse colon and the 2-layered gastrocolic ligament connecting the greater curvature of the stomach and the transverse colon. (medscape.com)
  • It goes underneath the stomach and the pancreas and joins the descending colon near the spleen . (wikipedia.org)
  • The transverse colon hangs off the stomach, attached to it by a wide band of tissue called the greater omentum. (colonoscopyandendoscopybilling.com)
  • The temporary or permanent channeling of the remaining open end of colon through the stomach wall and skin, where an ostomy appliance will attach to capture waste. (oreilly.com)
  • Although dedicated mucosectomy devices, such as cap- or band-assisted EMR, are commonly utilized in the esophagus and stomach, they are avoided in the thin-walled colon due to the high risk of perforation. (mayoclinic.org)
  • The colon is a U-shaped tube made of muscle, found below the stomach. (cancer.ca)
  • The mucosa is the inner lining of the colon and rectum. (cancer.ca)
  • The image at left indicates heat along the ascending colon raising the index of suspicion for irritation/inflammation. (thermogramcenter.com)
  • Such chronic irritation of the lining of the colon can cause ulcers to bleed or ooze pus. (livestrong.com)