Colonic Neoplasms: Tumors or cancer of the COLON.Colon, Descending: The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.Colon, Sigmoid: A segment of the COLON between the RECTUM and the descending colon.Colon, Ascending: The segment of LARGE INTESTINE between the CECUM and the TRANSVERSE COLON. It passes cephalad from the cecum to the caudal surface of the right lobe of the LIVER where it bends sharply to the left, forming the right colic flexure.Colon, Transverse: The segment of LARGE INTESTINE between ASCENDING COLON and DESCENDING COLON. It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon.HT29 Cells: Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS.Azoxymethane: A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.Diverticulum, Colon: A pouch or sac opening from the COLON.Intestinal Mucosa: Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.Colonic Diseases: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.Cell Line, Tumor: A cell line derived from cultured tumor cells.Dimethylhydrazines: Hydrazines substituted with two methyl groups in any position.Colectomy: Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)Colonoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the colon.Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Adenoma: A benign epithelial tumor with a glandular organization.Caco-2 Cells: Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.Sigmoid Neoplasms: Tumors or cancer of the SIGMOID COLON.Rectal Neoplasms: Tumors or cancer of the RECTUM.Carcinogens: Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.Gastrointestinal Motility: The motor activity of the GASTROINTESTINAL TRACT.Rectum: The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Cecum: The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.Dextran Sulfate: Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Mice, Nude: Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.Precancerous Conditions: Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)Butyrates: Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.Anticarcinogenic Agents: Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Intestinal Polyps: Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.Rats, Inbred F344Colitis, Ulcerative: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.Intestine, Large: A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.beta Catenin: A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Colostomy: The surgical construction of an opening between the colon and the surface of the body.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Genes, APC: Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.Cecal Neoplasms: Tumors or cancer of the CECUM.Aberrant Crypt Foci: Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.Sigmoid Diseases: Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Neoplasm Transplantation: Experimental transplantation of neoplasms in laboratory animals for research purposes.Intestines: The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.Carcinoembryonic Antigen: A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.Enema: A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.Mucins: High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.Ileum: The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.Trinitrobenzenesulfonic Acid: A reagent that is used to neutralize peptide terminal amino groups.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Cathartics: Agents that are used to stimulate evacuation of the bowels.Feces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.Intestine, Small: The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Mice, Inbred BALB CTransplantation, Heterologous: Transplantation between animals of different species.Intestinal Neoplasms: Tumors or cancer of the INTESTINES.Cyclooxygenase 2: An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.Neoplasm Proteins: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Microsatellite Instability: The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.Adenomatous Polyposis Coli Protein: A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Diverticulitis, Colonic: Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Diet: Regular course of eating and drinking adopted by a person or animal.Mice, Inbred C57BLBarium Sulfate: A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Dietary Fiber: The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.Sulindac: A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.Muscle, Smooth: Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Methylhydrazines: Hydrazines substituted by one or more methyl groups in any position.Drug Screening Assays, Antitumor: Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.Neoplasm Invasiveness: Ability of neoplasms to infiltrate and actively destroy surrounding tissue.Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.Adenomatous Polyps: Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)Mucin-2: A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.Intestinal Perforation: Opening or penetration through the wall of the INTESTINES.Esophagoplasty: A plastic operation on the esophagus. (Dorland, 28th ed)Neoplasms, Experimental: Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.Digestive System: A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).Megacolon: Dilatation of the COLON, often to alarming dimensions. There are various types of megacolon including congenital megacolon in HIRSCHSPRUNG DISEASE, idiopathic megacolon in CONSTIPATION, and TOXIC MEGACOLON.Epithelial Cells: Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.Anti-Inflammatory Agents, Non-Steroidal: Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Myenteric Plexus: One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)DNA, Neoplasm: DNA present in neoplastic tissue.Xenograft Model Antitumor Assays: In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.Down-Regulation: A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Liver Neoplasms: Tumors or cancer of the LIVER.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Intestinal Absorption: Uptake of substances through the lining of the INTESTINES.Prostaglandin-Endoperoxide Synthases: Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Antigens, Neoplasm: Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.Sigmoidoscopy: Endoscopic examination, therapy or surgery of the sigmoid flexure.Gastrointestinal Contents: The contents included in all or any segment of the GASTROINTESTINAL TRACT.Immunoenzyme Techniques: Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Up-Regulation: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Fatty Acids, Volatile: Short-chain fatty acids of up to six carbon atoms in length. They are the major end products of microbial fermentation in the ruminant digestive tract and have also been implicated in the causation of neurological diseases in humans.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Deoxycholic Acid: A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.DNA Methylation: Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.Colitis, Ischemic: Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.Gastrointestinal Tract: Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Jejunum: The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Levamisole: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Antimetabolites, Antineoplastic: Antimetabolites that are useful in cancer chemotherapy.Isoenzymes: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.Chemotherapy, Adjuvant: Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.Camptothecin: An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.Genes, ras: Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.Defecation: The normal process of elimination of fecal material from the RECTUM.Tumor Suppressor Protein p53: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.Colonoscopes: Specially designed endoscopes for visualizing the interior surface of the colon.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.RNA, Neoplasm: RNA present in neoplastic tissue.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Organoplatinum Compounds: Organic compounds which contain platinum as an integral part of the molecule.Adenoma, Villous: An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)Piroxicam: A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Leucovorin: The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Chlorides: Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Peristalsis: A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.Colonography, Computed Tomographic: A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.Antineoplastic Agents, Phytogenic: Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.Drug Synergism: The action of a drug in promoting or enhancing the effectiveness of another drug.Stomach: An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.Ileostomy: Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.Senna Extract: Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.DNA Mismatch Repair: A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.Cyclooxygenase 2 Inhibitors: A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.Thymidylate Synthase: An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.Intestinal Polyposis: The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).Curcumin: A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.Dinoprostone: The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Submucous Plexus: One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)Microsatellite Repeats: A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).Sialomucins: A subcategory of mucins that contain SIALIC ACID.Gastrointestinal Neoplasms: Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.Cytoskeletal Proteins: Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.Cyclooxygenase Inhibitors: Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.Diverticulosis, Colonic: A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.Bifidobacterium: A rod-shaped, gram-positive, non-acid-fast, non-spore-forming, non-motile bacterium that is a genus of the family Bifidobacteriaceae, order Bifidobacteriales, class ACTINOBACTERIA. It inhabits the intestines and feces of humans as well as the human vagina.Mice, SCID: Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.TCF Transcription Factors: A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.Wnt Proteins: Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.Adenocarcinoma, Mucinous: An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)Proto-Oncogene Proteins: Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.Antigens, Tumor-Associated, Carbohydrate: Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Cocarcinogenesis: The combination of two or more different factors in the production of cancer.Drug Resistance, Neoplasm: Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.Lung Neoplasms: Tumors or cancer of the LUNG.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Distinguishing right from left colon by the pattern of gene expression. (1/37)

Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis. These differences may reflect distinct biological characteristics of proximal and distal colonic mucosa, acquired in embryonic or postnatal development, that determine a differential response to uniformly distributed environmental factors. Alternatively, the differences in the epidemiology of proximal and distal CRCs could result from the presence of different procarcinogenic factors in the ascending versus descending colon, acting on cells with either similar or distinct biological characteristics. We applied cDNA microarray technology to explore the possibility that mucosal epithelium from adult proximal and distal colon can be distinguished by their pattern of gene expression. In addition, gene expression was studied in fetal (17-24 weeks gestation) proximal and distal colon. More than 1000 genes were expressed differentially in adult ascending versus descending colon, with 165 genes showing >2-fold and 49 genes showing >3-fold differences in expression. With almost complete concordance, biopsies of adult colonic epithelium can be correctly classified as proximal or distal by gene expression profile. Only 87 genes were expressed differently in ascending and descending fetal colon, indicating that, although anatomically relevant differences are already established in embryonic colon, additional changes in gene expression occur in postnatal development.  (+info)

Effects of nifedipine and nickel on plateau potentials generated in submucosal interstitial cells distributed in the mouse proximal colon. (2/37)

The effects of nifedipine and nickel ions (Ni2+), known inhibitors of L- and T-type voltage-gated Ca-channels respectively, were investigated on plateau potentials recorded from submucosal interstitial cells distributed in the mouse proximal colon. Plateau potentials were generated at a frequency of about 15 times min(-1) and were formed of two components. The primary component had an initial fast rate of rise with a transient potential (rate of rise, 130 mV/s; peak amplitude, 35 mV) and was followed by a secondary plateau component with a sustained potential (amplitude, 25 mV; duration, 2.6 s). Each cell from which recordings were made was injected with neurobiotin. Subsequent morphological examination with a confocal microscope indicated successful visualization of injected cells only in the presence of 18beta-glycylrhetinic acid (an inhibitor of gap junctional connections), suggesting that these cells were dye-coupled with surrounding cells. The cells injected with neurobiotin exhibited an oval-shaped cell body with bipolar processes and were distributed in the submucosal layer, suggesting that they were submucosal interstitial cells of Cajal (ICC-SM). The plateau potentials were not altered by 0.01 microM nifedipine, but were reduced in duration by 0.1 microM nifedipine, and abolished by 1 microM nifedipine. The rate of rise of plateau potentials, but not their amplitude, was reduced by Ni2+ (> 10 microM), with no significant alteration of the membrane potential. In the presence of 100 microM Ni2+, the plateau potentials were changed to a triangular form. Thus, the plateau potentials were formed by two types of voltage-gated channel current: the initial component was produced by a Ni2+-sensitive channel current and the plateau component by a nifedipine-sensitive current. The possible involvement of two different types of voltage-gated Ca2+-channels in the generation of submucosal pacemaker potentials was discussed.  (+info)

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/37)

1. Mechanisms involved in Ca(2+) sensitization of contractile elements induced by the activation of muscarinic receptors in membrane-permeabilized preparations of the rat proximal and distal colon were studied. 2. In alpha-toxin-permeabilized preparations from the rat proximal and distal colon, Ca(2+) induced a rapid phasic and subsequent tonic component. After Ca(2+)-induced contraction reached a plateau, guanosine 5'-triphosphate (GTP) and carbachol (CCh) in the presence of GTP further contracted preparations of both the proximal and distal colon (Ca(2+) sensitization). Y-27632, a rho-kinase inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization more significantly in the proximal colon than in the distal colon. 3. Y-27632 at 10 microm had no effect on Ca(2+)-induced contraction or slightly inhibited phorbol-12,13-dibutyrate-induced Ca(2+) sensitization in either proximal or distal colon. Chelerythrine, a protein kinase C inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization in the distal colon, but not in the proximal colon. The component of Ca(2+) sensitization that persisted after the chelerythrine treatment was completely inhibited by Y-27632. 4. In beta-escin-permeabilized preparations of the proximal colon, C3 exoenzyme completely inhibited GTP plus CCh-induced Ca(2+) sensitization, but PKC(19-31) did not. In the distal colon, C3 exoenzyme abolished GTP-induced Ca(2+) sensitization. It inhibited CCh-induced sensitization by 50 % and the remaining component was inhibited by PKC(19-31). 5. These results suggest that both protein kinase C and rho pathways in parallel mediate the Ca(2+) sensitization coupled to activation of muscarinic receptors in the rat distal colon, whereas the rho pathway alone mediates this action in the proximal colon.  (+info)

Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/37)

BACKGROUND: Because of their suggested link with microsatellite instability high colorectal cancers, right sided hyperplastic polyps (HPs) may differ from their distally located counterparts. This is highlighted by the recognition of a variant HP, termed sessile serrated adenoma (SSA), which predominates in the proximal colon. HPs displaying the morphological features now associated with SSAs have been shown to have altered expression of "cancer associated" markers, but no studies have investigated whether this is dependent on anatomical location of the polyps. AIMS: To evaluate morphological and functional features in right versus left sided HPs from patients without colorectal cancer with the aim of identifying distinguishing characteristics. METHODS: HPs originating in the proximal and distal colorectum were histochemically and immunohistochemically stained to evaluate a panel of markers related to proliferation and differentiation. In addition, a series of morphological features was evaluated for each polyp. RESULTS: Crypt serration, crypt dilatation, and horizontal crypt growth were more common among HPs from the right side, whereas histochemical factors including mucin changes, global methylation status, and expression of carcinoembryonic antigen were not significantly different. An age disparity was also seen between patients with right versus left sided lesions, with patients with right sided lesions being an average of more than 10 years younger than those with left sided lesions. CONCLUSIONS: These findings suggest that right and left sided HPs differ mainly in terms of growth regulation rather than cellular differentiation, implying that these lesions belong to a continuous spectrum of serrated polyps that differ quantitatively rather than qualitatively.  (+info)

A rare case of ascending colon actinomycosis mimicking cancer. (5/37)

BACKGROUND: Actinomycosis is a rare inflammatory disease caused by an anaerobic bacterium that can rarely affect the large intestine. CASE PRESENTATION: We present a rare case of a cecum and ascending colon actinomycosis in a 72 years old woman, mimicking clinically a malignant inflammatory tumor of the right colon. The patient complained of right lower quadrant pain. Although our first thought was a peri-appendiceal abscess, CT scan suggested a right colon tumor. The patient underwent a right colectomy and the histological examination of the specimen revealed colon actinomycosis. CONCLUSIONS: Preoperative diagnosis in colon actinomycosis is difficult to achieve. Treatment of choice is antibiotics administration. A review of the possible pathogenesis and therapeutic modalities is also presented.  (+info)

Treatment of resistant distal intestinal obstruction syndrome with a modified antegrade continence enema procedure. (6/37)

We report a case of a patient with CF who had a long history of recurrent distal intestinal obstruction syndrome. She had been treated with conventional treatment including gastrografin, n-acetyl cysteine, Klean prep and Picolax. She underwent a modified antegrade continence enema procedure. She currently irrigates her conduit every 2-3 days. She has had no further symptoms of distal intestinal obstruction syndrome.  (+info)

The retroperitoneal surface in distal caecal and proximal ascending colon carcinoma: the Cinderella surgical margin? (7/37)

BACKGROUND: Mesorectal margin tumour involvement is a predictor of local recurrence in rectal carcinoma and an indication for postoperative radiotherapy in suitable patients. However, the prevalence of non-peritonealised surgical margin involvement in ascending colon carcinoma is unknown. AIMS: To test the hypothesis that retroperitoneal surgical margin (RSM) tumour involvement occurs in distal caecal and proximal ascending colon carcinoma. METHODS/RESULTS: One hundred right hemicolectomy specimens, removed for adenocarcinoma of the caecum or proximal ascending colon, were studied. During routine specimen dissection, at least one additional tissue block was taken to include the tumour and the RSM. The tumour distance from the RSM was recorded. RSM tumour involvement was present in seven cases (7%). Direct (non-nodal) RSM tumour involvement (five cases) only occurred in posterior or circumferential tumours. CONCLUSIONS: RSM tumour involvement occurs within a considerable number of distal caecal and proximal ascending colon carcinomas. The rate of RSM tumour involvement identified here is similar to a previously published local recurrence rate of 10% in caecal carcinoma, suggesting that RSM tumour involvement may be a predictor of recurrence in these tumours. Therefore, patients with distal caecal or proximal ascending colon carcinoma and RSM tumour involvement may benefit from postoperative radiotherapy.  (+info)

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (8/37)

BACKGROUND: Despite the fact that the alimentary tract is part of the body's first line of defense against orally ingested xenobiotica, little is known about the distribution and expression of cytochrome P450 (CYP) enzymes in human colon. Therefore, expression and protein levels of four representative CYPs (CYP2C(8), CYP2E1, CYP3A4, and CYP3A5) were determined in human colon mucosa biopsies obtained from ascending, descending and sigmoid colon. METHODS: Expression of CYP2C, CYP2E1, CYP3A4, and CYP3A5 mRNA in colon mucosa was determined by RT-PCR. Protein concentration of CYPs was determined using Western blot methods. RESULTS: Extensive interindividual variability was found for the expression of most of the genes. However, expression of CYP2C mRNA levels were significantly higher in the ascending colon than in the sigmoid colon. In contrast, mRNA levels of CYP2E1 and CYP3A5 were significantly lower in the ascending colon in comparison to the descending and sigmoid colon. In sigmoid colon protein levels of CYP2C8 were significantly higher by ~73% than in the descending colon. In contrast, protein concentration of CYP2E1 was significantly lower by ~81% in the sigmoid colon in comparison to the descending colon. CONCLUSION: The current data suggest that the expression of CYP2C, CYP2E1, and CYP3A5 varies in different parts of the colon.  (+info)

Background Up to 50% of septic patients develop acute kidney injury (AKI). The pathomechanism of septic AKI is poorly understood. Therefore, we established an innovative rodent model to characterize sepsis-induced AKI by standardized colon ascendens stent peritonitis (sCASP). The model has a standardized focus of infection, an intensive care set up with monitoring of haemodynamics and oxygenation resulting in predictable impairment of renal function, AKI parameters as well as histopathology scoring. Methods Anaesthetized rats underwent the sCASP procedure, whereas sham animals were sham operated and control animals were just monitored invasively. Haemodynamic variables and blood gases were continuously measured. After 24 h, animals were reanesthetized; cardiac output (CO), inulin and PAH clearances were measured and later on kidneys were harvested; and creatinine, urea, cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) were analysed. Additional sCASP-treated animals were investigated
RESULTS: Continence was achieved in 98% of patients. Followup was 6 to 71 months (mean 28.4). There were 27 channel related complications (23%). Stomal stenosis occurred in 7 antegrade continence enema procedures (14%) within 1 to 10 months (mean 6.2) and in 9 continent bladder channels (13%), including 5 continent cutaneous vesicostomies, within 1 to 24 months (mean 9.4) after surgery. False passages occurred in 5 antegrade continence enema procedures (10%) within 1 to 13 months (mean 3.6) and in 4 continent catheterizable channels (6%) within 1 to 13 months (mean 6.5) after surgery. Of patients with stomal stenosis 50% were treated with surgical revision, while the remainder was successfully treated with dilation. Most false passages were managed by catheter drainage alone. Reasons for revision were contained perforation, colovesical fistula and inability to catheterize. Patient noncompliance appeared to have a role in stomal stenosis ...
Video articles in JoVE about acute kidney injury include Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish, Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice, Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury, Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury, Intravenous Microinjections of Zebrafish Larvae to Study Acute Kidney Injury, Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney, Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration, Kidney Regeneration in Adult Zebrafish by Gentamicin Induced Injury, Isolation of Double Negative αβ T Cells from the Kidney, Techniques to Assess Kidney Function in Mouse Models of Glomerular Disease, Use of a Hanging-weight System for Isolated Renal Artery Occlusion, Phenotypic Characterization of Macrophages from Rat Kidney
The ascending colon is the part of the colon located between the cecum and the transverse colon. The ascending colon is smaller in calibre than the cecum from where it starts. It passes upward, opposite the colic valve, to the under surface of the right lobe of the liver, on the right of the gall-bladder, where it is lodged in a shallow depression, the colic impression; here it bends abruptly forward and to the left, forming the right colic flexure (hepatic) where it becomes the transverse colon. It is retained in contact with the posterior wall of the abdomen by the peritoneum, which covers its anterior surface and sides, its posterior surface being connected by loose areolar tissue with the iliacus, quadratus lumborum, aponeurotic origin of transversus abdominis, and with the front of the lower and lateral part of the right kidney. Sometimes the peritoneum completely invests it and forms a distinct but narrow mesocolon. It is in relation, in front, with the convolutions of the ileum and the ...
A 69 year old lady attended for a colonoscopy under the UK Bowel Cancer Screening Programme having been found to be FOB ve using the Guaiac test. A large LST-G was found in the ascending colon ...
Several diseases can affect the ascending colon, or first part of your large intestine. If youre experiencing pain in this area, heres what you should know.
The ICD-10 Code C18.2 is the code used for Malignant neoplasm of ascending colon .An alternative description for this code is Malignant neoplasm of ascending ...
Modification #1. (To follow Step #4 if barium has not reached the ascending colon.) Turn the patient 360° in each direction. When the patient is again prone, take another look. If barium is now in the ascending colon, proceed to Step #5; if not, go to Modification #2. (NOTE: Do not insufflate additional air at this point, as it will likely produce an air-lock in the cecum ...
Diagnosis Code D3A.022 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
A 67-year-old man who presented with a bloody stool was diagnosed with ascending colon cancer. He had previously experienced thoracic and abdominal aortic dissections, which were treated with thoracic and abdominal aortic grafts and superior mesenteric artery revascularization. We performed a laparoscopic right hemicolectomy with a D3 lymph node dissection. During the laparotomy, we identified the superior mesenteric artery and an enlarged anterior superior pancreaticoduodenal artery. Injury to the latter artery could lead to severe ischemia in multiple organs; therefore, it was crucial to identify the primary feeding artery and vascular anatomy before and during surgery ...
PET demonstrated a large mass with intense FDG uptake in the right hilum corresponding to the patients known carcinoma. Peripheral to the large mass is a wedge-shaped area of mildly increased FDG uptake due to the adjacent post-obstructive pneumonitis as evidenced in the CT of the chest. In addition, there is intense FDG activity in the abdomen and pelvis conforming to small bowel loops in the initial PET imaging. Further delayed PET imaging of the abdomen and pelvis showed progression of the FDG into the distal ileum, cecum and proximal ascending colon. Mild FDG uptake in the left chest wall is of uncertain significance. This may be due to prior trauma, but there is no focal abnormality identified on CT in that region ...
TY - JOUR. T1 - Ureteral replacement with reconfigured colon substitute. AU - Pope, John. AU - Koch, Michael. PY - 1996/5. Y1 - 1996/5. N2 - Purpose: Upper ureteral defects are often too extensive to repair by direct anastomosis or with use of a bladder flap. Ureteral substitution may be the only remaining alternative to restoring urinary drainage from the kidney to the bladder. This effect is usually achieved by interposing a segment of small bowel between the proximal collecting system and bladder. If ileum is not available other substitution alternatives must be sought. Materials and Methods: We report a new technique in which a tube constructed from a small piece of ascending colon was used to replace a large ureteral defect. Results: Excellent short-term results were achieved by replacing the strictured ureteral segment with a reconfigured colon segment as shown by symptomatic and radiographic improvement. Conclusions: A reconfigured colon segment can be used for ureteral reconstruction in ...
Ascending Colon Membrane Lysate Catalog Number: XBL-10523 By Type: Tissue Species: Human Diagnosis: Normal Tested Applications: WB Size: 0.1 mg ...
The Colon Care Centre does not promote water fasts for the obvious reason that we want the body to be eliminating toxins from the liver, kidneys, lymphatic system, skin and colon whilst you are preparing for your ultimate in colon cleansing. Water fasting shuts down the bodys eliminating process holding back the toxins because it is undergoing a negative feedback reaction which means the body will not generally respond until there is a variation from the normal.. While you are juice fasting we are promoting total alkalinity to feed the cells whilst responding in lowering acidity, candida and cleansing each cell in the body.. During the 1st, 2nd, 3rd day of your vegetable juice fasting your body is eliminating toxins and the bowels own peristalsis is being activated giving great results before the colonic treatment.A colonic treatment is to be performed on the 4th day of your juice fasting. We support your detox by increasing the hydration within the descending , transverse and ascending colon ...
With patient lying supine, the evaluation with the duodenum with superior frequency ultrasound duodenography is executed with seven.five MHz probe positioned in the correct upper abdomen, and central epigastric successively; for high frequency ultrasound colonography, the ascending colon, is examined with start line normally midway of an imaginary line managing from your iliac crest for the umbilicus and proceeding cephalid throughout the appropriate mid abdomen; with the descending colon, the assessment begins through the still left higher abdomen proceeding caudally and traversing the still left mid abdomen and left reduce abdomen, terminating with the sigmoid colon in the lower pelvic area. Shade movement Doppler sonography is utilized to examine the localization of lesions in relation to vessels. All measurements of diameter and wall thickness are performed with developed-in application. Measurements are taken concerning peristaltic waves.[45 ...
With affected person lying supine, the examination of the duodenum with significant frequency ultrasound duodenography is executed with 7.five MHz probe positioned in the appropriate upper abdomen, and link central epigastric successively; for top frequency ultrasound colonography, the ascending colon, is examined with start line generally halfway of an imaginary line jogging from the iliac crest into the umbilicus and continuing cephalid through the suitable mid abdomen; to the descending colon, the evaluation commences through the remaining higher abdomen proceeding caudally and traversing the remaining mid abdomen and left lessen abdomen, terminating in the sigmoid colon during the reduce pelvic region. Coloration flow Doppler sonography is employed to look at the localization of lesions in relation to vessels. All measurements of diameter and wall thickness are executed with developed-in software program. Measurements are taken between peristaltic waves.[forty five ...
An 18-year-old male patient presented with a cold abscess affecting his wrist and subsequently developed diarrhoea. The DCBE erect view shows contraction of the ascending colon and, in particular, the caecum. The ileocaecal valve is irregularly contracted (arrows) and the distal 2cm of the terminal ileum is irregular in outline, with at least one short sinus track. Acid-fast bacilli were isolated from the cold abscess and from the colon ...
Lynch syndrome (LS), former known as Hereditary Non Polyposis Colorectal cancer (HNPCC), accounts for 3-5% of all colorectal cancers (CRC) and is inherited in an autossomal dominant fashion. This syndrome is characterized by early CRC onset, high incidence of tumors in the ascending colon, excess of synchronous and metachronous tumors, and accelerated transition adenoma-carcinoma (2-3 years). Nowadays, LS is regarded of patients who carry deleterious germline mutations in one of the five Mismatch repair genes, such as MutL homolog 1 (MLH1), MutS homolog 2 (MSH2), MutS homolog 6 (MSH6), post-meiotic segregation increased 1 (PMS1) or post-meiotic segregation increased 2 (PMS2). In order to characterize Brazilian patients suspect for LS, we assessed the frequency of germline point mutations in MSH6, PMS1 and PMS2 in patients negative for point mutations in MLH1 and MSH2 by capillary sequencing. We also assessed chromosomal deletions in MLH1 and MSH2 and MSH6 generating a complete characterization ...
The life cycle of the parasites are so interesting. The pinworm life cycle is pretty simple. They are ingested by fecal-oral contact, the eggs hatch in the duodenum, the larvae molt a couple of times on their way down to the cecum and ascending colon where they mate. Gravid females migrate to the anus at night where they release their eggs and maybe cause some pruritis ani. Superinfection may occur from there and the "scotch-tape test" may catch them for diagnosis. You guys nailed it, the treatment is mebendazole 100mg po once ...
Radiates from ear, lumbago, radiation in appendages, bladder, pelvis & groin, pain inner knee, deep lumbago, sacroiliac syndromes, servo-steering of osmosis, dialysis, turbulence & thermal, sleep & waking state, arteries.. Ascending colon.. [toothbooks]. ...
TY - JOUR. T1 - Aorta ascendens álaneurysma mély hypothermiában keringés leállítással végzett sikeres mütéte.. AU - Szabó, Z.. AU - Rényi-Vámos, F.. AU - Bodor, E.. AU - Kalmár, I.. AU - Gyöngy, T.. AU - Papp, L.. PY - 1984/12/9. Y1 - 1984/12/9. UR - http://www.scopus.com/inward/record.url?scp=17644432166&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=17644432166&partnerID=8YFLogxK. M3 - Article. C2 - 6514347. AN - SCOPUS:17644432166. VL - 125. SP - 3053. EP - 3056. JO - Orvosi Hetilap. JF - Orvosi Hetilap. SN - 0030-6002. IS - 50. ER - ...
Contents: General Principles. Preparation for colorectal surgery .Safety and positioning in the operating room. Access to abdominal cavity - open. Access to abdominal cavity - laparoscopic. Access to abdominal cavity - hand-assisted laparoscopic surgery. Single incision laparoscopic-assisted colectomy. Access to the abdominal cavity: natural orifice transluminal endoscopic surgery. Anastomotic technique - suture. Anastomotic technique - stapled. Specimen handling. Proctology. Office/outpatient set up. Proctosigmoidoscopy. Flexible endoscopy. Treatment of uncomplicated haemorrhoids. Excision of perianal thrombosis. Open hemorrhoidectomy. Closed hemorrhoidectomy. Stapled hemorrhoidopexy. Perianal sepsis. Anal fistula. Rectovaginal fistula repair. Anal fissure. Anoplasty. Perianal condyloma and anal intraepithelial neoplasia. Perianal skin and anal cancer Pilonidal disease. Stomas. Ileostomy. Colostomy. Stoma closure. Antegrade continence enema procedure in children. Antegrade continent enema ...
By Patel, Vijaykumar G Rao, Arundathi; Williams, Reginald; Srinivasan, Radha; Et al Acute epiploic appendagitis (EA) is a rare and often misdiagnosed cause of acute abdominal pain. Though a benign and often self- limiting condition, EAs ability to mimic other disease processes makes it an important consideration in patients presenting with acute abdominal symptoms. Careful evaluation of abdominal CT scan findings is crucial in the accurate diagnosis of epiploic appendagitis, thus avoiding unnecessary surgical intervention. We report a case of a 29-year-old male presenting with a two day history of generalized abdominal pain. Physical exam revealed a diffusely tender abdomen with hypoactive bowel sounds. The patient had a leukocytosis of 18,000 and abdominal CT scan revealed right lower quadrant inflammatory changes suggestive of acute appendicitis. Laparoscopic exploration revealed an inflamed gangrenous structure adjacent to the ileocecal junction. Pathologic evaluation revealed tissue ...
Free, official information about 2011 (and also 2012-2015) ICD-9-CM diagnosis code 209.53, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
Channing rescues Jupiter, who is now free to live in a palace and rule the Universe, but she decides to go back home and scrub commodes, because its a little late in the movie to start pretending shes smart. On the bright side, her annoying family unexpectedly turns nice and gives her a telescope so shell get murdered by Russian gangsters, and Channing gets his wings, just like Clarence in Its a Wonderful Life, and promptly uses them to make out in mid-air with Jupiter, just like Clarence did with George Bailey. So everybody got what their hearts desire, I guess, except me. I wanted a thrilling yet thoughtful science fiction epic in the vein of The Matrix. What I got was the worlds longest commercial for the Chlorox Toilet Wand ...
Therapy of epiploic appendagitis is a topic of some controversy. It is described by some authors as a self-limiting condition with patients recovering in less than 10 days with oral anti-inflammatory medication [22]. Most of the surgical literature underlines the benign course of disease and favors a conservative therapy regiment. This is a widely applied form of therapy which is practiced with success. However, we have observed that there is a tendency of recurrence in conservatively treated patients. Four of ten patients in this study (40%) already had the same pain at the same localization, for two days on average, four weeks before presenting to the emergency department. This cannot be taken as decisive evidence that EA recurs if not treated surgically. Nevertheless it arouses suspicion that conservative forms of therapy might have a tendency for recurrence and surgical interventions should be considered. In the authors personal opinion surgical therapy is favorable to prevent recurrence, ...
Epiploic appendagitis is usually seen in middle-aged men with a history of diabetes. They are an important cause of abdominal pain since they are managed with supportive care only and do not require a laparotomy.
Appendagitis epiploic - What is epiploic appendagitis? The great pretender! Epiploic appendices are tear-drop shaped projections of fat that are attached to the outer wall of the large intestine. They have a propensity to twist, which may cut-off its blood supply and cause acute pain. This is a self-limiting condition that does not require any treatment. When this occurs on the right side, it is often mistaken for appendicitis, unless a skilled radiologist finds this on ct.
Caecal volvulus is an infrequent clinical condition caused by an axial twist of ascending colon, caecum and terminal ileum around the mesenteric pedicle. This article presents the case of a 16 year old African male from Kenya who presented to the emergency department with acute onset right sided lower abdominal pain diagnosed intra-operatively as caecal volvulus. The rare nature of the condition, the need for a high index of suspicion and surgical management are highlighted.
Peristalsis is a rhythmic and symmetrical contraction and relaxation of the colon to move waste from the body. Often, due to dehydration, over-use of laxatives, stress, or Colitis, Crohns or IBS, this movement doesnt work in the way it should.. Learning the 9-Part Abdominal Exercises can restore this function resulting in regular bowel movements, release of gas and abdominal cramping, and relief from debilitating symptoms.. The colon has different segments: the cecum, the ascending colon, the hepatic angle, the transverse colon, the splenic angle, the descending colon, and the sigmoid colon. In the 9-Part Abs, one "massages" each segment separately in order to enable the parts to work seamlessly as a whole.. ...
This medical exhibit pictures an anterior (front) view of the normal anatomy of the large and small intestines. Labels are provided for the duodenum, ascending colon, terminal ileum, cecum, transverse colon, descending colon, sigmoid colon and rectum. This illustration also shows the liver and stomach.
Colon lavement - Radio-Anatomie - Titre: Radio-Anatomie - Colon lavementDiagnostic: Colon lavementHôpital: HUGDépartement: AnatomieDate: 21.03.2003ID: 3460Chapitre: AbdomenDescription: DESCRIPTION: 1) Caecum (Coecum) 2) Côlon ascendant(Colon ascendens) 3) Angle colique droit (Flexura coli dextra) 4)Côlon transverse (Colon transversum) 5) Angle colique gauche(Flexura coli sinistra) 6) Impression splénique et bord de la rate7)... - 1211492105 - Geneva University Hospital
PICTURES IN DIGESTIVE PATHOLOGY. Anorectal melanoma associated with colonic metastasis. Melanoma anorrectal asociado a metástasis colónicas. Macarena Fernández-Albornoz, Joaquín Irarrázaval-Espinoza, Andrés Larach-Kattan and Leonardo Espíndola-Silva. Hospital Militar. Santiago, Chile. Case report. A 67-year-old female patient with no medical history presents with pain and increased volume in her right lower limb for the last three weeks. She is admitted with a diagnosis of right-side iliac-femoral-popliteal deep venous thrombosis and bilateral pulmonary thromboembolism. She developed rectorrhagia following anticoagulation. Colonoscopy revealed an exophytic, mamillated, friable, anteriorly ulcerated lesion from the anal margin to the mid rectum (Fig. 1), two lesions with similar characteristics in the ascending colon, and three such lesions at the ileocecal valve (Fig. 2). Histopathology and immunohistochemical studies are consistent with melanoma. Abdominal and pelvic CT and MRI scans ...
Large LST of the ascending colon. Previous biopsies show adenoma with low grade displasia. Author: Dr. Franco Orellana, Chile. ...
... this image shows the anatomy of the git from the small intestine to the anus.displaying their position and relation to each other and to the rest of the body. showing: 1. esophagus 2. liver 3. stomach 4. small intestine 5. ascending colon 6. descending colon 7. tr
Proper digestion has the ability to make or break ones holistic wellness. Digestion is the nucleus of our energy regulation, and we dont operate well when were feeling sluggish, bloated, or queasy. Optimal digestion leads to regular elimination, which is the bodys natural way of flushing out toxins and waste. At the risk of TMI, lets just say that without regular elimination were left in a very yucky, heavy state!. As yogis, we know especially well how uncomfortable it is to practice when full, bloated, queasy or constipated. So here are three simple, easy ways yoga can improve your digestion.. 1. Apanasana. Apanasana, knees hugged to belly, is known as the "wind-relieving pose." Hugging the right knee into the belly massages the ascending colon, while hugging the left knee in massages the descending colon. Try this simple pose for improved digestion:. Come to lie on the back. Settle into your yoga mat or wherever you are. Place your feet to the floor, directly beneath the knees. On an ...
Cancers on the appropriate side of the massive intestine (ascending colon and cecum) tend to be exophytic, which is, the tumor grows outwards from a person location while in the bowel wall.The higher prerequisite for observe-up colonoscopy that has a FOBT programme does have to have a large amount of means to be put into gastroenterological solutio… Read More. ...
RiTradiology.com ดูแลรักษาโดยและเป็นของ น.พ.รัฐชัย แก้วลาย. โลโก้ RiTradiology.com เป็นลิขสิทธิ์ของ น.พ.รัฐชัย แก้วลาย. ข้อมูลส่วนตัวของคุณถือเป็นความลับและจะไม่ถูกเผยแพร่ไปยังบุคคลที่สาม. ข้อมูลใน RiTradiology.com ใช้เป็นแนวทาง, ไม่ใช่เพื่อทดแทน, การให้การวินิจฉัย, รักษาและคำแนะนำสำหรับผู้ป่วย. แพทย์ของคุณอาจให้คำแนะนำในการวินิจฉัยหรือรักษาเป็นอย่างอื่นขึ้นกับข้อมูลและสถานการณ์นั้นๆ. ...
Epipterygium Lindb., Öfvers. Förh. Kongl. Svenska Vetensk.-Akad. 19: 603. 1862. Plants small, dull or glossy, pale, glaucous-green to pinkish or reddish green in loose tufts; stems forked or simple; rhizoids sparse, reddish brown, lightly papillose. Leaves dimorphic, lateral leaves in 2-3 rows, obovate to broadly elliptic, acute, sometimes decurrent, dorsal leaves in 1-3 rows, smaller and narrower than the lateral leaves, lanceolate to linear-lanceolate acute to shortly acuminate; margins bordered or elimbate, plane, entire to obscurely serrulate above; costa ½ to _ the leaf length in lateral leaves, shorter in dorsal leaves; cells broadly rhombic, rhomboidal or linear, lax or firm, thin-walled, alar cells undifferentiated. Dioicous. Perigonia terminal, bud-like. Setae reddish orange, smooth. Capsules cylindrical to pyriform, inclined to pendent; exothecial cells collenchymatous; stomata superficial; opercula conic-apiculate; annuli rudimentary or revoluble; peristome double, exostome densely ...
TY - JOUR. T1 - Localized malignant peritoneal mesothelioma arising in the mesentery of the ascending colon. AU - Kim, Younghye. AU - Lee, Eunjung. AU - Jung, Wonkyoung. AU - Kim, Han Kyeom. AU - Jung, Soon Hee. AU - Hong, Kwang Dae. AU - Lee, Youngseok. PY - 2012/5/1. Y1 - 2012/5/1. UR - http://www.scopus.com/inward/record.url?scp=84862862365&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84862862365&partnerID=8YFLogxK. M3 - Article. C2 - 22546096. AN - SCOPUS:84862862365. VL - 78. JO - American Surgeon. JF - American Surgeon. SN - 0003-1348. IS - 5. ER - ...
False-colour barium enema X-ray of the human abdomen showing a cancer of the ascending colon; the tumour appears as the oval shadow over the right pelvic bone (left on image). Opaque to X- rays, barium is given orally (barium meal) for investigations of the oesophagus, stomach & duodenum and rectally (as a barium enema) to examine the rectum & colon. The colon (large intestine) consists of four sections - the ascending, transverse, descending and sigmoid colons. Here, the ascending colon rises at left, its transverse (horizontal) section appears in centre, and the descending part at right, which connects with the rectum via the sigmoid colon. - Stock Image M134/0099
Patients with concurrent chronic ulcerative colitis and primary sclerosing cholangitis or patients with chronic ulcerative colitis and known colorectal dysplasia or cancer, presenting for surveillance colonoscopy will be recruited. After giving informed consent patients will then undergo colonoscopy in a segmental fashion. Colonoscopy with white light will be performed to the cecum and examination will be performed on withdrawal. First conventional white light will be used to examine the cecum and ascending colon and random biopsies will be obtained. All endoscopically apparent lesions will be biopsied separately. Immediately following will be examination of that segment of cecum and ascending colon under AFI first, then NBI with targeted biopsies of suspicious areas being taken. The AFI and NBI modality will be achieved by simply flipping a switch.. If necessary, washing of oozing blood from random biopsy sites will be performed., The remainder of the colon will be assessed in like fashion: ...
We describe the macroscopic anatomy of the intestine of the giraffe (Giraffa camelopardalis). The small intestine was divided into duodenum, jejunum and ileum as usual. The caecum was attached to the ileum by a long ileocaecal fold, and to the proximal ansa of the ascending colon by a caecocolic fold. The ascending colon was the most developed portion of the gross intestine and had the most complex arrangement with three ansae: the proximal ansa, the spiral ansa and the distal ansa. The proximal ansa completely encircled the caecum, describing a 360° gyrus, and represented the widest portion of the intestine. The spiral ansa was formed by three and a half centripetal gyri, a central flexure and three centrifugal gyri. The last centrifugal gyrus left the spiral and described nine flexures of different form and direction over the ...
Diagnosis Code C7A.022 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
List of 194 causes for Abdominal Cramps in Pregnancy and Right lower quadrant pain in children and Urination pain, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
Surgical resection remains the only curative treatment for patients suffering from colorectal liver metastases, but only 15-25% of patients are initially eligible for resection. The majority of patients suffering from colorectal liver metastases receives chemotherapy prior to liver surgery in order to downsize the colorectal liver metastases. Preoperative treatment with oxaliplatin-based chemotherapy is related to sinusoidal injury, the so-called sinusoidal obstruction syndrome. Patients with histologically proven sinusoidal injury undergoing liver surgery have a higher risk of post-resectional morbidity. Damage to the hepatic sinusoids is a key factor for the development of the sinusoidal obstruction syndrome. Anticoagulants (i.e. salicylates, clopidogrel, low-molecular weight heparin, or coumarin derivates) might be able to prevent this damage and, consequently, the development of the sinusoidal obstruction syndrome in patients suffering from colorectal liver metastases treated with ...
Sprawdź ile zapłacisz za lek Lisdexamfetamine Dimesylate w aptece, znajdź tańsze zamienniki leku. Określ swoje uprawnienia i sprawdź jakie zniżki Ci przysługują.
Abdominal Distension, Dissociative Amnesia, Left Lower Quadrant Pain Symptom Checker: Possible causes include Acute Gastroenteritis, Ovarian Cyst, Constipation. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
In no surgical procedure has the practice of standardizing the incision proved more harmful. There can be no incision that should always be utilized, since the appendix is a mobile part of the body and may be found anyplace in the right lower quadrant, in the pelvis, up under the ascending colon, and even, rarely, on the left side of the peritoneal cavity (figures 1 and 3). The surgeon determines the location of the appendix, chiefly from the point of maximum tenderness by physical examination, and makes the incision best adapted for exposing this particular area. The great majority of appendices are reached satisfactorily through the right lower muscle-splitting incision, which is a variation of the original McBurney procedure (figure 1, incision A). If the patient is a woman and laparoscopic evaluation is not available, many surgeons prefer a midline incision to permit exposure of the pelvis. If there is evidence of abscess formation, the incision should be made directly over the site of the ...
The colon extends from the end of the ileum to the rectum. The cecum, ascending colon, hepatic flexure, and proximal transverse colon comprise the right colon. The distal transverse colon, splenic flexure, descending colon, sigmoid colon, and rectosigmoid comprise the left colon (Figure 30-1). The ascending and descending portions are fixed to the retroperitoneum, and the transverse colon and sigmoid colon are suspended in the peritoneal cavity by their mesocolons. The caliber of the lumen is greatest at the cecum and diminishes distally. The wall of the colon has four layers: mucosa, submucosa, muscularis, and serosa (Figure 30-2). The muscularis propria consists of an inner circular layer and an outer longitudinal layer. The longitudinal muscle completely encircles the colon in a very thin layer, and at three points around the circumference it is gathered into thick bands called taeniae coli. Sacculations (haustra) are the result of shortening of the colon by the taeniae and contractions of ...
Before talking about colon cancer prevention, lets talk a little about what colon cancer is, exactly. Both the colon and rectum are part of the digestive system. The first part of the digestive system, which is the esophagus and stomach, breaks down food to be processed into energy. Next, the broken down food travels to the small intestine/bowel, which is a narrow, 20-foot section that continues breaking down food and absorbing most of the nutrients. The small intestine then sends the remaining material to the five-foot-long colon (which is also referred to as "the large intestine"), where it absorbs salt and water and stores waste. The first part of the colon is the ascending colon, which is attached to the small intestine and the appendix on the right side of the abdomen. The transverse colon runs from the right to the left side of the upper abdomen. The descending colon travels downward on the left side and the sigmoid colon is an S-shaped portion that passes food matter down to the rectum, ...
From the small bowel, the residual material drains into the large intestine (or colon). The colon is about 6 feet in length and begins with the cecum, extends into the ascending colon, the transverse colon, the descending colon, the sigmoid colon and finally the rectum and anus. The function of the colon is to absorb water and salts and bacteria also interacts with the liquid waste matter in the colon assisting with the conversion to feces or stool. This interaction with bacteria contributes to the formation of gas or flatus. Stool is stored primarily in the descending colon and sigmoid colon where it moves into the rectum ...
Cross Sectional Anatomy Body. Rad T 270. L1 A. external oblique B. right costal carightilage C. rectus abdominus D. transverse colon E. transverse colon F. ascending colon G. pancreas - head H. duodenum - 2nd part I. inferior vena cava J. diaphragm K. psoas major L. renal pyramid. Slideshow 4521940 by hester
Large and small intestines(bowels) with blood vessels. The image reveals the blood supply to the abdomen, including the jejunum, ileum, ascending colon, transverse colon, descending colon, the appendix, as well as the greater omentum which covers the abdominal contents. The arterial supply to the abdomen originates from the superior mesenteric artery. This image is intentionally left unlabeled to accommodate custom label requests.
Healthy caecum. Endoscopic view of a healthy large intestine, showing the wall of the caecum. The caecum is a pouch connected to the ascending colon, and is considered to be the beginning of the large intestine. The large intestine is mainly responsible for extracting water and salt from solid wastes before they are eliminated from the body. - Stock Image C001/2421
The unembryonated eggs are passed with the stool. In the soil, the eggs develop into a 2-cell stage, an advanced cleavage stage, and then they embryonate; eggs become infective in 15 to 30 days. After ingestion (soil-contaminated hands or food), the eggs hatch in the small intestine, and release larvae that mature and establish themselves as adults in the colon. The adult worms (approximately 4 cm in length) live in the caecum and ascending colon. The adult worms are fixed in that location, with the anterior portions threaded into the mucosa. The females begin to oviposit 60 to 70 days after infection. Female worms in the caecum shed between 3,000 and 20,000 eggs per day. The life span of the adults is about 1 year.. ...
The first line of treatment for mild to moderate extensive UC consists of oral aminosalicylates (ASAs) with oral controlled release budesonide or prednisone as an alternative. Mesalamine or corticosteroid enemas or suppositories are preferred for distal disease. Mesalamine is less effective for CD. Controlled-release budesonide or a tapering course of prednisone with or without azathioprine is preferred as a first-line agent for mild to moderate CD confined to the terminal ileum and/or ascending colon. Patients with more diffuse disease can be managed by a tapering course of prednisone with or with azathioprine. ...
Schwannomas are homogenous tumors of Schwann cells. These cells insulate the peripheral nerves and allow rapid transmission of impulses between CNS and periphery. They produce symptoms by impinging on the nerves. Mostly schwannoma occur in peripheral nerves of head and neck region. Rarely these are seen in the GIT.. The GIT schwannomas have a tendency to ulcerate, bleed, enlarge and cause obstruction. The chance of malignant transformation is 0.3% (2). These tumors also exist with other extra and intra-intestinal tumors; primary adeno-carcinoma of ascending colon (3). An association with Hodgkin Lymphoma and Von Recklinghausen disease was reported by Qasi et al. (2). Despite occurring in the submucosal layer of GI tract they can enlarge up to 120mm in size and cause obstruction (4).. The exact etiology of schwannomas is not known. We hypothesize that chronic irritation of GI lining which leads to stimulation of Schwann cell over growth can contribute to the formation of schwannoma since the ...
CASE 297.-Private Henry Miller, company I, 26th Michigan volunteers; admitted February 1, 1864, from the army of the Potomac. Chronic diarrhœa. [It appears from the register of the regimental hospital of the 26th Michigan volunteers, that this man was treated in that hospital, then near Stevensburg, Virginia, for diarrhœa from January 14th to February 1st.] Died, February 6th. Autopsy: Emaciation extreme. The right lung normal; in the left lung there were from ten to fifteen patches of lobular pneumonia from the size of a chestnut to that of a hens egg. The heart was normal. The pericardium contained half an ounce of serum. Liver normal. The spleen somewhat enlarged. The pancreas indurated. The stomach, duodenum, jejunum, and the upper three-fourths of the ileum were healthy; the lower fourth was injected, and its mucous membrane softened. The ascending colon was healthy; the remainder of the large intestine was highly injected, and presented numerous ulcers, particularly in the sigmoid ...
Effect of Anatomical Distribution of Mast Cells on Their Defense Function against Bacterial Infections: Demonstration Using Partially Mast Cell deficient tg/tg ...
Lexington, Massachusetts (ots/PRNewswire) - Labeling Update Based on Maintenance of Efficacy Data from a 38-Week Phase 3 Study For U.S. Audiences Only - Shire plc (LSE: SHP,...
We report a case of primary sarcoma of the skin with a biphasic histological pattern, being composed of areas of mixed mesenchymal-epithelial cell proliferation and areas of purely sarcomatous growth. The tumor occurred in the posterior cervical region of a 93-year-old man, and its history was marked by sudden, rapid enlargement after many years of stable duration. The excised lesion was about 4 cm in diameter, had a firm consistency and was covered by intact skin. Histological examination showed a multifocal proliferation of follicular germinative cells arranged in corymbiform and petaloid shapes with an overall retiform growth pattern. Epithelial cords and strands were composed of cytologically uniform cells with bland nuclear features and were surrounded by a prominent, fibroblast-rich stroma reminiscent of a perifollicular sheath. In many areas of the tumor the stroma showed abrupt transition into a pleomorphic proliferation of large sarcomatous cells with frequent and often atypical ...
Learn about Vyvanse (Lisdexamfetamine Dimesylate) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and. 3
12 May 1995 MOLASSESMOLASSES should be applied at 9-18 litres/t of silage, says Dr Keady. The aim is to supply sugar so indigenous bacteria convert it
Objective: To evaluate lisdexamfetamine dimesylate maintenance of efficacy in adults with attention-deficit/hyperactivity disorder (ADHD).. Method: Adults (aged 18-55 years) who had ADHD meeting DSM-IV-TR criteria, baseline ADHD Rating Scale-IV (ADHD-RS-IV) with adult promptstotal scores of ,22, and Clinical Global Impressions-Severity of Illness (CGI-S) ratings of 1, 2, or 3 were enrolled. After previously receiving commercially available lisdexamfetamine dimesylate (30, 50, or 70 mg/d) for ≥6 months with acceptable tolerability and maintaining response during a 3-week open-label phase at a stable lisdexamfetamine dimesylate dose, the participants entered a 6-week double-blind randomized withdrawal phase on treatment with lisdexamfetamine dimesylate (same dose) or placebo. Data were collected from April 2009 to July 2010. The primary outcome was the proportion of participants having symptom relapse (≥50% increase in ADHD-RS-IV score and ≥2 rating-point increase in CGI-S score).. Results: ...
SRUS is a rare benign condition where individuals experience difficult defecation. It is characterized by mucosal prolapse, tenesmus, rectal bleeding, constipation, and the passage of mucus, or rectal pain. The patient in the current case predominately experienced abdominal pain and gastrointestinal hemorrhaging. Previously, SRUS and MPS were not considered as separate conditions. In recent articles, however, SRUS is categorized as a type of MPS, whereas MPS is classified as a category of the bowel diseases consisting of rectal prolapse, inflammatory cap polyp, proctitis cystica profunda (PCP), inflammatory cloacogenic polyp, inflammatory myoglandular polyp, and SRUS (4, 5). Both MPS and SRUS may share the same clinical pathological features.. The etiology of SRUS may be associated with certain lifestyles, the Sjogren syndrome (6), spinal cord injury (7), pregnancy (8), enema use or insertion of suppositories (9), and living habits such as the use of bidets (10), staying in the bathroom for a ...
The superior mesenteric artery gives off several named branches (Figure 39.1). They include the inferior pancreaticoduodenal artery, middle colic artery, right colic artery, ileocolic artery and intestinal arteries. The middle colic artery divides within the transverse mesocolon into a right branch and a left branch. Branches of these arteries supply the proximal two-thirds of the transverse colon. The ascending branch and descending branch of the right colic artery supply the ascending colon. Finally, the ileocolic artery, the terminal branch of the superior mesenteric artery, divides into the appendicular artery, anterior cecal artery, and posterior cecal artery. These arteries, together with the small branches to the ileum and ascending colon, supply the terminal portion of the ileum, cecum, vermiform appendix, and proximal part of the ascending colon.. Links and References: ...
Cystic fibrosis (CF) is a genetic disease that causes build-up of thick, sticky mucus in the lungs, pancreas and other organs. As most patients with CF experience pancreatic insufficiency and some patients have CF-related liver disease, constipation, failure to thrive, abdominal pain, and distal intestinal obstruction syndrome, they require multidisciplinary care.. To help these patients acheive the best possible outcomes, Mary Abigail Garcia, M.D., (gastroenterologist) and the CF pulmonary care team developed the Cystic Fibrosis/Gastroenterology Clinic, which combines the care provided by the Cystic Fibrosis Center and our Gastroenterology division. The Cystic Fibrosis Center is a CF Foundation-accredited center, which sees children from southern California, Arizona and Mexico.. Along with gastroenterology and CF pulmonary specialists, the Cystic Fibrosis/Gastroenterology Clinic includes nutrition, social work and nursing.. The clinic is held every 3rd Thursday morning of the month. For more ...
RPH is a type of internal hernia and is frequently associated with intestinal malrotation. Although RPH is relatively rare compared with left paraduodenal hernia, it causes high mortality as high as 50%. RPH occurs in the fossa of Waldeyer, which is typically located inferior to the third portion of the duodenum and behind the small bowel mesenteric root. During the 6th-10th week of embryonic period, midgut normally rotates 270° counterclockwise manner. Then, the prearterial jejunum lies in the left upper quadrant and the postarterial jejunum is located in the right lower quadrant. The fossa of Waldeyer is thought to result from incomplete rotation of the prearterial jejunum, and subsequent failure of fusion between the mesentery and duodenal third portion [1].. CT is the standard of reference for the diagnosis of internal hernia and its complications. In cases of internal hernia into a fossa in the retroperitoneum, the bowel loop usually appears as a pseudo-encapsulated sac-like structure on ...
Pain in the right lower quadrant may be diffuse, as in early appendicitis, or crampy and nonradiating, as in ectopic pregnancy. Colon obstruction secondary to colon cancer, diverticulitis, and ureterolithiasis are common causes of pain in this area. Yersinia enterocolitica and Campylobacter sp., may mimic appendicitis and cause right lower quadrant pain, anorexia, low grade fever, and vomiting preceding the onset of diarrhea leading to a syndrome of mesenteric adenitis (lymph node enlargement) and terminal ileitis. The classic presentation of Crohns disease is that of colicky right lower quadrant pain and diarrhea. Low-grade fever and weight loss are frequently present as well. High fever indicates a possible infectious complication (ie, abscess). Hematochezia occurs in a minority of patients, most often in those with colonic involvement ...
TY - JOUR. T1 - F-18-FDG-PET/CT imaging of small cell carcinoma of the colon. AU - Jones, Katie. AU - Subramaniam, Rathan M.. AU - Durnick, David K.. AU - Peller, Patrick J.. PY - 2008/9/1. Y1 - 2008/9/1. N2 - Small cell carcinoma of the colon is a rare entity, comprising only 1.5% of all colon cancers. It is an aggressive neoplasm with rapid local progression and early metastasis. We present a case report of F-18 FDG PET/CT features of small cell carcinoma arising in the ascending colon of an 86-year-old woman who presented with anemia and melena. FDG PET/CT demonstrated a small, intense focus of FDG hypermetabolism in the cecum. Extrapulmonary small cell carcinoma, described in the salivary glands, pharynx, esophagus, stomach, small bowel, colon, rectum, gallbladder, uterus, kidney, and skin, has a poor prognosis when involving the gastrointestinal tract.. AB - Small cell carcinoma of the colon is a rare entity, comprising only 1.5% of all colon cancers. It is an aggressive neoplasm with rapid ...
Herein, we report a model for how BRAF mutations, in contrast to KRAS mutations, specifically associate with and induce, in mouse colon organoids without a microenvironment, the phenotype of human sporadic right-sided colon adenocarcinomas (COAD). The human BRAF mutant COAD are particularly distinguished by having an increased incidence of promoter CpG island methylation, termed CpG island methylator phenotype (CIMP)-High. This latter phenotype contrasts with the majority of the COAD which are classified in the CIMP-low to intermediate groups and have mostly KRAS mutations. To understand how these mutations influence tumor evolution and the methylation landscape, we modeled the early carcinogenesis of colorectal cancer by inducing BRAFV600E and KRASG12D mutations individually in 3D organoids prepared from mouse proximal colon. The induction of BRAFV600E mutation, but not KRASG12D mutation, showed various features of progressive transformation. In vitro induction of BRAFV600E drove the organoids ...
This medical exhibit pictures an anterior (front) view of the normal anatomy of the large and small intestines. Labels are provided for the duodenum, ascending colon, terminal ileum, cecum, transverse colon, descending colon, sigmoid colon and rectum. This illustration also shows the liver and stomach.
A colon lipoma is a remarkably rare tumor. In most cases, the tumors are asymptomatic and small in size, need to be differentiated from malignant tumors, and do not need any special treatment. Selection of the right surgical strategy depends on the status of bowel, as well as the size and the location of tumor. We encountered two patients with giant submucosal lipomas that had induced intussusceptions: one with a lipoma in the transverse colon and the other with a lipoma in the ascending colon. The diagnoses were made by using histological examinations ...
TY - JOUR. T1 - Safety and efficacy of two reduced dosing regimens of sodium phosphate tablets for preparation prior to colonoscopy. AU - Rex, Douglas. AU - Chasen, R.. AU - Pochapin, M. B.. PY - 2002. Y1 - 2002. N2 - Objectives: To evaluate the safety and efficacy of two reduced dosing regimens of sodium phosphate tablets (Visicol, InKine Pharmaceutical Co. Inc., Blue Bell, PA, USA) for colon cleansing prior to colonoscopy. Methods: In a randomized, multicentre, endoscopist-blinded clinical study, adults undergoing colonoscopy received either 28 tablets (42 g) or 32 tablets (48 g) of sodium phosphate for colon cleansing. The endoscopist used a validated four-point scale to rate the overall quality of colon cleansing as well as cleansing in the ascending colon. Adverse events were collected and evaluated. Results: The quality of overall colon cleansing was excellent or good in 84% or more of both groups, with no significant difference between the two doses. No patient had a preparation rated ...
Endoscopic features of melanosis coli. The ascending colon (a) and descending colon (b) of patient no. 8, and the transverse colon of patient no. 13 before (c)
Megacolon is an abnormal dilatation of the colon (a part of the large intestines) that is not caused by mechanical obstruction. The dilatation is often accompanied by a paralysis of the peristaltic movements of the bowel, resulting in chronic constipation. In more extreme cases, the feces consolidate into hard masses inside the colon, called fecalomas (literally, fecal tumor), which require surgery to be removed.A human colon is considered abnormally enlarged if it has a diameter greater than 12 cm in the cecum, greater than 6.5 cm in the rectosigmoid region and greater than 8 cm for the ascending colon A megacolon can be either acute or chronic. It can also be classified according to etiology Etiology 1.1 Aganglionic megacolon 1.2 Toxic megacolon 1.3 Megacolon in Chagas diseaseHas your child been evaluated for Hirschsprungs disease ...
by : Fereshteh Salimi Department of General & Vascular Surgery Azar of 1392 e-mail: [email protected] Surgical Anatomy  The retroperitoneum is defined as the space between the posterior envelopment of the peritoneum and the posterior body wall . It is bounded superiorly by the diaphragm , posteriorly by the spinal column and iliopsoas muscle and inferiorly by the levator ani muscles. The anterior border is quite convoluted , extending into the spaces in between the mesenteries of the small and large intestines.  Retroperitoneal Structures          Kidneys Ureters Bladde r Pancreas Duodenum (D2 and D3) Adrenal gland Ascending colon Descending colon Rectum (upper two thirds)  Aorta Inferior vena cava Iliac vessel Seminal vesicles Vas deferens Lymphatics (cysterna chyli)  Vagina (upper most)  Ovaries  Nerves (lumbar sympathetics)      Retroperitoneal space  Retroperitoneal space are classified on an anatomic basis:  zone ...
Researchers are divided in their views regarding the most common site of the first lesion in sporadic CRC among young patients: Some of them reported that CRC was most often located in the ascending colon [7,8], whereas others noted the descending colon or rectum as the most common location, which is the same for adult patients [9]. In the present study, the descending colon or rectum was the most frequent location (16/19, 84.2%). Regarding histological subtype, adenocarcinoma is the most common type, being found in 85% of adult CRC patients, followed by mucinous adenocarcinoma (10%-15%) and signet ring cell type (1%) [10]. Unlike CRC in adults patients, however, in young patients, the most common types were mucinous adenocarcinoma (6/19, 31.5%) and signet ring cell type (2/19, 10.5%). Normally, mucinous adenocarcinoma and signet ring cell type result in poorer outcomes compared with adenocarcinoma. Poor outcomes were also found in this study as 4 of 6 patients (66%) with mucinous adenocarcinoma ...
The results of this study demonstrate the potential prognostic and predictive values of KRAS and BRAF gene mutations in patients with colorectal cancer (CRC). It has been proven that KRAS and BRAF mutations are predictive biomarkers for resistance to anti-EGFR monoclonal antibody treatment in patients with metastatic CRC (mCRC). We demonstrated the distribution of KRAS (codons 12, 13 and 61) and BRAF (codon 600) gene mutations in 50 mCRCs using direct sequencing and compared the results with clinicopathological data. KRAS and BRAF mutations were identified in 15 (30%) and 1 (2%) patients, respectively. We identified KRAS mutations in codon 12, 13 and 61 in 73.3% (11/15), 20% (3/15) and 6.67% (1/15) of the positive patients, respectively. The KRAS mutation frequency was significantly higher in tumors located in the ascending colon (p=0.043). Thus, we found that approximately 1/3 of the patients with mCRC had KRAS mutations and the only clinicopathological factor related to this mutation was tumor
182 patients (age range 18 to 74 y, 68% women) who had Crohn disease confined to the distal ileum, the ileocecal region, and the ascending colon verified by colonoscopy, small bowel follow-through, or barium enema within 24 months before randomization. Exclusion criteria were rectal Crohn disease, sepsis, abscess, perforation or active fistula, ileostomy, or colostomy; resection of , 100 cm of the ileum; need for immediate surgery; diabetes mellitus; active peptic ulcer disease; clinically important renal, hepatic, or cardiovascular disease or asthma; pregnancy or lactation; or allergy to glucocorticoids or mesalamine ...
A 67-year-old Caucasian male presented with persistent diarrhoea, weight loss of 15 kg in 3 months, and onychodystrophy. Family history is negative for colon carcinoma. He worked in oil trading and had extensive exposure to sulfuric acid, ammonia and gum resin. Physical examination revealed a vaguely palpable mass and tenderness in the left lower abdominal quadrant. Onycholysis of the fingernails (figure 1) and toenails, alopecia (figure 2) and hyperpigmentation of the skin were noted. CT demonstrated two circular thickenings in the sigmoid and colon ascendens. A … ...
Painful Obstruction Syndrome … is due to deficiency of Nutritive and Defensive Qi and to the space between skin and muscles being open, thus allowing Wind-Cold-Dampness to ride the deficiency. Qi becomes obstructed by the pathogenic factors, it cannot circulate, it stagnates, Qi and Blood congeal, and in time Painful Obstruction Syndrome develops.. ☯ The relative strength of the climatic pathogenic factors and the bodys Qi at any given time is crucial to the development of Painful Obstruction Syndrome.. ☯ It is only when the climatic factors are temporarily and relatively stronger than our bodys Qi, that they become pathogenic and cause Painful Obstruction Syndrome.. ☯ It is important to stress however, that the deficiency of bodys Qi necessary for the development of Painful Obstruction Syndrome is only relative, i.e. in relation to the strength of climatic pathogenic factors. It is not an absolute deficiency, otherwise that would mean that anyone who develops Painful Obstruction ...
List of causes of Right lower quadrant inflammation and Sick to your stomach and Nausea, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
List of causes of Abdomen spasm and Right lower quadrant lump, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
A 67-year-old man was admitted to hospital because of fever, productive cough and a concomitant hoarseness. A para-aortic lesion was found on chest X-ray, and bronchoscopy revealed a left vocal cord palsy. Due to rapid enlargement of the lesion, angiography was performed, which revealed a pseudoaneurysm at the descending aorta ...
Acheter En Ligne Bisacodyl Vente - Acheter Bisacodyl En Andorre Vente Bisacodyl Suisse Acheter Du Bisacodyl Sur Internet Forum, Bisacodyl En Suisse Acheter Tags: bisacodyl, dulcolax.
On the left a 48-year old man with clinical signs of diverticulitis. br, US reveals an ovoid, non-compressible, avascular fatty mass (arrowheads) while the adjacent sigmoid has a normal aspect. br, The neighboring fat shows hyperemia (arrows). br, During respiration the mass was seen to be adherent to the parietal peritoneum. br, The patients symptoms disappeared within a week without treatment.. These findings are typical for epiploic appendagitis.br, The mass represents the infarcted epiploic appendagebr, The patients symptoms disappeared within a week without treatment.br,. ...
I would like to share my medical story that started with a wrong diagnosis that led to the truth! So I was in fact very blessed by my wrong diagnosis.Several months ago I went to visit a gastroenterologist specialist as I had been suffering from intermittent constipation which was chronic when I had it, and happening with much more regularity. I could never understand the reason why as I ate a healthy diet with lots of fruits, veggies and fibre that would send normal constitutions to the bathroom several times a day. All I knew was that the food I was eating was not leaving my body and I was always uncomfortable with severe bloating. I had tried to loose some excess weight for years and never succeeded - I am about 10 lbs overweight.The specialist offered to do a colonoscopy (the very thing I had dreaded for years and had put off looking into my problem as a result of) I had accompanied my mum for a colonoscopy several years ago when I lived in the UK and they had to stop it as she was screaming ...
Diagnostic laparoscopy with planned appendectomy : an integral step in the evaluation of unexplained right lower quadrant pain ...
Eighteen gram-negative bacilli and cocci were selected from 40 isolates in naturally fermenting nipa sap from Paombong, Bulacan. When grown and screened in pasteurized nipa sap, 10 high acetic acid-yielding isolates were further selected. Based on their morphological and physiological characteristics, they were identified as Acetobacter aceti subsp. aceti, A. paradoxus subsp. paradoxus, six isolates of A. ascendens subsp. ascendens, A. lovaniensis subsp. lovaniensis and A. rancens subsp. pasteurianus ...
Mainly risking incredulity and recommending finding another surgeon by the patients friends, Ive on a couple of occasions treated small abscesses only with antibiotics. When a person comes into the office complaining of a months worth of somewhat annoying illness, and the workup shows mostly swelling in the appendixs homeland with only a small fluid collection, its seemed reasonable to take a pretty conservative approach. But in most cases, the patient is sicker than that, and the abscess is bigger, so drainage is best. Of course, Ive always leaned toward the surgical approach, because its the most definitive: especially for a large and loculated collection. You can get big drains in there, wiggle your finger around in the hole to break down the septations, and get it done all at once. Radiologists are getting better and braver at approaching intra-abdominal fluid collections, and its become the preferred approach in lots of situations. The one area that until fairly recently many of ...
Mainly risking incredulity and recommending finding another surgeon by the patients friends, Ive on a couple of occasions treated small abscesses only with antibiotics. When a person comes into the office complaining of a months worth of somewhat annoying illness, and the workup shows mostly swelling in the appendixs homeland with only a small fluid collection, its seemed reasonable to take a pretty conservative approach. But in most cases, the patient is sicker than that, and the abscess is bigger, so drainage is best. Of course, Ive always leaned toward the surgical approach, because its the most definitive: especially for a large and loculated collection. You can get big drains in there, wiggle your finger around in the hole to break down the septations, and get it done all at once. Radiologists are getting better and braver at approaching intra-abdominal fluid collections, and its become the preferred approach in lots of situations. The one area that until fairly recently many of ...
Eastern and central United States west to Texas and south to Miami-Dade County and the Monroe County mainland. For a digitized image of Elbert Littles Florida range map, visit the Exploring Florida website. This map also contains the range of T. ascendens. ...
Ratio-Bisacodyl information about active ingredients, pharmaceutical forms and doses by Ratiopharm, Ratio-Bisacodyl indications, usages and related health products lists
Colon cleansing is the process of taking poison from your body. These general tips will help you in your first colon cleansing experience.
Looking to meet the right Spiritual Singles in Colon? See your matches for FREE on eHarmony - #1 trusted Colon, NE online dating site.
Looking for online definition of gastrojejunal loop obstruction syndrome in the Medical Dictionary? gastrojejunal loop obstruction syndrome explanation free. What is gastrojejunal loop obstruction syndrome? Meaning of gastrojejunal loop obstruction syndrome medical term. What does gastrojejunal loop obstruction syndrome mean?
Abdominal Cramps & Food Intolerance & Left Lower Quadrant Pain Symptom Checker: Possible causes include Irritable Bowel Syndrome. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
TY - JOUR. T1 - Laparoscopic repair of a left-sided paraduodenal hernia. AU - Winder, Joshua S.. AU - Pauli, Eric. AU - Haluck, Randy. PY - 2016/8/1. Y1 - 2016/8/1. N2 - Introduction: Internal hernias are a rare cause of bowel obstruction, constituting 0.2-0.9 % of all cases with paraduodenal hernias (PDH) being the most common accounting for 50 % of all internal hernias with 75 % of those being left-sided [1, 2]. They are due to small bowel herniating into a peritoneum-lined sac at the fourth portion of the duodenum as the result of abnormal midgut rotation during embryonic development. Patients may present with symptoms of small bowel obstruction, though the majority are found incidentally [3]. Diagnosis is aided with computed tomography (CT) with findings of encapsulated clustering of small bowel loops in the left upper quadrant, bowel between the stomach and pancreas, crowding of mesenteric vessels, and displacement of the inferior mesenteric vein [4]. Methods: A 34-year-old male presented ...
Merkel cell carcinoma is a rare and aggressive skin malignancy that arises from primary neural cells and has a tendency for local recurrence and regional lymph node metastases. There are only a few cases in the literature reporting metastases of Merkel cell carcinoma to the gastrointestinal tract. We present a 70 year old Caucasian female with distant history of Merkel cell carcinoma who presented with iron-deficiency anemia. Colonoscopy performed later for the evaluation of anemia revealed 1 cm polyp in ascending colon which turned out to be the recurrence of Merkel cell carcinoma. Metastatic Merkel cell carcinoma to the gastrointestinal tract or any other organ should be considered in patients with a history of Merkel cell carcinoma.
Introduction: Neuroendocrine cells are widely distributed throughout the body, and neoplasms from these dispersed cells can arise at many sites. They are distinguished into two broad categories: 1) Tumors identified as small cell lung carcinomas with biology and natural history of a high-grade malignancy and characteristics of small cell undifferentiated or anaplastic appearance by light microscopy. The WHO categorizes these tumors as poorly-differentiated neuroendocrine carcinomas; 2) Well-defined neuroendocrine tumors (NETs) with variable, but most lyindolent biologic behavior and characteristic well-differentiated histologic features. The majority arise in the gastrointestinal tract and collectively they are referred as gastroenteropancreatic neuroendocrine tumors (GEP/NETs). They include carcinoid tumors, pancreatic islet cell tumors (gastrinoma, insulinoma, glucagonoma, VIPoma, somatostatinoma), paragangliomas, pheochromocytomas, and medullary thyroid carcinomas. The WHO classifies the ...
Appendicitis is the most common cause of abdominal pain requiring surgical intervention. It is usually caused by an obstruction of the appendiceal lumen due to fecaliths or lymphoid hyperplasia. Patients may experience sharp periumbilical pain that moves to the right lower quadrant, anorexia, nausea, vomiting, and low-grade fever.. There is typically exquisite right lower quadrant (RLQ) tenderness at McBurneys point, located one-third of the distance from the anterior-superior iliac spine (ASIS) to the umbilicus.. Other signs that point to the diagnosis of acute appendicitis include:. Obturator sign: Pain with passive flexion and internal rotation of the right hip.. Psoas sign: Pain with passive extension of the right hip.. Rovsings sign: Referred pain to the right lower quadrant with palpation of the left lower quadrant.. Labs often demonstrate leukocytosis , 10,000/μL. Urinalysis may also demonstrate microscopic hematuria and pyuria.. ...
Ascending Colon. *Right ovary and Fallopian tube. *Right ureter. Clinical significance[edit]. If abdominal pain or signs of ... Examples of tumors in the left lower quadrant include colon cancer and ovarian tumor. ...
The left colic vein drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its ... Ascending branch Descending branch Ronald W. Dudek; Thomas M. Louis (11 February 2014). High-YieldTM Gross Anatomy. Lippincott ...
The tumors are usually in the ascending colon. They also have a good prognostic outcome, so if a patient were diagnosed with ...
... but partly lying behind the cecum at its junction with the ascending colon; (d) a single gland, between the layers of the ... along the medial side of the ascending colon. The lymphatics of cecum and vermiform process from the front. The lymphatics of ... mostly placed in the angle between the ileum and the colon, ...
It is also separated from the colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon ... to the sigmoid colon, through the descending, transverse, and ascending sections. The cecum is an end point for the colon with ... The connection between the end of the cecum and the beginning of the ascending colon is called the cecocolic orifice. A cecal ... and connects to the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve (ICV) or ...
... the transverse colon, the descending colon, the sigmoid colon and the rectum. Sections of the colon are: The ascending colon ... Of the colon, the ascending colon, descending colon and rectum are retroperitoneal, while the cecum, appendix, transverse colon ... In ruminants, the ascending colon is known as the spiral colon. Taking into account all ages and sexes, colon cancer occurs ... ascending colon 6.6 (6.0-7.0), transverse colon 5.8 (5.0-6.5), descending/sigmoid colon 6.3 (6.0-6.8) and rectum near rectal/ ...
Shim HJ, Hong YK, Kim SJ, Choi YJ, Kang JG (2010). "Carcinosarcoma on ascending colon found by bowel perforation: a case report ... colon, uterus and ovaries. Four main hypotheses have been proposed for the cellular origins of carcinosarcoma, based largely on ...
In an isolated intestinal transplant, the colon will be detached from the small intestine. The cecum and ascending colon are ... In a multivisceral graft, the stomach, duodenum, pancreas, and/or colon may be included in the graft. Multivisceral grafts are ... with concentrations of up to 104-107 CFU/mL in the jejunoileum and 1011-1012 CFU/mL in the colon. While suppression of the ...
Ascending colon (ascending in the back wall of the abdomen). *Right colic flexure (flexed portion of the ascending and ... lower duodenum, jejunum, ileum, cecum, appendix, ascending colon, and first two-third of the transverse colon. branches of the ... These include the esophagus, pylorus of the stomach, distal duodenum, ascending colon, descending colon and anal canal. In ... last third of the transverse colon, to the upper part of the anal canal. last third of the transverse colon, descending colon, ...
Other locations include the ascending, transverse, and descending sections of the colon. Types of colostomy: Loop colostomy: ... Some common reasons are: A section of the colon has been removed, e.g. due to colon cancer requiring a total mesorectal ... People with colostomies who have ostomies of the sigmoid colon or descending colon may have the option of irrigation, which ... A portion of the colon (or large intestine) has been operated upon and needs to be 'rested' until it is healed. In this case ...
... ascending colon, and the proximal 2/3 of the transverse colon. The final branch which is important for the digestive system is ... which includes the distal 1/3 of the transverse colon, descending colon, sigmoid colon, rectum, and the anus above the ... The cecum receives chyme from the last part of the small intestine, the ileum, and connects to the ascending colon of the large ... Parasympathetic innervation to the ascending colon is supplied by the vagus nerve. Sympathetic innervation is supplied by the ...
It is also separated from the colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon ... to the sigmoid colon, through the descending, transverse, and ascending sections. The cecum is an end point for the colon with ... It receives chyme from the ileum, and connects to the ascending colon of the large intestine. It is separated from the ileum by ... The connection between the end of the cecum and the beginning of the ascending colon is called the cecocolic orifice. ...
This space is defined by: The ascending colon and caecum laterally (further right). The transverse colon superiorly. The root ... The descending colon laterally (further left). Peritoneal recesses Paracolic gutters Anatomy photo:37:14-0200 at the SUNY ... Paracolic gutters are recesses between the abdominal wall and the colon. These gutters are clinically important because they ... in the abdominal cavity between the colon and the root of the mesentery. There are two paramesenteric gutters; the left ...
... the descending colon, sigmoid colon and rectum. In zoology, the term hindgut refers also to the cecum and ascending colon. ... In mammals, it includes the distal third of the transverse colon and the splenic flexure, ...
The lateral boundary of the retroperitoneum is defined by the ascending and descending colon. The retroperitoneum can be ...
This nerve goes on to innervate the jejunum, ileum, ascending colon and the transverse colon. While the sympathetic input of ...
Inclusion of a diagram of the colon, labeling e.g. 'sigmoid colon', 'ascending colon', 'descending colon','transverse colon' ... The squatting theory is looking better and better, now that Burkitt's hunch about fiber has failed in the case of colon cancer ...
However, any bleeding within the upper gastrointestinal tract or the ascending colon can lead to melena. Melena may also be a ... Bleeds that originate from the lower gastrointestinal tract (such as the sigmoid colon and rectum) are generally associated ...
At the colon it divides into a descending branch, which anastomoses with the ileocolic, and an ascending branch, which ... These branches form arches, from the convexity of which vessels are distributed to the ascending colon. This article ... toward the middle of the ascending colon; sometimes the vessel lies at a higher level, and crosses the descending part of the ...
Ileum, cecum and ascending colon Cecum and ileum Ileo-cecal valve Ileo-cecal valve Pollard, MF; Thompson-Fawcett, MW; Stringer ... Approximately two litres of fluid enters the colon daily through the ileocecal valve. The ileocecal valve is distinctive ...
It is caused by rotational torsion of the cecum or ascending colon along its own axis. In cecal bascule, the base of the cecum ... Cecal bascule is a cause of large bowel obstruction where there is folding of the cecum anteriorly over the ascending colon. It ... folds anteriorly over the ascending colon, creating a flap-valve, obstructing emptying of the cecum. The condition can be ...
From colon 1 the ascending and transverse colon will be formed and from colon 2 the descending and sigmoid colons and the ... In tetrapods, the ileocaecal valve is always present, opening into the colon. The length of the small intestine is typically ...
... mutations are more commonly observed in cecal cancers than colorectal cancers located in any other places from ascending colon ... "Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma". Proceedings of the National Academy of ...
It receives faecal material from the ileum, and connects to the ascending colon of the large intestine. It is present in most ... In tetrapods, the ventral aorta has divided in two; one half forms the ascending aorta, while the other forms the pulmonary ... ascend, or descend without having to waste energy in swimming. The bladder is found only in the bony fishes. In the more ...
The colon may be regarded as two organs, the right side (cecum and ascending colon), a fermenter. The right side of the colon ... Water is distributed in the colon in three ways: Free water which can be absorbed from the colon. Water that is incorporated ... and sigmoid colon), affecting continence. The presence of bacteria in the colon produces an 'organ' of intense, mainly ... The fibers that are most effective in influencing sterol metabolism (e.g. pectin) are fermented in the colon. It is therefore ...
The right colic vein drains the ascending colon, and is a tributary of the superior mesenteric vein. It travels with its ...
Talk:Ascending cervical artery. *Talk:Ascending colon. *Talk:Ascending limb of loop of Henle ... Talk:Ascending branch of medial circumflex femoral artery. * ... Talk:Ascending palatine artery. *Talk:Ascending pharyngeal ...
This may include causes relating to the bladder, uterus, ascending (right) colon, fallopian tubes, ovaries, or other structures ...
Laparotomy showed multiple lesions and intestinal perforation at the ascending and first part of the transverse colon, with a ...
Several diseases can affect the ascending colon, or first part of your large intestine. If youre experiencing pain in this ... 4. Colon Cancer Colon cancer is the term people usually use to describe colorectal cancer, meaning cancer of the colon (which ... Diseases that affect the ascending colon include inflammatory bowel diseases and colon cancer. ... Crohns disease can affect any part of the digestive tract, often the ascending colon and the end of the small intestine. This ...
The ascending colon is the part of the colon located between the cecum and the transverse colon. The ascending colon is smaller ... 1: Ascending colon 2: Transverse colon 3: Descending colon 4: Sigmoid colon 5: Rectum Intestines Front view of the thoracic and ... Ascending colon Mesenteric relation of intestines. Deep dissection. Anterior view. Colon (anatomy) This article incorporates ... Interior of the cecum and the lower end of ascending colon, showing colic valve. Transverse section through the middle of the ...
... ascending colon explanation free. What is ascending colon? Meaning of ascending colon medical term. What does ascending colon ... Looking for online definition of ascending colon in the Medical Dictionary? ... Related to ascending colon: descending colon. as·cend·ing co·lon. [TA] the portion of the colon between the ileocecal orifice ... ascending colon (7 cases), descending colon (5 cases), sigmoid colon (10 cases), rectum (14 cases), transverse colon (2 cases) ...
His ultrasonography (USG) examination showed a 9.5 cm long annular mass at the cecum and the ascending colon. An abdominal ... Solitary Plasmacytoma of the Cecum and the Ascending Colon: Surgical Resection as a Treatment Modality. ... mass localized at the medial border of the cecum in close proximity to the ileocecal valve extending into the ascending colon ( ... P-extramedullaries rarely occur in the GI tract, stomach, small bowel, colon, or rectum. SP usually presents in the 5th or 6th ...
... Tahsin Dalgic,1 Erdal ... J. G. Allison, E. P. Getaz, and W. G. Staples, "Primary isolated extramedullary plasmacytoma of the colon: a case report," ... W. Makis, A. Ciarallo, M. Hickeson, and R. Lisbona, "Gastric recurrence of a primary colon plasmacytoma: staging and evaluating ... "Primary isolated extramedullary plasmacytoma of colon," World Journal of Surgical Oncology, vol. 5, article 47, 2007. View at ...
... ascending colon explanation. Define ascending colon by Websters Dictionary, WordNet Lexical Database, Dictionary of Computing ... Ascending. ascending aorta. ascending artery. -- ascending colon --. Ascending latitude. Ascending line. ascending node. ... ascending colon Noun. 1.. ascending colon - the part of the large intestine that ascends from the cecum to the transverse colon ... Ascending series. Ascending signs. Ascension. Ascension Day. Ascension of Christ. Ascension of the Lord. Ascensional. ...
Fowler on ascending colon pain: "stomach pain" can be caused by lots of things & may indeed originate outside the GI tract. ... Ascending Colon (Definition) The ascending colon is the portion of the large intestine "ascending" or going up the right side ... Right colon: The ascending colon is the portion of the large intestine "ascending" or going up the right side of the abdomen. ... A ascending colon polyp worse then anywhere else in the colon.How can I prevent more. High grade removed in may, surgically. ...
Methods: Between January 2011 and September 2013, 20 consecutive patients with advanced ascending colon cancer near the hepatic ... Conclusions: This laparoscopic method is useful and feasible for ascending colon cancer near the hepatic flexure. ... We present a laparoscopic radical lymphadenectomy procedure for advanced ascending colon cancer near the hepatic flexure. ... Laparoscopic radical lymphadenectomy with complete mesocolic excision for advanced ascending colon cancer near the hepatic ...
2015/16 ICD-10-CM D3A.022 Benign carcinoid tumor of the ascending colon ... Short description: Ben carcinoid asc colon.. *ICD-9-CM 209.53 is a billable medical code that can be used to indicate a ... Benign carcinoid tumor of the ascending colon. * ... Benign carcinoid of ascending colon. *Benign carcinoid tumor ... Benign carcinoid tumor, ascending colon. *Benign neuroendocrine tumor of ascending colon. *Benign neuroendocrine tumor, ...
Short description: ASCENDING COLON INJ-CLOS.. *ICD-9-CM 863.41 is a billable medical code that can be used to indicate a ... Injury to ascending (right) colon without open wound into cavity. * ... 2015/16 ICD-10-CM S36.500A Unspecified injury of ascending [right] colon, initial encounter ... Ascending colon contusion. *Ascending colon laceration. *Blast injury of ascending colon. *Traumatic ascending colon ...
... By ... In and #64258;ammation of the terminal ileum secondary to an embedded plastic sword with ulceration in the ascending colon. ... A single 6-mm ulcer was found in the proximal ascending colon at the embedded site. ... a plastic sword pick with the tip and blade in the terminal ileum and the hilt embedded in the proximal ascending colon. The ...
Other injury of ascending [right] colon, initial encounter. 2016 2017 2018 2019 2020 Billable/Specific Code *S36.590A is a ... Other injury of colon. 2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code Applicable To*Secondary blast injury of colon ... Injury of colon. 2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code Type 2 Excludes*injury of rectum (S36.6-) ... effects of foreign body in stomach, small intestine and colon (T18.2-T18.4) ...
Aintree - Herniation of the Caecum and Ascending Colon Through the Foramen of Winslow: A Case Report and Review. Authors: ...
Oncolex - cancer encyclopedia › About cancer in the colon/rectum › Treatment › Surgery colon › Tumor in cecum and ascending ... Surgery colonTumor in cecum and ascending Tumor in right flexure Tumor in transversumTumor in left flexure Tumor in descending ... Tumor in the cecum and ascending colon. GeneralEquipmentPreparationImplementationFollow-up ... Tumor in sigmoideumLocally advanced colon. Surgery rectumTEMLow anterior resectionRectum amputation (APE)Rectum amputation with ...
drugsupdate.com - Indias leading online platform for Doctors and health care professionals. Updates on Drugs, news, journals, 1000s of videos, national and international events, product-launches and much more...Latest drugs in India, drugs, drugs update, drugs update
Oncolex - cancer encyclopedia › Treatment › Surgery › Tumor in cecum and ascending. Tumor in the cecum and ascending colon. ... For cancer in the cecum and ascending colon a right-sided hemicolectomy and a standard resection of colon- and lymph nodes are ... Dissect in the anatomical plane dorsal to the mesocolon of the transversal and ascending colon and coecum. This is anterior to ... Step2 - Release the transverse colon from the middle to the right flexure.. *The gastrocolic ligament (the greater omentum) is ...
Download this Colon Organ Anatomy photo now. And search more of the webs best library of royalty-free stock images from iStock ... Colon organ anatomy - Stock image. .... Abdomen, Anatomy, Ascending Colon, Biomedical Illustration, Blue. ...
The ICD-10 Code C18.2 is the code used for Malignant neoplasm of ascending colon .An alternative description for this code is ...
Colon cancer is a potentially curable disease if it is caught in the early stages. This is the reason the American Cancer ... ascending or right colon, transverse colon, descending or left colon, and the sigmoid colon. The sigmoid colon is considered a ... These symptoms are explained by the anatomy of ascending colon. The ascending colon is wider than its descending counterpart, ... Ascending Colon Symptoms. Cancers in this part of the colon tend to go unnoticed for a long time. They may grow to quite large ...
Transverse colon[change , change source]. This part of the colon goes across the from the ascending colon. It goes underneath ... Ascending colon[change , change source]. This part of the colon goes from the cecum (where the small intestine ends) up the ... The colon is a part of the large intestine. It is between cecum and the rectum. The colon takes water from the feces that goes ... Sigmoid colon[change , change source]. This is the small "S" shaped part of the colon, about 40 cm in length, which goes from ...
... transverse and descending colon pieces H174 Chocolate Candy Mold (BODY PARTS). Intestines ascending, transverse and descending ... colon pieces H174 Chocolate Candy Mold, Cavities: 5, Mold Type: Pieces/MintsHeight: 1 9/16Width: 1 11/16Thickness: 1Bag Size: ... Intestines ascending, transverse and descending colon pieces H174 Chocolate Candy Mold. Our Products: Chocolate Molds > BODY ... Intestines ascending, transverse and descending colon pieces H174 Chocolate Candy Mold, Cavities: 5, Mold Type: Pieces/Mints. ...
... the first instance of a completely laparoscopically assisted resection and hernia repair on a patient with T4 ascending colon ... presented for further investigation of his iron deficiency anaemia and was diagnosed with adenocarcinoma of the ascending colon ... black arrows pointing to adherent ascending colon. c Laparoscopic view of the deep ring (white arrows) with ascending colon ( ... a Laparoscopic view of ascending colon (black arrows) herniating through the deep ring (white arrows). b Angled view within the ...
Short Description: Laceration of ascending [right] colon, sequela Long Description: Laceration of ascending [right] colon, ... Your colon, also known as the large intestine, is part of your digestive system. Its a long, hollow tube at the end of your ... Diverticulitis - inflammation or infection of pouches in the colon. *Irritable bowel syndrome - an uncomfortable condition ... Many disorders affect the colons ability to work properly. Some of these include ...
Ascending colon. The ascending colon, on the right side of the abdomen, is about 25 cm long in humans. It is the part of the ... The ascending colon is supplied by parasympathetic fibers of the vagus nerve (CN X).. Arterial supply of the ascending colon ... Descending colon. The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon ... Transverse colon. The transverse colon is the part of the colon from the hepatic flexure to the splenic flexure (the turn of ...
  • If you have a hyperplastic polyp in your left colon that measures less than 1cm, you will not need to attend a follow-up appointment. (netdoctor.co.uk)
  • Ulcerative colitis is a disease that can affect the ascending colon and is characterized by inflammation and sores, or ulcers, that line the inner wall of the large intestine, says the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health. (livestrong.com)
  • The Mayo Clinic describes diverticulitis as an inflammation of one or more of a person's gut diverticula - small pouches of the inner lining of the colon that push through the colon's muscular outer wall. (livestrong.com)
  • Inflammation and ulceration of the innermost lining of the colon. (studystack.com)
  • The image at left indicates heat along the ascending colon raising the index of suspicion for irritation/inflammation. (thermogramcenter.com)
  • It receives waste from the colon and stores it until it passes out of the body through the anus. (cancer.ca)
  • Such chronic irritation of the lining of the colon can cause ulcers to bleed or ooze pus. (livestrong.com)
  • Characteristic findings include a palpable medial displacement of the spleen and the absence of the pelvic flexure of the colon from its usual site in front of the pelvis. (thefreedictionary.com)