Colon ascending. Medical search

Tumors or cancer of the COLON.

The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.

A segment of the COLON between the RECTUM and the descending colon.

The segment of LARGE INTESTINE between the CECUM and the TRANSVERSE COLON. It passes cephalad from the cecum to the caudal surface of the right lobe of the LIVER where it bends sharply to the left, forming the right colic flexure.

The segment of LARGE INTESTINE between ASCENDING COLON and DESCENDING COLON. It passes from the RIGHT COLIC FLEXURE across the ABDOMEN, then turns sharply at the left colonic flexure into the descending colon.

Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS.

A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.

A pouch or sac opening from the COLON.

Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.

Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).

A malignant epithelial tumor with a glandular organization.

Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.

Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

A cell line derived from cultured tumor cells.

Hydrazines substituted with two methyl groups in any position.

Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)

Endoscopic examination, therapy or surgery of the luminal surface of the colon.

Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.

A benign epithelial tumor with a glandular organization.

Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.

Tumors or cancer of the SIGMOID COLON.

Tumors or cancer of the RECTUM.

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

The motor activity of the GASTROINTESTINAL TRACT.

The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.

The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.

Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.

One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.

Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.

Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)

Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.

Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.

Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.

A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.

A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

All of the processes involved in increasing CELL NUMBER including CELL DIVISION.

A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)

The surgical construction of an opening between the colon and the surface of the body.

Substances that inhibit or prevent the proliferation of NEOPLASMS.

Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.

Tumors or cancer of the CECUM.

Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.

Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).

The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.

Experimental transplantation of neoplasms in laboratory animals for research purposes.

The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.

A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.

A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.

High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.

The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.

A reagent that is used to neutralize peptide terminal amino groups.

A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.

Agents that are used to stimulate evacuation of the bowels.

Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.

The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.

Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Transplantation between animals of different species.

Tumors or cancer of the INTESTINES.

An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.

Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.

The relationship between the dose of an administered drug and the response of the organism to the drug.

The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.

Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.

A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.

Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.

Regular course of eating and drinking adopted by a person or animal.

A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.

New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Elements of limited time intervals, contributing to particular results or situations.

The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.

A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Hydrazines substituted by one or more methyl groups in any position.

Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.

Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

Ability of neoplasms to infiltrate and actively destroy surrounding tissue.

Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)

A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.

Opening or penetration through the wall of the INTESTINES.

A plastic operation on the esophagus. (Dorland, 28th ed)

Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.

A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).

Dilatation of the COLON, often to alarming dimensions. There are various types of megacolon including congenital megacolon in HIRSCHSPRUNG DISEASE, idiopathic megacolon in CONSTIPATION, and TOXIC MEGACOLON.

Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.

The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.

One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)

DNA present in neoplastic tissue.

In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.

A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

Tumors or cancer of the LIVER.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

Uptake of substances through the lining of the INTESTINES.

Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.

The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.

Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.

Endoscopic examination, therapy or surgery of the sigmoid flexure.

The contents included in all or any segment of the GASTROINTESTINAL TRACT.

Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.

The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

Short-chain fatty acids of up to six carbon atoms in length. They are the major end products of microbial fermentation in the ruminant digestive tract and have also been implicated in the causation of neurological diseases in humans.

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.

A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.

Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.

Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.

Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.

Antibodies produced by a single clone of cells.

The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum.

Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.

Established cell cultures that have the potential to propagate indefinitely.

An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)

A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.

A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.

A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.

Antimetabolites that are useful in cancer chemotherapy.

Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.

Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.

An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.

The normal process of elimination of fecal material from the RECTUM.

Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.

Specially designed endoscopes for visualizing the interior surface of the colon.

In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

RNA present in neoplastic tissue.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

Organic compounds which contain platinum as an integral part of the molecule.

An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.

The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.

Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.

The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.

Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.

Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.

Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.

DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.

Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.

A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.

Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.

Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.

The action of a drug in promoting or enhancing the effectiveness of another drug.

An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.

Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.

Preparations of Cassia senna and C. angustifolia (see SENNA PLANT). They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.

Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.

A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)

A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.

A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.

An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.

The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).

A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.

Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.

The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)

A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).

A subcategory of mucins that contain SIALIC ACID.

Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.

Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.

A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.

A rod-shaped, gram-positive, non-acid-fast, non-spore-forming, non-motile bacterium that is a genus of the family Bifidobacteriaceae, order Bifidobacteriales, class ACTINOBACTERIA. It inhabits the intestines and feces of humans as well as the human vagina.

Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.

A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.

Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.

An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)

Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.

Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.

The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.

The combination of two or more different factors in the production of cancer.

Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.

Tumors or cancer of the LUNG.

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

Distinguishing right from left colon by the pattern of gene expression. (1/37)

Distinct epidemiological and clinicopathological characteristics of colorectal carcinomas (CRCs) based on their anatomical location suggest different risk factors and pathways of transformation associated with proximal and distal colon carcinogenesis. These differences may reflect distinct biological characteristics of proximal and distal colonic mucosa, acquired in embryonic or postnatal development, that determine a differential response to uniformly distributed environmental factors. Alternatively, the differences in the epidemiology of proximal and distal CRCs could result from the presence of different procarcinogenic factors in the ascending versus descending colon, acting on cells with either similar or distinct biological characteristics. We applied cDNA microarray technology to explore the possibility that mucosal epithelium from adult proximal and distal colon can be distinguished by their pattern of gene expression. In addition, gene expression was studied in fetal (17-24 weeks gestation) proximal and distal colon. More than 1000 genes were expressed differentially in adult ascending versus descending colon, with 165 genes showing >2-fold and 49 genes showing >3-fold differences in expression. With almost complete concordance, biopsies of adult colonic epithelium can be correctly classified as proximal or distal by gene expression profile. Only 87 genes were expressed differently in ascending and descending fetal colon, indicating that, although anatomically relevant differences are already established in embryonic colon, additional changes in gene expression occur in postnatal development. (+info)

Effects of nifedipine and nickel on plateau potentials generated in submucosal interstitial cells distributed in the mouse proximal colon. (2/37)

The effects of nifedipine and nickel ions (Ni2+), known inhibitors of L- and T-type voltage-gated Ca-channels respectively, were investigated on plateau potentials recorded from submucosal interstitial cells distributed in the mouse proximal colon. Plateau potentials were generated at a frequency of about 15 times min(-1) and were formed of two components. The primary component had an initial fast rate of rise with a transient potential (rate of rise, 130 mV/s; peak amplitude, 35 mV) and was followed by a secondary plateau component with a sustained potential (amplitude, 25 mV; duration, 2.6 s). Each cell from which recordings were made was injected with neurobiotin. Subsequent morphological examination with a confocal microscope indicated successful visualization of injected cells only in the presence of 18beta-glycylrhetinic acid (an inhibitor of gap junctional connections), suggesting that these cells were dye-coupled with surrounding cells. The cells injected with neurobiotin exhibited an oval-shaped cell body with bipolar processes and were distributed in the submucosal layer, suggesting that they were submucosal interstitial cells of Cajal (ICC-SM). The plateau potentials were not altered by 0.01 microM nifedipine, but were reduced in duration by 0.1 microM nifedipine, and abolished by 1 microM nifedipine. The rate of rise of plateau potentials, but not their amplitude, was reduced by Ni2+ (> 10 microM), with no significant alteration of the membrane potential. In the presence of 100 microM Ni2+, the plateau potentials were changed to a triangular form. Thus, the plateau potentials were formed by two types of voltage-gated channel current: the initial component was produced by a Ni2+-sensitive channel current and the plateau component by a nifedipine-sensitive current. The possible involvement of two different types of voltage-gated Ca2+-channels in the generation of submucosal pacemaker potentials was discussed. (+info)

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/37)

1. Mechanisms involved in Ca(2+) sensitization of contractile elements induced by the activation of muscarinic receptors in membrane-permeabilized preparations of the rat proximal and distal colon were studied. 2. In alpha-toxin-permeabilized preparations from the rat proximal and distal colon, Ca(2+) induced a rapid phasic and subsequent tonic component. After Ca(2+)-induced contraction reached a plateau, guanosine 5'-triphosphate (GTP) and carbachol (CCh) in the presence of GTP further contracted preparations of both the proximal and distal colon (Ca(2+) sensitization). Y-27632, a rho-kinase inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization more significantly in the proximal colon than in the distal colon. 3. Y-27632 at 10 microm had no effect on Ca(2+)-induced contraction or slightly inhibited phorbol-12,13-dibutyrate-induced Ca(2+) sensitization in either proximal or distal colon. Chelerythrine, a protein kinase C inhibitor, inhibited GTP plus CCh-induced Ca(2+) sensitization in the distal colon, but not in the proximal colon. The component of Ca(2+) sensitization that persisted after the chelerythrine treatment was completely inhibited by Y-27632. 4. In beta-escin-permeabilized preparations of the proximal colon, C3 exoenzyme completely inhibited GTP plus CCh-induced Ca(2+) sensitization, but PKC(19-31) did not. In the distal colon, C3 exoenzyme abolished GTP-induced Ca(2+) sensitization. It inhibited CCh-induced sensitization by 50 % and the remaining component was inhibited by PKC(19-31). 5. These results suggest that both protein kinase C and rho pathways in parallel mediate the Ca(2+) sensitization coupled to activation of muscarinic receptors in the rat distal colon, whereas the rho pathway alone mediates this action in the proximal colon. (+info)

Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/37)

BACKGROUND: Because of their suggested link with microsatellite instability high colorectal cancers, right sided hyperplastic polyps (HPs) may differ from their distally located counterparts. This is highlighted by the recognition of a variant HP, termed sessile serrated adenoma (SSA), which predominates in the proximal colon. HPs displaying the morphological features now associated with SSAs have been shown to have altered expression of "cancer associated" markers, but no studies have investigated whether this is dependent on anatomical location of the polyps. AIMS: To evaluate morphological and functional features in right versus left sided HPs from patients without colorectal cancer with the aim of identifying distinguishing characteristics. METHODS: HPs originating in the proximal and distal colorectum were histochemically and immunohistochemically stained to evaluate a panel of markers related to proliferation and differentiation. In addition, a series of morphological features was evaluated for each polyp. RESULTS: Crypt serration, crypt dilatation, and horizontal crypt growth were more common among HPs from the right side, whereas histochemical factors including mucin changes, global methylation status, and expression of carcinoembryonic antigen were not significantly different. An age disparity was also seen between patients with right versus left sided lesions, with patients with right sided lesions being an average of more than 10 years younger than those with left sided lesions. CONCLUSIONS: These findings suggest that right and left sided HPs differ mainly in terms of growth regulation rather than cellular differentiation, implying that these lesions belong to a continuous spectrum of serrated polyps that differ quantitatively rather than qualitatively. (+info)

A rare case of ascending colon actinomycosis mimicking cancer. (5/37)

BACKGROUND: Actinomycosis is a rare inflammatory disease caused by an anaerobic bacterium that can rarely affect the large intestine. CASE PRESENTATION: We present a rare case of a cecum and ascending colon actinomycosis in a 72 years old woman, mimicking clinically a malignant inflammatory tumor of the right colon. The patient complained of right lower quadrant pain. Although our first thought was a peri-appendiceal abscess, CT scan suggested a right colon tumor. The patient underwent a right colectomy and the histological examination of the specimen revealed colon actinomycosis. CONCLUSIONS: Preoperative diagnosis in colon actinomycosis is difficult to achieve. Treatment of choice is antibiotics administration. A review of the possible pathogenesis and therapeutic modalities is also presented. (+info)

Treatment of resistant distal intestinal obstruction syndrome with a modified antegrade continence enema procedure. (6/37)

We report a case of a patient with CF who had a long history of recurrent distal intestinal obstruction syndrome. She had been treated with conventional treatment including gastrografin, n-acetyl cysteine, Klean prep and Picolax. She underwent a modified antegrade continence enema procedure. She currently irrigates her conduit every 2-3 days. She has had no further symptoms of distal intestinal obstruction syndrome. (+info)

The retroperitoneal surface in distal caecal and proximal ascending colon carcinoma: the Cinderella surgical margin? (7/37)

BACKGROUND: Mesorectal margin tumour involvement is a predictor of local recurrence in rectal carcinoma and an indication for postoperative radiotherapy in suitable patients. However, the prevalence of non-peritonealised surgical margin involvement in ascending colon carcinoma is unknown. AIMS: To test the hypothesis that retroperitoneal surgical margin (RSM) tumour involvement occurs in distal caecal and proximal ascending colon carcinoma. METHODS/RESULTS: One hundred right hemicolectomy specimens, removed for adenocarcinoma of the caecum or proximal ascending colon, were studied. During routine specimen dissection, at least one additional tissue block was taken to include the tumour and the RSM. The tumour distance from the RSM was recorded. RSM tumour involvement was present in seven cases (7%). Direct (non-nodal) RSM tumour involvement (five cases) only occurred in posterior or circumferential tumours. CONCLUSIONS: RSM tumour involvement occurs within a considerable number of distal caecal and proximal ascending colon carcinomas. The rate of RSM tumour involvement identified here is similar to a previously published local recurrence rate of 10% in caecal carcinoma, suggesting that RSM tumour involvement may be a predictor of recurrence in these tumours. Therefore, patients with distal caecal or proximal ascending colon carcinoma and RSM tumour involvement may benefit from postoperative radiotherapy. (+info)

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (8/37)

BACKGROUND: Despite the fact that the alimentary tract is part of the body's first line of defense against orally ingested xenobiotica, little is known about the distribution and expression of cytochrome P450 (CYP) enzymes in human colon. Therefore, expression and protein levels of four representative CYPs (CYP2C(8), CYP2E1, CYP3A4, and CYP3A5) were determined in human colon mucosa biopsies obtained from ascending, descending and sigmoid colon. METHODS: Expression of CYP2C, CYP2E1, CYP3A4, and CYP3A5 mRNA in colon mucosa was determined by RT-PCR. Protein concentration of CYPs was determined using Western blot methods. RESULTS: Extensive interindividual variability was found for the expression of most of the genes. However, expression of CYP2C mRNA levels were significantly higher in the ascending colon than in the sigmoid colon. In contrast, mRNA levels of CYP2E1 and CYP3A5 were significantly lower in the ascending colon in comparison to the descending and sigmoid colon. In sigmoid colon protein levels of CYP2C8 were significantly higher by ~73% than in the descending colon. In contrast, protein concentration of CYP2E1 was significantly lower by ~81% in the sigmoid colon in comparison to the descending colon. CONCLUSION: The current data suggest that the expression of CYP2C, CYP2E1, and CYP3A5 varies in different parts of the colon. (+info)

... the ascending colon is the part of the colon located between the cecum and the transverse colon. The ascending colon is smaller ... with ascending colon (at left) measuring on average 6.6 cm (range 6.0-7.0 cm). 1: Ascending colon 2: Transverse colon 3: ... The term right colon is hypernymous to ascending colon in precise use; many casual mentions of the right colon chiefly concern ... Ascending colon Mesenteric relation of intestines. Deep dissection. Anterior view. Descending colon This article incorporates ...

https://en.wikipedia.org/wiki/Ascending_colon

The right colic artery supplies the ascending colon. In a right hemicolectomy to remove the caecum and the ascending colon, the ... It supplies the ascending colon. It may be removed in a right hemicolectomy. The right colic artery is a branch of the superior ... At the colon, it divides into a descending branch and an ascending branch. The descending branch anastomoses with the ileocolic ... These branches form arches, from the convexity of which vessels are distributed to the ascending colon. The right colic artery ...

https://en.wikipedia.org/wiki/Right_colic_artery

Alex Colon (2013-02-24). "Hands On With the Huawei Ascend P2". pcmag.com. Retrieved 2013-02-24. "China's Huawei reveals ' ... "Huawei Ascend P2 brings 'world's fastest' 4G at 150Mbps". Retrieved 22 July 2013. "Huawei Ascend P2 UK release date revealed, ... The Huawei Ascend P2 is a smartphone manufactured by Huawei. It was released in 2013. It is claimed to be the world's fastest ... The Ascend P2 ships with Android 4.1 with Huawei's Emotion UI. "MHL adapter for HTC One? - Post #32". forum.xda-developers.com ...

https://en.wikipedia.org/wiki/Huawei_Ascend_P2

The left colic vein drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its ... Ascending branch Descending branch Ronald W. Dudek; Thomas M. Louis (11 February 2014). High-YieldTM Gross Anatomy. Lippincott ...

https://en.wikipedia.org/wiki/Left_colic_vein

The tumors are usually in the ascending colon. They also have a good prognostic outcome. Clinically distinct phenotypes of CIMP ...

https://en.wikipedia.org/wiki/CpG_island_hypermethylation

... but partly lying behind the cecum at its junction with the ascending colon; (d) a single gland, between the layers of the ... along the medial side of the ascending colon. The mesocolic lymph nodes are numerous, and lie between the layers of the ... and the ascending and transverse parts of the colon; lymph drains into the preaortic glands. The lymphatics of cecum and ... mostly placed in the angle between the ileum and the colon, ... in close relation to the transverse colon; they are best ...

https://en.wikipedia.org/wiki/Superior_mesenteric_lymph_nodes

It is also separated from the colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon ... to the sigmoid colon, through the descending, transverse, and ascending sections. The cecum is an end point for the colon with ... It receives chyme from the ileum, and connects to the ascending colon of the large intestine. It is separated from the ileum by ... The connection between the end of the cecum and the beginning of the ascending colon is called the cecocolic orifice. A cecal ...

https://en.wikipedia.org/wiki/Cecum

The four sections of the colon are: the ascending colon, transverse colon, descending colon, and sigmoid colon. These sections ... Of the colon, the ascending colon, descending colon and rectum are retroperitoneal, while the cecum, appendix, transverse colon ... In ruminants, the ascending colon is known as the spiral colon. Taking into account all ages and sexes, colon cancer occurs ... The ascending colon receives fecal material as a liquid. The muscles of the colon then move the watery waste material forward ...

https://en.wikipedia.org/wiki/Large_intestine

Shim HJ, Hong YK, Kim SJ, Choi YJ, Kang JG (2010). "Carcinosarcoma on ascending colon found by bowel perforation: a case report ... colon, uterus and ovaries. Four main hypotheses have been proposed for the cellular origins of carcinosarcoma, based largely on ...

https://en.wikipedia.org/wiki/Carcinosarcoma

Other locations include the ascending, transverse, and descending sections of the colon. Pouches and the stick-on appliances to ... Some common reasons are: A part of the colon has been removed, e.g. due to colon cancer requiring a total mesorectal excision, ... People with colostomies who have ostomies of the sigmoid colon or descending colon may have the option of irrigation, which ... A part of the colon has been operated upon and needs to be 'rested' until it is healed. In this case, the colostomy is often ...

https://en.wikipedia.org/wiki/Colostomy

... ascending colon, and the proximal 2/3 of the transverse colon. The final branch which is important for the digestive system is ... which includes the distal 1/3 of the transverse colon, descending colon, sigmoid colon, rectum, and the anus above the ... The cecum receives chyme from the last part of the small intestine, the ileum, and connects to the ascending colon of the large ... Parasympathetic innervation to the ascending colon is supplied by the vagus nerve. Sympathetic innervation is supplied by the ...

https://en.wikipedia.org/wiki/Human_digestive_system

This space is defined by: The ascending colon and caecum laterally (further right). The transverse colon superiorly. The root ... The descending colon laterally (further left). Peritoneal recesses Paracolic gutters Anatomy photo:37:14-0200 at the SUNY ... Paracolic gutters are recesses between the abdominal wall and the colon. These gutters are clinically important because they ... spaces in the abdominal cavity between the colon and the root of the mesentery. There are two paramesenteric gutters; the left ...

https://en.wikipedia.org/wiki/Paramesenteric_gutters

... sigmoid colon and up to the ano-rectal junction. In zoology, the term hindgut refers also to the cecum and ascending colon. ... In mammals, it includes the distal one third of the transverse colon and the splenic flexure, the descending colon, ...

https://en.wikipedia.org/wiki/Hindgut

The lateral boundary of the retroperitoneum is defined by the ascending and descending colon. The retroperitoneum can be ...

https://en.wikipedia.org/wiki/Retroperitonium

The comma, semicolon, colon, and period are seen as steps, ascending from low to high; the semicolon thereby being an ... COLONS AND SEMI-COLONS Should be preceded by a hair space only. Spencer, Dave (15 February 2011). "Review". glyphic.design ( ... The Period is a pause in quantity or duration double of the Colon; the Colon is double of the Semicolon; and the Semicolon is ... Colon Comma Period (punctuation) Note: this is February 1495 by the Venetian calendar, or MVD in Roman numerals. Several texts ...

https://en.wikipedia.org/wiki/Semicolon

The mesentery associated with the ascending colon and descending colon is resorbed, bringing these parts of the colon into ... the ascending colon and the initial two-thirds of the transverse colon. As the foetus grows larger, the mid-gut loop is drawn ... "the mesentery of the ascending colon fuses with the parietal peritoneum on this wall and disappears; consequently the ascending ... This process brings the ascending colon to lie vertically in the lateral right portion of the abdominal cavity apposed to the ...

https://en.wikipedia.org/wiki/Mesentery

However, any bleeding within the upper gastrointestinal tract or the ascending colon can lead to melena. Melena may also be a ... such as the sigmoid colon and rectum) are generally associated with the passage of bright red blood, or hematochezia, ...

https://en.wikipedia.org/wiki/Melena

Ileum, cecum and ascending colon Cecum and ileum Ileo-cecal valve Ileo-cecal valve Pollard, MF; Thompson-Fawcett, MW; Stringer ... Approximately two liters of fluid enters the colon daily through the ileocecal valve. The histology of the ileocecal valve ...

https://en.wikipedia.org/wiki/Ileocecal_valve

It is caused by rotational torsion of the cecum or ascending colon along its own axis. In cecal bascule, the base of the cecum ... Cecal bascule is a cause of large bowel obstruction where there is folding of the cecum anteriorly over the ascending colon. It ... folds anteriorly over the ascending colon, creating a flap-valve, obstructing emptying of the cecum. The condition can be ...

https://en.wikipedia.org/wiki/Cecal_bascule

It receives faecal material from the ileum, and connects to the ascending colon of the large intestine. It is present in most ... In tetrapods, the ventral aorta is divided in two; one half forms the ascending aorta, while the other forms the pulmonary ... ascend, or descend without having to waste energy in swimming. The bladder is found only in the bony fishes. In the more ...

https://en.wikipedia.org/wiki/Fish_anatomy

This nerve goes on to innervate the jejunum, the ileum, the ascending colon and the transverse colon. While the sympathetic ...

https://en.wikipedia.org/wiki/Superior_mesenteric_ganglion

The right colic vein drains the ascending colon, and is a tributary of the superior mesenteric vein. It travels with its ...

https://en.wikipedia.org/wiki/Right_colic_vein

... ascending) part of the duodenum, 31 patients; jejunum, 44 patients; ileum, 17 patients; cecum, 13 patients; colon and rectum, ...

https://en.wikipedia.org/wiki/Duodenal-type_follicular_lymphoma

In an isolated intestinal transplant, the colon will be detached from the small intestine. The cecum and ascending colon are ... In a multivisceral graft, the stomach, duodenum, pancreas, and/or colon may be included in the graft. Multivisceral grafts are ... with concentrations of up to 104-107 CFU/mL in the jejunoileum and 1011-1012 CFU/mL in the colon. While suppression of the ...

https://en.wikipedia.org/wiki/Intestine_transplantation

The ileum and ascending colon can also be used to create a pouch accessible for catheterization (Indiana pouch). Urethral ...

https://en.wikipedia.org/wiki/Neurogenic_bladder_dysfunction

This may include causes relating to the bladder, uterus, ascending (right) colon, fallopian tubes, ovaries, or other structures ...

https://en.wikipedia.org/wiki/Rovsing's_sign

... ascending to First Division. The institution's most important accomplishment is the championship of First Division Argentine ... In 1965 Colon won the Primera B title. The first game played by Colón in Primera was v Chacarita Juniors on 6 May 1966. After ... Colon did not qualify for the Nacional until 1968, although the squad did then managed a 6th-place finish. Colón finished 2nd ... Club Atlético Colón de Santa Fe (Spanish pronunciation: [ˈkluβ aˈtletiko koˈlon]), commonly referred to as Colón de Santa Fe [ ...

https://en.wikipedia.org/wiki/Club_Atlético_Colón

The central right region is called the right lumbar region and contains the ascending colon and the right edge of the small ... The lower right square is the right iliac region and contains the right pelvic bones and the ascending colon. The lower left ... The right lower quadrant (RLQ) includes the right half of the small intestines, ascending colon, right pelvic bone and upper ... The left upper quadrant (LUQ) includes the lower left ribs, stomach, spleen, and upper left area of the transverse colon. ...

https://en.wikipedia.org/wiki/Anatomical_terminology

Lesions are often multiple, and frequently involve the cecum or ascending colon, although they can occur at other places. ... It is a degenerative lesion, acquired, probably resulting from chronic and intermittent contraction of the colon that is ... Jovino, R.; Pontecorvo, C.; Pesce, G.; Jovino, P. (Feb 1989). "[Angiodysplasia of the colon]". Minerva Chir. 44 (4): 633-5. ... Angiodysplasia of the colon]". Minerva Chir. 44 (9): 1389-93. PMID 2668797. Obscure gastrointestinal bleeding and calcific ...

https://en.wikipedia.org/wiki/Angiodysplasia

In the caecum, the ascending colon, the descending colon and sigmoid colon the positions of these bands are fixed. The taenia ... The taenia mesocolica is present on the posteromedial surface of caecum, ascending, descending and sigmoid colon, but is placed ... The taenia omentalis is situated posterolaterally in caecum, ascending, descending and sigmoid colon, but is situated on the ... of smooth muscle on the outside of the ascending, transverse, descending and sigmoid colons. They are visible and can be seen ...

https://en.wikipedia.org/wiki/Taenia_coli

Diverticulitis is a common cause of abdominal pain resulting from outpouchings that particularly affects the colon. Functional ... such as ascending cholangitis.: 977-978, 963-968 Disease of the biliary tree may cause pain in the upper right abdomen, ...

https://en.wikipedia.org/wiki/Gastrointestinal_disease

Basilio entered the Estadio Olímpico Universitario and ran a lap around the track before ascending the ramp up to the cauldron ... finally being carried into the port by Cristóbal Colón Carbajal, a direct descendant of Columbus. The crossing of the Atlantic ...

https://en.wikipedia.org/wiki/1968_Summer_Olympics_torch_relay

... ascending colon, 84% when inserted into the distal colon. Upon resolution of diarrhea, C. diff toxin tests were found negative ... diff affected site in the colon and the sample may be degraded before reaching the colon-accounting for its lower resolution ... Upper endoscopy and nasogastric tubes are commonly used to avoid performing an endoscopy through an inflamed colon where there ... and irritable colon. There is little known about the possible long-term risk of transmitting an autoimmune disease. Protocols ...

https://en.wikipedia.org/wiki/Bacteriotherapy

While ascending from the Calshot Air Station, the Short S.128 they are flying passes over motorboat on Southampton Water where ... 2 May A U.S. Army seaplane en route on afternoon flight from Balboa, Panama to France Field, near present-day Colón, Panama, ... "Lowe helped avoid panic after the First Battle of Manassas by ascending to a height of 3 miles and reporting that no ... Theodore E. Martin-Leake, 28, and William T. M'Clintock Caulfield, 27, of the British Army ascend at 1630 hrs. from the ...

https://en.wikipedia.org/wiki/List_of_accidents_and_incidents_involving_military_aircraft_before_1925

Antiguo Cuscatlán Chiltiupán Ciudad Arce Colón Comasagua Huizúcar Jayaque Jicalapa La Libertad Nuevo Cuscatlán Opico ... It was ascended to the category of departmental head on January 28, 1865. The parks "Daniel Hernandez", with the bust in marble ...

https://en.wikipedia.org/wiki/La_Libertad_Department_(El_Salvador)

... the ascending, transverse and descending colons, the sigmoid colon and the rectum. Other vital organs inside the abdomen ... It indicates roughly the transverse colon, the lower ends of the kidneys, and the upper limit of the transverse (3rd) part of ... The left mid-Poupart line corresponds in its upper three-quarters to the inner edge of the descending colon. The right ... The abdominal cavity contains most organs of the digestive system, including the stomach, the small intestine, and the colon ...

https://en.wikipedia.org/wiki/Abdomen

On July 6, 1973, Rafael Hernández Colón activated the PRNG in response to a strike being declared in the Autoridad de Fuentes ... Juan Cordero took office on October 1, 1958, and was ascended to the rank of Brigadier General. On February 21, 1960, ... In 1975 the facility was renamed from Camp Salinas to Camp Santiago in honor of Specialist Four Héctor Santiago-Colón, who ... On November 28, 1974, Hernández Colón activated the national guard again, this time in response to a strike being declared in ...

https://en.wikipedia.org/wiki/Puerto_Rico_National_Guard

... passing in front of the small intestines and doubles back to ascend to the transverse colon before reaching to the posterior ... and ascending as far as the transverse colon, where they separate and enclose that part of the intestine. These individual ... ligament-extends to the underside of the left dome of the diaphragm Gastrocolic ligament-extends to the transverse colon ( ...

https://en.wikipedia.org/wiki/Greater_omentum

The gravid female pinworms settle in the ileum, caecum (i.e., beginning of the large intestine), appendix and ascending colon, ... The gravid female pinworms migrate through the colon towards the rectum at a rate of 12 to 14 cm per hour. They emerge from the ... and migrate through the small intestine towards the colon. During this migration, they moult twice and become adults. Females ...

https://en.wikipedia.org/wiki/Pinworm_(parasite)

The U.S. Navy gunboat Machias was dispatched to Colon on the isthmus of Panama, at that time still part of Colombia, in order ... No other attempt to ascend Pikes Peak until nearly 12 years later. Born: Robert Francis, American poet, in Upland, Pennsylvania ...

https://en.wikipedia.org/wiki/August_1901

The Venezuelan composer Eric Colon wrote an opera called El Caballero de Ledesma that premiered on 5 May 1979, in a sold-out ... used by the native Indians to ascend the mountain. From there down the mountain into the valley of St. Francis, a road so rocky ...

https://en.wikipedia.org/wiki/Preston–Somers_expedition

... and an upper part of the ascending colon. In a right hemicolectomy to remove the caecum and the ascending colon, the right ... It is a branch of the superior mesenteric artery that mostly supplies the transverse colon. Parts of it may be removed in ... marginal artery of the colon This article incorporates text in the public domain from page 609 of the 20th edition of Gray's ... The arches formed are about two fingers' breadth from the transverse colon, to which they distribute branches. The middle colic ...

https://en.wikipedia.org/wiki/Middle_colic_artery

The Colón family has established its presence in WWE. The first member was Carlos Colón Sr., who first worked for the promotion ... resulting in fines ascending to several thousands of dollars. In 2011, the Commission was revived with Miguel Laureano, son of ... After blaming Colón for losing the championship, he defeated all of the midcard face (fan favorite) wrestlers. Eventually Colón ... The last of the Colón-Abdullah matches took place in 1997, when Colón won a "loser leaves Puerto Rico" contest. This banishment ...

https://en.wikipedia.org/wiki/Professional_wrestling_in_Puerto_Rico

Specifically, the LGR5+ve stem cells contribute into the formation of the thick ascending limb of Henle's loop and the distal ... Similarly, LGR5 expression in the colon resembles faithfully that of the small intestine. The normal liver has very low ... "Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors". Cancer ...

https://en.wikipedia.org/wiki/LGR5

Shortly after his promotion, Chong was appointed as the new Chief Judge of Sabah and Sarawak in 1995, thus ascending to the ... Chong passed away on 23 January 2006 at his home in Kuching having suffered from colon cancer for the previous 18 months. " ...

https://en.wikipedia.org/wiki/Chong_Siew_Fai

... and the ascending and transverse colon. They directly innervate the ovarian theca and secondary interstitial cells and exert an ...

https://en.wikipedia.org/wiki/Celiac_ganglia

He also sighted the Amazon River and ascended to a point about fifty miles from the sea. He called it the "Río Santa María de ... "Nueva lista documentada de los tripulantes de Colón en 1492". Izquierdo Labrado, Julio (1987) Palos de la Frontera en el ...

https://en.wikipedia.org/wiki/Vicente_Yáñez_Pinzón

... infantile onset ascending; 607225; ALS2 Spastic paraplegia 10; 604187; KIF5A Spastic paraplegia 15; 270700; ZFYVE26 Spastic ... SHH Colon cancer, somatic; 114500; PTPRJ Colorblindness, deutan; 303800; OPN1MW Colorblindness, tritan; 190900; OPN1SW ...

https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes

... at which he presented a surgical specimen of an inflammatory tumour of the terminal ileum with a fistula to the ascending colon ...

https://en.wikipedia.org/wiki/Antoni_Leśniowski

I have been thinking of how far a soul can ascend if it lets itself be possessed entirely by God." Commenting on this passage, ... and said that he and his cohorts drove the assassin to the chapel and paid him 1,000 Salvadoran colóns after the event. In ...

https://en.wikipedia.org/wiki/Óscar_Romero

He began to study in the Cristobal Colon and Tarqui Colleges and he incorporated as Doctor in Jurisprudence in the Guayaquil ... and in the 90s he ascend to the Third Criminal Court. In 2002 he was called by the Ecuadorian Supreme Court of Justice to ...

https://en.wikipedia.org/wiki/Miguel_Félix_López

He ascended the top turnbuckle in an attempt to dive on his opponent, who countered with a dropkick. The challenger ascended ... The Colóns, and Rhodes and DiBiase (collectively known as The Legacy). Two weeks following the event on the July 6 episode of ... Hardy escaped with some offense before ascending the top turnbuckle and attempting with his finishing maneuver, the Swanton ...

https://en.wikipedia.org/wiki/Night_of_Champions_(2009)

... colon MeSH A03.556.124.526.356.333 - ascending colon MeSH A03.556.124.526.356.500 - descending colon MeSH A03.556.124.526. ... colon MeSH A03.556.249.249.356.333 - ascending colon MeSH A03.556.249.249.356.500 - descending colon MeSH A03.556.249.249. ... 356.668 - sigmoid colon MeSH A03.556.124.526.356.834 - transverse colon MeSH A03.556.124.526.767 - rectum MeSH A03.556.124.684 ... 356.668 - sigmoid colon MeSH A03.556.249.249.356.834 - transverse colon MeSH A03.556.249.249.767 - rectum MeSH A03.556.249.750 ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(A03)

He ascended to the rank of President of the American College of Legal Medicine in 2005 and was honored with the organization's ... the medical device now commonly used to screen patients for colon cancer. Dr. Cifarelli earned his reputation as one of the ...

https://en.wikipedia.org/wiki/Philip_S._Cifarelli

Let ϕ : G → H {\displaystyle \phi \colon G\to H} be a Lie group homomorphism and let ϕ ∗ {\displaystyle \phi _{*}} be its ... Gnil/1 is nilpotent, and therefore its ascending central series has all quotients abelian. This can be used to reduce some ... colon {\mathfrak {g}}\to {\mathfrak {h}},} which turns out to be a Lie algebra homomorphism (meaning that it is a linear map ...

https://en.wikipedia.org/wiki/Lie_group

Jejunum Ileum Cecum Appendix Ascending colon Hepatic flexure of colon Transverse colon (proximal two-thirds) Arterial supply to ... about two-thirds of the way through the transverse colon. During development, the human midgut undergoes a rapid phase of ...

https://en.wikipedia.org/wiki/Midgut

BioChains Total RNAs are isolated from a wide variety of documented human normal, diseased, and tumor tissues, mouse, rat, monkey, and plant tissues. Total RNA isolation is performed using proprietary techniques. Contamination by RNase, genomic DNA poly

https://www.biochain.com/products/total-rna-monkey-cynomolgus-normal-tissue-colon-ascending

How effective are second-generation colon capsule endoscopes at evaluating the severity of mucosal inflammation in patients ... Ascending colon. Transverse colon. Proximal left-sided colon. Distal left-sided colon. ... Background and Aim Colon capsule endoscopy has already been used for colon visualization and detection of polyps but its ... Colon capsule endoscopy (CCE) was first reported in 2006.[5] CCE has been applied mainly for colorectal cancer screening.[5-13] ...

https://www.medscape.com/viewarticle/807021

... it continues in a tube that goes up on the right side of your body called the ascending colon.. The job of the ascending colon ... from: wikipedia - ascending colon). The word ascending means going up.. Kid Facts - Blast from the past: Forearm Extensors ...

https://www.kid-facts.com/2014/09/ascending-colon.html

Ascending colon. Colon ascendens. The ascending colon is a vertical segment of the colon that passes upward from the cecum to ... Colon transversum. The transverse colon is a horizontal segment of the colon. It is the segment between the ascending colon and ... Descending colon. Colon descendens. The descending colon is a vertical segment of the colon that passes downward through the ... The sigmoid colon is the shortest and narrowest part of the colon. ...

https://www.visiblebody.com/learn/digestive/glossary

Hodgkin lymphoma involving ascending colon and mesenteric lymphnodes: A rare entity.. Authors: Gupta, D. Sharma, A. Dwary, A. ... Hodgkin lymphoma involving ascending colon and mesenteric lymphnodes: A rare entity. Indian Journal of Cancer. 2009 Apr-Jun; 46 ...

https://imsear.searo.who.int/handle/123456789/51232

The large bowel is also called the large intestine or colon. ... The colon is attached to the outer wall of your belly. Stool ... Ascending colectomy; Descending colectomy; Transverse colectomy; Right hemicolectomy; Left hemicolectomy; Low anterior ... The large bowel is also called the large intestine or colon.. *Removal of the entire colon and the rectum is called a ... Colon and rectum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. ...

https://medlineplus.gov/ency/article/002941.htm

T cell/histiocyte rich large B cell lymphoma of ascending colon: a rare entity. International Surgery Journal. 2020 Mar; 7(3): ... Radiological investigations (USG and CECT whole abdomen) reported an asymmetrical ill-defined growth in ascending colon and ... Surgical exploration revealed an ascending colon mass with retroperitoneal lymphadenopathy. Right hemi-colectomy with end ... T cell/histiocyte rich large B cell lymphoma of ascending colon: a rare entity. ...

https://imsear.searo.who.int/handle/123456789/212894?locale=zh_TW

Semicolon on Windows, colon otherwise. SCANDIR_SORT_ASCENDING. (int) SCANDIR_SORT_DESCENDING. (int) SCANDIR_SORT_NONE. (int) ...

https://www.php.net/manual/en/dir.constants.php

... and answers will help you understand the medical language used in the pathology report you received for your biopsy for colon ... The ascending colon, transverse colon, descending colon, and sigmoid colon are other parts of the colon after the cecum. The ... What if my report mentions the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, or rectum?. These are ... What is a polyp in the colon?. A polyp is a projection (growth) of tissue from the inner lining of the colon into the lumen ( ...

https://www.cancer.org/treatment/understanding-your-diagnosis/tests/understanding-your-pathology-report/colon-pathology/colon-polyps-sessile-or-traditional-serrated-adenomas.html

Ascending Colon 21044 Hepatic Flexure 21045 Transverse Colon 21046 Splenic Flexure 21047 Descending Colon 21048 Sigmoid Colon ... Colon and Rectum 21041-21049 Colon excluding Rectum 21041 Cecum 21042 Appendix 21043 ...

https://wonder.cdc.gov/wonder/help/cancer-v2015.html

Categories: Colon, Ascending Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 1 ...

https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Colon,+Ascending&parentid=6747&catid=42296

Food and Drug Administration has approved an at-home colon cancer test. Called Cologuard , it is the first stool-based ... https://extraproxies.com/java-string-ascending-programme/. April 15, 2021 at 08:29 , Report abuse , Reply ... New at-home test may detect colon cancer. The U.S. Food and Drug Administration has approved an at-home colon cancer test. ... But if you miss those polyps and they grow in the colon, you could be facing serious surgery, or even the possible spread of ...

https://thechart.blogs.cnn.com/2014/08/14/new-at-home-test-may-detect-colon-cancer/comment-page-11/?replytocom=3077275

Flatulency; wind colic in ascending colon; worse, before breakfast. Burning in abdomen and anus ...

https://www.abchomeopathy.com/r.php/Nat-s/Boger

Right ascending colon. I took 7 of 12 folfox. Last treatment 5/09. Taken off due to reaction. I felt fine the day I started ... Right ascending colon. I took 7 of 12 folfox. Last treatment 5/09. Taken off due to reaction. I felt fine the day I started ... Right ascending colon. I took 7 of 12 folfox. Last treatment 5/09. Taken off due to reaction. I felt fine the day I started ... My tumor was in my sigmoid colon. I dont know anything about rectum or anal..... peace, emily. p.s. I have remained cancer ...

https://csn.cancer.org/discussion/comment/981230

Or getting the nerve up to embark on such a project without needing colon hydrotherapy afterward.. Hmm.. Kreutzer…. Hm. ... Beach Romance, Coleridge-Taylor violin concerto, Mozart K454, Lark Ascending. Something like that. Ill have a lot of fun ...

https://www.violinist.com/blog/Mle/201111/12910/

Ascending colon 2 . Taenia coli (free) 3 . Cecum 4 . Paracolic sulcus 5 . Omental taenia coli ...

https://lane.stanford.edu/biomed-resources/bassett/bassettView.html?bn=139-7

Semicolon on Windows, colon otherwise. SCANDIR_SORT_ASCENDING. (int) SCANDIR_SORT_DESCENDING. (int) SCANDIR_SORT_NONE. (int) ...

http://docs.php.net/manual/en/dir.constants.php

My colon contracts. Bile ascends in my gorge. I hate myself and I hate everyone attached to the effort. ...

https://stevenpressfield.com/2013/01/opportunities-are-bullshit/?replytocom=56927

ascending (right) 863.41. *. with open wound into cavity 863.51. *. descending (left) 863.43. *. with open wound into cavity ... Short description: TRANSVERSE COLON INJ-CL.. *ICD-9-CM 863.42 is a billable medical code that can be used to indicate a ... Injury to transverse colon without open wound into cavity. * ... colon 863.40. *. with*. open wound into cavity 863.50. *. ... 2015/16 ICD-10-CM S36.501A Unspecified injury of transverse colon, initial encounter ...

http://www.icd9data.com/2009/Volume1/800-999/860-869/863/863.42.htm

The rest of your large intestine (ascending and descending colon) was.... 4/20/2022 5:35 PM ...

https://www.healingwell.com/community/profile.aspx?f=38&m=4171708&p=153367

Rift Guide&colon; Carnival of the Ascended Mini Games Slideshow 0 comments ... Want to know what to do for each of the mini-games at Rifts Carnival of the Ascended? Check this article out! ...

https://www.gameskinny.com/tag/mini-games/

Neurons number in the myenteric plexos of the ascending colon of rats. A comparative study using two staining techniques. Arqs ... 2007), in the proximal colon (Furlan et al. 2002). We can justify the controversial results for the NADPH-dp neurons in Group D ... Effects of protein and vitamin B deficiency on blood parameters and myenteric neurons of the colon of rats. Arqs Neuropsiquiatr ... Effect of the ascorbic acid treatment on the nadhd-positive myenteric neurons of diabetic rats proximal colon. Braz. Arch. Biol ...

https://www.scielo.br/j/pvb/a/cTpXN5YC5GYxSW9VqZGZBnx/?lang=en

The colon has three parts: the ascending colon and the transverse colon, which absorb fluids and salts; and the descending ... The colon extends from the cecum up the right side of the abdomen, across the upper abdomen, and then down the left side of the ... Bacteria in the colon help to digest the remaining food products.. *The rectum is where feces are stored until they leave the ...

https://www.kidshealth.org/AetnaBetterHealthMichigan/en/teens/digestive-system.html

The Effect of Experimental Fusarium Mycotoxicosis on Microbiota Diversity in Porcine Ascending Colon Contents by Małgorzata ... were determined in the contents of the ascending colon. The influence of mycotoxins on the functional diversity of the colonic ... on the colon microbiota. An experiment was conducted for 42 days on gilts, randomly assigned to [...] Read more. ... on the colon microbiota. An experiment was conducted for 42 days on gilts, randomly assigned to four groups and administered ...

https://www.mdpi.com/2072-6651/6/7

Amoxicillin has been associated with hemorrhagic, sometimes inflammatory colitis, which typically affects the ascending colon. ...

https://www.drugs.com/sfx/augmentin-es-600-side-effects.html

Your colon is an integral part of the digestive system, also known as your gastrointestinal tract (GI). ... Shankhprakashalana - Colon Cleansing with Yoga. By Jared McAllister on April 29, 2019 in Colon Cleanse Blog with 0 Comments ... 10 Surprising Colon Facts. By Jared McAllister on October 26, 2022 in Colon Cleanse Blog ... Recommended Colon Cleansers. 2019s top rated, BEST colon cleanse pills, drinks, and detox supplements for weight loss, ...

https://coloncleansers.net/colon-facts

colon, ascending 40405 trachea 38285 lung, carcinoma, A549 27590 human DNA 500 ng 9541 ... colon, transverse 62300 kidney 137204 lung 58777 liver 85484 leukemia, HL-60 48972 fetal brain 43774 yeast total RNA ... colon, descending 60792 skeletal muscle 163430 placenta 80932 pancreas 79718 HeLa S3 32213 fetal heart 55979 yeast tRNA ...

https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-2-40/tables/2

After the food leaves your cecum, it continues in a tube that goes up on the right side of your body called the ascending colon . (kid-facts.com)
lymph nodes (3 cm-5 cm) mostly in the ileocecal region, Clinical Manifestations and Surgical Findings and substantial edema involving one segment of small bowel, cecum, or ascending colon. (cdc.gov)
The cecum is the beginning of the colon, where the small intestine empties into the large intestine. (cancer.org)
The ascending colon, transverse colon, descending colon, and sigmoid colon are other parts of the colon after the cecum. (cancer.org)
Terminal ileum, cecum, ascending and proximal transverse colon eviscerated through the small midline incision. (sages.org)
Your colon begins at the lower right hand corner of your abdomen, where it's called your cecum. (drbenkim.com)
From your cecum, your colon travels up the right side of your abdomen, where it's called your ascending colon. (drbenkim.com)
Once enough liquid waste material accumulates in your cecum (the first part of your large intestine), the waste material begins to move up your ascending colon. (drbenkim.com)
Cecal perforation due to colon tumor that spanned from the cecum to the proximal third of the ascending colon, in addition, a transverse ileum angiostrongyliasis in an elderly anastomosis was performed, without further complication. (bvsalud.org)
The segment of LARGE INTESTINE between the CECUM and the TRANSVERSE COLON . (bvsalud.org)
In comparison with the descending colon, sigmoid colon, and rectum, the cecum and ascending colon are saccular, are larger in diameter, and have thinner walls. (medscape.com)

At its narrowest point (the sigmoid colon) it's a little less than 1 inch wide. (coloncleansers.net)
Synchronous transverse and sigmoid colon volvulus are very rare. (scirp.org)
We report the case of a 23-year-old man who underwent emergency surgery for sigmoid colon volvulus. (scirp.org)
An intraoperative finding of transverse colon volvulus associated with sigmoid colon volvulus was made. (scirp.org)
S ynchronous volvulus of the transverse and sigmoid colon is a surgical emergency. (scirp.org)
It is necessary to know how to evoke the diagnosis in a case of sigmoid colon volvulus, to avoid inadequate management with dramatic consequences. (scirp.org)
We report a case of synchronous volvulus of sigmoid colon and transverse colon treated at the Gabriel Touré University Hospital with a review of the literature on diagnostic and therapeutic aspects. (scirp.org)
Ascending colon, descending colon, and sigmoid colon located outside the thickened enhanced peritoneum. (diagnosticimaging.com)
Flexible sigmoidoscopy enables the physician to look at the inside of the large intestine from the rectum through the last part of the colon, called the sigmoid or descending colon. (news24.com)
Material passes through the ascending, transverse, descending and sigmoid portions of the colon, and finally into the rectum. (medlineplus.gov)
Your colon then makes one last turn toward the middle of your lower abdomen, forming an "S" shaped segment that's called your sigmoid colon. (drbenkim.com)
Your sigmoid colon empties waste materials into your rectum, which is like a storage pouch that retains your feces until contractions in your large intestine stimulate a bowel movement. (drbenkim.com)
The sigmoid arteries, rectosigmoid arteries, and branches of the IMA supply the sigmoid colon. (medscape.com)
The vagus nerve supplies the parasympathetic tone from the upper gastrointestinal (GI) tract to the splenic flexure, and the sacral parasympathetic nerves (S2 to S5) supply the left colon, sigmoid, and rectum. (medscape.com)
The sigmoid colon is a short curving of the colon, just before the rectum. (car-ix.net)
A subsequent colonoscopy performed 5 years later again showed two small sessile polyps in the sigmoid colon, while the remaining segments showed no abnormality. (endoscopy-colon-explorer.com)

[ 2 ] Mucosal inflammation in UC extends from the rectum to the proximal colon. (medscape.com)
Removal of the entire colon and the rectum is called a proctocolectomy. (medlineplus.gov)
Removal of all of the colon but not the rectum is called subtotal colectomy. (medlineplus.gov)
The colon ends at the rectum, where waste is stored until it exits through the anus. (cancer.org)
This surgery involves removing the colon and rectum and using the last part of the small intestine (the ileum) to create an internal pouch, which is typically J-shaped. (coloncleansers.net)
The Anal Canal and Rectum: Their Varying Relationship and Its Effect on Anal Continence, Diseases of the Colon and Rectum 1966: 9, 449-452. (naturesplatform.com)
They also use it to look for early signs of cancer in the descending colon and rectum. (news24.com)
With flexible sigmoidoscopy, the physician can see bleeding, inflammation, abnormal growths, and ulcers in the descending colon and rectum. (news24.com)
The physician will insert a short, flexible, lighted tube into your rectum and slowly guide it into your colon. (news24.com)
The scope transmits an image of the inside of the rectum and colon, so the physician can carefully examine the lining of these organs. (news24.com)
If anything unusual is in your rectum or colon, like a polyp or inflamed tissue, the physician can remove a piece of it using instruments inserted into the scope. (news24.com)
The colon and rectum must be completely empty for flexible sigmoidoscopy to be thorough and safe, so the physician will probably tell you to drink only clear liquids for 12 to 24 hours beforehand. (news24.com)
Patients with stage IV adenocarcinoma of the colon/rectum diagnosed from 2010 to 2013 were extracted from SEER data. (jnccn.org)
Your colon and rectum are collectively referred to as your large intestine, which is the last part of your digestive tract. (drbenkim.com)
Mass peristalsis serves to push waste materials from your transverse colon all the way to your rectum. (drbenkim.com)

Background and Aim Colon capsule endoscopy has already been used for colon visualization and detection of polyps but its applicability to inflammatory bowel disease is still unconfirmed. (medscape.com)
Cologuard) doesn't really detect polyps that could be the beginning of colon cancer,' Cho said. (cnn.com)
But if you miss those polyps and they grow in the colon, you could be facing serious surgery, or even the possible spread of the cancer. (cnn.com)
The prevalences of bowel diseases (hemorrhoids, appendicitis, polyps, ulcerative colitis, irritable bowel syndrome, diverticular disease, and colon cancer) are similar in South African whites and in populations of prosperous western countries. (naturesplatform.com)
Flexible sigmoidoscopy is not sufficient to detect polyps or cancer in the ascending or transverse colon (two-thirds of the colon). (news24.com)
A recent report from Douglas Rex describes a case of a patient submitted to a total colonoscopy which detected two small polyps in the transverse colon. (endoscopy-colon-explorer.com)

The SMA gives rise to the ileocolic, right colic, and middle colic arteries, which supply the ileocecal region, the ascending colon, and the proximal transverse colon, respectively. (medscape.com)

By the end of September I had the diagnosis: poorly differentiated adenocarcinoma of the ascending colon. (trinityfoundation.org)

The large bowel is also called the large intestine or colon. (medlineplus.gov)
Certain health conditions (such as colon cancer and inflammatory bowel disease) may require the removal of a person's colon. (coloncleansers.net)
In the colon, this material is made into a stool that is passed during a bowel movement. (coloncleansers.net)
This helps prevent "fecal stagnation," a prime factor in colon cancer , appendicitis and inflammatory bowel disease . (naturesplatform.com)
To have healthy bowel movements, it's essential that you support colon and rectal health with all of your daily choices. (drbenkim.com)
This is why bowel movements and colon health are intricately tied to emotional states like feeling calm or anxious. (drbenkim.com)
The abdominal CT images revealed a cluster of prominent bowel loops, likely jejunal, in the left upper quadrant region, lateral to the ascending duodenum pointing inwardly. (medscape.com)
A left paraduodenal hernia is a cluster of bowel loops in the left upper quadrant lateral to the ascending duodenum. (medscape.com)
In congenital stenosis, a narrow segment of colon is observed, but bowel continuity is maintained. (medscape.com)
Emergent computerized tomography (CT) scan with contrast of the abdomen results show possible free air bubbles in close proximity to the ascending colon wall, may suggest bowel perforation. (cdc.gov)
A group of dietary carbohydrates called FODMAPs are rapidly fermented in the large bowel (colon) producing gases as we have shown recently using MRI (Magnetic Resonance Imaging). (ukri.org)
STUDY 6: We will give the cellulose with inulin daily for 3 weeks to IBS patients before assessing gas and colonic volumes using MRI, relevant bowel symptoms (gas, pain, bloating) and stool fermentation pathways using our model colon. (ukri.org)

The growth pattern is only important because it helps determine when you will need your next colonoscopy to make sure you don't develop colon cancer in the future. (cancer.org)
The U.S. Food and Drug Administration has approved an at-home colon cancer test. (cnn.com)
And the longer the waste is in contact with the wall of the colon, not only does it get reabsorbed into the blood stream, it begins to mutilate the wall membrane that eventually leads to leaky gut , colon or rectal cancer. (juicing-for-health.com)
The Monday following my diagnosis we were in Durham, North Carolina, consulting Dr. Douglas Tyler at Duke University Hospital, one of the best colon cancer surgeons in the country. (trinityfoundation.org)
This large population-based study showed that among patients initially diagnosed with stage IV CRC, right-sided colon cancer was associated with greater risk of death compared with left-sided cancer, and KRAS mutations were only associated with risk of death in left-sided colon cancer. (jnccn.org)
In preclinical trials, Sirolimus (rapamycin) was shown effective in reducing tumors in mouse models of familial adenomatous polyposis and colon cancer with APC deficient tumors ( PMID: 18768809 , PMID: 20080688 ). (jax.org)
In a preclinical study, mouse models of colon cancer carrying an APC 716del mutation had reduced polyp formation after treatment with MF tricyclic ( PMID: 23843721 ). (jax.org)
Low FODMAP diets, although widely adopted, are expensive, inconvenient and may have negative effects on health by excluding high fibre foods (HFF) that protect against obesity-related diseases and colon cancer. (ukri.org)

What is a polyp in the colon? (cancer.org)
A polyp is a projection (growth) of tissue from the inner lining of the colon into the lumen (hollow center) of the colon. (cancer.org)
An adenoma is a polyp made up of tissue that looks much like the normal lining of your colon, although it is different in several important ways when it is looked at under the microscope. (cancer.org)

Both surgeons gave the same advice: immediate resection of the colon followed by chemotherapy. (trinityfoundation.org)

Radiological investigations (USG and CECT whole abdomen) reported an asymmetrical ill-defined growth in ascending colon and caecum with loco-regional lymphadenopathy. (who.int)

The Landzert fossa is located behind the ascending or fourth part of the duodenum and is formed by the lifting up of a peritoneal fold by the inferior mesenteric vein and ascending left colic artery as they run along the lateral side of the fossa. (medscape.com)

Here are 10 colon facts to help you become better acquainted with your large intestine, including the function and location of your colon, how long your intestines are, and more. (coloncleansers.net)
The colon is responsible for finishing the digestive process of digestion by absorbing water and electrolytes from food leaving the small intestine. (coloncleansers.net)
The small intestine surrounded by the ascending, transverse, and descending colon, and the paracolic gutters are contained within the infracolic compartment. (wikipedia.org)
At the end of the small intestine, the food enters the large intestine (colon) for a final digestive process and finally, elimination. (juicing-for-health.com)
Unlike the small intestine that absorb foods and nutrients, the colon extracts water and electrolytes, and form what's left of the wastes into feces to be eliminated. (juicing-for-health.com)
Securely seals the ileocecal valve, between the colon and the small intestine. (naturesplatform.com)
After food passes through your stomach and small intestine, the remaining material, mostly waste products in liquid form, move on to the your colon, which is the first part of your large intestine. (drbenkim.com)

The colon is approximately 5 feet long and is in the shape of an upside-down U that goes up one side of the abdomen, across the top, and down the other side. (coloncleansers.net)
Just below your lower left ribs, it makes another turn and travels down the left side of your abdomen - this portion is called your descending colon. (drbenkim.com)
The ascending colon travels up the right side of the abdomen. (car-ix.net)
The transverse colon runs across the abdomen. (car-ix.net)
The descending colon travels down the left abdomen. (car-ix.net)

As the wall tension of the colon increases, ischemia with longitudinal splitting of the serosa, herniation of the mucosa, and perforation (including iatrogenic perforation during open or laparoscopic procedures) can occur. (medscape.com)

The peritoneal cavity is divided into two compartments - one above, and one below the transverse colon . (wikipedia.org)
The peritoneal cavity is divided by the transverse colon (and its mesocolon ) into an upper supracolic compartment , and a lower infracolic compartment . (wikipedia.org)

Tiene un trayecto ascendente desde el ciego hasta la superficie caudal del lóbulo derecho del HÍGADO en donde se curva pronunciadamente hacia la izquierda, formando la flexura cólica derecha. (bvsalud.org)

However, we observed that the characteristic endoscopic findings of the GI tract of ATLL patients consist of multiple mucosal protrusions and ulcers, GI wall thickening, and the presence of similar macroscopic findings in various GI organs such as the stomach and colon. (go.jp)
Beside description of the endoscopic findings, in case of detection of a lesion along the colon, the operator should express his/her opinion regarding the indication to endoscopic or surgical treatment. (endoscopy-colon-explorer.com)

Seminars in Colon and Rectal Surgery. (wustl.edu)

All three of these files start with a Unicode code point as a hexadecimal string, with code points appearing in ascending order. (ubuntu.com)
This file followed the same format as unifont.hex with a first field that was a Unicode code point in hexadecimal, followed by a colon (':') field separator, followed by a second field that was a hexadecimal string representing a glyph bitmap. (ubuntu.com)

IMSEAR at SEARO: Hodgkin lymphoma involving ascending colon and mesenteric lymphnodes: A rare entity. (who.int)

The left colic artery, arising from the IMA, supplies the left portion of the transverse colon and the descending colon. (medscape.com)
The default is now to list comments in ascending order instead of descending order, and order=DESC must be set to list comments in descending order. (chessvariants.com)
Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column. (jax.org)

Colonic volvulus occurs on mobile segments of the colon and results in intestinal obstruction by strangulation. (scirp.org)

We will also measure acidity in the colon in response to inulin and how the cellulose mix changes it, using a 'Smart pH pill' (a swallowed pill which passes through the gut emitting a radio signal indicating acidity). (ukri.org)

Components derived from the gut proper, including the stomach and colon , develop as swellings or dilatations of the primitive gut. (bionity.com)

colonic stenosis is a condition in which a part of the colon is very narrow, resulting in a partial blockage. (medscape.com)
One theory, examined in a 1988 study by Lee et al, is that increased sympathetic tone to the colon results in the inhibition of colonic motility. (medscape.com)
FODMAPs cause abdominal discomfort, bloating and flatulence by their rapid colonic fermentation which produces gas and distends the colon. (ukri.org)

The aim of this study was to assess the feasibility of evaluating the severity of mucosal inflammation in patients with ulcerative colitis (UC) using a second-generation colon capsule endoscope (CCE-2). (medscape.com)

Your colon is divided along its length into small pouches called haustra. (drbenkim.com)

Or getting the nerve up to embark on such a project without needing colon hydrotherapy afterward. (violinist.com)
You will feel better afterward when the air leaves your colon. (news24.com)

Surgical exploration revealed an ascending colon mass with retroperitoneal lymphadenopathy. (who.int)

After every substantial meal, your colon experiences a much larger contractile wave, called "mass peristalsis. (drbenkim.com)

CCE-2 procedure completion rate and the colon cleansing level with a 4-point grading scale (poor, fair, good, and excellent) were evaluated in Phase 2. (medscape.com)
A CCE procedure requires extensive, multi-step preparation [ 9 ] for colon cleansing and the capsule booster. (medscape.com)
During the colonoscopy, the endoscopist should perform a punctual description of the procedure and take pictures in the various segments explored, both in case of normal and pathological colon. (endoscopy-colon-explorer.com)

If you have diarrhea, the stool hasn't been in your colon long enough to adequately absorb enough liquid to make the stool firm. (coloncleansers.net)

Patient is taken to the operating room (OR) for possible colon repair. (cdc.gov)

We have developed a laboratory model colon which simulates conditions in the colon and allows us to measure the breakdown products of inulin including gas, something very difficult / impossible in actual patients because the colon is so inaccessible. (ukri.org)

Your colon then begins the process of eliminating the waste through the stool (feces). (coloncleansers.net)
Some people have so much compacted feces in the colon that the passage through which the feces are forced to travel is reduced to only a passage as thin as a pencil. (juicing-for-health.com)

In ordered lists, they are usually displayed with an ascending counter on the left, such as a number or letter. (mozilla.org)
The lower 6 thoracic segments supply the sympathetic tone to the right colon, whereas lumbar segments 1-3 supply the left colon. (medscape.com)

STUDY 3: Will use stool samples from Study 1 subjects in our laboratory model colon to correlate gas production with other break down products of inulin including SCFAs to see how these alter with differing gas production. (ukri.org)

Citation style sort is year ascending, and then by author or title. (mskcc.org)

I'm going to do a mix of dumping my notes in a play-by-play fashion with possible sidebars for commenting on what I experienced personally so that I have a record of this to look back on as I move forward with Ascend Project planning and execution. (lukasblakk.com)

Separate multiple email address with semi-colons (up to 5). (mhmedical.com)

Anatomy26

Organisms10

Diseases56

Chemicals and Drugs76

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Phenomena and Processes43

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science5

Health Care9

Distinguishing right from left colon by the pattern of gene expression. (1/37)

Effects of nifedipine and nickel on plateau potentials generated in submucosal interstitial cells distributed in the mouse proximal colon. (2/37)

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. (3/37)

Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? (4/37)

A rare case of ascending colon actinomycosis mimicking cancer. (5/37)

Treatment of resistant distal intestinal obstruction syndrome with a modified antegrade continence enema procedure. (6/37)

The retroperitoneal surface in distal caecal and proximal ascending colon carcinoma: the Cinderella surgical margin? (7/37)

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. (8/37)

Colonic Neoplasms

Colon, Descending

Colon, Sigmoid

Colon, Ascending

Colon, Transverse

HT29 Cells

Azoxymethane

Diverticulum, Colon

Intestinal Mucosa

Colonic Diseases

Adenocarcinoma

Colorectal Neoplasms

1,2-Dimethylhydrazine

Colitis

Cell Line, Tumor

Dimethylhydrazines

Colectomy

Colonoscopy

Tumor Cells, Cultured

Adenoma

Caco-2 Cells

Sigmoid Neoplasms

Rectal Neoplasms

Carcinogens

Gastrointestinal Motility

Rectum

Gene Expression Regulation, Neoplastic

Cecum

Dextran Sulfate

Apoptosis

Mice, Nude

Precancerous Conditions

Butyrates

Anticarcinogenic Agents

RNA, Messenger

Intestinal Polyps

Rats, Inbred F344

Colitis, Ulcerative

Intestine, Large

beta Catenin

Immunohistochemistry

Cell Proliferation

Carcinoma

Colostomy

Antineoplastic Agents

Genes, APC

Cecal Neoplasms

Aberrant Crypt Foci

Sigmoid Diseases

Cell Division

Neoplasm Transplantation

Intestines

Carcinoembryonic Antigen

Enema

Mucins

Ileum

Trinitrobenzenesulfonic Acid

Reverse Transcriptase Polymerase Chain Reaction

Cathartics

Feces

Intestine, Small

Fluorouracil

Blotting, Western

Mice, Inbred BALB C

Transplantation, Heterologous

Intestinal Neoplasms

Cyclooxygenase 2

Neoplasm Proteins

Adenomatous Polyposis Coli

Tumor Markers, Biological

Dose-Response Relationship, Drug

Microsatellite Instability

Intestinal Obstruction

Adenomatous Polyposis Coli Protein

Signal Transduction

Diverticulitis, Colonic

Neoplasm Staging

Diet

Mice, Inbred C57BL

Barium Sulfate