Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
The circulation of blood through the CORONARY VESSELS of the HEART.
A number of ligaments on either side of, and serving as a radius of movement of, a joint having a hingelike movement. They occur at the elbow, knee, wrist, metacarpo- and metatarsophalangeal, proximal interphalangeal, and distal interphalangeal joints of the hands and feet. (Stedman, 25th ed)
A polygonal anastomosis at the base of the brain formed by the internal carotid (CAROTID ARTERY, INTERNAL), proximal parts of the anterior, middle, and posterior cerebral arteries (ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; POSTERIOR CEREBRAL ARTERY), the anterior communicating artery and the posterior communicating arteries.
Recesses of the kidney pelvis which divides into two wide, cup-shaped major renal calices, with each major calix subdivided into 7 to 14 minor calices. Urine empties into a minor calix from collecting tubules, then passes through the major calix, renal pelvis, and ureter to enter the urinary bladder. (From Moore, Clinically Oriented Anatomy, 3d ed, p211)
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
The circulation of blood through the BLOOD VESSELS of the BRAIN.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Radiography of the vascular system of the brain after injection of a contrast medium.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
Radiography of blood vessels after injection of a contrast medium.
The circulation of BLOOD through the LIVER.
Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
The ligament that travels from the medial epicondyle of the FEMUR to the medial margin and medial surface of the TIBIA. The medial meniscus is attached to its deep surface.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
Application of a ligature to tie a vessel or strangulate a part.
The condition of an anatomical structure's being constricted beyond normal dimensions.
Use of a balloon CATHETER to block the flow of blood through an artery or vein.
The veins and arteries of the HEART.
The flow of BLOOD through or around an organ or region of the body.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Motion pictures of the passage of contrast medium through blood vessels.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.
The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
The arterial blood vessels supplying the CEREBRUM.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Changes in the observed frequency of waves (as sound, light, or radio waves) due to the relative motion of source and observer. The effect was named for the 19th century Austrian physicist Johann Christian Doppler.
Pathological conditions of intracranial ARTERIES supplying the CEREBRUM. These diseases often are due to abnormalities or pathological processes in the ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; and POSTERIOR CEREBRAL ARTERY.
Narrowing or constriction of a coronary artery.
Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)
The main artery of the thigh, a continuation of the external iliac artery.
A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Branch of the common carotid artery which supplies the exterior of the head, the face, and the greater part of the neck.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
The development of new BLOOD VESSELS during the restoration of BLOOD CIRCULATION during the healing process.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Radiographic visualization or recording of a vein after the injection of contrast medium.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Elements of limited time intervals, contributing to particular results or situations.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
The vessels carrying blood away from the heart.
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation.
The circulation of the BLOOD through the LUNGS.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

The effect of cardiac contraction on collateral resistance in the canine heart. (1/1214)

We determined whether the coronary collateral vessels develop an increased resistance to blood flow during systole as does the cognate vascular bed. Collateral resistance was estimated by measuring retrograde flow rate from a distal branch of the left anterior descending coronary artery while the main left coronary artery was perfused at a constant pressure. Retrograde flow rate was measured before and during vagal arrest. We found that in 10 dogs the prolonged diastole experienced when the heart was stopped caused no significant change in the retrograde flow rate, which indicated that systole has little effect on the collateral resistance. However, when left ventricular end-diastolic pressure was altered by changing afterload or contractility, a direct relationship between end-diastolic pressure and collateral resistance was noted.  (+info)

Effect of coronary occlusion on left ventricular function with and without collateral supply during beating heart coronary artery surgery. (2/1214)

OBJECTIVE: To study the effects of coronary occlusion and collateral supply on left ventricular (LV) function during beating heart coronary artery surgery. DESIGN: Prospective intraoperative study, performed at baseline, during wall stabilisation, coronary artery occlusion, and 2 and 10 minutes after reperfusion. Transoesophageal M mode echocardiograms, simultaneous high fidelity LV pressure, and thermodilution cardiac output were measured. LV anterior wall thickening, thinning velocities, thickening fraction, regional work, and power production were derived. Asynchrony during the isovolumic periods was quantified as cycle efficiency. SETTING: Tertiary referral cardiac centre. PATIENTS: 14 patients with stable angina, mean (SD) age 62 (7) years, undergoing left anterior descending artery grafting using the "Octopus" device. RESULTS: Collaterals were absent in nine patients and present in five. Epicardial stabilisation did not affect LV function. Results are expressed as mean (SD). Coronary occlusion (15.6 (2) minutes) depressed anterior wall thickening (1.4 (0.6) v 2.6 (0.6) cm/s) and thinning velocities (1.4 (0.5) v 3.0 (0.6) cm/s), regional work (2.2 (0.8) v 4.6 (0.6) mJ/cm2), and power (21 (4) v 33 (5) mW/cm2) in patients without collaterals (p < 0.05 for all), but only wall thinning (3.5 (0.5) v 4.8 (0.5) cm/s, p < 0.05) in patients with collaterals. All returned to baseline within 10 minutes of reperfusion. Cycle efficiency and regional work were impaired at baseline and fell during occlusion, regardless of collaterals. Within 10 minutes of reperfusion both had increased above baseline. CONCLUSIONS: Coronary occlusion for up to 15 minutes during beating heart coronary artery surgery depressed standard measurements of systolic and diastolic anterior wall function in patients without collaterals, but only those of diastolic function in patients with collaterals. Regional synchrony decreased in both groups. All disturbances regressed within 10 minutes of reperfusion.  (+info)

Late massive haemoptyses from bronchopulmonary collaterals in infarcted segments following pulmonary embolism. (3/1214)

Massive, recurrent haemoptyses requiring blood transfusions occurred in a patient who had been diagnosed as having pulmonary thromboembolism 3 months earlier. To the authors' knowledge this is the first case report of this kind, in which massive haemoptyses were proved to be caused by large bronchopulmonary collaterals that had developed in the infarcted lung segments affected by embolism. Selective embolization of the collaterals proved to be therapeutic and life saving.  (+info)

Isolated femoropopliteal bypass graft for limb salvage after failed tibial reconstruction: a viable alternative to amputation. (4/1214)

PURPOSE: Femoropopliteal bypass grafting procedures performed to isolated popliteal arteries after failure of a previous tibial reconstruction were studied. The results were compared with those of a study of primary isolated femoropopliteal bypass grafts (IFPBs). METHODS: IFPBs were only constructed if the uninvolved or patent popliteal segment measured at least 7 cm in length and had at least one major collateral supplying the calf. When IFPB was performed for ischemic lesions, these lesions were usually limited to the digits or small portions of the foot. Forty-seven polytetrafluoroethylene grafts and three autogenous reversed saphenous vein grafts were used. RESULTS: Ankle brachial pressure index (ABI) increased after bypass grafting by a mean of 0.46. Three-year primary life table patency and limb-salvage rates for primary IFPBs were 73% and 86%, respectively. All eight IFPBs performed after failed tibial bypass grafts remained patent for 2 to 44 months, with patients having viable, healed feet. CONCLUSION: In the presence of a suitable popliteal artery and limited tissue necrosis, IFPB can have acceptable patency and limb-salvage rates, even when a polytetrafluoroethylene graft is used. Secondary IFPB can be used to achieve limb salvage after failed tibial bypass grafting.  (+info)

Relief of obstructive pelvic venous symptoms with endoluminal stenting. (5/1214)

PURPOSE: To select patients for percutaneous transluminal stenting of chronic postthrombotic pelvic venous obstructions (CPPVO), we evaluated the clinical symptoms in a cohort of candidates and in a series of successfully treated patients. METHODS: The symptoms of 42 patients (39 women) with CPPVO (38 left iliac; average history, 18 years) were recorded, and the venous anatomy was studied by means of duplex scanning, subtraction venography, and computed tomography or magnetic resonance imaging. Successfully stented patients were controlled by means of duplex scanning and assessment of symptoms. RESULTS: The typical symptoms of CPPVO were reported spontaneously by 24% of patients and uncovered by means of a targeted interview in an additional 47%. Of 42 patients, 15 had venous claudication, four had neurogenic claudication (caused by dilated veins in the spinal canal that arise from the collateral circulation), and 11 had both symptoms. Twelve patients had no specific symptoms. Placement of a stent was found to be technically feasible in 25 patients (60%), was attempted in 14 patients, and was primarily successful in 12 patients. One stent occluded within the first week. All other stents were fully patent after a mean of 15 months (range, 1 to 43 months). Satisfaction was high in the patients who had the typical symptoms, but low in those who lacked them. CONCLUSION: Venous claudication and neurogenic claudication caused by venous collaterals in the spinal canal are typical clinical features of CPPVO. We recommend searching for these symptoms, because recanalization by means of stenting is often feasible and rewarding.  (+info)

Quantification of collateral flow in humans: a comparison of angiographic, electrocardiographic and hemodynamic variables. (6/1214)

OBJECTIVES: Evaluation of collateral vascular circulation according to hemodynamic variables and its relation to myocardial ischemia. BACKGROUND: There is limited information regarding the hemodynamic quantification of recruitable collateral vessels. METHODS: Angiography of the donor coronary artery was performed before and during balloon coronary occlusion in 63 patients with one vessel disease. Patients were divided into groups of those with an absence of collateral vessels (group 1, n = 10), those with recruitable collateral vessels (group 2, n = 23) and those with spontaneously visible collateral vessels (group 3, n = 30). During balloon inflation the coronary wedge/aortic pressure ratio (Pw/Pao) was determined as were collateral blood flow velocity variables, using a 0.014" Doppler guide wire. Myocardial ischemia was defined as > or =0.1 mV ST-shift on a 12 lead electrocardiogram at 1 min coronary occlusion. RESULTS: Myocardial ischemia was present in all patients of group 1, in 14 patients of group 2 and in 3 patients of group 3. Recruitable collateral flow without ischemia showed similar hemodynamic values as in group 3 while these values were similar to group 1 in regard to the presence of recruitable collateral vessels showing ischemia. Logistic regression analysis revealed both Pw/Pao and Vi(col) as independent predictors for the function of collateral vessels. CONCLUSIONS: Hemodynamic variables of collateral vascular circulation are better markers of the functional significance of collateral vessels than is coronary angiography. The total collateral blood flow velocity integral and coronary wedge/aortic pressure ratio are good and independent predictors of the function of collateral vessels producing complementary information.  (+info)

Recovery of contractility of viable myocardium during inotropic stimulation is not dependent on an increase of myocardial blood flow in the absence of collateral filling. (7/1214)

OBJECTIVES: The purpose of this study was to determine whether contractile recovery induced by dobutamine in dysfunctioning viable myocardium supplied by nearly occluded vessels is related to an increase in blood flow in the absence of collaterals. BACKGROUND: Dobutamine is used to improve contractility in ventricular dysfunction during acute myocardial infarction. However, it is unclear whether a significant increase in regional blood flow may be involved in dobutamine effect. METHODS: Twenty patients with 5- to 10-day old anterior infarction and > or =90% left anterior descending coronary artery stenosis underwent 99mTc-Sestamibi tomography (to assess myocardial perfusion) at rest and during low dose (5 to 10 microg/kg/min) dobutamine echocardiography. Rest echocardiography and scintigraphy were repeated >1 month after revascularization. Nine patients had collaterals to the infarcted territory (group A), and 11 did not (group B). RESULTS: Baseline wall motion score was similar in both groups (score 15.9+/-1.3 vs. 17.4+/-2.0, p = NS), whereas significant changes at dobutamine and postrevascularization studies were detected (F[2,30] = 409.79, p < 0.0001). Wall motion score improved significantly (p < 0.001) in group A both at dobutamine (-5.3+/-2.2) and at postrevascularization study (-5.5+/-1.9), as well as in group B (-3.9+/-2.8 and -4.5+/-2.4, respectively). Baseline 99mTc-Sestamibi uptake was similar in both groups (62.9+/-9.7% vs. 60.3+/-10.4%, p = NS), whereas at dobutamine and postrevascularization studies a significant change (F[2,30] = 65.17, p < 0.0001) and interaction between the two groups (F[2,30] = 33.14, p < 0.0001) were present. Tracer uptake increased significantly in group A both at dobutamine (+ 10.9+/-7.9%, p < 0.001) and at postrevascularization study (12.1+/-8.7%, p < 0.001). Conversely, group B patients showed no change in tracer uptake after dobutamine test (-0.4+/-5.8, p = NS), but only after revascularization (+8.8+/-7.2%, p < 0.001). CONCLUSIONS: The increase in contractility induced by low dose dobutamine infusion in dysfunctional viable myocardium supplied by nearly occluded vessels occurs even in the absence of a significant increase in blood flow.  (+info)

Angiographic abnormalities associated with alterations in regional myocardial blood flow in coronary artery disease. (8/1214)

To evaluate the association between alterations in myocardial blood flow and angiographic findings, myocardial blood flow was compared in 26 patients with asymergy, 15 patients with a similar extent of coronary artery disease but without asynergy, and 10 patients without coronary artery disease or obvious myocardial or valvular disease. Myocardial blood flow was measured at rest with an Anger camera and PDP-11/20 computer after the intracoronary injection of 133xenon. In comparison with the normal subjects, whole heart blood flow was significantly reduced in patients with asynergy. In addition, myocardial blood flow in regions of anteroapical asynergy was reduced (85-7 +/- 7-0 ml/min per 100 g3 in controls to 65-4 +/- 4-5, P less than 0-05) and a similar reduction was noted in regions of posterolateral asymergy (91-5 +/- 8-8 in controls to 66-8 +/- 5-0, P less than 0-05). In general, regional myocardial blood flow was reduced distal to left anterior descending or left circumflex stenosis of less than 50 per cent, with a trend toward further reduction distal to less than 75 per cent stenosis. In these same patients, the presence of anteroapical or posterolateral asynergy resulted in a similar trend to even greater reduction of flow. The effect of collaterals was variable: 7 of 8 patients without asynergy but with less than 75 per cent left anterior descending stenosis and collateral circulation to the lower left anterior descending quadrant had minimally reduced flows. However, in the 17 patients with anteroapical asynergy, regional myocardial blood flow was very similar in the 9 patients with collaterals compared with the 8 patients without them. This study suggests that the degree of coronary artery stenosis and presence of asynergy are both important in evaluating alterations in myocardial blood flow in coronary artery disease, while the role of collaterals remains uncertain.  (+info)

Collateral growth and coronary angiogenesis are chronic adaptations to myocardial ischemia. Collateralization helps to restore blood flow and as a result salvages myocardium in severely ischemic myocardial regions. Thus, good collateral development in patients with severe coronary artery disease (CAD) improves ventricular function and prognosis (1-3).. However, coronary collateral development is different among patients even with similar degrees of coronary artery stenosis. Several factors, such as diabetes mellitus (4) and duration of myocardial ischemic symptoms (5) have been reported to effect coronary collateral development. At the cellular level, inflammatory cells, especially monocytes have an important role in collateralization. In a series of experimental studies with animals, it has been shown that monocytes are important elements for development of collateral vessels (6-7). In a recent study, it has been demonstrated that increased circulating monocyte count is related to good ...
AbstractBackground:Well-developed coronary collateral circulation usually results in fewer infarct size, improved cardiac function, and fewer mortality. Traditional coronary risk factors (diabetes, hypertension, and smoking) have some effects on coronary collateral circulation. However, the associat
The possibility that variation in the extent of native collateral circulation is an important determinant of variation in ischemic injury when acute arterial occlusion occurs or disease becomes manifest has historically been overlooked or minimized-, with the exception of those who study or treat acute ischemic stroke7-14 (and references therein), some coronary investigators4-6,69 (and references therein), and among vascular surgeons who frequently encounter or perform arterial occlusions.70,71 This presumably extends, in part, from the small diameter typical of native collaterals in most healthy individuals that is beyond the resolution of digital angiography (,0.2 mm), from the misconception that such minute vessels cannot mediate significant flow in the acute setting until remodeling has occurred, and from the inability to experimentally change native collateral extent to test its importance. The latter restriction has begun to yield in recent studies in which collateral extent was found to ...
Since the first description of the coronary collateral circulation in 1958,15 extensive investigations have been performed to elucidate the mechanisms that stimulate coronary collateral growth. Buschmann and colleagues16 were able to show a significant increase in collateral formation after 7 weeks of intermittent external counterpulsation in 23 patients with stable CAD in comparison with an inactive control group. An increase of collateral blood flow was detected by Zbinden in a nonrandomized clinical trial in 40 patients10 following regular physical exercise, performed 3 times a week over 3 months. However, PCI of the diseased vessel was performed before exercise training was initiated, which eliminated any possible ischemic trigger of collateral formation.. The underlying mechanism for increasing collateral blood flow has been the center of considerable debate.17 There are 2 distinct mechanisms that can be activated in the presence of ischemia caused by a flow-limiting lesion in an epicardial ...
Collateral circulation affects the prognosis of patients with acute ischemic stroke (AIS) treated by thrombolysis. The present study performed a systematic assessment of the impact of the collateral circulation status on the outcomes of patients receiving thrombolysis treatment. Relevant full‑text articles from the Cochrane Library, Ovid, Medline, Embase and PubMed databases published from January 1, 2000 to November 1, 2016 were retrieved. The quality of the studies was assessed and data were extracted by 2 independent investigators. The random‑effects model was used to estimate the impact of good vs. poor collateral circulation, as well as baseline characteristics, on the outcome within the series presented as risk ratios. Subgroup analyses explored the potential factors that may interfere with the effects of the collateral circulation status on the outcome. A total of 29 studies comprising 4,053 patients were included in the present meta‑analysis. A good collateral circulation status ...
The assessment of adequate ulnar collateral supply to the hand is mandatory prior to the harvest of the radial artery as a conduit for coronary artery bypass grafting. However, there is currently no one test which is widely used in all centres. We report a new and objective method of assessing ulnar collateral supply to the hand prior to harvest of the radial artery. This technique involves assessing the presence of a hyperaemic flow response to occlusion of the radial artery using an intraoperative transit time flowmeter. We found this technique to be objective and reliable, and would advocate its use in patients with a positive Allens test ...
Coronary collateral circulation from the cardiac lumen was studied in 36 anesthetized, open-chest dogs with hearts beating in situ. The coronary arteries were cannulated and perfused from an isolated, nonradioactive blood source while 131I-labeled blood circulated through the cardiac lumen for 2 minutes. Ventricular fibrillation was then produced, and luminal blood samples and myocardial tissue samples were obtained for radioactive assay and calculation of the amount of luminal blood appearing as a part of the myocardial blood volume. These volumes were obtained from both ventricles and the atria under (1) normal antegrade coronary flow conditions, (2) myocardial ischemia, (3) left and right ventricular hypertension, and (4) coronary occlusion. Small quantities of luminal blood appeared in the left ventricular myocardium under normal coronary flow conditions while considerably larger amounts were found in the right ventricle and atria. There was no significant increase of the luminal ...
Besides severity of coronary obstruction [37, 38], numerous factors that could possibly attenuate the development and biological function of coronary collaterals have been reported such as old age [39], traditional risk factors for coronary artery disease [40-44], hyperlipoprotein (a) [45], hyperuricemia [46] and elevated serum levels of CRP [47], TNF-a [48], N-terminal pro-brain natriuretic peptide [38] and mimecan [49], and high neutrophil/lymphocyte ratio [50]. In contrast, higher plasma levels of MCP-1 [51] or apelin [52] were associated with better coronary collateral development. The presence and extent of spontaneously visible coronary collaterals was also affected by plasma chemokine concentrations, as higher collateralization was associated with increased concentration of the angiogenic ligand and decreased concentrations of angiostatic ligands, and interferon-c [53]. It is known that diabetes mellitus aggressively induces atherosclerosis and may be more susceptible to myocardial ...
TY - JOUR. T1 - Impaired leptomeningeal collateral flow contributes to the poor outcome following experimental stroke in the type 2 diabetic mice. AU - Akamatsu, Yosuke. AU - Nishijima, Yasuo. AU - Lee, Chih Cheng. AU - Yang, Shih Yen. AU - Shi, Lei. AU - An, Lin. AU - Wang, Ruikang K.. AU - Tominaga, Teiji. AU - Liu, Jialing. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Collateral status is an independent predictor of stroke outcome. However, the spatiotemporal manner in which collateral flow maintains cerebral perfusion during cerebral ischemia is poorly understood. Diabetes exacerbates ischemic brain damage, although the impact of diabetes on collateral dynamics remains to be established. Using Doppler optical coherent tomography, a robust recruitment of leptomeningeal collateral flow was detected immediately after middle cerebral artery (MCA) occlusion in C57BL/6 mice, and it continued to grow over the course of 1 week. In contrast, an impairment of collateral recruitment was evident in the Type 2 ...
Coronary heart disease (CHD) is a major health concern for Americans and people worldwide. Arteriogenesis, an adaptive remodeling process in which pre-existing collateral arterioles remodel to form large diameter conductance arteries, has received recent attention for its therapeutic potential in treating CHD, but the mechanisms regulating the process remain incompletely understood. In particular, little is known about how collateral flow, and the resulting effect of shear stress acting along the collateral vessel wall, regulates coronary collateralization. This Thesis combines a series of experimental systems to define the responses evoked in endothelial cells exposed to hemodynamic waveforms characteristic of coronary collateral vessels and the subsequent paracrine effects on smooth muscle cells. Initially, a lumped parameter model of the human coronary collateral circulation was used to simulate normal (NCC) and adaptive remodeling (ACC) coronary collateral shear stress waveforms. These ...
Further analysis of the IMS-III cohort of patients show that collateral status influence outcomes and those with intermediate collaterals seem to benefit the most from endovascular therapy. With the ESCAPE trial, collateral status was used as an inclusion criteria (patients with poor collaterals being excluded from the trial) and outcomes improved significantly in the endovascular group vs the IV tPA group. MR-CLEAN which was a study that did not use collateral status as an inclusion criteria did not have as significant overall good outcomes as the other published endovascular trials. Possibly because they included patients with poor collaterals, who dont benefit from either endovascular or IV tPA treatments as the infarct grows too rapidly for recanalization to have an effect. Had IMS-III recruited patients based on collateral status as in ESCAPE, we may have had a positive trial three years earlier. As we continue to understand the pathophysiological reasons for the success of the recent ...
Coronary artery disease (CAD) is the leading cause of death in industrialized countries. Current therapies for restoration of coronary flow are percutaneous coronary intervention (PCI) or surgical revascularization. However, inherent to them are procedure-related risks and the fact that CAD progression is not prevented. Additionally, up to one fourth of all CAD patients are not amenable to standard revascularization therapies. Thus, there is a need for alternative therapies. Coronary collaterals as natural bypasses are anastomoses without an intervening capillary bed between portions of the same coronary artery or between different coronary arteries. The coronary collateral circulation is prevalent in humans and in CAD the amount of collateral flow is directly related to infarct size, all-cause- and cardiac mortality. Thus, the goal is to promote collateral function in the sense of prophylactic myocardial salvage.. Coronary (collateral) blood flow occurs almost entirely during diastole. Fluid ...
Coronary collateral circulation plays an important role to protect myocardium from ischemia, preserve myocardial contractility and reduce cardiovascular events. Chronic kidney disease (CKD) is associated with poor coronary collateral development and
Previous clinical studies showed that the coronary wedge pressure is increased in the presence of collateral vessels, presumably as a consequence of a reduced collateral vascular resistance, resulting in a reduction of signs of ischemia during brief coronary occlusion ([3, 4, 6]). Our current understanding of the collateral circulation is limited, partly due to the lack of methods capable of expressing the development of the collateral vascular bed in terms of flow and resistance. The dynamic behavior of collateral vessels as seen angiographically before and during balloon coronary occlusion can be examined by blood flow velocity analysis in the contralateral donor coronary artery ([6, 7]). These studies demonstrated that a balloon coronary occlusion results in a transient 10% to 70% increase in coronary blood flow velocity in the contralateral artery when collateral vessels are present, although this phenomenon is marked in the absence of collateral vessels. Blood flow velocity changes in the ...
Conventional methods for qualitatively assessing human coronary collaterals include postmortem coronary angiography (5), patients history of a walking-through angina pectoris (30), nuclear cardiology techniques (31), recording of IC and surface ECG (19)and coronary wedge pressure (32)during PTCA and angiographic grading during vessel patency or occlusion (9). Positron emission tomography has been demonstrated to provide quantitative data of collateral flow to a vascular region of interest (31). However, this can be achieved only in the presence of a naturally occurring coronary artery occlusion of the ipsilateral vessel. The PTCA model for collateral assessment can be used in every patient with a stenotic lesion to be dilated. The presence of ECG ST-segment changes as a sign of myocardial ischemia is regarded to be quite sensitive in studies on collaterals (30). An ECG obtained during PTCA from an IC guidewire with its tip distal to the occluded stenosis can be used even more effectively. For ...
BACKGROUND AND PURPOSE: Current knowledge of the collateral circulation remains sparse, and a noninvasive method to better characterize the role of collaterals is desirable. The aim of our study was to investigate the presence and distal flow of collaterals by using a new MR perfusion territory imaging, vessel-encoded arterial spin-labeling (VE-ASL). MATERIALS AND METHODS: Fifty-six patients with internal carotid artery (ICA) or middle cerebral artery (MCA) stenosis were identified by sonography, VE-ASL was performed to assess the presence and function of collateral flow. The perfusion information was combined with VE maps into high signal-intensity-to-noise-ratio 3-colored maps of the left carotid, right carotid, and posterior circulation territories. The presence of the anterior and posterior collateral flow was demonstrated by the color of the standard anterior cerebral artery/MCA flow territory. The distal function of collateral flow was categorized as adequate (cerebral blood flow [CBF] >= ...
RESULTS: A total 269 patients were participated in the study population (55 in CIN(+) group, 214 in CIN(-) group). The blood creatinine levels were significantly higher in the CIN(+) group on the 48-72 hours following the coronary angiography. In the studied population, 70 out of 269 patients had a good CCC according the Rentrop classification (64 patients [30%] in the CIN(-) group, six patients [16%] in the CIN(+) group). The frequency of the well-developed coronary collaterals were significantly higher in the CIN(-) group ( ...
Background: We hypothesized that cerebral perfusion deficits are more severe in acute stroke patients with poor collaterals and that the severity would increase over time if reperfusion does not occur.. Methods: This is a substudy of DEFUSE 2. Collaterals were assessed on conventional angiography and dichotomized as poor vs. good flow. DWI and PWI were performed before and within 12 hrs after endovascular therapy; PWI lesion volumes were determined using a Tmax,6sec threshold. The hypoperfusion ratio (HR) was calculated by determining the proportion of the PWI lesion that had severe Tmax delay (,10sec). Acute lesion growth was defined as the difference between the baseline and follow-up DWI volume.. Part 1: In patients with an ICA or M1 occlusion we compared the HR to the collateral score. An ROC curve assessed whether the HR predicts the collateral score.. Part 2: Among patients who did not experience early reperfusion, the difference between the baseline and follow-up HR was assessed and ...
The extent of collateral circulation in 46 patients who had intracoronary thrombolysis within six hours of the onset of acute myocardial infarction was evaluated. Patients who had had a previous myocardial infarction (4 cases) or who had spontaneously recanalized infarct related coronary arteries (5 cases) were excluded from the analysis. Collateral development was graded during coronary cineangiography according to the extent of opacification of the collateral and epicardial arteries distal to the site of occlusion (collateral index 0 to 3). Angina was considered to be present before myocardial infarction if it had occurred more than one week before acute myocardial infarction. Collateral channels were visible in only two of 19 patients without angina before infarction and nine of the 18 patients with angina before infarction. The prevalence of angina and the collateral index were not significantly influenced by the extent of coronary vessel disease. It is concluded that myocardial ischaemia is ...
Rentrop et al. researched collateral filling of stenotic coronary artery during inflation of the PTA balloon. Contrast dye was injected as soon as the patient developed ST-T changes on ECG or angina, but no later than 90 seconds after inflation of the balloon.
The differences in the extent of collateral circulation among patients with seemingly similar clinical characteristics raise the possibility that genetic and molecular differences may play a role in collateral development. Because circulating monocytes are considered the key element in the development of collateral circulation, we set out to uncover novel transcriptional determinants of human coronary collateralization using a combination of established and newly developed microarray bioinformatics analysis techniques. The principal finding of this study is that the monocyte transcriptome of closely matched patients with CAD who possess abundant collateral circulation is significantly different from the transcriptome of collateral-poor CAD subjects. Interestingly, many of the observed changes in gene expression in this study parallel prior observations in a mouse model of hind-limb ischemia.37. The key differences include significant alterations in transcriptional regulation of specific ...
Background: Collateral grade on cerebral angiography has great predictive significance for patient outcome, which is important to determine indication for endovascular therapy in acute ischemic stroke (AIS). Distal hyperintense vessels (DHV) on fluid-attenuated inversion recovery imaging (FLAIR) is a noninvasive and useful imaging marker that reflects leptomeningeal collateral flow. We investigated whether DHV in patients with AIS was associated with collaterals grade on cerebral angiography and clinical outcome after endovascular therapy.. Methods: We retrospectively reviewed patients with AIS who had internal carotid artery or middle cerebral artery occlusion in three comprehensive stroke centers from August 2011 to July 2015. We selected those who underwent FLAIR sequence before endovascular therapy. Presence of DHV was evaluated using a previously-published method. Collateral grades on pre-treatment cerebral angiography were assessed with the American Society of Interventional and ...
Obesity is associated with impaired coronary collateral vessel development. Yilmaz, M.B.; Biyikoglu, S.F.; Akin, Y.; Guray, U.; Kisacik, H.L.; Korkmaz, S. // International Journal of Obesity & Related Metabolic Disorders;Dec2003, Vol. 27 Issue 12, p1541 BACKGROUND:: Chronic myocardial ischaemia due to coronary artery stenosis or occlusion has been shown to increase the growth of coronary collateral circulation. Collateralization leads to increased oxygen delivery to the area at risk and hence may reduce ischaemia, prevent infarction and... ...
We have demonstrated that in patients with AIS with terminal ICA or proximal MCA occlusions, the degree of collateral circulation on admission CTA correlates with the admission DWI lesion volume. Moreover, using a simple and reliable grading system, we have identified a malignant CTA collateral profile that is highly specific for patients with large baseline infarcts at high risk for poor long-term outcome. Our CTA collateral score of zero has ,95% specificity for admission DWI lesion volume ,100 mL and a ,90% rate of 3-month death or dependency. These findings are relevant for clinical practice because CTA is more widely available in the emergency setting than MR imaging-DWI. In addition, CTA collateral grading may provide a useful alternative for patients ineligible for MR imaging. Conventional angiography is the reference standard test for collateral evaluation because it incorporates the timing of collateral filling.16 However, its major drawbacks include its invasiveness and the time ...
Peripheral arterial disease (PAD) is a global problem - over 202 million people worldwide are estimated to have PAD. In the United States alone, PAD results in $21 billion in annual costs and is the leading cause of lower limb amputation. PAD arises when atherosclerotic plaques block arteries in the lower limbs, thereby limiting blood flow to the distal tissue. A promising therapeutic approach to restore distal blood flow is to stimulate the lumenal growth of the patients own pre-existing collateral arteries that bypass the occlusion(s) (i.e. arteriogenesis). Unfortunately, large clinical trials have had limited success to date, highlighting the critical need to better understand the basic mechanisms regulating arteriogenesis.. Arteriogenesis occurs in response to increased blood flow through the collateral arteries that bypass an occluded artery. We have recently demonstrated that arteriogenesis varies along collateral artery pathways due to differences in regional hemodynamics (Heuslein and ...
No. Wellens T-waves are always AFTER an episode of pain, and when no ECG was recorded DURING the pain. But we know from reperfusion trials that this is exactly the same kind of T-wave inversion we get after reperfusion. So, extrapolating backward in time, those who have Wellens had upright T-waves with ST elevation at the time of their pain. They had spontaneous reperfusion (which is very common in STEMI) and when the were pain free with open artery (or good collateral circulation), then the ECG was recorded and showed T-wave inversion. In Wellens study, all 180 patients had EITHER an open LAD or good collateral circulation to the anterior wall.. ReplyDelete ...
RESULTS: Factors associated with good outcome on univariable analysis were younger age, female sex, hypertension, diabetes mellitus, atrial fibrillation, small infarct core (ASPECTS ≥8), vessel recanalization, lower pre-tPA NIHSS scores, and good collaterals according to Tan methodology, ASPECTS methodology, and Miteff methodology. On multivariable logistic regression, only lower NIHSS scores (OR, 1.186 per point; 95% CI, 1.079-1.302; P = .001), recanalization (OR, 5.599; 95% CI, 1.560-20.010; P = .008), and good collaterals by the Miteff method (OR, 3.341; 95% CI, 1.203-5.099; P = .014) were independent predictors of good outcome. Poor collaterals by the Miteff system (OR, 2.592; 95% CI, 1.113-6.038; P = .027), Maas system (OR, 2.580; 95% CI, 1.075-6.187; P = .034), and ASPECTS method ≤5 points (OR, 2.685; 95% CI, 1.156-6.237; P = .022) were independent predictors of extremely poor outcomes. ...
The human coronary circulation is not an end-arterial system. Coronary collateral circulation has been shown to have a significant protective
Our ability to link amplified arteriogenesis to a unique hemodynamic stimulus (ie, reversed flow with increase shear stress magnitude) was facilitated by the development of a LSF approach for mouse hindlimb collaterals.18 We developed that approach because, despite the known importance of hemodynamic stimuli in driving collateral development, there was a surprising lack of quantitative data on the hemodynamic changes within these arteries. This is likely because both the small size of the arteries (,100 μm) and the fact that different surgical models elicit arteriogenesis along different collateral pathways.2 Using LSF,18 we determined the occurrence of at least 3 distinct hemodynamic conditions in these collateral vessels: a nonreversed increase in shear stress near the feeding entrance to the collateral loop, an increase in shear stress from low/oscillating flow to sustained high shear stress at the central anastomotic region, and an increase in shear stress but in a reversed direction at the ...
Clinical outcome after mechanical thrombectomy (MT) for large vessel occlusion (LVO) stroke is influenced by the intracerebral collateral status. We tested the hypothesis that patients with preexisting ipsilateral extracranial carotid artery stenosis (CAS) would have a better collateral status compared to non-CAS patients. Additionally, we evaluated MT-related adverse events and outcome for both groups.Over a 7-year period, we identified all consecutive anterior circulation MT patients (excluding extracranial carotid artery occlusion and dissection). Patients were grouped into those with CAS ≥ 50% according to the NASCET criteria and those without significant carotid stenosis (non-CAS). Collateral status was rated on pre-treatment CT- or MR-angiography according to the Tan Score. Furthermore, we assessed postinterventional infarct size, adverse events and functional outcome at 90 days.We studied 281 LVO stroke patients, comprising 46 (16.4%) with underlying CAS ≥ 50%. Compared to non-CAS ...
Methods and Results-We screened for signaling components that are activated in response to administration of FGF-2 to cultured vascular smooth muscle cells (VSMCs) and detected a significant increase of Rap2 but not of other Ras family members, which corresponded to a strong upregulation of Rap2 and C-Raf in growing collaterals from rabbits with femoral artery occlusion. Small interfering RNAs directed against Rap2 did not affect FGF-2 induced proliferation of VSMC but strongly inhibited their migration. Inhibition of FGF receptor-1 (FGFR1) signaling by infusion of a sulfonic acid polymer or infection with a dominant-negative FGFR1 adenovirus inhibited Rap2 upregulation and collateral vessel growth. Similarly, expression of dominant-negative Rap2 blocked arteriogenesis, whereas constitutive active Rap2 enhanced collateral vessel growth.. ...
Results and Discussion: Receiver Operating Characteristics demonstrated no improvement using frequency dependant impedance compared to the constant part of the collateral impedance. The functional parameters aCon and cIMP were better than the total blood flow for the characterization of collateral function. The collateral function improved significantly during occlusion time (aCON in one= 0.20+/-0.17, two=0.22+/-0.25, three and more month= 0.28+/-0.18 cm*s-1*mmHg-1). A predominant systolic, diastolic or combined collateral flow profile was not correlated to the collateral function. Considering the anatomic location of Levin 17 patients had one, 15 two and 24 three different collateral pathways. In the majority of cases (63 of 91 patients) a septal pathway was included. In all patients the comparison of the Rentrop grading, the anatomic location classification and the collateral connection grading showed only for the latter an independent and significant relation with the collateral function. In ...
Collateral blood flow plays a pivotal role in steno-occlusive internal carotid artery (ICA) disease to prevent irreversible ischaemic damage. Our aim was to investigate the effect of carotid artery disease upon cerebral perfusion and cerebrovascular reactivity and whether haemodynamic impairment is influenced at brain tissue level by the existence of primary and/or secondary collateral. Eighty-eight patients with steno-occlusive ICA disease and 29 healthy controls underwent MR examination. The presence of collaterals was determined with time-of-flight, two-dimensional phase contrast MRA and territorial arterial spin labeling (ASL) imaging. Cerebral blood flow and cerebrovascular reactivity were assessed with ASL before and after acetazolamide. Cerebral haemodynamics were normal in asymptomatic ICA stenosis patients, as opposed to patients with ICA occlusion, in whom the haemodynamics in both hemispheres were compromised. Haemodynamic impairment in the affected brain region was always present in
We previously showed that prompt reperfusion and angiographic collateral vessels may impact myocardial salvage and infarct transmural extent among patients with an occluded IRA. In the current investigation, we found that in addition to time to reperfusion and collateral vessels, the angiographic area at risk and the initial TIMI flow grade at the time of PCI are independent predictors of myocardial salvage by multivariate analysis. The novel index of myocardial salvage described here compares favorably with infarct transmurality to predict wall motion recovery after an acute STEMI.. Previous experimental studies have shown that the final infarct size closely correlates with the mass of jeopardized myocardium within the territory of the IRA (9). It is known that reperfusion of an occluded artery results in greater improvement in regional LV function when collateral vessels are present in the acute phase of myocardial infarction (10). However, the adjunctive effect that collateral flow might have ...
CONTRAST-ENHANCED CARDIAC COMPUTED TOMOGRAPHY (CT) is being increasingly used for the investigation of patients with suspected coronary artery disease. Recent technological developments have allowed the reliable diagnosis of both coronary stenosis and occlusion with this modality. In addition to the identification of luminal stenosis, CT has the potential to visualize coronary plaque, collateral circulation, myocardium, and left ventricular function. Although the typical CT appearance of chronic coronary occlusion (extensive calcification and negative remodeling within the artery, potential presence of collateral coronary circulation and, in most cases, impaired left ventricular function associated with thinned myocardium) is well known, characteristics of acute occlusion have not been well described. The distinction between acute and chronic coronary occlusion has particular importance for the management of patients presenting with acute chest pain. In this series of cases, we highlight some ...
OBJECTIVES. The aim of this study was to evaluate myocardial blood flow regulation in collateral-dependent myocardium of patients with coronary artery disease. BACKGROUND. Despite great clinical relevance, perfusion correlates of collateral circulation in humans have rarely been estimated by quantitative methods at rest and during stress. METHODS. Nineteen patients with angina and isolated occlusion of the left anterior descending (n = 14) or left circumflex (n = 5) coronary artery were evaluated. Using positron emission tomography and nitrogen-13 ammonia, we obtained flow measurements at baseline, during atrial pacing-induced tachycardia and after intravenous administration of dipyridamole (0.56 mg/kg body weight over 4 min). Flow values in collateral-dependent and remote areas were compared with values in 13 normal subjects. RESULTS. Flow at rest was similar in collateralized and remote myocardium (0.61 +/- 0.11 vs. 0.63 +/- 0.17 ml/min per g, mean +/- 1 SD), and both values were lower than ...
INTRODUCTION Stimulation of coronary collateral vessel growth by therapeutic angiogenesis (TA) offers an alternative treatment option for patients with refractory angina. Several TA modalities, including delivery to the heart of angiogenic growth factors (proteins or genes) and cells have been tested in clinical trials in the past two decades, but so far none of them resulted in significant therapeutic efficacy in large scale studies. This review attempts to identify the main obstacles hindering clinical success and recommends measures to overcome them in the future. AREAS COVERED After stating the medical need and rational for TA, and listing and briefly discussing past and current TA clinical trials, three main areas of obstacles are described: conceptual questions, technical limitations and clinical design uncertainties. Based on scientific and technical advances and lessons learned in past clinical trials, potential solutions to overcome some of these obstacles are proposed. EXPERT OPINION
A collateralized debt obligation is an investment that is backed by a collection of several different assets. While collateralized...
In stroke due to middle cerebral artery (MCA) occlusion, collaterals may sustain tissue in the peripheral MCA territory, extending the time window for recanalizing therapies. However, MCA occlusions often block some or all of the lenticulostriate (LS) arteries originating from the M1 segment, eliminating blood flow to dependent territories in the striatum, which have no collateral supply. This study examines whether mechanical thrombectomy (MTE) can avert imminent striatal infarction in patients with acute MCA occlusion.279 patients with isolated MCA occlusion subjected to MTE were included. Actual LS occlusions and infarctions were assigned to predefined LS occlusion and LS infarct patterns derived from known LS vascular anatomy. The predictive performance of LS occlusion patterns regarding ensuing infarction in striatal subterritories was assessed by standard statistical measures.LS occlusion patterns predicted infarction in associated striatal subterritories with a positive predictive ...
OBJECTIVE: Elevated mean platelet volume (MPV) has been proposed as a risk factor for coronary artery disease (CAD) and is associated with poor clinical outcome in acute coronary syndrome (ACS). We aimed to evaluate the association of MPV with presence of coronary collateral vessel (CCV) in patients with ACS.. METHODS: A total of 417 patients with ACS were included in the study. All patients underwent coronary angiography on the first day after admission and patients with a greater than or equal to 80% obstruction in at least one epicardial coronary artery were included in the study. The CCVs are graded according to the Rentrop scoring system and a Rentrop grade 0 was accepted as no CCV development (group 1), Rentrop grade 1-2-3 were accepted as presence of CCV development (group 2).. RESULTS: The median of MPV was 9.1±1.4fl. Mean age was 60±12 year. Group 1 consisted of 233 (55.9%) patients and Group 2 consisted of 184 (44.1%) patients. Presence of CCV was significantly associated with high ...
BACKGROUND AND PURPOSE: Blood supply through collateral pathways improves regional cerebral blood flow and may protect against ischemic events. The effect of collaterals on the risk of stroke and transient ischemic attack (TIA), in the presence of angiographic severe internal carotid artery (ICA) stenosis, was assessed. METHODS: Angiographic collateral filling through anterior communicating and posterior communicating arteries and retrograde filling through ophthalmic arteries were determined in all patients at entry into the North American Symptomatic Carotid Endarterectomy Trial. Kaplan-Meier event-free survival analyses were performed on 339 medically treated and 342 surgically treated patients. RESULTS: The presence of collaterals supplying the symptomatic ICA increased with severity of stenosis. Two-year risk of hemispheric stroke in medically treated patients with severe ICA stenosis was reduced in the presence of collaterals: 27.8% to 11.3% (P=0.005). Similar reductions were observed for
Aneurysm surgery: optic nerve often displaced superiorly by aneurysm, vs. falciform ligament (sharp tethering edge). Early opening of optic canal & falciform ligament to free optic nerve --, decrease risk of visual deficit. If clipped, orbit dependent on collateral supply from ECA (maxillary, facial arteries ...
This report studies the Global Collateralized Debt Obligation Market, analyzes and researches the Collateralized Debt Obligation development status and...
Decreased collateral vessel formation in the diabetic peripheral limbs is characterised by abnormalities of the angiogenic response to ischemia. Hyperglycemia is known to activate protein kinase C (PKC) affecting the expression and activity of growth factors such as VEGF and PDGF. The present study investigates the role of PKCδ in diabetes-induced poor collateral vessel formation and inhibition of angiogenic factors expression and actions. Ischemic adductors muscles of diabetic Prkcd+/+ mice exhibited reduced blood reperfusion, vascular density and number of small vessels as compared to non-diabetic Prkcd+/+ mice. By contrast, diabetic Prkcd-/- mice showed significant increased blood flow, capillary density and number of capillaries. Although expression of various PKC isoforms were unchanged, activation of PKCδ was increased in diabetic Prkcd+/+ mice. VEGF and PDGF mRNA and protein expression were decreased in muscles of diabetic Prkcd+/+ mice and normalized in diabetic Prkcd-/- mice. ...
There is intense controversy as to the mechanisms underlying chronic but reversible left ventricular (LV) ischemic dysfunction. The aim of this study was to investigate the physiology underlying this condition in a canine model of noninfarcted collateral-dependent myocardium. METHODS: Six mongrel dogs were instrumented with ameroid constrictors on the left circumflex and right coronary arteries and a partial occluder on the left anterior descending coronary artery. The animals were followed up for 6 mo. Every 6 wk, measurements of regional wall thickening (M-mode echo), myocardial blood flow ((13)N-ammonia PET), oxygen consumption ((11)C-acetate PET), and glucose uptake ((18)F-FDG PET) were obtained. After 6 mo, myocardial blood flow reserve (during adenosine infusion) and regional contractile reserve (during infusion of a low dose of dobutamine) were also investigated. RESULTS: Following ameroid implantation, regional thickening decreased in the posterior wall (to 34% +/- 13% of baseline; P , ...
Natural adaptation to femoral artery occlusion in animals by collateral artery growth restores only approximately 35% of adenosine-recruitable maximal conductance (C(max)) probably because initially elevated fluid shear stress (FSS) quickly normalize
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Looking for online definition of collateral bundle in the Medical Dictionary? collateral bundle explanation free. What is collateral bundle? Meaning of collateral bundle medical term. What does collateral bundle mean?
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Many collateral adjectives enter the language because English regularly substitutes attributive use of the noun itself (or of a verbal noun from a related verb) for use of an adjective, so true adjectives are often missing. Adjectives are then borrowed from Greek or Latin for technical and academic usage, where true adjectives are preferred over attributive use of nouns. Because of this, collateral adjectives tend to be more technical or academic in tone than their corresponding nouns. Some collateral adjectives have a related noun which may be a near synonym for the noun in question. For example, one adjective for business is commercial, which also has a cognate noun commerce. Because there is no one-to-one correspondence between adjective and noun in English, and there is no regular derivation that they upset, they are not actually suppletive. Some nouns have both collateral and derived adjectives. For example, for the noun father there is derived fatherly alongside collateral paternal, and ...
This CLE course will provide counsel with an understanding of the scope and application of Section 506(c) allowing the debtor or trustee to recover from the secured lender costs and expenses of preserving/disposing of the estates asset. The panel will explain surcharge on collateral, the debtors burden under 506(c) and recent case law, and outline best practices for secured lenders to defeat a surcharge motion.
Toronto-based GDA Group, a North American digital assets firm specializing in capital advisory and trading services to institutional investors, announced the launch of GDA Lending. The new service will provide investors with access to non-recourse lending for USD, BTC, ETH, EOS and XRP at up to 65% loan-to-value ratio.. GDA Lending joins the ranks of other crypto lending institutions such as BlockFi, Nexo and DrawBridge Lending (recently acquired by Galaxy), which offer collateralized lending to its clients. Bitcoin golden physical coin illustration on Euro banknotes of 20 and 50 euros. visual … [+] representations of the digital Cryptocurrency Bitcoin with the Euro bill. Bitcoin is a popular digital currency that showed growth and is widely spread, accepted from banks, markets and other services and shops as ways of payments. The exchange rate today for 1 bitcoin blockchain is 9969 euros. Thessaloniki, Greece - August 8, 2020 (Photo by Nicolas Economou/NurPhoto via Getty ...
Hemorrhage: Trans-Arterial Embolization for Hemorrhage or Vascular Malformations. Veterinary patients occasionally suffer from hypovolemic shock secondary to severe hemorrhage from a number of different causes including neoplasia, coagulopathy, GI ulceration, and trauma. In the majority of cases, standard medical and surgical procedures can be used to stabilize these often severely debilitated animals. Occasionally, standard therapies fail and alternatives are necessary.. For example, severe epistaxis can typically be managed conservatively. However, once intractable, few options remain. Carotid ligation can be performed and although this may temporize bleeding, once collateral blood supply develops bleeding may resume and no further treatment options exist. This is an especially important consideration when the underlying cause of epistaxis persists because the patient remains at risk for bleeding. An alternative to carotid ligation that permits repeated treatments if necessary is ...
TY - JOUR. T1 - MR Perfusion to Determine the Status of Collaterals in Patients with Acute Ischemic Stroke. T2 - A Look Beyond Time Maps. AU - Nael, Kambiz. AU - Doshi, A.. AU - De Leacy, R.. AU - Puig, J.. AU - Castellanos, M.. AU - Bederson, J.. AU - Naidich, T. P.. AU - Mocco, J.. AU - Wintermark, M.. PY - 2018/2/1. Y1 - 2018/2/1. N2 - BACKGROUND AND PURPOSE: Patients with acute stroke with robust collateral flow have better clinical outcomes and may benefit from endovascular treatment throughout an extended time window. Using a multiparametric approach, we aimed to identify MR perfusion parameters that can represent the extent of collaterals, approximating DSA. MATERIALS AND METHODS: Patients with anterior circulation proximal arterial occlusion who had baseline MR perfusion and DSA were evaluated. The volume of arterial tissue delay (ATD) at thresholds of 2- 6 seconds (ATD2- 6seconds) and 6 seconds (ATD6seconds) in addition to corresponding values of normalized CBV and CBF was calculated ...
Arteriogenesis, the adaptive outward growth of pre-existing collateral arteries, is the most efficient endogenous rescue mechanisms in vertebrates against the occlusion of a major artery (biological bypass). Here, collateral growth was induced using the first model for cerebral arteriogenesis, the 3-vessel occlusion (3-VO) rat model. (I) 3-VO resulted in a significant diameter increase within 7 days in the posterior cerebral artery (PCA) and posterior communicating artery (Pcom), classifying the region of interest. Immunhistological staining demonstrated proliferative activation and macrophage invasion, already 24h post 3-VO within the PCA, confirming the arteriogenic phenotype. Furthermore, activation of the PCA endothelium was detected within 3 days post 3-VO by scanning electron microscopy. (II) For analysing the molecular mechanism of cerebral arteriogenesis, collateral tissue from the growing PCA was selectively isolated. Here, 24h post 3-VO 164 genes were detected to be significantly ...
Tim unlocks opportunities for wealth creation for Black, rural entrepreneurs by shifting our current economic development approach away from an overemphasis on collateral and prior wealth, and towards an appreciation of peer support and community prosperity.
Lee CW, Stabile E, Kinnaird T, Shou M, Devaney JM, Epstein SE, Burnett MS. Temporal patterns of gene expression after acute hindlimb ischemia in mice: insights into the genomic program for collateral vessel development. J Am Coll Cardiol. 2004 Feb 04; 43(3):474-82 ...
To date, regenerative laboratories have attempted to engineer only a few whole organs. This endeavor requires engineering not only the organ but also vascular tissues to maintain a healthy organ with full functionality. We concentrated our initial efforts on developing the microvasculature and systemic support in the BEL and found that collateral systemic circulation developed in all animals that survived 2 weeks or longer. Because BEL was supplied with oxygenated rather than deoxygenated blood, we were unable to assess gas exchange due to a lack of an oxygen gradient at the alveolar capillary junction.. GE related to angiogenesis and lung tissue development indicated that tissue development was still in progress 1 month after transplantation. Histological examination of tissues indicated that collateral circulation developed in all animals as early as 2 weeks after transplant. Histological evaluation showed progression in lung and airway epithelial cell development with an associated increase ...
A method of delivering an arteriogenic factor. The factor is delivered in a medically effective manner to structurally enlarge an existing blood vessel. A distal portion of a catheter can be advanced to an existing blood vessel to deliver the arteriogenic factor.
Collateral sprouting of axons in the pe-ripheral nervous system is a branching out-growth of new axon terminals from non-injured axons into adjacent denervated regions of tar-get tissue. The initiation of collateral sprouting is probably triggered by the interaction between the factors released by degenerated neural pathways or denervated target tissue, and pu-tative interaction between the injured and non-injured neurons within a dorsal root ganglion (transneuronal mechanism). Sprouting of axons along the neurilemmal tubes of Schwann cells was investigated by an end-to-side anastomo-sis of a peroneal nerve segment to the intact su-ral nerve on the hind limb of the rat. In group A, the peroneal nerve segment from the contrala-teral limb was attached to the sural nerve. No-ne of the nerves on the side of the anastomosis were injured. In group B, the same procedure was used as in group A. In addition, dorso-cutaneous nerves from the L4-L6 spinal segments were cut. Injured neurons were therefore ...
Formats for Collaterals: The formats, as per NSE Clearing, that are required for submission of documents for Trading Members operating in the Capital Market Segment. Know more about Formats for Collaterals Today, visit NSE India.
Unbound Finance operates a so-called liquidation-free collateralization platform, which, because the identify suggests, permits customers to acquire interest-free loans in opposition to collateralized tokens. Automated market makers are DeFis Zero to One Innovation and were constructing the aggregator layer to allow higher yields [and] capital effectivity for our customers, stated Tarun Jaswani, CEO and Founding father of Unbound Finance. There are some severe backers behind Unbound Finances $5.8 million elevate. Along with Pantera Capital and Michael Arringtons XRP Capital, the mission acquired direct funding from Hashed, Coin98 Ventures, LedgerPrime, CMS Holdings and lots of others. Over a dozen angel buyers additionally participated within the elevate, together with the founders of Angelist, Enjin, Gnosis, Kyber Community, Polygon, Concord, Polkastarter and others. Pantera CEO Dan Morehead commented on the affect Unbound Finance may have on the budding DeFi business:. ...
An arterial exam looks at the arteries in the body. Arteries carry blood to cells and organs. An upper extremity arterial evaluation examines blood flow in the arms and a lower extremity arterial evaluation examines arteries in the legs. Normally the inner wall of the arteries is smooth. When the inner lining becomes hard and thick, atherosclerosis (hardening of the arteries) develops. This can cause an artery to narrow (called a stenosis) or close off completely (called an occlusion). When this happens, blood must go through other blood vessels to get around the blockage causing alternate circulation called collateral circulation. Atherosclerosis occurs in all arteries to some degree however the arteries of the neck, heart and legs are most commonly affected. Peripheral Arterial Disease (PAD) refers to the blockages in the arms or legs.. An arterial evaluation is done to examine the arteries in the arms or legs to look at the blood flow to locate stenosis or occlusion.. An arterial ...
An arterial exam looks at the arteries in the body. Arteries carry blood to cells and organs. An upper extremity arterial evaluation examines blood flow in the arms and a lower extremity arterial evaluation examines arteries in the legs. Normally the inner wall of the arteries is smooth. When the inner lining becomes hard and thick, atherosclerosis (hardening of the arteries) develops. This can cause an artery to narrow (called a stenosis) or close off completely (called an occlusion). When this happens, blood must go through other blood vessels to get around the blockage causing alternate circulation called collateral circulation. Atherosclerosis occurs in all arteries to some degree however the arteries of the neck, heart and legs are most commonly affected. Peripheral Arterial Disease (PAD) refers to the blockages in the arms or legs.. An arterial evaluation is done to examine the arteries in the arms or legs to look at the blood flow to locate stenosis or occlusion.. An arterial ...
There is evidence of lateral STEMI with hyperacute T-waves in V5 and V6 and I and aVL. So this is consistent with circumflex occlusion. However, it is common for circ occlusions to show little on the ECG, at least in the literature. My experience is that there is nearly always evidence of it to an expert reader with a discerning eye. As for V1, RV involvement only happens with RCA ACS: with a proximal occlusion in which the RV does not get collateral circulation from the LAD, there can be RV STEMI with ST elevation in V1. These certainly can cause hypotension. In this case, the hypotension was due to poor LV function from LAD STEMI.. Delete ...
In the matter of section 156 of the Property Law Act 2007 and in the matter of the mortgage over goods (a specific security deed dated December 2015 and a Commercial Loan Facility dated 19 February 2020) over the following charged goods:. 2015 Mercedes-Benz Actros 3260/L48 Truck Registration No. JKL468 VIN WDB9302442L937339;. 2008 DAF XF 105 Truck Registration No. NKY163 VIN XLRAD47MS0E819110; and. 2020 Fruehauf RBC 5 axle trailer Registration No. 56G43 VIN 7A9RBC5SX0F007417. (collateral). Notice is hereby given that on 15 July 2021 Heartland Bank Limited entered into possession of the collateral.. Communications regarding the collateral may be addressed to Anthony Harper, PO Box 2646, Christchurch.. C. R. VINNELL, Solicitor for the Mortgagee.. ...
shows. The primary purpose of this device is to find out what processes are going on in our head at the moment. Assign a study of after a serious headache to prevent hemorrhage. The second useful action of REG is that determines the blood flow through the main, main vessels and the collateral circulation of the , that is, the flow of blood currents bypassing the main vessels, if for any reason they can not cope with their work. Before the invention of rheoencephalography, such ailments as neurocirculatory dystonia and migraine and diseases were not considered. To prove them from a medical point of view is almost impossible. A person is considered healthy. The organs function normally, which means that the person writhing with a headache,( and men are sick of migraines, too!) Is likely to be feigning. After all, amazingly, from the headache these people are helped only by those means that contain caffeine. And only the study REG regrouped everything in its place. She proved their presence in a ...
Depends: It depends if the vessel is an artery or a vein, the size of the vessel, collateral circulation, co-existing illnesses etc. Blood clot in a vein can travel to lung and cause lung infarction. Clot in an artery may damage the tissue/organ supplied by that artery. Heart attack is one example of clot in an artery. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more ...
The Arteriograph is a diagnostic instrument which is able to measure the severity of arteriosclerosis. This is the condition of arterial blockage caused by inflammation or damage within arteries followed by an over production of a compound known as plaque created by the body to repair the damage. Plaque is made up of cholesterol, minerals such as calcium, specialised red blood cells known as platelets and other clotting factors. The Arteriograph is a simple and painless, non invasive investigation that can diagnose arteriosclerosis at an early stage . Symptoms of arterial blockage include chest pain from blocking heart arteries, or the loss of sensation, numbness, or cramp in the lower limbs as the leg arteries block. These symptoms tend not to occur until a considerable amount of an artery is blocked and other arteries are no longer able to offer effective collateral circulation. Symptoms of cardiovascular disease leading to heart attacks and strokes usually appear only in the last and late ...
Each monthly episode will discuss recent publications in the fields of genomics and precision medicine of cardiovascular disease.
Annual precipitation in the largely agricultural South-Central United States is characterized by a primary wet season in May and June, a mid-summer dry period in July and August, and a second precipit
The Mammalian Phenotype (MP) Ontology is a community effort to provide standard terms for annotating phenotypic data. You can use this browser to view terms, definitions, and term relationships in a hierarchical display. Links to summary annotated phenotype data at MGI are provided in Term Detail reports.
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Citi, Hong Kong, Hong Kong, Hong Kong job: Apply for Cash and Collateral Management Assistant Vice President in Citi, Hong Kong, Hong Kong, Hong Kong. Operations jobs available with eFinancialCareers.
NEW YORK - J.P. Morgan today announced that its Projections & Simulations service is now available globally. Part of the Securities Collateral Management product, Projections & Simulations provides se...
15th Annual Collateral Management Forum, Oct 2021 (Not Final), Amsterdam, Netherlands, organized by Fleming.. Find conference details | CLocate
Collateral Damage - StarCraft II - Legacy of the Void: A Short Story By: MATT BURNS A crowd stands outside the safe house on Anselm, the people shifting and jostling and craning their necks for a chance...
Liebeskind DS (September 2003). "Collateral circulation". Stroke. 34 (9): 2279-2284. doi:10.1161/01.STR.0000086465.41263.06. ... as the bilateral circulation continues perfusing the brain. Thrombus formation is the natural physiologic response to the ...
This is known as collateral circulation. The saphenous nerve is a branch of the femoral nerve that runs with the great ... Removal of the saphenous vein will not hinder normal circulation in the leg. The blood that previously flowed through the ... a clot fragment can migrate to the deep venous system and to the pulmonary circulation. Also it can be associated with, or ...
with A. Morgan Jones: Bramwell, C.; Jones, A. M. (October 1941). "Coarctation of the aorta: the collateral circulation". Br. ... and to the features of the circulation in athletes are well known. J. Crighton Bramwell's father Byrom Bramwell and eldest ...
"The collateral arterial circulation in the pelvis. An angiographic study". American Journal of Roentgenology. 102 (2): 392-400 ...
Leptomeningeal collateral circulation Moore KL, Dalley AR. Clinically Oriented Anatomy, 4th Ed., Lippincott Williams & Wilkins ...
The radial artery is also used to evaluate the collateral circulation of blood through the hands; applying pressure through ... adequate collateral circulation can be ascertained by how quickly normal colour returns after the pressure is removed. The ... "Evaluation of collateral circulation of the hand". Journal of Clinical Monitoring. 8 (1): 28-32. doi:10.1007/BF01618084. ISSN ... It travels superiorly to anastomose with the radial collateral artery around the elbow joint Palmar carpal branch of radial ...
... so there is potential for collateral circulation here. The venous drainage of the duodenum follows the arteries. Ultimately ...
"The clinical significance of the pulmonary collateral circulation". Circulation. American Heart Association. 24 (3): 677-690. ... Largely for this reason, bronchial artery circulation is usually sacrificed during lung transplants, instead relying on the ... persistence of a microcirculation (presumably arising from the deoxygenated pulmonary circulation) to provide perfusion to the ...
The result may be the development of collateral circulation. Tetralogy of Fallot (ToF) Total anomalous pulmonary venous ... Mathematical models are used to address the issue of pressure level alterations of circulation after the procedures. The ... or a mixture of oxygenated and unoxygenated blood entering the systemic circulation. It is caused by structural defects of the ... and these models permit clear analyses of the pressure increase allowing doctors to avoid possible venous circulation ...
Stead, SW; Stirt, JA (1985). "Assessment of digital blood flow and palmar collateral circulation". Journal of Clinical ... Allen's test looks for abnormal circulation. If color returns quickly as described above, Allen's test is considered to ... demonstrate normal circulation. If the pallor persists for some time after the patient opens their fingers, this suggests a ...
Collateral circulation gives "tree root" or "spider leg" appearance. Angiograms may also show occlusions (blockages) or ... The main symptom is pain in the affected areas, at rest and while walking (claudication). The impaired circulation increases ... The king's doctors prescribed complete rest and electric treatment to stimulate circulation, but as they were either unaware of ... Piazza G, Creager MA (April 2010). "Thromboangiitis obliterans". Circulation. 121 (16): 1858-61. doi:10.1161/CIRCULATIONAHA. ...
"Stimulation of the coronary collateral circulation by lidoflazine (R 7904)". Naunyn-Schmiedebergs Archiv für Experimentelle ...
There is no collateral circulation present besides the end arteries. Examples of an end artery include the splenic artery that ... The results are severe because the blood flow to that region is completely stopped since there is no collateral circulation. ...
... Cerebral circulation Leptomeningeal collateral circulation Fenrich, Matija; Habjanovic, Karlo ... for collateral circulation in the cerebral circulation. If one part of the circle becomes blocked or narrowed (stenosed) or one ... "Transcranial Doppler ultrasonography of carotid-basilar collateral circulation in subclavian steal". Stroke. 19 (8): 1036-1042 ... The circle of Willis is a part of the cerebral circulation and is composed of the following arteries: Anterior cerebral artery ...
"Transcranial Doppler ultrasonography of carotid-basilar collateral circulation in subclavian steal". Stroke. 19 (8): 1036-42. ... Classically, SSS is a consequence of a redundancy in the circulation of the brain and the flow of blood. SSS results when the ... Lord R, Adar R, Stein R (1969). "Contribution of the circle of Willis to the subclavian steal syndrome". Circulation. 40 (6): ... This is because of collateral vessels.[citation needed] As in vertebral-subclavian steal, coronary-subclavian steal may occur ...
There is usually collateral circulation between the superior and inferior orbital veins. The blood-vessels of the eyeball ( ...
Schaper W, The collateral circulation of the heart, New York, N.Y.: Elsevier, 1971. Kolibash AJ, et al., "Coronary collateral ... Cohen M and KP Rentrop, et al., "Limitation of myocardial ischemia by collateral circulation during sudden controlled coronary ... Fujita M, "Importance of angina for development of collateral circulation," British Heart Journal 1987; 57: 139-43. (Articles ... collateral circulation, and, in any case, sometimes precedes, and often prevents, infarction by relieving the critically ...
The patients having a significant collateral circulation can live to adulthood in rare cases; their circulation is often not ... Because the pressure in RCA exceeds the pressure in LCA a collateral circulation will increase. This situation ultimately can ... The development of symptoms in ALCAPA depends heavily on the amount of collaterals development. When only few collaterals are ... By the time of birth, the pressure will decrease in the pulmonic artery and the child will have a postnatal circulation. The ...
... the fine collateral circulation that it supplies is obliterated. Patients often survive on the collateral circulation from the ... A collateral circulation develops around the blocked vessels to compensate for the blockage, but the collateral vessels are ... This is also the case when the arterial constriction and collateral circulation are bilateral. Moyamoya syndrome is unilateral ... The arteries are either sewn directly into the brain circulation, or placed on the surface of the brain to reestablish new ...
... providing a collateral circulation. This collateral circulation allows for blood to continue circulating if the subclavian is ...
He pioneered the field of vascular surgery and noted collateral circulation following ligation of arteries. Porta was born in ...
Pulsatile back-bleeding from distal innominate artery stump should be checked to insure collateral circulation. In patients ... Innominate artery ligation leaves the carotid and subclavian circulations intact. ... and the carotid artery or the opposite carotid artery and the subclavian artery may be performed to restore normal circulation ...
This means that collateral circulation develops in the lower esophagus, abdominal wall, stomach, and rectum. The small blood ...
The genicular anastomosis provides collateral circulation to supply the leg when the knee is fully flexed. When the knee ...
Symptoms from poor blood circulation in the arm is uncommon due to collateral circulation in the arm. Young adults without risk ...
In these cases, the supply may be divided, some vessels sacrificed with expectation of adequate collateral circulation. In the ...
In the case of non-bronchial arteries, it is empirically known that some collateral circulations also develop. In addition, ... It is presumed that this is because the pulmonary circulation is dually controlled by the bronchial artery and the pulmonary ... of the Hemoptysis and Pulmonary Circulation Center, Kishiwada Rehabilitation Hospital, demonstrated for the first time in the ... and The National Hospital Organization Tokyo Hospital Pulmonary Circulation and Hemoptysis Center (Tokyo Hp) ; the top two ...
This selective sparing is due to the collateral circulation offered to macular tracts by the middle cerebral artery. ...
However, it takes time for sufficient collateral circulation to develop, making affected areas more vulnerable for sudden ... Individuals with arterial thrombosis or embolism often develop collateral circulation to compensate for the loss of arterial ...
Due to extensive collateral circulation, a coronary thrombus does not necessarily cause tissue death and may be asymptomatic.[ ... A large thrombus here slows overall blood circulation to heart tissue as well as may mechanically compress a coronary artery. ... Skyschally, Andreas; Erbel, Raimund; Heusch, Gerd (April 2003). "Coronary microembolization". Circulation Journal. 67 (4): 279- ... Circulation. 115 (8): 1051-8. doi:10.1161/CIRCULATIONAHA.106.675934. PMID 17325255. Borovac, Josip Anđelo; D'Amario, Domenico; ...
... or use their land as collateral for loans.[5] In one village, once the commune was operational the Party boss and his ... Dual circulation. *Go Out policy. *Made in China 2025. *Youth Business China ...
"Circulation. 126 (24): 2890-2909. doi:10.1161/CIR.0b013e318276fbcb. ISSN 0009-7322. PMID 23159553. S2CID 45644292.. ... Regular exercise for those with claudication helps open up alternative small vessels (collateral flow) and the limitation in ... "Circulation. 135 (12): e686-e725. doi:10.1161/CIR.0000000000000470. PMC 5479414. PMID 27840332.. ... Surgical treatment of peripheral circulation disorders)". Helvetica Chirurgica Acta (in German). 21 (5/6): 499-533. PMID ...
The popularity of the Brocock range was such that, by 2002, estimates put the number of air cartridge guns in circulation ... In addition, the spring often has unpredictable collateral transverse vibrations as well as torquing, both of which can cause ...
... an official Collateral Event of the 2019 Venice Biennale, which ran at Chiesa delle Penitenti, Venice from May to November 2019 ... Total circulation. (2020). 20,000. First issue. 2000. Country. United States. Based in. Brooklyn. ...
Circulation of money rocketed, and soon banknotes were being overprinted to a thousand times their nominal value and every town ... banks and the German government in which the American banks lent money to German banks with German assets as collateral to help ...
This selective sparing is due to the collateral circulation offered to macular tracts by the middle cerebral artery.[15] ...
... you allow more oxygen to perfuse the heart and ultimately generate more collateral circulation without actually increasing the ... One theory is that ECP exposes the coronary circulation to increased shear stress, and that this results in the production of a ...
It said that there were $5.1 billion worth of FTT tokens in circulation, and that Alameda's balance sheet held $3.66 billion of ... adding that all cryptocurrency exchanges should avoid using FTT tokens as collateral.[61][62] He also wrote that he expected ... "unlocked FTT", $2.16 billion of "FTT collateral", and $292 million of "locked FTT".[15] In the weeks immediately preceding the ...
... huge collateral damage all throughout the country ... and yet you're still seeing some of the same folks who acted ... here are no conservative or reactionary ideas in circulation".[108] ...
Circulation. 95 (4): 805-808. doi:10.1161/01.CIR.95.4.805. PMID 9054734. Retrieved 2009-06-10. "Micro-angiography for tumor ... "Use of Synchrotron Radiation Microangiography to Assess Development of Small Collateral Arteries in a Rat Model of Hindlimb ... uses monochromatic synchrotron radiation and a high-definition video system to provide an image of small collateral arteries ...
... injury Medial collateral ligament (MCL) injury Lateral collateral ligament (LCL) injury Superior Tibiofibular Joint Sprain - ... However, compression should not impede circulation of the limb. Elevation: Keeping the sprained joint elevated (in relation to ... Gamekeeper's thumb (Skier's thumb) - forceful grabbing that leads to an injury to the ulnar collateral ligament (UCL) at the ... Hung, Chen-Yu; Varacallo, Matthew; Chang, Ke-Vin (2020), "Gamekeepers Thumb (Skiers, Ulnar Collateral Ligament Tear)", ...
... well-developed major aortopulmonary collateral arteries demonstrated by multidetector computed tomography". Circulation. 124 ( ... Boshoff D, Gewillig M (June 2006). "A review of the options for treatment of major aortopulmonary collateral arteries in the ... In some cases of PAVSD, major aortopulmonary collateral arteries develop; in a normal fetus, these arteries usually develop but ... February 2021). "Prenatal diagnosis of major aortopulmonary collateral arteries (MAPCA) in fetuses with pulmonary atresia with ...
... about a third of the copies in circulation). The gazette also initiated a humanitarian campaign to help Bucharesters stricken ... The Românul founder was a collateral descendant of Antonie, and, despite being identified with Wallachia's liberal school, had ...
In a proof-of-stake model, owners put up their tokens as collateral. In return, they get authority over the token in proportion ... In the longer term, of the 10 leading cryptocurrencies identified by the total value of coins in circulation in January 2018, ... The market capitalization of a cryptocurrency is calculated by multiplying the price by the number of coins in circulation. The ... placing a cap on the total amount of that currency that will ever be in circulation. Compared with ordinary currencies held by ...
CIRCULATION GIVES A SIGN Gain Up to Oct. 14 Less Sharp Than In Preceding Week After Month's Record Climb. Decline in Gold ... Banks that did provide loans would require that the failing banks put up their most valuable assets as collateral, which would ...
Heatley suffered a broken jaw and arm, a sprained wrist and a torn anterior cruciate ligament (ACL) and medial collateral ... 37 was unofficially taken out of circulation after the death of Thrasher Dan Snyder in September 2003. No. 99 was retired ...
The monsoon circulation dominates across southern and eastern sections, due to the presence of the Himalayas forcing the ... He is internationally known for the concept of micro credit which allows poor and destitute people with little or no collateral ...
Each issue had a circulation of 12,000 to 50,000. In Front and Center: Critical Voices in the 99% was a fully-online ... huge collateral damage all throughout the country ... and yet you're still seeing some of the same folks who acted ...
He also began to have entertaining dialogues with the transnational circulation of ideas in contemporary art. For this dialogue ... Collateral project Union of Fire and Water, 11 video installation Fire talks to me, commissioned by Yarat Art Foundation, ...
In this way the USD value of Dai can be said to be backed by the USD value of the underlying collateral held by MakerDAO's ... MakerDAO is able to control the amount of Dai in circulation, and thus its value. The power to propose and implement changes to ... Users who deposit Ether (or other cryptocurrencies accepted as collateral) are able to borrow against the value of their ... Consequently, by repaying a loan and its accrued interest, the returned Dai is automatically destroyed, and the collateral is ...
When the trades went bad, multiple loans came due, all backed up by the same collateral. Historians agree that Grant was likely ... Silverites, who wanted more money in circulation to raise the prices that farmers received, denounced the move as the "Crime of ... Many farmers and workingmen favored the bill, which would have added $64 million in greenbacks to circulation, but some Eastern ... but they also caused inflation and forced gold-backed money out of circulation; Grant was determined to return the national ...
New Jersey made additional issues of currency to make loans to citizens for the purchase of land, which served as collateral ... A competing theory attributes the stability of New Jersey's currency to its circulation alongside precious metal coins or their ...
... partial anterior circulation infarct (PACI), lacunar infarct (LACI) or posterior circulation infarct (POCI). These four ... Vagal A, Aviv R, Sucharew H, Reddy M, Hou Q, Michel P, Jovin T, Tomsick T, Wintermark M, Khatri, P (2018). "Collateral Clock Is ... This is accomplished by inserting a catheter into the femoral artery, directing it into the cerebral circulation, and deploying ... Based on the extent of the symptoms, the stroke episode is classified as total anterior circulation infarct (TACI), ...
By the end of 1863, the amount of currency in circulation was three times more than needed by the economy, leading to inflation ... Though the government could not sell much of the produce due to the blockade, it did provide the government with collateral for ...
It appears in muscle tissue and in the circulation during exercise at levels up to one hundred times basal rates, as noted, and ... is co-transmitted with BDNF through paleo-spinothalamic circuitry from the periphery with collaterals into key areas of the ... It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise ... Circulation. 99 (16): 2221-2222. doi:10.1161/circ.99.16.2219/c. PMID 10217702. Wallenius V, Wallenius K, Ahrén B, Rudling M, ...
The Sequoyah County Times, founded by Wheeler Mayo in 1932, is called "the largest-circulation, non-metro, non-daily newspaper ... a collateral relative of noted Cherokee leader Stand Watie, laid out lots for a town. Several post offices had existed in the ...
Greening monetary policy: Aligning monetary policy with climate change objectives though reforms of central bank's collateral ... there is no longer a split circulation of money, just one integrated quantity of money circulating among banks and non-banks ...
Compensatory characteristics of diff levels of cerebral collateral circulation, collateral circulation & VaD relationship, & ... Relevance of the Collateral Circulation to VaD. Collateral Circulation and Atherosclerosis. Different from a single disease, ... Different Levels of Collateral Circulation and Its Compensation Characteristics. Collateral circulation in the brain is usually ... addresses the relationship between collateral circulation and VaD, and highlights that improving collateral circulation may be ...
To determine the factors that influence the presence of collateral vessels during coronary occlusion, we performed standardized ... Collateral Circulation / physiology* * Coronary Angiography* * Coronary Circulation / physiology* * Coronary Disease / ... Severity of single-vessel coronary arterial stenosis and duration of angina as determinants of recruitable collateral vessels ... To determine the factors that influence the presence of collateral vessels during coronary occlusion, we performed standardized ...
Acquired portal collateral circulation in the dog and cat. Vet Radiol Ultrasound. 2010 Jan-Feb;51(1):25-33 ... We describe patterns of acquired portal collateral circulation in dogs and in a cat using multidetector row computed tomography ... Small portal collaterals were termed varices; these collaterals had several patterns and were related either to portal vein or ... and the underlying causes of these collaterals as well. Knowledge about these collateral vessels is important before ...
Laser photoplethysmography in integrated evaluation of collateral circulation of lower extremities. Author. Pavlov, S. V. ...
Assess collateral circulation. If a baseline room air oxygen level is desired, patients should discontinue use of supplemental ... The sampling site of choice is the radial artery, unless tests of collateral circulation indicate otherwise. Samples also may ... Fingernail polish should be removed and peripheral circulation should be maximized by warming or by applying vasodilating cream ... particularly if circulation to the oximeter probe site is compromised by pressure on a treadmill handrail or ergometer handgrip ...
An MRI marker for collateral circulation in acute stroke?. K. Y. Lee, L. L. Latour, M. Luby, A. W. Hsia, J. G. Merino, S. ... An MRI marker for collateral circulation in acute stroke?. K. Y. Lee, L. L. Latour, M. Luby, A. W. Hsia, J. G. Merino, S. ... While the mechanism of HV remains to be established, stationary blood and slow antegrade or retrograde collateral circulation ... Good collateral blood flow in acute ischemic stroke is known to influence prognosis and infarct volume.15-17 The pial ...
... allowing collateral flow to pass between the anterior and posterior circulations. At its origin, the PCoA often has a widened ... The AChA is the only branch of the ICA that supplies a portion of both the anterior and posterior circulation, although the ... 25] Anastomoses of the PCA allow for collateral flow into the MCA via the anterior and posterior temporal arteries and into the ... Parmar H, Sitoh YY, Hui F. Normal variants of the intracranial circulation demonstrated by MR angiography at 3T. Eur J Radiol. ...
malignant collateral circulation, and so on), since treatment decisions can sometimes depend on collateral circulation status. ... sufficient/robust collateral circulation can be less serious than an LVO that has insufficient/malignant collateral circulation ... A severity of an LVO can depend on the status of the collateral circulation corresponding to the LVO (e.g., an LVO that has ... malignant) of the collateral circulation, can be critical for properly performing patient triage and making appropriate ...
Coronary arteriography showed three-vessel atherosclerotic disease with development of some collateral circulation. The patient ...
Collateral circulation of cavernous carotid artery: Anatomy. Can J Surg 7:251-268, 1964 Parkinson D: Collateral circulation of ... Collateral circulation of cavernous carotid artery: Anatomy.. Can J Surg. 7. :. 251. -. 268. , 1964. Parkinson D: Collateral ... circulation of cavernous carotid artery: Anatomy. Can J Surg 7:. 251-268, 1964. 14176972. ), false ...
10:44 Protective effect of coronary collateral circulation C. Seiler, Bern. *11:06 Progression of coronary artery calcification ... Working Group on Pulmonary Circulation & Right Ventricular Function Working Group on Aorta and Peripheral Vascular Diseases ...
The collateral circulation of the heart.. Prog Cardiovasc Dis, 31 (1988), pp. 57-77. Medline ...
This selective sparing is due to the collateral circulation offered to macular tracts by the middle cerebral artery.[15] ...
... after confirmation of good collateral circulation. The patient tolerated the procedure well, with improvement of her symptoms. ... based on collateral circulation and risk of intervention. Show more ...
Also improves coronary collateral circulation. Lower BP, increase HR, occasional paradoxical bradycardia ...
I too gained collateral circulation. I had had a total of 4 heart attacks. Had 2 stents put in. Had a heart attack last August ... "Frequency distribution of collateral flow and factors influencing collateral channel development. Functional collateral channel ... arteriogenesisblocked arteriescollateral arteriescollateral remodelingDr. Britta HardyO blood types and collateral arteriesSCAD ... But that part of my heart is now functioning on collateral circulation. The chest pain symptoms disappeared slowly as my ...
My lab focuses on the vascular biology of the collateral circulation. We have found that the abundance of collaterals-unique " ... is responsible for collateral insufficiency in humans. We have also identified a retinal biomarker for collateral abundance in ... Identification of the collaterogenesis pathway that this gene drives has led to the discovery that new collaterals can be ... A consequence is that individuals with poor collateral abundance suffer greater tissue injury when arterial obstruction occurs ...
Circulation. 93, 3, p. 567-576 10 p.. Research output: Contribution to journal › Article › peer-review ... Circulation. 89, 2, p. 712-717 6 p.. Research output: Contribution to journal › Article › peer-review ... Circulation. 89, 2, p. 718-723 6 p.. Research output: Contribution to journal › Article › peer-review ...
Pulse may be absent despite warm, pink hand due to collateral circulation ...
Guidelines for evaluation and management of cerebral collateral circulation in ischaemic stroke 2017. Liping Liu et al., Stroke ...
... of a smartphone camera functioning as a de facto photoplethysmograph to evaluate the adequacy of collateral circulation in ... provides an easily accessible and superior alternative to physical examination to assess radial collateral circulation. The ...
In MMD, a dilated AChA provides important collateral circulation along with posterior circulation. In brain infarcts, rapid ... In MMD, a dilated AChA provides collateral flow for posterior circulation. In brain infarcts, rapid treatment is necessary to ... In MMD, collaterals are more likely to arise from the choroidal arteries; therefore, the AChA may act as a major collateral ... Even if the AChA exhibits this collateral circulation, the AChA is highly vulnerable, and infarcts within this vessel can ...
Page 430: Potential Collateral Circulation Following Occlusion of Internal Cartoid Artery *Page 431: Vascular (Multi-Infarct) ...
Collateral circulation via leptomeningeal anastomosis plays an important role at some stages of moyamoya disease. Because this ... Although the mechanism of the ivy sign is likely to flow slowly in collateral vessels, the precise source of a high signal on ... slow retrograde flow via leptomeningeal collateral arteries was the most important pathophysiologic correlate. ... collateral flow is supposed to be very slow due to its retrograde direction via leptomeningeal anastomosis, it is likely that ...
... developing collateral circulation without sequelae. ... In both cases, normal circulation was present at age 13 months ... Close-up photograph of same patient with port incision and prominent collateral veins characteristic of superior vena cava ... lowering the extremity and keeping it warm produces vasodilation and improves circulation. The risks of surgery must be weighed ...
Injuries to arteries are surgically repaired unless they affect only small arteries with good collateral circulation. ... For example, children heal much faster than adults; disorders that impair peripheral circulation (eg, diabetes, peripheral ... medial and lateral collateral) or internal (anterior and posterior cruciate) ligaments or injuries of the menisci may result ...
The collateral circulation for occlusion of the three unpaired abdominal arteries * Full Text ...
A subtle connection between crossed cerebellar diaschisis and supratentorial collateral circulation in subacute and chronic ... Poor collateral flow with severe hypoperfusion explains worse outcome in acute stroke patients with atrial fibrillation.. Int J ...
The conus artery is a small early branch off the right coronary artery (RCA) circulation. Gross anatomy Supply The artery has a ... Pathways and functional significance of the coronary collateral circulation. Circulation. 1975;50 (4): 831-7. Pubmed citation ... another more important role it serves in pathophysiology is that of a route of collateral circulation. The conus artery has ... Vieussens arterial ring is an anastomotic conduit between the conus artery and the left coronary circulation 6. ...
  • To determine the factors that influence the presence of collateral vessels during coronary occlusion, we performed standardized contrast injection of the contralateral coronary artery in 58 consecutive patients, without previous myocardial infarction, undergoing percutaneous transluminal coronary angioplasty for 1-vessel disease (left anterior descending artery in 45, right coronary artery: in 10 and left circumflex artery in 3). (nih.gov)
  • The presence of collateral vessels during coronary occlusion, defined as partial or complete epicardial opacification by collateral vessels of the vessel dilated, was related to clinical, angiographic and electrocardiographic parameters. (nih.gov)
  • By combining lesion severity with the duration of angina, collateral vessels during coronary occlusion were particularly related to a lesion severity greater than or equal to 70% and duration of angina greater than or equal to 3 months (p less than 0.001). (nih.gov)
  • Furthermore, the presence of collateral vessels was associated with an absence of ST-segment shift (greater than or equal to 1 mm) during 1 minute of coronary occlusion (p less than 0.001). (nih.gov)
  • Imaging plays a pivotal role in determining the origin, course, and termination of these vessels, and the underlying causes of these collaterals as well. (clinicaveterinariasanmarco.it)
  • Knowledge about these collateral vessels is important before interventional procedures, endosurgery or conventional surgery are performed, so as to avoid uncontrollable bleeding if they are inadvertently disrupted. (clinicaveterinariasanmarco.it)
  • left panel) and without (right panel) collateral artery growth between the right coronary artery (these are the small red blood vessels in the left illustration) and the blocked artery. (myheartsisters.org)
  • Some researchers suggest that, because Juliet was already a physically active runner, her own collateral arteries may have already started this important process called arteriogenesis , which is defined as the transformation of pre-existing collateral artery pathways into conducting vessels . (myheartsisters.org)
  • My misdiagnosis also meant that I'd been sent home from Emergency despite my textbook cardiac symptoms (central chest pain, nausea, sweating and pain down my left arm) - ironically signalling the pre-existing collateral vessels to get ready because my heart was in trouble. (myheartsisters.org)
  • We have found that hypertension, diabetes and hyperlipidemia, as well as advanced age and Alzheimer's disease cause selective loss of collateral vessels. (unc.edu)
  • This is collateral enhancing therapy - it is dilating the blood vessels around the blocked vessel. (medscape.com)
  • We speculate that HV may be the result of beneficial collateral arterial flow beyond the site of arterial occlusion, and those patients with HV will have a better prognosis and smaller infarction size than those patients without HV. (neurology.org)
  • Although an acute occlusion of the tiny artery has been shown to result in S-T elevation, another more important role it serves in pathophysiology is that of a route of collateral circulation. (radiopaedia.org)
  • Even advanced PAD may not produce claudication or other symptoms if the occlusion develops slowly, allowing sufficient collateral circulation to develop, or if the patient is mostly sedentary. (aafp.org)
  • Data from a prospective observational multicenter registry was screened to identify acute ischemic stroke patients with an anterior circulation large vessel occlusion who underwent mechanical thrombectomy. (nih.gov)
  • Collateral circulation, a compensation mechanism for CBF, provides an alternative vascular pathway for blood to reach ischemic tissues, which has been confirmed to be associated with better clinical outcomes of ischemic diseases. (dovepress.com)
  • At present, considerable effort has been devoted to enhancing the functional prognosis of acute ischemic stroke by improving collateral circulation. (dovepress.com)
  • Since ischemic stroke is the primary contributor to VaD, it is necessary to explore whether improving collateral circulation is beneficial to prevent or slow the progression of VaD. (dovepress.com)
  • The approach involves inserting a small electrode the size of a toothpick into the soft palate to stimulate the sphenopalatine ganglion, the source of parasympathetic innervation to the anterior cerebral circulation, with the aim of increasing collateral circulation and maintaining blood flow to vulnerable ischemic tissue in acute ischemic stroke. (medscape.com)
  • Saver explained that good collateral blood flow is associated with slower infarct expansion, and improved prognosis and outcome in patients with acute ischemic stroke. (medscape.com)
  • For the study, 1000 patients with anterior-circulation acute ischemic stroke, not undergoing reperfusion therapy, were randomized to receive active sphenopalatine ganglion stimulation or sham stimulation (control) starting 8 to 24 hours after stroke onset (median 19 hours). (medscape.com)
  • Researchers identified observational studies that reported associations between SP before hospital admission with collateral circulation and FIV in patients with acute ischemic stroke. (neurologyadvisor.com)
  • My lab focuses on the vascular biology of the collateral circulation. (unc.edu)
  • disorders that impair peripheral circulation (eg, diabetes, peripheral vascular disease) slow healing. (merckmanuals.com)
  • In contrast to earlier CT scan-only studies, these trials required more brain and vascular imaging to define, "the presence, sites and extent" of intracranial arterial occlusions as well as the extent of tissue damage and collateral circulation, they pointed out. (medpagetoday.com)
  • Orthodontic forces may impede pulp circulation, causing vascular congestion and pulp edema, leading to pulp damage 14,27 and even necrosis in teeth submitted to traction [29]. (bvsalud.org)
  • For the first time in a human being with entirely normal coronary arteries, we have shown evidence of enhanced coronary collateral flow in response to an endurance exercise program. (myheartsisters.org)
  • Having O type blood , for example, was found to be an independent predictor of good coronary collateral circulation among heart attack patients. (myheartsisters.org)
  • Pathways and functional significance of the coronary collateral circulation. (radiopaedia.org)
  • 786T/c endothelial nitric oxide synthase gene polymorphism and coronary collateral circulation. (cdc.gov)
  • Genetic association study of coronary collateral circulation in patients with coronary artery disease using 22 single nucleotide polymorphisms corresponding to 10 genes involved in postischemic neovascularization. (cdc.gov)
  • Resolution of mitochondrial oxidative stress rescues coronary collateral growth in Zucker obese fatty rats. (omeka.net)
  • OBJECTIVE: We have previously found abrogated ischemia-induced coronary collateral growth in Zucker obese fatty (ZOF) rats compared with Zucker lean (ZLN) rats. (omeka.net)
  • The mechanistic basis for the disparate effects of angiotensin II on coronary collateral growth. (omeka.net)
  • Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth. (omeka.net)
  • Reactive oxygen species (ROS) are implicated in coronary collateral growth (CCG). (omeka.net)
  • Redox-dependent mechanisms in coronary collateral growth: the 'redox window' hypothesis. (omeka.net)
  • This review addresses the complexity of coronary collateral growth from the aspect of redox signaling and introduces the concept of a 'redox window' in the context of collateral growth. (omeka.net)
  • With minimal risk of radiation, CT is indispensable to providing essential information regarding the size of an infarct, the affected territory, core infarct volume, and collateral supply (Figure 1). (appliedradiology.com)
  • A more recent small study (Circulation 2013;128:1495) of patients with anterior STEMI and Killip class II or less heart failure who were undergoing PCI resulted in significantly smaller infarct size, as measured by MRI, in patients who received IV metoprolol compared to placebo. (blogspot.com)
  • patients with proximal and distal as well as anterior and posterior circulation occlusions were considered together, potentially confounding tests for significance. (neurology.org)
  • In MMD, a dilated AChA provides collateral flow for posterior circulation. (medsci.org)
  • Even when the proximal AChA or internal carotid artery (ICA) are occluded, retrograde filling of the AChAs from the posterior circulation has been observed on a vertebral angiogram [ 12 ]. (medsci.org)
  • 7 However, in a recently published study, Caruso, et al, have demonstrated the feasibility and validity of the posterior circulation Alberta stroke program early CT score (Pc-ASPECTS) in 50 patients with posterior circulation strokes. (appliedradiology.com)
  • A linked research paper reporting on the effectiveness of a smartphone camera functioning as a de facto photoplethysmograph to evaluate the adequacy of collateral circulation in patients scheduled for cardiac catheterization via radial artery access offers an excellent example of the opportunities presented by these technologies. (cmaj.ca)
  • The 2 ACAs connect through the anterior communicating artery (ACoA), thus joining the left and right carotid circulations. (medscape.com)
  • The PCoA extends posteriorly to connect with the primary segment of the posterior cerebral artery (PCA), allowing collateral flow to pass between the anterior and posterior circulations. (medscape.com)
  • I've been told the same theory - that my 19 years of distance running contributed to that enhanced corona ry collateral flow , which may have been the factor that helped to save me during my own heart attack, despite having a Left Anterior Descending coronary artery that was also fully occluded. (myheartsisters.org)
  • The conus artery is a small early branch off the right coronary artery (RCA) circulation. (radiopaedia.org)
  • Vieussens' arterial ring is an anastomotic conduit between the conus artery and the left coronary circulation 6 . (radiopaedia.org)
  • The conus artery has been shown to collateralise with the more distal acute marginal branch in RCA stenosis/obstruction, and collateralise with the left anterior descending artery (LAD) in LAD stenosis/obstruction, providing a potentially vital collateral pathway. (radiopaedia.org)
  • MALS can be asymptomatic in 10-24% of the patients due to a robust collateral circulation from the superior mesenteric artery (SMA) [ 3 ]. (hindawi.com)
  • The workup in a patient with possible renal artery stenosis includes laboratory studies of kidney function and imaging studies of the kidneys and renal circulation (see Workup). (medscape.com)
  • Central investigators, masked to clinical information other than stroke side, categorised baseline imaging features of ischaemic change with the Alberta Stroke Program Early CT Score (ASPECTS) or according to involvement of more than 33% of middle cerebral artery territory, and by thrombus volume, hyperdensity, and collateral status. (elsevier.com)
  • Coronary arteriography showed three-vessel atherosclerotic disease with development of some collateral circulation. (cdc.gov)
  • Even if the AChA exhibits this collateral circulation, the AChA is highly vulnerable, and infarcts within this vessel can result in a devastating outcome for patients [ 13 ]. (medsci.org)
  • Only trials that required vessel imaging to identify patients with proximal anterior circulation ischaemic stroke and that used predominantly stent retrievers or second-generation neurothrombectomy devices in the EVT group were included. (elsevier.com)
  • Thrombus obstructing the deep veins may lead to the development of a collateral circulation and dilated superficial veins may be visible. (nursinginpractice.com)
  • There are more collaterals in the superficial lining of the brain that go the cortical region than go to the deeper regions, so we would expect patients with cortical strokes to respond better. (medscape.com)
  • An MRI marker for collateral circulation in acute stroke? (neurology.org)
  • A prospective study involving 11 stroke centers began in 2015 to determine if the same or related gene(s) is responsible for collateral insufficiency in humans. (unc.edu)
  • ASPECTS was conventionally considered applicable only to the anterior circulation. (appliedradiology.com)
  • While the mechanism of HV remains to be established, stationary blood and slow antegrade or retrograde collateral circulation have been suggested as possible explanations for HV. (neurology.org)
  • And not everybody has functional collateral arteries (a blood flow of 20% to 25% is generally considered sufficient to provide the required blood supply to the heart muscle at rest). (myheartsisters.org)
  • Consider also the example of Juliet's life-saving collateral arteries. (myheartsisters.org)
  • The chest pain symptoms disappeared slowly as my collateral arteries developed. (myheartsisters.org)
  • My cardiologists said these collateral arteries would have started to develop as soon as my LAD started to re-stenose, especially as I went straight back to running, post-cardiac rehab. (myheartsisters.org)
  • As of November 2021, there were over 18.8 million bitcoins in circulation with a total market cap of around $1.2 trillion. (vontera.com)
  • A consequence is that individuals with poor collateral abundance suffer greater tissue injury when arterial obstruction occurs. (unc.edu)
  • This article reviews the compensatory characteristics of different levels of cerebral collateral circulation, addresses the relationship between collateral circulation and VaD, and highlights that improving collateral circulation may be a potential adjunctive strategy in preventing and slowing the progression of VaD. (dovepress.com)
  • he grey area below the blockage shows the area of the heart muscle at risk of permanent damage in the absence of collaterals. (myheartsisters.org)
  • The change would be done to reduce the amount of money in circulation and control inflation, according to the CBN Governor, Godwin Emefiele. (theexchange.africa)
  • Various combinations of herbal liniments, balms and essential oils are used to promote blood flow to the region and supply analgesic (pain relieving) effects through relaxing muscles, and promoting circulation. (sacredsilenceacupuncture.com)
  • The burning of the herb "Mugwort" over acupuncture points with or without needles to promote blood flow and circulation. (sacredsilenceacupuncture.com)
  • Does not include securities pledged as collateral to foreign official and international account holders against reverse repurchase agreements with the Federal Reserve presented in tables 1, 5, and 6. (federalreserve.gov)
  • While these securities are often long-dated and have a somewhat larger coupon than the yield of comparable-maturity long-dated securities, "these securities are acceptable as collateral for market repo transactions but not as SLR (Statutory Liquidity Ratio) securities. (theinvestingcouncil.com)
  • If the injury in question is arterial, lowering the extremity and keeping it warm produces vasodilation and improves circulation. (medscape.com)
  • We have found that naturally occurring variants of a single novel gene account for most of the variation in mouse through this gene's primary role in governing the formation of collaterals-which occurs in the embryo. (unc.edu)
  • Identification of the collaterogenesis pathway that this gene drives has led to the discovery that new collaterals can be induced to form in adult tissues. (unc.edu)
  • Some researchers suggest that your blood type may affect the likelihood that your body will produce collateral circulation. (myheartsisters.org)
  • The investigators pooled both odds ratios (OR) and standardized mean differences (SMDs) on the collateral status and FIV based on SP history. (neurologyadvisor.com)
  • A com - bination of long, gentle strokes induce deep relaxation while improving circulation to give the skin a radiant glow. (mandaraspa.com)
  • Severe plumbing emergencies in Knoxville, AL 35469 can cause a lot of collateral damage and result in high costs if not addressed immediately. (jcplumbingcontractor.com)
  • This product provides practitioners a safe and effective method of supporting the normal microbiome via nature's self-limiting process of microbial balance, while completely avoiding collateral damage associated with other methodologies. (forresthealth.com)
  • it happens through a remodeling process of those pre-existing small collaterals. (myheartsisters.org)
  • Limitations of the analysis were the inclusion of mostly small observational cohorts, as well as the lack of data on FIV and collateral scores in the majority of the included studies. (neurologyadvisor.com)
  • The shunt leads to a state where the right side of heart and the pulmonary circulation suffers a volume and pressure increase which can be suspected on chest radiographs. (bme.hu)
  • These accomplishments are merely collateral to his primary goal. (infoplease.com)
  • BitShares is a public, blockchain-based, real-time financial platform.It provides a decentralised asset exchange.BTS is a cryptocurrency token, which can be transferred between accounts, and is used to collect fees for network operations and as a collateral for loans. (mindmapped.org)
  • The quantity of currency that you'll need to deposit as collateral will differ depending upon the token or coin that you're using the back your loan. (africanchamberdfw.org)
  • In 2004, Swiss researchers, for example, found that enhanced physical exertion (like running) may indeed help those tiny collaterals to kick into creating that detour around a blockage. (myheartsisters.org)
  • Cell phone technology provides an easily accessible and superior alternative to physical examination to assess radial collateral circulation. (cmaj.ca)
  • He gave the bank some stocks and bonds as collateral for the money he borrowed. (infoplease.com)
  • The reason for having collateral is the need to minimize price fluctuation and provide proof for adopters that there is value behind the coin and their money can be liquidated at any moment. (guarda.com)
  • These coins are common and where used in circulation and have no collector value. (pawnidaho.com)
  • How Many NBS Coins Are There in Circulation? (mindmapped.org)
  • So why is Tether lending USDT to Celsius in return for bitcoin/ethereum collateral? (blogspot.com)
  • These loans, which are processed without backing collateral, can be executed within seconds and are used in trading. (vontera.com)