Collagen Diseases
Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)
Caplan Syndrome
Retropharyngeal Abscess
Lung Diseases, Interstitial
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
Detection of anti-cytokeratin 8 antibody in the serum of patients with cryptogenic fibrosing alveolitis and pulmonary fibrosis associated with collagen vascular disorders. (1/154)
BACKGROUND: It has been suggested that the humoral immune system plays a role in the pathogenesis of cryptogenic fibrosing alveolitis (CFA). Although circulating autoantibodies to lung protein(s) have been suggested, none of the lung proteins have been characterised. The purpose of this study was to determine the antigen to which the serum from patients with pulmonary fibrosis reacted. METHODS: The anti-A549 cell antibody was characterised in a patient with CFA using Western immunoblotting and immunohistochemical staining of A549 cells. As we identified that one of the antibodies against A549 cells was anti-cytokeratin 8, the expression of mRNA of cytokeratin 8 in A549 cells was evaluated. In addition, we attempted to establish an enzyme linked immunosorbent assay to measure the levels of anti-cytokeratin 8 antibody in the serum of patients with CFA and pulmonary fibrosis associated with collagen vascular disorders (PF-CVD). RESULTS: Initially two anti-A549 cell antibodies were detected in the serum of patients with pulmonary fibrosis, one of which was characterised as anticytokeratin 8 antibody by Western immunoblotting. We were able to establish an ELISA to measure anti-cytokeratin 8 antibody and found significantly higher levels in patients with CFA and PF-CVD than in normal volunteers, patients with sarcoidosis, pneumonia, and pulmonary emphysema. CONCLUSIONS: One of the anti-A549 cell antibodies in the serum of patients with CFA was against cytokeratin 8. The serum levels of anti-cytokeratin 8 antibody were increased in patients with CFA and PF-CVD. These results suggest that anticytokeratin 8 antibody may be involved in the process of lung injury in pulmonary fibrosis. (+info)Collagenous gastritis and collagenous colitis: a report with sequential histological and ultrastructural findings. (2/154)
The case is reported of a young adult man with collagenous gastritis, an extremely rare disorder with only three case reports in the English literature, who subsequently presented with collagenous colitis. Sequential gastric biopsies showed a notable increase in thickness of the subepithelial collagen band. Ultrastructural study of gastric and rectal mucosa showed the characteristic subepithelial band composed of haphazardly arranged collagen fibres, prominent degranulating eosinophils, and activated pericryptal fibroblasts. (+info)Elevated serum and BAL cytokeratin 19 fragment in pulmonary fibrosis and acute interstitial pneumonia. (3/154)
Cytokeratin 19 fragment (CK19) levels in serum have already been documented as a useful tumour marker for lung cancer. In the present study, it was hypothesized that CK19 may be increased in the serum and epithelial lining fluid of the respiratory tract from patients with pulmonary fibrosis. CK19 was measured in the serum and bronchoalveolar lavage fluid (BALF) of patients with pulmonary fibrosis and the correlation between CK19 levels and clinical parameters evaluated. Nineteen patients diagnosed with idiopathic pulmonary fibrosis (IPF), eight with pulmonary fibrosis associated with a collagen vascular disorder (PF-CVD), seven patients with acute interstitial pneumonia (AIP), and 10 normal smokers as a control group were studied. CK19 levels in sera of patients with IPF and patients with PF-CVD were significantly increased compared to those of normal smokers. CK19 levels in sera of patients with AIP were significantly increased compared to those of other groups. CK19 values in the BALF of patients with pulmonary fibrosis were significantly elevated compared to those of normal smokers. CK19 values in sera charged according to the progression or improvement of the acute lung injury. Immunohistochemical study using pulmonary tissues obtained from patients with AIP demonstrated that the hyaline membrane and proliferating type II pneumocytes were stained by anti-human cytokeratin 19 antibody. These data demonstrated that the measurement of cytokeratin 19 fragment is a useful parameter to evaluate the activity of lung epithelial cell damage and repair. (+info)Collagen dysplasia (cutaneous asthenia) in a cat. (4/154)
Hereditary collagen dysplasias comprise a complex group of connective-tissue disorders that result in the reduced tensile strength of affected tissues. These processes are called cutaneous asthenia in the skin of dogs and cats. We report here the case of a crossbred male cat, aged 6 months, that presented with two skin wounds in the region of the right thorax and right iliac tuberosity. The skin of these regions and of the animal's dorsum was hyperextensible, smooth to the touch, and easily torn with minor trauma. Microscopic examination of skin samples revealed reduced dermal connective tissue consisting of shortened and fragmented collagen fibers. Normal fibers were intermingled with altered fibers. Ultrastructural changes in collagen fibers included disorientation of fibrils within the same bundle, marked spacing differences, and variation in the diameter of transverse sections. The fibrils maintained the transverse striations characteristic of normal collagen. (+info)Report of five novel and one recurrent COL2A1 mutations with analysis of genotype-phenotype correlation in patients with a lethal type II collagen disorder. (5/154)
Achondrogenesis II-hypochondrogenesis and severe spondyloepiphyseal dysplasia congenita (SEDC) are lethal forms of dwarfism caused by dominant mutations in the type II collagen gene (COL2A1). To identify the underlying defect in seven cases with this group of conditions, we used the combined strategy of cartilage protein analysis and COL2A1 mutation analysis. Overmodified type II collagen and the presence of type I collagen was found in the cartilage matrix of all seven cases. Five patients were heterozygous for a nucleotide change that predicted a glycine substitution in the triple helical domain (G313S, G517V, G571A, G910C, G943S). In all five cases, analysis of cartilage type II collagen suggested incorporation of the abnormal alpha1(II) chain in the extracellular collagen trimers. The G943S mutation has been reported previously in another unrelated patient with a strikingly similar phenotype, illustrating the possible specific effect of the mutation. The radiographically less severely affected patient was heterozygous for a 4 bp deletion in the splice donor site of intron 35, likely to result in aberrant splicing. One case was shown to be heterozygous for a single nucleotide change predicted to result in a T1191N substitution in the carboxy-propeptide of the proalpha1(II) collagen chain. Study of the clinical, radiographic, and morphological features of the seven cases supports evidence for a phenotypic continuum between achondrogenesis II-hypochondrogenesis and lethal SEDC and suggests a relationship between the amount of type I collagen in the cartilage and the severity of the phenotype. (+info)Clinical evaluation of idiopathic interstitial pneumonia and interstitial pneumonia associated with collagen vascular disease using logistic regression analysis. (6/154)
OBJECTIVE: To clarify the differences in the clinical features between idiopathic interstitial pneumonia (IIP) and interstitial pneumonia associated with collagen vascular diseases (CVD-IP). METHODS: Symptoms, radiographic findings, pulmonary function, blood chemistry data including autoantibody, and bronchoalveolar lavage fluid (BALF) findings were compared using multiple logistic regression analysis. PATIENTS: The subjects were 44 patients clinically diagnosed with IIP and 33 patients with CVD-IP. RESULTS: The clinical features related to IIP were as follows: male sex, advanced age, past history of hypertension, presence of cough, exertional dyspnea, digital clubbing, an increased level of gamma-globulin, decreased lung volume on chest X-ray, and typical type according to the criteria for IIP on chest X-ray. Increased levels of rheumatoid factor and total cell number in BALF were related to CVD-IP. CONCLUSION: These findings are considered to be useful to differentiate IIP and CVD-IP. (+info)Role of carbohydrate antigens sialyl Lewis (a) (CA19-9) in bronchoalveolar lavage in patients with pulmonary fibrosis. (7/154)
BACKGROUND: It has been reported that carbohydrate antigen sialyl Lewis (a) (CA19-9) levels are elevated in serum as well as in bronchoalveolar lavage fluid (BALF) of patients with pulmonary fibrosis. However, the biological significance of CA19-9 is unclear. OBJECTIVE: The purpose of the present study was to evaluate correlations between CA19-9 levels in BALF and several biochemical as well as clinical parameters in patients with pulmonary fibrosis. In addition, biological functions of CA19-9 were also examined. METHODS: We studied 24 patients with a diagnosis of pulmonary fibrosis: 16 with idiopathic pulmonary fibrosis (IPF) and 8 with pulmonary fibrosis associated with a collagen vascular disorder (PF-CVD). In BALF, carbohydrate antigens sialyl Lewis (a) (CA19-9), elastase: alpha(1)-proteinase inhibitor complex (E-PI), hepatocyte growth factor (HGF), LDH, IgG, IgA, albumin, and cell differentiation were measured. We also evaluated the effects of CA19-9 on neutrophil functions. RESULTS: CA19-9/albumin levels in BALF significantly correlated with HGF/albumin, elastase/albumin, LDH/albumin, total number of alveolar macrophages, and total number of neutrophils. Purified CA19-9 had a chemotactic activity for neutrophils. In addition, neutrophil chemotactic activity to C5a, fMLP, and interleukin 8 was significantly stimulated after incubation with purified CA19-9. Furthermore, CA19-9 increased the expression of CD15s on neutrophils. CONCLUSIONS: Our data demonstrated (i) CA19-9 in BALF correlated with other markers of inflammation in pulmonary fibrosis, and (ii) CA19-9 can modify neutrophil functions. These results suggest that CA19-9 may play a role in the process of lung injury in patients with pulmonary fibrosis. (+info)Alternate-day prednisone therapy and human lymphocyte subpopulations. (8/154)
The mechanisms and kinetics of the immunosuppressive effects of alternate-day prednisone were investigated in a group of patients with a variety of inflammatory diseases receiving a range of alternate-day prednisone doses from 5 to 120 mg. Total circulating lymphocyte and monocyte counts, as well as proportions of lymphocyte subpopulations defined both by surface markers and by in vitro functional capacities, were studied. At 8 a. m. of the day on prednisone, just before drug administration, lymphocyte and monocyte counts, proportions of lymphocyte subpopulations, as well as in vitro lymphocyte blastogenic responses to various mitogenic and antigenic stimuli were normal. 4 h after the administration of prednisone, there was a profound lymphocytopenia and monocytopenia, with a differential depletion of thymus-derived lymphocytes as well as various functionally defined lymphocyte subpopulations. Lymphocyte kinetic studies using a radioactive chromium-labeled autologous lymphocytes showed that the lymphocytopenia was due predominantly to a transient depletion of the recirculating portion of the intravascular lymphocytepool. All these parameters returned to normal by 8 a.m. of the following day (off prednisone) and remained normal throughout the day. This very transient lymphocytopenia and monocytopenia after prednisone, with normal cell numbers, proportions, and functions throughout the remainder of the 2-day cycle, was associated with suppression of disease activity, yet did not affect cutaneous delayed hypersensitivity in these patients nor increase the likelihood of infectious complications. This drug-associated cyclic and transient monocytopenia and selective lymphocytopenia is best explained by a redistribution of recirculating lymphocytes to other body compartments, particularly the bone marrow. (+info)
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Collagen disease
... is a term previously used to describe systemic autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus ... Collagen disease, Autosomal dominant disorders, All stub articles, Musculoskeletal disease stubs). ... ISBN 0-8027-0449-2. Collagen disease entry in the public domain NCI Dictionary of Cancer Terms This article incorporates public ... "collagen disease" was coined by Dr. Alvin F. Coburn in 1932, on his quest to discover streptococcal infection as the cause for ...
Collagen, type IV, alpha 4
2003). "Type-IV collagen related diseases". J. Nephrol. 16 (2): 314-6. PMID 12768082. Torra R, Tazón-Vega B, Ars E, Ballarín J ... Hudson BG, Reeders ST, Tryggvason K (1994). "Type IV collagen: structure, gene organization, and role in human diseases. ... Collagen alpha-4(IV) chain is a protein that in humans is encoded by the COL4A4 gene. This gene encodes one of the six subunits ... This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the ...
Collagen, type IV, alpha 3
2003). "Type-IV collagen related diseases". J. Nephrol. 16 (2): 314-6. PMID 12768082. Torra R, Tazón-Vega B, Ars E, Ballarín J ... Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene. Type IV collagen, the major structural ... 1987). "Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of ... Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another ...
Collagen loss
"Protein losing enteropathy associated with collagen diseases". Annals of the Rheumatic Diseases. 50 (3): 178-81. doi:10.1136/ ... When collagen is lost in large amounts, it may cause wrinkles to emerge. Tobacco use can also result in slow collagen healing. ... Most collagen belongs to types 1, 2 and 3. Collagen consists mainly of amino acids and can be mostly found in tendons, muscles ... The use of tobacco can cause damage to the skin's collagen layer. It can cause the skin around the lips to lose collagen when ...
Lysine
Hydroxylysine-deficient collagen disease". The New England Journal of Medicine. 286 (19): 1013-20. doi:10.1056/ ... a lack of lysine and hydroxylysine involved in the crosslinking of collagen peptides has been linked to a disease state of the ... Diseases related to lysine are a result of the downstream processing of lysine, i.e. the incorporation into proteins or ... It is often due to a metabolic disease in which a protein involved in the breakdown of lysine is non functional due to a ...
Collagen, type VII, alpha 1
Disease Primers. 6 (1): 78. doi:10.1038/s41572-020-0210-0. PMID 32973163. S2CID 221861310. "COL7A1 collagen, type VII, alpha 1 ... Gatseva A, Sin YY, Brezzo G, Van Agtmael T (September 2019). "Basement membrane collagens and disease mechanisms". Essays in ... The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath ... Epidermolysis bullosa acquisita involves an autoimmune reaction to this form of collagen. Collagen, type VII, alpha 1 forms a ...
Intestinal pseudo-obstruction
Takahashi, Hiroki; Ohara, Mikiko; Imai, Kohzoh (June 2004). "[Collagen diseases with gastrointestinal manifestations]". Nihon ... "Hirschsprung disease". GARD: Genetic and Rare Diseases Information Center. 4 September 2017. Retrieved 8 November 2021.{{cite ... Conditions and onset will vary if the disease is primary vs secondary and the underlying disease (if a secondary manifestation ... disease - a chronic parasitic infection of the colon leading to loss of nerve endings Kawasaki disease - a rare presentation ...
Robert Ira Lewy
March 1994). "Autoimmune disease and collagen dermal implants". Annals of Internal Medicine. American College of Physicians. ... Lewy, RI (1994). "Autoimmune disease and collagen dermal implants". Annals of Internal Medicine. 120 (6): 524-525. doi:10.7326/ ... Robert Ira Lewy (born October 16, 1943) is an American doctor who has conducted research on aspirin therapy in heart disease ... 1980). "Effect of Elevated Plasma-Free Fatty Acids on Thromboxane Release in Patients with Coronary Artery Disease". ...
Connective tissue disease
Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. Collagen ... Psoriatic arthritis is also a collagen vascular disease. Peyronie's disease - involving the growth of abnormal collagen (Type I ... Osteogenesis imperfecta (brittle bone disease) - caused by poor quality collagen, or insufficient amounts of normal collagen ( ... The classic collagen vascular diseases have a "classic" presentation with typical findings that doctors can recognize during an ...
Collagen
Type I collagen gives bone its tensile strength. Collagen-related diseases most commonly arise from genetic defects or ... With type I collagen and possibly all fibrillar collagens, if not all collagens, each triple-helix associates into a right- ... The synthesis of collagen occurs inside and outside of the cell. The formation of collagen which results in fibrillary collagen ... Multiple collagen fibrils form into collagen fibers. Collagen may be attached to cell membranes via several types of protein, ...
GPR56
Luo R, Jin Z, Deng Y, Strokes N, Piao X (2012). "Disease-associated mutations prevent GPR56-collagen III interaction". PLOS ONE ... Luo R, Jeong SJ, Jin Z, Strokes N, Li S, Piao X (August 2011). "G protein-coupled receptor 56 and collagen III, a receptor- ... Jin Z, Tietjen I, Bu L, Liu-Yesucevitz L, Gaur SK, Walsh CA, Piao X (August 2007). "Disease-associated mutations affect GPR56 ... GPR56 was the first adhesion GPCR causally linked to a disease. Loss-of-function mutations in GPR56 cause a severe cortical ...
Adhesion G protein-coupled receptor
Luo, R; Jin, Z; Deng, Y; Strokes, N; Piao, X (2012). "Disease-Associated Mutations Prevent GPR56-Collagen III Interaction". ... The N-terminus of GPR56 is naturally glycosylated, but this glycosylation is not necessary for collagen III binding. Collagen ... The binding of collagen III to GPR56 occurs on the N-terminus and has been narrowed down to a short stretch of amino acids. ... One adhesion GPCR, GPR56, has a known ligand, collagen III, which is involved in neural migration inhibition. GPR56 has been ...
Myocardial infarction diagnosis
Enhanced deposition of predominantly type I collagen in myocardial disease. J Mol Cell Cardiol. 1990;22:1157-1165 Table 11-2 in ... Aging-associated diseases, Cardiovascular diseases, Ischemic heart diseases, Medical emergencies, Cardiac procedures). ... Anonymous (March 1979). "Nomenclature and criteria for diagnosis of ischemic heart disease. Report of the Joint International ... "Radial artery versus femoral artery approach for performing coronary catheter procedures in people with coronary artery disease ...
Jean Baum
Baum, Jean; Brodsky, Barbara (1999-02-01). "Folding of peptide models of collagen and misfolding in disease". Current Opinion ... and collagen. The molecular interactions involved in the assembly of the functional and pathological forms of these proteins ... "Characterization of collagen-like peptides containing interruptions in the repeating Gly-X-Y sequence". Biochemistry. 32 (43): ...
Cenderitide
Weber KT (June 1989). "Cardiac interstitium in health and disease: the fibrillar collagen network". Journal of the American ... Regulation of fibrillar collagen mRNAs and expression of early transcription factors". Circulation Research. 69 (2): 483-90. ... Bonnin CM, Sparrow MP, Taylor RR (November 1981). "Collagen synthesis and content in right ventricular hypertrophy in the dog ... Additionally, in vitro study of human fibroblasts demonstrates that cenderitide reduces TGF-beta 1 induced collagen production ...
Shangri-La (novel)
She suffers from a collagen disease and thus cannot bear sunlight. She has the uncanny ability to see through lies and ... in front of Sayoko and Mikuni to bid Mikuni a final farewell and using some kind of power to cure Mikuni of her disease and ...
Osteogenesis imperfecta
Collagen disease, Rare diseases, Wikipedia medicine articles ready to translate). ... "Molecular and mesoscale mechanisms of osteogenesis imperfecta disease in collagen fibrils". Biophysical Journal. 97 (3): 857- ... Collagen is fatally defective at its C-terminus.: 1512 Most cases result in death shortly after birth, or within the first year ... Causes disease clinically similar to types II and III, thought to be related to inability of chaperone protein HP47 to unbind ...
Vitamin C
Until quite late in the disease the damage is reversible, as healthy collagen replaces the defective collagen with vitamin C ... Prockop DJ, Kivirikko KI (1995). "Collagens: molecular biology, diseases, and potentials for therapy". Annual Review of ... including wound healing and collagen synthesis. In humans, vitamin C deficiency leads to impaired collagen synthesis, ... The disease was shown to be prevented by citrus fruits in an early controlled trial by a Royal Navy surgeon, James Lind, in ...
Wheat allergy
"Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease". Gut. 55 (4): 478-84. doi: ... While gluten is also the causative agent of celiac disease (CD), celiac disease can be contrasted to gluten allergy by the ... Gluten sensitivity and Coeliac disease are two different diseases even if the management could be similar. Management of wheat ... Pietzak M (Jan 2012). "Celiac disease, wheat allergy, and gluten sensitivity: when gluten free is not a fad". JPEN J Parenter ...
Brain healing
"Collagen May Help Protect Brain Against Alzheimer's Disease", Science Daily, Dec. 10, 2008. Retrieved Oct 21st 2013. "Study ... A scar is formed by fibroblasts producing collagen to repair an area, which will later contract. If scars did form in the brain ... Recent studies have found collagen is extensively distributed throughout the brain and may be essential in protecting the brain ... Neuroregeneration Seppänen A, Suuronen T, Hofmann SC, Majamaa K, Alafuzoff I (Jul 2007). "Distribution of collagen XVII in the ...
Eosinophil
... autoimmune and collagen vascular disease (such as rheumatoid arthritis) and Systemic lupus erythematosus; malignant diseases ... extensive skin diseases (such as exfoliative dermatitis); Addison's disease and other causes of low corticosteroid production ( ... The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma ... Furthermore, mucosal bronchial biopsies conducted on patients with diseases such as asthma have been found to have higher ...
Couvelaire uterus
... and other collagen disease complicating pregnancy; prevention of trauma during pregnancy; mothers should also avoid smoking or ... This includes proper management of hypertensive states of pregnancy; treatment of maternal diseases like diabetes mellitus, ...
Osteoblast
Kuivaniemi H, Tromp G, Prockop DJ (April 1991). "Mutations in collagen genes: causes of rare and some common diseases in humans ... The active osteoblast produces substantial collagen type I. About 10% of the bone matrix is collagen with the balance mineral. ... Thus, the collagen and mineral together are a composite material with excellent tensile and compressive strength, which can ... Defects in collagen type I cause the commonest inherited disorder of bone, called osteogenesis imperfecta. Minor, but important ...
Scleromyositis
In most cases it is observed that the disease involves an overproduction of collagen. Diagnosis is by skin tests. Typically, ... Scleromyositis, is an autoimmune disease (a disease in which the immune system attacks the body). People with scleromyositis ... Although it is a rare disease, it is one of the more common overlap syndromes seen in scleroderma patients, together with MCTD ... Dermatomyositis: an inflammatory disease of skin and muscle marked especially by muscular weakness and skin rash. Scleroderma ...
Epidermolysis bullosa
... is an inherited disease affecting laminin and collagen. This disease is characterized by blister formation within the lamina ... In a survey of 11 families affected by the disease, lack of awareness of the disease by both the public and health care ... DEB is caused by genetic defects (or mutations) within the human COL7A1 gene encoding the protein type VII collagen (collagen ... Epidermis bullosa pruriginosa and albopapuloid epidermolysis bullosa (Pasini's disease) are rare subtypes of this disease. The ...
Relaxin
"Endogenous relaxin regulates collagen deposition in an animal model of allergic airway disease". Endocrinology. 147 (2): 754-61 ... Relaxin may affect collagen metabolism, inhibiting collagen synthesis and enhancing its breakdown by increasing matrix ... Relaxin has been shown to reduce cardiac fibrosis in animal models by inhibiting cardiac fibroblasts secreting collagen and ... An emerging player in human health and disease". Molecular Genetics & Genomic Medicine. 8 (4): e1194. doi:10.1002/mgg3.1194. ...
Anterior spinal artery syndrome
Other causes include vasculitis, polycythemia, sickle cell disease, decompression sickness, and collagen and elastin disorders ...
LASIK
"Laser in situ keratomileusis in patients with collagen vascular disease: a review of the literature". Clinical Ophthalmology. 6 ... Punctal occlusion is accomplished by placing a collagen or silicone plug in the tear duct, which normally drains fluid from the ... Ruiz-Moreno JM, Alió JL (2003). "Incidence of retinal disease following refractive surgery in 9,239 eyes". Journal of ... autoimmune diseases, severe dry eyes, and significant blepharitis should be treated before consideration for LASIK. Women who ...
Oligohydramnios
Conditions such as preeclampsia, chronic hypertension, collagen vascular disease, nephropathy, and thrombophilia cause ... are associated with gastrointestinal abnormalities Congenital abnormalities such as renal agenesis and cystic renal disease are ...
Vesiculobullous disease
"Direct Immunofluorescence Testing in the Diagnosis of Immunobullous Disease, Collagen Vascular Disease, and Vascular Injury ... A vesiculobullous disease is a type of mucocutaneous disease characterized by vesicles and bullae (i.e. blisters). Both ... Linear immunoglobulin-A disease (linear IgA disease) Genetic: Epidermolysis bullosa Some features are as follows: Magro, C. M ... Examples of vesiculobullous diseases include: Infectious: (viral) Herpes simplex Varicella-Zoster infection Hand, foot and ...
Catenin
Spivey KA, Chung I, Banyard J, Adini I, Feldman HA, Zetter BR (October 2011). "A role for collagen XXIII in cancer cell ... MacDonald BT, Tamai K, He X (July 2009). "Wnt/β-catenin signaling: components, mechanisms, and diseases". Dev. Cell. 17 (1): 9- ... For instance, higher levels of collagen XXIII have been associated with higher levels of catenins in cells. These heightened ... levels of collagen helped facilitate adhesions and anchorage-independent cell growth and provided evidence of collagen XXIII's ...
Equine anatomy
Once a tendon is damaged the tendon will always be weaker, because the collagen fibres tend to line up in random arrangements ... Diseases and surgery of the globe and orbit". In Gilger, BC (ed.). Equine Ophthalmology (3rd ed.). John Wiley & Sons. p. 151. ... As tendons develop they lay down collagen, which is the main structural protein of connective tissue. As tendons pass near bony ...
Topical fluoride
These fluorides in the brain may cause neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and IQ ... SDF, in addition to performing the functions of conventional topical fluorides, is suggested to have collagen-conserving ... These diseases can cause painful responses when associated with the acid or ammonia in SDF. Crystal, Yasmi O.; Niederman, ... Silver diamine fluoride is contraindicated in patients having silver allergy, oral ulcerations and severe gum disease. ...
Fibroblast-like synoviocyte
These cells play a crucial role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis. The inner ... 2010). "Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production". Science. 327 (5965): 580- ... Synovial hyperplasia (an increase in cell number) is a typical feature of the autoimmune disease called rheumatoid arthritis ( ... such as expression of several types of collagens and protein vimentin, a part of cytoskeletal filaments. Unlike fibroblasts, ...
ABL (gene)
Abelson HT, Rabstein LS (August 1970). "Lymphosarcoma: virus-induced thymic-independent disease in mice". Cancer Research. 30 ( ... is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous ... whose expression is down-regulated in Alzheimer's disease". Gene. 271 (2): 159-69. doi:10.1016/S0378-1119(01)00521-2. PMID ...
Senescence
... and increased risk of aging-associated diseases including cancer and heart disease. Aging has been defined as "a progressive ... Chemical damage to structural proteins can lead to loss of function; for example, damage to collagen of blood vessel walls can ... In Wilson's disease, a hereditary defect that causes the body to retain copper, some of the symptoms resemble accelerated ... Dolly the sheep died young from a contagious lung disease, but data on an entire population of cloned individuals would be ...
List of cardiology mnemonics
PAID: Pulmonic & Aortic Insufficiency=Diastolic.p. 32 CARDIAC RIND:p. 34 Collagen vascular disease Aortic aneurysm Radiation ... 31 Depressed ventricular function Unstable angina Stenosis of the left main stem Triple vessel disease WiLLiaM MaRRoW:p. 31 W ... Valve disease Aneurysm of Ventricles Dressler's Syndrome thromboEmbolism (mural thrombus) Recurrence/ mitral Regurgitation DUST ...
Anti-aging product
Epidermal growth factor, to stimulate cell renewal and collagen production in the skin, and strengthen elasticity and structure ... but generally don't provide strong evidence that antioxidant supplements have a substantial impact on disease. Sunscreens ...
Achilles tendinitis
This lack of blood supply can lead to the degradation of collagen fibers and inflammation. Tightness in the calf muscles has ... "Differential diagnosis of diseases of the Achilles tendon. A clinico-sonographic concept". Der Radiologe. 36 (1): 38-46. doi: ... Increased water content and disorganized collagen matrix in tendon lesions may be detected by ultrasonography or magnetic ... is especially important for individuals with chronic Achilles tendinosis which is classified as the degeneration of collagen ...
Mineral (nutrient)
Authors: Nielsen, Forrest H. USDA, ARS Source: Modern nutrition in health and disease / editors, Maurice E. Shils ... et al. ... "Bromine is an essential trace element for assembly of collagen IV scaffolds in tissue development and architecture". Cell. 157 ... Authors: Nielsen, Forrest H. USDA, ARS Source: Modern nutrition in health and disease / editors, Maurice E. Shils ... et al.. ... Interrelations between Essential Metal Ions and Human Diseases. Springer Science & Business Media. p. 349. ISBN 978-94-007-7500 ...
Paleolithic
... coronary heart disease, and cerebrovascular disease, because they ate mostly lean meats and plants and frequently engaged in ... 19 February 2019). "Exceptionally high δ15N values in collagen single amino acids confirm Neandertals as high-trophic level ... It is also unlikely that Paleolithic hunter-gatherers were affected by modern diseases of affluence such as type 2 diabetes, ... collagen samples shed new light on their debated diet". Science Daily. Retrieved 21 February 2019. Wilford, John Noble (18 ...
List of diseases (C)
... hemolytic anemia Cold contact urticaria Cold urticaria Cole carpenter syndrome Coleman-Randall syndrome Colitis Collagen ... Marie-Tooth disease type 1A Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease type 1C Charcot-Marie-Tooth disease ... Marie-Tooth disease type 2C Charcot-Marie-Tooth disease type 2D Charcot-Marie-Tooth disease type 4A Charcot-Marie-Tooth disease ... Tooth disease Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease deafness dominant type Charcot-Marie-Tooth disease ...
Familial thoracic aortic aneurysm
A degenerative breakdown of collagen, elastin, and smooth muscle caused by aging contributes to weakening of the wall of the ... Diseases of the aorta, Genetic disorders by system). ...
Harvey Cantor
Zhao ZS, Granucci F, Yeh L, Schaffer PA, Cantor H. Molecular mimicry by herpes simplex virus-1: Autoimmune disease after viral ... Mobilization of natural killer cells inhibits development of collagen-induced arthritis. Proc Natl Acad Sci USA 2011;108:14584 ... Analysis of the relationship between viral infection and autoimmune disease. Immunity 15:137-147. McCarty N, Paust S, Ikizawa K ...
Koenen's tumor
... and uncommonly in individuals that do not have this genetic disease. One individual with another rare genetic disease that has ... spindle-shaped or star-shaped fibroblasts and ectatic blood vessels in a dense collagen fiber connective tissue background. In ... KTs most commonly develop in individuals who have the rare genetic disease, tuberous sclerosis (a heritable neurocutaneous ... cases associated with tuberous sclerosis, KTs appear to be a result of this disease's associated genetic abnormalies, i.e. loss ...
Integrin alpha 2
Plenz GA, Deng MC, Robenek H, Völker W (2003). "Vascular collagens: spotlight on the role of type VIII collagen in ... "Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: a meta-analysis ... "Platelet receptors for collagen". Thromb. Haemost. 78 (1): 439-44. doi:10.1055/s-0038-1657566. PMID 9198193. Takada Y, Kamata T ... integrin upon release from keratinocytes migrating on type I collagen". J. Biol. Chem. 276 (31): 29368-74. doi:10.1074/jbc. ...
Striated muscle tissue
Coronary artery disease (narrowed coronary arteries) Arrhythmia (irregular heartbeat) Cardiomyopathy (disease of the heart ... The perimysium organizes the muscle fibers, which are encased in collagen and endomysium, into fascicles. Each muscle fiber ...
Trimeric autotransporter adhesin
Bartonella henselae is the causative agent of cat scratch disease, a normally harmless disease, but, in people with a weakened ... Nummelin H, Merckel MC, Leo JC, Lankinen H, Skurnik M, Goldman A (2004). "The Yersinia adhesin YadA collagen-binding domain ... TAAs are just one of many methods bacteria use to infect their hosts, infection resulting in diseases such as pneumonia, sepsis ... The head domain, once assembled, then adheres to an element of the host extracellular matrix, for example, collagen, ...
LECT2
... and may be involved in various diseases. However, LECT2's relationships to these diseases requires much further study before ... mice made deficient in LECT2 using a gene knockout method developed more severe osteoarthritis induced by anti-type II collagen ... It has been suggested that individuals with the disease have an increase in LECT2 production and/or a decrease in LECT2 ... Furthermore, its levels in these tissues often change as a function of various diseases. These findings indicate that LECT is ...
Flaccid dysarthria
Medical treatments may include surgery such as medialization laryngoplasty; arytenoid adduction; or, fat/collagen injections. ... Demyelinating disorders Infectious/Inflammatory Degenerative disorders Metabolic Neoplastic Traumatic Vascular Diseases Flaccid ...
Sprain
Collagen fibers have about a 4% elastic zone where fibers stretch out with increased load on the joint. However, exceeding this ... US National Institute of Arthritis and Musculoskeletal and Skin Diseases Wikimedia Commons has media related to Sprains. ( ... Ligaments are tough, inelastic fibers made of collagen that connect two or more bones to form a joint and are important for ... Chronic sprains are caused by repetitive movements leading to overuse.[citation needed] Ligaments are collagen fibers that ...
Integumentary system
Substantial collagen bundles anchor the dermis to the hypodermis in a way that permits most areas of the skin to move freely ... Possible diseases and injuries to the human integumentary system include: Rash Yeast Athlete's foot Infection Sunburn Skin ... It invaginates into the dermis and is attached to the latter, immediately above it, by collagen and elastin fibers. It is ... It is composed of dense irregular connective tissue and areolar connective tissue such as a collagen with elastin arranged in a ...
WWC1
Studies have also begun to investigate the role of KIBRA in Alzheimer's disease. KIBRA has at least 10 interaction partners, ... "KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling". Biochim. Biophys. Acta. 1783 (3): ... "Brain Protein Linked To Alzheimer's Disease". ScienceDaily (Press release). September 16, 2008. Schneider A, Huentelman MJ, ... "Evidence for an association between KIBRA and late-onset Alzheimer's disease". Neurobiol. Aging. 31 (6): 901-9. doi:10.1016/j. ...
Liposuction
Referred to as Smart Lipo, this technique uses laser technology to coagulate and tighten the skin and boost collagen ... 2010). Microcannular tumescent liposuction in advanced lipedema and Dercum's disease. Giornale italiano di dermatologia e ... and halt disease progression. Only small blunt cannulas are used, great care is used to not injure lymphatic which are already ... and this condition has been linked to life-shortening diseases such as diabetes, stroke, and heart attack. There are two ...
INPP5D
On the other hand, its low activity leads to autoinflammatory diseases. This knowledge is used in drug development. In the case ... is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous ... of autoinflammatory diseases, there is an attempt to increase SHIP1 catalytic activity by binding the small molecule to the C2 ...
AP-1 transcription factor
Stark CJ, Atreya CD (April 2005). "Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies ... "Glycated albumin stimulation of PKC-beta activity is linked to increased collagen IV in mesangial cells". The American Journal ...
Liver support system
... pathophysiology and treatment of these diseases Evaluate the clinical impact of MARS therapy on the course of the disease in ... Hepatocytes are suspended in a gel solution such as collagen, which is injected into a series of hollow fibers. In the case of ... Kim WR, Gross JB Jr, Poterucha JJ, Locke GR 3rd, Dickson ER (Jan 2001). "Outcome of hospital care of liver disease associated ... On the other hand, a patient with a chronic hepatic disease can suffer an acute decompensation of liver function following a ...
Glaucoma
Sometimes, the disease appears very rapidly, especially after cataract surgery procedures. A new treatment for this disease, as ... such as the Aquaflow collagen wick, ologen Collagen Matrix, or Xenoplast glaucoma implant. Laser-assisted NPDS is performed ... Glaucoma is a group of eye diseases that result in damage to the optic nerve (or retina) and cause vision loss. The most common ... "Glaucoma". Parsons' diseases of the eye (22nd ed.). Elsevier. 15 July 2015. pp. 288-295. ISBN 978-81-312-3818-9. Salmon JF. " ...
Penis enlargement
Penis reduction Peyronie's disease Plastic surgery Tissue expansion Oderda M, Gontero P (April 2011). "Non-invasive methods of ... Tealab AA, Maarouf AM, Habous M, Ralph DJ, Abohashem S (June 2013). "The use of an acellular collagen matrix in penile ... Chung E, Brock G (February 2013). "Penile traction therapy and Peyronie's disease: a state of art review of the current ... Usta MF, Ipekci T (June 2016). "Penile traction therapy for Peyronie's disease-what's the evidence?". Translational Andrology ...
Collagen vascular disease: MedlinePlus Medical Encyclopedia
Some of these diseases are similar to each other. They may involve arthritis and inflammation of ... In a class of diseases known as autoimmune disorders, the bodys immune system attacks its own tissues. ... People who developed these disorders were previously said to have "connective tissue" or "collagen vascular" disease. We now ... In a class of diseases known as autoimmune disorders, the bodys immune system attacks its own tissues. Some of these diseases ...
Serval - Restriction Fragment Length (RFL) Analysis of the Gene for Cartilege-Specific Type-II Collagen in Kniest Disease
Restrictive Lung Disease Treatment & Management: Medical Care, Surgical Care, Consultations
Unlike obstructive lung diseases, including asthma and COPD, which show a normal or increased total lung capacity (TLC), ... either because of an alteration in lung parenchyma or because of a disease of the pleura, chest wall, or neuromuscular ... Restrictive lung diseases are characterized by reduced lung volumes, ... Collagen-vascular disease. Therapy for pulmonary fibrosis associated with collagen-vascular disease is controversial because ...
homeopathy | ScienceBlogs
DailyMed - PREDNISONE tablet
Collagen Diseases During an exacerbation or as maintenance therapy in selected cases of: systemic lupus erythematosus, systemic ... Gastrointestinal Diseases To tide the patient over a critical period of the disease in: ulcerative colitis, regional enteritis. ... More severe disease states usually will require daily divided high dose therapy for initial control of the disease process. The ... usually four to ten days in the case of many allergic and collagen diseases. It is important to keep the period of initial ...
Collagen vascular disease: Care Locations | UF Health, University of Florida Health
Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease...
Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease ... Renal diseases. * Renal diseases. Learn more about how our renal biomarkers can provide value in your clinical program. ... Hepatic diseases. * Hepatic diseases. Learn more about how our hepatic biomarkers can provide value in clinical program. ... Respiratory diseases. * Respiratory Diseases. Learn more about how our respiratory biomarkers can provide value in your ...
Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission...
METHODS: Six-week-old male DBA/1 mice were immunized with murine type II collagen in Freunds complete adjuvant, resulting in a ... Anti-IL-12 treatment initiated after the onset of clinical symptoms accelerated disease. Pulse therapy with anti-CD3 plus anti- ... CONCLUSION: Chronic relapsing homologous collagen-induced arthritis is a valuable model for identifying remission-inducing ... To test whether the chronic relapsing arthritis induced by immunizing DBA/1 mice with homologous type II collagen is a valuable ...
Radiologic Patterns of Lung Disease | NIOSH | CDC
Radiologic patterns of lung disease associated with occupational exposures on chest radiograph and chest CT. ... Collagen vascular disease. Smoking-related lung disease. Ground-glass opacity. Hypersensitivity pneumonitis. Acute or subacute ... Obliterative bronchiolitis related to collagen vascular disease, previous infection, etc.. Pleural thickening/plaques. ... Chronic beryllium disease. Smoking-related lung disease. Drug toxicity. Pulmonary hemorrhage. Aspiration. ...
Glycobiology and Extracellular Matrices
... of the α345 hexamer of collagen IV present in patients with glomerular basement membrane diseases, Goodpastures disease and ... Collagen IVα345 dysfunction in glomerular basement membrane diseases. II. Crystal structure of the α345 hexamer. Journal of ... Collagen IVα345 dysfunction in glomerular basement membrane diseases. III. A functional framework for α345 hexamer assembly. ... Collagen IVα345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial ...
IMSEAR at SEARO: BIOCHEMICAL STUDY ON COLLAGEN DISEASES OF THE SKIN BY AMINO ACID PAPER CHROMATOGRAPHY.
Clinically isolated syndrome in collagen diseases; approaches and treatments | Arthritis Research & Therapy | Full Text
Naproxen (Aleve) - Side Effects, Interactions, Uses, Dosage, Warnings | Everyday Health
Chronic kidney disease affects an estimated 37 million people in the US. If caught and treated early, serious problems can be ... Collagen Vascular Disease. *Autoimmune Disorder. *Feltys Syndrome. *Rheumatoid Lung. *Juvenile Rheumatoid Arthritis ... heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; ... Innovative system reveals a pair of potential therapies for autosomal recessive polycystic kidney disease, which currently has ...
Human Diseases and Conditions - Gale - Literati by Credo
Human Diseases and Conditions, 3rd ed. offers current and accurate information on approximately 450 diseases and conditions. ... Offering in-depth coverage of all areas of health and disease, ... Collagen Vascular Diseases: Overview. *Collapsed Lung ( ... Human Diseases and Conditions. Human Diseases and Conditions. Editors: Gale. Publication Year: 2017. Publisher: Gale. ... Offering in-depth coverage of all areas of health and disease, Human Diseases and Conditions, 3rd ed. offers current and ...
Table 1 - Clonal Expansion of Multidrug-Resistant Streptococcus dysgalactiae Subspecies equisimilis Causing Bacteremia, Japan,...
Collagen diseases. 8 (6.0). Chronic lung diseases. 7 (5.3). HIV. 0. Chemotherapy. 12 (9.0). ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... the Centers for Disease Control and Prevention, or the authors affiliated institutions. Use of trade names is for ...
Dilated Cardiomyopathy: Practice Essentials, Background, Pathophysiology
Dilated cardiomyopathy is a progressive disease of heart muscle that is characterized by ventricular chamber enlargement and ... Cardiomyopathy associated with collagen-vascular disease. Several collagen-vascular diseases have been implicated in the ... Other infiltrative diseases that resemble hypertrophic/hypertensive heart disease include Danton disease, Friedreich ataxia, ... As with other diseases, authorities depend on reported cases (at necropsy or as a part of clinical disease coding) to define ...
Familial Mediterranean Fever - GeneReviews® - NCBI Bookshelf
Inflammatory bowel disease [Cattan et al 2000, Beşer et al 2013] including Crohn disease, which is more common, presents ... GeneReviews staff has selected the following disease-specific and/or umbrella support organizations and/or registries for the ... Autoinflammatory diseases *. Cryopyrin-associated periodic syndromes (CAPS) include: chronic infantile neurologic cutaneous and ... Crohn disease (OMIM 260920) can present with low-grade fever and abdominal pain. It is not typically associated with FMF, but ...
Exploratory Study of the Efficacy and Safety of Juvista 250ng When Administered Following Excision of Ear Lobe Keloids - Full...
Bruttini M[au] - Search Results - PubMed
NIOSHTIC-2 Search Results - Full View
Lung disorders; Respiratory diseases; Collagen fibrils; Pulmonary disorders; Animal studies; Fibrosis. CODEN. ... The use of oxygen therapy and drugs early in the course of the disease, smoking, intercurrent disease, and genetic variability ... In addition to measuring collagen accumulation in the lungs, we investigated the effects on collagen crosslinking, a ... which interfere with proper folding of collagen, or beta-aminopropionitrile, which interferes with collagen crosslinking. We ...
Prognosis of Interstitial Pneumonia With Autoimmune Features
Fast Five Quiz: Systemic Sclerosis Interstitial Lung Disease * 20021343513-overview. Diseases & Conditions Collagen Tissue ... IgG4-related disease, eosinophilic pneumonia, Langerhans cell histiocytosis, and acute interstitial pneumonia. ... IgG4-related disease, eosinophilic pneumonia, Langerhans cell histiocytosis, and acute interstitial pneumonia. ... "undifferentiated connective tissue disease") (Supplementary Figure 2, https://links.lww.com/RHU/A454). ...
Interstitial Lung Disease
Skin care: 5 tips for healthy skin - Mayo Clinic
Smoking also damages collagen and elastin - the fibers that give your skin strength and elasticity. In addition, the repetitive ... Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions. ... https://www.aad.org/public/diseases/dry-sweaty-skin/dry-skin. Accessed Oct. 12, 2017. ...
Jesús COSÍN-ROGER | Investigador Miguel Servet | BSc, MSc, PhD Biomedicine and Pharmacology | Hospital Universitario Doctor...
P056 Crohns Disease associated fibrosis modulates the expression of collagen receptors. Article ... Background: Inflammatory bowel diseases (IBD), Crohns disease (CD) and ulcerative colitis (UC), are typically associated with ... Background: Inflammatory bowel diseases (IBD), Crohns disease (CD) and ulcerative colitis (UC), are typically associated with ... in the VDR gene have been related to inflammatory bowel disease. Indeed, Crohn′s disease (CD) patients carrying th... ...
Advanced Search Results - Public Health Image Library(PHIL)
Categories: Collagen Diseases Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ...
Is It Menopause or Something Else? - HealthyWomen
Collagen vascular diseases. Collagen vascular diseases occur when the bodys immune system attacks its own tissues and organs. ... "If somebody is hot and achy, it could be menopause, but it also could be collagen vascular disease," Minkin said. ... "Hodgkins disease and non-Hodgkin lymphoma are the classics, but several other cancers can do it," Minkin said. ... Some of these diseases, including lupus and rheumatoid arthritis, can look like menopause. " ...
Nelson Pediatrics Board Review, 1st Edition - 9780323530514
Home - Professor Roger Greenhalgh
Influence of type III collagen genotype on aortic diameter and disease.. Br J Surg 1993: 80(10), 1246-1248 ... Modern Trends and Vascular Disease - Peripheral arterial disease. Trans Med Soc London 1982-84: 99-100, 111 113 ... Use of small bowel imaging for the diagnosis and staging of Crohns disease--a survey of current UK practice.. Br J Radiol 84( ... The influence of collagen and albumen presealants on knitted Dacron grafts.. Eur J Vasc.Surg 1993: 7(3), 271-276 ...
Vascular DiseasesPeptidesChronic obstrucElastinRheumatoidPulmonaryAutoimmune DiseasesFibersCongenitalMice with collagen-inducedSystemicProteinConnectiveElasticitySynthesisOsteoarthritisCardiovascularBlood vesselFragments of collagenBenefits of collagenFormation of collagenArthritisDermisBoneSecretionBovineMarine collagenFibroblastsFibrosisCenters for DiseasFibroticHereditaryBody'sOrgansDisordersClinicallyProteinsHeterogeneous groupLung diseasesDisorderDietaryDegenerativeExtracellularHypersensitivityAcuteInflammatory Bowel DPowderGastrointestinal DiseasesSkinSymptomsMuscularPathogenicInflammationFibroblastChondroitinAmino acidsAshwagandhaClinicalLesionsDiagnosisTypeRenalCrohn's Disease
Vascular Diseases7
- Collagen vascular diseases occur when the body's immune system attacks its own tissues and organs. (healthywomen.org)
- Each of these types of vascular diseases has its own unique set of symptoms, risk factors , and treatment options. (bannerhealth.com)
- Underlying causes of these fevers are difficult to diagnose, but proposed causes are infections, cancers and collagen-vascular diseases. (news-medical.net)
- SCLS was also detected in 33 patients with idiopathic pulmonary fibrosis (IPF) and nine of 23 with collagen vascular diseases (CVD). (cdc.gov)
- Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood levels of potassium, severe dehydration (and loss of electrolytes such as sodium), blood vessel disease (e.g., collagen vascular diseases such as lupus, scleroderma). (canadianmopharmacy.com)
- These include individuals with a strong family history (more than one first degree relative with brain aneurysm), or a history of certain conditions such as polycystic kidney disease or collagen vascular diseases. (kili2017.com)
- Vitamin D3: Plays a key role in bone and muscle health, calcium breakdown, immune system function and helps fight colon cancer and vascular diseases. (thebigcarrot.ca)
Peptides39
- Hydrolyzed Type 1 & 3 Collagen Peptides, Grass Fed, Pasture Raised Bovine. (eatyournutrition.com)
- 10 grams of collagen peptides and only 35 calories per serving. (eatyournutrition.com)
- Hydrolyzed collagen peptides provide the amino acids of collagen synthesis in the dermis via increased elastin fiber creation (1,2). (eatyournutrition.com)
- 390 GRAMS (0.86 LBS) Collagen Complete contains a unique blend of three patented collagen peptides supported by clinical research sh. (connorcarrick.com)
- Collagen Complete contains a unique blend of three patented collagen peptides supported by clinical research showing their efficacy for supporting collagen production, bone strength, joint health and integrity, skin elasticity and more. (connorcarrick.com)
- The amino acid composition of dietary collagens are very similar to those in human collagens, making dietary collagen peptides ideal for supporting normal body collagen turnover and renewal. (connorcarrick.com)
- Have you been hearing wonderful things about the benefits of collagen peptides? (young1.life)
- Collagen peptides offer a lot of unique benefits that may not be found in other protein sources that you are currently taking. (young1.life)
- One of the things that have made collagen peptides so popular is the fact that it hydrates the skin from the inside out. (young1.life)
- You can effectively combat the signs of aging with proper hydration of the skin via collagen peptides. (young1.life)
- Scientific studies have shown the Anti-wrinkle benefits of collagen peptides. (young1.life)
- If you're having trouble digesting protein from these sources then collagen peptides can help. (young1.life)
- When you are using collagen peptides to increase your protein intake, make sure you use hydrolyzed collagen peptides as you will have a better chance of digesting them. (young1.life)
- Since protein is such an important nutrient for the body, taking collagen peptides is one of the best ways to ensure that you get the right amounts to stay healthy. (young1.life)
- One of the easiest ways to improve the health of your joints is to start taking collagen peptides . (young1.life)
- If you play sports, or you are elderly, collagen peptides are especially useful for warding off aches and pains in your joints. (young1.life)
- Collagen peptides have been shown to help improve your bone health when you are suffering from this condition. (young1.life)
- Taking collagen peptides has been shown to assist with making nails strong and healthy. (young1.life)
- Collagen peptides have also been shown to assist growing nails significantly in addition to making them strong. (young1.life)
- If you are looking to lose weight quickly then collagen peptides can also assist you with this. (young1.life)
- Collagen peptides can offer appetite control. (young1.life)
- The protein in collagen peptides offers high levels of appetite control. (young1.life)
- The ability to assist you with appetite control makes collagen peptides an ideal companion for any diet plan. (young1.life)
- Taking collagen peptides can significantly aid in preventing a loss of bone mass. (young1.life)
- Additionally, collagen peptides can help with muscle mass as well. (young1.life)
- Taking collagen peptides consistently can help increase your muscle mass. (young1.life)
- Collagen peptides can help you is if you are not sleeping well. (young1.life)
- Taking collagen peptides can improve the quality of your sleep and reduce the amount of time it actually takes you to fall asleep at night. (young1.life)
- If you have been feeling drowsy during the day because of working long hours or studying, then collagen peptides can help you feel better. (young1.life)
- You can take collagen peptides early in the morning or you can also take them before bed depending on your need for them. (young1.life)
- Collagen peptides may improve your heart health. (young1.life)
- There is some evidence that collagen peptides can help to make your blood vessel walls healthier and reduce the risk that you will develop heart disease. (young1.life)
- If you are trying to increase heart health the best thing you can do is to take some collagen peptides at least twice per day. (young1.life)
- Collagen peptides can help you with the health of your gut. (young1.life)
- If you're currently suffering from leaky gut syndrome and your doctor has told you that your gut health is not good, then taking collagen peptides daily can help. (young1.life)
- However, adding collagen peptides to the mix is a great way to start feeling even better. (young1.life)
- Collagen deficiency is noticeable quite quickly because it is collagen peptides that affect the condition of the skin. (labosal.com)
- A 2008 animal study [4] used marine collagen peptides. (labosal.com)
- MADE WITH VERISOL - Clinically studied Verisol Bioactive Collagen Peptides promote enhanced skin elasticity, promote an increase in skin collagen by as much as 60%, and support reduction of depth of eye wrinkles. (jaycfoods.com)
Chronic obstruc3
- BACKGROUND: Change in forced expiratory volume in one second (FEV1) is important for defining severity of chronic obstructive pulmonary disease (COPD). (nordicbioscience.com)
- 8 Hundreds of published scientific studies have established a link between leukotrienes and the occurrence of cardiovascular disease9, carcinoma 10-16, arthritis 17-19 , and respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD) 8 . (our-arthritis.com)
- these disorders include chronic obstructive pulmonary disease (COPD), which is the most common cause of for pulmonale. (medscape.com)
Elastin5
- Smoking also damages collagen and elastin - the fibers that give your skin strength and elasticity. (mayoclinic.org)
- Besides hereditary diseases, such as Williams-Beuren syndrome (WBS), which results in reduced elastin synthesis, injuries, aging, or acquired diseases can lead to the degradation of existing elastin fibers. (cell.com)
- The exact mechanism of degeneration is not well characterized, although degradation of elastin and collagen has been clearly shown. (mssm.edu)
- Collagen cross-linking is important for resiliency and elasticity of the collagen and elastin present in all connective tissues and blood vessel walls. (parisvitamin.com)
- The minerals it contains help improve circulation and increase the production of essential proteins like collagen and elastin. (vatadosha.in)
Rheumatoid5
- Some of these diseases, including lupus and rheumatoid arthritis, can look like menopause. (healthywomen.org)
- Background Prokineticin 2 (PK2) manifestation is upregulated in mice with collagen-induced joint disease (CIA), an pet model of arthritis rheumatoid. (exposed-skin-care.net)
- In the light from the varied functions of neutrophils in the introduction of arthritis rheumatoid [20], these email address details are motivating for future research focusing on the precise mechanism from the PK2-PKR1 pathway in the pathogenesis of joint disease with this model. (exposed-skin-care.net)
- rheumatoid arthritis and systemic lupus erythematosus) can develop anemia as a complication of their disease. (mhmedical.com)
- Frankincense extracts have proved effective in patients suffering from rheumatoid arthritis, Crohn's disease, ulcerative colitis and asthma. (our-arthritis.com)
Pulmonary9
- High doses of penicillamine have been used to prevent the accumulation of collagen in hamster and rat models of pulmonary fibrosis. (cdc.gov)
- Usual interstitial pneumonitis (UIP)/idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic pulmonary fibrotic diseases and has the worst prognosis with a mean life expectancy of 3.8 years. (medscape.com)
- The goal of this review article is to provide an overview of the clinical and radiologic diagnosis of UIP/idiopathic pulmonary fibrosis (IPF) and mimickers of the disease with the main goal being ability to answer the question, "Is it IPF or not? (medscape.com)
- These stages do not indicate disease chronicity or correlate with changes in pulmonary function. (radiologyassistant.nl)
- Subpleural curvilinear shadow in interstitial pulmonary diseases. (cdc.gov)
- The prevalence rate of the subpleural curvilinear shadow (SCLS) was examined in several interstitial pulmonary diseases and in asbestos (1332214) workers with normal chest roentgenograms in an effort to analyze the significance of the SCLS in pulmonary asbestos is. (cdc.gov)
- Heart diseases, carcinoma, chronic pulmonary diseases, Alzheimer's disease, pneumonia and influenza are all linked with this enzyme that is produced by our body.1 This enzyme is called 5-lipoxygenase or 5-LOX for short, which, when generated by the body in excessive amounts, gives rise to a whole cascade of dangerous inflammatory reactions. (our-arthritis.com)
- The pathophysiology of cor pulmonale is a result of increased right-sided filling pressures from pulmonary hypertension that is associated with diseases of the lung. (medscape.com)
- Group 5: Pulmonary hypertension caused by other diseases or conditions, including sarcoidosis, polycythemia vera (which can lead to increased blood viscosity and, subsequently, pulmonary hypertension), vasculitis, and other disorders. (medscape.com)
Autoimmune Diseases4
- Astragalus is also specifically use to treat fibrotic changes in the tissues, as can occur with numerous autoimmune diseases, including diabetes, nephritis, hepatitis , arthritis, and dermatitis. (ndnr.com)
- In this case, people develop autoimmune diseases. (supermedical.com)
- They can screen you for other autoimmune diseases and treat them if needed. (supermedical.com)
- Depression is also an emerging risk factor for the development of autoimmune diseases. (supermedical.com)
Fibers4
- The liberated free radicals form bonds between the collagen fibers. (khannainstitute.com)
- Evidence for combined transepidermal elimination of both collagen and elastic fibers. (medscape.com)
- In addition, it is also worth mentioning that the chemical bonds between the individual fibers are much rarer than in pork or beef collagen. (labosal.com)
- Vitamin C is the required coenzyme for two groups of enzymes that catalyze the crosslinking of collagen fibers - lysyl hydroxylases and prolyl hydroxylases. (parisvitamin.com)
Congenital2
- Right-sided ventricular disease caused by a primary abnormality of the left side of the heart or congenital heart disease is not considered cor pulmonale, but cor pulmonale can develop secondary to a wide variety of cardiopulmonary disease processes. (medscape.com)
- Bethlem myopathy (BM) and Ullrich Congenital Muscular Dystrophy (DMCU) result from a mutation in collagen type VI. (bvsalud.org)
Mice with collagen-induced1
- Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis. (ox.ac.uk)
Systemic5
- These are called undifferentiated systemic rheumatic (connective tissue) diseases or overlap syndromes. (medlineplus.gov)
- Despite reporting flaws, there has clearly been an increased incidence of all the neuro/systemic degenerative diseases since World War II and especially since the 1970s with the arrival of previously unheard-of diseases like chronic fatigue syndrome and AIDS . (bibliotecapleyades.net)
- Ironically enough, it was this systemic inflammatory reaction caused by 5-lipoxygenase that protected our ancestors from infective diseases. (our-arthritis.com)
- Kyrle disease perhaps is most important as a cutaneous sign of a systemic disorder, although idiopathic cases without associated systemic disease occur. (medscape.com)
- The factors that might have influenced these results were systemic condition (DM2), level of oral hygiene, and age, which justifies the high rate of periodontal disease and tooth loss in these individuals. (bvsalud.org)
Protein9
- The type VI collagen is an extracellular protein forming a distinct myofibrillar network of most interstitial connective tissues, existing in the cellular matrices of muscle, skin, tendon, cartilage, intervertebral discs, blood vessels and eyes. (bvsalud.org)
- Collagen is a special type of protein that accounts for as much as 30% of the body's total protein. (connorcarrick.com)
- Despite collagen being the most abundant protein in the body, we are incapable of absorbing it by ourselves. (healthgeekz.net)
- Marine collagen is high in protein, and has zero carbs so fits perfectly within the perimeters of the ketogenic diet. (kollmarine.com)
- In diet and supplementation, collagen plays an important role - a complete protein with a high content of amino acids (including glycine or proline), which is a fundamental element of connective tissue. (labosal.com)
- The lack of collagen protein in the skin contributes to i.a. to the deterioration of its elasticity, problems with proper hydration and an increased tendency to dry out or a decrease in its firmness. (labosal.com)
- C-reactive protein is considered one of the best measures of the acute phase response to an infectious disease or other cause of tissue damage and inflammation. (cdc.gov)
- The patients' levels of protein C, antithrombin III and in vitro platelet aggregation in response to collagen were compared with those of 20 controls. (who.int)
- It usually develops when changes in fat and collagen (a fiber-like protein in your body) happen beneath the skin's surface. (cdc.gov)
Connective4
- People who developed these disorders were previously said to have "connective tissue" or "collagen vascular" disease. (medlineplus.gov)
- 10 of whom had an MDD diagnosis of "undifferentiated connective tissue disease") (Supplementary Figure 2, https://links.lww.com/RHU/A454 ). (medscape.com)
- It is not difficult to guess that the condition of the skin depends on the condition of the connective tissue, which is affected by the amount of collagen. (labosal.com)
- Foremost, it is essential for the synthesis of collagen and glycosaminoglycans which are the building materials of all connective tissues, such as skin, blood vessels, tendons, joint cartilage and bone. (parisvitamin.com)
Elasticity2
- Collagen type III are vital for blood vessel elasticity thus optimizing stroke volume (blood flow), lowered blood pressure (1, 2). (eatyournutrition.com)
- As a result, a complex network of collagen strands is formed, providing elasticity and resiliency. (parisvitamin.com)
Synthesis4
- Silicon may improve skin, hair and nail growth through collagen synthesis. (natureprovides.com)
- Collagen Forte, provided by Douglas Laboratories, supplies significant amounts of Vitamin C, L-Lysine, and LProline in capsule form to help support healthy collagen synthesis. (parisvitamin.com)
- INDICATIONS Collagen Forte may be a useful dietary supplement for individuals wishing to support proper collagen synthesis in the body. (parisvitamin.com)
- Periodontal diseases include a and organs, causing the decrease of collagen heterogeneous group of immunoinflammatory synthesis and chemotaxis, change in growth factors, changes from the host response to bacterial plaque increase of apoptosis and oxidative stress, decrease and its products, and they are among the most of extracellular matrix, deregulation of cytokines, prevalent oral diseases. (bvsalud.org)
Osteoarthritis4
- The paper also discusses the challenges for developing good quality outcome measures for use in large scale multicentre clinical trials for new osteoarthritis treatments, especially disease modifying osteoarthritis drugs. (bmj.com)
- 3 As a cause of disability (such as walking and stair climbing) in the elderly in the west, osteoarthritis is second only to cardiovascular disease. (bmj.com)
- Altogether 10%-15% of adults over 60 have some degree of osteoarthritis, and with an ageing population it is becoming an increasingly important disease. (bmj.com)
- Traditionally, osteoarthritis was viewed as an inevitably progressive, degenerative disease process. (bmj.com)
Cardiovascular6
- A similar elevation in risk was observed for deaths from cardiovascular disease. (lifeextension.com)
- It may also be used as protection against cardiovascular diseases. (vedantu.com)
- As a result, it prevents deadly cardiovascular diseases and boosts blood circulation. (healthgeekz.net)
- Peppers reduce the risk of cardiovascular disease. (magicandbeauty.blog)
- Tomato prevents the occurrence of cardiovascular and eye diseases. (magicandbeauty.blog)
- A growing body of evidence has identified fibrinogen as an important risk factor for cardiovascular disease, the major cause of death in the U.S. The objective of including this measure is to provide data on laboratory, clinical, and socio- demographic correlates of fibrinogen levels. (cdc.gov)
Blood vessel1
- Fish is excellent in the prevention of heart and blood vessel diseases and the preservation of the nervous system. (magicandbeauty.blog)
Fragments of collagen2
- Matrix metalloproteinase (MMP)-generated fragments of collagen type I, and type VI (C1M and C6M) were assessed in month six serum samples. (nordicbioscience.com)
- What is the role of peptide fragments of collagen I and IV in health and disease? (eatyournutrition.com)
Benefits of collagen1
- Complete Collagen+ comes with all the benefits of collagen which effectively reverses aging problems and increases confidence levels. (healthgeekz.net)
Formation of collagen2
- It is used in hair care products as it helps in the formation of collagen in the body, and collagen is an essential substance that promotes healthy and thick hair growth. (vedantu.com)
- Vitamin C plays a vital role in the formation of collagen, the main support system of the skin. (homeremedieslog.com)
Arthritis7
- Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission-inducing therapies. (ox.ac.uk)
- OBJECTIVE: To test whether the chronic relapsing arthritis induced by immunizing DBA/1 mice with homologous type II collagen is a valuable model for testing disease-modifying antiarthritic drugs. (ox.ac.uk)
- CONCLUSION: Chronic relapsing homologous collagen-induced arthritis is a valuable model for identifying remission-inducing antiarthritic drugs and has predictive value with respect to their joint-protective potency. (ox.ac.uk)
- Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells. (ox.ac.uk)
- 2-5 Scientists have been familiar with this enzyme for some time due to its role in occurrence of arthritis, asthma and Crohn's disease, which is why the pharmaceutical industry aims to develop a safe drug to alleviate the effect of 5-lipoxygenase. (our-arthritis.com)
- Therefore, we could just as well entitle this article "treating arthritis and all other inflammatory degenerative disease conditions" because the approach is fundamentally always the same. (healthfully.net)
- There is an obvious difficulty in overcoming any state of disease, especially one like arthritis. (healthfully.net)
Dermis3
- There may be mucin deposition in the dermis, hemorrhage around blood vessels, streaking of collagen on the sides of the dermal papillae. (renalandurologynews.com)
- SUPPORTS CELL PROTECTION - Skin supporting Vitamin C protects skin from cell-damaging free radicals and helps collagen formation in the dermis layer. (jaycfoods.com)
- informative epidemiological studies of the role of Similarly there appears to be a reduced amount indoor tanning facilities in the induction of photo- of collagen I in the dermis and increased ageing. (who.int)
Bone6
- Shannon has one of the more severe forms of osteogenesis imperfecta , also known as "brittle bone disease," a rare disorder that weakens collagen, bones and other parts of the body. (kennedykrieger.org)
- Collagen oligopeptides (ligands) attach to fibroblasts (bone formation cells) receptors on the fibroblast membrane synthesizing new collagen production (1,2,3). (eatyournutrition.com)
- Biological effect of hydrolyzed collagen on bone metabolism. (eatyournutrition.com)
- Chronic graft versus host disease (cGVHD) is the most common consequence of allogeneic bone marrow transplantation, and it is associated with morbidity and mortality. (bvsalud.org)
- Muscle tissue is also made up of collagen and similar to bone mass it can deteriorate. (young1.life)
- 2018). the junctional and sulcular epithelium for the The relationship of diabetes - both types 1 periodontal pocket epithelium, as well as episodes and 2 - with oral and periodontal diseases and its of conjunctive attachment loss and alveolar bone influence on oral pathologies are evident. (bvsalud.org)
Secretion1
- Tomato is rich in lycopene which stimulates collagen secretion. (magicandbeauty.blog)
Bovine5
- Our multi-collagen is from grass fed, pasture raised bovine. (eatyournutrition.com)
- Full Body combines the power of Bovine Collagen & Ashwagandha Root to promote a healthy, mobile body while managing the stress that may come along with an active life. (thefitinbedstuy.com)
- Over the years, the most commonly used raw materials have been bovine collagen. (labosal.com)
- Marine Collagen or Bovine Collagen - what to choose? (labosal.com)
- Although bovine collagen is characterized by high stability and density, its large molecules and chaotic chemical structure mean that it does not show sufficient biological activity. (labosal.com)
Marine collagen8
- And is marine collagen compatible with the diet? (kollmarine.com)
- Marine Collagen and other forms of collagen - what is worth choosing? (labosal.com)
- The development of science has meant that marine collagen is mentioned more and more often, which has been used, among others, in the dietary supplement Labosal Beauty Shot . (labosal.com)
- The main reason for choosing marine collagen is its high bioavailability. (labosal.com)
- Marine collagen proteins are in the form of a triple helix [3], which means that it is extremely similar to the collagen found in human skin. (labosal.com)
- In the context of beauty and the fight against imperfections, the best choice will be preparations containing marine collagen proteins. (labosal.com)
- As a result, marine collagen was found to have protective properties against simulated skin aging. (labosal.com)
- Equally interesting results were observed in a study conducted in 2021 [6], which concerned the effectiveness of supplementation with hydrolyzed marine collagen in women between 45 and 60 years of age. (labosal.com)
Fibroblasts2
- After 90 days of treatment, it turned out that the use of fish collagen improved the antioxidant effect, and also led to an increase in skin thickness and the number of fibroblasts. (labosal.com)
- During formation of new collagen, fibroblasts secrete immature collagen strands and a vitamin C- and copper-requiring enzyme, lysyl oxidase. (parisvitamin.com)
Fibrosis5
- A retrospective cohort study found that treatment of gastroesophageal reflux disease was associated with an increased length of survival and reduced radiographic evidence of fibrosis. (medscape.com)
- For example, Riley et al have prevented fibrosis in animal models by administering either proline analogues, which interfere with proper folding of collagen, or beta-aminopropionitrile, which interferes with collagen crosslinking. (cdc.gov)
- Background: Fibrosis is a common complication of Crohn's disease (CD) in which macrophages play a central role. (researchgate.net)
- Background Crohn′s disease (CD) is often complicated by the appearance of intestinal stenosis (B2 behaviour) or fistulas (B3 behaviour), and the factors determining the pattern of disease and the etiology of these lesions, both associated with fibrosis and requiring surgery, are poorly defined. (researchgate.net)
- Children who appear malnourished may be suffering from a number of medical conditions that affect their ability to grow and gain weight, including the following: inborn errors of metabolism, growth hormone deficiency , cystic fibrosis , anorexia nervosa , formula intolerance or food allergy , gastrointestinal disorders ( gastroesophageal reflux , celiac sprue , Crohn disease ), or HIV . (logicalimages.com)
Centers for Diseas3
- Centers for Disease Control and Prevention. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
Fibrotic2
- However, from a clinically pragmatic standpoint, one would like to be able to intervene after the fibrotic collagen is present in the lung. (cdc.gov)
- When workers inhale crystalline silica, the lung tissue reacts by developing fibrotic nodules and scarring around the trapped silica particles [Silicosis and Silicate Disease Committee 1988]. (cdc.gov)
Hereditary2
- Alport Syndrome (AS) is a hereditary disease caused by mutations in collagen type IV. (asn-online.org)
- Various leukoencephalopathies, metabolic, hereditary and degenerative diseases are in the differential and have to be screened for and ruled out systematically. (braindiseases.blog)
Body's5
- In a class of diseases known as autoimmune disorders , the body's immune system attacks its own tissues. (medlineplus.gov)
- Lupus is a disease in which the body's immune system attacks itself. (rxwiki.com)
- The body mostly requires it as it produces substances like collagen, adrenaline and dopamine, which help maintain the body's proper functioning. (vedantu.com)
- Unfortunately, with age, the amount of collagen produced decreases in relation to the body's needs. (labosal.com)
- Vitamins D3, B12 and B6: In Neotol Collagen Joint Health help insure the proper functioning of the body's interconnected systems to allow the other ingredients in Neotol Collagen Joint Health to have their maximum effect in repairing joint cartilage, eliminating joint pain and restoring joint function. (thebigcarrot.ca)
Organs3
- Prednisone frequently treats diseases of these organs by reducing inflammation. (rxwiki.com)
- It is only by creating, fostering and maintaining the biochemical, hormonal and physiological conditions under which the organism has the ability to clean, repair and rebuild its cells, tissues and organs that disease conditions-no matter what they are-can be prevented, overcome, reversed and recovered from. (healthfully.net)
- The name scleroderma means 'hard skin'-a simple description of a complex disease that causes thick, hard scar tissue to form either on the outer skin or inside the body around major organs. (medlineplus.gov)
Disorders3
- The aim of this paper is to review the literature and identify orofacial manifestations of hematological diseases, with particular reference to anemias and disorders of hemostasis. (ijdr.in)
- Orofacial petechiae, conjunctivae hemorrhage, nose-bleeding, spontaneous and post-traumatic gingival hemorrhage and prolonged post-extraction bleeding are common orofacial manifestations of inherited hemostatic disorders such as von Willebrand's disease and hemophilia. (ijdr.in)
- orofacial diseases AND anaemic disorders. (ijdr.in)
Clinically2
- One third have continuing disease leading to clinically significant organ impairment. (radiologyassistant.nl)
- Of particular importance in NHANES, the data will be used to study the relationship between fibrinogen levels and clinically measured lower extremity arterial blood flow as assessed by the Ankle-Brachial Index in the Lower Extremity Disease component. (cdc.gov)
Proteins4
- However, it is worth knowing that in the group of collagen proteins, there are as many as 28 different proteins - in the context of skin health and condition, the most important role is played by collagen types I (80% content) and III (about 15% content). (labosal.com)
- Proteins of animal origin are used in dietary supplements containing collagen. (labosal.com)
- The high level of bioavailability of fish collagen proteins is due to the fact that its structural structure. (labosal.com)
- Genetic as shown by twin studies the genes that code for specific collagens, interleukin, and other proteins are implicated in the onset of the condition. (perfectbalanceclinic.com)
Heterogeneous group1
- It is a heterogeneous group of diseases characterised by an adaptive response of synovial joints to a variety of environmental, genetic, and biomechanical stresses. (bmj.com)
Lung diseases7
- Corticosteroids, immunosuppressive agents, and cytotoxic agents are the mainstay of therapy for many of the interstitial lung diseases. (medscape.com)
- In this review we present the key findings in the most common interstitial lung diseases. (radiologyassistant.nl)
- There are numerous interstitial lung diseases, but in clinical practice only about ten diseases account for approximately 90% of cases. (radiologyassistant.nl)
- Knowledge of both radiological and clinical appearances of these more common interstitial lung diseases is therefore important for recognizing them in daily practice and including them in the differential diagnosis. (radiologyassistant.nl)
- Some less common interstitial lung diseases will also be presented because their HRCT presentation may be very typical, allowing for a 'spot diagnosis' in selected cases. (radiologyassistant.nl)
- Fortunately only about 10 of these account for about 90% of all diffuse lung diseases, that are assessed by open lung biopsy. (radiologyassistant.nl)
- Knowing the common and also uncommon HRCT-presentations of these frequently encountered diffuse lung diseases is extremely important. (radiologyassistant.nl)
Disorder3
- Sleep apnea is a common but underdiagnosed sleep disorder that is linked to heart disease and other health problems. (healthywomen.org)
- The eye disorder associated with Graves' disease, called Graves' ophthalmopathy (GO), greatly reduces the quality of life in affected patients. (dovepress.com)
- The eye disorder associated with Graves' disease, called Graves' ophthalmopathy (GO) or "thyroid-associated ophthalmopathy", greatly reduces the quality of life in affected patients 1 , 2 and can lead to eye muscle damage and loss of sight. (dovepress.com)
Dietary2
- Unlike the regular collagen supplements as well as most dietary pills, Complete Collagen provides a delicious caramel taste every time you intake. (healthgeekz.net)
- It might seem that the selection of preparation with collagen is not a problem, especially in times of ubiquitous access to dietary supplements. (labosal.com)
Degenerative9
- Degenerative Disc Disease: Causes, Symptoms and Treatments. (perfectbalanceclinic.com)
- While there are many possible causes, one of the most common is degenerative disc disease. (perfectbalanceclinic.com)
- Furthermore, pain from degenerative disc disease is more likely to occur in people aged between 30 and 50 than it is in people aged 60 or older, as by the time people reach 60 the condition tends to have stabilised, a process that can take 20 to 30 years. (perfectbalanceclinic.com)
- There are several causes of degenerative disc disease. (perfectbalanceclinic.com)
- There is also a relationship between degenerative disc disease and smoking which is thought to relate to reduced blood flow to the disc. (perfectbalanceclinic.com)
- Sometimes other conditions can give similar symptoms to degenerative disc disease. (perfectbalanceclinic.com)
- Self-care is an important factor especially as when properly managed the pain associated with degenerative disc disease generally decreases as we grow older. (perfectbalanceclinic.com)
- For most people, the best way of managing degenerative disc disease is through exercise and physical therapy. (perfectbalanceclinic.com)
- If the white matter is examined under the microscope, degenerative (ischemic) changes are visualized in the small blood vessels hence the term ischemic microvascular small vessel disease is sometimes used. (braindiseases.blog)
Extracellular3
- Collagen IV scaffold is a principal component of the basement membrane (BM), a specialized extracellular matrix that is essential for animal multicellularity and tissue evolution. (jbc.org)
- The obvious target for such an approach is the biosynthesis and extracellular metabolism of the collagen being produced by the injured lung. (cdc.gov)
- In the extracellular matrix, type VI collagen interacts with other components, including collagen type I, collagen type II and collagen type XIV (TAGLIAVINI et al. (bvsalud.org)
Hypersensitivity2
- Cyclosporine has been demonstrated to suppress some humoral immunity and to a greater extent, cell-mediated reactions such as allograft rejection, delayed hypersensitivity and graft vs. host disease. (pediatriconcall.com)
- The immune-modulating properties of Astragalus might be considered to be "amphoteric," meaning that the plant may boost immune responses (thus helping to treat infections and chronic immune issues), as well as reduce immune hypersensitivity in situations of allergy and autoimmune disease. (ndnr.com)
Acute2
- However, CPS intervenes when the child has an acute medical emergency, a life-threatening disease not being treated, or a disease that may result in chronic disability if not treated. (logicalimages.com)
- We present the clinical and laboratory characteristics of acute invasive H. influenzae diseases in children admitted over a 4-year period to a tertiary paediatric ward of the Al-Ain medical district hospital, before vaccination became available in the United Arab Emirates. (who.int)
Inflammatory Bowel D1
- Intestinal microbiota dysbiosis and alterations in the metabolomic profile have been reported in mucosal biopsies from Inflammatory Bowel Disease (IBD) patients. (researchgate.net)
Powder2
- I struggle to take tablets but I found a collagen drink that I like and I open the capsules and mix the powder with the drink and there is no horrible taste. (glucosamine.com)
- I bought Collagen powder and it helped me. (glucosamine.com)
Gastrointestinal Diseases1
- According to the Department of Internal Medicine and Nutritional Sciences Program of the University of Kentucky, high fiber intakes are associated with significantly lower risks of developing coronary heart disease, stroke, hypertension, diabetes, obesity, and certain gastrointestinal diseases. (homeremedieslog.com)
Skin15
- Symptoms of collagen vascular disease will vary but general symptoms include muscle weakness, body aches or joint pain, fatigue, and skin rash. (bannerhealth.com)
- Psoriasis is a disease in which the skin becomes red, irritated, and flaky. (rxwiki.com)
- Inflammatory bacterial skin disease characterized by vesicles, pustules, and crusted-over lesions. (studystack.com)
- COLLAGEN is often taken to support healthy skin, hair,and nails. (eatyournutrition.com)
- Regression of skin lesions of Kyrle's disease with clindamycin: implications for an infectious component in the etiology of the disease. (medscape.com)
- Complete Collagen is a micelle formula collagen supplement by popular cosmetic brand Everbella and helps to facilitate youthful skin, hair, and physique. (healthgeekz.net)
- Complete Collagen components due to the presence of micelles reverses the mechanism thereby producing wholesome and stunning skin, hair, and nails. (healthgeekz.net)
- Misceliized collagen affords thick robust hair and nails, helps quicker muscle recovery, fades wrinkles and different symptoms of growing older main to healthful and stunning skin. (healthgeekz.net)
- In addition, an improper diet, especially one rich in sugar, can accelerate the ageing process of the skin and lead to changes in the structure of collagen [1]. (labosal.com)
- Collagen supplementation may prove to be one of the ways to maintain optimal skin conditions. (labosal.com)
- Fish collagen is perceived as a better biocomponent for human skin than that obtained from pork or beef skin. (labosal.com)
- Lots of people think of collagen as a skin care ingredient due to the fact that it boosts as well as minimizes creases skin health and wellness. (ic-tennis.org)
- Smoking degrades the collagen of your skin causing premature aging, destroys the cells inside your lungs, and promotes heart disease, cataracts and cancer because of the oxidizing radicals released into the blood stream. (youngchiropracticrehab.com)
- The body overproduces collagen, which causes thick, tight patches of skin that stiffen, squeeze, and ultimately damage portions of the body. (medlineplus.gov)
- Some skin diseases are accurately. (who.int)
Symptoms8
- Anti-IL-12 treatment initiated after the onset of clinical symptoms accelerated disease. (ox.ac.uk)
- There are no symptoms of carotid artery disease, but the blockages can lead to a stroke. (bannerhealth.com)
- Symptoms of cerebrovascular disease will vary but commonly include headache, weakness or paralysis of one side, confusion, slurred speech, and loss of vision. (bannerhealth.com)
- If you have questions about the signs or symptoms of vascular disease, treatments, or ways to prevent vascular disease, schedule an appointment with one of the specialists at Banner Health. (bannerhealth.com)
- Notably, signs and symptoms occurring after radiotherapy may not be due to the treatment but to an exacerbation of existing conditions or to the development of new diseases. (nature.com)
- To manage symptoms of an autoimmune disease usually means making lifestyle changes. (supermedical.com)
- I have outlined below the recommended vaccines that cannot prevent transmission of disease either because they are not designed to prevent the transmission of infection (rather, they are intended to prevent disease symptoms), or because they are for non-communicable diseases. (wordpress.com)
- It has also been shown to reduce Al toxicity, improve Alzheimer's Disease symptoms, boost immune function, remineralise bones and improve arterial health. (natureprovides.com)
Muscular2
- The actor who plays the part is John Gluck, who was born with a rare disease called collagen VI muscular dystrophy. (ew.com)
- La Miopatía de Bethlem (MB) y la Distrofia Muscular Congénita de Ullrich (DMCU) son resultados de una mutación en el colágeno VI. (bvsalud.org)
Pathogenic1
- Homozygotes for the p.Met694Val pathogenic variant or compound heterozygotes for p.Met694Val and another disease-causing allele require lifelong treatment with colchicine (1-2 mg/day orally in adults and 0.5-1 mg/day in children according to age and weight). (nih.gov)
Inflammation2
- Multiple sclerosis is a disease in which nerves do not function properly due to inflammation. (rxwiki.com)
- In Neotol Collagen Joint Health MSM works in combination with collagen and chondroitin to reduce joint inflammation and, by reducing joint inflammation, works to reduce joint pain. (thebigcarrot.ca)
Fibroblast1
- Profibrotic growth factors and cytokines contribute directly to fibroblast proliferation and collagen production. (cdc.gov)
Chondroitin2
- In Neotol Collagen Joint Health glucosamine and chondroitin work in combination with collagen to help to rebuild joint cartilage. (thebigcarrot.ca)
- Cartilage is made of water (70%) and a type II collagen framework with proteoglycans and glycosaminoglycans (consisting mainly of aggrecan and also chondroitin), produced by chondrocytes. (bmj.com)
Amino acids1
- Collagen Complete can be incorporated into shakes, smoothies, and other foods and beverages, making it a convenient way to ensure appropriate intake of collagen's unique amino acids. (connorcarrick.com)
Ashwagandha1
- Ashwagandha can be used by anyone who wants to boost his immune system and keep diseases at bay. (vatadosha.in)
Clinical3
- In addition to measuring collagen accumulation in the lungs, we investigated the effects on collagen crosslinking, a potentially more sensitive index of clinical efficacy. (cdc.gov)
- Clinical manifestations of chronic GVHD are similar to autoimmune collagen vascular disease and the two main types of cutaneous chronic GVHD are lichenoid and sclerodermatous. (bvsalud.org)
- This is a cross-sectional clinical study performed with type 2 diabetes mellitus patients and non- diabetic patients, in the city of Passo Fundo, RS, Brazil, which aimed to verify whether periodontal disease is more prevalent in type 2 diabetes mellitus (DM2) patients. (bvsalud.org)
Lesions1
- UV light therapy is considered by some authorities to be the most effective treatment for acquired perforating dermatosis and is particularly helpful for patients with widespread lesions or coexisting pruritus from renal or hepatic disease. (medscape.com)
Diagnosis2
- Early disease diagnosis leads to improved outcomes for patients. (medscape.com)
- Even as cancer remains a difficult disease to diagnose, often resulting in either poor diagnosis or misdiagnosis, the number of new cancer cases is set to double by 2020. (news-medical.net)
Type4
- No matter which type of vascular disease you may be dealing with, Banner Health is here to support you in your journey to healthy living. (bannerhealth.com)
- Type VI collagen. (bvsalud.org)
- In Neotol Collagen Joint Health Vitamin C works in combination with collagen to stimulate the production of the components of joint cartilage- Aggrecan and Type II Collagen. (thebigcarrot.ca)
- Endostatin is derived from the noncollagenous domain 1 (NC1) at the C-terminus of collagen type XVIII. (who.int)
Renal3
- How this collagen enables GBM to function as a permselective filter and how structural defects cause renal failure remain an enigma. (jbc.org)
- routine treatment of end-stage renal disease, including renal transplantation. (nih.gov)
- Chrysostomou A, Becker G. Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease. (druglib.com)
Crohn's Disease1
- People with psoriasis are more likely to have Crohn's disease , pemphigus, vitiligo, and others. (supermedical.com)