Colitis ulcerative. Medical search

Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.

Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.

A condition characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. This syndrome was first described in 1980 by Read and associates. Subtypes include COLLAGENOUS COLITIS and LYMPHOCYTIC COLITIS. Both have similar clinical symptoms and are distinguishable only by histology.

Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.

A subtype of MICROSCOPIC COLITIS, characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. Microscopic examination of biopsy samples taken from the COLON show larger-than-normal band of subepithelial COLLAGEN.

The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.

A reagent that is used to neutralize peptide terminal amino groups.

A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.

Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)

The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.

A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)

A hemeprotein from leukocytes. Deficiency of this enzyme leads to a hereditary disorder coupled with disseminated moniliasis. It catalyzes the conversion of a donor and peroxide to an oxidized donor and water. EC 1.11.1.7.

Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.

Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)

A surgical procedure involving the excision of the COLON and RECTUM and the formation of an ILEOANAL RESERVOIR (pouch). In patients with intestinal diseases, such as ulcerative colitis, this procedure avoids the need for an OSTOMY by allowing for transanal defecation.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Endoscopic examination, therapy or surgery of the luminal surface of the colon.

DYSENTERY caused by intestinal amebic infection, chiefly with ENTAMOEBA HISTOLYTICA. This condition may be associated with amebic infection of the LIVER and other distant sites.

Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.

The insertion of drugs into the rectum, usually for confused or incompetent patients, like children, infants, and the very old or comatose.

An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.

Acute INFLAMMATION in the INTESTINAL MUCOSA of the continent ileal reservoir (or pouch) in patients who have undergone ILEOSTOMY and restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).

Inflammation of the MUCOSA of both the SMALL INTESTINE and the LARGE INTESTINE. Etiology includes ISCHEMIA, infections, allergic, and immune responses.

Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.

An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Sacs or reservoirs created to function in place of the COLON and/or RECTUM in patients who have undergone restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).

Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)

The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.

Live microbial DIETARY SUPPLEMENTS which beneficially affect the host animal by improving its intestinal microbial balance. Antibiotics and other related compounds are not included in this definition. In humans, lactobacilli are commonly used as probiotics, either as single species or in mixed culture with other bacteria. Other genera that have been used are bifidobacteria and streptococci. (J. Nutr. 1995;125:1401-12)

A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.

Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.

The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.

A species of gram-negative bacteria in the genus CITROBACTER, family ENTEROBACTERIACEAE. As an important pathogen of laboratory mice, it serves as a model for investigating epithelial hyperproliferation and tumor promotion. It was previously considered a strain of CITROBACTER FREUNDII.

Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.

Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.

A species of HELICOBACTER that colonizes the CECUM and COLON of several strains of MICE, and is associated with HEPATITIS and carcinogenesis.

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

An acute form of MEGACOLON, severe pathological dilatation of the COLON. It is associated with clinical conditions such as ULCERATIVE COLITIS; CROHN DISEASE; AMEBIC DYSENTERY; or CLOSTRIDIUM ENTEROCOLITIS.

The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.

Immunologic adjuvant and sensitizing agent.

Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.

A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.

A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

A segment of the COLON between the RECTUM and the descending colon.

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)

Endoscopic examination, therapy or surgery of the sigmoid flexure.

Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).

INFLAMMATION of the MUCOUS MEMBRANE of the RECTUM, the distal end of the large intestine (INTESTINE, LARGE).

A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.

Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.

An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.

An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)

Tumors or cancer of the COLON.

Inflammation of the RECTUM and the distal portion of the COLON.

Disease having a short and relatively severe course.

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

Irritants and reagents for labeling terminal amino acid groups.

Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

The passage of viable bacteria from the GASTROINTESTINAL TRACT to extra-intestinal sites, such as the mesenteric lymph node complex, liver, spleen, kidney, and blood. Factors that promote bacterial translocation include overgrowth with gram-negative enteric bacilli, impaired host immune defenses, and injury to the INTESTINAL MUCOSA resulting in increased intestinal permeability. Bacterial translocation from the lung to the circulation is also possible and sometimes accompanies MECHANICAL VENTILATION.

A layer of the peritoneum which attaches the abdominal viscera to the ABDOMINAL WALL and conveys their blood vessels and nerves.

Infections with bacteria of the genus CLOSTRIDIUM.

Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)

A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.

The giving of drugs, chemicals, or other substances by mouth.

Histocompatibility antigens in inflammatory bowel disease. Their clinical significance and their association with arthropathy with special reference to HLA-B27 (W27). (1/3046)

Histocompatibility (HLA) antigen phenotypes have been studied in 100 patients with ulcerative colitis, 100 with Crohn's disease, and 283 normal controls. In addition the incidence of ankylosing spondylitis, sacroiliitis, and "enteropathic" peripheral arthropathy was determined in the patients with inflammatory bowel disease (IBD). There was no significant difference in antigen frequency between patients and controls. However, the incidence of HLA-B27 was increased in the patients complicated by ankylosing spondylitis and/or sacroiliitis in both ulcerative colitis and Crohn's disease. In contrast, none of the 29 IBD patients with "enteropathic" peripheral arthropathy had B27 antigen. Furthermore, ankylosing spondylitis was found more frequently in ulcerative colitis bearing HLA-B27 compared with non-B27 patients (P less than 0-01). The same was found in Crohn's disease, although this difference was not statistically significant. In addition, 12 of 14 ulcerative colitis patients and five out of six Crohn's patients with HLA-B27 had total colitis, compared with the frequency of total colitis in non-B27 patients (P less than 0-024 and less than 0-03 respectively). The data suggest that B27 histocompatibility antigen could be a pathogenetic discriminator between the arthropathies in IBD and may be of prognostic significance with respect to extension and severity of the disease. (+info)

Expression of nitric oxide synthase in inflammatory bowel disease is not affected by corticosteroid treatment. (2/3046)

AIM: To examine the effect of corticosteroid treatment on the expression of inducible nitric oxide synthase (iNOS) in the colon of patients with inflammatory bowel disease. METHODS: Four groups of patients were studied: (1) ulcerative colitis treated with high dose corticosteroids (six patients, 10 blocks); (2) ulcerative colitis patients who had never received corticosteroids (10 patients, 16 blocks); (3) Crohn's disease treated with high dose corticosteroids (12 patients, 24 blocks); (4) Non-inflammatory, non-neoplastic controls (four patients, six blocks). Full thickness paraffin sections of colons removed at surgery were immunostained with an antibody raised against the C terminal end of iNOS. Sections were assessed semiquantitatively for the presence and degree of inflammation and immunoreactivity for nitric oxide synthase. RESULTS: Cases of ulcerative colitis and Crohn's disease with active inflammation showed strong staining for nitric oxide synthase. The staining was diffuse in ulcerative colitis and patchy in Crohn's disease, in accordance with the distribution of active inflammation. Staining was seen in epithelial cells and was most intense near areas of inflammation such as crypt abscesses. Non-inflamed epithelium showed no immunoreactivity. Treatment with corticosteroids made no difference to the amount of nitric oxide synthase. CONCLUSIONS: Expression of nitric oxide synthase is increased in both ulcerative colitis and Crohn's disease and appears to be unaffected by treatment with corticosteroids. Disease severity necessitated surgery in all the cases included in this study, regardless of whether or not the patients had received long term corticosteroid treatment. It seems therefore that a high level of iNOS expression and, presumably, production of nitric oxide characterise cases which are refractory to clinical treatment; this suggests that specific inhibition of the enzyme may be a useful therapeutic adjunct. (+info)

Perioperative growth hormone treatment and functional outcome after major abdominal surgery: a randomized, double-blind, controlled study. (3/3046)

OBJECTIVE: To evaluate short- and long-term effects of perioperative human growth hormone (hGH) treatment on physical performance and fatigue in younger patients undergoing a major abdominal operation in a normal postoperative regimen with oral nutrition. SUMMARY BACKGROUND DATA: Muscle wasting and functional impairment follow major abdominal surgery. METHODS: Twenty-four patients with ulcerative colitis undergoing ileoanal J-pouch surgery were randomized to hGH (12 IU/day) or placebo treatment from 2 days before to 7 days after surgery. Measurements were performed 2 days before and 10, 30, and 90 days after surgery. RESULTS: The total muscle strength of four limb muscle groups was reduced by 7.6% in the hGH group and by 17.1% in the placebo group at postoperative day 10 compared with baseline values. There was also a significant difference between treatment groups in total muscle strength at day 30, and at the 90-day follow-up total muscle strength was equal to baseline values in the hGH group, but still significantly 5.9% below in the placebo group. The work capacity decreased by approximately 20% at day 10 after surgery, with no significant difference between treatment groups. Both groups were equally fatigued at day 10 after surgery, but at day 30 and 90 the hGH patients were less fatigued than the placebo patients. During the treatment period, patients receiving hGH had reduced loss of limb lean tissue mass, and 3 months after surgery the hGH patients had regained more lean tissue mass than placebo patients. CONCLUSIONS: Perioperative hGH treatment of younger patients undergoing major abdominal surgery preserved limb lean tissue mass, increased postoperative muscular strength, and reduced long-term postoperative fatigue. (+info)

Biased JH usage in plasma cell immunoglobulin gene sequences from colonic mucosa in ulcerative colitis but not in Crohn's disease. (4/3046)

BACKGROUND: Ulcerative colitis is an inflammatory disease of the colonic and rectal mucosa. Autoantibodies have been observed in ulcerative colitis which may have a role in the pathogenesis of the disease. Evidence also suggests that there is an hereditary predisposition towards the disease, although no individual genes have been identified. AIMS: This is a pilot study of immunoglobulin heavy chain genes (IgH) in ulcerative colitis to determine whether they have any particular genetic characteristics which may lead to a better understanding of the disease aetiology. SUBJECTS: Colonic or rectal tissue was obtained from five children with ulcerative colitis. Tissue was also obtained from five children with Crohn's disease and five children who did not have inflammatory bowel disease as controls. METHODS: B cells and IgD+ B cells were identified by immunohistochemistry on frozen sections. Areas of lamina propria containing plasma cells, and areas of IgD+ B cells were microdissected. The immunoglobulin genes were PCR amplified, cloned, and sequenced. Sequences were analysed for content of somatic mutations and composition of heavy chain. RESULTS: An increase in the use of JH6 and DXP'1, and a decrease in the use of JH4, gene segments in immunoglobulin genes from lamina propria plasma cells, and from virgin IgD+ B cells, was found in patients with ulcerative colitis. These biases were not present in the control groups. CONCLUSIONS: There is a fundamental difference in the immunoglobulin genes from patients with ulcerative colitis. Whether this is caused by a difference in content of immunoglobulin gene segments in the germline or a difference in the recombination mechanism is not known. (+info)

Sulphation and secretion of the predominant secretory human colonic mucin MUC2 in ulcerative colitis. (5/3046)

BACKGROUND: Decreased synthesis of the predominant secretory human colonic mucin (MUC2) occurs during active ulcerative colitis. AIMS: To study possible alterations in mucin sulphation and mucin secretion, which could be the cause of decreased mucosal protection in ulcerative colitis. METHODS: Colonic biopsy specimens from patients with active ulcerative colitis, ulcerative colitis in remission, and controls were metabolically labelled with [35S]-amino acids or [35S]-sulphate, chase incubated and analysed by SDS-PAGE, followed by quantitation of mature [35S]-labelled MUC2. For quantitation of total MUC2, which includes non-radiolabelled and radiolabelled MUC2, dot blotting was performed, using a MUC2 monoclonal antibody. RESULTS: Between patient groups, no significant differences were found in [35S]-sulphate content of secreted MUC2 or in the secreted percentage of either [35S]-amino acid labelled MUC2 or total MUC2. During active ulcerative colitis, secretion of [35S]-sulphate labelled MUC2 was significantly increased twofold, whereas [35S]-sulphate incorporation into MUC2 was significantly reduced to half. CONCLUSIONS: During active ulcerative colitis, less MUC2 is secreted, because MUC2 synthesis is decreased while the secreted percentage of MUC2 is unaltered. Furthermore, sulphate content of secreted MUC2 is unaltered by a specific compensatory mechanism, because sulphated MUC2 is preferentially secreted while sulphate incorporation into MUC2 is reduced. (+info)

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. (6/3046)

Inflammatory bowel disease (IBD) is characterized by a chronic relapsing intestinal inflammation, typically starting in early adulthood. IBD is subdivided into two subtypes, on the basis of clinical and histologic features: Crohn disease and ulcerative colitis (UC). Previous genomewide searches identified regions harboring susceptibility loci on chromosomes 1, 3, 4, 7, 12, and 16. To expand our understanding of the genetic risk profile, we performed a 9-cM genomewide search for susceptibility loci in 268 families containing 353 affected sibling pairs. Previous linkages on chromosomes 12 and 16 were replicated, and the chromosome 4 linkage was extended in this sample. New suggestive evidence for autosomal linkages was observed on chromosomes 1, 6, 10, and 22, with LOD scores of 2.08, 2.07, 2.30, and 1.52, respectively. A maximum LOD score of 1.76 was observed on the X chromosome, for UC, which is consistent with the clinical association of IBD with Ullrich-Turner syndrome. The linkage finding on chromosome 6p is of interest, given the possible contribution of human leukocyte antigen and tumor necrosis-factor genes in IBD. This genomewide linkage scan, done with a large family cohort, has confirmed three previous IBD linkages and has provided evidence for five additional regions that may harbor IBD predisposition genes. (+info)

The systemic load and efficient delivery of active 5-aminosalicylic acid in patients with ulcerative colitis on treatment with olsalazine or mesalazine. (7/3046)

BACKGROUND: There have been reports of nephrotoxic reactions in patients with ulcerative colitis treated with 5-aminosalicylic acid (5-ASA) preparations. AIM: To compare the efficacy in delivery of active 5-ASA to the colon and the systemic load as the basis for potential long-term toxicity during treatment with olsalazine or mesalazine in patients with ulcerative colitis in remission. PATIENTS AND METHODS: Fifteen patients with ulcerative colitis were treated with olsalazine or mesalazine, each for 7 days in an open, randomized, crossover design study. 5-ASA and acetyl-5-ASA (Ac-5-ASA) in plasma and urine were measured by high performance liquid chromatography. RESULTS: The plasma concentration of 5-ASA was 1.2 +/- 0.1 micromol/L (mean +/- S.E.M.) for olsalazine and 8.0 +/- 1.9 micromol/L for mesalazine, while the plasma concentration of Ac-5-ASA was 2.8 +/- 0.2 micromol/L for olsalazine and 10.8 +/- 1.6 micromol/L for mesalazine. The amount of 5-ASA excreted in the urine was 68 +/- 30 micromol/24 h for olsalazine and 593 +/- 164 micromol/24 h for mesalazine. The amount of Ac-5-ASA in the urine was 1260 +/- 102 micromol/24 h for olsalazine and 3223 +/- 229 micromol/24 h for mesalazine. The urinary recovery of total 5-ASA plus Ac-5-ASA (as a percentage of the given dose) was 23 +/- 2.1% for olsalazine and 39 +/- 3.6% for mesalazine. The ratio between the plasma concentrations of mesalazine and olsalazine differed significantly both for 5-ASA (5.1) and Ac-5-ASA (3.6); for 5-ASA (9. 9) and Ac-5-ASA (2.6) in urine, and for the urinary recovery of total 5-ASA plus Ac-5-ASA (1.7). Moreover, in the mesalazine group there was a large variation in the individual plasma concentrations of 5-ASA and Ac-5-ASA, with maximal values 5-6-fold higher than that in the olsalazine group. CONCLUSION: The systemic load of active 5-ASA is significantly higher for mesalazine than for olsalazine, when based on the dosages given and when calculated on an equimolar basis. Some of the patients in the mesalazine group showed unexpected high levels of plasma and urinary 5-ASA concentrations, a finding which may have long-term safety implications. (+info)

Is maintenance therapy always necessary for patients with ulcerative colitis in remission? (8/3046)

BACKGROUND: The efficacy of sulphasalazine and mesalazine in preventing relapse in patients with ulcerative colitis is well known. It is less clear how long such maintenance should be continued, and if the duration of disease remission is a factor that affects the risk of recurrence. AIM: To determine whether the duration of disease remission affects the relapse rate, by comparing the efficacy of a delayed-release mesalazine (Asacol, Bracco S.p.A., Milan, Italy) against placebo in patients with ulcerative colitis with short- and long-duration of disease remission. METHODS: 112 patients (66 male, 46 female, mean age 35 years), with intermittent chronic ulcerative colitis in clinical, endoscopic and histological remission with sulphasalazine or mesalazine for at least 1 year, were included in the study. Assuming that a lower duration of remission might be associated with a higher relapse rate, the patients were stratified according to the length of their disease remission, prior to randomization into Group A (Asacol 26, placebo 35) in remission from 1 to 2 years, or Group B (Asacol 28, placebo 23) in remission for over 2 years, median 4 years. Patients were treated daily with oral Asacol 1.2 g vs. placebo, for a follow-up period of 1 year. RESULTS: We employed an intention-to-treat analysis. In Group A, whilst no difference was found between the two treatments after 6 months, mesalazine was significantly more effective than placebo in preventing relapse at 12 months [Asacol 6/26 (23%), placebo 17/35 (49%), P = 0.035, 95% Cl: 48-2.3%]. In contrast, in Group B no statistically significant difference was observed between the two treatments, either at 6 or 12 months [Asacol 5/28 (18%), placebo 6/23 (26%), P = 0.35, 95% Cl: 31-14%] of follow-up. Patients in group B were older, and had the disease and remission duration for longer, than those in Group A. CONCLUSIONS: Mesalazine prophylaxis is necessary for the prevention of relapse by patients with ulcerative colitis in remission for less than 2 years, but this study casts doubt over whether continuous maintenance treatment is necessary in patients with prolonged clinical, endoscopic and histological remission, who are at very low risk of relapse. (+info)

... ". JAMA. 307 (1): 104. doi:10.1001/jama.2011.1889. PMID 22215172. MedlinePlus ulcerative colitis page (CS1 ... "Ulcerative Colitis". NIDDK. September 2014. Retrieved 3 August 2016. "Ulcerative Colitis". Autoimmune Registry Inc. Retrieved ... The first description of ulcerative colitis occurred around the 1850s. People with ulcerative colitis usually present with ... ulcerative colitis is usually confined to the colon. Inflammation in ulcerative colitis is usually continuous, typically ...

https://en.wikipedia.org/wiki/Ulcerative_colitis

... by the type of ulcerative colitis: Aminosalicylates are the main anti-inflammatory drugs used to treat ulcerative colitis. ... Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes ... Ulcerative colitis is a disease that affects many parts of the body outside the intestinal tract. In rare cases the extra- ... Ulcerative colitis is, however, a systemic disease that affects many parts of the body outside the intestine. Standard ...

https://en.wikipedia.org/wiki/Management_of_ulcerative_colitis

"Ulcerative Colitis by Hank Green". Youtube. "8 Famous People With Ulcerative Colitis". Health.com. "How I Escaped My Certain ... "How Ulcerative Colitis Affects a Family". everydayhealth. Retrieved 13 October 2012. "For King & Country gives thanks for ... about.com "8 Famous People With Ulcerative Colitis". Health.com. "Der Spiegel, "Sie müssen Geduld haben" ('You need to be ... The following is a list of notable people diagnosed with ulcerative colitis. Pollock, John (1977), Wilberforce, New York: St. ...

https://en.wikipedia.org/wiki/List_of_people_diagnosed_with_ulcerative_colitis

Ulcerative Colitis. Updates in Surgery. 2019. doi:10.1007/978-88-470-3977-3. ISBN 978-88-470-3976-6. S2CID 1135267.[page needed ... With the advancement of ileal-anal pouch surgery, selected patients with ulcerative colitis (UC) and familial adenomatous ... A Single Cohort Experience of 409 Patients With Chronic Ulcerative Colitis". Annals of Surgery. 240 (4): 615-623. doi:10.1097/ ... "Proctocolectomy without ileostomy for ulcerative colitis". BMJ. 2 (6130): 85-88. doi:10.1136/bmj.2.6130.85. PMC 1605901. PMID ...

https://en.wikipedia.org/wiki/John_Nicholls_(professor)

"Ulcerative Colitis". The Lecturio Medical Concept Library. 26 August 2020. Retrieved 22 August 2021. "Henoch-Schönlein Purpura ... including Crohn's disease and ulcerative colitis) Henoch-Schönlein purpura Hyperimmunoglobulinemia D with recurrent fever ...

https://en.wikipedia.org/wiki/Arthritis

"Ulcerative Colitis Symptoms, Diet, Treatment & Medication". Retrieved 2016-06-27. "Ulcerative colitis". 2016-03-17. Retrieved ... Pancolitis or universal colitis is frequently used in a more specific fashion to denote a very severe form of ulcerative ... This form of ulcerative colitis is spread throughout the entire large intestine including the right colon, the left colon, the ... Patients with ulcerative colitis generally exhibit symptoms including rectal bleeding as a result of ulcers, pain in the ...

https://en.wikipedia.org/wiki/Pancolitis

"Ulcerative Colitis". NIDDK. September 2014. Archived from the original on 28 July 2016. Retrieved 3 August 2016. v t e (Drugs ... An aminosalicylate is a class of medications that is often used to treat ulcerative colitis and Crohn's disease. The class ...

https://en.wikipedia.org/wiki/Aminosalicylate

"Ulcerative Colitis". PubMed Health. October 16, 2011. "Rock of Love 2: Meet Lyanna". BuddyTV. January 7, 2008. Archived from ... At 10 years old, Martin was diagnosed with ulcerative colitis. It is an inflammatory bowel disease that affects the lining of ... List of people diagnosed with ulcerative colitis "'The Voice's' Erin Martin is More Than Just A Model Turned Singer: Interview ...

https://en.wikipedia.org/wiki/Erin_Martin

Ulcerative colitis an ulcerative form of colitis, is the other major inflammatory bowel disease which is restricted to the ... Ulcerative colitis is the most common of the IBDs Irritable bowel syndrome (IBS) is the most common of the functional ... Medicine portal Ulcerative colitis Abdominal internal oblique muscle Kong F, Singh RP (June 2008). "Disintegration of solid ... Danese S, Fiocchi C (November 2011). "Ulcerative colitis". The New England Journal of Medicine. 365 (18): 1713-1725. doi: ...

https://en.wikipedia.org/wiki/Human_digestive_system

... or in the colon if a person has ulcerative colitis. Crohn's disease Ulcerative colitis Enteritis-inflammation of the small ... "Ulcerative Colitis". NIDDK. September 2014. Retrieved Dec 6, 2017. "Crohn's disease: Symptoms". MayoClinic.com. 2011-08-09. ... Inflammatory bowel disease is also divided into separate conditions, namely ulcerative colitis and Crohn's disease, which have ... Colitis can be divided into infectious and drug induced, as can the treatment for these conditions. With infectious colitis, ...

https://en.wikipedia.org/wiki/Blood_in_stool

Ulcerative colitis mainly affects the function of the large bowel, and its incidence rate is three times larger than the ... Crohn's disease (CD) and ulcerative colitis (UC) are the two universal type of inflammatory bowel diseases that have been ... Steed, Helen (May 2019). "Ulcerative colitis". Medicine. 47 (6): 371-376. doi:10.1016/j.mpmed.2019.03.001. S2CID 243328622. ...

https://en.wikipedia.org/wiki/Defecation

"Localised giant pseudopolyposis secondary to ulcerative or granulomatous colitis". Clinical Radiology. 28 (6): 609-16. doi: ... Ulcerative Colitis: Pseudopolyps; http://www.endoatlas.com/ib_uc_03.html Joffe, N (November 1977). " ...

https://en.wikipedia.org/wiki/Pseudopolyps

Indeterminate colitis is the classification for colitis that has features of both Crohn's disease and ulcerative colitis. ... Lymphocytic colitis Collagenous colitis Diversion colitis Chemical colitis Chemotherapy-induced colitis Radiation colitis ... Indeterminate colitis' behaviour is usually closer to ulcerative colitis than Crohn's disease. Atypical colitis is a phrase ... "Ulcerative colitis - Symptoms - NHS Choices". www.nhs.uk. Retrieved 2015-11-03. "Diagnosis of Ulcerative Colitis , NIDDK". ...

https://en.wikipedia.org/wiki/Colitis

Hardy, T. L.; Bulmer, Ernest (4 November 1933). "Ulcerative colitis: a survey of ninety-five cases". Br Med J. 2 (3800): 812- ... Hardy, T. L.; Brooke, B. N.; Hawkins, C. F. (1949). "Ileostomy and ulcerative colitis". The Lancet. 254 (6566): 4-6. doi: ... This revolutionised the therapy for ulcerative colitis. In 1914 T. Lionel Hardy married Elizabeth Clarke Ritchie. They had ...

https://en.wikipedia.org/wiki/Thomas_Lionel_Hardy

In February 2014, he said that he had ulcerative colitis. In July 2016, Wilkins was given a four-year ban for drink driving. In ... "Ray Wilkins has Ulcerative Colitis". The Daily Telegraph. London. 19 February 2014. Archived from the original on 12 January ...

https://en.wikipedia.org/wiki/Ray_Wilkins

The gut microbiome is altered from antibiotics and is linked to future gut disease, i.e., IBD, ulcerative colitis, obesity, etc ... Severe or chronic infections of C. difficile can lead to inflammation of the colon, a condition known as colitis. Periodontitis ... Surawicz CM, McFarland LV, Elmer G, Chinn J (October 1989). "Treatment of recurrent Clostridium difficile colitis with ... and colitis. There is no single or well understood microbial cause of IBD, but three major pathogens have been associated with ...

https://en.wikipedia.org/wiki/Dysbiosis

"Granulomatous ulcerative colitis: a re-appraisal of the mucosal granuloma in the distinction of Crohn's disease from ulcerative ... Visible bleeding in the feces is less common in Crohn's disease than in ulcerative colitis, but is not unusual. Bloody bowel ... Although the association is greater in the context of ulcerative colitis, Crohn's disease may also be associated with primary ... Tysk C, Lindberg E, Järnerot G, Flodérus-Myrhed B (July 1988). "Ulcerative colitis and Crohn's disease in an unselected ...

https://en.wikipedia.org/wiki/Crohn's_disease

Fluegelman suffered from ulcerative colitis. In July 1985, he was prescribed prednisone to treat the condition. Within a few ...

https://en.wikipedia.org/wiki/Andrew_Fluegelman

Crohn's disease or ulcerative colitis; diverticulitis; severe hepatic impairment. Concomitant use of fluvoxamine is also ... The FDA said it had reports of 49 cases of ischemic colitis and 21 cases of "severe constipation" and that ten of the 70 ... Severe adverse events continued to be reported, with a final total of 84 instances of ischaemic colitis, 113 of severe ... The cumulative incidence of ischaemic colitis was 2 in 1000, while serious complications arising from constipation (obstruction ...

https://en.wikipedia.org/wiki/Alosetron

See Trendelenburg position.) Brooke BN (1961). "Malignant change in ulcerative colitis". Diseases of the Colon & Rectum. 4 (6 ... was a British surgeon and pioneer of surgery for ulcerative colitis. The son of numismatist George C. Brooke, after education ... Eade MN; Cooke WT; Brooke BN; Thompson, H. (1971). "Liver disease in Crohn's colitis: a study of 21 consecutive patients having ...

https://en.wikipedia.org/wiki/Bryan_Nicholson_Brooke

Hurst, Arthur F. (1931). "A paper on ulcerative colitis". British Medical Journal. 1 (3668): 693-694. doi:10.1136/bmj.1.3668. ... Among his major discoveries, Wilks recognised ulcerative colitis in 1859, differentiating it from bacterial dysentery. His work ... autopsy of a 42-year-old woman who died after several months of diarrhoea and fever demonstrated a transmural ulcerative ...

https://en.wikipedia.org/wiki/Samuel_Wilks

Ulcerative colitis, in contrast, is restricted to the colon and the rectum. Microscopically, ulcerative colitis is restricted ... Conditions with similar symptoms as ulcerative colitis includes acute self-limiting colitis, amebic colitis, schistosomiasis, ... Microscopic colitis subdivided into collagenous colitis and lymphocytic colitis Diversion colitis Behçet's disease Early Onset ... "Granulomatous ulcerative colitis: a re-appraisal of the mucosal granuloma in the distinction of Crohn's disease from ulcerative ...

https://en.wikipedia.org/wiki/Inflammatory_bowel_disease

Deepak, P; Bruining, DH (Aug 2014). "Radiographical evaluation of ulcerative colitis". Gastroenterology Report. 2 (3): 169-77. ... In pseudomembranous colitis, barium studies show pancolitis with thumb printing and shaggy margins as well as plaque-like ... Schistosomiasis caused by infection with flatworms have an appearance resembling colitis ulcerosa, with inflammatory polyps, ...

https://en.wikipedia.org/wiki/Upper_gastrointestinal_series

He introduced a popular modification to the technique for creating an ileo-anal pouch , or j-pouch for ulcerative colitis, in ... Bach, Simon P; Mortensen, Neil J (28 June 2007). "Ileal pouch surgery for ulcerative colitis". World Journal of ...

https://en.wikipedia.org/wiki/Steven_D._Wexner

T.R. Sullivan (August 8, 2020). "Palumbo (ulcerative colitis) goes to IL". MLB.com. Retrieved December 1, 2020. Kennedi Landry ... before missing the rest of the season after being diagnosed with ulcerative colitis. Palumbo played the 2021 season with the ...

https://en.wikipedia.org/wiki/Joe_Palumbo_(baseball)

Ulcerative colitis involves the colonic mucosa. Crohn's disease may produce inflammation in all layers in any part of the ... This is called esophagitis, gastritis, duodenitis, ileitis, and colitis depending on the parts affected. It can be due to ...

https://en.wikipedia.org/wiki/Gastrointestinal_wall

Picardo S, Panaccione R (April 2020). "Anti-MADCAM therapy for ulcerative colitis". Expert Opinion on Biological Therapy. 20 (4 ... 2002). "Differential expression of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in ulcerative colitis and Crohn's ... 2002). "Differential expression of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in ulcerative colitis and Crohn's ...

https://en.wikipedia.org/wiki/Addressin

Dragstedt, L. R.; Dack, G. M.; Kirsner, J. B. (1941). "Chronic Ulcerative Colitis: A Summary of Evidence Implicating Bacterium ... In addition to his research on staphylococcal food poisoning, Dack studied botulism, ulcerative colitis, and salmonella ... Dack, G. M. (1936). "Bacterium Necrophorum in Chronic Ulcerative Colitis". Journal of the American Medical Association. 106: 7 ... "Effect of introducing oxygen into the isolated colon of a patient with chronic ulcerative colitis". American Journal of ...

https://en.wikipedia.org/wiki/Gail_Monroe_Dack

Truelove, S. C.; Witts, L. J. (14 February 1959). "Cortisone and Corticotrophin in Ulcerative Colitis". Br Med J. 1 (5119): 387 ...

https://en.wikipedia.org/wiki/Leslie_John_Witts

Parks, A. G.; Nicholls, R. J. (1978). "Proctocolectomy without ileostomy for ulcerative colitis". BMJ. 2 (6130): 85-88. doi: ...

https://en.wikipedia.org/wiki/Alan_Parks

He began writing the book in high school after he lost his playing career to ulcerative colitis. The book was publicly praised ... Carver has struggled with health complications, and has been hospitalized frequently with ulcerative colitis, which caused him ...

https://en.wikipedia.org/wiki/Johnny_Carver_(sports_author)

... particularly Crohn's Disease and Ulcerative Colitis and regressive behavioural disease (RBD) (also referred to as "Pervasive ... The Editors of The Lancet (February 2010). "Retraction - Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and ... "non-specific colitis"; The parents of eight children were reported as blaming MMR, but 11 families made this allegation at the ... chronic colitis and pervasive developmental disorder including autism (RBD), in some infants. According to Deer, a letter from ...

https://en.wikipedia.org/wiki/Andrew_Wakefield

... induction of peripheral lymph node addressin on high endothelial venule-like vessels in the active phase of ulcerative colitis ...

https://en.wikipedia.org/wiki/CD34

... as treatment for ulcerative colitis, a preventive measure in certain genetic illnesses such as FAP or HNPCC or as a procedure ...

https://en.wikipedia.org/wiki/Pouchoscopy

Other conditions, such as anal cancer may be associated with ulcerative colitis or with sexually transmitted infections such as ... Inflammatory bowel disease is a condition of unknown aetiology, classified as either Crohn's disease or ulcerative colitis, ... Generalised inflammation of the large intestine is referred to as colitis, which when caused by the bacteria Clostridium ... difficile is referred to as pseudomembranous colitis. Diverticulitis is a common cause of abdominal pain resulting from ...

https://en.wikipedia.org/wiki/Gastrointestinal_disease

... colectomy and ileoanal anastomosis to remove his large intestines after years of suffering from severe ulcerative colitis. UCLA ... CrispinBasketball.com Jon Crispin's Coca-Cola commercial (Webarchive template wayback links, Articles with short description, ... and Coca-Cola, as well as modeled for print advertisements. When he resided in Los Angeles, California, Jon began his ...

https://en.wikipedia.org/wiki/Jon_Crispin

January 2014). "The *1244 A>G polymorphism of MyD88 (rs7744) is closely associated with susceptibility to ulcerative colitis". ... them an association with susceptibility to various infectious diseases and to some autoimmune diseases like ulcerative colitis ...

https://en.wikipedia.org/wiki/MYD88

... formulation of live bacteria may be used in combination with conventional therapies to treat ulcerative colitis, and requires a ...

https://en.wikipedia.org/wiki/Bifidobacterium_longum

... ulcerative colitis, regional enteritis, cholecystitis, renal colic, perforated peptic ulcer, pancreatitis, rectus sheath ... new-onset Crohn's disease or ulcerative colitis, pancreatitis, and abdominal trauma from child abuse; distal intestinal ...

https://en.wikipedia.org/wiki/Appendicitis

... ulcerative colitis, lupus, sympathetic ophthalmia, temporal arteritis, uveitis, ocular inflammation, keloids, urushiol-induced ...

https://en.wikipedia.org/wiki/Triamcinolone

Butyrate also possesses anti-inflammatory effects to decrease colonic inflammation such as ulcerative colitis. One study ...

https://en.wikipedia.org/wiki/Butyrate_kinase

... and may occur in ulcerative colitis with rebound tenderness in the right lower quadrant. However, in recent years[when?] the ...

https://en.wikipedia.org/wiki/Blumberg_sign

February 2009). "Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study". Nature ... December 2009). "A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the ...

https://en.wikipedia.org/wiki/Dihydrolipoamide_dehydrogenase

Colitis Activity Index is a tool used in clinical research to measure quantify the impact of symptoms of ulcerative colitis. ...

https://en.wikipedia.org/wiki/Lichtiger_colitis_activity_index

Abrams suffers from ulcerative colitis, an inflammatory disease which causes ulceration and inflammation of the colon, and that ... List of people diagnosed with ulcerative colitis "Casey Abrams, Idol's Jazz Man". My Fox Memphis. March 8, 2011. Archived from ...

https://en.wikipedia.org/wiki/Casey_Abrams

Rare causes of skin ulcers include pyoderma gangraenosum, lesions caused by Crohn's disease or ulcerative colitis, ...

https://en.wikipedia.org/wiki/Ulcer_(dermatology)

Another case published in 2013 reported on a patient who developed ulcerative colitis due to Hydroxycut Hardcore. In October ... "Ulcerative colitis associated with the herbal weight loss supplement Hydroxycut". BMJ Case Rep. 2013: bcr2012007509. doi: ...

https://en.wikipedia.org/wiki/Hydroxycut

This included "a higher one for certain specific conditions such as diabetes and ulcerative colitis and a lower one where a ...

https://en.wikipedia.org/wiki/Labour_government,_1964–1970

Patients with inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, have significantly more ... PGLYRP3-deficient mice are more sensitive than wild type mice to dextran sodium sulfate (DSS)-induced colitis, which indicates ... The anti-inflammatory effect of PGLYRP3 on DSS-induced colitis depends on the PGLYRP3-regulated intestinal microbiome, because ... which affect their sensitivity to colitis. Mouse PGLYRP3 plays a role in maintaining anti- and pro-inflammatory homeostasis in ...

https://en.wikipedia.org/wiki/Peptidoglycan_recognition_protein_3

It is often used as treatment for infantile spasms, multiple sclerosis, nephrotic syndrome, gout, ulcerative colitis, Crohn's ...

https://en.wikipedia.org/wiki/ACTH_receptor

Original guitarist Alves died on March 12, 2017, at the age of 63 from ulcerative colitis and inflammatory bowel disease. Alves ...

https://en.wikipedia.org/wiki/Y&T

... and ulcerative colitis. 59 percent of patients with relapsing polychondritis have either episcleritis or scleritis. Rarely, ...

https://en.wikipedia.org/wiki/Episcleritis

Steenland K, Zhao L, Winquist A, Parks C (August 2013). "Ulcerative colitis and perfluorooctanoic acid (PFOA) in a highly ... ulcerative colitis, thyroid disease, pregnancy-induced hypertension and high cholesterol. In October 2018, a class action suit ... ulcerative colitis, thyroid disease, testicular cancer, kidney cancer as well as pregnancy-induced hypertension and ...

https://en.wikipedia.org/wiki/Per-_and_polyfluoroalkyl_substances

Crohn's disease and ulcerative colitis). The above applies to humans. In other organisms, the function of dendritic cells can ...

https://en.wikipedia.org/wiki/Dendritic_cell

... ulcerative colitis, bacterial colitis (e.g. syphilitic colitis), anal/perianal tuberculosis, perianal abscess (when ruptured). ... Rectal bleeding Colitis Proctitis Adam S Cheifetz; Alphonso Brown; Michael Curry; Alan C Moss (10 Mar 2011). Oxford American ... When the fecal stream is diverted as part of a colostomy, a condition called diversion colitis may develop in the section of ... Long-term lack of exposure to these nutrients can cause inflammation of the colon (colitis). Symptoms include rectal bleeding, ...

https://en.wikipedia.org/wiki/Rectal_discharge

In 2013, Douglas and Reader were married, shortly after which he was diagnosed with the autoimmune disease, ulcerative colitis ...

https://en.wikipedia.org/wiki/The_Trash_Can_Sinatras

Rates of gastrointestinal cancers are increased in people with Crohn's disease and ulcerative colitis, due to chronic ... Cole BF, Baron JA, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, et al. (June 2007). "Folic acid for the prevention of ...

https://en.wikipedia.org/wiki/Cancer

Ulcerative colitis is a chronic disorder that affects the digestive system . Explore symptoms, inheritance, genetics of this ... medlineplus.gov/genetics/condition/ulcerative-colitis/ Ulcerative colitis. ... which may cause the chronic inflammation that occurs in ulcerative colitis. Another possible explanation is that ulcerative ... Ulcerative colitis is one common form of inflammatory bowel disease. (IBD). Another type of IBD, Crohn disease, also causes ...

https://medlineplus.gov/genetics/condition/ulcerative-colitis

A 45-year-old woman with ulcerative colitis is having difficulty with her medication and would like to try probiotics. How ... Pregnancy, Fertility, Ulcerative Colitis: Facts vs Fiction * Ulcerative Colitis Cases Projected to Top 2 Million in Eight ... Optimizing Patient Management in Ulcerative Colitis: The Urgent Patient Need 0.25 CME / ABIM MOC Credits ... Ulcerative Colitis Cases Projected to Top 2 Million in Eight Countries by 2031 ...

https://www.medscape.com/viewarticle/874513

Ulcerative colitis (UC) is one of the 2 major types of inflammatory bowel disease (IBD), along with Crohn disease. Unlike Crohn ... Ulcerative Colitis. Plain abdominal radiograph in a 26-year-old with a 10-year history of ulcerative colitis shows a long ... Ulcerative Colitis. Single-contrast enema study in a patient with known ulcerative colitis in remission shows a benign ... Ulcerative Colitis. Plain abdominal radiograph from a patient with known ulcerative colitis who presented with an acute ...

https://emedicine.medscape.com/article/183084

Ulcerative colitis. Definition. Ulcerative colitis is an inflammatory bowel disease that is characterized by chronic ... In vivo self-assembled siRNA as a modality for combination therapy of ulcerative colitis Management of ulcerative colitis can ... Keeping ulcerative colitis in check Upadacitinib, a JAK inhibitor, may help patients with moderate to severely active ... Prevalence of cerebrovascular accidents in patients with ulcerative colitis in a single academic health system *Erika Horta ...

https://www.nature.com/subjects/ulcerative-colitis?error=cookies_not_supported&code=50453d53-b575-40e8-9d09-a1fec5a4a0e4

Ulcerative colitis (UC) is an inflammatory condition that can cause constipation and other symptoms. Here, learn some tips on ... Learn more about ulcerative colitis remission here. Q:. Is it safe to eat high fiber foods with ulcerative colitis, or might ... In distal ulcerative colitis, the symptoms only affect the left side of the colon. When a person has ulcerative colitis on the ... In some people, ulcerative colitis causes constipation.. Common symptoms of ulcerative colitis include diarrhea and bloody, ...

https://www.medicalnewstoday.com/articles/320256

Chronic ulcerative colitis is being encountered with increasing frequency in developing countries. In Amman, Jordan, the ... Review of chronic ulcerative colitis cases at King Hussein Medical Centre, Jordan ... records of 372 patients with chronic ulcerative colitis diagnosed between 1994 and 2001 were reviewed. ... ...

https://extranet.who.int/iris/restricted/browse?authority=Colitis%2C+Ulcerative&type=mesh

Ulcerative colitis (UC) symptoms like diarrhea, pain, and fatigue can require you to make some adjustments to your sex life. ... Ulcerative Colitis Answers and Community Stories. Ulcerative colitis questions answered and stories from the ulcerative colitis ... Living with ulcerative colitis often feels like youre in the middle of a bad movie. These movie titles sum up what life with ... Ulcerative colitis (UC) symptoms like diarrhea, pain, and fatigue can require you to make some adjustments to your sex life. ...

https://www.healthline.com/health/ulcerative-colitis/9-ways-ulcerative-colitis-can-affect-your-sex-life-and-how-to-manage

Ulcerative colitis is an inflammatory bowel disease of the large intestines. Inflammation usually occurs in the rectum and ... Ulcerative Colitis Ulcerative colitis, often simply called colitis, is a chronic inflammatory disease of the large intestine ( ... Ulcerative colitis is a type of inflammatory bowel disease (IBD).. Most people with colitis are diagnosed before the age of 30 ... Our Approach to Ulcerative Colitis. UCSF provides comprehensive evaluations and advanced care for all types of IBD, including ...

https://www.ucsfhealth.org/conditions/ulcerative-colitis

Reviews and ratings for Colazal when used in the treatment of ulcerative colitis. 6 reviews submitted with a 6.2 average score. ... Ulcerative Colitis Treatment Options, Compared * Learn about a popular treatment for Ulcerative Colitis ... User Reviews for Colazal to treat Ulcerative Colitis. Colazal has an average rating of 6.2 out of 10 from a total of 6 ratings ... treatment of Ulcerative Colitis. 50% of reviewers reported a positive experience, while 33% reported a negative experience. ...

https://www.drugs.com/comments/balsalazide/colazal-for-ulcerative-colitis.html

The aim of this study was to determine the long-term outcome among 390 patients with ulcerative colitis who underwent ileal J ... Ileal pouch-anal anastomosis for chronic ulcerative colitis. Long-term results Ann Surg. 1987 Oct;206(4):504-13. doi: 10.1097/ ... The aim of this study was to determine the long-term outcome among 390 patients with ulcerative colitis who underwent ileal J ... pouch-anal anastomosis achieved a reasonable stool frequency and satisfactory continence in patients with ulcerative colitis ...

https://pubmed.ncbi.nlm.nih.gov/3662660/?dopt=Abstract

... is a chronic inflammatory bowel disease affecting the lining of the colon. ... Ulcerative colitis. Ulcerative colitis is a chronic inflammatory bowel disease affecting the lining of the colon. ... Pregnancy and ulcerative colitis *Disease does not present a hurdle. *Attacks or relapses are typical, in particular in the ... Ulcerative colitis is a chronic inflammatory bowel disease affecting the lining of the colon. The cause is unknown. The disease ...

https://www.css.ch/en/private-customers/my-health/health-glossary/conditions/ulcerative-colitis.html

Ginger Improves Symptoms of Ulcerative Colitis, Enhances Quality of Life Bowel and digestive problems like ulcerative colitis ... Ulcerative colitis is associated with dysbios and can be reversed in some patients through colonic infusion of healthy human ... 18 Abstracts with Colitis: Ulcerative Research. Filter by Study Type. Animal Study. ... Fish oil fatty acid supplementation improves mild to moderate ulcerative colitis and reduces or eliminates the need for anti- ...

https://greenmedinfo.com/disease/colitis-ulcerative

Find Crohns disease and ulcerative colitis information, including symptoms, prevention, and promising treatments. ... May 5, 2010 - People with inflammatory bowel disease -- especially men and people with ulcerative colitis -- may be at ... Crohns, Colitis May Be Tied to Prostate Cancer December 14, 2018 - In a recent study, men with inflammatory bowel disease had ... Crohns, Colitis May Be Tied to Heart Risk October 14, 2013 - Review of previous studies finds link between inflammatory bowel ...

https://www.webmd.com/ibd-crohns-disease/news/default.htm

Etrasimod Shows Promise in Moderate to Severe Ulcerative Colitis. - Analysis of two ELEVATE trials showed significant ... "Etrasimod 2mg once daily as treatment for moderately to severely active ulcerative colitis: results from the phase 3 ELEVATE UC ... led to clinically meaningful improvements in patients with moderately to severely active ulcerative colitis (UC), according to ...

https://www.medpagetoday.com/meetingcoverage/ddw/98918

Megacolon Complicating Ulcerative Colitis and Clostridiodes Infection. Download Prime PubMed App to iPhone, iPad, or Android ... Surgical intervention in chronic ulcerative colitis and granulomatous colitis.. *[Emergencies and urgent operations in ... "Megacolon Complicating Ulcerative Colitis and Clostridiodes Infection." The American Journal of the Medical Sciences, vol. 360 ... Bacterial ToxinsClostridioides difficileClostridium InfectionsColectomyColitis, UlcerativeFecesHumansMaleMegacolon, Toxic ...

https://www.unboundmedicine.com/medline/citation/32448498/Megacolon_Complicating_Ulcerative_Colitis_and_Clostridiodes_Infection_

... By RTTNews Staff Writer ✉ , Published: 1/21/2021 9: ... Immutep noted that GSK2831781 has also been explored in another autoimmune disease beyond ulcerative colitis. It was previously ... in patients with active ulcerative colitis.. GlaxoSmithKline stopped the trial based on the assessment of clinical data as part ...

https://www.rttnews.com/3162407/immutep-glaxosmithkline-discontinues-phase-ii-study-on-ulcerative-colitis.aspx

Colitis. Colitis, Ulcerative. Ulcer. Gastroenteritis. Gastrointestinal Diseases. Digestive System Diseases. Colonic Diseases. ... Intravenous corticosteroids in moderately active ulcerative colitis refractory to oral corticosteroids. J Crohns Colitis. 2014 ... Endovenous Corticosteroid Pulses in Moderate Ulcerative Colitis (CECUM). The safety and scientific validity of this study is ... MedlinePlus related topics: Steroids Ulcerative Colitis Drug Information available for: Prednisolone Prednisolone acetate ...

https://clinicaltrials.gov/ct2/show/NCT02921555

US-2016175270-A1 chemical patent summary.

https://pubchem.ncbi.nlm.nih.gov/patent/US-2016175270-A1

Effective natural remedies to treat Ulcerative Colitis include dietary changes, pH balancing tonics like Apple Cider Vinegar, ... I have ulcerative colitis (UC) and have to take mesalamines everyday to keep it under control. I agree with Ted from Bangkok ... I was diagnosed with Ulcerative Colitis via biopsy during colonoscopy. I am allergic to the drug used to treat UC and was ...

https://www.earthclinic.com/cures/ulcerative-colitis-holistic-treatment.html?toc=Multiple+Remedies&ratingvalue=4&sortby=latest

Clinical trial for Ulcerative Colitis , Ulcerative Colitis (UC) Study at ClinSearch ... Ulcerative Colitis (UC) is another form of inflammatory bowel disease (IBS). Unlike Crohns, which can affect any part of the ...

https://www.centerwatch.com/clinical-trials/listings/228697/ulcerative-colitis-uc-study-at-clinsearch-2/

What happens when ulcerative colitis patients consume alcohol on a regular basis?. 1. Alcohol leads to flare-ups that aggravate ... or specialised surgical procedures that help curb the aggravation of ulcerative colitis signs and GI inflammation. ... which leads to experiencing significant improvements in ulcerative colitis signs and gastrointestinal inflammation symptoms. ... and more complex for people who have other conditions that concern the digestive apparatus such as when ulcerative colitis ...

https://www.healthynewage.com/does-alcohol-cause-and-worsen-ulcerative-colitis/

Remicades challenging dosing reduces its impact as an ideal ulcerative colitis drug. Despite its strong efficacy, Remicade is ... reports/ulcerative-. colitis-rat..., supports strategy development for both existing and developing ulcerative colitis brands. ... New Research Finds Awareness Low for Ulcerative Colitis Pipeline Drugs. New Ulcerative Colitis Drugs Provide Excitement to ... perceptions of ulcerative colitis brands clinical benefits. The data identify which ulcerative colitis brands HCPs perceive as ...

https://www.prlog.org/12934770-remicades-challenging-dosing-reduces-its-impact-as-an-ideal-ulcerative-colitis-drug.html

Mayo Clinic researchers report that cases of Crohns disease and ulcerative colitis - [...] ...

https://discoverysedge.mayo.edu/blogtag/ulcerative-colitis/

Our ulcerative colitis treatment helps patients achieve remission, avoid flare-ups and have the best quality of life. Services ... What is Ulcerative Colitis? Ulcerative colitis is a type of inflammatory bowel disease that affects the large intestine (the ... When we treat ulcerative colitis, we often start with medicines that work on the lining of the bowel in an effective way. But ... Ulcerative colitis causes a type of inflammation thats a bit more superficial and confined to the mucosa, or the lining of the ...

https://www.uchicagomedicine.org/conditions-services/inflammatory-bowel-disease/ulcerative-colitis

Long-Term Study Of CP-690,550 In Subjects With Ulcerative Colitis (OCTAVE) A Multi-Center, Open-Label Study of CP-690,550 in ...

https://www.pfizer.com/science/clinical-trials/plain-language-study-results-summaries/long-term-study-cp-690550-subjects

... Share ... WDSU sports anchor Fletcher Mackel said Mauti told reporters that he will have surgery for ulcerative colitis, a chronic ... WDSU sports anchor Fletcher Mackel said Mauti told reporters that he will have surgery for ulcerative colitis, a chronic ... New Orleans Saints linebacker Michael Mauti revealed Tuesday hes undergoing surgery for ulcerative colitis and will be out the ...

https://www.wdsu.com/article/saints-linebacker-michael-mauti-out-for-season-to-undergo-treatment-for-ulcerative-colitis/8293740

Ulcerative colitis and Crohn disease are the two main forms of inflammatory bowel disease. ... crohns disease vs ulcerative colitis - Google Search. *Ulcerative Colitis vs Crohns Disease - UCLA Center for Inflammatory ... Clinical Pearl of the Day: Crohn Disease vs Ulcerative Colitis. In Crohn disease (CD), there are some parts of the intestine ... Ulcerative colitis and Crohn disease are the two main forms of inflammatory bowel disease. ...

https://www.pharmacytimes.com/view/clinical-pearl-of-the-day-crohn-disease-vs-ulcerative-colitis

Treating for ulcerative colitis can be difficult. What options do we need to know about? ... Sara Horst about ulcerative colitis therapy.. So, Dr. Horst, turning to ozanimod, where does this fit in the treatment of ... I think one of the big takeaways for me when I think about a patient who has ulcerative colitis, and I kind of alluded to this ... This is an oral medicine that can be used for moderate to severe ulcerative colitis first-line. When I look at the phased ...

https://reachmd.com/programs/gi-insights/key-considerations-for-treating-ulcerative-colitis/14221/

Colitis, IBS help with prebiotics, probiotics Perfect Pass, Visbiome, VSL#3, Dr Ohhira, Primal Defense and Genova & Doctors ...

https://www.crohns.net/health-concern/colitis-ulcerative-colitis.html?manufacturer=44

In a comprehensive piece published on Nola.com Saturday, Mauti revealed he was diagnosed with ulcerative colitis prior to his ... onwardstate.com/2017/04/03/michael-mauti-reveals-battle-with-ulcerative-colitis/ ... courage in the face of such a difficult disease can serve as a positive reminder for anyone dealing with ulcerative colitis, or ... Michael Mauti Reveals Battle With Ulcerative Colitis. https:// ... Michael Mauti Reveals Battle With Ulcerative Colitis. By Ethan ...

https://onwardstate.com/2017/04/03/michael-mauti-reveals-battle-with-ulcerative-colitis/

Upadacitinib, a JAK inhibitor, may help patients with moderate to severely active ulcerative colitis obtain long-term control of the condition. (nature.com)
Etrasimod, an investigational selective sphingosine 1-phosphate (S1P) receptor modulator, led to clinically meaningful improvements in patients with moderately to severely active ulcerative colitis (UC), according to an analysis of two randomized trials. (medpagetoday.com)
The purpose of this study is to evaluate efficacy of golimumab in inducing clinical remission as assessed by the Mayo score, in pediatric participants with moderately to severely active ulcerative colitis (UC). (clinicaltrials.gov)
Entyvio was approved by the FDA in 2014 as a biologic therapy for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD). (takeda.com)

Unlike ulcerative colitis, which affects only the inner surface of the large intestine, Crohn disease can cause inflammation in any part of the digestive system, and the inflammation extends deeper into the intestinal tissue. (medlineplus.gov)
This immune response may lead to chronic inflammation and the digestive problems characteristic of ulcerative colitis. (medlineplus.gov)
Certain genetic variations may make some individuals more prone to an overactive immune response to the bacteria and other microbes in the intestines, which may cause the chronic inflammation that occurs in ulcerative colitis. (medlineplus.gov)
Another possible explanation is that ulcerative colitis occurs when the immune system malfunctions and attacks the cells of the intestines, causing inflammation. (medlineplus.gov)
Ulcerative colitis is an inflammatory bowel disease that is characterized by chronic inflammation of the colon. (nature.com)
Ulcerative colitis is a chronic disease that affects the lining of the large intestine, causing inflammation and ulceration. (medicalnewstoday.com)
Ulcerative colitis occurs when the immune system attacks gut bacteria and the cells lining the colon, causing inflammation. (ucsfhealth.org)
2.Uncontrollable deterioration of IBD signs might lead to the necessity of surgery, or specialised surgical procedures that help curb the aggravation of ulcerative colitis signs and GI inflammation. (healthynewage.com)
Hence, experts continue to recommend total abstinence from alcohol , which leads to experiencing significant improvements in ulcerative colitis signs and gastrointestinal inflammation symptoms. (healthynewage.com)
Unlike Crohn's disease , which causes a patchy inflammation, ulcerative colitis progresses in a diffuse manner. (uchicagomedicine.org)
Ulcerative colitis usually starts with inflammation in the rectum, and continues in a diffuse manner to involve other parts of the large intestine. (uchicagomedicine.org)
So a patient who has ulcerative colitis will have a continuous inflammation of their large intestine. (uchicagomedicine.org)
Ulcerative colitis causes a type of inflammation that's a bit more superficial and confined to the mucosa, or the lining of the large intestine. (uchicagomedicine.org)
Ulcerative colitis (UC), on the other hand, is continuous inflammation of the whole colon. (pharmacytimes.com)
Ulcerative colitis may also cause problems such as arthritis , inflammation of the eye, liver disease ( fatty liver , hepatitis , cirrhosis , and primary sclerosing cholangitis ), osteoporosis , skin rashes, anemia , and kidney stones . (digitalnaturopath.com)
Ulcerative colitis occasionally causes eye inflammation which resolves when the colitis is treated. (digitalnaturopath.com)
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by persistent colon inflammation. (gale.com)
Ulcerative colitis (UC) is a chronic, idiopathic colon inflammation whose incidence is increasing globally [1]. (researchsquare.com)
Medical pot can treat the inflammation, lack of appetite, general pain and exhaustion reported by people with ulcerative colitis. (marijuanadoctors.com)
Ulcerative colitis is a disease that causes inflammation and sores (ulcers) in the lining of the large intestine, or colon. (houstonwehaveaproblemblog.com)
Ulcerative colitis is a chronic, relapsing inflammatory disease of the colon, and affected patients may exhibit inflammation from cecum to rectum (see the following image). (medscape.com)
It has been shown to aid in ailments such as rheumatoid arthritis, Crohn's disease, kidney inflammation, eye inflammation, ulcerative colitis, and much more. (naturalsociety.com)
Ulcerative colitis is usually treated with medicines that reduce the inflammation in your digestive system. (azurewebsites.net)
Ulcerative colitis is inflammation of the lower end of your digestive system, including your large bowel and rectum. (azurewebsites.net)
Ulcerative colitis (UC) is a disease that causes inflammation and sores, called ulcers, in the lining of the rectum and colon. (medlineplus.gov)

GSK.L , GSK ) has discontinued its Phase II clinical trial evaluating an anti-LAG3 cell depleting monoclonal antibody, GSK2831781, in patients with active ulcerative colitis. (rttnews.com)
For remission induction in patients with mildly to moderately active ulcerative colitis, 5-aminosalicylates (5-ASAs) at a dose of at least 2 g/day are recommended. (medscape.com)

Management of ulcerative colitis can require a combination of treatments targeting different pathways. (nature.com)
This guideline covers the management of ulcerative colitis in children, young people and adults. (bvsalud.org)

A variety of genetic and environmental factors are likely involved in the development of ulcerative colitis. (medlineplus.gov)
Special attention is paid to the involvement of sulfate- reducing bacteria in the development of ulcerative colitis. (muni.cz)
Simultaneous development of ulcerative colitis in the colon and sigmoid neovagina. (bvsalud.org)

When we treat ulcerative colitis, we often start with medicines that work on the lining of the bowel in an effective way. (uchicagomedicine.org)
August 29, 2022 -- Georgia State University researchers have discovered a new way to treat ulcerative colitis -- oral delivery of lipid nanoparticles that target the colon with nucleic acids. (scienceboard.net)
Also, some genetically engineered drugs also used to treat ulcerative colitis. (coherentmarketinsights.com)
Shortly thereafter, in 2018, the drug was approved by the FDA to treat ulcerative colitis. (drug-injury.com)

Clinical guidelines on the medical treatment of ulcerative colitis were published in January 2022 by the European Crohn's and Colitis Organization (ECCO) in the Journal of Crohn's and Colitis . (medscape.com)
Cite this: Ulcerative Colitis Medical Therapy Clinical Practice Guidelines (ECCO, 2022) - Medscape - Mar 01, 2022. (medscape.com)
They found that mice with acute ulcerative colitis that orally received novel lipid nanoparticles with interleukin-22 (IL-22) mRNA experienced faster healing than those without the targeted approach ( Biomaterials , August 3, 2022). (scienceboard.net)
Supported by an educational grant from AbbVie, Crohn's and Colitis Canada will extend 15 one-time scholarships of up to $5,000 to students living with Crohn's disease and ulcerative colitis who are entering into or currently attending a post-secondary educational institution for the fall semester of 2022. (ubc.ca)

Common symptoms of ulcerative colitis include diarrhea and bloody, frequent stools, but constipation can also affect some individuals. (medicalnewstoday.com)
Common symptoms of ulcerative colitis include frequent diarrhoea (which may be bloody), stomach aches and needing to go to the toilet a lot. (azurewebsites.net)

Primary non-response is more common in ulcerative colitis than in Crohn's disease, highlighting the need for alternative biologic agents and oral small molecules. (nature.com)
About 12 percent of people with ulcerative colitis have a close relative who has either the same condition or Crohn's disease. (ucsfhealth.org)
First, ulcerative colitis is still considered a more 'benign' disease than Crohn's disease. (bmj.com)
Finally, the use of antitumour necrosis factor antibodies in ulcerative colitis has been low because this treatment is considered to be less effective than in Crohn's disease. (bmj.com)
Because people with inflammatory bowel disease (IBD), like ulcerative colitis and Crohn's disease , have a much higher risk of both thromboses and osteoporosis , a team of researchers from McGill University in Montreal explored the idea that homocysteine excess may play an important role in this chronic gastrointestinal disease. (digitalnaturopath.com)
The disease can lead to colon cancer and related conditions of irritable bowel disease and ulcerative Crohn's disease. (planetherbs.com)
Making the distinction between ulcerative colitis disease, irritable bowel disease or ulcerative Crohn's disease is not so simple. (planetherbs.com)
The specific pathogenesis underlying inflammatory bowel disease is complex, and it is even more difficult to decipher the pathophysiology to explain for the similarities and differences between two of its major subtypes, Crohn's disease and ulcerative colitis (UC). (dovepress.com)
Originally designated by the passage of U.S. Senate Resolution 199, Awareness Week provides an opportunity for the inflammatory bowel disease (IBD) community to come together around a shared goal - to raise awareness and educate the public about IBD as part of our mission to achieve a future free of Crohn's disease and ulcerative colitis. (crohnscolitisfoundation.org)
Rebecca Kaplan is the Public Affairs and Social Media Manager for the Crohn's & Colitis Foundation and the caregiver of a Crohn's disease patient. (crohnscolitisfoundation.org)
Though ulcerative colitis differs its counterpart Crohn's Disease, both share symptoms that can be treated using medicinal cannabis. (marijuanadoctors.com)
Ulcerative colitis and Crohn's disease are the most common types of inflammatory bowel disease. (houstonwehaveaproblemblog.com)
Provention's mission is to in-license, transform and develop clinical-stage, or nearly clinical-stage, therapeutic candidates targeting the high morbidity, mortality and escalating costs of autoimmune and inflammatory diseases including: type 1 diabetes (T1D), Crohn's disease, ulcerative colitis, lupus, and certain life-threating viral diseases. (proventionbio.com)
Idiopathic inflammatory bowel disease : Crohn's disease and chronic ulcerative colitis, the past, present, and future prospectives / edited by A. B. R. Thomson for the Canadian Foundation of Ileitis and Colitis. (who.int)
Crohn's disease and ulcerative colitis, collectively referred to enrolled in a Health Maintenance Organization in 2017. (cdc.gov)
BACKGROUND: The occurrence of Crohn's disease (CD) and ulcerative colitis (UC) is shaped by environmental influences. (cdc.gov)
39 women had Crohn's disease, 49 ulcerative colitis and 1 IBD-unclassified. (bmj.com)
Do you have a history of ulcerative colitis or Crohn's disease? (curezone.org)
An increase in mucus in the stools can be associated with inflammatory bowel diseases such as Crohn's disease, ulcerative colitis, or colon cancer. (lifepositive.com)
Indeed, given the systemic manifestations of IBD, it's particularly likely rheumatologists will see patients with ulcerative colitis and Crohn's disease. (the-rheumatologist.org)
The epidemiology of IBD is fairly evenly split between ulcerative colitis and Crohn's disease, patients are typically young at the time of diagnosis (i.e., between 15-30 years old), and most patients with IBD don't have a family history of the condition, Dr. Rubin explained. (the-rheumatologist.org)
This association is more frequently observed in patients with Crohn's disease than those with ulcerative colitis. (the-rheumatologist.org)
In time, this discovery could be useful for individuals suffering from chronic inflammatory diseases such as Crohn's disease or ulcerative colitis. (aviesan.fr)
In France, nearly 200,000 individuals suffer from chronic inflammatory bowel disease, known as IBD, (specifically Crohn's disease and ulcerative colitis). (aviesan.fr)
Did you know that Crohn's disease and ulcerative colitis are most frequently diagnosed between the ages of 15 and 30, with the typical onset being in the early 20s? (ubc.ca)
A recent study found that 69% of people who had Crohn's disease or ulcerative colitis when they were young were delayed in completing their post-secondary education. (ubc.ca)
The AbbVie IBD Scholarship Program recognizes the obstacles faced by students living with Crohn's disease and ulcerative colitis and supports them in rising above their personal challenges in pursuit of their dreams. (ubc.ca)
Research efforts within the Pediatric Gastroenterology division include projects involving: inflammatory bowel disease (Crohn's disease and ulcerative colitis), feeding and swallowing disorders, nutritional disorders, eosinophilic esophagitis, liver disorders, and many more. (unc.edu)
Entyvio is critical to Takeda's portfolio for the treatment of patients living with gastrointestinal diseases that can be complex, debilitating and life-changing, such as ulcerative colitis and Crohn's disease, and expanding production at Brooklyn Park demonstrates our commitment to serving patients in the US and globally," said Uthra Sundaram, Head of Patient Value & Product Strategy, Takeda Pharmaceuticals. (takeda.com)
Risk of Dementia in Patients With Inflammatory Bowel Disease Do ulcerative colitis or Crohn's disease increase the risk of dementia? (medscape.com)
Crohn's disease and ulcerative colitis are the two main types of IBD. (cdc.gov)

Ulcerative colitis, often simply called colitis, is a chronic inflammatory disease of the large intestine (the colon) that affects its lining and causes small sores (ulcers) to form. (ucsfhealth.org)
Ulcerative colitis is a type of inflammatory bowel disease that affects the large intestine (the colon and rectum). (uchicagomedicine.org)
Ulcerative colitis is a condition that affects the large intestine. (uchicagomedicine.org)
Some people who have ulcerative colitis that involves just the bottom of their large intestine will also feel paradoxically constipated. (uchicagomedicine.org)
WDSU sports anchor Fletcher Mackel said Mauti told reporters that he will have surgery for ulcerative colitis, a chronic disease of the large intestine. (wdsu.com)
Irritable bowel disease and ulcerative colitis involve only the large intestine. (planetherbs.com)
Ulcerative colitis is a long-term condition where the lining of the large intestine or large bowel (colon or rectum) becomes inflamed. (nhsinform.scot)
Ulcerative Colitis Ulcerative colitis is a chronic inflammatory bowel disease in which the large intestine (colon) becomes inflamed and ulcerated (pitted or eroded), leading to flare-ups (bouts or attacks) of. (merckmanuals.com)

So, we're talking about a patient who has ulcerative colitis who's failed an anti-TNF, and this is the situation that currently, according to the FDA, we are allowed to use a JAK inhibitor. (reachmd.com)

We don't know the cause of ulcerative colitis, but we do know a lot about how to treat it. (uchicagomedicine.org)
The cause of ulcerative colitis (UC) is currently under examination. (medscape.com)

A 42-year-old man with a history of ulcerative colitis (UC), primary sclerosing cholangitis (PSC) and chronic sinusitis was referred to a rheumatologist to evaluate for a possible diagnosis of systemic vasculitis. (the-rheumatologist.org)

Here the authors design a therapy for ulcerative colitis based on a multitargeted genetic circuit to simultaneously target TNF-α, B7-1 and integrin α4, and show the therapy is effective in male mice with induced or spontaneous genetic colitis. (nature.com)
The two-decade old biologic gained recognition as the first advanced therapy for ulcerative colitis. (prlog.org)

Many treatments for inflammatory bowel diseases (IBDs), such as ulcerative colitis, are delivered directly into the bloodstream and cause severe short- or long-term side effects. (scienceboard.net)

What causes ulcerative colitis? (houstonwehaveaproblemblog.com)
Experts are not sure what causes ulcerative colitis. (houstonwehaveaproblemblog.com)
It's not clear what causes ulcerative colitis. (azurewebsites.net)

Ulcerative colitis (UC) is one of the two major types of inflammatory bowel disease (IBD), along with Crohn disease (CD). (medscape.com)
Unlike Crohn disease, which can affect any part of the gastrointestinal tract, ulcerative colitis characteristically involves the large bowel (see the image below). (medscape.com)
Ulcerative colitis and Crohn disease are the two main forms of inflammatory bowel disease. (pharmacytimes.com)
Ulcerative colitis (UC) is one of the idiopathic forms of inflammatory bowel disease (IBD), sharing this designation with Crohn disease (CD). (medscape.com)
It is believed that the 2 idiopathic forms of inflammatory bowel disease (IBD), ulcerative colitis and Crohn disease (CD), develop secondary to complex interactions among genetic predispositions, environmental risk factors, and the immune system. (medscape.com)
When Crohn disease affects the colon, it is called Crohn colitis. (merckmanuals.com)

In North America, ulcerative colitis affects approximately 40 to 240 in 100,000 people. (medlineplus.gov)
However, North America holds the largest share in the global ulcerative colitis market due to continuous improvements in drugs, increased uptake of medicines, awareness about treatment and increasing clinical research. (coherentmarketinsights.com)
The estimated annual incidence of ulcerative colitis in North America and Europe ranges from 4 to 20 per 100,000 individuals. (medscape.com)

Colazal has an average rating of 6.2 out of 10 from a total of 6 ratings for the treatment of Ulcerative Colitis. (drugs.com)
Compare all 119 medications used in the treatment of Ulcerative Colitis . (drugs.com)
Oral corticosteroids (CS) are the treatment of choice for moderate flares of ulcerative colitis (UC) in patients who are on 5-aminosalicylic acid (5ASA) maintenance therapy. (clinicaltrials.gov)
New data published by Vivisum Partners, LLC, a North Carolina market research firm, found that 44% of gastroenterologists identify Remicade's dosing as a key weakness that has opened the door for Entyvio to surpass it as the ideal ulcerative colitis treatment. (prlog.org)
The data identify which ulcerative colitis brands HCPs perceive as the most ideal treatment. (prlog.org)
With the addition of new medications and lack of comparative studies, the difficulty of how to accurately position them for the treatment of ulcerative colitis continues to increase. (reachmd.com)
And, you know, there are a lot of barriers, but the one that comes to mind to me is right now we have this increasing landscape of treatment modalities for patients with moderate to severe ulcerative colitis. (reachmd.com)
Treatment with anti-tumor necrosis factor (TNF) agents (infliximab, adalimumab, and golimumab) is recommended for remission induction in patients with moderate-to-severe ulcerative colitis who do not adequately respond to or cannot tolerate conventional therapy. (medscape.com)
Treatment with tofacitinib is recommended for remission induction in patients with moderate-to-severe ulcerative colitis who do not adequately respond to or cannot tolerate conventional therapy. (medscape.com)
NICE OKs biologics for the treatment of ulcerative colitis, changing its preliminary guidance that recommended against their use. (biopharminternational.com)
In a landmark decision, the National Institute for Health and Care Excellence (NICE) announced on Dec. 15, 2014 that it will improve access to treatment options for patients with moderate to severe ulcerative colitis (UC) and will recommend the use of biologics for the condition. (biopharminternational.com)
OCTAVE (Oral Clinical Trials for tofAcitinib in ulceratiVE colitis) Sustain is a 52-week, multicenter, randomized, double-blind, placebo-controlled, parallel group Phase 3 trial evaluating oral tofacitinib 5mg and 10mg twice daily vs. placebo as a maintenance treatment in 593 adults with moderately to severely active UC who previously completed and achieved clinical response in either the OCTAVE Induction 1 or OCTAVE Induction 2 studies. (empr.com)
APAC region will show high growth in ulcerative colitis market during forecast years (2017-2024), due to raising awareness about the treatment, changing lifestyle will cause to increase prevalence and incidence rate, entry of new drugs in the market also some companies losing their patent of ulcerative drugs in coming years, like Humira (adalimumab) lost its patent in 2016 and Remicade will lose its patent in 2018. (coherentmarketinsights.com)
A detailed explanation of treatment for ulcerative colitis is beyond the scope of this discussion. (medscape.com)
It is imperative to recognize that colectomy alone may be an inadequate surgical intervention in patients with ulcerative colitis and a colonic neovaginal graft and that a concomitant neovaginectomy may be integral in providing appropriate treatment . (bvsalud.org)
Some success has also been reported in the treatment of ulcerative colitis. (commonground.ca)
PN-943 is an orally delivered, gut-restricted alpha-4-beta-7 integrin specific antagonist peptide in development for the treatment of inflammatory bowel disease, with ulcerative colitis as the initial targeted indication. (pharmiweb.com)

IMSEAR at SEARO: Idiopathic ulcerative colitis. (who.int)
Idiopathic ulcerative colitis. (who.int)

Just yesterday I posted a piece that described new research from Purdue that holds great promise for treating and possibly curing inflammatory gut diseases like Crohn's, Ulcerative Colitis, and IBS by flooding the gut with beneficial metabolites that are normally created by gut bacteria but that these bacteria can't produce when they have been compromised. (panaceachronicles.com)
OLDWICK, N.J. , Oct. 23, 2018 / PRNewswire / -- Provention Bio, Inc. (Nasdaq: PRVB), a clinical-stage biopharmaceutical company focused on immune-mediated diseases, announced today that it has completed enrollment in the Phase 1b clinical trial of PRV-300 in patients with moderate-to-severe ulcerative colitis (UC). (proventionbio.com)
Furthermore, workers were informed that sarcoidosis and ulcerative colitis are not occupationally related diseases. (cdc.gov)

The patient was initially treated with oral and topical mesalamine with good response, and her colitis went into remission. (medscape.com)
Germinated barley prolongs remission in patients with ulcerative colitis. (greenmedinfo.com)
Plaintain seeds (psyllium) may be as effective as mesalamine to maintain remission in ulcerative colitis. (greenmedinfo.com)
A significant proportion of patients with ulcerative colitis will still have to undergo colectomy and overall half of the patients do not achieve sustained remission, leading to impairment of physical and mental health, social life, employment issues and sexual activity. (bmj.com)
Topical (rectal) 5-ASAs at a dose of at least 1 g/day are recommended to induce remission in active distal colitis. (medscape.com)
Monotherapy with thiopurines is recommended to maintain remission in patients who have steroid-dependent ulcerative colitis or cannot tolerate 5-ASAs. (medscape.com)
An anti-TNF agent (infliximab, adalimumab, or golimumab) is recommended to maintain remission in patients with ulcerative colitis in whom a response to induction therapy was achieved with the same drug. (medscape.com)
Ulcerative colitis (UC) is difficult to treat and standard therapy does not always induce remission. (curezone.com)

Fish oil fatty acid supplementation improves mild to moderate ulcerative colitis and reduces or eliminates the need for anti-inflammatory drugs in most patients. (greenmedinfo.com)
The purpose of this study is to determine the efficacy of high-dose corticosteroid pulses added to conventional oral corticosteroid course for moderate flares of ulcerative colitis. (clinicaltrials.gov)

Though Remicade's efficacy is not in question, gastroenterologists have more options to offer ulcerative colitis patients treatments with easier dosing schedules. (prlog.org)
We also look at the symptoms, history, and range of other treatments for ulcerative colitis. (marijuanadoctors.com)

Ulcerative colitis affects approximately 100 out of 100,000 people in the United States. (planetherbs.com)
Ulcerative colitis affects only the colon and rectum. (houstonwehaveaproblemblog.com)
Ulcerative colitis affects everyone differently. (houstonwehaveaproblemblog.com)

Ulcerative colitis is a chronic inflammatory bowel disease affecting the lining of the colon. (css.ch)

So, there was, you know, a little bit of concern that there may be increased risk of cardiovascular event and lipid increase with tofacitinib when it came out for rheumatoid arthritis and ulcerative colitis, and so the company was asked to go back and look at this question, and they looked at patients who had increased risk of a cardiovascular event. (reachmd.com)
Nine JAK inhibitors have now been approved by agencies around the world to treat rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, ulcerative colitis, atopic dermatitis, graft versus host disease, and myeloproliferative neoplasms. (nih.gov)

Los principales síntomas son DIARREA, HEMORRAGIA rectal, presencia de MOCO en la heces y DOLOR ABDOMINAL. (bvsalud.org)

I ended up in the hospital where they referred me to a gastroenterologist who confirmed the diagnosis of Ulcerative Colitis. (rxisk.org)
If you or someone close to you have received an ulcerative colitis diagnosis, you probably want to learn as much as you can about it. (marijuanadoctors.com)
The doctor confirmed that right now Sophie has ulcerative colitis with a possible later diagnosis of Chrohn's. (houstonwehaveaproblemblog.com)
Participant has severe extensive colitis, diagnosis of CD, indeterminate colitis, presence or history of a fistula consistent with CD, microscopic colitis, radiation colitis, or ischemic colitis. (who.int)

You proceeded to perform a diagnostic colonoscopy to re-evaluate her disease and found that she had moderately severe colitis (Mayo Score 2) with marked erythema, absent vascular pattern, friability, and erosions from the anus to the rectosigmoid colon, 20 cm from the anus. (medscape.com)
Ulcerative colitis is a type of inflammatory bowel disease (IBD). (ucsfhealth.org)
Immutep noted that GSK2831781 has also been explored in another autoimmune disease beyond ulcerative colitis. (rttnews.com)
Ulcerative Colitis (UC) is another form of inflammatory bowel disease (IBS). (centerwatch.com)
Mauti's courage in the face of such a difficult disease can serve as a positive reminder for anyone dealing with ulcerative colitis, or a similar condition like Crohn's, to keep pursuing their dreams. (onwardstate.com)
DSS caused severe colitis in mice treated or treated with CCl 4 , as evident from the elevation of disease activity index (DAI), histological abnormalities, and increased pro-inflammatory cytokines (TNF-α, IFN-γ, and IL-17A). (frontiersin.org)
Ulcerative Colitis is an autoimmune disease where one develops bleeding ulcers in the colon along with fever, weakness, anemia due to the blood loss and weight loss. (rxisk.org)
The simple clinical colitis activity index (SCCAI) is a purely clinical index to evaluate UC disease activity and has demonstrated good correlation with the disease stage [5, 6]. (researchsquare.com)
Ulcerative colitis can also cause other problems, such as joint pain, eye problems, or liver disease. (houstonwehaveaproblemblog.com)
A number of not rare and sometimes inaugural complications add burden to the medical and surgical care of these patients: severe colitis, fistula, stenosis, cancerous degeneration with a risk 18 times higher than in general population after 20 years of progression of a pancolitic form of the disease. (ulcertalk.com)
Ulcerative colitis is the most common form of inflammatory bowel disease (IBD). (proventionbio.com)
The incidence and prevalence of IBD is increasing globally, and 556 for ulcerative colitis) were used for hospitalizations and although the disease has little impact on mortality, the before October 1, 2015, and ICD-10-CM codes for those number of older adults with IBD is expected to increase as the on or after that date. (cdc.gov)

Background: Although China has a large population and increasing incidence of ulcerative colitis (UC), data on pregnancy outcomes in women with UC are insufficient and the relationship between simple clinical colitis activity index (SCCAI) and pregnancy outcomes has rarely been studied. (researchsquare.com)

Ulcerative colitis involves only the colonic mucosa , and the lesions are uniform and continuous with no areas of normal tissue interspersed between the diseased mucosa. (digitalnaturopath.com)
Colonic and neovaginal biopsies demonstrated active colitis with diffuse ulcerations, consistent with ulcerative colitis . (bvsalud.org)

About 30% of adults, when they're diagnosed with ulcerative colitis, will have the entire colon affected by this, and 30% will have just the rectum inflamed. (uchicagomedicine.org)
And one of the things we've learned about treating ulcerative colitis, is that most of the symptoms people experience with ulcerative colitis are related to that inflamed rectum. (uchicagomedicine.org)
Because of its limited extent (usually less than the six inches of the rectum), ulcerative proctitis tends to be a milder form of ulcerative colitis . (digitalnaturopath.com)

Past and ongoing therapeutic concepts for ulcerative colitis have only been moderately successful. (bmj.com)

The most common symptoms of ulcerative colitis are abdominal pain and cramping and frequent diarrhea, often with blood, pus, or mucus in the stool. (medlineplus.gov)
Ulcerative colitis (UC) symptoms like diarrhea, pain, and fatigue can require you to make some adjustments to your sex life. (healthline.com)
Dehydration occurs in patients with severe diarrhea as seen in ulcerative colitis . (digitalnaturopath.com)
Ulcerative colitis, however, is associated with pain and bloody diarrhea. (planetherbs.com)
He did, however, exhibit the severe bleeding, diarrhea and pain characterized by advanced and severe ulcerative colitis. (planetherbs.com)

Management of refractory ulcerative colitis (UC) experiencing primary non-response or loss of response to biologics is a critical issue. (wjgnet.com)
We report on the youngest described case in which a patient developed ulcerative colitis refractory to medical therapy with simultaneous involvement of a sigmoid neovagina requiring total proctocolectomy and neovaginectomy. (bvsalud.org)

Germinated barley significantly reduces clinical symptoms of ulcerative colitis. (greenmedinfo.com)
The analysis contained in Ulcerative Colitis Rational Brand Perceptions shows that gastroenterologists rank Remicade poorly in three key clinical attributes: dosing, safety and tolerability. (prlog.org)
The findings in Vivisum's research offers a quantitative assessment of gastroenterologists' perceptions of ulcerative colitis brands' clinical benefits. (prlog.org)
The Phase 1b clinical trial of PRV-300 ( P rovention Ul cerative colitis S afety, pharmacokinetic and pharmacodynamic E valuation or PULSE) was initiated in the first quarter of 2018 following the in-licensing of the drug from Janssen in the second quarter of 2017. (proventionbio.com)

New Orleans Saints linebacker Michael Mauti revealed Tuesday he's undergoing surgery for ulcerative colitis and will be out the rest of the season. (wdsu.com)
We know that [biologics] can be life-transforming for people who live with these extremely debilitating symptoms, and who have had problems or no success with other tretaments and may be facing surgery," said Helen Terry, director of policy at Crohn's and Colitis UK, in a press release. (biopharminternational.com)
I started suffering from Ulcerative Colitis after I had surgery for hemorrhoids about two years ago. (rxisk.org)
My own assessment is that the stress from the surgery triggered my body to develop Colitis. (rxisk.org)
I told the doctor that I didn't want to go through another surgery knowing that my first surgery was responsible for the colitis. (rxisk.org)

especially in people whose entire colon is inflamed and in people who have had ulcerative colitis for 8 or more years. (medlineplus.gov)
Ulcerative colitis is more common in whites and people of eastern and central European (Ashkenazi) Jewish descent than among people of other ethnic backgrounds. (medlineplus.gov)
However, there are some ways in which people with ulcerative colitis can remedy constipation . (medicalnewstoday.com)
There are many ways to treat constipation in people with ulcerative colitis, depending on the severity of the symptoms and the person's lifestyle. (medicalnewstoday.com)
If diet, hydration, and exercise do not ease symptoms, some people with ulcerative colitis may find relief from constipation by taking over-the-counter (OTC) laxatives. (medicalnewstoday.com)
Most people with colitis are diagnosed before the age of 30, although the condition can develop at any time of life, from childhood to middle age and beyond. (ucsfhealth.org)
The situation gets trickier and more complex for people who have other conditions that concern the digestive apparatus such as when ulcerative colitis patients consume a substantial amount of alcohol each day. (healthynewage.com)
People with ulcerative colitis that's active they have many trips to the toilet, but actually very little might come out for most of those, or they may just see mucus or blood. (uchicagomedicine.org)
Ulcerative colitis can affect people of any age, but most people who have it are diagnosed before the age of 30. (houstonwehaveaproblemblog.com)
Ulcerative colitis is not caused by stress, as people thought in the past. (houstonwehaveaproblemblog.com)
You are more likely to get ulcerative colitis if other people in your family have it. (houstonwehaveaproblemblog.com)
About 5 to 10 out of 100 people with ulcerative colitis have symptoms all the time. (houstonwehaveaproblemblog.com)
People who have ulcerative colitis for 8 years or longer have a greater chance of getting colon cancer.2 Talk to your doctor about your need for cancer screening. (houstonwehaveaproblemblog.com)
People with ulcerative colitis should have more frequent tests for polyps and colorectal cancer than people at average risk. (ulcertalk.com)
There are some private clinics abroad that are using manual lymphatic drainage (MLD) as a therapy for helping people with Ulcerative Colitis. (lymphoedemacanada.com)
It aims to help professionals to provide consistent high-quality care and it highlights the importance of advice and support for people with ulcerative colitis. (bvsalud.org)

In this article, learn more about the link between ulcerative colitis and constipation and get some tips on how to manage this symptom. (medicalnewstoday.com)
Once you have your card, you can visit dispensaries and purchase the products that suit your ulcerative colitis symptom needs. (marijuanadoctors.com)

The inheritance pattern of ulcerative colitis is unknown because many genetic and environmental factors are likely to be involved. (medlineplus.gov)
The exact cause for ulcerative colitis is unknown, though possible reasons are may be genetic factors, environmental changes, or weakened immune system. (coherentmarketinsights.com)

Even though the inheritance pattern of this condition is unclear, having a family member with ulcerative colitis increases the risk of developing the condition. (medlineplus.gov)
Ulcerative colitis increases the risk of colorectal cancer. (ulcertalk.com)

There are different types of ulcerative colitis, but the most common form is distal ulcerative colitis. (medicalnewstoday.com)
In distal ulcerative colitis, the symptoms only affect the left side of the colon. (medicalnewstoday.com)

Patients with ulcerative colitis may absorb excess copper in their intestinal tissues which can lead to intestinal disorders, impaired healing and reduced resistance to infections. (digitalnaturopath.com)

It's also thought that environmental factors - such as viruses, bacteria or other antigens - may trigger the immune system activity that results in colitis. (ucsfhealth.org)
Immune Infiltration of Ulcerative Colitis and Detection of the m6A Subtype. (gale.com)
One theory proposes that ulcerative colitis occurs as a direct result of an aberrant immune response to "gut luminal antigen" in a genetically susceptible host. (medscape.com)

Ulcerative colitis can cause bloody, watery or mucousy bowel movements which may consist only of blood and pus. (digitalnaturopath.com)

According to the study of CCFA, industrialized countries have highest incidence rate for ulcerative colitis. (coherentmarketinsights.com)
Due to changing diet and lifestyle pattern, the emerging economies will show high growth rate in incidence rate of ulcerative colitis in the near future. (coherentmarketinsights.com)
Ulcerative colitis (UC) has 2 incidence peaks, one in adolescents and young adults and the other in middle-aged men and women. (medscape.com)
Since World War II, the incidence of ulcerative colitis has increased. (medscape.com)

Using medical marijuana for ulcerative colitis could significantly alleviate your symptoms. (marijuanadoctors.com)

Anatomy12

Organisms7

Diseases30

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment11

Phenomena and Processes1

Health Care1

Histocompatibility antigens in inflammatory bowel disease. Their clinical significance and their association with arthropathy with special reference to HLA-B27 (W27). (1/3046)

Expression of nitric oxide synthase in inflammatory bowel disease is not affected by corticosteroid treatment. (2/3046)

Perioperative growth hormone treatment and functional outcome after major abdominal surgery: a randomized, double-blind, controlled study. (3/3046)

Biased JH usage in plasma cell immunoglobulin gene sequences from colonic mucosa in ulcerative colitis but not in Crohn's disease. (4/3046)

Sulphation and secretion of the predominant secretory human colonic mucin MUC2 in ulcerative colitis. (5/3046)

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. (6/3046)

The systemic load and efficient delivery of active 5-aminosalicylic acid in patients with ulcerative colitis on treatment with olsalazine or mesalazine. (7/3046)

Is maintenance therapy always necessary for patients with ulcerative colitis in remission? (8/3046)

Colitis

Colitis, Ulcerative

Colitis, Ischemic

Colitis, Microscopic

Dextran Sulfate

Colitis, Collagenous

Colon

Trinitrobenzenesulfonic Acid

Colitis, Lymphocytic

Crohn Disease

Intestinal Mucosa

Inflammatory Bowel Diseases

Mesalamine

Rectum

Sulfasalazine

Peroxidase

Gastrointestinal Agents

Colectomy

Proctocolectomy, Restorative

Disease Models, Animal

Colonoscopy

Dysentery, Amebic

Ileostomy

Administration, Rectal

Enterocolitis, Pseudomembranous

Pouchitis

Mice, Inbred C57BL

Enterocolitis

Mice, Knockout

Diarrhea

Colonic Pouches

Acetic Acid

Intestines

Probiotics

Interleukin-10

Cytokines

Cecum

Citrobacter rodentium

Ileitis

Feces

Helicobacter hepaticus

Mice, Inbred BALB C

Anti-Inflammatory Agents, Non-Steroidal

Megacolon, Toxic

Ileum

Oxazolone

Biopsy

Clostridium difficile

Inflammation

Colon, Sigmoid

Chronic Disease

Sigmoidoscopy

Colonic Diseases

Proctitis

Intestine, Large

Cholangitis, Sclerosing

Mucous Membrane

Azathioprine

Colonic Neoplasms

Proctocolitis

Acute Disease

Prednisolone

Tumor Necrosis Factor-alpha

Dinitrofluorobenzene

Gastrointestinal Hemorrhage

Bacterial Translocation

Mesentery

Clostridium Infections

Collagen Diseases

CD4-Positive T-Lymphocytes

Severity of Illness Index

Ulcer

Mucin-2

Administration, Oral

Histocompatibility antigens in inflammatory bowel disease. Their clinical significance and their association with arthropathy with special reference to HLA-B27 (W27). (1/3046)

Expression of nitric oxide synthase in inflammatory bowel disease is not affected by corticosteroid treatment. (2/3046)

Perioperative growth hormone treatment and functional outcome after major abdominal surgery: a randomized, double-blind, controlled study. (3/3046)

Biased JH usage in plasma cell immunoglobulin gene sequences from colonic mucosa in ulcerative colitis but not in Crohn's disease. (4/3046)

Sulphation and secretion of the predominant secretory human colonic mucin MUC2 in ulcerative colitis. (5/3046)

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. (6/3046)

$DSpace at EWHA: The prevalence and efficacy of ganciclovir on steroid-refractory ulcerative colitis with cytomegalovirus...$ DSpace at EWHA: The prevalence and efficacy of ganciclovir on steroid-refractory ulcerative colitis with cytomegalovirus...

$Predictive factors of poor response to intravenous cyclosporine in steroid-refractory ulcerative colitis. - Semantic Scholar$ Predictive factors of poor response to intravenous cyclosporine in steroid-refractory ulcerative colitis. - Semantic Scholar