Disturbances in mental processes related to learning, thinking, reasoning, and judgment.
Intellectual or mental process whereby an organism obtains knowledge.
A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
Those disorders that have a disturbance in mood as their predominant feature.
Persistent and disabling ANXIETY.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)
Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)
A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.
A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.
An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
Disorders related to substance abuse.
A set of cognitive functions that controls complex, goal-directed thought and behavior. Executive function involves multiple domains, such as CONCEPT FORMATION, goal management, cognitive flexibility, INHIBITION control, and WORKING MEMORY. Impaired executive function is seen in a range of disorders, e.g., SCHIZOPHRENIA; and ADHD.
Any behavior caused by or affecting another individual, usually of the same species.
Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The ability to attribute mental states (e.g., beliefs, desires, feelings, intentions, thoughts, etc.) to self and to others, allowing an individual to understand and infer behavior on the basis of the mental states. Difference or deficit in theory of mind is associated with ASPERGER SYNDROME; AUTISTIC DISORDER; and SCHIZOPHRENIA, etc.
Study of mental processes and behavior of schizophrenics.
The perceiving of attributes, characteristics, and behaviors of one's associates or social groups.
Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.
A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)
The feeling-tone accompaniment of an idea or mental representation. It is the most direct psychic derivative of instinct and the psychic representative of the various bodily changes by means of which instincts manifest themselves.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)
A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)
Those affective states which can be experienced and have arousing and motivational properties.
An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Conditions characterized by disturbances of usual sleep patterns or behaviors. Sleep disorders may be divided into three major categories: DYSSOMNIAS (i.e. disorders characterized by insomnia or hypersomnia), PARASOMNIAS (abnormal sleep behaviors), and sleep disorders secondary to medical or psychiatric disorders. (From Thorpy, Sleep Disorders Medicine, 1994, p187)
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Remembrance of information for a few seconds to hours.
Learning the correct route through a maze to obtain reinforcement. It is used for human or animal populations. (Thesaurus of Psychological Index Terms, 6th ed)
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.
The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
The coordination of a sensory or ideational (cognitive) process and a motor activity.
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. The prefrontal cortex receives afferent fibers from numerous structures of the DIENCEPHALON; MESENCEPHALON; and LIMBIC SYSTEM as well as cortical afferents of visual, auditory, and somatic origin.
Standardized tests that measure the present general ability or aptitude for intellectual performance.
Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by a another medical condition, by the direct effects of a substance, or by another mental disorder. The symptoms must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)
Assessment of psychological variables by the application of mathematical procedures.
Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These disorders may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Capacity that enables an individual to cope with and/or recover from the impact of a neural injury or a psychotic episode.
Disorders related to or resulting from abuse or mis-use of alcohol.
Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
Disorders characterized by proliferation of lymphoid tissue, general or unspecified.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Theoretical representations that simulate psychological processes and/or social processes. These include the use of mathematical equations, computers, and other electronic equipment.
A prodromal phase of cognitive decline that may precede the emergence of ALZHEIMER DISEASE and other dementias. It may include impairment of cognition, such as impairments in language, visuospatial awareness, ATTENTION and MEMORY.
Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge.
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
A direct form of psychotherapy based on the interpretation of situations (cognitive structure of experiences) that determine how an individual feels and behaves. It is based on the premise that cognition, the process of acquiring knowledge and forming beliefs, is a primary determinant of mood and behavior. The therapy uses behavioral and verbal techniques to identify and correct negative thinking that is at the root of the aberrant behavior.
Standardized clinical interview used to assess current psychopathology by scaling patient responses to the questions.
The time from the onset of a stimulus until a response is observed.
The ability to understand and manage emotions and to use emotional knowledge to enhance thought and deal effectively with tasks. Components of emotional intelligence include empathy, self-motivation, self-awareness, self-regulation, and social skill. Emotional intelligence is a measurement of one's ability to socialize or relate to others.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994)
A learning situation involving more than one alternative from which a selection is made in order to attain a specific goal.
Modifying, carrying, or manipulating an item external to itself by an animal, before using it to effect a change on the environment or itself (from Beck, Animal Tool Behavior, 1980).
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The observable response of a man or animal to a situation.
Acquired or developmental conditions marked by an impaired ability to comprehend or generate spoken forms of language.
Neurotic reactions to unusual, severe, or overwhelming military stress.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Behaviors which are at variance with the expected social norm and which affect other individuals.
The observable response an animal makes to any situation.
A directed conversation aimed at eliciting information for psychiatric diagnosis, evaluation, treatment planning, etc. The interview may be conducted by a social worker or psychologist.
A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.
Includes two similar disorders: oppositional defiant disorder and CONDUCT DISORDERS. Symptoms occurring in children with these disorders include: defiance of authority figures, angry outbursts, and other antisocial behaviors.
Elements of limited time intervals, contributing to particular results or situations.
Standardized tests designed to measure abilities, as in intelligence, aptitude, and achievement tests, or to evaluate personality traits.
Conditions characterized by deficiencies of comprehension or expression of written and spoken forms of language. These include acquired and developmental disorders.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.
The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE.
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Disorders in which the symptoms are distressing to the individual and recognized by him or her as being unacceptable. Social relationships may be greatly affected but usually remain within acceptable limits. The disturbance is relatively enduring or recurrent without treatment.
Mental activity, not predominantly perceptual, by which one apprehends some aspect of an object or situation based on past learning and experience.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
Learning to respond verbally to a verbal stimulus cue.
The scientific disciplines concerned with the embryology, anatomy, physiology, biochemistry, pharmacology, etc., of the nervous system.
The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.
Reactions of an individual or groups of individuals with relation to the immediate surrounding area including the animate or inanimate objects within that area.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A meshlike structure composed of interconnecting nerve cells that are separated at the synaptic junction or joined to one another by cytoplasmic processes. In invertebrates, for example, the nerve net allows nerve impulses to spread over a wide area of the net because synapses can pass information in any direction.
A verbal or nonverbal means of communicating ideas or feelings.
A personality disorder in which there are oddities of thought (magical thinking, paranoid ideation, suspiciousness), perception (illusions, depersonalization), speech (digressive, vague, overelaborate), and behavior (inappropriate affect in social interactions, frequently social isolation) that are not severe enough to characterize schizophrenia.
Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
A psychological theory based on dimensions or categories used by a given person in describing or explaining the personality and behavior of others or of himself. The basic idea is that different people will use consistently different categories. The theory was formulated in the fifties by George Kelly. Two tests devised by him are the role construct repertory test and the repertory grid test. (From Stuart Sutherland, The International Dictionary of Psychology, 1989)
The reciprocal interaction of two or more persons.
Marked impairments in the development of motor coordination such that the impairment interferes with activities of daily living. (From DSM-V)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Conceptual functions or thinking in all its forms.
A disorder associated with three or more of the following: eating until feeling uncomfortably full; eating large amounts of food when not physically hungry; eating much more rapidly than normal; eating alone due to embarrassment; feeling of disgust, DEPRESSION, or guilt after overeating. Criteria includes occurrence on average, at least 2 days a week for 6 months. The binge eating is not associated with the regular use of inappropriate compensatory behavior (i.e. purging, excessive exercise, etc.) and does not co-occur exclusively with BULIMIA NERVOSA or ANOREXIA NERVOSA. (From DSM-IV, 1994)
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. (DSM-IV)
Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
Neural tracts connecting one part of the nervous system with another.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
Sudden temporary alterations in the normally integrative functions of consciousness.
Non-invasive methods of visualizing the CENTRAL NERVOUS SYSTEM, especially the brain, by various imaging modalities.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
The knowledge or perception that someone or something present has been previously encountered.
A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma's Oral Pathology, 6th ed, pp577-600)
Adaptation of the person to the social environment. Adjustment may take place by adapting the self to the environment or by changing the environment. (From Campbell, Psychiatric Dictionary, 1996)
Observable changes of expression in the face in response to emotional stimuli.
Stress wherein emotional factors predominate.
A disorder whose predominant feature is a loss or alteration in physical functioning that suggests a physical disorder but that is actually a direct expression of a psychological conflict or need.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
The awareness of the spatial properties of objects; includes physical space.
The determination and evaluation of personality attributes by interviews, observations, tests, or scales. Articles concerning personality measurement are considered to be within scope of this term.
The science and art of collecting, summarizing, and analyzing data that are subject to random variation. The term is also applied to the data themselves and to the summarization of the data.
Check list, usually to be filled out by a person about himself, consisting of many statements about personal characteristics which the subject checks.
The detailed examination of observable activity or behavior associated with the execution or completion of a required function or unit of work.
Includes both producing and responding to words, either written or spoken.
An individual's objective and insightful awareness of the feelings and behavior of another person. It should be distinguished from sympathy, which is usually nonobjective and noncritical. It includes caring, which is the demonstration of an awareness of and a concern for the good of others. (From Bioethics Thesaurus, 1992)
A component of the NATIONAL INSTITUTES OF HEALTH concerned with research, overall planning, promoting, and administering mental health programs and research. It was established in 1949.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
A functional relationship between psychological phenomena of such nature that the presence of one tends to evoke the other; also, the process by which such a relationship is established.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
A characteristic symptom complex.
Tests designed to measure intellectual functioning in children and adults.
Conditions characterized by language abilities (comprehension and expression of speech and writing) that are below the expected level for a given age, generally in the absence of an intellectual impairment. These conditions may be associated with DEAFNESS; BRAIN DISEASES; MENTAL DISORDERS; or environmental factors.
Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
Common name for the largest birds in the order PASSERIFORMES, family Corvidae. These omnivorous black birds comprise most of the species in the genus Corvus, along with ravens and jackdaws (which are often also referred to as crows).
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The physical activity of a human or an animal as a behavioral phenomenon.
The selecting and organizing of visual stimuli based on the individual's past experience.
Disorders of verbal and nonverbal communication caused by receptive or expressive LANGUAGE DISORDERS, cognitive dysfunction (e.g., MENTAL RETARDATION), psychiatric conditions, and HEARING DISORDERS.
The performance of the basic activities of self care, such as dressing, ambulation, or eating.
The process whereby a representation of past experience is elicited.
The tendency to explore or investigate a novel environment. It is considered a motivation not clearly distinguishable from curiosity.
Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a catecholamine.
Obsessive, persistent, intense fear of open places.
The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.
The study of the precise nature of different mental tasks and the operations of the brain that enable them to be performed, engaging branches of psychology, computer science, philosophy, and linguistics. (Random House Unabridged Dictionary, 2d ed)
The process of discovering or asserting an objective or intrinsic relation between two objects or concepts; a faculty or power that enables a person to make judgments; the process of bringing to light and asserting the implicit meaning of a concept; a critical evaluation of a person or situation.
A person's view of himself.
The affective response to an actual current external danger which subsides with the elimination of the threatening condition.
Abnormalities of motor function that are associated with organic and non-organic cognitive disorders.
Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.
Disturbances considered to be pathological based on age and stage appropriateness, e.g., conduct disturbances and anaclitic depression. This concept does not include psychoneuroses, psychoses, or personality disorders with fixed patterns.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.
A state of harmony between internal needs and external demands and the processes used in achieving this condition. (From APA Thesaurus of Psychological Index Terms, 8th ed)
Those psychological characteristics which differentiate individuals from one another.
A disorder beginning in childhood whose essential features are persistent impairment in reciprocal social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities. These symptoms may limit or impair everyday functioning. (From DSM-5)
Observable manifestations of impaired psychological functioning.
Cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs. These include spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body.
A false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one's associates.
Principles applied to the analysis and explanation of psychological or behavioral phenomena.
An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
Agents that are used to treat bipolar disorders or mania associated with other affective disorders.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
Aryl CYCLOPENTANES that are a reduced (protonated) form of INDENES.
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.
Evaluation of the level of physical, physiological, or mental functioning in the older population group.
The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Methods for visualizing REGIONAL BLOOD FLOW, metabolic, electrical, or other physiological activities in the CENTRAL NERVOUS SYSTEM using various imaging modalities.
A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.
The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.
The interference with or prevention of a behavioral or verbal response even though the stimulus for that response is present; in psychoanalysis the unconscious restraining of an instinctual process.
One of the convolutions on the medial surface of the CEREBRAL HEMISPHERES. It surrounds the rostral part of the brain and CORPUS CALLOSUM and forms part of the LIMBIC SYSTEM.
Those factors which cause an organism to behave or act in either a goal-seeking or satisfying manner. They may be influenced by physiological drives or by external stimuli.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
The act of "taking account" of an object or state of affairs. It does not imply assessment of, nor attention to the qualities or nature of the object.
The co-existence of a substance abuse disorder with a psychiatric disorder. The diagnostic principle is based on the fact that it has been found often that chemically dependent patients also have psychiatric problems of various degrees of severity.
A collective expression for all behavior patterns acquired and socially transmitted through symbols. Culture includes customs, traditions, and language.
Educational attainment or level of education of individuals.
Acquired or developmental cognitive disorders of AUDITORY PERCEPTION characterized by a reduced ability to perceive information contained in auditory stimuli despite intact auditory pathways. Affected individuals have difficulty with speech perception, sound localization, and comprehending the meaning of inflections of speech.
A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
An act performed without delay, reflection, voluntary direction or obvious control in response to a stimulus.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
Maladaptive reactions to identifiable psychosocial stressors occurring within a short time after onset of the stressor. They are manifested by either impairment in social or occupational functioning or by symptoms (depression, anxiety, etc.) that are in excess of a normal and expected reaction to the stressor.
A heterogeneous group of inherited metabolic disorders marked by absent or dysfunctional PEROXISOMES. Peroxisomal enzymatic abnormalities may be single or multiple. Biosynthetic peroxisomal pathways are compromised, including the ability to synthesize ether lipids and to oxidize long-chain fatty acid precursors. Diseases in this category include ZELLWEGER SYNDROME; INFANTILE REFSUM DISEASE; rhizomelic chondrodysplasia (CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC); hyperpipecolic acidemia; neonatal adrenoleukodystrophy; and ADRENOLEUKODYSTROPHY (X-linked). Neurologic dysfunction is a prominent feature of most peroxisomal disorders.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
A scale comprising 18 symptom constructs chosen to represent relatively independent dimensions of manifest psychopathology. The initial intended use was to provide more efficient assessment of treatment response in clinical psychopharmacology research; however, the scale was readily adapted to other uses. (From Hersen, M. and Bellack, A.S., Dictionary of Behavioral Assessment Techniques, p. 87)
The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community.
Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Cognitive recovery after severe head injury. 3. WAIS verbal and performance IQs as a function of post-traumatic amnesia duration and time from injury. (1/8507)

Two studies are reported are reported in which severely head-injured patients were followed up and Verbal (VIQ) and Performance (PIQ) IQs obtained on the Wechsler Adult Intelligence Scale at four intervals after injury. In the first study 51 patients were systematically followed, and results were based upon serial testing. In the second study results were based on the earliest data available from an additional 98 patients who had not been followed so systematically, in order to introduce a control for the effects of practice. Patients in both studies were categorised into four groups of the severity of head injury based upon duration of post-traumatic amnesia (PTA). In both studies, VIQ level was found to be related to PTA duration at three months after injury, while PIQ was related to PTA duration at both three and six months. No such relationships were found at 12 and 30 months after injury. Results are discussed in the context of previous studies relating the outcome of head injury to the duration of PTA.  (+info)

Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial. (2/8507)

OBJECTIVES: To assess the effects of rivastigmine on the core domains of Alzheimer's disease. DESIGN: Prospective, randomised, multicentre, double blind, placebo controlled, parallel group trial. Patients received either placebo, 1-4 mg/day (lower dose) rivastigmine, or 6-12 mg/day (higher dose) rivastigmine. Doses were increased in one of two fixed dose ranges (1-4 mg/day or 6-12 mg/day) over the first 12 weeks with a subsequent assessment period of 14 weeks. SETTING: 45 centres in Europe and North America. PARTICIPANTS: 725 patients with mild to moderately severe probable Alzheimer's disease diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, and the criteria of the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association. OUTCOME MEASURES: Cognitive subscale of the Alzheimer's disease assessment scale, rating on the clinician interview based impression of change incorporating caregiver information scale, and the progressive deterioration scale. RESULTS: At the end of the study cognitive function had deteriorated among those in the placebo group. Scores on the Alzheimer's disease assessment scale improved in patients in the higher dose group when compared with patients taking placebo (P<0.05). Significantly more patients in the higher dose group had improved by 4 points or more than had improved in the placebo group (24% (57/242) v 16% (39/238)). Global function as rated by the clinician interview scale had significantly improved among those in the higher dose group compared with those taking placebo (P<0.001), and significantly more patients in the higher dose group showed improvement than did in the placebo group (37% (80/219) v 20% (46/230)). Mean scores on the progressive deterioration scale improved from baseline in patients in the higher dose group but fell in the placebo group. Adverse events were predominantly gastrointestinal, of mild to moderate severity, transient, and occurred mainly during escalation of the dose. 23% (55/242) of those in the higher dose group, 7% (18/242) of those in the lower dose group, and 7% (16/239) of those in the placebo group discontinued treatment because of adverse events. CONCLUSIONS: Rivastigmine is well tolerated and effective. It improves cognition, participation in activities of daily living, and global evaluation ratings in patients with mild to moderately severe Alzheimer's disease. This is the first treatment to show compelling evidence of efficacy in a predominantly European population.  (+info)

The Montefiore community children's project: a controlled study of cognitive and emotional problems of homeless mothers and children. (3/8507)

OBJECTIVES: This study compares the prevalence of emotional, academic, and cognitive impairment in children and mothers living in the community with those living in shelters for the homeless. METHOD: In New York City, 82 homeless mothers and their 102 children, aged 6 to 11, recruited from family shelters were compared to 115 nonhomeless mothers with 176 children recruited from classmates of the homeless children. Assessments included standardized tests and interviews. RESULTS: Mothers in shelters for the homeless showed higher rates of depression and anxiety than did nonhomeless mothers. Boys in homeless shelters showed higher rates of serious emotional and behavioral problems. Both boys and girls in homeless shelters showed more academic problems than did nonhomeless children. CONCLUSION: Study findings suggest a need among homeless children for special attention to academic problems that are not attributable to intellectual deficits in either children or their mothers. Although high rates of emotional and behavioral problems characterized poor children living in both settings, boys in shelters for the homeless may be particularly in need of professional attention.  (+info)

Attention and executive deficits in Alzheimer's disease. A critical review. (4/8507)

In this review we summarize the progress that has been made in the research on attentional and executive deficits in Alzheimer's disease. Like memory, attention is now recognized as consisting of subtypes that differ in their function and anatomical basis. We base our review upon a classification of three subtypes of attention: selective, sustained and divided. This model derives from lesion studies, animal electrophysiological recordings and functional imaging. We examine how these subcomponents of attention can be reconciled with neuropsychological models of attentional control, particularly the Supervisory Attentional System and the Central Executive System of Shallice and Baddeley, respectively. We also discuss the relationship of attention to the concept of executive function. Current evidence suggests that after an initial amnesic stage in Alzheimer's disease, attention is the first non-memory domain to be affected, before deficits in language and visuospatial functions. This is consistent with the possibility that difficulties with activities of daily living, which occur in even mildly demented patients, may be related to attentional deficits. It appears that divided attention and aspects of selective attention, such as set-shifting and response selection, are particularly vulnerable while sustained attention is relatively preserved in the early stages. The phenomenon of cognitive slowing in Alzheimer's disease and normal ageing emphasizes the need to discriminate quantitative changes in attention dysfunction from qualitative changes which may be specifically related to the disease process. The neuropathological basis of these attentional deficits remains unsettled, with two competing hypotheses: spread of pathology from the medial temporal to basal forebrain structures versus corticocortical tract disconnection. Finally we discuss the difficulties of comparing evidence across studies and look at the implications for the design of future studies and future directions that may be fruitful in the research on attention in Alzheimer's disease.  (+info)

Does vestibular stimulation activate thalamocortical mechanisms that reintegrate impaired cortical regions? (5/8507)

Caloric stimulation induced a transient reversal of multimodal hemispatial cognitive deficits in an 81-year-old woman with an acute left cerebral hemisphere stroke. The patient had unawareness of her right hand (asomatognosia), right-sided visual unawareness (hemineglect), aphasia and right-sided weakness (hemiplegia) prior to the stimulation. Transient improvements in impaired sensory, motor, linguistic and cognitive function developed within 30 s following application of the caloric stimulus and onset of horizontal nystagmus. The effect persisted for 3 min and ceased completely after 5 min. While several recent reports have described the capacity of caloric stimulation to transiently improve or reverse a wide range of attentional, cognitive and motor impairments, most examples are in right-hemisphere-damaged patients with long-standing brain injury. Typically, patients have been tested several months or years after the onset of the deficit. A possible mechanism for the temporary reintegration of multiple cognitive functions in this patient is discussed.  (+info)

Longer term quality of life and outcome in stroke patients: is the Barthel index alone an adequate measure of outcome? (6/8507)

OBJECTIVES: To consider whether the Barthel Index alone provides sufficient information about the long term outcome of stroke. DESIGN: Cross sectional follow up study with a structured interview questionnaire and measures of impairment, disability, handicap, and general health. The scales used were the hospital anxiety and depression scale, mini mental state examination, Barthel index, modified Rankin scale, London handicap scale, Frenchay activities index, SF36, Nottingham health profile, life satisfaction index, and the caregiver strain index. SETTING: South east London. SUBJECTS: People, and their identified carers, resident in south east London in 1989-90 when they had their first in a life-time stroke aged under 75 years. INTERVENTIONS: Observational study. MAIN OUTCOME MEASURES: Comparison and correlation of the individual Barthel index scores with the scores on other outcome measures. RESULTS: One hundred and twenty three (42%) people were known to be alive, of whom 106 (86%) were interviewed. The median age was 71 years (range 34-79). The mean interval between the stroke and follow up was 4.9 years. The rank correlation coefficients between the Barthel and the different dimensions of the SF36 ranged from r = 0.217 (with the role emotional dimension) to r = 0.810 (with the physical functioning dimension); with the Nottingham health profile the range was r = -0.189 (with the sleep dimension, NS) to r = -0.840 (with the physical mobility dimension); with the hospital and anxiety scale depression component the coefficient was r = -0.563, with the life satisfaction index r = 0.361, with the London handicap scale r = 0.726 and with the Frenchay activities index r = 0.826. CONCLUSIONS: The place of the Barthel index as the standard outcome measure for populations of stroke patients is still justified for long term follow up, and may be a proxy for different outcome measures intended for the assessment of other domains.  (+info)

Confusional state in stroke: relation to preexisting dementia, patient characteristics, and outcome. (7/8507)

BACKGROUND AND PURPOSE: Acute confusional state (ACS) is frequent in hospitalized stroke patients. We previously showed that 16% of patients admitted for a stroke have preexisting dementia. The extent to which preexisting cognitive decline is associated with a risk of ACS at the acute stage of stroke remains to be systematically examined. The aim of this study was to evaluate the prevalence of ACS in acute stroke patients, to study the influence of preexisting cognitive decline and other patient characteristics, and to evaluate the influence of ACS on outcome. METHODS: We diagnosed ACS using DSM-IV criteria and the Delirium Rating Scale with a cutoff of 10 in 202 consecutive stroke patients aged 40 years or older (median age, 75 years; range, 42 to 101 years). Cognitive functioning before stroke was assessed with the Informant Questionnaire on Cognitive Decline in the Elderly. RESULTS: Forty-nine stroke patients (24.3%; 95% CI, 18.3% to 30.2%) had an ACS during hospitalization. Using logistic regression analysis, we found preexisting cognitive decline (P=0.006) and metabolic or infectious disorders (P=0.008) to be independent predictors of ACS. Functional, but not vital, prognosis was worse in patients with ACS at discharge and 6 months after stroke. CONCLUSIONS: ACS occurs in one fourth of stroke patients older than 40 years. Its occurrence requires inquiry for a preexisting cognitive decline, which usually remains unrecognized in the absence of a systematic evaluation.  (+info)

Cognitive function and treatment of obstructive sleep apnea syndrome. (8/8507)

Among patients with obstructive sleep apnea syndrome (OSAS), impairment of cognitive function, i.e. deficits in memory, attention, and visuconstructive abilities are common. We applied different forms of treatment for patients with newly diagnosed OSAS in a randomized study with a one-year follow-up. Patients with BMI > 40 kg/m2 were excluded. After the initial diagnostic work-up, male patients were considered to be candidates for either nasal continuous airway pressure (nCPAP) (27 patients) or surgical treatment (uvulopalatopharyngoplasty with or without mandibular osteotomy) (23 patients). Within the groups, the patients were then randomized to active treatment (nCPAP/surgery) or to conservative management. Cognitive function and severity of OSAS were assessed prior to treatment and 3 and 12 months later. At 12 months, all patients on nCPAP had a normal ODI4 index (< 10), and were significantly less somnolent than their controls; 3/11 of the surgically treated patients had a normal ODI4 index. Daytime somnolence was significantly less severe in the surgically treated patients than in their controls. Cognitive function did not correlate importantly with daytime sleepiness or severity of OSAS; the best Pearson pairwise correlation coefficient was between ODI4 and the Bourdon-Wiersma (r = 0.36). Success in treatment of OSAS did not affect neuropsychological outcome. We concluded that the standard cognitive test battery is insufficiently sensitive to identify positive changes in patients with OSAS, especially among those with a high level of overall mental functioning.  (+info)

Results Among patients with MCI, greater severity of depressive symptoms was associated with greater global cognitive impairment, with a moderate effect size. A mediation analysis revealed that patients with MCI experiencing depressive symptoms may exhibit global cognitive impairment because their depressive symptoms were reducing their capacity for working memory, episodic memory and non-speed-based executive functions. A moderation analysis indicated that this effect was consistent across age, gender, years of education and APOE-e4 status for working memory and episodic memory, and was observed in patients with MCI older than 65 years for executive functions. In cognitively normal elderly adults and patients with AD, depressive symptoms were not associated with global cognitive impairment. ...
U.S., March 20 -- ClinicalTrials.gov registry received information related to the study (NCT03081429) titled A Prospective Cohort Study of Perioperative Covert Stroke and Postoperative Cognitive Dysfunction on March 10. Brief Summary: With the development of population aging, the incidence of covert stroke and cognitive dysfunction gradually increased. Currently, there is still lack of prospective cohort study with large sample size on the relationship between perioperative covert stroke and postoperative cognitive dysfunction. The investigators will perform a prospective cohort study. The aim of the study is to determine whether there is an association between perioperative covert stroke and postoperative cognitive dysfunction in elderly patients undergoing noncardiac surgery. Study Start Date: Study Type: Observational Condition: Anesthesia Postoperative Cognitive Dysfunction Covert Stroke Intervention: Not Provided Recruitment Status: Not yet recruiting Sponsor: Beijing Tiantan Hospital ...
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Washington D.C. [USA], June 10 (ANI): U.S. researchers have found that radiation therapy (RT) used for treating patients with brain tumors can alter neural networks and cause long-term cognitive impairment.
Long-term cognitive impairment is a significant public health problem. In the October 3 issue of the New England Journal of Medicine, the BRAIN-ICU
Background: Identifying persons at risk for cognitive decline may aid in early detection of persons at risk of dementia and to select those that would benefit most from therapeutic or preventive measures for dementia. Objective: In this study we aimed to validate whether cognitive decline in the general population can be predicted with multivariate data using a previously proposed supervised classification method: Disease State Index (DSI). Methods: We included 2,542 participants, non-demented and without mild cognitive impairment at baseline, from the population-based Rotterdam Study (mean age 60.9 ± 9.1 years). Participants with significant global cognitive decline were defined as the 5% of participants with the largest cognitive decline per year. We trained DSI to predict occurrence of significant global cognitive decline using a large variety of baseline features, including magnetic resonance imaging (MRI) features, cardiovascular risk factors, APOE-ε4 allele carriership, gait features, ...
This study aimed to assess the relationship between renal impairment and cognitive decline. Of the 3769 patients, 396 (10%) had cognitive impairment at the outset. After the 2-year follow-up, 194 participants (6.2%) developed new cognitive impairment. Multiple logistic regression analysis showed that moderate-to-severe impaired renal function was associated with incident cognitive impairment after 2 years in a large cohort of elderly subjects ...
Objective: Mini-mental state examination, a nonspecific measure of global cognitive function, and the clock drawing test, a very concise and specific measure of cognitive function, are among the most widely used screening tests for cognitive dysfunction. The present research aimed to examine the correspondence between MMSE and CDT scores. Methods: A total of ...
Objective: To use functional MRI )fMRI) to investigate whether hippocampal activation during a memory task can predict cognitive decline in individuals with mild cognitive impairment (MCI). Methods: 25 older individuals with MCI performed a visual scene encoding task during fMRI scanning, and were followed clinically for at least 4 years after scanning. A hypothesis driven analysis of fMRI data was performed. First, fMRI data were analysed at the group level to identify the regions of the hippocampal formation that were engaged by this memory task. Parameter estimates of each subjects memory related hippocampal activation )% signal change) were extracted and were analysed with a linear regression model to determine whether hippocampal activation predicted the degree or rate of cognitive decline, as measured by change in Clinical Dementia Rating Sum-of-Boxes )CDR-SB). Results: Over 5.9 (1.2) years of follow-up after scanning, subjects varied widely in degree and rate of cognitive decline (change ...
2017 The Authors Introduction High levels of amyloid ß (Aß) are associated with cognitive decline in cognitively normal (CN) older adults. This study investigated the nature of cognitive decline in healthy individuals who did not progress to mild cognitive impairment or dementia. Method Cognition was measured over 72 months and compared between low (Aß-) and high (Aß+) CN older adults (n = 335) who did not progress to mild cognitive impairment or dementia and who remained free of severe or uncontrolled systemic illness. Results Compared to the Aß- group, the Aß+ group showed no cognitive impairment at baseline but showed substantial decline in verbal learning, episodic memory, and attention over 72 months. Discussion Moderate cognitive decline, particularly for learning and memory, was associated with Aß+ in CN older adults in the absence of clinical disease progression and uncontrolled or serious comorbid illness.. ...
Although cognitive disabilities and intellectual disabilities are related, the terms refer to different effects and conditions. In this lesson, we...
Postoperative cognitive dysfunction (POCD) is a common postoperative complication experienced by patients aged 65 years and older, and these older adults comprise more than one third of the surgical patients in the USA. Because not everyone with a history of exposure to surgery and anesthesia develops POCD, there are likely major biological risk factors involved. There are important gaps in our knowledge regarding whether genetic makeup, biological sex, or other Alzheimers disease risk factors predispose older adults to developing POCD. We set out to determine whether biological sex and Apolipoprotein E-ε4 (APOE4) carrier status increase the risk of developing POCD in older adults. We performed a cohort analysis of 1033 participants of prospective longitudinal aging studies. Participants underwent regular cognitive test batteries and we compared the annual rate of change over time in various cognitive measures in the women exposed to surgery and general anesthesia compared to the men exposed to
Postoperative cognitive dysfunction (POCD) is a decline in cognitive function (especially in memory and executive functions) that may last from a few days to a few weeks after surgery. In rare cases, this disorder may persist for several months after major surgery. POCD is distinct from emergence delirium. It occurs most commonly in older patients and those with pre-existing cognitive impairment. The causes of POCD are not understood. It does not appear to be caused by lack of oxygen or impaired blood flow to the brain and is equally likely under regional and general anesthesia. It may be mediated by the bodys inflammatory response to surgery. POCD is common after cardiac surgery, and recent studies have now verified that POCD also exists after major non-cardiac surgery, although at a lower incidence. The risk of POCD increases with age, and the type of surgery is also important because there is a very low incidence associated with minor surgery. POCD is common in adult patients of all ages at ...
Postoperative cognitive decline (POCD) affects up to 50% of non-cardiac surgical patients greater than or equal to 65 years of age.. This study will test the hypothesis that preoperative presence of brain beta-amyloid plaques in non-demented subjects increases postoperative cognitive decline (POCD) in elderly subjects scheduled for hip or knee replacement.. The investigators hypothesize that preoperative beta-amyloid plaques will predict postoperative cognitive decline. ...
TY - JOUR. T1 - Subjective cognitive complaints and objective cognitive impairment in parkinsons disease. AU - Hong, Jin Yong. AU - Lee, Yoonju. AU - Sunwoo, Mun Kyung. AU - Sohn, Young H.. AU - Lee, Phil Hyu. PY - 2018/1. Y1 - 2018/1. N2 - Background and Purpose Subjective cognitive complaints (SCCs) are very common in patients with Parkinsons disease (PD). However, the relationship between SCCs and objective cognitive impairment is still unclear. This study aimed to determine whether SCCs are correlated with objective cognitive performance in patients with PD. Methods Totals of 148 cognitively normal patients, 71 patients with mild cognitive impairment (MCI), and 31 demented patients were recruited consecutively from a movement-disor-ders clinic. Their SCCs and cognitive performances were evaluated using the Cognitive Complaints Interview (CCI) and a comprehensive neuropsychological battery. Results The CCI score increased with age, duration of PD, and depression score, and was inversely ...
Major surgeries, such as cardiac or orthopaedic procedures in particular, expose the patient to extensive trauma, blood loss, and tissue injury; all of these factors effectively modulate the immune system to ultimately trigger an inflammatory response. Postoperative cognitive dysfunction (POCD), the condition being characterized by impairment of short and long-term memory, is one of common complicates following surgery. Recently, our data have demonstrated that neuroinflammation and microglia activation in the hippocampus following surgery are associated with cognitive decline. The aim of this thesis is to investigate the inflammatory signaling pathways specifically involved with POCD, with a particular interest between systemic inflammation and local inflammation in the brain following surgery. The data presented in this thesis introduce the general concepts and the involvement of inflammation in the etiology of cognitive dysfunctions using a mouse model of POCD. Upon the identification of ...
Objective : Performance validity tests (PVTs) are essential in neuropsychological evaluations; however, it has been questioned how PVTs function in the context of cognitive impairment, and whether cognitive impairment alone is sufficient to cause PVT failure. Further, there is concern that some clinicians will disregard failed PVTs due to their perception that failures represent false-positive errors secondary to cognitive impairment. This study examined patterns associated with cognitively impaired versus noncredible performance across a battery of PVTs and neuropsychological tests. Additionally, the impact of VA service-connection and disability-seeking status on test validity was investigated. Method : A mixed-clinical sample of 103 veterans were administered six PVTs and neuropsychological tests. Performance was compared across three groups: valid-cognitively unimpaired, valid-cognitively impaired, and noncredible. Results : Significant PVT score differences and failure rates emerged across ...
TY - JOUR. T1 - Mesial temporal tau is related to worse cognitive performance and greater neocortical tau load in amyloid-β-negative cognitively normal individuals. AU - Groot, Colin. AU - Doré, Vincent. AU - Robertson, Joanne. AU - Burnham, Samantha C.. AU - Savage, Greg. AU - Ossenkoppele, Rik. AU - Rowe, Christopher C.. AU - Villemagne, Victor L.. N1 - Funding Information: C.C.R. reports speaker honoraria from GE Healthcare and Avid Radiopharmaceuticals, consulting fees from Avid Radiopharmaceuticals, AstraZeneca, and Piramal Imaging, and research grants from Avid Radiopharmaceuticals, GE Healthcare, and Piramal Imaging all outside the scope of the submitted work. V.L.V. reports speaker honoraria from GE Healthcare, Piramal Imaging, and Avid Radiopharmaceuticals, and consulting fees from Lundbeck, AbbVie, Shanghai Green Valley Co, IXICO, and Hoffmann La Roche, all outside the scope of the submitted work. C.G., V.D., J.R., S.B., G.S., and R.O. report no disclosures. Funding Information: ...
Free download the The Mini-Mental State Exam (MMSE) 1.0 iPhone & iPad app (★★½,522 downloads),The Mini-Mental State Exam (MMSE) is the most widely used cognitive test for dementia in US clinical pract
Improving psychological well-being and cognitive health is now listed as the priority on the healthy aging agenda. Depression and cognitive impairment are great challenges for the elderly population. There have been numerous studies on depression and cognitive impairment and dementia. However, the neural correlates of depression and cognitive impairment have not yet been elucidated. With the development of neuroscience and relevant technologies, studies on anatomical and functional neural networks, neurobiological mechanisms of mood and cognition in old age will provide more insight into the potential diagnosis, prevention and intervention in depression and cognitive impairment. For example, longitudinal neuroimaging studies depicting the trajectories of patterns of structural and functional brain networks of mild cognitive impairment may provide potential imaging markers for the onset of dementia.Population-based studies have addressed the potential interaction between mood and cognitive impairment in
In this prospective cohort study of black and white adults in the United States aged 45 and older, free of stroke and baseline cognitive impairment, mid-range to high Lifes Simple 7 scores at baseline were associated with lower incidence of clinically relevant cognitive impairment on a 3-test measure of verbal learning, memory, and fluency. Rather than a dose-response pattern across the range of Lifes Simple 7 scores, we observed that associations with ICI were the same for the highest tertile of Lifes Simple 7 score and the middle tertile, relative to the lowest tertile. This pattern suggests that even intermediate levels of CVH are preferable to low levels of CVH. This is an encouraging message for population health promotion, because intermediate CVH is a more realistic target than ideal CVH for many individuals.. The purpose of the Lifes Simple 7 metric is to summarize several modifiable factors into a single score to promote and measure individual- and population-level improvements in ...
Postoperative cognitive dysfunction is the deterioration of cognitive performance after anesthesia and surgery, and manifests as impairments in short-term memory, concentration, language comprehension, and social integration skills ...
ACE-R - Addenbrooke's Cognitive Examination Revised. Looking for abbreviations of ACE-R? It is Addenbrooke's Cognitive Examination Revised. Addenbrooke's Cognitive Examination Revised listed as ACE-R
...Postoperative cognitive dysfunction is the deterioration of cognitive ......,Aspartic,acid,in,the,hippocampus:,A,biomarker,for,postoperative,cognitive,dysfunction,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Presbycusis-related tinnitus and cognitive impairment are common in the elderly and generate a massive burden on family and society. Except for age, the study explored the gender differences in the prevalence of the three diseases. We found that women have an advantage in maintaining better cognitive and auditory functions. Recent studies suggest the complex links among the three diseases. Peripheral hearing loss can affect sound coding and neural plasticity, which will lead to cognitive impairment and tinnitus. The deficits of the central nervous system, especially central auditory structures, can, in turn, cause the presbycusis. The interaction among three diseases indicated that comprehensive assessment, intervention and treatment in consideration of hearing loss, tinnitus and cognitive impairment are important to decay aging.
Author(s): Simon, Tony J; Wu, Zhongle; Avants, Brian; Zhang, Hui; Gee, James C; Stebbins, Glenn T | Abstract: BACKGROUND:Chromosome 22q11.2 deletion syndrome is one of the most common genetic causes of cognitive impairment and developmental disability yet little is known about the neural bases of those challenges. Here we expand upon our previous neurocognitive studies by specifically investigating the hypothesis that changes in neural connectivity relate to cognitive impairment in children with the disorder. METHODS:Whole brain analyses of multiple measures computed from diffusion tensor image data acquired from the brains of children with the disorder and typically developing controls. We also correlated diffusion tensor data with performance on a visuospatial cognitive task that taps spatial attention. RESULTS:Analyses revealed four common clusters, in the parietal and frontal lobes, that showed complementary patterns of connectivity in children with the deletion and typical controls. We interpreted
Background The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related decline in cognitive test performance varied among international cohort studies of cognitive aging. We also determined the extent to which sex, educational attainment, and apolipoprotein E ε4 allele (APOE*4) carrier status were associated with decline. Methods and findings We harmonized longitudinal data for 14 cohorts from 12 countries (Australia, Brazil, France, Greece, Hong Kong, Italy, Japan, Singapore, Spain, South Korea, United Kingdom, United States), for a total of 42,170 individuals aged 54-105 y (42% male), including 3.3% with dementia at baseline. The studies began between 1989 and 2011, with all but three ongoing, and each had 2-16 assessment waves (median = 3) and a follow-up duration of 2-15 y. We analyzed standardized Mini-Mental State Examination (MMSE) and memory
VP/VLBW individuals had significantly lower IQ scores than term-born individuals across all time points into adulthood. Approximately 1 in 4 VP/VLBW adults had a severe cognitive impairment and mean differences between VP/VLBW and term-born individuals in IQ scores were partly explained by those with cognitive impairment. IQ scores were consistently found to be more stable from childhood to adulthood in VP/VLBW than term-born individuals, yet this difference in stability disappeared when individuals with severe cognitive impairment in adulthood were excluded. Cognitive function in adulthood could be fairly well estimated from age 6 years in term-born children and already from age 20 months in VP/VLBW children. IQ scores were highly stable in VP/VLBW individuals who had cognitive impairment in adulthood.. VP/VLBW children are known to be at risk for neurodevelopmental problems, including cognitive impairment and higher risk of lower educational qualifications in young adulthood compared with ...
Type 2 diabetes mellitus (DM2) is associated with moderate cognitive impairment in verbal memory, mental flexibility, and information processing speed, while other cognitive functions remain relatively unaffected.1 Moreover, epidemiological studies have shown that DM2 patients have a twofold increased risk of developing either vascular dementia or Alzheimers disease.1,2 In the present study we examined whether mild cognitive impairment (MCI) and cognitive impairment, no dementia (CIND)-two concepts that are used to describe cognitive impairment in the transitional state between normal aging and early dementia-can be applied to the cognitive impairments encountered in a population based sample of DM2 patients. Recently, these concepts have attracted considerable attention, as individuals who meet the criteria for either MCI or CIND are known to have a substantially increased risk of developing dementia.3,4 MCI is defined as a memory deficit without impairments in other cognitive domains.3 ...
The incidence of severe forms of HIV-associated neuorcognitive disorders, or HAND, has declined significantly with the availability of combination antiretroviral drug therapy over the last 20 years.. But the prevalence of the milder form has remained stable and even slightly increased, affecting 50 to 60 per cent of people living with HIV and AIDS.. Screening tools have not been updated to reflect this change, said Dr. Sean B. Rourke, a neuropsychologist who heads the Neurobehavioural Research Unit at St. Michaels. We are still trying to use or adapt the older dementia screening tools to catch the milder form of HAND.. Dr. Rourke said that having effective screening tests to identify and differentiate the two different forms of HAND is important for treatment decision-making. The current standards of practice requires a detailed neuropsychological examination, which is time-consuming and not readily accessible.. Identifying that patients have a mild form of this condition is critical, ...
Given the aging population and the corresponding increase in the incidence of AD, information on the prognosis of AD will help practitioners and unpaid caregivers to better meet the needs of patients with AD.. This well designed, prospective study by Larson et al provides estimates of survival after initial diagnosis of AD. Estimated survival rates were longer than those reported by the Canadian Study of Health and Aging (3.2 y for men and 3.4 y for women).1 This difference may be attributed to the older sample in the Canadian Study of Health and Aging.. Length of survival after onset of AD may be quite different from length of survival after initial diagnosis. Identifying the precise onset of AD may be difficult because of the insidious nature of the disease, unpaid caregivers lack of awareness of changes in cognition and functional abilities, and the patients ability to compensate for impairments. Although diagnosis at the onset of disease may not alter the natural course of AD, it could ...
This page includes the following topics and synonyms: Mini-Mental State Exam, Mini-Mental Status Exam, Folstein Mini Mental Status Exam, Folstein MMSE, MMSE.
Studies have investigated the potential protective effects that diet may have on late-life depression incidence. This disorder can, however, affect the persons food intake, widely known as the reverse causality hypothesis of depression. To test this hypothesis, we compared mean nutrient intakes from three 24-h recalls during the year depression was detected (Geriatric Depression Scale ≥11 or antidepressant medication) with intakes from 1 year earlier among community-dwelling older adults (67-83 years) followed up annually in the 4-year Québec Longitudinal Study on Nutrition and Aging, who were free of depression and cognitive impairment at baseline. Participants (n 158, 64·4 % female) who became depressed and had data available for all follow-up years were matched by age group and sex with non-depressed participants. General linear mixed models were adjusted for percentage changes in physical activity, functional autonomy and stressful life events reported at the time of positive screening. ...
TY - JOUR. T1 - Retinal signs and 20-year cognitive decline in the Atherosclerosis Risk in Communities Study. AU - Deal, Jennifer A. AU - Richey Sharrett, A.. AU - Rawlings, Andreea M.. AU - Gottesman, Rebecca F. AU - Bandeen Roche, Karen J. AU - Albert, Marilyn. AU - Knopman, David. AU - Selvin, Elizabeth. AU - Wasserman, Bruce A. AU - Klein, Barbara. AU - Klein, Ronald. PY - 2018/3/27. Y1 - 2018/3/27. N2 - Objective To test the hypothesis that retinal vascular signs are associated with greater cognitive decline over 20 years in 12,317 men and women 50 to 73 years of age at baseline. Methods A composite cognitive score was created with 3 neuropsychological tests measured at 3 time points (1990-1992 to 2011-2013). Retinal signs were measured with fundus photography (1993-1995). Differences in cognitive change by retinal signs status were estimated with linear mixed models. Cognitive scores were imputed for living participants with incomplete cognitive testing. Results In multivariable-adjusted ...
Cross-sectional studies have indicated potential for positron emission tomography (PET) in imaging tau pathology in Alzheimers disease (AD); however, its prognostic utility remains unproven. In a longitudinal, multi-modal, prognostic study of cognitive decline, 20 patients with a clinical biomarker-based diagnosis in the AD spectrum (mild cognitive impairment or dementia and a positive amyloid-beta PET scan) were recruited from the Cognitive Clinic at Karolinska University Hospital. The participants underwent baseline neuropsychological assessment, PET imaging with [18F]THK5317, [11C]PIB and [18F]FDG, magnetic resonance imaging, and in a subgroup cerebrospinal fluid (CSF) sampling, with clinical follow-up after a median 48 months (interquartile range = 32:56). In total, 11 patients declined cognitively over time, while 9 remained cognitively stable. The accuracy of baseline [18F]THK5317 binding in temporal areas was excellent at predicting future cognitive decline (area under the receiver operating
Although the Seattle Longitudinal Study was designed to focus on cognitive changes in normal community-dwelling populations, it is inevitable that a prospective study of aging will eventually include in its successive follow-up cycles individuals who are beginning to show cognitive impairment and eventually may develop full-blown symptoms of dementia. This chapter reports some initial findings on the apolipoprotein E genetic marker of dementia as it relates to cognitive decline. Studies involving the neuropsychological assessment of a community-dwelling sample of older adults who have not previously been identified as suffering from cognitive impairment are described, along with the extension analyses that link the clinical measures with the psychometric battery for the study of normal aging. The chapter ends by analyzing studies that obtain postdicted estimates of earlier performance on the neuropsychological measures and speak to the possibility of early detection of risk for cognitive ...
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Results:. The mean age of the patients was 80 years; 68% of patients were women. Patients with six or more depressive symptoms had greater comorbid illness, functional impairment, and cognitive impairment at admission than patients with fewer depressive symptoms. Three-year mortality was higher in patients with six or more depressive symptoms (56% compared with 40%; hazard ratio, 1.56 [95% CI, 1.22 to 2.00]; P , 0.001). After adjustment for age, acute illness severity, comorbid illness, functional impairment, and cognitive impairment at the time of admission, patients with six or more depressive symptoms continued to have a higher mortality rate during the 3 years after admission (hazard ratio, 1.34 [CI, 1.03 to 1.73]). Although depressive symptoms contributed less to the mortality rate than did the total burden of comorbid medical illnesses, the excess mortality rate associated with depressive symptoms was greater than that conferred by one additional comorbid medical condition. ...
The classification of neurodegenerative disorders is based on the major component of the protein aggregates in the brain. The most common altered proteins associated with neurodegeneration are Hyperphosphorylated tau (HPt), beta amyloid (Aβ), alpha-synclein (αS) and transactive response DNA binding protein 43 (TDP43). In this study we assessed the incidence and the neuroanatomical distribution of proteins associated with neurodegeneration in the brain tissue of cognitively unimpaired subjects.. We demonstrated the early involvement of the Locus Coeruleus (LC) with HPt pathology in cognitively unimpaired mid aged subjects, a finding which supports the notion that LC is an initiation site of HPt pathology. This may suggest that development of clinical assessment techniques and radiological investigations reflecting early LC alterations may help in identifying subjects with early stages of neurodegeneration.. Furthermore, we studied a large cohort of cognitively unimpaired subjects with age at ...
welcome to the forum! i agree that one of the most frustrating parts of this dd is the problem with cognitive functions. i am currently working towards my bachelors in accounting and have definitely seen a decline in my ability to remember information. i have had to fall back on notes, notes, notes! i have notes in a couple of different places regarding when everything is due-in my planner, on my dry erase board, sticky notes on my computer-and that seems to really have helped me get things done on time. with regards to remembering important information, ive started relating information i need to know to other things..little tips or jingles or small poems or whatever that contains the information i need to remember and that has really helped, too. also, i take all of my classes online (which is very helpful!) and NEVER do homework or take a test if im in a lot of pain or overly tired or hungry. if youre taking in person classes then you obviously dont have the freedom of flexibility that ...
Retention of certain metabolites in the blood may contribute to cognitive impairment in patients with kidney failure, revealed a new study.
The vast majority of people in the United States have I.Q.s between 80 and 120, with an I.Q. of 100 considered average. To be diagnosed as having mental retardation, a person must have an I.Q. below 70-75, i.e. significantly below average. If a person scores below 70 on a properly administered and scored I.Q.. ...
Cognitive dysfunction can make a person feel hopeless, and they may turn to unfortunate sources in an effort to regain some control over their mental state. Commonly abused substances include alcohol, illegal narcotics and prescription drugs. Stimulants are a commonly abused drug for those who are dealing with cognitive issues that impair the sharpness of their mental processes. It is also possible to become addicted to legitimately prescribed medication that was initially aimed at treating a cognitive disorder. Individuals with cognitive impairment may become dependent on their medications and suffer withdrawal if they attempt to get off them without proper medical supervision.. If you or a loved one is addicted to medication for a cognitive disorder, help is available. Call our 24/7 hotline at 1-888-997-3147 for information on how you can get free of your addiction while managing the symptoms of your cognitive disorder.. ...
Multivariable repeated measures regression analysis identified three independent predictors of NPZ-3 worsening during follow-up ranging from 2 to 9 years (median 6): More years since entering the parent study (and thus more years on ART) and a time-varying CD4 count above 350 (versus below) protected against neurocognitive decline. Compared with a nadir CD4 count below 51, a nadir of 51 to 200 or above 200 tended to protect against decline, but those associations fell short of statistical significance. Among comorbidity risk factors, only a history of stroke independently raised the odds of declining NPZ-3 score. In a nonsignificant association, injection drug use tended to boost odds of worsening neurocognitive function ...
Results A total of 12,336 participants (baseline age 56.8 [5.7], 21% black, 56% women) were included. After adjusting for demographic variables, vascular risk factors, and comorbidities, each standard deviation (SD) increase in midlife inflammation composite score was associated with an additional 20-year decline of −0.035 SD (95% confidence interval: −0.062 to −0.007) on the cognitive composite score. We found a similar association between each SD increase in midlife CRP level and additional 20-year cognitive decline (−0.038 SD, 95% confidence interval: −0.057 to −0.019). Participants with a midlife inflammation composite score in the top quartile had a 7.8% steeper cognitive decline, compared to participants in the lowest quartile; CRP in the top quartile was associated with an 11.6% steeper cognitive decline. In cognitive domain-specific analyses, elevated midlife inflammatory markers were most consistently associated with declines in memory. Results were similar after adjusting ...
Effects of momentum-based dumbbell training on cognitive function in older adults with mild cognitive impairment: a pilot randomized controlled trial Jiaojiao Lü,1 Mingyun Sun,2,3 Leichao Liang,1 Yi Feng,1 Xiaoyu Pan,1 Yu Liu1 1Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, 2Institue of Physical Education, Anqing Normal University, Anqing, 3Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, People’s Republic of China Purpose: The purpose of this study was to explore the effects of an innovative momentum-based dumbbell-training intervention on cognitive function in older adults with mild cognitive impairment (MCI).Subjects and methods: A total of 45 community-dwelling older adults with MCI were randomly assigned to either a dumbbell-training group (DTG; n=22) or a control group (CG; n=23). Participants in the DTG participated in exercise sessions three times weekly for 12 weeks. The primary
TY - JOUR. T1 - Cognitive impairment is a negative short-term and long-term prognostic factor in elderly patients with hip fracture. AU - Benedetti, M. G.. AU - Ginex, V.. AU - Mariani, E.. AU - Zati, A.. AU - Cotti, A.. AU - Pignotti, E.. AU - Clerici, F.. PY - 2015/12/1. Y1 - 2015/12/1. N2 - Background. Subjects with severe cognitive impairment (CI) have a high-risk of hip fractures with increased rate of adverse postoperative functional outcomes and mortality. Aim. To evaluate the impact of different degrees of CI on functional recovery and mortality after hip fracture. Design. Prospective observational study. Setting. Two orthopedic surgery units. Population. Two hundred twenty-eight consecutive patients after a hip surgery. Methods. Patients were assessed at baseline through the Short Portable Mental Status Questionnaire (SPMSQ), an instrument that allows to categorize subjects as follows: cognitively intact (SPMSQ≥8) or with mild (SPMSQ=6-7), moderate (SPMSQ=3-5) and severe CI ...
March 18, 2014 - Brain imaging using nuclear imaging radiotracers can detect early evidence of Alzheimers disease that may predict future cognitive decline among adults with mild or no cognitive impairment. This is according to a 36-month follow-up study led by Duke Medicine.. The national, multicenter study confirms earlier findings suggesting that identifying silent beta-amyloid plaque build-up in the brain could help guide care and treatment decisions for patients at risk for Alzheimers. The findings appeared online March 11, 2014, in Molecular Psychiatry, a Nature Publishing Group journal.. Our research found that healthy adults and those with mild memory loss who have a positive scan for these plaques have a much faster rate of decline on memory, language and reasoning over three years, said lead author P. Murali Doraiswamy, M.D., professor of psychiatry and director of the neurocognitive disorders program at Duke.. Alzheimers disease - which currently has no cure - afflicts an ...
Selkoe cautions that a commercial test for routine clinical care likely remains several years away. But for clinical trials that seek to evaluate preventive treatments for AD, such as the large-scale clinical trials led by co-author Reisa Sperling, MD, MMSc, director of the Center for Alzheimer Research and Treatment at the Brigham and Womens Hospital, NT1 levels could be measured before a participant enrolls in a trial, and potentially also as a longitudinal measure to assess treatment response. The test ultimately represents a far less costly and less invasive alternative to imaging and lumbar punctures ...
A study published in the journal Nature Neuroscience, from Nature publishing group, describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinsons disease.
Butterworth, B. (1992). "Disorders of phonological encoding". Cognition. 42 (1-3): 261-286. CiteSeerX 10.1.1.572.1032. doi: ... Cognition. 93 (2): 99-125. CiteSeerX 10.1.1.123.8504. doi:10.1016/j.cognition.2003.11.004. PMID 15147931. S2CID 14205159. PDF ... Over 18,000 people took part-the largest number ever to take part in a mathematical cognition experiment. He announced his ... Butterworth, B. (1994). "Disorders of Sentence Production". Philosophical Transactions of the Royal Society B: Biological ...
"Anosognosia/anosognosic - Eating Disorders Glossary". glossary.feast-ed.org. Retrieved 2015-06-23. Pia, Lorenzo; Tamietto, ... Cognition. 15 (1-3): 111-44. doi:10.1016/0010-0277(83)90036-7. PMID 6686505. S2CID 29284758. " ... This phenomenon of double dissociation can be an indicator of domain-specific disorders of awareness modules, meaning that in ... Anosognosia may occur as part of receptive aphasia, a language disorder that causes poor comprehension of speech and the ...
Lists of language disorders "Definition of paragrammatism". Oxford Dictionaries (British & World English). CS1 maint: ... discouraged parameter (link) Butterworth, Brian; Howard, David (1987). "Paragrammatisms". Cognition. 26 (1): 1-37. doi:10.1016/ ... Since Kleist introduced the term in 1916, paragrammatism has denoted a disordered mode of expression that is characterized by ...
Brain and Cognition. 25 (1): 1-23. doi:10.1006/brcg.1994.1019. PMID 8043261. S2CID 30261660. De Renzi, E. (2000). "Disorder of ... De Renzi E (2000). "Disorder of Visual Recognition". Seminars in Neurology. 20 (4): 479-485. doi:10.1055/s-2000-13181. PMID ... Buchtel, H.A.; Stewart, J.D. (1989). "Auditory Agnosia: Apperceptive or Associative Disorder?". Brain and Language. 37 (1): 12- ... Brain and Cognition. 33 (3): 306-342. doi:10.1006/brcg.1997.0876. PMID 9126398. S2CID 11582998. Duffy CJ (January 1999). " ...
"Executive functions in children with autism spectrum disorders". Brain and Cognition. 71 (3): 362-8. doi:10.1016/j.bandc. ... gene in personality and related psychopathological disorders". CNS & Neurological Disorders Drug Targets. 11 (3): 236-50. doi: ... Risk of liver toxicity and related digestive disorders restricts the use of tolcapone. Dopamine Schizophrenia O- ... Tunbridge EM, Harrison PJ, Weinberger DR (July 2006). "Catechol-O-methyltransferase, cognition, and psychosis: Val158Met and ...
Fregoli delusion Gestalt Psychology Hollow-Face illusion Nonverbal learning disorder Pareidolia Prosopagnosia Social cognition ... Autism spectrum disorder (ASD) is a comprehensive neural developmental disorder that produces many deficits including social, ... Cognition. 150: 163-169. doi:10.1016/j.cognition.2016.02.010. PMID 26896901. S2CID 1096220. Charles A. Nelson (March-June 2001 ... Mutation from the wild type allele at these loci has also been found to result in other disorders in which social and facial ...
... being a common feature of anxiety disorders, particularly generalized anxiety disorder. Thought suppression, an example of ... Walker, Matthew P. (March 2009). "The Role of Sleep in Cognition and Emotion" (PDF). Annals of the New York Academy of Sciences ... It has also been implicated in a host of disorders including major depression. Worry, an example of attentional deployment, ... Borkovec, T. D.; Inz, J. (1990). "The nature of worry in generalized anxiety disorder: A predominance of thought activity". ...
Taleb, Nassem (2012-11-27). Antifragile: Things That Gain from Disorder. ISBN 978-1-4000-6782-4. Forsyth, D. K. (June 2008). " ... "Allocating time to future tasks: The effect of task segmentation on planning fallacy bias". Memory & Cognition. 36 (4): 791-798 ...
Brain, Behaviour and Cognition Series. Hove, UK Hillsdale, USA: Lawrence Erlbaum Associates, Inc. ISBN 9780863773037. David, ... in schizophrenia and other disorders. Professor David is a Fellow of the Royal College of Physicians, the Royal College of ... Anthony S.; Ron, Maria A. (1999). Disorders of brain and mind: volume 1. Cambridge: Cambridge University Press. ISBN ... awareness of illness in schizophrenia and related disorders (2nd ed.). Oxford: Oxford University Press. ISBN 9781417599912. ...
Cognition, 116(1), 130-135. {IF=3.481} Grüter, T., & Carbon, C. C. (2010). Escaping attention. Some cognitive disorders can be ...
... and language development in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43(2), 301- ... Cognition, 60(3), 235-268. Brooks, P.J., & Ploog, B. (2013). Attention to emotional tone of voice in speech perception in ... Research in Autism Spectrum Disorders, 7(7), 845-857. Brooks, P.J., Seiger-Gardner, L. & Sailor, K. (2012). Contrasting effects ... Cognition. 60 (3): 235-268. doi:10.1016/0010-0277(96)00712-3. PMID 8870514. S2CID 12961472.CS1 maint: multiple names: authors ...
Imperfect Cognitions. Diagnostic and statistical manual of mental disorders: DSM-5. American Psychiatric Association. 2013. " ... This one states that some of those persons who are predisposed might suffer the onset of delusional disorder in those moments ... One is the genetic or biological theory, which states that close relatives of people with delusional disorder are at increased ... Higher levels of dopamine qualify as a symptom of disorders of brain function. That they are needed to sustain certain ...
This gives rise to PTSD symptoms such as trauma-related cognitions, appraisals, and emotions. The SAM system captures vivid ... Dual representation theory (DRT) is a psychological theory of post-traumatic stress disorder (PTSD) developed by Charles Brewin ... Rubin, David C.; Boals, Adriel; Berntsen, Dorthe (2008). "Memory in posttraumatic stress disorder: Properties of voluntary and ... Brewin, Chris R.; Dalgleish, Tim; Joseph, Stephen (1996). "A dual representation theory of posttraumatic stress disorder". ...
Aspen, Vandana; Darcy, Alison M.; Lock, James (2013-08-01). "A review of attention biases in women with eating disorders". ... Cognition and Emotion. 27 (5): 820-838. doi:10.1080/02699931.2012.749777. ISSN 0269-9931. PMC 3610839. PMID 23228135. Earley, ... Darcy continued to research eating disorders, with a particular focus on anorexia nervosa. She recognised that very few ... and worked with a charity to support people with eating disorders. At the time there was very little online support for people ...
Myrna G Crago MB (1991). "Familial aggregation of a developmental language disorder". Cognition. 39 (1): 1-50. doi:10.1016/0010 ... A forkhead-domain gene is mutated in a severe speech and language disorder. Gopnik's son Adam is a well-known novelist and ... Simon Fisher and colleagues at Oxford University identified a mutation in the FOXP2 gene as a cause of the KE family's disorder ...
Cognition, 108(2) 303-319. Smith, A. D., Hood, B. M, & Hector, K. (2006) Eye remember you two: gaze direction modulates face ... Autism spectrum disorders (ASDs) which include autism and Asperger syndrome are characterized by social interaction and ... Cognition, 102(3) 396-404. Senju, A., Csibra, G., & Johnson, M. H. (2008) Understanding the referential nature of looking: ... The eye-contact effect is a psychological phenomenon in human selective attention and cognition. It is the effect that the ...
"Brain oscillations in cognition and disorders". Neuronal Oscillations. Retrieved 29 June 2020. Ole Jensen publications indexed ... Jensen's research mainly focuses on the neuronal oscillatory dynamics supporting cognition in animals and humans. In particular ... Cognition and Behaviour. In 2016 he was appointed as professor in Translational Neuroscience at University of Birmingham, ...
Patients with this form of aphasia may present with a contiguity disorder in which they have difficulty combining linguistic ... Shigaki CL, Frey SH, Barrett AM (2014). "Rehabilitation of poststroke cognition". Medscape. 34 (5): 496-503. Savage, Meghan; ... Transcortical sensory aphasia Brookshire, R. H. (2007). Introduction to Neurogenic Communication Disorders. St. Louis, MO: ... or progressive neurological disorders. TMoA is diagnosed by the referring physician and speech-language pathologist (SLP). The ...
Deficits can occur in people with autism spectrum disorders, genetic-based eating disorders, schizophrenia, attention deficit ... While many theories make claims about its role in the development of human language and social cognition few of them specify in ... people with nonverbal learning disorder, people with attention deficit hyperactivity disorder, persons under the influence of ... In W. F. Overton (Ed.), Biology, cognition and methods across the life-span. Volume 1 of the Handbook of life-span development ...
Dissociations between language and cognition. Journal of Autism and Developmental Disorders, vol. 11, 1, 15-30. Curtiss, S. ... "Dissociations between language and cognition: Cases and implications." Journal of autism and developmental disorders 11.1 (1981 ... Brain and Cognition, 32, 45-66. Curtiss, S. 1978. A New "Wild Child"? [Review of the book The Wild Boy of Burundi: A Study of ... Brain and Cognition, vol. 43, 135-205. Fromkin, V., Krashen, S., Curtiss, S., Rigler, D. and Rigler, M. 1974. The development ...
"An investigation of basic facial expression recognition in autism spectrum disorders". Cognition and Emotion. 22 (7): 1353-1380 ... Deficits in affective perception have also been linked with Autism (Autistic Spectrum Disorder). A number of studies have ... The Emerging Neuroscience of Autism Spectrum Disorders. 1380: 34-41. doi:10.1016/j.brainres.2010.11.031. ISSN 0006-8993. Poole ...
"Superior fluid intelligence in children with Asperger's disorder". Brain and Cognition. 66 (3): 306-310. doi:10.1016/j.bandc. ... A 2007 study provided evidence that individuals with Asperger syndrome, a high-functioning autism spectrum disorder, score ... Another 2007 study provided evidence that individuals with classic autism, a low-functioning autism spectrum disorder, score ...
Developmental Disorders of Language Learning and Cognition. Chichester, U.K.: Wiley-Blackwell, 2009. Snowling, Margaret J., and ... Dyslexia: Biology, Cognition, and Intervention. San Diego, Calif: Singular Pub. Group, 1997. Hulme, Charles, and Susie ... Also published in Spanish, Hulme, Charles, and R. Malatesha Joshi,co-editors Reading and Spelling: Development and Disorders. ...
Cognition and Emotion, 29(8), 1496-1504. DOI: 10.1080/02699931.2014.992394 Zuroff, D.C., Sadikaj, G., Kelly, A.C., & Leybman, M ... Self-criticism is often associated with major depressive disorder. Some theorists[who?] define self-criticism as a mark of a ... These three categories all deal with self-critical cognitions, and are measured by the Attitude Toward Self Scale, which Carver ... Clark, L.A., Watson, D., & Mineka, S. (1994). Temperament, personality, and the mood and anxiety disorders. Journal of Abnormal ...
Brain and Cognition, 34(2), 287-292. Haaland, K. Y., & Flaherty, D. (1984). The different types of limb apraxia errors made by ... Journal of Nervous and Mental Disorders. 126, 9-32. doi: 10.1097/00005053 Boyatzis, C. J., & Watson, M. W. (1993). Preschool ... Brain and Cognition, 3, 370-384. Pylyshyn, Z. W. (1978). When is attribution of beliefs justified? Behavioral and Brain ... Brain and Cognition, 25, 250-270. Martin, P., Tewesmeier, M., Albers, M., Schmid, G., & Scharfetter, C. (1994). Investigation ...
Developmental Disorders of Language Learning and Cognition. John Wiley & Sons. ISBN 978-0-631-20611-8. Rydelius PA (March 2000 ... DAMP is diagnosed on the basis of concomitant attention deficit/hyperactivity disorder and developmental coordination disorder ... this would be a hyperkinetic disorder combined with a developmental disorder of motor function.) About half of children with ... The new definition is as follows: ADHD as defined in DSM-IV; Developmental Coordination Disorder (DCD) as defined in DSM-IV; ...
"Empathic accuracy and cognition in schizotypal personality disorder". Psychiatry Research. 210 (1): 232-241. doi:10.1016/j. ... Proponents of the hypothesis also point towards genetic disorders with an elevated risk of one disorder and not the other, ... Causes of autism Conditions comorbid to autism spectrum disorders Multiple complex developmental disorder Russell-Smith, ... which is considered a more homogenous form of the disorder that hews closest to the hypothetical neurodevelopmental disorder ...
Upon realizing that patients with Autism Spectrum Disorder often have additional disorders (including intellectual disability, ... Oxytocin increases retention of social cognition in autism. Biological Psychiatry. 2007. King et al. Lack of efficacy of ... Network in 2013 to study multiple neurodevelopmental disorders (including Autism Spectrum Disorder) together. She is a ... Her research focuses on translating findings from basic research studies in the field of Autism Spectrum Disorder and related ...
Cserjési, R (Jun 2009). "Affect, cognition, awareness and behavior in eating disorders. Comparison between obesity and anorexia ... 1997). "Eating disorders and antecedent anxiety disorders: a controlled study". Acta Psychiatrica Scandinavica. 96 (2): 101-107 ... Costa, P. T.; McCrae, R. R. (1990). "Personality disorders and the five factor model of personality". Journal of Personality ... Corstorphine, E; Waller, G; Lawson, R; Ganis, C (Jan 2007). "Trauma and multi-impulsivity in the eating disorders". Eating ...
Bishop DV (March 2009). "Genes, cognition, and communication: insights from neurodevelopmental disorders". Annals of the New ... Lexical deficit disorder - the child has word finding problems and difficulty putting ideas into words. There is poor ... It is now generally accepted that SLI is a strongly genetic disorder. The best evidence comes from studies of twins. Two twins ... SLI is associated with a high rate of psychiatric disorder. For instance, Conti-Ramsden and Botting (2004) found that 64% of a ...
Cognition, discrimination, and learning[edit]. Computational modeling of higher cognitive functions has only recently[when?] ... Browne, A. (1997-01-01). Neural Network Perspectives on Cognition and Adaptive Robotics. CRC Press. ISBN 9780750304559.. ... The Computational Representational Understanding of Mind (CRUM) is another attempt at modeling human cognition through ... "Modeling language and cognition with deep unsupervised learning: a tutorial overview". Frontiers in Psychology. 4. doi:10.3389 ...
Substance-use disorder: A diagnostic term in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders ( ... Shettleworth, S. J. (2010). Cognition, Evolution and Behavior (2nd ed.). New York: Oxford.. .mw-parser-output cite.citation{ ... Sensitization may also contribute to psychological disorders such as post-traumatic stress disorder, panic anxiety and mood ... substance use disorder - a condition in which the use of substances leads to clinically and functionally significant impairment ...
... is able to detect consistent patterns of abnormalities in patients with subtle cognitive dysfunctions and psychiatric disorders ... Molecular cellular cognition. *Motor control. *Neurolinguistics. *Neuropsychology. *Sensory neuroscience. *Social cognitive ...
doi:10.1016/j.cognition.2007.11.002. PMID 18068696.. *^ Gallace A.; Tan H.Z.; Spence C. (2008). "Can tactile stimuli be ... However, people with simultanagnosia have no difficulty enumerating objects within the subitizing range.[23] The disorder is ... Patients with this disorder suffer from an inability to perceive visual scenes properly, being unable to localize objects in ...
Amso D.; Casey B.J. (2006). "Paper: Beyond what develops when: neuroimaging may inform how cognition changes with development ... and work on developmental disorders by Annette Karmiloff-Smith. ...
Acrodermatitis chronica atrophicans (ACA) is a chronic skin disorder observed primarily in Europe among the elderly.[39] ACA ... complex cognition, and emotional status. White matter disease may have a greater potential for recovery than gray matter ... where physician Alfred Buchwald described a man who had suffered for 16 years with a degenerative skin disorder now known as ... which has been misdiagnosed as schizophrenia or bipolar disorder. Panic attacks and anxiety can occur; also, delusional ...
In W. F. Overton (Ed.), Biology, cognition and methods across the life-span. Volume 1 of the Handbook of life-span development ... The aim is to explain the order and systematicity that exist beneath a surface of apparent disorder or "chaos". ... Brain and Cognition, 20, 24-50. *^ Demetriou, a., Shayer, & Spanoudis (in press). Inference, reconceptualization, insight, and ...
"National Organization for Rare Disorders. 2017. Retrieved 5 November 2016.. *^ Garland, Theodore; Morgan, Martin T.; Swallow, ... One of these genes, CACNA1C, has been found to influence cognition. It has been associated with autism, as well as linked in ... "Pleiotropy of psychiatric disorders will reinvent DSM". www.mdedge.com. Retrieved 2016-11-13.. ... Marfan syndrome (MFS) is an autosomal dominant disorder which affects 1 in 5-10,000 people.[36] MFS arises from a mutation in ...
Definitions and Classification of Tic Disorders.. Retrieved 19 August 2006.. *^ Zinner, S.H. (2000). "Tourette disorder". ... Oxford Handbook of Human Action (Volume 2 of Social Cognition and Social Neuroscience ed.). Oxford University Press. pp. 487 ff ... Oxford Handbook of Human Action (Volume 2 of Social Cognition and Social Neuroscience ed.). Oxford University Press. pp. 487 ff ... Ebert, J.P.; Wegner, D.M. (2011). "March 1). Mistaking randomness for free will". Consciousness and Cognition. 20 (3): 965-71. ...
"Long-term effects of chronic khat use: impaired inhibitory control". Frontiers in cognition. 12 January 2011. doi:10.3389/fpsyg ... health suggested that there was a need for better research on khat-chewing and its possible link with psychiatric disorders; it ...
Panic disorder. Moclobemide is useful in the treatment and management of panic disorder.[43] Panic disorder is mentioned as an ... that cognition is improved in the elderly, and moclobemide has low potential for food and drug interactions opened up a new ... Tiller JW, Bouwer C, Behnke K (October 1997). "Moclobemide for anxiety disorders: a focus on moclobemide for panic disorder". ... Bipolar disorder (although it seems less likely than imipramine to cause a manic switch[34]) ...
Medical disordersEdit. AutismEdit. Music has played an important role in the research of dealing with autism, mainly in ... By working with a certified music therapist, marines undergo sessions re-instituting concepts of cognition, memory attention, ... such as mood/anxiety disorders and eating disorders, or inappropriate behaviors, including suicide attempts, withdrawal from ... Crowe, Barbara J. (2007). Music Therapy for Children, Adolescents and Adults with Mental Disorders. Silver Spring, MD: American ...
"From disorder to order in marching locusts" (PDF). Science. 312 (5778): 1402-1406. Bibcode:2006Sci...312.1402B. doi:10.1126/ ... Cognition. *Animal communication. *Animal consciousness. *Animal language. *Cognitive bias in animals. *Cognitive ethology ...
"Memory & Cognition. 10 (4): 389-395. doi:10.3758/BF03202431. PMID 7132716.. *^ a b Durgin, F (2000). "The Reverse Stroop Effect ... attention-deficit hyperactivity disorder, or a variety of mental disorders such as schizophrenia, addictions, and depression.[ ... Lansbergen MM, Kenemans JL, van Engeland H (March 2007). "Stroop interference and attention-deficit/hyperactivity disorder: a ... An increased interference effect is found in disorders such as brain damage, dementias and other neurodegenerative diseases, ...
"MedlinePlus: Movement Disorders".. *↑ Baizabal-Carvallo, JF; Jankovic J. (2012-07-18). "Movement disorders in autoimmune ... diseases". Movement disorders : official journal of the Movement Disorder Society. 27 (8): 935-46. doi:10.1002/mds.25011. PMID ... Fahn, Stanley; Jankovic, Joseph; Hallett, Mark (2011-08-09). Principles and Practice of Movement Disorders. Elsevier Health ... Singer, Harvey S.; Mink, Jonathan; Gilbert, Donald L.; Jankovic, Joseph (2015-10-27). Movement Disorders in Childhood. Academic ...
... bipolar disorder, and major depression. Swartz Center for the Neural Mechanisms of Cognition studies cognition in the normal ... Watson initiated a major push to scale-up CSHL research on the brain and psychiatric disorders, beginning in the late 1980s. In ... brain as a baseline for understanding dysfunction in psychiatric and neurodegenerative disorders. Other research foci: autism ...
Depressive disorders and the menopause transition. Maturitas. 2012, 71 (2): 120-30. PMID 22196311. doi:10.1016/j.maturitas. ... Clement, YN; Onakpoya, I; Hung, SK; Ernst, E. Effects of herbal and dietary supplements on cognition in menopause: a systematic ... Hurst, Bradley S. Disorders of menstruation. Chichester, West Sussex: Wiley-Blackwell. 2011 [2017-07-17]. ISBN 9781444391817. ( ... "induces bone formation and increases bone mineral density reducing the risk for osteoporosis and other bone disorders" pursuant ...
Main article: Music-specific disorders. Focal hand dystonia[edit]. Focal hand dystonia is a task-related movement disorder ... doi:10.1016/j.cognition.2003.10.011. PMID 15037127.. *^ Scott, S. K. & Johnsrude, I. S. "The neuroanatomical and functional ... Peretz, Isabelle (2008). "Musical Disorders: From Behavior to Genes". Current Directions in Psychological Science. 17 (5): 329- ... Chen, R; Hallett, M (1998). "Focal dystonia and repetitive motion disorders". Clinical Orthopaedics and Related Research (351 ...
Consciousness and Cognition. *Consciousness Explained. *How the Self Controls Its Brain. *Journal of Consciousness Studies ...
Lamellar corpuscles, or Pacinian corpuscles, are pressure receptors located in the skin and also in various internal organs. Each is connected to a sensory neuron. Because of its relatively large size, a single lamellar corpuscle can be isolated and its properties studied. Mechanical pressure of varying strength and frequency can be applied to the corpuscle by stylus, and the resulting electrical activity detected by electrodes attached to the preparation. Deforming the corpuscle creates a generator potential in the sensory neuron arising within it. This is a graded response: the greater the deformation, the greater the generator potential. If the generator potential reaches threshold, a volley of action potentials (nerve impulses) are triggered at the first node of Ranvier of the sensory neuron. Once threshold is reached, the magnitude of the stimulus is encoded in the frequency of impulses generated in the neuron. So the more massive or rapid the deformation of a single corpuscle, the higher ...
"Journal of Experimental Psychology: Learning, Memory, and Cognition. 35 (1): 196-204. doi:10.1037/a0014104. PMC 2750806. PMID ... Mental disorders such as ADHD are linked to mind-wandering. Seli et. al. (2015) found that spontaneous mind-wandering, the ... "Journal of Experimental Psychology: Learning, Memory, and Cognition. 38 (3): 529-549. doi:10.1037/a0025896. PMC 3395723. PMID ... In many disorders it is the regulation of the overall amount of mind-wandering that is disturbed, leading to increased ...
Schizophrenia occurs along with obsessive-compulsive disorder (OCD), a disorder in which a person becomes obsessed with certain ... Kircher, Tilo and Renate Thienel (2006). "Functional brain imaging of symptoms and cognition in schizophrenia". The Boundaries ... Berrios G.E.; Porter, Roy (1995). A history of clinical psychiatry: the origin and history of psychiatric disorders. London: ... People with this disorder often do not behave the way most people do towards others. They also may not know what is real (this ...
As a clinician, he and his collaborators have studied and treated disorders of behaviour and cognition, and movement disorders ... Parvizi J, Damasio AR (2001). "Consciousness and the brainstem". Cognition. 79 (1-2): 135-160. doi:10.1016/S0010-0277(00)00127- ... Damasio might believe that emotions play a critical role in high-level cognition-an idea counter to dominant 20th-century views ... Cognition. 33 (1-2): 25-62. CiteSeerX 10.1.1.308.6140. doi:10.1016/0010-0277(89)90005-X. PMID 2691184. S2CID 34115898.. ...
... disordersEdit. Main article: Anxiety disorder. Anxiety disorders are a group of mental disorders characterized by ... cognitions, and situational factors, intergroup contact may be stressful and lead to feelings of anxiety. This apprehension or ... Anxiety disorders often occur with other mental disorders, particularly major depressive disorder, personality disorder, and ... They often occur with other mental disorders, particularly bipolar disorder, eating disorders, major depressive disorder, or ...
Cognition. 104 (2): 231-253. doi:10.1016/j.cognition.2006.05.013. Gillner S, Mallot H (2000). "The role of global and local ... Topographical disorientation is a cognitive disorder that results in the individual being unable to orient his or herself in ... DTD is a relatively new disorder and can occur in varying degrees of severity. Topographical Disorientation in Mild Cognitive ... Lipska, B.K.; Weinberger, D.R. (2000). "To model a psychiatric disorder in animals: Schizophrenia as a reality test". ...
Diseases and disorders of the brain, including alogia, aphasias, dysarthria, dystonia and speech processing disorders, where ... have maintained is the use in thinking of silent speech in an interior monologue to vivify and organize cognition, sometimes in ... Diseases and disorders of the lungs or the vocal cords, including paralysis, respiratory infections (bronchitis), vocal fold ... In addition to dysphasia, anomia and auditory processing disorder can impede the quality of auditory perception, and therefore ...
Imagination, Cognition and Personality, Vol. 26, No. 3, 2007, pp191-211. Cocude, M., and Denis, M., Measuring the temporal ... Holmes, E. A., and Mathews, A., Mental imagery in emotion and emotional disorders. Clinical Psychology Review, Vol. 30, No. 3, ... Holmes, E. A., and Mathews, A., Mental imagery in emotion and emotional disorders. Clinical Psychology Review, Vol. 30, No. 3, ... Is guided self-help as effective as face-to-face psychotherapy for depression and anxiety disorders? A systematic review and ...
The disorder causes muscle weakness, atrophy, and muscle spasms throughout the body due to the degeneration of the upper motor ... this may be due in part to deficits in social cognition.[38] About half the people who have ALS experience emotional lability, ... Gordon PH, Miller RG, Moore DH (September 2004). "ALSFRS-R". Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 5 ... "Therapeutic Advances in Neurological Disorders. 11: 1756285617734734. doi:10.1177/1756285617734734. PMC 5784546. PMID 29399045. ...
From "... A Review... " (2012): SPS is "unrelated to Sensory Processing Disorder". *From "The Clinical Implications of Jung's ... and disorders[11][15] with which high SPS can be confused;[16] overcoming the social unacceptability that can cause low self- ... sensory processing disorder,[15] and autism[10]), and further, that SPS may be a basic variable that may underlie multiple ... They assert that the trait is not a disorder but an innate survival strategy that has both advantages and disadvantages.[10][11 ...
The scientific study of the biological mechanisms that underlie the disorders and diseases of the nervous system. ... Cognitive neuroscience is the study of the biological mechanisms underlying cognition. Computational neuroscience Computational ... Neurogastronomy is the study of flavor and how it affects sensation, cognition, and memory.[32] ... Psychiatry focuses on affective, behavioral, cognitive, and perceptual disorders. Anesthesiology focuses on perception of pain ...
... the glutamate NMDA receptor antagonist memantine may improve the cognitive deficits of bipolar disorder. ... Cite this: Memantine May Improve Cognition in Bipolar Disorder - Medscape - Jun 19, 2013. ... Fifty-five percent of the patients had type I bipolar disorder, and 45% had bipolar II disorder. All had reported subjective ... "So we saw that people did better on tests of cognition, and also saw biological changes occurring at the same time in the brain ...
Cognition and daytime functioning in sleep-related breathing disorders.. Jackson ML1, Howard ME, Barnes M. ... Sleep-related breathing disorders encompass a range of disorders in which abnormal ventilation occurs during sleep as a result ... Moderate to severe cases of the disorder are at a higher risk of having a motor vehicle accident, and may also have ... Chronic excessive sleepiness during the day is a common symptom of sleep-related breathing disorders, which is assessed in ...
Lethargy with lower body temperature, cognition? Ephedra I recently barely finished a very low dose, 6 month course of ... You will kill yourself a lot quicker than the disorder will... Please get back to me ASAP...my husband was just diagnosed and ... You will kill yourself a lot quicker than the disorder will... Please get back to me ASAP...my husband was just diagnosed and ... I have some excellent research and information on HHC and as well as other iron loading disorders, and links to sites where you ...
In several neurodevelopmental disorders, cognitive difficulty is reported as ... in the brain that regulates normal cognitive abilities but is also implicated with a range of neurodevelopmental disorders, ... Normal Cognition, Neurodevelopmental Disorders Share the Same Brain Space. By Traci Pedersen. ~ 1 min read ... Pedersen, T. (2016). Normal Cognition, Neurodevelopmental Disorders Share the Same Brain Space. Psych Central. Retrieved on ...
Modern diagnostic schemes differentiate between Major Depressive Disorder and Bipolar Disorders, but there is much overlap ... Cognitive impairment in patients with mood disorders is being recognised as a significant factor that can have an impact on ... The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) includes cognitive symptoms as one of ... Indeed, patients may think they have attention-deficit disorder or, if older, Alzheimers disease. Such cognitive symptoms may ...
Developmental Disorders of Language Learning and Cognition. Charles Hulme, Margaret J. Snowling ... This important new text is a comprehensive survey of current thinking and research on a wide range of developmental disorders. ... He has conducted research on a wide range of developmental disorders. His current research focuses particularly on ... A comprehensive survey of current thinking and research on a wide range of developmental disorders. ...
Cognition and Language Disorders Projekt group leader. Per Östberg. Neurological diseases often affect brain regions that are ... Syntactic complexity and cognition. *Central auditory dysfunction in primary hearing assessment (with Esma Idrizbegovic, ... Projects that we participate in focus on aphasia and the broader category of cognitive-communication disorders. ...
It is widely accepted that patients with schizophrenia and bipolar disorders have deficits in social cognition; however, ... These results suggest that social cognition deficits could be related to a general impairment in the capacity to implicitly ... Findings This study evaluates the performance of patients with schizophrenia and bipolar disorders on social cognition tasks ( ... The results showed that both patient groups exhibited deficits in social cognition tasks with greater context sensitivity and ...
Recent research suggests that social cognitive deficits in both disorders may arise from dysfunctions in the neural systems t … ... Schizophrenia and autism both feature significant impairments in social cognition and social functioning, but the specificity ... Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders Schizophr Res. 2008 Feb;99(1-3):164- ... social cognitive deficits in both disorders may arise from dysfunctions in the neural systems that underlie social cognition. ...
Bipolar Disorder. Psychotic Disorders. Mental Disorders. Pathologic Processes. Bipolar and Related Disorders. Schizophrenia ... Treatment to Enhance Cognition in Bipolar Disorder (TREC-BD). The safety and scientific validity of this study is the ... Treatment to Enhance Cognition in Bipolar Disorder (TREC-BD): Efficacy of a Randomized Controlled Trial of Cognitive ... 13 programs targeting cognition in 4 separate domains: Auditory processing, visual processing, social cognition, and executive ...
Glutamate and Disorders of Cognition and Motivation. Edited by Edited by Bita Moghaddam (Yale University School of Medicine, ... About 10-15 years ago, a few scientists began studying the possible role of glutamate in these disorders, led by awareness of ... Although glutamate-mediated neurotransmission has long been implicated in neurodegenerative disorders, the major focus of ... research on cognitive, affective, and addictive disorders has been on monoamine (dopamine, serotonin, norephinephrine) systems ...
EXCELLENT Condition.Aphasia, dementia, traumatic brain injury, TBI, stroke, cognitive disorders, communication disorders, right ... Neurogenic Disorders of Language and Cognition: Evidence-based Clinical Practice by Pro Ed at Translate This Website. Hurry! ... Neurogenic Disorders of Language and Cognition: Evidence-based Clinical Practice. Neurogenic Disorders of Language and ... Neurogenic Disorders of Language and Cognition: Evidence-based Clinical Practice. 4.5 out of 5 stars with 95 reviews ...
The ARC Centre of Excellence in Cognition and its Disorders explores theories of cognition, diagnostic and treatment models in ... ARC Centre of Excellence in Cognition and its Disorders ARC Centre of Excellence in Cognition and its Disorders ... Delivering treatments and outcomes for people with cognitive disorders.. The ARC Centre of Excellence in Cognition and its ... is a collaborative hub for the study of the cognitive sciences and the diagnosis and treatment of cognitive disorders. ...
Copyright CCD - ARC Centre of Excellence in Cognition and its Disorders , Privacy Statement , Accessibility Information. Site ... The mission of the ARC Centre of Excellence in Cognition and its Disorders (CCD) is to coordinate and conduct research in five ... ARC Centre of Excellence in Cognition and its Disorders. The ARC Centre of Excellence offers unique opportunities for ... Dr Nan Xu Rattanasone, Postdoctoral Research Fellow, ARC Centre of Excellence in Cognition and its Disorders (CCD) explains. ...
... bipolar disorder, borderline personality disorder, major depressive disorder, or post-traumatic stress disorder. ... The article is "Early life experiences and social cognition in major psychiatric disorders: A systematic review," by Karolina I ... Childhood trauma linked to impaired social cognition later in life for patients with major psychiatric disorders. ... The purpose of the EPA is to improve the lives of patients with psychiatric disorders and to promote professional excellence ...
Buy Developmental Disorders of Language Learning and Cognition by Charles Hulme, Margaret J. Snowling from Waterstones today! ... Developmental Disorders of Language Learning and Cognition (Paperback). Charles Hulme (author), Margaret J. Snowling (author) ... This important new text is a comprehensive survey of current thinking and research on a wide range of developmental disorders. ... Politics, Society & Education > Psychology > Cognition & cognitive psychology Science, Technology & Medicine > Medicine > ...
Underlying Nonpharmacological Interventions for Cognition and Behavior in Neurological and Neuropsychiatric Disorders. Call for ... New nonpharmacological interventions in patients with neurological and neuropsychiatric disorders have shown important ... or remediation of patients with neurological and psychiatric disorders (acquired brain injury and neurodegenerative, ... neurodevelopmental, or neuropsychiatry disorders) measured with neuroimaging methods. *Cortex plasticity changes in ...
In support of improving patient care, Audio Digest Foundation is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. The Audio Digest Foundation designates this enduring material for a maximum of {{CurrentLecture.Lecture.Credits , number:2}} AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to {{CurrentLecture.Lecture.Credits}} MOC points [and patient safety MOC credit] in the American Board of Internal Medicines (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the ...
... the different domains of social cognition and a possible relationship with major depressive disorder, (ii) the clinical ... the different domains of social cognition and a possible relationship with major depressive disorder, (ii) the clinical ... Electronic databases were searched to identify clinical studies investigating social cognition in a major depressive disorder ... Electronic databases were searched to identify clinical studies investigating social cognition in a major depressive disorder ...
... the functional neuroanatomy of social cognition in either disorder remains unclear due to variability in primary literature. ... Both disorders were associated with hypoactivation within the Superior Temporal Sulcus (STS) during ToM tasks, but activation ... Conclusions Reduced frontolimbic and STS engagement emerged as a shared feature of social cognition deficits in SZ and ASD. ... Objective To identify regions most robustly implicated in social cognition processing in SZ and ASD. Data Sources Systematic ...
Effects of oxytocin on cognition and mood in binge eating disorder The Hormon Oxytocin. Oxytocin is a neurotransmitter that is ... Effects of oxytocin on cognition and mood in binge eating disorder. *Effectivity of a body image training in women with bulimia ... Effects of oxytocin on cognition and mood in binge eating disorder. *Effectivity of a body image training in women with bulimia ... Binge eating disorder. Patients with binge eating disorder regularly suffer from eating attacks during which they eat a huge ...
Interest in social cognition in bipolar disorder (BD) has increased considerably over the past decade, with studies ... bipolar disorder: Is there a connection?". Interest in social cognition in bipolar disorder (BD) has increased considerably ... Functional Remediation for Bipolar Disorder. Bipolar Disorder is a major mood disorder with periodic mood episodes that may be ... Bipolar disorder (BD) patients also have cognitive, social, and.... Early life experiences and social cognition in major ...
Katharyn Eve Lewandowski shows that cognitive remediation improves cognitive function in patients with bipolar disorder. ...
You are here: Managing stress and cognition in stress-related disorders: A digital coach for a sustainable life ... Managing stress and cognition in stress-related disorders: A digital coach for a sustainable life ... Research project In order to provide individuals instruments for managing stress and cognition in stress-related disorders, an ...
Language and communication skills in preschool children with autism spectrum disorders: Contribution of cognition, severity of ... We have in a number of studies investigated medical decision-making capacity and cognition in dementia, and also if it is ... One main project concerns how persons with acquired cognitive impairment with language and communication disorders are able to ... A second research area concerns language and communication development in preschool children with autism spectrum disorders and ...
... bipolar disorder, language disorders, stuttering, autism, obsessive-compulsive disorder, posttraumatic stress disorder, ... Psychiatric disorders. A wide range of psychiatric disorders, including schizophrenia, chronic depression, bipolar disorder, ... White matter in cognition and mental illness. A surprisingly diverse range of psychiatric and nervous system disorders are ... suggest that white matter is a contributing cause of many disorders affecting mood or cognition. Moreover, as will be described ...
... a study on cognition in bipolar disorder, schizophrenia patients, relatives and controls - Volume 46 Issue 4 - A. Vreeker, M. P ... High educational performance is a distinctive feature of bipolar disorder: ... High educational performance is a distinctive feature of bipolar disorder: a study on cognition in bipolar disorder, ... High educational performance is a distinctive feature of bipolar disorder: a study on cognition in bipolar disorder, ...
Buy the Paperback Book Cognition and Acquired Language Disorders by Richard K. Peach at Indigo.ca, Canadas largest bookstore ... Cognition and Acquired Language Disorders: An Information Processing Approach. byRichard K. Peach, Lewis P. ShapiroEditor ... Title:Cognition and Acquired Language Disorders: An Information Processing ApproachFormat:PaperbackDimensions:368 pages, 9.25 ... Section 3: Cognition and Acquired Language Disorders 8. Language and Communication Disordersr Associated with Attentional ...
Patients with Post Traumatic Stress Disorder (PTSD) Show Decreased Cognitive Control. Members of the BCLG examined the ...
Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study. The safety and ...
  • MIAMI - A drug that for years has been approved to treat moderate to severe Alzheimer's disease may have a role in improving the cognitive deficits associated with bipolar disorder. (medscape.com)
  • Subjects with bipolar disorder have significant cognitive and functional deficits, even when they are euthymic," lead author Dan Iosifescu, MD, director, Mood and Anxiety Disorders Program, Icahn School of Medicine at Mount Sinai, New York City, told Medscape Medical News . (medscape.com)
  • Schizophrenia and autism both feature significant impairments in social cognition and social functioning, but the specificity and mechanisms of these deficits remain unknown. (nih.gov)
  • Recent research suggests that social cognitive deficits in both disorders may arise from dysfunctions in the neural systems that underlie social cognition. (nih.gov)
  • The purpose of the present study is to evaluate a neuroplasticity-oriented, computer-based cognitive remediation treatment program in patients with bipolar disorder and its effects on cognitive deficits and community functioning compared to an active, computer-based control. (clinicaltrials.gov)
  • Deficits in social cognitive function are a hallmark feature of major psychiatric disorders resulting in impaired social and occupational functioning, specifically with regards to emotion recognition and regulation, theory of mind (the ability to attribute mental states to oneself and others), attributional style, and social perception. (elsevier.com)
  • The fact that these deficits are not generally improved by antipsychotic medication makes social cognition an important treatment target and the development of a causal working model of the deficits of crucial importance," noted Prof. Donohoe. (elsevier.com)
  • Additionally, it is not known whether deficits in ASD and SZ arise from similar or disease-specific disruption of the social cognition network. (plos.org)
  • Reduced frontolimbic and STS engagement emerged as a shared feature of social cognition deficits in SZ and ASD. (plos.org)
  • Cognitive and functional deficits in bipolar disorder and schizophrenia as a function of the presence and history of psychosis. (bioportfolio.com)
  • This approach facilitates the description and treatment of acquired language disorders across many neurologic groups when particular cognitive deficits are identified. (indigo.ca)
  • These protocols provide students and clinicians a ready clinical resource for managing language disorders due to deficits in attention, memory, linguistic operations, and executive functions. (indigo.ca)
  • Yet, research focusing on social cognition deficits in ADHD that accounts for subtype differences is limited. (utexas.edu)
  • Cognitive deficits are often seen in obsessive-compulsive disorder (OCD) or other disorders of impulsivity, reflecting underlying dysfunction of neurotransmitter function and cortico-subcortical circuitry 1-3, 4 . (cambridgecognition.com)
  • This resource provides a succinct summary of cognitive deficits reported in patients with major depressive disorder (MDD) with a particular focus on aspects of measurement, underlying disease pathophysiology, implications for treatment and prevention. (oup.com)
  • Objectives: Neuropsychological studies comparing patients with bipolar disorder (BD) to patients with schizophrenia (SZ) suggest milder cognitive deficits in BD patients and across a smaller range of functions. (ncirl.ie)
  • The deficits include attention, vigilance, and other measures of cognition, including memory and complex decision making. (nih.gov)
  • It is unclear whether cognitive deficits are apparent prior to the onset of bipolar disorder or whether they develop during the course of the illness. (edu.au)
  • Assessing cognitive ability in people with a first-episode of bipolar disorder helps determine whether cognitive deficits were apparent prior to illness onset. (edu.au)
  • Contrary to reports among non-psychiatric patients, cannabis may improve cognition among people with bipolar disorder. (centerwatch.com)
  • Since elevated levels of the klotho protein appear to improve cognition throughout the lifespan, raising klotho levels could build cognitive reserve as a bulwark against the disease. (ucsf.edu)
  • Several drugs approved for dementia stimulate acetylcholine by blocking its breakdown, which has been shown to improve cognition and slow cognitive decline. (blogspot.co.uk)
  • 8 Autism Spectrum Disorder. (wiley.com)
  • Background: Since social cognition is impaired in individuals with autism spectrum disorder (ASD), this study aimed at establishing the efficacy of a newly developed imitation- and synchronization-based dance/movement intervention (SI-DMI) in fostering emotion inference and empathic feelings (emotional reaction to feelings of others) in adults with high-functioning ASD. (hu-berlin.de)
  • Brief report: Atypical social cognition and social behaviours in autism spectrum disorder: A different way of processing rather than an impairment. (researchautism.net)
  • The parenting experiences of mothers in a family with a child with autism spectrum disorder (ASD) and a typically developing (TD) child were studied using a qualitative analysis of mothers' perceptions of the impact of autism on family and personal life. (ed.gov)
  • Alexithymia is a personality trait frequently found in adults with autism spectrum disorder (ASD), and has been linked to impairments in emotion recognition and empathy. (kcl.ac.uk)
  • The presence of autism-related traits has been well documented in undiagnosed family members of individuals with autism spectrum disorder (ASD). (hindawi.com)
  • Autism Spectrum Disorder (ASD), including Autistic Disorder, Asperger's Disorder, and Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS), is both genetically and phenotypically heterogeneous. (hindawi.com)
  • New nonpharmacological interventions in patients with neurological and neuropsychiatric disorders have shown important cognitive and behavior improvements related to synaptic plasticity changes in the underlying brain mechanisms. (hindawi.com)
  • This special issue will present evidence of the efficacy and neural plasticity mechanisms of nonpharmacological cognitive and behavior interventions in patients with acquired brain injury and neurodegenerative and neuropsychiatric disorders. (hindawi.com)
  • People with bipolar disorder often show more approach-related behavior and positive appraisals of others during social interactions. (bioportfolio.com)
  • A personality disorder in which there are oddities of thought (magical thinking, paranoid ideation, suspiciousness), perception (illusions, depersonalization), speech (digressive, vague, overelaborate), and behavior (inappropriate affect in social interactions, frequently social isolation) that are not severe enough to characterize schizophrenia. (bioportfolio.com)
  • Patients with major depressive disorder appear to interpret social cognitive stimuli differently to healthy controls: depressed individuals may interpret emotion through a mood-congruent bias and have difficulty with cognitive theory of mind tasks requiring interpretation of complex mental states. (frontiersin.org)
  • Methods: We investigated 22 patients with BPD, 23 patients with Cluster C personality disorder (CPD), and 24 nonpatients on facial emotion recognition and social evaluation before and after stress induction based on the Trier Social Stress Test (TSST). (uva.nl)
  • This second edition of the highly praised Cognition and Emotion examines everything from past philosophical to current psychological perspectives in order to offer a novel understanding of both normal emotional experience and the emotional disorders. (google.com.mx)
  • Although there are many influential theories of normal emotions within the cognition and emotion literature, these theories rarely address the issue of disordered emotions. (google.com.mx)
  • It also provides a core cognition and emotion textbook through the inclusion of a comprehensive review of the basic literature. (google.com.mx)
  • The book includes chapters on the historical background and philosophy of emotion, reviews the main theories of normal emotions and of emotional disorders, and includes separate chapters organised around the five basic emotions of fear, sadness, anger, disgust, and happiness. (google.com.mx)
  • Cognition and Emotion: From Order to Disorder provides both an advanced textbook for undergraduate and postgraduate courses in addition to a novel approach with a range of implications for clinical practice for work with the emotional disorders. (google.com.mx)
  • His main research interests include psychological reactions to trauma and cognition-emotion relations in the emotional disorders. (google.com.mx)
  • Cognition and Emotion: America Foreign Brides, Family Ties, and New World Masculinity Dramatizing Consent: The Universal Charms of American Democracy submitting Liberties: books of a combined Cosmopolitanism 5 THE GENRES OF DEMOCRACY Does Democracy are a Genre? (bde-info.com)
  • easy Cognition and Emotion: From Order to can Add from the pregnant. (bde-info.com)
  • Please match thereby and send your Cognition and Emotion: directly, or adopt the limit not to keep a inquiry-based province. (bde-info.com)
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  • The present study investigated whether this pattern is also true for social cognition - a range of socially relevant abilities, including emotion perception and recognition, theory of mind, and social attributions - by comparing performance on measures of social cognition in patients with BD, SZ, and healthy participants. (ncirl.ie)
  • Your download cognition and emotion from left a time that this computer could Now write. (eiti-prien.de)
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  • Edited by leading figures in the field, this handbook gives an overview of the current status of cognition and emotion research by giving the historical background to the debate and the philosophical arguments before moving on to outline the general aspects of the various research traditions. (wiley.com)
  • The Philosophy of Cognition and Emotion (W. Lyons). (wiley.com)
  • Research Methods in Cognition and Emotion (W. Parrott & P. Hertel). (wiley.com)
  • Inhibition Processes in Cognition and Emotion: A Special Case (T. Dalgleish, et al. (wiley.com)
  • Multi-Level Theories of Cognition-Emotion Relations (J. Teasdale). (wiley.com)
  • Forensic Applications of Theories of Cognition and Emotion (D. Bekerian & S. Goodrich). (wiley.com)
  • Cognition and Emotion: Future Directions (T. Dalgleish & M. Power). (wiley.com)
  • This book is an important reference for use by researchers in cognition and emotion and will be of value to anyone who has interests that overlap this area. (wiley.com)
  • Put simply, hot cognition is cognition coloured by emotion. (wikipedia.org)
  • As it is automatic, rapid and led by emotion, hot cognition may consequently cause biased and low-quality decision making. (wikipedia.org)
  • Hot cognition may arise, with varying degrees of strength, in politics, religion, and other sociopolitical contexts because of moral issues, which are inevitably tied to emotion. (wikipedia.org)
  • Hot cognition is likely to be utilized during tasks that require the regulation of emotion or motivation, as well as the re-evaluation of the motivational significance of a stimulus. (wikipedia.org)
  • Mood disorders are common, complex and costly neuropsychiatric disorders which occur at all ages and in all demographic groups. (frontiersin.org)
  • Neuropsychiatric Disorders and Cognition Conference aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Neuropsychiatric Disorders and Cognition Conference. (waset.org)
  • It also provides a premier interdisciplinary platform for researchers, practitioners, and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of Neuropsychiatric Disorders and Cognition Conference. (waset.org)
  • Addresses age-related cognitive and neuropsychiatric disorders that are of particular importance with the rapid expansion of the aging population. (jhsph.edu)
  • Predoctoral and Postdoctoral students from A&S, SPH and SOM students participating in the NIA Training Program on Age-Related, Cognitive and Neuropsychiatric Disorders are required to take this course. (jhsph.edu)
  • Obsessive compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive ritualistic behaviors and has been associated with diverse functional brain abnormalities. (nih.gov)
  • Aaron Clarke from the University of Hertfordshire is working on a thesis project that he is hoping will lead to further understanding of Obsessive Compulsive Disorder and to hopefully diminish its stigma. (ocdaction.org.uk)
  • A recent study finds evidence for why hoarders might be considered separate from those suffering from obsessive-compulsive disorder. (scientificamerican.com)
  • The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers. (cambridgecognition.com)
  • Cognitive functioning in obsessive-compulsive disorder: a meta-analysis. (cambridgecognition.com)
  • Öst LG, Havnen A, Hansen B, Kvale G. Cognitive behavioral treatments of obsessive-compulsive disorder. (cambridgecognition.com)
  • Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation. (cambridgecognition.com)
  • Impaired cognitive flexibility and motor inhibition in unaffected first-degree relatives of patients with obsessive-compulsive disorder. (cambridgecognition.com)
  • Chamberlain SR, Menzies L. Endophenotypes of obsessive-compulsive disorder: rationale, evidence and future potential. (cambridgecognition.com)
  • Cognitive impairment in patients with mood disorders is being recognised as a significant factor that can have an impact on patients' ability to function and on their recovery from their mood disorder and as a result is viewed as a target for therapeutic intervention. (frontiersin.org)
  • the relationship between treatment and cognition and the evidence of emerging benefits of various treatment modalities on cognitive impairment in mood disorders. (frontiersin.org)
  • 3 Reading Disorders II: Reading Comprehension Impairment. (wiley.com)
  • The impact of depression on social cognitive functioning is less well understood, although there is some evidence to suggest that a similar, albeit less severe, impairment of social cognition may be seen in patients with major depressive disorder. (frontiersin.org)
  • Impairment in social cognition is a cardinal feature of the clinical presentation of both ASD and SZ [4] - [8] . (plos.org)
  • One main project concerns how persons with acquired cognitive impairment with language and communication disorders are able to participate in decisions about their own medical treatment. (ki.se)
  • Their study found distinct cognitive impairment patterns that correspond with the disorder. (genome.gov)
  • The Center focuses on advancing research and clinical practice on genetic disorders associated with severe cognitive and behavioral impairment. (kennedykrieger.org)
  • In this article, the author reviews a simple approach to a symptom-based differential diagnosis, including recognition of impairment in several key cognitive domains as well as associated symptoms such as motor disorders, psychosis, and sleep disturbance. (elsevier.com)
  • PHP1A (pseudohypoparathyroidism 1A) is a rare genetic disorder that causes short adult stature, multi-hormone resistance, early-onset obesity and cognitive impairment. (vumc.org)
  • Through a comprehensive review of all research conducted to date, the investigators established that a traumatic early social environment frequently leads to social cognitive problems and greater illness severity for individuals with schizophrenia, bipolar disorder, borderline personality disorder, major depressive disorder, or post-traumatic stress disorder. (elsevier.com)
  • Similarly, there are numerous theories that seek to explain one or more emotional disorders (e.g., depression, post-traumatic stress disorder, and phobias), but which rarely discuss normal emotions. (google.com.mx)
  • OBJECTIVE: Trauma-exposed individuals with post-traumatic stress disorder (PTSD) display reduced amygdala and hippocampal size and impaired cognition. (uzh.ch)
  • What is post-traumatic stress disorder? (healthline.com)
  • Post-traumatic stress disorder (PTSD) is a debilitating trauma- and stressor-related disorder that can occur after experiencing or witnessing a traumatic event. (healthline.com)
  • The term social cognition refers to a complex set of processes subserving adaptive social interaction which depend on "theory of mind", or in other words, the ability to make correct attributions of the mental states of others [9] - [10] . (plos.org)
  • The term social cognition refers to how social information is processed. (bioportfolio.com)
  • Nevertheless, depressed patients appear to be less severely impaired in social cognition than patients with schizophrenia or autism ( 7 - 9 ). (frontiersin.org)
  • Traditionally defined by symptom clusters (i.e., mania, depression or mixtures thereof), it is now increasingly recognised that other aspects of these disorders may play an important role in the fundamental disease processes and the mechanism of action of treatments. (frontiersin.org)
  • The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) includes cognitive symptoms as one of the nine diagnostic criteria for major depressive episode which can occur in the context of major depression or bipolar disorder. (frontiersin.org)
  • Indeed, there is evidence that cognitive dysfunction is not just a proxy measure that can be used in testing for drug discovery - it has an impact on real-world functioning and is therefore a major contributor to the economic burden of depression and bipolar disorders. (frontiersin.org)
  • The aim of this review is to characterize the current understanding of: (i) the different domains of social cognition and a possible relationship with major depressive disorder, (ii) the clinical presentation of social cognition in acute and remitted depressive states, and (iii) the effect of severity of depression on social cognitive performance. (frontiersin.org)
  • Whilst major depressive disorder is primarily characterized by emotional symptoms such as low mood and anhedonia ( 5 ), individuals with depression have also been found to display profound and pervasive impairments in interpersonal functioning ( 6 ). (frontiersin.org)
  • The majority of data from previous reviews investigating the relationship between depression and social cognition relate primarily to the emotional domain, particularly through facial expressions or affective theory of mind. (frontiersin.org)
  • Previously of interest in demyelinating diseases such as multiple sclerosis, myelin is attracting new interest as an unexpected contributor to a wide range of psychiatric disorders, including depression and schizophrenia. (pubmedcentralcanada.ca)
  • and to compare measures of mood and cognition on wearable technology using traditional neuropsychological testing and patient reported outcomes on depression symptoms at 6 weeks. (perssupport.nl)
  • Strong associations were found between mothers' symptoms of stress and depression, and their parenting cognitions about both their children. (ed.gov)
  • Indeed, patients may think they have attention-deficit disorder or, if older, Alzheimer's disease. (frontiersin.org)
  • Patients who have Alzheimer's disease and related disorders are really facing complex and devastating conditions that often impact on every aspect of a person's life. (brighamandwomens.org)
  • Neurogenic Disorders of Language and Cognition: Evidence-based Clinical Practice by Pro Ed at Translate This Website. (translateth.is)
  • The second edition of Neurogenic Disorders of Language and Cognition: Evidence-Based Clinical Practice provides a thorough and updated review of acquired neurogenic language and cognitive disorders including aphasia, traumatic brain injury, right hemisphere cognitive-communication disorders, and dementia. (proedaust.com.au)
  • A online video and writing samples to illustrate some of the different neurogenic disorders and assessment and treatment procedures. (proedaust.com.au)
  • ADHD is a well researched disorder in children and is associated with impairments in social functioning (Barkley, 2006). (utexas.edu)
  • A second research area concerns language and communication development in preschool children with autism spectrum disorders and a third area concerns socio-emotional development in children with communication and language disorders. (ki.se)
  • This new graduate level textbook, Cognition and Acquired Language Disorders: An Information Processing Approach , addresses the cognitive aspects of language and communication. (indigo.ca)
  • It assembles the most recent information on this topic, addressing normal cognitive processing for language in adults, the cognitive impairments underlying language disorders arising from a variety of neurologic conditions, and current assessment and treatment strategies for the management of these disorders. (indigo.ca)
  • The text is organized using an information processing approach to acquired language disorders, and thus can be set apart from texts that rely upon a more traditional, syndrome-based approach (e.g., stroke, dementia, and traumatic brain injury). (indigo.ca)
  • This chapter examines how stroke, a common neurological disease seen in aging, leads to language disorders. (oup.com)
  • Empirical studies following this line of research initially focused on rates of cognitive disorders, such as intellectual disability, learning disabilities, and language disorders, in family members without a diagnosis of ASD. (hindawi.com)
  • Cognitive dysfunction is increasingly recognized as a major feature of bipolar disorder (BD), present by illness onset, persistent into euthymia, and associated with functional outcome. (clinicaltrials.gov)
  • Cognitive dysfunction is a common feature of bipolar disorder that exists across a number of cognitive domains and usually persists in remission. (edu.au)
  • A medical condition that has been reported in some veterans of the Gulf War, characterized by a multitude of symptoms including chronic fatigue, headache, joint pain, eczema, dyspepsia, neurologic dysfunction, and respiratory disorders, and attributed to exposure to toxic chemicals. (thefreedictionary.com)
  • In a randomized, controlled, parallel-arm clinical trial of adjuvant memantine vs placebo in euthymic patients with bipolar disorder, memantine improved several cognitive domains and also demonstrated increased hippocampus neuronal viability on imaging scans of the brain. (medscape.com)
  • So we saw that people did better on tests of cognition, and also saw biological changes occurring at the same time in the brain. (medscape.com)
  • A research team has identified a network of genes in the brain that regulates normal cognitive abilities but is also implicated with a range of neurodevelopmental disorders, such as autism, epilepsy, intellectual disability, and schizophrenia . (psychcentral.com)
  • We believe that studying gene networks in the brain can give us extra clues about the genetic cause of neurodevelopmental disorders and of their neurological comorbidities," said Associate Professor Enrico Petretto, senior co-author of the study and head of the Systems Genetics of Complex Disease Laboratory at Duke-NUS. (psychcentral.com)
  • The results of our study in the human brain show a previously unappreciated functional relationship between cognition and neurodevelopmental disorders' genes. (psychcentral.com)
  • We explored the neural activation of discrete brain regions implicated in social cognitive and face processing in schizophrenia subgroups and autism spectrum disorders during complex social judgments of faces. (nih.gov)
  • Tim Dalgleish is a Senior Research Scientist and practising clinical psychologist at the Medical Research Council Cognition and Brain Sciences Unit in Cambridge. (google.com.mx)
  • Cognition Kit takes research out of the lab and into daily life, enabling doctors, scientists and the public to better understand and manage brain health and enhance patient care. (perssupport.nl)
  • We hypothesized that impaired fasting glucose (IFG) and incident glucose disorders have detrimental effects on global cognition and brain volume. (garvan.org.au)
  • Primary outcomes were global cognition and total brain volume. (garvan.org.au)
  • Stable IFG did not show greater decline in global cognition or brain volumes compared to normal. (garvan.org.au)
  • Incident glucose disorders, like diabetes, are associated with accelerated decline in global cognition and brain volumes in non-demented elderly, whereas stable IFG is not. (garvan.org.au)
  • In conjunction with these studies, an understanding of the functional implications of derived anatomical traits is gained through analyses of neurodevelopmental disorders, which help to define a spectrum of variation in the diversity of human brain phenotypes. (escholarship.org)
  • Background: Converging lines of evidence suggest that Brain-Derived Neurotrophic Factor (BDNF) may play a central role in the pathogenesis of Bipolar Disorder (BD), thus representing a valid biomarker of the disease. (elsevier.com)
  • Further and larger genetic studies are required in order to detect association between BDNF polymorphism, BDNF levels, brain abnormalities and cognition in BD. (elsevier.com)
  • While Parkinson's disease is widely known as a motion disorder, it affects other areas of the brain including cognition. (uctv.tv)
  • A new report published in European Psychiatry identified a significant association between childhood adversity and impaired social cognitive functioning among adults diagnosed with major psychiatric disorders. (elsevier.com)
  • Traumatic childhood experiences -- such as emotional and physical abuse and neglect, early loss of caregivers, and insecure attachment styles -- are frequently reported in as high as 85 percent of patients with various psychiatric disorders. (elsevier.com)
  • These findings are relevant to gain a better understanding the mechanisms between a traumatic early social environment and subsequent social cognitive problems and increased illness severity for a range of major psychiatric disorders in adulthood. (elsevier.com)
  • The article is "Early life experiences and social cognition in major psychiatric disorders: A systematic review," by Karolina I. Rokita, Maria R. Dauvermann, and Gary Donohoe ( https://doi.org/10.1016/j.eurpsy.2018.06.006 ). (elsevier.com)
  • Social cognitive performance is recognized to be impaired in several psychiatric conditions, but the relationship with major depressive disorder is less well understood. (frontiersin.org)
  • Early life experiences and social cognition in major psychiatric disorders: A systematic review. (bioportfolio.com)
  • To present a systematic review of the literature on the associations between early social environment, early life adversity, and social cognition in major psychiatric disorders, including schizophreni. (bioportfolio.com)
  • Recently, unanticipated changes in myelin genes and alterations in white matter structure have been observed in a wide range of psychiatric disorders. (pubmedcentralcanada.ca)
  • A surprisingly diverse range of psychiatric and nervous system disorders are accompanied by changes in white matter structure or abnormalities in myelin genes (see Box 1 ). (pubmedcentralcanada.ca)
  • Many neurological disorders result from damage or disease affecting the myelin sheath on nerve fibers, but recently, white matter defects have also been associated with a wide range of psychiatric and neurological disorders. (pubmedcentralcanada.ca)
  • These studies will provide information that effectively bridges the fields of addiction and general psychiatry, informing treatment development for co-morbid substance abuse and psychiatric disorders. (centerwatch.com)
  • According to the American Psychiatric Association (APA), authors of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-V), MDD is a combination of symptoms that affects how you feel, the way you think and how you act. (perssupport.nl)
  • This could hold potential implications of a better understanding of this psychiatric disorder by identifying causal agents or maintenance influences. (ocdaction.org.uk)
  • Delivering treatments and outcomes for people with cognitive disorders. (edu.au)
  • Cognition Kit is a software platform for mobile and wearable technology, designed to capture high frequency patient-centered outcomes. (perssupport.nl)
  • An emerging body of literature is beginning to address the possible role social cognition may share in the social functioning outcomes in children with ADHD (Buitelaar et al. (utexas.edu)
  • These impairments have been shown to be associated with various impaired functional outcomes and thus development of new therapies to enhance cognition has become one of the most pressing challenges. (blogspot.co.uk)
  • By contrast, trauma-exposed subjects with DA or DID (n = 13) displayed normal amygdala and hippocampal size and normal cognition. (uzh.ch)
  • The papers in this Research Topic will review a number of aspects of cognition in mood disorders which are important areas of clinical and research focus. (frontiersin.org)
  • The different research projects all aim at investigating how disturbed language and communication relates to aspects of cognition and interaction. (ki.se)
  • The relationship between cognition and physiology is bi-directional, meaning that cognition can effect physiology and vice versa. (bartleby.com)
  • The findings offer an alternate starting point for scientists to develop therapies for these debilitating disorders. (psychcentral.com)
  • This book will be indispensable in providing a broad understanding of the field for researchers specialising in specific disorders and the sections on the application of research findings to treatment interventions will be of particular interest to clinicians. (wiley.com)
  • These findings lend support to models hypothesizing well-defined neural substrates of social cognition and suggest a specific neural mechanism that may underlie social cognitive impairments in both autism and paranoid schizophrenia. (nih.gov)
  • Scientists from multiple disciplines come to the ARC to link theoretical models and research findings in the cognitive sciences that will benefit those with cognitive disorders. (edu.au)
  • The potential of a mobile app as a valid and easily accessible tool for measuring cognitive function in adults with major depressive disorder (MDD) was demonstrated in study findings presented at the Psych Congress 2020, held virtually from September 10 to 13, 2020. (clinicaladvisor.com)
  • The VaD patients with insular lesions exhibited impaired Taste Cognition Test findings. (unboundmedicine.com)
  • Our goal in this chapter is to present the findings from two U.K. studies into the instrumental and relational nature of public judgements about what characterises disorder. (surrey.ac.uk)
  • The team's report is the first to link the KL-VS variant, or allele, to better cognition in humans, and buttresses these findings with genetic, electrophysiological, biochemical and behavioral experiments in mice. (ucsf.edu)
  • Is the Subject Area "Social cognition" applicable to this article? (plos.org)
  • All groups showed significant activation of a social cognitive network including the amygdala, fusiform face area (FFA), superior temporal sulcus (STS), and ventrolateral prefrontal cortex (VLPFC) while completing a task of complex social cognition (i.e. trustworthiness judgments). (nih.gov)
  • Social cognition - the ability to identify, perceive, and interpret socially relevant information - is an important skill that plays a significant role in successful interpersonal functioning. (frontiersin.org)
  • Electronic databases were searched to identify clinical studies investigating social cognition in a major depressive disorder population, yielding 31 studies for this review. (frontiersin.org)
  • The difficulties with social interaction observed in major depressive disorder may, at least in part, be due to an altered ability to correctly interpret emotional stimuli and mental states. (frontiersin.org)
  • Together, these skills are referred to as social cognition and are an important component of cognitive functioning. (frontiersin.org)
  • Social cognition encompasses the identification, perception, and interpretation of socially important information ( 1 ), whilst the domain of theory of mind specifically refers to the ability to infer information regarding the thoughts, intentions, and feelings of others ( 2 ). (frontiersin.org)
  • Impaired social cognition is a cardinal feature of Autism Spectrum Disorders (ASD) and Schizophrenia (SZ). (plos.org)
  • However, the functional neuroanatomy of social cognition in either disorder remains unclear due to variability in primary literature. (plos.org)
  • To identify regions most robustly implicated in social cognition processing in SZ and ASD. (plos.org)
  • Sugranyes G, Kyriakopoulos M, Corrigall R, Taylor E, Frangou S (2011) Autism Spectrum Disorders and Schizophrenia: Meta-Analysis of the Neural Correlates of Social Cognition. (plos.org)
  • Neurobiological models of social cognition implicate an extended neural network in processing social stimuli [11] - [15] . (plos.org)
  • Functional outcome and social cognition in bipolar disorder: Is there a connection? (bioportfolio.com)
  • schizophrenia , but there is still little information about links between social cognition and social functioning in BD. (bioportfolio.com)
  • Our aim was therefore to review the relationship between functional outcome and social cognition in patients with BD. (bioportfolio.com)
  • Social cognition moderates the relationship between neurocognition and community functioning in bipolar disorder. (bioportfolio.com)
  • Schizophrenia (SZ) studies suggest that neurocognition predicts functional outcome and that social cognition mediates this relationship. (bioportfolio.com)
  • Bipolar disorder (BD) patients also have cognitive, social, and. (bioportfolio.com)
  • Theory of mind (TOM), a main component of social cognition processes, refers to the capacity to infer one's own and other person's mental states. (bioportfolio.com)
  • A personality disorder manifested by a profound defect in the ability to form social relationships, no desire for social involvement, and an indifference to praise or criticism. (bioportfolio.com)
  • In this study we investigated stress reactivity in BPD and its interference with social cognition, and tested whether any differences are specific for BPD or are inherent to personality disorders in general. (uva.nl)
  • Conclusion: These results suggest that heightened psychological reactivity in BPD co-occurs with attenuated physiological responses to psychosocial stress and that stress affects social cognition to a similar extent in BPD as in others. (uva.nl)
  • Malleability of Social Cognition and Communication Development in Toddlers with Autism Spectrum Disorders: Insights from an Early Intervention Study, Rebecca Landa, PhD. (utdallas.edu)
  • Home / Test Division / Reference Database / 2010 to 2017 / 2014 / Social cognition and levels of personality organization in patients with somatoform. (umn.edu)
  • Particular interests of the Center are the neurobiologic bases of intellectual disability, autism in intellectual disability, and social avoidance and other aberrant behaviors in these disorders. (kennedykrieger.org)
  • Measures of social cognition did not predict ADHD subtype, and when compared to a normative sample, participants performed in the average range on affect recognition and theory of mind tasks. (utexas.edu)
  • Executive functioning, not social cognition, was predictive of social maladjustment in CT and PI youth. (utexas.edu)
  • Neighbourhood disorder refers to those cues in one's social and physical environment that signal first the erosion of shared commitments to dominant norms and values, and second the failure of community members and authorities to regulate behaviour in public space. (surrey.ac.uk)
  • We frame our discussion in the context of psychological work on motivated social cognition - i.e. the ways in which various psychological needs, goals and desires (a) shape information processing and (b) lead to conclusions that individuals wish to reach rather than ones demanded by adherence to logic and/or evidence. (surrey.ac.uk)
  • Are retinoids potential therapeutic agents in disorders of social cognition including autism? (nus.edu.sg)
  • We believe that RISC will prove highly constructive as a tool in future research on social cognition, inter-personal communication, and the interpretation of speaker intentions in both healthy adults and clinical populations. (mcgill.ca)
  • Methods: One hundred and two patients with BD, 208 patients with SZ, and 132 healthy participants were assessed using a battery of tasks measuring basic neuropsychological and social cognition. (ncirl.ie)
  • Handbook of Social Cognition (Vol. 3, pp. 1-45). (springer.com)
  • Advances in social cognition (Vol. 1, pp. 1-36). (springer.com)
  • Handbook of social cognition (Vol. 1, pp. 120-160). (springer.com)
  • The trial was presented in a rapid communication session here at the 10th International Conference on Bipolar Disorders (ICBD). (medscape.com)
  • Modern diagnostic schemes differentiate between Major Depressive Disorder and Bipolar Disorders, but there is much overlap between these categories. (frontiersin.org)
  • Bipolar Disorders, 14 (7). (ncirl.ie)
  • For some types of cognition, the change was related to PTSD and/or depressive symptoms, supporting the notion that cognitive change is an important working mechanism of cognitive processing therapy. (medworm.com)
  • RESULTS: Compared with controls, trauma-exposed subjects with PTSD (n = 10) displayed significantly reduced amygdala and hippocampal size and significantly impaired cognition. (uzh.ch)
  • In the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders criteria for posttraumatic stress disorder (PTSD) incorporate trauma-related cognitions. (beckinstitute.org)
  • Posttraumatic stress disorder (PTSD) is associated with suicidal ideation (SI) and suicidal self-directed violence (SDV). (ovid.com)
  • Once known as "shell shock" or "battle fatigue," PTSD has received public attention because of the high number of war veterans with the disorder. (healthline.com)
  • The nature of cognitive training programs, often building on laboratory measures of cognition, may reduce how inherently interesting (i.e., fun) they are, limiting their uptake outside of paid research studies. (centerwatch.com)
  • The neurobehavioral impact extends from simple measures of cognition (i.e., attention and reaction time) to far more complex errors in judgment and decision making, such as medical errors, discussed below and in Box 4-1 . (nih.gov)
  • They rest on a foundation of causes and effects, interactions and events, emotions and cognitions, functions and dysfunctions that together form the individual and make him or her what s/he is. (blogspot.co.uk)
  • Such cognitive symptoms may persist after an episode of mood disorder so there may be residual symptoms, which has implications for the management of patients with mood disorders and for the ability to achieve functional recovery even after the episode ends. (frontiersin.org)
  • It also provides an opportunity for clinical-based assessment of cognition and recommendations for how cognitive measurement and treatment is positioned in the management of individuals with mood disorders. (oup.com)
  • Participants with incident glucose disorders had greater decline in global cognition and visuospatial function compared to normal, similar to that observed in baseline diabetes. (garvan.org.au)
  • Compared to people without bipolar disorder (controls), high quality evidence shows medium-sized effects of poorer global cognition and processing speed, and small effects of poorer premorbid IQ, working memory, fluency and reasoning in people with first-episode bipolar disorder. (edu.au)
  • The Center is characterized by integrating basic and clinical neuroscience through multidisciplinary research projects on genetic disorders traditionally grouped under the label of intellectual disabilities. (kennedykrieger.org)
  • The Master of Science in Applied Cognition and Neuroscience degree (ACN) provides students with advanced training that incorporates methodologies and approaches from such diverse fields as neuroscience, experimental psychology, artificial intelligence, and human-computer interactions. (utdallas.edu)
  • Students earning a master's degree in applied cognition and neuroscience specialize in one of six areas: neuroscience, cognition, cognition and neuroscience, human-computer interactions, computational modeling/intelligent systems, and neurological diagnosis and monitoring. (utdallas.edu)
  • Many courses in the applied cognition and neuroscience program are offered periodically as evening courses to meet the needs of busy professionals' schedules, and part-time students are welcome. (utdallas.edu)
  • The UT Dallas graduate catalog provides more information on the Master of Science in Applied Cognition and Neuroscience degree program. (utdallas.edu)
  • The Master of Science in Applied Cognition and Neuroscience degree provides students with coursework and training that span the fields of neuroscience, experimental psychology, artificial intelligence, and human-computer interactions. (utdallas.edu)
  • Admission to the Applied Cognition and Neuroscience Master's degree program is based on a review of the applicant's grade point average (GPA), scores on the Graduate Record Exam (GRE), three letters of recommendation and a "statement of purpose" essay describing the applicant's specific interests and career goals. (utdallas.edu)
  • Specific questions about applying to the applied cognition and neuroscience master's degree program should be directed to Melanie Davis . (utdallas.edu)
  • This video presentation provides students with an overview of the Master of Science in Applied Cognition and Neuroscience degree. (utdallas.edu)
  • Language and communication skills in preschool children with autism spectrum disorders: Contribution of cognition, severity of autism symptoms, and adaptive functioning to the variability. (ki.se)
  • The numeric staging does not concentrate solely on cognition but also takes into account neurobehavioral and functional symptoms. (mdedge.com)
  • It can be difficult to diagnose because people with the disorder may be reluctant to recall or discuss the trauma or their symptoms. (healthline.com)
  • 130 patients with BD with a history of psychosis recruited from the Psychotic Disorders Programs at McLean Hospital will be randomized into either the CR or computer control group. (clinicaltrials.gov)
  • Autism and psychotic disorders have historically been considered as related diagnostic entities. (plos.org)
  • Children with autism spectrum disorders who do not develop phrase speech in the preschool years. (ki.se)
  • Dr. Landa has consulted with schools and families on an international level to establish state-of-the-science educational programming for children with autism spectrum disorders. (utdallas.edu)
  • Schizophrenia is a primary psychotic disorder, whereas approximately half of people with bipolar disorder will experience psychosis. (bioportfolio.com)
  • Resting-state functional connectivity in individuals with bipolar disorder during clinical remission: a systematic review. (bioportfolio.com)
  • Studies investigating resting-state functional connectivity in individuals with bipolar disorder may help to inform neurobiological models of illness. (bioportfolio.com)
  • Systems biology presently suffers the same mereological and sufficiency fallacies that haunt neural network models of high order cognition. (cogprints.org)
  • Towards a unified, computationally-implemented neural network for understanding semantic cognition and its disorders. (neurodegenerationresearch.eu)
  • In several neurodevelopmental disorders, cognitive difficulty is reported as a core symptom. (psychcentral.com)
  • Analysing all data available to date, the team observed that about one-third of the genes in this network are mutated in various neurodevelopmental disorders. (psychcentral.com)
  • The identification of this gene network provides the starting point to develop precision medicine strategies to target the entire pathway or genes specific to neurodevelopmental disorders. (psychcentral.com)
  • Williams syndrome (WS) is a rare neurodevelopmental disorder caused by a hemideletion of ~1.6 Mb (25-28 genes) on human chromosome 7q11.23, a highly dynamic region associated with recent adaptive selection in hominoid lineages. (escholarship.org)
  • Analyzing the neuroanatomical phenotype in WS provides the unique opportunity to study correlates of a distinctive cognitive and behavioral phenotype in a neurodevelopmental disorder of known genetic cause. (escholarship.org)
  • Journal of Affective Disorders, Vol. 223, Issue. (cambridge.org)
  • Journal of Affective Disorders, Vol. 207, Issue. (cambridge.org)
  • Journal of Affective Disorders , 243 , 552-558. (elsevier.com)
  • Background: Borderline personality disorder (BPD) is characterized by severe difficulties in interpersonal relationships and emotional functioning. (uva.nl)
  • This article considers evidence that white matter is involved in learning, information-processing, neurological and psychological disorders. (pubmedcentralcanada.ca)
  • These surprising results pave a promising new avenue of research," said Roderick Corriveau, PhD, program director at NIH's National Institute of Neurological Disorders and Stroke (NINDS). (ucsf.edu)
  • Further research done on these neurological areas suggests there may be some plasticity during the development of both hot and cold cognition. (wikipedia.org)
  • Twelve individuals with autism spectrum disorders (ASD), 12 paranoid individuals with schizophrenia (P-SCZ), 12 non-paranoid individuals with schizophrenia (NP-SCZ), and 12 non-clinical healthy controls participated in this cross sectional study. (nih.gov)
  • Includes emphasis on contrasting the major neurodegenerative disorders related to age and describing the clinical presentation and pattern of cognitive change in each condition. (jhsph.edu)
  • 6 Developmental Coordination Disorder. (wiley.com)
  • Cold cognition is thought to be associated with executive functions elicited by abstract, deconceptualized tasks, such as card sorting. (wikipedia.org)
  • The child likely has been stricken with an inborn error of metabolism, a recessive genetic disorder that interferes with the normal digestion of food. (genome.gov)
  • Limitations: Few genetic studies exploring the impact of Val66Met on cognition in BD. (elsevier.com)
  • In spite of advances in its treatment, persons with HIV continue to develop HIV-associated neurocognitive disorders (HAND) over time. (centerwatch.com)
  • Therefore, the investigators propose to determine the effects of oral cannabinoid administration on cognitive domains relevant to bipolar disorder, e.g., arousal, decision making, cognitive control, inhibition, and temporal perception (sense of timing). (centerwatch.com)
  • Our recommended test battery for OCD and other impulse disorders assesses the key cognitive domains often impaired, as well as those that can be affected by interventions. (cambridgecognition.com)