Intellectual or mental process whereby an organism obtains knowledge.
Disturbances in mental processes related to learning, thinking, reasoning, and judgment.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
A set of cognitive functions that controls complex, goal-directed thought and behavior. Executive function involves multiple domains, such as CONCEPT FORMATION, goal management, cognitive flexibility, INHIBITION control, and WORKING MEMORY. Impaired executive function is seen in a range of disorders, e.g., SCHIZOPHRENIA; and ADHD.
The ability to attribute mental states (e.g., beliefs, desires, feelings, intentions, thoughts, etc.) to self and to others, allowing an individual to understand and infer behavior on the basis of the mental states. Difference or deficit in theory of mind is associated with ASPERGER SYNDROME; AUTISTIC DISORDER; and SCHIZOPHRENIA, etc.
Any behavior caused by or affecting another individual, usually of the same species.
The perceiving of attributes, characteristics, and behaviors of one's associates or social groups.
A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.
An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Learning the correct route through a maze to obtain reinforcement. It is used for human or animal populations. (Thesaurus of Psychological Index Terms, 6th ed)
Study of mental processes and behavior of schizophrenics.
Remembrance of information for a few seconds to hours.
Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.
Capacity that enables an individual to cope with and/or recover from the impact of a neural injury or a psychotic episode.
Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
The feeling-tone accompaniment of an idea or mental representation. It is the most direct psychic derivative of instinct and the psychic representative of the various bodily changes by means of which instincts manifest themselves.
The coordination of a sensory or ideational (cognitive) process and a motor activity.
The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions.
Those affective states which can be experienced and have arousing and motivational properties.
Standardized tests that measure the present general ability or aptitude for intellectual performance.
A prodromal phase of cognitive decline that may precede the emergence of ALZHEIMER DISEASE and other dementias. It may include impairment of cognition, such as impairments in language, visuospatial awareness, ATTENTION and MEMORY.
Modifying, carrying, or manipulating an item external to itself by an animal, before using it to effect a change on the environment or itself (from Beck, Animal Tool Behavior, 1980).
The ability to understand and manage emotions and to use emotional knowledge to enhance thought and deal effectively with tasks. Components of emotional intelligence include empathy, self-motivation, self-awareness, self-regulation, and social skill. Emotional intelligence is a measurement of one's ability to socialize or relate to others.
Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge.
Standardized clinical interview used to assess current psychopathology by scaling patient responses to the questions.
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. The prefrontal cortex receives afferent fibers from numerous structures of the DIENCEPHALON; MESENCEPHALON; and LIMBIC SYSTEM as well as cortical afferents of visual, auditory, and somatic origin.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
A learning situation involving more than one alternative from which a selection is made in order to attain a specific goal.
A psychological theory based on dimensions or categories used by a given person in describing or explaining the personality and behavior of others or of himself. The basic idea is that different people will use consistently different categories. The theory was formulated in the fifties by George Kelly. Two tests devised by him are the role construct repertory test and the repertory grid test. (From Stuart Sutherland, The International Dictionary of Psychology, 1989)
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
Reactions of an individual or groups of individuals with relation to the immediate surrounding area including the animate or inanimate objects within that area.
The time from the onset of a stimulus until a response is observed.
The scientific disciplines concerned with the embryology, anatomy, physiology, biochemistry, pharmacology, etc., of the nervous system.
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
The observable response of a man or animal to a situation.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Learning to respond verbally to a verbal stimulus cue.
The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE.
Theoretical representations that simulate psychological processes and/or social processes. These include the use of mathematical equations, computers, and other electronic equipment.
A verbal or nonverbal means of communicating ideas or feelings.
A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.
Conceptual functions or thinking in all its forms.
Common name for the largest birds in the order PASSERIFORMES, family Corvidae. These omnivorous black birds comprise most of the species in the genus Corvus, along with ravens and jackdaws (which are often also referred to as crows).
Assessment of psychological variables by the application of mathematical procedures.
The awareness of the spatial properties of objects; includes physical space.
A meshlike structure composed of interconnecting nerve cells that are separated at the synaptic junction or joined to one another by cytoplasmic processes. In invertebrates, for example, the nerve net allows nerve impulses to spread over a wide area of the net because synapses can pass information in any direction.
The knowledge or perception that someone or something present has been previously encountered.
The study of the precise nature of different mental tasks and the operations of the brain that enable them to be performed, engaging branches of psychology, computer science, philosophy, and linguistics. (Random House Unabridged Dictionary, 2d ed)
A functional relationship between psychological phenomena of such nature that the presence of one tends to evoke the other; also, the process by which such a relationship is established.
The observable response an animal makes to any situation.
Standardized tests designed to measure abilities, as in intelligence, aptitude, and achievement tests, or to evaluate personality traits.
Mental activity, not predominantly perceptual, by which one apprehends some aspect of an object or situation based on past learning and experience.
An individual's objective and insightful awareness of the feelings and behavior of another person. It should be distinguished from sympathy, which is usually nonobjective and noncritical. It includes caring, which is the demonstration of an awareness of and a concern for the good of others. (From Bioethics Thesaurus, 1992)
A component of the NATIONAL INSTITUTES OF HEALTH concerned with research, overall planning, promoting, and administering mental health programs and research. It was established in 1949.
The process of discovering or asserting an objective or intrinsic relation between two objects or concepts; a faculty or power that enables a person to make judgments; the process of bringing to light and asserting the implicit meaning of a concept; a critical evaluation of a person or situation.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
The selecting and organizing of visual stimuli based on the individual's past experience.
The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.
Aryl CYCLOPENTANES that are a reduced (protonated) form of INDENES.
The detailed examination of observable activity or behavior associated with the execution or completion of a required function or unit of work.
A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.
Includes both producing and responding to words, either written or spoken.
The process whereby a representation of past experience is elicited.
An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
The performance of the basic activities of self care, such as dressing, ambulation, or eating.
Evaluation of the level of physical, physiological, or mental functioning in the older population group.
Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
Those psychological characteristics which differentiate individuals from one another.
Neural tracts connecting one part of the nervous system with another.
Principles applied to the analysis and explanation of psychological or behavioral phenomena.
Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a catecholamine.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
Tests designed to measure intellectual functioning in children and adults.
Observable changes of expression in the face in response to emotional stimuli.
The reciprocal interaction of two or more persons.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Non-invasive methods of visualizing the CENTRAL NERVOUS SYSTEM, especially the brain, by various imaging modalities.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
The tendency to explore or investigate a novel environment. It is considered a motivation not clearly distinguishable from curiosity.
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
A cognitive process involving the formation of ideas generalized from the knowledge of qualities, aspects, and relations of objects.
Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
The science and art of collecting, summarizing, and analyzing data that are subject to random variation. The term is also applied to the data themselves and to the summarization of the data.
Behaviors which are at variance with the expected social norm and which affect other individuals.
Adaptation of the person to the social environment. Adjustment may take place by adapting the self to the environment or by changing the environment. (From Campbell, Psychiatric Dictionary, 1996)
The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.
A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.
The physical activity of a human or an animal as a behavioral phenomenon.
A direct form of psychotherapy based on the interpretation of situations (cognitive structure of experiences) that determine how an individual feels and behaves. It is based on the premise that cognition, the process of acquiring knowledge and forming beliefs, is a primary determinant of mood and behavior. The therapy uses behavioral and verbal techniques to identify and correct negative thinking that is at the root of the aberrant behavior.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A collective expression for all behavior patterns acquired and socially transmitted through symbols. Culture includes customs, traditions, and language.
A chronic form of schizophrenia characterized primarily by the presence of persecutory or grandiose delusions, often associated with hallucination.
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
The act of "taking account" of an object or state of affairs. It does not imply assessment of, nor attention to the qualities or nature of the object.
Elements of limited time intervals, contributing to particular results or situations.
The subject's ability to connect 25 numbered and lettered circles in sequence in a specific length of time. A score of 12 or below is suggestive of organic brain damage.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Educational attainment or level of education of individuals.
Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.
What a person has in mind to do or bring about.
Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These disorders may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
The use of technology-based interventions to improve functional capacities rather than to treat disease.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
A scale comprising 18 symptom constructs chosen to represent relatively independent dimensions of manifest psychopathology. The initial intended use was to provide more efficient assessment of treatment response in clinical psychopharmacology research; however, the scale was readily adapted to other uses. (From Hersen, M. and Bellack, A.S., Dictionary of Behavioral Assessment Techniques, p. 87)
A person's view of himself.
Observable manifestations of impaired psychological functioning.
Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.
Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.
A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.
Those factors which cause an organism to behave or act in either a goal-seeking or satisfying manner. They may be influenced by physiological drives or by external stimuli.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Those disorders that have a disturbance in mood as their predominant feature.
Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs.
The process by which the nature and meaning of sensory stimuli are recognized and interpreted.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Methods for visualizing REGIONAL BLOOD FLOW, metabolic, electrical, or other physiological activities in the CENTRAL NERVOUS SYSTEM using various imaging modalities.
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.
A housing and community arrangement that maximizes independence and self-determination.
Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.
A state of harmony between internal needs and external demands and the processes used in achieving this condition. (From APA Thesaurus of Psychological Index Terms, 8th ed)
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
The continuous developmental process of a culture from simple to complex forms and from homogeneous to heterogeneous qualities.
Signals for an action; that specific portion of a perceptual field or pattern of stimuli to which a subject has learned to respond.
Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The affective response to an actual current external danger which subsides with the elimination of the threatening condition.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Drugs that selectively bind to but do not activate HISTAMINE H3 RECEPTORS. They have been used to correct SLEEP WAKE DISORDERS and MEMORY DISORDERS.
The interference with or prevention of a behavioral or verbal response even though the stimulus for that response is present; in psychoanalysis the unconscious restraining of an instinctual process.
The sum or the stock of words used by a language, a group, or an individual. (From Webster, 3d ed)
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.
Performance of complex motor acts.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
The mimicking of the behavior of one individual by another.
Phenyl esters of carbamic acid or of N-substituted carbamic acids. Structures are similar to PHENYLUREA COMPOUNDS with a carbamate in place of the urea.
The discipline pertaining to the study of animal behavior.
The ability of the BRAIN to suppress neuronal responses to external sensory inputs, such as auditory and visual stimuli. Sensory filtering (or gating) allows humans to block out irrelevant, meaningless, or redundant stimuli.
Marked impairments in the development of motor coordination such that the impairment interferes with activities of daily living. (From DSM-V)
The act or fact of grasping the meaning, nature, or importance of; understanding. (American Heritage Dictionary, 4th ed) Includes understanding by a patient or research subject of information disclosed orally or in writing.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Conditions characterized by deficiencies of comprehension or expression of written and spoken forms of language. These include acquired and developmental disorders.
A response to a cue that is instrumental in avoiding a noxious experience.
Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.
Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
Transmission of emotions, ideas, and attitudes between individuals in ways other than the spoken language.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
The conscious portion of the personality structure which serves to mediate between the demands of the primitive instinctual drives, (the id), of internalized parental and social prohibitions or the conscience, (the superego), and of reality.
Accumulations of extracellularly deposited AMYLOID FIBRILS within tissues.
Numeric or quantitative entities, descriptions, properties, relationships, operations, and events.
The state that distinguishes organisms from inorganic matter, manifested by growth, metabolism, reproduction, and adaptation. It includes the course of existence, the sum of experiences, the mode of existing, or the fact of being. Over the centuries inquiries into the nature of life have crossed the boundaries from philosophy to biology, forensic medicine, anthropology, etc., in creative as well as scientific literature. (Random House Unabridged Dictionary, 2d ed; Dr. James H. Cassedy, NLM History of Medicine Division)
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
The principle that items experienced together enter into a connection, so that one tends to reinstate the other.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.
The relationships between symbols and their meanings.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
The gradual expansion in complexity and meaning of symbols and sounds as perceived and interpreted by the individual through a maturational and learning process. Stages in development include babbling, cooing, word imitation with cognition, and use of short sentences.
The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.
Wave-like oscillations of electric potential between parts of the brain recorded by EEG.
Any situation where an animal or human is trained to respond differentially to two stimuli (e.g., approach and avoidance) under reward and punishment conditions and subsequently trained under reversed reward values (i.e., the approach which was previously rewarded is punished and vice versa).
A false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one's associates.
Research that involves the application of the behavioral and social sciences to the study of the actions or reactions of persons or animals in response to external or internal stimuli. (from American Heritage Dictionary, 4th ed)
The individual's objective evaluation of the external world and the ability to differentiate adequately between it and the internal world; considered to be a primary ego function.
The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community.
Clinical or physiological indicators that precede the onset of disease.
The ability to generate new ideas or images.
Cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs. These include spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body.
Any observable response or action of a child from 24 months through 12 years of age. For neonates or children younger than 24 months, INFANT BEHAVIOR is available.
Stress wherein emotional factors predominate.
One of the convolutions on the medial surface of the CEREBRAL HEMISPHERES. It surrounds the rostral part of the brain and CORPUS CALLOSUM and forms part of the LIMBIC SYSTEM.
The pygmy chimpanzee, a species of the genus Pan, family HOMINIDAE. Its common name is Bonobo, which was once considered a separate genus by some; others considered it a subspecies of PAN TROGLODYTES. Its range is confined to the forests of the central Zaire basin. Despite its name, it is often of equal size to P. troglodytes.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
A branch of psychology which investigates the correlation between experience or behavior and the basic neurophysiological processes. The term neuropsychology stresses the dominant role of the nervous system. It is a more narrowly defined field than physiological psychology or psychophysiology.
The branch of psychology concerned with similarities or differences in the behavior of different animal species or of different races or peoples.
Agents that improve the ability to carry out activities such as athletics, mental endurance, work, and resistance to stress. The substances can include PRESCRIPTION DRUGS; DIETARY SUPPLEMENTS; phytochemicals; and ILLICIT DRUGS.
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
A family of hexahydropyridines.
Remembrance of information from 3 or more years previously.
The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.
An object or a situation that can serve to reinforce a response, to satisfy a motive, or to afford pleasure.
Pathological processes or diseases where cerebral MICROVESSELS show abnormalities. They are often associated with aging, hypertension and risk factors for lacunar infarcts (see LACUNAR INFARCTION); LEUKOARAIOSIS; and CEREBRAL HEMORRHAGE.
Family of the suborder HAPLORHINI (Anthropoidea) comprising bipedal primate MAMMALS. It includes modern man (HOMO SAPIENS) and the great apes: gorillas (GORILLA GORILLA), chimpanzees (PAN PANISCUS and PAN TROGLODYTES), and orangutans (PONGO PYGMAEUS).
Differential response to different stimuli.

Frontal cognitive impairments and saccadic deficits in low-dose MPTP-treated monkeys. (1/9619)

There is considerable overlap between the cognitive deficits observed in humans with frontal lobe damage and those described in patients with Parkinson's disease. Similar frontal impairments have been found in the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) primate model of Parkinsonism. Here we provide quantitative documentation of the cognitive, oculomotor, and skeletomotor dysfunctions of monkeys trained on a frontal task and treated with low-doses (LD) of MPTP. Two rhesus monkeys were trained to perform a spatial delayed-response task with frequent alternations between two behavioral modes (GO and NO-GO). After control recordings, the monkeys were treated with one placebo and successive LD MPTP courses. Monkey C developed motor Parkinsonian signs after a fourth course of medium-dose (MD) MPTP and later was treated with combined dopaminergic therapy (CDoT). There were no gross motor changes after the LD MPTP courses, and the average movement time (MT) did not increase. However, reaction time (RT) increased significantly. Both RT and MT were further increased in the symptomatic state, under CDoT. Self-initiated saccades became hypometric after LD MPTP treatments and their frequency decreased. Visually triggered saccades were affected to a lesser extent by the LD MPTP treatments. All saccadic parameters declined further in the symptomatic state and improved partially during CDoT. The number of GO mode (no-response, location, and early release) errors increased after MPTP treatment. The monkeys made more perseverative errors while switching from the GO to the NO-GO mode. Saccadic eye movement patterns suggest that frontal deficits were involved in most observed errors. CDoT had a differential effect on the behavioral errors. It decreased omission errors but did not improve location errors or perseverative errors. Tyrosine hydroxylase immunohistochemistry showed moderate ( approximately 70-80%) reduction in the number of dopaminergic neurons in the substantia nigra pars compacta after MPTP treatment. These results show that cognitive and motor disorders can be dissociated in the LD MPTP model and that cognitive and oculomotor impairments develop before the onset of skeletal motor symptoms. The behavioral and saccadic deficits probably result from the marked reduction of dopaminergic neurons in the midbrain. We suggest that these behavioral changes result from modified neuronal activity in the frontal cortex.  (+info)

Non-motor associative learning in patients with isolated degenerative cerebellar disease. (2/9619)

In recent decades it has become clear that the cerebellum is involved in associative motor learning, but its exact role in motor learning as such is still controversial. Recently, a contribution of the cerebellum to different cognitive abilities has also been considered, but it remains unclear whether the cerebellum contributes to cognitive associative learning. We compared nine patients with an isolated cerebellar degenerative disease in a cognitive associative learning task with 10 controls. Patients and controls were matched for age, sex, handedness, level of education, intelligence and capabilities of visual memory. The subjects were asked to learn the association between six pairs of colours and numerals by trial and error. Additionally, a simple reaction time and a visual scanning test were conducted in order to control for the influence of motor performance deficits in cerebellar patients. In comparison with the controls, it took the patients significantly longer to learn the correct associations between colours and numerals, and they were impaired in recognizing them later on. Two patients showed no associative learning effect at all. Neither the simple reaction time nor the visual scanning time correlated substantially with the results of associative learning. Therefore, motor-associated disabilities are unlikely to be the reason for the learning deficit in cerebellar patients. Our results suggest that the cerebellum might contribute to motor-independent processes that are generally involved in associative learning.  (+info)

The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia. (3/9619)

Administration of noncompetitive NMDA/glutamate receptor antagonists, such as phencyclidine (PCP) and ketamine, to humans induces a broad range of schizophrenic-like symptomatology, findings that have contributed to a hypoglutamatergic hypothesis of schizophrenia. Moreover, a history of experimental investigations of the effects of these drugs in animals suggests that NMDA receptor antagonists may model some behavioral symptoms of schizophrenia in nonhuman subjects. In this review, the usefulness of PCP administration as a potential animal model of schizophrenia is considered. To support the contention that NMDA receptor antagonist administration represents a viable model of schizophrenia, the behavioral and neurobiological effects of these drugs are discussed, especially with regard to differing profiles following single-dose and long-term exposure. The neurochemical effects of NMDA receptor antagonist administration are argued to support a neurobiological hypothesis of schizophrenia, which includes pathophysiology within several neurotransmitter systems, manifested in behavioral pathology. Future directions for the application of NMDA receptor antagonist models of schizophrenia to preclinical and pathophysiological research are offered.  (+info)

Effect of iron-, iodine-, and beta-carotene-fortified biscuits on the micronutrient status of primary school children: a randomized controlled trial. (4/9619)

BACKGROUND: Deficiencies of iron, iodine, and vitamin A are prevalent worldwide and can affect the mental development and learning ability of schoolchildren. OBJECTIVE: The aim of this study was to determine the effect of micronutrient-fortified biscuits on the micronutrient status of primary school children. DESIGN: Micronutrient status was assessed in 115 children aged 6-11 y before and after consumption of biscuits (fortified with iron, iodine, and beta-carotene) for 43 wk over a 12-mo period and was compared with that in a control group (n = 113) who consumed nonfortified biscuits. Cognitive function, growth, and morbidity were assessed as secondary outcomes. RESULTS: There was a significant between-group treatment effect on serum retinol, serum ferritin, serum iron, transferrin saturation, and urinary iodine (P <0.0001) and in hemoglobin and hematocrit (P <0.05). The prevalence of low serum retinol concentrations (<0.70 micromol/L) decreased from 39.1% to 12.2%, of low serum ferritin concentrations (<20 microg/L) from 27.8% to 13.9%, of anemia (hemoglobin <120 g/L) from 29.6% to 15.6%, and of low urinary iodine concentrations (<100 microg/L) from 97.5% to 5.4%. There was a significant between-group treatment effect (P <0.05) in cognitive function with the digit span forward task (short-term memory). Fewer school days were missed in the intervention than in the control group because of respiratory- (P = 0.097) and diarrhea-related (P = 0.013) illnesses. The intervention had no effect on anthropometric status [corrected]. CONCLUSIONS: Fortified biscuits resulted in a significant improvement in the micronutrient status of primary school children from a poor rural community and also appeared to have a favorable effect on morbidity and cognitive function [corrected].  (+info)

Cognitive outcome after unilateral pallidal stimulation in Parkinson's disease. (5/9619)

OBJECTIVES: Chronic high frequency electrostimulation of the globus pallidus internus mimics pallidotomy and improves clinical symptoms in Parkinson's disease. The aim of this study was to investigate the cognitive consequences of unilateral deep brain stimulation. METHODS: Twenty non-demented patients with Parkinson's disease (age range 38-70 years) were neuropsychologically assessed 2 months before and 3 months after unilateral pallidal stimulation. The cognitive assessment included measures of memory, spatial behaviour, and executive and psychomotor function. In addition to group analysis of cognitive change, a cognitive impairment index (CII) was calculated for each individual patient representing the percentage of cognitive measures that fell more than 1 SD below the mean of a corresponding normative sample. RESULTS: Neurological assessment with the Hoehn and Yahr scale and the unified Parkinson's disease rating scale disclosed a significant postoperative reduction in average clinical Parkinson's disease symptomatology (p<0.001). Repeated measures multivariate analysis of variance (using right/left side of stimulation as a between subjects factor) showed no significant postoperative change in cognitive performance for the total patient group (main effect of operation). The side of stimulation did not show a significant differential effect on cognitive performance (main effect of lateralisation). There was no significant operation by lateralisation interaction effect. Although the patients experienced significant motor symptom relief after pallidal stimulation, they remained mildly depressed after surgery. Analysis of the individual CII changes showed a postoperative cognitive decline in 30% of the patients. These patients were significantly older and took higher preoperative doses of levodopa than patients showing no change or a postoperative cognitive improvement. CONCLUSIONS: Left or right pallidal stimulation for the relief of motor symptoms in Parkinson's disease seems relatively safe, although older patients and patients needing high preoperative doses of levodopa seem to be more vulnerable for cognitive decline after deep brain stimulation.  (+info)

Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms. (6/9619)

We used a novel computerized decision-making task to compare the decision-making behavior of chronic amphetamine abusers, chronic opiate abusers, and patients with focal lesions of orbital prefrontal cortex (PFC) or dorsolateral/medial PFC. We also assessed the effects of reducing central 5-hydroxytryptamine (5-HT) activity using a tryptophan-depleting amino acid drink in normal volunteers. Chronic amphetamine abusers showed suboptimal decisions (correlated with years of abuse), and deliberated for significantly longer before making their choices. The opiate abusers exhibited only the second of these behavioral changes. Importantly, both sub-optimal choices and increased deliberation times were evident in the patients with damage to orbitofrontal PFC but not other sectors of PFC. Qualitatively, the performance of the subjects with lowered plasma tryptophan was similar to that associated with amphetamine abuse, consistent with recent reports of depleted 5-HT in the orbital regions of PFC of methamphetamine abusers. Overall, these data suggest that chronic amphetamine abusers show similar decision-making deficits to those seen after focal damage to orbitofrontal PFC. These deficits may reflect altered neuromodulation of the orbitofrontal PFC and interconnected limbic-striatal systems by both the ascending 5-HT and mesocortical dopamine (DA) projections.  (+info)

The neural consequences of conflict between intention and the senses. (7/9619)

Normal sensorimotor states involve integration of intention, action and sensory feedback. An example is the congruence between motor intention and sensory experience (both proprioceptive and visual) when we move a limb through space. Such goal-directed action necessitates a mechanism that monitors sensorimotor inputs to ensure that motor outputs are congruent with current intentions. Monitoring in this sense is usually implicit and automatic but becomes conscious whenever there is a mismatch between expected and realized sensorimotor states. To investigate how the latter type of monitoring is achieved we conducted three fully factorial functional neuroimaging experiments using PET measures of relative regional cerebral blood flow with healthy volunteers. In the first experiment subjects were asked to perform Luria's bimanual co-ordination task which involves either in-phase (conditions 1 and 3) or out-of-phase (conditions 2 and 4) bimanual movements (factor one), while looking towards their left hand. In half of the conditions (conditions 3 and 4) a mirror was used that altered visual feedback (factor two) by replacing their left hand with the mirror image of their right hand. Hence (in the critical condition 4) subjects saw in-phase movements despite performing out-of-phase movements. This mismatch between intention, proprioception and visual feedback engendered cognitive conflict. The main effect of out-of-phase movements was associated with increased neural activity in posterior parietal cortex (PPC) bilaterally [Brodmann area (BA) 40, extending into BA 7] and dorsolateral prefrontal cortex (DLPFC) bilaterally (BA 9/46). The main effect of the mirror showed increased neural activity in right DLPFC (BA 9/ 46) and right superior PPC (BA 7) only. Analysis of the critical interaction revealed that the mismatch condition led to a specific activation in the right DLPFC alone (BA 9/46). Study 2, using an identical experimental set-up but manipulating visual feedback from the right hand (instead of the left), subsequently demonstrated that this right DLPFC activation was independent of the hand attended. Finally, study 3 removed the motor intentional component by moving the subjects' hand passively, thus engendering a mismatch between proprioception and vision only. Activation in the right lateral prefrontal cortex was now more ventral than in studies 1 or 2 (BA 44/45). A direct comparison of studies 1 and 3 (which both manipulated visual feedback from the left hand) confirmed that a ventral right lateral prefrontal region is primarily activated by discrepancies between signals from sensory systems, while a more dorsal area in right lateral prefrontal cortex is activated when actions must be maintained in the face of a conflict between intention and sensory outcome.  (+info)

Optical imaging of functional domains in the cortex of the awake and behaving monkey. (8/9619)

As demonstrated by anatomical and physiological studies, the cerebral cortex consists of groups of cortical modules, each comprising populations of neurons with similar functional properties. This functional modularity exists in both sensory and association neocortices. However, the role of such cortical modules in perceptual and cognitive behavior is unknown. To aid in the examination of this issue we have applied the high spatial resolution optical imaging methodology to the study of awake, behaving animals. In this paper, we report the optical imaging of orientation domains and blob structures, approximately 100-200 micrometer in size, in visual cortex of the awake and behaving monkey. By overcoming the spatial limitations of other existing imaging methods, optical imaging will permit the study of a wide variety of cortical functions at the columnar level, including motor and cognitive functions traditionally studied with positron-emission tomography or functional MRI techniques.  (+info)

Types of Cognition Disorders: There are several types of cognitive disorders that affect different aspects of cognitive functioning. Some common types include:

1. Attention Deficit Hyperactivity Disorder (ADHD): Characterized by symptoms of inattention, hyperactivity, and impulsivity.
2. Traumatic Brain Injury (TBI): Caused by a blow or jolt to the head that disrupts brain function, resulting in cognitive, emotional, and behavioral changes.
3. Alzheimer's Disease: A progressive neurodegenerative disorder characterized by memory loss, confusion, and difficulty with communication.
4. Stroke: A condition where blood flow to the brain is interrupted, leading to cognitive impairment and other symptoms.
5. Parkinson's Disease: A neurodegenerative disorder that affects movement, balance, and cognition.
6. Huntington's Disease: An inherited disorder that causes progressive damage to the brain, leading to cognitive decline and other symptoms.
7. Frontotemporal Dementia (FTD): A group of neurodegenerative disorders characterized by changes in personality, behavior, and language.
8. Post-Traumatic Stress Disorder (PTSD): A condition that develops after a traumatic event, characterized by symptoms such as anxiety, avoidance, and hypervigilance.
9. Mild Cognitive Impairment (MCI): A condition characterized by memory loss and other cognitive symptoms that are more severe than normal age-related changes but not severe enough to interfere with daily life.

Causes and Risk Factors: The causes of cognition disorders can vary depending on the specific disorder, but some common risk factors include:

1. Genetics: Many cognitive disorders have a genetic component, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.
2. Age: As people age, their risk of developing cognitive disorders increases, such as Alzheimer's disease, vascular dementia, and frontotemporal dementia.
3. Lifestyle factors: Factors such as physical inactivity, smoking, and poor diet can increase the risk of cognitive decline and dementia.
4. Traumatic brain injury: A severe blow to the head or a traumatic brain injury can increase the risk of developing cognitive disorders, such as chronic traumatic encephalopathy (CTE).
5. Infections: Certain infections, such as meningitis and encephalitis, can cause cognitive disorders if they damage the brain tissue.
6. Stroke or other cardiovascular conditions: A stroke or other cardiovascular conditions can cause cognitive disorders by damaging the blood vessels in the brain.
7. Chronic substance abuse: Long-term use of drugs or alcohol can damage the brain and increase the risk of cognitive disorders, such as dementia.
8. Sleep disorders: Sleep disorders, such as sleep apnea, can increase the risk of cognitive disorders, such as dementia.
9. Depression and anxiety: Mental health conditions, such as depression and anxiety, can increase the risk of cognitive decline and dementia.
10. Environmental factors: Exposure to certain environmental toxins, such as pesticides and heavy metals, has been linked to an increased risk of cognitive disorders.

It's important to note that not everyone with these risk factors will develop a cognitive disorder, and some people without any known risk factors can still develop a cognitive disorder. If you have concerns about your cognitive health, it's important to speak with a healthcare professional for proper evaluation and diagnosis.

The term "schizophrenia" was first used by the Swiss psychiatrist Eugen Bleuler in 1908 to describe the splitting of mental functions, which he believed was a key feature of the disorder. The word is derived from the Greek words "schizein," meaning "to split," and "phrenos," meaning "mind."

There are several subtypes of schizophrenia, including:

1. Paranoid Schizophrenia: Characterized by delusions of persecution and suspicion, and a tendency to be hostile and defensive.
2. Hallucinatory Schizophrenia: Characterized by hearing voices or seeing things that are not there.
3. Disorganized Schizophrenia: Characterized by disorganized thinking and behavior, and a lack of motivation or interest in activities.
4. Catatonic Schizophrenia: Characterized by immobility, mutism, and other unusual movements or postures.
5. Undifferentiated Schizophrenia: Characterized by a combination of symptoms from the above subtypes.

The exact cause of schizophrenia is still not fully understood, but it is believed to involve a combination of genetic, environmental, and neurochemical factors. It is important to note that schizophrenia is not caused by poor parenting or a person's upbringing.

There are several risk factors for developing schizophrenia, including:

1. Genetics: A person with a family history of schizophrenia is more likely to develop the disorder.
2. Brain chemistry: Imbalances in neurotransmitters such as dopamine and serotonin have been linked to schizophrenia.
3. Prenatal factors: Factors such as maternal malnutrition or exposure to certain viruses during pregnancy may increase the risk of schizophrenia in offspring.
4. Childhood trauma: Traumatic events during childhood, such as abuse or neglect, have been linked to an increased risk of developing schizophrenia.
5. Substance use: Substance use has been linked to an increased risk of developing schizophrenia, particularly cannabis and other psychotic substances.

There is no cure for schizophrenia, but treatment can help manage symptoms and improve quality of life. Treatment options include:

1. Medications: Antipsychotic medications are the primary treatment for schizophrenia. They can help reduce positive symptoms such as hallucinations and delusions, and negative symptoms such as a lack of motivation or interest in activities.
2. Therapy: Cognitive-behavioral therapy (CBT) and other forms of talk therapy can help individuals with schizophrenia manage their symptoms and improve their quality of life.
3. Social support: Support from family, friends, and support groups can be an important part of the treatment plan for individuals with schizophrenia.
4. Self-care: Engaging in activities that bring pleasure and fulfillment, such as hobbies or exercise, can help individuals with schizophrenia improve their overall well-being.

It is important to note that schizophrenia is a complex condition, and treatment should be tailored to the individual's specific needs and circumstances. With appropriate treatment and support, many people with schizophrenia are able to lead fulfilling lives and achieve their goals.

There are several types of dementia, each with its own set of symptoms and characteristics. Some common types of dementia include:

* Alzheimer's disease: This is the most common form of dementia, accounting for 50-70% of all cases. It is a progressive disease that causes the death of brain cells, leading to memory loss and cognitive decline.
* Vascular dementia: This type of dementia is caused by problems with blood flow to the brain, often as a result of a stroke or small vessel disease. It can cause difficulty with communication, language, and visual-spatial skills.
* Lewy body dementia: This type of dementia is characterized by the presence of abnormal protein deposits called Lewy bodies in the brain. It can cause a range of symptoms, including memory loss, confusion, hallucinations, and difficulty with movement.
* Frontotemporal dementia: This is a group of diseases that affect the front and temporal lobes of the brain, leading to changes in personality, behavior, and language.

The symptoms of dementia can vary depending on the underlying cause, but common symptoms include:

* Memory loss: Difficulty remembering recent events or learning new information.
* Communication and language difficulties: Struggling to find the right words or understand what others are saying.
* Disorientation: Getting lost in familiar places or having difficulty understanding the time and date.
* Difficulty with problem-solving: Trouble with planning, organizing, and decision-making.
* Mood changes: Depression, anxiety, agitation, or aggression.
* Personality changes: Becoming passive, suspicious, or withdrawn.
* Difficulty with movement: Trouble with coordination, balance, or using utensils.
* Hallucinations: Seeing or hearing things that are not there.
* Sleep disturbances: Having trouble falling asleep or staying asleep.

The symptoms of dementia can be subtle at first and may progress slowly over time. In the early stages, they may be barely noticeable, but as the disease progresses, they can become more pronounced and interfere with daily life. It is important to seek medical advice if you or a loved one is experiencing any of these symptoms, as early diagnosis and treatment can help improve outcomes.

The symptoms of Alzheimer's disease can vary from person to person and may progress slowly over time. Early symptoms may include memory loss, confusion, and difficulty with problem-solving. As the disease progresses, individuals may experience language difficulties, visual hallucinations, and changes in mood and behavior.

There is currently no cure for Alzheimer's disease, but there are several medications and therapies that can help manage its symptoms and slow its progression. These include cholinesterase inhibitors, memantine, and non-pharmacological interventions such as cognitive training and behavioral therapy.

Alzheimer's disease is a significant public health concern, affecting an estimated 5.8 million Americans in 2020. It is the sixth leading cause of death in the United States, and its prevalence is expected to continue to increase as the population ages.

There is ongoing research into the causes and potential treatments for Alzheimer's disease, including studies into the role of inflammation, oxidative stress, and the immune system. Other areas of research include the development of biomarkers for early detection and the use of advanced imaging techniques to monitor progression of the disease.

Overall, Alzheimer's disease is a complex and multifactorial disorder that poses significant challenges for individuals, families, and healthcare systems. However, with ongoing research and advances in medical technology, there is hope for improving diagnosis and treatment options in the future.

Some common types of memory disorders include:

1. Amnesia: A condition where an individual experiences memory loss, either partial or total, due to brain damage or other causes.
2. Dementia: A broad term that describes a decline in cognitive function, including memory loss, confusion, and difficulty with communication and daily activities. Alzheimer's disease is the most common cause of dementia.
3. Mild Cognitive Impairment (MCI): A condition characterized by memory loss and other cognitive symptoms that are more severe than normal age-related changes but not as severe as dementia.
4. Attention Deficit Hyperactivity Disorder (ADHD): A neurodevelopmental disorder that affects attention, impulse control, and hyperactivity. Memory problems are often a component of ADHD.
5. Traumatic Brain Injury (TBI): A condition that occurs when the brain is injured due to a blow or jolt to the head, which can result in memory loss and other cognitive problems.
6. Stroke: A condition where blood flow to the brain is interrupted, leading to brain cell death and potential memory loss.
7. Meningitis: An inflammatory condition that affects the membranes covering the brain and spinal cord, which can lead to memory loss and other cognitive problems.
8. Encephalitis: An inflammatory condition that affects the brain directly, leading to memory loss and other cognitive problems.
9. Chronic Fatigue Syndrome (CFS): A condition characterized by persistent fatigue, memory loss, and other cognitive symptoms.
10. Sleep Disorders: Sleep disturbances can affect memory and cognitive function, including conditions such as insomnia, sleep apnea, and restless leg syndrome.

The diagnosis of memory disorders typically involves a combination of medical history, physical examination, laboratory tests, and neuropsychological evaluations. The specific treatment approach will depend on the underlying cause of the memory loss, but may include medication, behavioral interventions, and lifestyle changes.

The diagnosis of MCI requires a comprehensive medical evaluation, including a thorough history, physical examination, laboratory tests, and cognitive assessments. The goal of the diagnosis is to differentiate MCI from normal aging and other conditions that may cause similar symptoms, such as depression or medication side effects.

There are several subtypes of MCI, including:

1. Amnestic Mild Cognitive Impairment (aMCI): Characterized by memory loss, especially for episodic memory (memory of events and experiences).
2. Non-amnestic Mild Cognitive Impairment (naMCI): Characterized by cognitive impairment without memory loss.
3. Mixed Mild Cognitive Impairment (mMCI): Characterized by a combination of amnestic and non-amnestic symptoms.

The main risk factor for developing MCI is advancing age, but other factors such as family history, genetics, and lifestyle factors may also contribute to the development of the condition. There is currently no cure for MCI, but there are several treatment options available to slow down cognitive decline and improve quality of life. These include:

1. Cognitive training and rehabilitation: To improve memory, attention, and other cognitive functions.
2. Medications: Such as cholinesterase inhibitors, which can improve cognitive function and slow down decline.
3. Lifestyle changes: Such as regular exercise, social engagement, and management of chronic health conditions.
4. Alternative therapies: Such as cognitive training, mindfulness-based interventions, and herbal supplements.

Early detection and treatment of MCI can potentially delay progression to dementia, improve quality of life, and reduce caregiver burden. However, the exact timing and duration of these benefits are not yet fully understood. Further research is needed to understand the mechanisms underlying MCI and to develop more effective treatments for this condition.

In summary, mild cognitive impairment (MCI) is a condition characterized by cognitive decline beyond what is expected for an individual's age and education level, but not severe enough to interfere with daily life. There are three subtypes of MCI, and the main risk factor is advancing age. Treatment options include cognitive training and rehabilitation, medications, lifestyle changes, and alternative therapies. Early detection and treatment may potentially delay progression to dementia and improve quality of life.

The symptoms of vascular dementia can vary depending on the location and severity of the damage to the brain, but common symptoms include:

* Memory loss, such as difficulty remembering recent events or learning new information
* Confusion and disorientation
* Difficulty with communication, including trouble finding the right words or understanding what others are saying
* Difficulty with problem-solving, decision-making, and judgment
* Mood changes, such as depression, anxiety, or agitation
* Personality changes, such as becoming more passive or suspicious
* Difficulty with coordination and movement, including trouble walking or balance

Vascular dementia can be caused by a variety of conditions that affect the blood vessels in the brain, including:

* Stroke or transient ischemic attack (TIA, or "mini-stroke")
* Small vessel disease, such as tiny strokes or changes in the blood vessels that occur over time
* Moyamoya disease, a rare condition caused by narrowing or blockage of the internal carotid artery and its branches
* Cerebral amyloid angiopathy, a condition in which abnormal protein deposits build up in the blood vessels of the brain
* Other conditions that can cause reduced blood flow to the brain, such as high blood pressure, diabetes, or cardiovascular disease

There is no cure for vascular dementia, but there are several treatment options available to help manage its symptoms and slow its progression. These may include medications to improve memory and cognitive function, physical therapy to maintain mobility and strength, and lifestyle changes such as a healthy diet and regular exercise. In some cases, surgery or endovascular procedures may be recommended to treat the underlying cause of the dementia, such as a stroke or blocked blood vessel.

It is important for individuals with vascular dementia to receive timely and accurate diagnosis and treatment, as well as ongoing support and care from healthcare professionals, family members, and caregivers. With appropriate management, many people with vascular dementia are able to maintain their independence and quality of life for as long as possible.

Some common types of psychotic disorders include:

1. Schizophrenia: A chronic and severe mental disorder that affects how a person thinks, feels, and behaves. It can cause hallucinations, delusions, and disorganized thinking.
2. Bipolar Disorder: A mood disorder that causes extreme changes in mood, energy, and behavior. It can lead to manic or hypomanic episodes, as well as depression.
3. Schizoaffective Disorder: A mental disorder that combines symptoms of schizophrenia and a mood disorder. It can cause hallucinations, delusions, and mood swings.
4. Brief Psychotic Disorder: A short-term episode of psychosis that can be triggered by a stressful event. It can cause hallucinations, delusions, and a break from reality.
5. Postpartum Psychosis: A rare condition that occurs in some new mothers after childbirth. It can cause hallucinations, delusions, and a break from reality.
6. Drug-Induced Psychosis: A psychotic episode caused by taking certain medications or drugs. It can cause hallucinations, delusions, and a break from reality.
7. Alcohol-Related Psychosis: A psychotic episode caused by alcohol use disorder. It can cause hallucinations, delusions, and a break from reality.
8. Trauma-Related Psychosis: A psychotic episode caused by a traumatic event. It can cause hallucinations, delusions, and a break from reality.
9. Psychotic Disorder Not Otherwise Specified (NOS): A catch-all diagnosis for psychotic episodes that do not meet the criteria for any other specific psychotic disorder.

Symptoms of psychotic disorders can vary depending on the individual and the specific disorder. Common symptoms include:

1. Hallucinations: Seeing, hearing, or feeling things that are not there.
2. Delusions: False beliefs that are not based in reality.
3. Disorganized thinking and speech: Difficulty organizing thoughts and expressing them in a clear and logical manner.
4. Disorganized behavior: Incoherent or bizarre behavior, such as dressing inappropriately for the weather or neglecting personal hygiene.
5. Catatonia: A state of immobility or abnormal movement, such as rigidity or agitation.
6. Negative symptoms: A decrease in emotional expression or motivation, such as a flat affect or a lack of interest in activities.
7. Cognitive impairment: Difficulty with attention, memory, and other cognitive functions.
8. Social withdrawal: Avoidance of social interactions and relationships.
9. Lack of self-care: Neglecting personal hygiene, nutrition, and other basic needs.
10. Suicidal or homicidal ideation: Thoughts of harming oneself or others.

It's important to note that not everyone with schizophrenia will experience all of these symptoms, and some people may experience additional symptoms not listed here. Additionally, the severity and frequency of symptoms can vary widely from person to person. With proper treatment and support, many people with schizophrenia are able to manage their symptoms and lead fulfilling lives.

The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) defines Autistic Disorder as a pervasive developmental disorder that meets the following criteria:

A. Persistent deficits in social communication and social interaction across multiple contexts, including:

1. Deficits in social-emotional reciprocity (e.g., abnormal or absent eye contact, impaired understanding of facial expressions, delayed or lack of response to social overtures).
2. Deficits in developing, maintaining, and understanding relationships (e.g., difficulty initiating or sustaining conversations, impairment in understanding social norms, rules, and expectations).
3. Deficits in using nonverbal behaviors to regulate social interaction (e.g., difficulty with eye contact, facial expressions, body language, gestures).

B. Restricted, repetitive patterns of behavior, interests, or activities, as manifested by at least one of the following:

1. Stereotyped or repetitive motor movements, use of objects, or speech (e.g., hand flapping, head banging, repeating words or phrases).
2. Insistence on sameness, inflexibility, and adherence to routines or rituals.
3. Preoccupation with specific interests or activities that are repeated in a rigid and restricted manner (e.g., preoccupation with a particular topic, excessive focus on a specific activity).

C. Symptoms must be present in the early developmental period and significantly impact social, occupational, or other areas of functioning.

D. The symptoms do not occur exclusively during a medical or neurological condition (e.g., intellectual disability, hearing loss).

It is important to note that Autistic Disorder is a spectrum disorder and individuals with this diagnosis may have varying degrees of severity in their symptoms. Additionally, there are several other Pervasive Developmental Disorders (PDDs) that have similar diagnostic criteria but may differ in severity and presentation. These include:

A. Asperger's Disorder: Characterized by difficulties with social interaction and communication, but without the presence of significant delay or retardation in language development.

B. Rett Syndrome: A rare genetic disorder that is characterized by difficulties with social interaction, communication, and repetitive behaviors.

C. Childhood Disintegrative Disorder: Characterized by a loss of language and social skills that occurs after a period of normal development.

It is important to consult with a qualified professional, such as a psychologist or psychiatrist, for an accurate diagnosis and appropriate treatment.

The word schizophrenia comes from Greek roots meaning "split mind." It was coined by Swiss psychiatrist Eugen Bleuler in 1911 to describe the splitting or fragmentation of thought processes, feelings, and sense of self that can occur in the disorder. The word is often used interchangeably with the term mental illness or mental disorder.

Schizophrenia is a chronic, severe, and debilitating mental illness characterized by symptoms such as delusions, hallucinations, disorganized thinking and behavior, and negative symptoms like a lack of motivation or emotional expression. The disorder affects about 1 percent of the population worldwide and is often accompanied by other conditions such as depression, anxiety disorders, and substance abuse.

The causes of schizophrenia are still not fully understood, but research suggests that it may involve a combination of genetic, environmental, and neurochemical factors. There is no cure for the disorder, but treatment with medications and various forms of therapy can help to manage symptoms and improve quality of life.

There are several types of atrophy that can occur in different parts of the body. For example:

1. Muscular atrophy: This occurs when muscles weaken and shrink due to disuse or injury.
2. Neuronal atrophy: This occurs when nerve cells degenerate, leading to a loss of cognitive function and memory.
3. Cardiac atrophy: This occurs when the heart muscle weakens and becomes less efficient, leading to decreased cardiac output.
4. Atrophic gastritis: This is a type of stomach inflammation that can lead to the wasting away of the stomach lining.
5. Atrophy of the testes: This occurs when the testes shrink due to a lack of use or disorder, leading to decreased fertility.

Atrophy can be diagnosed through various medical tests and imaging studies, such as MRI or CT scans. Treatment for atrophy depends on the underlying cause and may involve physical therapy, medication, or surgery. In some cases, atrophy can be prevented or reversed with proper treatment and care.

In summary, atrophy is a degenerative process that can occur in various parts of the body due to injury, disease, or disuse. It can lead to a loss of function and decreased quality of life, but with proper diagnosis and treatment, it may be possible to prevent or reverse some forms of atrophy.

There are several types of learning disorders, including:

1. Dyslexia: A learning disorder that affects an individual's ability to read and spell words. Individuals with dyslexia may have difficulty recognizing letters, sounds, or word patterns.
2. Dyscalculia: A learning disorder that affects an individual's ability to understand and perform mathematical calculations. Individuals with dyscalculia may have difficulty with numbers, quantities, or mathematical concepts.
3. Dysgraphia: A learning disorder that affects an individual's ability to write and spell words. Individuals with dysgraphia may have difficulty with hand-eye coordination, fine motor skills, or language processing.
4. Attention Deficit Hyperactivity Disorder (ADHD): A neurodevelopmental disorder that affects an individual's ability to focus, pay attention, and regulate their behavior. Individuals with ADHD may have difficulty with organization, time management, or following instructions.
5. Auditory Processing Disorder: A learning disorder that affects an individual's ability to process and understand auditory information. Individuals with auditory processing disorder may have difficulty with listening, comprehension, or speech skills.
6. Visual Processing Disorder: A learning disorder that affects an individual's ability to process and understand visual information. Individuals with visual processing disorder may have difficulty with reading, writing, or other tasks that require visual processing.
7. Executive Function Deficits: A learning disorder that affects an individual's ability to plan, organize, and execute tasks. Individuals with executive function deficits may have difficulty with time management, organization, or self-regulation.

Learning disorders can be diagnosed by a trained professional, such as a psychologist, neuropsychologist, or learning specialist, through a comprehensive assessment that includes cognitive and academic testing, as well as a review of the individual's medical and educational history. The specific tests and assessments used will depend on the suspected type of learning disorder and the individual's age and background.

There are several approaches to treating learning disorders, including:

1. Accommodations: Providing individuals with accommodations, such as extra time to complete assignments or the option to take a test orally, can help level the playing field and enable them to succeed academically.
2. Modifications: Making modifications to the curriculum or instructional methods can help individuals with learning disorders access the material and learn in a way that is tailored to their needs.
3. Therapy: Cognitive-behavioral therapy (CBT) and other forms of therapy can help individuals with learning disorders develop strategies for managing their challenges and improving their academic performance.
4. Assistive technology: Assistive technology, such as text-to-speech software or speech-to-text software, can help individuals with learning disorders access information and communicate more effectively.
5. Medication: In some cases, medication may be prescribed to help manage symptoms associated with learning disorders, such as attention deficit hyperactivity disorder (ADHD).
6. Multi-sensory instruction: Using multiple senses (such as sight, sound, and touch) to learn new information can be helpful for individuals with learning disorders.
7. Self-accommodations: Teaching individuals with learning disorders how to identify and use their own strengths and preferences to accommodate their challenges can be effective in helping them succeed academically.
8. Parental involvement: Encouraging parents to be involved in their child's education and providing them with information and resources can help them support their child's learning and development.
9. Collaboration: Collaborating with other educators, professionals, and family members to develop a comprehensive treatment plan can help ensure that the individual receives the support they need to succeed academically.

It is important to note that each individual with a learning disorder is unique and may respond differently to different treatments. A comprehensive assessment and ongoing monitoring by a qualified professional is necessary to determine the most effective treatment plan for each individual.

There are several types of mood disorders, including:

1. Major Depressive Disorder (MDD): This is a condition characterized by persistent feelings of sadness, hopelessness, and a loss of interest in activities that were once enjoyed. It can also involve changes in appetite, sleep patterns, and energy levels.
2. Bipolar Disorder: This is a condition that involves periods of mania or hypomania (elevated mood) alternating with episodes of depression.
3. Persistent Depressive Disorder (PDD): This is a condition characterized by persistent low mood, lasting for two years or more. It can also involve changes in appetite, sleep patterns, and energy levels.
4. Postpartum Depression (PPD): This is a condition that occurs in some women after childbirth, characterized by feelings of sadness, anxiety, and a lack of interest in activities.
5. Seasonal Affective Disorder (SAD): This is a condition that occurs during the winter months, when there is less sunlight. It is characterized by feelings of sadness, lethargy, and a lack of energy.
6. Anxious Distress: This is a condition characterized by excessive worry, fear, and anxiety that interferes with daily life.
7. Adjustment Disorder: This is a condition that occurs when an individual experiences a significant change or stressor in their life, such as the loss of a loved one or a job change. It is characterized by feelings of sadness, anxiety, and a lack of interest in activities.
8. Premenstrual Dysphoric Disorder (PMDD): This is a condition that occurs in some women during the premenstrual phase of their menstrual cycle, characterized by feelings of sadness, anxiety, and a lack of energy.

Mood disorders can be treated with a combination of medication and therapy. Antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), are commonly used to treat mood disorders. These medications can help relieve symptoms of depression and anxiety by altering the levels of neurotransmitters in the brain.

Therapy, such as cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT), can also be effective in treating mood disorders. CBT helps individuals identify and change negative thought patterns and behaviors that contribute to their depression, while IPT focuses on improving communication skills and relationships with others.

In addition to medication and therapy, lifestyle changes such as regular exercise, healthy eating, and getting enough sleep can also be helpful in managing mood disorders. Support from family and friends, as well as self-care activities such as meditation and relaxation techniques, can also be beneficial.

It is important to seek professional help if symptoms of depression or anxiety persist or worsen over time. With appropriate treatment, individuals with mood disorders can experience significant improvement in their symptoms and overall quality of life.

Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease, affecting approximately 1% of the population over the age of 60. It is more common in men than women and has a higher incidence in Caucasians than in other ethnic groups.

The primary symptoms of Parkinson's disease are:

* Tremors or trembling, typically starting on one side of the body
* Rigidity or stiffness, causing difficulty with movement
* Bradykinesia or slowness of movement, including a decrease in spontaneous movements such as blinking or smiling
* Postural instability, leading to falls or difficulty with balance

As the disease progresses, symptoms can include:

* Difficulty with walking, gait changes, and freezing episodes
* Dry mouth, constipation, and other non-motor symptoms
* Cognitive changes, such as dementia, memory loss, and confusion
* Sleep disturbances, including REM sleep behavior disorder
* Depression, anxiety, and other psychiatric symptoms

The exact cause of Parkinson's disease is not known, but it is believed to involve a combination of genetic and environmental factors. The disease is associated with the degradation of dopamine-producing neurons in the substantia nigra, leading to a deficiency of dopamine in the brain. This deficiency disrupts the normal functioning of the basal ganglia, a group of structures involved in movement control, leading to the characteristic symptoms of the disease.

There is no cure for Parkinson's disease, but various treatments are available to manage its symptoms. These include:

* Medications such as dopaminergic agents (e.g., levodopa) and dopamine agonists to replace lost dopamine and improve motor function
* Deep brain stimulation, a surgical procedure that involves implanting an electrode in the brain to deliver electrical impulses to specific areas of the brain
* Physical therapy to improve mobility and balance
* Speech therapy to improve communication and swallowing difficulties
* Occupational therapy to improve daily functioning

It is important for individuals with Parkinson's disease to work closely with their healthcare team to develop a personalized treatment plan that addresses their specific needs and improves their quality of life. With appropriate treatment and support, many people with Parkinson's disease are able to manage their symptoms and maintain a good level of independence for several years after diagnosis.

1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.

2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.

3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.

4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.

5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.

6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.

7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.

8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.

9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.

10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.

The following are some common types of motor skill disorders:

1. Dyspraxia: This is a developmental condition that affects the ability to plan and perform movements. Individuals with dyspraxia may have difficulty with coordination, balance, and spatial awareness.
2. Apraxia: This is a neurological disorder that affects an individual's ability to perform voluntary movements despite having the physical strength and coordination to do so.
3. Ataxia: This is a condition that affects an individual's balance, coordination, and ability to perform purposeful movements. It can be caused by injury or disease to the cerebellum or other parts of the brain.
4. Parkinson's disease: This is a neurodegenerative disorder that affects movement, including fine motor skills such as writing and gross motor skills such as walking and balance.
5. Cerebral palsy: This is a developmental condition that can affect an individual's ability to move and control their body. It can impact both fine and gross motor skills.
6. Stroke: A stroke occurs when the blood supply to the brain is interrupted, leading to damage to the brain tissue. This can result in difficulty with movement, including fine and gross motor skills.
7. Traumatic brain injury: This occurs when the brain is injured as a result of a blow or jolt to the head. It can lead to difficulties with movement, memory, and other cognitive functions.
8. Spinal cord injury: This occurs when the spinal cord is damaged, either from trauma or disease. It can result in loss of movement and sensation below the level of the injury.
9. Multiple sclerosis: This is a chronic autoimmune disease that affects the central nervous system, including the brain and spinal cord. It can cause difficulties with movement, balance, and coordination.
10. Spina bifida: This is a congenital condition in which the spine does not properly close during fetal development. It can result in a range of physical and cognitive disabilities, including difficulty with movement and coordination.

It's important to note that these conditions can have varying levels of severity and impact on an individual's ability to move and control their body. Additionally, there are many other conditions and diseases that can affect the nervous system and result in difficulties with movement.

Types of Language Disorders:

1. Developmental Language Disorder (DLD): This is a condition where children have difficulty learning language skills, such as grammar, vocabulary, and sentence structure, despite being exposed to language in their environment. DLD can be diagnosed in children between the ages of 2 and 5.
2. Acquired Language Disorder: This is a condition that occurs when an individual experiences brain damage or injury that affects their ability to understand and produce language. Acquired language disorders can be caused by stroke, traumatic brain injury, or other neurological conditions.
3. Aphasia: This is a condition that occurs when an individual experiences damage to the language areas of their brain, typically as a result of stroke or traumatic brain injury. Aphasia can affect an individual's ability to understand, speak, read, and write language.
4. Dysarthria: This is a condition that affects an individual's ability to produce speech sounds due to weakness, paralysis, or incoordination of the muscles used for speaking. Dysarthria can be caused by stroke, cerebral palsy, or other neurological conditions.
5. Apraxia: This is a condition that affects an individual's ability to coordinate the movements of their lips, tongue, and jaw to produce speech sounds. Apraxia can be caused by stroke, head injury, or other neurological conditions.

Causes and Risk Factors:

1. Genetic factors: Some language disorders may be inherited from parents or grandparents.
2. Brain damage or injury: Stroke, traumatic brain injury, or other neurological conditions can cause acquired language disorders.
3. Developmental delays: Children with developmental delays or disorders, such as autism or Down syndrome, may experience language disorders.
4. Hearing loss or impairment: Children who have difficulty hearing may experience language delays or disorders.
5. Environmental factors: Poverty, poor nutrition, and limited access to educational resources can contribute to language disorders in children.

Signs and Symptoms:

1. Difficulty articulating words or sentences
2. Slurred or distorted speech
3. Limited vocabulary or grammar skills
4. Difficulty understanding spoken language
5. Avoidance of speaking or social interactions
6. Behavioral difficulties, such as aggression or frustration
7. Delayed language development in children
8. Difficulty with reading and writing skills

Treatment and Interventions:

1. Speech therapy: A speech-language pathologist (SLP) can work with individuals to improve their language skills through exercises, activities, and strategies.
2. Cognitive training: Individuals with language disorders may benefit from cognitive training programs that target attention, memory, and other cognitive skills.
3. Augmentative and alternative communication (AAC) devices: These devices can help individuals with severe language disorders communicate more effectively.
4. Behavioral interventions: Behavioral therapy can help individuals with language disorders manage their behavior and improve their social interactions.
5. Family support: Family members can provide support and encouragement to individuals with language disorders, which can help improve outcomes.
6. Educational accommodations: Individuals with language disorders may be eligible for educational accommodations, such as extra time to complete assignments or the use of a tape recorder during lectures.
7. Medication: In some cases, medication may be prescribed to help manage symptoms of language disorders, such as anxiety or depression.

Prognosis and Quality of Life:

The prognosis for individuals with language disorders varies depending on the severity of their condition and the effectiveness of their treatment. With appropriate support and intervention, many individuals with language disorders are able to improve their language skills and lead fulfilling lives. However, some individuals may experience ongoing challenges with communication and social interaction, which can impact their quality of life.

In conclusion, language disorders can have a significant impact on an individual's ability to communicate and interact with others. While there is no cure for language disorders, there are many effective treatments and interventions that can help improve outcomes. With appropriate support and accommodations, individuals with language disorders can lead fulfilling lives and achieve their goals.

Developmental disabilities can include a wide range of diagnoses, such as:

1. Autism Spectrum Disorder (ASD): A neurological disorder characterized by difficulties with social interaction, communication, and repetitive behaviors.
2. Intellectual Disability (ID): A condition in which an individual's cognitive abilities are below average, affecting their ability to learn, reason, and communicate.
3. Down Syndrome: A genetic disorder caused by an extra copy of chromosome 21, characterized by intellectual disability, delayed speech and language development, and a distinctive physical appearance.
4. Cerebral Palsy (CP): A group of disorders that affect movement, balance, and posture, often resulting from brain injury or abnormal development during fetal development or early childhood.
5. Attention Deficit Hyperactivity Disorder (ADHD): A neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity, and impulsivity.
6. Learning Disabilities: Conditions that affect an individual's ability to learn and process information, such as dyslexia, dyscalculia, and dysgraphia.
7. Traumatic Brain Injury (TBI): An injury to the brain caused by a blow or jolt to the head, often resulting in cognitive, emotional, and physical impairments.
8. Severe Hearing or Vision Loss: A condition in which an individual experiences significant loss of hearing or vision, affecting their ability to communicate and interact with their environment.
9. Multiple Disabilities: A condition in which an individual experiences two or more developmental disabilities simultaneously, such as intellectual disability and autism spectrum disorder.
10. Undiagnosed Developmental Delay (UDD): A condition in which an individual experiences delays in one or more areas of development, but does not meet the diagnostic criteria for a specific developmental disability.

These conditions can have a profound impact on an individual's quality of life, and it is important to provide appropriate support and accommodations to help them reach their full potential.

The term "amyloid" refers specifically to the type of protein aggregate that forms these plaques, and is derived from the Greek word for "flour-like." Amyloidosis is the general term used to describe the condition of having amyloid deposits in the body, while Alzheimer's disease is a specific type of amyloidosis that is characterized by the accumulation of beta-amyloid peptides in the brain.

Plaques, amyloid play a central role in the pathogenesis of many neurodegenerative diseases, and understanding their formation and clearance is an area of ongoing research. In addition to their role in Alzheimer's disease, amyloid plaques have been implicated in other conditions such as cerebral amyloid angiopathy, primary lateral sclerosis, and progressive supranuclear palsy.

Plaques, amyloid are composed of a variety of proteins, including beta-amyloid peptides, tau protein, and apolipoprotein E (apoE). The composition and structure of these plaques can vary depending on the underlying disease, and their presence is often associated with inflammation and oxidative stress.

In addition to their role in neurodegeneration, amyloid plaques have been implicated in other diseases such as type 2 diabetes and cardiovascular disease. The accumulation of amyloid fibrils in these tissues can contribute to the development of insulin resistance and atherosclerosis, respectively.

Overall, plaques, amyloid are a complex and multifaceted area of research, with many open questions remaining about their formation, function, and clinical implications. Ongoing studies in this field may provide valuable insights into the pathogenesis of various diseases and ultimately lead to the development of novel therapeutic strategies for these conditions.

In conclusion, plaques, amyloid are a hallmark of several neurodegenerative diseases, including Alzheimer's disease, and have been associated with inflammation, oxidative stress, and neurodegeneration. The composition and structure of these plaques can vary depending on the underlying disease, and their presence is often linked to the progression of the condition. Furthermore, amyloid plaques have been implicated in other diseases such as type 2 diabetes and cardiovascular disease, highlighting their potential clinical significance beyond neurodegeneration. Ongoing research into the mechanisms of amyloid plaque formation and clearance may lead to the development of novel therapeutic strategies for these conditions.

The exact cause of depressive disorder is not fully understood, but it is believed to involve a combination of genetic, environmental, and psychological factors. Some common risk factors for developing depressive disorder include:

* Family history of depression
* Traumatic events, such as abuse or loss
* Chronic stress
* Substance abuse
* Chronic illness or chronic pain

There are several different types of depressive disorders, including:

* Major depressive disorder (MDD): This is the most common type of depression, characterized by one or more major depressive episodes in a person's lifetime.
* Persistent depressive disorder (PDD): This type of depression is characterized by persistent, low-grade symptoms that last for two years or more.
* Bipolar disorder: This is a mood disorder that involves periods of both depression and mania or hypomania.
* Postpartum depression (PPD): This is a type of depression that occurs in women after childbirth.
* Severe depression: This is a severe and debilitating form of depression that can interfere with daily life and relationships.

Treatment for depressive disorder typically involves a combination of medication and therapy, such as antidepressant medications and cognitive-behavioral therapy (CBT). Other forms of therapy, such as psychodynamic therapy or interpersonal therapy, may also be effective. Lifestyle changes, such as regular exercise, healthy eating, and getting enough sleep, can also help manage symptoms.

It's important to seek professional help if you or someone you know is experiencing symptoms of depressive disorder. With proper treatment, many people are able to recover from depression and lead fulfilling lives.

Prodromal symptoms are like the sentinels of health, signaling that something is amiss before the full-blown disease or condition has manifested. By recognizing and addressing these early signs, individuals may be able to prevent or slow the progression of the underlying condition. However, it's important to note that not all prodromal symptoms will necessarily lead to a specific diagnosis, and proper medical evaluation is necessary for an accurate diagnosis and appropriate treatment.

Some common examples of prodromal symptoms include:

1. Fatigue: Feeling unusually tired or exhausted, which may be an early sign of an underlying chronic condition like fibromyalgia or chronic fatigue syndrome.
2. Muscle aches and pains: Experiencing joint or muscle pain that won't go away, which could be a sign of an autoimmune disorder like rheumatoid arthritis or lupus.
3. Digestive issues: Bloating, abdominal pain, or changes in bowel movements, which may indicate an underlying gastrointestinal condition like irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD).
4. Skin changes: Noticing unusual skin rashes, lesions, or discoloration, which could be an early sign of a condition like psoriasis, eczema, or melanoma.
5. Sleep disturbances: Difficulty falling or staying asleep, or experiencing vivid dreams or nightmares, which may indicate an underlying sleep disorder like insomnia or narcolepsy.
6. Mood changes: Feeling anxious, depressed, or having mood swings, which could be an early sign of a mental health condition like bipolar disorder or major depressive disorder.
7. Cognitive impairment: Difficulty concentrating, forgetfulness, or confusion, which may indicate an underlying neurological condition like Alzheimer's disease or Parkinson's disease.
8. Eye problems: Blurred vision, double vision, or seeing flashes of light, which could be an early sign of an eye condition like cataracts, glaucoma, or age-related macular degeneration.
9. Weight changes: Unexplained weight gain or loss, which may indicate an underlying hormonal imbalance, metabolic disorder, or other health issue.
10. Hearing problems: Difficulty hearing, ringing in the ears (tinnitus), or ear pain, which could be an early sign of an ear condition like otosclerosis or Meniere's disease.

If you are experiencing any of these symptoms, it is essential to consult with a healthcare professional for proper evaluation and diagnosis. Early detection and treatment can help manage symptoms and prevent long-term health complications.

Some common types of perceptual disorders include:

1. Visual perceptual disorders: These disorders affect an individual's ability to interpret and make sense of visual information from the environment. They can result in difficulties with recognizing objects, perceiving depth and distance, and tracking movement.
2. Auditory perceptual disorders: These disorders affect an individual's ability to interpret and make sense of sound. They can result in difficulties with hearing and understanding speech, as well as distinguishing between different sounds.
3. Tactile perceptual disorders: These disorders affect an individual's ability to interpret and make sense of touch. They can result in difficulties with recognizing objects through touch, as well as interpreting tactile sensations such as pain, temperature, and texture.
4. Olfactory perceptual disorders: These disorders affect an individual's ability to interpret and make sense of smells. They can result in difficulties with identifying different odors and distinguishing between them.
5. Gustatory perceptual disorders: These disorders affect an individual's ability to interpret and make sense of tastes. They can result in difficulties with identifying different flavors and distinguishing between them.
6. Balance and equilibrium disorders: These disorders affect an individual's ability to maintain balance and equilibrium. They can result in difficulties with standing, walking, and maintaining posture.

Perceptual disorders can have a significant impact on an individual's daily life, making it difficult to perform everyday tasks and activities. Treatment for perceptual disorders often involves a combination of sensory therapy, behavioral therapy, and assistive technologies. The goal of treatment is to help the individual compensate for any impairments in sensory processing and improve their ability to function in daily life.

Disease progression can be classified into several types based on the pattern of worsening:

1. Chronic progressive disease: In this type, the disease worsens steadily over time, with a gradual increase in symptoms and decline in function. Examples include rheumatoid arthritis, osteoarthritis, and Parkinson's disease.
2. Acute progressive disease: This type of disease worsens rapidly over a short period, often followed by periods of stability. Examples include sepsis, acute myocardial infarction (heart attack), and stroke.
3. Cyclical disease: In this type, the disease follows a cycle of worsening and improvement, with periodic exacerbations and remissions. Examples include multiple sclerosis, lupus, and rheumatoid arthritis.
4. Recurrent disease: This type is characterized by episodes of worsening followed by periods of recovery. Examples include migraine headaches, asthma, and appendicitis.
5. Catastrophic disease: In this type, the disease progresses rapidly and unpredictably, with a poor prognosis. Examples include cancer, AIDS, and organ failure.

Disease progression can be influenced by various factors, including:

1. Genetics: Some diseases are inherited and may have a predetermined course of progression.
2. Lifestyle: Factors such as smoking, lack of exercise, and poor diet can contribute to disease progression.
3. Environmental factors: Exposure to toxins, allergens, and other environmental stressors can influence disease progression.
4. Medical treatment: The effectiveness of medical treatment can impact disease progression, either by slowing or halting the disease process or by causing unintended side effects.
5. Co-morbidities: The presence of multiple diseases or conditions can interact and affect each other's progression.

Understanding the type and factors influencing disease progression is essential for developing effective treatment plans and improving patient outcomes.

The symptoms of Lewy body disease can vary from person to person, but they often include:

1. Cognitive problems, such as difficulty with memory, attention, and decision-making.
2. Slowness of movement, rigidity, and tremors, similar to those seen in Parkinson's disease.
3. Visual hallucinations and sleep disturbances.
4. Balance problems and falls.
5. Mood changes, such as depression and anxiety.

Lewy body disease can be difficult to diagnose, as it can resemble other conditions such as Alzheimer's disease or Parkinson's disease. A definitive diagnosis is usually made through an autopsy after death, but a clinical diagnosis can be made based on a combination of symptoms and medical imaging studies.

There is no cure for Lewy body disease, but medications and therapies can help manage its symptoms. Treatment options may include cholinesterase inhibitors, dopamine agonists, and antidepressants, as well as physical, occupational, and speech therapy. In some cases, surgery may be recommended to regulate medication or improve cognitive function.

Lewy body disease is a relatively rare condition, affecting about 1% of people over the age of 65. It is more common in men than women, and the risk of developing the disease increases with age. There is currently no known cause for Lewy body disease, but research suggests that it may be linked to genetic factors and exposure to certain environmental toxins.

In summary, Lewy body disease is a progressive neurodegenerative disorder that affects the brain and nervous system, characterized by abnormal protein deposits called Lewy bodies. It can cause a range of cognitive and motor symptoms, and diagnosis can be challenging. There is no cure for the disease, but medications and therapies can help manage its symptoms.

The term "small vessel disease" encompasses a range of conditions that affect the small blood vessels in the brain, including:

1. Cerebral amyloid angiopathy (CAA): A condition characterized by the accumulation of beta-amyloid peptides in the walls of small blood vessels, leading to vascular inflammation and degeneration.
2. Cerebral infarction (CI): A condition caused by a blockage or rupture of small blood vessels in the brain, resulting in tissue damage or death due to lack of oxygen and nutrients.
3. Leukoaraiosis: A condition characterized by the degeneration of white matter in the brain, leading to a loss of myelin and axonal damage.
4. Moyamoya disease (MMD): A rare condition caused by stenosis or occlusion of the internal carotid artery and its branches, leading to decreased blood flow to the brain.
5. Small vessel ischemic change (SVIC): A condition characterized by the degeneration of small blood vessels in the brain due to chronic hypoperfusion or other factors.
6. Vasculitis: An inflammatory condition affecting the blood vessels in the brain, leading to damage and scarring.
7. Other conditions such as hypertension, diabetes, and hyperlipidemia can also contribute to the development of CSVD.

The exact pathophysiology of CSVD is complex and involves multiple factors, including genetic predisposition, aging, inflammation, oxidative stress, and vascular damage. The symptoms of CSVD can vary depending on the location and severity of the affected blood vessels, but may include cognitive decline, memory loss, difficulty with speech and language, weakness or numbness in the limbs, and vision problems.

CSVD is often difficult to diagnose, as its symptoms can be similar to other conditions such as Alzheimer's disease or stroke. A comprehensive diagnostic workup may include a physical examination, medical history, neuroimaging studies (such as CT or MRI scans), and laboratory tests to rule out other conditions.

There is currently no cure for CSVD, but various treatment options are available to manage its symptoms and slow its progression. These may include medications to control hypertension, diabetes, and hyperlipidemia; lifestyle modifications such as regular exercise and a healthy diet; and rehabilitation therapies to improve cognitive and motor function. In severe cases, surgical interventions such as bypass surgery or endarterectomy may be necessary.

In conclusion, CSVD is a complex and multifactorial condition that affects the blood vessels in the brain, leading to a range of cognitive and motor symptoms. While there is currently no cure for CSVD, various treatment options are available to manage its symptoms and slow its progression. Early detection and management of underlying risk factors can help to slow the progression of CSVD and improve outcomes for affected individuals.

There are several subtypes of FTD, each with distinct clinical features and rates of progression. The most common subtypes include:

1. Behavioral variant FTD (bvFTD): This subtype is characterized by changes in personality, behavior, and social conduct, such as a lack of empathy, impulsivity, and aggression.
2. Language variant FTD (lvFTD): This subtype is characterized by progressive language decline, including difficulty with word-finding, syntax, and comprehension.
3. Primary progressive agrammatic alexia (PPA): This subtype is characterized by progressive loss of language abilities, including grammar and word retrieval.
4. Progressive supranuclear palsy (PSP): This subtype is characterized by slow movement, rigidity, and dementia, with a higher risk of developing parkinsonism.

The exact cause of FTD is not yet fully understood, but it is believed to be linked to abnormal protein accumulation in the brain, including tau and TDP-43 proteins. There is currently no cure for FTD, but various medications and therapies can help manage its symptoms and slow its progression.

FTD can be challenging to diagnose, as it can resemble other conditions such as Alzheimer's disease or frontal lobe lesions. A definitive diagnosis is typically made through a combination of clinical evaluation, neuroimaging, and pathological analysis of brain tissue after death.

FTD has a significant impact on patients and their families, affecting not only cognitive function but also behavior, mood, and social relationships. It can also place a significant burden on caregivers, who may need to provide around-the-clock support and assistance.

Overall, FTD is a complex and heterogeneous disorder that requires further research to better understand its causes, improve diagnostic accuracy, and develop effective treatments.

There are different types of amnesia, including:

1. Retrograde amnesia: loss of memory of events that occurred before the onset of amnesia.
2. Anterograde amnesia: inability to form new memories after the onset of amnesia.
3. Transient global amnesia: temporary and reversible loss of memory due to a specific cause, such as a stroke or a head injury.
4. Korsakoff's syndrome: a condition caused by alcoholism and malnutrition that affects the hippocampus and the ability to form new memories.
5. Dissociative amnesia: loss of memory due to psychological trauma or stress, often accompanied by dissociation from reality.

The symptoms of amnesia can vary depending on the underlying cause and the severity of the condition. Some common symptoms include:

1. Difficulty learning new information
2. Forgetting recent events or conversations
3. Inability to recall past events or experiences
4. Confusion and disorientation
5. Difficulty with problem-solving and decision-making

The diagnosis of amnesia is based on a combination of medical history, physical examination, and neuropsychological tests. Imaging studies such as CT or MRI scans may also be used to rule out other causes of memory loss.

Treatment for amnesia depends on the underlying cause and may include:

1. Medications to manage symptoms such as anxiety, depression, or cognitive impairment.
2. Cognitive rehabilitation therapy to improve memory and problem-solving skills.
3. Behavioral interventions to help the individual adapt to their condition.
4. In some cases, surgery may be necessary to treat the underlying cause of amnesia, such as a tumor or a blood clot.

Overall, amnesia can have a significant impact on an individual's quality of life, but with proper diagnosis and treatment, many people are able to manage their symptoms and lead fulfilling lives.

These and other approaches to the analysis of cognition (such as embodied cognition) are synthesized in the developing field of ... There are generally two components of metacognition: (1) knowledge about cognition and (2) regulation of cognition. Metamemory ... The Search for a Theory of Cognition: Early Mechanisms and New Ideas. Amsterdam: Rodopi. p. XIV. Matlin M (2009). Cognition. ... Cognitive psychology Look up cognition in Wiktionary, the free dictionary. Cognition An international journal publishing ...
... www.spatial-cognition.de/ What is Spatial Cognition? An article describing spatial cognition The Spatial Intelligence and ... Cognition. 129 (1): 24-30. doi:10.1016/j.cognition.2013.05.013. PMID 23820180. S2CID 16842491. Taylor, Holly A; Tversky, ... Cognition. 101 (1): 153-172. doi:10.1016/j.cognition.2005.09.005. PMID 16359653. S2CID 8201650. Burgess, Neil (2006). "Spatial ... work together to understand spatial cognition in different species, especially in humans. Thereby, spatial cognition studies ...
There is evidence that numerical cognition is intimately related to other aspects of thought - particularly spatial cognition. ... also influence numerical cognition. They identify the manifestations of these heuristics in numerical cognition as: the left- ... Cognition. 120 (2): 225-235. doi:10.1016/j.cognition.2011.05.001. PMID 21640338. S2CID 16362508. Piazza, M.; Eger, E. (2016). " ... Numerical cognition is a subdiscipline of cognitive science that studies the cognitive, developmental and neural bases of ...
Fulbright, Ron; Walters, Grover (2020). "Synthetic Expertise". Augmented Cognition. Human Cognition and Behavior. 12197: 27-48 ... Augmented social cognition: using social web technology to enhance the ability of groups to remember, think, and reason. In ... The Augmented Cognition International (ACI) Society held its first conference in July 2005. At the society's first conference, ... Augmented cognition is an interdisciplinary area of psychology and engineering, attracting researchers from the more ...
... has been shown to implicate our affective (emotional), social and abstract cognitions. The ability to ... Steering cognition enables the use of limited cognitive resources to make sense of the world that someone expects to see. ... In psychology, steering cognition is a model of a cognitive executive function which contributes to how attention is regulated ... Steering cognition has been shown to depend on our ability to mental simulate or imagine ourselves performing tasks and ...
... extended cognition, and situated cognition. Thus, the embodiment thesis can be specified as follows: Many features of cognition ... animal cognition, plant cognition, and neurobiology. Proponents of the embodied cognition thesis emphasize the active and ... and mechanisms of cognition. Embodying cognition requires the different features of cognition such as perception, language, ... making it possible to separate embodied cognition, extended cognition, and situated cognition. In contrast to the embodiment ...
... spatial cognition, tools use, problem solving, and concepts. Unlike in animal behavior the concept of group cognition plays a ... more recent studies show that individual cognition exists and plays a role in overall group cognitive task. Insect cognition ... Cognition shapes how an insect comes to find its food. The particular cognitive abilities used by insects in finding food has ... The spatial cognition demands of foraging has been implicated in cases where more sophisticated mushroom bodies have evolved. ...
... , sometimes known as epistemological beliefs, or personal epistemology, is "cognition about knowledge and ... Alongside investigation of learner epistemic cognition, a parallel line of work has investigated teacher epistemic cognition, ... epistemic cognition research, largely from the learning sciences community, has found that epistemic cognition is related to ... Research on epistemic cognition has drawn on research in epistemology, the area of philosophy concerned with the nature of ...
The cultural cognition of risk, sometimes called simply cultural cognition, is the hypothesized tendency to perceive risks and ... Cultural Cognition Project website Public Lecture on Cultural Cognition by Dan Kahan, University of Florida, Oct. 6, 2009 (Harv ... "Cultural Cognition as a Conception of the Cultural Theory of Risk", Cultural Cognition Project Working Paper No. 73 Kahan, Dan ... Cultural cognition is a descendant of two other theories of risk perception. The first is the cultural theory of risk ...
... also plays a role in social cognition. People tend to see objects and individuals as more encouraging or ... Therefore, the cognition to act dangerously is an oblivious development. Research for implicit cognition has started to grow ... Implicit cognition is often immediately affective towards a person's reaction. Implicit cognitions also consisted of negative ... Negativity is a characteristic of implicit cognition since it is an automated response. Explicit cognition is rarely used when ...
... is animal cognition as present in elephants. Most contemporary ethologists view the elephant as one of the ... Animal cognition Spindle neuron Tool use Vocal learning Herculano-Houzel, Suzana; Avelino-de-Souza, Kamilla; Neves, Kleber; ... The Truth Behind Elephant Brainpower by BBC News Elephant Cognition in Primate Perspective by Richard W. Byrne and Lucy A. ... doi:10.1111/j.1439-0310.2005.01133.x. Nissani, M. (2008). "Elephant Cognition: A Review of Recent Experiments". Gajah. 28: 44- ...
... encompasses the mental capacities of non-human animals including insect cognition. The study of animal ... 2006). Animal Spatial Cognition: Comparative, Neural, and Computational Approaches. [On-line]. Lund N (2002). Animal cognition ... Kamil A, Bond A. "Center for Avian Cognition". University of Nebraska. "Animal Cognition Network". Archived from the original ... Wikiquote has quotations related to Animal cognition. Wikimedia Commons has media related to Animal cognition. Allen C. "Animal ...
... is the comparative study of the mechanisms and origins of cognition in various species, and is sometimes ... Alberta's Comparative Cognition and Behavior Page Comparative Cognition Lab at Cambridge University The Comparative Cognition ... and he concluded that the animal cognition is homologous to the human cognition. Thorndike's experiment established the field ... Use of felines in the study of comparative cognition is most associated with the work of Thorndike and his puzzle-boxes. ...
Distributed cognition Dynamical systems models of cognition Embodied cognition Extended cognition Enactivism Group cognition ... The issue is whether the situated aspect of cognition has only a practical value or it is somehow constitutive of cognition and ... Cognition and Technology Group at Vanderbilt. (1993). Anchored instruction and situated cognition revisited. Educational ... Grounded Cognition, concerned with the role of simulations and embodiment in cognition, encompasses Cognitive Linguistics, ...
... is a peer-reviewed academic journal covering cognitive science. It is published by Springer Science+Business ... "Memory & Cognition". 2014 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. 2015. Official website v t e ... "Memory & Cognition". NLM Catalog. National Center for Biotechnology Information. Retrieved 2016-06-04. "PsycINFO Journal ...
One notable theory of social cognition is social schema theory, although it is not the basis of all social cognition studies ( ... Developmental psychologists study the development of social cognition abilities. Social cognition came to prominence with the ... Observational learning Online participation Paranoid social cognition Relational mobility Embodied cognition Situated cognition ... Cognition, Enactive cognition, Social learning theory, Social psychology, Social philosophy). ...
Free movement was not necessarily a criterion of cognition, they held. The authors gave five conditions of minimal cognition in ... The idea of cognition in plants was first explored by Charles Darwin in the late 1800s in the book The Power of Movement in ... Plant cognition or plant gnosophysiology is the study of the mental capacities of plants. It explores the idea that plants are ... Today, plant cognition is emerging as a field of research directed at experimentally testing the cognitive abilities of plants ...
... views a system of cognition as a set of representations propagated through specific media, and models the ... It is a framework for studying cognition rather than a type of cognition. This framework involves the coordination between ... In 1999, Gavriel Salomon stated that there were two classes of distributive cognition: shared cognition and off-loading[ ... ISBN 978-0-08-049141-7. Hutchins E. "Overview of Distributed Cognition Lecture" (PDF). Distributed Cognition and Human-Computer ...
Blechner has suggested that whenever disjunctive cognitions occur, the two aspects of cognition that are disjunctive are ... Disjunctive cognitions between what the person looks like and who the person is suggest two brain systems for those aspects of ... Disjunctive cognition is a common phenomenon in dreams, first identified by psychoanalyst Mark Blechner, in which two aspects ... An example of disjunctive cognition is "I was the opposite of what I actually look like. I was tall and lanky like Katharine ...
... is the study of the intellectual and behavioral skills of non-human primates, particularly in the fields of ... Primates are capable of high levels of cognition; some make tools and use them to acquire foods and for social displays; some ... Animal cognition Deep social mind Hominid intelligence Great ape language Primate empathy Michael Tomasello; Josep Call (1997 ... There is some controversy over whether tool use represents a higher level of physical cognition. Some studies suggest primates ...
Cognition is one of the few psychology journals of the 20th century that developed outside of the United States. The journal, ... Cognition: International Journal of Cognitive Science is a bimonthly peer-reviewed scientific journal covering cognitive ... "Cognition". ScienceDirect. Elsevier. Retrieved 20 November 2014. Schunn, C.D.; Crowley, K.; Okada, T. (2005). "Cognitive ...
... refers to an analytic viewpoint that looks beyond individual cognition to include the interaction of ... The philosophy of group cognition does not deny individual cognition, but calls for a re-thinking of the ontology, epistemology ... In this sense, the theory of small-group cognition complements theories like distributed cognition and cultural-historical ... Small-group cognition focuses on the small group as the unit of analysis. In this, it contrasts with theories that are oriented ...
The field of cognition may have benefitted from the use of connectionist networks, but setting up the neural network models can ... Computational cognition (sometimes referred to as computational cognitive science or computational psychology) is the study of ... Therefore, the results may be used as evidence for a broad theory of cognition without explaining the particular process ... Their works laid the foundation for symbolic AI and computational cognition, and even some advancements for cognitive science ...
... illustrates how clothing impacts human cognition based on the co-occurrence of its symbolic meaning and the ... Therefore, Adam and Galinsky concluded that the principle of enclothed cognition relies on the co-occurrence of two independent ... The result of the third experiment was the final evidence needed to effectively exhibit the enclothed cognition hypothesis. ... Adam and Galinsky's research on enclothed cognition illustrate the effects of the physical experience of wearing clothing as ...
... is the processing of perception, memory, learning, thought, and language without being aware of it. The ... Unconscious cognition: An intro (Use dmy dates from December 2022, Articles needing additional references from April 2013, All ... Greenwald AG, McGhee DE, Schwartz JL (June 1998). "Measuring individual differences in implicit cognition: the implicit ... Augusto, L. M. (2018). Transitions versus dissociations: A paradigm shift in unconscious cognition. Axiomathes, 28, 269-291. ...
... uses the mathematical formalism of quantum theory to inspire and formalize models of cognition that aim to be ... Thus, the quantum cognition approach can be considered an attempt to formalize contextuality of mental processes, by using the ... Quantum cognition is an emerging field which applies the mathematical formalism of quantum theory to model cognitive phenomena ... Quantum cognition is based on the quantum-like paradigm or generalized quantum paradigm or quantum structure paradigm that ...
The concept of motor cognition grasps the notion that cognition is embodied in action, and that the motor system participates ... Cognitive science Embodied cognition Embodied embedded cognition Motor imagery Pragmatism Procedural memory Sommerville, JA.; ... Media related to Motor cognition at Wikimedia Commons (Commons category link from Wikidata, Motor cognition, Social psychology ... Spaulding, Shannon (2013). "Mirror Neurons and Social Cognition Mirror Neurons and Social Cognition". Mind & Language. 28 (2): ...
... may partly be unconscious. Just as people are not aware of the larger part of their thoughts (cognition ... cognition), about stressful events that have happened or might happen, fall under the definition of perseverative cognition. ' ... perseverative cognition) with prolonged physiological stress responses. Therefore, it is the perseverative cognition, and not ... Perseverative cognition is a collective term in psychology for continuous thinking about negative events in the past or in the ...
In 1984, Susan Fiske and Shelley E. Taylor published the first social cognition book, Social Cognition. First proposed by Fritz ... "The Emergence of Social Cognition". The Oxford Handbook of Social Cognition. doi:10.1093/oxfordhb/9780199730018.013.0002. Fiske ... Drawing from social cognition theories, some scholars have argued voters might be still able to make rational decisions even if ... Political cognition refers to the study of how individuals come to understand the political world, and how this understanding ...
Cognition -- RDoC Element. Type of Element: Behavior. The following construct(s)/subconstruct(s) refer to this element.... * ... Home , Research , Research Funded by NIMH , Research Domain Criteria (RDoC) , Units of Analysis , Behaviors , Cognition. ...
Social cognition and quality of life. Family-social-cognition and social stimulation (F-SCIT). Memory, visual-spatial scanning ... Cognition in general. Targeted cognitive training (TCT). Global cognition, speed of processing, verbal working and learning ... Social cognition deficits. social cognition and interaction training (SCIT) and Control: coping skills groups. Emotion and ... Verbal and global cognition. Auditory training. Global cognition, speed of processing, verbal memory/learning, problem-solving ...
Scientists have decoded visual images from a dogs brain, offering a first look at how the canine mind reconstructs what it sees.
Prescription drugs designed to boost cognition in neurodevelopmental disorders do not boost cognitive performance in healthy ... Cognition-Boosting Smart Drugs Not So Smart for Healthy People - Medscape - Oct 21, 2022. ... VIENNA, Austria - Prescription drugs designed to boost cognition in neurodevelopmental disorders do not increase overall ...
Fiske, S. T., & Taylor, S. E. (1991). Social cognition. New York: McGraw-Hill. Hess, T. M. (1994). Social cognition in ... NORMAL CHANGES IN BASIC COGNITIVE SKILLS AND SOCIAL COGNITION Many models of social cognition emphasize the importance of basic ... Full Text PA-97-065 SOCIAL COGNITION AND AGING NIH GUIDE, Volume 26, Number 19, June 6, 1997 PA NUMBER: PA-97-065 P.T. 34 ... RESEARCH OBJECTIVES The NIA seeks grant applications for the study of social cognition and aging that address one or more of ...
Human cognition is a defining feature of human evolution, setting us apart from other primates. Despite over 100 million ... Computational Modeling Sheds Light on Human Cognition and the Origins of Brain Disorders. February 15, 2023. Researchers from ... used computational modeling to uncover mutations in the human genome that likely influenced the evolution of human cognition. ...
Why the effects of these hormone treatments on cognition differ by age is unknown. The scientists will continue to follow the ... Over 1,100 of the women participated in a telephone assessment of cognition an average of 7 years afterward. The study was ...
... Grant Number: 5R01DK065114-05. PI Name: ROSENBERG, ... Project Title: Renal Transplantation, Homocysteine Lowering & Cognition. Abstract: DESCRIPTION (provided by applicant) This ...
... Start: September 1, 2016. End: April 2021. Enrollment: 180 ... HomeMediterranean Diet, Weight Loss, and Cognition in Obese Older Adults. ...
Alzheimers gene protects cognition in Brazilian slums January / February 2014 , Volume 13, Issue 1 * Full January / February ... Home , Global Health Matters Jan/Feb 2014 , Alzheimers gene protects cognition in Brazilian slums Print ...
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Role of Sleep Apnea in Cognition and Alzheimers Disease Biomarkers in WTC Responders. ... PET/MR and cognition using a visual-spatial memory test. This study has the potential to identify the mechanisms by which sleep ...
... the effect of aerobic physical activity on cognition, academic achievement, and psychosocial function has not yet been ... Suggested citation for this article: Lees C, Hopkins J. Effect of Aerobic Exercise on Cognition, Academic Achievement, and ... Lastly, cognition was defined as a students ability to learn through perception, reasoning, analysis, and judgment, which is ... There was no documentation of APA having any negative impact on childrens cognition and psychosocial health, even in cases ...
CADASIL is an early onset small vessel disease and genetic variant of pure subcortical ischemic vascular dementia (SIVD). The condition has been invaluable in defining the profile and neuroimaging correlates of cognitive deficits in pure SIVD. The recent completion of a randomized trial in cognitive …
How much do you know about depression and cognition? Test your knowledge with this short quiz. ... MDD involves symptoms (which can be recurring) of both affect and cognition. Cognitive impairment is among the most frequent ... How much do you know about depression and cognition? Test your knowledge with this short quiz. ...
Neuron-glial interactions health and disease: from cognition to cancer Air date:. Wednesday, January 10, 2024, 2:00:00 PM. Time ...
A mechanistic model of connector hubs, modularity and cognition Maxwell A Bertolero 1 2 , B T Thomas Yeo 3 4 , Danielle S ... A mechanistic model of connector hubs, modularity and cognition Maxwell A Bertolero et al. Nat Hum Behav. 2018 Oct. ... The Segregation and Integration of Distinct Brain Networks and Their Relationship to Cognition. Cohen JR, DEsposito M. Cohen ... A mechanistic understanding of these hubs and how they support cognition has not been demonstrated. Here, we leveraged ...
Entry-level research assistant position(cognition in Parkinsons Disease) available in San Diego Gabe Castillo. March 17, 2014 ...
Center for Research on Concepts and Cognition ✖ Remove constraint Creator: Indiana University. Center for Research on Concepts ...
Laboratory of Brain and Cognition (LBC). Overview. The Laboratory of Brain and Cognition (LBC) is a branch of the Division of ...
In this study, we used fMRI to study abstract social cognition in children with WS and DUP7, as well as typically developing ( ... Neural correlates of abstract social cognition in Williams syndrome and 7q11.23 Duplication syndrome. Thursday, September 14, ...
... ... Title : Health and Cognition among Adults with and without Traumatic Brain Injury: A Matched Case-Control Study Personal Author ... Health and Cognition among Adults with and without Traumatic Brain Injury: A Matched Case-Control Study ... Among persons with TBI there was a stronger association between poorer self-rated health and cognition than controls. TBI is ...
BOLD Connectivity Dynamics & Relationship to On-Going Cognition 1st International Conference in Human Brain Development, Aug ...
... Human Brain Compresses Working Memories into Low-Res Summaries Posted on April 12th, 2022. by Lawrence Tabak, D.D. ... Tags: aging, Alzheimers, Alzheimers disease, beta amyloid, brain, cognition, dementia, memory, sleep, sleep loss, sleep-wake ... Tags: brain, brain activity, brain imaging, brain motion, cognition, fMRI, imaging, memory, memory processing, neuroscience, ... Tags: aging, Alzheimers blood test, Alzheimers disease, blood test, brain, cognition, cognitive decline, dementia, ...
... may preserve memory and cognition over time, new research shows. ... Kale for Cognition When the investigators broke flavonols into ... Cite this: More Evidence Flavanols in Tea, Fruit, and Veg Preserve Memory, Cognition - Medscape - Aug 20, 2022. ... Consumption of flavonols may preserve memory and cognition over time, new research suggests. Three specific components of ... To determine rates of cognitive decline, researchers used an overall global cognition score summarizing 19 cognitive tests. The ...
MASSON MAROLDI, Marcelo. Computation and cognition. Ciênc. cogn. [online]. 2006, vol.7, n.1, pp. 122-127. ISSN 1806-5821. ... Palavras-chave : Computation; cognition; artificial intelligence; computational theory of mind. · resumo em Português · texto ... However, the value of computing in the study of cognition can no longer be ignored. The possibility of modeling human cognitive ... The limits in the cognition study through the analogy with digital computers is of ultimate relevance to the understanding and ...
... 1. Leibel DK, Shaked D, Beatty Moody DL, Liu HB, Weng NP, Evans MK, Zonderman AB, Waldstein SR. ...
Cognition. Cognitive changes can also impair driving ability in the elderly population. In a study by Carr and colleagues, 60% ... Factors affecting driving ability include physiologic factors, vision and hearing, cognition, distractions while driving, ... Salients are evaluations of the following: information processing, memory, cognition, sensation, proprioception, coordination, ... is independently associated with poorer performance on measures of global cognition, executive function, memory, and processing ...
The brains complexity and how its coordinated actions of billions of neurons shape our behavior and cognition have always ...
  • In addition to its effects on sensory processing and waking behavior, norepinephrine is now recognized as a contributor to various aspects of cognition, including attention, behavioral flexibility, working memory, and long-term mnemonic processes. (hindawi.com)
  • In this review, we will summarize the role and actions of NE in PFC and hippocampus and how it contributes to behavior and cognition. (hindawi.com)
  • Certain thinking styles promote criminal behavior, and these criminogenic cognitions are not engaged in equally by all offenders. (ojp.gov)
  • Although it can cause word-finding difficulties, lamotrigine improves multiple areas of cognition, according to large open-label studies and a post-hoc analysis of controlled trials. (psychiatrictimes.com)
  • Furthermore, we will consider how both the LC proper and forebrain noradrenergic transmission are known to change in some disease states characterized by disordered cognition and how behavioral deficits in a multitude of neuropsychiatric and neurodegenerative diseases might allude to dysfunction of the noradrenergic system (Table 1 ). (hindawi.com)
  • Results of search for 'su:{Cognition. (who.int)
  • In the current investigation, the researchers sought to identify offenders most likely to engage in criminogenic cognitions on the basis of status variables (i.e., demographic, incarceration, and mental health variables) using data from 595 adult male incarcerated offenders. (ojp.gov)
  • Findings indicate that younger offenders, less educated offenders, Black and Hispanic offenders, single (i.e., not in a relationship) offenders, offenders without a violent index offense, offenders with a psychological disorder, and offenders not participating in mental health services all endorsed higher levels of some types of criminogenic cognitions. (ojp.gov)
  • Although the effects of aerobic physical activity (APA) on children's physical health is well characterized, the effect of aerobic physical activity on cognition, academic achievement, and psychosocial function has not yet been established. (cdc.gov)
  • There was no documentation of APA having any negative impact on children's cognition and psychosocial health, even in cases where school curriculum time was reassigned from classroom teaching to aerobic physical activity. (cdc.gov)
  • A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC - a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione - could improve many age-associated defects in older humans to improve muscle strength and cognition, and promote healthy aging. (bcm.edu)
  • Animal and small-scale human studies have suggested that reduced microbial diversity is associated with poorer cognition, but studies have not been conducted in community-based large and diverse populations. (medscape.com)
  • Members of the Social Cognition Research Group use primarily experimental behavioural and neuroimaging methods to investigate how cognition interacts with social factors in order to shape human judgment and behaviour, both in interpersonal and intergroup contexts. (uea.ac.uk)
  • Programs: Human Factors/Applied Cognition. (gmu.edu)
  • This concentration emphasizes the study of a combination of elements within human factors, applied cognition and neuroergonomics in its academic focus. (gmu.edu)
  • Applied cognition is the study of the characteristics of basic human perception and cognitive processes relevant to the human performance at work. (gmu.edu)
  • Human stress and cognition : an information processing approach / edited by Vernon Hamilton and David M. Warburton. (who.int)
  • The clinical hallmarks of delirium are decreased attention or awareness and a change in baseline cognition. (medscape.com)
  • However, more recent studies are beginning to show that people who have experienced childhood adversity may also have unique strengths and enhanced cognition in some areas. (madinamerica.com)
  • A large body of research supports a role for each of these in cognition and mood, though specific studies in bipolar disorder are scarce. (psychiatrictimes.com)
  • All studies showed that APA had a generally positive impact on children's cognition and psychosocial function. (cdc.gov)
  • Houve diferença estatisticamente support(p=0.045), and cognition(p=0.026) dimensions. (bvsalud.org)
  • Cognitive testing checks for problems with certain brain functions called "cognition. (medlineplus.gov)
  • Problems with cognition are called "cognitive impairment. (medlineplus.gov)
  • disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition). (medlineplus.gov)
  • This systematic review provides an overview of research elucidating the relationship between aerobic physical activity and children's cognition, academic achievement, and psychosocial function. (cdc.gov)
  • This systematic review provides an overview of research elucidating the relationship between aerobic physical activity and children's cognition, academic achievement, and psychosocial function. (cdc.gov)
  • All studies showed that APA had a generally positive impact on children's cognition and psychosocial function. (cdc.gov)
  • There was no documentation of APA having any negative impact on children's cognition and psychosocial health, even in cases where school curriculum time was reassigned from classroom teaching to aerobic physical activity. (cdc.gov)
  • Full Text PA-97-065 SOCIAL COGNITION AND AGING NIH GUIDE, Volume 26, Number 19, June 6, 1997 PA NUMBER: PA-97-065 P.T. 34 Keywords: Aging/Gerontology Cognitive Development/Process National Institute on Aging PURPOSE The National Institute on Aging (NIA) invites qualified researchers to submit research and training grant applications on social cognition and aging. (nih.gov)
  • This announcement is coordinated with the National Institute of Mental Health (NIMH), which supports a range of topics in social cognition, and with the National Institute of Child Health and Human Development (NICHD), which supports applications about the normative cognitive, social, motivational and affective development of children from infancy through adolescence. (nih.gov)
  • In this study, we used fMRI to study abstract social cognition in children with WS and DUP7, as well as typically developing (TD) children. (nih.gov)
  • The Laboratory of Brain and Cognition (LBC) is a branch of the Division of Intramural Research Programs ( IRP ) at the National Institute of Mental Health ( NIMH ). (nih.gov)
  • Fast Five Quiz: Depression and Cognition - Medscape - Dec 31, 2019. (medscape.com)
  • This article highlights some of the advances on cognition in CADASIL. (nih.gov)
  • VIENNA, Austria - Prescription drugs designed to boost cognition in neurodevelopmental disorders do not increase overall cognitive performance in healthy individuals - and may even reduce productivity, new research suggests. (medscape.com)
  • MDD involves symptoms (which can be recurring) of both affect and cognition. (medscape.com)
  • Researchers from the National Institutes of Health (NIH) used computational modeling to uncover mutations in the human genome that likely influenced the evolution of human cognition. (nih.gov)
  • Although the effects of aerobic physical activity (APA) on children's physical health is well characterized, the effect of aerobic physical activity on cognition, academic achievement, and psychosocial function has not yet been established. (cdc.gov)
  • We have found a very high prevalence of OSA in the World Trade Center responder population, and the present work will evaluate the impact of OSA on early markers of Alzheimer 's Disease using plasma biomarkers, PET/MR and cognition using a visual-spatial memory test. (cdc.gov)