Inferior Colliculi: The posterior pair of the quadrigeminal bodies which contain centers for auditory function.Superior Colliculi: The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching.Mesencephalon: The middle of the three primitive cerebral vesicles of the embryonic brain. Without further subdivision, midbrain develops into a short, constricted portion connecting the PONS and the DIENCEPHALON. Midbrain contains two major parts, the dorsal TECTUM MESENCEPHALI and the ventral TEGMENTUM MESENCEPHALI, housing components of auditory, visual, and other sensorimoter systems.Retinal Ganglion Cells: Neurons of the innermost layer of the retina, the internal plexiform layer. They are of variable sizes and shapes, and their axons project via the OPTIC NERVE to the brain. A small subset of these cells act as photoreceptors with projections to the SUPRACHIASMATIC NUCLEUS, the center for regulating CIRCADIAN RHYTHM.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Vena Cava, Inferior: The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Acoustic Stimulation: Use of sound to elicit a response in the nervous system.Auditory Cortex: The region of the cerebral cortex that receives the auditory radiation from the MEDIAL GENICULATE BODY.Electrodes: Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.Auditory Perception: The process whereby auditory stimuli are selected, organized, and interpreted by the organism.Sound: A type of non-ionizing radiation in which energy is transmitted through solid, liquid, or gas as compression waves. Sound (acoustic or sonic) radiation with frequencies above the audible range is classified as ultrasonic. Sound radiation below the audible range is classified as infrasonic.Auditory Pathways: NEURAL PATHWAYS and connections within the CENTRAL NERVOUS SYSTEM, beginning at the hair cells of the ORGAN OF CORTI, continuing along the eighth cranial nerve, and terminating at the AUDITORY CORTEX.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Thalamic Nuclei: Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.Potassium Channels, Voltage-Gated: Potassium channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. The opening of these channels is induced by the membrane depolarization of the ACTION POTENTIAL.Subthalamic Nucleus: Lens-shaped structure on the inner aspect of the INTERNAL CAPSULE. The SUBTHALAMIC NUCLEUS and pathways traversing this region are concerned with the integration of somatic motor function.Globus Pallidus: The representation of the phylogenetically oldest part of the corpus striatum called the paleostriatum. It forms the smaller, more medial part of the lentiform nucleus.Shaw Potassium Channels: A shaker subfamily that is prominently expressed in NEURONS and are necessary for high-frequency, repetitive firing of ACTION POTENTIALS.Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.Cochlear Nucleus: The brain stem nucleus that receives the central input from the cochlear nerve. The cochlear nucleus is located lateral and dorsolateral to the inferior cerebellar peduncles and is functionally divided into dorsal and ventral parts. It is tonotopically organized, performs the first stage of central auditory processing, and projects (directly or indirectly) to higher auditory areas including the superior olivary nuclei, the medial geniculi, the inferior colliculi, and the auditory cortex.Loudness Perception: The perceived attribute of a sound which corresponds to the physical attribute of intensity.HandbooksScala Vestibuli: The upper chamber of the COCHLEA that is filled with PERILYMPH. It is connected to SCALA TYMPANI via helicotrema at the apex of the cochlea.Cochlear Nerve: The cochlear part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The cochlear nerve fibers originate from neurons of the SPIRAL GANGLION and project peripherally to cochlear hair cells and centrally to the cochlear nuclei (COCHLEAR NUCLEUS) of the BRAIN STEM. They mediate the sense of hearing.Stapes: One of the three ossicles of the middle ear. It transmits sound vibrations from the INCUS to the internal ear (Ear, Internal see LABYRINTH).Tachycardia, Atrioventricular Nodal Reentry: Abnormally rapid heartbeats caused by reentry of atrial impulse into the dual (fast and slow) pathways of ATRIOVENTRICULAR NODE. The common type involves a blocked atrial impulse in the slow pathway which reenters the fast pathway in a retrograde direction and simultaneously conducts to the atria and the ventricles leading to rapid HEART RATE of 150-250 beats per minute.Neural Networks (Computer): A computer architecture, implementable in either hardware or software, modeled after biological neural networks. Like the biological system in which the processing capability is a result of the interconnection strengths between arrays of nonlinear processing nodes, computerized neural networks, often called perceptrons or multilayer connectionist models, consist of neuron-like units. A homogeneous group of units makes up a layer. These networks are good at pattern recognition. They are adaptive, performing tasks by example, and thus are better for decision-making than are linear learning machines or cluster analysis. They do not require explicit programming.Cochlear Implants: Electronic hearing devices typically used for patients with normal outer and middle ear function, but defective inner ear function. In the COCHLEA, the hair cells (HAIR CELLS, VESTIBULAR) may be absent or damaged but there are residual nerve fibers. The device electrically stimulates the COCHLEAR NERVE to create sound sensation.Cochlea: The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Electric Stimulation: Use of electric potential or currents to elicit biological responses.Cochlear Implantation: Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.Dipodomys: A genus of the family Heteromyidae which contains 22 species. Their physiology is adapted for the conservation of water, and they seldom drink water. They are found in arid or desert habitats and travel by hopping on their hind limbs.Biology: One of the BIOLOGICAL SCIENCE DISCIPLINES concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals, plants, and microorganisms.Echolocation: An auditory orientation mechanism involving the emission of high frequency sounds which are reflected back to the emitter (animal).Chiroptera: Order of mammals whose members are adapted for flight. It includes bats, flying foxes, and fruit bats.Hallucinations: Subjectively experienced sensations in the absence of an appropriate stimulus, but which are regarded by the individual as real. They may be of organic origin or associated with MENTAL DISORDERS.Civil Rights: Legal guarantee protecting the individual from attack on personal liberties, right to fair trial, right to vote, and freedom from discrimination on the basis of race, color, religion, sex, age, disability, or national origin. (from http://www.usccr.gov/ accessed 1/31/2003)Microwaves: That portion of the electromagnetic spectrum from the UHF (ultrahigh frequency) radio waves and extending into the INFRARED RAYS frequencies.Voice: The sounds produced by humans by the passage of air through the LARYNX and over the VOCAL CORDS, and then modified by the resonance organs, the NASOPHARYNX, and the MOUTH.Speech: Communication through a system of conventional vocal symbols.Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Neurosciences: The scientific disciplines concerned with the embryology, anatomy, physiology, biochemistry, pharmacology, etc., of the nervous system.Evoked Potentials, Auditory: The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.Galaxies: Large aggregates of CELESTIAL STARS; COSMIC DUST; and gas. (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed)
... inferior colliculi, cochlear and vestibular nuclei), and in retinal ganglion cells. Kv3.1/Kv3.2 conductance is necessary and ...
... about sound from the cochlear nucleus to various brainstem nuclei and ultimately the contralateral inferior colliculus of the ... The inferior colliculi (IC) are located just below the visual processing centers known as the superior colliculi. The central ... Ventral nuclei of lateral lemniscus help the inferior colliculus (IC) decode amplitude modulated sounds by giving both phasic ... Oliver, Douglas M. "Neuronal Organization in the Inferior Colliculus." Springer. 2005. Web. 27 Mar. 2016. Janata, Petr, and ...
Axons from the inferior colliculus constitute the brachium of the inferior colliculus and end in the medial geniculate. The ... From the cochlea, peripheral auditory information goes to the cochlear nucleus. From there, through the cochlear nerve, axons ... Axons from there constitute the lateral lemniscus which ends in the inferior colliculus. ... In the postero inferior part of the thalamus is a place which raises unsolved problems. This is a place of endings of ...
From there, the signals are projected to the inferior colliculus in the midbrain tectum. The inferior colliculus integrates ... The sound information from the cochlea travels via the auditory nerve to the cochlear nucleus in the brainstem. ... The inferior colliculus in turn projects to the medial geniculate nucleus, a part of the thalamus where sound information is ... a structure that vibrates when waves from the middle ear propagate through the cochlear fluid - endolymph. The basilar membrane ...
They reflect neuronal activity in the auditory nerve, cochlear nucleus, superior olive, and inferior colliculus of the ...
... several researchers have observed a suppression of cochlear neural output during stimulation of the inferior colliculus (IC) in ... 1985). "Numerical estimations of structures in the cochlear nuclei and cochlear afferents and efferents". Acta Otolaryngol ... activation via electrical stimulation of the inferior colliculus". J Neurophysiol. 90 (5): 3178-200. doi:10.1152/jn.00537.2003 ... Efferent Fibers of the Cochlear Nerve and Cochlear Nucleus". In Rasmussen, G. L.; Windle, W. F. Neural Mechanisms of the ...
... from synchronous responses in the cochlear nucleus and later becomes dependent on rate encoding in the inferior colliculus. ... The fluid found in these two cochlear chambers is perilymph, while scala media, or the cochlear duct, is filled with endolymph ... Cochlear hair cells are organized as inner hair cells and outer hair cells; inner and outer refer to relative position from the ... The apical surface of each cochlear hair cell contains a hair bundle. Each hair bundle contains approximately 300 fine ...
... with the inferior colliculus (IC). The dorsal cochlear nucleus (DCN) has input from the LL and output to the contralateral LL ... Transverse section of mid-brain at level of inferior colliculi. Scheme showing the course of the fibers of the lemniscus; ... about sound from the cochlear nucleus to various brainstem nuclei and ultimately the contralateral inferior colliculus of the ... The nucleus is primarily GABAergic, and projects bilaterally to the inferior colliculus, and contralaterally to the DNLL, with ...
Phase-locking to stimulus frequencies has been shown in the auditory nerve, the cochlear nucleus, the inferior colliculus, and ... Liu, L.-F.; Palmer, AR; Wallace, MN (2006). "Phase-Locked Responses to Pure Tones in the Inferior Colliculus". Journal of ... Amusic brains have been found in fMRI studies to have less white matter and thicker cortex than controls in the right inferior ... CBF increases in the inferior frontal polar cortex and right thalamus suggest that these regions may be related to retrieval ...
The output is via the ipsilateral lateral lemniscus to the inferior colliculus. The MSO responds better to binaural stimuli. ... Large multipolar cells project to the cochlear nucleus, but not the IC, in both cat and guinea pig. Inputs are often via end- ... Davis KA, Ramachandran R, May BJ (July 1999). "Single-unit responses in the inferior colliculus of decerebrate cats. II. ... Patterns of projection from the periolivary nuclei to the inferior colliculus". J. Comp. Neurol. 317 (4): 438-55. doi:10.1002/ ...
Transmissions from the SOC travel to the inferior colliculus (IC) via the lateral lemniscus. At the level of the IC, binaural ... The cochlear nerve spans from the cochlea of the inner ear to the ventral cochlear nuclei located in the pons of the brainstem ... Lim, DJ (1980). "Cochlear anatomy related to cochlear micromechanics. A review". J. Acoust. Soc. Am. 67 (5): 1686-1695. doi: ... Fibers from the left cochlear nucleus terminate on the left of MSO neurons, and fibers from the right cochlear nucleus ...
... and AMIs stimulates auditory neurons in the inferior colliculus. Cochlear implants have been very successful among these three ... Cochlear and brainstern auditory prostheses "neural interface for hearing restoration: Cochlear and brain stem implants". ... Proceedings of the Ieee 96:1076-84 J. K. Niparko and B. W. Wilson, "History of cochlear implants," in Cochlear Implants: ... Cochlear implants provide an example of such devices. These devices substitute the functions performed by the ear drum and ...
... the cochlear nuclei and the inferior colliculus), and from there to the medial geniculate nucleus of the thalamus and the ... both cortically and in subcortical structures such as the colliculi and geniculate nuclei of the thalamus. Single-cell ... with each other to ensure that ones with the same positional tags innervate the same area of the superior colliculus. First- ...
... through the cochlear nucleus, superior olivary complex, lateral lemniscus, to the inferior colliculus in the midbrain, on to ... The evoked potential is generated in the cochlea, goes through the cochlear nerve, ...
... prosthesis designed for stimulation of the inferior colliculus in deaf patients who cannot sufficiently benefit from cochlear ...
... cochlear nucleus, superior olive, and inferior colliculus of the brainstem. They typically have a response latency of no more ... Therefore, cochlear implantation was not performed. Published in 1994, this patient was monitored over the course of almost 20 ... Cochlear or auditory brainstem implantation could also be treatment options. Electrical stimulation of the peripheral auditory ... A case published in 2001 describes the patient as 20-year-old man referred for cochlear implants because of bilateral deafness ...
... then the inferior colliculus, then the medial geniculate body, before finally arriving at the primary auditory cortex. Mendoza ... is part of the auditory pathway where some of the axons coming from the cochlear nucleus (specifically, the anterior cochlear ... After nerves from the cochlear nucleus cross over in the trapezoid body and go on to the superior olivary nucleus, they ...
... and in turn projects to the inferior colliculus. The inferior colliculus receives direct, monosynaptic projections from the ... Most of these inputs terminate in the inferior colliculus, although there are a few small projections that bypass the inferior ... the ventral cochlear nucleus (VCN) and the dorsal cochlear nucleus (DCN). The ventral cochlear nucleus is unlayered whereas the ... The ventral cochlear nucleus(VCN) on the ventral aspect of the brain stem, ventrolateral to the inferior peduncle. The dorsal ...
Davis, K. A. (2002). "Evidence of a functionally segregated pathway from dorsal cochlear nucleus to inferior colliculus." J ... anterograde labeling of axonal layers from lateral superior olive and dorsal cochlear nucleus in the inferior colliculus of cat ... Along with the ventral cochlear nucleus (VCN), it forms the cochlear nucleus (CN), where all auditory nerve fibers from the ... of the inferior colliculus (CIC), but also receives efferent innervation from the auditory cortex, superior olivary complex and ...
Oliver, D. L. (1987). "Projections to the inferior colliculus from the anteroventral cochlear nucleus in the cat: possible ... Stellate/multipolar cells form the projection to both inferior colliculi (central nucleus and dorsal cortex), and synapse in a ... The anteroventral cochlear nucleus (AVCN) (or accessory), is placed between the two divisions of the cochlear nerve, and is on ... The ventral cochlear nucleus is divided into the anterior ventral (anteroventral) cochlear nucleus (AVCN) and the posterior ...
Neurons from the nucleus laminaris project to the core of the central nucleus of the inferior colliculus and to the anterior ... the cochlear nucleus magnocellularis (mammalian anteroventral cochlear nucleus) and the cochlear nucleus angularis (see figure ... These two nuclei are the starting points of two separate but parallel pathways to the inferior colliculus: the pathway from ... The time and sound-pressure pathways converge at the lateral shell of the central nucleus of the inferior colliculus. The ...
The inferior colliculus is the first place where vertically orienting data from the fusiform cells in the dorsal cochlear ... "inferior colliculus" at the BrainMaps project NIF Search - Brachium of inferior colliculus via the Neuroscience Information ... the nucleus of the brachium of the inferior colliculus (or inferior brachium) and deep layers of the superior colliculus. The ... only project to the contralateral inferior colliculus. This inferior colliculus contralateral to the ear it is receiving the ...
midbrain: Lateral lemniscus → Inferior colliculi →. *thalamus: Medial geniculate nuclei →. *cerebrum: Acoustic radiation → ... Cochlear nuclear complex. In mammals, the axons from each cochlear nerve terminate in the cochlear nuclear complex that ... inner ear: Hair cells → Spiral ganglion → Cochlear nerve VIII →. *pons: Cochlear nucleus (Anterior, Dorsal) → Trapezoid body → ... the posteroventral cochlear nucleus (PVCN). Each of the three cochlear nuclei are tonotopically organized. The axons from the ...
In the inferior colliculus (IC) all the major ascending pathways from the olivary complex and the central nucleus converge. The ... known as the antero-ventral cochlear nucleus (AVCN), postero-ventral cochlear nucleus (PVCN) and dorsal cochlear nucleus (DCN) ... is the main auditory tract in the brainstem connecting SOC to the inferior colliculus. The dorsal nucleus of the lateral ... frequency tuning and dynamic ranges of VNLL neurons supply the inferior colliculus with a variety of inputs, each enabling a ...
... inferior colliculus inferior concha inferior frontal gyrus inferior gluteal artery inferior horn inferior meatus inferior ... claustrum clava clavicle climbing fiber clinoid clitoris clivus cloaca clonus coccyx cochlea cochlear duct cochlear nerve ... inferior temporal gyrus inferior thyroid artery inferior thyroid vein Inferior tibiofibular joint inferior vena cava inferior ... mesenteric artery inferior mesenteric vein inferior nasal concha inferior oblique muscle inferior olivary nucleus inferior ...
Cochlear aqueduct. *Stylomastoid foramen. *fossae *Subarcuate fossa. *Jugular fossa. *canaliculi *Inferior tympanic ...
One of the most prominent points of interconnection is the commissure of the inferior colliculus (CoIC). Anatomical studies ... have revealed that these fibres make reciprocal connections which follow the tonotopic organisation of the inferior colliculus ... have revealed that these fibres make reciprocal connections which follow the tonotopic organisation of the inferior colliculus ... One of the most prominent points of interconnection is the commissure of the inferior colliculus (CoIC). Anatomical studies ...
Fingerprint Dive into the research topics of Differential afferent projections to the inferior colliculus from the cochlear ... Differential afferent projections to the inferior colliculus from the cochlear nucleus in the albino mouse. ...
... Academic Article * View record in ... The present study investigated changes in tuning properties of inferior colliculus (IC) neurons following compression of the ... contralateral cochlear nucleus (CN). The left CN in adult rats (n = 8) was exposed and a 32-channel acute recording probe ...
The inferior colliculus (IC) and the locus coeruleus (LC) are two midbrain nuclei that integrate multimodal information and ... The inferior colliculus (IC) and the locus coeruleus (LC) are two midbrain nuclei that integrate multimodal information and ... the cochlear root nucleus (Gómez-Nieto et al., 2008b) and the inferior colliculus (IC) (Klepper and Herbert, 1991). The IC is ... lateral cortex of the inferior colliculus; IA, Interaural level; IC, inferior colliculus; IHC, immunohistochemistry; ir, ...
... inferior colliculus; (6) medial geniculate body; and (7) possibly auditory radiation from the thalamus to temporal cortex.. Use ... Laboratory and clinical evidence now suggest the following wave origins: (1) auditory nerve; (2) cochlear nucleus; (3) superior ...
2000) Effects on cochlear responses of activation of descending pathways from the inferior colliculus. Hear Res 149:11-23, doi: ... 2006) Gentamicin abolishes all cochlear effects of electrical stimulation of the inferior colliculus. Exp Brain Res 174:35-44, ... 2006) Inferior colliculus stimulation causes similar efferent effects on ipsilateral and contralateral cochlear potentials in ... 1992) Frequency tuning properties of neurons in the inferior colliculus of an FM bat. J Comp Neurol 319:34-50, doi:10.1002/cne. ...
Ipsilateral cochlear nucleus. - Superior olives. - Inferior colliculi. - Medial geniculate nucleus. - Primary auditory cortex ...
Laminar inputs from dorsal cochlear nucleus and ventral cochlear nucleus to the central nucleus of the inferior colliculus: two ... dorsal cortex of the inferior colliculus; LCIC, lateral cortex of the inferior colliculus; RCIC, rostral cortex of the inferior ... 1999) Direct innervation of identified tectothalamic neurons in the inferior colliculus by axons from the cochlear nucleus. ... 2005) The inferior colliculus of the rat: a quantitative analysis of monaural frequency response areas. Neuroscience 132:203- ...
Ventral cochlear nucleus Superior olive Inferior colliculus Medial geniculate nucleus of thalamus Auditory cortex ... Cochlear implant Directly stimulates specific points on he basilar membrane to activate specific neurons in cranial nerve 8 ... They provide amplification of the sound - they amplify the signal from the tympanic membrane to cause the fluid in the cochlear ... Allows the cochlear to bulge out a little to reduce the pressure ... 2nd order neuron from the ventral cochlear nucleus decussates ...
... inferior colliculi, cochlear and vestibular nuclei), and in retinal ganglion cells. Kv3.1/Kv3.2 conductance is necessary and ...
... about sound from the cochlear nucleus to various brainstem nuclei and ultimately the contralateral inferior colliculus of the ... The inferior colliculi (IC) are located just below the visual processing centers known as the superior colliculi. The central ... Ventral nuclei of lateral lemniscus help the inferior colliculus (IC) decode amplitude modulated sounds by giving both phasic ... Oliver, Douglas M. "Neuronal Organization in the Inferior Colliculus." Springer. 2005. Web. 27 Mar. 2016. Janata, Petr, and ...
Immediate changes in tuning of inferior colliculus neurons following acute lesions of cat spiral ganglion. ... Single-unit responses in the inferior colliculus: effects of neonatal unilateral cochlear ablation.. *Leonard M. Kitzes, ... Frequency response areas in the inferior colliculus: nonlinearity and binaural interaction. *Jane Jie Yu, Eric D Young ... Retuning of Inferior Colliculus Neurons Following Spiral Ganglion Lesions: A Single-Neuron Model of Converging Inputs. * ...
1992) Projections to the inferior colliculus from the dorsal column nuclei. An experimental electron microscopic study in the ... 1999) Cochlear nerve projections to the small cell shell of the cochlear nucleus: The neuroanatomy of extremely thin sensory ... Type II Cochlear Ganglion Neurons Do Not Drive the Olivocochlear Reflex: Re-Examination of the Cochlear Phenotype in Peripherin ... Here, we provide evidence that unmyelinated type II cochlear afferents can report cochlear trauma, a potential trigger for ...
Inferior colliculus (Midbrain) Waves VI and VII. In normal hearing adults, the response to the click stimulus presented for ... Evaluation of hearing loss due to retro-cochlear pathology (lesion beyond the cochlea), like acoustic neuroma or acoustic ...
Effects of unilateral cochlear lesions on cochlear nucleus volume and projections to the inferior colliculus. J. Comp. Neurol. ... Long survival following cochlear removal progressively changes projections from the cochlear nucleus to the inferior colliculus ... Kitzes, L.M. and Semple, M.N. (1985) Single-unit responses in the inferior colliculus: effects of neonatal unilateral cochlear ... Moore, D. R. and Kitzes, L. M. (1985). Projections from the cochlear nucleus to the inferior colliculus in normal and ...
Because the cochlear nucleus is the first processing center in the brain receiving cochlear input, it is the first brainstem ... Research published over the last 30 years demonstrates changes in neural circuitry and activity in the cochlear nucleus that ... Tinnitus most commonly begins with alterations of input from the ear resulting from cochlear trauma or overstimulation of the ... Neuron Types, Intrinsic Circuits, and Plasticity in the Inferior Colliculus * Changes in the Inferior Colliculus Associated ...
AN: auditory nerve; CN: cochlear nucleus; GBC: globular bushy cell; IC: inferior colliculus; MNTB: medial nucleus of the ... A retrograde labeling study indicated that most LSO neurons that project to the inferior colliculus are principal cells (Saint ... Interaural time and intensity coding in superior olivary complex and inferior colliculus of the echolocating bat Molossus ater ... In addition, two labeled principal and one non-principal neuron, all of which projected to the ipsilateral inferior colliculus ...
... such as a cochlear implant, for delivering electrical plasticity informative stimuli to a neural network of an implantee. The ... 4. An implantable apparatus of claim 1 wherein the stimuli is delivered to the cochlea, inferior colliculus, the Subthalamic ... Successful use of a cochlear implant is associated with a habituation process during which a cochlear implant user learns to ... An implantable apparatus of claim 25 wherein the stimuli is delivered to the cochlea, inferior colliculus, the Subthalamic ...
Projections from the cochlear nuclear complex to the inferior colliculus. In: Winer JA, Schreiner CE (eds) The inferior ... projections from the inferior colliculus contact superior olivary cells that project bilaterally to the cochlear nuclei. J Comp ... Fan L, Carney LH (2017) Neural responses in the inferior colliculus to diotic tone-in-noise stimuli support detection based on ... In: Winer JA, Schreiner CE (eds) The inferior colliculus. Springer, New York, pp 346-376Google Scholar ...
Try google searches for cochlear nucleus, superior olive and inferior colliculus. You will find tons of online info on ... is probably the cochlear nucleus which is the first main integrative processing stage for auditory information. -Conscious- ...
The SOC sends projections primarily to the inferior colliculus (IC), while information from the dorsal cochlear nucleus (DCN) ... Kelly, J. B. and Caspary, D. M. (2005). Pharmacology of the inferior colliculus. In The Inferior colliculus (ed. J. A. Winer ... Portfors, C. V. and Sinex, D. G. (2005). Coding of communication sounds in the inferior colliculus. In The Inferior colliculus ... Comparison of the auditory sensitivity of neurons in the cochlear nucleus and inferior colliculus of young and aging C57BL/6J ...
The where pathway involves the ventral cochlear nuclei, the superior olivary complex and the inferior colliculus. The ... The MSO receives excitatory inputs from the cochlear nuclei on both sides and is tonotopica. Author(s): The Open University. ...
Cochlear Nucleus to. Superior Olivary Complex to Lateral Lemniscus to the Inferior Colliculus. ... Cochlear Nucleus to. Superior Olivary Complex to Lateral Lemniscus to the Inferior Colliculus. ... inferior colliculi. Central Auditory Mechanism. sound starts off as a physical even and ends up as a neural representation of ... Cochlear Nucleus to Superior to Lateral to Inferior. Connected fibers allow crossover between the two. ...
cochlear nucleus, . . inferior colliculus, . medial geniculate body, . and auditory cortex. . Rat blood ... and particularly the finding of increased activity in the vicinity of the colliculi, 79. or of the inferior colliculus 74. ... The inferior colliculus connects brainstem auditory centers to the medial geniculate body in the posterior thalamus from which ... which both have connection for the auditory pathway by the inferior colliculus. One study of hallucination noted activity in ...
commissure of inferior colliculus. CnF. cuneiform nucleus. cnr. cochlear nerve root. cp. cerebral peduncle. Cu. cuneate nucleus ... inferior colliculus. icp. inferior cerebellar peduncle. ILL. intermediate nucleus of lateral lemniscus. InG/W. intermediate ... dorsal cochlear nucleus. DLL. dorsal nucleus of lateral lemniscus. DpG/Wh. deep gray/white layers of superior colliculus. DPO. ... brachium of the inferior colliculus. Cb. cerebellum. CG. central gray. ChAT. choline acetyltransferase. ChAT-IR. choline ...
NeuronsDorsalAnteroventral cochlear nucleusNerveBrainstemCochleaMidbrainThalamusNuclei of the lateral lemniscusProjectionsIpsilateral cochlear nucleusPrimary auditoMedial geniculateLateral lemniscus and inferior colliculusImplantsTrapezoid bodyPlasticityUnilateralBrachium of the infBushyINHIBITIONVentral cochlear nucleiCentral auditoryPathwayTinnitusPortion of the cochlearAfferentResponsesExcitatoryNuclear complexElectrical stimulationInhibitoryDeafnessImplant UsersSynapticBasilar membraneSuperior olivaryHuman cochlearElectrodesTonotopic organizationOlivaryFrequency
- The present study investigated changes in tuning properties of inferior colliculus (IC) neurons following compression of the contralateral cochlear nucleus (CN). (edu.au)
- However, it is unknown whether neurons in the dorsal cochlear nucleus (DCN), the putative tinnitus-induction site, exhibit increased synchrony. (jneurosci.org)
- Increased cross-unit synchrony and bursting have been linked to tinnitus in several higher auditory stations but not in fusiform cells of the dorsal cochlear nucleus (DCN), key brainstem neurons in tinnitus generation. (jneurosci.org)
- This benefit, however, has been gained at a significant cost in the metabolic and mechanical vulnerability of cochlear hair cells and neurons. (pnas.org)
- However, the earliest stage where neurons appear to respond to pitch (as opposed to frequency - not the same thing) is probably the cochlear nucleus which is the first main integrative processing stage for auditory information. (bio.net)
- Age-related functional changes associated with glycine neurotransmission in dorsal cochlear nucleus (DCN) include altered intensity and temporal coding by DCN projection neurons. (biologists.org)
- Figure 3 from Immediate changes in tuning of inferior colliculus neurons following acute lesions of cat spiral ganglion. (semanticscholar.org)
- Acute spiral ganglion lesions change the tuning and tonotopic organization of cat inferior colliculus neurons. (semanticscholar.org)
- Layer V neurons represent the major output of AI to other cortical and subcortical regions (primarily the inferior colliculus). (nih.gov)
- G.T. and Rubel, E.W (1989) Effects of unilateral cochlea removal on anteroventral cochlear nucleus neurons in developing gerbils. (springer.com)
- Cochlear sensory cells and neurons receive efferent feedback from the olivocochlear (OC) system. (semanticscholar.org)
- On basis of these data, arrays of penetrating microelectrodes were designed to stimulate the primary auditory neurons in the ventral portion of the cochlear nucleus. (egms.de)
- Low-frequency fluctuations in AN responses are accentuated by cochlear nucleus neurons which, either directly or via other brainstem nuclei, relay fluctuation profiles to the inferior colliculus (IC). (springer.com)
- The physiological role of pre- and postsynaptic GABA(B) receptors in membrane excitability and synaptic transmission of neurons in the rat's dorsal cortex of the inferior colliculus. (nih.gov)
- GABA inputs control discharge rate primarily within frequency receptive fields of inferior colliculus neurons. (nih.gov)
- Plasticity of response properties of inferior colliculus neurons following acute cochlear damage. (nih.gov)
- Synaptic response patterns of neurons in the cortex of rat inferior colliculus. (nih.gov)
- We quantified both peripheral hearing loss and spontaneous activity in single neurons of the contralateral inferior colliculus in a guinea-pig model 1 week after a unilateral partial deafness induced by cochlear mechanical lesion. (nih.gov)
- Current opinion holds that neural events that give rise to the perception or exacerbation of tinnitus are likely to begin with anomalous or altered neural activity that originates from within the inner ear (cochlea), beginning with a preliminary lesion or insult to the peripheral sensory neural machinery (Type-I neurons) innervating the cochlear end-organ. (hearinghealthmatters.org)
- The descending branches of those same nerve fibers make contact as pericellular nests of boutons terminaux or boutons en passage neurons of different classes within PVCN and DCN, and here the transformations are quite different from those in AVCN. (scribd.com)
- 7,11) The third migratory pathway is formed by neurons destined to become the inferior olivary nucleus (IO). (thefreedictionary.com)
- Our analysis of the responses of neurons in the midbrain to such sounds shows that neurons are selective for specific ranges of modulation rate, and recently my colleagues and I have shown using fMRI that modulation rate, as well as sound frequency, is mapped in the inferior colliculus. (ncl.ac.uk)
- We found that about 50% of c-Fos positive nuclei belonged to glutamatergic neurons (Fig. 2A) and about 50% to glycinergic cells (Fig. 2B) in both the anteroventral cochlear nucleus and in the lateral superior olive ipsilateral to the stimulation. (egms.de)
- In the colliculus inferior on the contralateral site about 45% of c-Fos positive nuclei belonged to glutamatergic cells and about 30% to glycinergic neurons. (egms.de)
- Remarkably, c-Fos is strongly expressed in neurons of the AVCN projecting to the inferior colliculus, but only rarely in cells of the LSO with the same target region. (egms.de)
- This study explored whether optical activation of the cochlear nucleus (CN) elicited responses in neurons in higher centers of the auditory pathway and whether it elicited an evoked response. (epfl.ch)
- The axons of the olivary neurons project via the lateral lemniscus to the inferior colliculi, where they synapse on neurons that project to the primary auditory cortex 1,2 . (vin.com)
- Neurons of spiral ganglion (Glut) → VIII→ dorsal & ventral cochlear N. (learnneurosurgery.com)
- The dorsal cochlear nucleus (DCN), a brainstem nucleus that receives direct input from the auditory nerve, is essential for tinnitus induction ( Kaltenbach, 2011 ). (jneurosci.org)
- The cochlear nucleus (CN) consists of a dorsal and ventral division (DCN, VCN) having three functionally and anatomically segregated outputs (for a review, see Young and Oertel, 2004 ). (biologists.org)
- Cant NB and Benson CG (2003) Parallel auditory pathways: projection patterns of the different neuronal populations in the dorsal and ventral cochlear nuclei. (springer.com)
- The surface depth of the human ventral cochlear nucleus (VCN) varied over the ventro-dorsal extension between 0.09 to 10,71mm. (egms.de)
- the dorsal cochlear nucleus was smaller and more flat (mean: 4.1x0.8x1.8 mm). (egms.de)
- Arnott RH, Wallace MN, Shackleton TM, Palmer AR (2004) Onset neurones in the anteroventral cochlear nucleus project to the dorsal cochlear nucleus. (springer.com)
- The dorsal cochlear nucleus is the first site of multisensory convergence in mammalian auditory pathways. (sciencemag.org)
- We delivered repeated bimodal auditory-somatosensory stimulation to the dorsal cochlear nucleus of guinea pigs with tinnitus, choosing a stimulus interval known to induce long-term depression (LTD). Twenty minutes per day of LTD-inducing bimodal (but not unimodal) stimulation reduced physiological and behavioral evidence of tinnitus in the guinea pigs after 25 days. (sciencemag.org)
- Bimodal auditory-somatosensory stimulation that induces LTD in the dorsal cochlear nucleus may hold promise for suppressing chronic tinnitus, which reduces quality of life for millions of tinnitus sufferers worldwide. (sciencemag.org)
- Stellate/multipolar cells form the projection to both inferior colliculi (central nucleus and dorsal cortex), and synapse in a banded pattern, following the tonotopy of the region . (wikidoc.org)
- Lesions can involve the substantia nigra, periaqueductal gray matter within the midbrain, inferior colliculus, inferior olivary nuclei, inferior cerebellar peduncles, medulla, solitary tract in the medulla, central tegmental tract and reticular formation in the dorsal pons. (thefreedictionary.com)
- Pubmed ID: 12486183 It is known that the dorsal cochlear nucleus and medial geniculate body in the auditory system receive significant inputs from somatosensory and visual-motor sources, but the purpose of such inputs is not totally understood. (jove.com)
- We demonstrate that the dorsal cochlear nucleus and the small cell cap of the ventral cochlear nucleus have a direct projection to the medial division of the medial geniculate body. (jove.com)
- Here, we aim to identify and quantify the set of proteins in the hf and lf areas of four auditory brainstem regions of rats or mice: the dorsal cochlear nucleus, the medial nucleus of the trapezoid body, the lateral superior olive, and the inferior colliculus. (uni-kl.de)
- Several lines of experimental evidence lead to the conjecture that these response types reflect a dominant excitatory input from the medial superior olive, the lateral superior olive and the dorsal cochlear nucleus, respectively. (rochester.edu)
- The axons from the low-frequency region of the cochlea project to the ventral portion of the dorsal cochlear nucleus and the ventrolateral portions of the anteroventral cochlear nucleus. (wikipedia.org)
- The axons from the high-frequency region project to the dorsal portion of the anteroventral cochlear nucleus and the uppermost dorsal portions of the dorsal cochlear nucleus. (wikipedia.org)
- The fusiform cells of the Dorsal cochlear nucleus , which are thought to contribute to localization in elevation, bypass the SOC and project directly to the inferior colliculus . (academic.ru)
- dorsal cochlear nucleus 4. (edoctoronline.com)
- The inferior colliculus is the first place where vertically orienting data from the fusiform cells in the dorsal cochlear nucleus can finally synapse with horizontally orienting data. (blogspot.com)
- Of course, there is some lateralization, the dorsal projections (containing vertical data) only project to the contralateral inferior colliculus. (blogspot.com)
- The structures tested were the auditory nerve, anteroventral cochlear nucleus, superior olivary complex, inferior colliculus, and primary auditory cortex. (nih.gov)
- Projections to the inferior colliculus from the anteroventral cochlear nucleus in the cat: possible substrates for binaural interaction. (wikidoc.org)
- 1981). "Tonotopic organization of the anteroventral cochlear nucleus of the cat. (wikidoc.org)
- C-Fos expressing cells in the anteroventral cochlear nucleus (AVCN), the lateral superior olive (LSO) and the colliculus inferior (IC) were characterized by the neurotransmitter they use and by the area to which they send their axon. (egms.de)
- The superior olivary complex is generally located in the pons , but in human extends from the rostral medulla to the mid-pons [ 1 ] and receives projections predominantly from the anteroventral cochlear nucleus via the trapezoid body, although the posteroventral nucleus projects to the SOC via the intermediate acoustic stria. (academic.ru)
- Cochlear nerve fibers (30,000+) each have a most sensitive frequency and respond over a wide range of levels. (wikipedia.org)
- The cochlear nerve arises from the vestibulocochlear nerve for transmission to the cochlear nuclear complex at the brainstem pontomedullary junction. (slavery.org.uk)
- In previous studies, we demonstrated that acute lesions the spiral ganglion (SG), the cells of origin of the auditory nerve (AN), change the frequency organization of the inferior colliculus central nucleus (ICC) and primary auditory cortex (AI). (semanticscholar.org)
- The unmyelinated lateral (L)OC fibers target ipsilateral cochlear nerve dendrites and pharmacological studies suggest the LOC's dopaminergic component may protect these dendrites from excitotoxic effects of acoustic overexposure. (semanticscholar.org)
- Loss of alpha CGRP reduces sound-evoked activity in the cochlear nerve. (semanticscholar.org)
- Cochlear nucleus (CN), the exclusive destination of the auditory nerve, is the gateway for all central processing of auditory information. (mit.edu)
- Brain, cochlear nerve, and temporal bone abnormalities were described and tabulated. (ajnr.org)
- Cochlear and hindbrain abnormalities are significantly more common among patients with ANSD with bilateral CND compared with those with at least 1 intact cochlear nerve. (ajnr.org)
- Recently, we reported finding a high prevalence of brain and cochlear nerve pathology on cranial MR imaging in a large cohort of children with ANSD. (ajnr.org)
- 10 CND, defined as a small or absent cochlear nerve, represents a severe and literal form of ANSD. (ajnr.org)
- The study of brainstem auditory evoked potentials (BAEP) allows obtaining the electrophysiological activity generated in the cochlear nerve to the inferior colliculus. (scielo.br)
- The ventral cochlear nucleus (or anterior , or accessory ), placed between the two divisions of the cochlear nerve , is on the ventral aspect of the inferior peduncle . (wikidoc.org)
- Bushy cells in the anterior ventral cochlear nucleus (AVCN), which receive end bulbs of held from auditory nerve fibers, project to the superior olivary complex through the trapezoid body and intermediate acoustic stria. (wikidoc.org)
- Cochlear Nuclei All auditory nerve fibers terminate within the cochlear nuclei (CN), which comprise highly complex groupings of cells that together form a protuberance on the lateral surface of the brain stem at the medullopontine junction. (scribd.com)
- This highly specialized synaptic arrangement, which is characterized by little convergence from disparate regions of the cochlear partition, is important in preserving temporal information transmitted by auditory nerve fibers. (scribd.com)
- The evoked potential is generated in the cochlea, goes through the cochlear nerve, through the cochlear nucleus, superior olivary complex, lateral lemniscus, to the inferior colliculus in the midbrain, on to the medial geniculate body, and finally to the auditory cortex. (thefreedictionary.com)
- I wave originated from the peripheral portion of eighth cranial nerve adjacent to cochlea, II wave from cochlear nucleus, III wave from superior olivary nucleus, IV wave from lateral lemniscus, and V wave from inferior colliculus. (thefreedictionary.com)
- showed that the trigeminal nerve also innervates the cochlear nucleus and the superior olivary complex . (thefreedictionary.com)
- To explain the behavior of the slope-sensitive phasic cells, we have developed an auditory model, consisting of six stages: the inner hair cell (IHC), the primary auditory nerve (AN), the ventral cochlear nucleus (VCN), the inferior colliculus (IC), the medial geniculate body (MGB), and the A1 neuron. (actapress.com)
- The Cochlear nerve (n. (statemaster.com)
- The vestibular nerve is one of the two branches of the Vestibulocochlear nerve (the cochlear nerve is the other. (statemaster.com)
- The nerve splits into two large divisions - the cochlear nerve and the vestibular nerve . (statemaster.com)
- Broadly speaking, the cochlear nerve innervates the cochlea , while the vestibular nerve goes to the vestibular apparatus . (statemaster.com)
- Cochlear implants (CI) are a powerful tool to restore auditory input to the brain by direct electrical stimulation of the auditory nerve after deafness caused by the degeneration of the cochlear hair cells. (egms.de)
- Once the nerve impulse is generated in the cochlea, the signal travels along the acoustic nerve to the cochlear nuclei. (vin.com)
- On the right side, several stages of the bat's auditory system are labeled-the cochlea, auditory nerve (AN), cochlear nucleus (CN), nucleus of the lateral lemniscus (NLL), and inferior colliculus (IC). (scholarpedia.org)
- E) A photomicrograph of a cross-section of the right cochlea (same orientation as in D) showing the auditory nerve (AN) and cochlear nucleus (CN). (scholarpedia.org)
- Auditory pathways start from the auditory nerve (wave I) to the cochlear nuclei (wave II) in the medulla to the superior olivary complex (wave III) in the pons and end in the inferior colliculus (waves IV and V) in the midbrain. (biomedcentral.com)
- As illustrated in Fig. 1, incoming information about the acoustic environment enters the brain via the auditory nerve (AN), whose fibers terminate in the cochlear nucleus (CN). (rochester.edu)
- Cochlear nerve is in center, shown as striped. (wikipedia.org)
- Part of the cochlear division of the acoustic nerve , highly magnified. (wikipedia.org)
- The cochlear nerve (also auditory or acoustic neuron ) is one of two parts of the vestibulocochlear nerve , a cranial nerve present in amniotes , the other part being the vestibular nerve. (wikipedia.org)
- The cochlear nerve carries auditory sensory information from the cochlea of the inner ear directly to the brain . (wikipedia.org)
- In humans, there are on average 30,000 nerve fibers within the cochlear nerve. (wikipedia.org)
- The cell bodies of the cochlear nerve lie within the cochlea and collectively form the spiral ganglion , named for the spiral shape it shares with the cochlea. (wikipedia.org)
- In mammals, cochlear nerve fibers are classified as either type I or type II. (wikipedia.org)
- In mammals, the axons from each cochlear nerve terminate in the cochlear nuclear complex that is ipsilaterally located in the medulla of the brainstem. (wikipedia.org)
- The inferior colliculus lies caudal to its counterpart - the superior colliculus - above the trochlear nerve, and at the base of the projection of the medial geniculate nucleus (MGN) and the lateral geniculate nucleus (LGN). (blogspot.com)
- Remember that cochlear nerve arises from bipolar cells from the spiral ganglion. (learnneurosurgery.com)
- This involves extracellular, single-unit recordings from the auditory nerve, cochlear nucleus, olivary complex and inferior colliculus, and in vivo patch-clamping in the auditory brainstem. (neuro.nl)
- It is our aim to find out the mechanisms behind this integration by measuring responses of the cochlear nucleus and comparing them to those of the auditory nerve. (neuro.nl)
- The inferior colliculus connects brainstem auditory centers to the medial geniculate body in the posterior thalamus from which the rather disperse acoustic radiation projects to the primary auditory cortex. (slavery.org.uk)
- Moore, D.R. (1990) Auditory brainstem of the ferret: Early cessation of developmental sensitivity to cochlear removal in the cochlear nucleus. (springer.com)
- Moore, D.R. (1994) Auditory brainstem of the ferret: Long survival following cochlear removal progressively changes projections from the cochlear nucleus to the inferior colliculus. (springer.com)
- The first major increase occurred between the lower brainstem and inferior colliculus, and the second between the inferior colliculus and auditory cortex. (nih.gov)
- A few studies have identified cholinergic effects in other brainstem auditory nuclei, such as the inferior colliculus (e.g. (pubmedcentralcanada.ca)
- 1) Anatomical variability at the site of stimulation The variability in orientation, size and shape of the cochlear nucleus was investigated in 25 human brainstem specimens with a precision of 4μm. (egms.de)
- The rostral part, which starts from the cortical centers to thalamic nuclei and continues into collicular pathways in rostral brainstem, which sends its neural fibers to the main collicular nuclei especially inferior colliculus. (bioportfolio.com)
- The tip electrodes of a cochlear implant Type-CI24M, kindly provided by Cochlear AG Basel, Switzerland were inserted into the basal turn of the cochlea and it was aimed to obtain an initial electrically evoked maximal brainstem response amplitude in the range of 5-8 μV. (egms.de)
- these pathways ascend through a multitude of other brainstem nuclei including the superior olive (SO) and nuclei of the lateral lemniscus (NLL) before converging upon the inferior colliculi (IC). (rochester.edu)
- The central axons form synaptic connections with cells in the cochlear nucleus of the brainstem. (wikipedia.org)
- The inferior colliculus is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. (blogspot.com)
- The input connections to the inferior colliculus are composed of many brainstem nuclei. (blogspot.com)
- 4. An implantable apparatus of claim 1 wherein the stimuli is delivered to the cochlea, inferior colliculus, the Subthalamic Nucleus (STN), the Globus Pallidus (GPi), and/or the Thalamus of the implantee. (google.ca)
- Kitzes, L.M., Kageyama, G.H., Semple, M.N. and Kil, J. (1995) Development of ectopic projections from the ventral cochlear nucleus to the superior olivary complex induced by neonatal ablation of the contralateral cochlea. (springer.com)
- ANSD is a relatively new term used to describe the auditory characteristics of hearing-impaired patients who exhibit normal cochlear outer hair cell function but aberrant or disordered neural conduction in other sites deep to the cochlea along the auditory pathway. (ajnr.org)
- A middle ear cholesteatoma in one patient invaded the cochlea and resulted in marked cochlear enhancement due to granulation tissue. (ajnr.org)
- The axons from the intermediate frequency region project to intermediate targets, such that tonotopy is preserved between the cochlea and the cochlear nuclei. (wikipedia.org)
- The inferior colliculus (IC) and the locus coeruleus (LC) are two midbrain nuclei that integrate multimodal information and play a major role in novelty detection to elicit an orienting response. (frontiersin.org)
- Age-related presynaptic changes in the cochlear nucleus include reduced glycine levels, while in the auditory midbrain and cortex, GABA synthesis and release are altered. (biologists.org)
- The inferior colliculus, the primary nucleus in the mammalian auditory midbrain, occupies a central position in the ascending auditory pathway. (mit.edu)
- A main focus of my lab is the functional organisation of the auditory midbrain, the inferior colliculus. (ncl.ac.uk)
- The more posterior portion of the midbrain consists of the superior (visual) and inferior (auditory) collicululi which are directly related to the thalamus, and the red nucleus which receives motor fibers from the cerebellum and frontal and parietal lobe. (brainmind.com)
- The inferior colliculi (Latin, lower hills) together with the superior colliculi form the eminences of the corpora quadrigemina, and also part of the tectal region of the midbrain. (blogspot.com)
- The inferior colliculi of the midbrain are located just below the visual processing centers known as the superior colliculi. (blogspot.com)
- superior colliculus: orientation and behavior toward objects, as well as eye movements (saccade)) areas, Pons (superior cerebellar peduncle: thalamus to cerebellum connection/hear sound and learn behavioral response), spinal cord (periaqueductal grey: hear sound and instinctually move), and thalamus. (wikipedia.org)
- The PBG projects to the superior colliculus and visual thalamus (e.g. (pubmedcentralcanada.ca)
- its head forms the base of the anterior horn of the lateral ventricle, and its tail follows the ventricle as it arches over the thalamus and curves down and outward to become the inferior horn of the lateral ventricle, inside the temporal lobe of the cerebral hemisphere. (thefreedictionary.com)
- Direct Projections from Cochlear Nuclear Complex to Auditory Thalamus in the Rat The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. (jove.com)
- The colliculi then provide most, if not all, of the input to the auditory thalamus (MGB) and cortex (A1). (rochester.edu)
- Here we have studied age-dependent changes in the expression of α-amino-3-hydroxy-5-methyl-4-isoxazole (AMPA) and N -methyl- d -aspartate (NMDA) receptor subunits in the cochlear nucleus complex (CN), the superior olivary complex (SOC), the nuclei of the lateral lemniscus, and the inferior colliculus of the developing rat. (wiley.com)
- 1993). "Projections of physiologically characterized spherical bushy cell axons from the cochlear nucleus of the cat: evidence for delay lines to the medial superior olive. (wikidoc.org)
- In the present study, we have used auditory neurophysiology, double labeling with anterograde tracers, and retrograde tracers to investigate the ascending projections of the cochlear nuclear complex. (jove.com)
- These direct projections from the cochlear nucleus complex bypass the inferior colliculus and are widely distributed within the medial division of the medial geniculate, suggesting that the projection is not topographic. (jove.com)
- The projections of the medial superior olive terminate densely in the ipsilateral central nucleus of the inferior colliculus. (academic.ru)
- A member of RAB family of small GTPase (RAB3A) was decreased in both ipsilateral cochlear nucleus and contralateral inferior colliculus. (nih.gov)
- [ 8 ] The LSO receives excitatory, glutamatergic input from spherical bushy cells in the ipsilateral cochlear nucleus and inhibitory, glycinergic input from the medial nucleus of the trapezoid body (MNTB). (academic.ru)
- Hearing effect pulsed microwave exposure increases rat brain glucose metabolism by [ 14 C] 2-deoxy-D-glucose with particular auditory pathway prominence in the cochlear nucleus, the superior olivary complex, the inferior colliculus, and medial geniculate body. (slavery.org.uk)
- In this talk I highlight how we have leveraged these techniques to investigate the organization of the human auditory pathway at an unprecedented level of detail.We reliably measure fMRI responses to natural sounds from the cochlear nucleus, superior olive, inferior colliculus and medial geniculate body in single subjects. (ehbea.com)
- In addition, the IC receives descending inputs from the auditory cortex, medial geniculate body (MGB), and superior colliculus (SC). (blogspot.com)
- This inferior colliculus contralateral to the ear it is receiving the most information from, then projects to its ipsilateral medial geniculate nucleus. (blogspot.com)
- The medial geniculate body (MGB) is the output connection from interior colliculus and the last subcortical way station. (blogspot.com)
- Cochlear implants. (univr.it)
- Experimental implants: inferior colliculus implants and PABI. (univr.it)
- This framework for understanding neural coding and control mechanisms for supra-threshold hearing suggests strategies for the design of novel hearing aid signal-processing and electrical stimulation patterns for cochlear implants. (springer.com)
- In prelingually deaf children with cochlear implants, auditory cortex responds poorly to auditory signals because it has been permanently taken over by cross-modal inputs [ 12 ]. (hindawi.com)
- As a result of this maladaptive cross-modal plasticity, deaf patients with cochlear implants exhibit poorer performance in auditory speech recognition tasks than hearing controls [ 9 , 13 ]. (hindawi.com)
- The present invention relates to medical implants, and more specifically to cochlear implant systems. (freepatentsonline.com)
- Effect of wireless remote microphone application on speech discrimination in noise in children with cochlear implants. (bioportfolio.com)
- Cochlear implants (CIs) restore some spatial advantages for speech understanding in noise to individuals with single-sided deafness (SSD). (bioportfolio.com)
- Cochlear implants are even seen as a modern medical miracle! (brightkite.com)
- Single-unit responses in the inferior colliculus: effects of neonatal unilateral cochlear ablation. (semanticscholar.org)
- Cochlear anomalies were more common in patients with bilateral versus unilateral CND ( P = .01). (ajnr.org)
- 7. Blasco, M. A., Redleaf, M. I:. Cochlear implantation in unilateral sudden deafness improves tinnitus and speech comprehension: Meta-analysis and systematic review. (prolekare.cz)
- Loss of synaptic inhibition in the superior olivary complex (SOC) and the inferior colliculus (IC) likely affect the ability of aged animals to localize sounds in their natural environment. (biologists.org)
- Iontophoresis in vivo demonstrates a key role for GABA(A) and glycinergic inhibition in shaping frequency response areas in the inferior colliculus of guinea pig. (nih.gov)
- Presynaptic modulation of GABAergic inhibition by GABA(B) receptors in the rat's inferior colliculus. (nih.gov)
- Role of GABAergic inhibition in the coding of interaural time differences of low-frequency sounds in the inferior colliculus. (nih.gov)
- Inhibitory mechanisms play a major role in the inferior colliculus, and upsetting the balance of inhibition is implicated as a cause of tinnitus. (ncl.ac.uk)
- Advanced age is commonly associated with progressive cochlear pathology and central auditory deficits, collectively known as presbycusis. (nih.gov)
- The cochlear nucleus is the first 'relay station' of the central auditory system and receives mainly ipsilateral afferent input. (wikipedia.org)
- Many studies have reported plastic changes in central auditory frequency organization after chronic cochlear lesions. (elsevier.com)
- This parallel route in the auditory pathway is mainly devoted to sound localization, and also joins the lateral lemniscus, which proceeds to the inferior colliculus. (slavery.org.uk)
- Our study demonstrates a strategy for optogenetic stimulation of the auditory pathway in rodents and lays the groundwork for future applications of cochlear optogenetics in auditory research and prosthetics. (jci.org)
- Twenty minutes per day of bimodal stimulation to induce LTD in the cochlear nucleus reduced physiological and behavioral evidence of tinnitus in the animals. (sciencemag.org)
- Reorganization of Mn2+ uptake in the superior olivary complex and cochlear nucleus was dependent upon tinnitus status. (cdc.gov)
- Ventral nuclei of lateral lemniscus help the inferior colliculus (IC) decode amplitude modulated sounds by giving both phasic and tonic responses (short and long notes, respectively). (wikipedia.org)
- With the breadth of possible pathophysiologic mechanisms, ANSD can manifest with a wide variety and degree of symptoms and findings, 8 but these various phenotypes may exhibit indistinguishable audiometric and electrophysiologic results (ie, the presence of otoacoustic emissions and/or a cochlear microphonic with absent or grossly abnormal auditory brain stem responses). (ajnr.org)
- This study investigated the comparative number of single units exhibiting excitatory responses in the central nucleus of the inferior colliculus to monaural electric versus acoustic stimuli. (edu.au)
- We measured the contribution of inferior colliculus (IC) sites to perception using combined recording and electrical stimulation. (jneurosci.org)
- The electrode shell includes an interior volume that partially encases an implant electrode so that its electrode contacts are exposed for delivering electrical stimulation signals to the cochlear tissue. (freepatentsonline.com)
- 1. A cochlear implant device comprising: an electrode shell for insertion into a fixed position in cochlear tissue, the electrode shell including an interior volume for partially encasing an implant electrode so that a plurality of electrode contacts are exposed for delivering electrical stimulation signals to the cochlear tissue. (freepatentsonline.com)
- Approximation of the spatial spread of cochlear excitation by recording local field potentials (LFPs) in the inferior colliculus in response to suprathreshold optical, acoustic, and electrical stimuli indicated that optogenetic stimulation achieves better frequency resolution than monopolar electrical stimulation. (jci.org)
- For the development of future cochlear implant coding strategies a detailed understanding of the effects of electrical stimulation is required. (edu.au)
- Information about modulation is one of the main sounds attributes available to cochlear implant users. (ncl.ac.uk)
- My project will investigate the role of age on the success of cochlear implantation and auditory experience on the development of perceptual (phoneme) categories in prelingually deaf cochlear implant users. (hearinghealthfoundation.org)
- The research will demonstrate the degree to which these cochlear implant users can categorize speech sounds, which will improve our understanding of speech perception and the effects of early auditory deprivation on the overall success of cochlear implantation. (hearinghealthfoundation.org)
- This project will study the nature and extent of this impact on the development of categorical speech perceptions in prelingually deaf cochlear implant users. (hearinghealthfoundation.org)
- This finding, together with previous evidence that type II afferents respond weakly to synaptic transmission from cochlear hair cells, and normally are insensitive to sound, supports the identification of type II afferents as cochlear nociceptors, mediating the sensation of painfully loud sound. (pnas.org)
- Metabotropic glutamate receptors modulate glutamatergic and GABAergic synaptic transmission in the central nucleus of the inferior colliculus. (nih.gov)
- cochlear canal), and scala tympani (lower), and two membranes reissner's membrane between the vestibular and cochlear and the basilar membrane between the tympanic and cochlear. (brightkite.com)
- The sensory transduction occurs in the organ of Corti, which is situated in the scala media en separated from the scala vestibuli and the scala tympani by reissner's membrane and the basilar membrane respectively. (vin.com)
- The superior olivary complex (SOC), in pons, is the first convergence of the left and right cochlear pulses. (wikipedia.org)
- 2 , 3 Waves III and IV are believed to be generated in the cochlear nucleus and the superior olivary complex, respectively. (dovepress.com)
- The caudal part includes the olivocochlear bundle, which originates from the superior olivary complex and terminates on the cochlear hair cells. (bioportfolio.com)